id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_dqn2txozcvhufgeljzjxcvc7mu	Nk Stepto	Exercise and insulin resistance in PCOS: muscle insulin signalling and fibrosis	2020	14	.pdf	application/pdf	10793	2283	67	Exercise and insulin resistance in PCOS: muscle Objective: Mechanisms of insulin resistance in polycystic ovary syndrome (PCOS) remain muscle in the overweight women with PCOS but were unresponsive to exercise training and hyperandrogenism in PCOS-specific insulin resistance in lean and overweight women. PCOS-specific insulin signalling defects were isolated to mTOR, while gene expression implicated TGFβ ligand regulating a fibrosis in the PCOS-obesity synergy in insulin muscle insulin signalling and gene expression of the ECM Covariate adjusted statistical difference reported as: *significant fold increase with insulin stimulation P < 0.05 (and clear effect at Covariate adjusted statistical difference reported as: *significant fold increase with insulin stimulation P < 0.05 (and clear effect at 99%CL), **significant fold increase with insulin stimulation P < 0.01 (and clear effect at 99%CL), asignificantly different between group training response The women with PCOS from the exercise training subgroup had improved, but not rescued mTOR signalling https://figshare.com/articles/Supplementary_Material_Molecular_Mechanisms_of_Insulin_Resistance_in_Skeletal_Muscle_of_Women_with_PCOS/6726761 https://figshare.com/articles/Supplementary_Material_Molecular_Mechanisms_of_Insulin_Resistance_in_Skeletal_Muscle_of_Women_with_PCOS/6726761 https://figshare.com/articles/Supplementary_Material_Molecular_Mechanisms_of_Insulin_Resistance_in_Skeletal_Muscle_of_Women_with_PCOS/6726761	./cache/work_dqn2txozcvhufgeljzjxcvc7mu.pdf	./txt/work_dqn2txozcvhufgeljzjxcvc7mu.txt