id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017585-0llgr357	Chappell, Mark C.	Role of ACE, ACE2 and Neprilysin in the Kidney	2007		.txt	text/plain	7578	336	43	Although the emergence of receptor subtypes distinguishes the distinct signaling pathways of Ang II and Ang-(1-7), the post-renin enzymes that form and degrade these peptides must be considered in lieu of the overall regulation of the functional RAAS within the kidney. ACE, angiotensin converting enzyme; EPs, endopeptidases; NEP, neprilysin demonstration of endogenous levels of the peptide in the kidney, circulation and other tissues (Nagata et al 2006) . Thus, in addition to the proximal tubule epithelium, the glomerulus may be a second key site within the kidney where ACE2 may influence the local expression of angiotensin peptides and renal function. There are few studies on the regulation of the Ang-(1-7) receptor, although chronic ACE or AT 1 blockade reduced mas mRNA expression in the renal cortex of the Ren2 Lewis congenic rat .	./cache/cord-017585-0llgr357.txt	./txt/cord-017585-0llgr357.txt