id	sid	tid	token	lemma	pos
cord-321013-8pkrg0mx	1	1	key	key	JJ
cord-321013-8pkrg0mx	1	2	:	:	:
cord-321013-8pkrg0mx	1	3	cord-321013	cord-321013	NNP
cord-321013-8pkrg0mx	1	4	-	-	HYPH
cord-321013-8pkrg0mx	1	5	8pkrg0mx	8pkrg0mx	CD
cord-321013-8pkrg0mx	1	6	authors	author	NNS
cord-321013-8pkrg0mx	1	7	:	:	:
cord-321013-8pkrg0mx	1	8	McBride	McBride	NNP
cord-321013-8pkrg0mx	1	9	,	,	,
cord-321013-8pkrg0mx	1	10	Ruth	Ruth	NNP
cord-321013-8pkrg0mx	1	11	;	;	:
cord-321013-8pkrg0mx	1	12	van	van	NNP
cord-321013-8pkrg0mx	1	13	Zyl	Zyl	NNP
cord-321013-8pkrg0mx	1	14	,	,	,
cord-321013-8pkrg0mx	1	15	Marjorie	Marjorie	NNP
cord-321013-8pkrg0mx	1	16	;	;	:
cord-321013-8pkrg0mx	1	17	Fielding	Fielding	NNP
cord-321013-8pkrg0mx	1	18	,	,	,
cord-321013-8pkrg0mx	1	19	Burtram	Burtram	NNP
cord-321013-8pkrg0mx	1	20	C.	C.	NNP
cord-321013-8pkrg0mx	1	21	title	title	NN
cord-321013-8pkrg0mx	1	22	:	:	:
cord-321013-8pkrg0mx	1	23	The	the	DT
cord-321013-8pkrg0mx	1	24	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	1	25	Nucleocapsid	Nucleocapsid	NNP
cord-321013-8pkrg0mx	1	26	Is	be	VBZ
cord-321013-8pkrg0mx	1	27	a	a	DT
cord-321013-8pkrg0mx	1	28	Multifunctional	Multifunctional	NNP
cord-321013-8pkrg0mx	1	29	Protein	Protein	NNP
cord-321013-8pkrg0mx	1	30	date	date	NN
cord-321013-8pkrg0mx	2	1	:	:	:
cord-321013-8pkrg0mx	2	2	2014	2014	CD
cord-321013-8pkrg0mx	2	3	-	-	HYPH
cord-321013-8pkrg0mx	2	4	08	08	CD
cord-321013-8pkrg0mx	2	5	-	-	HYPH
cord-321013-8pkrg0mx	2	6	07	07	CD
cord-321013-8pkrg0mx	2	7	journal	journal	NN
cord-321013-8pkrg0mx	2	8	:	:	:
cord-321013-8pkrg0mx	3	1	Viruses	virus	NNS
cord-321013-8pkrg0mx	3	2	DOI	DOI	NNP
cord-321013-8pkrg0mx	3	3	:	:	:
cord-321013-8pkrg0mx	4	1	10.3390	10.3390	CD
cord-321013-8pkrg0mx	4	2	/	/	SYM
cord-321013-8pkrg0mx	4	3	v6082991	v6082991	NNP
cord-321013-8pkrg0mx	4	4	sha	sha	NNP
cord-321013-8pkrg0mx	4	5	:	:	:
cord-321013-8pkrg0mx	4	6	b190452f13e95ef0af0c07243e44a98371fe00eb	b190452f13e95ef0af0c07243e44a98371fe00eb	NNP
cord-321013-8pkrg0mx	4	7	doc_id	doc_id	CD
cord-321013-8pkrg0mx	4	8	:	:	:
cord-321013-8pkrg0mx	4	9	321013	321013	CD
cord-321013-8pkrg0mx	4	10	cord_uid	cord_uid	NN
cord-321013-8pkrg0mx	4	11	:	:	:
cord-321013-8pkrg0mx	5	1	8pkrg0mx	8pkrg0mx	CD
cord-321013-8pkrg0mx	6	1	The	the	DT
cord-321013-8pkrg0mx	6	2	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	6	3	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	6	4	(	(	-LRB-
cord-321013-8pkrg0mx	6	5	N	N	NNP
cord-321013-8pkrg0mx	6	6	)	)	-RRB-
cord-321013-8pkrg0mx	6	7	is	be	VBZ
cord-321013-8pkrg0mx	6	8	a	a	DT
cord-321013-8pkrg0mx	6	9	structural	structural	JJ
cord-321013-8pkrg0mx	6	10	protein	protein	NN
cord-321013-8pkrg0mx	6	11	that	that	WDT
cord-321013-8pkrg0mx	6	12	forms	form	VBZ
cord-321013-8pkrg0mx	6	13	complexes	complex	NNS
cord-321013-8pkrg0mx	6	14	with	with	IN
cord-321013-8pkrg0mx	6	15	genomic	genomic	JJ
cord-321013-8pkrg0mx	6	16	RNA	RNA	NNP
cord-321013-8pkrg0mx	6	17	,	,	,
cord-321013-8pkrg0mx	6	18	interacts	interact	VBZ
cord-321013-8pkrg0mx	6	19	with	with	IN
cord-321013-8pkrg0mx	6	20	the	the	DT
cord-321013-8pkrg0mx	6	21	viral	viral	JJ
cord-321013-8pkrg0mx	6	22	membrane	membrane	NN
cord-321013-8pkrg0mx	6	23	protein	protein	NN
cord-321013-8pkrg0mx	6	24	during	during	IN
cord-321013-8pkrg0mx	6	25	virion	virion	NN
cord-321013-8pkrg0mx	6	26	assembly	assembly	NN
cord-321013-8pkrg0mx	6	27	and	and	CC
cord-321013-8pkrg0mx	6	28	plays	play	VBZ
cord-321013-8pkrg0mx	6	29	a	a	DT
cord-321013-8pkrg0mx	6	30	critical	critical	JJ
cord-321013-8pkrg0mx	6	31	role	role	NN
cord-321013-8pkrg0mx	6	32	in	in	IN
cord-321013-8pkrg0mx	6	33	enhancing	enhance	VBG
cord-321013-8pkrg0mx	6	34	the	the	DT
cord-321013-8pkrg0mx	6	35	efficiency	efficiency	NN
cord-321013-8pkrg0mx	6	36	of	of	IN
cord-321013-8pkrg0mx	6	37	virus	virus	NN
cord-321013-8pkrg0mx	6	38	transcription	transcription	NN
cord-321013-8pkrg0mx	6	39	and	and	CC
cord-321013-8pkrg0mx	6	40	assembly	assembly	NN
cord-321013-8pkrg0mx	6	41	.	.	.
cord-321013-8pkrg0mx	7	1	Recent	recent	JJ
cord-321013-8pkrg0mx	7	2	studies	study	NNS
cord-321013-8pkrg0mx	7	3	have	have	VBP
cord-321013-8pkrg0mx	7	4	confirmed	confirm	VBN
cord-321013-8pkrg0mx	7	5	that	that	IN
cord-321013-8pkrg0mx	7	6	N	N	NNP
cord-321013-8pkrg0mx	7	7	is	be	VBZ
cord-321013-8pkrg0mx	7	8	a	a	DT
cord-321013-8pkrg0mx	7	9	multifunctional	multifunctional	JJ
cord-321013-8pkrg0mx	7	10	protein	protein	NN
cord-321013-8pkrg0mx	7	11	.	.	.
cord-321013-8pkrg0mx	8	1	The	the	DT
cord-321013-8pkrg0mx	8	2	aim	aim	NN
cord-321013-8pkrg0mx	8	3	of	of	IN
cord-321013-8pkrg0mx	8	4	this	this	DT
cord-321013-8pkrg0mx	8	5	review	review	NN
cord-321013-8pkrg0mx	8	6	is	be	VBZ
cord-321013-8pkrg0mx	8	7	to	to	TO
cord-321013-8pkrg0mx	8	8	highlight	highlight	VB
cord-321013-8pkrg0mx	8	9	the	the	DT
cord-321013-8pkrg0mx	8	10	properties	property	NNS
cord-321013-8pkrg0mx	8	11	and	and	CC
cord-321013-8pkrg0mx	8	12	functions	function	NNS
cord-321013-8pkrg0mx	8	13	of	of	IN
cord-321013-8pkrg0mx	8	14	the	the	DT
cord-321013-8pkrg0mx	8	15	N	N	NNP
cord-321013-8pkrg0mx	8	16	protein	protein	NN
cord-321013-8pkrg0mx	8	17	,	,	,
cord-321013-8pkrg0mx	8	18	with	with	IN
cord-321013-8pkrg0mx	8	19	specific	specific	JJ
cord-321013-8pkrg0mx	8	20	reference	reference	NN
cord-321013-8pkrg0mx	8	21	to	to	IN
cord-321013-8pkrg0mx	8	22	(	(	-LRB-
cord-321013-8pkrg0mx	8	23	i	i	NN
cord-321013-8pkrg0mx	8	24	)	)	-RRB-
cord-321013-8pkrg0mx	8	25	the	the	DT
cord-321013-8pkrg0mx	8	26	topology	topology	NN
cord-321013-8pkrg0mx	8	27	;	;	,
cord-321013-8pkrg0mx	8	28	(	(	-LRB-
cord-321013-8pkrg0mx	8	29	ii	ii	NN
cord-321013-8pkrg0mx	8	30	)	)	-RRB-
cord-321013-8pkrg0mx	8	31	the	the	DT
cord-321013-8pkrg0mx	8	32	intracellular	intracellular	JJ
cord-321013-8pkrg0mx	8	33	localization	localization	NN
cord-321013-8pkrg0mx	8	34	and	and	CC
cord-321013-8pkrg0mx	8	35	(	(	-LRB-
cord-321013-8pkrg0mx	8	36	iii	iii	NN
cord-321013-8pkrg0mx	8	37	)	)	-RRB-
cord-321013-8pkrg0mx	9	1	the	the	DT
cord-321013-8pkrg0mx	9	2	functions	function	NNS
cord-321013-8pkrg0mx	9	3	of	of	IN
cord-321013-8pkrg0mx	9	4	the	the	DT
cord-321013-8pkrg0mx	9	5	protein	protein	NN
cord-321013-8pkrg0mx	9	6	.	.	.
cord-321013-8pkrg0mx	10	1	Coronaviruses	Coronaviruses	NNP
cord-321013-8pkrg0mx	10	2	(	(	-LRB-
cord-321013-8pkrg0mx	10	3	CoVs	CoVs	NNP
cord-321013-8pkrg0mx	10	4	)	)	-RRB-
cord-321013-8pkrg0mx	10	5	have	have	VB
cord-321013-8pkrg0mx	10	6	a	a	DT
cord-321013-8pkrg0mx	10	7	global	global	JJ
cord-321013-8pkrg0mx	10	8	distribution	distribution	NN
cord-321013-8pkrg0mx	10	9	and	and	CC
cord-321013-8pkrg0mx	10	10	infect	infect	VB
cord-321013-8pkrg0mx	10	11	a	a	DT
cord-321013-8pkrg0mx	10	12	variety	variety	NN
cord-321013-8pkrg0mx	10	13	of	of	IN
cord-321013-8pkrg0mx	10	14	human	human	JJ
cord-321013-8pkrg0mx	10	15	and	and	CC
cord-321013-8pkrg0mx	10	16	animal	animal	NN
cord-321013-8pkrg0mx	10	17	hosts	host	NNS
cord-321013-8pkrg0mx	10	18	,	,	,
cord-321013-8pkrg0mx	10	19	causing	cause	VBG
cord-321013-8pkrg0mx	10	20	illnesses	illness	NNS
cord-321013-8pkrg0mx	10	21	that	that	WDT
cord-321013-8pkrg0mx	10	22	range	range	VBP
cord-321013-8pkrg0mx	10	23	from	from	IN
cord-321013-8pkrg0mx	10	24	mostly	mostly	RB
cord-321013-8pkrg0mx	10	25	upper	upper	JJ
cord-321013-8pkrg0mx	10	26	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	10	27	tract	tract	NN
cord-321013-8pkrg0mx	10	28	infections	infection	NNS
cord-321013-8pkrg0mx	10	29	in	in	IN
cord-321013-8pkrg0mx	10	30	humans	human	NNS
cord-321013-8pkrg0mx	10	31	to	to	TO
cord-321013-8pkrg0mx	10	32	gastrointestinal	gastrointestinal	JJ
cord-321013-8pkrg0mx	10	33	tract	tract	JJ
cord-321013-8pkrg0mx	10	34	infections	infection	NNS
cord-321013-8pkrg0mx	10	35	,	,	,
cord-321013-8pkrg0mx	10	36	encephalitis	encephalitis	NN
cord-321013-8pkrg0mx	10	37	and	and	CC
cord-321013-8pkrg0mx	10	38	demyelination	demyelination	NN
cord-321013-8pkrg0mx	10	39	in	in	IN
cord-321013-8pkrg0mx	10	40	animals	animal	NNS
cord-321013-8pkrg0mx	10	41	;	;	:
cord-321013-8pkrg0mx	10	42	and	and	CC
cord-321013-8pkrg0mx	10	43	can	can	MD
cord-321013-8pkrg0mx	10	44	be	be	VB
cord-321013-8pkrg0mx	10	45	fatal	fatal	JJ
cord-321013-8pkrg0mx	10	46	[	[	-LRB-
cord-321013-8pkrg0mx	10	47	1	1	CD
cord-321013-8pkrg0mx	10	48	,	,	,
cord-321013-8pkrg0mx	10	49	2	2	CD
cord-321013-8pkrg0mx	10	50	]	]	-RRB-
cord-321013-8pkrg0mx	10	51	.	.	.
cord-321013-8pkrg0mx	11	1	The	the	DT
cord-321013-8pkrg0mx	11	2	International	International	NNP
cord-321013-8pkrg0mx	11	3	Committee	Committee	NNP
cord-321013-8pkrg0mx	11	4	for	for	IN
cord-321013-8pkrg0mx	11	5	Taxonomy	Taxonomy	NNP
cord-321013-8pkrg0mx	11	6	of	of	IN
cord-321013-8pkrg0mx	11	7	Viruses	Viruses	NNPS
cord-321013-8pkrg0mx	11	8	(	(	-LRB-
cord-321013-8pkrg0mx	11	9	ICTV	ICTV	NNP
cord-321013-8pkrg0mx	11	10	)	)	-RRB-
cord-321013-8pkrg0mx	11	11	reports	report	VBZ
cord-321013-8pkrg0mx	11	12	four	four	CD
cord-321013-8pkrg0mx	11	13	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	11	14	genera	genera	NN
cord-321013-8pkrg0mx	11	15	,	,	,
cord-321013-8pkrg0mx	11	16	namely	namely	RB
cord-321013-8pkrg0mx	11	17	Alphacoronaviruses	Alphacoronaviruses	NNP
cord-321013-8pkrg0mx	11	18	,	,	,
cord-321013-8pkrg0mx	11	19	Betacoronaviruses	Betacoronaviruses	NNP
cord-321013-8pkrg0mx	11	20	,	,	,
cord-321013-8pkrg0mx	11	21	Gammacoronaviruses	Gammacoronaviruses	NNP
cord-321013-8pkrg0mx	11	22	and	and	CC
cord-321013-8pkrg0mx	11	23	Deltacoronaviruses	Deltacoronaviruses	NNPS
cord-321013-8pkrg0mx	11	24	[	[	-LRB-
cord-321013-8pkrg0mx	11	25	3	3	CD
cord-321013-8pkrg0mx	11	26	]	]	-RRB-
cord-321013-8pkrg0mx	11	27	.	.	.
cord-321013-8pkrg0mx	12	1	CoVs	CoVs	NNP
cord-321013-8pkrg0mx	12	2	are	be	VBP
cord-321013-8pkrg0mx	12	3	enveloped	envelop	VBN
cord-321013-8pkrg0mx	12	4	single	single	RB
cord-321013-8pkrg0mx	12	5	-	-	HYPH
cord-321013-8pkrg0mx	12	6	stranded	stranded	JJ
cord-321013-8pkrg0mx	12	7	,	,	,
cord-321013-8pkrg0mx	12	8	positive	positive	JJ
cord-321013-8pkrg0mx	12	9	-	-	HYPH
cord-321013-8pkrg0mx	12	10	sense	sense	NN
cord-321013-8pkrg0mx	12	11	RNA	RNA	NNP
cord-321013-8pkrg0mx	12	12	viruses	virus	NNS
cord-321013-8pkrg0mx	12	13	with	with	IN
cord-321013-8pkrg0mx	12	14	genomes	genome	NNS
cord-321013-8pkrg0mx	12	15	ranging	range	VBG
cord-321013-8pkrg0mx	12	16	between	between	IN
cord-321013-8pkrg0mx	12	17	26.2	26.2	CD
cord-321013-8pkrg0mx	12	18	-	-	HYPH
cord-321013-8pkrg0mx	12	19	31.7	31.7	CD
cord-321013-8pkrg0mx	12	20	kb	kb	NNP
cord-321013-8pkrg0mx	12	21	,	,	,
cord-321013-8pkrg0mx	12	22	the	the	DT
cord-321013-8pkrg0mx	12	23	largest	large	JJS
cord-321013-8pkrg0mx	12	24	among	among	IN
cord-321013-8pkrg0mx	12	25	known	know	VBN
cord-321013-8pkrg0mx	12	26	RNA	RNA	NNP
cord-321013-8pkrg0mx	12	27	viruses	virus	NNS
cord-321013-8pkrg0mx	12	28	[	[	-LRB-
cord-321013-8pkrg0mx	12	29	4	4	CD
cord-321013-8pkrg0mx	12	30	]	]	-RRB-
cord-321013-8pkrg0mx	12	31	.	.	.
cord-321013-8pkrg0mx	13	1	This	this	DT
cord-321013-8pkrg0mx	13	2	large	large	JJ
cord-321013-8pkrg0mx	13	3	,	,	,
cord-321013-8pkrg0mx	13	4	capped	capped	JJ
cord-321013-8pkrg0mx	13	5	and	and	CC
cord-321013-8pkrg0mx	13	6	polyadenylated	polyadenylated	JJ
cord-321013-8pkrg0mx	13	7	genome	genome	NN
cord-321013-8pkrg0mx	13	8	contains	contain	VBZ
cord-321013-8pkrg0mx	13	9	seven	seven	CD
cord-321013-8pkrg0mx	13	10	OPEN	open	JJ
cord-321013-8pkrg0mx	13	11	ACCESS	access	NN
cord-321013-8pkrg0mx	13	12	common	common	JJ
cord-321013-8pkrg0mx	13	13	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	13	14	genes	gene	NNS
cord-321013-8pkrg0mx	13	15	in	in	IN
cord-321013-8pkrg0mx	13	16	the	the	DT
cord-321013-8pkrg0mx	13	17	following	follow	VBG
cord-321013-8pkrg0mx	13	18	conserved	conserve	VBN
cord-321013-8pkrg0mx	13	19	order	order	NN
cord-321013-8pkrg0mx	13	20	:	:	:
cord-321013-8pkrg0mx	13	21	5'-ORF1a	5'-orf1a	CD
cord-321013-8pkrg0mx	13	22	-	-	HYPH
cord-321013-8pkrg0mx	13	23	ORF1b	ORF1b	NNP
cord-321013-8pkrg0mx	13	24	-	-	HYPH
cord-321013-8pkrg0mx	13	25	S	S	NNP
cord-321013-8pkrg0mx	13	26	-	-	HYPH
cord-321013-8pkrg0mx	13	27	ORF3-E	ORF3-E	NNP
cord-321013-8pkrg0mx	13	28	-	-	HYPH
cord-321013-8pkrg0mx	13	29	M	M	NNP
cord-321013-8pkrg0mx	13	30	-	-	HYPH
cord-321013-8pkrg0mx	13	31	N-3	N-3	NNP
cord-321013-8pkrg0mx	13	32	'	'	POS
cord-321013-8pkrg0mx	13	33	[	[	-LRB-
cord-321013-8pkrg0mx	13	34	5	5	CD
cord-321013-8pkrg0mx	13	35	]	]	-RRB-
cord-321013-8pkrg0mx	13	36	.	.	.
cord-321013-8pkrg0mx	14	1	ORF1a	ORF1a	NNP
cord-321013-8pkrg0mx	14	2	/	/	SYM
cord-321013-8pkrg0mx	14	3	b	b	NNP
cord-321013-8pkrg0mx	14	4	encompasses	encompass	VBZ
cord-321013-8pkrg0mx	14	5	two	two	CD
cord-321013-8pkrg0mx	14	6	-	-	HYPH
cord-321013-8pkrg0mx	14	7	thirds	third	NNS
cord-321013-8pkrg0mx	14	8	of	of	IN
cord-321013-8pkrg0mx	14	9	the	the	DT
cord-321013-8pkrg0mx	14	10	genome	genome	NN
cord-321013-8pkrg0mx	14	11	and	and	CC
cord-321013-8pkrg0mx	14	12	produces	produce	VBZ
cord-321013-8pkrg0mx	14	13	a	a	DT
cord-321013-8pkrg0mx	14	14	genome	genome	NN
cord-321013-8pkrg0mx	14	15	-	-	HYPH
cord-321013-8pkrg0mx	14	16	length	length	NN
cord-321013-8pkrg0mx	14	17	mRNA	mrna	NN
cord-321013-8pkrg0mx	14	18	(	(	-LRB-
cord-321013-8pkrg0mx	14	19	mRNA1	mrna1	NN
cord-321013-8pkrg0mx	14	20	)	)	-RRB-
cord-321013-8pkrg0mx	14	21	that	that	WDT
cord-321013-8pkrg0mx	14	22	encodes	encode	VBZ
cord-321013-8pkrg0mx	14	23	two	two	CD
cord-321013-8pkrg0mx	14	24	overlapping	overlap	VBG
cord-321013-8pkrg0mx	14	25	viral	viral	JJ
cord-321013-8pkrg0mx	14	26	replicase	replicase	NN
cord-321013-8pkrg0mx	14	27	proteins	protein	NNS
cord-321013-8pkrg0mx	14	28	in	in	IN
cord-321013-8pkrg0mx	14	29	the	the	DT
cord-321013-8pkrg0mx	14	30	form	form	NN
cord-321013-8pkrg0mx	14	31	of	of	IN
cord-321013-8pkrg0mx	14	32	polyproteins	polyproteins	NNP
cord-321013-8pkrg0mx	14	33	1a	1a	NNP
cord-321013-8pkrg0mx	14	34	(	(	-LRB-
cord-321013-8pkrg0mx	14	35	pp1a	pp1a	NNP
cord-321013-8pkrg0mx	14	36	)	)	-RRB-
cord-321013-8pkrg0mx	14	37	and	and	CC
cord-321013-8pkrg0mx	14	38	pp1ab	pp1ab	NNP
cord-321013-8pkrg0mx	14	39	[	[	-LRB-
cord-321013-8pkrg0mx	14	40	6	6	CD
cord-321013-8pkrg0mx	14	41	]	]	-RRB-
cord-321013-8pkrg0mx	14	42	.	.	.
cord-321013-8pkrg0mx	15	1	These	these	DT
cord-321013-8pkrg0mx	15	2	polyproteins	polyprotein	NNS
cord-321013-8pkrg0mx	15	3	are	be	VBP
cord-321013-8pkrg0mx	15	4	formed	form	VBN
cord-321013-8pkrg0mx	15	5	as	as	IN
cord-321013-8pkrg0mx	15	6	a	a	DT
cord-321013-8pkrg0mx	15	7	result	result	NN
cord-321013-8pkrg0mx	15	8	of	of	IN
cord-321013-8pkrg0mx	15	9	a	a	DT
cord-321013-8pkrg0mx	15	10	-1	-1	JJ
cord-321013-8pkrg0mx	15	11	ribosomal	ribosomal	JJ
cord-321013-8pkrg0mx	15	12	frame	frame	NN
cord-321013-8pkrg0mx	15	13	shift	shift	NN
cord-321013-8pkrg0mx	15	14	that	that	WDT
cord-321013-8pkrg0mx	15	15	involves	involve	VBZ
cord-321013-8pkrg0mx	15	16	a	a	DT
cord-321013-8pkrg0mx	15	17	complex	complex	JJ
cord-321013-8pkrg0mx	15	18	pseudoknott	pseudoknott	NNP
cord-321013-8pkrg0mx	15	19	RNA	RNA	NNP
cord-321013-8pkrg0mx	15	20	structure	structure	NN
cord-321013-8pkrg0mx	15	21	[	[	-LRB-
cord-321013-8pkrg0mx	15	22	7	7	CD
cord-321013-8pkrg0mx	15	23	]	]	-RRB-
cord-321013-8pkrg0mx	15	24	and	and	CC
cord-321013-8pkrg0mx	15	25	are	be	VBP
cord-321013-8pkrg0mx	15	26	then	then	RB
cord-321013-8pkrg0mx	15	27	proteolytically	proteolytically	RB
cord-321013-8pkrg0mx	15	28	processed	process	VBN
cord-321013-8pkrg0mx	15	29	by	by	IN
cord-321013-8pkrg0mx	15	30	virally	virally	RB
cord-321013-8pkrg0mx	15	31	encoded	encode	VBN
cord-321013-8pkrg0mx	15	32	proteases	protease	NNS
cord-321013-8pkrg0mx	15	33	into	into	IN
cord-321013-8pkrg0mx	15	34	mature	mature	JJ
cord-321013-8pkrg0mx	15	35	nonstructural	nonstructural	JJ
cord-321013-8pkrg0mx	15	36	proteins	protein	NNS
cord-321013-8pkrg0mx	15	37	(	(	-LRB-
cord-321013-8pkrg0mx	15	38	nsp1	nsp1	NNS
cord-321013-8pkrg0mx	15	39	to	to	IN
cord-321013-8pkrg0mx	15	40	nsp16	nsp16	NNS
cord-321013-8pkrg0mx	15	41	)	)	-RRB-
cord-321013-8pkrg0mx	15	42	,	,	,
cord-321013-8pkrg0mx	15	43	which	which	WDT
cord-321013-8pkrg0mx	15	44	assemble	assemble	VBP
cord-321013-8pkrg0mx	15	45	to	to	TO
cord-321013-8pkrg0mx	15	46	form	form	VB
cord-321013-8pkrg0mx	15	47	a	a	DT
cord-321013-8pkrg0mx	15	48	membrane	membrane	NN
cord-321013-8pkrg0mx	15	49	-	-	HYPH
cord-321013-8pkrg0mx	15	50	associated	associate	VBN
cord-321013-8pkrg0mx	15	51	viral	viral	JJ
cord-321013-8pkrg0mx	15	52	replicase	replicase	NN
cord-321013-8pkrg0mx	15	53	-	-	HYPH
cord-321013-8pkrg0mx	15	54	transcriptase	transcriptase	NN
cord-321013-8pkrg0mx	15	55	complex	complex	NN
cord-321013-8pkrg0mx	15	56	(	(	-LRB-
cord-321013-8pkrg0mx	15	57	RTC	RTC	NNP
cord-321013-8pkrg0mx	15	58	)	)	-RRB-
cord-321013-8pkrg0mx	15	59	[	[	-LRB-
cord-321013-8pkrg0mx	15	60	6	6	CD
cord-321013-8pkrg0mx	15	61	,	,	,
cord-321013-8pkrg0mx	15	62	8	8	CD
cord-321013-8pkrg0mx	15	63	,	,	,
cord-321013-8pkrg0mx	15	64	9	9	CD
cord-321013-8pkrg0mx	15	65	]	]	-RRB-
cord-321013-8pkrg0mx	15	66	.	.	.
cord-321013-8pkrg0mx	16	1	The	the	DT
cord-321013-8pkrg0mx	16	2	last	last	JJ
cord-321013-8pkrg0mx	16	3	third	third	NN
cord-321013-8pkrg0mx	16	4	of	of	IN
cord-321013-8pkrg0mx	16	5	the	the	DT
cord-321013-8pkrg0mx	16	6	genome	genome	NN
cord-321013-8pkrg0mx	16	7	produces	produce	VBZ
cord-321013-8pkrg0mx	16	8	subgenomic	subgenomic	NNP
cord-321013-8pkrg0mx	16	9	(	(	-LRB-
cord-321013-8pkrg0mx	16	10	sg	sg	NNP
cord-321013-8pkrg0mx	16	11	)	)	-RRB-
cord-321013-8pkrg0mx	16	12	mRNAs	mrnas	XX
cord-321013-8pkrg0mx	16	13	that	that	WDT
cord-321013-8pkrg0mx	16	14	encode	encode	VBP
cord-321013-8pkrg0mx	16	15	the	the	DT
cord-321013-8pkrg0mx	16	16	four	four	CD
cord-321013-8pkrg0mx	16	17	structural	structural	JJ
cord-321013-8pkrg0mx	16	18	proteins	protein	NNS
cord-321013-8pkrg0mx	16	19	,	,	,
cord-321013-8pkrg0mx	16	20	spike	spike	NN
cord-321013-8pkrg0mx	16	21	(	(	-LRB-
cord-321013-8pkrg0mx	16	22	S	S	NNP
cord-321013-8pkrg0mx	16	23	)	)	-RRB-
cord-321013-8pkrg0mx	16	24	,	,	,
cord-321013-8pkrg0mx	16	25	envelope	envelope	NN
cord-321013-8pkrg0mx	16	26	(	(	-LRB-
cord-321013-8pkrg0mx	16	27	E	E	NNP
cord-321013-8pkrg0mx	16	28	)	)	-RRB-
cord-321013-8pkrg0mx	16	29	,	,	,
cord-321013-8pkrg0mx	16	30	membrane	membrane	NN
cord-321013-8pkrg0mx	16	31	(	(	-LRB-
cord-321013-8pkrg0mx	16	32	M	M	NNP
cord-321013-8pkrg0mx	16	33	)	)	-RRB-
cord-321013-8pkrg0mx	16	34	,	,	,
cord-321013-8pkrg0mx	16	35	and	and	CC
cord-321013-8pkrg0mx	16	36	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	16	37	(	(	-LRB-
cord-321013-8pkrg0mx	16	38	N	N	NNP
cord-321013-8pkrg0mx	16	39	)	)	-RRB-
cord-321013-8pkrg0mx	16	40	,	,	,
cord-321013-8pkrg0mx	16	41	as	as	RB
cord-321013-8pkrg0mx	16	42	well	well	RB
cord-321013-8pkrg0mx	16	43	as	as	IN
cord-321013-8pkrg0mx	16	44	a	a	DT
cord-321013-8pkrg0mx	16	45	number	number	NN
cord-321013-8pkrg0mx	16	46	of	of	IN
cord-321013-8pkrg0mx	16	47	accessory	accessory	NN
cord-321013-8pkrg0mx	16	48	proteins	protein	NNS
cord-321013-8pkrg0mx	16	49	[	[	-LRB-
cord-321013-8pkrg0mx	16	50	10	10	CD
cord-321013-8pkrg0mx	16	51	,	,	,
cord-321013-8pkrg0mx	16	52	11	11	CD
cord-321013-8pkrg0mx	16	53	]	]	-RRB-
cord-321013-8pkrg0mx	16	54	.	.	.
cord-321013-8pkrg0mx	17	1	Amino	amino	NN
cord-321013-8pkrg0mx	17	2	acid	acid	NN
cord-321013-8pkrg0mx	17	3	sequence	sequence	NN
cord-321013-8pkrg0mx	17	4	comparisons	comparison	NNS
cord-321013-8pkrg0mx	17	5	have	have	VBP
cord-321013-8pkrg0mx	17	6	shown	show	VBN
cord-321013-8pkrg0mx	17	7	that	that	IN
cord-321013-8pkrg0mx	17	8	CoV	cov	NN
cord-321013-8pkrg0mx	17	9	N	n	CD
cord-321013-8pkrg0mx	17	10	proteins	protein	NNS
cord-321013-8pkrg0mx	17	11	have	have	VBP
cord-321013-8pkrg0mx	17	12	three	three	CD
cord-321013-8pkrg0mx	17	13	distinct	distinct	JJ
cord-321013-8pkrg0mx	17	14	and	and	CC
cord-321013-8pkrg0mx	17	15	highly	highly	RB
cord-321013-8pkrg0mx	17	16	conserved	conserve	VBN
cord-321013-8pkrg0mx	17	17	domains	domain	NNS
cord-321013-8pkrg0mx	17	18	:	:	:
cord-321013-8pkrg0mx	17	19	two	two	CD
cord-321013-8pkrg0mx	17	20	structural	structural	JJ
cord-321013-8pkrg0mx	17	21	and	and	CC
cord-321013-8pkrg0mx	17	22	independently	independently	RB
cord-321013-8pkrg0mx	17	23	folded	fold	VBN
cord-321013-8pkrg0mx	17	24	structural	structural	JJ
cord-321013-8pkrg0mx	17	25	regions	region	NNS
cord-321013-8pkrg0mx	17	26	,	,	,
cord-321013-8pkrg0mx	17	27	namely	namely	RB
cord-321013-8pkrg0mx	17	28	the	the	DT
cord-321013-8pkrg0mx	17	29	N	n	CD
cord-321013-8pkrg0mx	17	30	terminal	terminal	NN
cord-321013-8pkrg0mx	17	31	domain	domain	NN
cord-321013-8pkrg0mx	17	32	(	(	-LRB-
cord-321013-8pkrg0mx	17	33	NTD	NTD	NNP
cord-321013-8pkrg0mx	17	34	/	/	SYM
cord-321013-8pkrg0mx	17	35	domain	domain	NN
cord-321013-8pkrg0mx	17	36	1	1	CD
cord-321013-8pkrg0mx	17	37	)	)	-RRB-
cord-321013-8pkrg0mx	17	38	and	and	CC
cord-321013-8pkrg0mx	17	39	C	c	NN
cord-321013-8pkrg0mx	17	40	-	-	HYPH
cord-321013-8pkrg0mx	17	41	terminal	terminal	NN
cord-321013-8pkrg0mx	17	42	domain	domain	NN
cord-321013-8pkrg0mx	17	43	(	(	-LRB-
cord-321013-8pkrg0mx	17	44	CTD	CTD	NNP
cord-321013-8pkrg0mx	17	45	/	/	SYM
cord-321013-8pkrg0mx	17	46	domain	domain	NN
cord-321013-8pkrg0mx	17	47	3	3	CD
cord-321013-8pkrg0mx	17	48	)	)	-RRB-
cord-321013-8pkrg0mx	17	49	,	,	,
cord-321013-8pkrg0mx	17	50	which	which	WDT
cord-321013-8pkrg0mx	17	51	are	be	VBP
cord-321013-8pkrg0mx	17	52	separated	separate	VBN
cord-321013-8pkrg0mx	17	53	by	by	IN
cord-321013-8pkrg0mx	17	54	a	a	DT
cord-321013-8pkrg0mx	17	55	intrinsically	intrinsically	RB
cord-321013-8pkrg0mx	17	56	disordered	disordered	JJ
cord-321013-8pkrg0mx	17	57	central	central	JJ
cord-321013-8pkrg0mx	17	58	region	region	NN
cord-321013-8pkrg0mx	17	59	(	(	-LRB-
cord-321013-8pkrg0mx	17	60	RNA	rna	NN
cord-321013-8pkrg0mx	17	61	-	-	HYPH
cord-321013-8pkrg0mx	17	62	binding	bind	VBG
cord-321013-8pkrg0mx	17	63	domain	domain	NN
cord-321013-8pkrg0mx	17	64	/	/	SYM
cord-321013-8pkrg0mx	17	65	domain	domain	NN
cord-321013-8pkrg0mx	17	66	2	2	CD
cord-321013-8pkrg0mx	17	67	)	)	-RRB-
cord-321013-8pkrg0mx	18	1	(	(	-LRB-
cord-321013-8pkrg0mx	18	2	Figure	figure	NN
cord-321013-8pkrg0mx	18	3	1	1	CD
cord-321013-8pkrg0mx	18	4	)	)	-RRB-
cord-321013-8pkrg0mx	18	5	;	;	:
cord-321013-8pkrg0mx	18	6	all	all	DT
cord-321013-8pkrg0mx	18	7	three	three	CD
cord-321013-8pkrg0mx	18	8	domains	domain	NNS
cord-321013-8pkrg0mx	18	9	have	have	VBP
cord-321013-8pkrg0mx	18	10	been	be	VBN
cord-321013-8pkrg0mx	18	11	shown	show	VBN
cord-321013-8pkrg0mx	18	12	in	in	IN
cord-321013-8pkrg0mx	18	13	different	different	JJ
cord-321013-8pkrg0mx	18	14	CoVs	covs	NN
cord-321013-8pkrg0mx	18	15	to	to	TO
cord-321013-8pkrg0mx	18	16	bind	bind	VB
cord-321013-8pkrg0mx	18	17	with	with	IN
cord-321013-8pkrg0mx	18	18	viral	viral	JJ
cord-321013-8pkrg0mx	18	19	RNA	RNA	NNP
cord-321013-8pkrg0mx	18	20	[	[	-LRB-
cord-321013-8pkrg0mx	18	21	12	12	CD
cord-321013-8pkrg0mx	18	22	]	]	-RRB-
cord-321013-8pkrg0mx	18	23	[	[	-LRB-
cord-321013-8pkrg0mx	18	24	13	13	CD
cord-321013-8pkrg0mx	18	25	]	]	-RRB-
cord-321013-8pkrg0mx	19	1	[	[	-LRB-
cord-321013-8pkrg0mx	19	2	14	14	CD
cord-321013-8pkrg0mx	19	3	]	]	-RRB-
cord-321013-8pkrg0mx	20	1	[	[	-LRB-
cord-321013-8pkrg0mx	20	2	15	15	CD
cord-321013-8pkrg0mx	20	3	]	]	-RRB-
cord-321013-8pkrg0mx	20	4	[	[	-LRB-
cord-321013-8pkrg0mx	20	5	16	16	CD
cord-321013-8pkrg0mx	20	6	]	]	-RRB-
cord-321013-8pkrg0mx	20	7	[	[	-LRB-
cord-321013-8pkrg0mx	20	8	17	17	CD
cord-321013-8pkrg0mx	20	9	]	]	-RRB-
cord-321013-8pkrg0mx	20	10	.	.	.
cord-321013-8pkrg0mx	21	1	[	[	-LRB-
cord-321013-8pkrg0mx	21	2	16	16	CD
cord-321013-8pkrg0mx	21	3	,	,	,
cord-321013-8pkrg0mx	21	4	18	18	CD
cord-321013-8pkrg0mx	21	5	,	,	,
cord-321013-8pkrg0mx	21	6	19	19	CD
cord-321013-8pkrg0mx	21	7	]	]	-RRB-
cord-321013-8pkrg0mx	21	8	.	.	.
cord-321013-8pkrg0mx	22	1	The	the	DT
cord-321013-8pkrg0mx	22	2	NTD	NTD	NNP
cord-321013-8pkrg0mx	22	3	is	be	VBZ
cord-321013-8pkrg0mx	22	4	divergent	divergent	JJ
cord-321013-8pkrg0mx	22	5	in	in	IN
cord-321013-8pkrg0mx	22	6	both	both	DT
cord-321013-8pkrg0mx	22	7	sequence	sequence	NN
cord-321013-8pkrg0mx	22	8	and	and	CC
cord-321013-8pkrg0mx	22	9	length	length	NN
cord-321013-8pkrg0mx	22	10	.	.	.
cord-321013-8pkrg0mx	23	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	23	2	has	have	VBZ
cord-321013-8pkrg0mx	23	3	been	be	VBN
cord-321013-8pkrg0mx	23	4	mapped	map	VBN
cord-321013-8pkrg0mx	23	5	for	for	IN
cord-321013-8pkrg0mx	23	6	Infectious	Infectious	NNP
cord-321013-8pkrg0mx	23	7	Bronchitis	Bronchitis	NNP
cord-321013-8pkrg0mx	23	8	Virus	Virus	NNP
cord-321013-8pkrg0mx	23	9	(	(	-LRB-
cord-321013-8pkrg0mx	23	10	IBV)-N	IBV)-N	NNP
cord-321013-8pkrg0mx	23	11	to	to	IN
cord-321013-8pkrg0mx	23	12	aa	aa	NNP
cord-321013-8pkrg0mx	23	13	19	19	CD
cord-321013-8pkrg0mx	23	14	-	-	SYM
cord-321013-8pkrg0mx	23	15	162	162	CD
cord-321013-8pkrg0mx	23	16	[	[	-LRB-
cord-321013-8pkrg0mx	23	17	20	20	CD
cord-321013-8pkrg0mx	23	18	]	]	-RRB-
cord-321013-8pkrg0mx	23	19	,	,	,
cord-321013-8pkrg0mx	23	20	for	for	IN
cord-321013-8pkrg0mx	23	21	Severe	severe	JJ
cord-321013-8pkrg0mx	23	22	Acute	acute	JJ
cord-321013-8pkrg0mx	23	23	Respiratory	Respiratory	NNP
cord-321013-8pkrg0mx	23	24	Syndrome	Syndrome	NNP
cord-321013-8pkrg0mx	23	25	human	human	JJ
cord-321013-8pkrg0mx	23	26	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	23	27	(	(	-LRB-
cord-321013-8pkrg0mx	23	28	SARS)-N	SARS)-N	NNP
cord-321013-8pkrg0mx	23	29	to	to	IN
cord-321013-8pkrg0mx	23	30	aa	aa	NNP
cord-321013-8pkrg0mx	23	31	45	45	CD
cord-321013-8pkrg0mx	23	32	-	-	SYM
cord-321013-8pkrg0mx	23	33	181	181	CD
cord-321013-8pkrg0mx	23	34	[	[	-LRB-
cord-321013-8pkrg0mx	23	35	16	16	CD
cord-321013-8pkrg0mx	23	36	]	]	-RRB-
cord-321013-8pkrg0mx	23	37	,	,	,
cord-321013-8pkrg0mx	23	38	and	and	CC
cord-321013-8pkrg0mx	23	39	for	for	IN
cord-321013-8pkrg0mx	23	40	Mouse	Mouse	NNP
cord-321013-8pkrg0mx	23	41	hepatitis	hepatitis	NNP
cord-321013-8pkrg0mx	23	42	Virus	Virus	NNP
cord-321013-8pkrg0mx	23	43	(	(	-LRB-
cord-321013-8pkrg0mx	23	44	MHV)-N	MHV)-N	NNP
cord-321013-8pkrg0mx	23	45	to	to	IN
cord-321013-8pkrg0mx	23	46	aa	aa	NNP
cord-321013-8pkrg0mx	23	47	[	[	-LRB-
cord-321013-8pkrg0mx	23	48	18	18	CD
cord-321013-8pkrg0mx	23	49	]	]	-RRB-
cord-321013-8pkrg0mx	23	50	.	.	.
cord-321013-8pkrg0mx	24	1	The	the	DT
cord-321013-8pkrg0mx	24	2	N	N	NNP
cord-321013-8pkrg0mx	24	3	-	-	HYPH
cord-321013-8pkrg0mx	24	4	termini	termini	NNP
cord-321013-8pkrg0mx	24	5	of	of	IN
cord-321013-8pkrg0mx	24	6	these	these	DT
cord-321013-8pkrg0mx	24	7	three	three	CD
cord-321013-8pkrg0mx	24	8	CoVs	cov	NNS
cord-321013-8pkrg0mx	24	9	have	have	VBP
cord-321013-8pkrg0mx	24	10	been	be	VBN
cord-321013-8pkrg0mx	24	11	found	find	VBN
cord-321013-8pkrg0mx	24	12	to	to	TO
cord-321013-8pkrg0mx	24	13	associate	associate	VB
cord-321013-8pkrg0mx	24	14	with	with	IN
cord-321013-8pkrg0mx	24	15	the	the	DT
cord-321013-8pkrg0mx	24	16	3	3	CD
cord-321013-8pkrg0mx	24	17	'	'	NN
cord-321013-8pkrg0mx	24	18	end	end	NN
cord-321013-8pkrg0mx	24	19	of	of	IN
cord-321013-8pkrg0mx	24	20	the	the	DT
cord-321013-8pkrg0mx	24	21	viral	viral	JJ
cord-321013-8pkrg0mx	24	22	RNA	RNA	NNP
cord-321013-8pkrg0mx	24	23	genome	genome	NN
cord-321013-8pkrg0mx	24	24	,	,	,
cord-321013-8pkrg0mx	24	25	possibly	possibly	RB
cord-321013-8pkrg0mx	24	26	through	through	IN
cord-321013-8pkrg0mx	24	27	electrostatic	electrostatic	JJ
cord-321013-8pkrg0mx	24	28	interactions	interaction	NNS
cord-321013-8pkrg0mx	24	29	[	[	-LRB-
cord-321013-8pkrg0mx	24	30	21	21	CD
cord-321013-8pkrg0mx	24	31	,	,	,
cord-321013-8pkrg0mx	24	32	22	22	CD
cord-321013-8pkrg0mx	24	33	]	]	-RRB-
cord-321013-8pkrg0mx	24	34	.	.	.
cord-321013-8pkrg0mx	25	1	There	there	EX
cord-321013-8pkrg0mx	25	2	are	be	VBP
cord-321013-8pkrg0mx	25	3	several	several	JJ
cord-321013-8pkrg0mx	25	4	common	common	JJ
cord-321013-8pkrg0mx	25	5	characteristics	characteristic	NNS
cord-321013-8pkrg0mx	25	6	of	of	IN
cord-321013-8pkrg0mx	25	7	CoV	CoV	NNP
cord-321013-8pkrg0mx	25	8	N	n	CD
cord-321013-8pkrg0mx	25	9	protein	protein	NN
cord-321013-8pkrg0mx	25	10	NTDs	ntd	NNS
cord-321013-8pkrg0mx	25	11	,	,	,
cord-321013-8pkrg0mx	25	12	including	include	VBG
cord-321013-8pkrg0mx	25	13	predicted	predict	VBN
cord-321013-8pkrg0mx	25	14	secondary	secondary	JJ
cord-321013-8pkrg0mx	25	15	structures	structure	NNS
cord-321013-8pkrg0mx	25	16	such	such	JJ
cord-321013-8pkrg0mx	25	17	as	as	IN
cord-321013-8pkrg0mx	25	18	a	a	DT
cord-321013-8pkrg0mx	25	19	central	central	JJ
cord-321013-8pkrg0mx	25	20	β	β	NN
cord-321013-8pkrg0mx	25	21	-	-	HYPH
cord-321013-8pkrg0mx	25	22	sheet	sheet	NN
cord-321013-8pkrg0mx	25	23	platform	platform	NN
cord-321013-8pkrg0mx	25	24	flanked	flank	VBN
cord-321013-8pkrg0mx	25	25	by	by	IN
cord-321013-8pkrg0mx	25	26	α	α	NN
cord-321013-8pkrg0mx	25	27	-	-	HYPH
cord-321013-8pkrg0mx	25	28	helices	helix	NNS
cord-321013-8pkrg0mx	25	29	[	[	-LRB-
cord-321013-8pkrg0mx	25	30	20	20	CD
cord-321013-8pkrg0mx	25	31	]	]	-RRB-
cord-321013-8pkrg0mx	25	32	,	,	,
cord-321013-8pkrg0mx	25	33	with	with	IN
cord-321013-8pkrg0mx	25	34	a	a	DT
cord-321013-8pkrg0mx	25	35	basic	basic	JJ
cord-321013-8pkrg0mx	25	36	RNA	RNA	NNP
cord-321013-8pkrg0mx	25	37	binding	binding	NN
cord-321013-8pkrg0mx	25	38	groove	groove	NN
cord-321013-8pkrg0mx	25	39	along	along	IN
cord-321013-8pkrg0mx	25	40	the	the	DT
cord-321013-8pkrg0mx	25	41	β	β	NN
cord-321013-8pkrg0mx	25	42	-	-	HYPH
cord-321013-8pkrg0mx	25	43	platform	platform	NN
cord-321013-8pkrg0mx	25	44	and	and	CC
cord-321013-8pkrg0mx	25	45	an	an	DT
cord-321013-8pkrg0mx	25	46	extended	extended	JJ
cord-321013-8pkrg0mx	25	47	β	β	NN
cord-321013-8pkrg0mx	25	48	-	-	HYPH
cord-321013-8pkrg0mx	25	49	hairpin	hairpin	NNP
cord-321013-8pkrg0mx	25	50	.	.	.
cord-321013-8pkrg0mx	26	1	The	the	DT
cord-321013-8pkrg0mx	26	2	NTD	NTD	NNP
cord-321013-8pkrg0mx	26	3	is	be	VBZ
cord-321013-8pkrg0mx	26	4	enriched	enrich	VBN
cord-321013-8pkrg0mx	26	5	in	in	IN
cord-321013-8pkrg0mx	26	6	aromatic	aromatic	JJ
cord-321013-8pkrg0mx	26	7	and	and	CC
cord-321013-8pkrg0mx	26	8	basic	basic	JJ
cord-321013-8pkrg0mx	26	9	residues	residue	NNS
cord-321013-8pkrg0mx	26	10	and	and	CC
cord-321013-8pkrg0mx	26	11	the	the	DT
cord-321013-8pkrg0mx	26	12	folded	fold	VBN
cord-321013-8pkrg0mx	26	13	shape	shape	NN
cord-321013-8pkrg0mx	26	14	resembles	resemble	VBZ
cord-321013-8pkrg0mx	26	15	a	a	DT
cord-321013-8pkrg0mx	26	16	hand	hand	NN
cord-321013-8pkrg0mx	26	17	with	with	IN
cord-321013-8pkrg0mx	26	18	basic	basic	JJ
cord-321013-8pkrg0mx	26	19	fingers	finger	NNS
cord-321013-8pkrg0mx	26	20	that	that	WDT
cord-321013-8pkrg0mx	26	21	extend	extend	VBP
cord-321013-8pkrg0mx	26	22	far	far	RB
cord-321013-8pkrg0mx	26	23	beyond	beyond	IN
cord-321013-8pkrg0mx	26	24	the	the	DT
cord-321013-8pkrg0mx	26	25	protein	protein	NN
cord-321013-8pkrg0mx	26	26	core	core	NN
cord-321013-8pkrg0mx	26	27	,	,	,
cord-321013-8pkrg0mx	26	28	a	a	DT
cord-321013-8pkrg0mx	26	29	hydrophobic	hydrophobic	JJ
cord-321013-8pkrg0mx	26	30	palm	palm	NN
cord-321013-8pkrg0mx	26	31	,	,	,
cord-321013-8pkrg0mx	26	32	and	and	CC
cord-321013-8pkrg0mx	26	33	an	an	DT
cord-321013-8pkrg0mx	26	34	acidic	acidic	JJ
cord-321013-8pkrg0mx	26	35	-wrist‖	-wrist‖	:
cord-321013-8pkrg0mx	26	36	[	[	-LRB-
cord-321013-8pkrg0mx	26	37	21	21	CD
cord-321013-8pkrg0mx	26	38	]	]	-RRB-
cord-321013-8pkrg0mx	26	39	.	.	.
cord-321013-8pkrg0mx	27	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	27	2	has	have	VBZ
cord-321013-8pkrg0mx	27	3	been	be	VBN
cord-321013-8pkrg0mx	27	4	proposed	propose	VBN
cord-321013-8pkrg0mx	27	5	that	that	IN
cord-321013-8pkrg0mx	27	6	the	the	DT
cord-321013-8pkrg0mx	27	7	flexible	flexible	JJ
cord-321013-8pkrg0mx	27	8	,	,	,
cord-321013-8pkrg0mx	27	9	positively	positively	RB
cord-321013-8pkrg0mx	27	10	charged	charge	VBN
cord-321013-8pkrg0mx	27	11	finger	finger	NN
cord-321013-8pkrg0mx	27	12	-	-	HYPH
cord-321013-8pkrg0mx	27	13	like	like	JJ
cord-321013-8pkrg0mx	27	14	β	β	NN
cord-321013-8pkrg0mx	27	15	-	-	HYPH
cord-321013-8pkrg0mx	27	16	hairpin	hairpin	NN
cord-321013-8pkrg0mx	27	17	extension	extension	NN
cord-321013-8pkrg0mx	27	18	in	in	IN
cord-321013-8pkrg0mx	27	19	the	the	DT
cord-321013-8pkrg0mx	27	20	NTD	NTD	NNP
cord-321013-8pkrg0mx	27	21	of	of	IN
cord-321013-8pkrg0mx	27	22	both	both	CC
cord-321013-8pkrg0mx	27	23	IBV	IBV	NNP
cord-321013-8pkrg0mx	27	24	and	and	CC
cord-321013-8pkrg0mx	27	25	SARS	SARS	NNP
cord-321013-8pkrg0mx	27	26	-	-	HYPH
cord-321013-8pkrg0mx	27	27	CoV	CoV	NNP
cord-321013-8pkrg0mx	27	28	N	n	CD
cord-321013-8pkrg0mx	28	1	protein	protein	NN
cord-321013-8pkrg0mx	28	2	is	be	VBZ
cord-321013-8pkrg0mx	28	3	able	able	JJ
cord-321013-8pkrg0mx	28	4	to	to	TO
cord-321013-8pkrg0mx	28	5	grasp	grasp	VB
cord-321013-8pkrg0mx	28	6	RNA	RNA	NNP
cord-321013-8pkrg0mx	28	7	by	by	IN
cord-321013-8pkrg0mx	28	8	neutralizing	neutralize	VBG
cord-321013-8pkrg0mx	28	9	its	-PRON-	PRP$
cord-321013-8pkrg0mx	28	10	phosphate	phosphate	NN
cord-321013-8pkrg0mx	28	11	groups	group	NNS
cord-321013-8pkrg0mx	28	12	,	,	,
cord-321013-8pkrg0mx	28	13	while	while	IN
cord-321013-8pkrg0mx	28	14	the	the	DT
cord-321013-8pkrg0mx	28	15	base	base	NN
cord-321013-8pkrg0mx	28	16	moieties	moiety	NNS
cord-321013-8pkrg0mx	28	17	can	can	MD
cord-321013-8pkrg0mx	28	18	make	make	VB
cord-321013-8pkrg0mx	28	19	contact	contact	NN
cord-321013-8pkrg0mx	28	20	with	with	IN
cord-321013-8pkrg0mx	28	21	exposed	expose	VBN
cord-321013-8pkrg0mx	28	22	aromatic	aromatic	JJ
cord-321013-8pkrg0mx	28	23	residues	residue	NNS
cord-321013-8pkrg0mx	28	24	from	from	IN
cord-321013-8pkrg0mx	28	25	the	the	DT
cord-321013-8pkrg0mx	28	26	hydrophobic	hydrophobic	JJ
cord-321013-8pkrg0mx	28	27	palm	palm	NN
cord-321013-8pkrg0mx	28	28	[	[	-LRB-
cord-321013-8pkrg0mx	28	29	16	16	CD
cord-321013-8pkrg0mx	28	30	,	,	,
cord-321013-8pkrg0mx	28	31	21	21	CD
cord-321013-8pkrg0mx	28	32	]	]	-RRB-
cord-321013-8pkrg0mx	28	33	.	.	.
cord-321013-8pkrg0mx	29	1	More	more	RBR
cord-321013-8pkrg0mx	29	2	precise	precise	JJ
cord-321013-8pkrg0mx	29	3	mapping	mapping	NN
cord-321013-8pkrg0mx	29	4	of	of	IN
cord-321013-8pkrg0mx	29	5	the	the	DT
cord-321013-8pkrg0mx	29	6	RNA	RNA	NNP
cord-321013-8pkrg0mx	29	7	-	-	HYPH
cord-321013-8pkrg0mx	29	8	binding	bind	VBG
cord-321013-8pkrg0mx	29	9	site	site	NN
cord-321013-8pkrg0mx	29	10	locations	location	NNS
cord-321013-8pkrg0mx	29	11	has	have	VBZ
cord-321013-8pkrg0mx	29	12	been	be	VBN
cord-321013-8pkrg0mx	29	13	determined	determine	VBN
cord-321013-8pkrg0mx	29	14	for	for	IN
cord-321013-8pkrg0mx	29	15	SARS	SARS	NNP
cord-321013-8pkrg0mx	29	16	-	-	:
cord-321013-8pkrg0mx	29	17	and	and	CC
cord-321013-8pkrg0mx	29	18	IBV	IBV	NNP
cord-321013-8pkrg0mx	29	19	-	-	HYPH
cord-321013-8pkrg0mx	29	20	N	N	NNP
cord-321013-8pkrg0mx	29	21	protein	protein	NN
cord-321013-8pkrg0mx	29	22	.	.	.
cord-321013-8pkrg0mx	30	1	Within	within	IN
cord-321013-8pkrg0mx	30	2	the	the	DT
cord-321013-8pkrg0mx	30	3	NTD	NTD	NNP
cord-321013-8pkrg0mx	30	4	of	of	IN
cord-321013-8pkrg0mx	30	5	SARS	SARS	NNP
cord-321013-8pkrg0mx	30	6	-	-	HYPH
cord-321013-8pkrg0mx	30	7	CoV	CoV	NNP
cord-321013-8pkrg0mx	30	8	-	-	HYPH
cord-321013-8pkrg0mx	30	9	N	N	NNP
cord-321013-8pkrg0mx	30	10	,	,	,
cord-321013-8pkrg0mx	30	11	positively	positively	RB
cord-321013-8pkrg0mx	30	12	charged	charge	VBD
cord-321013-8pkrg0mx	30	13	lysine	lysine	NN
cord-321013-8pkrg0mx	30	14	and	and	CC
cord-321013-8pkrg0mx	30	15	arginine	arginine	NN
cord-321013-8pkrg0mx	30	16	residues	residue	NNS
cord-321013-8pkrg0mx	30	17	have	have	VBP
cord-321013-8pkrg0mx	30	18	been	be	VBN
cord-321013-8pkrg0mx	30	19	proposed	propose	VBN
cord-321013-8pkrg0mx	30	20	to	to	TO
cord-321013-8pkrg0mx	30	21	bind	bind	VB
cord-321013-8pkrg0mx	30	22	a	a	DT
cord-321013-8pkrg0mx	30	23	32	32	CD
cord-321013-8pkrg0mx	30	24	nucleotide	nucleotide	JJ
cord-321013-8pkrg0mx	30	25	stem	stem	NN
cord-321013-8pkrg0mx	30	26	-	-	HYPH
cord-321013-8pkrg0mx	30	27	loop	loop	NN
cord-321013-8pkrg0mx	30	28	structure	structure	NN
cord-321013-8pkrg0mx	30	29	located	locate	VBN
cord-321013-8pkrg0mx	30	30	at	at	IN
cord-321013-8pkrg0mx	30	31	the	the	DT
cord-321013-8pkrg0mx	30	32	3	3	CD
cord-321013-8pkrg0mx	30	33	'	'	NN
cord-321013-8pkrg0mx	30	34	end	end	NN
cord-321013-8pkrg0mx	30	35	of	of	IN
cord-321013-8pkrg0mx	30	36	the	the	DT
cord-321013-8pkrg0mx	30	37	SARS	SARS	NNP
cord-321013-8pkrg0mx	30	38	-	-	HYPH
cord-321013-8pkrg0mx	30	39	CoV	CoV	NNP
cord-321013-8pkrg0mx	30	40	RNA	RNA	NNP
cord-321013-8pkrg0mx	30	41	genome	genome	NN
cord-321013-8pkrg0mx	30	42	[	[	-LRB-
cord-321013-8pkrg0mx	30	43	16	16	CD
cord-321013-8pkrg0mx	30	44	]	]	-RRB-
cord-321013-8pkrg0mx	30	45	.	.	.
cord-321013-8pkrg0mx	31	1	Site	site	NN
cord-321013-8pkrg0mx	31	2	-	-	HYPH
cord-321013-8pkrg0mx	31	3	directed	direct	VBN
cord-321013-8pkrg0mx	31	4	mutagenesis	mutagenesis	NN
cord-321013-8pkrg0mx	31	5	studies	study	NNS
cord-321013-8pkrg0mx	31	6	on	on	IN
cord-321013-8pkrg0mx	31	7	IBV	IBV	NNP
cord-321013-8pkrg0mx	31	8	-	-	HYPH
cord-321013-8pkrg0mx	31	9	N	N	NNP
cord-321013-8pkrg0mx	31	10	have	have	VBP
cord-321013-8pkrg0mx	31	11	identified	identify	VBN
cord-321013-8pkrg0mx	31	12	two	two	CD
cord-321013-8pkrg0mx	31	13	residues	residue	NNS
cord-321013-8pkrg0mx	31	14	that	that	WDT
cord-321013-8pkrg0mx	31	15	are	be	VBP
cord-321013-8pkrg0mx	31	16	critical	critical	JJ
cord-321013-8pkrg0mx	31	17	for	for	IN
cord-321013-8pkrg0mx	31	18	RNA	RNA	NNP
cord-321013-8pkrg0mx	31	19	binding	binding	NN
cord-321013-8pkrg0mx	31	20	;	;	:
cord-321013-8pkrg0mx	31	21	namely	namely	RB
cord-321013-8pkrg0mx	31	22	Tyr-94	Tyr-94	NNP
cord-321013-8pkrg0mx	31	23	and	and	CC
cord-321013-8pkrg0mx	31	24	Arg-76	Arg-76	NNP
cord-321013-8pkrg0mx	31	25	[	[	-LRB-
cord-321013-8pkrg0mx	31	26	23	23	CD
cord-321013-8pkrg0mx	31	27	]	]	-RRB-
cord-321013-8pkrg0mx	31	28	.	.	.
cord-321013-8pkrg0mx	32	1	Tyr-94	Tyr-94	NNP
cord-321013-8pkrg0mx	32	2	is	be	VBZ
cord-321013-8pkrg0mx	32	3	located	locate	VBN
cord-321013-8pkrg0mx	32	4	in	in	IN
cord-321013-8pkrg0mx	32	5	strand	strand	NN
cord-321013-8pkrg0mx	32	6	β3	β3	NN
cord-321013-8pkrg0mx	32	7	of	of	IN
cord-321013-8pkrg0mx	32	8	the	the	DT
cord-321013-8pkrg0mx	32	9	four	four	CD
cord-321013-8pkrg0mx	32	10	-	-	HYPH
cord-321013-8pkrg0mx	32	11	stranded	strand	VBN
cord-321013-8pkrg0mx	32	12	anti	anti	JJ
cord-321013-8pkrg0mx	32	13	-	-	JJ
cord-321013-8pkrg0mx	32	14	parallel	parallel	JJ
cord-321013-8pkrg0mx	32	15	β	β	NN
cord-321013-8pkrg0mx	32	16	sheet	sheet	NN
cord-321013-8pkrg0mx	32	17	;	;	:
cord-321013-8pkrg0mx	32	18	Arg-76	Arg-76	NNP
cord-321013-8pkrg0mx	32	19	is	be	VBZ
cord-321013-8pkrg0mx	32	20	located	locate	VBN
cord-321013-8pkrg0mx	32	21	in	in	IN
cord-321013-8pkrg0mx	32	22	the	the	DT
cord-321013-8pkrg0mx	32	23	immediate	immediate	JJ
cord-321013-8pkrg0mx	32	24	vicinity	vicinity	NN
cord-321013-8pkrg0mx	32	25	of	of	IN
cord-321013-8pkrg0mx	32	26	Tyr-94	Tyr-94	NNP
cord-321013-8pkrg0mx	32	27	,	,	,
cord-321013-8pkrg0mx	32	28	at	at	IN
cord-321013-8pkrg0mx	32	29	the	the	DT
cord-321013-8pkrg0mx	32	30	base	base	NN
cord-321013-8pkrg0mx	32	31	of	of	IN
cord-321013-8pkrg0mx	32	32	the	the	DT
cord-321013-8pkrg0mx	32	33	extended	extended	JJ
cord-321013-8pkrg0mx	32	34	flexible	flexible	JJ
cord-321013-8pkrg0mx	32	35	hairpin	hairpin	NN
cord-321013-8pkrg0mx	32	36	loop	loop	NN
cord-321013-8pkrg0mx	32	37	[	[	-LRB-
cord-321013-8pkrg0mx	32	38	23	23	CD
cord-321013-8pkrg0mx	32	39	]	]	-RRB-
cord-321013-8pkrg0mx	32	40	.	.	.
cord-321013-8pkrg0mx	33	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	33	2	is	be	VBZ
cord-321013-8pkrg0mx	33	3	however	however	RB
cord-321013-8pkrg0mx	33	4	likely	likely	JJ
cord-321013-8pkrg0mx	33	5	that	that	IN
cord-321013-8pkrg0mx	33	6	,	,	,
cord-321013-8pkrg0mx	33	7	since	since	IN
cord-321013-8pkrg0mx	33	8	no	no	DT
cord-321013-8pkrg0mx	33	9	single	single	JJ
cord-321013-8pkrg0mx	33	10	mutation	mutation	NN
cord-321013-8pkrg0mx	33	11	totally	totally	RB
cord-321013-8pkrg0mx	33	12	disrupts	disrupt	VBZ
cord-321013-8pkrg0mx	33	13	RNA	rna	NN
cord-321013-8pkrg0mx	33	14	binding	binding	NN
cord-321013-8pkrg0mx	33	15	,	,	,
cord-321013-8pkrg0mx	33	16	other	other	JJ
cord-321013-8pkrg0mx	33	17	aromatic	aromatic	JJ
cord-321013-8pkrg0mx	33	18	/	/	SYM
cord-321013-8pkrg0mx	33	19	basic	basic	JJ
cord-321013-8pkrg0mx	33	20	residues	residue	NNS
cord-321013-8pkrg0mx	33	21	at	at	IN
cord-321013-8pkrg0mx	33	22	the	the	DT
cord-321013-8pkrg0mx	33	23	surface	surface	NN
cord-321013-8pkrg0mx	33	24	of	of	IN
cord-321013-8pkrg0mx	33	25	the	the	DT
cord-321013-8pkrg0mx	33	26	NTD	NTD	NNP
cord-321013-8pkrg0mx	33	27	contribute	contribute	VBP
cord-321013-8pkrg0mx	33	28	to	to	IN
cord-321013-8pkrg0mx	33	29	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	33	30	acid	acid	NN
cord-321013-8pkrg0mx	33	31	binding	bind	VBG
cord-321013-8pkrg0mx	33	32	by	by	IN
cord-321013-8pkrg0mx	33	33	creating	create	VBG
cord-321013-8pkrg0mx	33	34	a	a	DT
cord-321013-8pkrg0mx	33	35	broad	broad	JJ
cord-321013-8pkrg0mx	33	36	surface	surface	NN
cord-321013-8pkrg0mx	33	37	that	that	WDT
cord-321013-8pkrg0mx	33	38	comes	come	VBZ
cord-321013-8pkrg0mx	33	39	into	into	IN
cord-321013-8pkrg0mx	33	40	contact	contact	NN
cord-321013-8pkrg0mx	33	41	with	with	IN
cord-321013-8pkrg0mx	33	42	the	the	DT
cord-321013-8pkrg0mx	33	43	viral	viral	JJ
cord-321013-8pkrg0mx	33	44	genomic	genomic	JJ
cord-321013-8pkrg0mx	33	45	RNA	RNA	NNP
cord-321013-8pkrg0mx	33	46	[	[	-LRB-
cord-321013-8pkrg0mx	33	47	23	23	CD
cord-321013-8pkrg0mx	33	48	]	]	-RRB-
cord-321013-8pkrg0mx	33	49	.	.	.
cord-321013-8pkrg0mx	34	1	The	the	DT
cord-321013-8pkrg0mx	34	2	NTD	NTD	NNP
cord-321013-8pkrg0mx	34	3	possesses	possess	VBZ
cord-321013-8pkrg0mx	34	4	some	some	DT
cord-321013-8pkrg0mx	34	5	features	feature	NNS
cord-321013-8pkrg0mx	34	6	similar	similar	JJ
cord-321013-8pkrg0mx	34	7	to	to	IN
cord-321013-8pkrg0mx	34	8	those	those	DT
cord-321013-8pkrg0mx	34	9	of	of	IN
cord-321013-8pkrg0mx	34	10	other	other	JJ
cord-321013-8pkrg0mx	34	11	RNA	RNA	NNP
cord-321013-8pkrg0mx	34	12	-	-	HYPH
cord-321013-8pkrg0mx	34	13	binding	bind	VBG
cord-321013-8pkrg0mx	34	14	proteins	protein	NNS
cord-321013-8pkrg0mx	34	15	that	that	WDT
cord-321013-8pkrg0mx	34	16	form	form	VBP
cord-321013-8pkrg0mx	34	17	a	a	DT
cord-321013-8pkrg0mx	34	18	RNP	rnp	NN
cord-321013-8pkrg0mx	34	19	.	.	.
cord-321013-8pkrg0mx	35	1	For	for	IN
cord-321013-8pkrg0mx	35	2	example	example	NN
cord-321013-8pkrg0mx	35	3	,	,	,
cord-321013-8pkrg0mx	35	4	the	the	DT
cord-321013-8pkrg0mx	35	5	U1A	U1A	NNP
cord-321013-8pkrg0mx	35	6	spliceosomal	spliceosomal	NNP
cord-321013-8pkrg0mx	35	7	protein	protein	NN
cord-321013-8pkrg0mx	35	8	[	[	-LRB-
cord-321013-8pkrg0mx	35	9	24	24	CD
cord-321013-8pkrg0mx	35	10	]	]	-RRB-
cord-321013-8pkrg0mx	35	11	and	and	CC
cord-321013-8pkrg0mx	35	12	the	the	DT
cord-321013-8pkrg0mx	35	13	coat	coat	NN
cord-321013-8pkrg0mx	35	14	protein	protein	NN
cord-321013-8pkrg0mx	35	15	of	of	IN
cord-321013-8pkrg0mx	35	16	MS2	MS2	NNP
cord-321013-8pkrg0mx	35	17	bacteriophage	bacteriophage	NN
cord-321013-8pkrg0mx	35	18	[	[	-LRB-
cord-321013-8pkrg0mx	35	19	25	25	CD
cord-321013-8pkrg0mx	35	20	]	]	-RRB-
cord-321013-8pkrg0mx	35	21	bind	bind	VBP
cord-321013-8pkrg0mx	35	22	viral	viral	JJ
cord-321013-8pkrg0mx	35	23	RNA	rna	NN
cord-321013-8pkrg0mx	35	24	with	with	IN
cord-321013-8pkrg0mx	35	25	residues	residue	NNS
cord-321013-8pkrg0mx	35	26	arising	arise	VBG
cord-321013-8pkrg0mx	35	27	from	from	IN
cord-321013-8pkrg0mx	35	28	the	the	DT
cord-321013-8pkrg0mx	35	29	surface	surface	NN
cord-321013-8pkrg0mx	35	30	of	of	IN
cord-321013-8pkrg0mx	35	31	a	a	DT
cord-321013-8pkrg0mx	35	32	four	four	CD
cord-321013-8pkrg0mx	35	33	-	-	HYPH
cord-321013-8pkrg0mx	35	34	stranded	strand	VBN
cord-321013-8pkrg0mx	35	35	anti	anti	JJ
cord-321013-8pkrg0mx	35	36	-	-	JJ
cord-321013-8pkrg0mx	35	37	parallel	parallel	JJ
cord-321013-8pkrg0mx	35	38	β	β	NN
cord-321013-8pkrg0mx	35	39	sheet	sheet	NN
cord-321013-8pkrg0mx	35	40	.	.	.
cord-321013-8pkrg0mx	36	1	Seemingly	seemingly	RB
cord-321013-8pkrg0mx	36	2	,	,	,
cord-321013-8pkrg0mx	36	3	strands	strand	NNS
cord-321013-8pkrg0mx	36	4	β2	β2	NN
cord-321013-8pkrg0mx	36	5	,	,	,
cord-321013-8pkrg0mx	36	6	β3	β3	NNP
cord-321013-8pkrg0mx	36	7	,	,	,
cord-321013-8pkrg0mx	36	8	and	and	CC
cord-321013-8pkrg0mx	36	9	the	the	DT
cord-321013-8pkrg0mx	36	10	flexible	flexible	JJ
cord-321013-8pkrg0mx	36	11	β	β	NN
cord-321013-8pkrg0mx	36	12	-	-	HYPH
cord-321013-8pkrg0mx	36	13	hairpin	hairpin	NN
cord-321013-8pkrg0mx	36	14	from	from	IN
cord-321013-8pkrg0mx	36	15	the	the	DT
cord-321013-8pkrg0mx	36	16	IBV	IBV	NNP
cord-321013-8pkrg0mx	36	17	N	N	NNP
cord-321013-8pkrg0mx	36	18	protein	protein	NN
cord-321013-8pkrg0mx	36	19	could	could	MD
cord-321013-8pkrg0mx	36	20	fulfill	fulfill	VB
cord-321013-8pkrg0mx	36	21	a	a	DT
cord-321013-8pkrg0mx	36	22	comparable	comparable	JJ
cord-321013-8pkrg0mx	36	23	role	role	NN
cord-321013-8pkrg0mx	36	24	by	by	IN
cord-321013-8pkrg0mx	36	25	interacting	interact	VBG
cord-321013-8pkrg0mx	36	26	with	with	IN
cord-321013-8pkrg0mx	36	27	phosphate	phosphate	NN
cord-321013-8pkrg0mx	36	28	groups	group	NNS
cord-321013-8pkrg0mx	36	29	on	on	IN
cord-321013-8pkrg0mx	36	30	the	the	DT
cord-321013-8pkrg0mx	36	31	viral	viral	JJ
cord-321013-8pkrg0mx	36	32	RNA	RNA	NNP
cord-321013-8pkrg0mx	36	33	[	[	-LRB-
cord-321013-8pkrg0mx	36	34	23	23	CD
cord-321013-8pkrg0mx	36	35	]	]	-RRB-
cord-321013-8pkrg0mx	36	36	.	.	.
cord-321013-8pkrg0mx	37	1	The	the	DT
cord-321013-8pkrg0mx	37	2	Arg-76	Arg-76	NNP
cord-321013-8pkrg0mx	37	3	and	and	CC
cord-321013-8pkrg0mx	37	4	Tyr-94	Tyr-94	NNP
cord-321013-8pkrg0mx	37	5	residues	residue	NNS
cord-321013-8pkrg0mx	37	6	in	in	IN
cord-321013-8pkrg0mx	37	7	the	the	DT
cord-321013-8pkrg0mx	37	8	IBV	IBV	NNP
cord-321013-8pkrg0mx	37	9	N	N	NNP
cord-321013-8pkrg0mx	37	10	protein	protein	NN
cord-321013-8pkrg0mx	37	11	are	be	VBP
cord-321013-8pkrg0mx	37	12	well	well	RB
cord-321013-8pkrg0mx	37	13	conserved	conserve	VBN
cord-321013-8pkrg0mx	37	14	across	across	IN
cord-321013-8pkrg0mx	37	15	the	the	DT
cord-321013-8pkrg0mx	37	16	whole	whole	JJ
cord-321013-8pkrg0mx	37	17	CoV	cov	NN
cord-321013-8pkrg0mx	37	18	family	family	NN
cord-321013-8pkrg0mx	37	19	,	,	,
cord-321013-8pkrg0mx	37	20	and	and	CC
cord-321013-8pkrg0mx	37	21	may	may	MD
cord-321013-8pkrg0mx	37	22	structurally	structurally	RB
cord-321013-8pkrg0mx	37	23	correspond	correspond	VB
cord-321013-8pkrg0mx	37	24	to	to	IN
cord-321013-8pkrg0mx	37	25	the	the	DT
cord-321013-8pkrg0mx	37	26	Arg-94	Arg-94	NNP
cord-321013-8pkrg0mx	37	27	and	and	CC
cord-321013-8pkrg0mx	37	28	Tyr-122	Tyr-122	NNP
cord-321013-8pkrg0mx	37	29	residues	residue	NNS
cord-321013-8pkrg0mx	37	30	in	in	IN
cord-321013-8pkrg0mx	37	31	the	the	DT
cord-321013-8pkrg0mx	37	32	SARS	SARS	NNP
cord-321013-8pkrg0mx	37	33	-	-	HYPH
cord-321013-8pkrg0mx	37	34	CoV	CoV	NNP
cord-321013-8pkrg0mx	37	35	N	n	CD
cord-321013-8pkrg0mx	37	36	protein	protein	NN
cord-321013-8pkrg0mx	37	37	[	[	-LRB-
cord-321013-8pkrg0mx	37	38	23	23	CD
cord-321013-8pkrg0mx	37	39	]	]	-RRB-
cord-321013-8pkrg0mx	37	40	,	,	,
cord-321013-8pkrg0mx	37	41	meaning	mean	VBG
cord-321013-8pkrg0mx	37	42	that	that	IN
cord-321013-8pkrg0mx	37	43	Arg-94	Arg-94	NNP
cord-321013-8pkrg0mx	37	44	and	and	CC
cord-321013-8pkrg0mx	37	45	Tyr-122	Tyr-122	NNP
cord-321013-8pkrg0mx	37	46	may	may	MD
cord-321013-8pkrg0mx	37	47	therefore	therefore	RB
cord-321013-8pkrg0mx	37	48	be	be	VB
cord-321013-8pkrg0mx	37	49	critical	critical	JJ
cord-321013-8pkrg0mx	37	50	for	for	IN
cord-321013-8pkrg0mx	37	51	SARS	SARS	NNP
cord-321013-8pkrg0mx	37	52	N	N	NNP
cord-321013-8pkrg0mx	37	53	-	-	HYPH
cord-321013-8pkrg0mx	37	54	RNA	RNA	NNP
cord-321013-8pkrg0mx	37	55	binding	binding	NN
cord-321013-8pkrg0mx	37	56	.	.	.
cord-321013-8pkrg0mx	38	1	The	the	DT
cord-321013-8pkrg0mx	38	2	crystal	crystal	JJ
cord-321013-8pkrg0mx	38	3	structure	structure	NN
cord-321013-8pkrg0mx	38	4	of	of	IN
cord-321013-8pkrg0mx	38	5	MHV	MHV	NNP
cord-321013-8pkrg0mx	38	6	N197	N197	NNP
cord-321013-8pkrg0mx	39	1	(	(	-LRB-
cord-321013-8pkrg0mx	39	2	residues	residue	NNS
cord-321013-8pkrg0mx	39	3	60	60	CD
cord-321013-8pkrg0mx	39	4	-	-	SYM
cord-321013-8pkrg0mx	39	5	197	197	CD
cord-321013-8pkrg0mx	39	6	)	)	-RRB-
cord-321013-8pkrg0mx	39	7	adopts	adopt	VBZ
cord-321013-8pkrg0mx	39	8	a	a	DT
cord-321013-8pkrg0mx	39	9	U	u	NN
cord-321013-8pkrg0mx	39	10	-	-	HYPH
cord-321013-8pkrg0mx	39	11	shaped	shape	VBN
cord-321013-8pkrg0mx	39	12	β	β	NN
cord-321013-8pkrg0mx	39	13	-	-	HYPH
cord-321013-8pkrg0mx	39	14	platform	platform	NN
cord-321013-8pkrg0mx	39	15	containing	contain	VBG
cord-321013-8pkrg0mx	39	16	five	five	CD
cord-321013-8pkrg0mx	39	17	short	short	JJ
cord-321013-8pkrg0mx	39	18	β	β	NN
cord-321013-8pkrg0mx	39	19	-	-	HYPH
cord-321013-8pkrg0mx	39	20	strands	strand	NNS
cord-321013-8pkrg0mx	39	21	(	(	-LRB-
cord-321013-8pkrg0mx	39	22	arranged	arrange	VBN
cord-321013-8pkrg0mx	39	23	β4-β2-β3-β1-β5	β4-β2-β3-β1-β5	NNPS
cord-321013-8pkrg0mx	39	24	)	)	-RRB-
cord-321013-8pkrg0mx	39	25	across	across	IN
cord-321013-8pkrg0mx	39	26	the	the	DT
cord-321013-8pkrg0mx	39	27	platform	platform	NN
cord-321013-8pkrg0mx	39	28	with	with	IN
cord-321013-8pkrg0mx	39	29	an	an	DT
cord-321013-8pkrg0mx	39	30	extended	extended	JJ
cord-321013-8pkrg0mx	39	31	β2'-β3	β2'-β3	NN
cord-321013-8pkrg0mx	39	32	'	'	''
cord-321013-8pkrg0mx	39	33	hairpin	hairpin	NN
cord-321013-8pkrg0mx	39	34	similar	similar	JJ
cord-321013-8pkrg0mx	39	35	to	to	IN
cord-321013-8pkrg0mx	39	36	NTDs	ntd	NNS
cord-321013-8pkrg0mx	39	37	from	from	IN
cord-321013-8pkrg0mx	39	38	other	other	JJ
cord-321013-8pkrg0mx	39	39	CoV	cov	NN
cord-321013-8pkrg0mx	39	40	N	n	CD
cord-321013-8pkrg0mx	39	41	proteins	protein	NNS
cord-321013-8pkrg0mx	39	42	[	[	-LRB-
cord-321013-8pkrg0mx	39	43	26	26	CD
cord-321013-8pkrg0mx	39	44	]	]	-RRB-
cord-321013-8pkrg0mx	39	45	.	.	.
cord-321013-8pkrg0mx	40	1	Interestingly	interestingly	RB
cord-321013-8pkrg0mx	40	2	,	,	,
cord-321013-8pkrg0mx	40	3	the	the	DT
cord-321013-8pkrg0mx	40	4	crystal	crystal	NN
cord-321013-8pkrg0mx	40	5	structure	structure	NN
cord-321013-8pkrg0mx	40	6	of	of	IN
cord-321013-8pkrg0mx	40	7	the	the	DT
cord-321013-8pkrg0mx	40	8	MHV	MHV	NNP
cord-321013-8pkrg0mx	40	9	NTD	NTD	NNP
cord-321013-8pkrg0mx	40	10	shares	share	VBZ
cord-321013-8pkrg0mx	40	11	a	a	DT
cord-321013-8pkrg0mx	40	12	similar	similar	JJ
cord-321013-8pkrg0mx	40	13	overall	overall	NN
cord-321013-8pkrg0mx	40	14	and	and	CC
cord-321013-8pkrg0mx	40	15	topology	topology	NN
cord-321013-8pkrg0mx	40	16	structure	structure	NN
cord-321013-8pkrg0mx	40	17	with	with	IN
cord-321013-8pkrg0mx	40	18	that	that	DT
cord-321013-8pkrg0mx	40	19	of	of	IN
cord-321013-8pkrg0mx	40	20	SARS	SARS	NNP
cord-321013-8pkrg0mx	40	21	-	-	HYPH
cord-321013-8pkrg0mx	40	22	CoV	CoV	NNP
cord-321013-8pkrg0mx	40	23	and	and	CC
cord-321013-8pkrg0mx	40	24	IBV	IBV	NNP
cord-321013-8pkrg0mx	40	25	but	but	CC
cord-321013-8pkrg0mx	40	26	varies	vary	VBZ
cord-321013-8pkrg0mx	40	27	in	in	IN
cord-321013-8pkrg0mx	40	28	its	-PRON-	PRP$
cord-321013-8pkrg0mx	40	29	potential	potential	JJ
cord-321013-8pkrg0mx	40	30	surface	surface	NN
cord-321013-8pkrg0mx	40	31	,	,	,
cord-321013-8pkrg0mx	40	32	indicating	indicate	VBG
cord-321013-8pkrg0mx	40	33	a	a	DT
cord-321013-8pkrg0mx	40	34	possible	possible	JJ
cord-321013-8pkrg0mx	40	35	difference	difference	NN
cord-321013-8pkrg0mx	40	36	in	in	IN
cord-321013-8pkrg0mx	40	37	RNA	rna	NN
cord-321013-8pkrg0mx	40	38	-	-	HYPH
cord-321013-8pkrg0mx	40	39	binding	bind	VBG
cord-321013-8pkrg0mx	40	40	module	module	NN
cord-321013-8pkrg0mx	40	41	[	[	-LRB-
cord-321013-8pkrg0mx	40	42	27	27	CD
cord-321013-8pkrg0mx	40	43	]	]	-RRB-
cord-321013-8pkrg0mx	40	44	.	.	.
cord-321013-8pkrg0mx	41	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	41	2	has	have	VBZ
cord-321013-8pkrg0mx	41	3	been	be	VBN
cord-321013-8pkrg0mx	41	4	shown	show	VBN
cord-321013-8pkrg0mx	41	5	that	that	IN
cord-321013-8pkrg0mx	41	6	N219	N219	NNP
cord-321013-8pkrg0mx	41	7	,	,	,
cord-321013-8pkrg0mx	41	8	an	an	DT
cord-321013-8pkrg0mx	41	9	MHV	MHV	NNP
cord-321013-8pkrg0mx	41	10	-	-	HYPH
cord-321013-8pkrg0mx	41	11	A59	A59	NNP
cord-321013-8pkrg0mx	41	12	N	N	NNP
cord-321013-8pkrg0mx	41	13	domain	domain	NN
cord-321013-8pkrg0mx	41	14	protein	protein	NN
cord-321013-8pkrg0mx	41	15	fragment	fragment	NN
cord-321013-8pkrg0mx	41	16	that	that	WDT
cord-321013-8pkrg0mx	41	17	contains	contain	VBZ
cord-321013-8pkrg0mx	41	18	the	the	DT
cord-321013-8pkrg0mx	41	19	folded	fold	VBN
cord-321013-8pkrg0mx	41	20	NTD	NTD	NNP
cord-321013-8pkrg0mx	41	21	and	and	CC
cord-321013-8pkrg0mx	41	22	the	the	DT
cord-321013-8pkrg0mx	41	23	immediately	immediately	RB
cord-321013-8pkrg0mx	41	24	adjacent	adjacent	JJ
cord-321013-8pkrg0mx	41	25	intact	intact	JJ
cord-321013-8pkrg0mx	41	26	linker	linker	NN
cord-321013-8pkrg0mx	41	27	region	region	NN
cord-321013-8pkrg0mx	41	28	(	(	-LRB-
cord-321013-8pkrg0mx	41	29	LKR	LKR	NNP
cord-321013-8pkrg0mx	41	30	;	;	:
cord-321013-8pkrg0mx	41	31	residues	residue	NNS
cord-321013-8pkrg0mx	41	32	60	60	CD
cord-321013-8pkrg0mx	41	33	-	-	SYM
cord-321013-8pkrg0mx	41	34	219	219	CD
cord-321013-8pkrg0mx	41	35	)	)	-RRB-
cord-321013-8pkrg0mx	41	36	,	,	,
cord-321013-8pkrg0mx	41	37	binds	bind	VBZ
cord-321013-8pkrg0mx	41	38	to	to	IN
cord-321013-8pkrg0mx	41	39	the	the	DT
cord-321013-8pkrg0mx	41	40	TRS	TRS	NNP
cord-321013-8pkrg0mx	41	41	in	in	IN
cord-321013-8pkrg0mx	41	42	the	the	DT
cord-321013-8pkrg0mx	41	43	viral	viral	JJ
cord-321013-8pkrg0mx	41	44	genome	genome	NN
cord-321013-8pkrg0mx	41	45	body	body	NN
cord-321013-8pkrg0mx	41	46	(	(	-LRB-
cord-321013-8pkrg0mx	41	47	TRS	TRS	NNP
cord-321013-8pkrg0mx	41	48	-	-	HYPH
cord-321013-8pkrg0mx	41	49	B	B	NNP
cord-321013-8pkrg0mx	41	50	)	)	-RRB-
cord-321013-8pkrg0mx	41	51	and	and	CC
cord-321013-8pkrg0mx	41	52	complementary	complementary	JJ
cord-321013-8pkrg0mx	41	53	TRS	TRS	NNP
cord-321013-8pkrg0mx	41	54	(	(	-LRB-
cord-321013-8pkrg0mx	41	55	cTRS	cTRS	NNP
cord-321013-8pkrg0mx	41	56	)	)	-RRB-
cord-321013-8pkrg0mx	41	57	with	with	IN
cord-321013-8pkrg0mx	41	58	high	high	JJ
cord-321013-8pkrg0mx	41	59	affinity	affinity	NN
cord-321013-8pkrg0mx	41	60	to	to	TO
cord-321013-8pkrg0mx	41	61	form	form	VB
cord-321013-8pkrg0mx	41	62	a	a	DT
cord-321013-8pkrg0mx	41	63	N219-TRS	N219-TRS	NNP
cord-321013-8pkrg0mx	41	64	duplex	duplex	NN
cord-321013-8pkrg0mx	41	65	[	[	-LRB-
cord-321013-8pkrg0mx	41	66	26	26	CD
cord-321013-8pkrg0mx	41	67	]	]	-RRB-
cord-321013-8pkrg0mx	41	68	.	.	.
cord-321013-8pkrg0mx	42	1	MHV	MHV	NNP
cord-321013-8pkrg0mx	42	2	TRS	TRS	NNP
cord-321013-8pkrg0mx	42	3	binds	bind	VBZ
cord-321013-8pkrg0mx	42	4	across	across	IN
cord-321013-8pkrg0mx	42	5	the	the	DT
cord-321013-8pkrg0mx	42	6	β	β	NN
cord-321013-8pkrg0mx	42	7	-	-	HYPH
cord-321013-8pkrg0mx	42	8	platform	platform	NN
cord-321013-8pkrg0mx	42	9	of	of	IN
cord-321013-8pkrg0mx	42	10	NTD	NTD	NNP
cord-321013-8pkrg0mx	42	11	in	in	IN
cord-321013-8pkrg0mx	42	12	a	a	DT
cord-321013-8pkrg0mx	42	13	defined	define	VBN
cord-321013-8pkrg0mx	42	14	orientation	orientation	NN
cord-321013-8pkrg0mx	42	15	,	,	,
cord-321013-8pkrg0mx	42	16	with	with	IN
cord-321013-8pkrg0mx	42	17	the	the	DT
cord-321013-8pkrg0mx	42	18	5'-end	5'-end	CD
cord-321013-8pkrg0mx	42	19	of	of	IN
cord-321013-8pkrg0mx	42	20	TRS	TRS	NNP
cord-321013-8pkrg0mx	42	21	near	near	IN
cord-321013-8pkrg0mx	42	22	β4	β4	NNP
cord-321013-8pkrg0mx	42	23	and	and	CC
cord-321013-8pkrg0mx	42	24	the	the	DT
cord-321013-8pkrg0mx	42	25	3'-end	3'-end	CD
cord-321013-8pkrg0mx	42	26	of	of	IN
cord-321013-8pkrg0mx	42	27	TRS	TRS	NNP
cord-321013-8pkrg0mx	42	28	near	near	IN
cord-321013-8pkrg0mx	42	29	β5	β5	NNP
cord-321013-8pkrg0mx	42	30	;	;	:
cord-321013-8pkrg0mx	42	31	this	this	DT
cord-321013-8pkrg0mx	42	32	N219	N219	VBZ
cord-321013-8pkrg0mx	42	33	binding	bind	VBG
cord-321013-8pkrg0mx	42	34	to	to	IN
cord-321013-8pkrg0mx	42	35	single	single	RB
cord-321013-8pkrg0mx	42	36	-	-	HYPH
cord-321013-8pkrg0mx	42	37	stranded	stranded	JJ
cord-321013-8pkrg0mx	42	38	RNAs	rna	NNS
cord-321013-8pkrg0mx	42	39	-	-	:
cord-321013-8pkrg0mx	42	40	containing	contain	VBG
cord-321013-8pkrg0mx	42	41	the	the	DT
cord-321013-8pkrg0mx	42	42	TRS	TRS	NNP
cord-321013-8pkrg0mx	42	43	or	or	CC
cord-321013-8pkrg0mx	42	44	cTRS	ctrs	NN
cord-321013-8pkrg0mx	42	45	-	-	HYPH
cord-321013-8pkrg0mx	42	46	uses	use	NNS
cord-321013-8pkrg0mx	42	47	base	base	NN
cord-321013-8pkrg0mx	42	48	stacking	stack	VBG
cord-321013-8pkrg0mx	42	49	interactions	interaction	NNS
cord-321013-8pkrg0mx	42	50	between	between	IN
cord-321013-8pkrg0mx	42	51	aromatic	aromatic	JJ
cord-321013-8pkrg0mx	42	52	side	side	NN
cord-321013-8pkrg0mx	42	53	chains	chain	NNS
cord-321013-8pkrg0mx	42	54	on	on	IN
cord-321013-8pkrg0mx	42	55	the	the	DT
cord-321013-8pkrg0mx	42	56	β	β	NN
cord-321013-8pkrg0mx	42	57	-	-	HYPH
cord-321013-8pkrg0mx	42	58	platform	platform	NN
cord-321013-8pkrg0mx	42	59	with	with	IN
cord-321013-8pkrg0mx	42	60	a	a	DT
cord-321013-8pkrg0mx	42	61	triple	triple	JJ
cord-321013-8pkrg0mx	42	62	adenosine	adenosine	NN
cord-321013-8pkrg0mx	42	63	motif	motif	NN
cord-321013-8pkrg0mx	42	64	within	within	IN
cord-321013-8pkrg0mx	42	65	the	the	DT
cord-321013-8pkrg0mx	42	66	TRS	TRS	NNP
cord-321013-8pkrg0mx	43	1	,	,	,
cord-321013-8pkrg0mx	43	2	5'-gAAUCUAAACU-3	5'-gAAUCUAAACU-3	NNP
cord-321013-8pkrg0mx	43	3	'	'	POS
cord-321013-8pkrg0mx	43	4	[	[	-LRB-
cord-321013-8pkrg0mx	43	5	26	26	CD
cord-321013-8pkrg0mx	43	6	]	]	-RRB-
cord-321013-8pkrg0mx	43	7	.	.	.
cord-321013-8pkrg0mx	44	1	Furthermore	furthermore	RB
cord-321013-8pkrg0mx	44	2	,	,	,
cord-321013-8pkrg0mx	44	3	due	due	IN
cord-321013-8pkrg0mx	44	4	to	to	IN
cord-321013-8pkrg0mx	44	5	its	-PRON-	PRP$
cord-321013-8pkrg0mx	44	6	potent	potent	JJ
cord-321013-8pkrg0mx	44	7	helix	helix	NN
cord-321013-8pkrg0mx	44	8	-	-	HYPH
cord-321013-8pkrg0mx	44	9	destabilizing	destabilize	VBG
cord-321013-8pkrg0mx	44	10	activity	activity	NN
cord-321013-8pkrg0mx	44	11	,	,	,
cord-321013-8pkrg0mx	44	12	N219	N219	NNP
cord-321013-8pkrg0mx	44	13	is	be	VBZ
cord-321013-8pkrg0mx	44	14	able	able	JJ
cord-321013-8pkrg0mx	44	15	to	to	TO
cord-321013-8pkrg0mx	44	16	efficiently	efficiently	RB
cord-321013-8pkrg0mx	44	17	melt	melt	VB
cord-321013-8pkrg0mx	44	18	an	an	DT
cord-321013-8pkrg0mx	44	19	RNA	RNA	NNP
cord-321013-8pkrg0mx	44	20	duplex	duplex	NN
cord-321013-8pkrg0mx	44	21	between	between	IN
cord-321013-8pkrg0mx	44	22	the	the	DT
cord-321013-8pkrg0mx	44	23	template	template	NN
cord-321013-8pkrg0mx	44	24	TRS	TRS	NNP
cord-321013-8pkrg0mx	44	25	and	and	CC
cord-321013-8pkrg0mx	44	26	nascent	nascent	JJ
cord-321013-8pkrg0mx	44	27	cTRS	ctrs	NN
cord-321013-8pkrg0mx	44	28	strand	strand	NN
cord-321013-8pkrg0mx	44	29	into	into	IN
cord-321013-8pkrg0mx	44	30	component	component	NN
cord-321013-8pkrg0mx	44	31	single	single	JJ
cord-321013-8pkrg0mx	44	32	strands	strand	NNS
cord-321013-8pkrg0mx	44	33	that	that	WDT
cord-321013-8pkrg0mx	44	34	may	may	MD
cord-321013-8pkrg0mx	44	35	be	be	VB
cord-321013-8pkrg0mx	44	36	transiently	transiently	RB
cord-321013-8pkrg0mx	44	37	formed	form	VBN
cord-321013-8pkrg0mx	44	38	during	during	IN
cord-321013-8pkrg0mx	44	39	discontinuous	discontinuous	JJ
cord-321013-8pkrg0mx	44	40	transcription	transcription	NN
cord-321013-8pkrg0mx	44	41	of	of	IN
cord-321013-8pkrg0mx	44	42	viral	viral	JJ
cord-321013-8pkrg0mx	44	43	sgRNA	sgRNA	''
cord-321013-8pkrg0mx	44	44	by	by	IN
cord-321013-8pkrg0mx	44	45	the	the	DT
cord-321013-8pkrg0mx	44	46	coronaviral	coronaviral	JJ
cord-321013-8pkrg0mx	44	47	replicase	replicase	NN
cord-321013-8pkrg0mx	44	48	complex	complex	NN
cord-321013-8pkrg0mx	44	49	[	[	-LRB-
cord-321013-8pkrg0mx	44	50	26	26	CD
cord-321013-8pkrg0mx	44	51	]	]	-RRB-
cord-321013-8pkrg0mx	44	52	.	.	.
cord-321013-8pkrg0mx	45	1	Three	three	CD
cord-321013-8pkrg0mx	45	2	residues	residue	NNS
cord-321013-8pkrg0mx	45	3	on	on	IN
cord-321013-8pkrg0mx	45	4	the	the	DT
cord-321013-8pkrg0mx	45	5	β	β	NN
cord-321013-8pkrg0mx	45	6	-	-	HYPH
cord-321013-8pkrg0mx	45	7	platform	platform	NN
cord-321013-8pkrg0mx	45	8	have	have	VBP
cord-321013-8pkrg0mx	45	9	been	be	VBN
cord-321013-8pkrg0mx	45	10	shown	show	VBN
cord-321013-8pkrg0mx	45	11	to	to	TO
cord-321013-8pkrg0mx	45	12	play	play	VB
cord-321013-8pkrg0mx	45	13	key	key	JJ
cord-321013-8pkrg0mx	45	14	roles	role	NNS
cord-321013-8pkrg0mx	45	15	in	in	IN
cord-321013-8pkrg0mx	45	16	TRS	TRS	NNP
cord-321013-8pkrg0mx	45	17	binding	binding	NN
cord-321013-8pkrg0mx	45	18	and	and	CC
cord-321013-8pkrg0mx	45	19	helix	helix	NN
cord-321013-8pkrg0mx	45	20	destabilization	destabilization	NN
cord-321013-8pkrg0mx	45	21	:	:	:
cord-321013-8pkrg0mx	45	22	Arg-125	arg-125	NN
cord-321013-8pkrg0mx	45	23	and	and	CC
cord-321013-8pkrg0mx	45	24	Tyr-127	Tyr-127	NNP
cord-321013-8pkrg0mx	45	25	on	on	IN
cord-321013-8pkrg0mx	45	26	the	the	DT
cord-321013-8pkrg0mx	45	27	β3	β3	NNP
cord-321013-8pkrg0mx	45	28	strand	strand	NN
cord-321013-8pkrg0mx	45	29	and	and	CC
cord-321013-8pkrg0mx	45	30	Tyr-190	tyr-190	NN
cord-321013-8pkrg0mx	45	31	on	on	IN
cord-321013-8pkrg0mx	45	32	the	the	DT
cord-321013-8pkrg0mx	45	33	β5	β5	NNP
cord-321013-8pkrg0mx	45	34	strand	strand	NN
cord-321013-8pkrg0mx	45	35	,	,	,
cord-321013-8pkrg0mx	45	36	suggesting	suggest	VBG
cord-321013-8pkrg0mx	45	37	that	that	IN
cord-321013-8pkrg0mx	45	38	the	the	DT
cord-321013-8pkrg0mx	45	39	AAA	AAA	NNP
cord-321013-8pkrg0mx	45	40	motif	motif	NN
cord-321013-8pkrg0mx	45	41	in	in	IN
cord-321013-8pkrg0mx	45	42	the	the	DT
cord-321013-8pkrg0mx	45	43	3'-end	3'-end	CD
cord-321013-8pkrg0mx	45	44	of	of	IN
cord-321013-8pkrg0mx	45	45	the	the	DT
cord-321013-8pkrg0mx	45	46	TRS	TRS	NNP
cord-321013-8pkrg0mx	45	47	is	be	VBZ
cord-321013-8pkrg0mx	45	48	anchored	anchor	VBN
cord-321013-8pkrg0mx	45	49	here	here	RB
cord-321013-8pkrg0mx	45	50	[	[	-LRB-
cord-321013-8pkrg0mx	45	51	18	18	CD
cord-321013-8pkrg0mx	45	52	]	]	-RRB-
cord-321013-8pkrg0mx	45	53	.	.	.
cord-321013-8pkrg0mx	46	1	These	these	DT
cord-321013-8pkrg0mx	46	2	three	three	CD
cord-321013-8pkrg0mx	46	3	residues	residue	NNS
cord-321013-8pkrg0mx	46	4	are	be	VBP
cord-321013-8pkrg0mx	46	5	completely	completely	RB
cord-321013-8pkrg0mx	46	6	invariant	invariant	JJ
cord-321013-8pkrg0mx	46	7	in	in	IN
cord-321013-8pkrg0mx	46	8	betacoronavirus	betacoronavirus	NNP
cord-321013-8pkrg0mx	46	9	N	n	CD
cord-321013-8pkrg0mx	46	10	proteins	protein	NNS
cord-321013-8pkrg0mx	46	11	and	and	CC
cord-321013-8pkrg0mx	46	12	occupy	occupy	VBP
cord-321013-8pkrg0mx	46	13	precisely	precisely	RB
cord-321013-8pkrg0mx	46	14	analogous	analogous	JJ
cord-321013-8pkrg0mx	46	15	positions	position	NNS
cord-321013-8pkrg0mx	46	16	on	on	IN
cord-321013-8pkrg0mx	46	17	the	the	DT
cord-321013-8pkrg0mx	46	18	fold	fold	NN
cord-321013-8pkrg0mx	46	19	of	of	IN
cord-321013-8pkrg0mx	46	20	each	each	DT
cord-321013-8pkrg0mx	46	21	NTD	NTD	NNP
cord-321013-8pkrg0mx	46	22	,	,	,
cord-321013-8pkrg0mx	46	23	and	and	CC
cord-321013-8pkrg0mx	46	24	are	be	VBP
cord-321013-8pkrg0mx	46	25	therefore	therefore	RB
cord-321013-8pkrg0mx	46	26	likely	likely	JJ
cord-321013-8pkrg0mx	46	27	to	to	TO
cord-321013-8pkrg0mx	46	28	define	define	VB
cord-321013-8pkrg0mx	46	29	similar	similar	JJ
cord-321013-8pkrg0mx	46	30	RNA	RNA	NNP
cord-321013-8pkrg0mx	46	31	binding	bind	VBG
cord-321013-8pkrg0mx	46	32	grooves	groove	NNS
cord-321013-8pkrg0mx	46	33	in	in	IN
cord-321013-8pkrg0mx	46	34	the	the	DT
cord-321013-8pkrg0mx	46	35	closely	closely	RB
cord-321013-8pkrg0mx	46	36	related	relate	VBN
cord-321013-8pkrg0mx	46	37	SARS	SARS	NNP
cord-321013-8pkrg0mx	46	38	NTD	NTD	NNP
cord-321013-8pkrg0mx	46	39	[	[	-LRB-
cord-321013-8pkrg0mx	46	40	18	18	CD
cord-321013-8pkrg0mx	46	41	]	]	-RRB-
cord-321013-8pkrg0mx	46	42	.	.	.
cord-321013-8pkrg0mx	47	1	The	the	DT
cord-321013-8pkrg0mx	47	2	duplex	duplex	NN
cord-321013-8pkrg0mx	47	3	formation	formation	NN
cord-321013-8pkrg0mx	47	4	and	and	CC
cord-321013-8pkrg0mx	47	5	duplex	duplex	NN
cord-321013-8pkrg0mx	47	6	TRS	TRS	NNP
cord-321013-8pkrg0mx	47	7	unwinding	unwinding	NN
cord-321013-8pkrg0mx	47	8	activity	activity	NN
cord-321013-8pkrg0mx	47	9	exhibited	exhibit	VBN
cord-321013-8pkrg0mx	47	10	by	by	IN
cord-321013-8pkrg0mx	47	11	N219	N219	NNPS
cord-321013-8pkrg0mx	47	12	therefore	therefore	RB
cord-321013-8pkrg0mx	47	13	implicates	implicate	VBZ
cord-321013-8pkrg0mx	47	14	MHV	MHV	NNP
cord-321013-8pkrg0mx	47	15	NTD	NTD	NNP
cord-321013-8pkrg0mx	47	16	in	in	IN
cord-321013-8pkrg0mx	47	17	template	template	NN
cord-321013-8pkrg0mx	47	18	switching	switch	VBG
cord-321013-8pkrg0mx	47	19	during	during	IN
cord-321013-8pkrg0mx	47	20	discontinuous	discontinuous	JJ
cord-321013-8pkrg0mx	47	21	sgRNA	sgRNA	NNS
cord-321013-8pkrg0mx	47	22	transcription	transcription	NN
cord-321013-8pkrg0mx	47	23	[	[	-LRB-
cord-321013-8pkrg0mx	47	24	28	28	CD
cord-321013-8pkrg0mx	47	25	,	,	,
cord-321013-8pkrg0mx	47	26	29	29	CD
cord-321013-8pkrg0mx	47	27	]	]	-RRB-
cord-321013-8pkrg0mx	47	28	.	.	.
cord-321013-8pkrg0mx	48	1	Moreover	moreover	RB
cord-321013-8pkrg0mx	48	2	,	,	,
cord-321013-8pkrg0mx	48	3	the	the	DT
cord-321013-8pkrg0mx	48	4	ability	ability	NN
cord-321013-8pkrg0mx	48	5	of	of	IN
cord-321013-8pkrg0mx	48	6	the	the	DT
cord-321013-8pkrg0mx	48	7	NTD	NTD	NNP
cord-321013-8pkrg0mx	48	8	to	to	TO
cord-321013-8pkrg0mx	48	9	melt	melt	VB
cord-321013-8pkrg0mx	48	10	dsRNA	dsrna	NN
cord-321013-8pkrg0mx	48	11	may	may	MD
cord-321013-8pkrg0mx	48	12	also	also	RB
cord-321013-8pkrg0mx	48	13	play	play	VB
cord-321013-8pkrg0mx	48	14	a	a	DT
cord-321013-8pkrg0mx	48	15	role	role	NN
cord-321013-8pkrg0mx	48	16	in	in	IN
cord-321013-8pkrg0mx	48	17	RNA	RNA	NNP
cord-321013-8pkrg0mx	48	18	packaging	packaging	NN
cord-321013-8pkrg0mx	48	19	or	or	CC
cord-321013-8pkrg0mx	48	20	other	other	JJ
cord-321013-8pkrg0mx	48	21	steps	step	NNS
cord-321013-8pkrg0mx	48	22	in	in	IN
cord-321013-8pkrg0mx	48	23	the	the	DT
cord-321013-8pkrg0mx	48	24	viral	viral	JJ
cord-321013-8pkrg0mx	48	25	life	life	NN
cord-321013-8pkrg0mx	48	26	cycle	cycle	NN
cord-321013-8pkrg0mx	48	27	where	where	WRB
cord-321013-8pkrg0mx	48	28	RNA	RNA	NNP
cord-321013-8pkrg0mx	48	29	remodeling	remodeling	NN
cord-321013-8pkrg0mx	48	30	is	be	VBZ
cord-321013-8pkrg0mx	48	31	needed	need	VBN
cord-321013-8pkrg0mx	48	32	[	[	-LRB-
cord-321013-8pkrg0mx	48	33	26	26	CD
cord-321013-8pkrg0mx	48	34	]	]	-RRB-
cord-321013-8pkrg0mx	48	35	.	.	.
cord-321013-8pkrg0mx	49	1	For	for	IN
cord-321013-8pkrg0mx	49	2	example	example	NN
cord-321013-8pkrg0mx	49	3	,	,	,
cord-321013-8pkrg0mx	49	4	mutations	mutation	NNS
cord-321013-8pkrg0mx	49	5	that	that	IN
cord-321013-8pkrg0mx	49	6	cripple	cripple	VBP
cord-321013-8pkrg0mx	49	7	duplex	duplex	NN
cord-321013-8pkrg0mx	49	8	unwinding	unwinding	NN
cord-321013-8pkrg0mx	49	9	are	be	VBP
cord-321013-8pkrg0mx	49	10	defective	defective	JJ
cord-321013-8pkrg0mx	49	11	in	in	IN
cord-321013-8pkrg0mx	49	12	stimulating	stimulate	VBG
cord-321013-8pkrg0mx	49	13	CoV	cov	NN
cord-321013-8pkrg0mx	49	14	replication	replication	NN
cord-321013-8pkrg0mx	49	15	in	in	IN
cord-321013-8pkrg0mx	49	16	BHK	BHK	NNP
cord-321013-8pkrg0mx	49	17	-	-	HYPH
cord-321013-8pkrg0mx	49	18	R	r	JJ
cord-321013-8pkrg0mx	49	19	cells	cell	NNS
cord-321013-8pkrg0mx	49	20	,	,	,
cord-321013-8pkrg0mx	49	21	and	and	CC
cord-321013-8pkrg0mx	49	22	are	be	VBP
cord-321013-8pkrg0mx	49	23	lethal	lethal	JJ
cord-321013-8pkrg0mx	49	24	,	,	,
cord-321013-8pkrg0mx	49	25	providing	provide	VBG
cord-321013-8pkrg0mx	49	26	evidence	evidence	NN
cord-321013-8pkrg0mx	49	27	of	of	IN
cord-321013-8pkrg0mx	49	28	a	a	DT
cord-321013-8pkrg0mx	49	29	critical	critical	JJ
cord-321013-8pkrg0mx	49	30	role	role	NN
cord-321013-8pkrg0mx	49	31	for	for	IN
cord-321013-8pkrg0mx	49	32	NTD	NTD	NNP
cord-321013-8pkrg0mx	49	33	in	in	IN
cord-321013-8pkrg0mx	49	34	viral	viral	JJ
cord-321013-8pkrg0mx	49	35	replication	replication	NN
cord-321013-8pkrg0mx	49	36	[	[	-LRB-
cord-321013-8pkrg0mx	49	37	18	18	CD
cord-321013-8pkrg0mx	49	38	,	,	,
cord-321013-8pkrg0mx	49	39	26	26	CD
cord-321013-8pkrg0mx	49	40	]	]	-RRB-
cord-321013-8pkrg0mx	49	41	.	.	.
cord-321013-8pkrg0mx	50	1	CoV	CoV	NNP
cord-321013-8pkrg0mx	50	2	N	n	CD
cord-321013-8pkrg0mx	50	3	proteins	protein	NNS
cord-321013-8pkrg0mx	50	4	have	have	VBP
cord-321013-8pkrg0mx	50	5	also	also	RB
cord-321013-8pkrg0mx	50	6	been	be	VBN
cord-321013-8pkrg0mx	50	7	recognized	recognize	VBN
cord-321013-8pkrg0mx	50	8	as	as	IN
cord-321013-8pkrg0mx	50	9	RNA	RNA	NNP
cord-321013-8pkrg0mx	50	10	chaperones	chaperone	NNS
cord-321013-8pkrg0mx	50	11	[	[	-LRB-
cord-321013-8pkrg0mx	50	12	30	30	CD
cord-321013-8pkrg0mx	50	13	,	,	,
cord-321013-8pkrg0mx	50	14	31	31	CD
cord-321013-8pkrg0mx	50	15	]	]	-RRB-
cord-321013-8pkrg0mx	50	16	,	,	,
cord-321013-8pkrg0mx	50	17	which	which	WDT
cord-321013-8pkrg0mx	50	18	,	,	,
cord-321013-8pkrg0mx	50	19	as	as	IN
cord-321013-8pkrg0mx	50	20	part	part	NN
cord-321013-8pkrg0mx	50	21	of	of	IN
cord-321013-8pkrg0mx	50	22	their	-PRON-	PRP$
cord-321013-8pkrg0mx	50	23	chaperone	chaperone	NN
cord-321013-8pkrg0mx	50	24	activities	activity	NNS
cord-321013-8pkrg0mx	50	25	,	,	,
cord-321013-8pkrg0mx	50	26	anneal	anneal	VB
cord-321013-8pkrg0mx	50	27	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	50	28	acids	acid	NNS
cord-321013-8pkrg0mx	50	29	,	,	,
cord-321013-8pkrg0mx	50	30	and	and	CC
cord-321013-8pkrg0mx	50	31	so	so	RB
cord-321013-8pkrg0mx	50	32	RNA	RNA	NNP
cord-321013-8pkrg0mx	50	33	duplex	duplex	NN
cord-321013-8pkrg0mx	50	34	destabilization	destabilization	NN
cord-321013-8pkrg0mx	50	35	activity	activity	NN
cord-321013-8pkrg0mx	50	36	may	may	MD
cord-321013-8pkrg0mx	50	37	be	be	VB
cord-321013-8pkrg0mx	50	38	important	important	JJ
cord-321013-8pkrg0mx	50	39	in	in	IN
cord-321013-8pkrg0mx	50	40	CoV	CoV	NNP
cord-321013-8pkrg0mx	50	41	N	n	CD
cord-321013-8pkrg0mx	50	42	NTDs	NTDs	NNPS
cord-321013-8pkrg0mx	50	43	role	role	NN
cord-321013-8pkrg0mx	50	44	in	in	IN
cord-321013-8pkrg0mx	50	45	assisting	assist	VBG
cord-321013-8pkrg0mx	50	46	viral	viral	JJ
cord-321013-8pkrg0mx	50	47	RNA	RNA	NNP
cord-321013-8pkrg0mx	50	48	in	in	IN
cord-321013-8pkrg0mx	50	49	reaching	reach	VBG
cord-321013-8pkrg0mx	50	50	its	-PRON-	PRP$
cord-321013-8pkrg0mx	50	51	functional	functional	JJ
cord-321013-8pkrg0mx	50	52	three	three	CD
cord-321013-8pkrg0mx	50	53	-	-	HYPH
cord-321013-8pkrg0mx	50	54	dimentional	dimentional	JJ
cord-321013-8pkrg0mx	50	55	structure	structure	NN
cord-321013-8pkrg0mx	50	56	.	.	.
cord-321013-8pkrg0mx	51	1	Viral	viral	JJ
cord-321013-8pkrg0mx	51	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	51	3	and	and	CC
cord-321013-8pkrg0mx	51	4	replication	replication	NN
cord-321013-8pkrg0mx	51	5	accessory	accessory	NN
cord-321013-8pkrg0mx	51	6	proteins	protein	NNS
cord-321013-8pkrg0mx	51	7	from	from	IN
cord-321013-8pkrg0mx	51	8	other	other	JJ
cord-321013-8pkrg0mx	51	9	viruses	virus	NNS
cord-321013-8pkrg0mx	51	10	have	have	VBP
cord-321013-8pkrg0mx	51	11	also	also	RB
cord-321013-8pkrg0mx	51	12	been	be	VBN
cord-321013-8pkrg0mx	51	13	shown	show	VBN
cord-321013-8pkrg0mx	51	14	to	to	TO
cord-321013-8pkrg0mx	51	15	function	function	VB
cord-321013-8pkrg0mx	51	16	as	as	IN
cord-321013-8pkrg0mx	51	17	RNA	RNA	NNP
cord-321013-8pkrg0mx	51	18	chaperones	chaperone	NNS
cord-321013-8pkrg0mx	51	19	and	and	CC
cord-321013-8pkrg0mx	51	20	facilitate	facilitate	VB
cord-321013-8pkrg0mx	51	21	helix	helix	NN
cord-321013-8pkrg0mx	51	22	destabilization	destabilization	NN
cord-321013-8pkrg0mx	51	23	,	,	,
cord-321013-8pkrg0mx	51	24	for	for	IN
cord-321013-8pkrg0mx	51	25	example	example	NN
cord-321013-8pkrg0mx	51	26	HIV-1	HIV-1	NNP
cord-321013-8pkrg0mx	51	27	NCp7	ncp7	NN
cord-321013-8pkrg0mx	51	28	protein	protein	NN
cord-321013-8pkrg0mx	51	29	[	[	-LRB-
cord-321013-8pkrg0mx	51	30	32	32	CD
cord-321013-8pkrg0mx	51	31	]	]	-RRB-
cord-321013-8pkrg0mx	51	32	,	,	,
cord-321013-8pkrg0mx	51	33	and	and	CC
cord-321013-8pkrg0mx	51	34	adenovirus	adenovirus	NN
cord-321013-8pkrg0mx	51	35	DNA	dna	NN
cord-321013-8pkrg0mx	51	36	binding	bind	VBG
cord-321013-8pkrg0mx	51	37	protein	protein	NN
cord-321013-8pkrg0mx	51	38	[	[	-LRB-
cord-321013-8pkrg0mx	51	39	33	33	CD
cord-321013-8pkrg0mx	51	40	]	]	-RRB-
cord-321013-8pkrg0mx	51	41	.	.	.
cord-321013-8pkrg0mx	52	1	The	the	DT
cord-321013-8pkrg0mx	52	2	NTD	NTD	NNP
cord-321013-8pkrg0mx	52	3	is	be	VBZ
cord-321013-8pkrg0mx	52	4	separated	separate	VBN
cord-321013-8pkrg0mx	52	5	from	from	IN
cord-321013-8pkrg0mx	52	6	the	the	DT
cord-321013-8pkrg0mx	52	7	CTD	CTD	NNP
cord-321013-8pkrg0mx	52	8	by	by	IN
cord-321013-8pkrg0mx	52	9	an	an	DT
cord-321013-8pkrg0mx	52	10	intrinsically	intrinsically	RB
cord-321013-8pkrg0mx	52	11	disordered	disordered	JJ
cord-321013-8pkrg0mx	52	12	middle	middle	JJ
cord-321013-8pkrg0mx	52	13	region	region	NN
cord-321013-8pkrg0mx	52	14	referred	refer	VBD
cord-321013-8pkrg0mx	52	15	to	to	IN
cord-321013-8pkrg0mx	52	16	as	as	IN
cord-321013-8pkrg0mx	52	17	the	the	DT
cord-321013-8pkrg0mx	52	18	linker	linker	NN
cord-321013-8pkrg0mx	52	19	region	region	NN
cord-321013-8pkrg0mx	52	20	(	(	-LRB-
cord-321013-8pkrg0mx	52	21	LKR	LKR	NNP
cord-321013-8pkrg0mx	52	22	)	)	-RRB-
cord-321013-8pkrg0mx	52	23	.	.	.
cord-321013-8pkrg0mx	53	1	The	the	DT
cord-321013-8pkrg0mx	53	2	charged	charge	VBN
cord-321013-8pkrg0mx	53	3	LKR	LKR	NNP
cord-321013-8pkrg0mx	53	4	is	be	VBZ
cord-321013-8pkrg0mx	53	5	also	also	RB
cord-321013-8pkrg0mx	53	6	known	know	VBN
cord-321013-8pkrg0mx	53	7	as	as	IN
cord-321013-8pkrg0mx	53	8	the	the	DT
cord-321013-8pkrg0mx	53	9	SR	SR	NNP
cord-321013-8pkrg0mx	53	10	-	-	HYPH
cord-321013-8pkrg0mx	53	11	domain	domain	NN
cord-321013-8pkrg0mx	53	12	because	because	IN
cord-321013-8pkrg0mx	53	13	it	-PRON-	PRP
cord-321013-8pkrg0mx	53	14	is	be	VBZ
cord-321013-8pkrg0mx	53	15	rich	rich	JJ
cord-321013-8pkrg0mx	53	16	in	in	IN
cord-321013-8pkrg0mx	53	17	serine	serine	NN
cord-321013-8pkrg0mx	53	18	and	and	CC
cord-321013-8pkrg0mx	53	19	arginine	arginine	NN
cord-321013-8pkrg0mx	53	20	residues	residue	NNS
cord-321013-8pkrg0mx	53	21	[	[	-LRB-
cord-321013-8pkrg0mx	53	22	34	34	CD
cord-321013-8pkrg0mx	53	23	]	]	-RRB-
cord-321013-8pkrg0mx	53	24	,	,	,
cord-321013-8pkrg0mx	53	25	and	and	CC
cord-321013-8pkrg0mx	53	26	it	-PRON-	PRP
cord-321013-8pkrg0mx	53	27	is	be	VBZ
cord-321013-8pkrg0mx	53	28	involved	involve	VBN
cord-321013-8pkrg0mx	53	29	in	in	IN
cord-321013-8pkrg0mx	53	30	cell	cell	NN
cord-321013-8pkrg0mx	53	31	signaling	signal	VBG
cord-321013-8pkrg0mx	53	32	[	[	-LRB-
cord-321013-8pkrg0mx	53	33	15	15	CD
cord-321013-8pkrg0mx	53	34	,	,	,
cord-321013-8pkrg0mx	53	35	35	35	CD
cord-321013-8pkrg0mx	53	36	,	,	,
cord-321013-8pkrg0mx	53	37	36	36	CD
cord-321013-8pkrg0mx	53	38	]	]	-RRB-
cord-321013-8pkrg0mx	53	39	.	.	.
cord-321013-8pkrg0mx	54	1	The	the	DT
cord-321013-8pkrg0mx	54	2	flexible	flexible	JJ
cord-321013-8pkrg0mx	54	3	LKR	LKR	NNP
cord-321013-8pkrg0mx	54	4	is	be	VBZ
cord-321013-8pkrg0mx	54	5	capable	capable	JJ
cord-321013-8pkrg0mx	54	6	of	of	IN
cord-321013-8pkrg0mx	54	7	direct	direct	JJ
cord-321013-8pkrg0mx	54	8	interaction	interaction	NN
cord-321013-8pkrg0mx	54	9	with	with	IN
cord-321013-8pkrg0mx	54	10	RNA	RNA	NNP
cord-321013-8pkrg0mx	54	11	under	under	IN
cord-321013-8pkrg0mx	54	12	in	in	IN
cord-321013-8pkrg0mx	54	13	vitro	vitro	FW
cord-321013-8pkrg0mx	54	14	conditions	condition	NNS
cord-321013-8pkrg0mx	54	15	[	[	-LRB-
cord-321013-8pkrg0mx	54	16	37	37	CD
cord-321013-8pkrg0mx	54	17	]	]	-RRB-
cord-321013-8pkrg0mx	54	18	.	.	.
cord-321013-8pkrg0mx	55	1	Potential	potential	JJ
cord-321013-8pkrg0mx	55	2	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	55	3	sites	site	NNS
cord-321013-8pkrg0mx	55	4	have	have	VBP
cord-321013-8pkrg0mx	55	5	been	be	VBN
cord-321013-8pkrg0mx	55	6	mapped	map	VBN
cord-321013-8pkrg0mx	55	7	to	to	IN
cord-321013-8pkrg0mx	55	8	the	the	DT
cord-321013-8pkrg0mx	55	9	Ser	Ser	NNP
cord-321013-8pkrg0mx	55	10	/	/	SYM
cord-321013-8pkrg0mx	55	11	Arg	arg	JJ
cord-321013-8pkrg0mx	55	12	-	-	HYPH
cord-321013-8pkrg0mx	55	13	rich	rich	JJ
cord-321013-8pkrg0mx	55	14	portion	portion	NN
cord-321013-8pkrg0mx	55	15	of	of	IN
cord-321013-8pkrg0mx	55	16	the	the	DT
cord-321013-8pkrg0mx	55	17	LKR	LKR	NNP
cord-321013-8pkrg0mx	55	18	of	of	IN
cord-321013-8pkrg0mx	55	19	SARS	SARS	NNP
cord-321013-8pkrg0mx	55	20	-	-	HYPH
cord-321013-8pkrg0mx	55	21	CoV	CoV	NNP
cord-321013-8pkrg0mx	55	22	N	N	NNP
cord-321013-8pkrg0mx	55	23	[	[	-LRB-
cord-321013-8pkrg0mx	55	24	38	38	CD
cord-321013-8pkrg0mx	55	25	]	]	-RRB-
cord-321013-8pkrg0mx	55	26	[	[	-LRB-
cord-321013-8pkrg0mx	55	27	39	39	CD
cord-321013-8pkrg0mx	55	28	]	]	-RRB-
cord-321013-8pkrg0mx	55	29	[	[	-LRB-
cord-321013-8pkrg0mx	55	30	40	40	CD
cord-321013-8pkrg0mx	55	31	]	]	-RRB-
cord-321013-8pkrg0mx	55	32	.	.	.
cord-321013-8pkrg0mx	56	1	These	these	DT
cord-321013-8pkrg0mx	56	2	LKR	LKR	NNP
cord-321013-8pkrg0mx	56	3	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	56	4	sites	site	NNS
cord-321013-8pkrg0mx	56	5	are	be	VBP
cord-321013-8pkrg0mx	56	6	thought	think	VBN
cord-321013-8pkrg0mx	56	7	to	to	TO
cord-321013-8pkrg0mx	56	8	function	function	VB
cord-321013-8pkrg0mx	56	9	in	in	IN
cord-321013-8pkrg0mx	56	10	binding	bind	VBG
cord-321013-8pkrg0mx	56	11	M	M	NNP
cord-321013-8pkrg0mx	56	12	protein	protein	NN
cord-321013-8pkrg0mx	56	13	,	,	,
cord-321013-8pkrg0mx	56	14	heteronuclear	heteronuclear	NNP
cord-321013-8pkrg0mx	56	15	ribonucleoprotein	ribonucleoprotein	NN
cord-321013-8pkrg0mx	56	16	(	(	-LRB-
cord-321013-8pkrg0mx	56	17	hnRNP	hnRNP	NNP
cord-321013-8pkrg0mx	56	18	-	-	HYPH
cord-321013-8pkrg0mx	56	19	A1	a1	NN
cord-321013-8pkrg0mx	56	20	)	)	-RRB-
cord-321013-8pkrg0mx	56	21	and	and	CC
cord-321013-8pkrg0mx	56	22	RNA	RNA	NNP
cord-321013-8pkrg0mx	56	23	to	to	IN
cord-321013-8pkrg0mx	56	24	the	the	DT
cord-321013-8pkrg0mx	56	25	N	n	CD
cord-321013-8pkrg0mx	56	26	protein	protein	NN
cord-321013-8pkrg0mx	56	27	with	with	IN
cord-321013-8pkrg0mx	56	28	high	high	JJ
cord-321013-8pkrg0mx	56	29	binding	binding	NN
cord-321013-8pkrg0mx	56	30	affinity	affinity	NN
cord-321013-8pkrg0mx	56	31	[	[	-LRB-
cord-321013-8pkrg0mx	56	32	14	14	CD
cord-321013-8pkrg0mx	56	33	,	,	,
cord-321013-8pkrg0mx	56	34	[	[	-LRB-
cord-321013-8pkrg0mx	56	35	41	41	CD
cord-321013-8pkrg0mx	56	36	]	]	-RRB-
cord-321013-8pkrg0mx	57	1	[	[	-LRB-
cord-321013-8pkrg0mx	57	2	42	42	CD
cord-321013-8pkrg0mx	57	3	]	]	-RRB-
cord-321013-8pkrg0mx	57	4	[	[	-LRB-
cord-321013-8pkrg0mx	57	5	43	43	CD
cord-321013-8pkrg0mx	57	6	]	]	-RRB-
cord-321013-8pkrg0mx	57	7	.	.	.
cord-321013-8pkrg0mx	58	1	There	there	EX
cord-321013-8pkrg0mx	58	2	are	be	VBP
cord-321013-8pkrg0mx	58	3	conflicting	conflict	VBG
cord-321013-8pkrg0mx	58	4	reports	report	NNS
cord-321013-8pkrg0mx	58	5	regarding	regard	VBG
cord-321013-8pkrg0mx	58	6	the	the	DT
cord-321013-8pkrg0mx	58	7	involvement	involvement	NN
cord-321013-8pkrg0mx	58	8	of	of	IN
cord-321013-8pkrg0mx	58	9	the	the	DT
cord-321013-8pkrg0mx	58	10	LKR	LKR	NNP
cord-321013-8pkrg0mx	58	11	in	in	IN
cord-321013-8pkrg0mx	58	12	N	N	NNP
cord-321013-8pkrg0mx	58	13	protein	protein	NN
cord-321013-8pkrg0mx	58	14	oligomerization	oligomerization	NN
cord-321013-8pkrg0mx	58	15	.	.	.
cord-321013-8pkrg0mx	59	1	Some	some	DT
cord-321013-8pkrg0mx	59	2	studies	study	NNS
cord-321013-8pkrg0mx	59	3	has	have	VBZ
cord-321013-8pkrg0mx	59	4	suggested	suggest	VBN
cord-321013-8pkrg0mx	59	5	that	that	IN
cord-321013-8pkrg0mx	59	6	the	the	DT
cord-321013-8pkrg0mx	59	7	LKR	LKR	NNP
cord-321013-8pkrg0mx	59	8	is	be	VBZ
cord-321013-8pkrg0mx	59	9	directly	directly	RB
cord-321013-8pkrg0mx	59	10	involved	involve	VBN
cord-321013-8pkrg0mx	59	11	[	[	-LRB-
cord-321013-8pkrg0mx	59	12	44	44	CD
cord-321013-8pkrg0mx	59	13	]	]	-RRB-
cord-321013-8pkrg0mx	59	14	and	and	CC
cord-321013-8pkrg0mx	59	15	that	that	IN
cord-321013-8pkrg0mx	59	16	through	through	IN
cord-321013-8pkrg0mx	59	17	electrostatic	electrostatic	JJ
cord-321013-8pkrg0mx	59	18	effects	effect	NNS
cord-321013-8pkrg0mx	59	19	,	,	,
cord-321013-8pkrg0mx	59	20	hyperphosphorylation	hyperphosphorylation	NN
cord-321013-8pkrg0mx	59	21	of	of	IN
cord-321013-8pkrg0mx	59	22	the	the	DT
cord-321013-8pkrg0mx	59	23	LKR	LKR	NNP
cord-321013-8pkrg0mx	59	24	reduces	reduce	VBZ
cord-321013-8pkrg0mx	59	25	the	the	DT
cord-321013-8pkrg0mx	59	26	total	total	JJ
cord-321013-8pkrg0mx	59	27	positive	positive	JJ
cord-321013-8pkrg0mx	59	28	charge	charge	NN
cord-321013-8pkrg0mx	59	29	on	on	IN
cord-321013-8pkrg0mx	59	30	the	the	DT
cord-321013-8pkrg0mx	59	31	SARS	SARS	NNP
cord-321013-8pkrg0mx	59	32	-	-	HYPH
cord-321013-8pkrg0mx	59	33	CoV	CoV	NNP
cord-321013-8pkrg0mx	59	34	N	n	CD
cord-321013-8pkrg0mx	59	35	protein	protein	NN
cord-321013-8pkrg0mx	59	36	and	and	CC
cord-321013-8pkrg0mx	59	37	leads	lead	VBZ
cord-321013-8pkrg0mx	59	38	to	to	IN
cord-321013-8pkrg0mx	59	39	enhanced	enhance	VBN
cord-321013-8pkrg0mx	59	40	oligomerization	oligomerization	NN
cord-321013-8pkrg0mx	59	41	of	of	IN
cord-321013-8pkrg0mx	59	42	di	di	NN
cord-321013-8pkrg0mx	59	43	-	-	NN
cord-321013-8pkrg0mx	59	44	domain	domain	NN
cord-321013-8pkrg0mx	59	45	constructs	construct	NNS
cord-321013-8pkrg0mx	59	46	[	[	-LRB-
cord-321013-8pkrg0mx	59	47	45	45	CD
cord-321013-8pkrg0mx	59	48	]	]	-RRB-
cord-321013-8pkrg0mx	59	49	.	.	.
cord-321013-8pkrg0mx	60	1	Other	other	JJ
cord-321013-8pkrg0mx	60	2	studies	study	NNS
cord-321013-8pkrg0mx	60	3	have	have	VBP
cord-321013-8pkrg0mx	60	4	,	,	,
cord-321013-8pkrg0mx	60	5	however	however	RB
cord-321013-8pkrg0mx	60	6	,	,	,
cord-321013-8pkrg0mx	60	7	reported	report	VBD
cord-321013-8pkrg0mx	60	8	that	that	IN
cord-321013-8pkrg0mx	60	9	the	the	DT
cord-321013-8pkrg0mx	60	10	LKR	LKR	NNP
cord-321013-8pkrg0mx	60	11	interferes	interfere	VBZ
cord-321013-8pkrg0mx	60	12	with	with	IN
cord-321013-8pkrg0mx	60	13	oligomerization	oligomerization	NN
cord-321013-8pkrg0mx	60	14	when	when	WRB
cord-321013-8pkrg0mx	60	15	the	the	DT
cord-321013-8pkrg0mx	60	16	CTD	CTD	NNP
cord-321013-8pkrg0mx	60	17	is	be	VBZ
cord-321013-8pkrg0mx	60	18	present	present	JJ
cord-321013-8pkrg0mx	60	19	[	[	-LRB-
cord-321013-8pkrg0mx	60	20	46	46	CD
cord-321013-8pkrg0mx	60	21	]	]	-RRB-
cord-321013-8pkrg0mx	60	22	or	or	CC
cord-321013-8pkrg0mx	60	23	if	if	IN
cord-321013-8pkrg0mx	60	24	the	the	DT
cord-321013-8pkrg0mx	60	25	LKR	LKR	NNP
cord-321013-8pkrg0mx	60	26	is	be	VBZ
cord-321013-8pkrg0mx	60	27	phosphorylated	phosphorylate	VBN
cord-321013-8pkrg0mx	60	28	[	[	-LRB-
cord-321013-8pkrg0mx	60	29	38	38	CD
cord-321013-8pkrg0mx	60	30	]	]	-RRB-
cord-321013-8pkrg0mx	60	31	.	.	.
cord-321013-8pkrg0mx	61	1	Despite	despite	IN
cord-321013-8pkrg0mx	61	2	almost	almost	RB
cord-321013-8pkrg0mx	61	3	no	no	DT
cord-321013-8pkrg0mx	61	4	structural	structural	JJ
cord-321013-8pkrg0mx	61	5	information	information	NN
cord-321013-8pkrg0mx	61	6	being	be	VBG
cord-321013-8pkrg0mx	61	7	available	available	JJ
cord-321013-8pkrg0mx	61	8	for	for	IN
cord-321013-8pkrg0mx	61	9	the	the	DT
cord-321013-8pkrg0mx	61	10	LKR	LKR	NNP
cord-321013-8pkrg0mx	61	11	,	,	,
cord-321013-8pkrg0mx	61	12	possibly	possibly	RB
cord-321013-8pkrg0mx	61	13	due	due	IN
cord-321013-8pkrg0mx	61	14	to	to	IN
cord-321013-8pkrg0mx	61	15	its	-PRON-	PRP$
cord-321013-8pkrg0mx	61	16	high	high	JJ
cord-321013-8pkrg0mx	61	17	positive	positive	JJ
cord-321013-8pkrg0mx	61	18	charge	charge	NN
cord-321013-8pkrg0mx	61	19	and	and	CC
cord-321013-8pkrg0mx	61	20	flexible	flexible	JJ
cord-321013-8pkrg0mx	61	21	nature	nature	NN
cord-321013-8pkrg0mx	61	22	[	[	-LRB-
cord-321013-8pkrg0mx	61	23	47	47	CD
cord-321013-8pkrg0mx	61	24	]	]	-RRB-
cord-321013-8pkrg0mx	61	25	,	,	,
cord-321013-8pkrg0mx	61	26	there	there	EX
cord-321013-8pkrg0mx	61	27	is	be	VBZ
cord-321013-8pkrg0mx	61	28	evidence	evidence	NN
cord-321013-8pkrg0mx	61	29	in	in	IN
cord-321013-8pkrg0mx	61	30	support	support	NN
cord-321013-8pkrg0mx	61	31	of	of	IN
cord-321013-8pkrg0mx	61	32	the	the	DT
cord-321013-8pkrg0mx	61	33	functional	functional	JJ
cord-321013-8pkrg0mx	61	34	importance	importance	NN
cord-321013-8pkrg0mx	61	35	of	of	IN
cord-321013-8pkrg0mx	61	36	intrinsically	intrinsically	RB
cord-321013-8pkrg0mx	61	37	disordered	disordered	JJ
cord-321013-8pkrg0mx	61	38	regions	region	NNS
cord-321013-8pkrg0mx	61	39	in	in	IN
cord-321013-8pkrg0mx	61	40	proteins	protein	NNS
cord-321013-8pkrg0mx	61	41	for	for	IN
cord-321013-8pkrg0mx	61	42	modulating	modulate	VBG
cord-321013-8pkrg0mx	61	43	transcription	transcription	NN
cord-321013-8pkrg0mx	61	44	,	,	,
cord-321013-8pkrg0mx	61	45	translation	translation	NN
cord-321013-8pkrg0mx	61	46	,	,	,
cord-321013-8pkrg0mx	61	47	post	post	JJ
cord-321013-8pkrg0mx	61	48	-	-	JJ
cord-321013-8pkrg0mx	61	49	translational	translational	JJ
cord-321013-8pkrg0mx	61	50	modifications	modification	NNS
cord-321013-8pkrg0mx	61	51	such	such	JJ
cord-321013-8pkrg0mx	61	52	as	as	IN
cord-321013-8pkrg0mx	61	53	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	61	54	,	,	,
cord-321013-8pkrg0mx	61	55	and	and	CC
cord-321013-8pkrg0mx	61	56	cell	cell	NN
cord-321013-8pkrg0mx	61	57	signaling	signal	VBG
cord-321013-8pkrg0mx	61	58	[	[	-LRB-
cord-321013-8pkrg0mx	61	59	48	48	CD
cord-321013-8pkrg0mx	61	60	]	]	-RRB-
cord-321013-8pkrg0mx	61	61	.	.	.
cord-321013-8pkrg0mx	62	1	RNA	RNA	NNP
cord-321013-8pkrg0mx	62	2	chaperones	chaperone	NNS
cord-321013-8pkrg0mx	62	3	often	often	RB
cord-321013-8pkrg0mx	62	4	have	have	VBP
cord-321013-8pkrg0mx	62	5	structural	structural	JJ
cord-321013-8pkrg0mx	62	6	flexibility	flexibility	NN
cord-321013-8pkrg0mx	62	7	because	because	IN
cord-321013-8pkrg0mx	62	8	the	the	DT
cord-321013-8pkrg0mx	62	9	RNA	RNA	NNP
cord-321013-8pkrg0mx	62	10	-	-	HYPH
cord-321013-8pkrg0mx	62	11	protein	protein	NN
cord-321013-8pkrg0mx	62	12	recognition	recognition	NN
cord-321013-8pkrg0mx	62	13	process	process	NN
cord-321013-8pkrg0mx	62	14	often	often	RB
cord-321013-8pkrg0mx	62	15	requires	require	VBZ
cord-321013-8pkrg0mx	62	16	conformational	conformational	JJ
cord-321013-8pkrg0mx	62	17	changes	change	NNS
cord-321013-8pkrg0mx	62	18	in	in	IN
cord-321013-8pkrg0mx	62	19	the	the	DT
cord-321013-8pkrg0mx	62	20	RNA	RNA	NNP
cord-321013-8pkrg0mx	62	21	,	,	,
cord-321013-8pkrg0mx	62	22	the	the	DT
cord-321013-8pkrg0mx	62	23	protein	protein	NN
cord-321013-8pkrg0mx	62	24	or	or	CC
cord-321013-8pkrg0mx	62	25	both	both	DT
cord-321013-8pkrg0mx	62	26	[	[	-LRB-
cord-321013-8pkrg0mx	62	27	49	49	CD
cord-321013-8pkrg0mx	62	28	]	]	-RRB-
cord-321013-8pkrg0mx	62	29	.	.	.
cord-321013-8pkrg0mx	63	1	An	an	DT
cord-321013-8pkrg0mx	63	2	interaction	interaction	NN
cord-321013-8pkrg0mx	63	3	between	between	IN
cord-321013-8pkrg0mx	63	4	N	n	CD
cord-321013-8pkrg0mx	63	5	protein	protein	NN
cord-321013-8pkrg0mx	63	6	and	and	CC
cord-321013-8pkrg0mx	63	7	a	a	DT
cord-321013-8pkrg0mx	63	8	subunit	subunit	NN
cord-321013-8pkrg0mx	63	9	of	of	IN
cord-321013-8pkrg0mx	63	10	the	the	DT
cord-321013-8pkrg0mx	63	11	viral	viral	JJ
cord-321013-8pkrg0mx	63	12	replicase	replicase	NN
cord-321013-8pkrg0mx	63	13	-	-	HYPH
cord-321013-8pkrg0mx	63	14	transcriptase	transcriptase	NN
cord-321013-8pkrg0mx	63	15	complex	complex	NN
cord-321013-8pkrg0mx	63	16	,	,	,
cord-321013-8pkrg0mx	63	17	namely	namely	RB
cord-321013-8pkrg0mx	63	18	non	non	JJ
cord-321013-8pkrg0mx	63	19	-	-	JJ
cord-321013-8pkrg0mx	63	20	structural	structural	JJ
cord-321013-8pkrg0mx	63	21	protein	protein	NN
cord-321013-8pkrg0mx	63	22	3	3	CD
cord-321013-8pkrg0mx	63	23	(	(	-LRB-
cord-321013-8pkrg0mx	63	24	nsp3	nsp3	NNS
cord-321013-8pkrg0mx	63	25	)	)	-RRB-
cord-321013-8pkrg0mx	63	26	,	,	,
cord-321013-8pkrg0mx	63	27	has	have	VBZ
cord-321013-8pkrg0mx	63	28	been	be	VBN
cord-321013-8pkrg0mx	63	29	described	describe	VBN
cord-321013-8pkrg0mx	63	30	and	and	CC
cord-321013-8pkrg0mx	63	31	key	key	JJ
cord-321013-8pkrg0mx	63	32	binding	bind	VBG
cord-321013-8pkrg0mx	63	33	determinants	determinant	NNS
cord-321013-8pkrg0mx	63	34	localize	localize	VBP
cord-321013-8pkrg0mx	63	35	to	to	IN
cord-321013-8pkrg0mx	63	36	the	the	DT
cord-321013-8pkrg0mx	63	37	LKR	LKR	NNP
cord-321013-8pkrg0mx	63	38	[	[	-LRB-
cord-321013-8pkrg0mx	63	39	50,51	50,51	CD
cord-321013-8pkrg0mx	63	40	]	]	-RRB-
cord-321013-8pkrg0mx	63	41	,	,	,
cord-321013-8pkrg0mx	63	42	highlighting	highlight	VBG
cord-321013-8pkrg0mx	63	43	the	the	DT
cord-321013-8pkrg0mx	63	44	importance	importance	NN
cord-321013-8pkrg0mx	63	45	of	of	IN
cord-321013-8pkrg0mx	63	46	this	this	DT
cord-321013-8pkrg0mx	63	47	unstructured	unstructured	JJ
cord-321013-8pkrg0mx	63	48	region	region	NN
cord-321013-8pkrg0mx	63	49	for	for	IN
cord-321013-8pkrg0mx	63	50	a	a	DT
cord-321013-8pkrg0mx	63	51	number	number	NN
cord-321013-8pkrg0mx	63	52	of	of	IN
cord-321013-8pkrg0mx	63	53	potential	potential	JJ
cord-321013-8pkrg0mx	63	54	interactions	interaction	NNS
cord-321013-8pkrg0mx	63	55	,	,	,
cord-321013-8pkrg0mx	63	56	such	such	JJ
cord-321013-8pkrg0mx	63	57	as	as	IN
cord-321013-8pkrg0mx	63	58	viral	viral	JJ
cord-321013-8pkrg0mx	63	59	infectivity	infectivity	NN
cord-321013-8pkrg0mx	63	60	[	[	-LRB-
cord-321013-8pkrg0mx	63	61	52	52	CD
cord-321013-8pkrg0mx	63	62	]	]	-RRB-
cord-321013-8pkrg0mx	63	63	.	.	.
cord-321013-8pkrg0mx	64	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	64	2	has	have	VBZ
cord-321013-8pkrg0mx	64	3	also	also	RB
cord-321013-8pkrg0mx	64	4	been	be	VBN
cord-321013-8pkrg0mx	64	5	proposed	propose	VBN
cord-321013-8pkrg0mx	64	6	that	that	IN
cord-321013-8pkrg0mx	64	7	nsp3	nsp3	NNS
cord-321013-8pkrg0mx	64	8	binding	bind	VBG
cord-321013-8pkrg0mx	64	9	induces	induce	VBZ
cord-321013-8pkrg0mx	64	10	a	a	DT
cord-321013-8pkrg0mx	64	11	conformational	conformational	JJ
cord-321013-8pkrg0mx	64	12	change	change	NN
cord-321013-8pkrg0mx	64	13	in	in	IN
cord-321013-8pkrg0mx	64	14	the	the	DT
cord-321013-8pkrg0mx	64	15	LKR	LKR	NNP
cord-321013-8pkrg0mx	64	16	,	,	,
cord-321013-8pkrg0mx	64	17	potentially	potentially	RB
cord-321013-8pkrg0mx	64	18	regulating	regulate	VBG
cord-321013-8pkrg0mx	64	19	the	the	DT
cord-321013-8pkrg0mx	64	20	intracellular	intracellular	JJ
cord-321013-8pkrg0mx	64	21	localization	localization	NN
cord-321013-8pkrg0mx	64	22	of	of	IN
cord-321013-8pkrg0mx	64	23	N	n	CD
cord-321013-8pkrg0mx	64	24	to	to	IN
cord-321013-8pkrg0mx	64	25	the	the	DT
cord-321013-8pkrg0mx	64	26	site	site	NN
cord-321013-8pkrg0mx	64	27	of	of	IN
cord-321013-8pkrg0mx	64	28	replication	replication	NN
cord-321013-8pkrg0mx	64	29	[	[	-LRB-
cord-321013-8pkrg0mx	64	30	50	50	CD
cord-321013-8pkrg0mx	64	31	]	]	-RRB-
cord-321013-8pkrg0mx	64	32	and/or	and/or	CC
cord-321013-8pkrg0mx	64	33	other	other	JJ
cord-321013-8pkrg0mx	64	34	RNA	RNA	NNP
cord-321013-8pkrg0mx	64	35	binding	binding	NN
cord-321013-8pkrg0mx	64	36	functions	function	NNS
cord-321013-8pkrg0mx	64	37	of	of	IN
cord-321013-8pkrg0mx	64	38	N.	N.	NNP
cord-321013-8pkrg0mx	64	39	The	the	DT
cord-321013-8pkrg0mx	64	40	CTD	CTD	NNP
cord-321013-8pkrg0mx	64	41	,	,	,
cord-321013-8pkrg0mx	64	42	which	which	WDT
cord-321013-8pkrg0mx	64	43	is	be	VBZ
cord-321013-8pkrg0mx	64	44	a	a	DT
cord-321013-8pkrg0mx	64	45	hydrophobic	hydrophobic	JJ
cord-321013-8pkrg0mx	64	46	,	,	,
cord-321013-8pkrg0mx	64	47	helix	helix	NN
cord-321013-8pkrg0mx	64	48	-	-	HYPH
cord-321013-8pkrg0mx	64	49	rich	rich	JJ
cord-321013-8pkrg0mx	64	50	terminal	terminal	NN
cord-321013-8pkrg0mx	64	51	,	,	,
cord-321013-8pkrg0mx	64	52	has	have	VBZ
cord-321013-8pkrg0mx	64	53	been	be	VBN
cord-321013-8pkrg0mx	64	54	mapped	map	VBN
cord-321013-8pkrg0mx	64	55	for	for	IN
cord-321013-8pkrg0mx	64	56	SARS	SARS	NNP
cord-321013-8pkrg0mx	64	57	-	-	HYPH
cord-321013-8pkrg0mx	64	58	N	N	NNP
cord-321013-8pkrg0mx	64	59	to	to	IN
cord-321013-8pkrg0mx	64	60	aa	aa	NNP
cord-321013-8pkrg0mx	64	61	248	248	CD
cord-321013-8pkrg0mx	64	62	-	-	HYPH
cord-321013-8pkrg0mx	64	63	365	365	CD
cord-321013-8pkrg0mx	64	64	[	[	-LRB-
cord-321013-8pkrg0mx	64	65	17	17	CD
cord-321013-8pkrg0mx	64	66	]	]	-RRB-
cord-321013-8pkrg0mx	64	67	,	,	,
cord-321013-8pkrg0mx	64	68	and	and	CC
cord-321013-8pkrg0mx	64	69	for	for	IN
cord-321013-8pkrg0mx	64	70	IBV	IBV	NNP
cord-321013-8pkrg0mx	64	71	-	-	HYPH
cord-321013-8pkrg0mx	64	72	N	N	NNP
cord-321013-8pkrg0mx	64	73	to	to	IN
cord-321013-8pkrg0mx	64	74	aa	aa	NNP
cord-321013-8pkrg0mx	64	75	219	219	CD
cord-321013-8pkrg0mx	64	76	-	-	HYPH
cord-321013-8pkrg0mx	64	77	349	349	CD
cord-321013-8pkrg0mx	64	78	[	[	-LRB-
cord-321013-8pkrg0mx	64	79	21	21	CD
cord-321013-8pkrg0mx	64	80	,	,	,
cord-321013-8pkrg0mx	64	81	53	53	CD
cord-321013-8pkrg0mx	64	82	]	]	-RRB-
cord-321013-8pkrg0mx	64	83	.	.	.
cord-321013-8pkrg0mx	65	1	This	this	DT
cord-321013-8pkrg0mx	65	2	domain	domain	NN
cord-321013-8pkrg0mx	65	3	is	be	VBZ
cord-321013-8pkrg0mx	65	4	also	also	RB
cord-321013-8pkrg0mx	65	5	referred	refer	VBN
cord-321013-8pkrg0mx	65	6	to	to	IN
cord-321013-8pkrg0mx	65	7	as	as	IN
cord-321013-8pkrg0mx	65	8	the	the	DT
cord-321013-8pkrg0mx	65	9	dimerization	dimerization	NN
cord-321013-8pkrg0mx	65	10	domain	domain	NN
cord-321013-8pkrg0mx	65	11	because	because	IN
cord-321013-8pkrg0mx	65	12	it	-PRON-	PRP
cord-321013-8pkrg0mx	65	13	contains	contain	VBZ
cord-321013-8pkrg0mx	65	14	residues	residue	NNS
cord-321013-8pkrg0mx	65	15	responsible	responsible	JJ
cord-321013-8pkrg0mx	65	16	for	for	IN
cord-321013-8pkrg0mx	65	17	self	self	NN
cord-321013-8pkrg0mx	65	18	-	-	HYPH
cord-321013-8pkrg0mx	65	19	association	association	NN
cord-321013-8pkrg0mx	65	20	to	to	TO
cord-321013-8pkrg0mx	65	21	form	form	VB
cord-321013-8pkrg0mx	65	22	homodimers	homodimer	NNS
cord-321013-8pkrg0mx	65	23	,	,	,
cord-321013-8pkrg0mx	65	24	as	as	RB
cord-321013-8pkrg0mx	65	25	well	well	RB
cord-321013-8pkrg0mx	65	26	as	as	IN
cord-321013-8pkrg0mx	65	27	homo	homo	NN
cord-321013-8pkrg0mx	65	28	-	-	HYPH
cord-321013-8pkrg0mx	65	29	oligomers	oligomer	NNS
cord-321013-8pkrg0mx	65	30	through	through	IN
cord-321013-8pkrg0mx	65	31	a	a	DT
cord-321013-8pkrg0mx	65	32	domain	domain	NN
cord-321013-8pkrg0mx	65	33	-	-	HYPH
cord-321013-8pkrg0mx	65	34	swapping	swapping	NN
cord-321013-8pkrg0mx	65	35	mechanism	mechanism	NN
cord-321013-8pkrg0mx	65	36	[	[	-LRB-
cord-321013-8pkrg0mx	65	37	16	16	CD
cord-321013-8pkrg0mx	65	38	,	,	,
cord-321013-8pkrg0mx	65	39	17	17	CD
cord-321013-8pkrg0mx	65	40	,	,	,
cord-321013-8pkrg0mx	65	41	42	42	CD
cord-321013-8pkrg0mx	65	42	,	,	,
cord-321013-8pkrg0mx	65	43	[	[	-LRB-
cord-321013-8pkrg0mx	65	44	53	53	CD
cord-321013-8pkrg0mx	65	45	]	]	-RRB-
cord-321013-8pkrg0mx	65	46	[	[	-LRB-
cord-321013-8pkrg0mx	65	47	54	54	CD
cord-321013-8pkrg0mx	65	48	]	]	-RRB-
cord-321013-8pkrg0mx	65	49	[	[	-LRB-
cord-321013-8pkrg0mx	65	50	55	55	CD
cord-321013-8pkrg0mx	65	51	]	]	-RRB-
cord-321013-8pkrg0mx	65	52	[	[	-LRB-
cord-321013-8pkrg0mx	65	53	56	56	CD
cord-321013-8pkrg0mx	65	54	]	]	-RRB-
cord-321013-8pkrg0mx	65	55	[	[	-LRB-
cord-321013-8pkrg0mx	65	56	57	57	CD
cord-321013-8pkrg0mx	65	57	]	]	-RRB-
cord-321013-8pkrg0mx	65	58	.	.	.
cord-321013-8pkrg0mx	66	1	Oligomerization	Oligomerization	NNP
cord-321013-8pkrg0mx	66	2	of	of	IN
cord-321013-8pkrg0mx	66	3	N	n	CD
cord-321013-8pkrg0mx	66	4	protein	protein	NN
cord-321013-8pkrg0mx	66	5	is	be	VBZ
cord-321013-8pkrg0mx	66	6	necessary	necessary	JJ
cord-321013-8pkrg0mx	66	7	to	to	TO
cord-321013-8pkrg0mx	66	8	produce	produce	VB
cord-321013-8pkrg0mx	66	9	a	a	DT
cord-321013-8pkrg0mx	66	10	stable	stable	JJ
cord-321013-8pkrg0mx	66	11	conformation	conformation	NN
cord-321013-8pkrg0mx	66	12	because	because	IN
cord-321013-8pkrg0mx	66	13	in	in	IN
cord-321013-8pkrg0mx	66	14	its	-PRON-	PRP$
cord-321013-8pkrg0mx	66	15	monomeric	monomeric	JJ
cord-321013-8pkrg0mx	66	16	form	form	NN
cord-321013-8pkrg0mx	66	17	,	,	,
cord-321013-8pkrg0mx	66	18	the	the	DT
cord-321013-8pkrg0mx	66	19	CTD	CTD	NNP
cord-321013-8pkrg0mx	66	20	folds	fold	VBZ
cord-321013-8pkrg0mx	66	21	into	into	IN
cord-321013-8pkrg0mx	66	22	an	an	DT
cord-321013-8pkrg0mx	66	23	extended	extended	JJ
cord-321013-8pkrg0mx	66	24	conformation	conformation	NN
cord-321013-8pkrg0mx	66	25	with	with	IN
cord-321013-8pkrg0mx	66	26	a	a	DT
cord-321013-8pkrg0mx	66	27	large	large	JJ
cord-321013-8pkrg0mx	66	28	cavity	cavity	NN
cord-321013-8pkrg0mx	66	29	in	in	IN
cord-321013-8pkrg0mx	66	30	its	-PRON-	PRP$
cord-321013-8pkrg0mx	66	31	center	center	NN
cord-321013-8pkrg0mx	66	32	,	,	,
cord-321013-8pkrg0mx	66	33	making	make	VBG
cord-321013-8pkrg0mx	66	34	it	-PRON-	PRP
cord-321013-8pkrg0mx	66	35	unstable	unstable	JJ
cord-321013-8pkrg0mx	66	36	[	[	-LRB-
cord-321013-8pkrg0mx	66	37	47	47	CD
cord-321013-8pkrg0mx	66	38	]	]	-RRB-
cord-321013-8pkrg0mx	66	39	.	.	.
cord-321013-8pkrg0mx	67	1	Sequence	sequence	NN
cord-321013-8pkrg0mx	67	2	comparison	comparison	NN
cord-321013-8pkrg0mx	67	3	shows	show	VBZ
cord-321013-8pkrg0mx	67	4	that	that	IN
cord-321013-8pkrg0mx	67	5	the	the	DT
cord-321013-8pkrg0mx	67	6	dimerization	dimerization	NN
cord-321013-8pkrg0mx	67	7	domain	domain	NN
cord-321013-8pkrg0mx	67	8	of	of	IN
cord-321013-8pkrg0mx	67	9	the	the	DT
cord-321013-8pkrg0mx	67	10	N	N	NNP
cord-321013-8pkrg0mx	67	11	protein	protein	NN
cord-321013-8pkrg0mx	67	12	is	be	VBZ
cord-321013-8pkrg0mx	67	13	conserved	conserve	VBN
cord-321013-8pkrg0mx	67	14	at	at	IN
cord-321013-8pkrg0mx	67	15	least	least	JJS
cord-321013-8pkrg0mx	67	16	among	among	IN
cord-321013-8pkrg0mx	67	17	the	the	DT
cord-321013-8pkrg0mx	67	18	alpha	alpha	NN
cord-321013-8pkrg0mx	67	19	,	,	,
cord-321013-8pkrg0mx	67	20	beta	beta	NN
cord-321013-8pkrg0mx	67	21	and	and	CC
cord-321013-8pkrg0mx	67	22	gamma	gamma	NN
cord-321013-8pkrg0mx	67	23	groups	group	NNS
cord-321013-8pkrg0mx	67	24	of	of	IN
cord-321013-8pkrg0mx	67	25	CoVs	CoVs	NNP
cord-321013-8pkrg0mx	67	26	,	,	,
cord-321013-8pkrg0mx	67	27	suggesting	suggest	VBG
cord-321013-8pkrg0mx	67	28	a	a	DT
cord-321013-8pkrg0mx	67	29	common	common	JJ
cord-321013-8pkrg0mx	67	30	structural	structural	JJ
cord-321013-8pkrg0mx	67	31	and	and	CC
cord-321013-8pkrg0mx	67	32	functional	functional	JJ
cord-321013-8pkrg0mx	67	33	role	role	NN
cord-321013-8pkrg0mx	67	34	for	for	IN
cord-321013-8pkrg0mx	67	35	this	this	DT
cord-321013-8pkrg0mx	67	36	domain	domain	NN
cord-321013-8pkrg0mx	67	37	[	[	-LRB-
cord-321013-8pkrg0mx	67	38	47	47	CD
cord-321013-8pkrg0mx	67	39	]	]	-RRB-
cord-321013-8pkrg0mx	67	40	.	.	.
cord-321013-8pkrg0mx	68	1	The	the	DT
cord-321013-8pkrg0mx	68	2	monomer	monomer	NN
cord-321013-8pkrg0mx	68	3	of	of	IN
cord-321013-8pkrg0mx	68	4	cSARS	cSARS	NNP
cord-321013-8pkrg0mx	68	5	-	-	HYPH
cord-321013-8pkrg0mx	68	6	N	N	NNP
cord-321013-8pkrg0mx	68	7	,	,	,
cord-321013-8pkrg0mx	68	8	a	a	DT
cord-321013-8pkrg0mx	68	9	crystalized	crystalize	VBN
cord-321013-8pkrg0mx	68	10	C	c	NN
cord-321013-8pkrg0mx	68	11	-	-	HYPH
cord-321013-8pkrg0mx	68	12	terminal	terminal	NN
cord-321013-8pkrg0mx	68	13	construct	construct	NN
cord-321013-8pkrg0mx	68	14	of	of	IN
cord-321013-8pkrg0mx	68	15	SARS	SARS	NNP
cord-321013-8pkrg0mx	68	16	-	-	HYPH
cord-321013-8pkrg0mx	68	17	N	N	NNP
cord-321013-8pkrg0mx	68	18	that	that	WDT
cord-321013-8pkrg0mx	68	19	contains	contain	VBZ
cord-321013-8pkrg0mx	68	20	residues	residue	NNS
cord-321013-8pkrg0mx	68	21	270	270	CD
cord-321013-8pkrg0mx	68	22	-	-	SYM
cord-321013-8pkrg0mx	68	23	370	370	CD
cord-321013-8pkrg0mx	68	24	,	,	,
cord-321013-8pkrg0mx	68	25	comprises	comprise	VBZ
cord-321013-8pkrg0mx	68	26	five	five	CD
cord-321013-8pkrg0mx	68	27	short	short	JJ
cord-321013-8pkrg0mx	68	28	α	α	NN
cord-321013-8pkrg0mx	68	29	-	-	HYPH
cord-321013-8pkrg0mx	68	30	helices	helix	NNS
cord-321013-8pkrg0mx	68	31	,	,	,
cord-321013-8pkrg0mx	68	32	one	one	CD
cord-321013-8pkrg0mx	68	33	3	3	CD
cord-321013-8pkrg0mx	68	34	10	10	CD
cord-321013-8pkrg0mx	68	35	helix	helix	NN
cord-321013-8pkrg0mx	68	36	,	,	,
cord-321013-8pkrg0mx	68	37	and	and	CC
cord-321013-8pkrg0mx	68	38	two	two	CD
cord-321013-8pkrg0mx	68	39	β	β	NN
cord-321013-8pkrg0mx	68	40	-	-	HYPH
cord-321013-8pkrg0mx	68	41	strands	strand	NNS
cord-321013-8pkrg0mx	68	42	[	[	-LRB-
cord-321013-8pkrg0mx	68	43	47	47	CD
cord-321013-8pkrg0mx	68	44	]	]	-RRB-
cord-321013-8pkrg0mx	68	45	.	.	.
cord-321013-8pkrg0mx	69	1	The	the	DT
cord-321013-8pkrg0mx	69	2	general	general	JJ
cord-321013-8pkrg0mx	69	3	shape	shape	NN
cord-321013-8pkrg0mx	69	4	of	of	IN
cord-321013-8pkrg0mx	69	5	the	the	DT
cord-321013-8pkrg0mx	69	6	monomer	monomer	NN
cord-321013-8pkrg0mx	69	7	resembles	resemble	VBZ
cord-321013-8pkrg0mx	69	8	the	the	DT
cord-321013-8pkrg0mx	69	9	letter	letter	NN
cord-321013-8pkrg0mx	69	10	C	C	NNP
cord-321013-8pkrg0mx	69	11	,	,	,
cord-321013-8pkrg0mx	69	12	with	with	IN
cord-321013-8pkrg0mx	69	13	one	one	CD
cord-321013-8pkrg0mx	69	14	edge	edge	NN
cord-321013-8pkrg0mx	69	15	formed	form	VBN
cord-321013-8pkrg0mx	69	16	by	by	IN
cord-321013-8pkrg0mx	69	17	a	a	DT
cord-321013-8pkrg0mx	69	18	β	β	NN
cord-321013-8pkrg0mx	69	19	-	-	HYPH
cord-321013-8pkrg0mx	69	20	hairpin	hairpin	NN
cord-321013-8pkrg0mx	69	21	extending	extend	VBG
cord-321013-8pkrg0mx	69	22	away	away	RB
cord-321013-8pkrg0mx	69	23	from	from	IN
cord-321013-8pkrg0mx	69	24	the	the	DT
cord-321013-8pkrg0mx	69	25	rest	rest	NN
cord-321013-8pkrg0mx	69	26	of	of	IN
cord-321013-8pkrg0mx	69	27	the	the	DT
cord-321013-8pkrg0mx	69	28	molecule	molecule	NN
cord-321013-8pkrg0mx	69	29	[	[	-LRB-
cord-321013-8pkrg0mx	69	30	47	47	CD
cord-321013-8pkrg0mx	69	31	]	]	-RRB-
cord-321013-8pkrg0mx	69	32	.	.	.
cord-321013-8pkrg0mx	70	1	This	this	DT
cord-321013-8pkrg0mx	70	2	structure	structure	NN
cord-321013-8pkrg0mx	70	3	is	be	VBZ
cord-321013-8pkrg0mx	70	4	similar	similar	JJ
cord-321013-8pkrg0mx	70	5	to	to	IN
cord-321013-8pkrg0mx	70	6	the	the	DT
cord-321013-8pkrg0mx	70	7	crystalline	crystalline	JJ
cord-321013-8pkrg0mx	70	8	structure	structure	NN
cord-321013-8pkrg0mx	70	9	of	of	IN
cord-321013-8pkrg0mx	70	10	another	another	DT
cord-321013-8pkrg0mx	70	11	SARS	SARS	NNP
cord-321013-8pkrg0mx	70	12	N	N	NNP
cord-321013-8pkrg0mx	70	13	CTD	CTD	NNP
cord-321013-8pkrg0mx	70	14	monomer	monomer	NN
cord-321013-8pkrg0mx	70	15	(	(	-LRB-
cord-321013-8pkrg0mx	70	16	NP248	NP248	NNP
cord-321013-8pkrg0mx	70	17	-	-	HYPH
cord-321013-8pkrg0mx	70	18	365	365	CD
cord-321013-8pkrg0mx	70	19	)	)	-RRB-
cord-321013-8pkrg0mx	70	20	,	,	,
cord-321013-8pkrg0mx	70	21	which	which	WDT
cord-321013-8pkrg0mx	70	22	consists	consist	VBZ
cord-321013-8pkrg0mx	70	23	of	of	IN
cord-321013-8pkrg0mx	70	24	eight	eight	CD
cord-321013-8pkrg0mx	70	25	α	α	NN
cord-321013-8pkrg0mx	70	26	-	-	HYPH
cord-321013-8pkrg0mx	70	27	helices	helix	NNS
cord-321013-8pkrg0mx	70	28	and	and	CC
cord-321013-8pkrg0mx	70	29	two	two	CD
cord-321013-8pkrg0mx	70	30	β	β	NN
cord-321013-8pkrg0mx	70	31	-	-	HYPH
cord-321013-8pkrg0mx	70	32	strands	strand	NNS
cord-321013-8pkrg0mx	70	33	[	[	-LRB-
cord-321013-8pkrg0mx	70	34	55	55	CD
cord-321013-8pkrg0mx	70	35	]	]	-RRB-
cord-321013-8pkrg0mx	70	36	.	.	.
cord-321013-8pkrg0mx	71	1	The	the	DT
cord-321013-8pkrg0mx	71	2	cSARS	cSARS	NNP
cord-321013-8pkrg0mx	71	3	-	-	HYPH
cord-321013-8pkrg0mx	71	4	N	n	CD
cord-321013-8pkrg0mx	71	5	dimer	dimer	NN
cord-321013-8pkrg0mx	71	6	interface	interface	NN
cord-321013-8pkrg0mx	71	7	is	be	VBZ
cord-321013-8pkrg0mx	71	8	formed	form	VBN
cord-321013-8pkrg0mx	71	9	largely	largely	RB
cord-321013-8pkrg0mx	71	10	by	by	IN
cord-321013-8pkrg0mx	71	11	insertion	insertion	NN
cord-321013-8pkrg0mx	71	12	of	of	IN
cord-321013-8pkrg0mx	71	13	the	the	DT
cord-321013-8pkrg0mx	71	14	β	β	NN
cord-321013-8pkrg0mx	71	15	-	-	HYPH
cord-321013-8pkrg0mx	71	16	hairpin	hairpin	NNP
cord-321013-8pkrg0mx	71	17	of	of	IN
cord-321013-8pkrg0mx	71	18	one	one	CD
cord-321013-8pkrg0mx	71	19	subunit	subunit	NN
cord-321013-8pkrg0mx	71	20	into	into	IN
cord-321013-8pkrg0mx	71	21	the	the	DT
cord-321013-8pkrg0mx	71	22	cavity	cavity	NN
cord-321013-8pkrg0mx	71	23	of	of	IN
cord-321013-8pkrg0mx	71	24	the	the	DT
cord-321013-8pkrg0mx	71	25	opposite	opposite	JJ
cord-321013-8pkrg0mx	71	26	subunit	subunit	NN
cord-321013-8pkrg0mx	71	27	,	,	,
cord-321013-8pkrg0mx	71	28	resulting	result	VBG
cord-321013-8pkrg0mx	71	29	in	in	IN
cord-321013-8pkrg0mx	71	30	the	the	DT
cord-321013-8pkrg0mx	71	31	four	four	CD
cord-321013-8pkrg0mx	71	32	β	β	NN
cord-321013-8pkrg0mx	71	33	-	-	HYPH
cord-321013-8pkrg0mx	71	34	strands	strand	NNS
cord-321013-8pkrg0mx	71	35	of	of	IN
cord-321013-8pkrg0mx	71	36	the	the	DT
cord-321013-8pkrg0mx	71	37	two	two	CD
cord-321013-8pkrg0mx	71	38	subunits	subunit	NNS
cord-321013-8pkrg0mx	71	39	forming	form	VBG
cord-321013-8pkrg0mx	71	40	an	an	DT
cord-321013-8pkrg0mx	71	41	anti	anti	JJ
cord-321013-8pkrg0mx	71	42	-	-	JJ
cord-321013-8pkrg0mx	71	43	parallel	parallel	JJ
cord-321013-8pkrg0mx	71	44	β	β	NN
cord-321013-8pkrg0mx	71	45	-	-	HYPH
cord-321013-8pkrg0mx	71	46	sheet	sheet	NN
cord-321013-8pkrg0mx	71	47	that	that	WDT
cord-321013-8pkrg0mx	71	48	is	be	VBZ
cord-321013-8pkrg0mx	71	49	superposed	superpose	VBN
cord-321013-8pkrg0mx	71	50	by	by	IN
cord-321013-8pkrg0mx	71	51	two	two	CD
cord-321013-8pkrg0mx	71	52	long	long	JJ
cord-321013-8pkrg0mx	71	53	alpha	alpha	NN
cord-321013-8pkrg0mx	71	54	helices	helix	NNS
cord-321013-8pkrg0mx	71	55	[	[	-LRB-
cord-321013-8pkrg0mx	71	56	47	47	CD
cord-321013-8pkrg0mx	71	57	]	]	-RRB-
cord-321013-8pkrg0mx	71	58	.	.	.
cord-321013-8pkrg0mx	72	1	Due	due	IN
cord-321013-8pkrg0mx	72	2	to	to	IN
cord-321013-8pkrg0mx	72	3	the	the	DT
cord-321013-8pkrg0mx	72	4	extensive	extensive	JJ
cord-321013-8pkrg0mx	72	5	hydrogen	hydrogen	NN
cord-321013-8pkrg0mx	72	6	bond	bond	NN
cord-321013-8pkrg0mx	72	7	formation	formation	NN
cord-321013-8pkrg0mx	72	8	between	between	IN
cord-321013-8pkrg0mx	72	9	the	the	DT
cord-321013-8pkrg0mx	72	10	two	two	CD
cord-321013-8pkrg0mx	72	11	hairpins	hairpin	NNS
cord-321013-8pkrg0mx	72	12	,	,	,
cord-321013-8pkrg0mx	72	13	together	together	RB
cord-321013-8pkrg0mx	72	14	with	with	IN
cord-321013-8pkrg0mx	72	15	hydrophobic	hydrophobic	JJ
cord-321013-8pkrg0mx	72	16	interactions	interaction	NNS
cord-321013-8pkrg0mx	72	17	between	between	IN
cord-321013-8pkrg0mx	72	18	the	the	DT
cord-321013-8pkrg0mx	72	19	beta	beta	NN
cord-321013-8pkrg0mx	72	20	-	-	HYPH
cord-321013-8pkrg0mx	72	21	sheet	sheet	NN
cord-321013-8pkrg0mx	72	22	and	and	CC
cord-321013-8pkrg0mx	72	23	the	the	DT
cord-321013-8pkrg0mx	72	24	alpha	alpha	NN
cord-321013-8pkrg0mx	72	25	helices	helix	NNS
cord-321013-8pkrg0mx	72	26	,	,	,
cord-321013-8pkrg0mx	72	27	this	this	DT
cord-321013-8pkrg0mx	72	28	interface	interface	NN
cord-321013-8pkrg0mx	72	29	is	be	VBZ
cord-321013-8pkrg0mx	72	30	highly	highly	RB
cord-321013-8pkrg0mx	72	31	stable	stable	JJ
cord-321013-8pkrg0mx	72	32	[	[	-LRB-
cord-321013-8pkrg0mx	72	33	17	17	CD
cord-321013-8pkrg0mx	72	34	]	]	-RRB-
cord-321013-8pkrg0mx	72	35	,	,	,
cord-321013-8pkrg0mx	72	36	and	and	CC
cord-321013-8pkrg0mx	72	37	these	these	DT
cord-321013-8pkrg0mx	72	38	interactions	interaction	NNS
cord-321013-8pkrg0mx	72	39	suggests	suggest	VBZ
cord-321013-8pkrg0mx	72	40	that	that	IN
cord-321013-8pkrg0mx	72	41	the	the	DT
cord-321013-8pkrg0mx	72	42	dimeric	dimeric	JJ
cord-321013-8pkrg0mx	72	43	structure	structure	NN
cord-321013-8pkrg0mx	72	44	may	may	MD
cord-321013-8pkrg0mx	72	45	in	in	IN
cord-321013-8pkrg0mx	72	46	fact	fact	NN
cord-321013-8pkrg0mx	72	47	represent	represent	VB
cord-321013-8pkrg0mx	72	48	the	the	DT
cord-321013-8pkrg0mx	72	49	functional	functional	JJ
cord-321013-8pkrg0mx	72	50	unit	unit	NN
cord-321013-8pkrg0mx	72	51	of	of	IN
cord-321013-8pkrg0mx	72	52	the	the	DT
cord-321013-8pkrg0mx	72	53	N	N	NNP
cord-321013-8pkrg0mx	72	54	protein	protein	NN
cord-321013-8pkrg0mx	72	55	[	[	-LRB-
cord-321013-8pkrg0mx	72	56	47	47	CD
cord-321013-8pkrg0mx	72	57	]	]	-RRB-
cord-321013-8pkrg0mx	72	58	.	.	.
cord-321013-8pkrg0mx	73	1	The	the	DT
cord-321013-8pkrg0mx	73	2	crystal	crystal	JJ
cord-321013-8pkrg0mx	73	3	structure	structure	NN
cord-321013-8pkrg0mx	73	4	of	of	IN
cord-321013-8pkrg0mx	73	5	NP248	NP248	NNP
cord-321013-8pkrg0mx	73	6	-	-	HYPH
cord-321013-8pkrg0mx	73	7	365	365	CD
cord-321013-8pkrg0mx	73	8	,	,	,
cord-321013-8pkrg0mx	73	9	a	a	DT
cord-321013-8pkrg0mx	73	10	SARS	SARS	NNP
cord-321013-8pkrg0mx	73	11	-	-	HYPH
cord-321013-8pkrg0mx	73	12	CoV	CoV	NNP
cord-321013-8pkrg0mx	73	13	CTD	CTD	NNP
cord-321013-8pkrg0mx	73	14	spanning	span	VBG
cord-321013-8pkrg0mx	73	15	residues	residue	NNS
cord-321013-8pkrg0mx	73	16	248	248	CD
cord-321013-8pkrg0mx	73	17	-	-	HYPH
cord-321013-8pkrg0mx	73	18	365	365	CD
cord-321013-8pkrg0mx	73	19	,	,	,
cord-321013-8pkrg0mx	73	20	revealed	reveal	VBD
cord-321013-8pkrg0mx	73	21	that	that	IN
cord-321013-8pkrg0mx	73	22	the	the	DT
cord-321013-8pkrg0mx	73	23	N	N	NNP
cord-321013-8pkrg0mx	73	24	protein	protein	NN
cord-321013-8pkrg0mx	73	25	dimer	dimer	NN
cord-321013-8pkrg0mx	73	26	has	have	VBZ
cord-321013-8pkrg0mx	73	27	the	the	DT
cord-321013-8pkrg0mx	73	28	shape	shape	NN
cord-321013-8pkrg0mx	73	29	of	of	IN
cord-321013-8pkrg0mx	73	30	a	a	DT
cord-321013-8pkrg0mx	73	31	rectangular	rectangular	JJ
cord-321013-8pkrg0mx	73	32	slab	slab	NN
cord-321013-8pkrg0mx	73	33	in	in	IN
cord-321013-8pkrg0mx	73	34	which	which	WDT
cord-321013-8pkrg0mx	73	35	the	the	DT
cord-321013-8pkrg0mx	73	36	four	four	CD
cord-321013-8pkrg0mx	73	37	-	-	HYPH
cord-321013-8pkrg0mx	73	38	stranded	strand	VBN
cord-321013-8pkrg0mx	73	39	β	β	NN
cord-321013-8pkrg0mx	73	40	-	-	HYPH
cord-321013-8pkrg0mx	73	41	sheet	sheet	NN
cord-321013-8pkrg0mx	73	42	forms	form	NNS
cord-321013-8pkrg0mx	73	43	one	one	CD
cord-321013-8pkrg0mx	73	44	face	face	NN
cord-321013-8pkrg0mx	73	45	of	of	IN
cord-321013-8pkrg0mx	73	46	the	the	DT
cord-321013-8pkrg0mx	73	47	slab	slab	NN
cord-321013-8pkrg0mx	73	48	and	and	CC
cord-321013-8pkrg0mx	73	49	the	the	DT
cord-321013-8pkrg0mx	73	50	α	α	NN
cord-321013-8pkrg0mx	73	51	-	-	HYPH
cord-321013-8pkrg0mx	73	52	helices	helix	NNS
cord-321013-8pkrg0mx	73	53	form	form	VBP
cord-321013-8pkrg0mx	73	54	the	the	DT
cord-321013-8pkrg0mx	73	55	opposite	opposite	JJ
cord-321013-8pkrg0mx	73	56	face	face	NN
cord-321013-8pkrg0mx	73	57	[	[	-LRB-
cord-321013-8pkrg0mx	73	58	55	55	CD
cord-321013-8pkrg0mx	73	59	]	]	-RRB-
cord-321013-8pkrg0mx	73	60	.	.	.
cord-321013-8pkrg0mx	74	1	Similarly	similarly	RB
cord-321013-8pkrg0mx	74	2	to	to	IN
cord-321013-8pkrg0mx	74	3	cSARS	cSARS	NNP
cord-321013-8pkrg0mx	74	4	N	n	CD
cord-321013-8pkrg0mx	74	5	,	,	,
cord-321013-8pkrg0mx	74	6	the	the	DT
cord-321013-8pkrg0mx	74	7	dimerization	dimerization	NN
cord-321013-8pkrg0mx	74	8	interface	interface	NN
cord-321013-8pkrg0mx	74	9	of	of	IN
cord-321013-8pkrg0mx	74	10	NP248	NP248	NNP
cord-321013-8pkrg0mx	74	11	-	-	HYPH
cord-321013-8pkrg0mx	74	12	365	365	CD
cord-321013-8pkrg0mx	74	13	is	be	VBZ
cord-321013-8pkrg0mx	74	14	composed	compose	VBN
cord-321013-8pkrg0mx	74	15	of	of	IN
cord-321013-8pkrg0mx	74	16	four	four	CD
cord-321013-8pkrg0mx	74	17	β	β	NN
cord-321013-8pkrg0mx	74	18	-	-	HYPH
cord-321013-8pkrg0mx	74	19	strands	strand	NNS
cord-321013-8pkrg0mx	74	20	and	and	CC
cord-321013-8pkrg0mx	74	21	six	six	CD
cord-321013-8pkrg0mx	74	22	α	α	NN
cord-321013-8pkrg0mx	74	23	-	-	HYPH
cord-321013-8pkrg0mx	74	24	helices	helix	NNS
cord-321013-8pkrg0mx	74	25	,	,	,
cord-321013-8pkrg0mx	74	26	with	with	IN
cord-321013-8pkrg0mx	74	27	each	each	DT
cord-321013-8pkrg0mx	74	28	protomer	protomer	NN
cord-321013-8pkrg0mx	74	29	contributing	contribute	VBG
cord-321013-8pkrg0mx	74	30	one	one	CD
cord-321013-8pkrg0mx	74	31	β	β	NN
cord-321013-8pkrg0mx	74	32	-	-	HYPH
cord-321013-8pkrg0mx	74	33	hairpin	hairpin	NNP
cord-321013-8pkrg0mx	74	34	and	and	CC
cord-321013-8pkrg0mx	74	35	helices	helix	NNS
cord-321013-8pkrg0mx	74	36	α5	α5	NNP
cord-321013-8pkrg0mx	74	37	,	,	,
cord-321013-8pkrg0mx	74	38	α6	α6	FW
cord-321013-8pkrg0mx	74	39	and	and	CC
cord-321013-8pkrg0mx	74	40	α7	α7	NN
cord-321013-8pkrg0mx	74	41	.	.	.
cord-321013-8pkrg0mx	75	1	The	the	DT
cord-321013-8pkrg0mx	75	2	two	two	CD
cord-321013-8pkrg0mx	75	3	β	β	NN
cord-321013-8pkrg0mx	75	4	-	-	HYPH
cord-321013-8pkrg0mx	75	5	hairpins	hairpin	NNS
cord-321013-8pkrg0mx	75	6	form	form	VBP
cord-321013-8pkrg0mx	75	7	a	a	DT
cord-321013-8pkrg0mx	75	8	four	four	CD
cord-321013-8pkrg0mx	75	9	-	-	HYPH
cord-321013-8pkrg0mx	75	10	stranded	stranded	JJ
cord-321013-8pkrg0mx	75	11	intermolecular	intermolecular	JJ
cord-321013-8pkrg0mx	75	12	β	β	NN
cord-321013-8pkrg0mx	75	13	-	-	HYPH
cord-321013-8pkrg0mx	75	14	sheet	sheet	NN
cord-321013-8pkrg0mx	75	15	that	that	WDT
cord-321013-8pkrg0mx	75	16	is	be	VBZ
cord-321013-8pkrg0mx	75	17	stabilized	stabilize	VBN
cord-321013-8pkrg0mx	75	18	through	through	IN
cord-321013-8pkrg0mx	75	19	extensive	extensive	JJ
cord-321013-8pkrg0mx	75	20	hydrogen	hydrogen	NN
cord-321013-8pkrg0mx	75	21	bonding	bonding	NN
cord-321013-8pkrg0mx	75	22	.	.	.
cord-321013-8pkrg0mx	76	1	The	the	DT
cord-321013-8pkrg0mx	76	2	other	other	JJ
cord-321013-8pkrg0mx	76	3	part	part	NN
cord-321013-8pkrg0mx	76	4	of	of	IN
cord-321013-8pkrg0mx	76	5	the	the	DT
cord-321013-8pkrg0mx	76	6	dimerization	dimerization	NN
cord-321013-8pkrg0mx	76	7	interface	interface	NN
cord-321013-8pkrg0mx	76	8	is	be	VBZ
cord-321013-8pkrg0mx	76	9	composed	compose	VBN
cord-321013-8pkrg0mx	76	10	of	of	IN
cord-321013-8pkrg0mx	76	11	helices	helix	NNS
cord-321013-8pkrg0mx	76	12	α5	α5	NNP
cord-321013-8pkrg0mx	76	13	and	and	CC
cord-321013-8pkrg0mx	76	14	α6	α6	NNP
cord-321013-8pkrg0mx	76	15	,	,	,
cord-321013-8pkrg0mx	76	16	where	where	WRB
cord-321013-8pkrg0mx	76	17	strong	strong	JJ
cord-321013-8pkrg0mx	76	18	hydrophobic	hydrophobic	JJ
cord-321013-8pkrg0mx	76	19	interactions	interaction	NNS
cord-321013-8pkrg0mx	76	20	involving	involve	VBG
cord-321013-8pkrg0mx	76	21	Trp302	trp302	CD
cord-321013-8pkrg0mx	76	22	,	,	,
cord-321013-8pkrg0mx	76	23	Ile305	ile305	CD
cord-321013-8pkrg0mx	76	24	,	,	,
cord-321013-8pkrg0mx	76	25	Pro310	pro310	CD
cord-321013-8pkrg0mx	76	26	,	,	,
cord-321013-8pkrg0mx	76	27	Phe315	Phe315	NNP
cord-321013-8pkrg0mx	76	28	and	and	CC
cord-321013-8pkrg0mx	76	29	Phe316	Phe316	NNP
cord-321013-8pkrg0mx	76	30	were	be	VBD
cord-321013-8pkrg0mx	76	31	observed	observe	VBN
cord-321013-8pkrg0mx	76	32	.	.	.
cord-321013-8pkrg0mx	77	1	The	the	DT
cord-321013-8pkrg0mx	77	2	dimer	dimer	NN
cord-321013-8pkrg0mx	77	3	is	be	VBZ
cord-321013-8pkrg0mx	77	4	further	further	RB
cord-321013-8pkrg0mx	77	5	stabilized	stabilize	VBN
cord-321013-8pkrg0mx	77	6	by	by	IN
cord-321013-8pkrg0mx	77	7	hydrophobic	hydrophobic	JJ
cord-321013-8pkrg0mx	77	8	interactions	interaction	NNS
cord-321013-8pkrg0mx	77	9	between	between	IN
cord-321013-8pkrg0mx	77	10	the	the	DT
cord-321013-8pkrg0mx	77	11	longest	long	JJS
cord-321013-8pkrg0mx	77	12	helix	helix	NN
cord-321013-8pkrg0mx	77	13	,	,	,
cord-321013-8pkrg0mx	77	14	α7	α7	NN
cord-321013-8pkrg0mx	77	15	,	,	,
cord-321013-8pkrg0mx	77	16	and	and	CC
cord-321013-8pkrg0mx	77	17	the	the	DT
cord-321013-8pkrg0mx	77	18	intermolecular	intermolecular	NNP
cord-321013-8pkrg0mx	77	19	β	β	NN
cord-321013-8pkrg0mx	77	20	-	-	HYPH
cord-321013-8pkrg0mx	77	21	sheet	sheet	NN
cord-321013-8pkrg0mx	77	22	[	[	-LRB-
cord-321013-8pkrg0mx	77	23	55	55	CD
cord-321013-8pkrg0mx	77	24	]	]	-RRB-
cord-321013-8pkrg0mx	77	25	.	.	.
cord-321013-8pkrg0mx	78	1	Similarly	similarly	RB
cord-321013-8pkrg0mx	78	2	to	to	IN
cord-321013-8pkrg0mx	78	3	cSARS	cSARS	NNP
cord-321013-8pkrg0mx	78	4	-	-	HYPH
cord-321013-8pkrg0mx	78	5	N	N	NNP
cord-321013-8pkrg0mx	78	6	and	and	CC
cord-321013-8pkrg0mx	78	7	NP248	NP248	NNP
cord-321013-8pkrg0mx	78	8	-	-	HYPH
cord-321013-8pkrg0mx	78	9	365	365	CD
cord-321013-8pkrg0mx	78	10	,	,	,
cord-321013-8pkrg0mx	78	11	a	a	DT
cord-321013-8pkrg0mx	78	12	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	78	13	magnetic	magnetic	JJ
cord-321013-8pkrg0mx	78	14	resonance	resonance	NN
cord-321013-8pkrg0mx	78	15	(	(	-LRB-
cord-321013-8pkrg0mx	78	16	NMR	NMR	NNP
cord-321013-8pkrg0mx	78	17	)	)	-RRB-
cord-321013-8pkrg0mx	78	18	study	study	NN
cord-321013-8pkrg0mx	78	19	has	have	VBZ
cord-321013-8pkrg0mx	78	20	reported	report	VBN
cord-321013-8pkrg0mx	78	21	secondary	secondary	JJ
cord-321013-8pkrg0mx	78	22	structural	structural	JJ
cord-321013-8pkrg0mx	78	23	assignments	assignment	NNS
cord-321013-8pkrg0mx	78	24	of	of	IN
cord-321013-8pkrg0mx	78	25	a	a	DT
cord-321013-8pkrg0mx	78	26	SARS	SARS	NNP
cord-321013-8pkrg0mx	78	27	N	N	NNP
cord-321013-8pkrg0mx	78	28	protein	protein	NN
cord-321013-8pkrg0mx	78	29	construct	construct	VBP
cord-321013-8pkrg0mx	78	30	whose	whose	WP$
cord-321013-8pkrg0mx	78	31	dimeric	dimeric	JJ
cord-321013-8pkrg0mx	78	32	interface	interface	NN
cord-321013-8pkrg0mx	78	33	also	also	RB
cord-321013-8pkrg0mx	78	34	consists	consist	VBZ
cord-321013-8pkrg0mx	78	35	of	of	IN
cord-321013-8pkrg0mx	78	36	a	a	DT
cord-321013-8pkrg0mx	78	37	four	four	CD
cord-321013-8pkrg0mx	78	38	-	-	HYPH
cord-321013-8pkrg0mx	78	39	stranded	strand	VBN
cord-321013-8pkrg0mx	78	40	anti	anti	JJ
cord-321013-8pkrg0mx	78	41	-	-	JJ
cord-321013-8pkrg0mx	78	42	parallel	parallel	JJ
cord-321013-8pkrg0mx	78	43	β	β	NN
cord-321013-8pkrg0mx	78	44	-	-	HYPH
cord-321013-8pkrg0mx	78	45	sheet	sheet	NN
cord-321013-8pkrg0mx	78	46	and	and	CC
cord-321013-8pkrg0mx	78	47	two	two	CD
cord-321013-8pkrg0mx	78	48	α	α	NN
cord-321013-8pkrg0mx	78	49	-	-	HYPH
cord-321013-8pkrg0mx	78	50	helices	helix	NNS
cord-321013-8pkrg0mx	78	51	[	[	-LRB-
cord-321013-8pkrg0mx	78	52	17	17	CD
cord-321013-8pkrg0mx	78	53	]	]	-RRB-
cord-321013-8pkrg0mx	78	54	.	.	.
cord-321013-8pkrg0mx	79	1	Self	Self	NNP
cord-321013-8pkrg0mx	79	2	-	-	HYPH
cord-321013-8pkrg0mx	79	3	association	association	NNP
cord-321013-8pkrg0mx	79	4	of	of	IN
cord-321013-8pkrg0mx	79	5	the	the	DT
cord-321013-8pkrg0mx	79	6	N	N	NNP
cord-321013-8pkrg0mx	79	7	protein	protein	NN
cord-321013-8pkrg0mx	79	8	has	have	VBZ
cord-321013-8pkrg0mx	79	9	been	be	VBN
cord-321013-8pkrg0mx	79	10	observed	observe	VBN
cord-321013-8pkrg0mx	79	11	in	in	IN
cord-321013-8pkrg0mx	79	12	many	many	JJ
cord-321013-8pkrg0mx	79	13	viruses	virus	NNS
cord-321013-8pkrg0mx	79	14	,	,	,
cord-321013-8pkrg0mx	79	15	and	and	CC
cord-321013-8pkrg0mx	79	16	is	be	VBZ
cord-321013-8pkrg0mx	79	17	required	require	VBN
cord-321013-8pkrg0mx	79	18	for	for	IN
cord-321013-8pkrg0mx	79	19	the	the	DT
cord-321013-8pkrg0mx	79	20	formation	formation	NN
cord-321013-8pkrg0mx	79	21	of	of	IN
cord-321013-8pkrg0mx	79	22	the	the	DT
cord-321013-8pkrg0mx	79	23	viral	viral	JJ
cord-321013-8pkrg0mx	79	24	capsid	capsid	NN
cord-321013-8pkrg0mx	79	25	which	which	WDT
cord-321013-8pkrg0mx	79	26	protects	protect	VBZ
cord-321013-8pkrg0mx	79	27	the	the	DT
cord-321013-8pkrg0mx	79	28	viral	viral	JJ
cord-321013-8pkrg0mx	79	29	genome	genome	NN
cord-321013-8pkrg0mx	79	30	from	from	IN
cord-321013-8pkrg0mx	79	31	extracellular	extracellular	JJ
cord-321013-8pkrg0mx	79	32	agents	agent	NNS
cord-321013-8pkrg0mx	79	33	[	[	-LRB-
cord-321013-8pkrg0mx	79	34	56	56	CD
cord-321013-8pkrg0mx	79	35	]	]	-RRB-
cord-321013-8pkrg0mx	79	36	.	.	.
cord-321013-8pkrg0mx	80	1	In	in	IN
cord-321013-8pkrg0mx	80	2	addition	addition	NN
cord-321013-8pkrg0mx	80	3	to	to	IN
cord-321013-8pkrg0mx	80	4	the	the	DT
cord-321013-8pkrg0mx	80	5	ability	ability	NN
cord-321013-8pkrg0mx	80	6	of	of	IN
cord-321013-8pkrg0mx	80	7	N	n	CD
cord-321013-8pkrg0mx	80	8	protein	protein	NN
cord-321013-8pkrg0mx	80	9	to	to	IN
cord-321013-8pkrg0mx	80	10	oligomerize	oligomerize	NNP
cord-321013-8pkrg0mx	80	11	,	,	,
cord-321013-8pkrg0mx	80	12	viral	viral	JJ
cord-321013-8pkrg0mx	80	13	capsid	capsid	NN
cord-321013-8pkrg0mx	80	14	formation	formation	NN
cord-321013-8pkrg0mx	80	15	also	also	RB
cord-321013-8pkrg0mx	80	16	requires	require	VBZ
cord-321013-8pkrg0mx	80	17	RNA	rna	NN
cord-321013-8pkrg0mx	80	18	-	-	HYPH
cord-321013-8pkrg0mx	80	19	binding	bind	VBG
cord-321013-8pkrg0mx	80	20	ability	ability	NN
cord-321013-8pkrg0mx	80	21	[	[	-LRB-
cord-321013-8pkrg0mx	80	22	58	58	CD
cord-321013-8pkrg0mx	80	23	]	]	-RRB-
cord-321013-8pkrg0mx	80	24	.	.	.
cord-321013-8pkrg0mx	81	1	Studies	study	NNS
cord-321013-8pkrg0mx	81	2	revealed	reveal	VBD
cord-321013-8pkrg0mx	81	3	that	that	IN
cord-321013-8pkrg0mx	81	4	SARS	SARS	NNP
cord-321013-8pkrg0mx	81	5	-	-	HYPH
cord-321013-8pkrg0mx	81	6	CoV	CoV	NNP
cord-321013-8pkrg0mx	81	7	N	n	CD
cord-321013-8pkrg0mx	81	8	protein	protein	NN
cord-321013-8pkrg0mx	81	9	fragments	fragment	NNS
cord-321013-8pkrg0mx	81	10	containing	contain	VBG
cord-321013-8pkrg0mx	81	11	the	the	DT
cord-321013-8pkrg0mx	81	12	dimerization	dimerization	NN
cord-321013-8pkrg0mx	81	13	domain	domain	NN
cord-321013-8pkrg0mx	81	14	(	(	-LRB-
cord-321013-8pkrg0mx	81	15	residues	residue	NNS
cord-321013-8pkrg0mx	81	16	236	236	CD
cord-321013-8pkrg0mx	81	17	-	-	SYM
cord-321013-8pkrg0mx	81	18	384	384	CD
cord-321013-8pkrg0mx	81	19	)	)	-RRB-
cord-321013-8pkrg0mx	81	20	can	can	MD
cord-321013-8pkrg0mx	81	21	bind	bind	VB
cord-321013-8pkrg0mx	81	22	to	to	IN
cord-321013-8pkrg0mx	81	23	a	a	DT
cord-321013-8pkrg0mx	81	24	putative	putative	JJ
cord-321013-8pkrg0mx	81	25	packing	packing	NN
cord-321013-8pkrg0mx	81	26	signal	signal	NN
cord-321013-8pkrg0mx	81	27	within	within	IN
cord-321013-8pkrg0mx	81	28	the	the	DT
cord-321013-8pkrg0mx	81	29	viral	viral	JJ
cord-321013-8pkrg0mx	81	30	RNA	RNA	NNP
cord-321013-8pkrg0mx	81	31	,	,	,
cord-321013-8pkrg0mx	81	32	with	with	IN
cord-321013-8pkrg0mx	81	33	the	the	DT
cord-321013-8pkrg0mx	81	34	most	most	RBS
cord-321013-8pkrg0mx	81	35	likely	likely	JJ
cord-321013-8pkrg0mx	81	36	RNA	RNA	NNP
cord-321013-8pkrg0mx	81	37	binding	binding	NN
cord-321013-8pkrg0mx	81	38	site	site	NN
cord-321013-8pkrg0mx	81	39	being	be	VBG
cord-321013-8pkrg0mx	81	40	within	within	IN
cord-321013-8pkrg0mx	81	41	the	the	DT
cord-321013-8pkrg0mx	81	42	basic	basic	JJ
cord-321013-8pkrg0mx	81	43	region	region	NN
cord-321013-8pkrg0mx	81	44	between	between	IN
cord-321013-8pkrg0mx	81	45	residues	residue	NNS
cord-321013-8pkrg0mx	81	46	248	248	CD
cord-321013-8pkrg0mx	81	47	-	-	HYPH
cord-321013-8pkrg0mx	81	48	280	280	CD
cord-321013-8pkrg0mx	81	49	[	[	-LRB-
cord-321013-8pkrg0mx	81	50	59	59	CD
cord-321013-8pkrg0mx	81	51	]	]	-RRB-
cord-321013-8pkrg0mx	81	52	.	.	.
cord-321013-8pkrg0mx	82	1	NMR	NMR	NNP
cord-321013-8pkrg0mx	82	2	studies	study	NNS
cord-321013-8pkrg0mx	82	3	then	then	RB
cord-321013-8pkrg0mx	82	4	showed	show	VBD
cord-321013-8pkrg0mx	82	5	that	that	IN
cord-321013-8pkrg0mx	82	6	the	the	DT
cord-321013-8pkrg0mx	82	7	RNA	RNA	NNP
cord-321013-8pkrg0mx	82	8	-	-	HYPH
cord-321013-8pkrg0mx	82	9	binding	bind	VBG
cord-321013-8pkrg0mx	82	10	site	site	NN
cord-321013-8pkrg0mx	82	11	between	between	IN
cord-321013-8pkrg0mx	82	12	residues	residue	NNS
cord-321013-8pkrg0mx	82	13	248	248	CD
cord-321013-8pkrg0mx	82	14	-	-	HYPH
cord-321013-8pkrg0mx	82	15	280	280	CD
cord-321013-8pkrg0mx	82	16	formed	form	VBN
cord-321013-8pkrg0mx	82	17	part	part	NN
cord-321013-8pkrg0mx	82	18	of	of	IN
cord-321013-8pkrg0mx	82	19	the	the	DT
cord-321013-8pkrg0mx	82	20	complete	complete	JJ
cord-321013-8pkrg0mx	82	21	dimerization	dimerization	NN
cord-321013-8pkrg0mx	82	22	domain	domain	NN
cord-321013-8pkrg0mx	82	23	structure	structure	NN
cord-321013-8pkrg0mx	82	24	[	[	-LRB-
cord-321013-8pkrg0mx	82	25	17	17	CD
cord-321013-8pkrg0mx	82	26	]	]	-RRB-
cord-321013-8pkrg0mx	82	27	.	.	.
cord-321013-8pkrg0mx	83	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	83	2	was	be	VBD
cord-321013-8pkrg0mx	83	3	not	not	RB
cord-321013-8pkrg0mx	83	4	until	until	IN
cord-321013-8pkrg0mx	83	5	the	the	DT
cord-321013-8pkrg0mx	83	6	crystal	crystal	NN
cord-321013-8pkrg0mx	83	7	structure	structure	NN
cord-321013-8pkrg0mx	83	8	of	of	IN
cord-321013-8pkrg0mx	83	9	SARS	SARS	NNP
cord-321013-8pkrg0mx	83	10	N	N	NNP
cord-321013-8pkrg0mx	83	11	CTD	CTD	NNP
cord-321013-8pkrg0mx	83	12	was	be	VBD
cord-321013-8pkrg0mx	83	13	resolved	resolve	VBN
cord-321013-8pkrg0mx	83	14	that	that	IN
cord-321013-8pkrg0mx	83	15	the	the	DT
cord-321013-8pkrg0mx	83	16	molecular	molecular	JJ
cord-321013-8pkrg0mx	83	17	basis	basis	NN
cord-321013-8pkrg0mx	83	18	of	of	IN
cord-321013-8pkrg0mx	83	19	RNA	rna	NN
cord-321013-8pkrg0mx	83	20	-	-	HYPH
cord-321013-8pkrg0mx	83	21	binding	bind	VBG
cord-321013-8pkrg0mx	83	22	activity	activity	NN
cord-321013-8pkrg0mx	83	23	and	and	CC
cord-321013-8pkrg0mx	83	24	organization	organization	NN
cord-321013-8pkrg0mx	83	25	of	of	IN
cord-321013-8pkrg0mx	83	26	the	the	DT
cord-321013-8pkrg0mx	83	27	CTD	CTD	NNP
cord-321013-8pkrg0mx	83	28	octamer	octamer	NNP
cord-321013-8pkrg0mx	83	29	was	be	VBD
cord-321013-8pkrg0mx	83	30	determined	determine	VBN
cord-321013-8pkrg0mx	83	31	.	.	.
cord-321013-8pkrg0mx	84	1	The	the	DT
cord-321013-8pkrg0mx	84	2	CTD	CTD	NNP
cord-321013-8pkrg0mx	84	3	spanning	span	VBG
cord-321013-8pkrg0mx	84	4	residues	residue	NNS
cord-321013-8pkrg0mx	84	5	248	248	CD
cord-321013-8pkrg0mx	84	6	-	-	HYPH
cord-321013-8pkrg0mx	84	7	365	365	CD
cord-321013-8pkrg0mx	84	8	(	(	-LRB-
cord-321013-8pkrg0mx	84	9	NP248	NP248	NNP
cord-321013-8pkrg0mx	84	10	-	-	HYPH
cord-321013-8pkrg0mx	84	11	365	365	CD
cord-321013-8pkrg0mx	84	12	)	)	-RRB-
cord-321013-8pkrg0mx	84	13	revealed	reveal	VBD
cord-321013-8pkrg0mx	84	14	that	that	IN
cord-321013-8pkrg0mx	84	15	,	,	,
cord-321013-8pkrg0mx	84	16	due	due	IN
cord-321013-8pkrg0mx	84	17	to	to	IN
cord-321013-8pkrg0mx	84	18	the	the	DT
cord-321013-8pkrg0mx	84	19	presence	presence	NN
cord-321013-8pkrg0mx	84	20	of	of	IN
cord-321013-8pkrg0mx	84	21	the	the	DT
cord-321013-8pkrg0mx	84	22	eight	eight	CD
cord-321013-8pkrg0mx	84	23	positively	positively	RB
cord-321013-8pkrg0mx	84	24	charged	charge	VBN
cord-321013-8pkrg0mx	84	25	lysine	lysine	NN
cord-321013-8pkrg0mx	84	26	and	and	CC
cord-321013-8pkrg0mx	84	27	arginine	arginine	NN
cord-321013-8pkrg0mx	84	28	residues	residue	NNS
cord-321013-8pkrg0mx	84	29	,	,	,
cord-321013-8pkrg0mx	84	30	amino	amino	JJ
cord-321013-8pkrg0mx	84	31	acids	acid	NNS
cord-321013-8pkrg0mx	84	32	248	248	CD
cord-321013-8pkrg0mx	84	33	-	-	HYPH
cord-321013-8pkrg0mx	84	34	280	280	CD
cord-321013-8pkrg0mx	84	35	form	form	NN
cord-321013-8pkrg0mx	84	36	a	a	DT
cord-321013-8pkrg0mx	84	37	positively	positively	RB
cord-321013-8pkrg0mx	84	38	charged	charge	VBN
cord-321013-8pkrg0mx	84	39	groove	groove	NN
cord-321013-8pkrg0mx	84	40	,	,	,
cord-321013-8pkrg0mx	84	41	one	one	CD
cord-321013-8pkrg0mx	84	42	of	of	IN
cord-321013-8pkrg0mx	84	43	the	the	DT
cord-321013-8pkrg0mx	84	44	most	most	RBS
cord-321013-8pkrg0mx	84	45	positively	positively	RB
cord-321013-8pkrg0mx	84	46	charged	charge	VBN
cord-321013-8pkrg0mx	84	47	regions	region	NNS
cord-321013-8pkrg0mx	84	48	of	of	IN
cord-321013-8pkrg0mx	84	49	the	the	DT
cord-321013-8pkrg0mx	84	50	N	N	NNP
cord-321013-8pkrg0mx	84	51	protein	protein	NN
cord-321013-8pkrg0mx	84	52	[	[	-LRB-
cord-321013-8pkrg0mx	84	53	55	55	CD
cord-321013-8pkrg0mx	84	54	]	]	-RRB-
cord-321013-8pkrg0mx	84	55	.	.	.
cord-321013-8pkrg0mx	85	1	This	this	DT
cord-321013-8pkrg0mx	85	2	groove	groove	NN
cord-321013-8pkrg0mx	85	3	is	be	VBZ
cord-321013-8pkrg0mx	85	4	similar	similar	JJ
cord-321013-8pkrg0mx	85	5	to	to	IN
cord-321013-8pkrg0mx	85	6	that	that	DT
cord-321013-8pkrg0mx	85	7	in	in	IN
cord-321013-8pkrg0mx	85	8	IBV	IBV	NNP
cord-321013-8pkrg0mx	85	9	-	-	HYPH
cord-321013-8pkrg0mx	85	10	N	N	NNP
cord-321013-8pkrg0mx	85	11	CTD	CTD	NNP
cord-321013-8pkrg0mx	85	12	,	,	,
cord-321013-8pkrg0mx	85	13	except	except	IN
cord-321013-8pkrg0mx	85	14	that	that	IN
cord-321013-8pkrg0mx	85	15	the	the	DT
cord-321013-8pkrg0mx	85	16	positively	positively	RB
cord-321013-8pkrg0mx	85	17	charged	charge	VBN
cord-321013-8pkrg0mx	85	18	surface	surface	NN
cord-321013-8pkrg0mx	85	19	area	area	NN
cord-321013-8pkrg0mx	85	20	is	be	VBZ
cord-321013-8pkrg0mx	85	21	larger	large	JJR
cord-321013-8pkrg0mx	85	22	in	in	IN
cord-321013-8pkrg0mx	85	23	the	the	DT
cord-321013-8pkrg0mx	85	24	SARS	SARS	NNP
cord-321013-8pkrg0mx	85	25	-	-	HYPH
cord-321013-8pkrg0mx	85	26	CoV	CoV	NNP
cord-321013-8pkrg0mx	85	27	construct	construct	NN
cord-321013-8pkrg0mx	85	28	than	than	IN
cord-321013-8pkrg0mx	85	29	in	in	IN
cord-321013-8pkrg0mx	85	30	the	the	DT
cord-321013-8pkrg0mx	85	31	IBV	IBV	NNP
cord-321013-8pkrg0mx	85	32	[	[	-LRB-
cord-321013-8pkrg0mx	85	33	20	20	CD
cord-321013-8pkrg0mx	85	34	]	]	-RRB-
cord-321013-8pkrg0mx	85	35	,	,	,
cord-321013-8pkrg0mx	85	36	due	due	JJ
cord-321013-8pkrg0mx	85	37	in	in	IN
cord-321013-8pkrg0mx	85	38	part	part	NN
cord-321013-8pkrg0mx	85	39	to	to	IN
cord-321013-8pkrg0mx	85	40	the	the	DT
cord-321013-8pkrg0mx	85	41	presence	presence	NN
cord-321013-8pkrg0mx	85	42	of	of	IN
cord-321013-8pkrg0mx	85	43	additional	additional	JJ
cord-321013-8pkrg0mx	85	44	negatively	negatively	RB
cord-321013-8pkrg0mx	85	45	charged	charge	VBN
cord-321013-8pkrg0mx	85	46	residues	residue	NNS
cord-321013-8pkrg0mx	85	47	in	in	IN
cord-321013-8pkrg0mx	85	48	the	the	DT
cord-321013-8pkrg0mx	85	49	IBV	IBV	NNP
cord-321013-8pkrg0mx	85	50	N	N	NNP
cord-321013-8pkrg0mx	85	51	protein	protein	NN
cord-321013-8pkrg0mx	85	52	and	and	CC
cord-321013-8pkrg0mx	85	53	in	in	IN
cord-321013-8pkrg0mx	85	54	part	part	NN
cord-321013-8pkrg0mx	85	55	due	due	IN
cord-321013-8pkrg0mx	85	56	to	to	IN
cord-321013-8pkrg0mx	85	57	the	the	DT
cord-321013-8pkrg0mx	85	58	absence	absence	NN
cord-321013-8pkrg0mx	85	59	of	of	IN
cord-321013-8pkrg0mx	85	60	residues	residue	NNS
cord-321013-8pkrg0mx	85	61	215	215	CD
cord-321013-8pkrg0mx	85	62	-	-	SYM
cord-321013-8pkrg0mx	85	63	218	218	CD
cord-321013-8pkrg0mx	85	64	from	from	IN
cord-321013-8pkrg0mx	85	65	the	the	DT
cord-321013-8pkrg0mx	85	66	IBV	IBV	NNP
cord-321013-8pkrg0mx	85	67	construct	construct	NN
cord-321013-8pkrg0mx	85	68	,	,	,
cord-321013-8pkrg0mx	85	69	which	which	WDT
cord-321013-8pkrg0mx	85	70	contain	contain	VBP
cord-321013-8pkrg0mx	85	71	two	two	CD
cord-321013-8pkrg0mx	85	72	lysine	lysine	NN
cord-321013-8pkrg0mx	85	73	residue	residue	NN
cord-321013-8pkrg0mx	85	74	in	in	IN
cord-321013-8pkrg0mx	85	75	the	the	DT
cord-321013-8pkrg0mx	85	76	SARS	SARS	NNP
cord-321013-8pkrg0mx	85	77	-	-	HYPH
cord-321013-8pkrg0mx	85	78	CoV	CoV	NNP
cord-321013-8pkrg0mx	85	79	construct	construct	VBP
cord-321013-8pkrg0mx	85	80	[	[	-LRB-
cord-321013-8pkrg0mx	85	81	55	55	CD
cord-321013-8pkrg0mx	85	82	]	]	-RRB-
cord-321013-8pkrg0mx	85	83	.	.	.
cord-321013-8pkrg0mx	86	1	The	the	DT
cord-321013-8pkrg0mx	86	2	NP248	NP248	NNP
cord-321013-8pkrg0mx	86	3	-	-	HYPH
cord-321013-8pkrg0mx	86	4	365	365	CD
cord-321013-8pkrg0mx	86	5	construct	construct	NN
cord-321013-8pkrg0mx	86	6	,	,	,
cord-321013-8pkrg0mx	86	7	which	which	WDT
cord-321013-8pkrg0mx	86	8	contains	contain	VBZ
cord-321013-8pkrg0mx	86	9	both	both	CC
cord-321013-8pkrg0mx	86	10	the	the	DT
cord-321013-8pkrg0mx	86	11	charge	charge	NN
cord-321013-8pkrg0mx	86	12	-	-	HYPH
cord-321013-8pkrg0mx	86	13	rich	rich	JJ
cord-321013-8pkrg0mx	86	14	region	region	NN
cord-321013-8pkrg0mx	86	15	(	(	-LRB-
cord-321013-8pkrg0mx	86	16	residues	residue	NNS
cord-321013-8pkrg0mx	86	17	248	248	CD
cord-321013-8pkrg0mx	86	18	-	-	HYPH
cord-321013-8pkrg0mx	86	19	280	280	CD
cord-321013-8pkrg0mx	86	20	)	)	-RRB-
cord-321013-8pkrg0mx	86	21	and	and	CC
cord-321013-8pkrg0mx	86	22	dimerization	dimerization	NN
cord-321013-8pkrg0mx	86	23	core	core	NN
cord-321013-8pkrg0mx	86	24	(	(	-LRB-
cord-321013-8pkrg0mx	86	25	residues	residue	NNS
cord-321013-8pkrg0mx	86	26	281	281	CD
cord-321013-8pkrg0mx	86	27	-	-	HYPH
cord-321013-8pkrg0mx	86	28	365	365	CD
cord-321013-8pkrg0mx	86	29	)	)	-RRB-
cord-321013-8pkrg0mx	86	30	of	of	IN
cord-321013-8pkrg0mx	86	31	the	the	DT
cord-321013-8pkrg0mx	86	32	dimerization	dimerization	NN
cord-321013-8pkrg0mx	86	33	domain	domain	NN
cord-321013-8pkrg0mx	86	34	,	,	,
cord-321013-8pkrg0mx	86	35	is	be	VBZ
cord-321013-8pkrg0mx	86	36	capable	capable	JJ
cord-321013-8pkrg0mx	86	37	of	of	IN
cord-321013-8pkrg0mx	86	38	binding	bind	VBG
cord-321013-8pkrg0mx	86	39	to	to	IN
cord-321013-8pkrg0mx	86	40	single	single	RB
cord-321013-8pkrg0mx	86	41	-	-	HYPH
cord-321013-8pkrg0mx	86	42	stranded	strand	VBN
cord-321013-8pkrg0mx	86	43	RNA	RNA	NNP
cord-321013-8pkrg0mx	86	44	(	(	-LRB-
cord-321013-8pkrg0mx	86	45	ssRNA	ssRNA	VBG
cord-321013-8pkrg0mx	86	46	)	)	-RRB-
cord-321013-8pkrg0mx	86	47	,	,	,
cord-321013-8pkrg0mx	86	48	single	single	RB
cord-321013-8pkrg0mx	86	49	-	-	HYPH
cord-321013-8pkrg0mx	86	50	stranded	strand	VBN
cord-321013-8pkrg0mx	86	51	DNA	dna	NN
cord-321013-8pkrg0mx	86	52	(	(	-LRB-
cord-321013-8pkrg0mx	86	53	ssDNA	ssdna	NN
cord-321013-8pkrg0mx	86	54	)	)	-RRB-
cord-321013-8pkrg0mx	86	55	and	and	CC
cord-321013-8pkrg0mx	86	56	double	double	RB
cord-321013-8pkrg0mx	86	57	-	-	HYPH
cord-321013-8pkrg0mx	86	58	stranded	strand	VBN
cord-321013-8pkrg0mx	86	59	DNA	dna	NN
cord-321013-8pkrg0mx	86	60	(	(	-LRB-
cord-321013-8pkrg0mx	86	61	dsDNA	dsdna	RB
cord-321013-8pkrg0mx	86	62	)	)	-RRB-
cord-321013-8pkrg0mx	86	63	,	,	,
cord-321013-8pkrg0mx	86	64	and	and	CC
cord-321013-8pkrg0mx	86	65	NP248	NP248	NNP
cord-321013-8pkrg0mx	86	66	-	-	HYPH
cord-321013-8pkrg0mx	86	67	365	365	CD
cord-321013-8pkrg0mx	86	68	has	have	VBZ
cord-321013-8pkrg0mx	86	69	stronger	strong	JJR
cord-321013-8pkrg0mx	86	70	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	86	71	acid	acid	NN
cord-321013-8pkrg0mx	86	72	-	-	HYPH
cord-321013-8pkrg0mx	86	73	binding	bind	VBG
cord-321013-8pkrg0mx	86	74	activity	activity	NN
cord-321013-8pkrg0mx	86	75	than	than	IN
cord-321013-8pkrg0mx	86	76	the	the	DT
cord-321013-8pkrg0mx	86	77	NTD	NTD	NNP
cord-321013-8pkrg0mx	86	78	[	[	-LRB-
cord-321013-8pkrg0mx	86	79	55	55	CD
cord-321013-8pkrg0mx	86	80	,	,	,
cord-321013-8pkrg0mx	86	81	57	57	CD
cord-321013-8pkrg0mx	86	82	]	]	-RRB-
cord-321013-8pkrg0mx	86	83	.	.	.
cord-321013-8pkrg0mx	87	1	The	the	DT
cord-321013-8pkrg0mx	87	2	strong	strong	JJ
cord-321013-8pkrg0mx	87	3	electrostatic	electrostatic	JJ
cord-321013-8pkrg0mx	87	4	character	character	NN
cord-321013-8pkrg0mx	87	5	of	of	IN
cord-321013-8pkrg0mx	87	6	residues	residue	NNS
cord-321013-8pkrg0mx	87	7	248	248	CD
cord-321013-8pkrg0mx	87	8	-	-	HYPH
cord-321013-8pkrg0mx	87	9	280	280	CD
cord-321013-8pkrg0mx	87	10	and	and	CC
cord-321013-8pkrg0mx	87	11	the	the	DT
cord-321013-8pkrg0mx	87	12	fact	fact	NN
cord-321013-8pkrg0mx	87	13	that	that	IN
cord-321013-8pkrg0mx	87	14	both	both	DT
cord-321013-8pkrg0mx	87	15	ssRNA	ssrna	UH
cord-321013-8pkrg0mx	87	16	,	,	,
cord-321013-8pkrg0mx	87	17	ssDNA	ssdna	JJ
cord-321013-8pkrg0mx	87	18	and	and	CC
cord-321013-8pkrg0mx	87	19	ddDNA	dddna	RB
cord-321013-8pkrg0mx	87	20	bind	bind	VB
cord-321013-8pkrg0mx	87	21	to	to	IN
cord-321013-8pkrg0mx	87	22	NP248	NP248	NNP
cord-321013-8pkrg0mx	87	23	-	-	HYPH
cord-321013-8pkrg0mx	87	24	365	365	CD
cord-321013-8pkrg0mx	87	25	,	,	,
cord-321013-8pkrg0mx	87	26	strongly	strongly	RB
cord-321013-8pkrg0mx	87	27	indicates	indicate	VBZ
cord-321013-8pkrg0mx	87	28	that	that	IN
cord-321013-8pkrg0mx	87	29	oligonucleotide	oligonucleotide	JJ
cord-321013-8pkrg0mx	87	30	binding	binding	NN
cord-321013-8pkrg0mx	87	31	is	be	VBZ
cord-321013-8pkrg0mx	87	32	based	base	VBN
cord-321013-8pkrg0mx	87	33	on	on	IN
cord-321013-8pkrg0mx	87	34	non	non	JJ
cord-321013-8pkrg0mx	87	35	-	-	JJ
cord-321013-8pkrg0mx	87	36	specific	specific	JJ
cord-321013-8pkrg0mx	87	37	charge	charge	NN
cord-321013-8pkrg0mx	87	38	interactions	interaction	NNS
cord-321013-8pkrg0mx	87	39	between	between	IN
cord-321013-8pkrg0mx	87	40	the	the	DT
cord-321013-8pkrg0mx	87	41	positively	positively	RB
cord-321013-8pkrg0mx	87	42	charged	charge	VBN
cord-321013-8pkrg0mx	87	43	protein	protein	NN
cord-321013-8pkrg0mx	87	44	and	and	CC
cord-321013-8pkrg0mx	87	45	the	the	DT
cord-321013-8pkrg0mx	87	46	negatively	negatively	RB
cord-321013-8pkrg0mx	87	47	charged	charge	VBN
cord-321013-8pkrg0mx	87	48	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	87	49	acid	acid	NN
cord-321013-8pkrg0mx	87	50	backbone	backbone	NN
cord-321013-8pkrg0mx	87	51	[	[	-LRB-
cord-321013-8pkrg0mx	87	52	55	55	CD
cord-321013-8pkrg0mx	87	53	,	,	,
cord-321013-8pkrg0mx	87	54	60	60	CD
cord-321013-8pkrg0mx	87	55	]	]	-RRB-
cord-321013-8pkrg0mx	87	56	.	.	.
cord-321013-8pkrg0mx	88	1	By	by	IN
cord-321013-8pkrg0mx	88	2	keeping	keep	VBG
cord-321013-8pkrg0mx	88	3	the	the	DT
cord-321013-8pkrg0mx	88	4	RNA	RNA	NNP
cord-321013-8pkrg0mx	88	5	-	-	HYPH
cord-321013-8pkrg0mx	88	6	binding	bind	VBG
cord-321013-8pkrg0mx	88	7	domains	domain	NNS
cord-321013-8pkrg0mx	88	8	in	in	IN
cord-321013-8pkrg0mx	88	9	close	close	JJ
cord-321013-8pkrg0mx	88	10	proximity	proximity	NN
cord-321013-8pkrg0mx	88	11	to	to	IN
cord-321013-8pkrg0mx	88	12	the	the	DT
cord-321013-8pkrg0mx	88	13	CTD	CTD	NNP
cord-321013-8pkrg0mx	88	14	,	,	,
cord-321013-8pkrg0mx	88	15	the	the	DT
cord-321013-8pkrg0mx	88	16	formation	formation	NN
cord-321013-8pkrg0mx	88	17	of	of	IN
cord-321013-8pkrg0mx	88	18	a	a	DT
cord-321013-8pkrg0mx	88	19	large	large	JJ
cord-321013-8pkrg0mx	88	20	helical	helical	JJ
cord-321013-8pkrg0mx	88	21	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	88	22	core	core	NN
cord-321013-8pkrg0mx	88	23	is	be	VBZ
cord-321013-8pkrg0mx	88	24	therefore	therefore	RB
cord-321013-8pkrg0mx	88	25	possible	possible	JJ
cord-321013-8pkrg0mx	88	26	[	[	-LRB-
cord-321013-8pkrg0mx	88	27	47	47	CD
cord-321013-8pkrg0mx	88	28	]	]	-RRB-
cord-321013-8pkrg0mx	88	29	.	.	.
cord-321013-8pkrg0mx	89	1	Association	Association	NNP
cord-321013-8pkrg0mx	89	2	of	of	IN
cord-321013-8pkrg0mx	89	3	the	the	DT
cord-321013-8pkrg0mx	89	4	N	N	NNP
cord-321013-8pkrg0mx	89	5	protein	protein	NN
cord-321013-8pkrg0mx	89	6	dimers	dimer	NNS
cord-321013-8pkrg0mx	89	7	is	be	VBZ
cord-321013-8pkrg0mx	89	8	necessary	necessary	JJ
cord-321013-8pkrg0mx	89	9	for	for	IN
cord-321013-8pkrg0mx	89	10	further	further	JJ
cord-321013-8pkrg0mx	89	11	assembly	assembly	NN
cord-321013-8pkrg0mx	89	12	of	of	IN
cord-321013-8pkrg0mx	89	13	the	the	DT
cord-321013-8pkrg0mx	89	14	core	core	NN
cord-321013-8pkrg0mx	89	15	.	.	.
cord-321013-8pkrg0mx	90	1	The	the	DT
cord-321013-8pkrg0mx	90	2	full	full	JJ
cord-321013-8pkrg0mx	90	3	-	-	HYPH
cord-321013-8pkrg0mx	90	4	length	length	NN
cord-321013-8pkrg0mx	90	5	dimeric	dimeric	JJ
cord-321013-8pkrg0mx	90	6	N	n	CD
cord-321013-8pkrg0mx	90	7	protein	protein	NN
cord-321013-8pkrg0mx	90	8	has	have	VBZ
cord-321013-8pkrg0mx	90	9	a	a	DT
cord-321013-8pkrg0mx	90	10	tendancy	tendancy	NN
cord-321013-8pkrg0mx	90	11	to	to	TO
cord-321013-8pkrg0mx	90	12	form	form	VB
cord-321013-8pkrg0mx	90	13	tetramers	tetramer	NNS
cord-321013-8pkrg0mx	90	14	and	and	CC
cord-321013-8pkrg0mx	90	15	higher	high	JJR
cord-321013-8pkrg0mx	90	16	molecular	molecular	JJ
cord-321013-8pkrg0mx	90	17	weight	weight	NN
cord-321013-8pkrg0mx	90	18	oligomers	oligomer	NNS
cord-321013-8pkrg0mx	90	19	in	in	IN
cord-321013-8pkrg0mx	90	20	vitro	vitro	FW
cord-321013-8pkrg0mx	90	21	[	[	-LRB-
cord-321013-8pkrg0mx	90	22	54	54	CD
cord-321013-8pkrg0mx	90	23	]	]	-RRB-
cord-321013-8pkrg0mx	90	24	,	,	,
cord-321013-8pkrg0mx	90	25	and	and	CC
cord-321013-8pkrg0mx	90	26	a	a	DT
cord-321013-8pkrg0mx	90	27	serine	serine	NN
cord-321013-8pkrg0mx	90	28	/	/	SYM
cord-321013-8pkrg0mx	90	29	arginine	arginine	NN
cord-321013-8pkrg0mx	90	30	-	-	HYPH
cord-321013-8pkrg0mx	90	31	rich	rich	JJ
cord-321013-8pkrg0mx	90	32	motif	motif	NN
cord-321013-8pkrg0mx	90	33	(	(	-LRB-
cord-321013-8pkrg0mx	90	34	residues	residue	NNS
cord-321013-8pkrg0mx	90	35	184	184	CD
cord-321013-8pkrg0mx	90	36	-	-	SYM
cord-321013-8pkrg0mx	90	37	196	196	CD
cord-321013-8pkrg0mx	90	38	)	)	-RRB-
cord-321013-8pkrg0mx	90	39	has	have	VBZ
cord-321013-8pkrg0mx	90	40	been	be	VBN
cord-321013-8pkrg0mx	90	41	shown	show	VBN
cord-321013-8pkrg0mx	90	42	to	to	TO
cord-321013-8pkrg0mx	90	43	be	be	VB
cord-321013-8pkrg0mx	90	44	important	important	JJ
cord-321013-8pkrg0mx	90	45	for	for	IN
cord-321013-8pkrg0mx	90	46	N	n	CD
cord-321013-8pkrg0mx	90	47	protein	protein	NN
cord-321013-8pkrg0mx	90	48	oligomerization	oligomerization	NN
cord-321013-8pkrg0mx	90	49	[	[	-LRB-
cord-321013-8pkrg0mx	90	50	44	44	CD
cord-321013-8pkrg0mx	90	51	]	]	-RRB-
cord-321013-8pkrg0mx	90	52	.	.	.
cord-321013-8pkrg0mx	91	1	Two	two	CD
cord-321013-8pkrg0mx	91	2	dimers	dimer	NNS
cord-321013-8pkrg0mx	91	3	arrange	arrange	VBP
cord-321013-8pkrg0mx	91	4	themselves	-PRON-	PRP
cord-321013-8pkrg0mx	91	5	into	into	IN
cord-321013-8pkrg0mx	91	6	a	a	DT
cord-321013-8pkrg0mx	91	7	butterfly	butterfly	NN
cord-321013-8pkrg0mx	91	8	-	-	HYPH
cord-321013-8pkrg0mx	91	9	shaped	shape	VBN
cord-321013-8pkrg0mx	91	10	tetramer	tetramer	NN
cord-321013-8pkrg0mx	91	11	,	,	,
cord-321013-8pkrg0mx	91	12	while	while	IN
cord-321013-8pkrg0mx	91	13	two	two	CD
cord-321013-8pkrg0mx	91	14	butterfly	butterfly	NN
cord-321013-8pkrg0mx	91	15	-	-	HYPH
cord-321013-8pkrg0mx	91	16	shaped	shape	VBN
cord-321013-8pkrg0mx	91	17	tetramers	tetramer	NNS
cord-321013-8pkrg0mx	91	18	unite	unite	VBP
cord-321013-8pkrg0mx	91	19	to	to	TO
cord-321013-8pkrg0mx	91	20	form	form	VB
cord-321013-8pkrg0mx	91	21	an	an	DT
cord-321013-8pkrg0mx	91	22	octamer	octamer	NN
cord-321013-8pkrg0mx	91	23	in	in	IN
cord-321013-8pkrg0mx	91	24	the	the	DT
cord-321013-8pkrg0mx	91	25	asymmetric	asymmetric	JJ
cord-321013-8pkrg0mx	91	26	unit	unit	NN
cord-321013-8pkrg0mx	91	27	of	of	IN
cord-321013-8pkrg0mx	91	28	the	the	DT
cord-321013-8pkrg0mx	91	29	CTD	CTD	NNP
cord-321013-8pkrg0mx	91	30	crystal	crystal	NN
cord-321013-8pkrg0mx	91	31	[	[	-LRB-
cord-321013-8pkrg0mx	91	32	55	55	CD
cord-321013-8pkrg0mx	91	33	]	]	-RRB-
cord-321013-8pkrg0mx	91	34	.	.	.
cord-321013-8pkrg0mx	92	1	The	the	DT
cord-321013-8pkrg0mx	92	2	octamer	octamer	NN
cord-321013-8pkrg0mx	92	3	is	be	VBZ
cord-321013-8pkrg0mx	92	4	held	hold	VBN
cord-321013-8pkrg0mx	92	5	together	together	RB
cord-321013-8pkrg0mx	92	6	through	through	IN
cord-321013-8pkrg0mx	92	7	hydrophobic	hydrophobic	JJ
cord-321013-8pkrg0mx	92	8	interactions	interaction	NNS
cord-321013-8pkrg0mx	92	9	and	and	CC
cord-321013-8pkrg0mx	92	10	hydrophilic	hydrophilic	JJ
cord-321013-8pkrg0mx	92	11	contacts	contact	NNS
cord-321013-8pkrg0mx	92	12	among	among	IN
cord-321013-8pkrg0mx	92	13	the	the	DT
cord-321013-8pkrg0mx	92	14	four	four	CD
cord-321013-8pkrg0mx	92	15	dimers	dimer	NNS
cord-321013-8pkrg0mx	92	16	,	,	,
cord-321013-8pkrg0mx	92	17	and	and	CC
cord-321013-8pkrg0mx	92	18	networks	network	NNS
cord-321013-8pkrg0mx	92	19	of	of	IN
cord-321013-8pkrg0mx	92	20	inter	inter	JJ
cord-321013-8pkrg0mx	92	21	-	-	JJ
cord-321013-8pkrg0mx	92	22	dimer	dimer	JJ
cord-321013-8pkrg0mx	92	23	hydrogen	hydrogen	NN
cord-321013-8pkrg0mx	92	24	bonds	bond	NNS
cord-321013-8pkrg0mx	92	25	further	further	RB
cord-321013-8pkrg0mx	92	26	help	help	VBP
cord-321013-8pkrg0mx	92	27	stabilize	stabilize	VB
cord-321013-8pkrg0mx	92	28	the	the	DT
cord-321013-8pkrg0mx	92	29	octamer	octamer	NN
cord-321013-8pkrg0mx	92	30	[	[	-LRB-
cord-321013-8pkrg0mx	92	31	55	55	CD
cord-321013-8pkrg0mx	92	32	]	]	-RRB-
cord-321013-8pkrg0mx	92	33	.	.	.
cord-321013-8pkrg0mx	93	1	Crystallography	crystallography	NN
cord-321013-8pkrg0mx	93	2	studies	study	NNS
cord-321013-8pkrg0mx	93	3	have	have	VBP
cord-321013-8pkrg0mx	93	4	demonstrated	demonstrate	VBN
cord-321013-8pkrg0mx	93	5	that	that	IN
cord-321013-8pkrg0mx	93	6	CoV	cov	NN
cord-321013-8pkrg0mx	93	7	-	-	HYPH
cord-321013-8pkrg0mx	93	8	SARS	SARS	NNP
cord-321013-8pkrg0mx	93	9	CTD	CTD	NNP
cord-321013-8pkrg0mx	93	10	(	(	-LRB-
cord-321013-8pkrg0mx	93	11	NP248	NP248	NNP
cord-321013-8pkrg0mx	93	12	-	-	HYPH
cord-321013-8pkrg0mx	93	13	365	365	CD
cord-321013-8pkrg0mx	93	14	)	)	-RRB-
cord-321013-8pkrg0mx	93	15	packs	pack	NNS
cord-321013-8pkrg0mx	93	16	as	as	IN
cord-321013-8pkrg0mx	93	17	an	an	DT
cord-321013-8pkrg0mx	93	18	octamer	octamer	NN
cord-321013-8pkrg0mx	93	19	which	which	WDT
cord-321013-8pkrg0mx	93	20	stacks	stack	VBZ
cord-321013-8pkrg0mx	93	21	to	to	TO
cord-321013-8pkrg0mx	93	22	form	form	VB
cord-321013-8pkrg0mx	93	23	a	a	DT
cord-321013-8pkrg0mx	93	24	helical	helical	JJ
cord-321013-8pkrg0mx	93	25	supercomplex	supercomplex	NN
cord-321013-8pkrg0mx	93	26	structure	structure	NN
cord-321013-8pkrg0mx	93	27	with	with	IN
cord-321013-8pkrg0mx	93	28	a	a	DT
cord-321013-8pkrg0mx	93	29	continuous	continuous	JJ
cord-321013-8pkrg0mx	93	30	positively	positively	RB
cord-321013-8pkrg0mx	93	31	charged	charge	VBN
cord-321013-8pkrg0mx	93	32	surface	surface	NN
cord-321013-8pkrg0mx	93	33	that	that	WDT
cord-321013-8pkrg0mx	93	34	could	could	MD
cord-321013-8pkrg0mx	93	35	potentially	potentially	RB
cord-321013-8pkrg0mx	93	36	allow	allow	VB
cord-321013-8pkrg0mx	93	37	viral	viral	JJ
cord-321013-8pkrg0mx	93	38	RNA	RNA	NNP
cord-321013-8pkrg0mx	93	39	strands	strand	NNS
cord-321013-8pkrg0mx	93	40	to	to	TO
cord-321013-8pkrg0mx	93	41	bind	bind	VB
cord-321013-8pkrg0mx	93	42	and	and	CC
cord-321013-8pkrg0mx	93	43	wrap	wrap	VB
cord-321013-8pkrg0mx	93	44	around	around	RP
cord-321013-8pkrg0mx	93	45	the	the	DT
cord-321013-8pkrg0mx	93	46	helical	helical	JJ
cord-321013-8pkrg0mx	93	47	oligomer	oligomer	NNP
cord-321013-8pkrg0mx	93	48	structure	structure	NN
cord-321013-8pkrg0mx	93	49	through	through	IN
cord-321013-8pkrg0mx	93	50	electrostatic	electrostatic	JJ
cord-321013-8pkrg0mx	93	51	interactions	interaction	NNS
cord-321013-8pkrg0mx	93	52	[	[	-LRB-
cord-321013-8pkrg0mx	93	53	55	55	CD
cord-321013-8pkrg0mx	93	54	]	]	-RRB-
cord-321013-8pkrg0mx	93	55	.	.	.
cord-321013-8pkrg0mx	94	1	The	the	DT
cord-321013-8pkrg0mx	94	2	existence	existence	NN
cord-321013-8pkrg0mx	94	3	of	of	IN
cord-321013-8pkrg0mx	94	4	transient	transient	JJ
cord-321013-8pkrg0mx	94	5	self	self	NN
cord-321013-8pkrg0mx	94	6	-	-	HYPH
cord-321013-8pkrg0mx	94	7	association	association	NN
cord-321013-8pkrg0mx	94	8	between	between	IN
cord-321013-8pkrg0mx	94	9	dimers	dimer	NNS
cord-321013-8pkrg0mx	94	10	in	in	IN
cord-321013-8pkrg0mx	94	11	solution	solution	NN
cord-321013-8pkrg0mx	94	12	was	be	VBD
cord-321013-8pkrg0mx	94	13	confirmed	confirm	VBN
cord-321013-8pkrg0mx	94	14	using	use	VBG
cord-321013-8pkrg0mx	94	15	a	a	DT
cord-321013-8pkrg0mx	94	16	disulphide	disulphide	JJ
cord-321013-8pkrg0mx	94	17	trapping	trapping	NN
cord-321013-8pkrg0mx	94	18	technique	technique	NN
cord-321013-8pkrg0mx	94	19	,	,	,
cord-321013-8pkrg0mx	94	20	and	and	CC
cord-321013-8pkrg0mx	94	21	it	-PRON-	PRP
cord-321013-8pkrg0mx	94	22	was	be	VBD
cord-321013-8pkrg0mx	94	23	shown	show	VBN
cord-321013-8pkrg0mx	94	24	that	that	IN
cord-321013-8pkrg0mx	94	25	by	by	IN
cord-321013-8pkrg0mx	94	26	neutralization	neutralization	NN
cord-321013-8pkrg0mx	94	27	of	of	IN
cord-321013-8pkrg0mx	94	28	excessive	excessive	JJ
cord-321013-8pkrg0mx	94	29	charges	charge	NNS
cord-321013-8pkrg0mx	94	30	on	on	IN
cord-321013-8pkrg0mx	94	31	the	the	DT
cord-321013-8pkrg0mx	94	32	protein	protein	NN
cord-321013-8pkrg0mx	94	33	,	,	,
cord-321013-8pkrg0mx	94	34	either	either	CC
cord-321013-8pkrg0mx	94	35	through	through	IN
cord-321013-8pkrg0mx	94	36	environmental	environmental	JJ
cord-321013-8pkrg0mx	94	37	charge	charge	NN
cord-321013-8pkrg0mx	94	38	screening	screening	NN
cord-321013-8pkrg0mx	94	39	or	or	CC
cord-321013-8pkrg0mx	94	40	charge	charge	NN
cord-321013-8pkrg0mx	94	41	modifications	modification	NNS
cord-321013-8pkrg0mx	94	42	,	,	,
cord-321013-8pkrg0mx	94	43	this	this	DT
cord-321013-8pkrg0mx	94	44	transient	transient	JJ
cord-321013-8pkrg0mx	94	45	self	self	NN
cord-321013-8pkrg0mx	94	46	-	-	HYPH
cord-321013-8pkrg0mx	94	47	association	association	NN
cord-321013-8pkrg0mx	94	48	can	can	MD
cord-321013-8pkrg0mx	94	49	be	be	VB
cord-321013-8pkrg0mx	94	50	regulated	regulate	VBN
cord-321013-8pkrg0mx	94	51	[	[	-LRB-
cord-321013-8pkrg0mx	94	52	44	44	CD
cord-321013-8pkrg0mx	94	53	]	]	-RRB-
cord-321013-8pkrg0mx	94	54	.	.	.
cord-321013-8pkrg0mx	95	1	This	this	DT
cord-321013-8pkrg0mx	95	2	proposed	propose	VBN
cord-321013-8pkrg0mx	95	3	biophysical	biophysical	JJ
cord-321013-8pkrg0mx	95	4	mechanism	mechanism	NN
cord-321013-8pkrg0mx	95	5	whereby	whereby	WRB
cord-321013-8pkrg0mx	95	6	electrostatic	electrostatic	JJ
cord-321013-8pkrg0mx	95	7	repulsion	repulsion	NN
cord-321013-8pkrg0mx	95	8	between	between	IN
cord-321013-8pkrg0mx	95	9	N	n	CD
cord-321013-8pkrg0mx	95	10	protein	protein	NN
cord-321013-8pkrg0mx	95	11	molecules	molecule	NNS
cord-321013-8pkrg0mx	95	12	acts	act	VBZ
cord-321013-8pkrg0mx	95	13	as	as	IN
cord-321013-8pkrg0mx	95	14	an	an	DT
cord-321013-8pkrg0mx	95	15	oligomerization	oligomerization	NN
cord-321013-8pkrg0mx	95	16	switch	switch	NN
cord-321013-8pkrg0mx	95	17	has	have	VBZ
cord-321013-8pkrg0mx	95	18	implications	implication	NNS
cord-321013-8pkrg0mx	95	19	for	for	IN
cord-321013-8pkrg0mx	95	20	understanding	understand	VBG
cord-321013-8pkrg0mx	95	21	how	how	WRB
cord-321013-8pkrg0mx	95	22	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	95	23	assembly	assembly	NNP
cord-321013-8pkrg0mx	95	24	is	be	VBZ
cord-321013-8pkrg0mx	95	25	then	then	RB
cord-321013-8pkrg0mx	95	26	subsequently	subsequently	RB
cord-321013-8pkrg0mx	95	27	modulated	modulate	VBD
cord-321013-8pkrg0mx	95	28	[	[	-LRB-
cord-321013-8pkrg0mx	95	29	44	44	CD
cord-321013-8pkrg0mx	95	30	]	]	-RRB-
cord-321013-8pkrg0mx	95	31	.	.	.
cord-321013-8pkrg0mx	96	1	In	in	IN
cord-321013-8pkrg0mx	96	2	addition	addition	NN
cord-321013-8pkrg0mx	96	3	,	,	,
cord-321013-8pkrg0mx	96	4	the	the	DT
cord-321013-8pkrg0mx	96	5	CTD	CTD	NNP
cord-321013-8pkrg0mx	96	6	45	45	CD
cord-321013-8pkrg0mx	96	7	residues	residue	NNS
cord-321013-8pkrg0mx	96	8	of	of	IN
cord-321013-8pkrg0mx	96	9	the	the	DT
cord-321013-8pkrg0mx	96	10	MHV	MHV	NNP
cord-321013-8pkrg0mx	96	11	N	N	NNP
cord-321013-8pkrg0mx	96	12	protein	protein	NN
cord-321013-8pkrg0mx	96	13	have	have	VBP
cord-321013-8pkrg0mx	96	14	been	be	VBN
cord-321013-8pkrg0mx	96	15	shown	show	VBN
cord-321013-8pkrg0mx	96	16	to	to	TO
cord-321013-8pkrg0mx	96	17	be	be	VB
cord-321013-8pkrg0mx	96	18	the	the	DT
cord-321013-8pkrg0mx	96	19	major	major	JJ
cord-321013-8pkrg0mx	96	20	determinant	determinant	NN
cord-321013-8pkrg0mx	96	21	for	for	IN
cord-321013-8pkrg0mx	96	22	interaction	interaction	NN
cord-321013-8pkrg0mx	96	23	with	with	IN
cord-321013-8pkrg0mx	96	24	the	the	DT
cord-321013-8pkrg0mx	96	25	M	M	NNP
cord-321013-8pkrg0mx	96	26	protein	protein	NN
cord-321013-8pkrg0mx	96	27	[	[	-LRB-
cord-321013-8pkrg0mx	96	28	61	61	CD
cord-321013-8pkrg0mx	96	29	]	]	-RRB-
cord-321013-8pkrg0mx	96	30	,	,	,
cord-321013-8pkrg0mx	96	31	and	and	CC
cord-321013-8pkrg0mx	96	32	so	so	RB
cord-321013-8pkrg0mx	96	33	association	association	NN
cord-321013-8pkrg0mx	96	34	of	of	IN
cord-321013-8pkrg0mx	96	35	the	the	DT
cord-321013-8pkrg0mx	96	36	N	N	NNP
cord-321013-8pkrg0mx	96	37	protein	protein	NN
cord-321013-8pkrg0mx	96	38	with	with	IN
cord-321013-8pkrg0mx	96	39	the	the	DT
cord-321013-8pkrg0mx	96	40	M	M	NNP
cord-321013-8pkrg0mx	96	41	protein	protein	NN
cord-321013-8pkrg0mx	96	42	may	may	MD
cord-321013-8pkrg0mx	96	43	also	also	RB
cord-321013-8pkrg0mx	96	44	play	play	VB
cord-321013-8pkrg0mx	96	45	a	a	DT
cord-321013-8pkrg0mx	96	46	role	role	NN
cord-321013-8pkrg0mx	96	47	in	in	IN
cord-321013-8pkrg0mx	96	48	the	the	DT
cord-321013-8pkrg0mx	96	49	assembly	assembly	NN
cord-321013-8pkrg0mx	96	50	of	of	IN
cord-321013-8pkrg0mx	96	51	the	the	DT
cord-321013-8pkrg0mx	96	52	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	96	53	core	core	NNP
cord-321013-8pkrg0mx	96	54	into	into	IN
cord-321013-8pkrg0mx	96	55	a	a	DT
cord-321013-8pkrg0mx	96	56	progeny	progeny	JJ
cord-321013-8pkrg0mx	96	57	virion	virion	NN
cord-321013-8pkrg0mx	96	58	[	[	-LRB-
cord-321013-8pkrg0mx	96	59	47	47	CD
cord-321013-8pkrg0mx	96	60	]	]	-RRB-
cord-321013-8pkrg0mx	96	61	.	.	.
cord-321013-8pkrg0mx	97	1	Oligomerization	Oligomerization	NNP
cord-321013-8pkrg0mx	97	2	via	via	IN
cord-321013-8pkrg0mx	97	3	the	the	DT
cord-321013-8pkrg0mx	97	4	CTD	CTD	NNP
cord-321013-8pkrg0mx	97	5	has	have	VBZ
cord-321013-8pkrg0mx	97	6	also	also	RB
cord-321013-8pkrg0mx	97	7	been	be	VBN
cord-321013-8pkrg0mx	97	8	reported	report	VBN
cord-321013-8pkrg0mx	97	9	in	in	IN
cord-321013-8pkrg0mx	97	10	human	human	JJ
cord-321013-8pkrg0mx	97	11	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	97	12	229E	229e	CD
cord-321013-8pkrg0mx	97	13	(	(	-LRB-
cord-321013-8pkrg0mx	97	14	hCoV-229E	hCoV-229E	NNP
cord-321013-8pkrg0mx	97	15	)	)	-RRB-
cord-321013-8pkrg0mx	97	16	and	and	CC
cord-321013-8pkrg0mx	97	17	a	a	DT
cord-321013-8pkrg0mx	97	18	recent	recent	JJ
cord-321013-8pkrg0mx	97	19	study	study	NN
cord-321013-8pkrg0mx	97	20	has	have	VBZ
cord-321013-8pkrg0mx	97	21	shown	show	VBN
cord-321013-8pkrg0mx	97	22	that	that	IN
cord-321013-8pkrg0mx	97	23	the	the	DT
cord-321013-8pkrg0mx	97	24	C	C	NNP
cord-321013-8pkrg0mx	97	25	-	-	HYPH
cord-321013-8pkrg0mx	97	26	terminal	terminal	NN
cord-321013-8pkrg0mx	97	27	tail	tail	NN
cord-321013-8pkrg0mx	97	28	peptide	peptide	NN
cord-321013-8pkrg0mx	97	29	,	,	,
cord-321013-8pkrg0mx	97	30	an	an	DT
cord-321013-8pkrg0mx	97	31	intrinsically	intrinsically	RB
cord-321013-8pkrg0mx	97	32	disordered	disordered	JJ
cord-321013-8pkrg0mx	97	33	domain	domain	NN
cord-321013-8pkrg0mx	97	34	that	that	WDT
cord-321013-8pkrg0mx	97	35	flanks	flank	VBZ
cord-321013-8pkrg0mx	97	36	the	the	DT
cord-321013-8pkrg0mx	97	37	CTD	CTD	NNP
cord-321013-8pkrg0mx	97	38	,	,	,
cord-321013-8pkrg0mx	97	39	plays	play	VBZ
cord-321013-8pkrg0mx	97	40	an	an	DT
cord-321013-8pkrg0mx	97	41	important	important	JJ
cord-321013-8pkrg0mx	97	42	role	role	NN
cord-321013-8pkrg0mx	97	43	in	in	IN
cord-321013-8pkrg0mx	97	44	dimer	dimer	NN
cord-321013-8pkrg0mx	97	45	-	-	HYPH
cord-321013-8pkrg0mx	97	46	dimer	dimer	NN
cord-321013-8pkrg0mx	97	47	association	association	NN
cord-321013-8pkrg0mx	97	48	[	[	-LRB-
cord-321013-8pkrg0mx	97	49	53	53	CD
cord-321013-8pkrg0mx	97	50	]	]	-RRB-
cord-321013-8pkrg0mx	97	51	.	.	.
cord-321013-8pkrg0mx	98	1	The	the	DT
cord-321013-8pkrg0mx	98	2	C	c	NN
cord-321013-8pkrg0mx	98	3	-	-	HYPH
cord-321013-8pkrg0mx	98	4	terminal	terminal	NN
cord-321013-8pkrg0mx	98	5	tail	tail	NN
cord-321013-8pkrg0mx	98	6	interferes	interfere	VBZ
cord-321013-8pkrg0mx	98	7	with	with	IN
cord-321013-8pkrg0mx	98	8	oligomerization	oligomerization	NN
cord-321013-8pkrg0mx	98	9	of	of	IN
cord-321013-8pkrg0mx	98	10	the	the	DT
cord-321013-8pkrg0mx	98	11	CTD	CTD	NNP
cord-321013-8pkrg0mx	98	12	and	and	CC
cord-321013-8pkrg0mx	98	13	has	have	VBZ
cord-321013-8pkrg0mx	98	14	an	an	DT
cord-321013-8pkrg0mx	98	15	inhibitory	inhibitory	JJ
cord-321013-8pkrg0mx	98	16	effect	effect	NN
cord-321013-8pkrg0mx	98	17	on	on	IN
cord-321013-8pkrg0mx	98	18	viral	viral	JJ
cord-321013-8pkrg0mx	98	19	titer	titer	NN
cord-321013-8pkrg0mx	98	20	of	of	IN
cord-321013-8pkrg0mx	98	21	HCoV-229E	HCoV-229E	NNP
cord-321013-8pkrg0mx	98	22	;	;	:
cord-321013-8pkrg0mx	98	23	and	and	CC
cord-321013-8pkrg0mx	98	24	further	further	RB
cord-321013-8pkrg0mx	98	25	understanding	understand	VBG
cord-321013-8pkrg0mx	98	26	this	this	DT
cord-321013-8pkrg0mx	98	27	mechanism	mechanism	NN
cord-321013-8pkrg0mx	98	28	of	of	IN
cord-321013-8pkrg0mx	98	29	oligomerization	oligomerization	NN
cord-321013-8pkrg0mx	98	30	may	may	MD
cord-321013-8pkrg0mx	98	31	provide	provide	VB
cord-321013-8pkrg0mx	98	32	insight	insight	NN
cord-321013-8pkrg0mx	98	33	into	into	IN
cord-321013-8pkrg0mx	98	34	the	the	DT
cord-321013-8pkrg0mx	98	35	viral	viral	JJ
cord-321013-8pkrg0mx	98	36	assembly	assembly	NN
cord-321013-8pkrg0mx	98	37	process	process	NN
cord-321013-8pkrg0mx	98	38	and	and	CC
cord-321013-8pkrg0mx	98	39	could	could	MD
cord-321013-8pkrg0mx	98	40	identify	identify	VB
cord-321013-8pkrg0mx	98	41	additional	additional	JJ
cord-321013-8pkrg0mx	98	42	targets	target	NNS
cord-321013-8pkrg0mx	98	43	for	for	IN
cord-321013-8pkrg0mx	98	44	drugs	drug	NNS
cord-321013-8pkrg0mx	98	45	to	to	TO
cord-321013-8pkrg0mx	98	46	combat	combat	VB
cord-321013-8pkrg0mx	98	47	CoVs	CoVs	NNP
cord-321013-8pkrg0mx	98	48	through	through	IN
cord-321013-8pkrg0mx	98	49	the	the	DT
cord-321013-8pkrg0mx	98	50	disruption	disruption	NN
cord-321013-8pkrg0mx	98	51	of	of	IN
cord-321013-8pkrg0mx	98	52	the	the	DT
cord-321013-8pkrg0mx	98	53	N	N	NNP
cord-321013-8pkrg0mx	98	54	protein	protein	NN
cord-321013-8pkrg0mx	98	55	self	self	NN
cord-321013-8pkrg0mx	98	56	-	-	HYPH
cord-321013-8pkrg0mx	98	57	association	association	NN
cord-321013-8pkrg0mx	98	58	[	[	-LRB-
cord-321013-8pkrg0mx	98	59	53	53	CD
cord-321013-8pkrg0mx	98	60	]	]	-RRB-
cord-321013-8pkrg0mx	98	61	.	.	.
cord-321013-8pkrg0mx	99	1	The	the	DT
cord-321013-8pkrg0mx	99	2	CTD	CTD	NNP
cord-321013-8pkrg0mx	99	3	of	of	IN
cord-321013-8pkrg0mx	99	4	SARS	SARS	NNP
cord-321013-8pkrg0mx	99	5	-	-	HYPH
cord-321013-8pkrg0mx	99	6	N	N	NNP
cord-321013-8pkrg0mx	99	7	(	(	-LRB-
cord-321013-8pkrg0mx	99	8	aa	aa	NNP
cord-321013-8pkrg0mx	99	9	251	251	CD
cord-321013-8pkrg0mx	99	10	-	-	HYPH
cord-321013-8pkrg0mx	99	11	422	422	CD
cord-321013-8pkrg0mx	99	12	)	)	-RRB-
cord-321013-8pkrg0mx	99	13	is	be	VBZ
cord-321013-8pkrg0mx	99	14	also	also	RB
cord-321013-8pkrg0mx	99	15	responsible	responsible	JJ
cord-321013-8pkrg0mx	99	16	for	for	IN
cord-321013-8pkrg0mx	99	17	stress	stress	NN
cord-321013-8pkrg0mx	99	18	granule	granule	NN
cord-321013-8pkrg0mx	99	19	localization	localization	NN
cord-321013-8pkrg0mx	99	20	that	that	WDT
cord-321013-8pkrg0mx	99	21	occurs	occur	VBZ
cord-321013-8pkrg0mx	99	22	as	as	IN
cord-321013-8pkrg0mx	99	23	part	part	NN
cord-321013-8pkrg0mx	99	24	of	of	IN
cord-321013-8pkrg0mx	99	25	an	an	DT
cord-321013-8pkrg0mx	99	26	integrated	integrated	JJ
cord-321013-8pkrg0mx	99	27	stress	stress	NN
cord-321013-8pkrg0mx	99	28	response	response	NN
cord-321013-8pkrg0mx	99	29	in	in	IN
cord-321013-8pkrg0mx	99	30	arsenite	arsenite	NNP
cord-321013-8pkrg0mx	99	31	-	-	HYPH
cord-321013-8pkrg0mx	99	32	treated	treat	VBN
cord-321013-8pkrg0mx	99	33	HeLa	HeLa	NNP
cord-321013-8pkrg0mx	99	34	cells	cell	NNS
cord-321013-8pkrg0mx	99	35	[	[	-LRB-
cord-321013-8pkrg0mx	99	36	38	38	CD
cord-321013-8pkrg0mx	99	37	]	]	-RRB-
cord-321013-8pkrg0mx	99	38	.	.	.
cord-321013-8pkrg0mx	100	1	Once	once	RB
cord-321013-8pkrg0mx	100	2	sequestered	sequester	VBN
cord-321013-8pkrg0mx	100	3	in	in	IN
cord-321013-8pkrg0mx	100	4	these	these	DT
cord-321013-8pkrg0mx	100	5	granules	granule	NNS
cord-321013-8pkrg0mx	100	6	,	,	,
cord-321013-8pkrg0mx	100	7	the	the	DT
cord-321013-8pkrg0mx	100	8	N	n	CD
cord-321013-8pkrg0mx	100	9	protein	protein	NN
cord-321013-8pkrg0mx	100	10	can	can	MD
cord-321013-8pkrg0mx	100	11	induce	induce	VB
cord-321013-8pkrg0mx	100	12	host	host	NN
cord-321013-8pkrg0mx	100	13	translational	translational	JJ
cord-321013-8pkrg0mx	100	14	shutoff	shutoff	NN
cord-321013-8pkrg0mx	100	15	.	.	.
cord-321013-8pkrg0mx	101	1	The	the	DT
cord-321013-8pkrg0mx	101	2	NTD	NTD	NNP
cord-321013-8pkrg0mx	101	3	and	and	CC
cord-321013-8pkrg0mx	101	4	the	the	DT
cord-321013-8pkrg0mx	101	5	CTD	CTD	NNP
cord-321013-8pkrg0mx	101	6	are	be	VBP
cord-321013-8pkrg0mx	101	7	interspersed	intersperse	VBN
cord-321013-8pkrg0mx	101	8	by	by	IN
cord-321013-8pkrg0mx	101	9	intrinsically	intrinsically	RB
cord-321013-8pkrg0mx	101	10	disordered	disordered	JJ
cord-321013-8pkrg0mx	101	11	regions	region	NNS
cord-321013-8pkrg0mx	101	12	(	(	-LRB-
cord-321013-8pkrg0mx	101	13	IDRs	IDRs	NNP
cord-321013-8pkrg0mx	101	14	)	)	-RRB-
cord-321013-8pkrg0mx	101	15	[	[	-LRB-
cord-321013-8pkrg0mx	101	16	19	19	CD
cord-321013-8pkrg0mx	101	17	,	,	,
cord-321013-8pkrg0mx	101	18	37	37	CD
cord-321013-8pkrg0mx	101	19	]	]	-RRB-
cord-321013-8pkrg0mx	101	20	.	.	.
cord-321013-8pkrg0mx	102	1	Intrinsically	intrinsically	RB
cord-321013-8pkrg0mx	102	2	disordered	disordered	JJ
cord-321013-8pkrg0mx	102	3	proteins	protein	NNS
cord-321013-8pkrg0mx	102	4	(	(	-LRB-
cord-321013-8pkrg0mx	102	5	IDPs	IDPs	NNP
cord-321013-8pkrg0mx	102	6	)	)	-RRB-
cord-321013-8pkrg0mx	102	7	or	or	CC
cord-321013-8pkrg0mx	102	8	IDRs	idr	NNS
cord-321013-8pkrg0mx	102	9	lack	lack	VBP
cord-321013-8pkrg0mx	102	10	a	a	DT
cord-321013-8pkrg0mx	102	11	tertiary	tertiary	JJ
cord-321013-8pkrg0mx	102	12	structure	structure	NN
cord-321013-8pkrg0mx	102	13	and	and	CC
cord-321013-8pkrg0mx	102	14	have	have	VBP
cord-321013-8pkrg0mx	102	15	no	no	DT
cord-321013-8pkrg0mx	102	16	fixed	fix	VBN
cord-321013-8pkrg0mx	102	17	3-dimentional	3-dimentional	CD
cord-321013-8pkrg0mx	102	18	shape	shape	NN
cord-321013-8pkrg0mx	102	19	in	in	IN
cord-321013-8pkrg0mx	102	20	the	the	DT
cord-321013-8pkrg0mx	102	21	native	native	JJ
cord-321013-8pkrg0mx	102	22	form	form	NN
cord-321013-8pkrg0mx	102	23	.	.	.
cord-321013-8pkrg0mx	103	1	However	however	RB
cord-321013-8pkrg0mx	103	2	,	,	,
cord-321013-8pkrg0mx	103	3	IDPs	IDPs	NNP
cord-321013-8pkrg0mx	103	4	and	and	CC
cord-321013-8pkrg0mx	103	5	IDRs	idr	NNS
cord-321013-8pkrg0mx	103	6	play	play	VBP
cord-321013-8pkrg0mx	103	7	a	a	DT
cord-321013-8pkrg0mx	103	8	role	role	NN
cord-321013-8pkrg0mx	103	9	in	in	IN
cord-321013-8pkrg0mx	103	10	various	various	JJ
cord-321013-8pkrg0mx	103	11	biological	biological	JJ
cord-321013-8pkrg0mx	103	12	functions	function	NNS
cord-321013-8pkrg0mx	103	13	including	include	VBG
cord-321013-8pkrg0mx	103	14	DNA	DNA	NNP
cord-321013-8pkrg0mx	103	15	,	,	,
cord-321013-8pkrg0mx	103	16	RNA	RNA	NNP
cord-321013-8pkrg0mx	103	17	and	and	CC
cord-321013-8pkrg0mx	103	18	protein	protein	NN
cord-321013-8pkrg0mx	103	19	binding	bind	VBG
cord-321013-8pkrg0mx	103	20	with	with	IN
cord-321013-8pkrg0mx	103	21	the	the	DT
cord-321013-8pkrg0mx	103	22	disordered	disordered	JJ
cord-321013-8pkrg0mx	103	23	regions	region	NNS
cord-321013-8pkrg0mx	103	24	facilitating	facilitate	VBG
cord-321013-8pkrg0mx	103	25	access	access	NN
cord-321013-8pkrg0mx	103	26	to	to	IN
cord-321013-8pkrg0mx	103	27	these	these	DT
cord-321013-8pkrg0mx	103	28	binding	bind	VBG
cord-321013-8pkrg0mx	103	29	sites	site	NNS
cord-321013-8pkrg0mx	103	30	[	[	-LRB-
cord-321013-8pkrg0mx	103	31	62	62	CD
cord-321013-8pkrg0mx	103	32	]	]	-RRB-
cord-321013-8pkrg0mx	103	33	[	[	-LRB-
cord-321013-8pkrg0mx	103	34	63	63	CD
cord-321013-8pkrg0mx	103	35	]	]	-RRB-
cord-321013-8pkrg0mx	103	36	[	[	-LRB-
cord-321013-8pkrg0mx	103	37	64	64	CD
cord-321013-8pkrg0mx	103	38	]	]	-RRB-
cord-321013-8pkrg0mx	103	39	.	.	.
cord-321013-8pkrg0mx	104	1	In	in	IN
cord-321013-8pkrg0mx	104	2	fact	fact	NN
cord-321013-8pkrg0mx	104	3	,	,	,
cord-321013-8pkrg0mx	104	4	the	the	DT
cord-321013-8pkrg0mx	104	5	three	three	CD
cord-321013-8pkrg0mx	104	6	IDRs	IDRs	NNPS
cord-321013-8pkrg0mx	104	7	in	in	IN
cord-321013-8pkrg0mx	104	8	SARS	SARS	NNP
cord-321013-8pkrg0mx	104	9	-	-	HYPH
cord-321013-8pkrg0mx	104	10	N	N	NNP
cord-321013-8pkrg0mx	104	11	(	(	-LRB-
cord-321013-8pkrg0mx	104	12	aa	aa	NNP
cord-321013-8pkrg0mx	104	13	1	1	NNP
cord-321013-8pkrg0mx	104	14	-	-	SYM
cord-321013-8pkrg0mx	104	15	44	44	CD
cord-321013-8pkrg0mx	104	16	,	,	,
cord-321013-8pkrg0mx	104	17	182	182	CD
cord-321013-8pkrg0mx	104	18	-	-	SYM
cord-321013-8pkrg0mx	104	19	247	247	CD
cord-321013-8pkrg0mx	104	20	and	and	CC
cord-321013-8pkrg0mx	104	21	366	366	CD
cord-321013-8pkrg0mx	104	22	-	-	SYM
cord-321013-8pkrg0mx	104	23	422	422	CD
cord-321013-8pkrg0mx	104	24	)	)	-RRB-
cord-321013-8pkrg0mx	104	25	have	have	VBP
cord-321013-8pkrg0mx	104	26	all	all	DT
cord-321013-8pkrg0mx	104	27	been	be	VBN
cord-321013-8pkrg0mx	104	28	shown	show	VBN
cord-321013-8pkrg0mx	104	29	to	to	TO
cord-321013-8pkrg0mx	104	30	modulate	modulate	VB
cord-321013-8pkrg0mx	104	31	the	the	DT
cord-321013-8pkrg0mx	104	32	RND	rnd	NN
cord-321013-8pkrg0mx	104	33	-	-	HYPH
cord-321013-8pkrg0mx	104	34	binding	bind	VBG
cord-321013-8pkrg0mx	104	35	activity	activity	NN
cord-321013-8pkrg0mx	104	36	of	of	IN
cord-321013-8pkrg0mx	104	37	the	the	DT
cord-321013-8pkrg0mx	104	38	NTD	NTD	NNP
cord-321013-8pkrg0mx	104	39	and	and	CC
cord-321013-8pkrg0mx	104	40	CTD	CTD	NNP
cord-321013-8pkrg0mx	104	41	[	[	-LRB-
cord-321013-8pkrg0mx	104	42	19	19	CD
cord-321013-8pkrg0mx	104	43	,	,	,
cord-321013-8pkrg0mx	104	44	37	37	CD
cord-321013-8pkrg0mx	104	45	]	]	-RRB-
cord-321013-8pkrg0mx	104	46	.	.	.
cord-321013-8pkrg0mx	105	1	Moreover	moreover	RB
cord-321013-8pkrg0mx	105	2	,	,	,
cord-321013-8pkrg0mx	105	3	both	both	CC
cord-321013-8pkrg0mx	105	4	the	the	DT
cord-321013-8pkrg0mx	105	5	middle	middle	NN
cord-321013-8pkrg0mx	105	6	and	and	CC
cord-321013-8pkrg0mx	105	7	C	c	NN
cord-321013-8pkrg0mx	105	8	-	-	HYPH
cord-321013-8pkrg0mx	105	9	terminal	terminal	NN
cord-321013-8pkrg0mx	105	10	IDRs	idr	NNS
cord-321013-8pkrg0mx	105	11	(	(	-LRB-
cord-321013-8pkrg0mx	105	12	Figure	figure	NN
cord-321013-8pkrg0mx	105	13	1	1	CD
cord-321013-8pkrg0mx	105	14	)	)	-RRB-
cord-321013-8pkrg0mx	105	15	have	have	VBP
cord-321013-8pkrg0mx	105	16	been	be	VBN
cord-321013-8pkrg0mx	105	17	implicated	implicate	VBN
cord-321013-8pkrg0mx	105	18	in	in	IN
cord-321013-8pkrg0mx	105	19	the	the	DT
cord-321013-8pkrg0mx	105	20	oligomerization	oligomerization	NN
cord-321013-8pkrg0mx	105	21	of	of	IN
cord-321013-8pkrg0mx	105	22	the	the	DT
cord-321013-8pkrg0mx	105	23	N	N	NNP
cord-321013-8pkrg0mx	105	24	protein	protein	NN
cord-321013-8pkrg0mx	105	25	[	[	-LRB-
cord-321013-8pkrg0mx	105	26	44	44	CD
cord-321013-8pkrg0mx	105	27	,	,	,
cord-321013-8pkrg0mx	105	28	65	65	CD
cord-321013-8pkrg0mx	105	29	]	]	-RRB-
cord-321013-8pkrg0mx	105	30	,	,	,
cord-321013-8pkrg0mx	105	31	with	with	IN
cord-321013-8pkrg0mx	105	32	the	the	DT
cord-321013-8pkrg0mx	105	33	middle	middle	JJ
cord-321013-8pkrg0mx	105	34	IDR	IDR	NNP
cord-321013-8pkrg0mx	105	35	also	also	RB
cord-321013-8pkrg0mx	105	36	associated	associate	VBD
cord-321013-8pkrg0mx	105	37	with	with	IN
cord-321013-8pkrg0mx	105	38	N	n	CD
cord-321013-8pkrg0mx	105	39	protein	protein	NN
cord-321013-8pkrg0mx	105	40	functionality	functionality	NN
cord-321013-8pkrg0mx	105	41	and	and	CC
cord-321013-8pkrg0mx	105	42	N	N	NNP
cord-321013-8pkrg0mx	105	43	-	-	HYPH
cord-321013-8pkrg0mx	105	44	M	M	NNP
cord-321013-8pkrg0mx	105	45	interaction	interaction	NN
cord-321013-8pkrg0mx	105	46	[	[	-LRB-
cord-321013-8pkrg0mx	105	47	19	19	CD
cord-321013-8pkrg0mx	105	48	,	,	,
cord-321013-8pkrg0mx	105	49	39	39	CD
cord-321013-8pkrg0mx	105	50	,	,	,
cord-321013-8pkrg0mx	105	51	40	40	CD
cord-321013-8pkrg0mx	105	52	,	,	,
cord-321013-8pkrg0mx	105	53	66	66	CD
cord-321013-8pkrg0mx	105	54	]	]	-RRB-
cord-321013-8pkrg0mx	105	55	.	.	.
cord-321013-8pkrg0mx	106	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	106	2	would	would	MD
cord-321013-8pkrg0mx	106	3	be	be	VB
cord-321013-8pkrg0mx	106	4	interesting	interesting	JJ
cord-321013-8pkrg0mx	106	5	to	to	TO
cord-321013-8pkrg0mx	106	6	determine	determine	VB
cord-321013-8pkrg0mx	106	7	whether	whether	IN
cord-321013-8pkrg0mx	106	8	the	the	DT
cord-321013-8pkrg0mx	106	9	presence	presence	NN
cord-321013-8pkrg0mx	106	10	of	of	IN
cord-321013-8pkrg0mx	106	11	three	three	CD
cord-321013-8pkrg0mx	106	12	disordered	disordered	JJ
cord-321013-8pkrg0mx	106	13	regions	region	NNS
cord-321013-8pkrg0mx	106	14	in	in	IN
cord-321013-8pkrg0mx	106	15	SARS	SARS	NNP
cord-321013-8pkrg0mx	106	16	N	N	NNP
cord-321013-8pkrg0mx	106	17	,	,	,
cord-321013-8pkrg0mx	106	18	compared	compare	VBN
cord-321013-8pkrg0mx	106	19	to	to	IN
cord-321013-8pkrg0mx	106	20	the	the	DT
cord-321013-8pkrg0mx	106	21	one	one	CD
cord-321013-8pkrg0mx	106	22	disordered	disordered	JJ
cord-321013-8pkrg0mx	106	23	region	region	NN
cord-321013-8pkrg0mx	106	24	in	in	IN
cord-321013-8pkrg0mx	106	25	HCoV	HCoV	NNP
cord-321013-8pkrg0mx	107	1	-NL63	-NL63	:
cord-321013-8pkrg0mx	107	2	N	N	NNP
cord-321013-8pkrg0mx	107	3	for	for	IN
cord-321013-8pkrg0mx	107	4	example	example	NN
cord-321013-8pkrg0mx	107	5	,	,	,
cord-321013-8pkrg0mx	107	6	would	would	MD
cord-321013-8pkrg0mx	107	7	result	result	VB
cord-321013-8pkrg0mx	107	8	in	in	IN
cord-321013-8pkrg0mx	107	9	SARS	SARS	NNP
cord-321013-8pkrg0mx	107	10	N	N	NNP
cord-321013-8pkrg0mx	107	11	having	have	VBG
cord-321013-8pkrg0mx	107	12	a	a	DT
cord-321013-8pkrg0mx	107	13	higher	high	JJR
cord-321013-8pkrg0mx	107	14	binding	bind	VBG
cord-321013-8pkrg0mx	107	15	affinity	affinity	NN
cord-321013-8pkrg0mx	107	16	to	to	IN
cord-321013-8pkrg0mx	107	17	viral	viral	JJ
cord-321013-8pkrg0mx	107	18	,	,	,
cord-321013-8pkrg0mx	107	19	as	as	RB
cord-321013-8pkrg0mx	107	20	well	well	RB
cord-321013-8pkrg0mx	107	21	as	as	IN
cord-321013-8pkrg0mx	107	22	host	host	NN
cord-321013-8pkrg0mx	107	23	cellular	cellular	JJ
cord-321013-8pkrg0mx	107	24	proteins	protein	NNS
cord-321013-8pkrg0mx	107	25	.	.	.
cord-321013-8pkrg0mx	108	1	If	if	IN
cord-321013-8pkrg0mx	108	2	indeed	indeed	RB
cord-321013-8pkrg0mx	108	3	so	so	RB
cord-321013-8pkrg0mx	108	4	,	,	,
cord-321013-8pkrg0mx	108	5	could	could	MD
cord-321013-8pkrg0mx	108	6	this	this	DT
cord-321013-8pkrg0mx	108	7	then	then	RB
cord-321013-8pkrg0mx	108	8	indicate	indicate	VB
cord-321013-8pkrg0mx	108	9	a	a	DT
cord-321013-8pkrg0mx	108	10	probable	probable	JJ
cord-321013-8pkrg0mx	108	11	basis	basis	NN
cord-321013-8pkrg0mx	108	12	for	for	IN
cord-321013-8pkrg0mx	108	13	the	the	DT
cord-321013-8pkrg0mx	108	14	increased	increase	VBN
cord-321013-8pkrg0mx	108	15	pathogenicity	pathogenicity	NN
cord-321013-8pkrg0mx	108	16	of	of	IN
cord-321013-8pkrg0mx	108	17	SARS	SARS	NNP
cord-321013-8pkrg0mx	108	18	-	-	HYPH
cord-321013-8pkrg0mx	108	19	CoV	CoV	NNP
cord-321013-8pkrg0mx	108	20	compared	compare	VBN
cord-321013-8pkrg0mx	108	21	to	to	IN
cord-321013-8pkrg0mx	108	22	HCoV	HCoV	NNP
cord-321013-8pkrg0mx	108	23	-	-	HYPH
cord-321013-8pkrg0mx	108	24	NL63	NL63	NNP
cord-321013-8pkrg0mx	108	25	?	?	.
cord-321013-8pkrg0mx	109	1	In	in	IN
cord-321013-8pkrg0mx	109	2	order	order	NN
cord-321013-8pkrg0mx	109	3	for	for	IN
cord-321013-8pkrg0mx	109	4	CoV	CoV	NNP
cord-321013-8pkrg0mx	109	5	N	n	CD
cord-321013-8pkrg0mx	109	6	proteins	protein	NNS
cord-321013-8pkrg0mx	109	7	to	to	TO
cord-321013-8pkrg0mx	109	8	package	package	VB
cord-321013-8pkrg0mx	109	9	the	the	DT
cord-321013-8pkrg0mx	109	10	viral	viral	JJ
cord-321013-8pkrg0mx	109	11	genome	genome	NN
cord-321013-8pkrg0mx	109	12	with	with	IN
cord-321013-8pkrg0mx	109	13	structural	structural	JJ
cord-321013-8pkrg0mx	109	14	proteins	protein	NNS
cord-321013-8pkrg0mx	109	15	to	to	TO
cord-321013-8pkrg0mx	109	16	form	form	VB
cord-321013-8pkrg0mx	109	17	ribonucleoprotein	ribonucleoprotein	NN
cord-321013-8pkrg0mx	109	18	(	(	-LRB-
cord-321013-8pkrg0mx	109	19	RNP	RNP	NNP
cord-321013-8pkrg0mx	109	20	)	)	-RRB-
cord-321013-8pkrg0mx	109	21	complexes	complex	NNS
cord-321013-8pkrg0mx	109	22	for	for	IN
cord-321013-8pkrg0mx	109	23	viral	viral	JJ
cord-321013-8pkrg0mx	109	24	assembly	assembly	NN
cord-321013-8pkrg0mx	109	25	,	,	,
cord-321013-8pkrg0mx	109	26	two	two	CD
cord-321013-8pkrg0mx	109	27	key	key	JJ
cord-321013-8pkrg0mx	109	28	activities	activity	NNS
cord-321013-8pkrg0mx	109	29	are	be	VBP
cord-321013-8pkrg0mx	109	30	required	require	VBN
cord-321013-8pkrg0mx	109	31	:	:	:
cord-321013-8pkrg0mx	109	32	the	the	DT
cord-321013-8pkrg0mx	109	33	interaction	interaction	NN
cord-321013-8pkrg0mx	109	34	between	between	IN
cord-321013-8pkrg0mx	109	35	protein	protein	NN
cord-321013-8pkrg0mx	109	36	and	and	CC
cord-321013-8pkrg0mx	109	37	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	109	38	acid	acid	NN
cord-321013-8pkrg0mx	109	39	and	and	CC
cord-321013-8pkrg0mx	109	40	the	the	DT
cord-321013-8pkrg0mx	109	41	ability	ability	NN
cord-321013-8pkrg0mx	109	42	of	of	IN
cord-321013-8pkrg0mx	109	43	the	the	DT
cord-321013-8pkrg0mx	109	44	complex	complex	NN
cord-321013-8pkrg0mx	109	45	to	to	TO
cord-321013-8pkrg0mx	109	46	oligomerize	oligomerize	VB
cord-321013-8pkrg0mx	109	47	[	[	-LRB-
cord-321013-8pkrg0mx	109	48	58	58	CD
cord-321013-8pkrg0mx	109	49	]	]	-RRB-
cord-321013-8pkrg0mx	109	50	.	.	.
cord-321013-8pkrg0mx	110	1	The	the	DT
cord-321013-8pkrg0mx	110	2	N	n	CD
cord-321013-8pkrg0mx	110	3	proteins	protein	NNS
cord-321013-8pkrg0mx	110	4	of	of	IN
cord-321013-8pkrg0mx	110	5	SARS	SARS	NNP
cord-321013-8pkrg0mx	110	6	-	-	HYPH
cord-321013-8pkrg0mx	110	7	CoV	CoV	NNP
cord-321013-8pkrg0mx	110	8	,	,	,
cord-321013-8pkrg0mx	110	9	IBV	IBV	NNP
cord-321013-8pkrg0mx	110	10	and	and	CC
cord-321013-8pkrg0mx	110	11	MHV	MHV	NNP
cord-321013-8pkrg0mx	110	12	have	have	VBP
cord-321013-8pkrg0mx	110	13	all	all	DT
cord-321013-8pkrg0mx	110	14	been	be	VBN
cord-321013-8pkrg0mx	110	15	shown	show	VBN
cord-321013-8pkrg0mx	110	16	to	to	TO
cord-321013-8pkrg0mx	110	17	perform	perform	VB
cord-321013-8pkrg0mx	110	18	both	both	CC
cord-321013-8pkrg0mx	110	19	these	these	DT
cord-321013-8pkrg0mx	110	20	functions	function	NNS
cord-321013-8pkrg0mx	110	21	.	.	.
cord-321013-8pkrg0mx	111	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	111	2	-	-	HYPH
cord-321013-8pkrg0mx	111	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	111	4	-	-	HYPH
cord-321013-8pkrg0mx	111	5	N	N	NNP
cord-321013-8pkrg0mx	111	6	protein	protein	NN
cord-321013-8pkrg0mx	111	7	interacts	interact	VBZ
cord-321013-8pkrg0mx	111	8	with	with	IN
cord-321013-8pkrg0mx	111	9	RNA	RNA	NNP
cord-321013-8pkrg0mx	111	10	at	at	IN
cord-321013-8pkrg0mx	111	11	multiple	multiple	JJ
cord-321013-8pkrg0mx	111	12	sites	site	NNS
cord-321013-8pkrg0mx	111	13	,	,	,
cord-321013-8pkrg0mx	111	14	with	with	IN
cord-321013-8pkrg0mx	111	15	all	all	DT
cord-321013-8pkrg0mx	111	16	three	three	CD
cord-321013-8pkrg0mx	111	17	domains	domain	NNS
cord-321013-8pkrg0mx	111	18	having	have	VBG
cord-321013-8pkrg0mx	111	19	charged	charge	VBN
cord-321013-8pkrg0mx	111	20	regions	region	NNS
cord-321013-8pkrg0mx	111	21	[	[	-LRB-
cord-321013-8pkrg0mx	111	22	55	55	CD
cord-321013-8pkrg0mx	111	23	]	]	-RRB-
cord-321013-8pkrg0mx	111	24	.	.	.
cord-321013-8pkrg0mx	112	1	The	the	DT
cord-321013-8pkrg0mx	112	2	crystal	crystal	NN
cord-321013-8pkrg0mx	112	3	structures	structure	NNS
cord-321013-8pkrg0mx	112	4	of	of	IN
cord-321013-8pkrg0mx	112	5	the	the	DT
cord-321013-8pkrg0mx	112	6	NTD	NTD	NNP
cord-321013-8pkrg0mx	112	7	and	and	CC
cord-321013-8pkrg0mx	112	8	CTD	CTD	NNP
cord-321013-8pkrg0mx	112	9	domains	domain	NNS
cord-321013-8pkrg0mx	112	10	of	of	IN
cord-321013-8pkrg0mx	112	11	the	the	DT
cord-321013-8pkrg0mx	112	12	N	n	CD
cord-321013-8pkrg0mx	112	13	protein	protein	NN
cord-321013-8pkrg0mx	112	14	from	from	IN
cord-321013-8pkrg0mx	112	15	SARS	SARS	NNP
cord-321013-8pkrg0mx	112	16	-	-	HYPH
cord-321013-8pkrg0mx	112	17	CoV	CoV	NNP
cord-321013-8pkrg0mx	112	18	,	,	,
cord-321013-8pkrg0mx	112	19	IBV	IBV	NNP
cord-321013-8pkrg0mx	112	20	and	and	CC
cord-321013-8pkrg0mx	112	21	MHV	MHV	NNP
cord-321013-8pkrg0mx	112	22	all	all	DT
cord-321013-8pkrg0mx	112	23	share	share	VBP
cord-321013-8pkrg0mx	112	24	a	a	DT
cord-321013-8pkrg0mx	112	25	similar	similar	JJ
cord-321013-8pkrg0mx	112	26	overall	overall	NN
cord-321013-8pkrg0mx	112	27	and	and	CC
cord-321013-8pkrg0mx	112	28	topology	topology	NN
cord-321013-8pkrg0mx	112	29	structure	structure	NN
cord-321013-8pkrg0mx	112	30	,	,	,
cord-321013-8pkrg0mx	112	31	which	which	WDT
cord-321013-8pkrg0mx	112	32	corroborates	corroborate	VBZ
cord-321013-8pkrg0mx	112	33	a	a	DT
cord-321013-8pkrg0mx	112	34	conserved	conserved	JJ
cord-321013-8pkrg0mx	112	35	mechanism	mechanism	NN
cord-321013-8pkrg0mx	112	36	of	of	IN
cord-321013-8pkrg0mx	112	37	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	112	38	formation	formation	NN
cord-321013-8pkrg0mx	112	39	for	for	IN
cord-321013-8pkrg0mx	112	40	CoVs	CoVs	NNP
cord-321013-8pkrg0mx	112	41	[	[	-LRB-
cord-321013-8pkrg0mx	112	42	27	27	CD
cord-321013-8pkrg0mx	112	43	]	]	-RRB-
cord-321013-8pkrg0mx	112	44	.	.	.
cord-321013-8pkrg0mx	113	1	Furthermore	furthermore	RB
cord-321013-8pkrg0mx	113	2	,	,	,
cord-321013-8pkrg0mx	113	3	despite	despite	IN
cord-321013-8pkrg0mx	113	4	a	a	DT
cord-321013-8pkrg0mx	113	5	lack	lack	NN
cord-321013-8pkrg0mx	113	6	of	of	IN
cord-321013-8pkrg0mx	113	7	significant	significant	JJ
cord-321013-8pkrg0mx	113	8	sequence	sequence	NN
cord-321013-8pkrg0mx	113	9	similarity	similarity	NN
cord-321013-8pkrg0mx	113	10	,	,	,
cord-321013-8pkrg0mx	113	11	the	the	DT
cord-321013-8pkrg0mx	113	12	cSARS	cSARS	NNP
cord-321013-8pkrg0mx	113	13	-	-	HYPH
cord-321013-8pkrg0mx	113	14	N	N	NNP
cord-321013-8pkrg0mx	113	15	had	have	VBD
cord-321013-8pkrg0mx	113	16	a	a	DT
cord-321013-8pkrg0mx	113	17	similar	similar	JJ
cord-321013-8pkrg0mx	113	18	fold	fold	NN
cord-321013-8pkrg0mx	113	19	to	to	IN
cord-321013-8pkrg0mx	113	20	that	that	DT
cord-321013-8pkrg0mx	113	21	of	of	IN
cord-321013-8pkrg0mx	113	22	the	the	DT
cord-321013-8pkrg0mx	113	23	N	N	NNP
cord-321013-8pkrg0mx	113	24	protein	protein	NN
cord-321013-8pkrg0mx	113	25	of	of	IN
cord-321013-8pkrg0mx	113	26	porcine	porcine	JJ
cord-321013-8pkrg0mx	113	27	reproductive	reproductive	JJ
cord-321013-8pkrg0mx	113	28	and	and	CC
cord-321013-8pkrg0mx	113	29	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	113	30	syndrome	syndrome	NN
cord-321013-8pkrg0mx	113	31	virus	virus	NN
cord-321013-8pkrg0mx	113	32	,	,	,
cord-321013-8pkrg0mx	113	33	a	a	DT
cord-321013-8pkrg0mx	113	34	member	member	NN
cord-321013-8pkrg0mx	113	35	of	of	IN
cord-321013-8pkrg0mx	113	36	Arteriviridae	Arteriviridae	NNP
cord-321013-8pkrg0mx	113	37	family	family	NN
cord-321013-8pkrg0mx	113	38	,	,	,
cord-321013-8pkrg0mx	113	39	suggesting	suggest	VBG
cord-321013-8pkrg0mx	113	40	an	an	DT
cord-321013-8pkrg0mx	113	41	evolutionary	evolutionary	JJ
cord-321013-8pkrg0mx	113	42	link	link	NN
cord-321013-8pkrg0mx	113	43	between	between	IN
cord-321013-8pkrg0mx	113	44	Coronaviridae	Coronaviridae	NNP
cord-321013-8pkrg0mx	113	45	and	and	CC
cord-321013-8pkrg0mx	113	46	Arteriviridae	Arteriviridae	NNP
cord-321013-8pkrg0mx	113	47	in	in	IN
cord-321013-8pkrg0mx	113	48	which	which	WDT
cord-321013-8pkrg0mx	113	49	the	the	DT
cord-321013-8pkrg0mx	113	50	N	n	CD
cord-321013-8pkrg0mx	113	51	proteins	protein	NNS
cord-321013-8pkrg0mx	113	52	of	of	IN
cord-321013-8pkrg0mx	113	53	both	both	DT
cord-321013-8pkrg0mx	113	54	viruses	virus	NNS
cord-321013-8pkrg0mx	113	55	have	have	VBP
cord-321013-8pkrg0mx	113	56	a	a	DT
cord-321013-8pkrg0mx	113	57	common	common	JJ
cord-321013-8pkrg0mx	113	58	origin	origin	NN
cord-321013-8pkrg0mx	113	59	[	[	-LRB-
cord-321013-8pkrg0mx	113	60	47	47	CD
cord-321013-8pkrg0mx	113	61	]	]	-RRB-
cord-321013-8pkrg0mx	113	62	.	.	.
cord-321013-8pkrg0mx	114	1	In	in	IN
cord-321013-8pkrg0mx	114	2	fact	fact	NN
cord-321013-8pkrg0mx	114	3	,	,	,
cord-321013-8pkrg0mx	114	4	due	due	IN
cord-321013-8pkrg0mx	114	5	to	to	IN
cord-321013-8pkrg0mx	114	6	their	-PRON-	PRP$
cord-321013-8pkrg0mx	114	7	similar	similar	JJ
cord-321013-8pkrg0mx	114	8	genome	genome	NN
cord-321013-8pkrg0mx	114	9	organization	organization	NN
cord-321013-8pkrg0mx	114	10	and	and	CC
cord-321013-8pkrg0mx	114	11	viral	viral	JJ
cord-321013-8pkrg0mx	114	12	replication	replication	NN
cord-321013-8pkrg0mx	114	13	mechanisms	mechanism	NNS
cord-321013-8pkrg0mx	114	14	,	,	,
cord-321013-8pkrg0mx	114	15	the	the	DT
cord-321013-8pkrg0mx	114	16	Coronaviridae	Coronaviridae	NNP
cord-321013-8pkrg0mx	114	17	and	and	CC
cord-321013-8pkrg0mx	114	18	Arteriviridae	Arteriviridae	NNP
cord-321013-8pkrg0mx	114	19	were	be	VBD
cord-321013-8pkrg0mx	114	20	united	unite	VBN
cord-321013-8pkrg0mx	114	21	to	to	TO
cord-321013-8pkrg0mx	114	22	form	form	VB
cord-321013-8pkrg0mx	114	23	the	the	DT
cord-321013-8pkrg0mx	114	24	relatively	relatively	RB
cord-321013-8pkrg0mx	114	25	new	new	JJ
cord-321013-8pkrg0mx	114	26	order	order	NN
cord-321013-8pkrg0mx	114	27	Nidovirales	Nidovirales	NNP
cord-321013-8pkrg0mx	114	28	.	.	.
cord-321013-8pkrg0mx	115	1	In	in	IN
cord-321013-8pkrg0mx	115	2	virus	virus	NN
cord-321013-8pkrg0mx	115	3	-	-	HYPH
cord-321013-8pkrg0mx	115	4	infected	infect	VBN
cord-321013-8pkrg0mx	115	5	cells	cell	NNS
cord-321013-8pkrg0mx	115	6	,	,	,
cord-321013-8pkrg0mx	115	7	CoV	cov	NN
cord-321013-8pkrg0mx	115	8	N	n	CD
cord-321013-8pkrg0mx	115	9	proteins	protein	NNS
cord-321013-8pkrg0mx	115	10	can	can	MD
cord-321013-8pkrg0mx	115	11	localize	localize	VB
cord-321013-8pkrg0mx	115	12	to	to	IN
cord-321013-8pkrg0mx	115	13	the	the	DT
cord-321013-8pkrg0mx	115	14	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	115	15	alone	alone	RB
cord-321013-8pkrg0mx	115	16	or	or	CC
cord-321013-8pkrg0mx	115	17	to	to	IN
cord-321013-8pkrg0mx	115	18	the	the	DT
cord-321013-8pkrg0mx	115	19	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	115	20	and	and	CC
cord-321013-8pkrg0mx	115	21	nucleolus	nucleolus	NN
cord-321013-8pkrg0mx	115	22	[	[	-LRB-
cord-321013-8pkrg0mx	115	23	67	67	CD
cord-321013-8pkrg0mx	115	24	]	]	-RRB-
cord-321013-8pkrg0mx	115	25	.	.	.
cord-321013-8pkrg0mx	116	1	Proteins	protein	NNS
cord-321013-8pkrg0mx	116	2	that	that	WDT
cord-321013-8pkrg0mx	116	3	are	be	VBP
cord-321013-8pkrg0mx	116	4	able	able	JJ
cord-321013-8pkrg0mx	116	5	to	to	TO
cord-321013-8pkrg0mx	116	6	localize	localize	VB
cord-321013-8pkrg0mx	116	7	to	to	IN
cord-321013-8pkrg0mx	116	8	the	the	DT
cord-321013-8pkrg0mx	116	9	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	116	10	,	,	,
cord-321013-8pkrg0mx	116	11	nucleus	nucleus	NN
cord-321013-8pkrg0mx	116	12	and/or	and/or	CC
cord-321013-8pkrg0mx	116	13	nucleolus	nucleolus	NN
cord-321013-8pkrg0mx	116	14	require	require	VBP
cord-321013-8pkrg0mx	116	15	multiple	multiple	JJ
cord-321013-8pkrg0mx	116	16	signals	signal	NNS
cord-321013-8pkrg0mx	116	17	to	to	TO
cord-321013-8pkrg0mx	116	18	determine	determine	VB
cord-321013-8pkrg0mx	116	19	their	-PRON-	PRP$
cord-321013-8pkrg0mx	116	20	subcellular	subcellular	JJ
cord-321013-8pkrg0mx	116	21	localization	localization	NN
cord-321013-8pkrg0mx	116	22	[	[	-LRB-
cord-321013-8pkrg0mx	116	23	68	68	CD
cord-321013-8pkrg0mx	116	24	]	]	-RRB-
cord-321013-8pkrg0mx	116	25	.	.	.
cord-321013-8pkrg0mx	117	1	CoV	CoV	NNP
cord-321013-8pkrg0mx	117	2	N	n	CD
cord-321013-8pkrg0mx	117	3	proteins	protein	NNS
cord-321013-8pkrg0mx	117	4	commonly	commonly	RB
cord-321013-8pkrg0mx	117	5	localize	localize	VBP
cord-321013-8pkrg0mx	117	6	in	in	IN
cord-321013-8pkrg0mx	117	7	the	the	DT
cord-321013-8pkrg0mx	117	8	nucleolus	nucleolus	NN
cord-321013-8pkrg0mx	117	9	,	,	,
cord-321013-8pkrg0mx	117	10	and	and	CC
cord-321013-8pkrg0mx	117	11	although	although	IN
cord-321013-8pkrg0mx	117	12	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	117	13	localization	localization	NN
cord-321013-8pkrg0mx	117	14	/	/	SYM
cord-321013-8pkrg0mx	117	15	retention	retention	NN
cord-321013-8pkrg0mx	117	16	signals	signal	NNS
cord-321013-8pkrg0mx	117	17	(	(	-LRB-
cord-321013-8pkrg0mx	117	18	NoRSs	NoRSs	NNP
cord-321013-8pkrg0mx	117	19	)	)	-RRB-
cord-321013-8pkrg0mx	117	20	and	and	CC
cord-321013-8pkrg0mx	117	21	pathways	pathway	NNS
cord-321013-8pkrg0mx	117	22	are	be	VBP
cord-321013-8pkrg0mx	117	23	not	not	RB
cord-321013-8pkrg0mx	117	24	well	well	RB
cord-321013-8pkrg0mx	117	25	characterized	characterize	VBN
cord-321013-8pkrg0mx	117	26	,	,	,
cord-321013-8pkrg0mx	117	27	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	117	28	localization	localization	NN
cord-321013-8pkrg0mx	117	29	usually	usually	RB
cord-321013-8pkrg0mx	117	30	requires	require	VBZ
cord-321013-8pkrg0mx	117	31	regions	region	NNS
cord-321013-8pkrg0mx	117	32	in	in	IN
cord-321013-8pkrg0mx	117	33	the	the	DT
cord-321013-8pkrg0mx	117	34	protein	protein	NN
cord-321013-8pkrg0mx	117	35	that	that	WDT
cord-321013-8pkrg0mx	117	36	are	be	VBP
cord-321013-8pkrg0mx	117	37	rich	rich	JJ
cord-321013-8pkrg0mx	117	38	in	in	IN
cord-321013-8pkrg0mx	117	39	Arg	arg	NN
cord-321013-8pkrg0mx	117	40	residues	residue	NNS
cord-321013-8pkrg0mx	117	41	and	and	CC
cord-321013-8pkrg0mx	117	42	is	be	VBZ
cord-321013-8pkrg0mx	117	43	likely	likely	JJ
cord-321013-8pkrg0mx	117	44	cell	cell	NN
cord-321013-8pkrg0mx	117	45	-	-	HYPH
cord-321013-8pkrg0mx	117	46	cycle	cycle	NN
cord-321013-8pkrg0mx	117	47	dependent	dependent	JJ
cord-321013-8pkrg0mx	117	48	[	[	-LRB-
cord-321013-8pkrg0mx	117	49	34	34	CD
cord-321013-8pkrg0mx	117	50	,	,	,
cord-321013-8pkrg0mx	117	51	69	69	CD
cord-321013-8pkrg0mx	117	52	,	,	,
cord-321013-8pkrg0mx	117	53	70	70	CD
cord-321013-8pkrg0mx	117	54	]	]	-RRB-
cord-321013-8pkrg0mx	117	55	.	.	.
cord-321013-8pkrg0mx	118	1	The	the	DT
cord-321013-8pkrg0mx	118	2	N	n	CD
cord-321013-8pkrg0mx	118	3	protein	protein	NN
cord-321013-8pkrg0mx	118	4	of	of	IN
cord-321013-8pkrg0mx	118	5	IBV	IBV	NNP
cord-321013-8pkrg0mx	118	6	was	be	VBD
cord-321013-8pkrg0mx	118	7	found	find	VBN
cord-321013-8pkrg0mx	118	8	to	to	TO
cord-321013-8pkrg0mx	118	9	localize	localize	VB
cord-321013-8pkrg0mx	118	10	in	in	IN
cord-321013-8pkrg0mx	118	11	the	the	DT
cord-321013-8pkrg0mx	118	12	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	118	13	alone	alone	RB
cord-321013-8pkrg0mx	118	14	or	or	CC
cord-321013-8pkrg0mx	118	15	to	to	TO
cord-321013-8pkrg0mx	118	16	co	co	VB
cord-321013-8pkrg0mx	118	17	-	-	VB
cord-321013-8pkrg0mx	118	18	localize	localize	VB
cord-321013-8pkrg0mx	118	19	in	in	IN
cord-321013-8pkrg0mx	118	20	both	both	CC
cord-321013-8pkrg0mx	118	21	the	the	DT
cord-321013-8pkrg0mx	118	22	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	118	23	and	and	CC
cord-321013-8pkrg0mx	118	24	nucleolus	nucleolus	NN
cord-321013-8pkrg0mx	118	25	[	[	-LRB-
cord-321013-8pkrg0mx	118	26	67	67	CD
cord-321013-8pkrg0mx	118	27	,	,	,
cord-321013-8pkrg0mx	118	28	68	68	CD
cord-321013-8pkrg0mx	118	29	,	,	,
cord-321013-8pkrg0mx	118	30	70	70	CD
cord-321013-8pkrg0mx	118	31	]	]	-RRB-
cord-321013-8pkrg0mx	118	32	.	.	.
cord-321013-8pkrg0mx	119	1	IBV	IBV	NNP
cord-321013-8pkrg0mx	119	2	N	N	NNP
cord-321013-8pkrg0mx	119	3	protein	protein	NN
cord-321013-8pkrg0mx	119	4	contains	contain	VBZ
cord-321013-8pkrg0mx	119	5	a	a	DT
cord-321013-8pkrg0mx	119	6	functional	functional	JJ
cord-321013-8pkrg0mx	119	7	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	119	8	export	export	NN
cord-321013-8pkrg0mx	119	9	signal	signal	NN
cord-321013-8pkrg0mx	119	10	(	(	-LRB-
cord-321013-8pkrg0mx	119	11	NES	NES	NNP
cord-321013-8pkrg0mx	119	12	)	)	-RRB-
cord-321013-8pkrg0mx	119	13	to	to	IN
cord-321013-8pkrg0mx	119	14	traffic	traffic	NN
cord-321013-8pkrg0mx	119	15	N	n	CD
cord-321013-8pkrg0mx	119	16	protein	protein	NN
cord-321013-8pkrg0mx	119	17	to	to	IN
cord-321013-8pkrg0mx	119	18	the	the	DT
cord-321013-8pkrg0mx	119	19	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	119	20	[	[	-LRB-
cord-321013-8pkrg0mx	119	21	68	68	CD
cord-321013-8pkrg0mx	119	22	,	,	,
cord-321013-8pkrg0mx	119	23	71	71	CD
cord-321013-8pkrg0mx	119	24	]	]	-RRB-
cord-321013-8pkrg0mx	119	25	,	,	,
cord-321013-8pkrg0mx	119	26	and	and	CC
cord-321013-8pkrg0mx	119	27	an	an	DT
cord-321013-8pkrg0mx	119	28	8	8	CD
cord-321013-8pkrg0mx	119	29	amino	amino	NN
cord-321013-8pkrg0mx	119	30	acid	acid	NN
cord-321013-8pkrg0mx	119	31	NoRS	NoRS	NNP
cord-321013-8pkrg0mx	119	32	motif	motif	NN
cord-321013-8pkrg0mx	119	33	at	at	IN
cord-321013-8pkrg0mx	119	34	its	-PRON-	PRP$
cord-321013-8pkrg0mx	119	35	NTD	NTD	NNP
cord-321013-8pkrg0mx	119	36	and	and	CC
cord-321013-8pkrg0mx	119	37	is	be	VBZ
cord-321013-8pkrg0mx	119	38	necessary	necessary	JJ
cord-321013-8pkrg0mx	119	39	and	and	CC
cord-321013-8pkrg0mx	119	40	sufficient	sufficient	JJ
cord-321013-8pkrg0mx	119	41	for	for	IN
cord-321013-8pkrg0mx	119	42	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	119	43	retention	retention	NNP
cord-321013-8pkrg0mx	119	44	[	[	-LRB-
cord-321013-8pkrg0mx	119	45	68	68	CD
cord-321013-8pkrg0mx	119	46	]	]	-RRB-
cord-321013-8pkrg0mx	119	47	.	.	.
cord-321013-8pkrg0mx	120	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	120	2	is	be	VBZ
cord-321013-8pkrg0mx	120	3	hypothesized	hypothesize	VBN
cord-321013-8pkrg0mx	120	4	that	that	IN
cord-321013-8pkrg0mx	120	5	the	the	DT
cord-321013-8pkrg0mx	120	6	localization	localization	NN
cord-321013-8pkrg0mx	120	7	of	of	IN
cord-321013-8pkrg0mx	120	8	IBV	IBV	NNP
cord-321013-8pkrg0mx	120	9	-	-	HYPH
cord-321013-8pkrg0mx	120	10	N	N	NNP
cord-321013-8pkrg0mx	120	11	to	to	IN
cord-321013-8pkrg0mx	120	12	the	the	DT
cord-321013-8pkrg0mx	120	13	nucleolus	nucleolus	NN
cord-321013-8pkrg0mx	120	14	forms	form	VBZ
cord-321013-8pkrg0mx	120	15	part	part	NN
cord-321013-8pkrg0mx	120	16	of	of	IN
cord-321013-8pkrg0mx	120	17	a	a	DT
cord-321013-8pkrg0mx	120	18	virus	virus	NN
cord-321013-8pkrg0mx	120	19	strategy	strategy	NN
cord-321013-8pkrg0mx	120	20	to	to	TO
cord-321013-8pkrg0mx	120	21	control	control	VB
cord-321013-8pkrg0mx	120	22	sgRNA	sgRNA	JJR
cord-321013-8pkrg0mx	120	23	synthesis	synthesis	NN
cord-321013-8pkrg0mx	120	24	in	in	IN
cord-321013-8pkrg0mx	120	25	both	both	CC
cord-321013-8pkrg0mx	120	26	the	the	DT
cord-321013-8pkrg0mx	120	27	host	host	NN
cord-321013-8pkrg0mx	120	28	cell	cell	NN
cord-321013-8pkrg0mx	120	29	and	and	CC
cord-321013-8pkrg0mx	120	30	virus	virus	NN
cord-321013-8pkrg0mx	120	31	by	by	IN
cord-321013-8pkrg0mx	120	32	associating	associate	VBG
cord-321013-8pkrg0mx	120	33	with	with	IN
cord-321013-8pkrg0mx	120	34	ribosomal	ribosomal	JJ
cord-321013-8pkrg0mx	120	35	subunits	subunit	NNS
cord-321013-8pkrg0mx	120	36	[	[	-LRB-
cord-321013-8pkrg0mx	120	37	70	70	CD
cord-321013-8pkrg0mx	120	38	]	]	-RRB-
cord-321013-8pkrg0mx	120	39	and	and	CC
cord-321013-8pkrg0mx	120	40	interacting	interact	VBG
cord-321013-8pkrg0mx	120	41	with	with	IN
cord-321013-8pkrg0mx	120	42	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	120	43	proteins	protein	NNS
cord-321013-8pkrg0mx	120	44	,	,	,
cord-321013-8pkrg0mx	120	45	nucleolin	nucleolin	NNP
cord-321013-8pkrg0mx	120	46	and	and	CC
cord-321013-8pkrg0mx	120	47	fibrillarin	fibrillarin	NNP
cord-321013-8pkrg0mx	120	48	[	[	-LRB-
cord-321013-8pkrg0mx	120	49	72	72	CD
cord-321013-8pkrg0mx	120	50	]	]	-RRB-
cord-321013-8pkrg0mx	120	51	.	.	.
cord-321013-8pkrg0mx	121	1	Importantly	importantly	RB
cord-321013-8pkrg0mx	121	2	,	,	,
cord-321013-8pkrg0mx	121	3	this	this	DT
cord-321013-8pkrg0mx	121	4	interaction	interaction	NN
cord-321013-8pkrg0mx	121	5	is	be	VBZ
cord-321013-8pkrg0mx	121	6	not	not	RB
cord-321013-8pkrg0mx	121	7	direct	direct	JJ
cord-321013-8pkrg0mx	121	8	,	,	,
cord-321013-8pkrg0mx	121	9	but	but	CC
cord-321013-8pkrg0mx	121	10	mediated	mediate	VBN
cord-321013-8pkrg0mx	121	11	through	through	IN
cord-321013-8pkrg0mx	121	12	RNA	RNA	NNP
cord-321013-8pkrg0mx	121	13	and	and	CC
cord-321013-8pkrg0mx	121	14	could	could	MD
cord-321013-8pkrg0mx	121	15	therefore	therefore	RB
cord-321013-8pkrg0mx	121	16	simply	simply	RB
cord-321013-8pkrg0mx	121	17	be	be	VB
cord-321013-8pkrg0mx	121	18	an	an	DT
cord-321013-8pkrg0mx	121	19	artifact	artifact	NN
cord-321013-8pkrg0mx	121	20	of	of	IN
cord-321013-8pkrg0mx	121	21	the	the	DT
cord-321013-8pkrg0mx	121	22	proteins	protein	NNS
cord-321013-8pkrg0mx	121	23	having	have	VBG
cord-321013-8pkrg0mx	121	24	RNA	rna	NN
cord-321013-8pkrg0mx	121	25	-	-	HYPH
cord-321013-8pkrg0mx	121	26	binding	bind	VBG
cord-321013-8pkrg0mx	121	27	domains	domain	NNS
cord-321013-8pkrg0mx	121	28	[	[	-LRB-
cord-321013-8pkrg0mx	121	29	73	73	CD
cord-321013-8pkrg0mx	121	30	]	]	-RRB-
cord-321013-8pkrg0mx	121	31	.	.	.
cord-321013-8pkrg0mx	122	1	Thus	thus	RB
cord-321013-8pkrg0mx	122	2	,	,	,
cord-321013-8pkrg0mx	122	3	the	the	DT
cord-321013-8pkrg0mx	122	4	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	122	5	localization	localization	NN
cord-321013-8pkrg0mx	122	6	could	could	MD
cord-321013-8pkrg0mx	122	7	simply	simply	RB
cord-321013-8pkrg0mx	122	8	be	be	VB
cord-321013-8pkrg0mx	122	9	due	due	JJ
cord-321013-8pkrg0mx	122	10	to	to	IN
cord-321013-8pkrg0mx	122	11	a	a	DT
cord-321013-8pkrg0mx	122	12	high	high	JJ
cord-321013-8pkrg0mx	122	13	density	density	NN
cord-321013-8pkrg0mx	122	14	of	of	IN
cord-321013-8pkrg0mx	122	15	the	the	DT
cord-321013-8pkrg0mx	122	16	host	host	NN
cord-321013-8pkrg0mx	122	17	RNA	RNA	NNP
cord-321013-8pkrg0mx	122	18	attracting	attract	VBG
cord-321013-8pkrg0mx	122	19	a	a	DT
cord-321013-8pkrg0mx	122	20	viral	viral	JJ
cord-321013-8pkrg0mx	122	21	RNA	rna	NN
cord-321013-8pkrg0mx	122	22	-	-	HYPH
cord-321013-8pkrg0mx	122	23	binding	bind	VBG
cord-321013-8pkrg0mx	122	24	protein	protein	NN
cord-321013-8pkrg0mx	122	25	.	.	.
cord-321013-8pkrg0mx	123	1	Even	even	RB
cord-321013-8pkrg0mx	123	2	so	so	RB
cord-321013-8pkrg0mx	123	3	,	,	,
cord-321013-8pkrg0mx	123	4	it	-PRON-	PRP
cord-321013-8pkrg0mx	123	5	has	have	VBZ
cord-321013-8pkrg0mx	123	6	been	be	VBN
cord-321013-8pkrg0mx	123	7	postulated	postulate	VBN
cord-321013-8pkrg0mx	123	8	that	that	IN
cord-321013-8pkrg0mx	123	9	the	the	DT
cord-321013-8pkrg0mx	123	10	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	123	11	localization	localization	NN
cord-321013-8pkrg0mx	123	12	of	of	IN
cord-321013-8pkrg0mx	123	13	the	the	DT
cord-321013-8pkrg0mx	123	14	N	N	NNP
cord-321013-8pkrg0mx	123	15	protein	protein	NN
cord-321013-8pkrg0mx	123	16	may	may	MD
cord-321013-8pkrg0mx	123	17	interfere	interfere	VB
cord-321013-8pkrg0mx	123	18	with	with	IN
cord-321013-8pkrg0mx	123	19	cellular	cellular	JJ
cord-321013-8pkrg0mx	123	20	machinery	machinery	NN
cord-321013-8pkrg0mx	123	21	and	and	CC
cord-321013-8pkrg0mx	123	22	thus	thus	RB
cord-321013-8pkrg0mx	123	23	lead	lead	VB
cord-321013-8pkrg0mx	123	24	to	to	IN
cord-321013-8pkrg0mx	123	25	triggering	trigger	VBG
cord-321013-8pkrg0mx	123	26	of	of	IN
cord-321013-8pkrg0mx	123	27	apoptosis	apoptosis	NN
cord-321013-8pkrg0mx	123	28	[	[	-LRB-
cord-321013-8pkrg0mx	123	29	39	39	CD
cord-321013-8pkrg0mx	123	30	]	]	-RRB-
cord-321013-8pkrg0mx	123	31	.	.	.
cord-321013-8pkrg0mx	124	1	The	the	DT
cord-321013-8pkrg0mx	124	2	localization	localization	NN
cord-321013-8pkrg0mx	124	3	of	of	IN
cord-321013-8pkrg0mx	124	4	N	n	CD
cord-321013-8pkrg0mx	124	5	to	to	IN
cord-321013-8pkrg0mx	124	6	nucleoli	nucleoli	NNP
cord-321013-8pkrg0mx	124	7	alone	alone	RB
cord-321013-8pkrg0mx	124	8	might	may	MD
cord-321013-8pkrg0mx	124	9	be	be	VB
cord-321013-8pkrg0mx	124	10	cell	cell	NN
cord-321013-8pkrg0mx	124	11	cycle	cycle	NN
cord-321013-8pkrg0mx	124	12	dependent	dependent	JJ
cord-321013-8pkrg0mx	124	13	,	,	,
cord-321013-8pkrg0mx	124	14	because	because	IN
cord-321013-8pkrg0mx	124	15	the	the	DT
cord-321013-8pkrg0mx	124	16	number	number	NN
cord-321013-8pkrg0mx	124	17	and	and	CC
cord-321013-8pkrg0mx	124	18	size	size	NN
cord-321013-8pkrg0mx	124	19	of	of	IN
cord-321013-8pkrg0mx	124	20	nucleoli	nucleoli	NNP
cord-321013-8pkrg0mx	124	21	differ	differ	VBP
cord-321013-8pkrg0mx	124	22	at	at	IN
cord-321013-8pkrg0mx	124	23	different	different	JJ
cord-321013-8pkrg0mx	124	24	stages	stage	NNS
cord-321013-8pkrg0mx	124	25	of	of	IN
cord-321013-8pkrg0mx	124	26	the	the	DT
cord-321013-8pkrg0mx	124	27	cell	cell	NN
cord-321013-8pkrg0mx	124	28	cycle	cycle	NN
cord-321013-8pkrg0mx	124	29	:	:	:
cord-321013-8pkrg0mx	124	30	at	at	IN
cord-321013-8pkrg0mx	124	31	the	the	DT
cord-321013-8pkrg0mx	124	32	beginning	beginning	NN
cord-321013-8pkrg0mx	124	33	of	of	IN
cord-321013-8pkrg0mx	124	34	G1	G1	NNP
cord-321013-8pkrg0mx	124	35	phase	phase	NN
cord-321013-8pkrg0mx	124	36	,	,	,
cord-321013-8pkrg0mx	124	37	multiple	multiple	JJ
cord-321013-8pkrg0mx	124	38	nucleoli	nucleolus	NNS
cord-321013-8pkrg0mx	124	39	can	can	MD
cord-321013-8pkrg0mx	124	40	be	be	VB
cord-321013-8pkrg0mx	124	41	found	find	VBN
cord-321013-8pkrg0mx	124	42	,	,	,
cord-321013-8pkrg0mx	124	43	but	but	CC
cord-321013-8pkrg0mx	124	44	only	only	RB
cord-321013-8pkrg0mx	124	45	single	single	JJ
cord-321013-8pkrg0mx	124	46	nucleoli	nucleolus	NNS
cord-321013-8pkrg0mx	124	47	can	can	MD
cord-321013-8pkrg0mx	124	48	be	be	VB
cord-321013-8pkrg0mx	124	49	seen	see	VBN
cord-321013-8pkrg0mx	124	50	at	at	IN
cord-321013-8pkrg0mx	124	51	later	later	RB
cord-321013-8pkrg0mx	124	52	G1	G1	NNP
cord-321013-8pkrg0mx	124	53	,	,	,
cord-321013-8pkrg0mx	124	54	S	S	NNP
cord-321013-8pkrg0mx	124	55	and	and	CC
cord-321013-8pkrg0mx	124	56	G2	G2	NNP
cord-321013-8pkrg0mx	124	57	phases	phase	NNS
cord-321013-8pkrg0mx	124	58	[	[	-LRB-
cord-321013-8pkrg0mx	124	59	67	67	CD
cord-321013-8pkrg0mx	124	60	,	,	,
cord-321013-8pkrg0mx	124	61	74	74	CD
cord-321013-8pkrg0mx	124	62	]	]	-RRB-
cord-321013-8pkrg0mx	124	63	.	.	.
cord-321013-8pkrg0mx	125	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	125	2	was	be	VBD
cord-321013-8pkrg0mx	125	3	also	also	RB
cord-321013-8pkrg0mx	125	4	found	find	VBN
cord-321013-8pkrg0mx	125	5	that	that	IN
cord-321013-8pkrg0mx	125	6	domain	domain	NN
cord-321013-8pkrg0mx	125	7	2	2	CD
cord-321013-8pkrg0mx	125	8	of	of	IN
cord-321013-8pkrg0mx	125	9	IBV	IBV	NNP
cord-321013-8pkrg0mx	125	10	-	-	HYPH
cord-321013-8pkrg0mx	125	11	N	N	NNP
cord-321013-8pkrg0mx	125	12	predominantly	predominantly	RB
cord-321013-8pkrg0mx	125	13	localizes	localize	VBZ
cord-321013-8pkrg0mx	125	14	in	in	IN
cord-321013-8pkrg0mx	125	15	the	the	DT
cord-321013-8pkrg0mx	125	16	nucleus	nucleus	NN
cord-321013-8pkrg0mx	125	17	,	,	,
cord-321013-8pkrg0mx	125	18	but	but	CC
cord-321013-8pkrg0mx	125	19	when	when	WRB
cord-321013-8pkrg0mx	125	20	fused	fuse	VBN
cord-321013-8pkrg0mx	125	21	with	with	IN
cord-321013-8pkrg0mx	125	22	domain	domain	NN
cord-321013-8pkrg0mx	125	23	3	3	CD
cord-321013-8pkrg0mx	125	24	(	(	-LRB-
cord-321013-8pkrg0mx	125	25	CTD	CTD	NNP
cord-321013-8pkrg0mx	125	26	)	)	-RRB-
cord-321013-8pkrg0mx	126	1	it	-PRON-	PRP
cord-321013-8pkrg0mx	126	2	localizes	localize	VBZ
cord-321013-8pkrg0mx	126	3	to	to	IN
cord-321013-8pkrg0mx	126	4	the	the	DT
cord-321013-8pkrg0mx	126	5	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	126	6	and	and	CC
cord-321013-8pkrg0mx	126	7	thus	thus	RB
cord-321013-8pkrg0mx	126	8	supports	support	VBZ
cord-321013-8pkrg0mx	126	9	the	the	DT
cord-321013-8pkrg0mx	126	10	findings	finding	NNS
cord-321013-8pkrg0mx	126	11	of	of	IN
cord-321013-8pkrg0mx	126	12	other	other	JJ
cord-321013-8pkrg0mx	126	13	studies	study	NNS
cord-321013-8pkrg0mx	126	14	done	do	VBN
cord-321013-8pkrg0mx	126	15	on	on	IN
cord-321013-8pkrg0mx	126	16	IBV	IBV	NNP
cord-321013-8pkrg0mx	126	17	-	-	HYPH
cord-321013-8pkrg0mx	126	18	N	n	CD
cord-321013-8pkrg0mx	126	19	localization	localization	NN
cord-321013-8pkrg0mx	126	20	[	[	-LRB-
cord-321013-8pkrg0mx	126	21	35	35	CD
cord-321013-8pkrg0mx	126	22	,	,	,
cord-321013-8pkrg0mx	126	23	68	68	CD
cord-321013-8pkrg0mx	126	24	]	]	-RRB-
cord-321013-8pkrg0mx	126	25	.	.	.
cord-321013-8pkrg0mx	127	1	The	the	DT
cord-321013-8pkrg0mx	127	2	ability	ability	NN
cord-321013-8pkrg0mx	127	3	for	for	IN
cord-321013-8pkrg0mx	127	4	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	127	5	localization	localization	NN
cord-321013-8pkrg0mx	127	6	varies	vary	VBZ
cord-321013-8pkrg0mx	127	7	between	between	IN
cord-321013-8pkrg0mx	127	8	N	n	CD
cord-321013-8pkrg0mx	127	9	proteins	protein	NNS
cord-321013-8pkrg0mx	127	10	of	of	IN
cord-321013-8pkrg0mx	127	11	different	different	JJ
cord-321013-8pkrg0mx	127	12	CoVs	covs	NN
cord-321013-8pkrg0mx	127	13	.	.	.
cord-321013-8pkrg0mx	128	1	Unlike	unlike	IN
cord-321013-8pkrg0mx	128	2	other	other	JJ
cord-321013-8pkrg0mx	128	3	CoV	cov	NN
cord-321013-8pkrg0mx	128	4	N	n	CD
cord-321013-8pkrg0mx	128	5	proteins	protein	NNS
cord-321013-8pkrg0mx	128	6	,	,	,
cord-321013-8pkrg0mx	128	7	SARS	SARS	NNP
cord-321013-8pkrg0mx	128	8	-	-	HYPH
cord-321013-8pkrg0mx	128	9	CoV	CoV	NNP
cord-321013-8pkrg0mx	128	10	N	n	CD
cord-321013-8pkrg0mx	128	11	protein	protein	NN
cord-321013-8pkrg0mx	128	12	is	be	VBZ
cord-321013-8pkrg0mx	128	13	mostly	mostly	RB
cord-321013-8pkrg0mx	128	14	distributed	distribute	VBN
cord-321013-8pkrg0mx	128	15	to	to	IN
cord-321013-8pkrg0mx	128	16	the	the	DT
cord-321013-8pkrg0mx	128	17	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	128	18	[	[	-LRB-
cord-321013-8pkrg0mx	128	19	34	34	CD
cord-321013-8pkrg0mx	128	20	,	,	,
cord-321013-8pkrg0mx	128	21	71	71	CD
cord-321013-8pkrg0mx	128	22	,	,	,
cord-321013-8pkrg0mx	128	23	75	75	CD
cord-321013-8pkrg0mx	128	24	]	]	-RRB-
cord-321013-8pkrg0mx	128	25	.	.	.
cord-321013-8pkrg0mx	129	1	This	this	DT
cord-321013-8pkrg0mx	129	2	cytoplasmic	cytoplasmic	JJ
cord-321013-8pkrg0mx	129	3	localization	localization	NN
cord-321013-8pkrg0mx	129	4	is	be	VBZ
cord-321013-8pkrg0mx	129	5	somewhat	somewhat	RB
cord-321013-8pkrg0mx	129	6	unexpected	unexpected	JJ
cord-321013-8pkrg0mx	129	7	because	because	IN
cord-321013-8pkrg0mx	129	8	there	there	EX
cord-321013-8pkrg0mx	129	9	is	be	VBZ
cord-321013-8pkrg0mx	129	10	at	at	RB
cord-321013-8pkrg0mx	129	11	least	least	RBS
cord-321013-8pkrg0mx	129	12	one	one	CD
cord-321013-8pkrg0mx	129	13	NoRS	NoRS	NNP
cord-321013-8pkrg0mx	129	14	in	in	IN
cord-321013-8pkrg0mx	129	15	domain	domain	NN
cord-321013-8pkrg0mx	129	16	2	2	CD
cord-321013-8pkrg0mx	129	17	and	and	CC
cord-321013-8pkrg0mx	129	18	eight	eight	CD
cord-321013-8pkrg0mx	129	19	putative	putative	JJ
cord-321013-8pkrg0mx	129	20	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	129	21	localization	localization	NN
cord-321013-8pkrg0mx	129	22	signal	signal	NN
cord-321013-8pkrg0mx	129	23	(	(	-LRB-
cord-321013-8pkrg0mx	129	24	NLS	NLS	NNP
cord-321013-8pkrg0mx	129	25	)	)	-RRB-
cord-321013-8pkrg0mx	129	26	motifs	motif	NNS
cord-321013-8pkrg0mx	129	27	within	within	IN
cord-321013-8pkrg0mx	129	28	domains	domain	NNS
cord-321013-8pkrg0mx	130	1	I	-PRON-	PRP
cord-321013-8pkrg0mx	130	2	and	and	CC
cord-321013-8pkrg0mx	130	3	II	II	NNP
cord-321013-8pkrg0mx	130	4	of	of	IN
cord-321013-8pkrg0mx	130	5	the	the	DT
cord-321013-8pkrg0mx	130	6	SARS	SARS	NNP
cord-321013-8pkrg0mx	130	7	-	-	HYPH
cord-321013-8pkrg0mx	130	8	CoV	CoV	NNP
cord-321013-8pkrg0mx	130	9	N	n	CD
cord-321013-8pkrg0mx	130	10	protein	protein	NN
cord-321013-8pkrg0mx	130	11	[	[	-LRB-
cord-321013-8pkrg0mx	130	12	35	35	CD
cord-321013-8pkrg0mx	130	13	]	]	-RRB-
cord-321013-8pkrg0mx	130	14	,	,	,
cord-321013-8pkrg0mx	130	15	of	of	IN
cord-321013-8pkrg0mx	130	16	which	which	WDT
cord-321013-8pkrg0mx	130	17	the	the	DT
cord-321013-8pkrg0mx	130	18	short	short	JJ
cord-321013-8pkrg0mx	130	19	lysine	lysine	NN
cord-321013-8pkrg0mx	130	20	-	-	HYPH
cord-321013-8pkrg0mx	130	21	rich	rich	JJ
cord-321013-8pkrg0mx	130	22	sequence	sequence	NN
cord-321013-8pkrg0mx	130	23	(	(	-LRB-
cord-321013-8pkrg0mx	130	24	366	366	CD
cord-321013-8pkrg0mx	130	25	-	-	SYM
cord-321013-8pkrg0mx	130	26	381	381	CD
cord-321013-8pkrg0mx	130	27	)	)	-RRB-
cord-321013-8pkrg0mx	130	28	near	near	IN
cord-321013-8pkrg0mx	130	29	the	the	DT
cord-321013-8pkrg0mx	130	30	carboxy	carboxy	JJ
cord-321013-8pkrg0mx	130	31	-	-	HYPH
cord-321013-8pkrg0mx	130	32	terminus	terminus	NN
cord-321013-8pkrg0mx	130	33	is	be	VBZ
cord-321013-8pkrg0mx	130	34	a	a	DT
cord-321013-8pkrg0mx	130	35	putative	putative	JJ
cord-321013-8pkrg0mx	130	36	bipartite	bipartite	JJ
cord-321013-8pkrg0mx	130	37	NLS	nls	NN
cord-321013-8pkrg0mx	130	38	that	that	WDT
cord-321013-8pkrg0mx	130	39	is	be	VBZ
cord-321013-8pkrg0mx	130	40	unique	unique	JJ
cord-321013-8pkrg0mx	130	41	to	to	IN
cord-321013-8pkrg0mx	130	42	SARS	SARS	NNP
cord-321013-8pkrg0mx	130	43	-	-	HYPH
cord-321013-8pkrg0mx	130	44	CoV	CoV	NNP
cord-321013-8pkrg0mx	130	45	N	N	NNP
cord-321013-8pkrg0mx	130	46	[	[	-LRB-
cord-321013-8pkrg0mx	130	47	71	71	CD
cord-321013-8pkrg0mx	130	48	,	,	,
cord-321013-8pkrg0mx	130	49	76	76	CD
cord-321013-8pkrg0mx	130	50	]	]	-RRB-
cord-321013-8pkrg0mx	130	51	.	.	.
cord-321013-8pkrg0mx	131	1	As	as	IN
cord-321013-8pkrg0mx	131	2	a	a	DT
cord-321013-8pkrg0mx	131	3	reason	reason	NN
cord-321013-8pkrg0mx	131	4	for	for	IN
cord-321013-8pkrg0mx	131	5	this	this	DT
cord-321013-8pkrg0mx	131	6	,	,	,
cord-321013-8pkrg0mx	131	7	it	-PRON-	PRP
cord-321013-8pkrg0mx	131	8	has	have	VBZ
cord-321013-8pkrg0mx	131	9	been	be	VBN
cord-321013-8pkrg0mx	131	10	suggested	suggest	VBN
cord-321013-8pkrg0mx	131	11	that	that	IN
cord-321013-8pkrg0mx	131	12	signals	signal	NNS
cord-321013-8pkrg0mx	131	13	for	for	IN
cord-321013-8pkrg0mx	131	14	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	131	15	and	and	CC
cord-321013-8pkrg0mx	131	16	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	131	17	targeting	target	VBG
cord-321013-8pkrg0mx	131	18	of	of	IN
cord-321013-8pkrg0mx	131	19	SARS	SARS	NNP
cord-321013-8pkrg0mx	131	20	-	-	HYPH
cord-321013-8pkrg0mx	131	21	CoV	CoV	NNP
cord-321013-8pkrg0mx	131	22	N	n	CD
cord-321013-8pkrg0mx	131	23	protein	protein	NN
cord-321013-8pkrg0mx	131	24	are	be	VBP
cord-321013-8pkrg0mx	131	25	poorly	poorly	RB
cord-321013-8pkrg0mx	131	26	accessible	accessible	JJ
cord-321013-8pkrg0mx	131	27	to	to	IN
cord-321013-8pkrg0mx	131	28	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	131	29	import	import	NN
cord-321013-8pkrg0mx	131	30	machinery	machinery	NN
cord-321013-8pkrg0mx	131	31	due	due	IN
cord-321013-8pkrg0mx	131	32	to	to	IN
cord-321013-8pkrg0mx	131	33	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	131	34	or	or	CC
cord-321013-8pkrg0mx	131	35	conformation	conformation	NN
cord-321013-8pkrg0mx	131	36	restraints	restraint	NNS
cord-321013-8pkrg0mx	131	37	[	[	-LRB-
cord-321013-8pkrg0mx	131	38	71	71	CD
cord-321013-8pkrg0mx	131	39	]	]	-RRB-
cord-321013-8pkrg0mx	131	40	.	.	.
cord-321013-8pkrg0mx	132	1	A	a	DT
cord-321013-8pkrg0mx	132	2	cytoplasmic	cytoplasmic	JJ
cord-321013-8pkrg0mx	132	3	NES	NES	NNP
cord-321013-8pkrg0mx	132	4	may	may	MD
cord-321013-8pkrg0mx	132	5	be	be	VB
cord-321013-8pkrg0mx	132	6	involved	involve	VBN
cord-321013-8pkrg0mx	132	7	in	in	IN
cord-321013-8pkrg0mx	132	8	also	also	RB
cord-321013-8pkrg0mx	132	9	over	over	RB
cord-321013-8pkrg0mx	132	10	-	-	HYPH
cord-321013-8pkrg0mx	132	11	riding	ride	VBG
cord-321013-8pkrg0mx	132	12	the	the	DT
cord-321013-8pkrg0mx	132	13	NLS	nls	NN
cord-321013-8pkrg0mx	132	14	,	,	,
cord-321013-8pkrg0mx	132	15	resulting	result	VBG
cord-321013-8pkrg0mx	132	16	in	in	IN
cord-321013-8pkrg0mx	132	17	significantly	significantly	RB
cord-321013-8pkrg0mx	132	18	less	less	JJR
cord-321013-8pkrg0mx	132	19	N	n	CD
cord-321013-8pkrg0mx	132	20	protein	protein	NN
cord-321013-8pkrg0mx	132	21	(	(	-LRB-
cord-321013-8pkrg0mx	132	22	only	only	RB
cord-321013-8pkrg0mx	132	23	10	10	CD
cord-321013-8pkrg0mx	132	24	%	%	NN
cord-321013-8pkrg0mx	132	25	)	)	-RRB-
cord-321013-8pkrg0mx	132	26	being	be	VBG
cord-321013-8pkrg0mx	132	27	localized	localize	VBN
cord-321013-8pkrg0mx	132	28	to	to	IN
cord-321013-8pkrg0mx	132	29	the	the	DT
cord-321013-8pkrg0mx	132	30	nucleolus	nucleolus	NN
cord-321013-8pkrg0mx	132	31	[	[	-LRB-
cord-321013-8pkrg0mx	132	32	35	35	CD
cord-321013-8pkrg0mx	132	33	]	]	-RRB-
cord-321013-8pkrg0mx	132	34	.	.	.
cord-321013-8pkrg0mx	133	1	Shuttling	shuttle	VBG
cord-321013-8pkrg0mx	133	2	of	of	IN
cord-321013-8pkrg0mx	133	3	N	n	CD
cord-321013-8pkrg0mx	133	4	protein	protein	NN
cord-321013-8pkrg0mx	133	5	from	from	IN
cord-321013-8pkrg0mx	133	6	the	the	DT
cord-321013-8pkrg0mx	133	7	nucleus	nucleus	NN
cord-321013-8pkrg0mx	133	8	to	to	IN
cord-321013-8pkrg0mx	133	9	the	the	DT
cord-321013-8pkrg0mx	133	10	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	133	11	occurs	occur	VBZ
cord-321013-8pkrg0mx	133	12	through	through	IN
cord-321013-8pkrg0mx	133	13	phosphorylated	phosphorylate	VBN
cord-321013-8pkrg0mx	133	14	-	-	HYPH
cord-321013-8pkrg0mx	133	15	dependent	dependent	JJ
cord-321013-8pkrg0mx	133	16	binding	binding	NN
cord-321013-8pkrg0mx	133	17	of	of	IN
cord-321013-8pkrg0mx	133	18	SARS	SARS	NNP
cord-321013-8pkrg0mx	133	19	-	-	HYPH
cord-321013-8pkrg0mx	133	20	CoV	CoV	NNP
cord-321013-8pkrg0mx	133	21	to	to	IN
cord-321013-8pkrg0mx	133	22	14	14	CD
cord-321013-8pkrg0mx	133	23	-	-	SYM
cord-321013-8pkrg0mx	133	24	3	3	CD
cord-321013-8pkrg0mx	133	25	-	-	SYM
cord-321013-8pkrg0mx	133	26	3	3	CD
cord-321013-8pkrg0mx	133	27	,	,	,
cord-321013-8pkrg0mx	133	28	with	with	IN
cord-321013-8pkrg0mx	133	29	the	the	DT
cord-321013-8pkrg0mx	133	30	absence	absence	NN
cord-321013-8pkrg0mx	133	31	/	/	SYM
cord-321013-8pkrg0mx	133	32	inhibition	inhibition	NN
cord-321013-8pkrg0mx	133	33	of	of	IN
cord-321013-8pkrg0mx	133	34	this	this	DT
cord-321013-8pkrg0mx	133	35	14	14	CD
cord-321013-8pkrg0mx	133	36	-	-	SYM
cord-321013-8pkrg0mx	133	37	3	3	CD
cord-321013-8pkrg0mx	133	38	-	-	SYM
cord-321013-8pkrg0mx	133	39	3	3	CD
cord-321013-8pkrg0mx	133	40	molecule	molecule	NN
cord-321013-8pkrg0mx	133	41	resulting	result	VBG
cord-321013-8pkrg0mx	133	42	in	in	IN
cord-321013-8pkrg0mx	133	43	increased	increase	VBN
cord-321013-8pkrg0mx	133	44	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	133	45	localization	localization	NN
cord-321013-8pkrg0mx	133	46	of	of	IN
cord-321013-8pkrg0mx	133	47	SARS	SARS	NNP
cord-321013-8pkrg0mx	133	48	-	-	HYPH
cord-321013-8pkrg0mx	133	49	N	N	NNP
cord-321013-8pkrg0mx	133	50	[	[	-LRB-
cord-321013-8pkrg0mx	133	51	38	38	CD
cord-321013-8pkrg0mx	133	52	]	]	-RRB-
cord-321013-8pkrg0mx	133	53	.	.	.
cord-321013-8pkrg0mx	134	1	Also	also	RB
cord-321013-8pkrg0mx	134	2	,	,	,
cord-321013-8pkrg0mx	134	3	the	the	DT
cord-321013-8pkrg0mx	134	4	deletion	deletion	NN
cord-321013-8pkrg0mx	134	5	of	of	IN
cord-321013-8pkrg0mx	134	6	the	the	DT
cord-321013-8pkrg0mx	134	7	SR	SR	NNP
cord-321013-8pkrg0mx	134	8	-	-	HYPH
cord-321013-8pkrg0mx	134	9	rich	rich	JJ
cord-321013-8pkrg0mx	134	10	domain	domain	NN
cord-321013-8pkrg0mx	134	11	contained	contain	VBN
cord-321013-8pkrg0mx	134	12	within	within	IN
cord-321013-8pkrg0mx	134	13	the	the	DT
cord-321013-8pkrg0mx	134	14	middle	middle	JJ
cord-321013-8pkrg0mx	134	15	region	region	NN
cord-321013-8pkrg0mx	134	16	of	of	IN
cord-321013-8pkrg0mx	134	17	SARS	SARS	NNP
cord-321013-8pkrg0mx	134	18	-	-	HYPH
cord-321013-8pkrg0mx	134	19	N	N	NNP
cord-321013-8pkrg0mx	134	20	can	can	MD
cord-321013-8pkrg0mx	134	21	result	result	VB
cord-321013-8pkrg0mx	134	22	in	in	IN
cord-321013-8pkrg0mx	134	23	dramatic	dramatic	JJ
cord-321013-8pkrg0mx	134	24	changes	change	NNS
cord-321013-8pkrg0mx	134	25	in	in	IN
cord-321013-8pkrg0mx	134	26	sub	sub	JJ
cord-321013-8pkrg0mx	134	27	-	-	JJ
cord-321013-8pkrg0mx	134	28	cellular	cellular	JJ
cord-321013-8pkrg0mx	134	29	localization	localization	NN
cord-321013-8pkrg0mx	134	30	of	of	IN
cord-321013-8pkrg0mx	134	31	N	n	CD
cord-321013-8pkrg0mx	134	32	compared	compare	VBN
cord-321013-8pkrg0mx	134	33	to	to	IN
cord-321013-8pkrg0mx	134	34	wild	wild	JJ
cord-321013-8pkrg0mx	134	35	-	-	HYPH
cord-321013-8pkrg0mx	134	36	type	type	NN
cord-321013-8pkrg0mx	134	37	N	n	NN
cord-321013-8pkrg0mx	134	38	[	[	-LRB-
cord-321013-8pkrg0mx	134	39	44	44	CD
cord-321013-8pkrg0mx	134	40	]	]	-RRB-
cord-321013-8pkrg0mx	134	41	.	.	.
cord-321013-8pkrg0mx	135	1	These	these	DT
cord-321013-8pkrg0mx	135	2	results	result	NNS
cord-321013-8pkrg0mx	135	3	indicate	indicate	VBP
cord-321013-8pkrg0mx	135	4	that	that	IN
cord-321013-8pkrg0mx	135	5	the	the	DT
cord-321013-8pkrg0mx	135	6	localization	localization	NN
cord-321013-8pkrg0mx	135	7	of	of	IN
cord-321013-8pkrg0mx	135	8	N	n	CD
cord-321013-8pkrg0mx	135	9	protein	protein	NN
cord-321013-8pkrg0mx	135	10	to	to	IN
cord-321013-8pkrg0mx	135	11	the	the	DT
cord-321013-8pkrg0mx	135	12	nucleus	nucleus	NN
cord-321013-8pkrg0mx	135	13	or	or	CC
cord-321013-8pkrg0mx	135	14	nucleolus	nucleolus	NN
cord-321013-8pkrg0mx	135	15	is	be	VBZ
cord-321013-8pkrg0mx	135	16	not	not	RB
cord-321013-8pkrg0mx	135	17	a	a	DT
cord-321013-8pkrg0mx	135	18	conserved	conserved	JJ
cord-321013-8pkrg0mx	135	19	property	property	NN
cord-321013-8pkrg0mx	135	20	of	of	IN
cord-321013-8pkrg0mx	135	21	Nidovirales	Nidovirales	NNP
cord-321013-8pkrg0mx	135	22	[	[	-LRB-
cord-321013-8pkrg0mx	135	23	71	71	CD
cord-321013-8pkrg0mx	135	24	]	]	-RRB-
cord-321013-8pkrg0mx	135	25	.	.	.
cord-321013-8pkrg0mx	136	1	The	the	DT
cord-321013-8pkrg0mx	136	2	primary	primary	JJ
cord-321013-8pkrg0mx	136	3	role	role	NN
cord-321013-8pkrg0mx	136	4	of	of	IN
cord-321013-8pkrg0mx	136	5	CoV	CoV	NNP
cord-321013-8pkrg0mx	136	6	N	n	CD
cord-321013-8pkrg0mx	136	7	protein	protein	NN
cord-321013-8pkrg0mx	136	8	is	be	VBZ
cord-321013-8pkrg0mx	136	9	to	to	TO
cord-321013-8pkrg0mx	136	10	package	package	VB
cord-321013-8pkrg0mx	136	11	the	the	DT
cord-321013-8pkrg0mx	136	12	genomic	genomic	JJ
cord-321013-8pkrg0mx	136	13	viral	viral	JJ
cord-321013-8pkrg0mx	136	14	genome	genome	NN
cord-321013-8pkrg0mx	136	15	into	into	IN
cord-321013-8pkrg0mx	136	16	long	long	JJ
cord-321013-8pkrg0mx	136	17	,	,	,
cord-321013-8pkrg0mx	136	18	flexible	flexible	JJ
cord-321013-8pkrg0mx	136	19	,	,	,
cord-321013-8pkrg0mx	136	20	helical	helical	JJ
cord-321013-8pkrg0mx	136	21	ribonucleoprotein	ribonucleoprotein	NN
cord-321013-8pkrg0mx	136	22	(	(	-LRB-
cord-321013-8pkrg0mx	136	23	RNP	RNP	NNP
cord-321013-8pkrg0mx	136	24	)	)	-RRB-
cord-321013-8pkrg0mx	136	25	complexes	complex	NNS
cord-321013-8pkrg0mx	136	26	called	call	VBD
cord-321013-8pkrg0mx	136	27	nucleocapsids	nucleocapsids	NNP
cord-321013-8pkrg0mx	136	28	or	or	CC
cord-321013-8pkrg0mx	136	29	capsids	capsid	NNS
cord-321013-8pkrg0mx	136	30	(	(	-LRB-
cord-321013-8pkrg0mx	136	31	Table	table	NN
cord-321013-8pkrg0mx	136	32	1	1	CD
cord-321013-8pkrg0mx	136	33	)	)	-RRB-
cord-321013-8pkrg0mx	136	34	.	.	.
cord-321013-8pkrg0mx	137	1	The	the	DT
cord-321013-8pkrg0mx	137	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	137	3	protects	protect	VBZ
cord-321013-8pkrg0mx	137	4	the	the	DT
cord-321013-8pkrg0mx	137	5	genome	genome	NN
cord-321013-8pkrg0mx	137	6	and	and	CC
cord-321013-8pkrg0mx	137	7	ensures	ensure	VBZ
cord-321013-8pkrg0mx	137	8	its	-PRON-	PRP$
cord-321013-8pkrg0mx	137	9	timely	timely	JJ
cord-321013-8pkrg0mx	137	10	replication	replication	NN
cord-321013-8pkrg0mx	137	11	and	and	CC
cord-321013-8pkrg0mx	137	12	reliable	reliable	JJ
cord-321013-8pkrg0mx	137	13	transmission	transmission	NN
cord-321013-8pkrg0mx	137	14	.	.	.
cord-321013-8pkrg0mx	138	1	The	the	DT
cord-321013-8pkrg0mx	138	2	filamentous	filamentous	JJ
cord-321013-8pkrg0mx	138	3	nucleocapsids	nucleocapsid	NNS
cord-321013-8pkrg0mx	138	4	are	be	VBP
cord-321013-8pkrg0mx	138	5	10	10	CD
cord-321013-8pkrg0mx	138	6	to	to	TO
cord-321013-8pkrg0mx	138	7	15	15	CD
cord-321013-8pkrg0mx	138	8	nm	nm	NN
cord-321013-8pkrg0mx	138	9	in	in	IN
cord-321013-8pkrg0mx	138	10	diameter	diameter	NN
cord-321013-8pkrg0mx	138	11	and	and	CC
cord-321013-8pkrg0mx	138	12	several	several	JJ
cord-321013-8pkrg0mx	138	13	100	100	CD
cord-321013-8pkrg0mx	138	14	nm	nm	NN
cord-321013-8pkrg0mx	138	15	in	in	IN
cord-321013-8pkrg0mx	138	16	length	length	NN
cord-321013-8pkrg0mx	138	17	,	,	,
cord-321013-8pkrg0mx	138	18	and	and	CC
cord-321013-8pkrg0mx	138	19	these	these	DT
cord-321013-8pkrg0mx	138	20	macromolecular	macromolecular	JJ
cord-321013-8pkrg0mx	138	21	structures	structure	NNS
cord-321013-8pkrg0mx	138	22	are	be	VBP
cord-321013-8pkrg0mx	138	23	visible	visible	JJ
cord-321013-8pkrg0mx	138	24	using	use	VBG
cord-321013-8pkrg0mx	138	25	electron	electron	NN
cord-321013-8pkrg0mx	138	26	microscopy	microscopy	NNS
cord-321013-8pkrg0mx	138	27	[	[	-LRB-
cord-321013-8pkrg0mx	138	28	77	77	CD
cord-321013-8pkrg0mx	138	29	]	]	-RRB-
cord-321013-8pkrg0mx	138	30	.	.	.
cord-321013-8pkrg0mx	139	1	Within	within	IN
cord-321013-8pkrg0mx	139	2	the	the	DT
cord-321013-8pkrg0mx	139	3	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	139	4	there	there	EX
cord-321013-8pkrg0mx	139	5	are	be	VBP
cord-321013-8pkrg0mx	139	6	both	both	DT
cord-321013-8pkrg0mx	139	7	N	N	NNP
cord-321013-8pkrg0mx	139	8	-	-	HYPH
cord-321013-8pkrg0mx	139	9	RNA	RNA	NNP
cord-321013-8pkrg0mx	139	10	interactions	interaction	NNS
cord-321013-8pkrg0mx	139	11	as	as	RB
cord-321013-8pkrg0mx	139	12	well	well	RB
cord-321013-8pkrg0mx	139	13	as	as	IN
cord-321013-8pkrg0mx	139	14	intermolecular	intermolecular	NNP
cord-321013-8pkrg0mx	139	15	association	association	NNP
cord-321013-8pkrg0mx	139	16	between	between	IN
cord-321013-8pkrg0mx	139	17	disulfide	disulfide	RB
cord-321013-8pkrg0mx	139	18	-	-	HYPH
cord-321013-8pkrg0mx	139	19	linked	link	VBN
cord-321013-8pkrg0mx	139	20	N	n	CD
cord-321013-8pkrg0mx	139	21	protein	protein	NN
cord-321013-8pkrg0mx	139	22	multimers	multimer	NNS
cord-321013-8pkrg0mx	139	23	[	[	-LRB-
cord-321013-8pkrg0mx	139	24	78	78	CD
cord-321013-8pkrg0mx	139	25	]	]	-RRB-
cord-321013-8pkrg0mx	139	26	.	.	.
cord-321013-8pkrg0mx	140	1	The	the	DT
cord-321013-8pkrg0mx	140	2	N	N	NNP
cord-321013-8pkrg0mx	140	3	-	-	HYPH
cord-321013-8pkrg0mx	140	4	RNA	RNA	NNP
cord-321013-8pkrg0mx	140	5	interaction	interaction	NN
cord-321013-8pkrg0mx	140	6	is	be	VBZ
cord-321013-8pkrg0mx	140	7	mediated	mediate	VBN
cord-321013-8pkrg0mx	140	8	by	by	IN
cord-321013-8pkrg0mx	140	9	binding	bind	VBG
cord-321013-8pkrg0mx	140	10	signals	signal	NNS
cord-321013-8pkrg0mx	140	11	contained	contain	VBN
cord-321013-8pkrg0mx	140	12	within	within	IN
cord-321013-8pkrg0mx	140	13	the	the	DT
cord-321013-8pkrg0mx	140	14	leader	leader	NN
cord-321013-8pkrg0mx	140	15	RNA	RNA	NNP
cord-321013-8pkrg0mx	140	16	sequences	sequence	NNS
cord-321013-8pkrg0mx	140	17	[	[	-LRB-
cord-321013-8pkrg0mx	140	18	79	79	CD
cord-321013-8pkrg0mx	140	19	]	]	-RRB-
cord-321013-8pkrg0mx	140	20	.	.	.
cord-321013-8pkrg0mx	141	1	During	during	IN
cord-321013-8pkrg0mx	141	2	the	the	DT
cord-321013-8pkrg0mx	141	3	virus	virus	NN
cord-321013-8pkrg0mx	141	4	life	life	NN
cord-321013-8pkrg0mx	141	5	cycle	cycle	NN
cord-321013-8pkrg0mx	141	6	,	,	,
cord-321013-8pkrg0mx	141	7	multiple	multiple	JJ
cord-321013-8pkrg0mx	141	8	copies	copy	NNS
cord-321013-8pkrg0mx	141	9	of	of	IN
cord-321013-8pkrg0mx	141	10	the	the	DT
cord-321013-8pkrg0mx	141	11	N	N	NNP
cord-321013-8pkrg0mx	141	12	protein	protein	NN
cord-321013-8pkrg0mx	141	13	interact	interact	VBP
cord-321013-8pkrg0mx	141	14	with	with	IN
cord-321013-8pkrg0mx	141	15	gRNA	gRNA	NNS
cord-321013-8pkrg0mx	141	16	and	and	CC
cord-321013-8pkrg0mx	141	17	sgRNA	sgrna	NN
cord-321013-8pkrg0mx	141	18	molecules	molecule	NNS
cord-321013-8pkrg0mx	141	19	,	,	,
cord-321013-8pkrg0mx	141	20	indicating	indicate	VBG
cord-321013-8pkrg0mx	141	21	a	a	DT
cord-321013-8pkrg0mx	141	22	role	role	NN
cord-321013-8pkrg0mx	141	23	for	for	IN
cord-321013-8pkrg0mx	141	24	N	n	CD
cord-321013-8pkrg0mx	141	25	protein	protein	NN
cord-321013-8pkrg0mx	141	26	in	in	IN
cord-321013-8pkrg0mx	141	27	viral	viral	JJ
cord-321013-8pkrg0mx	141	28	transcription	transcription	NN
cord-321013-8pkrg0mx	141	29	and	and	CC
cord-321013-8pkrg0mx	141	30	translation	translation	NN
cord-321013-8pkrg0mx	141	31	[	[	-LRB-
cord-321013-8pkrg0mx	141	32	79	79	CD
cord-321013-8pkrg0mx	141	33	,	,	,
cord-321013-8pkrg0mx	141	34	80	80	CD
cord-321013-8pkrg0mx	141	35	]	]	-RRB-
cord-321013-8pkrg0mx	141	36	.	.	.
cord-321013-8pkrg0mx	142	1	The	the	DT
cord-321013-8pkrg0mx	142	2	basic	basic	JJ
cord-321013-8pkrg0mx	142	3	building	building	NN
cord-321013-8pkrg0mx	142	4	block	block	NN
cord-321013-8pkrg0mx	142	5	for	for	IN
cord-321013-8pkrg0mx	142	6	CoV	CoV	NNP
cord-321013-8pkrg0mx	142	7	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	142	8	formation	formation	NN
cord-321013-8pkrg0mx	142	9	is	be	VBZ
cord-321013-8pkrg0mx	142	10	a	a	DT
cord-321013-8pkrg0mx	142	11	dimeric	dimeric	JJ
cord-321013-8pkrg0mx	142	12	assembly	assembly	NN
cord-321013-8pkrg0mx	142	13	of	of	IN
cord-321013-8pkrg0mx	142	14	N	N	NNP
cord-321013-8pkrg0mx	142	15	protein	protein	NN
cord-321013-8pkrg0mx	142	16	[	[	-LRB-
cord-321013-8pkrg0mx	142	17	21	21	CD
cord-321013-8pkrg0mx	142	18	]	]	-RRB-
cord-321013-8pkrg0mx	142	19	,	,	,
cord-321013-8pkrg0mx	142	20	and	and	CC
cord-321013-8pkrg0mx	142	21	it	-PRON-	PRP
cord-321013-8pkrg0mx	142	22	is	be	VBZ
cord-321013-8pkrg0mx	142	23	the	the	DT
cord-321013-8pkrg0mx	142	24	CTD	CTD	NNP
cord-321013-8pkrg0mx	142	25	of	of	IN
cord-321013-8pkrg0mx	142	26	N	n	CD
cord-321013-8pkrg0mx	142	27	protein	protein	NN
cord-321013-8pkrg0mx	142	28	that	that	WDT
cord-321013-8pkrg0mx	142	29	possesses	possess	VBZ
cord-321013-8pkrg0mx	142	30	dimerization	dimerization	NN
cord-321013-8pkrg0mx	142	31	function	function	NN
cord-321013-8pkrg0mx	142	32	[	[	-LRB-
cord-321013-8pkrg0mx	142	33	56	56	CD
cord-321013-8pkrg0mx	142	34	]	]	-RRB-
cord-321013-8pkrg0mx	142	35	.	.	.
cord-321013-8pkrg0mx	143	1	A	a	DT
cord-321013-8pkrg0mx	143	2	structural	structural	JJ
cord-321013-8pkrg0mx	143	3	model	model	NN
cord-321013-8pkrg0mx	143	4	of	of	IN
cord-321013-8pkrg0mx	143	5	CoV	CoV	NNP
cord-321013-8pkrg0mx	143	6	proposes	propose	VBZ
cord-321013-8pkrg0mx	143	7	that	that	IN
cord-321013-8pkrg0mx	143	8	N	n	CD
cord-321013-8pkrg0mx	143	9	protein	protein	NN
cord-321013-8pkrg0mx	143	10	is	be	VBZ
cord-321013-8pkrg0mx	143	11	not	not	RB
cord-321013-8pkrg0mx	143	12	only	only	RB
cord-321013-8pkrg0mx	143	13	present	present	JJ
cord-321013-8pkrg0mx	143	14	in	in	IN
cord-321013-8pkrg0mx	143	15	the	the	DT
cord-321013-8pkrg0mx	143	16	helical	helical	JJ
cord-321013-8pkrg0mx	143	17	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	143	18	but	but	CC
cord-321013-8pkrg0mx	143	19	also	also	RB
cord-321013-8pkrg0mx	143	20	in	in	IN
cord-321013-8pkrg0mx	143	21	the	the	DT
cord-321013-8pkrg0mx	143	22	internal	internal	JJ
cord-321013-8pkrg0mx	143	23	spherical	spherical	JJ
cord-321013-8pkrg0mx	143	24	/	/	SYM
cord-321013-8pkrg0mx	143	25	icosahedral	icosahedral	JJ
cord-321013-8pkrg0mx	143	26	core	core	NN
cord-321013-8pkrg0mx	143	27	[	[	-LRB-
cord-321013-8pkrg0mx	143	28	81	81	CD
cord-321013-8pkrg0mx	143	29	]	]	-RRB-
cord-321013-8pkrg0mx	143	30	.	.	.
cord-321013-8pkrg0mx	144	1	The	the	DT
cord-321013-8pkrg0mx	144	2	internal	internal	JJ
cord-321013-8pkrg0mx	144	3	core	core	NN
cord-321013-8pkrg0mx	144	4	consists	consist	VBZ
cord-321013-8pkrg0mx	144	5	of	of	IN
cord-321013-8pkrg0mx	144	6	N	n	CD
cord-321013-8pkrg0mx	144	7	protein	protein	NN
cord-321013-8pkrg0mx	144	8	,	,	,
cord-321013-8pkrg0mx	144	9	RNA	RNA	NNP
cord-321013-8pkrg0mx	144	10	and	and	CC
cord-321013-8pkrg0mx	144	11	the	the	DT
cord-321013-8pkrg0mx	144	12	CTD	CTD	NNP
cord-321013-8pkrg0mx	144	13	of	of	IN
cord-321013-8pkrg0mx	144	14	M	M	NNP
cord-321013-8pkrg0mx	144	15	protein	protein	NN
cord-321013-8pkrg0mx	144	16	.	.	.
cord-321013-8pkrg0mx	145	1	The	the	DT
cord-321013-8pkrg0mx	145	2	M	M	NNP
cord-321013-8pkrg0mx	145	3	protein	protein	NN
cord-321013-8pkrg0mx	145	4	is	be	VBZ
cord-321013-8pkrg0mx	145	5	the	the	DT
cord-321013-8pkrg0mx	145	6	main	main	JJ
cord-321013-8pkrg0mx	145	7	core	core	NN
cord-321013-8pkrg0mx	145	8	shell	shell	NN
cord-321013-8pkrg0mx	145	9	component	component	NN
cord-321013-8pkrg0mx	145	10	and	and	CC
cord-321013-8pkrg0mx	145	11	a	a	DT
cord-321013-8pkrg0mx	145	12	16	16	CD
cord-321013-8pkrg0mx	145	13	amino	amino	NN
cord-321013-8pkrg0mx	145	14	acid	acid	NN
cord-321013-8pkrg0mx	145	15	domain	domain	NN
cord-321013-8pkrg0mx	145	16	(	(	-LRB-
cord-321013-8pkrg0mx	145	17	aa	aa	NNP
cord-321013-8pkrg0mx	145	18	237	237	CD
cord-321013-8pkrg0mx	145	19	-	-	HYPH
cord-321013-8pkrg0mx	145	20	252	252	CD
cord-321013-8pkrg0mx	145	21	)	)	-RRB-
cord-321013-8pkrg0mx	145	22	on	on	IN
cord-321013-8pkrg0mx	145	23	the	the	DT
cord-321013-8pkrg0mx	145	24	CTD	CTD	NNP
cord-321013-8pkrg0mx	145	25	of	of	IN
cord-321013-8pkrg0mx	145	26	M	M	NNP
cord-321013-8pkrg0mx	145	27	protein	protein	NN
cord-321013-8pkrg0mx	145	28	binds	bind	VBZ
cord-321013-8pkrg0mx	145	29	directly	directly	RB
cord-321013-8pkrg0mx	145	30	to	to	IN
cord-321013-8pkrg0mx	145	31	N	n	CD
cord-321013-8pkrg0mx	145	32	protein	protein	NN
cord-321013-8pkrg0mx	145	33	via	via	IN
cord-321013-8pkrg0mx	145	34	an	an	DT
cord-321013-8pkrg0mx	145	35	ionic	ionic	JJ
cord-321013-8pkrg0mx	145	36	interaction	interaction	NN
cord-321013-8pkrg0mx	145	37	,	,	,
cord-321013-8pkrg0mx	145	38	leading	lead	VBG
cord-321013-8pkrg0mx	145	39	to	to	IN
cord-321013-8pkrg0mx	145	40	specific	specific	JJ
cord-321013-8pkrg0mx	145	41	genome	genome	NN
cord-321013-8pkrg0mx	145	42	encapsidation	encapsidation	NN
cord-321013-8pkrg0mx	145	43	in	in	IN
cord-321013-8pkrg0mx	145	44	the	the	DT
cord-321013-8pkrg0mx	145	45	budding	bud	VBG
cord-321013-8pkrg0mx	145	46	viral	viral	JJ
cord-321013-8pkrg0mx	145	47	particle	particle	NN
cord-321013-8pkrg0mx	145	48	[	[	-LRB-
cord-321013-8pkrg0mx	145	49	81	81	CD
cord-321013-8pkrg0mx	145	50	]	]	-RRB-
cord-321013-8pkrg0mx	146	1	[	[	-LRB-
cord-321013-8pkrg0mx	146	2	82	82	CD
cord-321013-8pkrg0mx	146	3	]	]	-RRB-
cord-321013-8pkrg0mx	147	1	[	[	-LRB-
cord-321013-8pkrg0mx	147	2	83	83	CD
cord-321013-8pkrg0mx	147	3	]	]	-RRB-
cord-321013-8pkrg0mx	147	4	.The	.The	.
cord-321013-8pkrg0mx	148	1	N	N	NNP
cord-321013-8pkrg0mx	148	2	protein	protein	NN
cord-321013-8pkrg0mx	148	3	therefore	therefore	RB
cord-321013-8pkrg0mx	148	4	plays	play	VBZ
cord-321013-8pkrg0mx	148	5	an	an	DT
cord-321013-8pkrg0mx	148	6	essential	essential	JJ
cord-321013-8pkrg0mx	148	7	structural	structural	JJ
cord-321013-8pkrg0mx	148	8	role	role	NN
cord-321013-8pkrg0mx	148	9	in	in	IN
cord-321013-8pkrg0mx	148	10	the	the	DT
cord-321013-8pkrg0mx	148	11	CoV	cov	NN
cord-321013-8pkrg0mx	148	12	virion	virion	NN
cord-321013-8pkrg0mx	148	13	through	through	IN
cord-321013-8pkrg0mx	148	14	a	a	DT
cord-321013-8pkrg0mx	148	15	network	network	NN
cord-321013-8pkrg0mx	148	16	of	of	IN
cord-321013-8pkrg0mx	148	17	interactions	interaction	NNS
cord-321013-8pkrg0mx	148	18	with	with	IN
cord-321013-8pkrg0mx	148	19	(	(	-LRB-
cord-321013-8pkrg0mx	148	20	i	i	NN
cord-321013-8pkrg0mx	148	21	)	)	-RRB-
cord-321013-8pkrg0mx	148	22	the	the	DT
cord-321013-8pkrg0mx	148	23	genomic	genomic	JJ
cord-321013-8pkrg0mx	148	24	RNA	RNA	NNP
cord-321013-8pkrg0mx	148	25	;	;	,
cord-321013-8pkrg0mx	148	26	(	(	-LRB-
cord-321013-8pkrg0mx	148	27	ii	ii	NN
cord-321013-8pkrg0mx	148	28	)	)	-RRB-
cord-321013-8pkrg0mx	148	29	M	M	NNP
cord-321013-8pkrg0mx	148	30	protein	protein	NN
cord-321013-8pkrg0mx	148	31	and	and	CC
cord-321013-8pkrg0mx	148	32	(	(	-LRB-
cord-321013-8pkrg0mx	148	33	iii	iii	NN
cord-321013-8pkrg0mx	148	34	)	)	-RRB-
cord-321013-8pkrg0mx	148	35	other	other	JJ
cord-321013-8pkrg0mx	148	36	N	n	CD
cord-321013-8pkrg0mx	148	37	proteins	protein	NNS
cord-321013-8pkrg0mx	148	38	.	.	.
cord-321013-8pkrg0mx	149	1	Assembly	assembly	NN
cord-321013-8pkrg0mx	149	2	of	of	IN
cord-321013-8pkrg0mx	149	3	virus	virus	NN
cord-321013-8pkrg0mx	149	4	particles	particle	NNS
cord-321013-8pkrg0mx	149	5	is	be	VBZ
cord-321013-8pkrg0mx	149	6	an	an	DT
cord-321013-8pkrg0mx	149	7	essential	essential	JJ
cord-321013-8pkrg0mx	149	8	step	step	NN
cord-321013-8pkrg0mx	149	9	for	for	IN
cord-321013-8pkrg0mx	149	10	a	a	DT
cord-321013-8pkrg0mx	149	11	productive	productive	JJ
cord-321013-8pkrg0mx	149	12	viral	viral	JJ
cord-321013-8pkrg0mx	149	13	replication	replication	NN
cord-321013-8pkrg0mx	149	14	cycle	cycle	NN
cord-321013-8pkrg0mx	149	15	.	.	.
cord-321013-8pkrg0mx	150	1	CoV	CoV	NNP
cord-321013-8pkrg0mx	150	2	virions	virion	NNS
cord-321013-8pkrg0mx	150	3	contain	contain	VBP
cord-321013-8pkrg0mx	150	4	three	three	CD
cord-321013-8pkrg0mx	150	5	envelope	envelope	NN
cord-321013-8pkrg0mx	150	6	proteins	protein	NNS
cord-321013-8pkrg0mx	150	7	,	,	,
cord-321013-8pkrg0mx	150	8	M	M	NNP
cord-321013-8pkrg0mx	150	9	,	,	,
cord-321013-8pkrg0mx	150	10	E	E	NNP
cord-321013-8pkrg0mx	150	11	and	and	CC
cord-321013-8pkrg0mx	150	12	S	S	NNP
cord-321013-8pkrg0mx	150	13	,	,	,
cord-321013-8pkrg0mx	150	14	and	and	CC
cord-321013-8pkrg0mx	150	15	a	a	DT
cord-321013-8pkrg0mx	150	16	viral	viral	JJ
cord-321013-8pkrg0mx	150	17	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	150	18	,	,	,
cord-321013-8pkrg0mx	150	19	which	which	WDT
cord-321013-8pkrg0mx	150	20	consists	consist	VBZ
cord-321013-8pkrg0mx	150	21	of	of	IN
cord-321013-8pkrg0mx	150	22	genomic	genomic	JJ
cord-321013-8pkrg0mx	150	23	RNA	RNA	NNP
cord-321013-8pkrg0mx	150	24	and	and	CC
cord-321013-8pkrg0mx	150	25	N	N	NNP
cord-321013-8pkrg0mx	150	26	protein	protein	NN
cord-321013-8pkrg0mx	150	27	,	,	,
cord-321013-8pkrg0mx	150	28	within	within	IN
cord-321013-8pkrg0mx	150	29	the	the	DT
cord-321013-8pkrg0mx	150	30	viral	viral	JJ
cord-321013-8pkrg0mx	150	31	envelope	envelope	NN
cord-321013-8pkrg0mx	150	32	.	.	.
cord-321013-8pkrg0mx	151	1	[	[	-LRB-
cord-321013-8pkrg0mx	151	2	87	87	CD
cord-321013-8pkrg0mx	151	3	,	,	,
cord-321013-8pkrg0mx	151	4	88	88	CD
cord-321013-8pkrg0mx	151	5	]	]	-RRB-
cord-321013-8pkrg0mx	151	6	.	.	.
cord-321013-8pkrg0mx	152	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	152	2	is	be	VBZ
cord-321013-8pkrg0mx	152	3	believed	believe	VBN
cord-321013-8pkrg0mx	152	4	that	that	IN
cord-321013-8pkrg0mx	152	5	the	the	DT
cord-321013-8pkrg0mx	152	6	interaction	interaction	NN
cord-321013-8pkrg0mx	152	7	of	of	IN
cord-321013-8pkrg0mx	152	8	the	the	DT
cord-321013-8pkrg0mx	152	9	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	152	10	with	with	IN
cord-321013-8pkrg0mx	152	11	envelope	envelope	NN
cord-321013-8pkrg0mx	152	12	proteins	protein	NNS
cord-321013-8pkrg0mx	152	13	drives	drive	VBZ
cord-321013-8pkrg0mx	152	14	the	the	DT
cord-321013-8pkrg0mx	152	15	incorporation	incorporation	NN
cord-321013-8pkrg0mx	152	16	of	of	IN
cord-321013-8pkrg0mx	152	17	the	the	DT
cord-321013-8pkrg0mx	152	18	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	152	19	in	in	IN
cord-321013-8pkrg0mx	152	20	enveloped	envelop	VBN
cord-321013-8pkrg0mx	152	21	viruses	virus	NNS
cord-321013-8pkrg0mx	152	22	[	[	-LRB-
cord-321013-8pkrg0mx	152	23	89	89	CD
cord-321013-8pkrg0mx	152	24	]	]	-RRB-
cord-321013-8pkrg0mx	152	25	,	,	,
cord-321013-8pkrg0mx	152	26	and	and	CC
cord-321013-8pkrg0mx	152	27	such	such	JJ
cord-321013-8pkrg0mx	152	28	protein	protein	NN
cord-321013-8pkrg0mx	152	29	-	-	HYPH
cord-321013-8pkrg0mx	152	30	protein	protein	NN
cord-321013-8pkrg0mx	152	31	interactions	interaction	NNS
cord-321013-8pkrg0mx	152	32	are	be	VBP
cord-321013-8pkrg0mx	152	33	critical	critical	JJ
cord-321013-8pkrg0mx	152	34	for	for	IN
cord-321013-8pkrg0mx	152	35	viral	viral	JJ
cord-321013-8pkrg0mx	152	36	assembly	assembly	NN
cord-321013-8pkrg0mx	152	37	,	,	,
cord-321013-8pkrg0mx	152	38	as	as	IN
cord-321013-8pkrg0mx	152	39	has	have	VBZ
cord-321013-8pkrg0mx	152	40	been	be	VBN
cord-321013-8pkrg0mx	152	41	shown	show	VBN
cord-321013-8pkrg0mx	152	42	for	for	IN
cord-321013-8pkrg0mx	152	43	alphaviruses	alphavirus	NNS
cord-321013-8pkrg0mx	152	44	[	[	-LRB-
cord-321013-8pkrg0mx	152	45	90	90	CD
cord-321013-8pkrg0mx	152	46	,	,	,
cord-321013-8pkrg0mx	152	47	91	91	CD
cord-321013-8pkrg0mx	152	48	]	]	-RRB-
cord-321013-8pkrg0mx	152	49	.	.	.
cord-321013-8pkrg0mx	153	1	N	N	NNP
cord-321013-8pkrg0mx	153	2	and	and	CC
cord-321013-8pkrg0mx	153	3	M	M	NNP
cord-321013-8pkrg0mx	153	4	proteins	protein	NNS
cord-321013-8pkrg0mx	153	5	are	be	VBP
cord-321013-8pkrg0mx	153	6	the	the	DT
cord-321013-8pkrg0mx	153	7	two	two	CD
cord-321013-8pkrg0mx	153	8	major	major	JJ
cord-321013-8pkrg0mx	153	9	structural	structural	JJ
cord-321013-8pkrg0mx	153	10	proteins	protein	NNS
cord-321013-8pkrg0mx	153	11	in	in	IN
cord-321013-8pkrg0mx	153	12	CoV	cov	NN
cord-321013-8pkrg0mx	153	13	virions	virion	NNS
cord-321013-8pkrg0mx	153	14	[	[	-LRB-
cord-321013-8pkrg0mx	153	15	92	92	CD
cord-321013-8pkrg0mx	153	16	]	]	-RRB-
cord-321013-8pkrg0mx	153	17	.	.	.
cord-321013-8pkrg0mx	154	1	The	the	DT
cord-321013-8pkrg0mx	154	2	M	M	NNP
cord-321013-8pkrg0mx	154	3	protein	protein	NN
cord-321013-8pkrg0mx	154	4	is	be	VBZ
cord-321013-8pkrg0mx	154	5	anchored	anchor	VBN
cord-321013-8pkrg0mx	154	6	by	by	IN
cord-321013-8pkrg0mx	154	7	its	-PRON-	PRP$
cord-321013-8pkrg0mx	154	8	three	three	CD
cord-321013-8pkrg0mx	154	9	transmembrane	transmembrane	NN
cord-321013-8pkrg0mx	154	10	domains	domain	NNS
cord-321013-8pkrg0mx	154	11	to	to	IN
cord-321013-8pkrg0mx	154	12	the	the	DT
cord-321013-8pkrg0mx	154	13	viral	viral	JJ
cord-321013-8pkrg0mx	154	14	envelope	envelope	NN
cord-321013-8pkrg0mx	154	15	and	and	CC
cord-321013-8pkrg0mx	154	16	its	-PRON-	PRP$
cord-321013-8pkrg0mx	154	17	large	large	JJ
cord-321013-8pkrg0mx	154	18	carboxy	carboxy	JJ
cord-321013-8pkrg0mx	154	19	-	-	HYPH
cord-321013-8pkrg0mx	154	20	terminal	terminal	NN
cord-321013-8pkrg0mx	154	21	tail	tail	NN
cord-321013-8pkrg0mx	154	22	in	in	IN
cord-321013-8pkrg0mx	155	1	the	the	DT
cord-321013-8pkrg0mx	155	2	virion	virion	NN
cord-321013-8pkrg0mx	155	3	interior	interior	NN
cord-321013-8pkrg0mx	155	4	interacts	interact	VBZ
cord-321013-8pkrg0mx	155	5	with	with	IN
cord-321013-8pkrg0mx	155	6	the	the	DT
cord-321013-8pkrg0mx	155	7	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	155	8	[	[	-LRB-
cord-321013-8pkrg0mx	155	9	93	93	CD
cord-321013-8pkrg0mx	155	10	]	]	-RRB-
cord-321013-8pkrg0mx	155	11	.	.	.
cord-321013-8pkrg0mx	156	1	The	the	DT
cord-321013-8pkrg0mx	156	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	156	3	consists	consist	VBZ
cord-321013-8pkrg0mx	156	4	of	of	IN
cord-321013-8pkrg0mx	156	5	the	the	DT
cord-321013-8pkrg0mx	156	6	positive	positive	JJ
cord-321013-8pkrg0mx	156	7	strand	strand	NN
cord-321013-8pkrg0mx	156	8	genomic	genomic	JJ
cord-321013-8pkrg0mx	156	9	RNA	RNA	NNP
cord-321013-8pkrg0mx	156	10	,	,	,
cord-321013-8pkrg0mx	156	11	mRNA	mrna	NN
cord-321013-8pkrg0mx	156	12	1	1	CD
cord-321013-8pkrg0mx	156	13	,	,	,
cord-321013-8pkrg0mx	156	14	helically	helically	NNP
cord-321013-8pkrg0mx	156	15	encapsidated	encapsidate	VBN
cord-321013-8pkrg0mx	156	16	by	by	IN
cord-321013-8pkrg0mx	156	17	N	n	CD
cord-321013-8pkrg0mx	156	18	protein	protein	NN
cord-321013-8pkrg0mx	156	19	monomers	monomer	NNS
cord-321013-8pkrg0mx	156	20	,	,	,
cord-321013-8pkrg0mx	156	21	and	and	CC
cord-321013-8pkrg0mx	156	22	the	the	DT
cord-321013-8pkrg0mx	156	23	N	N	NNP
cord-321013-8pkrg0mx	156	24	protein	protein	NN
cord-321013-8pkrg0mx	156	25	region	region	NN
cord-321013-8pkrg0mx	156	26	that	that	WDT
cord-321013-8pkrg0mx	156	27	interacts	interact	VBZ
cord-321013-8pkrg0mx	156	28	with	with	IN
cord-321013-8pkrg0mx	156	29	the	the	DT
cord-321013-8pkrg0mx	156	30	C	c	NN
cord-321013-8pkrg0mx	156	31	-	-	HYPH
cord-321013-8pkrg0mx	156	32	terminus	terminus	NN
cord-321013-8pkrg0mx	156	33	of	of	IN
cord-321013-8pkrg0mx	156	34	the	the	DT
cord-321013-8pkrg0mx	156	35	M	M	NNP
cord-321013-8pkrg0mx	156	36	protein	protein	NN
cord-321013-8pkrg0mx	156	37	domain	domain	NN
cord-321013-8pkrg0mx	156	38	seems	seem	VBZ
cord-321013-8pkrg0mx	156	39	to	to	TO
cord-321013-8pkrg0mx	156	40	be	be	VB
cord-321013-8pkrg0mx	156	41	CoV	CoV	NNP
cord-321013-8pkrg0mx	156	42	specific	specific	JJ
cord-321013-8pkrg0mx	156	43	.	.	.
cord-321013-8pkrg0mx	157	1	The	the	DT
cord-321013-8pkrg0mx	157	2	intracellular	intracellular	JJ
cord-321013-8pkrg0mx	157	3	sites	site	NNS
cord-321013-8pkrg0mx	157	4	of	of	IN
cord-321013-8pkrg0mx	157	5	virus	virus	NN
cord-321013-8pkrg0mx	157	6	assembly	assembly	NN
cord-321013-8pkrg0mx	157	7	also	also	RB
cord-321013-8pkrg0mx	157	8	vary	vary	VBP
cord-321013-8pkrg0mx	157	9	among	among	IN
cord-321013-8pkrg0mx	157	10	different	different	JJ
cord-321013-8pkrg0mx	157	11	viruses	virus	NNS
cord-321013-8pkrg0mx	157	12	[	[	-LRB-
cord-321013-8pkrg0mx	157	13	94	94	CD
cord-321013-8pkrg0mx	157	14	,	,	,
cord-321013-8pkrg0mx	157	15	95	95	CD
cord-321013-8pkrg0mx	157	16	]	]	-RRB-
cord-321013-8pkrg0mx	157	17	.	.	.
cord-321013-8pkrg0mx	158	1	In	in	IN
cord-321013-8pkrg0mx	158	2	MHV	MHV	NNP
cord-321013-8pkrg0mx	158	3	,	,	,
cord-321013-8pkrg0mx	158	4	the	the	DT
cord-321013-8pkrg0mx	158	5	large	large	JJ
cord-321013-8pkrg0mx	158	6	carboxy	carboxy	JJ
cord-321013-8pkrg0mx	158	7	-	-	HYPH
cord-321013-8pkrg0mx	158	8	terminal	terminal	NN
cord-321013-8pkrg0mx	158	9	domain	domain	NN
cord-321013-8pkrg0mx	158	10	of	of	IN
cord-321013-8pkrg0mx	158	11	the	the	DT
cord-321013-8pkrg0mx	158	12	M	M	NNP
cord-321013-8pkrg0mx	158	13	protein	protein	NN
cord-321013-8pkrg0mx	158	14	interacts	interact	VBZ
cord-321013-8pkrg0mx	158	15	with	with	IN
cord-321013-8pkrg0mx	158	16	the	the	DT
cord-321013-8pkrg0mx	158	17	CTD	CTD	NNP
cord-321013-8pkrg0mx	158	18	of	of	IN
cord-321013-8pkrg0mx	158	19	the	the	DT
cord-321013-8pkrg0mx	158	20	N	N	NNP
cord-321013-8pkrg0mx	158	21	protein	protein	NN
cord-321013-8pkrg0mx	158	22	[	[	-LRB-
cord-321013-8pkrg0mx	158	23	93	93	CD
cord-321013-8pkrg0mx	158	24	]	]	-RRB-
cord-321013-8pkrg0mx	158	25	.	.	.
cord-321013-8pkrg0mx	159	1	Newly	newly	RB
cord-321013-8pkrg0mx	159	2	synthesized	synthesize	VBN
cord-321013-8pkrg0mx	159	3	,	,	,
cord-321013-8pkrg0mx	159	4	unglycosylated	unglycosylated	NNP
cord-321013-8pkrg0mx	159	5	M	M	NNP
cord-321013-8pkrg0mx	159	6	protein	protein	NN
cord-321013-8pkrg0mx	159	7	interacts	interact	VBZ
cord-321013-8pkrg0mx	159	8	with	with	IN
cord-321013-8pkrg0mx	159	9	N	n	CD
cord-321013-8pkrg0mx	159	10	protein	protein	NN
cord-321013-8pkrg0mx	159	11	at	at	IN
cord-321013-8pkrg0mx	159	12	the	the	DT
cord-321013-8pkrg0mx	159	13	ER	ER	NNP
cord-321013-8pkrg0mx	159	14	membrane	membrane	NN
cord-321013-8pkrg0mx	159	15	,	,	,
cord-321013-8pkrg0mx	159	16	which	which	WDT
cord-321013-8pkrg0mx	159	17	is	be	VBZ
cord-321013-8pkrg0mx	159	18	a	a	DT
cord-321013-8pkrg0mx	159	19	pre	pre	JJ
cord-321013-8pkrg0mx	159	20	-	-	JJ
cord-321013-8pkrg0mx	159	21	Golgi	golgi	JJ
cord-321013-8pkrg0mx	159	22	compartment	compartment	NN
cord-321013-8pkrg0mx	159	23	that	that	WDT
cord-321013-8pkrg0mx	159	24	is	be	VBZ
cord-321013-8pkrg0mx	159	25	also	also	RB
cord-321013-8pkrg0mx	159	26	the	the	DT
cord-321013-8pkrg0mx	159	27	site	site	NN
cord-321013-8pkrg0mx	159	28	of	of	IN
cord-321013-8pkrg0mx	159	29	MHV	MHV	NNP
cord-321013-8pkrg0mx	159	30	budding	bud	VBG
cord-321013-8pkrg0mx	159	31	[	[	-LRB-
cord-321013-8pkrg0mx	159	32	96	96	CD
cord-321013-8pkrg0mx	159	33	]	]	-RRB-
cord-321013-8pkrg0mx	159	34	,	,	,
cord-321013-8pkrg0mx	159	35	suggesting	suggest	VBG
cord-321013-8pkrg0mx	159	36	that	that	IN
cord-321013-8pkrg0mx	159	37	the	the	DT
cord-321013-8pkrg0mx	159	38	site	site	NN
cord-321013-8pkrg0mx	159	39	of	of	IN
cord-321013-8pkrg0mx	159	40	interaction	interaction	NN
cord-321013-8pkrg0mx	159	41	overlays	overlay	NNS
cord-321013-8pkrg0mx	159	42	with	with	IN
cord-321013-8pkrg0mx	159	43	MHV	mhv	NN
cord-321013-8pkrg0mx	159	44	budding	bud	VBG
cord-321013-8pkrg0mx	159	45	sites	site	NNS
cord-321013-8pkrg0mx	159	46	[	[	-LRB-
cord-321013-8pkrg0mx	159	47	93	93	CD
cord-321013-8pkrg0mx	159	48	]	]	-RRB-
cord-321013-8pkrg0mx	159	49	.	.	.
cord-321013-8pkrg0mx	160	1	The	the	DT
cord-321013-8pkrg0mx	160	2	M	M	NNP
cord-321013-8pkrg0mx	160	3	protein	protein	NN
cord-321013-8pkrg0mx	160	4	-	-	HYPH
cord-321013-8pkrg0mx	160	5	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	160	6	interaction	interaction	NN
cord-321013-8pkrg0mx	160	7	is	be	VBZ
cord-321013-8pkrg0mx	160	8	thought	think	VBN
cord-321013-8pkrg0mx	160	9	to	to	TO
cord-321013-8pkrg0mx	160	10	be	be	VB
cord-321013-8pkrg0mx	160	11	initiated	initiate	VBN
cord-321013-8pkrg0mx	160	12	by	by	IN
cord-321013-8pkrg0mx	160	13	a	a	DT
cord-321013-8pkrg0mx	160	14	direct	direct	JJ
cord-321013-8pkrg0mx	160	15	binding	binding	NN
cord-321013-8pkrg0mx	160	16	of	of	IN
cord-321013-8pkrg0mx	160	17	M	M	NNP
cord-321013-8pkrg0mx	160	18	protein	protein	NN
cord-321013-8pkrg0mx	160	19	to	to	IN
cord-321013-8pkrg0mx	160	20	genomic	genomic	JJ
cord-321013-8pkrg0mx	160	21	RNA	RNA	NNP
cord-321013-8pkrg0mx	160	22	that	that	WDT
cord-321013-8pkrg0mx	160	23	is	be	VBZ
cord-321013-8pkrg0mx	160	24	mediated	mediate	VBN
cord-321013-8pkrg0mx	160	25	by	by	IN
cord-321013-8pkrg0mx	160	26	a	a	DT
cord-321013-8pkrg0mx	160	27	69	69	CD
cord-321013-8pkrg0mx	160	28	nucleotide	nucleotide	NN
cord-321013-8pkrg0mx	160	29	(	(	-LRB-
cord-321013-8pkrg0mx	160	30	nt	nt	RB
cord-321013-8pkrg0mx	160	31	)	)	-RRB-
cord-321013-8pkrg0mx	160	32	packaging	packaging	NN
cord-321013-8pkrg0mx	160	33	signal	signal	NN
cord-321013-8pkrg0mx	160	34	(	(	-LRB-
cord-321013-8pkrg0mx	160	35	ps	ps	NNP
cord-321013-8pkrg0mx	160	36	)	)	-RRB-
cord-321013-8pkrg0mx	160	37	present	present	VBP
cord-321013-8pkrg0mx	160	38	only	only	RB
cord-321013-8pkrg0mx	160	39	on	on	IN
cord-321013-8pkrg0mx	160	40	the	the	DT
cord-321013-8pkrg0mx	160	41	mRNA	mRNA	NNP
cord-321013-8pkrg0mx	160	42	1	1	CD
cord-321013-8pkrg0mx	160	43	association	association	NN
cord-321013-8pkrg0mx	160	44	[	[	-LRB-
cord-321013-8pkrg0mx	160	45	93	93	CD
cord-321013-8pkrg0mx	160	46	,	,	,
cord-321013-8pkrg0mx	160	47	97	97	CD
cord-321013-8pkrg0mx	160	48	]	]	-RRB-
cord-321013-8pkrg0mx	160	49	.	.	.
cord-321013-8pkrg0mx	161	1	These	these	DT
cord-321013-8pkrg0mx	161	2	ps	ps	NNP
cord-321013-8pkrg0mx	161	3	is	be	VBZ
cord-321013-8pkrg0mx	161	4	located	locate	VBN
cord-321013-8pkrg0mx	161	5	about	about	IN
cord-321013-8pkrg0mx	161	6	21	21	CD
cord-321013-8pkrg0mx	161	7	kb	kb	NNS
cord-321013-8pkrg0mx	161	8	from	from	IN
cord-321013-8pkrg0mx	161	9	the	the	DT
cord-321013-8pkrg0mx	161	10	5	5	CD
cord-321013-8pkrg0mx	161	11	'	'	NN
cord-321013-8pkrg0mx	161	12	end	end	NN
cord-321013-8pkrg0mx	161	13	of	of	IN
cord-321013-8pkrg0mx	161	14	MHV	MHV	NNP
cord-321013-8pkrg0mx	161	15	mRNA	mrna	NN
cord-321013-8pkrg0mx	161	16	1	1	CD
cord-321013-8pkrg0mx	161	17	[	[	-LRB-
cord-321013-8pkrg0mx	161	18	97	97	CD
cord-321013-8pkrg0mx	161	19	,	,	,
cord-321013-8pkrg0mx	161	20	98	98	CD
cord-321013-8pkrg0mx	161	21	]	]	-RRB-
cord-321013-8pkrg0mx	161	22	,	,	,
cord-321013-8pkrg0mx	161	23	is	be	VBZ
cord-321013-8pkrg0mx	161	24	necessary	necessary	JJ
cord-321013-8pkrg0mx	161	25	and	and	CC
cord-321013-8pkrg0mx	161	26	sufficient	sufficient	JJ
cord-321013-8pkrg0mx	161	27	for	for	IN
cord-321013-8pkrg0mx	161	28	packaging	package	VBG
cord-321013-8pkrg0mx	161	29	RNA	RNA	NNP
cord-321013-8pkrg0mx	161	30	into	into	IN
cord-321013-8pkrg0mx	161	31	MHV	MHV	NNP
cord-321013-8pkrg0mx	161	32	particles	particle	NNS
cord-321013-8pkrg0mx	161	33	[	[	-LRB-
cord-321013-8pkrg0mx	161	34	99	99	CD
cord-321013-8pkrg0mx	161	35	]	]	-RRB-
cord-321013-8pkrg0mx	161	36	,	,	,
cord-321013-8pkrg0mx	161	37	and	and	CC
cord-321013-8pkrg0mx	161	38	it	-PRON-	PRP
cord-321013-8pkrg0mx	161	39	has	have	VBZ
cord-321013-8pkrg0mx	161	40	been	be	VBN
cord-321013-8pkrg0mx	161	41	suggested	suggest	VBN
cord-321013-8pkrg0mx	161	42	that	that	IN
cord-321013-8pkrg0mx	161	43	the	the	DT
cord-321013-8pkrg0mx	161	44	M	M	NNP
cord-321013-8pkrg0mx	161	45	protein	protein	NN
cord-321013-8pkrg0mx	161	46	-	-	HYPH
cord-321013-8pkrg0mx	161	47	ps	ps	NN
cord-321013-8pkrg0mx	161	48	interaction	interaction	NN
cord-321013-8pkrg0mx	161	49	could	could	MD
cord-321013-8pkrg0mx	161	50	lead	lead	VB
cord-321013-8pkrg0mx	161	51	to	to	IN
cord-321013-8pkrg0mx	161	52	the	the	DT
cord-321013-8pkrg0mx	161	53	association	association	NN
cord-321013-8pkrg0mx	161	54	of	of	IN
cord-321013-8pkrg0mx	161	55	M	M	NNP
cord-321013-8pkrg0mx	161	56	protein	protein	NN
cord-321013-8pkrg0mx	161	57	with	with	IN
cord-321013-8pkrg0mx	161	58	N	n	CD
cord-321013-8pkrg0mx	161	59	protein	protein	NN
cord-321013-8pkrg0mx	161	60	,	,	,
cord-321013-8pkrg0mx	161	61	thereby	thereby	RB
cord-321013-8pkrg0mx	161	62	stabilizing	stabilize	VBG
cord-321013-8pkrg0mx	161	63	the	the	DT
cord-321013-8pkrg0mx	161	64	complex	complex	NN
cord-321013-8pkrg0mx	161	65	between	between	IN
cord-321013-8pkrg0mx	161	66	M	M	NNP
cord-321013-8pkrg0mx	161	67	protein	protein	NN
cord-321013-8pkrg0mx	161	68	and	and	CC
cord-321013-8pkrg0mx	161	69	the	the	DT
cord-321013-8pkrg0mx	161	70	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	161	71	[	[	-LRB-
cord-321013-8pkrg0mx	161	72	93	93	CD
cord-321013-8pkrg0mx	161	73	]	]	-RRB-
cord-321013-8pkrg0mx	161	74	.	.	.
cord-321013-8pkrg0mx	162	1	Although	although	IN
cord-321013-8pkrg0mx	162	2	the	the	DT
cord-321013-8pkrg0mx	162	3	M	M	NNP
cord-321013-8pkrg0mx	162	4	protein	protein	NN
cord-321013-8pkrg0mx	162	5	-	-	HYPH
cord-321013-8pkrg0mx	162	6	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	162	7	interaction	interaction	NN
cord-321013-8pkrg0mx	162	8	could	could	MD
cord-321013-8pkrg0mx	162	9	theoretically	theoretically	RB
cord-321013-8pkrg0mx	162	10	also	also	RB
cord-321013-8pkrg0mx	162	11	be	be	VB
cord-321013-8pkrg0mx	162	12	initiated	initiate	VBN
cord-321013-8pkrg0mx	162	13	by	by	IN
cord-321013-8pkrg0mx	162	14	direct	direct	JJ
cord-321013-8pkrg0mx	162	15	binding	binding	NN
cord-321013-8pkrg0mx	162	16	of	of	IN
cord-321013-8pkrg0mx	162	17	N	n	CD
cord-321013-8pkrg0mx	162	18	protein	protein	NN
cord-321013-8pkrg0mx	162	19	to	to	IN
cord-321013-8pkrg0mx	162	20	genomic	genomic	JJ
cord-321013-8pkrg0mx	162	21	RNA	RNA	NNP
cord-321013-8pkrg0mx	162	22	,	,	,
cord-321013-8pkrg0mx	162	23	this	this	DT
cord-321013-8pkrg0mx	162	24	is	be	VBZ
cord-321013-8pkrg0mx	162	25	unlikely	unlikely	JJ
cord-321013-8pkrg0mx	162	26	because	because	IN
cord-321013-8pkrg0mx	162	27	N	n	CD
cord-321013-8pkrg0mx	162	28	protein	protein	NN
cord-321013-8pkrg0mx	162	29	interacts	interact	VBZ
cord-321013-8pkrg0mx	162	30	with	with	IN
cord-321013-8pkrg0mx	162	31	all	all	DT
cord-321013-8pkrg0mx	162	32	mRNAs	mrnas	CD
cord-321013-8pkrg0mx	162	33	[	[	-LRB-
cord-321013-8pkrg0mx	162	34	79	79	CD
cord-321013-8pkrg0mx	162	35	,	,	,
cord-321013-8pkrg0mx	162	36	93	93	CD
cord-321013-8pkrg0mx	162	37	]	]	-RRB-
cord-321013-8pkrg0mx	162	38	,	,	,
cord-321013-8pkrg0mx	162	39	which	which	WDT
cord-321013-8pkrg0mx	162	40	makes	make	VBZ
cord-321013-8pkrg0mx	162	41	it	-PRON-	PRP
cord-321013-8pkrg0mx	162	42	difficult	difficult	JJ
cord-321013-8pkrg0mx	162	43	to	to	TO
cord-321013-8pkrg0mx	162	44	explain	explain	VB
cord-321013-8pkrg0mx	162	45	how	how	WRB
cord-321013-8pkrg0mx	162	46	the	the	DT
cord-321013-8pkrg0mx	162	47	formation	formation	NN
cord-321013-8pkrg0mx	162	48	of	of	IN
cord-321013-8pkrg0mx	162	49	N	n	CD
cord-321013-8pkrg0mx	162	50	protein	protein	NN
cord-321013-8pkrg0mx	162	51	-	-	HYPH
cord-321013-8pkrg0mx	162	52	mRNA	mrna	NN
cord-321013-8pkrg0mx	162	53	1	1	CD
cord-321013-8pkrg0mx	162	54	RNP	RNP	NNP
cord-321013-8pkrg0mx	162	55	complex	complex	NN
cord-321013-8pkrg0mx	162	56	might	may	MD
cord-321013-8pkrg0mx	162	57	lead	lead	VB
cord-321013-8pkrg0mx	162	58	to	to	IN
cord-321013-8pkrg0mx	162	59	specific	specific	JJ
cord-321013-8pkrg0mx	162	60	packaging	packaging	NN
cord-321013-8pkrg0mx	162	61	of	of	IN
cord-321013-8pkrg0mx	162	62	genomic	genomic	JJ
cord-321013-8pkrg0mx	162	63	RNA	RNA	NNP
cord-321013-8pkrg0mx	162	64	,	,	,
cord-321013-8pkrg0mx	162	65	and	and	CC
cord-321013-8pkrg0mx	162	66	not	not	RB
cord-321013-8pkrg0mx	162	67	sgRNA	sgRNA	VBG
cord-321013-8pkrg0mx	162	68	,	,	,
cord-321013-8pkrg0mx	162	69	into	into	IN
cord-321013-8pkrg0mx	162	70	virus	virus	NN
cord-321013-8pkrg0mx	162	71	particles	particle	NNS
cord-321013-8pkrg0mx	162	72	[	[	-LRB-
cord-321013-8pkrg0mx	162	73	100	100	CD
cord-321013-8pkrg0mx	162	74	]	]	-RRB-
cord-321013-8pkrg0mx	162	75	.	.	.
cord-321013-8pkrg0mx	163	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	163	2	has	have	VBZ
cord-321013-8pkrg0mx	163	3	since	since	IN
cord-321013-8pkrg0mx	163	4	been	be	VBN
cord-321013-8pkrg0mx	163	5	conclusively	conclusively	RB
cord-321013-8pkrg0mx	163	6	demonstrated	demonstrate	VBN
cord-321013-8pkrg0mx	163	7	that	that	IN
cord-321013-8pkrg0mx	163	8	M	M	NNP
cord-321013-8pkrg0mx	163	9	protein	protein	NN
cord-321013-8pkrg0mx	163	10	selectively	selectively	RB
cord-321013-8pkrg0mx	163	11	interacts	interact	VBZ
cord-321013-8pkrg0mx	163	12	with	with	IN
cord-321013-8pkrg0mx	163	13	ps	ps	NNP
cord-321013-8pkrg0mx	163	14	-	-	HYPH
cord-321013-8pkrg0mx	163	15	containing	contain	VBG
cord-321013-8pkrg0mx	163	16	RNA	RNA	NNP
cord-321013-8pkrg0mx	163	17	in	in	IN
cord-321013-8pkrg0mx	163	18	the	the	DT
cord-321013-8pkrg0mx	163	19	absence	absence	NN
cord-321013-8pkrg0mx	163	20	of	of	IN
cord-321013-8pkrg0mx	163	21	N	n	CD
cord-321013-8pkrg0mx	163	22	protein	protein	NN
cord-321013-8pkrg0mx	163	23	,	,	,
cord-321013-8pkrg0mx	163	24	indicating	indicate	VBG
cord-321013-8pkrg0mx	163	25	that	that	IN
cord-321013-8pkrg0mx	163	26	the	the	DT
cord-321013-8pkrg0mx	163	27	mechanism	mechanism	NN
cord-321013-8pkrg0mx	163	28	of	of	IN
cord-321013-8pkrg0mx	163	29	M	M	NNP
cord-321013-8pkrg0mx	163	30	-	-	HYPH
cord-321013-8pkrg0mx	163	31	ps	ps	NNP
cord-321013-8pkrg0mx	163	32	recognition	recognition	NN
cord-321013-8pkrg0mx	163	33	does	do	VBZ
cord-321013-8pkrg0mx	163	34	not	not	RB
cord-321013-8pkrg0mx	163	35	require	require	VB
cord-321013-8pkrg0mx	163	36	the	the	DT
cord-321013-8pkrg0mx	163	37	formation	formation	NN
cord-321013-8pkrg0mx	163	38	of	of	IN
cord-321013-8pkrg0mx	163	39	RNP	RNP	NNP
cord-321013-8pkrg0mx	163	40	complex	complex	NN
cord-321013-8pkrg0mx	163	41	by	by	IN
cord-321013-8pkrg0mx	163	42	N	n	CD
cord-321013-8pkrg0mx	163	43	protein	protein	NN
cord-321013-8pkrg0mx	163	44	,	,	,
cord-321013-8pkrg0mx	163	45	and	and	CC
cord-321013-8pkrg0mx	163	46	in	in	IN
cord-321013-8pkrg0mx	163	47	fact	fact	NN
cord-321013-8pkrg0mx	163	48	,	,	,
cord-321013-8pkrg0mx	163	49	N	N	NNP
cord-321013-8pkrg0mx	163	50	protein	protein	NN
cord-321013-8pkrg0mx	163	51	is	be	VBZ
cord-321013-8pkrg0mx	163	52	not	not	RB
cord-321013-8pkrg0mx	163	53	required	require	VBN
cord-321013-8pkrg0mx	163	54	for	for	IN
cord-321013-8pkrg0mx	163	55	RNA	RNA	NNP
cord-321013-8pkrg0mx	163	56	packaging	packaging	NN
cord-321013-8pkrg0mx	163	57	in	in	IN
cord-321013-8pkrg0mx	163	58	that	that	DT
cord-321013-8pkrg0mx	163	59	model	model	NN
cord-321013-8pkrg0mx	163	60	[	[	-LRB-
cord-321013-8pkrg0mx	163	61	100	100	CD
cord-321013-8pkrg0mx	163	62	]	]	-RRB-
cord-321013-8pkrg0mx	163	63	.	.	.
cord-321013-8pkrg0mx	164	1	MHV	MHV	NNP
cord-321013-8pkrg0mx	164	2	M	M	NNP
cord-321013-8pkrg0mx	164	3	protein	protein	NN
cord-321013-8pkrg0mx	164	4	was	be	VBD
cord-321013-8pkrg0mx	164	5	the	the	DT
cord-321013-8pkrg0mx	164	6	first	first	JJ
cord-321013-8pkrg0mx	164	7	example	example	NN
cord-321013-8pkrg0mx	164	8	of	of	IN
cord-321013-8pkrg0mx	164	9	a	a	DT
cord-321013-8pkrg0mx	164	10	viral	viral	JJ
cord-321013-8pkrg0mx	164	11	transmembrane	transmembrane	NN
cord-321013-8pkrg0mx	164	12	protein	protein	NN
cord-321013-8pkrg0mx	164	13	that	that	WDT
cord-321013-8pkrg0mx	164	14	could	could	MD
cord-321013-8pkrg0mx	164	15	bind	bind	VB
cord-321013-8pkrg0mx	164	16	to	to	IN
cord-321013-8pkrg0mx	164	17	a	a	DT
cord-321013-8pkrg0mx	164	18	specific	specific	JJ
cord-321013-8pkrg0mx	164	19	viral	viral	JJ
cord-321013-8pkrg0mx	164	20	RNA	RNA	NNP
cord-321013-8pkrg0mx	164	21	element	element	NN
cord-321013-8pkrg0mx	164	22	in	in	IN
cord-321013-8pkrg0mx	164	23	the	the	DT
cord-321013-8pkrg0mx	164	24	absence	absence	NN
cord-321013-8pkrg0mx	164	25	of	of	IN
cord-321013-8pkrg0mx	164	26	any	any	DT
cord-321013-8pkrg0mx	164	27	other	other	JJ
cord-321013-8pkrg0mx	164	28	viral	viral	JJ
cord-321013-8pkrg0mx	164	29	structural	structural	JJ
cord-321013-8pkrg0mx	164	30	proteins	protein	NNS
cord-321013-8pkrg0mx	164	31	[	[	-LRB-
cord-321013-8pkrg0mx	164	32	100	100	CD
cord-321013-8pkrg0mx	164	33	]	]	-RRB-
cord-321013-8pkrg0mx	164	34	,	,	,
cord-321013-8pkrg0mx	164	35	and	and	CC
cord-321013-8pkrg0mx	164	36	a	a	DT
cord-321013-8pkrg0mx	164	37	proposed	propose	VBN
cord-321013-8pkrg0mx	164	38	model	model	NN
cord-321013-8pkrg0mx	164	39	for	for	IN
cord-321013-8pkrg0mx	164	40	RNA	RNA	NNP
cord-321013-8pkrg0mx	164	41	packaging	packaging	NN
cord-321013-8pkrg0mx	164	42	in	in	IN
cord-321013-8pkrg0mx	164	43	MHV	MHV	NNP
cord-321013-8pkrg0mx	164	44	suggests	suggest	VBZ
cord-321013-8pkrg0mx	164	45	that	that	IN
cord-321013-8pkrg0mx	164	46	once	once	RB
cord-321013-8pkrg0mx	164	47	M	M	NNP
cord-321013-8pkrg0mx	164	48	protein	protein	NN
cord-321013-8pkrg0mx	164	49	accumulates	accumulate	VBZ
cord-321013-8pkrg0mx	164	50	and	and	CC
cord-321013-8pkrg0mx	164	51	oligomerizes	oligomerize	NNS
cord-321013-8pkrg0mx	164	52	in	in	IN
cord-321013-8pkrg0mx	164	53	the	the	DT
cord-321013-8pkrg0mx	164	54	intermediate	intermediate	JJ
cord-321013-8pkrg0mx	164	55	compartment	compartment	NN
cord-321013-8pkrg0mx	164	56	between	between	IN
cord-321013-8pkrg0mx	164	57	the	the	DT
cord-321013-8pkrg0mx	164	58	ER	ER	NNP
cord-321013-8pkrg0mx	164	59	and	and	CC
cord-321013-8pkrg0mx	164	60	Golgi	Golgi	NNP
cord-321013-8pkrg0mx	164	61	complex	complex	NN
cord-321013-8pkrg0mx	164	62	,	,	,
cord-321013-8pkrg0mx	164	63	M	M	NNP
cord-321013-8pkrg0mx	164	64	protein	protein	NN
cord-321013-8pkrg0mx	164	65	binds	bind	VBZ
cord-321013-8pkrg0mx	164	66	to	to	IN
cord-321013-8pkrg0mx	164	67	ps	ps	NNP
cord-321013-8pkrg0mx	164	68	-	-	HYPH
cord-321013-8pkrg0mx	164	69	mRNA	mRNA	NNP
cord-321013-8pkrg0mx	164	70	1	1	CD
cord-321013-8pkrg0mx	164	71	,	,	,
cord-321013-8pkrg0mx	164	72	and	and	CC
cord-321013-8pkrg0mx	164	73	only	only	RB
cord-321013-8pkrg0mx	164	74	thereafter	thereafter	RB
cord-321013-8pkrg0mx	164	75	does	do	VBZ
cord-321013-8pkrg0mx	164	76	N	N	NNP
cord-321013-8pkrg0mx	164	77	protein	protein	NN
cord-321013-8pkrg0mx	164	78	associated	associate	VBN
cord-321013-8pkrg0mx	164	79	with	with	IN
cord-321013-8pkrg0mx	164	80	mRNA	mRNA	NNP
cord-321013-8pkrg0mx	164	81	1	1	CD
cord-321013-8pkrg0mx	164	82	interact	interact	VBP
cord-321013-8pkrg0mx	164	83	with	with	IN
cord-321013-8pkrg0mx	164	84	oligomerized	oligomerize	VBN
cord-321013-8pkrg0mx	164	85	M	M	NNP
cord-321013-8pkrg0mx	164	86	protein	protein	NN
cord-321013-8pkrg0mx	164	87	[	[	-LRB-
cord-321013-8pkrg0mx	164	88	100	100	CD
cord-321013-8pkrg0mx	164	89	]	]	-RRB-
cord-321013-8pkrg0mx	164	90	.	.	.
cord-321013-8pkrg0mx	165	1	Although	although	IN
cord-321013-8pkrg0mx	165	2	N	n	CD
cord-321013-8pkrg0mx	165	3	protein	protein	NN
cord-321013-8pkrg0mx	165	4	appears	appear	VBZ
cord-321013-8pkrg0mx	165	5	to	to	TO
cord-321013-8pkrg0mx	165	6	be	be	VB
cord-321013-8pkrg0mx	165	7	dispensable	dispensable	JJ
cord-321013-8pkrg0mx	165	8	for	for	IN
cord-321013-8pkrg0mx	165	9	MHV	MHV	NNP
cord-321013-8pkrg0mx	165	10	RNA	RNA	NNP
cord-321013-8pkrg0mx	165	11	packaging	packaging	NN
cord-321013-8pkrg0mx	165	12	,	,	,
cord-321013-8pkrg0mx	165	13	N	N	NNP
cord-321013-8pkrg0mx	165	14	-	-	HYPH
cord-321013-8pkrg0mx	165	15	M	M	NNP
cord-321013-8pkrg0mx	165	16	interaction	interaction	NN
cord-321013-8pkrg0mx	165	17	might	may	MD
cord-321013-8pkrg0mx	165	18	be	be	VB
cord-321013-8pkrg0mx	165	19	important	important	JJ
cord-321013-8pkrg0mx	165	20	in	in	IN
cord-321013-8pkrg0mx	165	21	compensating	compensate	VBG
cord-321013-8pkrg0mx	165	22	for	for	IN
cord-321013-8pkrg0mx	165	23	viral	viral	JJ
cord-321013-8pkrg0mx	165	24	envelope	envelope	NN
cord-321013-8pkrg0mx	165	25	defects	defect	NNS
cord-321013-8pkrg0mx	165	26	that	that	WDT
cord-321013-8pkrg0mx	165	27	occur	occur	VBP
cord-321013-8pkrg0mx	165	28	due	due	JJ
cord-321013-8pkrg0mx	165	29	to	to	IN
cord-321013-8pkrg0mx	165	30	M	M	NNP
cord-321013-8pkrg0mx	165	31	protein	protein	NN
cord-321013-8pkrg0mx	165	32	mutation	mutation	NN
cord-321013-8pkrg0mx	165	33	.	.	.
cord-321013-8pkrg0mx	166	1	The	the	DT
cord-321013-8pkrg0mx	166	2	M	M	NNP
cord-321013-8pkrg0mx	166	3	protein	protein	NN
cord-321013-8pkrg0mx	166	4	carboxy	carboxy	NN
cord-321013-8pkrg0mx	166	5	terminus	terminus	NN
cord-321013-8pkrg0mx	166	6	is	be	VBZ
cord-321013-8pkrg0mx	166	7	extremely	extremely	RB
cord-321013-8pkrg0mx	166	8	sensitive	sensitive	JJ
cord-321013-8pkrg0mx	166	9	to	to	IN
cord-321013-8pkrg0mx	166	10	mutations	mutation	NNS
cord-321013-8pkrg0mx	166	11	,	,	,
cord-321013-8pkrg0mx	166	12	and	and	CC
cord-321013-8pkrg0mx	166	13	removal	removal	NN
cord-321013-8pkrg0mx	166	14	of	of	IN
cord-321013-8pkrg0mx	166	15	even	even	RB
cord-321013-8pkrg0mx	166	16	only	only	RB
cord-321013-8pkrg0mx	166	17	the	the	DT
cord-321013-8pkrg0mx	166	18	last	last	JJ
cord-321013-8pkrg0mx	166	19	two	two	CD
cord-321013-8pkrg0mx	166	20	amino	amino	NN
cord-321013-8pkrg0mx	166	21	acid	acid	NN
cord-321013-8pkrg0mx	166	22	residues	residue	NNS
cord-321013-8pkrg0mx	166	23	from	from	IN
cord-321013-8pkrg0mx	166	24	the	the	DT
cord-321013-8pkrg0mx	166	25	tail	tail	NN
cord-321013-8pkrg0mx	166	26	of	of	IN
cord-321013-8pkrg0mx	166	27	the	the	DT
cord-321013-8pkrg0mx	166	28	M	M	NNP
cord-321013-8pkrg0mx	166	29	protein	protein	NN
cord-321013-8pkrg0mx	166	30	appears	appear	VBZ
cord-321013-8pkrg0mx	166	31	to	to	TO
cord-321013-8pkrg0mx	166	32	be	be	VB
cord-321013-8pkrg0mx	166	33	lethal	lethal	JJ
cord-321013-8pkrg0mx	166	34	[	[	-LRB-
cord-321013-8pkrg0mx	166	35	83	83	CD
cord-321013-8pkrg0mx	166	36	]	]	-RRB-
cord-321013-8pkrg0mx	166	37	.	.	.
cord-321013-8pkrg0mx	167	1	Interestingly	interestingly	RB
cord-321013-8pkrg0mx	167	2	,	,	,
cord-321013-8pkrg0mx	167	3	N	N	NNP
cord-321013-8pkrg0mx	167	4	protein	protein	NN
cord-321013-8pkrg0mx	167	5	becomes	become	VBZ
cord-321013-8pkrg0mx	167	6	mutated	mutate	VBN
cord-321013-8pkrg0mx	167	7	in	in	IN
cord-321013-8pkrg0mx	167	8	its	-PRON-	PRP$
cord-321013-8pkrg0mx	167	9	CTD	CTD	NNP
cord-321013-8pkrg0mx	167	10	,	,	,
cord-321013-8pkrg0mx	167	11	and	and	CC
cord-321013-8pkrg0mx	167	12	these	these	DT
cord-321013-8pkrg0mx	167	13	changes	change	NNS
cord-321013-8pkrg0mx	167	14	then	then	RB
cord-321013-8pkrg0mx	167	15	compensate	compensate	VB
cord-321013-8pkrg0mx	167	16	for	for	IN
cord-321013-8pkrg0mx	167	17	the	the	DT
cord-321013-8pkrg0mx	167	18	loss	loss	NN
cord-321013-8pkrg0mx	167	19	of	of	IN
cord-321013-8pkrg0mx	167	20	the	the	DT
cord-321013-8pkrg0mx	167	21	two	two	CD
cord-321013-8pkrg0mx	167	22	M	M	NNP
cord-321013-8pkrg0mx	167	23	protein	protein	NN
cord-321013-8pkrg0mx	167	24	residues	residue	NNS
cord-321013-8pkrg0mx	167	25	,	,	,
cord-321013-8pkrg0mx	167	26	either	either	CC
cord-321013-8pkrg0mx	167	27	by	by	IN
cord-321013-8pkrg0mx	167	28	increasing	increase	VBG
cord-321013-8pkrg0mx	167	29	the	the	DT
cord-321013-8pkrg0mx	167	30	affinity	affinity	NN
cord-321013-8pkrg0mx	167	31	of	of	IN
cord-321013-8pkrg0mx	167	32	an	an	DT
cord-321013-8pkrg0mx	167	33	adjacent	adjacent	JJ
cord-321013-8pkrg0mx	167	34	interaction	interaction	NN
cord-321013-8pkrg0mx	167	35	or	or	CC
cord-321013-8pkrg0mx	167	36	by	by	IN
cord-321013-8pkrg0mx	167	37	providing	provide	VBG
cord-321013-8pkrg0mx	167	38	a	a	DT
cord-321013-8pkrg0mx	167	39	new	new	JJ
cord-321013-8pkrg0mx	167	40	contact	contact	NN
cord-321013-8pkrg0mx	167	41	point	point	NN
cord-321013-8pkrg0mx	167	42	between	between	IN
cord-321013-8pkrg0mx	167	43	N	N	NNP
cord-321013-8pkrg0mx	167	44	and	and	CC
cord-321013-8pkrg0mx	167	45	M	M	NNP
cord-321013-8pkrg0mx	167	46	to	to	TO
cord-321013-8pkrg0mx	167	47	stabilize	stabilize	VB
cord-321013-8pkrg0mx	167	48	the	the	DT
cord-321013-8pkrg0mx	167	49	virion	virion	NN
cord-321013-8pkrg0mx	167	50	[	[	-LRB-
cord-321013-8pkrg0mx	167	51	83	83	CD
cord-321013-8pkrg0mx	167	52	]	]	-RRB-
cord-321013-8pkrg0mx	167	53	.	.	.
cord-321013-8pkrg0mx	168	1	For	for	IN
cord-321013-8pkrg0mx	168	2	the	the	DT
cord-321013-8pkrg0mx	168	3	porcine	porcine	JJ
cord-321013-8pkrg0mx	168	4	transmissible	transmissible	JJ
cord-321013-8pkrg0mx	168	5	gastroenteritis	gastroenteritis	NN
cord-321013-8pkrg0mx	168	6	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	168	7	(	(	-LRB-
cord-321013-8pkrg0mx	168	8	TGEV	TGEV	NNP
cord-321013-8pkrg0mx	168	9	)	)	-RRB-
cord-321013-8pkrg0mx	168	10	,	,	,
cord-321013-8pkrg0mx	168	11	an	an	DT
cord-321013-8pkrg0mx	168	12	interaction	interaction	NN
cord-321013-8pkrg0mx	168	13	between	between	IN
cord-321013-8pkrg0mx	168	14	the	the	DT
cord-321013-8pkrg0mx	168	15	carboxy	carboxy	JJ
cord-321013-8pkrg0mx	168	16	terminus	terminus	NN
cord-321013-8pkrg0mx	168	17	of	of	IN
cord-321013-8pkrg0mx	168	18	M	M	NNP
cord-321013-8pkrg0mx	168	19	and	and	CC
cord-321013-8pkrg0mx	168	20	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	168	21	has	have	VBZ
cord-321013-8pkrg0mx	168	22	been	be	VBN
cord-321013-8pkrg0mx	168	23	mapped	map	VBN
cord-321013-8pkrg0mx	168	24	to	to	IN
cord-321013-8pkrg0mx	168	25	residues	residue	NNS
cord-321013-8pkrg0mx	168	26	233	233	CD
cord-321013-8pkrg0mx	168	27	-	-	SYM
cord-321013-8pkrg0mx	168	28	257	257	CD
cord-321013-8pkrg0mx	168	29	of	of	IN
cord-321013-8pkrg0mx	168	30	the	the	DT
cord-321013-8pkrg0mx	168	31	TGEV	TGEV	NNP
cord-321013-8pkrg0mx	168	32	M	M	NNP
cord-321013-8pkrg0mx	168	33	protein	protein	NN
cord-321013-8pkrg0mx	168	34	[	[	-LRB-
cord-321013-8pkrg0mx	168	35	82	82	CD
cord-321013-8pkrg0mx	168	36	]	]	-RRB-
cord-321013-8pkrg0mx	168	37	.	.	.
cord-321013-8pkrg0mx	169	1	This	this	DT
cord-321013-8pkrg0mx	169	2	segment	segment	NN
cord-321013-8pkrg0mx	169	3	corresponds	correspond	VBZ
cord-321013-8pkrg0mx	169	4	to	to	IN
cord-321013-8pkrg0mx	169	5	residues	residue	NNS
cord-321013-8pkrg0mx	169	6	201	201	CD
cord-321013-8pkrg0mx	169	7	-	-	SYM
cord-321013-8pkrg0mx	169	8	224	224	CD
cord-321013-8pkrg0mx	169	9	of	of	IN
cord-321013-8pkrg0mx	169	10	the	the	DT
cord-321013-8pkrg0mx	169	11	MHV	MHV	NNP
cord-321013-8pkrg0mx	169	12	M	M	NNP
cord-321013-8pkrg0mx	169	13	protein	protein	NN
cord-321013-8pkrg0mx	169	14	[	[	-LRB-
cord-321013-8pkrg0mx	169	15	83	83	CD
cord-321013-8pkrg0mx	169	16	]	]	-RRB-
cord-321013-8pkrg0mx	169	17	,	,	,
cord-321013-8pkrg0mx	169	18	which	which	WDT
cord-321013-8pkrg0mx	169	19	overlaps	overlap	VBZ
cord-321013-8pkrg0mx	169	20	with	with	IN
cord-321013-8pkrg0mx	169	21	only	only	RB
cord-321013-8pkrg0mx	169	22	one	one	CD
cord-321013-8pkrg0mx	169	23	of	of	IN
cord-321013-8pkrg0mx	169	24	the	the	DT
cord-321013-8pkrg0mx	169	25	critical	critical	JJ
cord-321013-8pkrg0mx	169	26	residues	residue	NNS
cord-321013-8pkrg0mx	169	27	identified	identify	VBN
cord-321013-8pkrg0mx	169	28	in	in	IN
cord-321013-8pkrg0mx	169	29	the	the	DT
cord-321013-8pkrg0mx	169	30	MHV	MHV	NNP
cord-321013-8pkrg0mx	169	31	M	M	NNP
cord-321013-8pkrg0mx	169	32	protein	protein	NN
cord-321013-8pkrg0mx	169	33	[	[	-LRB-
cord-321013-8pkrg0mx	169	34	61	61	CD
cord-321013-8pkrg0mx	169	35	]	]	-RRB-
cord-321013-8pkrg0mx	169	36	.	.	.
cord-321013-8pkrg0mx	170	1	This	this	DT
cord-321013-8pkrg0mx	170	2	region	region	NN
cord-321013-8pkrg0mx	170	3	of	of	IN
cord-321013-8pkrg0mx	170	4	the	the	DT
cord-321013-8pkrg0mx	170	5	two	two	CD
cord-321013-8pkrg0mx	170	6	M	M	NNP
cord-321013-8pkrg0mx	170	7	proteins	protein	NNS
cord-321013-8pkrg0mx	170	8	is	be	VBZ
cord-321013-8pkrg0mx	170	9	,	,	,
cord-321013-8pkrg0mx	170	10	however	however	RB
cord-321013-8pkrg0mx	170	11	,	,	,
cord-321013-8pkrg0mx	170	12	poorly	poorly	RB
cord-321013-8pkrg0mx	170	13	conserved	conserve	VBN
cord-321013-8pkrg0mx	170	14	and	and	CC
cord-321013-8pkrg0mx	170	15	the	the	DT
cord-321013-8pkrg0mx	170	16	apparent	apparent	JJ
cord-321013-8pkrg0mx	170	17	disagreement	disagreement	NN
cord-321013-8pkrg0mx	170	18	between	between	IN
cord-321013-8pkrg0mx	170	19	the	the	DT
cord-321013-8pkrg0mx	170	20	TGEV	TGEV	NNP
cord-321013-8pkrg0mx	170	21	and	and	CC
cord-321013-8pkrg0mx	170	22	MHV	MHV	NNP
cord-321013-8pkrg0mx	170	23	results	result	NNS
cord-321013-8pkrg0mx	170	24	may	may	MD
cord-321013-8pkrg0mx	170	25	relate	relate	VB
cord-321013-8pkrg0mx	170	26	to	to	IN
cord-321013-8pkrg0mx	170	27	differences	difference	NNS
cord-321013-8pkrg0mx	170	28	in	in	IN
cord-321013-8pkrg0mx	170	29	the	the	DT
cord-321013-8pkrg0mx	170	30	respective	respective	JJ
cord-321013-8pkrg0mx	170	31	folds	fold	NNS
cord-321013-8pkrg0mx	170	32	of	of	IN
cord-321013-8pkrg0mx	170	33	the	the	DT
cord-321013-8pkrg0mx	170	34	M	M	NNP
cord-321013-8pkrg0mx	170	35	proteins	protein	NNS
cord-321013-8pkrg0mx	170	36	,	,	,
cord-321013-8pkrg0mx	170	37	or	or	CC
cord-321013-8pkrg0mx	170	38	differences	difference	NNS
cord-321013-8pkrg0mx	170	39	in	in	IN
cord-321013-8pkrg0mx	170	40	how	how	WRB
cord-321013-8pkrg0mx	170	41	these	these	DT
cord-321013-8pkrg0mx	170	42	residues	residue	NNS
cord-321013-8pkrg0mx	170	43	influence	influence	VBP
cord-321013-8pkrg0mx	170	44	those	those	DT
cord-321013-8pkrg0mx	170	45	folds	fold	NNS
cord-321013-8pkrg0mx	170	46	[	[	-LRB-
cord-321013-8pkrg0mx	170	47	61	61	CD
cord-321013-8pkrg0mx	170	48	]	]	-RRB-
cord-321013-8pkrg0mx	170	49	.	.	.
cord-321013-8pkrg0mx	171	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	171	2	-	-	HYPH
cord-321013-8pkrg0mx	171	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	171	4	is	be	VBZ
cord-321013-8pkrg0mx	171	5	markedly	markedly	RB
cord-321013-8pkrg0mx	171	6	different	different	JJ
cord-321013-8pkrg0mx	171	7	from	from	IN
cord-321013-8pkrg0mx	171	8	other	other	JJ
cord-321013-8pkrg0mx	171	9	members	member	NNS
cord-321013-8pkrg0mx	171	10	of	of	IN
cord-321013-8pkrg0mx	171	11	the	the	DT
cord-321013-8pkrg0mx	171	12	Coronaviridae	Coronaviridae	NNP
cord-321013-8pkrg0mx	171	13	family	family	NN
cord-321013-8pkrg0mx	171	14	in	in	IN
cord-321013-8pkrg0mx	171	15	the	the	DT
cord-321013-8pkrg0mx	171	16	sense	sense	NN
cord-321013-8pkrg0mx	171	17	that	that	IN
cord-321013-8pkrg0mx	171	18	there	there	EX
cord-321013-8pkrg0mx	171	19	is	be	VBZ
cord-321013-8pkrg0mx	171	20	only	only	RB
cord-321013-8pkrg0mx	171	21	20%-30	20%-30	CD
cord-321013-8pkrg0mx	171	22	%	%	NN
cord-321013-8pkrg0mx	171	23	amino	amino	NN
cord-321013-8pkrg0mx	171	24	acid	acid	NN
cord-321013-8pkrg0mx	171	25	identity	identity	NN
cord-321013-8pkrg0mx	171	26	with	with	IN
cord-321013-8pkrg0mx	171	27	other	other	JJ
cord-321013-8pkrg0mx	171	28	known	know	VBN
cord-321013-8pkrg0mx	171	29	CoVs	CoVs	NNP
cord-321013-8pkrg0mx	171	30	,	,	,
cord-321013-8pkrg0mx	171	31	with	with	IN
cord-321013-8pkrg0mx	171	32	both	both	CC
cord-321013-8pkrg0mx	171	33	the	the	DT
cord-321013-8pkrg0mx	171	34	N	N	NNP
cord-321013-8pkrg0mx	171	35	and	and	CC
cord-321013-8pkrg0mx	171	36	M	M	NNP
cord-321013-8pkrg0mx	171	37	proteins	protein	NNS
cord-321013-8pkrg0mx	171	38	having	have	VBG
cord-321013-8pkrg0mx	171	39	low	low	JJ
cord-321013-8pkrg0mx	171	40	sequence	sequence	NN
cord-321013-8pkrg0mx	171	41	homology	homology	NN
cord-321013-8pkrg0mx	171	42	[	[	-LRB-
cord-321013-8pkrg0mx	171	43	76	76	CD
cord-321013-8pkrg0mx	171	44	,	,	,
cord-321013-8pkrg0mx	171	45	101	101	CD
cord-321013-8pkrg0mx	171	46	]	]	-RRB-
cord-321013-8pkrg0mx	171	47	.	.	.
cord-321013-8pkrg0mx	172	1	One	one	PRP
cord-321013-8pkrg0mx	172	2	might	may	MD
cord-321013-8pkrg0mx	172	3	therefore	therefore	RB
cord-321013-8pkrg0mx	172	4	expect	expect	VB
cord-321013-8pkrg0mx	172	5	that	that	IN
cord-321013-8pkrg0mx	172	6	there	there	EX
cord-321013-8pkrg0mx	172	7	could	could	MD
cord-321013-8pkrg0mx	172	8	be	be	VB
cord-321013-8pkrg0mx	172	9	differences	difference	NNS
cord-321013-8pkrg0mx	172	10	in	in	IN
cord-321013-8pkrg0mx	172	11	the	the	DT
cord-321013-8pkrg0mx	172	12	mechanism	mechanism	NN
cord-321013-8pkrg0mx	172	13	of	of	IN
cord-321013-8pkrg0mx	172	14	viral	viral	JJ
cord-321013-8pkrg0mx	172	15	assembly	assembly	NN
cord-321013-8pkrg0mx	172	16	.	.	.
cord-321013-8pkrg0mx	173	1	A	a	DT
cord-321013-8pkrg0mx	173	2	mammalian	mammalian	JJ
cord-321013-8pkrg0mx	173	3	two	two	CD
cord-321013-8pkrg0mx	173	4	-	-	HYPH
cord-321013-8pkrg0mx	173	5	hybrid	hybrid	NN
cord-321013-8pkrg0mx	173	6	system	system	NN
cord-321013-8pkrg0mx	173	7	,	,	,
cord-321013-8pkrg0mx	173	8	which	which	WDT
cord-321013-8pkrg0mx	173	9	is	be	VBZ
cord-321013-8pkrg0mx	173	10	performed	perform	VBN
cord-321013-8pkrg0mx	173	11	in	in	IN
cord-321013-8pkrg0mx	173	12	vivo	vivo	NN
cord-321013-8pkrg0mx	173	13	so	so	IN
cord-321013-8pkrg0mx	173	14	that	that	IN
cord-321013-8pkrg0mx	173	15	viral	viral	JJ
cord-321013-8pkrg0mx	173	16	proteins	protein	NNS
cord-321013-8pkrg0mx	173	17	will	will	MD
cord-321013-8pkrg0mx	173	18	adopt	adopt	VB
cord-321013-8pkrg0mx	173	19	their	-PRON-	PRP$
cord-321013-8pkrg0mx	173	20	native	native	JJ
cord-321013-8pkrg0mx	173	21	state	state	NN
cord-321013-8pkrg0mx	173	22	and	and	CC
cord-321013-8pkrg0mx	173	23	therefore	therefore	RB
cord-321013-8pkrg0mx	173	24	be	be	VBP
cord-321013-8pkrg0mx	173	25	more	more	RBR
cord-321013-8pkrg0mx	173	26	likely	likely	JJ
cord-321013-8pkrg0mx	173	27	to	to	TO
cord-321013-8pkrg0mx	173	28	interact	interact	VB
cord-321013-8pkrg0mx	173	29	in	in	IN
cord-321013-8pkrg0mx	173	30	a	a	DT
cord-321013-8pkrg0mx	173	31	biologically	biologically	RB
cord-321013-8pkrg0mx	173	32	accurate	accurate	JJ
cord-321013-8pkrg0mx	173	33	manner	manner	NN
cord-321013-8pkrg0mx	173	34	[	[	-LRB-
cord-321013-8pkrg0mx	173	35	102	102	CD
cord-321013-8pkrg0mx	173	36	]	]	-RRB-
cord-321013-8pkrg0mx	173	37	,	,	,
cord-321013-8pkrg0mx	173	38	confirmed	confirm	VBD
cord-321013-8pkrg0mx	173	39	that	that	IN
cord-321013-8pkrg0mx	173	40	N	N	NNP
cord-321013-8pkrg0mx	173	41	-	-	HYPH
cord-321013-8pkrg0mx	173	42	M	M	NNP
cord-321013-8pkrg0mx	173	43	protein	protein	NN
cord-321013-8pkrg0mx	173	44	interactions	interaction	NNS
cord-321013-8pkrg0mx	173	45	occur	occur	VBP
cord-321013-8pkrg0mx	173	46	in	in	IN
cord-321013-8pkrg0mx	173	47	vivo	vivo	NNP
cord-321013-8pkrg0mx	173	48	[	[	-LRB-
cord-321013-8pkrg0mx	173	49	66	66	CD
cord-321013-8pkrg0mx	173	50	]	]	-RRB-
cord-321013-8pkrg0mx	173	51	.	.	.
cord-321013-8pkrg0mx	174	1	Moreover	moreover	RB
cord-321013-8pkrg0mx	174	2	,	,	,
cord-321013-8pkrg0mx	174	3	this	this	DT
cord-321013-8pkrg0mx	174	4	study	study	NN
cord-321013-8pkrg0mx	174	5	identified	identify	VBD
cord-321013-8pkrg0mx	174	6	a	a	DT
cord-321013-8pkrg0mx	174	7	stretch	stretch	NN
cord-321013-8pkrg0mx	174	8	of	of	IN
cord-321013-8pkrg0mx	174	9	amino	amino	JJ
cord-321013-8pkrg0mx	174	10	acids	acid	NNS
cord-321013-8pkrg0mx	174	11	in	in	IN
cord-321013-8pkrg0mx	174	12	the	the	DT
cord-321013-8pkrg0mx	174	13	middle	middle	NN
cord-321013-8pkrg0mx	174	14	of	of	IN
cord-321013-8pkrg0mx	174	15	the	the	DT
cord-321013-8pkrg0mx	174	16	N	n	CD
cord-321013-8pkrg0mx	174	17	gene	gene	NN
cord-321013-8pkrg0mx	174	18	that	that	WDT
cord-321013-8pkrg0mx	174	19	may	may	MD
cord-321013-8pkrg0mx	174	20	be	be	VB
cord-321013-8pkrg0mx	174	21	critical	critical	JJ
cord-321013-8pkrg0mx	174	22	for	for	IN
cord-321013-8pkrg0mx	174	23	N	N	NNP
cord-321013-8pkrg0mx	174	24	-	-	HYPH
cord-321013-8pkrg0mx	174	25	M	M	NNP
cord-321013-8pkrg0mx	174	26	protein	protein	NN
cord-321013-8pkrg0mx	174	27	interaction	interaction	NN
cord-321013-8pkrg0mx	174	28	[	[	-LRB-
cord-321013-8pkrg0mx	174	29	66	66	CD
cord-321013-8pkrg0mx	174	30	]	]	-RRB-
cord-321013-8pkrg0mx	174	31	.	.	.
cord-321013-8pkrg0mx	175	1	This	this	DT
cord-321013-8pkrg0mx	175	2	stretch	stretch	NN
cord-321013-8pkrg0mx	175	3	of	of	IN
cord-321013-8pkrg0mx	175	4	amino	amino	JJ
cord-321013-8pkrg0mx	175	5	acids	acid	NNS
cord-321013-8pkrg0mx	175	6	spans	span	VBZ
cord-321013-8pkrg0mx	175	7	the	the	DT
cord-321013-8pkrg0mx	175	8	LKR	LKR	NNP
cord-321013-8pkrg0mx	175	9	and	and	CC
cord-321013-8pkrg0mx	175	10	dimerization	dimerization	NN
cord-321013-8pkrg0mx	175	11	domain	domain	NN
cord-321013-8pkrg0mx	175	12	in	in	IN
cord-321013-8pkrg0mx	175	13	the	the	DT
cord-321013-8pkrg0mx	175	14	CTD	CTD	NNP
cord-321013-8pkrg0mx	175	15	,	,	,
cord-321013-8pkrg0mx	175	16	suggesting	suggest	VBG
cord-321013-8pkrg0mx	175	17	that	that	IN
cord-321013-8pkrg0mx	175	18	this	this	DT
cord-321013-8pkrg0mx	175	19	region	region	NN
cord-321013-8pkrg0mx	175	20	may	may	MD
cord-321013-8pkrg0mx	175	21	be	be	VB
cord-321013-8pkrg0mx	175	22	essential	essential	JJ
cord-321013-8pkrg0mx	175	23	in	in	IN
cord-321013-8pkrg0mx	175	24	maintaining	maintain	VBG
cord-321013-8pkrg0mx	175	25	correct	correct	JJ
cord-321013-8pkrg0mx	175	26	N	N	NNP
cord-321013-8pkrg0mx	175	27	protein	protein	NN
cord-321013-8pkrg0mx	175	28	conformation	conformation	NN
cord-321013-8pkrg0mx	175	29	for	for	IN
cord-321013-8pkrg0mx	175	30	both	both	DT
cord-321013-8pkrg0mx	175	31	self	self	NN
cord-321013-8pkrg0mx	175	32	-	-	HYPH
cord-321013-8pkrg0mx	175	33	association	association	NN
cord-321013-8pkrg0mx	175	34	and	and	CC
cord-321013-8pkrg0mx	175	35	N	N	NNP
cord-321013-8pkrg0mx	175	36	-	-	HYPH
cord-321013-8pkrg0mx	175	37	M	M	NNP
cord-321013-8pkrg0mx	175	38	protein	protein	NN
cord-321013-8pkrg0mx	175	39	interaction	interaction	NN
cord-321013-8pkrg0mx	175	40	[	[	-LRB-
cord-321013-8pkrg0mx	175	41	66	66	CD
cord-321013-8pkrg0mx	175	42	]	]	-RRB-
cord-321013-8pkrg0mx	175	43	.	.	.
cord-321013-8pkrg0mx	176	1	Despite	despite	IN
cord-321013-8pkrg0mx	176	2	SARS	SARS	NNP
cord-321013-8pkrg0mx	176	3	-	-	HYPH
cord-321013-8pkrg0mx	176	4	CoV	CoV	NNP
cord-321013-8pkrg0mx	176	5	having	have	VBG
cord-321013-8pkrg0mx	176	6	the	the	DT
cord-321013-8pkrg0mx	176	7	closest	close	JJS
cord-321013-8pkrg0mx	176	8	genetic	genetic	JJ
cord-321013-8pkrg0mx	176	9	resemblance	resemblance	NN
cord-321013-8pkrg0mx	176	10	to	to	IN
cord-321013-8pkrg0mx	176	11	MHV	MHV	NNP
cord-321013-8pkrg0mx	176	12	,	,	,
cord-321013-8pkrg0mx	176	13	the	the	DT
cord-321013-8pkrg0mx	176	14	M	M	NNP
cord-321013-8pkrg0mx	176	15	proteins	protein	NNS
cord-321013-8pkrg0mx	176	16	of	of	IN
cord-321013-8pkrg0mx	176	17	these	these	DT
cord-321013-8pkrg0mx	176	18	viruses	virus	NNS
cord-321013-8pkrg0mx	176	19	bind	bind	VBP
cord-321013-8pkrg0mx	176	20	to	to	IN
cord-321013-8pkrg0mx	176	21	different	different	JJ
cord-321013-8pkrg0mx	176	22	domains	domain	NNS
cord-321013-8pkrg0mx	176	23	on	on	IN
cord-321013-8pkrg0mx	176	24	the	the	DT
cord-321013-8pkrg0mx	176	25	N	n	CD
cord-321013-8pkrg0mx	176	26	protein	protein	NN
cord-321013-8pkrg0mx	176	27	.	.	.
cord-321013-8pkrg0mx	177	1	CoVs	CoVs	NNP
cord-321013-8pkrg0mx	177	2	assemble	assemble	VB
cord-321013-8pkrg0mx	177	3	and	and	CC
cord-321013-8pkrg0mx	177	4	bud	bud	NN
cord-321013-8pkrg0mx	177	5	intracellularly	intracellularly	RB
cord-321013-8pkrg0mx	177	6	at	at	IN
cord-321013-8pkrg0mx	177	7	the	the	DT
cord-321013-8pkrg0mx	177	8	ER	ER	NNP
cord-321013-8pkrg0mx	177	9	-	-	HYPH
cord-321013-8pkrg0mx	177	10	Golgi	Golgi	NNP
cord-321013-8pkrg0mx	177	11	complex	complex	NN
cord-321013-8pkrg0mx	177	12	[	[	-LRB-
cord-321013-8pkrg0mx	177	13	96	96	CD
cord-321013-8pkrg0mx	177	14	,	,	,
cord-321013-8pkrg0mx	177	15	103	103	CD
cord-321013-8pkrg0mx	177	16	]	]	-RRB-
cord-321013-8pkrg0mx	177	17	,	,	,
cord-321013-8pkrg0mx	177	18	and	and	CC
cord-321013-8pkrg0mx	177	19	association	association	NN
cord-321013-8pkrg0mx	177	20	of	of	IN
cord-321013-8pkrg0mx	177	21	the	the	DT
cord-321013-8pkrg0mx	177	22	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	177	23	with	with	IN
cord-321013-8pkrg0mx	177	24	this	this	DT
cord-321013-8pkrg0mx	177	25	organelle	organelle	NN
cord-321013-8pkrg0mx	177	26	may	may	MD
cord-321013-8pkrg0mx	177	27	reflect	reflect	VB
cord-321013-8pkrg0mx	177	28	a	a	DT
cord-321013-8pkrg0mx	177	29	role	role	NN
cord-321013-8pkrg0mx	177	30	in	in	IN
cord-321013-8pkrg0mx	177	31	virus	virus	NN
cord-321013-8pkrg0mx	177	32	budding	bud	VBG
cord-321013-8pkrg0mx	177	33	.	.	.
cord-321013-8pkrg0mx	178	1	The	the	DT
cord-321013-8pkrg0mx	178	2	formation	formation	NN
cord-321013-8pkrg0mx	178	3	of	of	IN
cord-321013-8pkrg0mx	178	4	the	the	DT
cord-321013-8pkrg0mx	178	5	virion	virion	NN
cord-321013-8pkrg0mx	178	6	envelope	envelope	NN
cord-321013-8pkrg0mx	178	7	requires	require	VBZ
cord-321013-8pkrg0mx	178	8	expression	expression	NN
cord-321013-8pkrg0mx	178	9	of	of	IN
cord-321013-8pkrg0mx	178	10	only	only	JJ
cord-321013-8pkrg0mx	178	11	M	M	NNP
cord-321013-8pkrg0mx	178	12	-	-	HYPH
cord-321013-8pkrg0mx	178	13	and	and	CC
cord-321013-8pkrg0mx	178	14	E	e	NN
cord-321013-8pkrg0mx	178	15	-	-	NN
cord-321013-8pkrg0mx	178	16	protein	protein	NN
cord-321013-8pkrg0mx	178	17	,	,	,
cord-321013-8pkrg0mx	178	18	and	and	CC
cord-321013-8pkrg0mx	178	19	not	not	RB
cord-321013-8pkrg0mx	178	20	N	n	NN
cord-321013-8pkrg0mx	178	21	protein	protein	NN
cord-321013-8pkrg0mx	178	22	,	,	,
cord-321013-8pkrg0mx	178	23	as	as	IN
cord-321013-8pkrg0mx	178	24	has	have	VBZ
cord-321013-8pkrg0mx	178	25	been	be	VBN
cord-321013-8pkrg0mx	178	26	observed	observe	VBN
cord-321013-8pkrg0mx	178	27	for	for	IN
cord-321013-8pkrg0mx	178	28	MHV	mhv	NN
cord-321013-8pkrg0mx	178	29	[	[	-LRB-
cord-321013-8pkrg0mx	178	30	104	104	CD
cord-321013-8pkrg0mx	178	31	]	]	-RRB-
cord-321013-8pkrg0mx	178	32	,	,	,
cord-321013-8pkrg0mx	178	33	IBV	IBV	NNP
cord-321013-8pkrg0mx	178	34	[	[	-LRB-
cord-321013-8pkrg0mx	178	35	105	105	CD
cord-321013-8pkrg0mx	178	36	]	]	-RRB-
cord-321013-8pkrg0mx	178	37	,	,	.
cord-321013-8pkrg0mx	179	1	TGEV	TGEV	NNP
cord-321013-8pkrg0mx	179	2	[	[	-LRB-
cord-321013-8pkrg0mx	179	3	106	106	CD
cord-321013-8pkrg0mx	179	4	]	]	-RRB-
cord-321013-8pkrg0mx	179	5	,	,	,
cord-321013-8pkrg0mx	179	6	and	and	CC
cord-321013-8pkrg0mx	179	7	BCoV	BCoV	NNP
cord-321013-8pkrg0mx	179	8	[	[	-LRB-
cord-321013-8pkrg0mx	179	9	107	107	CD
cord-321013-8pkrg0mx	179	10	]	]	-RRB-
cord-321013-8pkrg0mx	179	11	.	.	.
cord-321013-8pkrg0mx	180	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	180	2	was	be	VBD
cord-321013-8pkrg0mx	180	3	recently	recently	RB
cord-321013-8pkrg0mx	180	4	noted	note	VBN
cord-321013-8pkrg0mx	180	5	however	however	RB
cord-321013-8pkrg0mx	180	6	,	,	,
cord-321013-8pkrg0mx	180	7	that	that	IN
cord-321013-8pkrg0mx	180	8	these	these	DT
cord-321013-8pkrg0mx	180	9	studies	study	NNS
cord-321013-8pkrg0mx	180	10	all	all	DT
cord-321013-8pkrg0mx	180	11	used	use	VBD
cord-321013-8pkrg0mx	180	12	vaccinia	vaccinia	NN
cord-321013-8pkrg0mx	180	13	-	-	HYPH
cord-321013-8pkrg0mx	180	14	based	base	VBN
cord-321013-8pkrg0mx	180	15	expression	expression	NN
cord-321013-8pkrg0mx	180	16	systems	system	NNS
cord-321013-8pkrg0mx	180	17	,	,	,
cord-321013-8pkrg0mx	180	18	where	where	WRB
cord-321013-8pkrg0mx	180	19	overexpression	overexpression	NN
cord-321013-8pkrg0mx	180	20	of	of	IN
cord-321013-8pkrg0mx	180	21	viral	viral	JJ
cord-321013-8pkrg0mx	180	22	membrane	membrane	NN
cord-321013-8pkrg0mx	180	23	proteins	protein	NNS
cord-321013-8pkrg0mx	180	24	may	may	MD
cord-321013-8pkrg0mx	180	25	lead	lead	VB
cord-321013-8pkrg0mx	180	26	to	to	TO
cord-321013-8pkrg0mx	180	27	release	release	VB
cord-321013-8pkrg0mx	180	28	in	in	IN
cord-321013-8pkrg0mx	180	29	microvesicles	microvesicle	NNS
cord-321013-8pkrg0mx	180	30	,	,	,
cord-321013-8pkrg0mx	180	31	complicating	complicate	VBG
cord-321013-8pkrg0mx	180	32	the	the	DT
cord-321013-8pkrg0mx	180	33	interpretation	interpretation	NN
cord-321013-8pkrg0mx	180	34	of	of	IN
cord-321013-8pkrg0mx	180	35	virus	virus	NN
cord-321013-8pkrg0mx	180	36	-	-	HYPH
cord-321013-8pkrg0mx	180	37	like	like	JJ
cord-321013-8pkrg0mx	180	38	particle	particle	NN
cord-321013-8pkrg0mx	180	39	(	(	-LRB-
cord-321013-8pkrg0mx	180	40	VLP	VLP	NNP
cord-321013-8pkrg0mx	180	41	)	)	-RRB-
cord-321013-8pkrg0mx	180	42	experiments	experiment	NNS
cord-321013-8pkrg0mx	180	43	[	[	-LRB-
cord-321013-8pkrg0mx	180	44	108	108	CD
cord-321013-8pkrg0mx	180	45	]	]	-RRB-
cord-321013-8pkrg0mx	180	46	.	.	.
cord-321013-8pkrg0mx	181	1	Subsequent	subsequent	JJ
cord-321013-8pkrg0mx	181	2	experiments	experiment	NNS
cord-321013-8pkrg0mx	181	3	using	use	VBG
cord-321013-8pkrg0mx	181	4	transient	transient	JJ
cord-321013-8pkrg0mx	181	5	transfection	transfection	NN
cord-321013-8pkrg0mx	181	6	to	to	TO
cord-321013-8pkrg0mx	181	7	express	express	VB
cord-321013-8pkrg0mx	181	8	the	the	DT
cord-321013-8pkrg0mx	181	9	proteins	protein	NNS
cord-321013-8pkrg0mx	181	10	from	from	IN
cord-321013-8pkrg0mx	181	11	plasmids	plasmid	NNS
cord-321013-8pkrg0mx	181	12	have	have	VBP
cord-321013-8pkrg0mx	181	13	shown	show	VBN
cord-321013-8pkrg0mx	181	14	that	that	IN
cord-321013-8pkrg0mx	181	15	,	,	,
cord-321013-8pkrg0mx	181	16	at	at	IN
cord-321013-8pkrg0mx	181	17	least	least	JJS
cord-321013-8pkrg0mx	181	18	for	for	IN
cord-321013-8pkrg0mx	181	19	MHV	MHV	NNP
cord-321013-8pkrg0mx	181	20	[	[	-LRB-
cord-321013-8pkrg0mx	181	21	109	109	CD
cord-321013-8pkrg0mx	181	22	]	]	-RRB-
cord-321013-8pkrg0mx	181	23	,	,	,
cord-321013-8pkrg0mx	181	24	SARS	SARS	NNP
cord-321013-8pkrg0mx	181	25	-	-	HYPH
cord-321013-8pkrg0mx	181	26	CoV	CoV	NNP
cord-321013-8pkrg0mx	181	27	[	[	-LRB-
cord-321013-8pkrg0mx	181	28	110	110	CD
cord-321013-8pkrg0mx	181	29	]	]	-RRB-
cord-321013-8pkrg0mx	181	30	and	and	CC
cord-321013-8pkrg0mx	181	31	IBV	IBV	NNP
cord-321013-8pkrg0mx	181	32	[	[	-LRB-
cord-321013-8pkrg0mx	181	33	111	111	CD
cord-321013-8pkrg0mx	181	34	]	]	-RRB-
cord-321013-8pkrg0mx	181	35	,	,	,
cord-321013-8pkrg0mx	181	36	the	the	DT
cord-321013-8pkrg0mx	181	37	presence	presence	NN
cord-321013-8pkrg0mx	181	38	of	of	IN
cord-321013-8pkrg0mx	181	39	N	n	CD
cord-321013-8pkrg0mx	181	40	protein	protein	NN
cord-321013-8pkrg0mx	181	41	can	can	MD
cord-321013-8pkrg0mx	181	42	greatly	greatly	RB
cord-321013-8pkrg0mx	181	43	increase	increase	VB
cord-321013-8pkrg0mx	181	44	VLP	VLP	NNP
cord-321013-8pkrg0mx	181	45	yield	yield	NN
cord-321013-8pkrg0mx	181	46	.	.	.
cord-321013-8pkrg0mx	182	1	Therefore	therefore	RB
cord-321013-8pkrg0mx	182	2	,	,	,
cord-321013-8pkrg0mx	182	3	while	while	IN
cord-321013-8pkrg0mx	182	4	N	n	CD
cord-321013-8pkrg0mx	182	5	protein	protein	NN
cord-321013-8pkrg0mx	182	6	is	be	VBZ
cord-321013-8pkrg0mx	182	7	not	not	RB
cord-321013-8pkrg0mx	182	8	necessarily	necessarily	RB
cord-321013-8pkrg0mx	182	9	required	require	VBN
cord-321013-8pkrg0mx	182	10	for	for	IN
cord-321013-8pkrg0mx	182	11	envelope	envelope	NN
cord-321013-8pkrg0mx	182	12	formation	formation	NN
cord-321013-8pkrg0mx	182	13	,	,	,
cord-321013-8pkrg0mx	182	14	N	N	NNP
cord-321013-8pkrg0mx	182	15	protein	protein	NN
cord-321013-8pkrg0mx	182	16	plays	play	VBZ
cord-321013-8pkrg0mx	182	17	an	an	DT
cord-321013-8pkrg0mx	182	18	important	important	JJ
cord-321013-8pkrg0mx	182	19	role	role	NN
cord-321013-8pkrg0mx	182	20	in	in	IN
cord-321013-8pkrg0mx	182	21	forming	form	VBG
cord-321013-8pkrg0mx	182	22	a	a	DT
cord-321013-8pkrg0mx	182	23	complete	complete	JJ
cord-321013-8pkrg0mx	182	24	virion	virion	NN
cord-321013-8pkrg0mx	182	25	[	[	-LRB-
cord-321013-8pkrg0mx	182	26	108	108	CD
cord-321013-8pkrg0mx	182	27	]	]	-RRB-
cord-321013-8pkrg0mx	182	28	.	.	.
cord-321013-8pkrg0mx	183	1	N	n	NN
cord-321013-8pkrg0mx	183	2	protein	protein	NN
cord-321013-8pkrg0mx	183	3	binds	bind	VBZ
cord-321013-8pkrg0mx	183	4	to	to	IN
cord-321013-8pkrg0mx	183	5	both	both	CC
cord-321013-8pkrg0mx	183	6	full	full	JJ
cord-321013-8pkrg0mx	183	7	-	-	HYPH
cord-321013-8pkrg0mx	183	8	length	length	NN
cord-321013-8pkrg0mx	183	9	genomic	genomic	JJ
cord-321013-8pkrg0mx	183	10	RNA	RNA	NNP
cord-321013-8pkrg0mx	183	11	(	(	-LRB-
cord-321013-8pkrg0mx	183	12	gRNA	gRNA	NNP
cord-321013-8pkrg0mx	183	13	)	)	-RRB-
cord-321013-8pkrg0mx	183	14	as	as	RB
cord-321013-8pkrg0mx	183	15	well	well	RB
cord-321013-8pkrg0mx	183	16	as	as	IN
cord-321013-8pkrg0mx	183	17	all	all	DT
cord-321013-8pkrg0mx	183	18	six	six	CD
cord-321013-8pkrg0mx	183	19	sgRNAs	sgrna	NNS
cord-321013-8pkrg0mx	183	20	but	but	CC
cord-321013-8pkrg0mx	183	21	displays	display	VBZ
cord-321013-8pkrg0mx	183	22	an	an	DT
cord-321013-8pkrg0mx	183	23	increased	increase	VBN
cord-321013-8pkrg0mx	183	24	affinity	affinity	NN
cord-321013-8pkrg0mx	183	25	for	for	IN
cord-321013-8pkrg0mx	183	26	gRNA	gRNA	NNS
cord-321013-8pkrg0mx	183	27	[	[	-LRB-
cord-321013-8pkrg0mx	183	28	112	112	CD
cord-321013-8pkrg0mx	183	29	]	]	-RRB-
cord-321013-8pkrg0mx	183	30	.	.	.
cord-321013-8pkrg0mx	184	1	The	the	DT
cord-321013-8pkrg0mx	184	2	gRNA	gRNA	NNS
cord-321013-8pkrg0mx	184	3	functions	function	NNS
cord-321013-8pkrg0mx	184	4	as	as	IN
cord-321013-8pkrg0mx	184	5	a	a	DT
cord-321013-8pkrg0mx	184	6	template	template	NN
cord-321013-8pkrg0mx	184	7	for	for	IN
cord-321013-8pkrg0mx	184	8	the	the	DT
cord-321013-8pkrg0mx	184	9	viral	viral	JJ
cord-321013-8pkrg0mx	184	10	RNA	RNA	NNP
cord-321013-8pkrg0mx	184	11	-	-	HYPH
cord-321013-8pkrg0mx	184	12	dependent	dependent	JJ
cord-321013-8pkrg0mx	184	13	RNA	RNA	NNP
cord-321013-8pkrg0mx	184	14	polymerase	polymerase	NN
cord-321013-8pkrg0mx	184	15	as	as	RB
cord-321013-8pkrg0mx	184	16	well	well	RB
cord-321013-8pkrg0mx	184	17	as	as	IN
cord-321013-8pkrg0mx	184	18	a	a	DT
cord-321013-8pkrg0mx	184	19	message	message	NN
cord-321013-8pkrg0mx	184	20	for	for	IN
cord-321013-8pkrg0mx	184	21	translation	translation	NN
cord-321013-8pkrg0mx	184	22	[	[	-LRB-
cord-321013-8pkrg0mx	184	23	52	52	CD
cord-321013-8pkrg0mx	184	24	]	]	-RRB-
cord-321013-8pkrg0mx	184	25	.	.	.
cord-321013-8pkrg0mx	185	1	During	during	IN
cord-321013-8pkrg0mx	185	2	infection	infection	NN
cord-321013-8pkrg0mx	185	3	,	,	,
cord-321013-8pkrg0mx	185	4	gRNA	gRNA	''
cord-321013-8pkrg0mx	185	5	is	be	VBZ
cord-321013-8pkrg0mx	185	6	initially	initially	RB
cord-321013-8pkrg0mx	185	7	transcribed	transcribe	VBN
cord-321013-8pkrg0mx	185	8	by	by	IN
cord-321013-8pkrg0mx	185	9	an	an	DT
cord-321013-8pkrg0mx	185	10	early	early	JJ
cord-321013-8pkrg0mx	185	11	polymerase	polymerase	NN
cord-321013-8pkrg0mx	185	12	activity	activity	NN
cord-321013-8pkrg0mx	185	13	into	into	IN
cord-321013-8pkrg0mx	185	14	a	a	DT
cord-321013-8pkrg0mx	185	15	genome	genome	NN
cord-321013-8pkrg0mx	185	16	-	-	HYPH
cord-321013-8pkrg0mx	185	17	sized	sized	JJ
cord-321013-8pkrg0mx	185	18	negative	negative	JJ
cord-321013-8pkrg0mx	185	19	-	-	HYPH
cord-321013-8pkrg0mx	185	20	stranded	strand	VBN
cord-321013-8pkrg0mx	185	21	RNA	RNA	NNP
cord-321013-8pkrg0mx	185	22	[	[	-LRB-
cord-321013-8pkrg0mx	185	23	113	113	CD
cord-321013-8pkrg0mx	185	24	]	]	-RRB-
cord-321013-8pkrg0mx	185	25	and	and	CC
cord-321013-8pkrg0mx	185	26	then	then	RB
cord-321013-8pkrg0mx	185	27	a	a	DT
cord-321013-8pkrg0mx	185	28	late	late	JJ
cord-321013-8pkrg0mx	185	29	polymerase	polymerase	NN
cord-321013-8pkrg0mx	185	30	activity	activity	NN
cord-321013-8pkrg0mx	185	31	transcribes	transcribe	VBZ
cord-321013-8pkrg0mx	185	32	the	the	DT
cord-321013-8pkrg0mx	185	33	negative	negative	NN
cord-321013-8pkrg0mx	185	34	-	-	HYPH
cord-321013-8pkrg0mx	185	35	stranded	strand	VBN
cord-321013-8pkrg0mx	185	36	RNA	RNA	NNP
cord-321013-8pkrg0mx	185	37	into	into	IN
cord-321013-8pkrg0mx	185	38	a	a	DT
cord-321013-8pkrg0mx	185	39	full	full	JJ
cord-321013-8pkrg0mx	185	40	length	length	NN
cord-321013-8pkrg0mx	185	41	gRNA	gRNA	NNS
cord-321013-8pkrg0mx	185	42	that	that	WDT
cord-321013-8pkrg0mx	185	43	is	be	VBZ
cord-321013-8pkrg0mx	185	44	bound	bind	VBN
cord-321013-8pkrg0mx	185	45	to	to	IN
cord-321013-8pkrg0mx	185	46	polysomes	polysomes	NNP
cord-321013-8pkrg0mx	185	47	[	[	-LRB-
cord-321013-8pkrg0mx	185	48	113	113	CD
cord-321013-8pkrg0mx	185	49	]	]	-RRB-
cord-321013-8pkrg0mx	185	50	and	and	CC
cord-321013-8pkrg0mx	185	51	detected	detect	VBN
cord-321013-8pkrg0mx	185	52	in	in	IN
cord-321013-8pkrg0mx	185	53	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	185	54	structures	structure	NNS
cord-321013-8pkrg0mx	185	55	[	[	-LRB-
cord-321013-8pkrg0mx	185	56	114	114	CD
cord-321013-8pkrg0mx	185	57	]	]	-RRB-
cord-321013-8pkrg0mx	185	58	.	.	.
cord-321013-8pkrg0mx	186	1	Numerous	numerous	JJ
cord-321013-8pkrg0mx	186	2	studies	study	NNS
cord-321013-8pkrg0mx	186	3	have	have	VBP
cord-321013-8pkrg0mx	186	4	demonstrated	demonstrate	VBN
cord-321013-8pkrg0mx	186	5	that	that	IN
cord-321013-8pkrg0mx	186	6	N	n	CD
cord-321013-8pkrg0mx	186	7	protein	protein	NN
cord-321013-8pkrg0mx	186	8	is	be	VBZ
cord-321013-8pkrg0mx	186	9	required	require	VBN
cord-321013-8pkrg0mx	186	10	for	for	IN
cord-321013-8pkrg0mx	186	11	optimal	optimal	JJ
cord-321013-8pkrg0mx	186	12	CoV	cov	NN
cord-321013-8pkrg0mx	186	13	replication	replication	NN
cord-321013-8pkrg0mx	186	14	[	[	-LRB-
cord-321013-8pkrg0mx	186	15	31	31	CD
cord-321013-8pkrg0mx	186	16	,	,	,
cord-321013-8pkrg0mx	186	17	[	[	-LRB-
cord-321013-8pkrg0mx	186	18	115	115	CD
cord-321013-8pkrg0mx	186	19	]	]	-RRB-
cord-321013-8pkrg0mx	186	20	[	[	-LRB-
cord-321013-8pkrg0mx	186	21	116	116	CD
cord-321013-8pkrg0mx	186	22	]	]	-RRB-
cord-321013-8pkrg0mx	186	23	[	[	-LRB-
cord-321013-8pkrg0mx	186	24	117	117	CD
cord-321013-8pkrg0mx	186	25	]	]	-RRB-
cord-321013-8pkrg0mx	186	26	[	[	-LRB-
cord-321013-8pkrg0mx	186	27	118	118	CD
cord-321013-8pkrg0mx	186	28	]	]	-RRB-
cord-321013-8pkrg0mx	186	29	[	[	-LRB-
cord-321013-8pkrg0mx	186	30	119	119	CD
cord-321013-8pkrg0mx	186	31	]	]	-RRB-
cord-321013-8pkrg0mx	186	32	[	[	-LRB-
cord-321013-8pkrg0mx	186	33	120	120	CD
cord-321013-8pkrg0mx	186	34	]	]	-RRB-
cord-321013-8pkrg0mx	186	35	[	[	-LRB-
cord-321013-8pkrg0mx	186	36	121	121	CD
cord-321013-8pkrg0mx	186	37	]	]	-RRB-
cord-321013-8pkrg0mx	186	38	.	.	.
cord-321013-8pkrg0mx	187	1	The	the	DT
cord-321013-8pkrg0mx	187	2	participation	participation	NN
cord-321013-8pkrg0mx	187	3	of	of	IN
cord-321013-8pkrg0mx	187	4	N	n	CD
cord-321013-8pkrg0mx	187	5	protein	protein	NN
cord-321013-8pkrg0mx	187	6	in	in	IN
cord-321013-8pkrg0mx	187	7	an	an	DT
cord-321013-8pkrg0mx	187	8	early	early	JJ
cord-321013-8pkrg0mx	187	9	event	event	NN
cord-321013-8pkrg0mx	187	10	in	in	IN
cord-321013-8pkrg0mx	187	11	RNA	RNA	NNP
cord-321013-8pkrg0mx	187	12	synthesis	synthesis	NN
cord-321013-8pkrg0mx	187	13	is	be	VBZ
cord-321013-8pkrg0mx	187	14	implied	imply	VBN
cord-321013-8pkrg0mx	187	15	by	by	IN
cord-321013-8pkrg0mx	187	16	at	at	RB
cord-321013-8pkrg0mx	187	17	least	least	RBS
cord-321013-8pkrg0mx	187	18	two	two	CD
cord-321013-8pkrg0mx	187	19	things	thing	NNS
cord-321013-8pkrg0mx	187	20	:	:	:
cord-321013-8pkrg0mx	187	21	firstly	firstly	RB
cord-321013-8pkrg0mx	187	22	MHV	MHV	NNP
cord-321013-8pkrg0mx	187	23	-	-	HYPH
cord-321013-8pkrg0mx	187	24	and	and	CC
cord-321013-8pkrg0mx	187	25	SARS	SARS	NNP
cord-321013-8pkrg0mx	187	26	-	-	HYPH
cord-321013-8pkrg0mx	187	27	CoV	CoV	NNP
cord-321013-8pkrg0mx	187	28	N	N	NNP
cord-321013-8pkrg0mx	187	29	protein	protein	NN
cord-321013-8pkrg0mx	187	30	colocalize	colocalize	NN
cord-321013-8pkrg0mx	187	31	intracellularly	intracellularly	RB
cord-321013-8pkrg0mx	187	32	with	with	IN
cord-321013-8pkrg0mx	187	33	replicase	replicase	NN
cord-321013-8pkrg0mx	187	34	components	component	NNS
cord-321013-8pkrg0mx	187	35	at	at	IN
cord-321013-8pkrg0mx	187	36	early	early	JJ
cord-321013-8pkrg0mx	187	37	stages	stage	NNS
cord-321013-8pkrg0mx	187	38	of	of	IN
cord-321013-8pkrg0mx	187	39	infection	infection	NN
cord-321013-8pkrg0mx	187	40	[	[	-LRB-
cord-321013-8pkrg0mx	187	41	122	122	CD
cord-321013-8pkrg0mx	187	42	]	]	-RRB-
cord-321013-8pkrg0mx	187	43	[	[	-LRB-
cord-321013-8pkrg0mx	187	44	123	123	CD
cord-321013-8pkrg0mx	187	45	]	]	-RRB-
cord-321013-8pkrg0mx	187	46	[	[	-LRB-
cord-321013-8pkrg0mx	187	47	124	124	CD
cord-321013-8pkrg0mx	187	48	]	]	-RRB-
cord-321013-8pkrg0mx	187	49	[	[	-LRB-
cord-321013-8pkrg0mx	187	50	125	125	CD
cord-321013-8pkrg0mx	187	51	]	]	-RRB-
cord-321013-8pkrg0mx	187	52	;	;	:
cord-321013-8pkrg0mx	187	53	and	and	CC
cord-321013-8pkrg0mx	187	54	secondly	secondly	RB
cord-321013-8pkrg0mx	187	55	,	,	,
cord-321013-8pkrg0mx	187	56	stimulation	stimulation	NN
cord-321013-8pkrg0mx	187	57	of	of	IN
cord-321013-8pkrg0mx	187	58	gRNA	gRNA	NNS
cord-321013-8pkrg0mx	187	59	infection	infection	NN
cord-321013-8pkrg0mx	187	60	is	be	VBZ
cord-321013-8pkrg0mx	187	61	dependent	dependent	JJ
cord-321013-8pkrg0mx	187	62	upon	upon	IN
cord-321013-8pkrg0mx	187	63	N	n	CD
cord-321013-8pkrg0mx	187	64	protein	protein	NN
cord-321013-8pkrg0mx	187	65	translation	translation	NN
cord-321013-8pkrg0mx	187	66	[	[	-LRB-
cord-321013-8pkrg0mx	187	67	52	52	CD
cord-321013-8pkrg0mx	187	68	,	,	,
cord-321013-8pkrg0mx	187	69	126	126	CD
cord-321013-8pkrg0mx	187	70	]	]	-RRB-
cord-321013-8pkrg0mx	187	71	.	.	.
cord-321013-8pkrg0mx	188	1	A	a	DT
cord-321013-8pkrg0mx	188	2	more	more	RBR
cord-321013-8pkrg0mx	188	3	clearly	clearly	RB
cord-321013-8pkrg0mx	188	4	defined	define	VBN
cord-321013-8pkrg0mx	188	5	role	role	NN
cord-321013-8pkrg0mx	188	6	for	for	IN
cord-321013-8pkrg0mx	188	7	N	n	CD
cord-321013-8pkrg0mx	188	8	protein	protein	NN
cord-321013-8pkrg0mx	188	9	in	in	IN
cord-321013-8pkrg0mx	188	10	gRNA	grna	NN
cord-321013-8pkrg0mx	188	11	synthesis	synthesis	NN
cord-321013-8pkrg0mx	188	12	was	be	VBD
cord-321013-8pkrg0mx	188	13	delineated	delineate	VBN
cord-321013-8pkrg0mx	188	14	when	when	WRB
cord-321013-8pkrg0mx	188	15	an	an	DT
cord-321013-8pkrg0mx	188	16	interaction	interaction	NN
cord-321013-8pkrg0mx	188	17	between	between	IN
cord-321013-8pkrg0mx	188	18	the	the	DT
cord-321013-8pkrg0mx	188	19	SR	SR	NNP
cord-321013-8pkrg0mx	188	20	region	region	NN
cord-321013-8pkrg0mx	188	21	of	of	IN
cord-321013-8pkrg0mx	188	22	the	the	DT
cord-321013-8pkrg0mx	188	23	MHV	MHV	NNP
cord-321013-8pkrg0mx	188	24	N	N	NNP
cord-321013-8pkrg0mx	188	25	protein	protein	NN
cord-321013-8pkrg0mx	188	26	and	and	CC
cord-321013-8pkrg0mx	188	27	a	a	DT
cord-321013-8pkrg0mx	188	28	region	region	NN
cord-321013-8pkrg0mx	188	29	in	in	IN
cord-321013-8pkrg0mx	188	30	the	the	DT
cord-321013-8pkrg0mx	188	31	amino	amino	NN
cord-321013-8pkrg0mx	188	32	terminal	terminal	NN
cord-321013-8pkrg0mx	188	33	segment	segment	NN
cord-321013-8pkrg0mx	188	34	of	of	IN
cord-321013-8pkrg0mx	188	35	the	the	DT
cord-321013-8pkrg0mx	188	36	nsp3	nsp3	NNS
cord-321013-8pkrg0mx	188	37	subunit	subunit	NN
cord-321013-8pkrg0mx	188	38	of	of	IN
cord-321013-8pkrg0mx	188	39	the	the	DT
cord-321013-8pkrg0mx	188	40	viral	viral	JJ
cord-321013-8pkrg0mx	188	41	replicase	replicase	NN
cord-321013-8pkrg0mx	188	42	was	be	VBD
cord-321013-8pkrg0mx	188	43	discovered	discover	VBN
cord-321013-8pkrg0mx	188	44	[	[	-LRB-
cord-321013-8pkrg0mx	188	45	51	51	CD
cord-321013-8pkrg0mx	188	46	,	,	,
cord-321013-8pkrg0mx	188	47	52	52	CD
cord-321013-8pkrg0mx	188	48	]	]	-RRB-
cord-321013-8pkrg0mx	188	49	.	.	.
cord-321013-8pkrg0mx	189	1	The	the	DT
cord-321013-8pkrg0mx	189	2	N	N	NNP
cord-321013-8pkrg0mx	189	3	-	-	HYPH
cord-321013-8pkrg0mx	189	4	nsp3	nsp3	NNS
cord-321013-8pkrg0mx	189	5	interaction	interaction	NN
cord-321013-8pkrg0mx	189	6	has	have	VBZ
cord-321013-8pkrg0mx	189	7	been	be	VBN
cord-321013-8pkrg0mx	189	8	specifically	specifically	RB
cord-321013-8pkrg0mx	189	9	mapped	map	VBN
cord-321013-8pkrg0mx	189	10	to	to	IN
cord-321013-8pkrg0mx	189	11	the	the	DT
cord-321013-8pkrg0mx	189	12	ubiquitin	ubiquitin	NN
cord-321013-8pkrg0mx	189	13	-	-	HYPH
cord-321013-8pkrg0mx	189	14	like	like	JJ
cord-321013-8pkrg0mx	189	15	domain	domain	NN
cord-321013-8pkrg0mx	189	16	(	(	-LRB-
cord-321013-8pkrg0mx	189	17	Ubl1	Ubl1	NNP
cord-321013-8pkrg0mx	189	18	)	)	-RRB-
cord-321013-8pkrg0mx	189	19	of	of	IN
cord-321013-8pkrg0mx	189	20	nsp3	nsp3	NNS
cord-321013-8pkrg0mx	189	21	,	,	,
cord-321013-8pkrg0mx	189	22	an	an	DT
cord-321013-8pkrg0mx	189	23	essential	essential	JJ
cord-321013-8pkrg0mx	189	24	domain	domain	NN
cord-321013-8pkrg0mx	189	25	to	to	IN
cord-321013-8pkrg0mx	189	26	the	the	DT
cord-321013-8pkrg0mx	189	27	virus	virus	NN
cord-321013-8pkrg0mx	189	28	[	[	-LRB-
cord-321013-8pkrg0mx	189	29	127	127	CD
cord-321013-8pkrg0mx	189	30	]	]	-RRB-
cord-321013-8pkrg0mx	189	31	.	.	.
cord-321013-8pkrg0mx	190	1	Moreover	moreover	RB
cord-321013-8pkrg0mx	190	2	,	,	,
cord-321013-8pkrg0mx	190	3	it	-PRON-	PRP
cord-321013-8pkrg0mx	190	4	was	be	VBD
cord-321013-8pkrg0mx	190	5	also	also	RB
cord-321013-8pkrg0mx	190	6	shown	show	VBN
cord-321013-8pkrg0mx	190	7	that	that	IN
cord-321013-8pkrg0mx	190	8	this	this	DT
cord-321013-8pkrg0mx	190	9	N	n	NN
cord-321013-8pkrg0mx	190	10	-	-	HYPH
cord-321013-8pkrg0mx	190	11	nsp3	nsp3	NNS
cord-321013-8pkrg0mx	190	12	interaction	interaction	NN
cord-321013-8pkrg0mx	190	13	is	be	VBZ
cord-321013-8pkrg0mx	190	14	required	require	VBN
cord-321013-8pkrg0mx	190	15	for	for	IN
cord-321013-8pkrg0mx	190	16	N	n	CD
cord-321013-8pkrg0mx	190	17	protein	protein	NN
cord-321013-8pkrg0mx	190	18	to	to	TO
cord-321013-8pkrg0mx	190	19	promote	promote	VB
cord-321013-8pkrg0mx	190	20	optimal	optimal	JJ
cord-321013-8pkrg0mx	190	21	infectivity	infectivity	NN
cord-321013-8pkrg0mx	190	22	of	of	IN
cord-321013-8pkrg0mx	190	23	gRNA	gRNA	NNS
cord-321013-8pkrg0mx	190	24	[	[	-LRB-
cord-321013-8pkrg0mx	190	25	52	52	CD
cord-321013-8pkrg0mx	190	26	]	]	-RRB-
cord-321013-8pkrg0mx	190	27	.	.	.
cord-321013-8pkrg0mx	191	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	191	2	was	be	VBD
cord-321013-8pkrg0mx	191	3	proposed	propose	VBN
cord-321013-8pkrg0mx	191	4	that	that	IN
cord-321013-8pkrg0mx	191	5	the	the	DT
cord-321013-8pkrg0mx	191	6	formation	formation	NN
cord-321013-8pkrg0mx	191	7	of	of	IN
cord-321013-8pkrg0mx	191	8	an	an	DT
cord-321013-8pkrg0mx	191	9	initiation	initiation	NN
cord-321013-8pkrg0mx	191	10	complex	complex	JJ
cord-321013-8pkrg0mx	191	11	at	at	IN
cord-321013-8pkrg0mx	191	12	the	the	DT
cord-321013-8pkrg0mx	191	13	3	3	CD
cord-321013-8pkrg0mx	191	14	'	'	NN
cord-321013-8pkrg0mx	191	15	end	end	NN
cord-321013-8pkrg0mx	191	16	of	of	IN
cord-321013-8pkrg0mx	191	17	the	the	DT
cord-321013-8pkrg0mx	191	18	genome	genome	NN
cord-321013-8pkrg0mx	191	19	requires	require	VBZ
cord-321013-8pkrg0mx	191	20	N	n	CD
cord-321013-8pkrg0mx	191	21	protein	protein	NN
cord-321013-8pkrg0mx	191	22	to	to	TO
cord-321013-8pkrg0mx	191	23	tether	tether	VB
cord-321013-8pkrg0mx	191	24	gRNA	gRNA	''
cord-321013-8pkrg0mx	191	25	to	to	IN
cord-321013-8pkrg0mx	191	26	the	the	DT
cord-321013-8pkrg0mx	191	27	newly	newly	RB
cord-321013-8pkrg0mx	191	28	translated	translate	VBN
cord-321013-8pkrg0mx	191	29	replicase	replicase	NN
cord-321013-8pkrg0mx	191	30	via	via	IN
cord-321013-8pkrg0mx	191	31	its	-PRON-	PRP$
cord-321013-8pkrg0mx	191	32	interaction	interaction	NN
cord-321013-8pkrg0mx	191	33	with	with	IN
cord-321013-8pkrg0mx	191	34	nsp3	nsp3	NNS
cord-321013-8pkrg0mx	191	35	[	[	-LRB-
cord-321013-8pkrg0mx	191	36	52	52	CD
cord-321013-8pkrg0mx	191	37	,	,	,
cord-321013-8pkrg0mx	191	38	127	127	CD
cord-321013-8pkrg0mx	191	39	]	]	-RRB-
cord-321013-8pkrg0mx	191	40	.	.	.
cord-321013-8pkrg0mx	192	1	Considering	consider	VBG
cord-321013-8pkrg0mx	192	2	that	that	IN
cord-321013-8pkrg0mx	192	3	the	the	DT
cord-321013-8pkrg0mx	192	4	start	start	NN
cord-321013-8pkrg0mx	192	5	of	of	IN
cord-321013-8pkrg0mx	192	6	negative	negative	JJ
cord-321013-8pkrg0mx	192	7	-	-	HYPH
cord-321013-8pkrg0mx	192	8	strand	strand	NN
cord-321013-8pkrg0mx	192	9	synthesis	synthesis	NN
cord-321013-8pkrg0mx	192	10	is	be	VBZ
cord-321013-8pkrg0mx	192	11	the	the	DT
cord-321013-8pkrg0mx	192	12	first	first	JJ
cord-321013-8pkrg0mx	192	13	step	step	NN
cord-321013-8pkrg0mx	192	14	in	in	IN
cord-321013-8pkrg0mx	192	15	both	both	DT
cord-321013-8pkrg0mx	192	16	genomic	genomic	JJ
cord-321013-8pkrg0mx	192	17	replication	replication	NN
cord-321013-8pkrg0mx	192	18	and	and	CC
cord-321013-8pkrg0mx	192	19	transcription	transcription	NN
cord-321013-8pkrg0mx	192	20	[	[	-LRB-
cord-321013-8pkrg0mx	192	21	128	128	CD
cord-321013-8pkrg0mx	192	22	,	,	,
cord-321013-8pkrg0mx	192	23	129	129	CD
cord-321013-8pkrg0mx	192	24	]	]	-RRB-
cord-321013-8pkrg0mx	192	25	,	,	,
cord-321013-8pkrg0mx	192	26	it	-PRON-	PRP
cord-321013-8pkrg0mx	192	27	is	be	VBZ
cord-321013-8pkrg0mx	192	28	likely	likely	JJ
cord-321013-8pkrg0mx	192	29	that	that	IN
cord-321013-8pkrg0mx	192	30	this	this	DT
cord-321013-8pkrg0mx	192	31	N	n	NN
cord-321013-8pkrg0mx	192	32	-	-	HYPH
cord-321013-8pkrg0mx	192	33	nsp3	nsp3	NNS
cord-321013-8pkrg0mx	192	34	interaction	interaction	NN
cord-321013-8pkrg0mx	192	35	is	be	VBZ
cord-321013-8pkrg0mx	192	36	important	important	JJ
cord-321013-8pkrg0mx	192	37	in	in	IN
cord-321013-8pkrg0mx	192	38	both	both	DT
cord-321013-8pkrg0mx	192	39	of	of	IN
cord-321013-8pkrg0mx	192	40	these	these	DT
cord-321013-8pkrg0mx	192	41	RNA	RNA	NNP
cord-321013-8pkrg0mx	192	42	-	-	HYPH
cord-321013-8pkrg0mx	192	43	synthetic	synthetic	JJ
cord-321013-8pkrg0mx	192	44	processes	process	NNS
cord-321013-8pkrg0mx	192	45	[	[	-LRB-
cord-321013-8pkrg0mx	192	46	52	52	CD
cord-321013-8pkrg0mx	192	47	]	]	-RRB-
cord-321013-8pkrg0mx	192	48	.	.	.
cord-321013-8pkrg0mx	193	1	The	the	DT
cord-321013-8pkrg0mx	193	2	role	role	NN
cord-321013-8pkrg0mx	193	3	of	of	IN
cord-321013-8pkrg0mx	193	4	N	n	CD
cord-321013-8pkrg0mx	193	5	protein	protein	NN
cord-321013-8pkrg0mx	193	6	in	in	IN
cord-321013-8pkrg0mx	193	7	MHV	MHV	NNP
cord-321013-8pkrg0mx	193	8	gRNA	grna	NN
cord-321013-8pkrg0mx	193	9	synthesis	synthesis	NN
cord-321013-8pkrg0mx	193	10	may	may	MD
cord-321013-8pkrg0mx	193	11	not	not	RB
cord-321013-8pkrg0mx	193	12	necessarily	necessarily	RB
cord-321013-8pkrg0mx	193	13	be	be	VB
cord-321013-8pkrg0mx	193	14	limited	limit	VBN
cord-321013-8pkrg0mx	193	15	to	to	IN
cord-321013-8pkrg0mx	193	16	early	early	JJ
cord-321013-8pkrg0mx	193	17	time	time	NN
cord-321013-8pkrg0mx	193	18	points	point	NNS
cord-321013-8pkrg0mx	193	19	of	of	IN
cord-321013-8pkrg0mx	193	20	infection	infection	NN
cord-321013-8pkrg0mx	193	21	as	as	IN
cord-321013-8pkrg0mx	193	22	it	-PRON-	PRP
cord-321013-8pkrg0mx	193	23	has	have	VBZ
cord-321013-8pkrg0mx	193	24	also	also	RB
cord-321013-8pkrg0mx	193	25	been	be	VBN
cord-321013-8pkrg0mx	193	26	proposed	propose	VBN
cord-321013-8pkrg0mx	193	27	that	that	IN
cord-321013-8pkrg0mx	193	28	N	n	CD
cord-321013-8pkrg0mx	193	29	protein	protein	NN
cord-321013-8pkrg0mx	193	30	sustains	sustain	VBZ
cord-321013-8pkrg0mx	193	31	ongoing	ongoing	JJ
cord-321013-8pkrg0mx	193	32	transcription	transcription	NN
cord-321013-8pkrg0mx	193	33	throughout	throughout	IN
cord-321013-8pkrg0mx	193	34	the	the	DT
cord-321013-8pkrg0mx	193	35	course	course	NN
cord-321013-8pkrg0mx	193	36	of	of	IN
cord-321013-8pkrg0mx	193	37	infection	infection	NN
cord-321013-8pkrg0mx	193	38	[	[	-LRB-
cord-321013-8pkrg0mx	193	39	31	31	CD
cord-321013-8pkrg0mx	193	40	,	,	,
cord-321013-8pkrg0mx	193	41	130	130	CD
cord-321013-8pkrg0mx	193	42	]	]	-RRB-
cord-321013-8pkrg0mx	193	43	.	.	.
cord-321013-8pkrg0mx	194	1	The	the	DT
cord-321013-8pkrg0mx	194	2	role	role	NN
cord-321013-8pkrg0mx	194	3	of	of	IN
cord-321013-8pkrg0mx	194	4	CoV	CoV	NNP
cord-321013-8pkrg0mx	194	5	N	n	CD
cord-321013-8pkrg0mx	194	6	protein	protein	NN
cord-321013-8pkrg0mx	194	7	in	in	IN
cord-321013-8pkrg0mx	194	8	RNA	RNA	NNP
cord-321013-8pkrg0mx	194	9	synthesis	synthesis	NN
cord-321013-8pkrg0mx	194	10	remains	remain	VBZ
cord-321013-8pkrg0mx	194	11	controversial	controversial	JJ
cord-321013-8pkrg0mx	194	12	as	as	IN
cord-321013-8pkrg0mx	194	13	N	n	CD
cord-321013-8pkrg0mx	194	14	protein	protein	NN
cord-321013-8pkrg0mx	194	15	is	be	VBZ
cord-321013-8pkrg0mx	194	16	not	not	RB
cord-321013-8pkrg0mx	194	17	essential	essential	JJ
cord-321013-8pkrg0mx	194	18	for	for	IN
cord-321013-8pkrg0mx	194	19	TGEV	TGEV	NNP
cord-321013-8pkrg0mx	194	20	RNA	RNA	NNP
cord-321013-8pkrg0mx	194	21	replication	replication	NN
cord-321013-8pkrg0mx	194	22	but	but	CC
cord-321013-8pkrg0mx	194	23	rather	rather	RB
cord-321013-8pkrg0mx	194	24	for	for	IN
cord-321013-8pkrg0mx	194	25	efficient	efficient	JJ
cord-321013-8pkrg0mx	194	26	transcription	transcription	NN
cord-321013-8pkrg0mx	194	27	[	[	-LRB-
cord-321013-8pkrg0mx	194	28	31	31	CD
cord-321013-8pkrg0mx	194	29	]	]	-RRB-
cord-321013-8pkrg0mx	194	30	.	.	.
cord-321013-8pkrg0mx	195	1	RNA	RNA	NNP
cord-321013-8pkrg0mx	195	2	chaperone	chaperone	NN
cord-321013-8pkrg0mx	195	3	proteins	protein	NNS
cord-321013-8pkrg0mx	195	4	assist	assist	VBP
cord-321013-8pkrg0mx	195	5	the	the	DT
cord-321013-8pkrg0mx	195	6	proper	proper	JJ
cord-321013-8pkrg0mx	195	7	folding	folding	NN
cord-321013-8pkrg0mx	195	8	of	of	IN
cord-321013-8pkrg0mx	195	9	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	195	10	acids	acid	NNS
cord-321013-8pkrg0mx	195	11	[	[	-LRB-
cord-321013-8pkrg0mx	195	12	131	131	CD
cord-321013-8pkrg0mx	195	13	,	,	,
cord-321013-8pkrg0mx	195	14	132	132	CD
cord-321013-8pkrg0mx	195	15	]	]	-RRB-
cord-321013-8pkrg0mx	195	16	.	.	.
cord-321013-8pkrg0mx	196	1	Chaperone	chaperone	NN
cord-321013-8pkrg0mx	196	2	activity	activity	NN
cord-321013-8pkrg0mx	196	3	has	have	VBZ
cord-321013-8pkrg0mx	196	4	been	be	VBN
cord-321013-8pkrg0mx	196	5	postulated	postulate	VBN
cord-321013-8pkrg0mx	196	6	as	as	IN
cord-321013-8pkrg0mx	196	7	a	a	DT
cord-321013-8pkrg0mx	196	8	general	general	JJ
cord-321013-8pkrg0mx	196	9	activity	activity	NN
cord-321013-8pkrg0mx	196	10	of	of	IN
cord-321013-8pkrg0mx	196	11	all	all	DT
cord-321013-8pkrg0mx	196	12	CoV	cov	NN
cord-321013-8pkrg0mx	196	13	N	n	CD
cord-321013-8pkrg0mx	196	14	proteins	protein	NNS
cord-321013-8pkrg0mx	196	15	,	,	,
cord-321013-8pkrg0mx	196	16	and	and	CC
cord-321013-8pkrg0mx	196	17	has	have	VBZ
cord-321013-8pkrg0mx	196	18	been	be	VBN
cord-321013-8pkrg0mx	196	19	demonstrated	demonstrate	VBN
cord-321013-8pkrg0mx	196	20	for	for	IN
cord-321013-8pkrg0mx	196	21	TGEVand	tgevand	JJ
cord-321013-8pkrg0mx	196	22	SARS	SARS	NNP
cord-321013-8pkrg0mx	196	23	-	-	HYPH
cord-321013-8pkrg0mx	196	24	CoV	CoV	NNP
cord-321013-8pkrg0mx	196	25	N	n	CD
cord-321013-8pkrg0mx	196	26	proteins	protein	NNS
cord-321013-8pkrg0mx	196	27	[	[	-LRB-
cord-321013-8pkrg0mx	196	28	30	30	CD
cord-321013-8pkrg0mx	196	29	]	]	-RRB-
cord-321013-8pkrg0mx	196	30	.	.	.
cord-321013-8pkrg0mx	197	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	197	2	has	have	VBZ
cord-321013-8pkrg0mx	197	3	been	be	VBN
cord-321013-8pkrg0mx	197	4	proposed	propose	VBN
cord-321013-8pkrg0mx	197	5	that	that	IN
cord-321013-8pkrg0mx	197	6	amino	amino	JJ
cord-321013-8pkrg0mx	197	7	acids	acid	NNS
cord-321013-8pkrg0mx	197	8	117	117	CD
cord-321013-8pkrg0mx	197	9	-	-	SYM
cord-321013-8pkrg0mx	197	10	268	268	CD
cord-321013-8pkrg0mx	197	11	in	in	IN
cord-321013-8pkrg0mx	197	12	the	the	DT
cord-321013-8pkrg0mx	197	13	central	central	JJ
cord-321013-8pkrg0mx	197	14	disordered	disordered	JJ
cord-321013-8pkrg0mx	197	15	domain	domain	NN
cord-321013-8pkrg0mx	197	16	(	(	-LRB-
cord-321013-8pkrg0mx	197	17	the	the	DT
cord-321013-8pkrg0mx	197	18	LKR	LKR	NNP
cord-321013-8pkrg0mx	197	19	domain	domain	NN
cord-321013-8pkrg0mx	197	20	)	)	-RRB-
cord-321013-8pkrg0mx	197	21	of	of	IN
cord-321013-8pkrg0mx	197	22	the	the	DT
cord-321013-8pkrg0mx	197	23	TGEV	TGEV	NNP
cord-321013-8pkrg0mx	197	24	N	N	NNP
cord-321013-8pkrg0mx	197	25	protein	protein	NN
cord-321013-8pkrg0mx	197	26	has	have	VBZ
cord-321013-8pkrg0mx	197	27	chaperone	chaperone	NN
cord-321013-8pkrg0mx	197	28	activity	activity	NN
cord-321013-8pkrg0mx	197	29	[	[	-LRB-
cord-321013-8pkrg0mx	197	30	31	31	CD
cord-321013-8pkrg0mx	197	31	]	]	-RRB-
cord-321013-8pkrg0mx	197	32	,	,	,
cord-321013-8pkrg0mx	197	33	and	and	CC
cord-321013-8pkrg0mx	197	34	that	that	IN
cord-321013-8pkrg0mx	197	35	this	this	DT
cord-321013-8pkrg0mx	197	36	region	region	NN
cord-321013-8pkrg0mx	197	37	facilitates	facilitate	VBZ
cord-321013-8pkrg0mx	197	38	template	template	NN
cord-321013-8pkrg0mx	197	39	switching	switch	VBG
cord-321013-8pkrg0mx	197	40	in	in	IN
cord-321013-8pkrg0mx	197	41	vitro	vitro	FW
cord-321013-8pkrg0mx	197	42	by	by	IN
cord-321013-8pkrg0mx	197	43	decreasing	decrease	VBG
cord-321013-8pkrg0mx	197	44	the	the	DT
cord-321013-8pkrg0mx	197	45	energy	energy	NN
cord-321013-8pkrg0mx	197	46	barrier	barrier	NN
cord-321013-8pkrg0mx	197	47	needed	need	VBN
cord-321013-8pkrg0mx	197	48	to	to	TO
cord-321013-8pkrg0mx	197	49	dissociate	dissociate	VB
cord-321013-8pkrg0mx	197	50	the	the	DT
cord-321013-8pkrg0mx	197	51	nascent	nascent	JJ
cord-321013-8pkrg0mx	197	52	minus	minus	CC
cord-321013-8pkrg0mx	197	53	RNA	RNA	NNP
cord-321013-8pkrg0mx	197	54	chain	chain	NN
cord-321013-8pkrg0mx	197	55	from	from	IN
cord-321013-8pkrg0mx	197	56	the	the	DT
cord-321013-8pkrg0mx	197	57	gRNA	grna	NN
cord-321013-8pkrg0mx	197	58	template	template	NN
cord-321013-8pkrg0mx	197	59	during	during	IN
cord-321013-8pkrg0mx	197	60	discontinuous	discontinuous	JJ
cord-321013-8pkrg0mx	197	61	RNA	RNA	NNP
cord-321013-8pkrg0mx	197	62	transcription	transcription	NN
cord-321013-8pkrg0mx	197	63	[	[	-LRB-
cord-321013-8pkrg0mx	197	64	30	30	CD
cord-321013-8pkrg0mx	197	65	,	,	,
cord-321013-8pkrg0mx	197	66	31	31	CD
cord-321013-8pkrg0mx	197	67	]	]	-RRB-
cord-321013-8pkrg0mx	197	68	.	.	.
cord-321013-8pkrg0mx	198	1	This	this	DT
cord-321013-8pkrg0mx	198	2	facilitation	facilitation	NN
cord-321013-8pkrg0mx	198	3	of	of	IN
cord-321013-8pkrg0mx	198	4	template	template	NN
cord-321013-8pkrg0mx	198	5	switching	switching	NN
cord-321013-8pkrg0mx	198	6	is	be	VBZ
cord-321013-8pkrg0mx	198	7	required	require	VBN
cord-321013-8pkrg0mx	198	8	for	for	IN
cord-321013-8pkrg0mx	198	9	efficient	efficient	JJ
cord-321013-8pkrg0mx	198	10	transcription	transcription	NN
cord-321013-8pkrg0mx	198	11	and	and	CC
cord-321013-8pkrg0mx	198	12	may	may	MD
cord-321013-8pkrg0mx	198	13	explain	explain	VB
cord-321013-8pkrg0mx	198	14	how	how	WRB
cord-321013-8pkrg0mx	198	15	the	the	DT
cord-321013-8pkrg0mx	198	16	presence	presence	NN
cord-321013-8pkrg0mx	198	17	of	of	IN
cord-321013-8pkrg0mx	198	18	N	n	CD
cord-321013-8pkrg0mx	198	19	protein	protein	NN
cord-321013-8pkrg0mx	198	20	therefore	therefore	RB
cord-321013-8pkrg0mx	198	21	increases	increase	VBZ
cord-321013-8pkrg0mx	198	22	RNA	RNA	NNP
cord-321013-8pkrg0mx	198	23	synthesis	synthesis	NN
cord-321013-8pkrg0mx	198	24	.	.	.
cord-321013-8pkrg0mx	199	1	Deregulation	deregulation	NN
cord-321013-8pkrg0mx	199	2	of	of	IN
cord-321013-8pkrg0mx	199	3	the	the	DT
cord-321013-8pkrg0mx	199	4	cell	cell	NN
cord-321013-8pkrg0mx	199	5	cycle	cycle	NN
cord-321013-8pkrg0mx	199	6	is	be	VBZ
cord-321013-8pkrg0mx	199	7	a	a	DT
cord-321013-8pkrg0mx	199	8	common	common	JJ
cord-321013-8pkrg0mx	199	9	strategy	strategy	NN
cord-321013-8pkrg0mx	199	10	adopted	adopt	VBN
cord-321013-8pkrg0mx	199	11	by	by	IN
cord-321013-8pkrg0mx	199	12	many	many	JJ
cord-321013-8pkrg0mx	199	13	RNA	RNA	NNP
cord-321013-8pkrg0mx	199	14	(	(	-LRB-
cord-321013-8pkrg0mx	199	15	and	and	CC
cord-321013-8pkrg0mx	199	16	DNA	DNA	NNP
cord-321013-8pkrg0mx	199	17	)	)	-RRB-
cord-321013-8pkrg0mx	199	18	viruses	virus	NNS
cord-321013-8pkrg0mx	199	19	aimed	aim	VBN
cord-321013-8pkrg0mx	199	20	at	at	IN
cord-321013-8pkrg0mx	199	21	exploiting	exploit	VBG
cord-321013-8pkrg0mx	199	22	host	host	NN
cord-321013-8pkrg0mx	199	23	cell	cell	NN
cord-321013-8pkrg0mx	199	24	machinery	machinery	NN
cord-321013-8pkrg0mx	199	25	in	in	IN
cord-321013-8pkrg0mx	199	26	order	order	NN
cord-321013-8pkrg0mx	199	27	to	to	TO
cord-321013-8pkrg0mx	199	28	create	create	VB
cord-321013-8pkrg0mx	199	29	a	a	DT
cord-321013-8pkrg0mx	199	30	more	more	RBR
cord-321013-8pkrg0mx	199	31	favorable	favorable	JJ
cord-321013-8pkrg0mx	199	32	environment	environment	NN
cord-321013-8pkrg0mx	199	33	for	for	IN
cord-321013-8pkrg0mx	199	34	their	-PRON-	PRP$
cord-321013-8pkrg0mx	199	35	survival	survival	NN
cord-321013-8pkrg0mx	199	36	.	.	.
cord-321013-8pkrg0mx	200	1	One	one	CD
cord-321013-8pkrg0mx	200	2	of	of	IN
cord-321013-8pkrg0mx	200	3	the	the	DT
cord-321013-8pkrg0mx	200	4	MHV	MHV	NNP
cord-321013-8pkrg0mx	200	5	nonstructural	nonstructural	JJ
cord-321013-8pkrg0mx	200	6	proteins	protein	NNS
cord-321013-8pkrg0mx	200	7	,	,	,
cord-321013-8pkrg0mx	200	8	p28	p28	CD
cord-321013-8pkrg0mx	200	9	,	,	,
cord-321013-8pkrg0mx	200	10	induces	induce	VBZ
cord-321013-8pkrg0mx	200	11	G	g	NN
cord-321013-8pkrg0mx	200	12	0	0	CD
cord-321013-8pkrg0mx	200	13	/G	/g	SYM
cord-321013-8pkrg0mx	200	14	1	1	CD
cord-321013-8pkrg0mx	200	15	cell	cell	NN
cord-321013-8pkrg0mx	200	16	cycle	cycle	NN
cord-321013-8pkrg0mx	200	17	arrest	arrest	NN
cord-321013-8pkrg0mx	200	18	by	by	IN
cord-321013-8pkrg0mx	200	19	inhibiting	inhibit	VBG
cord-321013-8pkrg0mx	200	20	hyperphosphorylation	hyperphosphorylation	NN
cord-321013-8pkrg0mx	200	21	of	of	IN
cord-321013-8pkrg0mx	200	22	retinoblastoma	retinoblastoma	NN
cord-321013-8pkrg0mx	200	23	protein	protein	NN
cord-321013-8pkrg0mx	200	24	(	(	-LRB-
cord-321013-8pkrg0mx	200	25	Rb	Rb	NNP
cord-321013-8pkrg0mx	200	26	)	)	-RRB-
cord-321013-8pkrg0mx	200	27	,	,	,
cord-321013-8pkrg0mx	200	28	a	a	DT
cord-321013-8pkrg0mx	200	29	step	step	NN
cord-321013-8pkrg0mx	200	30	which	which	WDT
cord-321013-8pkrg0mx	200	31	is	be	VBZ
cord-321013-8pkrg0mx	200	32	necessary	necessary	JJ
cord-321013-8pkrg0mx	200	33	for	for	IN
cord-321013-8pkrg0mx	200	34	cell	cell	NN
cord-321013-8pkrg0mx	200	35	cycle	cycle	NN
cord-321013-8pkrg0mx	200	36	progression	progression	NN
cord-321013-8pkrg0mx	200	37	through	through	IN
cord-321013-8pkrg0mx	200	38	late	late	JJ
cord-321013-8pkrg0mx	200	39	G	g	NN
cord-321013-8pkrg0mx	200	40	1	1	CD
cord-321013-8pkrg0mx	200	41	into	into	IN
cord-321013-8pkrg0mx	200	42	the	the	DT
cord-321013-8pkrg0mx	200	43	S	S	NNP
cord-321013-8pkrg0mx	200	44	phase	phase	NN
cord-321013-8pkrg0mx	200	45	[	[	-LRB-
cord-321013-8pkrg0mx	200	46	133	133	CD
cord-321013-8pkrg0mx	200	47	]	]	-RRB-
cord-321013-8pkrg0mx	200	48	[	[	-LRB-
cord-321013-8pkrg0mx	200	49	134	134	CD
cord-321013-8pkrg0mx	200	50	]	]	-RRB-
cord-321013-8pkrg0mx	200	51	[	[	-LRB-
cord-321013-8pkrg0mx	200	52	135	135	CD
cord-321013-8pkrg0mx	200	53	]	]	-RRB-
cord-321013-8pkrg0mx	200	54	.	.	.
cord-321013-8pkrg0mx	201	1	A	a	DT
cord-321013-8pkrg0mx	201	2	model	model	NN
cord-321013-8pkrg0mx	201	3	was	be	VBD
cord-321013-8pkrg0mx	201	4	proposed	propose	VBN
cord-321013-8pkrg0mx	201	5	whereby	whereby	NN
cord-321013-8pkrg0mx	201	6	expressed	express	VBD
cord-321013-8pkrg0mx	201	7	cytoplasmic	cytoplasmic	JJ
cord-321013-8pkrg0mx	201	8	p28	p28	NNP
cord-321013-8pkrg0mx	201	9	induces	induce	VBZ
cord-321013-8pkrg0mx	201	10	stabilization	stabilization	NN
cord-321013-8pkrg0mx	201	11	of	of	IN
cord-321013-8pkrg0mx	201	12	p53	p53	NN
cord-321013-8pkrg0mx	201	13	,	,	,
cord-321013-8pkrg0mx	201	14	and	and	CC
cord-321013-8pkrg0mx	201	15	accumulation	accumulation	NN
cord-321013-8pkrg0mx	201	16	of	of	IN
cord-321013-8pkrg0mx	201	17	p53	p53	NN
cord-321013-8pkrg0mx	201	18	causes	cause	NNS
cord-321013-8pkrg0mx	201	19	transcriptional	transcriptional	JJ
cord-321013-8pkrg0mx	201	20	upregulation	upregulation	NN
cord-321013-8pkrg0mx	201	21	of	of	IN
cord-321013-8pkrg0mx	201	22	p21	p21	NN
cord-321013-8pkrg0mx	201	23	,	,	,
cord-321013-8pkrg0mx	201	24	a	a	DT
cord-321013-8pkrg0mx	201	25	cyclin	cyclin	NN
cord-321013-8pkrg0mx	201	26	-	-	HYPH
cord-321013-8pkrg0mx	201	27	dependent	dependent	JJ
cord-321013-8pkrg0mx	201	28	kinase	kinase	NN
cord-321013-8pkrg0mx	201	29	(	(	-LRB-
cord-321013-8pkrg0mx	201	30	CDK	CDK	NNP
cord-321013-8pkrg0mx	201	31	)	)	-RRB-
cord-321013-8pkrg0mx	201	32	inhibitor	inhibitor	NN
cord-321013-8pkrg0mx	201	33	,	,	,
cord-321013-8pkrg0mx	201	34	leading	lead	VBG
cord-321013-8pkrg0mx	201	35	to	to	IN
cord-321013-8pkrg0mx	201	36	suppression	suppression	NN
cord-321013-8pkrg0mx	201	37	of	of	IN
cord-321013-8pkrg0mx	201	38	cyclin	cyclin	NN
cord-321013-8pkrg0mx	201	39	E	E	NNP
cord-321013-8pkrg0mx	201	40	/	/	SYM
cord-321013-8pkrg0mx	201	41	CDK	CDK	NNP
cord-321013-8pkrg0mx	201	42	2	2	CD
cord-321013-8pkrg0mx	201	43	activities	activity	NNS
cord-321013-8pkrg0mx	201	44	,	,	,
cord-321013-8pkrg0mx	201	45	and	and	CC
cord-321013-8pkrg0mx	201	46	the	the	DT
cord-321013-8pkrg0mx	201	47	resulting	result	VBG
cord-321013-8pkrg0mx	201	48	reduction	reduction	NN
cord-321013-8pkrg0mx	201	49	in	in	IN
cord-321013-8pkrg0mx	201	50	G	g	NN
cord-321013-8pkrg0mx	201	51	1	1	CD
cord-321013-8pkrg0mx	201	52	cyclin	cyclin	NN
cord-321013-8pkrg0mx	201	53	-	-	HYPH
cord-321013-8pkrg0mx	201	54	CDK	CDK	NNP
cord-321013-8pkrg0mx	201	55	complexes	complex	NNS
cord-321013-8pkrg0mx	201	56	and	and	CC
cord-321013-8pkrg0mx	201	57	CDK	CDK	NNP
cord-321013-8pkrg0mx	201	58	activities	activity	NNS
cord-321013-8pkrg0mx	201	59	ultimately	ultimately	RB
cord-321013-8pkrg0mx	201	60	inhibits	inhibit	VBZ
cord-321013-8pkrg0mx	201	61	Rb	Rb	NNP
cord-321013-8pkrg0mx	201	62	hyperphosphorylation	hyperphosphorylation	NN
cord-321013-8pkrg0mx	201	63	[	[	-LRB-
cord-321013-8pkrg0mx	201	64	133	133	CD
cord-321013-8pkrg0mx	201	65	]	]	-RRB-
cord-321013-8pkrg0mx	201	66	.	.	.
cord-321013-8pkrg0mx	202	1	Certain	certain	JJ
cord-321013-8pkrg0mx	202	2	herpes	herpes	NN
cord-321013-8pkrg0mx	202	3	simplex	simplex	NN
cord-321013-8pkrg0mx	202	4	virus	virus	NN
cord-321013-8pkrg0mx	202	5	gene	gene	NN
cord-321013-8pkrg0mx	202	6	products	product	NNS
cord-321013-8pkrg0mx	202	7	[	[	-LRB-
cord-321013-8pkrg0mx	202	8	136	136	CD
cord-321013-8pkrg0mx	202	9	,	,	,
cord-321013-8pkrg0mx	202	10	137	137	CD
cord-321013-8pkrg0mx	202	11	]	]	-RRB-
cord-321013-8pkrg0mx	202	12	,	,	,
cord-321013-8pkrg0mx	202	13	cytomegalovirus	cytomegalovirus	JJ
cord-321013-8pkrg0mx	202	14	gene	gene	NN
cord-321013-8pkrg0mx	202	15	products	product	NNS
cord-321013-8pkrg0mx	202	16	[	[	-LRB-
cord-321013-8pkrg0mx	202	17	138	138	CD
cord-321013-8pkrg0mx	202	18	,	,	,
cord-321013-8pkrg0mx	202	19	139	139	CD
cord-321013-8pkrg0mx	202	20	]	]	-RRB-
cord-321013-8pkrg0mx	202	21	,	,	,
cord-321013-8pkrg0mx	202	22	and	and	CC
cord-321013-8pkrg0mx	202	23	Zta	Zta	NNP
cord-321013-8pkrg0mx	202	24	of	of	IN
cord-321013-8pkrg0mx	202	25	Epstein	Epstein	NNP
cord-321013-8pkrg0mx	202	26	-	-	HYPH
cord-321013-8pkrg0mx	202	27	Barr	Barr	NNP
cord-321013-8pkrg0mx	202	28	virus	virus	NN
cord-321013-8pkrg0mx	202	29	[	[	-LRB-
cord-321013-8pkrg0mx	202	30	140	140	CD
cord-321013-8pkrg0mx	202	31	]	]	-RRB-
cord-321013-8pkrg0mx	202	32	have	have	VBP
cord-321013-8pkrg0mx	202	33	similarly	similarly	RB
cord-321013-8pkrg0mx	202	34	also	also	RB
cord-321013-8pkrg0mx	202	35	been	be	VBN
cord-321013-8pkrg0mx	202	36	shown	show	VBN
cord-321013-8pkrg0mx	202	37	to	to	TO
cord-321013-8pkrg0mx	202	38	arrest	arrest	VB
cord-321013-8pkrg0mx	202	39	cell	cell	NN
cord-321013-8pkrg0mx	202	40	cycle	cycle	NN
cord-321013-8pkrg0mx	202	41	progression	progression	NN
cord-321013-8pkrg0mx	202	42	at	at	IN
cord-321013-8pkrg0mx	202	43	the	the	DT
cord-321013-8pkrg0mx	202	44	G	g	NN
cord-321013-8pkrg0mx	202	45	1	1	CD
cord-321013-8pkrg0mx	202	46	phase	phase	NN
cord-321013-8pkrg0mx	202	47	.	.	.
cord-321013-8pkrg0mx	203	1	IBV	IBV	NNP
cord-321013-8pkrg0mx	203	2	infection	infection	NN
cord-321013-8pkrg0mx	203	3	also	also	RB
cord-321013-8pkrg0mx	203	4	perturbs	perturb	VBZ
cord-321013-8pkrg0mx	203	5	cell	cell	NN
cord-321013-8pkrg0mx	203	6	cycle	cycle	NN
cord-321013-8pkrg0mx	203	7	progression	progression	NN
cord-321013-8pkrg0mx	203	8	and	and	CC
cord-321013-8pkrg0mx	203	9	arrests	arrest	NNS
cord-321013-8pkrg0mx	203	10	cells	cell	NNS
cord-321013-8pkrg0mx	203	11	in	in	IN
cord-321013-8pkrg0mx	203	12	the	the	DT
cord-321013-8pkrg0mx	203	13	S	S	NNP
cord-321013-8pkrg0mx	203	14	and	and	CC
cord-321013-8pkrg0mx	203	15	G	G	NNP
cord-321013-8pkrg0mx	203	16	2	2	CD
cord-321013-8pkrg0mx	203	17	/M	/M	.
cord-321013-8pkrg0mx	203	18	phases	phase	NNS
cord-321013-8pkrg0mx	203	19	,	,	,
cord-321013-8pkrg0mx	203	20	and	and	CC
cord-321013-8pkrg0mx	203	21	this	this	DT
cord-321013-8pkrg0mx	203	22	occurs	occur	VBZ
cord-321013-8pkrg0mx	203	23	partly	partly	RB
cord-321013-8pkrg0mx	203	24	through	through	IN
cord-321013-8pkrg0mx	203	25	the	the	DT
cord-321013-8pkrg0mx	203	26	interaction	interaction	NN
cord-321013-8pkrg0mx	203	27	of	of	IN
cord-321013-8pkrg0mx	203	28	IBV	IBV	NNP
cord-321013-8pkrg0mx	203	29	nsp3	nsp3	NNS
cord-321013-8pkrg0mx	203	30	and	and	CC
cord-321013-8pkrg0mx	203	31	DNA	dna	NN
cord-321013-8pkrg0mx	203	32	polymerase	polymerase	NN
cord-321013-8pkrg0mx	203	33	delta	delta	NN
cord-321013-8pkrg0mx	203	34	[	[	-LRB-
cord-321013-8pkrg0mx	203	35	141	141	CD
cord-321013-8pkrg0mx	203	36	]	]	-RRB-
cord-321013-8pkrg0mx	203	37	.	.	.
cord-321013-8pkrg0mx	204	1	The	the	DT
cord-321013-8pkrg0mx	204	2	N	N	NNP
cord-321013-8pkrg0mx	204	3	protein	protein	NN
cord-321013-8pkrg0mx	204	4	of	of	IN
cord-321013-8pkrg0mx	204	5	SARS	SARS	NNP
cord-321013-8pkrg0mx	204	6	-	-	HYPH
cord-321013-8pkrg0mx	204	7	CoV	CoV	NNP
cord-321013-8pkrg0mx	204	8	also	also	RB
cord-321013-8pkrg0mx	204	9	modulates	modulate	VBZ
cord-321013-8pkrg0mx	204	10	the	the	DT
cord-321013-8pkrg0mx	204	11	host	host	NN
cord-321013-8pkrg0mx	204	12	cell	cell	NN
cord-321013-8pkrg0mx	204	13	cycle	cycle	NN
cord-321013-8pkrg0mx	204	14	by	by	IN
cord-321013-8pkrg0mx	204	15	regulating	regulate	VBG
cord-321013-8pkrg0mx	204	16	cyclin	cyclin	NN
cord-321013-8pkrg0mx	204	17	-	-	HYPH
cord-321013-8pkrg0mx	204	18	CDK	CDK	NNP
cord-321013-8pkrg0mx	204	19	activity	activity	NN
cord-321013-8pkrg0mx	204	20	such	such	JJ
cord-321013-8pkrg0mx	204	21	that	that	IN
cord-321013-8pkrg0mx	204	22	S	s	NN
cord-321013-8pkrg0mx	204	23	phase	phase	NN
cord-321013-8pkrg0mx	204	24	progression	progression	NN
cord-321013-8pkrg0mx	204	25	is	be	VBZ
cord-321013-8pkrg0mx	204	26	halted	halt	VBN
cord-321013-8pkrg0mx	204	27	.	.	.
cord-321013-8pkrg0mx	205	1	The	the	DT
cord-321013-8pkrg0mx	205	2	N	N	NNP
cord-321013-8pkrg0mx	205	3	protein	protein	NN
cord-321013-8pkrg0mx	205	4	bears	bear	VBZ
cord-321013-8pkrg0mx	205	5	a	a	DT
cord-321013-8pkrg0mx	205	6	signature	signature	NN
cord-321013-8pkrg0mx	205	7	cyclin	cyclin	NN
cord-321013-8pkrg0mx	205	8	box	box	NN
cord-321013-8pkrg0mx	205	9	-	-	HYPH
cord-321013-8pkrg0mx	205	10	binding	bind	VBG
cord-321013-8pkrg0mx	205	11	region	region	NN
cord-321013-8pkrg0mx	205	12	(	(	-LRB-
cord-321013-8pkrg0mx	205	13	RXL	rxl	NN
cord-321013-8pkrg0mx	205	14	motif	motif	NN
cord-321013-8pkrg0mx	205	15	)	)	-RRB-
cord-321013-8pkrg0mx	205	16	,	,	,
cord-321013-8pkrg0mx	205	17	can	can	MD
cord-321013-8pkrg0mx	205	18	be	be	VB
cord-321013-8pkrg0mx	205	19	phosphorylated	phosphorylate	VBN
cord-321013-8pkrg0mx	205	20	by	by	IN
cord-321013-8pkrg0mx	205	21	CDK	CDK	NNP
cord-321013-8pkrg0mx	205	22	and	and	CC
cord-321013-8pkrg0mx	205	23	is	be	VBZ
cord-321013-8pkrg0mx	205	24	therefore	therefore	RB
cord-321013-8pkrg0mx	205	25	a	a	DT
cord-321013-8pkrg0mx	205	26	substrate	substrate	NN
cord-321013-8pkrg0mx	205	27	for	for	IN
cord-321013-8pkrg0mx	205	28	the	the	DT
cord-321013-8pkrg0mx	205	29	cyclin	cyclin	NN
cord-321013-8pkrg0mx	205	30	-	-	HYPH
cord-321013-8pkrg0mx	205	31	CDK	CDK	NNP
cord-321013-8pkrg0mx	205	32	complex	complex	NN
cord-321013-8pkrg0mx	205	33	[	[	-LRB-
cord-321013-8pkrg0mx	205	34	39	39	CD
cord-321013-8pkrg0mx	205	35	]	]	-RRB-
cord-321013-8pkrg0mx	205	36	.	.	.
cord-321013-8pkrg0mx	206	1	N	N	NNP
cord-321013-8pkrg0mx	206	2	protein	protein	NN
cord-321013-8pkrg0mx	206	3	has	have	VBZ
cord-321013-8pkrg0mx	206	4	been	be	VBN
cord-321013-8pkrg0mx	206	5	shown	show	VBN
cord-321013-8pkrg0mx	206	6	to	to	TO
cord-321013-8pkrg0mx	206	7	have	have	VB
cord-321013-8pkrg0mx	206	8	an	an	DT
cord-321013-8pkrg0mx	206	9	inhibitory	inhibitory	JJ
cord-321013-8pkrg0mx	206	10	effect	effect	NN
cord-321013-8pkrg0mx	206	11	on	on	IN
cord-321013-8pkrg0mx	206	12	S	s	NN
cord-321013-8pkrg0mx	206	13	phase	phase	NN
cord-321013-8pkrg0mx	206	14	cyclins	cyclin	NNS
cord-321013-8pkrg0mx	206	15	CDK4	CDK4	NNP
cord-321013-8pkrg0mx	206	16	and	and	CC
cord-321013-8pkrg0mx	206	17	to	to	IN
cord-321013-8pkrg0mx	206	18	a	a	DT
cord-321013-8pkrg0mx	206	19	lesser	less	JJR
cord-321013-8pkrg0mx	206	20	extent	extent	NN
cord-321013-8pkrg0mx	207	1	CDK6	CDK6	NNP
cord-321013-8pkrg0mx	207	2	[	[	-LRB-
cord-321013-8pkrg0mx	207	3	39	39	CD
cord-321013-8pkrg0mx	207	4	]	]	-RRB-
cord-321013-8pkrg0mx	207	5	.	.	.
cord-321013-8pkrg0mx	208	1	The	the	DT
cord-321013-8pkrg0mx	208	2	inhibition	inhibition	NN
cord-321013-8pkrg0mx	208	3	of	of	IN
cord-321013-8pkrg0mx	208	4	kinases	kinase	NNS
cord-321013-8pkrg0mx	208	5	means	mean	VBZ
cord-321013-8pkrg0mx	208	6	that	that	IN
cord-321013-8pkrg0mx	208	7	Rb	Rb	NNP
cord-321013-8pkrg0mx	208	8	remains	remain	VBZ
cord-321013-8pkrg0mx	208	9	hypophosphorylated	hypophosphorylate	VBN
cord-321013-8pkrg0mx	208	10	and	and	CC
cord-321013-8pkrg0mx	208	11	can	can	MD
cord-321013-8pkrg0mx	208	12	not	not	RB
cord-321013-8pkrg0mx	208	13	release	release	VB
cord-321013-8pkrg0mx	208	14	E2F1	E2F1	NNP
cord-321013-8pkrg0mx	208	15	,	,	,
cord-321013-8pkrg0mx	208	16	and	and	CC
cord-321013-8pkrg0mx	208	17	the	the	DT
cord-321013-8pkrg0mx	208	18	transcription	transcription	NN
cord-321013-8pkrg0mx	208	19	of	of	IN
cord-321013-8pkrg0mx	208	20	S	s	NN
cord-321013-8pkrg0mx	208	21	phase	phase	NN
cord-321013-8pkrg0mx	208	22	genes	gene	NNS
cord-321013-8pkrg0mx	208	23	is	be	VBZ
cord-321013-8pkrg0mx	208	24	halted	halt	VBN
cord-321013-8pkrg0mx	208	25	[	[	-LRB-
cord-321013-8pkrg0mx	208	26	135	135	CD
cord-321013-8pkrg0mx	208	27	]	]	-RRB-
cord-321013-8pkrg0mx	208	28	.	.	.
cord-321013-8pkrg0mx	209	1	Similarly	similarly	RB
cord-321013-8pkrg0mx	209	2	to	to	IN
cord-321013-8pkrg0mx	209	3	MHV	MHV	NNP
cord-321013-8pkrg0mx	209	4	p28	p28	NNP
cord-321013-8pkrg0mx	209	5	,	,	,
cord-321013-8pkrg0mx	209	6	SARS	SARS	NNP
cord-321013-8pkrg0mx	209	7	-	-	HYPH
cord-321013-8pkrg0mx	209	8	CoV	CoV	NNP
cord-321013-8pkrg0mx	209	9	N	n	CD
cord-321013-8pkrg0mx	209	10	protein	protein	NN
cord-321013-8pkrg0mx	209	11	also	also	RB
cord-321013-8pkrg0mx	209	12	inhibits	inhibit	VBZ
cord-321013-8pkrg0mx	209	13	CDK2	CDK2	NNP
cord-321013-8pkrg0mx	209	14	activity	activity	NN
cord-321013-8pkrg0mx	209	15	,	,	,
cord-321013-8pkrg0mx	209	16	meaning	mean	VBG
cord-321013-8pkrg0mx	209	17	that	that	IN
cord-321013-8pkrg0mx	209	18	by	by	IN
cord-321013-8pkrg0mx	209	19	blocking	block	VBG
cord-321013-8pkrg0mx	209	20	the	the	DT
cord-321013-8pkrg0mx	209	21	activity	activity	NN
cord-321013-8pkrg0mx	209	22	of	of	IN
cord-321013-8pkrg0mx	209	23	both	both	CC
cord-321013-8pkrg0mx	209	24	G	g	NN
cord-321013-8pkrg0mx	209	25	1	1	CD
cord-321013-8pkrg0mx	209	26	and	and	CC
cord-321013-8pkrg0mx	209	27	S	S	NNP
cord-321013-8pkrg0mx	209	28	phase	phase	NN
cord-321013-8pkrg0mx	209	29	cyclins	cyclin	NNS
cord-321013-8pkrg0mx	209	30	,	,	,
cord-321013-8pkrg0mx	209	31	N	N	NNP
cord-321013-8pkrg0mx	209	32	protein	protein	NN
cord-321013-8pkrg0mx	209	33	doubly	doubly	RB
cord-321013-8pkrg0mx	209	34	ensures	ensure	VBZ
cord-321013-8pkrg0mx	209	35	the	the	DT
cord-321013-8pkrg0mx	209	36	blockage	blockage	NN
cord-321013-8pkrg0mx	209	37	of	of	IN
cord-321013-8pkrg0mx	209	38	S	S	NNP
cord-321013-8pkrg0mx	209	39	phase	phase	NN
cord-321013-8pkrg0mx	209	40	progression	progression	NN
cord-321013-8pkrg0mx	209	41	[	[	-LRB-
cord-321013-8pkrg0mx	209	42	39	39	CD
cord-321013-8pkrg0mx	209	43	]	]	-RRB-
cord-321013-8pkrg0mx	209	44	.	.	.
cord-321013-8pkrg0mx	210	1	N	N	NNP
cord-321013-8pkrg0mx	210	2	protein	protein	NN
cord-321013-8pkrg0mx	210	3	mediated	mediate	VBD
cord-321013-8pkrg0mx	210	4	inhibition	inhibition	NN
cord-321013-8pkrg0mx	210	5	of	of	IN
cord-321013-8pkrg0mx	210	6	CDK	CDK	NNP
cord-321013-8pkrg0mx	210	7	activity	activity	NN
cord-321013-8pkrg0mx	210	8	;	;	,
cord-321013-8pkrg0mx	210	9	leading	lead	VBG
cord-321013-8pkrg0mx	210	10	to	to	IN
cord-321013-8pkrg0mx	210	11	inhibition	inhibition	NN
cord-321013-8pkrg0mx	210	12	of	of	IN
cord-321013-8pkrg0mx	210	13	Rb	Rb	NNP
cord-321013-8pkrg0mx	210	14	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	210	15	,	,	,
cord-321013-8pkrg0mx	210	16	is	be	VBZ
cord-321013-8pkrg0mx	210	17	independent	independent	JJ
cord-321013-8pkrg0mx	210	18	of	of	IN
cord-321013-8pkrg0mx	210	19	CDK	CDK	NNP
cord-321013-8pkrg0mx	210	20	inhibitors	inhibitor	NNS
cord-321013-8pkrg0mx	210	21	(	(	-LRB-
cord-321013-8pkrg0mx	210	22	CDKIs	CDKIs	NNPS
cord-321013-8pkrg0mx	210	23	)	)	-RRB-
cord-321013-8pkrg0mx	210	24	such	such	JJ
cord-321013-8pkrg0mx	210	25	as	as	IN
cord-321013-8pkrg0mx	210	26	p21	p21	NN
cord-321013-8pkrg0mx	210	27	,	,	,
cord-321013-8pkrg0mx	210	28	and	and	CC
cord-321013-8pkrg0mx	210	29	so	so	RB
cord-321013-8pkrg0mx	210	30	it	-PRON-	PRP
cord-321013-8pkrg0mx	210	31	has	have	VBZ
cord-321013-8pkrg0mx	210	32	been	be	VBN
cord-321013-8pkrg0mx	210	33	suggested	suggest	VBN
cord-321013-8pkrg0mx	210	34	that	that	IN
cord-321013-8pkrg0mx	210	35	the	the	DT
cord-321013-8pkrg0mx	210	36	N	N	NNP
cord-321013-8pkrg0mx	210	37	protein	protein	NN
cord-321013-8pkrg0mx	210	38	mimics	mimic	VBZ
cord-321013-8pkrg0mx	210	39	the	the	DT
cord-321013-8pkrg0mx	210	40	role	role	NN
cord-321013-8pkrg0mx	210	41	of	of	IN
cord-321013-8pkrg0mx	210	42	CDKIs	CDKIs	NNPS
cord-321013-8pkrg0mx	210	43	by	by	IN
cord-321013-8pkrg0mx	210	44	acting	act	VBG
cord-321013-8pkrg0mx	210	45	as	as	IN
cord-321013-8pkrg0mx	210	46	a	a	DT
cord-321013-8pkrg0mx	210	47	competitive	competitive	JJ
cord-321013-8pkrg0mx	210	48	inhibitor	inhibitor	NN
cord-321013-8pkrg0mx	210	49	to	to	IN
cord-321013-8pkrg0mx	210	50	CDK4	CDK4	NNP
cord-321013-8pkrg0mx	210	51	and	and	CC
cord-321013-8pkrg0mx	210	52	CDK2	CDK2	NNP
cord-321013-8pkrg0mx	210	53	[	[	-LRB-
cord-321013-8pkrg0mx	210	54	39	39	CD
cord-321013-8pkrg0mx	210	55	]	]	-RRB-
cord-321013-8pkrg0mx	210	56	.	.	.
cord-321013-8pkrg0mx	211	1	The	the	DT
cord-321013-8pkrg0mx	211	2	ability	ability	NN
cord-321013-8pkrg0mx	211	3	of	of	IN
cord-321013-8pkrg0mx	211	4	N	n	CD
cord-321013-8pkrg0mx	211	5	protein	protein	NN
cord-321013-8pkrg0mx	211	6	to	to	TO
cord-321013-8pkrg0mx	211	7	inhibit	inhibit	VB
cord-321013-8pkrg0mx	211	8	CDK4	CDK4	NNP
cord-321013-8pkrg0mx	211	9	activity	activity	NN
cord-321013-8pkrg0mx	211	10	was	be	VBD
cord-321013-8pkrg0mx	211	11	dependent	dependent	JJ
cord-321013-8pkrg0mx	211	12	on	on	IN
cord-321013-8pkrg0mx	211	13	the	the	DT
cord-321013-8pkrg0mx	211	14	RXL	rxl	NN
cord-321013-8pkrg0mx	211	15	motif	motif	NN
cord-321013-8pkrg0mx	211	16	,	,	,
cord-321013-8pkrg0mx	211	17	whereas	whereas	IN
cord-321013-8pkrg0mx	211	18	its	-PRON-	PRP$
cord-321013-8pkrg0mx	211	19	ability	ability	NN
cord-321013-8pkrg0mx	211	20	to	to	TO
cord-321013-8pkrg0mx	211	21	inhibit	inhibit	VB
cord-321013-8pkrg0mx	211	22	CDK2	CDK2	NNP
cord-321013-8pkrg0mx	211	23	requires	require	VBZ
cord-321013-8pkrg0mx	211	24	at	at	IN
cord-321013-8pkrg0mx	211	25	least	least	RBS
cord-321013-8pkrg0mx	211	26	two	two	CD
cord-321013-8pkrg0mx	211	27	mechanisms	mechanism	NNS
cord-321013-8pkrg0mx	211	28	:	:	:
cord-321013-8pkrg0mx	211	29	the	the	DT
cord-321013-8pkrg0mx	211	30	CDK	CDK	NNP
cord-321013-8pkrg0mx	211	31	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	211	32	motif	motif	NN
cord-321013-8pkrg0mx	211	33	and	and	CC
cord-321013-8pkrg0mx	211	34	dependence	dependence	NN
cord-321013-8pkrg0mx	211	35	on	on	IN
cord-321013-8pkrg0mx	211	36	host	host	NN
cord-321013-8pkrg0mx	211	37	cell	cell	NN
cord-321013-8pkrg0mx	211	38	signaling	signal	VBG
cord-321013-8pkrg0mx	211	39	pathways	pathway	NNS
cord-321013-8pkrg0mx	211	40	[	[	-LRB-
cord-321013-8pkrg0mx	211	41	39	39	CD
cord-321013-8pkrg0mx	211	42	]	]	-RRB-
cord-321013-8pkrg0mx	211	43	.	.	.
cord-321013-8pkrg0mx	212	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	212	2	has	have	VBZ
cord-321013-8pkrg0mx	212	3	been	be	VBN
cord-321013-8pkrg0mx	212	4	postulated	postulate	VBN
cord-321013-8pkrg0mx	212	5	that	that	IN
cord-321013-8pkrg0mx	212	6	,	,	,
cord-321013-8pkrg0mx	212	7	p28-mediated	p28-mediate	VBN
cord-321013-8pkrg0mx	212	8	(	(	-LRB-
cord-321013-8pkrg0mx	212	9	MHV	MHV	NNP
cord-321013-8pkrg0mx	212	10	)	)	-RRB-
cord-321013-8pkrg0mx	212	11	and	and	CC
cord-321013-8pkrg0mx	212	12	N	n	CD
cord-321013-8pkrg0mx	212	13	protein	protein	NN
cord-321013-8pkrg0mx	212	14	-	-	HYPH
cord-321013-8pkrg0mx	212	15	mediated	mediate	VBN
cord-321013-8pkrg0mx	212	16	(	(	-LRB-
cord-321013-8pkrg0mx	212	17	SARS	SARS	NNP
cord-321013-8pkrg0mx	212	18	)	)	-RRB-
cord-321013-8pkrg0mx	212	19	blocking	block	VBG
cord-321013-8pkrg0mx	212	20	of	of	IN
cord-321013-8pkrg0mx	212	21	the	the	DT
cord-321013-8pkrg0mx	212	22	S	S	NNP
cord-321013-8pkrg0mx	212	23	phase	phase	NN
cord-321013-8pkrg0mx	212	24	,	,	,
cord-321013-8pkrg0mx	212	25	allows	allow	VBZ
cord-321013-8pkrg0mx	212	26	these	these	DT
cord-321013-8pkrg0mx	212	27	virus	virus	NN
cord-321013-8pkrg0mx	212	28	enough	enough	JJ
cord-321013-8pkrg0mx	212	29	time	time	NN
cord-321013-8pkrg0mx	212	30	to	to	TO
cord-321013-8pkrg0mx	212	31	utilize	utilize	VB
cord-321013-8pkrg0mx	212	32	the	the	DT
cord-321013-8pkrg0mx	212	33	cellular	cellular	JJ
cord-321013-8pkrg0mx	212	34	raw	raw	JJ
cord-321013-8pkrg0mx	212	35	materials	material	NNS
cord-321013-8pkrg0mx	212	36	that	that	WDT
cord-321013-8pkrg0mx	212	37	have	have	VBP
cord-321013-8pkrg0mx	212	38	been	be	VBN
cord-321013-8pkrg0mx	212	39	synthesized	synthesize	VBN
cord-321013-8pkrg0mx	212	40	ahead	ahead	RB
cord-321013-8pkrg0mx	212	41	of	of	IN
cord-321013-8pkrg0mx	212	42	the	the	DT
cord-321013-8pkrg0mx	212	43	S	S	NNP
cord-321013-8pkrg0mx	212	44	phase	phase	NN
cord-321013-8pkrg0mx	212	45	,	,	,
cord-321013-8pkrg0mx	212	46	for	for	IN
cord-321013-8pkrg0mx	212	47	replication	replication	NN
cord-321013-8pkrg0mx	212	48	of	of	IN
cord-321013-8pkrg0mx	212	49	its	-PRON-	PRP$
cord-321013-8pkrg0mx	212	50	genome	genome	NN
cord-321013-8pkrg0mx	212	51	,	,	,
cord-321013-8pkrg0mx	212	52	as	as	RB
cord-321013-8pkrg0mx	212	53	well	well	RB
cord-321013-8pkrg0mx	212	54	as	as	IN
cord-321013-8pkrg0mx	212	55	for	for	IN
cord-321013-8pkrg0mx	212	56	assembly	assembly	NN
cord-321013-8pkrg0mx	212	57	and	and	CC
cord-321013-8pkrg0mx	212	58	budding	budding	NN
cord-321013-8pkrg0mx	212	59	of	of	IN
cord-321013-8pkrg0mx	212	60	progeny	progeny	NN
cord-321013-8pkrg0mx	212	61	particles	particle	NNS
cord-321013-8pkrg0mx	212	62	[	[	-LRB-
cord-321013-8pkrg0mx	212	63	142	142	CD
cord-321013-8pkrg0mx	212	64	]	]	-RRB-
cord-321013-8pkrg0mx	212	65	.	.	.
cord-321013-8pkrg0mx	213	1	These	these	DT
cord-321013-8pkrg0mx	213	2	studies	study	NNS
cord-321013-8pkrg0mx	213	3	provide	provide	VBP
cord-321013-8pkrg0mx	213	4	evidence	evidence	NN
cord-321013-8pkrg0mx	213	5	that	that	IN
cord-321013-8pkrg0mx	213	6	even	even	RB
cord-321013-8pkrg0mx	213	7	within	within	IN
cord-321013-8pkrg0mx	213	8	the	the	DT
cord-321013-8pkrg0mx	213	9	CoV	cov	NN
cord-321013-8pkrg0mx	213	10	family	family	NN
cord-321013-8pkrg0mx	213	11	,	,	,
cord-321013-8pkrg0mx	213	12	different	different	JJ
cord-321013-8pkrg0mx	213	13	proteins	protein	NNS
cord-321013-8pkrg0mx	213	14	can	can	MD
cord-321013-8pkrg0mx	213	15	deregulate	deregulate	VB
cord-321013-8pkrg0mx	213	16	the	the	DT
cord-321013-8pkrg0mx	213	17	cell	cell	NN
cord-321013-8pkrg0mx	213	18	cycle	cycle	NN
cord-321013-8pkrg0mx	213	19	and	and	CC
cord-321013-8pkrg0mx	213	20	that	that	IN
cord-321013-8pkrg0mx	213	21	those	those	DT
cord-321013-8pkrg0mx	213	22	proteins	protein	NNS
cord-321013-8pkrg0mx	213	23	,	,	,
cord-321013-8pkrg0mx	213	24	in	in	IN
cord-321013-8pkrg0mx	213	25	the	the	DT
cord-321013-8pkrg0mx	213	26	case	case	NN
cord-321013-8pkrg0mx	213	27	of	of	IN
cord-321013-8pkrg0mx	213	28	SARS	SARS	NNP
cord-321013-8pkrg0mx	213	29	-	-	HYPH
cord-321013-8pkrg0mx	213	30	N	N	NNP
cord-321013-8pkrg0mx	213	31	protein	protein	NN
cord-321013-8pkrg0mx	213	32	,	,	,
cord-321013-8pkrg0mx	213	33	can	can	MD
cord-321013-8pkrg0mx	213	34	employ	employ	VB
cord-321013-8pkrg0mx	213	35	multiple	multiple	JJ
cord-321013-8pkrg0mx	213	36	mechanisms	mechanism	NNS
cord-321013-8pkrg0mx	213	37	to	to	TO
cord-321013-8pkrg0mx	213	38	achieve	achieve	VB
cord-321013-8pkrg0mx	213	39	this	this	DT
cord-321013-8pkrg0mx	213	40	.	.	.
cord-321013-8pkrg0mx	214	1	In	in	IN
cord-321013-8pkrg0mx	214	2	response	response	NN
cord-321013-8pkrg0mx	214	3	to	to	IN
cord-321013-8pkrg0mx	214	4	environmental	environmental	JJ
cord-321013-8pkrg0mx	214	5	stress	stress	NN
cord-321013-8pkrg0mx	214	6	,	,	,
cord-321013-8pkrg0mx	214	7	eukaryotic	eukaryotic	JJ
cord-321013-8pkrg0mx	214	8	cells	cell	NNS
cord-321013-8pkrg0mx	214	9	reprogram	reprogram	VBP
cord-321013-8pkrg0mx	214	10	their	-PRON-	PRP$
cord-321013-8pkrg0mx	214	11	mRNA	mrna	NN
cord-321013-8pkrg0mx	214	12	metabolism	metabolism	NN
cord-321013-8pkrg0mx	214	13	to	to	TO
cord-321013-8pkrg0mx	214	14	adapt	adapt	VB
cord-321013-8pkrg0mx	214	15	to	to	IN
cord-321013-8pkrg0mx	214	16	stress	stress	NN
cord-321013-8pkrg0mx	214	17	-	-	HYPH
cord-321013-8pkrg0mx	214	18	induced	induce	VBN
cord-321013-8pkrg0mx	214	19	damage	damage	NN
cord-321013-8pkrg0mx	214	20	.	.	.
cord-321013-8pkrg0mx	215	1	Translationally	translationally	RB
cord-321013-8pkrg0mx	215	2	stalled	stall	VBD
cord-321013-8pkrg0mx	215	3	mRNAs	mRNAs	NNPS
cord-321013-8pkrg0mx	215	4	together	together	RB
cord-321013-8pkrg0mx	215	5	with	with	IN
cord-321013-8pkrg0mx	215	6	a	a	DT
cord-321013-8pkrg0mx	215	7	number	number	NN
cord-321013-8pkrg0mx	215	8	of	of	IN
cord-321013-8pkrg0mx	215	9	translational	translational	JJ
cord-321013-8pkrg0mx	215	10	initiation	initiation	NN
cord-321013-8pkrg0mx	215	11	factors	factor	NNS
cord-321013-8pkrg0mx	215	12	and	and	CC
cord-321013-8pkrg0mx	215	13	RNA	rna	NN
cord-321013-8pkrg0mx	215	14	-	-	HYPH
cord-321013-8pkrg0mx	215	15	binding	bind	VBG
cord-321013-8pkrg0mx	215	16	proteins	protein	NNS
cord-321013-8pkrg0mx	215	17	are	be	VBP
cord-321013-8pkrg0mx	215	18	selectively	selectively	RB
cord-321013-8pkrg0mx	215	19	deposited	deposit	VBN
cord-321013-8pkrg0mx	215	20	in	in	IN
cord-321013-8pkrg0mx	215	21	cytoplasmic	cytoplasmic	JJ
cord-321013-8pkrg0mx	215	22	stress	stress	NN
cord-321013-8pkrg0mx	215	23	granules	granule	NNS
cord-321013-8pkrg0mx	215	24	(	(	-LRB-
cord-321013-8pkrg0mx	215	25	SGs	SGs	NNP
cord-321013-8pkrg0mx	215	26	)	)	-RRB-
cord-321013-8pkrg0mx	216	1	[	[	-LRB-
cord-321013-8pkrg0mx	216	2	143	143	CD
cord-321013-8pkrg0mx	216	3	]	]	-RRB-
cord-321013-8pkrg0mx	216	4	.	.	.
cord-321013-8pkrg0mx	217	1	CoVs	CoVs	NNP
cord-321013-8pkrg0mx	217	2	,	,	,
cord-321013-8pkrg0mx	217	3	like	like	IN
cord-321013-8pkrg0mx	217	4	many	many	JJ
cord-321013-8pkrg0mx	217	5	other	other	JJ
cord-321013-8pkrg0mx	217	6	viruses	virus	NNS
cord-321013-8pkrg0mx	217	7	,	,	,
cord-321013-8pkrg0mx	217	8	induce	induce	VB
cord-321013-8pkrg0mx	217	9	host	host	NN
cord-321013-8pkrg0mx	217	10	translational	translational	JJ
cord-321013-8pkrg0mx	217	11	shutoff	shutoff	NN
cord-321013-8pkrg0mx	217	12	,	,	,
cord-321013-8pkrg0mx	217	13	while	while	IN
cord-321013-8pkrg0mx	217	14	maintaining	maintain	VBG
cord-321013-8pkrg0mx	217	15	synthesis	synthesis	NN
cord-321013-8pkrg0mx	217	16	of	of	IN
cord-321013-8pkrg0mx	217	17	their	-PRON-	PRP$
cord-321013-8pkrg0mx	217	18	own	own	JJ
cord-321013-8pkrg0mx	217	19	gene	gene	NN
cord-321013-8pkrg0mx	217	20	products	product	NNS
cord-321013-8pkrg0mx	217	21	,	,	,
cord-321013-8pkrg0mx	217	22	as	as	IN
cord-321013-8pkrg0mx	217	23	a	a	DT
cord-321013-8pkrg0mx	217	24	means	means	NN
cord-321013-8pkrg0mx	217	25	to	to	TO
cord-321013-8pkrg0mx	217	26	interfere	interfere	VB
cord-321013-8pkrg0mx	217	27	with	with	IN
cord-321013-8pkrg0mx	217	28	cellular	cellular	JJ
cord-321013-8pkrg0mx	217	29	defense	defense	NN
cord-321013-8pkrg0mx	217	30	mechanisms	mechanism	NNS
cord-321013-8pkrg0mx	217	31	[	[	-LRB-
cord-321013-8pkrg0mx	217	32	144	144	CD
cord-321013-8pkrg0mx	217	33	]	]	-RRB-
cord-321013-8pkrg0mx	217	34	.	.	.
cord-321013-8pkrg0mx	218	1	MHV	MHV	NNP
cord-321013-8pkrg0mx	218	2	-	-	:
cord-321013-8pkrg0mx	218	3	induces	induce	VBZ
cord-321013-8pkrg0mx	218	4	a	a	DT
cord-321013-8pkrg0mx	218	5	host	host	NN
cord-321013-8pkrg0mx	218	6	translational	translational	JJ
cord-321013-8pkrg0mx	218	7	shutoff	shutoff	NN
cord-321013-8pkrg0mx	218	8	that	that	WDT
cord-321013-8pkrg0mx	218	9	is	be	VBZ
cord-321013-8pkrg0mx	218	10	reminiscent	reminiscent	JJ
cord-321013-8pkrg0mx	218	11	of	of	IN
cord-321013-8pkrg0mx	218	12	a	a	DT
cord-321013-8pkrg0mx	218	13	cellular	cellular	JJ
cord-321013-8pkrg0mx	218	14	stress	stress	NN
cord-321013-8pkrg0mx	218	15	response	response	NN
cord-321013-8pkrg0mx	218	16	;	;	:
cord-321013-8pkrg0mx	218	17	SGs	SGs	NNP
cord-321013-8pkrg0mx	218	18	appear	appear	VBP
cord-321013-8pkrg0mx	218	19	,	,	,
cord-321013-8pkrg0mx	218	20	numerous	numerous	JJ
cord-321013-8pkrg0mx	218	21	mRNAs	mRNAs	NNPS
cord-321013-8pkrg0mx	218	22	including	include	VBG
cord-321013-8pkrg0mx	218	23	protein	protein	NN
cord-321013-8pkrg0mx	218	24	translation	translation	NN
cord-321013-8pkrg0mx	218	25	-	-	HYPH
cord-321013-8pkrg0mx	218	26	related	relate	VBN
cord-321013-8pkrg0mx	218	27	factors	factor	NNS
cord-321013-8pkrg0mx	218	28	are	be	VBP
cord-321013-8pkrg0mx	218	29	downregulated	downregulate	VBN
cord-321013-8pkrg0mx	218	30	and	and	CC
cord-321013-8pkrg0mx	218	31	levels	level	NNS
cord-321013-8pkrg0mx	218	32	of	of	IN
cord-321013-8pkrg0mx	218	33	phosphorylated	phosphorylated	JJ
cord-321013-8pkrg0mx	218	34	translation	translation	NN
cord-321013-8pkrg0mx	218	35	initiation	initiation	NN
cord-321013-8pkrg0mx	218	36	factors	factor	NNS
cord-321013-8pkrg0mx	218	37	increase	increase	VBP
cord-321013-8pkrg0mx	218	38	[	[	-LRB-
cord-321013-8pkrg0mx	218	39	145	145	CD
cord-321013-8pkrg0mx	218	40	]	]	-RRB-
cord-321013-8pkrg0mx	218	41	.	.	.
cord-321013-8pkrg0mx	219	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	219	2	is	be	VBZ
cord-321013-8pkrg0mx	219	3	important	important	JJ
cord-321013-8pkrg0mx	219	4	to	to	TO
cord-321013-8pkrg0mx	219	5	remember	remember	VB
cord-321013-8pkrg0mx	219	6	,	,	,
cord-321013-8pkrg0mx	219	7	though	though	IN
cord-321013-8pkrg0mx	219	8	that	that	IN
cord-321013-8pkrg0mx	219	9	this	this	DT
cord-321013-8pkrg0mx	219	10	translational	translational	JJ
cord-321013-8pkrg0mx	219	11	shutoff	shutoff	NN
cord-321013-8pkrg0mx	219	12	could	could	MD
cord-321013-8pkrg0mx	219	13	also	also	RB
cord-321013-8pkrg0mx	219	14	simply	simply	RB
cord-321013-8pkrg0mx	219	15	be	be	VB
cord-321013-8pkrg0mx	219	16	the	the	DT
cord-321013-8pkrg0mx	219	17	host	host	NN
cord-321013-8pkrg0mx	219	18	cell	cell	NN
cord-321013-8pkrg0mx	219	19	's	's	POS
cord-321013-8pkrg0mx	219	20	response	response	NN
cord-321013-8pkrg0mx	219	21	to	to	IN
cord-321013-8pkrg0mx	219	22	the	the	DT
cord-321013-8pkrg0mx	219	23	infection	infection	NN
cord-321013-8pkrg0mx	219	24	.	.	.
cord-321013-8pkrg0mx	220	1	In	in	IN
cord-321013-8pkrg0mx	220	2	SARS	SARS	NNP
cord-321013-8pkrg0mx	220	3	-	-	HYPH
cord-321013-8pkrg0mx	220	4	infected	infect	VBN
cord-321013-8pkrg0mx	220	5	HeLa	HeLa	NNP
cord-321013-8pkrg0mx	220	6	cells	cell	NNS
cord-321013-8pkrg0mx	220	7	that	that	WDT
cord-321013-8pkrg0mx	220	8	are	be	VBP
cord-321013-8pkrg0mx	220	9	exposed	expose	VBN
cord-321013-8pkrg0mx	220	10	to	to	IN
cord-321013-8pkrg0mx	220	11	arsenite	arsenite	JJ
cord-321013-8pkrg0mx	220	12	treatment	treatment	NN
cord-321013-8pkrg0mx	220	13	,	,	,
cord-321013-8pkrg0mx	220	14	N	N	NNP
cord-321013-8pkrg0mx	220	15	protein	protein	NN
cord-321013-8pkrg0mx	220	16	translocates	translocate	NNS
cord-321013-8pkrg0mx	220	17	to	to	IN
cord-321013-8pkrg0mx	220	18	cytoplasmic	cytoplasmic	JJ
cord-321013-8pkrg0mx	220	19	SGs	SGs	NNP
cord-321013-8pkrg0mx	220	20	where	where	WRB
cord-321013-8pkrg0mx	220	21	it	-PRON-	PRP
cord-321013-8pkrg0mx	220	22	colocalizes	colocalize	VBZ
cord-321013-8pkrg0mx	220	23	with	with	IN
cord-321013-8pkrg0mx	220	24	poly(A)-binding	poly(A)-binding	NNP
cord-321013-8pkrg0mx	220	25	protein	protein	NN
cord-321013-8pkrg0mx	220	26	1	1	CD
cord-321013-8pkrg0mx	220	27	(	(	-LRB-
cord-321013-8pkrg0mx	220	28	PARB	PARB	NNP
cord-321013-8pkrg0mx	220	29	)	)	-RRB-
cord-321013-8pkrg0mx	220	30	and	and	CC
cord-321013-8pkrg0mx	220	31	transiently	transiently	RB
cord-321013-8pkrg0mx	220	32	expressed	express	VBD
cord-321013-8pkrg0mx	220	33	TIA-1	TIA-1	NNP
cord-321013-8pkrg0mx	220	34	[	[	-LRB-
cord-321013-8pkrg0mx	220	35	38	38	CD
cord-321013-8pkrg0mx	220	36	]	]	-RRB-
cord-321013-8pkrg0mx	220	37	,	,	,
cord-321013-8pkrg0mx	220	38	both	both	DT
cord-321013-8pkrg0mx	220	39	of	of	IN
cord-321013-8pkrg0mx	220	40	which	which	WDT
cord-321013-8pkrg0mx	220	41	are	be	VBP
cord-321013-8pkrg0mx	220	42	components	component	NNS
cord-321013-8pkrg0mx	220	43	of	of	IN
cord-321013-8pkrg0mx	220	44	SGs	SGs	NNP
cord-321013-8pkrg0mx	220	45	[	[	-LRB-
cord-321013-8pkrg0mx	220	46	143	143	CD
cord-321013-8pkrg0mx	220	47	]	]	-RRB-
cord-321013-8pkrg0mx	220	48	.	.	.
cord-321013-8pkrg0mx	221	1	This	this	DT
cord-321013-8pkrg0mx	221	2	localization	localization	NN
cord-321013-8pkrg0mx	221	3	and	and	CC
cord-321013-8pkrg0mx	221	4	pattern	pattern	NN
cord-321013-8pkrg0mx	221	5	was	be	VBD
cord-321013-8pkrg0mx	221	6	enhanced	enhance	VBN
cord-321013-8pkrg0mx	221	7	when	when	WRB
cord-321013-8pkrg0mx	221	8	the	the	DT
cord-321013-8pkrg0mx	221	9	protein	protein	NN
cord-321013-8pkrg0mx	221	10	was	be	VBD
cord-321013-8pkrg0mx	221	11	hypophosphorylated	hypophosphorylate	VBN
cord-321013-8pkrg0mx	221	12	(	(	-LRB-
cord-321013-8pkrg0mx	221	13	NΔRS	NΔRS	NNP
cord-321013-8pkrg0mx	221	14	)	)	-RRB-
cord-321013-8pkrg0mx	221	15	,	,	,
cord-321013-8pkrg0mx	221	16	perhaps	perhaps	RB
cord-321013-8pkrg0mx	221	17	because	because	IN
cord-321013-8pkrg0mx	221	18	NΔRS	NΔRS	NNP
cord-321013-8pkrg0mx	221	19	induced	induce	VBD
cord-321013-8pkrg0mx	221	20	larger	large	JJR
cord-321013-8pkrg0mx	221	21	ribonucleoprotein	ribonucleoprotein	NN
cord-321013-8pkrg0mx	221	22	(	(	-LRB-
cord-321013-8pkrg0mx	221	23	RNP	RNP	NNP
cord-321013-8pkrg0mx	221	24	)	)	-RRB-
cord-321013-8pkrg0mx	221	25	complex	complex	JJ
cord-321013-8pkrg0mx	221	26	formation	formation	NN
cord-321013-8pkrg0mx	221	27	[	[	-LRB-
cord-321013-8pkrg0mx	221	28	38	38	CD
cord-321013-8pkrg0mx	221	29	]	]	-RRB-
cord-321013-8pkrg0mx	221	30	.	.	.
cord-321013-8pkrg0mx	222	1	The	the	DT
cord-321013-8pkrg0mx	222	2	sequestration	sequestration	NN
cord-321013-8pkrg0mx	222	3	of	of	IN
cord-321013-8pkrg0mx	222	4	N	n	CD
cord-321013-8pkrg0mx	222	5	protein	protein	NN
cord-321013-8pkrg0mx	222	6	in	in	IN
cord-321013-8pkrg0mx	222	7	SGs	SGs	NNP
cord-321013-8pkrg0mx	222	8	possibly	possibly	RB
cord-321013-8pkrg0mx	222	9	indicates	indicate	VBZ
cord-321013-8pkrg0mx	222	10	a	a	DT
cord-321013-8pkrg0mx	222	11	role	role	NN
cord-321013-8pkrg0mx	222	12	in	in	IN
cord-321013-8pkrg0mx	222	13	translational	translational	JJ
cord-321013-8pkrg0mx	222	14	suppression	suppression	NN
cord-321013-8pkrg0mx	222	15	.	.	.
cord-321013-8pkrg0mx	223	1	The	the	DT
cord-321013-8pkrg0mx	223	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	223	3	protein	protein	NN
cord-321013-8pkrg0mx	223	4	of	of	IN
cord-321013-8pkrg0mx	223	5	both	both	CC
cord-321013-8pkrg0mx	223	6	porcine	porcine	JJ
cord-321013-8pkrg0mx	223	7	and	and	CC
cord-321013-8pkrg0mx	223	8	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	223	9	syndrome	syndrome	NN
cord-321013-8pkrg0mx	223	10	and	and	CC
cord-321013-8pkrg0mx	223	11	rubella	rubella	NN
cord-321013-8pkrg0mx	223	12	virus	virus	NN
cord-321013-8pkrg0mx	223	13	also	also	RB
cord-321013-8pkrg0mx	223	14	interact	interact	VBP
cord-321013-8pkrg0mx	223	15	with	with	IN
cord-321013-8pkrg0mx	223	16	PARB	PARB	NNP
cord-321013-8pkrg0mx	223	17	,	,	,
cord-321013-8pkrg0mx	223	18	which	which	WDT
cord-321013-8pkrg0mx	223	19	promotes	promote	VBZ
cord-321013-8pkrg0mx	223	20	protein	protein	NN
cord-321013-8pkrg0mx	223	21	synthesis	synthesis	NN
cord-321013-8pkrg0mx	223	22	by	by	IN
cord-321013-8pkrg0mx	223	23	circularizing	circularize	VBG
cord-321013-8pkrg0mx	223	24	mRNAs	mrnas	XX
cord-321013-8pkrg0mx	223	25	,	,	,
cord-321013-8pkrg0mx	223	26	and	and	CC
cord-321013-8pkrg0mx	223	27	inhibit	inhibit	VB
cord-321013-8pkrg0mx	223	28	host	host	NN
cord-321013-8pkrg0mx	223	29	protein	protein	NN
cord-321013-8pkrg0mx	223	30	synthesis	synthesis	NN
cord-321013-8pkrg0mx	223	31	by	by	IN
cord-321013-8pkrg0mx	223	32	sequestration	sequestration	NN
cord-321013-8pkrg0mx	223	33	of	of	IN
cord-321013-8pkrg0mx	223	34	PARB	PARB	NNP
cord-321013-8pkrg0mx	223	35	through	through	IN
cord-321013-8pkrg0mx	223	36	a	a	DT
cord-321013-8pkrg0mx	223	37	stoichiometric	stoichiometric	JJ
cord-321013-8pkrg0mx	223	38	mechanism	mechanism	NN
cord-321013-8pkrg0mx	223	39	[	[	-LRB-
cord-321013-8pkrg0mx	223	40	146	146	CD
cord-321013-8pkrg0mx	223	41	,	,	,
cord-321013-8pkrg0mx	223	42	147	147	CD
cord-321013-8pkrg0mx	223	43	]	]	-RRB-
cord-321013-8pkrg0mx	223	44	.	.	.
cord-321013-8pkrg0mx	224	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	224	2	has	have	VBZ
cord-321013-8pkrg0mx	224	3	been	be	VBN
cord-321013-8pkrg0mx	224	4	proposed	propose	VBN
cord-321013-8pkrg0mx	224	5	that	that	IN
cord-321013-8pkrg0mx	224	6	,	,	,
cord-321013-8pkrg0mx	224	7	at	at	IN
cord-321013-8pkrg0mx	224	8	least	least	JJS
cord-321013-8pkrg0mx	224	9	in	in	IN
cord-321013-8pkrg0mx	224	10	the	the	DT
cord-321013-8pkrg0mx	224	11	rubella	rubella	NN
cord-321013-8pkrg0mx	224	12	virus	virus	NN
cord-321013-8pkrg0mx	224	13	,	,	,
cord-321013-8pkrg0mx	224	14	that	that	IN
cord-321013-8pkrg0mx	224	15	N	n	NN
cord-321013-8pkrg0mx	224	16	-	-	HYPH
cord-321013-8pkrg0mx	224	17	dependent	dependent	JJ
cord-321013-8pkrg0mx	224	18	inhibition	inhibition	NN
cord-321013-8pkrg0mx	224	19	of	of	IN
cord-321013-8pkrg0mx	224	20	translation	translation	NN
cord-321013-8pkrg0mx	224	21	via	via	IN
cord-321013-8pkrg0mx	224	22	PARB	PARB	NNP
cord-321013-8pkrg0mx	224	23	binding	binding	NN
cord-321013-8pkrg0mx	224	24	may	may	MD
cord-321013-8pkrg0mx	224	25	facilitate	facilitate	VB
cord-321013-8pkrg0mx	224	26	the	the	DT
cord-321013-8pkrg0mx	224	27	switch	switch	NN
cord-321013-8pkrg0mx	224	28	from	from	IN
cord-321013-8pkrg0mx	224	29	viral	viral	JJ
cord-321013-8pkrg0mx	224	30	translation	translation	NN
cord-321013-8pkrg0mx	224	31	to	to	IN
cord-321013-8pkrg0mx	224	32	packaging	package	VBG
cord-321013-8pkrg0mx	224	33	RNA	RNA	NNP
cord-321013-8pkrg0mx	224	34	into	into	IN
cord-321013-8pkrg0mx	224	35	nucleocapsids	nucleocapsid	NNS
cord-321013-8pkrg0mx	224	36	[	[	-LRB-
cord-321013-8pkrg0mx	224	37	146	146	CD
cord-321013-8pkrg0mx	224	38	]	]	-RRB-
cord-321013-8pkrg0mx	224	39	.	.	.
cord-321013-8pkrg0mx	225	1	More	more	RBR
cord-321013-8pkrg0mx	225	2	specifically	specifically	RB
cord-321013-8pkrg0mx	225	3	,	,	,
cord-321013-8pkrg0mx	225	4	binding	bind	VBG
cord-321013-8pkrg0mx	225	5	of	of	IN
cord-321013-8pkrg0mx	225	6	the	the	DT
cord-321013-8pkrg0mx	225	7	capsid	capsid	NN
cord-321013-8pkrg0mx	225	8	to	to	IN
cord-321013-8pkrg0mx	225	9	PARB	PARB	NNP
cord-321013-8pkrg0mx	225	10	late	late	RB
cord-321013-8pkrg0mx	225	11	in	in	IN
cord-321013-8pkrg0mx	225	12	the	the	DT
cord-321013-8pkrg0mx	225	13	virus	virus	NN
cord-321013-8pkrg0mx	225	14	cycle	cycle	NN
cord-321013-8pkrg0mx	225	15	,	,	,
cord-321013-8pkrg0mx	225	16	when	when	WRB
cord-321013-8pkrg0mx	225	17	the	the	DT
cord-321013-8pkrg0mx	225	18	levels	level	NNS
cord-321013-8pkrg0mx	225	19	of	of	IN
cord-321013-8pkrg0mx	225	20	newly	newly	RB
cord-321013-8pkrg0mx	225	21	synthesized	synthesize	VBN
cord-321013-8pkrg0mx	225	22	genomes	genome	NNS
cord-321013-8pkrg0mx	225	23	and	and	CC
cord-321013-8pkrg0mx	225	24	viral	viral	JJ
cord-321013-8pkrg0mx	225	25	proteins	protein	NNS
cord-321013-8pkrg0mx	225	26	are	be	VBP
cord-321013-8pkrg0mx	225	27	high	high	JJ
cord-321013-8pkrg0mx	225	28	,	,	,
cord-321013-8pkrg0mx	225	29	and	and	CC
cord-321013-8pkrg0mx	225	30	there	there	EX
cord-321013-8pkrg0mx	225	31	is	be	VBZ
cord-321013-8pkrg0mx	225	32	little	little	JJ
cord-321013-8pkrg0mx	225	33	need	need	NN
cord-321013-8pkrg0mx	225	34	for	for	IN
cord-321013-8pkrg0mx	225	35	additional	additional	JJ
cord-321013-8pkrg0mx	225	36	replicase	replicase	NN
cord-321013-8pkrg0mx	225	37	components	component	NNS
cord-321013-8pkrg0mx	225	38	,	,	,
cord-321013-8pkrg0mx	225	39	could	could	MD
cord-321013-8pkrg0mx	225	40	prevent	prevent	VB
cord-321013-8pkrg0mx	225	41	recruitment	recruitment	NN
cord-321013-8pkrg0mx	225	42	of	of	IN
cord-321013-8pkrg0mx	225	43	ribosomes	ribosome	NNS
cord-321013-8pkrg0mx	225	44	to	to	IN
cord-321013-8pkrg0mx	225	45	the	the	DT
cord-321013-8pkrg0mx	225	46	nascent	nascent	JJ
cord-321013-8pkrg0mx	225	47	40S	40s	CD
cord-321013-8pkrg0mx	225	48	RNA	RNA	NNP
cord-321013-8pkrg0mx	225	49	.	.	.
cord-321013-8pkrg0mx	226	1	This	this	DT
cord-321013-8pkrg0mx	226	2	scenario	scenario	NN
cord-321013-8pkrg0mx	226	3	would	would	MD
cord-321013-8pkrg0mx	226	4	favour	favour	VB
cord-321013-8pkrg0mx	226	5	packaging	packaging	NN
cord-321013-8pkrg0mx	226	6	of	of	IN
cord-321013-8pkrg0mx	226	7	the	the	DT
cord-321013-8pkrg0mx	226	8	40S	40s	CD
cord-321013-8pkrg0mx	226	9	genomic	genomic	JJ
cord-321013-8pkrg0mx	226	10	RNA	RNA	NNP
cord-321013-8pkrg0mx	226	11	into	into	IN
cord-321013-8pkrg0mx	226	12	nucleocapsids	nucleocapsid	NNS
cord-321013-8pkrg0mx	226	13	[	[	-LRB-
cord-321013-8pkrg0mx	226	14	146	146	CD
cord-321013-8pkrg0mx	226	15	]	]	-RRB-
cord-321013-8pkrg0mx	226	16	.	.	.
cord-321013-8pkrg0mx	227	1	Considering	consider	VBG
cord-321013-8pkrg0mx	227	2	that	that	IN
cord-321013-8pkrg0mx	227	3	SARS	SARS	NNP
cord-321013-8pkrg0mx	227	4	-	-	HYPH
cord-321013-8pkrg0mx	227	5	N	N	NNP
cord-321013-8pkrg0mx	227	6	and	and	CC
cord-321013-8pkrg0mx	227	7	MHV	MHV	NNP
cord-321013-8pkrg0mx	227	8	-	-	HYPH
cord-321013-8pkrg0mx	227	9	N	N	NNP
cord-321013-8pkrg0mx	227	10	protein	protein	NN
cord-321013-8pkrg0mx	227	11	has	have	VBZ
cord-321013-8pkrg0mx	227	12	been	be	VBN
cord-321013-8pkrg0mx	227	13	shown	show	VBN
cord-321013-8pkrg0mx	227	14	to	to	TO
cord-321013-8pkrg0mx	227	15	interact	interact	VB
cord-321013-8pkrg0mx	227	16	with	with	IN
cord-321013-8pkrg0mx	227	17	the	the	DT
cord-321013-8pkrg0mx	227	18	PARB	PARB	NNP
cord-321013-8pkrg0mx	227	19	hnRNP	hnRNP	NNP
cord-321013-8pkrg0mx	227	20	-	-	HYPH
cord-321013-8pkrg0mx	227	21	A1	a1	NN
cord-321013-8pkrg0mx	227	22	[	[	-LRB-
cord-321013-8pkrg0mx	227	23	41	41	CD
cord-321013-8pkrg0mx	227	24	,	,	,
cord-321013-8pkrg0mx	227	25	148	148	CD
cord-321013-8pkrg0mx	227	26	]	]	-RRB-
cord-321013-8pkrg0mx	227	27	,	,	,
cord-321013-8pkrg0mx	227	28	it	-PRON-	PRP
cord-321013-8pkrg0mx	227	29	is	be	VBZ
cord-321013-8pkrg0mx	227	30	possible	possible	JJ
cord-321013-8pkrg0mx	227	31	that	that	IN
cord-321013-8pkrg0mx	227	32	the	the	DT
cord-321013-8pkrg0mx	227	33	N	N	NNP
cord-321013-8pkrg0mx	227	34	-	-	HYPH
cord-321013-8pkrg0mx	227	35	PARB	PARB	NNP
cord-321013-8pkrg0mx	227	36	interaction	interaction	NN
cord-321013-8pkrg0mx	227	37	also	also	RB
cord-321013-8pkrg0mx	227	38	acts	act	VBZ
cord-321013-8pkrg0mx	227	39	as	as	IN
cord-321013-8pkrg0mx	227	40	a	a	DT
cord-321013-8pkrg0mx	227	41	switch	switch	NN
cord-321013-8pkrg0mx	227	42	that	that	WDT
cord-321013-8pkrg0mx	227	43	redirects	redirect	VBZ
cord-321013-8pkrg0mx	227	44	viral	viral	JJ
cord-321013-8pkrg0mx	227	45	activity	activity	NN
cord-321013-8pkrg0mx	227	46	from	from	IN
cord-321013-8pkrg0mx	227	47	RNA	RNA	NNP
cord-321013-8pkrg0mx	227	48	synthesis	synthesis	NN
cord-321013-8pkrg0mx	227	49	to	to	IN
cord-321013-8pkrg0mx	227	50	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	227	51	formation	formation	NN
cord-321013-8pkrg0mx	227	52	.	.	.
cord-321013-8pkrg0mx	228	1	The	the	DT
cord-321013-8pkrg0mx	228	2	translational	translational	JJ
cord-321013-8pkrg0mx	228	3	suppressive	suppressive	JJ
cord-321013-8pkrg0mx	228	4	effect	effect	NN
cord-321013-8pkrg0mx	228	5	of	of	IN
cord-321013-8pkrg0mx	228	6	the	the	DT
cord-321013-8pkrg0mx	228	7	N	N	NNP
cord-321013-8pkrg0mx	228	8	protein	protein	NN
cord-321013-8pkrg0mx	228	9	could	could	MD
cord-321013-8pkrg0mx	228	10	also	also	RB
cord-321013-8pkrg0mx	228	11	be	be	VB
cord-321013-8pkrg0mx	228	12	through	through	IN
cord-321013-8pkrg0mx	228	13	its	-PRON-	PRP$
cord-321013-8pkrg0mx	228	14	CTD	CTD	NNP
cord-321013-8pkrg0mx	228	15	interaction	interaction	NN
cord-321013-8pkrg0mx	228	16	with	with	IN
cord-321013-8pkrg0mx	228	17	elongation	elongation	NN
cord-321013-8pkrg0mx	228	18	factor	factor	NN
cord-321013-8pkrg0mx	228	19	1α	1α	CD
cord-321013-8pkrg0mx	228	20	(	(	-LRB-
cord-321013-8pkrg0mx	228	21	EF1α	EF1α	NNP
cord-321013-8pkrg0mx	228	22	)	)	-RRB-
cord-321013-8pkrg0mx	228	23	,	,	,
cord-321013-8pkrg0mx	228	24	a	a	DT
cord-321013-8pkrg0mx	228	25	major	major	JJ
cord-321013-8pkrg0mx	228	26	translational	translational	JJ
cord-321013-8pkrg0mx	228	27	factor	factor	NN
cord-321013-8pkrg0mx	228	28	in	in	IN
cord-321013-8pkrg0mx	228	29	mammalian	mammalian	JJ
cord-321013-8pkrg0mx	228	30	cells	cell	NNS
cord-321013-8pkrg0mx	228	31	[	[	-LRB-
cord-321013-8pkrg0mx	228	32	75	75	CD
cord-321013-8pkrg0mx	228	33	]	]	-RRB-
cord-321013-8pkrg0mx	228	34	.	.	.
cord-321013-8pkrg0mx	229	1	N	n	CD
cord-321013-8pkrg0mx	229	2	protein	protein	NN
cord-321013-8pkrg0mx	229	3	of	of	IN
cord-321013-8pkrg0mx	229	4	SARS	SARS	NNP
cord-321013-8pkrg0mx	229	5	-	-	HYPH
cord-321013-8pkrg0mx	229	6	CoV	CoV	NNP
cord-321013-8pkrg0mx	229	7	binds	bind	VBZ
cord-321013-8pkrg0mx	229	8	directly	directly	RB
cord-321013-8pkrg0mx	229	9	to	to	IN
cord-321013-8pkrg0mx	229	10	and	and	CC
cord-321013-8pkrg0mx	229	11	induces	induce	VBZ
cord-321013-8pkrg0mx	229	12	aggregation	aggregation	NN
cord-321013-8pkrg0mx	229	13	of	of	IN
cord-321013-8pkrg0mx	229	14	EF1α	EF1α	NNP
cord-321013-8pkrg0mx	229	15	,	,	,
cord-321013-8pkrg0mx	229	16	resulting	result	VBG
cord-321013-8pkrg0mx	229	17	in	in	IN
cord-321013-8pkrg0mx	229	18	inhibition	inhibition	NN
cord-321013-8pkrg0mx	229	19	of	of	IN
cord-321013-8pkrg0mx	229	20	protein	protein	NN
cord-321013-8pkrg0mx	229	21	translation	translation	NN
cord-321013-8pkrg0mx	229	22	[	[	-LRB-
cord-321013-8pkrg0mx	229	23	75	75	CD
cord-321013-8pkrg0mx	229	24	]	]	-RRB-
cord-321013-8pkrg0mx	229	25	.	.	.
cord-321013-8pkrg0mx	230	1	Moreover	moreover	RB
cord-321013-8pkrg0mx	230	2	,	,	,
cord-321013-8pkrg0mx	230	3	EF1α	EF1α	NNP
cord-321013-8pkrg0mx	230	4	is	be	VBZ
cord-321013-8pkrg0mx	230	5	a	a	DT
cord-321013-8pkrg0mx	230	6	multifunctional	multifunctional	JJ
cord-321013-8pkrg0mx	230	7	protein	protein	NN
cord-321013-8pkrg0mx	230	8	and	and	CC
cord-321013-8pkrg0mx	230	9	has	have	VBZ
cord-321013-8pkrg0mx	230	10	unconventional	unconventional	JJ
cord-321013-8pkrg0mx	230	11	functions	function	NNS
cord-321013-8pkrg0mx	230	12	related	relate	VBN
cord-321013-8pkrg0mx	230	13	to	to	IN
cord-321013-8pkrg0mx	230	14	its	-PRON-	PRP$
cord-321013-8pkrg0mx	230	15	association	association	NN
cord-321013-8pkrg0mx	230	16	with	with	IN
cord-321013-8pkrg0mx	230	17	the	the	DT
cord-321013-8pkrg0mx	230	18	cytoskeleton	cytoskeleton	NN
cord-321013-8pkrg0mx	230	19	,	,	,
cord-321013-8pkrg0mx	230	20	including	include	VBG
cord-321013-8pkrg0mx	230	21	interaction	interaction	NN
cord-321013-8pkrg0mx	230	22	with	with	IN
cord-321013-8pkrg0mx	230	23	filamentous	filamentous	JJ
cord-321013-8pkrg0mx	230	24	(	(	-LRB-
cord-321013-8pkrg0mx	230	25	F	F	NNP
cord-321013-8pkrg0mx	230	26	)	)	-RRB-
cord-321013-8pkrg0mx	230	27	actin	actin	NN
cord-321013-8pkrg0mx	230	28	,	,	,
cord-321013-8pkrg0mx	230	29	promotion	promotion	NN
cord-321013-8pkrg0mx	230	30	of	of	IN
cord-321013-8pkrg0mx	230	31	F	F	NNP
cord-321013-8pkrg0mx	230	32	actin	actin	NN
cord-321013-8pkrg0mx	230	33	bundling	bundling	NN
cord-321013-8pkrg0mx	230	34	and	and	CC
cord-321013-8pkrg0mx	230	35	formation	formation	NN
cord-321013-8pkrg0mx	230	36	of	of	IN
cord-321013-8pkrg0mx	230	37	a	a	DT
cord-321013-8pkrg0mx	230	38	contractile	contractile	JJ
cord-321013-8pkrg0mx	230	39	ring	ring	NN
cord-321013-8pkrg0mx	230	40	during	during	IN
cord-321013-8pkrg0mx	230	41	cytokinesis	cytokinesis	NN
cord-321013-8pkrg0mx	230	42	[	[	-LRB-
cord-321013-8pkrg0mx	230	43	149	149	CD
cord-321013-8pkrg0mx	230	44	]	]	-RRB-
cord-321013-8pkrg0mx	231	1	[	[	-LRB-
cord-321013-8pkrg0mx	231	2	150	150	CD
cord-321013-8pkrg0mx	231	3	]	]	-RRB-
cord-321013-8pkrg0mx	231	4	[	[	-LRB-
cord-321013-8pkrg0mx	231	5	151	151	CD
cord-321013-8pkrg0mx	231	6	]	]	-RRB-
cord-321013-8pkrg0mx	231	7	[	[	-LRB-
cord-321013-8pkrg0mx	231	8	152	152	CD
cord-321013-8pkrg0mx	231	9	]	]	-RRB-
cord-321013-8pkrg0mx	231	10	.	.	.
cord-321013-8pkrg0mx	232	1	N	N	NNP
cord-321013-8pkrg0mx	232	2	-	-	HYPH
cord-321013-8pkrg0mx	232	3	EF1α	EF1α	NNP
cord-321013-8pkrg0mx	232	4	therefore	therefore	RB
cord-321013-8pkrg0mx	232	5	blocks	block	VBZ
cord-321013-8pkrg0mx	232	6	EF1α	EF1α	NNP
cord-321013-8pkrg0mx	232	7	-	-	HYPH
cord-321013-8pkrg0mx	232	8	mediated	mediate	VBN
cord-321013-8pkrg0mx	232	9	F	F	NNP
cord-321013-8pkrg0mx	232	10	actin	actin	NN
cord-321013-8pkrg0mx	232	11	bundling	bundling	NN
cord-321013-8pkrg0mx	232	12	and	and	CC
cord-321013-8pkrg0mx	232	13	the	the	DT
cord-321013-8pkrg0mx	232	14	formation	formation	NN
cord-321013-8pkrg0mx	232	15	of	of	IN
cord-321013-8pkrg0mx	232	16	the	the	DT
cord-321013-8pkrg0mx	232	17	contractile	contractile	JJ
cord-321013-8pkrg0mx	232	18	ring	ring	NN
cord-321013-8pkrg0mx	232	19	,	,	,
cord-321013-8pkrg0mx	232	20	leading	lead	VBG
cord-321013-8pkrg0mx	232	21	to	to	IN
cord-321013-8pkrg0mx	232	22	the	the	DT
cord-321013-8pkrg0mx	232	23	formation	formation	NN
cord-321013-8pkrg0mx	232	24	of	of	IN
cord-321013-8pkrg0mx	232	25	multinucleated	multinucleate	VBN
cord-321013-8pkrg0mx	232	26	cells	cell	NNS
cord-321013-8pkrg0mx	232	27	by	by	IN
cord-321013-8pkrg0mx	232	28	inhibiting	inhibit	VBG
cord-321013-8pkrg0mx	232	29	cytokinesis	cytokinesis	NN
cord-321013-8pkrg0mx	232	30	[	[	-LRB-
cord-321013-8pkrg0mx	232	31	75	75	CD
cord-321013-8pkrg0mx	232	32	]	]	-RRB-
cord-321013-8pkrg0mx	232	33	.	.	.
cord-321013-8pkrg0mx	233	1	Multinucleated	multinucleated	JJ
cord-321013-8pkrg0mx	233	2	syncytia	syncytia	NN
cord-321013-8pkrg0mx	233	3	of	of	IN
cord-321013-8pkrg0mx	233	4	macrophages	macrophage	NNS
cord-321013-8pkrg0mx	233	5	have	have	VBP
cord-321013-8pkrg0mx	233	6	been	be	VBN
cord-321013-8pkrg0mx	233	7	observed	observe	VBN
cord-321013-8pkrg0mx	233	8	in	in	IN
cord-321013-8pkrg0mx	233	9	late	late	JJ
cord-321013-8pkrg0mx	233	10	-	-	HYPH
cord-321013-8pkrg0mx	233	11	phase	phase	NN
cord-321013-8pkrg0mx	233	12	SARS	SARS	NNP
cord-321013-8pkrg0mx	233	13	-	-	HYPH
cord-321013-8pkrg0mx	233	14	CoV	CoV	NNP
cord-321013-8pkrg0mx	233	15	but	but	CC
cord-321013-8pkrg0mx	233	16	not	not	RB
cord-321013-8pkrg0mx	233	17	in	in	IN
cord-321013-8pkrg0mx	233	18	other	other	JJ
cord-321013-8pkrg0mx	233	19	CoV	cov	NN
cord-321013-8pkrg0mx	233	20	-	-	HYPH
cord-321013-8pkrg0mx	233	21	infected	infect	VBN
cord-321013-8pkrg0mx	233	22	patients	patient	NNS
cord-321013-8pkrg0mx	233	23	[	[	-LRB-
cord-321013-8pkrg0mx	233	24	153	153	CD
cord-321013-8pkrg0mx	233	25	]	]	-RRB-
cord-321013-8pkrg0mx	233	26	.	.	.
cord-321013-8pkrg0mx	234	1	The	the	DT
cord-321013-8pkrg0mx	234	2	N	n	CD
cord-321013-8pkrg0mx	234	3	protein	protein	NN
cord-321013-8pkrg0mx	234	4	of	of	IN
cord-321013-8pkrg0mx	234	5	hCoV-229E	hCoV-229E	NNP
cord-321013-8pkrg0mx	234	6	also	also	RB
cord-321013-8pkrg0mx	234	7	binds	bind	VBZ
cord-321013-8pkrg0mx	234	8	to	to	IN
cord-321013-8pkrg0mx	234	9	EF1α	EF1α	NNP
cord-321013-8pkrg0mx	234	10	,	,	,
cord-321013-8pkrg0mx	234	11	but	but	CC
cord-321013-8pkrg0mx	234	12	with	with	IN
cord-321013-8pkrg0mx	234	13	significantly	significantly	RB
cord-321013-8pkrg0mx	234	14	lower	low	JJR
cord-321013-8pkrg0mx	234	15	affinity	affinity	NN
cord-321013-8pkrg0mx	234	16	than	than	IN
cord-321013-8pkrg0mx	234	17	SARS	SARS	NNP
cord-321013-8pkrg0mx	234	18	-	-	HYPH
cord-321013-8pkrg0mx	234	19	CoV	CoV	NNP
cord-321013-8pkrg0mx	234	20	N	N	NNP
cord-321013-8pkrg0mx	234	21	,	,	,
cord-321013-8pkrg0mx	234	22	and	and	CC
cord-321013-8pkrg0mx	234	23	induces	induce	VBZ
cord-321013-8pkrg0mx	234	24	multinucleation	multinucleation	NN
cord-321013-8pkrg0mx	234	25	much	much	RB
cord-321013-8pkrg0mx	234	26	more	more	RBR
cord-321013-8pkrg0mx	234	27	slowly	slowly	RB
cord-321013-8pkrg0mx	234	28	in	in	IN
cord-321013-8pkrg0mx	234	29	a	a	DT
cord-321013-8pkrg0mx	234	30	substantially	substantially	RB
cord-321013-8pkrg0mx	234	31	smaller	small	JJR
cord-321013-8pkrg0mx	234	32	fraction	fraction	NN
cord-321013-8pkrg0mx	234	33	of	of	IN
cord-321013-8pkrg0mx	234	34	transfected	transfecte	VBN
cord-321013-8pkrg0mx	234	35	cells	cell	NNS
cord-321013-8pkrg0mx	234	36	[	[	-LRB-
cord-321013-8pkrg0mx	234	37	75	75	CD
cord-321013-8pkrg0mx	234	38	]	]	-RRB-
cord-321013-8pkrg0mx	234	39	.	.	.
cord-321013-8pkrg0mx	235	1	In	in	IN
cord-321013-8pkrg0mx	235	2	addition	addition	NN
cord-321013-8pkrg0mx	235	3	,	,	,
cord-321013-8pkrg0mx	235	4	N	n	CD
cord-321013-8pkrg0mx	235	5	-	-	HYPH
cord-321013-8pkrg0mx	235	6	protein	protein	NN
cord-321013-8pkrg0mx	235	7	mediated	mediate	VBN
cord-321013-8pkrg0mx	235	8	inhibition	inhibition	NN
cord-321013-8pkrg0mx	235	9	of	of	IN
cord-321013-8pkrg0mx	235	10	cytokinesis	cytokinesis	NN
cord-321013-8pkrg0mx	235	11	leads	lead	VBZ
cord-321013-8pkrg0mx	235	12	to	to	IN
cord-321013-8pkrg0mx	235	13	inhibition	inhibition	NN
cord-321013-8pkrg0mx	235	14	of	of	IN
cord-321013-8pkrg0mx	235	15	cell	cell	NN
cord-321013-8pkrg0mx	235	16	proliferation	proliferation	NN
cord-321013-8pkrg0mx	235	17	in	in	IN
cord-321013-8pkrg0mx	235	18	human	human	JJ
cord-321013-8pkrg0mx	235	19	peripheral	peripheral	JJ
cord-321013-8pkrg0mx	235	20	blood	blood	NN
cord-321013-8pkrg0mx	235	21	lymphocytes	lymphocyte	NNS
cord-321013-8pkrg0mx	235	22	(	(	-LRB-
cord-321013-8pkrg0mx	235	23	PBLs	pbl	NNS
cord-321013-8pkrg0mx	235	24	)	)	-RRB-
cord-321013-8pkrg0mx	235	25	[	[	-LRB-
cord-321013-8pkrg0mx	235	26	75	75	CD
cord-321013-8pkrg0mx	235	27	]	]	-RRB-
cord-321013-8pkrg0mx	235	28	.	.	.
cord-321013-8pkrg0mx	236	1	Since	since	IN
cord-321013-8pkrg0mx	236	2	actively	actively	RB
cord-321013-8pkrg0mx	236	3	dividing	divide	VBG
cord-321013-8pkrg0mx	236	4	lymphocytes	lymphocyte	NNS
cord-321013-8pkrg0mx	236	5	are	be	VBP
cord-321013-8pkrg0mx	236	6	a	a	DT
cord-321013-8pkrg0mx	236	7	major	major	JJ
cord-321013-8pkrg0mx	236	8	cell	cell	NN
cord-321013-8pkrg0mx	236	9	target	target	NN
cord-321013-8pkrg0mx	236	10	of	of	IN
cord-321013-8pkrg0mx	236	11	SARS	SARS	NNP
cord-321013-8pkrg0mx	236	12	-	-	HYPH
cord-321013-8pkrg0mx	236	13	CoV	CoV	NNP
cord-321013-8pkrg0mx	236	14	[	[	-LRB-
cord-321013-8pkrg0mx	236	15	154	154	CD
cord-321013-8pkrg0mx	236	16	]	]	-RRB-
cord-321013-8pkrg0mx	236	17	,	,	,
cord-321013-8pkrg0mx	236	18	SARS	SARS	NNP
cord-321013-8pkrg0mx	236	19	-	-	HYPH
cord-321013-8pkrg0mx	236	20	CoV	CoV	NNP
cord-321013-8pkrg0mx	236	21	N	N	NNP
cord-321013-8pkrg0mx	236	22	may	may	MD
cord-321013-8pkrg0mx	236	23	decelerate	decelerate	VB
cord-321013-8pkrg0mx	236	24	lymphocyte	lymphocyte	NN
cord-321013-8pkrg0mx	236	25	proliferation	proliferation	NN
cord-321013-8pkrg0mx	236	26	and	and	CC
cord-321013-8pkrg0mx	236	27	therefore	therefore	RB
cord-321013-8pkrg0mx	236	28	interfere	interfere	VB
cord-321013-8pkrg0mx	236	29	with	with	IN
cord-321013-8pkrg0mx	236	30	immune	immune	JJ
cord-321013-8pkrg0mx	236	31	system	system	NN
cord-321013-8pkrg0mx	236	32	function	function	NN
cord-321013-8pkrg0mx	236	33	[	[	-LRB-
cord-321013-8pkrg0mx	236	34	75	75	CD
cord-321013-8pkrg0mx	236	35	]	]	-RRB-
cord-321013-8pkrg0mx	236	36	.	.	.
cord-321013-8pkrg0mx	237	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	237	2	-	-	HYPH
cord-321013-8pkrg0mx	237	3	N	N	NNP
cord-321013-8pkrg0mx	237	4	protein	protein	NN
cord-321013-8pkrg0mx	237	5	has	have	VBZ
cord-321013-8pkrg0mx	237	6	also	also	RB
cord-321013-8pkrg0mx	237	7	been	be	VBN
cord-321013-8pkrg0mx	237	8	shown	show	VBN
cord-321013-8pkrg0mx	237	9	to	to	TO
cord-321013-8pkrg0mx	237	10	cause	cause	VB
cord-321013-8pkrg0mx	237	11	cytoskeletal	cytoskeletal	JJ
cord-321013-8pkrg0mx	237	12	changes	change	NNS
cord-321013-8pkrg0mx	237	13	in	in	IN
cord-321013-8pkrg0mx	237	14	response	response	NN
cord-321013-8pkrg0mx	237	15	to	to	IN
cord-321013-8pkrg0mx	237	16	a	a	DT
cord-321013-8pkrg0mx	237	17	different	different	JJ
cord-321013-8pkrg0mx	237	18	type	type	NN
cord-321013-8pkrg0mx	237	19	of	of	IN
cord-321013-8pkrg0mx	237	20	cell	cell	NN
cord-321013-8pkrg0mx	237	21	stress	stress	NN
cord-321013-8pkrg0mx	237	22	,	,	,
cord-321013-8pkrg0mx	237	23	namely	namely	RB
cord-321013-8pkrg0mx	237	24	serum	serum	NN
cord-321013-8pkrg0mx	237	25	deprivation	deprivation	NN
cord-321013-8pkrg0mx	237	26	[	[	-LRB-
cord-321013-8pkrg0mx	237	27	155	155	CD
cord-321013-8pkrg0mx	237	28	]	]	-RRB-
cord-321013-8pkrg0mx	237	29	.	.	.
cord-321013-8pkrg0mx	238	1	N	N	NNP
cord-321013-8pkrg0mx	238	2	protein	protein	NN
cord-321013-8pkrg0mx	238	3	induces	induce	VBZ
cord-321013-8pkrg0mx	238	4	actin	actin	NN
cord-321013-8pkrg0mx	238	5	reorganization	reorganization	NN
cord-321013-8pkrg0mx	238	6	in	in	IN
cord-321013-8pkrg0mx	238	7	COS-1	COS-1	NNP
cord-321013-8pkrg0mx	238	8	monkey	monkey	NN
cord-321013-8pkrg0mx	238	9	kidney	kidney	NN
cord-321013-8pkrg0mx	238	10	cells	cell	NNS
cord-321013-8pkrg0mx	238	11	by	by	IN
cord-321013-8pkrg0mx	238	12	down	down	RB
cord-321013-8pkrg0mx	238	13	regulating	regulate	VBG
cord-321013-8pkrg0mx	238	14	focal	focal	JJ
cord-321013-8pkrg0mx	238	15	adhesion	adhesion	NN
cord-321013-8pkrg0mx	238	16	kinase	kinase	NN
cord-321013-8pkrg0mx	238	17	and	and	CC
cord-321013-8pkrg0mx	238	18	fibronectin	fibronectin	NN
cord-321013-8pkrg0mx	238	19	via	via	IN
cord-321013-8pkrg0mx	238	20	p38	p38	NNP
cord-321013-8pkrg0mx	238	21	MAPK	MAPK	NNP
cord-321013-8pkrg0mx	238	22	pathway	pathway	NN
cord-321013-8pkrg0mx	238	23	activation	activation	NN
cord-321013-8pkrg0mx	238	24	[	[	-LRB-
cord-321013-8pkrg0mx	238	25	155	155	CD
cord-321013-8pkrg0mx	238	26	]	]	-RRB-
cord-321013-8pkrg0mx	238	27	.	.	.
cord-321013-8pkrg0mx	239	1	N	N	NNP
cord-321013-8pkrg0mx	239	2	protein	protein	NN
cord-321013-8pkrg0mx	239	3	plays	play	VBZ
cord-321013-8pkrg0mx	239	4	an	an	DT
cord-321013-8pkrg0mx	239	5	important	important	JJ
cord-321013-8pkrg0mx	239	6	role	role	NN
cord-321013-8pkrg0mx	239	7	in	in	IN
cord-321013-8pkrg0mx	239	8	viral	viral	JJ
cord-321013-8pkrg0mx	239	9	pathogenesis	pathogenesis	NN
cord-321013-8pkrg0mx	239	10	since	since	IN
cord-321013-8pkrg0mx	239	11	anti	anti	JJ
cord-321013-8pkrg0mx	239	12	-	-	JJ
cord-321013-8pkrg0mx	239	13	N	n	JJ
cord-321013-8pkrg0mx	239	14	monoclonal	monoclonal	JJ
cord-321013-8pkrg0mx	239	15	antibodies	antibody	NNS
cord-321013-8pkrg0mx	239	16	protect	protect	VBP
cord-321013-8pkrg0mx	239	17	mice	mouse	NNS
cord-321013-8pkrg0mx	239	18	from	from	IN
cord-321013-8pkrg0mx	239	19	lethal	lethal	JJ
cord-321013-8pkrg0mx	239	20	infection	infection	NN
cord-321013-8pkrg0mx	239	21	of	of	IN
cord-321013-8pkrg0mx	239	22	JMHV	JMHV	NNP
cord-321013-8pkrg0mx	239	23	[	[	-LRB-
cord-321013-8pkrg0mx	239	24	156	156	CD
cord-321013-8pkrg0mx	239	25	]	]	-RRB-
cord-321013-8pkrg0mx	239	26	.	.	.
cord-321013-8pkrg0mx	240	1	Coronaviruses	coronaviruse	NNS
cord-321013-8pkrg0mx	240	2	seem	seem	VBP
cord-321013-8pkrg0mx	240	3	to	to	TO
cord-321013-8pkrg0mx	240	4	have	have	VB
cord-321013-8pkrg0mx	240	5	developed	develop	VBN
cord-321013-8pkrg0mx	240	6	mechanisms	mechanism	NNS
cord-321013-8pkrg0mx	240	7	to	to	TO
cord-321013-8pkrg0mx	240	8	overcome	overcome	VB
cord-321013-8pkrg0mx	240	9	the	the	DT
cord-321013-8pkrg0mx	240	10	host	host	NN
cord-321013-8pkrg0mx	240	11	innate	innate	JJ
cord-321013-8pkrg0mx	240	12	immune	immune	JJ
cord-321013-8pkrg0mx	240	13	response	response	NN
cord-321013-8pkrg0mx	240	14	,	,	,
cord-321013-8pkrg0mx	240	15	including	include	VBG
cord-321013-8pkrg0mx	240	16	the	the	DT
cord-321013-8pkrg0mx	240	17	interferon	interferon	NN
cord-321013-8pkrg0mx	240	18	response	response	NN
cord-321013-8pkrg0mx	240	19	,	,	,
cord-321013-8pkrg0mx	240	20	a	a	DT
cord-321013-8pkrg0mx	240	21	major	major	JJ
cord-321013-8pkrg0mx	240	22	component	component	NN
cord-321013-8pkrg0mx	240	23	of	of	IN
cord-321013-8pkrg0mx	240	24	innate	innate	JJ
cord-321013-8pkrg0mx	240	25	immunity	immunity	NN
cord-321013-8pkrg0mx	240	26	.	.	.
cord-321013-8pkrg0mx	241	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	241	2	-	-	HYPH
cord-321013-8pkrg0mx	241	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	241	4	infected	infect	VBN
cord-321013-8pkrg0mx	241	5	cells	cell	NNS
cord-321013-8pkrg0mx	241	6	do	do	VBP
cord-321013-8pkrg0mx	241	7	not	not	RB
cord-321013-8pkrg0mx	241	8	allow	allow	VB
cord-321013-8pkrg0mx	241	9	production	production	NN
cord-321013-8pkrg0mx	241	10	of	of	IN
cord-321013-8pkrg0mx	241	11	interferon	interferon	NN
cord-321013-8pkrg0mx	241	12	and	and	CC
cord-321013-8pkrg0mx	241	13	so	so	RB
cord-321013-8pkrg0mx	241	14	it	-PRON-	PRP
cord-321013-8pkrg0mx	241	15	seems	seem	VBZ
cord-321013-8pkrg0mx	241	16	likely	likely	JJ
cord-321013-8pkrg0mx	241	17	that	that	IN
cord-321013-8pkrg0mx	241	18	SARS	SARS	NNP
cord-321013-8pkrg0mx	241	19	-	-	HYPH
cord-321013-8pkrg0mx	241	20	CoV	CoV	NNP
cord-321013-8pkrg0mx	241	21	,	,	,
cord-321013-8pkrg0mx	241	22	like	like	IN
cord-321013-8pkrg0mx	241	23	many	many	JJ
cord-321013-8pkrg0mx	241	24	other	other	JJ
cord-321013-8pkrg0mx	241	25	viruses	virus	NNS
cord-321013-8pkrg0mx	241	26	,	,	,
cord-321013-8pkrg0mx	241	27	has	have	VBZ
cord-321013-8pkrg0mx	241	28	developed	develop	VBN
cord-321013-8pkrg0mx	241	29	mechanisms	mechanism	NNS
cord-321013-8pkrg0mx	241	30	to	to	TO
cord-321013-8pkrg0mx	241	31	subvert	subvert	VB
cord-321013-8pkrg0mx	241	32	the	the	DT
cord-321013-8pkrg0mx	241	33	interferon	interferon	NN
cord-321013-8pkrg0mx	241	34	response	response	NN
cord-321013-8pkrg0mx	241	35	[	[	-LRB-
cord-321013-8pkrg0mx	241	36	157	157	CD
cord-321013-8pkrg0mx	241	37	]	]	-RRB-
cord-321013-8pkrg0mx	241	38	.	.	.
cord-321013-8pkrg0mx	242	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	242	2	-	-	HYPH
cord-321013-8pkrg0mx	242	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	242	4	N	n	CD
cord-321013-8pkrg0mx	242	5	protein	protein	NN
cord-321013-8pkrg0mx	242	6	is	be	VBZ
cord-321013-8pkrg0mx	242	7	one	one	CD
cord-321013-8pkrg0mx	242	8	of	of	IN
cord-321013-8pkrg0mx	242	9	three	three	CD
cord-321013-8pkrg0mx	242	10	β	β	NN
cord-321013-8pkrg0mx	242	11	interferon	interferon	NN
cord-321013-8pkrg0mx	242	12	(	(	-LRB-
cord-321013-8pkrg0mx	242	13	IFβ	IFβ	NNS
cord-321013-8pkrg0mx	242	14	)	)	-RRB-
cord-321013-8pkrg0mx	242	15	antagonists	antagonist	NNS
cord-321013-8pkrg0mx	242	16	,	,	,
cord-321013-8pkrg0mx	242	17	with	with	IN
cord-321013-8pkrg0mx	242	18	ORF3b	ORF3b	NNP
cord-321013-8pkrg0mx	242	19	and	and	CC
cord-321013-8pkrg0mx	242	20	ORF6	ORF6	NNP
cord-321013-8pkrg0mx	242	21	being	be	VBG
cord-321013-8pkrg0mx	242	22	the	the	DT
cord-321013-8pkrg0mx	242	23	other	other	JJ
cord-321013-8pkrg0mx	242	24	two	two	CD
cord-321013-8pkrg0mx	242	25	,	,	,
cord-321013-8pkrg0mx	242	26	and	and	CC
cord-321013-8pkrg0mx	242	27	inhibition	inhibition	NN
cord-321013-8pkrg0mx	242	28	of	of	IN
cord-321013-8pkrg0mx	242	29	IFβ	IFβ	NNS
cord-321013-8pkrg0mx	242	30	synthesis	synthesis	NN
cord-321013-8pkrg0mx	242	31	by	by	IN
cord-321013-8pkrg0mx	242	32	N	n	CD
cord-321013-8pkrg0mx	242	33	protein	protein	NN
cord-321013-8pkrg0mx	242	34	is	be	VBZ
cord-321013-8pkrg0mx	242	35	due	due	JJ
cord-321013-8pkrg0mx	242	36	to	to	IN
cord-321013-8pkrg0mx	242	37	inhibition	inhibition	NN
cord-321013-8pkrg0mx	242	38	of	of	IN
cord-321013-8pkrg0mx	242	39	IRF-3	IRF-3	NNP
cord-321013-8pkrg0mx	242	40	and	and	CC
cord-321013-8pkrg0mx	242	41	NF	NF	NNP
cord-321013-8pkrg0mx	242	42	-	-	HYPH
cord-321013-8pkrg0mx	242	43	kB	kB	NNP
cord-321013-8pkrg0mx	242	44	,	,	,
cord-321013-8pkrg0mx	242	45	two	two	CD
cord-321013-8pkrg0mx	242	46	of	of	IN
cord-321013-8pkrg0mx	242	47	the	the	DT
cord-321013-8pkrg0mx	242	48	transcription	transcription	NN
cord-321013-8pkrg0mx	242	49	factors	factor	NNS
cord-321013-8pkrg0mx	242	50	required	require	VBN
cord-321013-8pkrg0mx	242	51	for	for	IN
cord-321013-8pkrg0mx	242	52	IF	if	NN
cord-321013-8pkrg0mx	242	53	gene	gene	NN
cord-321013-8pkrg0mx	242	54	expression	expression	NN
cord-321013-8pkrg0mx	242	55	[	[	-LRB-
cord-321013-8pkrg0mx	242	56	158	158	CD
cord-321013-8pkrg0mx	242	57	]	]	-RRB-
cord-321013-8pkrg0mx	242	58	.	.	.
cord-321013-8pkrg0mx	243	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	243	2	-	-	HYPH
cord-321013-8pkrg0mx	243	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	243	4	N	n	CD
cord-321013-8pkrg0mx	243	5	protein	protein	NN
cord-321013-8pkrg0mx	243	6	inhibits	inhibit	VBZ
cord-321013-8pkrg0mx	243	7	the	the	DT
cord-321013-8pkrg0mx	243	8	synthesis	synthesis	NN
cord-321013-8pkrg0mx	243	9	of	of	IN
cord-321013-8pkrg0mx	243	10	type-1	type-1	NNP
cord-321013-8pkrg0mx	243	11	interferon	interferon	NN
cord-321013-8pkrg0mx	243	12	(	(	-LRB-
cord-321013-8pkrg0mx	243	13	1FN	1fn	CD
cord-321013-8pkrg0mx	243	14	)	)	-RRB-
cord-321013-8pkrg0mx	243	15	and	and	CC
cord-321013-8pkrg0mx	244	1	the	the	DT
cord-321013-8pkrg0mx	244	2	CTD	CTD	NNP
cord-321013-8pkrg0mx	244	3	of	of	IN
cord-321013-8pkrg0mx	244	4	N	N	NNP
cord-321013-8pkrg0mx	244	5	has	have	VBZ
cord-321013-8pkrg0mx	244	6	been	be	VBN
cord-321013-8pkrg0mx	244	7	shown	show	VBN
cord-321013-8pkrg0mx	244	8	to	to	TO
cord-321013-8pkrg0mx	244	9	be	be	VB
cord-321013-8pkrg0mx	244	10	critical	critical	JJ
cord-321013-8pkrg0mx	244	11	for	for	IN
cord-321013-8pkrg0mx	244	12	antagonism	antagonism	NN
cord-321013-8pkrg0mx	244	13	of	of	IN
cord-321013-8pkrg0mx	244	14	1FN	1fn	CD
cord-321013-8pkrg0mx	244	15	induction	induction	NN
cord-321013-8pkrg0mx	244	16	[	[	-LRB-
cord-321013-8pkrg0mx	244	17	159	159	CD
cord-321013-8pkrg0mx	244	18	]	]	-RRB-
cord-321013-8pkrg0mx	244	19	.	.	.
cord-321013-8pkrg0mx	245	1	This	this	DT
cord-321013-8pkrg0mx	245	2	inhibition	inhibition	NN
cord-321013-8pkrg0mx	245	3	of	of	IN
cord-321013-8pkrg0mx	245	4	the	the	DT
cord-321013-8pkrg0mx	245	5	interferon	interferon	NN
cord-321013-8pkrg0mx	245	6	response	response	NN
cord-321013-8pkrg0mx	245	7	likely	likely	RB
cord-321013-8pkrg0mx	245	8	contributes	contribute	VBZ
cord-321013-8pkrg0mx	245	9	to	to	IN
cord-321013-8pkrg0mx	245	10	the	the	DT
cord-321013-8pkrg0mx	245	11	pathogenesis	pathogenesis	NN
cord-321013-8pkrg0mx	245	12	of	of	IN
cord-321013-8pkrg0mx	245	13	SARS	SARS	NNP
cord-321013-8pkrg0mx	245	14	-	-	HYPH
cord-321013-8pkrg0mx	245	15	CoV.	CoV.	NNP
cord-321013-8pkrg0mx	245	16	CoV	cov	NN
cord-321013-8pkrg0mx	245	17	infection	infection	NN
cord-321013-8pkrg0mx	245	18	is	be	VBZ
cord-321013-8pkrg0mx	245	19	likely	likely	JJ
cord-321013-8pkrg0mx	245	20	to	to	TO
cord-321013-8pkrg0mx	245	21	activate	activate	VB
cord-321013-8pkrg0mx	245	22	a	a	DT
cord-321013-8pkrg0mx	245	23	diversity	diversity	NN
cord-321013-8pkrg0mx	245	24	of	of	IN
cord-321013-8pkrg0mx	245	25	host	host	NN
cord-321013-8pkrg0mx	245	26	cell	cell	NN
cord-321013-8pkrg0mx	245	27	signal	signal	NN
cord-321013-8pkrg0mx	245	28	transduction	transduction	NN
cord-321013-8pkrg0mx	245	29	pathways	pathway	NNS
cord-321013-8pkrg0mx	245	30	and	and	CC
cord-321013-8pkrg0mx	245	31	kinases	kinase	NNS
cord-321013-8pkrg0mx	245	32	,	,	,
cord-321013-8pkrg0mx	245	33	which	which	WDT
cord-321013-8pkrg0mx	245	34	would	would	MD
cord-321013-8pkrg0mx	245	35	lead	lead	VB
cord-321013-8pkrg0mx	245	36	to	to	IN
cord-321013-8pkrg0mx	245	37	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	245	38	of	of	IN
cord-321013-8pkrg0mx	245	39	N	n	CD
cord-321013-8pkrg0mx	245	40	protein	protein	NN
cord-321013-8pkrg0mx	245	41	[	[	-LRB-
cord-321013-8pkrg0mx	245	42	160	160	CD
cord-321013-8pkrg0mx	245	43	]	]	-RRB-
cord-321013-8pkrg0mx	245	44	.	.	.
cord-321013-8pkrg0mx	246	1	N	n	NN
cord-321013-8pkrg0mx	246	2	protein	protein	NN
cord-321013-8pkrg0mx	246	3	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	246	4	would	would	MD
cord-321013-8pkrg0mx	246	5	therefore	therefore	RB
cord-321013-8pkrg0mx	246	6	only	only	RB
cord-321013-8pkrg0mx	246	7	occur	occur	VB
cord-321013-8pkrg0mx	246	8	at	at	IN
cord-321013-8pkrg0mx	246	9	a	a	DT
cord-321013-8pkrg0mx	246	10	relatively	relatively	RB
cord-321013-8pkrg0mx	246	11	late	late	JJ
cord-321013-8pkrg0mx	246	12	stage	stage	NN
cord-321013-8pkrg0mx	246	13	of	of	IN
cord-321013-8pkrg0mx	246	14	the	the	DT
cord-321013-8pkrg0mx	246	15	viral	viral	JJ
cord-321013-8pkrg0mx	246	16	cell	cell	NN
cord-321013-8pkrg0mx	246	17	cycle	cycle	NN
cord-321013-8pkrg0mx	246	18	and	and	CC
cord-321013-8pkrg0mx	246	19	may	may	MD
cord-321013-8pkrg0mx	246	20	explain	explain	VB
cord-321013-8pkrg0mx	246	21	why	why	WRB
cord-321013-8pkrg0mx	246	22	more	more	RBR
cord-321013-8pkrg0mx	246	23	phosphorylated	phosphorylated	JJ
cord-321013-8pkrg0mx	246	24	N	n	CD
cord-321013-8pkrg0mx	246	25	protein	protein	NN
cord-321013-8pkrg0mx	246	26	is	be	VBZ
cord-321013-8pkrg0mx	246	27	incorporated	incorporate	VBN
cord-321013-8pkrg0mx	246	28	into	into	IN
cord-321013-8pkrg0mx	246	29	IBV	IBV	NNP
cord-321013-8pkrg0mx	246	30	virions	virion	NNS
cord-321013-8pkrg0mx	246	31	[	[	-LRB-
cord-321013-8pkrg0mx	246	32	161	161	CD
cord-321013-8pkrg0mx	246	33	]	]	-RRB-
cord-321013-8pkrg0mx	246	34	.	.	.
cord-321013-8pkrg0mx	247	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	247	2	has	have	VBZ
cord-321013-8pkrg0mx	247	3	been	be	VBN
cord-321013-8pkrg0mx	247	4	demonstrated	demonstrate	VBN
cord-321013-8pkrg0mx	247	5	that	that	IN
cord-321013-8pkrg0mx	247	6	the	the	DT
cord-321013-8pkrg0mx	247	7	SARS	SARS	NNP
cord-321013-8pkrg0mx	247	8	-	-	HYPH
cord-321013-8pkrg0mx	247	9	CoV	CoV	NNP
cord-321013-8pkrg0mx	247	10	N	n	CD
cord-321013-8pkrg0mx	247	11	protein	protein	NN
cord-321013-8pkrg0mx	247	12	can	can	MD
cord-321013-8pkrg0mx	247	13	bind	bind	VB
cord-321013-8pkrg0mx	247	14	to	to	IN
cord-321013-8pkrg0mx	247	15	DNA	dna	NN
cord-321013-8pkrg0mx	247	16	in	in	IN
cord-321013-8pkrg0mx	247	17	vitro	vitro	FW
cord-321013-8pkrg0mx	247	18	[	[	-LRB-
cord-321013-8pkrg0mx	247	19	55	55	CD
cord-321013-8pkrg0mx	247	20	]	]	-RRB-
cord-321013-8pkrg0mx	247	21	.	.	.
cord-321013-8pkrg0mx	248	1	Recently	recently	RB
cord-321013-8pkrg0mx	248	2	,	,	,
cord-321013-8pkrg0mx	248	3	the	the	DT
cord-321013-8pkrg0mx	248	4	N	n	CD
cord-321013-8pkrg0mx	248	5	protein	protein	NN
cord-321013-8pkrg0mx	248	6	of	of	IN
cord-321013-8pkrg0mx	248	7	hCoV	hCoV	NNP
cord-321013-8pkrg0mx	248	8	-	-	HYPH
cord-321013-8pkrg0mx	248	9	OC43	OC43	NNP
cord-321013-8pkrg0mx	248	10	was	be	VBD
cord-321013-8pkrg0mx	248	11	shown	show	VBN
cord-321013-8pkrg0mx	248	12	to	to	TO
cord-321013-8pkrg0mx	248	13	interact	interact	VB
cord-321013-8pkrg0mx	248	14	with	with	IN
cord-321013-8pkrg0mx	248	15	the	the	DT
cord-321013-8pkrg0mx	248	16	transcription	transcription	NN
cord-321013-8pkrg0mx	248	17	factor	factor	NN
cord-321013-8pkrg0mx	248	18	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	248	19	factor	factor	NN
cord-321013-8pkrg0mx	248	20	-	-	HYPH
cord-321013-8pkrg0mx	248	21	kappa	kappa	NN
cord-321013-8pkrg0mx	248	22	B	b	NN
cord-321013-8pkrg0mx	248	23	(	(	-LRB-
cord-321013-8pkrg0mx	248	24	NF	NF	NNP
cord-321013-8pkrg0mx	248	25	-	-	HYPH
cord-321013-8pkrg0mx	248	26	kappaB	kappaB	NNP
cord-321013-8pkrg0mx	248	27	)	)	-RRB-
cord-321013-8pkrg0mx	248	28	[	[	-LRB-
cord-321013-8pkrg0mx	248	29	73	73	CD
cord-321013-8pkrg0mx	248	30	]	]	-RRB-
cord-321013-8pkrg0mx	248	31	.	.	.
cord-321013-8pkrg0mx	249	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	249	2	was	be	VBD
cord-321013-8pkrg0mx	249	3	reported	report	VBN
cord-321013-8pkrg0mx	249	4	that	that	IN
cord-321013-8pkrg0mx	249	5	hCoV	hCoV	NNP
cord-321013-8pkrg0mx	249	6	-	-	HYPH
cord-321013-8pkrg0mx	249	7	OC43	OC43	NNP
cord-321013-8pkrg0mx	249	8	N	N	NNP
cord-321013-8pkrg0mx	249	9	protein	protein	NN
cord-321013-8pkrg0mx	249	10	potentiates	potentiate	VBZ
cord-321013-8pkrg0mx	249	11	NF	NF	NNP
cord-321013-8pkrg0mx	249	12	-	-	HYPH
cord-321013-8pkrg0mx	249	13	kB	kb	CD
cord-321013-8pkrg0mx	249	14	activation	activation	NN
cord-321013-8pkrg0mx	249	15	as	as	IN
cord-321013-8pkrg0mx	249	16	a	a	DT
cord-321013-8pkrg0mx	249	17	direct	direct	JJ
cord-321013-8pkrg0mx	249	18	result	result	NN
cord-321013-8pkrg0mx	249	19	of	of	IN
cord-321013-8pkrg0mx	249	20	the	the	DT
cord-321013-8pkrg0mx	249	21	ability	ability	NN
cord-321013-8pkrg0mx	249	22	of	of	IN
cord-321013-8pkrg0mx	249	23	the	the	DT
cord-321013-8pkrg0mx	249	24	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	249	25	to	to	TO
cord-321013-8pkrg0mx	249	26	bind	bind	VB
cord-321013-8pkrg0mx	249	27	microRNA	microRNA	NNP
cord-321013-8pkrg0mx	249	28	miR-9	miR-9	NNP
cord-321013-8pkrg0mx	249	29	,	,	,
cord-321013-8pkrg0mx	249	30	a	a	DT
cord-321013-8pkrg0mx	249	31	negative	negative	JJ
cord-321013-8pkrg0mx	249	32	regulator	regulator	NN
cord-321013-8pkrg0mx	249	33	of	of	IN
cord-321013-8pkrg0mx	249	34	NF	nf	NN
cord-321013-8pkrg0mx	249	35	-	-	HYPH
cord-321013-8pkrg0mx	249	36	kB.	kB.	NNP
cord-321013-8pkrg0mx	250	1	It	-PRON-	PRP
cord-321013-8pkrg0mx	250	2	was	be	VBD
cord-321013-8pkrg0mx	250	3	suggested	suggest	VBN
cord-321013-8pkrg0mx	250	4	that	that	IN
cord-321013-8pkrg0mx	250	5	this	this	DT
cord-321013-8pkrg0mx	250	6	previously	previously	RB
cord-321013-8pkrg0mx	250	7	undescribed	undescribed	JJ
cord-321013-8pkrg0mx	250	8	interaction	interaction	NN
cord-321013-8pkrg0mx	250	9	between	between	IN
cord-321013-8pkrg0mx	250	10	virus	virus	NN
cord-321013-8pkrg0mx	250	11	and	and	CC
cord-321013-8pkrg0mx	250	12	host	host	NN
cord-321013-8pkrg0mx	250	13	is	be	VBZ
cord-321013-8pkrg0mx	250	14	a	a	DT
cord-321013-8pkrg0mx	250	15	potential	potential	JJ
cord-321013-8pkrg0mx	250	16	mechanism	mechanism	NN
cord-321013-8pkrg0mx	250	17	of	of	IN
cord-321013-8pkrg0mx	250	18	immune	immune	JJ
cord-321013-8pkrg0mx	250	19	evasion	evasion	NN
cord-321013-8pkrg0mx	250	20	in	in	IN
cord-321013-8pkrg0mx	250	21	RNA	RNA	NNP
cord-321013-8pkrg0mx	250	22	viruses	virus	NNS
cord-321013-8pkrg0mx	250	23	because	because	IN
cord-321013-8pkrg0mx	250	24	NF	NF	NNP
cord-321013-8pkrg0mx	250	25	-	-	HYPH
cord-321013-8pkrg0mx	250	26	kB	kB	NNP
cord-321013-8pkrg0mx	250	27	required	require	VBD
cord-321013-8pkrg0mx	250	28	for	for	IN
cord-321013-8pkrg0mx	250	29	IF	if	NN
cord-321013-8pkrg0mx	250	30	gene	gene	NN
cord-321013-8pkrg0mx	250	31	expression	expression	NN
cord-321013-8pkrg0mx	250	32	[	[	-LRB-
cord-321013-8pkrg0mx	250	33	73	73	CD
cord-321013-8pkrg0mx	250	34	,	,	,
cord-321013-8pkrg0mx	250	35	158	158	CD
cord-321013-8pkrg0mx	250	36	]	]	-RRB-
cord-321013-8pkrg0mx	250	37	.	.	.
cord-321013-8pkrg0mx	251	1	148	148	CD
cord-321013-8pkrg0mx	251	2	]	]	-RRB-
cord-321013-8pkrg0mx	251	3	,	,	,
cord-321013-8pkrg0mx	251	4	which	which	WDT
cord-321013-8pkrg0mx	251	5	could	could	MD
cord-321013-8pkrg0mx	251	6	act	act	VB
cord-321013-8pkrg0mx	251	7	as	as	IN
cord-321013-8pkrg0mx	251	8	a	a	DT
cord-321013-8pkrg0mx	251	9	switch	switch	NN
cord-321013-8pkrg0mx	251	10	that	that	WDT
cord-321013-8pkrg0mx	251	11	redirects	redirect	VBZ
cord-321013-8pkrg0mx	251	12	viral	viral	JJ
cord-321013-8pkrg0mx	251	13	activity	activity	NN
cord-321013-8pkrg0mx	251	14	from	from	IN
cord-321013-8pkrg0mx	251	15	RNA	RNA	NNP
cord-321013-8pkrg0mx	251	16	synthesis	synthesis	NN
cord-321013-8pkrg0mx	251	17	to	to	IN
cord-321013-8pkrg0mx	251	18	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	251	19	formation	formation	NN
cord-321013-8pkrg0mx	251	20	.	.	.
cord-321013-8pkrg0mx	252	1			NFP
cord-321013-8pkrg0mx	253	1	Interaction	Interaction	NNP
cord-321013-8pkrg0mx	253	2	of	of	IN
cord-321013-8pkrg0mx	253	3	N	N	NNP
cord-321013-8pkrg0mx	253	4	protein	protein	NN
cord-321013-8pkrg0mx	253	5	CTD	CTD	NNP
cord-321013-8pkrg0mx	253	6	with	with	IN
cord-321013-8pkrg0mx	253	7	elongation	elongation	NN
cord-321013-8pkrg0mx	253	8	factor	factor	NN
cord-321013-8pkrg0mx	253	9	1α	1α	CD
cord-321013-8pkrg0mx	253	10	(	(	-LRB-
cord-321013-8pkrg0mx	253	11	EF1α	EF1α	NNP
cord-321013-8pkrg0mx	253	12	)	)	-RRB-
cord-321013-8pkrg0mx	253	13	,	,	,
cord-321013-8pkrg0mx	253	14	a	a	DT
cord-321013-8pkrg0mx	253	15	major	major	JJ
cord-321013-8pkrg0mx	253	16	translational	translational	JJ
cord-321013-8pkrg0mx	253	17	factor	factor	NN
cord-321013-8pkrg0mx	253	18	in	in	IN
cord-321013-8pkrg0mx	253	19	mammalian	mammalian	JJ
cord-321013-8pkrg0mx	253	20	cells	cell	NNS
cord-321013-8pkrg0mx	253	21	,	,	,
cord-321013-8pkrg0mx	253	22	can	can	MD
cord-321013-8pkrg0mx	253	23	suppress	suppress	VB
cord-321013-8pkrg0mx	253	24	translation	translation	NN
cord-321013-8pkrg0mx	253	25	[	[	-LRB-
cord-321013-8pkrg0mx	253	26	75	75	CD
cord-321013-8pkrg0mx	253	27	]	]	-RRB-
cord-321013-8pkrg0mx	253	28	.	.	.
cord-321013-8pkrg0mx	254	1			NFP
cord-321013-8pkrg0mx	255	1	N	N	NNP
cord-321013-8pkrg0mx	255	2	protein	protein	NN
cord-321013-8pkrg0mx	255	3	plays	play	VBZ
cord-321013-8pkrg0mx	255	4	an	an	DT
cord-321013-8pkrg0mx	255	5	important	important	JJ
cord-321013-8pkrg0mx	255	6	role	role	NN
cord-321013-8pkrg0mx	255	7	in	in	IN
cord-321013-8pkrg0mx	255	8	viral	viral	JJ
cord-321013-8pkrg0mx	255	9	pathogenesis	pathogenesis	NN
cord-321013-8pkrg0mx	255	10	.	.	.
cord-321013-8pkrg0mx	256	1	Mice	mouse	NNS
cord-321013-8pkrg0mx	256	2	infected	infect	VBN
cord-321013-8pkrg0mx	256	3	with	with	IN
cord-321013-8pkrg0mx	256	4	JMHV	JMHV	NNP
cord-321013-8pkrg0mx	256	5	protected	protect	VBN
cord-321013-8pkrg0mx	256	6	by	by	IN
cord-321013-8pkrg0mx	256	7	anti	anti	JJ
cord-321013-8pkrg0mx	256	8	-	-	JJ
cord-321013-8pkrg0mx	256	9	N	n	JJ
cord-321013-8pkrg0mx	256	10	monoclonal	monoclonal	JJ
cord-321013-8pkrg0mx	256	11	antibodies	antibody	NNS
cord-321013-8pkrg0mx	256	12	[	[	-LRB-
cord-321013-8pkrg0mx	256	13	156	156	CD
cord-321013-8pkrg0mx	256	14	]	]	-RRB-
cord-321013-8pkrg0mx	256	15	.	.	.
cord-321013-8pkrg0mx	257	1			NFP
cord-321013-8pkrg0mx	258	1	Synthesis	synthesis	NN
cord-321013-8pkrg0mx	258	2	of	of	IN
cord-321013-8pkrg0mx	258	3	type-1	type-1	NN
cord-321013-8pkrg0mx	259	1	interferon	interferon	NNP
cord-321013-8pkrg0mx	259	2	(	(	-LRB-
cord-321013-8pkrg0mx	259	3	1FN	1fn	CD
cord-321013-8pkrg0mx	259	4	)	)	-RRB-
cord-321013-8pkrg0mx	259	5	inhibited	inhibit	VBN
cord-321013-8pkrg0mx	259	6	by	by	IN
cord-321013-8pkrg0mx	259	7	SARS	SARS	NNP
cord-321013-8pkrg0mx	259	8	-	-	HYPH
cord-321013-8pkrg0mx	259	9	CoV	CoV	NNP
cord-321013-8pkrg0mx	259	10	N	N	NNP
cord-321013-8pkrg0mx	259	11	[	[	-LRB-
cord-321013-8pkrg0mx	259	12	158	158	CD
cord-321013-8pkrg0mx	259	13	]	]	-RRB-
cord-321013-8pkrg0mx	259	14	.	.	.
cord-321013-8pkrg0mx	260	1			NFP
cord-321013-8pkrg0mx	261	1	The	the	DT
cord-321013-8pkrg0mx	261	2	CTD	CTD	NNP
cord-321013-8pkrg0mx	261	3	of	of	IN
cord-321013-8pkrg0mx	261	4	N	N	NNP
cord-321013-8pkrg0mx	261	5	has	have	VBZ
cord-321013-8pkrg0mx	261	6	been	be	VBN
cord-321013-8pkrg0mx	261	7	shown	show	VBN
cord-321013-8pkrg0mx	261	8	to	to	TO
cord-321013-8pkrg0mx	261	9	be	be	VB
cord-321013-8pkrg0mx	261	10	a	a	DT
cord-321013-8pkrg0mx	261	11	critical	critical	JJ
cord-321013-8pkrg0mx	261	12	antagonist	antagonist	NN
cord-321013-8pkrg0mx	261	13	of	of	IN
cord-321013-8pkrg0mx	261	14	1FN	1fn	CD
cord-321013-8pkrg0mx	261	15	induction	induction	NN
cord-321013-8pkrg0mx	261	16	[	[	-LRB-
cord-321013-8pkrg0mx	261	17	159	159	CD
cord-321013-8pkrg0mx	261	18	]	]	-RRB-
cord-321013-8pkrg0mx	261	19	2.5	2.5	CD
cord-321013-8pkrg0mx	261	20	.	.	.
cord-321013-8pkrg0mx	262	1	Signal	signal	NN
cord-321013-8pkrg0mx	262	2	transduction	transduction	NN
cord-321013-8pkrg0mx	262	3			NFP
cord-321013-8pkrg0mx	263	1	Activation	activation	NN
cord-321013-8pkrg0mx	263	2	of	of	IN
cord-321013-8pkrg0mx	263	3	host	host	NN
cord-321013-8pkrg0mx	263	4	cell	cell	NN
cord-321013-8pkrg0mx	263	5	signal	signal	NN
cord-321013-8pkrg0mx	263	6	transduction	transduction	NN
cord-321013-8pkrg0mx	263	7	pathways	pathway	NNS
cord-321013-8pkrg0mx	263	8	and	and	CC
cord-321013-8pkrg0mx	263	9	kinases	kinase	NNS
cord-321013-8pkrg0mx	263	10	leads	lead	VBZ
cord-321013-8pkrg0mx	263	11	to	to	IN
cord-321013-8pkrg0mx	263	12	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	263	13	of	of	IN
cord-321013-8pkrg0mx	263	14	N	n	CD
cord-321013-8pkrg0mx	263	15	[	[	-LRB-
cord-321013-8pkrg0mx	263	16	160	160	CD
cord-321013-8pkrg0mx	263	17	]	]	-RRB-
cord-321013-8pkrg0mx	263	18	.	.	.
cord-321013-8pkrg0mx	264	1	NF	NF	NNP
cord-321013-8pkrg0mx	264	2	-	-	HYPH
cord-321013-8pkrg0mx	264	3	kB	kB	NNP
cord-321013-8pkrg0mx	264	4	is	be	VBZ
cord-321013-8pkrg0mx	264	5	also	also	RB
cord-321013-8pkrg0mx	264	6	involved	involve	VBN
cord-321013-8pkrg0mx	264	7	in	in	IN
cord-321013-8pkrg0mx	264	8	SARS	SARS	NNP
cord-321013-8pkrg0mx	264	9	-	-	HYPH
cord-321013-8pkrg0mx	264	10	CoV	CoV	NNP
cord-321013-8pkrg0mx	264	11	mediated	mediate	VBN
cord-321013-8pkrg0mx	264	12	activation	activation	NN
cord-321013-8pkrg0mx	264	13	of	of	IN
cord-321013-8pkrg0mx	264	14	cyclooxygenase-2	cyclooxygenase-2	NNP
cord-321013-8pkrg0mx	264	15	(	(	-LRB-
cord-321013-8pkrg0mx	264	16	COX-2	COX-2	NNP
cord-321013-8pkrg0mx	264	17	)	)	-RRB-
cord-321013-8pkrg0mx	265	1	,	,	,
cord-321013-8pkrg0mx	265	2	more	more	RBR
cord-321013-8pkrg0mx	265	3	specifically	specifically	RB
cord-321013-8pkrg0mx	265	4	,	,	,
cord-321013-8pkrg0mx	265	5	N	n	NN
cord-321013-8pkrg0mx	265	6	protein	protein	NN
cord-321013-8pkrg0mx	265	7	binds	bind	VBZ
cord-321013-8pkrg0mx	265	8	to	to	IN
cord-321013-8pkrg0mx	265	9	NF	NF	NNP
cord-321013-8pkrg0mx	265	10	-	-	HYPH
cord-321013-8pkrg0mx	265	11	kB	kB	NNP
cord-321013-8pkrg0mx	265	12	and	and	CC
cord-321013-8pkrg0mx	265	13	CCAAT	CCAAT	NNP
cord-321013-8pkrg0mx	265	14	/	/	SYM
cord-321013-8pkrg0mx	265	15	enhancer	enhancer	NN
cord-321013-8pkrg0mx	265	16	binding	bind	VBG
cord-321013-8pkrg0mx	265	17	protein	protein	NN
cord-321013-8pkrg0mx	265	18	binding	bind	VBG
cord-321013-8pkrg0mx	265	19	sites	site	NNS
cord-321013-8pkrg0mx	265	20	on	on	IN
cord-321013-8pkrg0mx	265	21	the	the	DT
cord-321013-8pkrg0mx	265	22	COX-2	cox-2	JJ
cord-321013-8pkrg0mx	265	23	gene	gene	NN
cord-321013-8pkrg0mx	265	24	promoter	promoter	NN
cord-321013-8pkrg0mx	265	25	[	[	-LRB-
cord-321013-8pkrg0mx	265	26	162	162	CD
cord-321013-8pkrg0mx	265	27	]	]	-RRB-
cord-321013-8pkrg0mx	265	28	.	.	.
cord-321013-8pkrg0mx	266	1	Activation	activation	NN
cord-321013-8pkrg0mx	266	2	of	of	IN
cord-321013-8pkrg0mx	266	3	COX-2	COX-2	NNP
cord-321013-8pkrg0mx	266	4	,	,	,
cord-321013-8pkrg0mx	266	5	a	a	DT
cord-321013-8pkrg0mx	266	6	proinflammatory	proinflammatory	JJ
cord-321013-8pkrg0mx	266	7	factor	factor	NN
cord-321013-8pkrg0mx	266	8	,	,	,
cord-321013-8pkrg0mx	266	9	by	by	IN
cord-321013-8pkrg0mx	266	10	SARS	SARS	NNP
cord-321013-8pkrg0mx	266	11	-	-	HYPH
cord-321013-8pkrg0mx	266	12	CoV	CoV	NNP
cord-321013-8pkrg0mx	267	1	N	N	NNP
cord-321013-8pkrg0mx	267	2	protein	protein	NN
cord-321013-8pkrg0mx	267	3	is	be	VBZ
cord-321013-8pkrg0mx	267	4	a	a	DT
cord-321013-8pkrg0mx	267	5	likely	likely	JJ
cord-321013-8pkrg0mx	267	6	cause	cause	NN
cord-321013-8pkrg0mx	267	7	of	of	IN
cord-321013-8pkrg0mx	267	8	lung	lung	NN
cord-321013-8pkrg0mx	267	9	inflammation	inflammation	NN
cord-321013-8pkrg0mx	267	10	in	in	IN
cord-321013-8pkrg0mx	267	11	SARS	SARS	NNP
cord-321013-8pkrg0mx	267	12	-	-	HYPH
cord-321013-8pkrg0mx	267	13	CoV	CoV	NNP
cord-321013-8pkrg0mx	267	14	infected	infect	VBN
cord-321013-8pkrg0mx	267	15	patients	patient	NNS
cord-321013-8pkrg0mx	267	16	[	[	-LRB-
cord-321013-8pkrg0mx	267	17	162	162	CD
cord-321013-8pkrg0mx	267	18	]	]	-RRB-
cord-321013-8pkrg0mx	267	19	.	.	.
cord-321013-8pkrg0mx	268	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	268	2	-	-	HYPH
cord-321013-8pkrg0mx	268	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	268	4	N	n	CD
cord-321013-8pkrg0mx	268	5	protein	protein	NN
cord-321013-8pkrg0mx	268	6	is	be	VBZ
cord-321013-8pkrg0mx	268	7	also	also	RB
cord-321013-8pkrg0mx	268	8	known	know	VBN
cord-321013-8pkrg0mx	268	9	to	to	TO
cord-321013-8pkrg0mx	268	10	activate	activate	VB
cord-321013-8pkrg0mx	268	11	the	the	DT
cord-321013-8pkrg0mx	268	12	activator	activator	NN
cord-321013-8pkrg0mx	268	13	protein	protein	NN
cord-321013-8pkrg0mx	268	14	1	1	CD
cord-321013-8pkrg0mx	268	15	(	(	-LRB-
cord-321013-8pkrg0mx	268	16	AP1	AP1	NNP
cord-321013-8pkrg0mx	268	17	)	)	-RRB-
cord-321013-8pkrg0mx	268	18	signal	signal	NN
cord-321013-8pkrg0mx	268	19	transduction	transduction	NN
cord-321013-8pkrg0mx	268	20	pathway	pathway	NN
cord-321013-8pkrg0mx	268	21	by	by	IN
cord-321013-8pkrg0mx	268	22	increasing	increase	VBG
cord-321013-8pkrg0mx	268	23	the	the	DT
cord-321013-8pkrg0mx	268	24	amount	amount	NN
cord-321013-8pkrg0mx	268	25	of	of	IN
cord-321013-8pkrg0mx	268	26	transcription	transcription	NN
cord-321013-8pkrg0mx	268	27	factors	factor	NNS
cord-321013-8pkrg0mx	268	28	binding	bind	VBG
cord-321013-8pkrg0mx	268	29	to	to	IN
cord-321013-8pkrg0mx	268	30	promoter	promoter	NN
cord-321013-8pkrg0mx	268	31	sequences	sequence	NNS
cord-321013-8pkrg0mx	268	32	of	of	IN
cord-321013-8pkrg0mx	268	33	c	c	NNP
cord-321013-8pkrg0mx	268	34	-	-	:
cord-321013-8pkrg0mx	268	35	Fos	Fos	NNP
cord-321013-8pkrg0mx	268	36	,	,	,
cord-321013-8pkrg0mx	268	37	ATF2	ATF2	NNP
cord-321013-8pkrg0mx	268	38	,	,	,
cord-321013-8pkrg0mx	268	39	CREB-1	CREB-1	NNP
cord-321013-8pkrg0mx	268	40	,	,	,
cord-321013-8pkrg0mx	268	41	and	and	CC
cord-321013-8pkrg0mx	268	42	FosB	FosB	NNP
cord-321013-8pkrg0mx	268	43	[	[	-LRB-
cord-321013-8pkrg0mx	268	44	163	163	CD
cord-321013-8pkrg0mx	268	45	]	]	-RRB-
cord-321013-8pkrg0mx	268	46	.	.	.
cord-321013-8pkrg0mx	269	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	269	2	-	-	HYPH
cord-321013-8pkrg0mx	269	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	269	4	N	n	CD
cord-321013-8pkrg0mx	269	5	protein	protein	NN
cord-321013-8pkrg0mx	269	6	induces	induce	VBZ
cord-321013-8pkrg0mx	269	7	apoptosis	apoptosis	NN
cord-321013-8pkrg0mx	269	8	of	of	IN
cord-321013-8pkrg0mx	269	9	COS-1	COS-1	NNP
cord-321013-8pkrg0mx	269	10	monkey	monkey	NN
cord-321013-8pkrg0mx	269	11	kidney	kidney	NN
cord-321013-8pkrg0mx	269	12	cells	cell	NNS
cord-321013-8pkrg0mx	269	13	in	in	IN
cord-321013-8pkrg0mx	269	14	the	the	DT
cord-321013-8pkrg0mx	269	15	absence	absence	NN
cord-321013-8pkrg0mx	269	16	of	of	IN
cord-321013-8pkrg0mx	269	17	growth	growth	NN
cord-321013-8pkrg0mx	269	18	factor	factor	NN
cord-321013-8pkrg0mx	269	19	by	by	IN
cord-321013-8pkrg0mx	269	20	down	down	RB
cord-321013-8pkrg0mx	269	21	-	-	HYPH
cord-321013-8pkrg0mx	269	22	regulating	regulate	VBG
cord-321013-8pkrg0mx	269	23	extracellular	extracellular	JJ
cord-321013-8pkrg0mx	269	24	-	-	HYPH
cord-321013-8pkrg0mx	269	25	signal	signal	NN
cord-321013-8pkrg0mx	269	26	-	-	HYPH
cord-321013-8pkrg0mx	269	27	regulated	regulate	VBN
cord-321013-8pkrg0mx	269	28	kinase	kinase	NN
cord-321013-8pkrg0mx	269	29	(	(	-LRB-
cord-321013-8pkrg0mx	269	30	ERK	ERK	NNP
cord-321013-8pkrg0mx	269	31	)	)	-RRB-
cord-321013-8pkrg0mx	269	32	and	and	CC
cord-321013-8pkrg0mx	269	33	up	up	RB
cord-321013-8pkrg0mx	269	34	-	-	HYPH
cord-321013-8pkrg0mx	269	35	regulating	regulate	VBG
cord-321013-8pkrg0mx	269	36	c	c	NN
cord-321013-8pkrg0mx	269	37	-	-	:
cord-321013-8pkrg0mx	269	38	Jun	Jun	NNP
cord-321013-8pkrg0mx	269	39	N	N	NNP
cord-321013-8pkrg0mx	269	40	-	-	HYPH
cord-321013-8pkrg0mx	269	41	terminal	terminal	NN
cord-321013-8pkrg0mx	269	42	kinase	kinase	NN
cord-321013-8pkrg0mx	269	43	(	(	-LRB-
cord-321013-8pkrg0mx	269	44	JNK	JNK	NNP
cord-321013-8pkrg0mx	269	45	)	)	-RRB-
cord-321013-8pkrg0mx	269	46	and	and	CC
cord-321013-8pkrg0mx	269	47	p38	p38	CD
cord-321013-8pkrg0mx	269	48	mitogen	mitogen	NNP
cord-321013-8pkrg0mx	269	49	-	-	HYPH
cord-321013-8pkrg0mx	269	50	activated	activate	VBN
cord-321013-8pkrg0mx	269	51	protein	protein	NN
cord-321013-8pkrg0mx	269	52	kinase	kinase	NN
cord-321013-8pkrg0mx	269	53	(	(	-LRB-
cord-321013-8pkrg0mx	269	54	MAPK	MAPK	NNP
cord-321013-8pkrg0mx	269	55	)	)	-RRB-
cord-321013-8pkrg0mx	269	56	pathways	pathway	NNS
cord-321013-8pkrg0mx	269	57	,	,	,
cord-321013-8pkrg0mx	269	58	with	with	IN
cord-321013-8pkrg0mx	269	59	activation	activation	NN
cord-321013-8pkrg0mx	269	60	of	of	IN
cord-321013-8pkrg0mx	269	61	p38	p38	CD
cord-321013-8pkrg0mx	269	62	MAPK	MAPK	NNP
cord-321013-8pkrg0mx	269	63	also	also	RB
cord-321013-8pkrg0mx	269	64	causing	cause	VBG
cord-321013-8pkrg0mx	269	65	actin	actin	JJ
cord-321013-8pkrg0mx	269	66	reorganization	reorganization	NN
cord-321013-8pkrg0mx	269	67	in	in	IN
cord-321013-8pkrg0mx	269	68	serum	serum	NN
cord-321013-8pkrg0mx	269	69	-	-	HYPH
cord-321013-8pkrg0mx	269	70	deprived	deprive	VBN
cord-321013-8pkrg0mx	269	71	cells	cell	NNS
cord-321013-8pkrg0mx	269	72	[	[	-LRB-
cord-321013-8pkrg0mx	269	73	155	155	CD
cord-321013-8pkrg0mx	269	74	]	]	-RRB-
cord-321013-8pkrg0mx	269	75	.	.	.
cord-321013-8pkrg0mx	270	1	The	the	DT
cord-321013-8pkrg0mx	270	2	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	270	3	N	n	CD
cord-321013-8pkrg0mx	270	4	protein	protein	NN
cord-321013-8pkrg0mx	270	5	is	be	VBZ
cord-321013-8pkrg0mx	270	6	abundantly	abundantly	RB
cord-321013-8pkrg0mx	270	7	produced	produce	VBN
cord-321013-8pkrg0mx	270	8	within	within	IN
cord-321013-8pkrg0mx	270	9	infected	infected	JJ
cord-321013-8pkrg0mx	270	10	cells	cell	NNS
cord-321013-8pkrg0mx	270	11	.	.	.
cord-321013-8pkrg0mx	271	1	N	N	NNP
cord-321013-8pkrg0mx	271	2	has	have	VBZ
cord-321013-8pkrg0mx	271	3	multiple	multiple	JJ
cord-321013-8pkrg0mx	271	4	functions	function	NNS
cord-321013-8pkrg0mx	271	5	,	,	,
cord-321013-8pkrg0mx	271	6	including	include	VBG
cord-321013-8pkrg0mx	271	7	binding	bind	VBG
cord-321013-8pkrg0mx	271	8	to	to	IN
cord-321013-8pkrg0mx	271	9	viral	viral	JJ
cord-321013-8pkrg0mx	271	10	RNA	RNA	NNP
cord-321013-8pkrg0mx	271	11	to	to	TO
cord-321013-8pkrg0mx	271	12	form	form	VB
cord-321013-8pkrg0mx	271	13	the	the	DT
cord-321013-8pkrg0mx	271	14	ribonucleocapsid	ribonucleocapsid	NNP
cord-321013-8pkrg0mx	271	15	and	and	CC
cord-321013-8pkrg0mx	271	16	has	have	VBZ
cord-321013-8pkrg0mx	271	17	also	also	RB
cord-321013-8pkrg0mx	271	18	been	be	VBN
cord-321013-8pkrg0mx	271	19	proposed	propose	VBN
cord-321013-8pkrg0mx	271	20	to	to	TO
cord-321013-8pkrg0mx	271	21	have	have	VB
cord-321013-8pkrg0mx	271	22	roles	role	NNS
cord-321013-8pkrg0mx	271	23	in	in	IN
cord-321013-8pkrg0mx	271	24	virus	virus	NN
cord-321013-8pkrg0mx	271	25	replication	replication	NN
cord-321013-8pkrg0mx	271	26	,	,	,
cord-321013-8pkrg0mx	271	27	transcription	transcription	NN
cord-321013-8pkrg0mx	271	28	and	and	CC
cord-321013-8pkrg0mx	271	29	translation	translation	NN
cord-321013-8pkrg0mx	271	30	.	.	.
cord-321013-8pkrg0mx	272	1	In	in	IN
cord-321013-8pkrg0mx	272	2	host	host	NN
cord-321013-8pkrg0mx	272	3	cells	cell	NNS
cord-321013-8pkrg0mx	272	4	,	,	,
cord-321013-8pkrg0mx	272	5	N	n	CD
cord-321013-8pkrg0mx	272	6	proteins	protein	NNS
cord-321013-8pkrg0mx	272	7	have	have	VBP
cord-321013-8pkrg0mx	272	8	been	be	VBN
cord-321013-8pkrg0mx	272	9	shown	show	VBN
cord-321013-8pkrg0mx	272	10	to	to	TO
cord-321013-8pkrg0mx	272	11	cause	cause	VB
cord-321013-8pkrg0mx	272	12	deregulation	deregulation	NN
cord-321013-8pkrg0mx	272	13	of	of	IN
cord-321013-8pkrg0mx	272	14	the	the	DT
cord-321013-8pkrg0mx	272	15	cell	cell	NN
cord-321013-8pkrg0mx	272	16	-	-	HYPH
cord-321013-8pkrg0mx	272	17	cycle	cycle	NN
cord-321013-8pkrg0mx	272	18	[	[	-LRB-
cord-321013-8pkrg0mx	272	19	70	70	CD
cord-321013-8pkrg0mx	272	20	,	,	,
cord-321013-8pkrg0mx	272	21	142	142	CD
cord-321013-8pkrg0mx	272	22	]	]	-RRB-
cord-321013-8pkrg0mx	272	23	,	,	,
cord-321013-8pkrg0mx	272	24	inhibit	inhibit	VB
cord-321013-8pkrg0mx	272	25	the	the	DT
cord-321013-8pkrg0mx	272	26	production	production	NN
cord-321013-8pkrg0mx	272	27	of	of	IN
cord-321013-8pkrg0mx	272	28	interferon	interferon	NN
cord-321013-8pkrg0mx	272	29	[	[	-LRB-
cord-321013-8pkrg0mx	272	30	158	158	CD
cord-321013-8pkrg0mx	272	31	]	]	-RRB-
cord-321013-8pkrg0mx	272	32	,	,	,
cord-321013-8pkrg0mx	272	33	up	up	RB
cord-321013-8pkrg0mx	272	34	-	-	TO
cord-321013-8pkrg0mx	272	35	regulate	regulate	VB
cord-321013-8pkrg0mx	272	36	the	the	DT
cord-321013-8pkrg0mx	272	37	production	production	NN
cord-321013-8pkrg0mx	272	38	of	of	IN
cord-321013-8pkrg0mx	272	39	COX2	COX2	NNP
cord-321013-8pkrg0mx	272	40	[	[	-LRB-
cord-321013-8pkrg0mx	272	41	162	162	CD
cord-321013-8pkrg0mx	272	42	]	]	-RRB-
cord-321013-8pkrg0mx	272	43	,	,	,
cord-321013-8pkrg0mx	272	44	up	up	RB
cord-321013-8pkrg0mx	272	45	-	-	TO
cord-321013-8pkrg0mx	272	46	regulate	regulate	VB
cord-321013-8pkrg0mx	272	47	the	the	DT
cord-321013-8pkrg0mx	272	48	activity	activity	NN
cord-321013-8pkrg0mx	272	49	of	of	IN
cord-321013-8pkrg0mx	272	50	AP1	ap1	NN
cord-321013-8pkrg0mx	272	51	[	[	-LRB-
cord-321013-8pkrg0mx	272	52	163	163	CD
cord-321013-8pkrg0mx	272	53	]	]	-RRB-
cord-321013-8pkrg0mx	272	54	,	,	,
cord-321013-8pkrg0mx	272	55	and	and	CC
cord-321013-8pkrg0mx	272	56	induce	induce	VB
cord-321013-8pkrg0mx	272	57	apoptosis	apoptosis	NN
cord-321013-8pkrg0mx	272	58	in	in	IN
cord-321013-8pkrg0mx	272	59	serum	serum	NN
cord-321013-8pkrg0mx	272	60	deprived	deprive	VBN
cord-321013-8pkrg0mx	272	61	cells	cell	NNS
cord-321013-8pkrg0mx	272	62	[	[	-LRB-
cord-321013-8pkrg0mx	272	63	155	155	CD
cord-321013-8pkrg0mx	272	64	]	]	-RRB-
cord-321013-8pkrg0mx	272	65	-of	-of	.
cord-321013-8pkrg0mx	273	1	all	all	DT
cord-321013-8pkrg0mx	273	2	which	which	WDT
cord-321013-8pkrg0mx	273	3	may	may	MD
cord-321013-8pkrg0mx	273	4	have	have	VB
cord-321013-8pkrg0mx	273	5	possible	possible	JJ
cord-321013-8pkrg0mx	273	6	pathological	pathological	JJ
cord-321013-8pkrg0mx	273	7	consequences	consequence	NNS
cord-321013-8pkrg0mx	273	8	[	[	-LRB-
cord-321013-8pkrg0mx	273	9	164	164	CD
cord-321013-8pkrg0mx	273	10	]	]	-RRB-
cord-321013-8pkrg0mx	273	11	.	.	.
cord-321013-8pkrg0mx	274	1	Several	several	JJ
cord-321013-8pkrg0mx	274	2	excellent	excellent	JJ
cord-321013-8pkrg0mx	274	3	reviews	review	NNS
cord-321013-8pkrg0mx	274	4	on	on	IN
cord-321013-8pkrg0mx	274	5	the	the	DT
cord-321013-8pkrg0mx	274	6	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	275	1	N	N	NNP
cord-321013-8pkrg0mx	275	2	protein	protein	NN
cord-321013-8pkrg0mx	275	3	have	have	VBP
cord-321013-8pkrg0mx	275	4	previously	previously	RB
cord-321013-8pkrg0mx	275	5	been	be	VBN
cord-321013-8pkrg0mx	275	6	published	publish	VBN
cord-321013-8pkrg0mx	275	7	[	[	-LRB-
cord-321013-8pkrg0mx	275	8	165	165	CD
cord-321013-8pkrg0mx	275	9	,	,	,
cord-321013-8pkrg0mx	275	10	166	166	CD
cord-321013-8pkrg0mx	275	11	]	]	-RRB-
cord-321013-8pkrg0mx	275	12	,	,	,
cord-321013-8pkrg0mx	275	13	including	include	VBG
cord-321013-8pkrg0mx	275	14	one	one	CD
cord-321013-8pkrg0mx	275	15	on	on	IN
cord-321013-8pkrg0mx	275	16	the	the	DT
cord-321013-8pkrg0mx	275	17	structure	structure	NN
cord-321013-8pkrg0mx	275	18	and	and	CC
cord-321013-8pkrg0mx	275	19	function	function	NN
cord-321013-8pkrg0mx	275	20	of	of	IN
cord-321013-8pkrg0mx	275	21	the	the	DT
cord-321013-8pkrg0mx	275	22	SARS	SARS	NNP
cord-321013-8pkrg0mx	275	23	-	-	HYPH
cord-321013-8pkrg0mx	275	24	CoV	CoV	NNP
cord-321013-8pkrg0mx	275	25	N	N	NNP
cord-321013-8pkrg0mx	275	26	and	and	CC
cord-321013-8pkrg0mx	275	27	its	-PRON-	PRP$
cord-321013-8pkrg0mx	275	28	interaction	interaction	NN
cord-321013-8pkrg0mx	275	29	with	with	IN
cord-321013-8pkrg0mx	275	30	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	275	31	acids	acid	NNS
cord-321013-8pkrg0mx	275	32	[	[	-LRB-
cord-321013-8pkrg0mx	275	33	19	19	CD
cord-321013-8pkrg0mx	275	34	]	]	-RRB-
cord-321013-8pkrg0mx	275	35	.	.	.
cord-321013-8pkrg0mx	276	1	Notwithstanding	notwithstanding	IN
cord-321013-8pkrg0mx	276	2	these	these	DT
cord-321013-8pkrg0mx	276	3	reviews	review	NNS
cord-321013-8pkrg0mx	276	4	,	,	,
cord-321013-8pkrg0mx	276	5	the	the	DT
cord-321013-8pkrg0mx	276	6	manner	manner	NN
cord-321013-8pkrg0mx	276	7	in	in	IN
cord-321013-8pkrg0mx	276	8	which	which	WDT
cord-321013-8pkrg0mx	276	9	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	276	10	N	n	CD
cord-321013-8pkrg0mx	276	11	proteins	protein	NNS
cord-321013-8pkrg0mx	276	12	carry	carry	VBP
cord-321013-8pkrg0mx	276	13	out	out	RP
cord-321013-8pkrg0mx	276	14	its	-PRON-	PRP$
cord-321013-8pkrg0mx	276	15	roles	role	NNS
cord-321013-8pkrg0mx	276	16	during	during	IN
cord-321013-8pkrg0mx	276	17	the	the	DT
cord-321013-8pkrg0mx	276	18	viral	viral	JJ
cord-321013-8pkrg0mx	276	19	life	life	NN
cord-321013-8pkrg0mx	276	20	cycle	cycle	NN
cord-321013-8pkrg0mx	276	21	is	be	VBZ
cord-321013-8pkrg0mx	276	22	still	still	RB
cord-321013-8pkrg0mx	276	23	not	not	RB
cord-321013-8pkrg0mx	276	24	clearly	clearly	RB
cord-321013-8pkrg0mx	276	25	understood	understand	VBN
cord-321013-8pkrg0mx	276	26	.	.	.
cord-321013-8pkrg0mx	277	1	An	an	DT
cord-321013-8pkrg0mx	277	2	important	important	JJ
cord-321013-8pkrg0mx	277	3	piece	piece	NN
cord-321013-8pkrg0mx	277	4	of	of	IN
cord-321013-8pkrg0mx	277	5	missing	miss	VBG
cord-321013-8pkrg0mx	277	6	information	information	NN
cord-321013-8pkrg0mx	277	7	lies	lie	VBZ
cord-321013-8pkrg0mx	277	8	in	in	IN
cord-321013-8pkrg0mx	277	9	the	the	DT
cord-321013-8pkrg0mx	277	10	difficulty	difficulty	NN
cord-321013-8pkrg0mx	277	11	in	in	IN
cord-321013-8pkrg0mx	277	12	resolving	resolve	VBG
cord-321013-8pkrg0mx	277	13	the	the	DT
cord-321013-8pkrg0mx	277	14	atomic	atomic	JJ
cord-321013-8pkrg0mx	277	15	structure	structure	NN
cord-321013-8pkrg0mx	277	16	of	of	IN
cord-321013-8pkrg0mx	277	17	the	the	DT
cord-321013-8pkrg0mx	277	18	RNP	RNP	NNP
cord-321013-8pkrg0mx	277	19	complex	complex	NN
cord-321013-8pkrg0mx	277	20	,	,	,
cord-321013-8pkrg0mx	277	21	which	which	WDT
cord-321013-8pkrg0mx	277	22	has	have	VBZ
cord-321013-8pkrg0mx	277	23	been	be	VBN
cord-321013-8pkrg0mx	277	24	hampered	hamper	VBN
cord-321013-8pkrg0mx	277	25	by	by	IN
cord-321013-8pkrg0mx	277	26	low	low	JJ
cord-321013-8pkrg0mx	277	27	solubility	solubility	NN
cord-321013-8pkrg0mx	277	28	of	of	IN
cord-321013-8pkrg0mx	277	29	the	the	DT
cord-321013-8pkrg0mx	277	30	RNP	RNP	NNP
cord-321013-8pkrg0mx	277	31	complex	complex	NN
cord-321013-8pkrg0mx	277	32	and	and	CC
cord-321013-8pkrg0mx	277	33	the	the	DT
cord-321013-8pkrg0mx	277	34	labile	labile	JJ
cord-321013-8pkrg0mx	277	35	nature	nature	NN
cord-321013-8pkrg0mx	277	36	of	of	IN
cord-321013-8pkrg0mx	277	37	the	the	DT
cord-321013-8pkrg0mx	277	38	full	full	JJ
cord-321013-8pkrg0mx	277	39	-	-	HYPH
cord-321013-8pkrg0mx	277	40	length	length	NN
cord-321013-8pkrg0mx	277	41	N	n	CD
cord-321013-8pkrg0mx	277	42	protein	protein	NN
cord-321013-8pkrg0mx	277	43	.	.	.
cord-321013-8pkrg0mx	278	1	In	in	IN
cord-321013-8pkrg0mx	278	2	addition	addition	NN
cord-321013-8pkrg0mx	278	3	,	,	,
cord-321013-8pkrg0mx	278	4	in	in	IN
cord-321013-8pkrg0mx	278	5	order	order	NN
cord-321013-8pkrg0mx	278	6	to	to	TO
cord-321013-8pkrg0mx	278	7	determine	determine	VB
cord-321013-8pkrg0mx	278	8	whether	whether	IN
cord-321013-8pkrg0mx	278	9	the	the	DT
cord-321013-8pkrg0mx	278	10	RNPs	rnp	NNS
cord-321013-8pkrg0mx	278	11	from	from	IN
cord-321013-8pkrg0mx	278	12	various	various	JJ
cord-321013-8pkrg0mx	278	13	coronaviruses	coronaviruse	NNS
cord-321013-8pkrg0mx	278	14	share	share	VBP
cord-321013-8pkrg0mx	278	15	a	a	DT
cord-321013-8pkrg0mx	278	16	common	common	JJ
cord-321013-8pkrg0mx	278	17	structural	structural	JJ
cord-321013-8pkrg0mx	278	18	code	code	NN
cord-321013-8pkrg0mx	278	19	,	,	,
cord-321013-8pkrg0mx	278	20	the	the	DT
cord-321013-8pkrg0mx	278	21	structure	structure	NN
cord-321013-8pkrg0mx	278	22	of	of	IN
cord-321013-8pkrg0mx	278	23	different	different	JJ
cord-321013-8pkrg0mx	278	24	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	278	25	RNPs	rnp	NNS
cord-321013-8pkrg0mx	278	26	need	need	VBP
cord-321013-8pkrg0mx	278	27	to	to	TO
cord-321013-8pkrg0mx	278	28	be	be	VB
cord-321013-8pkrg0mx	278	29	resolved	resolve	VBN
cord-321013-8pkrg0mx	278	30	[	[	-LRB-
cord-321013-8pkrg0mx	278	31	19	19	CD
cord-321013-8pkrg0mx	278	32	]	]	-RRB-
cord-321013-8pkrg0mx	278	33	.	.	.
cord-321013-8pkrg0mx	279	1	Direct	direct	JJ
cord-321013-8pkrg0mx	279	2	intraviral	intraviral	JJ
cord-321013-8pkrg0mx	279	3	protein	protein	NN
cord-321013-8pkrg0mx	279	4	-	-	HYPH
cord-321013-8pkrg0mx	279	5	N	n	CD
cord-321013-8pkrg0mx	279	6	interactions	interaction	NNS
cord-321013-8pkrg0mx	279	7	identified	identify	VBN
cord-321013-8pkrg0mx	279	8	to	to	IN
cord-321013-8pkrg0mx	279	9	date	date	NN
cord-321013-8pkrg0mx	279	10	include	include	VBP
cord-321013-8pkrg0mx	279	11	the	the	DT
cord-321013-8pkrg0mx	279	12	interaction	interaction	NN
cord-321013-8pkrg0mx	279	13	between	between	IN
cord-321013-8pkrg0mx	279	14	N	N	NNP
cord-321013-8pkrg0mx	279	15	and	and	CC
cord-321013-8pkrg0mx	279	16	M	M	NNP
cord-321013-8pkrg0mx	279	17	[	[	-LRB-
cord-321013-8pkrg0mx	279	18	61	61	CD
cord-321013-8pkrg0mx	279	19	,	,	,
cord-321013-8pkrg0mx	279	20	92	92	CD
cord-321013-8pkrg0mx	279	21	,	,	,
cord-321013-8pkrg0mx	279	22	93	93	CD
cord-321013-8pkrg0mx	279	23	]	]	-RRB-
cord-321013-8pkrg0mx	279	24	and	and	CC
cord-321013-8pkrg0mx	279	25	N	n	CD
cord-321013-8pkrg0mx	279	26	and	and	CC
cord-321013-8pkrg0mx	279	27	nsp3a	nsp3a	NNP
cord-321013-8pkrg0mx	279	28	,	,	,
cord-321013-8pkrg0mx	279	29	a	a	DT
cord-321013-8pkrg0mx	279	30	component	component	NN
cord-321013-8pkrg0mx	279	31	of	of	IN
cord-321013-8pkrg0mx	279	32	the	the	DT
cord-321013-8pkrg0mx	279	33	viral	viral	JJ
cord-321013-8pkrg0mx	279	34	replicase	replicase	NN
cord-321013-8pkrg0mx	279	35	[	[	-LRB-
cord-321013-8pkrg0mx	279	36	10	10	CD
cord-321013-8pkrg0mx	279	37	,	,	,
cord-321013-8pkrg0mx	279	38	52	52	CD
cord-321013-8pkrg0mx	279	39	]	]	-RRB-
cord-321013-8pkrg0mx	279	40	.	.	.
cord-321013-8pkrg0mx	280	1	Additionally	additionally	RB
cord-321013-8pkrg0mx	280	2	,	,	,
cord-321013-8pkrg0mx	280	3	in	in	IN
cord-321013-8pkrg0mx	280	4	MHV	mhv	NN
cord-321013-8pkrg0mx	280	5	-	-	HYPH
cord-321013-8pkrg0mx	280	6	infected	infect	VBN
cord-321013-8pkrg0mx	280	7	cells	cell	NNS
cord-321013-8pkrg0mx	280	8	,	,	,
cord-321013-8pkrg0mx	280	9	monoclonal	monoclonal	JJ
cord-321013-8pkrg0mx	280	10	anti	anti	JJ
cord-321013-8pkrg0mx	280	11	-	-	JJ
cord-321013-8pkrg0mx	280	12	N	n	JJ
cord-321013-8pkrg0mx	280	13	antibody	antibody	NN
cord-321013-8pkrg0mx	280	14	co	co	NNS
cord-321013-8pkrg0mx	280	15	-	-	NNS
cord-321013-8pkrg0mx	280	16	immunoprecipitates	immunoprecipitate	NNS
cord-321013-8pkrg0mx	280	17	both	both	CC
cord-321013-8pkrg0mx	280	18	M	M	NNP
cord-321013-8pkrg0mx	280	19	and	and	CC
cord-321013-8pkrg0mx	280	20	S	S	NNP
cord-321013-8pkrg0mx	280	21	proteins	protein	NNS
cord-321013-8pkrg0mx	280	22	;	;	:
cord-321013-8pkrg0mx	280	23	this	this	DT
cord-321013-8pkrg0mx	280	24	N	N	NNP
cord-321013-8pkrg0mx	280	25	-	-	HYPH
cord-321013-8pkrg0mx	280	26	S	s	NN
cord-321013-8pkrg0mx	280	27	interaction	interaction	NN
cord-321013-8pkrg0mx	280	28	is	be	VBZ
cord-321013-8pkrg0mx	280	29	not	not	RB
cord-321013-8pkrg0mx	280	30	a	a	DT
cord-321013-8pkrg0mx	280	31	direct	direct	JJ
cord-321013-8pkrg0mx	280	32	one	one	NN
cord-321013-8pkrg0mx	280	33	though	though	RB
cord-321013-8pkrg0mx	280	34	.	.	.
cord-321013-8pkrg0mx	281	1	Rather	rather	RB
cord-321013-8pkrg0mx	281	2	,	,	,
cord-321013-8pkrg0mx	281	3	it	-PRON-	PRP
cord-321013-8pkrg0mx	281	4	is	be	VBZ
cord-321013-8pkrg0mx	281	5	due	due	JJ
cord-321013-8pkrg0mx	281	6	to	to	IN
cord-321013-8pkrg0mx	281	7	the	the	DT
cord-321013-8pkrg0mx	281	8	interaction	interaction	NN
cord-321013-8pkrg0mx	281	9	between	between	IN
cord-321013-8pkrg0mx	281	10	S	S	NNP
cord-321013-8pkrg0mx	281	11	and	and	CC
cord-321013-8pkrg0mx	281	12	M	M	NNP
cord-321013-8pkrg0mx	281	13	protein	protein	NN
cord-321013-8pkrg0mx	281	14	[	[	-LRB-
cord-321013-8pkrg0mx	281	15	93	93	CD
cord-321013-8pkrg0mx	281	16	]	]	-RRB-
cord-321013-8pkrg0mx	281	17	,	,	,
cord-321013-8pkrg0mx	281	18	where	where	WRB
cord-321013-8pkrg0mx	281	19	the	the	DT
cord-321013-8pkrg0mx	281	20	S	S	NNP
cord-321013-8pkrg0mx	281	21	protein	protein	NN
cord-321013-8pkrg0mx	281	22	forms	form	NNS
cord-321013-8pkrg0mx	281	23	complexes	complex	NNS
cord-321013-8pkrg0mx	281	24	with	with	IN
cord-321013-8pkrg0mx	281	25	M	M	NNP
cord-321013-8pkrg0mx	281	26	protein	protein	NN
cord-321013-8pkrg0mx	281	27	in	in	IN
cord-321013-8pkrg0mx	281	28	the	the	DT
cord-321013-8pkrg0mx	281	29	endoplasmic	endoplasmic	NN
cord-321013-8pkrg0mx	281	30	reticulum	reticulum	NN
cord-321013-8pkrg0mx	281	31	(	(	-LRB-
cord-321013-8pkrg0mx	281	32	ER	ER	NNP
cord-321013-8pkrg0mx	281	33	)	)	-RRB-
cord-321013-8pkrg0mx	281	34	[	[	-LRB-
cord-321013-8pkrg0mx	281	35	167	167	CD
cord-321013-8pkrg0mx	281	36	,	,	,
cord-321013-8pkrg0mx	281	37	168	168	CD
cord-321013-8pkrg0mx	281	38	]	]	-RRB-
cord-321013-8pkrg0mx	281	39	.	.	.
cord-321013-8pkrg0mx	282	1	The	the	DT
cord-321013-8pkrg0mx	282	2	identification	identification	NN
cord-321013-8pkrg0mx	282	3	of	of	IN
cord-321013-8pkrg0mx	282	4	host	host	NN
cord-321013-8pkrg0mx	282	5	proteins	protein	NNS
cord-321013-8pkrg0mx	282	6	targeted	target	VBN
cord-321013-8pkrg0mx	282	7	by	by	IN
cord-321013-8pkrg0mx	282	8	viral	viral	JJ
cord-321013-8pkrg0mx	282	9	proteins	protein	NNS
cord-321013-8pkrg0mx	282	10	during	during	IN
cord-321013-8pkrg0mx	282	11	the	the	DT
cord-321013-8pkrg0mx	282	12	infection	infection	NN
cord-321013-8pkrg0mx	282	13	process	process	NN
cord-321013-8pkrg0mx	282	14	provides	provide	VBZ
cord-321013-8pkrg0mx	282	15	important	important	JJ
cord-321013-8pkrg0mx	282	16	insights	insight	NNS
cord-321013-8pkrg0mx	282	17	into	into	IN
cord-321013-8pkrg0mx	282	18	mechanisms	mechanism	NNS
cord-321013-8pkrg0mx	282	19	of	of	IN
cord-321013-8pkrg0mx	282	20	viral	viral	JJ
cord-321013-8pkrg0mx	282	21	protein	protein	NN
cord-321013-8pkrg0mx	282	22	function	function	NN
cord-321013-8pkrg0mx	282	23	[	[	-LRB-
cord-321013-8pkrg0mx	282	24	169	169	CD
cord-321013-8pkrg0mx	282	25	]	]	-RRB-
cord-321013-8pkrg0mx	282	26	.	.	.
cord-321013-8pkrg0mx	283	1	To	to	IN
cord-321013-8pkrg0mx	283	2	date	date	NN
cord-321013-8pkrg0mx	283	3	,	,	,
cord-321013-8pkrg0mx	283	4	the	the	DT
cord-321013-8pkrg0mx	283	5	interaction	interaction	NN
cord-321013-8pkrg0mx	283	6	of	of	IN
cord-321013-8pkrg0mx	283	7	N	n	CD
cord-321013-8pkrg0mx	283	8	with	with	IN
cord-321013-8pkrg0mx	283	9	numerous	numerous	JJ
cord-321013-8pkrg0mx	283	10	host	host	NN
cord-321013-8pkrg0mx	283	11	cell	cell	NN
cord-321013-8pkrg0mx	283	12	proteins	protein	NNS
cord-321013-8pkrg0mx	283	13	have	have	VBP
cord-321013-8pkrg0mx	283	14	been	be	VBN
cord-321013-8pkrg0mx	283	15	identified	identify	VBN
cord-321013-8pkrg0mx	283	16	,	,	,
cord-321013-8pkrg0mx	283	17	including	include	VBG
cord-321013-8pkrg0mx	283	18	hCypA	hcypa	ADD
cord-321013-8pkrg0mx	283	19	[	[	-LRB-
cord-321013-8pkrg0mx	283	20	170	170	CD
cord-321013-8pkrg0mx	283	21	]	]	-RRB-
cord-321013-8pkrg0mx	283	22	,	,	,
cord-321013-8pkrg0mx	283	23	proteasome	proteasome	VBN
cord-321013-8pkrg0mx	283	24	subunit	subunit	NN
cord-321013-8pkrg0mx	283	25	p42	p42	CD
cord-321013-8pkrg0mx	283	26	[	[	-LRB-
cord-321013-8pkrg0mx	283	27	171	171	CD
cord-321013-8pkrg0mx	283	28	]	]	-RRB-
cord-321013-8pkrg0mx	283	29	,	,	,
cord-321013-8pkrg0mx	283	30	the	the	DT
cord-321013-8pkrg0mx	283	31	B23	B23	NNP
cord-321013-8pkrg0mx	283	32	phosphoprotein	phosphoprotein	NN
cord-321013-8pkrg0mx	283	33	[	[	-LRB-
cord-321013-8pkrg0mx	283	34	172	172	CD
cord-321013-8pkrg0mx	283	35	,	,	,
cord-321013-8pkrg0mx	283	36	173	173	CD
cord-321013-8pkrg0mx	283	37	]	]	-RRB-
cord-321013-8pkrg0mx	283	38	,	,	,
cord-321013-8pkrg0mx	283	39	Smad3	Smad3	NNP
cord-321013-8pkrg0mx	283	40	[	[	-LRB-
cord-321013-8pkrg0mx	283	41	174	174	CD
cord-321013-8pkrg0mx	283	42	]	]	-RRB-
cord-321013-8pkrg0mx	283	43	,	,	,
cord-321013-8pkrg0mx	283	44	nRNP	nrnp	NN
cord-321013-8pkrg0mx	283	45	-	-	HYPH
cord-321013-8pkrg0mx	283	46	A1	a1	NN
cord-321013-8pkrg0mx	283	47	[	[	-LRB-
cord-321013-8pkrg0mx	283	48	148	148	CD
cord-321013-8pkrg0mx	283	49	]	]	-RRB-
cord-321013-8pkrg0mx	283	50	,	,	,
cord-321013-8pkrg0mx	283	51	the	the	DT
cord-321013-8pkrg0mx	283	52	chemokine	chemokine	NN
cord-321013-8pkrg0mx	283	53	CXCL16	CXCL16	NNP
cord-321013-8pkrg0mx	283	54	[	[	-LRB-
cord-321013-8pkrg0mx	283	55	175	175	CD
cord-321013-8pkrg0mx	283	56	]	]	-RRB-
cord-321013-8pkrg0mx	283	57	,	,	,
cord-321013-8pkrg0mx	283	58	translation	translation	NN
cord-321013-8pkrg0mx	283	59	elongation	elongation	NN
cord-321013-8pkrg0mx	283	60	factor-1	factor-1	IN
cord-321013-8pkrg0mx	283	61	alpha	alpha	NN
cord-321013-8pkrg0mx	283	62	[	[	-LRB-
cord-321013-8pkrg0mx	283	63	75	75	CD
cord-321013-8pkrg0mx	283	64	]	]	-RRB-
cord-321013-8pkrg0mx	283	65	,	,	,
cord-321013-8pkrg0mx	283	66	cellular	cellular	JJ
cord-321013-8pkrg0mx	283	67	pyruvate	pyruvate	NN
cord-321013-8pkrg0mx	283	68	kinase	kinase	NN
cord-321013-8pkrg0mx	283	69	protein	protein	NN
cord-321013-8pkrg0mx	283	70	[	[	-LRB-
cord-321013-8pkrg0mx	283	71	176	176	CD
cord-321013-8pkrg0mx	283	72	]	]	-RRB-
cord-321013-8pkrg0mx	283	73	,	,	,
cord-321013-8pkrg0mx	283	74	14	14	CD
cord-321013-8pkrg0mx	283	75	-	-	SYM
cord-321013-8pkrg0mx	283	76	3	3	CD
cord-321013-8pkrg0mx	283	77	-	-	SYM
cord-321013-8pkrg0mx	283	78	3	3	CD
cord-321013-8pkrg0mx	283	79	[	[	-LRB-
cord-321013-8pkrg0mx	283	80	39	39	CD
cord-321013-8pkrg0mx	283	81	]	]	-RRB-
cord-321013-8pkrg0mx	283	82	and	and	CC
cord-321013-8pkrg0mx	283	83	nucleolin	nucleolin	NNP
cord-321013-8pkrg0mx	283	84	[	[	-LRB-
cord-321013-8pkrg0mx	283	85	73	73	CD
cord-321013-8pkrg0mx	283	86	,	,	,
cord-321013-8pkrg0mx	283	87	177	177	CD
cord-321013-8pkrg0mx	283	88	]	]	-RRB-
cord-321013-8pkrg0mx	283	89	.	.	.
cord-321013-8pkrg0mx	284	1	More	more	RBR
cord-321013-8pkrg0mx	284	2	recently	recently	RB
cord-321013-8pkrg0mx	284	3	,	,	,
cord-321013-8pkrg0mx	284	4	a	a	DT
cord-321013-8pkrg0mx	284	5	study	study	NN
cord-321013-8pkrg0mx	284	6	using	use	VBG
cord-321013-8pkrg0mx	284	7	high	high	JJ
cord-321013-8pkrg0mx	284	8	-	-	HYPH
cord-321013-8pkrg0mx	284	9	throughput	throughput	NN
cord-321013-8pkrg0mx	284	10	mass	mass	NN
cord-321013-8pkrg0mx	284	11	spectrometry	spectrometry	NN
cord-321013-8pkrg0mx	284	12	identified	identify	VBD
cord-321013-8pkrg0mx	284	13	a	a	DT
cord-321013-8pkrg0mx	284	14	list	list	NN
cord-321013-8pkrg0mx	284	15	of	of	IN
cord-321013-8pkrg0mx	284	16	cellular	cellular	JJ
cord-321013-8pkrg0mx	284	17	proteins	protein	NNS
cord-321013-8pkrg0mx	284	18	that	that	WDT
cord-321013-8pkrg0mx	284	19	could	could	MD
cord-321013-8pkrg0mx	284	20	potentially	potentially	RB
cord-321013-8pkrg0mx	284	21	interact	interact	VB
cord-321013-8pkrg0mx	284	22	with	with	IN
cord-321013-8pkrg0mx	284	23	the	the	DT
cord-321013-8pkrg0mx	284	24	IBV	IBV	NNP
cord-321013-8pkrg0mx	284	25	N	N	NNP
cord-321013-8pkrg0mx	284	26	protein	protein	NN
cord-321013-8pkrg0mx	284	27	[	[	-LRB-
cord-321013-8pkrg0mx	284	28	177	177	CD
cord-321013-8pkrg0mx	284	29	]	]	-RRB-
cord-321013-8pkrg0mx	284	30	.	.	.
cord-321013-8pkrg0mx	285	1	Comparative	comparative	JJ
cord-321013-8pkrg0mx	285	2	studies	study	NNS
cord-321013-8pkrg0mx	285	3	between	between	IN
cord-321013-8pkrg0mx	285	4	various	various	JJ
cord-321013-8pkrg0mx	285	5	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	285	6	N	n	CD
cord-321013-8pkrg0mx	285	7	protein	protein	NN
cord-321013-8pkrg0mx	285	8	interactions	interaction	NNS
cord-321013-8pkrg0mx	285	9	could	could	MD
cord-321013-8pkrg0mx	285	10	provide	provide	VB
cord-321013-8pkrg0mx	285	11	valuable	valuable	JJ
cord-321013-8pkrg0mx	285	12	information	information	NN
cord-321013-8pkrg0mx	285	13	on	on	IN
cord-321013-8pkrg0mx	285	14	host	host	NN
cord-321013-8pkrg0mx	285	15	specificity	specificity	NN
cord-321013-8pkrg0mx	285	16	and	and	CC
cord-321013-8pkrg0mx	285	17	evolution	evolution	NN
cord-321013-8pkrg0mx	285	18	of	of	IN
cord-321013-8pkrg0mx	285	19	the	the	DT
cord-321013-8pkrg0mx	285	20	interactions	interaction	NNS
cord-321013-8pkrg0mx	285	21	between	between	IN
cord-321013-8pkrg0mx	285	22	N	n	NN
cord-321013-8pkrg0mx	285	23	and	and	CC
cord-321013-8pkrg0mx	285	24	host	host	NN
cord-321013-8pkrg0mx	285	25	cell	cell	NN
cord-321013-8pkrg0mx	285	26	proteins	protein	NNS
cord-321013-8pkrg0mx	285	27	.	.	.
cord-321013-8pkrg0mx	286	1	In	in	IN
cord-321013-8pkrg0mx	286	2	turn	turn	NN
cord-321013-8pkrg0mx	286	3	,	,	,
cord-321013-8pkrg0mx	286	4	this	this	DT
cord-321013-8pkrg0mx	286	5	may	may	MD
cord-321013-8pkrg0mx	286	6	offer	offer	VB
cord-321013-8pkrg0mx	286	7	insight	insight	NN
cord-321013-8pkrg0mx	286	8	into	into	IN
cord-321013-8pkrg0mx	286	9	the	the	DT
cord-321013-8pkrg0mx	286	10	development	development	NN
cord-321013-8pkrg0mx	286	11	of	of	IN
cord-321013-8pkrg0mx	286	12	novel	novel	JJ
cord-321013-8pkrg0mx	286	13	antiviral	antiviral	JJ
cord-321013-8pkrg0mx	286	14	therapeutics	therapeutic	NNS
cord-321013-8pkrg0mx	286	15	that	that	WDT
cord-321013-8pkrg0mx	286	16	target	target	VBP
cord-321013-8pkrg0mx	286	17	interactions	interaction	NNS
cord-321013-8pkrg0mx	286	18	between	between	IN
cord-321013-8pkrg0mx	286	19	host	host	NN
cord-321013-8pkrg0mx	286	20	cell	cell	NN
cord-321013-8pkrg0mx	286	21	proteins	protein	NNS
cord-321013-8pkrg0mx	286	22	and	and	CC
cord-321013-8pkrg0mx	286	23	the	the	DT
cord-321013-8pkrg0mx	286	24	N	N	NNP
cord-321013-8pkrg0mx	286	25	protein	protein	NN
cord-321013-8pkrg0mx	286	26	[	[	-LRB-
cord-321013-8pkrg0mx	286	27	177	177	CD
cord-321013-8pkrg0mx	286	28	,	,	,
cord-321013-8pkrg0mx	286	29	178	178	CD
cord-321013-8pkrg0mx	286	30	]	]	-RRB-
cord-321013-8pkrg0mx	286	31	.	.	.
cord-321013-8pkrg0mx	287	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	287	2	-	-	HYPH
cord-321013-8pkrg0mx	287	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	287	4	N	n	CD
cord-321013-8pkrg0mx	287	5	protein	protein	NN
cord-321013-8pkrg0mx	287	6	is	be	VBZ
cord-321013-8pkrg0mx	287	7	extremely	extremely	RB
cord-321013-8pkrg0mx	287	8	antigenic	antigenic	JJ
cord-321013-8pkrg0mx	287	9	.	.	.
cord-321013-8pkrg0mx	288	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	288	2	-	-	HYPH
cord-321013-8pkrg0mx	288	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	288	4	infection	infection	NN
cord-321013-8pkrg0mx	288	5	causes	cause	VBZ
cord-321013-8pkrg0mx	288	6	a	a	DT
cord-321013-8pkrg0mx	288	7	highly	highly	RB
cord-321013-8pkrg0mx	288	8	restricted	restrict	VBN
cord-321013-8pkrg0mx	288	9	,	,	,
cord-321013-8pkrg0mx	288	10	immunoglobulin	immunoglobulin	NN
cord-321013-8pkrg0mx	288	11	G	g	NN
cord-321013-8pkrg0mx	288	12	-	-	HYPH
cord-321013-8pkrg0mx	288	13	dominated	dominate	VBN
cord-321013-8pkrg0mx	288	14	antibody	antibody	NN
cord-321013-8pkrg0mx	288	15	response	response	NN
cord-321013-8pkrg0mx	288	16	that	that	WDT
cord-321013-8pkrg0mx	288	17	is	be	VBZ
cord-321013-8pkrg0mx	288	18	directed	direct	VBN
cord-321013-8pkrg0mx	288	19	most	most	RBS
cord-321013-8pkrg0mx	288	20	frequently	frequently	RB
cord-321013-8pkrg0mx	288	21	and	and	CC
cord-321013-8pkrg0mx	288	22	predominantly	predominantly	RB
cord-321013-8pkrg0mx	288	23	at	at	IN
cord-321013-8pkrg0mx	288	24	the	the	DT
cord-321013-8pkrg0mx	288	25	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	288	26	[	[	-LRB-
cord-321013-8pkrg0mx	288	27	179	179	CD
cord-321013-8pkrg0mx	288	28	]	]	-RRB-
cord-321013-8pkrg0mx	288	29	.	.	.
cord-321013-8pkrg0mx	289	1	DNA	dna	NN
cord-321013-8pkrg0mx	289	2	vaccines	vaccine	NNS
cord-321013-8pkrg0mx	289	3	encoding	encode	VBG
cord-321013-8pkrg0mx	290	1	SARS	SARS	NNP
cord-321013-8pkrg0mx	290	2	-	-	HYPH
cord-321013-8pkrg0mx	290	3	CoV	CoV	NNP
cord-321013-8pkrg0mx	290	4	N	n	CD
cord-321013-8pkrg0mx	290	5	protein	protein	NN
cord-321013-8pkrg0mx	290	6	generate	generate	VBP
cord-321013-8pkrg0mx	290	7	a	a	DT
cord-321013-8pkrg0mx	290	8	strong	strong	JJ
cord-321013-8pkrg0mx	290	9	N	n	CD
cord-321013-8pkrg0mx	290	10	-	-	HYPH
cord-321013-8pkrg0mx	290	11	specific	specific	JJ
cord-321013-8pkrg0mx	290	12	humoral	humoral	JJ
cord-321013-8pkrg0mx	290	13	and	and	CC
cord-321013-8pkrg0mx	290	14	T	t	NN
cord-321013-8pkrg0mx	290	15	-	-	HYPH
cord-321013-8pkrg0mx	290	16	cell	cell	NN
cord-321013-8pkrg0mx	290	17	-	-	HYPH
cord-321013-8pkrg0mx	290	18	mediated	mediate	VBN
cord-321013-8pkrg0mx	290	19	response	response	NN
cord-321013-8pkrg0mx	290	20	and	and	CC
cord-321013-8pkrg0mx	290	21	significantly	significantly	RB
cord-321013-8pkrg0mx	290	22	reduce	reduce	VB
cord-321013-8pkrg0mx	290	23	the	the	DT
cord-321013-8pkrg0mx	290	24	viral	viral	JJ
cord-321013-8pkrg0mx	290	25	titre	titre	NN
cord-321013-8pkrg0mx	290	26	of	of	IN
cord-321013-8pkrg0mx	290	27	challenging	challenging	JJ
cord-321013-8pkrg0mx	290	28	vaccinia	vaccinia	NN
cord-321013-8pkrg0mx	290	29	virus	virus	NN
cord-321013-8pkrg0mx	290	30	in	in	IN
cord-321013-8pkrg0mx	290	31	C57BL/6-vaccinated	C57BL/6-vaccinated	NNP
cord-321013-8pkrg0mx	290	32	mice	mouse	NNS
cord-321013-8pkrg0mx	290	33	[	[	-LRB-
cord-321013-8pkrg0mx	290	34	180	180	CD
cord-321013-8pkrg0mx	290	35	]	]	-RRB-
cord-321013-8pkrg0mx	290	36	.	.	.
cord-321013-8pkrg0mx	291	1	Importantly	importantly	RB
cord-321013-8pkrg0mx	291	2	though	though	RB
cord-321013-8pkrg0mx	291	3	,	,	,
cord-321013-8pkrg0mx	291	4	another	another	DT
cord-321013-8pkrg0mx	291	5	study	study	NN
cord-321013-8pkrg0mx	291	6	suggests	suggest	VBZ
cord-321013-8pkrg0mx	291	7	that	that	IN
cord-321013-8pkrg0mx	291	8	N	n	NN
cord-321013-8pkrg0mx	291	9	does	do	VBZ
cord-321013-8pkrg0mx	291	10	not	not	RB
cord-321013-8pkrg0mx	291	11	induce	induce	VB
cord-321013-8pkrg0mx	291	12	virus	virus	NN
cord-321013-8pkrg0mx	291	13	neutralizing	neutralize	VBG
cord-321013-8pkrg0mx	291	14	antibody	antibody	NN
cord-321013-8pkrg0mx	291	15	and	and	CC
cord-321013-8pkrg0mx	291	16	as	as	IN
cord-321013-8pkrg0mx	291	17	a	a	DT
cord-321013-8pkrg0mx	291	18	result	result	NN
cord-321013-8pkrg0mx	291	19	,	,	,
cord-321013-8pkrg0mx	291	20	provides	provide	VBZ
cord-321013-8pkrg0mx	291	21	no	no	DT
cord-321013-8pkrg0mx	291	22	protection	protection	NN
cord-321013-8pkrg0mx	291	23	to	to	IN
cord-321013-8pkrg0mx	291	24	infection	infection	NN
cord-321013-8pkrg0mx	291	25	in	in	IN
cord-321013-8pkrg0mx	291	26	hamsters	hamster	NNS
cord-321013-8pkrg0mx	291	27	[	[	-LRB-
cord-321013-8pkrg0mx	291	28	181	181	CD
cord-321013-8pkrg0mx	291	29	]	]	-RRB-
cord-321013-8pkrg0mx	291	30	.	.	.
cord-321013-8pkrg0mx	292	1	In	in	IN
cord-321013-8pkrg0mx	292	2	the	the	DT
cord-321013-8pkrg0mx	292	3	diagnosis	diagnosis	NN
cord-321013-8pkrg0mx	292	4	/	/	SYM
cord-321013-8pkrg0mx	292	5	screening	screen	VBG
cord-321013-8pkrg0mx	292	6	hCoV	hCoV	NNP
cord-321013-8pkrg0mx	292	7	-	-	HYPH
cord-321013-8pkrg0mx	292	8	OC43	OC43	NNP
cord-321013-8pkrg0mx	292	9	,	,	,
cord-321013-8pkrg0mx	292	10	rabbit	rabbit	NN
cord-321013-8pkrg0mx	292	11	poloyclonal	poloyclonal	FW
cord-321013-8pkrg0mx	292	12	antibodies	antibody	NNS
cord-321013-8pkrg0mx	292	13	demonstrated	demonstrate	VBD
cord-321013-8pkrg0mx	292	14	greater	great	JJR
cord-321013-8pkrg0mx	292	15	immunoreactivity	immunoreactivity	NN
cord-321013-8pkrg0mx	292	16	to	to	IN
cord-321013-8pkrg0mx	292	17	the	the	DT
cord-321013-8pkrg0mx	292	18	central	central	JJ
cord-321013-8pkrg0mx	292	19	(	(	-LRB-
cord-321013-8pkrg0mx	292	20	LKR	LKR	NNP
cord-321013-8pkrg0mx	292	21	)	)	-RRB-
cord-321013-8pkrg0mx	292	22	region	region	NN
cord-321013-8pkrg0mx	292	23	and	and	CC
cord-321013-8pkrg0mx	292	24	CTD	CTD	NNP
cord-321013-8pkrg0mx	292	25	than	than	IN
cord-321013-8pkrg0mx	292	26	the	the	DT
cord-321013-8pkrg0mx	292	27	NTD	NTD	NNP
cord-321013-8pkrg0mx	292	28	of	of	IN
cord-321013-8pkrg0mx	292	29	N	n	CD
cord-321013-8pkrg0mx	292	30	protein	protein	NN
cord-321013-8pkrg0mx	292	31	in	in	IN
cord-321013-8pkrg0mx	292	32	serum	serum	NN
cord-321013-8pkrg0mx	292	33	samples	sample	NNS
cord-321013-8pkrg0mx	292	34	,	,	,
cord-321013-8pkrg0mx	292	35	highlighting	highlight	VBG
cord-321013-8pkrg0mx	292	36	that	that	IN
cord-321013-8pkrg0mx	292	37	LKR	LKR	NNP
cord-321013-8pkrg0mx	292	38	region	region	NN
cord-321013-8pkrg0mx	292	39	is	be	VBZ
cord-321013-8pkrg0mx	292	40	a	a	DT
cord-321013-8pkrg0mx	292	41	strong	strong	JJ
cord-321013-8pkrg0mx	292	42	candidate	candidate	NN
cord-321013-8pkrg0mx	292	43	for	for	IN
cord-321013-8pkrg0mx	292	44	use	use	NN
cord-321013-8pkrg0mx	292	45	in	in	IN
cord-321013-8pkrg0mx	292	46	the	the	DT
cord-321013-8pkrg0mx	292	47	design	design	NN
cord-321013-8pkrg0mx	292	48	of	of	IN
cord-321013-8pkrg0mx	292	49	diagnostic	diagnostic	JJ
cord-321013-8pkrg0mx	292	50	tools	tool	NNS
cord-321013-8pkrg0mx	292	51	[	[	-LRB-
cord-321013-8pkrg0mx	292	52	182	182	CD
cord-321013-8pkrg0mx	292	53	]	]	-RRB-
cord-321013-8pkrg0mx	292	54	.	.	.
cord-321013-8pkrg0mx	293	1	Understanding	understand	VBG
cord-321013-8pkrg0mx	293	2	the	the	DT
cord-321013-8pkrg0mx	293	3	role	role	NN
cord-321013-8pkrg0mx	293	4	of	of	IN
cord-321013-8pkrg0mx	293	5	N	n	CD
cord-321013-8pkrg0mx	293	6	in	in	IN
cord-321013-8pkrg0mx	293	7	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	293	8	infection	infection	NN
cord-321013-8pkrg0mx	293	9	could	could	MD
cord-321013-8pkrg0mx	293	10	lead	lead	VB
cord-321013-8pkrg0mx	293	11	to	to	IN
cord-321013-8pkrg0mx	293	12	the	the	DT
cord-321013-8pkrg0mx	293	13	development	development	NN
cord-321013-8pkrg0mx	293	14	of	of	IN
cord-321013-8pkrg0mx	293	15	novel	novel	JJ
cord-321013-8pkrg0mx	293	16	therapeutics	therapeutic	NNS
cord-321013-8pkrg0mx	293	17	that	that	WDT
cord-321013-8pkrg0mx	293	18	could	could	MD
cord-321013-8pkrg0mx	293	19	potentially	potentially	RB
cord-321013-8pkrg0mx	293	20	be	be	VB
cord-321013-8pkrg0mx	293	21	used	use	VBN
cord-321013-8pkrg0mx	293	22	to	to	TO
cord-321013-8pkrg0mx	293	23	combat	combat	VB
cord-321013-8pkrg0mx	293	24	the	the	DT
cord-321013-8pkrg0mx	293	25	threat	threat	NN
cord-321013-8pkrg0mx	293	26	posed	pose	VBN
cord-321013-8pkrg0mx	293	27	by	by	IN
cord-321013-8pkrg0mx	293	28	the	the	DT
cord-321013-8pkrg0mx	293	29	emerging	emerge	VBG
cord-321013-8pkrg0mx	293	30	lethal	lethal	JJ
cord-321013-8pkrg0mx	293	31	human	human	JJ
cord-321013-8pkrg0mx	293	32	coronaviruses	coronaviruse	NNS
cord-321013-8pkrg0mx	293	33	identified	identify	VBN
cord-321013-8pkrg0mx	293	34	in	in	IN
cord-321013-8pkrg0mx	293	35	recent	recent	JJ
cord-321013-8pkrg0mx	293	36	times	time	NNS
cord-321013-8pkrg0mx	293	37	.	.	.
cord-321013-8pkrg0mx	293	38	 	 	_SP
cord-321013-8pkrg0mx	294	1	A	a	DT
cord-321013-8pkrg0mx	294	2	decade	decade	NN
cord-321013-8pkrg0mx	294	3	after	after	IN
cord-321013-8pkrg0mx	294	4	SARS	SARS	NNP
cord-321013-8pkrg0mx	294	5	:	:	:
cord-321013-8pkrg0mx	294	6	Strategies	strategy	NNS
cord-321013-8pkrg0mx	294	7	for	for	IN
cord-321013-8pkrg0mx	294	8	controlling	control	VBG
cord-321013-8pkrg0mx	294	9	emerging	emerge	VBG
cord-321013-8pkrg0mx	294	10	coronaviruses	coronaviruse	NNS
cord-321013-8pkrg0mx	295	1	Human	human	JJ
cord-321013-8pkrg0mx	295	2	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	296	1	NL63	NL63	NNP
cord-321013-8pkrg0mx	296	2	:	:	:
cord-321013-8pkrg0mx	297	1	A	a	DT
cord-321013-8pkrg0mx	297	2	clinically	clinically	RB
cord-321013-8pkrg0mx	297	3	important	important	JJ
cord-321013-8pkrg0mx	297	4	virus	virus	NN
cord-321013-8pkrg0mx	297	5	?	?	.
cord-321013-8pkrg0mx	298	1	Future	Future	NNP
cord-321013-8pkrg0mx	298	2	Microbiol	Microbiol	NNP
cord-321013-8pkrg0mx	299	1	The	the	DT
cord-321013-8pkrg0mx	299	2	International	International	NNP
cord-321013-8pkrg0mx	299	3	Committee	Committee	NNP
cord-321013-8pkrg0mx	299	4	for	for	IN
cord-321013-8pkrg0mx	299	5	Taxonomy	Taxonomy	NNP
cord-321013-8pkrg0mx	299	6	of	of	IN
cord-321013-8pkrg0mx	299	7	Viruses	Viruses	NNPS
cord-321013-8pkrg0mx	299	8	(	(	-LRB-
cord-321013-8pkrg0mx	299	9	ICTV	ICTV	NNP
cord-321013-8pkrg0mx	299	10	)	)	-RRB-
cord-321013-8pkrg0mx	300	1	The	the	DT
cord-321013-8pkrg0mx	300	2	molecular	molecular	JJ
cord-321013-8pkrg0mx	300	3	biology	biology	NN
cord-321013-8pkrg0mx	300	4	of	of	IN
cord-321013-8pkrg0mx	300	5	coronaviruses	coronaviruse	NNS
cord-321013-8pkrg0mx	301	1	The	the	DT
cord-321013-8pkrg0mx	301	2	novel	novel	JJ
cord-321013-8pkrg0mx	301	3	human	human	NN
cord-321013-8pkrg0mx	301	4	coronaviruses	coronaviruse	NNS
cord-321013-8pkrg0mx	302	1	NL63	NL63	NNP
cord-321013-8pkrg0mx	302	2	and	and	CC
cord-321013-8pkrg0mx	302	3	HKU1	HKU1	NNP
cord-321013-8pkrg0mx	302	4	Proteolytic	Proteolytic	NNP
cord-321013-8pkrg0mx	302	5	processing	processing	NN
cord-321013-8pkrg0mx	302	6	of	of	IN
cord-321013-8pkrg0mx	302	7	polyproteins	polyproteins	NNP
cord-321013-8pkrg0mx	302	8	1a	1a	NNP
cord-321013-8pkrg0mx	302	9	and	and	CC
cord-321013-8pkrg0mx	302	10	1ab	1ab	CD
cord-321013-8pkrg0mx	302	11	between	between	IN
cord-321013-8pkrg0mx	302	12	non	non	JJ
cord-321013-8pkrg0mx	302	13	-	-	JJ
cord-321013-8pkrg0mx	302	14	structural	structural	JJ
cord-321013-8pkrg0mx	302	15	proteins	protein	NNS
cord-321013-8pkrg0mx	302	16	10	10	CD
cord-321013-8pkrg0mx	302	17	and	and	CC
cord-321013-8pkrg0mx	302	18	11/12	11/12	CD
cord-321013-8pkrg0mx	302	19	of	of	IN
cord-321013-8pkrg0mx	302	20	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	302	21	infectious	infectious	JJ
cord-321013-8pkrg0mx	302	22	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	302	23	virus	virus	NN
cord-321013-8pkrg0mx	302	24	is	be	VBZ
cord-321013-8pkrg0mx	302	25	dispensable	dispensable	JJ
cord-321013-8pkrg0mx	302	26	for	for	IN
cord-321013-8pkrg0mx	302	27	viral	viral	JJ
cord-321013-8pkrg0mx	302	28	replication	replication	NN
cord-321013-8pkrg0mx	302	29	in	in	IN
cord-321013-8pkrg0mx	302	30	cultured	cultured	JJ
cord-321013-8pkrg0mx	302	31	cells	cell	NNS
cord-321013-8pkrg0mx	303	1	An	an	DT
cord-321013-8pkrg0mx	303	2	efficient	efficient	JJ
cord-321013-8pkrg0mx	303	3	ribosomal	ribosomal	JJ
cord-321013-8pkrg0mx	303	4	frame	frame	NN
cord-321013-8pkrg0mx	303	5	-	-	HYPH
cord-321013-8pkrg0mx	303	6	shifting	shift	VBG
cord-321013-8pkrg0mx	303	7	signal	signal	NN
cord-321013-8pkrg0mx	303	8	in	in	IN
cord-321013-8pkrg0mx	303	9	the	the	DT
cord-321013-8pkrg0mx	303	10	polymerase	polymerase	NN
cord-321013-8pkrg0mx	303	11	-	-	HYPH
cord-321013-8pkrg0mx	303	12	encoding	encode	VBG
cord-321013-8pkrg0mx	303	13	region	region	NN
cord-321013-8pkrg0mx	303	14	of	of	IN
cord-321013-8pkrg0mx	303	15	the	the	DT
cord-321013-8pkrg0mx	303	16	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	303	17	IBV	IBV	NNP
cord-321013-8pkrg0mx	303	18	Ultrastructure	Ultrastructure	NNP
cord-321013-8pkrg0mx	303	19	and	and	CC
cord-321013-8pkrg0mx	303	20	origin	origin	NN
cord-321013-8pkrg0mx	303	21	of	of	IN
cord-321013-8pkrg0mx	303	22	membrane	membrane	NN
cord-321013-8pkrg0mx	303	23	vesicles	vesicle	NNS
cord-321013-8pkrg0mx	303	24	associated	associate	VBN
cord-321013-8pkrg0mx	303	25	with	with	IN
cord-321013-8pkrg0mx	303	26	the	the	DT
cord-321013-8pkrg0mx	303	27	severe	severe	JJ
cord-321013-8pkrg0mx	303	28	acute	acute	JJ
cord-321013-8pkrg0mx	303	29	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	303	30	syndrome	syndrome	NN
cord-321013-8pkrg0mx	303	31	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	303	32	replication	replication	NN
cord-321013-8pkrg0mx	303	33	complex	complex	JJ
cord-321013-8pkrg0mx	303	34	Coronaviruses	Coronaviruses	NNP
cord-321013-8pkrg0mx	303	35	post	post	NN
cord-321013-8pkrg0mx	303	36	-	-	JJ
cord-321013-8pkrg0mx	303	37	SARS	SARS	NNP
cord-321013-8pkrg0mx	303	38	:	:	:
cord-321013-8pkrg0mx	303	39	Update	update	VB
cord-321013-8pkrg0mx	303	40	on	on	IN
cord-321013-8pkrg0mx	303	41	replication	replication	NN
cord-321013-8pkrg0mx	303	42	and	and	CC
cord-321013-8pkrg0mx	303	43	pathogenesis	pathogenesis	NN
cord-321013-8pkrg0mx	304	1	Unique	unique	JJ
cord-321013-8pkrg0mx	304	2	and	and	CC
cord-321013-8pkrg0mx	304	3	conserved	conserve	VBN
cord-321013-8pkrg0mx	304	4	features	feature	NNS
cord-321013-8pkrg0mx	304	5	of	of	IN
cord-321013-8pkrg0mx	304	6	genome	genome	NN
cord-321013-8pkrg0mx	304	7	and	and	CC
cord-321013-8pkrg0mx	304	8	proteome	proteome	NN
cord-321013-8pkrg0mx	304	9	of	of	IN
cord-321013-8pkrg0mx	304	10	SARS	SARS	NNP
cord-321013-8pkrg0mx	304	11	-	-	HYPH
cord-321013-8pkrg0mx	304	12	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	304	13	,	,	,
cord-321013-8pkrg0mx	304	14	an	an	DT
cord-321013-8pkrg0mx	304	15	early	early	JJ
cord-321013-8pkrg0mx	304	16	split	split	NN
cord-321013-8pkrg0mx	304	17	-	-	HYPH
cord-321013-8pkrg0mx	304	18	off	off	NN
cord-321013-8pkrg0mx	304	19	from	from	IN
cord-321013-8pkrg0mx	304	20	the	the	DT
cord-321013-8pkrg0mx	304	21	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	304	22	group	group	NN
cord-321013-8pkrg0mx	304	23	2	2	CD
cord-321013-8pkrg0mx	304	24	lineage	lineage	NN
cord-321013-8pkrg0mx	304	25	Mechanisms	mechanism	NNS
cord-321013-8pkrg0mx	304	26	and	and	CC
cord-321013-8pkrg0mx	304	27	enzymes	enzyme	NNS
cord-321013-8pkrg0mx	304	28	involved	involve	VBN
cord-321013-8pkrg0mx	304	29	in	in	IN
cord-321013-8pkrg0mx	304	30	SARS	SARS	NNP
cord-321013-8pkrg0mx	304	31	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	304	32	genome	genome	NN
cord-321013-8pkrg0mx	304	33	expression	expression	NN
cord-321013-8pkrg0mx	305	1	The	the	DT
cord-321013-8pkrg0mx	305	2	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	305	3	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	305	4	protein	protein	NN
cord-321013-8pkrg0mx	306	1	The	the	DT
cord-321013-8pkrg0mx	306	2	molecular	molecular	JJ
cord-321013-8pkrg0mx	306	3	biology	biology	NN
cord-321013-8pkrg0mx	306	4	of	of	IN
cord-321013-8pkrg0mx	306	5	coronaviruses	coronaviruse	NNS
cord-321013-8pkrg0mx	307	1	Localization	localization	NN
cord-321013-8pkrg0mx	307	2	of	of	IN
cord-321013-8pkrg0mx	307	3	an	an	DT
cord-321013-8pkrg0mx	307	4	RNA	rna	NN
cord-321013-8pkrg0mx	307	5	-	-	HYPH
cord-321013-8pkrg0mx	307	6	binding	bind	VBG
cord-321013-8pkrg0mx	307	7	domain	domain	NN
cord-321013-8pkrg0mx	307	8	in	in	IN
cord-321013-8pkrg0mx	307	9	the	the	DT
cord-321013-8pkrg0mx	307	10	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	307	11	protein	protein	NN
cord-321013-8pkrg0mx	307	12	of	of	IN
cord-321013-8pkrg0mx	307	13	the	the	DT
cord-321013-8pkrg0mx	307	14	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	307	15	mouse	mouse	NN
cord-321013-8pkrg0mx	307	16	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	307	17	virus	virus	NN
cord-321013-8pkrg0mx	307	18	Sequence	sequence	NN
cord-321013-8pkrg0mx	307	19	comparison	comparison	NN
cord-321013-8pkrg0mx	307	20	of	of	IN
cord-321013-8pkrg0mx	307	21	the	the	DT
cord-321013-8pkrg0mx	307	22	N	n	CD
cord-321013-8pkrg0mx	307	23	genes	gene	NNS
cord-321013-8pkrg0mx	307	24	of	of	IN
cord-321013-8pkrg0mx	307	25	five	five	CD
cord-321013-8pkrg0mx	307	26	strains	strain	NNS
cord-321013-8pkrg0mx	307	27	of	of	IN
cord-321013-8pkrg0mx	307	28	the	the	DT
cord-321013-8pkrg0mx	307	29	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	307	30	mouse	mouse	NN
cord-321013-8pkrg0mx	307	31	hepatitis	hepatitis	NNP
cord-321013-8pkrg0mx	307	32	virus	virus	NN
cord-321013-8pkrg0mx	307	33	suggests	suggest	VBZ
cord-321013-8pkrg0mx	307	34	a	a	DT
cord-321013-8pkrg0mx	307	35	three	three	CD
cord-321013-8pkrg0mx	307	36	domain	domain	NN
cord-321013-8pkrg0mx	307	37	structure	structure	NN
cord-321013-8pkrg0mx	307	38	for	for	IN
cord-321013-8pkrg0mx	307	39	the	the	DT
cord-321013-8pkrg0mx	307	40	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	307	41	protein	protein	NNP
cord-321013-8pkrg0mx	307	42	Structure	Structure	NNP
cord-321013-8pkrg0mx	307	43	of	of	IN
cord-321013-8pkrg0mx	307	44	the	the	DT
cord-321013-8pkrg0mx	307	45	N	n	CD
cord-321013-8pkrg0mx	307	46	-	-	HYPH
cord-321013-8pkrg0mx	307	47	terminal	terminal	NN
cord-321013-8pkrg0mx	307	48	RNA	RNA	NNP
cord-321013-8pkrg0mx	307	49	-	-	HYPH
cord-321013-8pkrg0mx	307	50	binding	bind	VBG
cord-321013-8pkrg0mx	307	51	domain	domain	NN
cord-321013-8pkrg0mx	307	52	of	of	IN
cord-321013-8pkrg0mx	307	53	the	the	DT
cord-321013-8pkrg0mx	307	54	SARS	SARS	NNP
cord-321013-8pkrg0mx	307	55	CoV	CoV	NNP
cord-321013-8pkrg0mx	307	56	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	307	57	protein	protein	NNP
cord-321013-8pkrg0mx	308	1	The	the	DT
cord-321013-8pkrg0mx	308	2	dimer	dimer	NN
cord-321013-8pkrg0mx	308	3	interface	interface	NN
cord-321013-8pkrg0mx	308	4	of	of	IN
cord-321013-8pkrg0mx	308	5	the	the	DT
cord-321013-8pkrg0mx	308	6	SARS	SARS	NNP
cord-321013-8pkrg0mx	308	7	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	308	8	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	308	9	protein	protein	NN
cord-321013-8pkrg0mx	308	10	adapts	adapt	VBZ
cord-321013-8pkrg0mx	308	11	a	a	DT
cord-321013-8pkrg0mx	308	12	porcine	porcine	JJ
cord-321013-8pkrg0mx	308	13	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	308	14	and	and	CC
cord-321013-8pkrg0mx	308	15	reproductive	reproductive	JJ
cord-321013-8pkrg0mx	308	16	syndrome	syndrome	NN
cord-321013-8pkrg0mx	308	17	virus	virus	NN
cord-321013-8pkrg0mx	308	18	-	-	:
cord-321013-8pkrg0mx	308	19	like	like	JJ
cord-321013-8pkrg0mx	308	20	structure	structure	NN
cord-321013-8pkrg0mx	308	21	Functional	functional	JJ
cord-321013-8pkrg0mx	308	22	transcriptional	transcriptional	JJ
cord-321013-8pkrg0mx	308	23	regulatory	regulatory	JJ
cord-321013-8pkrg0mx	308	24	sequence	sequence	NN
cord-321013-8pkrg0mx	308	25	(	(	-LRB-
cord-321013-8pkrg0mx	308	26	TRS	TRS	NNP
cord-321013-8pkrg0mx	308	27	)	)	-RRB-
cord-321013-8pkrg0mx	308	28	RNA	RNA	NNP
cord-321013-8pkrg0mx	308	29	binding	binding	NN
cord-321013-8pkrg0mx	308	30	and	and	CC
cord-321013-8pkrg0mx	308	31	helix	helix	NN
cord-321013-8pkrg0mx	308	32	destabilizing	destabilizing	JJ
cord-321013-8pkrg0mx	308	33	determinants	determinant	NNS
cord-321013-8pkrg0mx	308	34	of	of	IN
cord-321013-8pkrg0mx	308	35	murine	murine	JJ
cord-321013-8pkrg0mx	308	36	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	308	37	virus	virus	NN
cord-321013-8pkrg0mx	308	38	(	(	-LRB-
cord-321013-8pkrg0mx	308	39	MHV	MHV	NNP
cord-321013-8pkrg0mx	308	40	)	)	-RRB-
cord-321013-8pkrg0mx	308	41	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	308	42	(	(	-LRB-
cord-321013-8pkrg0mx	308	43	N	N	NNP
cord-321013-8pkrg0mx	308	44	)	)	-RRB-
cord-321013-8pkrg0mx	308	45	protein	protein	NN
cord-321013-8pkrg0mx	309	1	The	the	DT
cord-321013-8pkrg0mx	309	2	SARS	SARS	NNP
cord-321013-8pkrg0mx	309	3	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	309	4	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	309	5	protein	protein	NN
cord-321013-8pkrg0mx	309	6	-	-	HYPH
cord-321013-8pkrg0mx	309	7	Forms	form	NNS
cord-321013-8pkrg0mx	309	8	and	and	CC
cord-321013-8pkrg0mx	309	9	functions	function	NNS
cord-321013-8pkrg0mx	309	10	X	x	NN
cord-321013-8pkrg0mx	309	11	-	-	NN
cord-321013-8pkrg0mx	309	12	ray	ray	JJ
cord-321013-8pkrg0mx	309	13	structures	structure	NNS
cord-321013-8pkrg0mx	309	14	of	of	IN
cord-321013-8pkrg0mx	309	15	the	the	DT
cord-321013-8pkrg0mx	309	16	N	N	NNP
cord-321013-8pkrg0mx	309	17	-	-	HYPH
cord-321013-8pkrg0mx	309	18	and	and	CC
cord-321013-8pkrg0mx	309	19	C	c	NN
cord-321013-8pkrg0mx	309	20	-	-	HYPH
cord-321013-8pkrg0mx	309	21	terminal	terminal	NN
cord-321013-8pkrg0mx	309	22	domains	domain	NNS
cord-321013-8pkrg0mx	309	23	of	of	IN
cord-321013-8pkrg0mx	309	24	a	a	DT
cord-321013-8pkrg0mx	309	25	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	309	26	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	309	27	protein	protein	NN
cord-321013-8pkrg0mx	309	28	:	:	:
cord-321013-8pkrg0mx	309	29	Implications	implication	NNS
cord-321013-8pkrg0mx	309	30	for	for	IN
cord-321013-8pkrg0mx	309	31	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	309	32	formation	formation	NN
cord-321013-8pkrg0mx	310	1	The	the	DT
cord-321013-8pkrg0mx	310	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	310	3	protein	protein	NN
cord-321013-8pkrg0mx	310	4	of	of	IN
cord-321013-8pkrg0mx	310	5	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	310	6	infectious	infectious	JJ
cord-321013-8pkrg0mx	310	7	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	310	8	virus	virus	NN
cord-321013-8pkrg0mx	310	9	:	:	:
cord-321013-8pkrg0mx	310	10	Crystal	crystal	NN
cord-321013-8pkrg0mx	310	11	structure	structure	NN
cord-321013-8pkrg0mx	310	12	of	of	IN
cord-321013-8pkrg0mx	310	13	its	-PRON-	PRP$
cord-321013-8pkrg0mx	310	14	N	n	CD
cord-321013-8pkrg0mx	310	15	-	-	HYPH
cord-321013-8pkrg0mx	310	16	terminal	terminal	NN
cord-321013-8pkrg0mx	310	17	domain	domain	NN
cord-321013-8pkrg0mx	310	18	and	and	CC
cord-321013-8pkrg0mx	310	19	multimerization	multimerization	NN
cord-321013-8pkrg0mx	311	1	properties	property	NNS
cord-321013-8pkrg0mx	312	1	Characterisation	Characterisation	NNP
cord-321013-8pkrg0mx	312	2	of	of	IN
cord-321013-8pkrg0mx	312	3	the	the	DT
cord-321013-8pkrg0mx	312	4	RNA	RNA	NNP
cord-321013-8pkrg0mx	312	5	binding	binding	NN
cord-321013-8pkrg0mx	312	6	properties	property	NNS
cord-321013-8pkrg0mx	312	7	of	of	IN
cord-321013-8pkrg0mx	312	8	the	the	DT
cord-321013-8pkrg0mx	312	9	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	312	10	infectious	infectious	JJ
cord-321013-8pkrg0mx	312	11	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	312	12	virus	virus	NN
cord-321013-8pkrg0mx	312	13	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	312	14	protein	protein	NN
cord-321013-8pkrg0mx	312	15	amino	amino	NN
cord-321013-8pkrg0mx	312	16	-	-	HYPH
cord-321013-8pkrg0mx	312	17	terminal	terminal	NN
cord-321013-8pkrg0mx	312	18	region	region	NN
cord-321013-8pkrg0mx	312	19	Amino	amino	NN
cord-321013-8pkrg0mx	312	20	acid	acid	NN
cord-321013-8pkrg0mx	312	21	residues	residue	NNS
cord-321013-8pkrg0mx	312	22	critical	critical	JJ
cord-321013-8pkrg0mx	312	23	for	for	IN
cord-321013-8pkrg0mx	312	24	RNA	rna	NN
cord-321013-8pkrg0mx	312	25	-	-	HYPH
cord-321013-8pkrg0mx	312	26	binding	bind	VBG
cord-321013-8pkrg0mx	312	27	in	in	IN
cord-321013-8pkrg0mx	312	28	the	the	DT
cord-321013-8pkrg0mx	312	29	N	n	CD
cord-321013-8pkrg0mx	312	30	-	-	HYPH
cord-321013-8pkrg0mx	312	31	terminal	terminal	NN
cord-321013-8pkrg0mx	312	32	domain	domain	NN
cord-321013-8pkrg0mx	312	33	of	of	IN
cord-321013-8pkrg0mx	312	34	the	the	DT
cord-321013-8pkrg0mx	312	35	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	312	36	protein	protein	NN
cord-321013-8pkrg0mx	312	37	are	be	VBP
cord-321013-8pkrg0mx	312	38	essential	essential	JJ
cord-321013-8pkrg0mx	312	39	determinants	determinant	NNS
cord-321013-8pkrg0mx	312	40	for	for	IN
cord-321013-8pkrg0mx	312	41	the	the	DT
cord-321013-8pkrg0mx	312	42	infectivity	infectivity	NN
cord-321013-8pkrg0mx	312	43	of	of	IN
cord-321013-8pkrg0mx	312	44	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	312	45	in	in	IN
cord-321013-8pkrg0mx	312	46	cultured	cultured	JJ
cord-321013-8pkrg0mx	312	47	cells	cell	NNS
cord-321013-8pkrg0mx	312	48	Crystal	Crystal	NNP
cord-321013-8pkrg0mx	312	49	structure	structure	NN
cord-321013-8pkrg0mx	312	50	at	at	IN
cord-321013-8pkrg0mx	312	51	1.92	1.92	CD
cord-321013-8pkrg0mx	312	52	A	a	DT
cord-321013-8pkrg0mx	312	53	resolution	resolution	NN
cord-321013-8pkrg0mx	312	54	of	of	IN
cord-321013-8pkrg0mx	312	55	the	the	DT
cord-321013-8pkrg0mx	312	56	RNA	RNA	NNP
cord-321013-8pkrg0mx	312	57	-	-	HYPH
cord-321013-8pkrg0mx	312	58	binding	bind	VBG
cord-321013-8pkrg0mx	312	59	domain	domain	NN
cord-321013-8pkrg0mx	312	60	of	of	IN
cord-321013-8pkrg0mx	312	61	the	the	DT
cord-321013-8pkrg0mx	312	62	U1A	U1A	NNP
cord-321013-8pkrg0mx	312	63	spliceosomal	spliceosomal	NNP
cord-321013-8pkrg0mx	312	64	protein	protein	NN
cord-321013-8pkrg0mx	312	65	complexed	complexe	VBN
cord-321013-8pkrg0mx	312	66	with	with	IN
cord-321013-8pkrg0mx	312	67	an	an	DT
cord-321013-8pkrg0mx	312	68	RNA	RNA	NNP
cord-321013-8pkrg0mx	312	69	hairpin	hairpin	NN
cord-321013-8pkrg0mx	312	70	Crystal	Crystal	NNP
cord-321013-8pkrg0mx	312	71	structure	structure	NN
cord-321013-8pkrg0mx	312	72	of	of	IN
cord-321013-8pkrg0mx	312	73	an	an	DT
cord-321013-8pkrg0mx	312	74	RNA	RNA	NNP
cord-321013-8pkrg0mx	312	75	bacteriophage	bacteriophage	NN
cord-321013-8pkrg0mx	312	76	coat	coat	NN
cord-321013-8pkrg0mx	312	77	protein	protein	NN
cord-321013-8pkrg0mx	312	78	-	-	HYPH
cord-321013-8pkrg0mx	312	79	operator	operator	NN
cord-321013-8pkrg0mx	312	80	complex	complex	JJ
cord-321013-8pkrg0mx	312	81	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	312	82	N	N	NNP
cord-321013-8pkrg0mx	312	83	protein	protein	NN
cord-321013-8pkrg0mx	312	84	N	n	CD
cord-321013-8pkrg0mx	312	85	-	-	HYPH
cord-321013-8pkrg0mx	312	86	terminal	terminal	NN
cord-321013-8pkrg0mx	312	87	domain	domain	NN
cord-321013-8pkrg0mx	312	88	(	(	-LRB-
cord-321013-8pkrg0mx	312	89	NTD	NTD	NNP
cord-321013-8pkrg0mx	312	90	)	)	-RRB-
cord-321013-8pkrg0mx	312	91	specifically	specifically	RB
cord-321013-8pkrg0mx	312	92	binds	bind	VBZ
cord-321013-8pkrg0mx	312	93	the	the	DT
cord-321013-8pkrg0mx	312	94	transcriptional	transcriptional	JJ
cord-321013-8pkrg0mx	312	95	regulatory	regulatory	JJ
cord-321013-8pkrg0mx	312	96	sequence	sequence	NN
cord-321013-8pkrg0mx	312	97	(	(	-LRB-
cord-321013-8pkrg0mx	312	98	TRS	TRS	NNP
cord-321013-8pkrg0mx	312	99	)	)	-RRB-
cord-321013-8pkrg0mx	312	100	and	and	CC
cord-321013-8pkrg0mx	312	101	melts	melt	VBZ
cord-321013-8pkrg0mx	313	1	TRS	TRS	NNP
cord-321013-8pkrg0mx	313	2	-	-	HYPH
cord-321013-8pkrg0mx	313	3	cTRS	cTRS	NNP
cord-321013-8pkrg0mx	313	4	RNA	RNA	NNP
cord-321013-8pkrg0mx	313	5	duplexes	duplex	NNS
cord-321013-8pkrg0mx	313	6	Structures	structure	NNS
cord-321013-8pkrg0mx	313	7	of	of	IN
cord-321013-8pkrg0mx	313	8	the	the	DT
cord-321013-8pkrg0mx	313	9	N	N	NNP
cord-321013-8pkrg0mx	313	10	-	-	HYPH
cord-321013-8pkrg0mx	313	11	and	and	CC
cord-321013-8pkrg0mx	313	12	C	c	NN
cord-321013-8pkrg0mx	313	13	-	-	HYPH
cord-321013-8pkrg0mx	313	14	terminal	terminal	NN
cord-321013-8pkrg0mx	313	15	domains	domain	NNS
cord-321013-8pkrg0mx	313	16	of	of	IN
cord-321013-8pkrg0mx	313	17	MHV	MHV	NNP
cord-321013-8pkrg0mx	313	18	-	-	HYPH
cord-321013-8pkrg0mx	313	19	A59	A59	NNP
cord-321013-8pkrg0mx	313	20	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	313	21	protein	protein	NN
cord-321013-8pkrg0mx	313	22	corroborate	corroborate	VBP
cord-321013-8pkrg0mx	313	23	a	a	DT
cord-321013-8pkrg0mx	313	24	conserved	conserve	VBN
cord-321013-8pkrg0mx	313	25	RNA	rna	NN
cord-321013-8pkrg0mx	313	26	-	-	HYPH
cord-321013-8pkrg0mx	313	27	protein	protein	NN
cord-321013-8pkrg0mx	313	28	binding	binding	NN
cord-321013-8pkrg0mx	313	29	mechanism	mechanism	NN
cord-321013-8pkrg0mx	313	30	in	in	IN
cord-321013-8pkrg0mx	313	31	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	314	1	A	a	DT
cord-321013-8pkrg0mx	314	2	new	new	JJ
cord-321013-8pkrg0mx	314	3	model	model	NN
cord-321013-8pkrg0mx	314	4	for	for	IN
cord-321013-8pkrg0mx	314	5	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	314	6	transcription	transcription	NN
cord-321013-8pkrg0mx	314	7	Sequence	sequence	NN
cord-321013-8pkrg0mx	314	8	motifs	motif	NNS
cord-321013-8pkrg0mx	314	9	involved	involve	VBN
cord-321013-8pkrg0mx	314	10	in	in	IN
cord-321013-8pkrg0mx	314	11	the	the	DT
cord-321013-8pkrg0mx	314	12	regulation	regulation	NN
cord-321013-8pkrg0mx	314	13	of	of	IN
cord-321013-8pkrg0mx	314	14	discontinuous	discontinuous	JJ
cord-321013-8pkrg0mx	314	15	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	314	16	subgenomic	subgenomic	NNP
cord-321013-8pkrg0mx	314	17	RNA	RNA	NNP
cord-321013-8pkrg0mx	314	18	synthesis	synthesis	NN
cord-321013-8pkrg0mx	314	19	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	314	20	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	314	21	protein	protein	NN
cord-321013-8pkrg0mx	314	22	is	be	VBZ
cord-321013-8pkrg0mx	314	23	an	an	DT
cord-321013-8pkrg0mx	314	24	RNA	RNA	NNP
cord-321013-8pkrg0mx	314	25	chaperone	chaperone	NN
cord-321013-8pkrg0mx	314	26	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	314	27	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	314	28	protein	protein	NN
cord-321013-8pkrg0mx	314	29	facilitates	facilitate	VBZ
cord-321013-8pkrg0mx	314	30	template	template	NN
cord-321013-8pkrg0mx	314	31	switching	switching	NN
cord-321013-8pkrg0mx	314	32	and	and	CC
cord-321013-8pkrg0mx	314	33	is	be	VBZ
cord-321013-8pkrg0mx	314	34	required	require	VBN
cord-321013-8pkrg0mx	314	35	for	for	IN
cord-321013-8pkrg0mx	314	36	efficient	efficient	JJ
cord-321013-8pkrg0mx	314	37	transcription	transcription	NN
cord-321013-8pkrg0mx	314	38	HIV-1	HIV-1	NNP
cord-321013-8pkrg0mx	314	39	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	314	40	protein	protein	NN
cord-321013-8pkrg0mx	314	41	as	as	IN
cord-321013-8pkrg0mx	314	42	a	a	DT
cord-321013-8pkrg0mx	314	43	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	314	44	acid	acid	NN
cord-321013-8pkrg0mx	314	45	chaperone	chaperone	NN
cord-321013-8pkrg0mx	314	46	:	:	:
cord-321013-8pkrg0mx	314	47	Spectroscopic	spectroscopic	JJ
cord-321013-8pkrg0mx	314	48	study	study	NN
cord-321013-8pkrg0mx	314	49	of	of	IN
cord-321013-8pkrg0mx	314	50	its	-PRON-	PRP$
cord-321013-8pkrg0mx	314	51	helix	helix	NN
cord-321013-8pkrg0mx	314	52	-	-	HYPH
cord-321013-8pkrg0mx	314	53	destabilizing	destabilize	VBG
cord-321013-8pkrg0mx	314	54	properties	property	NNS
cord-321013-8pkrg0mx	314	55	,	,	,
cord-321013-8pkrg0mx	314	56	structural	structural	JJ
cord-321013-8pkrg0mx	314	57	binding	binding	NN
cord-321013-8pkrg0mx	314	58	specificity	specificity	NN
cord-321013-8pkrg0mx	314	59	,	,	,
cord-321013-8pkrg0mx	314	60	and	and	CC
cord-321013-8pkrg0mx	314	61	annealing	anneal	VBG
cord-321013-8pkrg0mx	314	62	activity	activity	NN
cord-321013-8pkrg0mx	314	63	Adenovirus	Adenovirus	NNP
cord-321013-8pkrg0mx	314	64	DNA	DNA	NNP
cord-321013-8pkrg0mx	314	65	binding	bind	VBG
cord-321013-8pkrg0mx	314	66	protein	protein	NN
cord-321013-8pkrg0mx	314	67	:	:	:
cord-321013-8pkrg0mx	314	68	Helix	helix	NN
cord-321013-8pkrg0mx	314	69	destabilising	destabilising	JJ
cord-321013-8pkrg0mx	314	70	properties	property	NNS
cord-321013-8pkrg0mx	314	71	Identification	identification	NN
cord-321013-8pkrg0mx	314	72	of	of	IN
cord-321013-8pkrg0mx	314	73	in	in	IN
cord-321013-8pkrg0mx	314	74	vivo	vivo	NN
cord-321013-8pkrg0mx	314	75	-	-	HYPH
cord-321013-8pkrg0mx	314	76	interacting	interact	VBG
cord-321013-8pkrg0mx	314	77	domains	domain	NNS
cord-321013-8pkrg0mx	314	78	of	of	IN
cord-321013-8pkrg0mx	314	79	the	the	DT
cord-321013-8pkrg0mx	314	80	murine	murine	JJ
cord-321013-8pkrg0mx	314	81	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	314	82	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	314	83	protein	protein	NN
cord-321013-8pkrg0mx	314	84	Subcellular	Subcellular	NNP
cord-321013-8pkrg0mx	314	85	localization	localization	NN
cord-321013-8pkrg0mx	314	86	of	of	IN
cord-321013-8pkrg0mx	314	87	the	the	DT
cord-321013-8pkrg0mx	314	88	severe	severe	JJ
cord-321013-8pkrg0mx	314	89	acute	acute	JJ
cord-321013-8pkrg0mx	314	90	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	314	91	syndrome	syndrome	NN
cord-321013-8pkrg0mx	314	92	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	314	93	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	314	94	protein	protein	NN
cord-321013-8pkrg0mx	314	95	Specific	specific	JJ
cord-321013-8pkrg0mx	314	96	interaction	interaction	NN
cord-321013-8pkrg0mx	314	97	between	between	IN
cord-321013-8pkrg0mx	314	98	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	314	99	leader	leader	NN
cord-321013-8pkrg0mx	314	100	RNA	RNA	NNP
cord-321013-8pkrg0mx	314	101	and	and	CC
cord-321013-8pkrg0mx	314	102	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	314	103	protein	protein	NN
cord-321013-8pkrg0mx	314	104	Multiple	multiple	JJ
cord-321013-8pkrg0mx	314	105	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	314	106	acid	acid	NN
cord-321013-8pkrg0mx	314	107	binding	bind	VBG
cord-321013-8pkrg0mx	314	108	sites	site	NNS
cord-321013-8pkrg0mx	314	109	and	and	CC
cord-321013-8pkrg0mx	314	110	intrinsic	intrinsic	JJ
cord-321013-8pkrg0mx	314	111	disorder	disorder	NN
cord-321013-8pkrg0mx	314	112	of	of	IN
cord-321013-8pkrg0mx	314	113	severe	severe	JJ
cord-321013-8pkrg0mx	314	114	acute	acute	JJ
cord-321013-8pkrg0mx	314	115	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	314	116	syndrome	syndrome	NN
cord-321013-8pkrg0mx	314	117	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	314	118	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	314	119	protein	protein	NN
cord-321013-8pkrg0mx	314	120	:	:	:
cord-321013-8pkrg0mx	314	121	Implications	implication	NNS
cord-321013-8pkrg0mx	314	122	for	for	IN
cord-321013-8pkrg0mx	314	123	ribonucleocapsid	ribonucleocapsid	NNP
cord-321013-8pkrg0mx	314	124	protein	protein	NN
cord-321013-8pkrg0mx	314	125	packaging	packaging	NN
cord-321013-8pkrg0mx	314	126	Phosphorylation	Phosphorylation	NNP
cord-321013-8pkrg0mx	314	127	of	of	IN
cord-321013-8pkrg0mx	314	128	the	the	DT
cord-321013-8pkrg0mx	314	129	arginine	arginine	NN
cord-321013-8pkrg0mx	314	130	/	/	SYM
cord-321013-8pkrg0mx	314	131	serine	serine	NN
cord-321013-8pkrg0mx	314	132	dipeptide	dipeptide	NN
cord-321013-8pkrg0mx	314	133	-	-	HYPH
cord-321013-8pkrg0mx	314	134	rich	rich	JJ
cord-321013-8pkrg0mx	314	135	motif	motif	NN
cord-321013-8pkrg0mx	314	136	of	of	IN
cord-321013-8pkrg0mx	314	137	the	the	DT
cord-321013-8pkrg0mx	314	138	severe	severe	JJ
cord-321013-8pkrg0mx	314	139	acute	acute	JJ
cord-321013-8pkrg0mx	314	140	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	314	141	syndrome	syndrome	NN
cord-321013-8pkrg0mx	314	142	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	314	143	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	314	144	protein	protein	NN
cord-321013-8pkrg0mx	315	1	modulates	modulate	VBZ
cord-321013-8pkrg0mx	315	2	its	-PRON-	PRP$
cord-321013-8pkrg0mx	315	3	multimerization	multimerization	NN
cord-321013-8pkrg0mx	315	4	,	,	,
cord-321013-8pkrg0mx	315	5	translation	translation	NN
cord-321013-8pkrg0mx	315	6	inhibitory	inhibitory	JJ
cord-321013-8pkrg0mx	315	7	activity	activity	NN
cord-321013-8pkrg0mx	315	8	and	and	CC
cord-321013-8pkrg0mx	315	9	cellular	cellular	JJ
cord-321013-8pkrg0mx	315	10	localization	localization	NN
cord-321013-8pkrg0mx	316	1	The	the	DT
cord-321013-8pkrg0mx	316	2	severe	severe	JJ
cord-321013-8pkrg0mx	316	3	acute	acute	JJ
cord-321013-8pkrg0mx	316	4	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	316	5	syndrome	syndrome	NN
cord-321013-8pkrg0mx	316	6	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	316	7	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	316	8	protein	protein	NN
cord-321013-8pkrg0mx	316	9	is	be	VBZ
cord-321013-8pkrg0mx	316	10	phosphorylated	phosphorylate	VBN
cord-321013-8pkrg0mx	316	11	and	and	CC
cord-321013-8pkrg0mx	316	12	localizes	localize	VBZ
cord-321013-8pkrg0mx	316	13	in	in	IN
cord-321013-8pkrg0mx	316	14	the	the	DT
cord-321013-8pkrg0mx	316	15	cytoplasm	cytoplasm	NN
cord-321013-8pkrg0mx	316	16	by	by	IN
cord-321013-8pkrg0mx	316	17	14	14	CD
cord-321013-8pkrg0mx	316	18	-	-	SYM
cord-321013-8pkrg0mx	316	19	3	3	CD
cord-321013-8pkrg0mx	316	20	-	-	HYPH
cord-321013-8pkrg0mx	316	21	3-mediated	3-mediated	CD
cord-321013-8pkrg0mx	316	22	translocation	translocation	NN
cord-321013-8pkrg0mx	316	23	Structure	Structure	NNP
cord-321013-8pkrg0mx	316	24	of	of	IN
cord-321013-8pkrg0mx	316	25	the	the	DT
cord-321013-8pkrg0mx	316	26	SARS	SARS	NNP
cord-321013-8pkrg0mx	316	27	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	316	28	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	316	29	protein	protein	NN
cord-321013-8pkrg0mx	316	30	RNA	RNA	NNP
cord-321013-8pkrg0mx	316	31	-	-	HYPH
cord-321013-8pkrg0mx	316	32	binding	bind	VBG
cord-321013-8pkrg0mx	316	33	dimerization	dimerization	NN
cord-321013-8pkrg0mx	316	34	domain	domain	NN
cord-321013-8pkrg0mx	317	1	suggests	suggest	VBZ
cord-321013-8pkrg0mx	317	2	a	a	DT
cord-321013-8pkrg0mx	317	3	mechanism	mechanism	NN
cord-321013-8pkrg0mx	317	4	for	for	IN
cord-321013-8pkrg0mx	317	5	helical	helical	JJ
cord-321013-8pkrg0mx	317	6	packaging	packaging	NN
cord-321013-8pkrg0mx	317	7	of	of	IN
cord-321013-8pkrg0mx	317	8	viral	viral	JJ
cord-321013-8pkrg0mx	317	9	RNA	RNA	NNP
cord-321013-8pkrg0mx	318	1	The	the	DT
cord-321013-8pkrg0mx	318	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	318	3	protein	protein	NN
cord-321013-8pkrg0mx	318	4	of	of	IN
cord-321013-8pkrg0mx	318	5	the	the	DT
cord-321013-8pkrg0mx	318	6	SARS	SARS	NNP
cord-321013-8pkrg0mx	318	7	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	318	8	is	be	VBZ
cord-321013-8pkrg0mx	318	9	capable	capable	JJ
cord-321013-8pkrg0mx	318	10	of	of	IN
cord-321013-8pkrg0mx	318	11	self	self	NN
cord-321013-8pkrg0mx	318	12	-	-	HYPH
cord-321013-8pkrg0mx	318	13	association	association	NN
cord-321013-8pkrg0mx	318	14	through	through	IN
cord-321013-8pkrg0mx	318	15	a	a	DT
cord-321013-8pkrg0mx	318	16	C	C	NNP
cord-321013-8pkrg0mx	318	17	-	-	HYPH
cord-321013-8pkrg0mx	318	18	terminal	terminal	NN
cord-321013-8pkrg0mx	318	19	209	209	CD
cord-321013-8pkrg0mx	318	20	amino	amino	NN
cord-321013-8pkrg0mx	318	21	acid	acid	NN
cord-321013-8pkrg0mx	318	22	interaction	interaction	NN
cord-321013-8pkrg0mx	318	23	domain	domain	NN
cord-321013-8pkrg0mx	318	24	Solution	Solution	NNP
cord-321013-8pkrg0mx	318	25	structure	structure	NN
cord-321013-8pkrg0mx	318	26	of	of	IN
cord-321013-8pkrg0mx	318	27	the	the	DT
cord-321013-8pkrg0mx	318	28	c	c	NN
cord-321013-8pkrg0mx	318	29	-	-	HYPH
cord-321013-8pkrg0mx	318	30	terminal	terminal	JJ
cord-321013-8pkrg0mx	318	31	dimerization	dimerization	NN
cord-321013-8pkrg0mx	318	32	domain	domain	NN
cord-321013-8pkrg0mx	318	33	of	of	IN
cord-321013-8pkrg0mx	318	34	SARS	SARS	NNP
cord-321013-8pkrg0mx	318	35	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	318	36	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	318	37	protein	protein	NN
cord-321013-8pkrg0mx	318	38	solved	solve	VBN
cord-321013-8pkrg0mx	318	39	by	by	IN
cord-321013-8pkrg0mx	318	40	the	the	DT
cord-321013-8pkrg0mx	318	41	SAIL	SAIL	NNP
cord-321013-8pkrg0mx	318	42	-	-	HYPH
cord-321013-8pkrg0mx	318	43	NMR	nmr	NN
cord-321013-8pkrg0mx	318	44	method	method	NN
cord-321013-8pkrg0mx	318	45	Theoretical	theoretical	JJ
cord-321013-8pkrg0mx	318	46	aspects	aspect	NNS
cord-321013-8pkrg0mx	318	47	of	of	IN
cord-321013-8pkrg0mx	318	48	virus	virus	NN
cord-321013-8pkrg0mx	318	49	capsid	capsid	NN
cord-321013-8pkrg0mx	318	50	assembly	assembly	NN
cord-321013-8pkrg0mx	318	51	Assembly	Assembly	NNP
cord-321013-8pkrg0mx	318	52	of	of	IN
cord-321013-8pkrg0mx	318	53	severe	severe	JJ
cord-321013-8pkrg0mx	318	54	acute	acute	JJ
cord-321013-8pkrg0mx	318	55	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	318	56	syndrome	syndrome	NN
cord-321013-8pkrg0mx	318	57	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	318	58	RNA	RNA	NNP
cord-321013-8pkrg0mx	318	59	packaging	packaging	NN
cord-321013-8pkrg0mx	318	60	signal	signal	NN
cord-321013-8pkrg0mx	318	61	into	into	IN
cord-321013-8pkrg0mx	318	62	virus	virus	NN
cord-321013-8pkrg0mx	318	63	-	-	HYPH
cord-321013-8pkrg0mx	318	64	like	like	JJ
cord-321013-8pkrg0mx	318	65	particles	particle	NNS
cord-321013-8pkrg0mx	318	66	is	be	VBZ
cord-321013-8pkrg0mx	318	67	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	318	68	dependent	dependent	JJ
cord-321013-8pkrg0mx	318	69	Generation	generation	NN
cord-321013-8pkrg0mx	318	70	of	of	IN
cord-321013-8pkrg0mx	318	71	synthetic	synthetic	JJ
cord-321013-8pkrg0mx	318	72	severe	severe	JJ
cord-321013-8pkrg0mx	318	73	acute	acute	JJ
cord-321013-8pkrg0mx	318	74	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	318	75	syndrome	syndrome	NN
cord-321013-8pkrg0mx	318	76	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	318	77	pseudoparticles	pseudoparticle	NNS
cord-321013-8pkrg0mx	318	78	:	:	:
cord-321013-8pkrg0mx	319	1	Implications	implication	NNS
cord-321013-8pkrg0mx	319	2	for	for	IN
cord-321013-8pkrg0mx	319	3	assembly	assembly	NN
cord-321013-8pkrg0mx	319	4	and	and	CC
cord-321013-8pkrg0mx	319	5	vaccine	vaccine	NN
cord-321013-8pkrg0mx	319	6	production	production	NN
cord-321013-8pkrg0mx	319	7	A	a	DT
cord-321013-8pkrg0mx	319	8	major	major	JJ
cord-321013-8pkrg0mx	319	9	determinant	determinant	NN
cord-321013-8pkrg0mx	319	10	for	for	IN
cord-321013-8pkrg0mx	319	11	membrane	membrane	NN
cord-321013-8pkrg0mx	319	12	protein	protein	NN
cord-321013-8pkrg0mx	319	13	interaction	interaction	NN
cord-321013-8pkrg0mx	319	14	localizes	localize	VBZ
cord-321013-8pkrg0mx	319	15	to	to	IN
cord-321013-8pkrg0mx	319	16	the	the	DT
cord-321013-8pkrg0mx	319	17	carboxy	carboxy	JJ
cord-321013-8pkrg0mx	319	18	-	-	HYPH
cord-321013-8pkrg0mx	319	19	terminal	terminal	NN
cord-321013-8pkrg0mx	319	20	domain	domain	NN
cord-321013-8pkrg0mx	319	21	of	of	IN
cord-321013-8pkrg0mx	319	22	the	the	DT
cord-321013-8pkrg0mx	319	23	mouse	mouse	NN
cord-321013-8pkrg0mx	319	24	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	319	25	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	319	26	protein	protein	NN
cord-321013-8pkrg0mx	319	27	Protein	Protein	NNP
cord-321013-8pkrg0mx	319	28	disorder	disorder	NN
cord-321013-8pkrg0mx	319	29	and	and	CC
cord-321013-8pkrg0mx	319	30	the	the	DT
cord-321013-8pkrg0mx	319	31	evolution	evolution	NN
cord-321013-8pkrg0mx	319	32	of	of	IN
cord-321013-8pkrg0mx	319	33	molecular	molecular	JJ
cord-321013-8pkrg0mx	319	34	recognition	recognition	NN
cord-321013-8pkrg0mx	319	35	:	:	:
cord-321013-8pkrg0mx	319	36	Theory	theory	NN
cord-321013-8pkrg0mx	319	37	,	,	,
cord-321013-8pkrg0mx	319	38	predictions	prediction	NNS
cord-321013-8pkrg0mx	319	39	and	and	CC
cord-321013-8pkrg0mx	319	40	observations	observation	NNS
cord-321013-8pkrg0mx	319	41	Predicting	predict	VBG
cord-321013-8pkrg0mx	319	42	Binding	Binding	NNP
cord-321013-8pkrg0mx	319	43	Regions	region	NNS
cord-321013-8pkrg0mx	319	44	within	within	IN
cord-321013-8pkrg0mx	319	45	Disordered	Disordered	NNP
cord-321013-8pkrg0mx	319	46	Proteins	Proteins	NNPS
cord-321013-8pkrg0mx	319	47	Carboxyl	Carboxyl	NNP
cord-321013-8pkrg0mx	319	48	terminus	terminus	NN
cord-321013-8pkrg0mx	319	49	of	of	IN
cord-321013-8pkrg0mx	319	50	severe	severe	JJ
cord-321013-8pkrg0mx	319	51	acute	acute	JJ
cord-321013-8pkrg0mx	319	52	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	319	53	syndrome	syndrome	NN
cord-321013-8pkrg0mx	319	54	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	319	55	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	319	56	protein	protein	NN
cord-321013-8pkrg0mx	319	57	:	:	:
cord-321013-8pkrg0mx	319	58	Self	Self	NNP
cord-321013-8pkrg0mx	319	59	-	-	HYPH
cord-321013-8pkrg0mx	319	60	association	association	NN
cord-321013-8pkrg0mx	319	61	analysis	analysis	NN
cord-321013-8pkrg0mx	319	62	and	and	CC
cord-321013-8pkrg0mx	319	63	nucleic	nucleic	JJ
cord-321013-8pkrg0mx	319	64	acid	acid	NN
cord-321013-8pkrg0mx	320	1	binding	bind	VBG
cord-321013-8pkrg0mx	320	2	characterization	characterization	NN
cord-321013-8pkrg0mx	321	1	Characterization	characterization	NN
cord-321013-8pkrg0mx	321	2	of	of	IN
cord-321013-8pkrg0mx	321	3	protein	protein	NN
cord-321013-8pkrg0mx	321	4	-	-	HYPH
cord-321013-8pkrg0mx	321	5	protein	protein	NN
cord-321013-8pkrg0mx	321	6	interactions	interaction	NNS
cord-321013-8pkrg0mx	321	7	between	between	IN
cord-321013-8pkrg0mx	321	8	the	the	DT
cord-321013-8pkrg0mx	321	9	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	321	10	protein	protein	NN
cord-321013-8pkrg0mx	321	11	and	and	CC
cord-321013-8pkrg0mx	321	12	membrane	membrane	NN
cord-321013-8pkrg0mx	321	13	protein	protein	NN
cord-321013-8pkrg0mx	321	14	of	of	IN
cord-321013-8pkrg0mx	321	15	the	the	DT
cord-321013-8pkrg0mx	321	16	SARS	SARS	NNP
cord-321013-8pkrg0mx	321	17	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	322	1	The	the	DT
cord-321013-8pkrg0mx	322	2	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	322	3	infectious	infectious	JJ
cord-321013-8pkrg0mx	322	4	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	322	5	virus	virus	NN
cord-321013-8pkrg0mx	322	6	nucleoprotein	nucleoprotein	NNP
cord-321013-8pkrg0mx	322	7	localizes	localize	VBZ
cord-321013-8pkrg0mx	322	8	to	to	IN
cord-321013-8pkrg0mx	322	9	the	the	DT
cord-321013-8pkrg0mx	322	10	nucleolus	nucleolus	NN
cord-321013-8pkrg0mx	322	11	Delineation	delineation	NN
cord-321013-8pkrg0mx	322	12	and	and	CC
cord-321013-8pkrg0mx	322	13	modelling	modelling	NN
cord-321013-8pkrg0mx	322	14	of	of	IN
cord-321013-8pkrg0mx	322	15	a	a	DT
cord-321013-8pkrg0mx	322	16	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	322	17	retention	retention	NN
cord-321013-8pkrg0mx	322	18	signal	signal	NN
cord-321013-8pkrg0mx	322	19	in	in	IN
cord-321013-8pkrg0mx	322	20	the	the	DT
cord-321013-8pkrg0mx	322	21	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	322	22	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	322	23	protein	protein	NN
cord-321013-8pkrg0mx	322	24	Cell	Cell	NNP
cord-321013-8pkrg0mx	322	25	cycle	cycle	NN
cord-321013-8pkrg0mx	322	26	dependent	dependent	JJ
cord-321013-8pkrg0mx	322	27	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	322	28	localization	localization	NN
cord-321013-8pkrg0mx	322	29	of	of	IN
cord-321013-8pkrg0mx	322	30	the	the	DT
cord-321013-8pkrg0mx	322	31	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	322	32	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	322	33	protein	protein	NN
cord-321013-8pkrg0mx	322	34	Localization	Localization	NNP
cord-321013-8pkrg0mx	322	35	to	to	IN
cord-321013-8pkrg0mx	322	36	the	the	DT
cord-321013-8pkrg0mx	322	37	nucleolus	nucleolus	NN
cord-321013-8pkrg0mx	322	38	is	be	VBZ
cord-321013-8pkrg0mx	322	39	a	a	DT
cord-321013-8pkrg0mx	322	40	common	common	JJ
cord-321013-8pkrg0mx	322	41	feature	feature	NN
cord-321013-8pkrg0mx	322	42	of	of	IN
cord-321013-8pkrg0mx	322	43	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	322	44	nucleoproteins	nucleoprotein	NNS
cord-321013-8pkrg0mx	322	45	,	,	,
cord-321013-8pkrg0mx	322	46	and	and	CC
cord-321013-8pkrg0mx	322	47	the	the	DT
cord-321013-8pkrg0mx	322	48	protein	protein	NN
cord-321013-8pkrg0mx	322	49	may	may	MD
cord-321013-8pkrg0mx	322	50	disrupt	disrupt	VB
cord-321013-8pkrg0mx	322	51	host	host	NN
cord-321013-8pkrg0mx	322	52	cell	cell	NN
cord-321013-8pkrg0mx	322	53	division	division	NN
cord-321013-8pkrg0mx	322	54	Intracellular	Intracellular	NNP
cord-321013-8pkrg0mx	322	55	localization	localization	NN
cord-321013-8pkrg0mx	322	56	of	of	IN
cord-321013-8pkrg0mx	322	57	the	the	DT
cord-321013-8pkrg0mx	322	58	severe	severe	JJ
cord-321013-8pkrg0mx	322	59	acute	acute	JJ
cord-321013-8pkrg0mx	322	60	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	322	61	syndrome	syndrome	NN
cord-321013-8pkrg0mx	322	62	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	322	63	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	322	64	protein	protein	NN
cord-321013-8pkrg0mx	322	65	:	:	:
cord-321013-8pkrg0mx	322	66	Absence	absence	NN
cord-321013-8pkrg0mx	322	67	of	of	IN
cord-321013-8pkrg0mx	322	68	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	322	69	accumulation	accumulation	NN
cord-321013-8pkrg0mx	322	70	during	during	IN
cord-321013-8pkrg0mx	322	71	infection	infection	NN
cord-321013-8pkrg0mx	322	72	and	and	CC
cord-321013-8pkrg0mx	322	73	after	after	IN
cord-321013-8pkrg0mx	322	74	expression	expression	NN
cord-321013-8pkrg0mx	322	75	as	as	IN
cord-321013-8pkrg0mx	322	76	a	a	DT
cord-321013-8pkrg0mx	322	77	recombinant	recombinant	JJ
cord-321013-8pkrg0mx	322	78	protein	protein	NN
cord-321013-8pkrg0mx	322	79	in	in	IN
cord-321013-8pkrg0mx	322	80	vero	vero	NNP
cord-321013-8pkrg0mx	322	81	cells	cell	NNS
cord-321013-8pkrg0mx	322	82	Interaction	Interaction	NNP
cord-321013-8pkrg0mx	322	83	of	of	IN
cord-321013-8pkrg0mx	322	84	the	the	DT
cord-321013-8pkrg0mx	322	85	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	322	86	nucleoprotein	nucleoprotein	NNP
cord-321013-8pkrg0mx	322	87	with	with	IN
cord-321013-8pkrg0mx	322	88	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	322	89	antigens	antigen	NNS
cord-321013-8pkrg0mx	322	90	and	and	CC
cord-321013-8pkrg0mx	322	91	the	the	DT
cord-321013-8pkrg0mx	322	92	host	host	NN
cord-321013-8pkrg0mx	322	93	cell	cell	NN
cord-321013-8pkrg0mx	322	94	Human	Human	NNP
cord-321013-8pkrg0mx	322	95	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	322	96	OC43	OC43	NNP
cord-321013-8pkrg0mx	322	97	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	322	98	protein	protein	NN
cord-321013-8pkrg0mx	322	99	binds	bind	VBZ
cord-321013-8pkrg0mx	322	100	microRNA	microRNA	NNP
cord-321013-8pkrg0mx	322	101	9	9	CD
cord-321013-8pkrg0mx	322	102	and	and	CC
cord-321013-8pkrg0mx	322	103	potentiates	potentiate	VBZ
cord-321013-8pkrg0mx	322	104	NF	NF	NNP
cord-321013-8pkrg0mx	322	105	-	-	HYPH
cord-321013-8pkrg0mx	322	106	kappaB	kappaB	NNP
cord-321013-8pkrg0mx	322	107	activation	activation	NN
cord-321013-8pkrg0mx	322	108	Nuclear	Nuclear	NNP
cord-321013-8pkrg0mx	322	109	/	/	SYM
cord-321013-8pkrg0mx	322	110	nucleolar	nucleolar	JJ
cord-321013-8pkrg0mx	322	111	localization	localization	NN
cord-321013-8pkrg0mx	322	112	properties	property	NNS
cord-321013-8pkrg0mx	322	113	of	of	IN
cord-321013-8pkrg0mx	322	114	C	C	NNP
cord-321013-8pkrg0mx	322	115	-	-	HYPH
cord-321013-8pkrg0mx	322	116	terminal	terminal	NNP
cord-321013-8pkrg0mx	322	117	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	322	118	protein	protein	NN
cord-321013-8pkrg0mx	322	119	of	of	IN
cord-321013-8pkrg0mx	322	120	SARS	SARS	NNP
cord-321013-8pkrg0mx	322	121	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	323	1	The	the	DT
cord-321013-8pkrg0mx	323	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	323	3	protein	protein	NN
cord-321013-8pkrg0mx	323	4	of	of	IN
cord-321013-8pkrg0mx	323	5	severe	severe	JJ
cord-321013-8pkrg0mx	323	6	acute	acute	JJ
cord-321013-8pkrg0mx	323	7	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	323	8	syndrome	syndrome	NN
cord-321013-8pkrg0mx	323	9	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	323	10	inhibits	inhibit	VBZ
cord-321013-8pkrg0mx	323	11	cell	cell	NN
cord-321013-8pkrg0mx	323	12	cytokinesis	cytokinesis	NN
cord-321013-8pkrg0mx	323	13	and	and	CC
cord-321013-8pkrg0mx	323	14	proliferation	proliferation	NN
cord-321013-8pkrg0mx	323	15	by	by	IN
cord-321013-8pkrg0mx	323	16	interacting	interact	VBG
cord-321013-8pkrg0mx	323	17	with	with	IN
cord-321013-8pkrg0mx	323	18	translation	translation	NN
cord-321013-8pkrg0mx	323	19	elongation	elongation	NN
cord-321013-8pkrg0mx	323	20	factor	factor	NN
cord-321013-8pkrg0mx	323	21	1alpha	1alpha	CD
cord-321013-8pkrg0mx	323	22	The	the	DT
cord-321013-8pkrg0mx	323	23	Genome	Genome	NNP
cord-321013-8pkrg0mx	323	24	sequence	sequence	NN
cord-321013-8pkrg0mx	323	25	of	of	IN
cord-321013-8pkrg0mx	323	26	the	the	DT
cord-321013-8pkrg0mx	323	27	SARS	SARS	NNP
cord-321013-8pkrg0mx	323	28	-	-	HYPH
cord-321013-8pkrg0mx	323	29	associated	associate	VBN
cord-321013-8pkrg0mx	323	30	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	323	31	Molecular	molecular	JJ
cord-321013-8pkrg0mx	323	32	interactions	interaction	NNS
cord-321013-8pkrg0mx	323	33	in	in	IN
cord-321013-8pkrg0mx	323	34	the	the	DT
cord-321013-8pkrg0mx	323	35	assembly	assembly	NNP
cord-321013-8pkrg0mx	323	36	of	of	IN
cord-321013-8pkrg0mx	323	37	coronaviruses	coronaviruses	NNP
cord-321013-8pkrg0mx	323	38	RNA	RNA	NNP
cord-321013-8pkrg0mx	323	39	-	-	HYPH
cord-321013-8pkrg0mx	323	40	binding	bind	VBG
cord-321013-8pkrg0mx	323	41	proteins	protein	NNS
cord-321013-8pkrg0mx	323	42	of	of	IN
cord-321013-8pkrg0mx	323	43	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	323	44	MHV	mhv	NN
cord-321013-8pkrg0mx	323	45	:	:	:
cord-321013-8pkrg0mx	323	46	Detection	detection	NN
cord-321013-8pkrg0mx	323	47	of	of	IN
cord-321013-8pkrg0mx	323	48	monomeric	monomeric	JJ
cord-321013-8pkrg0mx	323	49	and	and	CC
cord-321013-8pkrg0mx	323	50	multimeric	multimeric	JJ
cord-321013-8pkrg0mx	323	51	N	n	CD
cord-321013-8pkrg0mx	323	52	protein	protein	NN
cord-321013-8pkrg0mx	323	53	with	with	IN
cord-321013-8pkrg0mx	323	54	an	an	DT
cord-321013-8pkrg0mx	323	55	RNA	RNA	NNP
cord-321013-8pkrg0mx	323	56	overlay	overlay	NN
cord-321013-8pkrg0mx	323	57	-	-	HYPH
cord-321013-8pkrg0mx	323	58	protein	protein	NN
cord-321013-8pkrg0mx	323	59	blot	blot	NN
cord-321013-8pkrg0mx	323	60	assay	assay	NN
cord-321013-8pkrg0mx	323	61	Interactions	interaction	NNS
cord-321013-8pkrg0mx	323	62	between	between	IN
cord-321013-8pkrg0mx	323	63	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	323	64	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	323	65	protein	protein	NN
cord-321013-8pkrg0mx	323	66	and	and	CC
cord-321013-8pkrg0mx	323	67	viral	viral	JJ
cord-321013-8pkrg0mx	323	68	RNAs	rna	NNS
cord-321013-8pkrg0mx	323	69	:	:	:
cord-321013-8pkrg0mx	323	70	Implications	implication	NNS
cord-321013-8pkrg0mx	323	71	for	for	IN
cord-321013-8pkrg0mx	323	72	viral	viral	JJ
cord-321013-8pkrg0mx	323	73	transcription	transcription	NN
cord-321013-8pkrg0mx	323	74	Characterization	characterization	NN
cord-321013-8pkrg0mx	323	75	of	of	IN
cord-321013-8pkrg0mx	323	76	N	N	NNP
cord-321013-8pkrg0mx	323	77	protein	protein	NN
cord-321013-8pkrg0mx	323	78	self	self	NN
cord-321013-8pkrg0mx	323	79	-	-	HYPH
cord-321013-8pkrg0mx	323	80	association	association	NN
cord-321013-8pkrg0mx	323	81	in	in	IN
cord-321013-8pkrg0mx	323	82	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	323	83	ribonucleoprotein	ribonucleoprotein	NN
cord-321013-8pkrg0mx	323	84	complexes	complex	NNS
cord-321013-8pkrg0mx	324	1	The	the	DT
cord-321013-8pkrg0mx	324	2	transmissible	transmissible	JJ
cord-321013-8pkrg0mx	324	3	gastroenteritis	gastroenteritis	NN
cord-321013-8pkrg0mx	324	4	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	324	5	contains	contain	VBZ
cord-321013-8pkrg0mx	324	6	a	a	DT
cord-321013-8pkrg0mx	324	7	spherical	spherical	JJ
cord-321013-8pkrg0mx	324	8	core	core	NN
cord-321013-8pkrg0mx	324	9	shell	shell	NN
cord-321013-8pkrg0mx	324	10	consisting	consist	VBG
cord-321013-8pkrg0mx	324	11	of	of	IN
cord-321013-8pkrg0mx	324	12	M	M	NNP
cord-321013-8pkrg0mx	324	13	and	and	CC
cord-321013-8pkrg0mx	324	14	N	n	CD
cord-321013-8pkrg0mx	324	15	proteins	protein	NNS
cord-321013-8pkrg0mx	325	1	The	the	DT
cord-321013-8pkrg0mx	325	2	membrane	membrane	NN
cord-321013-8pkrg0mx	325	3	M	M	NNP
cord-321013-8pkrg0mx	325	4	protein	protein	NN
cord-321013-8pkrg0mx	325	5	carboxy	carboxy	NN
cord-321013-8pkrg0mx	325	6	terminus	terminus	NN
cord-321013-8pkrg0mx	325	7	binds	bind	VBZ
cord-321013-8pkrg0mx	325	8	to	to	IN
cord-321013-8pkrg0mx	325	9	transmissible	transmissible	JJ
cord-321013-8pkrg0mx	325	10	gastroenteritis	gastroenteritis	JJ
cord-321013-8pkrg0mx	325	11	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	325	12	core	core	NN
cord-321013-8pkrg0mx	325	13	and	and	CC
cord-321013-8pkrg0mx	325	14	contributes	contribute	VBZ
cord-321013-8pkrg0mx	325	15	to	to	IN
cord-321013-8pkrg0mx	325	16	core	core	NN
cord-321013-8pkrg0mx	325	17	stability	stability	NN
cord-321013-8pkrg0mx	325	18	Genetic	genetic	JJ
cord-321013-8pkrg0mx	325	19	evidence	evidence	NN
cord-321013-8pkrg0mx	325	20	for	for	IN
cord-321013-8pkrg0mx	325	21	a	a	DT
cord-321013-8pkrg0mx	325	22	structural	structural	JJ
cord-321013-8pkrg0mx	325	23	interaction	interaction	NN
cord-321013-8pkrg0mx	325	24	between	between	IN
cord-321013-8pkrg0mx	325	25	the	the	DT
cord-321013-8pkrg0mx	325	26	carboxy	carboxy	JJ
cord-321013-8pkrg0mx	325	27	termini	terminus	NNS
cord-321013-8pkrg0mx	325	28	of	of	IN
cord-321013-8pkrg0mx	325	29	the	the	DT
cord-321013-8pkrg0mx	325	30	membrane	membrane	NN
cord-321013-8pkrg0mx	325	31	and	and	CC
cord-321013-8pkrg0mx	325	32	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	325	33	proteins	protein	NNS
cord-321013-8pkrg0mx	325	34	of	of	IN
cord-321013-8pkrg0mx	325	35	mouse	mouse	NN
cord-321013-8pkrg0mx	325	36	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	325	37	virus	virus	NN
cord-321013-8pkrg0mx	325	38	Ribonucleoprotein	Ribonucleoprotein	NNP
cord-321013-8pkrg0mx	325	39	-	-	HYPH
cord-321013-8pkrg0mx	325	40	like	like	JJ
cord-321013-8pkrg0mx	325	41	structures	structure	NNS
cord-321013-8pkrg0mx	325	42	from	from	IN
cord-321013-8pkrg0mx	325	43	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	325	44	particles	particle	NNS
cord-321013-8pkrg0mx	325	45	Mass	mass	JJ
cord-321013-8pkrg0mx	325	46	spectroscopic	spectroscopic	JJ
cord-321013-8pkrg0mx	325	47	characterization	characterization	NN
cord-321013-8pkrg0mx	325	48	of	of	IN
cord-321013-8pkrg0mx	325	49	the	the	DT
cord-321013-8pkrg0mx	325	50	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	325	51	infectious	infectious	JJ
cord-321013-8pkrg0mx	325	52	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	325	53	virus	virus	NN
cord-321013-8pkrg0mx	325	54	nucleoprotein	nucleoprotein	NN
cord-321013-8pkrg0mx	325	55	and	and	CC
cord-321013-8pkrg0mx	325	56	elucidation	elucidation	NN
cord-321013-8pkrg0mx	325	57	of	of	IN
cord-321013-8pkrg0mx	325	58	the	the	DT
cord-321013-8pkrg0mx	325	59	role	role	NN
cord-321013-8pkrg0mx	325	60	of	of	IN
cord-321013-8pkrg0mx	325	61	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	325	62	in	in	IN
cord-321013-8pkrg0mx	325	63	RNA	RNA	NNP
cord-321013-8pkrg0mx	325	64	binding	bind	VBG
cord-321013-8pkrg0mx	325	65	by	by	IN
cord-321013-8pkrg0mx	325	66	using	use	VBG
cord-321013-8pkrg0mx	325	67	surface	surface	NN
cord-321013-8pkrg0mx	325	68	plasmon	plasmon	NN
cord-321013-8pkrg0mx	325	69	resonance	resonance	NN
cord-321013-8pkrg0mx	325	70	Ribonucleoprotein	Ribonucleoprotein	NNP
cord-321013-8pkrg0mx	325	71	of	of	IN
cord-321013-8pkrg0mx	325	72	Avian	Avian	NNP
cord-321013-8pkrg0mx	325	73	Infectious	Infectious	NNP
cord-321013-8pkrg0mx	325	74	Bronchitis	Bronchitis	NNP
cord-321013-8pkrg0mx	325	75	Virus	Virus	NNP
cord-321013-8pkrg0mx	325	76	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	325	77	particle	particle	NN
cord-321013-8pkrg0mx	325	78	assembly	assembly	NN
cord-321013-8pkrg0mx	325	79	:	:	:
cord-321013-8pkrg0mx	326	1	Primary	primary	JJ
cord-321013-8pkrg0mx	326	2	structure	structure	NN
cord-321013-8pkrg0mx	326	3	requirements	requirement	NNS
cord-321013-8pkrg0mx	326	4	of	of	IN
cord-321013-8pkrg0mx	326	5	the	the	DT
cord-321013-8pkrg0mx	326	6	membrane	membrane	NN
cord-321013-8pkrg0mx	326	7	protein	protein	NN
cord-321013-8pkrg0mx	326	8	Mapping	mapping	NN
cord-321013-8pkrg0mx	326	9	of	of	IN
cord-321013-8pkrg0mx	326	10	the	the	DT
cord-321013-8pkrg0mx	326	11	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	326	12	membrane	membrane	NN
cord-321013-8pkrg0mx	326	13	protein	protein	NN
cord-321013-8pkrg0mx	326	14	domains	domain	NNS
cord-321013-8pkrg0mx	326	15	involved	involve	VBN
cord-321013-8pkrg0mx	326	16	in	in	IN
cord-321013-8pkrg0mx	326	17	interaction	interaction	NN
cord-321013-8pkrg0mx	326	18	with	with	IN
cord-321013-8pkrg0mx	326	19	the	the	DT
cord-321013-8pkrg0mx	326	20	spike	spike	NN
cord-321013-8pkrg0mx	326	21	protein	protein	NN
cord-321013-8pkrg0mx	327	1	The	the	DT
cord-321013-8pkrg0mx	327	2	budding	bud	VBG
cord-321013-8pkrg0mx	327	3	mechanisms	mechanism	NNS
cord-321013-8pkrg0mx	327	4	of	of	IN
cord-321013-8pkrg0mx	327	5	enveloped	envelop	VBN
cord-321013-8pkrg0mx	327	6	animal	animal	NN
cord-321013-8pkrg0mx	327	7	viruses	virus	NNS
cord-321013-8pkrg0mx	327	8	Nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	327	9	-	-	HYPH
cord-321013-8pkrg0mx	327	10	glycoprotein	glycoprotein	NN
cord-321013-8pkrg0mx	327	11	interactions	interaction	NNS
cord-321013-8pkrg0mx	327	12	required	require	VBN
cord-321013-8pkrg0mx	327	13	for	for	IN
cord-321013-8pkrg0mx	327	14	assembly	assembly	NN
cord-321013-8pkrg0mx	327	15	of	of	IN
cord-321013-8pkrg0mx	327	16	alphaviruses	alphaviruses	NNP
cord-321013-8pkrg0mx	327	17	Spike	Spike	NNP
cord-321013-8pkrg0mx	327	18	protein	protein	NN
cord-321013-8pkrg0mx	327	19	-	-	HYPH
cord-321013-8pkrg0mx	327	20	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	327	21	interactions	interaction	NNS
cord-321013-8pkrg0mx	327	22	drive	drive	VBP
cord-321013-8pkrg0mx	327	23	the	the	DT
cord-321013-8pkrg0mx	327	24	budding	budding	NN
cord-321013-8pkrg0mx	327	25	of	of	IN
cord-321013-8pkrg0mx	327	26	alphaviruses	alphaviruses	NNP
cord-321013-8pkrg0mx	327	27	Isolation	Isolation	NNP
cord-321013-8pkrg0mx	327	28	of	of	IN
cord-321013-8pkrg0mx	327	29	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	327	30	envelope	envelope	NN
cord-321013-8pkrg0mx	327	31	glycoproteins	glycoprotein	NNS
cord-321013-8pkrg0mx	327	32	and	and	CC
cord-321013-8pkrg0mx	327	33	interaction	interaction	NN
cord-321013-8pkrg0mx	327	34	with	with	IN
cord-321013-8pkrg0mx	327	35	the	the	DT
cord-321013-8pkrg0mx	327	36	viral	viral	JJ
cord-321013-8pkrg0mx	327	37	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	327	38	Characterization	characterization	NN
cord-321013-8pkrg0mx	327	39	of	of	IN
cord-321013-8pkrg0mx	327	40	the	the	DT
cord-321013-8pkrg0mx	327	41	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	327	42	M	M	NNP
cord-321013-8pkrg0mx	327	43	protein	protein	NN
cord-321013-8pkrg0mx	327	44	and	and	CC
cord-321013-8pkrg0mx	327	45	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	327	46	interaction	interaction	NN
cord-321013-8pkrg0mx	327	47	in	in	IN
cord-321013-8pkrg0mx	327	48	infected	infected	JJ
cord-321013-8pkrg0mx	327	49	cells	cell	NNS
cord-321013-8pkrg0mx	327	50	Assembly	Assembly	NNP
cord-321013-8pkrg0mx	327	51	of	of	IN
cord-321013-8pkrg0mx	327	52	animal	animal	NN
cord-321013-8pkrg0mx	327	53	viruses	virus	NNS
cord-321013-8pkrg0mx	327	54	at	at	IN
cord-321013-8pkrg0mx	327	55	cellular	cellular	JJ
cord-321013-8pkrg0mx	327	56	membranes	membrane	NNS
cord-321013-8pkrg0mx	327	57	Protein	Protein	NNP
cord-321013-8pkrg0mx	327	58	localization	localization	NN
cord-321013-8pkrg0mx	327	59	and	and	CC
cord-321013-8pkrg0mx	327	60	virus	virus	NN
cord-321013-8pkrg0mx	327	61	assembly	assembly	NN
cord-321013-8pkrg0mx	327	62	at	at	IN
cord-321013-8pkrg0mx	327	63	intracellular	intracellular	JJ
cord-321013-8pkrg0mx	327	64	membranes	membrane	NNS
cord-321013-8pkrg0mx	327	65	Replication	replication	NN
cord-321013-8pkrg0mx	327	66	of	of	IN
cord-321013-8pkrg0mx	327	67	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	327	68	MHV	mhv	NN
cord-321013-8pkrg0mx	327	69	-	-	HYPH
cord-321013-8pkrg0mx	327	70	A59	A59	NNP
cord-321013-8pkrg0mx	327	71	in	in	IN
cord-321013-8pkrg0mx	327	72	sac	sac	NN
cord-321013-8pkrg0mx	327	73	-	-	HYPH
cord-321013-8pkrg0mx	327	74	cells	cell	NNS
cord-321013-8pkrg0mx	327	75	:	:	:
cord-321013-8pkrg0mx	327	76	Determination	determination	NN
cord-321013-8pkrg0mx	327	77	of	of	IN
cord-321013-8pkrg0mx	327	78	the	the	DT
cord-321013-8pkrg0mx	327	79	first	first	JJ
cord-321013-8pkrg0mx	327	80	site	site	NN
cord-321013-8pkrg0mx	327	81	of	of	IN
cord-321013-8pkrg0mx	327	82	budding	budding	NN
cord-321013-8pkrg0mx	327	83	of	of	IN
cord-321013-8pkrg0mx	327	84	progeny	progeny	JJ
cord-321013-8pkrg0mx	327	85	virions	virion	NNS
cord-321013-8pkrg0mx	327	86	Identification	identification	NN
cord-321013-8pkrg0mx	327	87	and	and	CC
cord-321013-8pkrg0mx	327	88	characterization	characterization	NN
cord-321013-8pkrg0mx	327	89	of	of	IN
cord-321013-8pkrg0mx	327	90	a	a	DT
cord-321013-8pkrg0mx	327	91	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	327	92	packaging	packaging	NN
cord-321013-8pkrg0mx	327	93	signal	signal	NN
cord-321013-8pkrg0mx	328	1	A	a	DT
cord-321013-8pkrg0mx	328	2	domain	domain	NN
cord-321013-8pkrg0mx	328	3	at	at	IN
cord-321013-8pkrg0mx	328	4	the	the	DT
cord-321013-8pkrg0mx	328	5	3	3	CD
cord-321013-8pkrg0mx	328	6	'	'	NN
cord-321013-8pkrg0mx	328	7	end	end	NN
cord-321013-8pkrg0mx	328	8	of	of	IN
cord-321013-8pkrg0mx	328	9	the	the	DT
cord-321013-8pkrg0mx	328	10	polymerase	polymerase	NN
cord-321013-8pkrg0mx	328	11	gene	gene	NN
cord-321013-8pkrg0mx	328	12	is	be	VBZ
cord-321013-8pkrg0mx	328	13	essential	essential	JJ
cord-321013-8pkrg0mx	328	14	for	for	IN
cord-321013-8pkrg0mx	328	15	encapsidation	encapsidation	NN
cord-321013-8pkrg0mx	328	16	of	of	IN
cord-321013-8pkrg0mx	328	17	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	328	18	defective	defective	JJ
cord-321013-8pkrg0mx	328	19	interfering	interfere	VBG
cord-321013-8pkrg0mx	328	20	RNAs	rna	NNS
cord-321013-8pkrg0mx	329	1	Murine	murine	JJ
cord-321013-8pkrg0mx	329	2	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	329	3	packaging	packaging	NN
cord-321013-8pkrg0mx	329	4	signal	signal	NN
cord-321013-8pkrg0mx	329	5	confers	confer	VBZ
cord-321013-8pkrg0mx	329	6	packaging	packaging	NN
cord-321013-8pkrg0mx	329	7	to	to	IN
cord-321013-8pkrg0mx	329	8	nonviral	nonviral	NNP
cord-321013-8pkrg0mx	329	9	RNA	RNA	NNP
cord-321013-8pkrg0mx	329	10	Nucleocapsid	Nucleocapsid	NNP
cord-321013-8pkrg0mx	329	11	-	-	HYPH
cord-321013-8pkrg0mx	329	12	independent	independent	JJ
cord-321013-8pkrg0mx	329	13	specific	specific	JJ
cord-321013-8pkrg0mx	329	14	viral	viral	JJ
cord-321013-8pkrg0mx	329	15	RNA	RNA	NNP
cord-321013-8pkrg0mx	329	16	packaging	packaging	NN
cord-321013-8pkrg0mx	329	17	via	via	IN
cord-321013-8pkrg0mx	329	18	viral	viral	JJ
cord-321013-8pkrg0mx	329	19	envelope	envelope	NN
cord-321013-8pkrg0mx	329	20	protein	protein	NN
cord-321013-8pkrg0mx	329	21	and	and	CC
cord-321013-8pkrg0mx	329	22	viral	viral	JJ
cord-321013-8pkrg0mx	329	23	RNA	RNA	NNP
cord-321013-8pkrg0mx	329	24	signal	signal	NN
cord-321013-8pkrg0mx	329	25	Characterization	characterization	NN
cord-321013-8pkrg0mx	329	26	of	of	IN
cord-321013-8pkrg0mx	329	27	a	a	DT
cord-321013-8pkrg0mx	329	28	novel	novel	JJ
cord-321013-8pkrg0mx	329	29	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	329	30	associated	associate	VBN
cord-321013-8pkrg0mx	329	31	with	with	IN
cord-321013-8pkrg0mx	329	32	severe	severe	JJ
cord-321013-8pkrg0mx	329	33	acute	acute	JJ
cord-321013-8pkrg0mx	329	34	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	329	35	syndrome	syndrome	NN
cord-321013-8pkrg0mx	329	36	Mammalian	mammalian	JJ
cord-321013-8pkrg0mx	329	37	two	two	CD
cord-321013-8pkrg0mx	329	38	-	-	HYPH
cord-321013-8pkrg0mx	329	39	hybrid	hybrid	NN
cord-321013-8pkrg0mx	329	40	system	system	NN
cord-321013-8pkrg0mx	329	41	:	:	:
cord-321013-8pkrg0mx	329	42	A	a	DT
cord-321013-8pkrg0mx	329	43	complementary	complementary	JJ
cord-321013-8pkrg0mx	329	44	approach	approach	NN
cord-321013-8pkrg0mx	329	45	to	to	IN
cord-321013-8pkrg0mx	329	46	the	the	DT
cord-321013-8pkrg0mx	329	47	yeast	yeast	NN
cord-321013-8pkrg0mx	329	48	two	two	CD
cord-321013-8pkrg0mx	329	49	-	-	HYPH
cord-321013-8pkrg0mx	329	50	hybrid	hybrid	NN
cord-321013-8pkrg0mx	329	51	system	system	NN
cord-321013-8pkrg0mx	329	52	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	329	53	M	M	NNP
cord-321013-8pkrg0mx	329	54	proteins	protein	NNS
cord-321013-8pkrg0mx	329	55	accumulate	accumulate	VBP
cord-321013-8pkrg0mx	329	56	in	in	IN
cord-321013-8pkrg0mx	329	57	the	the	DT
cord-321013-8pkrg0mx	329	58	Golgi	Golgi	NNP
cord-321013-8pkrg0mx	329	59	complex	complex	NN
cord-321013-8pkrg0mx	329	60	beyond	beyond	IN
cord-321013-8pkrg0mx	329	61	the	the	DT
cord-321013-8pkrg0mx	329	62	site	site	NN
cord-321013-8pkrg0mx	329	63	of	of	IN
cord-321013-8pkrg0mx	329	64	virion	virion	NN
cord-321013-8pkrg0mx	329	65	budding	bud	VBG
cord-321013-8pkrg0mx	329	66	Nucleocapsid	nucleocapsid	JJ
cord-321013-8pkrg0mx	329	67	-	-	HYPH
cord-321013-8pkrg0mx	329	68	independent	independent	JJ
cord-321013-8pkrg0mx	329	69	assembly	assembly	NN
cord-321013-8pkrg0mx	329	70	of	of	IN
cord-321013-8pkrg0mx	329	71	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	329	72	-	-	HYPH
cord-321013-8pkrg0mx	329	73	like	like	JJ
cord-321013-8pkrg0mx	329	74	particles	particle	NNS
cord-321013-8pkrg0mx	329	75	by	by	IN
cord-321013-8pkrg0mx	329	76	co	co	NN
cord-321013-8pkrg0mx	329	77	-	-	NN
cord-321013-8pkrg0mx	329	78	expression	expression	NN
cord-321013-8pkrg0mx	329	79	of	of	IN
cord-321013-8pkrg0mx	329	80	viral	viral	JJ
cord-321013-8pkrg0mx	329	81	envelope	envelope	NN
cord-321013-8pkrg0mx	329	82	protein	protein	NN
cord-321013-8pkrg0mx	329	83	genes	gene	NNS
cord-321013-8pkrg0mx	330	1	Infectious	infectious	JJ
cord-321013-8pkrg0mx	330	2	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	330	3	virus	virus	NN
cord-321013-8pkrg0mx	330	4	E	e	NN
cord-321013-8pkrg0mx	330	5	protein	protein	NN
cord-321013-8pkrg0mx	330	6	is	be	VBZ
cord-321013-8pkrg0mx	330	7	targeted	target	VBN
cord-321013-8pkrg0mx	330	8	to	to	IN
cord-321013-8pkrg0mx	330	9	the	the	DT
cord-321013-8pkrg0mx	330	10	Golgi	Golgi	NNP
cord-321013-8pkrg0mx	330	11	complex	complex	NN
cord-321013-8pkrg0mx	330	12	and	and	CC
cord-321013-8pkrg0mx	330	13	directs	direct	VBZ
cord-321013-8pkrg0mx	330	14	release	release	NN
cord-321013-8pkrg0mx	330	15	of	of	IN
cord-321013-8pkrg0mx	330	16	virus	virus	NN
cord-321013-8pkrg0mx	330	17	-	-	HYPH
cord-321013-8pkrg0mx	330	18	like	like	JJ
cord-321013-8pkrg0mx	330	19	particles	particle	NNS
cord-321013-8pkrg0mx	330	20	Sequencing	sequence	VBG
cord-321013-8pkrg0mx	330	21	of	of	IN
cord-321013-8pkrg0mx	330	22	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	330	23	IBV	IBV	NNP
cord-321013-8pkrg0mx	330	24	genomic	genomic	JJ
cord-321013-8pkrg0mx	330	25	RNA	rna	NN
cord-321013-8pkrg0mx	330	26	:	:	:
cord-321013-8pkrg0mx	330	27	Three	three	CD
cord-321013-8pkrg0mx	330	28	open	open	JJ
cord-321013-8pkrg0mx	330	29	reading	reading	NN
cord-321013-8pkrg0mx	330	30	frames	frame	NNS
cord-321013-8pkrg0mx	330	31	in	in	IN
cord-321013-8pkrg0mx	330	32	the	the	DT
cord-321013-8pkrg0mx	330	33	5	5	CD
cord-321013-8pkrg0mx	330	34	'	'	''
cord-321013-8pkrg0mx	330	35	'	'	``
cord-321013-8pkrg0mx	330	36	unique	unique	JJ
cord-321013-8pkrg0mx	330	37	'	'	''
cord-321013-8pkrg0mx	330	38	region	region	NN
cord-321013-8pkrg0mx	330	39	of	of	IN
cord-321013-8pkrg0mx	330	40	mRNA	mRNA	NNP
cord-321013-8pkrg0mx	330	41	D	D	NNP
cord-321013-8pkrg0mx	330	42	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	330	43	pseudoparticles	pseudoparticle	NNS
cord-321013-8pkrg0mx	330	44	formed	form	VBN
cord-321013-8pkrg0mx	330	45	with	with	IN
cord-321013-8pkrg0mx	330	46	recombinant	recombinant	JJ
cord-321013-8pkrg0mx	330	47	M	M	NNP
cord-321013-8pkrg0mx	330	48	and	and	CC
cord-321013-8pkrg0mx	330	49	E	e	NN
cord-321013-8pkrg0mx	330	50	proteins	protein	NNS
cord-321013-8pkrg0mx	330	51	induce	induce	VBP
cord-321013-8pkrg0mx	330	52	alpha	alpha	NN
cord-321013-8pkrg0mx	330	53	interferon	interferon	NN
cord-321013-8pkrg0mx	330	54	synthesis	synthesis	NN
cord-321013-8pkrg0mx	330	55	by	by	IN
cord-321013-8pkrg0mx	330	56	leukocytes	leukocyte	NNS
cord-321013-8pkrg0mx	330	57	The	the	DT
cord-321013-8pkrg0mx	330	58	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	330	59	E	e	NN
cord-321013-8pkrg0mx	330	60	protein	protein	NN
cord-321013-8pkrg0mx	330	61	:	:	:
cord-321013-8pkrg0mx	330	62	Assembly	assembly	NN
cord-321013-8pkrg0mx	330	63	and	and	CC
cord-321013-8pkrg0mx	330	64	beyond	beyond	IN
cord-321013-8pkrg0mx	330	65	Envelope	Envelope	NNP
cord-321013-8pkrg0mx	330	66	protein	protein	NN
cord-321013-8pkrg0mx	330	67	palmitoylations	palmitoylation	NNS
cord-321013-8pkrg0mx	330	68	are	be	VBP
cord-321013-8pkrg0mx	330	69	crucial	crucial	JJ
cord-321013-8pkrg0mx	330	70	for	for	IN
cord-321013-8pkrg0mx	330	71	murine	murine	JJ
cord-321013-8pkrg0mx	330	72	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	330	73	assembly	assembly	NN
cord-321013-8pkrg0mx	331	1	The	the	DT
cord-321013-8pkrg0mx	331	2	M	M	NNP
cord-321013-8pkrg0mx	331	3	,	,	,
cord-321013-8pkrg0mx	331	4	E	E	NNP
cord-321013-8pkrg0mx	331	5	,	,	,
cord-321013-8pkrg0mx	331	6	and	and	CC
cord-321013-8pkrg0mx	331	7	N	n	CD
cord-321013-8pkrg0mx	331	8	structural	structural	JJ
cord-321013-8pkrg0mx	331	9	proteins	protein	NNS
cord-321013-8pkrg0mx	331	10	of	of	IN
cord-321013-8pkrg0mx	331	11	the	the	DT
cord-321013-8pkrg0mx	331	12	severe	severe	JJ
cord-321013-8pkrg0mx	331	13	acute	acute	JJ
cord-321013-8pkrg0mx	331	14	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	331	15	syndrome	syndrome	NN
cord-321013-8pkrg0mx	331	16	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	331	17	are	be	VBP
cord-321013-8pkrg0mx	331	18	required	require	VBN
cord-321013-8pkrg0mx	331	19	for	for	IN
cord-321013-8pkrg0mx	331	20	efficient	efficient	JJ
cord-321013-8pkrg0mx	331	21	assembly	assembly	NN
cord-321013-8pkrg0mx	331	22	,	,	,
cord-321013-8pkrg0mx	331	23	trafficking	trafficking	NN
cord-321013-8pkrg0mx	331	24	,	,	,
cord-321013-8pkrg0mx	331	25	and	and	CC
cord-321013-8pkrg0mx	331	26	release	release	NN
cord-321013-8pkrg0mx	331	27	of	of	IN
cord-321013-8pkrg0mx	331	28	virus	virus	NN
cord-321013-8pkrg0mx	331	29	-	-	HYPH
cord-321013-8pkrg0mx	331	30	like	like	JJ
cord-321013-8pkrg0mx	331	31	particles	particle	NNS
cord-321013-8pkrg0mx	331	32	The	the	DT
cord-321013-8pkrg0mx	331	33	hydrophobic	hydrophobic	JJ
cord-321013-8pkrg0mx	331	34	domain	domain	NN
cord-321013-8pkrg0mx	331	35	of	of	IN
cord-321013-8pkrg0mx	331	36	infectious	infectious	JJ
cord-321013-8pkrg0mx	331	37	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	331	38	virus	virus	NN
cord-321013-8pkrg0mx	331	39	E	e	NN
cord-321013-8pkrg0mx	331	40	protein	protein	NN
cord-321013-8pkrg0mx	331	41	alters	alter	VBZ
cord-321013-8pkrg0mx	331	42	the	the	DT
cord-321013-8pkrg0mx	331	43	host	host	NN
cord-321013-8pkrg0mx	331	44	secretory	secretory	NN
cord-321013-8pkrg0mx	331	45	pathway	pathway	NN
cord-321013-8pkrg0mx	331	46	and	and	CC
cord-321013-8pkrg0mx	331	47	is	be	VBZ
cord-321013-8pkrg0mx	331	48	important	important	JJ
cord-321013-8pkrg0mx	331	49	for	for	IN
cord-321013-8pkrg0mx	331	50	release	release	NN
cord-321013-8pkrg0mx	331	51	of	of	IN
cord-321013-8pkrg0mx	331	52	infectious	infectious	JJ
cord-321013-8pkrg0mx	331	53	virus	virus	NN
cord-321013-8pkrg0mx	331	54	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	331	55	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	331	56	protein	protein	NN
cord-321013-8pkrg0mx	331	57	.	.	.
cord-321013-8pkrg0mx	332	1	RNA	RNA	NNP
cord-321013-8pkrg0mx	332	2	interactions	interaction	NNS
cord-321013-8pkrg0mx	332	3	Characterization	characterization	NN
cord-321013-8pkrg0mx	332	4	of	of	IN
cord-321013-8pkrg0mx	332	5	two	two	CD
cord-321013-8pkrg0mx	332	6	RNA	RNA	NNP
cord-321013-8pkrg0mx	332	7	polymerase	polymerase	NN
cord-321013-8pkrg0mx	332	8	activities	activity	NNS
cord-321013-8pkrg0mx	332	9	induced	induce	VBN
cord-321013-8pkrg0mx	332	10	by	by	IN
cord-321013-8pkrg0mx	332	11	mouse	mouse	NN
cord-321013-8pkrg0mx	332	12	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	332	13	virus	virus	NN
cord-321013-8pkrg0mx	332	14	Isolation	isolation	NN
cord-321013-8pkrg0mx	332	15	and	and	CC
cord-321013-8pkrg0mx	332	16	identification	identification	NN
cord-321013-8pkrg0mx	332	17	of	of	IN
cord-321013-8pkrg0mx	332	18	virus	virus	NN
cord-321013-8pkrg0mx	332	19	-	-	HYPH
cord-321013-8pkrg0mx	332	20	specific	specific	JJ
cord-321013-8pkrg0mx	332	21	mRNAs	mRNAs	NNPS
cord-321013-8pkrg0mx	332	22	in	in	IN
cord-321013-8pkrg0mx	332	23	cells	cell	NNS
cord-321013-8pkrg0mx	332	24	infected	infect	VBN
cord-321013-8pkrg0mx	332	25	with	with	IN
cord-321013-8pkrg0mx	332	26	mouse	mouse	NN
cord-321013-8pkrg0mx	332	27	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	332	28	virus	virus	NN
cord-321013-8pkrg0mx	332	29	(	(	-LRB-
cord-321013-8pkrg0mx	332	30	MHV	MHV	NNP
cord-321013-8pkrg0mx	332	31	-	-	HYPH
cord-321013-8pkrg0mx	332	32	A59	A59	NNP
cord-321013-8pkrg0mx	332	33	)	)	-RRB-
cord-321013-8pkrg0mx	333	1	The	the	DT
cord-321013-8pkrg0mx	333	2	nucleoprotein	nucleoprotein	NN
cord-321013-8pkrg0mx	333	3	is	be	VBZ
cord-321013-8pkrg0mx	333	4	required	require	VBN
cord-321013-8pkrg0mx	333	5	for	for	IN
cord-321013-8pkrg0mx	333	6	efficient	efficient	JJ
cord-321013-8pkrg0mx	333	7	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	333	8	genome	genome	NN
cord-321013-8pkrg0mx	333	9	replication	replication	NN
cord-321013-8pkrg0mx	333	10	Selective	selective	JJ
cord-321013-8pkrg0mx	333	11	replication	replication	NN
cord-321013-8pkrg0mx	333	12	of	of	IN
cord-321013-8pkrg0mx	333	13	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	333	14	genomes	genome	NNS
cord-321013-8pkrg0mx	333	15	that	that	WDT
cord-321013-8pkrg0mx	333	16	express	express	VBP
cord-321013-8pkrg0mx	333	17	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	333	18	protein	protein	NN
cord-321013-8pkrg0mx	333	19	Viral	Viral	NNP
cord-321013-8pkrg0mx	333	20	replicase	replicase	NN
cord-321013-8pkrg0mx	333	21	gene	gene	NN
cord-321013-8pkrg0mx	333	22	products	product	NNS
cord-321013-8pkrg0mx	333	23	suffice	suffice	VBP
cord-321013-8pkrg0mx	333	24	for	for	IN
cord-321013-8pkrg0mx	333	25	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	333	26	discontinuous	discontinuous	JJ
cord-321013-8pkrg0mx	333	27	transcription	transcription	NN
cord-321013-8pkrg0mx	333	28	Reverse	reverse	NN
cord-321013-8pkrg0mx	333	29	genetics	genetics	NN
cord-321013-8pkrg0mx	333	30	system	system	NN
cord-321013-8pkrg0mx	333	31	for	for	IN
cord-321013-8pkrg0mx	333	32	the	the	DT
cord-321013-8pkrg0mx	333	33	avian	avian	JJ
cord-321013-8pkrg0mx	333	34	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	333	35	infectious	infectious	JJ
cord-321013-8pkrg0mx	333	36	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	333	37	virus	virus	NN
cord-321013-8pkrg0mx	333	38	Systematic	systematic	JJ
cord-321013-8pkrg0mx	333	39	assembly	assembly	NN
cord-321013-8pkrg0mx	333	40	of	of	IN
cord-321013-8pkrg0mx	333	41	a	a	DT
cord-321013-8pkrg0mx	333	42	full	full	JJ
cord-321013-8pkrg0mx	333	43	-	-	HYPH
cord-321013-8pkrg0mx	333	44	length	length	NN
cord-321013-8pkrg0mx	333	45	infectious	infectious	JJ
cord-321013-8pkrg0mx	333	46	cDNA	cdna	NN
cord-321013-8pkrg0mx	333	47	of	of	IN
cord-321013-8pkrg0mx	333	48	mouse	mouse	NNP
cord-321013-8pkrg0mx	333	49	hepatitis	hepatitis	NNP
cord-321013-8pkrg0mx	333	50	virus	virus	NN
cord-321013-8pkrg0mx	333	51	strain	strain	VBP
cord-321013-8pkrg0mx	333	52	A59	A59	NNP
cord-321013-8pkrg0mx	333	53	Strategy	Strategy	NNP
cord-321013-8pkrg0mx	333	54	for	for	IN
cord-321013-8pkrg0mx	333	55	systematic	systematic	JJ
cord-321013-8pkrg0mx	333	56	assembly	assembly	NN
cord-321013-8pkrg0mx	333	57	of	of	IN
cord-321013-8pkrg0mx	333	58	large	large	JJ
cord-321013-8pkrg0mx	333	59	RNA	RNA	NNP
cord-321013-8pkrg0mx	333	60	and	and	CC
cord-321013-8pkrg0mx	333	61	DNA	dna	NN
cord-321013-8pkrg0mx	333	62	genomes	genome	NNS
cord-321013-8pkrg0mx	333	63	:	:	:
cord-321013-8pkrg0mx	333	64	Transmissible	transmissible	JJ
cord-321013-8pkrg0mx	333	65	gastroenteritis	gastroenteritis	NN
cord-321013-8pkrg0mx	333	66	virus	virus	NN
cord-321013-8pkrg0mx	333	67	model	model	NN
cord-321013-8pkrg0mx	333	68	Reverse	reverse	VB
cord-321013-8pkrg0mx	333	69	genetics	genetics	NN
cord-321013-8pkrg0mx	333	70	with	with	IN
cord-321013-8pkrg0mx	333	71	a	a	DT
cord-321013-8pkrg0mx	333	72	full	full	JJ
cord-321013-8pkrg0mx	333	73	-	-	HYPH
cord-321013-8pkrg0mx	333	74	length	length	NN
cord-321013-8pkrg0mx	333	75	infectious	infectious	JJ
cord-321013-8pkrg0mx	333	76	cDNA	cdna	NN
cord-321013-8pkrg0mx	333	77	of	of	IN
cord-321013-8pkrg0mx	333	78	severe	severe	JJ
cord-321013-8pkrg0mx	333	79	acute	acute	JJ
cord-321013-8pkrg0mx	333	80	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	333	81	syndrome	syndrome	NN
cord-321013-8pkrg0mx	333	82	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	334	1	The	the	DT
cord-321013-8pkrg0mx	334	2	putative	putative	JJ
cord-321013-8pkrg0mx	334	3	helicase	helicase	NN
cord-321013-8pkrg0mx	334	4	of	of	IN
cord-321013-8pkrg0mx	334	5	the	the	DT
cord-321013-8pkrg0mx	334	6	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	334	7	mouse	mouse	NN
cord-321013-8pkrg0mx	334	8	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	334	9	virus	virus	NN
cord-321013-8pkrg0mx	334	10	is	be	VBZ
cord-321013-8pkrg0mx	334	11	processed	process	VBN
cord-321013-8pkrg0mx	334	12	from	from	IN
cord-321013-8pkrg0mx	334	13	the	the	DT
cord-321013-8pkrg0mx	334	14	replicase	replicase	NNP
cord-321013-8pkrg0mx	334	15	gene	gene	NNP
cord-321013-8pkrg0mx	334	16	polyprotein	polyprotein	NNP
cord-321013-8pkrg0mx	334	17	and	and	CC
cord-321013-8pkrg0mx	334	18	localizes	localize	VBZ
cord-321013-8pkrg0mx	334	19	in	in	IN
cord-321013-8pkrg0mx	334	20	complexes	complex	NNS
cord-321013-8pkrg0mx	334	21	that	that	WDT
cord-321013-8pkrg0mx	334	22	are	be	VBP
cord-321013-8pkrg0mx	334	23	active	active	JJ
cord-321013-8pkrg0mx	334	24	in	in	IN
cord-321013-8pkrg0mx	334	25	viral	viral	JJ
cord-321013-8pkrg0mx	334	26	RNA	RNA	NNP
cord-321013-8pkrg0mx	334	27	synthesis	synthesis	NN
cord-321013-8pkrg0mx	334	28	Mouse	Mouse	NNP
cord-321013-8pkrg0mx	334	29	hepatitis	hepatitis	NNP
cord-321013-8pkrg0mx	334	30	virus	virus	NN
cord-321013-8pkrg0mx	334	31	replicase	replicase	NN
cord-321013-8pkrg0mx	334	32	proteins	protein	NNS
cord-321013-8pkrg0mx	334	33	associate	associate	VBP
cord-321013-8pkrg0mx	334	34	with	with	IN
cord-321013-8pkrg0mx	334	35	two	two	CD
cord-321013-8pkrg0mx	334	36	distinct	distinct	JJ
cord-321013-8pkrg0mx	334	37	populations	population	NNS
cord-321013-8pkrg0mx	334	38	of	of	IN
cord-321013-8pkrg0mx	334	39	intracellular	intracellular	JJ
cord-321013-8pkrg0mx	334	40	membranes	membrane	NNS
cord-321013-8pkrg0mx	335	1	The	the	DT
cord-321013-8pkrg0mx	335	2	intracellular	intracellular	JJ
cord-321013-8pkrg0mx	335	3	sites	site	NNS
cord-321013-8pkrg0mx	335	4	of	of	IN
cord-321013-8pkrg0mx	335	5	early	early	JJ
cord-321013-8pkrg0mx	335	6	replication	replication	NN
cord-321013-8pkrg0mx	335	7	and	and	CC
cord-321013-8pkrg0mx	335	8	budding	budding	NN
cord-321013-8pkrg0mx	335	9	of	of	IN
cord-321013-8pkrg0mx	335	10	SARS	SARS	NNP
cord-321013-8pkrg0mx	335	11	-	-	HYPH
cord-321013-8pkrg0mx	335	12	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	335	13	Localization	Localization	NNP
cord-321013-8pkrg0mx	335	14	of	of	IN
cord-321013-8pkrg0mx	335	15	mouse	mouse	NN
cord-321013-8pkrg0mx	335	16	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	335	17	virus	virus	NN
cord-321013-8pkrg0mx	335	18	nonstructural	nonstructural	JJ
cord-321013-8pkrg0mx	335	19	proteins	protein	NNS
cord-321013-8pkrg0mx	335	20	and	and	CC
cord-321013-8pkrg0mx	335	21	RNA	RNA	NNP
cord-321013-8pkrg0mx	335	22	synthesis	synthesis	NN
cord-321013-8pkrg0mx	335	23	indicates	indicate	VBZ
cord-321013-8pkrg0mx	335	24	a	a	DT
cord-321013-8pkrg0mx	335	25	role	role	NN
cord-321013-8pkrg0mx	335	26	for	for	IN
cord-321013-8pkrg0mx	335	27	late	late	JJ
cord-321013-8pkrg0mx	335	28	endosomes	endosome	NNS
cord-321013-8pkrg0mx	335	29	in	in	IN
cord-321013-8pkrg0mx	335	30	viral	viral	JJ
cord-321013-8pkrg0mx	335	31	replication	replication	NN
cord-321013-8pkrg0mx	335	32	Optimization	optimization	NN
cord-321013-8pkrg0mx	335	33	of	of	IN
cord-321013-8pkrg0mx	335	34	targeted	target	VBN
cord-321013-8pkrg0mx	335	35	RNA	RNA	NNP
cord-321013-8pkrg0mx	335	36	recombination	recombination	NN
cord-321013-8pkrg0mx	335	37	and	and	CC
cord-321013-8pkrg0mx	335	38	mapping	mapping	NN
cord-321013-8pkrg0mx	335	39	of	of	IN
cord-321013-8pkrg0mx	335	40	a	a	DT
cord-321013-8pkrg0mx	335	41	novel	novel	JJ
cord-321013-8pkrg0mx	335	42	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	335	43	gene	gene	NN
cord-321013-8pkrg0mx	335	44	mutation	mutation	NN
cord-321013-8pkrg0mx	335	45	in	in	IN
cord-321013-8pkrg0mx	335	46	the	the	DT
cord-321013-8pkrg0mx	335	47	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	335	48	mouse	mouse	NN
cord-321013-8pkrg0mx	335	49	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	335	50	virus	virus	NN
cord-321013-8pkrg0mx	335	51	Characterization	characterization	NN
cord-321013-8pkrg0mx	335	52	of	of	IN
cord-321013-8pkrg0mx	335	53	a	a	DT
cord-321013-8pkrg0mx	335	54	critical	critical	JJ
cord-321013-8pkrg0mx	335	55	interaction	interaction	NN
cord-321013-8pkrg0mx	335	56	between	between	IN
cord-321013-8pkrg0mx	335	57	the	the	DT
cord-321013-8pkrg0mx	335	58	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	335	59	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	335	60	protein	protein	NN
cord-321013-8pkrg0mx	335	61	and	and	CC
cord-321013-8pkrg0mx	335	62	nonstructural	nonstructural	JJ
cord-321013-8pkrg0mx	335	63	protein	protein	NNP
cord-321013-8pkrg0mx	335	64	3	3	CD
cord-321013-8pkrg0mx	335	65	of	of	IN
cord-321013-8pkrg0mx	335	66	the	the	DT
cord-321013-8pkrg0mx	335	67	viral	viral	JJ
cord-321013-8pkrg0mx	335	68	replicase	replicase	NN
cord-321013-8pkrg0mx	335	69	-	-	HYPH
cord-321013-8pkrg0mx	335	70	transcriptase	transcriptase	NN
cord-321013-8pkrg0mx	335	71	complex	complex	NN
cord-321013-8pkrg0mx	336	1	A	a	DT
cord-321013-8pkrg0mx	336	2	contemporary	contemporary	JJ
cord-321013-8pkrg0mx	336	3	view	view	NN
cord-321013-8pkrg0mx	336	4	of	of	IN
cord-321013-8pkrg0mx	336	5	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	336	6	transcription	transcription	NN
cord-321013-8pkrg0mx	336	7	Genetic	genetic	JJ
cord-321013-8pkrg0mx	336	8	interactions	interaction	NNS
cord-321013-8pkrg0mx	336	9	between	between	IN
cord-321013-8pkrg0mx	336	10	an	an	DT
cord-321013-8pkrg0mx	336	11	essential	essential	JJ
cord-321013-8pkrg0mx	336	12	3	3	NNP
cord-321013-8pkrg0mx	336	13	'	'	NN
cord-321013-8pkrg0mx	336	14	cis	cis	NNP
cord-321013-8pkrg0mx	336	15	-	-	HYPH
cord-321013-8pkrg0mx	336	16	acting	act	VBG
cord-321013-8pkrg0mx	336	17	RNA	RNA	NNP
cord-321013-8pkrg0mx	336	18	pseudoknot	pseudoknot	NNP
cord-321013-8pkrg0mx	336	19	,	,	,
cord-321013-8pkrg0mx	336	20	replicase	replicase	NNP
cord-321013-8pkrg0mx	336	21	gene	gene	NN
cord-321013-8pkrg0mx	336	22	products	product	NNS
cord-321013-8pkrg0mx	336	23	,	,	,
cord-321013-8pkrg0mx	336	24	and	and	CC
cord-321013-8pkrg0mx	336	25	the	the	DT
cord-321013-8pkrg0mx	336	26	extreme	extreme	JJ
cord-321013-8pkrg0mx	336	27	3	3	CD
cord-321013-8pkrg0mx	336	28	'	'	''
cord-321013-8pkrg0mx	336	29	end	end	NN
cord-321013-8pkrg0mx	336	30	of	of	IN
cord-321013-8pkrg0mx	336	31	the	the	DT
cord-321013-8pkrg0mx	336	32	mouse	mouse	NN
cord-321013-8pkrg0mx	336	33	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	336	34	genome	genome	NN
cord-321013-8pkrg0mx	336	35	Replication	replication	NN
cord-321013-8pkrg0mx	336	36	of	of	IN
cord-321013-8pkrg0mx	336	37	murine	murine	JJ
cord-321013-8pkrg0mx	336	38	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	336	39	virus	virus	NN
cord-321013-8pkrg0mx	336	40	is	be	VBZ
cord-321013-8pkrg0mx	336	41	regulated	regulate	VBN
cord-321013-8pkrg0mx	336	42	by	by	IN
cord-321013-8pkrg0mx	336	43	papain	papain	NN
cord-321013-8pkrg0mx	336	44	-	-	HYPH
cord-321013-8pkrg0mx	336	45	like	like	JJ
cord-321013-8pkrg0mx	336	46	proteinase	proteinase	NN
cord-321013-8pkrg0mx	336	47	1	1	CD
cord-321013-8pkrg0mx	336	48	processing	processing	NN
cord-321013-8pkrg0mx	336	49	of	of	IN
cord-321013-8pkrg0mx	336	50	nonstructural	nonstructural	JJ
cord-321013-8pkrg0mx	336	51	proteins	protein	NNS
cord-321013-8pkrg0mx	336	52	1	1	CD
cord-321013-8pkrg0mx	336	53	,	,	,
cord-321013-8pkrg0mx	336	54	2	2	CD
cord-321013-8pkrg0mx	336	55	,	,	,
cord-321013-8pkrg0mx	336	56	and	and	CC
cord-321013-8pkrg0mx	336	57	3	3	CD
cord-321013-8pkrg0mx	336	58	The	the	DT
cord-321013-8pkrg0mx	336	59	ubiquitous	ubiquitous	JJ
cord-321013-8pkrg0mx	336	60	nature	nature	NN
cord-321013-8pkrg0mx	336	61	of	of	IN
cord-321013-8pkrg0mx	336	62	RNA	RNA	NNP
cord-321013-8pkrg0mx	336	63	chaperone	chaperone	NN
cord-321013-8pkrg0mx	336	64	proteins	protein	NNS
cord-321013-8pkrg0mx	336	65	RNA	RNA	NNP
cord-321013-8pkrg0mx	336	66	chaperones	chaperone	NNS
cord-321013-8pkrg0mx	336	67	and	and	CC
cord-321013-8pkrg0mx	336	68	the	the	DT
cord-321013-8pkrg0mx	336	69	RNA	RNA	NNP
cord-321013-8pkrg0mx	336	70	folding	folding	NN
cord-321013-8pkrg0mx	336	71	problem	problem	NN
cord-321013-8pkrg0mx	336	72	Murine	murine	JJ
cord-321013-8pkrg0mx	336	73	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	336	74	nonstructural	nonstructural	JJ
cord-321013-8pkrg0mx	336	75	protein	protein	NN
cord-321013-8pkrg0mx	336	76	p28	p28	CD
cord-321013-8pkrg0mx	336	77	arrests	arrest	NNS
cord-321013-8pkrg0mx	336	78	cell	cell	NN
cord-321013-8pkrg0mx	336	79	cycle	cycle	NN
cord-321013-8pkrg0mx	336	80	in	in	IN
cord-321013-8pkrg0mx	336	81	G0	G0	NNP
cord-321013-8pkrg0mx	336	82	/	/	SYM
cord-321013-8pkrg0mx	336	83	G1	G1	NNP
cord-321013-8pkrg0mx	336	84	phase	phase	NN
cord-321013-8pkrg0mx	337	1	Murine	murine	JJ
cord-321013-8pkrg0mx	337	2	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	337	3	replication	replication	NN
cord-321013-8pkrg0mx	337	4	induces	induce	VBZ
cord-321013-8pkrg0mx	337	5	cell	cell	NN
cord-321013-8pkrg0mx	337	6	cycle	cycle	NN
cord-321013-8pkrg0mx	337	7	arrest	arrest	NN
cord-321013-8pkrg0mx	337	8	in	in	IN
cord-321013-8pkrg0mx	337	9	G0	G0	NNP
cord-321013-8pkrg0mx	337	10	/	/	SYM
cord-321013-8pkrg0mx	337	11	G1	G1	NNP
cord-321013-8pkrg0mx	337	12	phase	phase	NN
cord-321013-8pkrg0mx	337	13	Extraction	extraction	NN
cord-321013-8pkrg0mx	337	14	and	and	CC
cord-321013-8pkrg0mx	337	15	analysis	analysis	NN
cord-321013-8pkrg0mx	337	16	of	of	IN
cord-321013-8pkrg0mx	337	17	diagnostically	diagnostically	RB
cord-321013-8pkrg0mx	337	18	useful	useful	JJ
cord-321013-8pkrg0mx	337	19	proteins	protein	NNS
cord-321013-8pkrg0mx	337	20	from	from	IN
cord-321013-8pkrg0mx	337	21	formalin	formalin	NN
cord-321013-8pkrg0mx	337	22	-	-	HYPH
cord-321013-8pkrg0mx	337	23	fixed	fix	VBN
cord-321013-8pkrg0mx	337	24	,	,	,
cord-321013-8pkrg0mx	337	25	paraffin	paraffin	NN
cord-321013-8pkrg0mx	337	26	-	-	HYPH
cord-321013-8pkrg0mx	337	27	embedded	embed	VBN
cord-321013-8pkrg0mx	337	28	tissue	tissue	NN
cord-321013-8pkrg0mx	337	29	sections	section	NNS
cord-321013-8pkrg0mx	337	30	Perturbation	perturbation	NN
cord-321013-8pkrg0mx	337	31	of	of	IN
cord-321013-8pkrg0mx	337	32	cell	cell	NN
cord-321013-8pkrg0mx	337	33	cycle	cycle	NN
cord-321013-8pkrg0mx	337	34	progression	progression	NN
cord-321013-8pkrg0mx	337	35	and	and	CC
cord-321013-8pkrg0mx	337	36	cellular	cellular	JJ
cord-321013-8pkrg0mx	337	37	gene	gene	NN
cord-321013-8pkrg0mx	337	38	expression	expression	NN
cord-321013-8pkrg0mx	337	39	as	as	IN
cord-321013-8pkrg0mx	337	40	a	a	DT
cord-321013-8pkrg0mx	337	41	function	function	NN
cord-321013-8pkrg0mx	337	42	of	of	IN
cord-321013-8pkrg0mx	337	43	herpes	herpes	NN
cord-321013-8pkrg0mx	337	44	simplex	simplex	NN
cord-321013-8pkrg0mx	337	45	virus	virus	NN
cord-321013-8pkrg0mx	337	46	ICP0	ICP0	NNP
cord-321013-8pkrg0mx	337	47	Herpes	Herpes	NNP
cord-321013-8pkrg0mx	337	48	simplex	simplex	NN
cord-321013-8pkrg0mx	337	49	virus	virus	NN
cord-321013-8pkrg0mx	337	50	type	type	NN
cord-321013-8pkrg0mx	337	51	1	1	CD
cord-321013-8pkrg0mx	337	52	immediate	immediate	JJ
cord-321013-8pkrg0mx	337	53	-	-	HYPH
cord-321013-8pkrg0mx	337	54	early	early	JJ
cord-321013-8pkrg0mx	337	55	protein	protein	NN
cord-321013-8pkrg0mx	337	56	Vmw110	vmw110	NN
cord-321013-8pkrg0mx	337	57	inhibits	inhibit	VBZ
cord-321013-8pkrg0mx	337	58	progression	progression	NN
cord-321013-8pkrg0mx	337	59	of	of	IN
cord-321013-8pkrg0mx	337	60	cells	cell	NNS
cord-321013-8pkrg0mx	337	61	through	through	IN
cord-321013-8pkrg0mx	337	62	mitosis	mitosis	NN
cord-321013-8pkrg0mx	337	63	and	and	CC
cord-321013-8pkrg0mx	337	64	from	from	IN
cord-321013-8pkrg0mx	337	65	G(1	G(1	NNP
cord-321013-8pkrg0mx	337	66	)	)	-RRB-
cord-321013-8pkrg0mx	337	67	into	into	IN
cord-321013-8pkrg0mx	337	68	S	S	NNP
cord-321013-8pkrg0mx	337	69	phase	phase	NN
cord-321013-8pkrg0mx	337	70	of	of	IN
cord-321013-8pkrg0mx	337	71	the	the	DT
cord-321013-8pkrg0mx	337	72	cell	cell	NN
cord-321013-8pkrg0mx	337	73	cycle	cycle	NN
cord-321013-8pkrg0mx	337	74	Human	Human	NNP
cord-321013-8pkrg0mx	337	75	cytomegalovirus	cytomegalovirus	NN
cord-321013-8pkrg0mx	337	76	86-kilodalton	86-kilodalton	CD
cord-321013-8pkrg0mx	337	77	IE2	ie2	JJ
cord-321013-8pkrg0mx	337	78	protein	protein	NN
cord-321013-8pkrg0mx	337	79	blocks	block	VBZ
cord-321013-8pkrg0mx	337	80	cell	cell	NN
cord-321013-8pkrg0mx	337	81	cycle	cycle	NN
cord-321013-8pkrg0mx	337	82	progression	progression	NN
cord-321013-8pkrg0mx	337	83	in	in	IN
cord-321013-8pkrg0mx	337	84	G(1	G(1	NNP
cord-321013-8pkrg0mx	337	85	)	)	-RRB-
cord-321013-8pkrg0mx	338	1	Human	human	JJ
cord-321013-8pkrg0mx	338	2	cytomegalovirus	cytomegalovirus	NN
cord-321013-8pkrg0mx	338	3	UL69	UL69	NNP
cord-321013-8pkrg0mx	338	4	protein	protein	NN
cord-321013-8pkrg0mx	338	5	induces	induce	VBZ
cord-321013-8pkrg0mx	338	6	cells	cell	NNS
cord-321013-8pkrg0mx	338	7	to	to	TO
cord-321013-8pkrg0mx	338	8	accumulate	accumulate	VB
cord-321013-8pkrg0mx	338	9	in	in	IN
cord-321013-8pkrg0mx	338	10	G1	G1	NNP
cord-321013-8pkrg0mx	338	11	phase	phase	NN
cord-321013-8pkrg0mx	338	12	of	of	IN
cord-321013-8pkrg0mx	338	13	the	the	DT
cord-321013-8pkrg0mx	338	14	cell	cell	NN
cord-321013-8pkrg0mx	338	15	cycle	cycle	NN
cord-321013-8pkrg0mx	339	1	The	the	DT
cord-321013-8pkrg0mx	339	2	Epstein	Epstein	NNP
cord-321013-8pkrg0mx	339	3	-	-	HYPH
cord-321013-8pkrg0mx	339	4	Barr	Barr	NNP
cord-321013-8pkrg0mx	339	5	virus	virus	NN
cord-321013-8pkrg0mx	339	6	bZIP	bzip	CD
cord-321013-8pkrg0mx	339	7	transcription	transcription	NN
cord-321013-8pkrg0mx	339	8	factor	factor	NN
cord-321013-8pkrg0mx	340	1	Zta	zta	NN
cord-321013-8pkrg0mx	340	2	causes	cause	VBZ
cord-321013-8pkrg0mx	340	3	G0	G0	NNP
cord-321013-8pkrg0mx	340	4	/	/	SYM
cord-321013-8pkrg0mx	340	5	G1	G1	NNP
cord-321013-8pkrg0mx	340	6	cell	cell	NN
cord-321013-8pkrg0mx	340	7	cycle	cycle	NN
cord-321013-8pkrg0mx	340	8	arrest	arrest	NN
cord-321013-8pkrg0mx	340	9	through	through	IN
cord-321013-8pkrg0mx	340	10	induction	induction	NN
cord-321013-8pkrg0mx	340	11	of	of	IN
cord-321013-8pkrg0mx	340	12	cyclin	cyclin	NN
cord-321013-8pkrg0mx	340	13	-	-	HYPH
cord-321013-8pkrg0mx	340	14	dependent	dependent	JJ
cord-321013-8pkrg0mx	340	15	kinase	kinase	NN
cord-321013-8pkrg0mx	340	16	inhibitors	inhibitor	NNS
cord-321013-8pkrg0mx	341	1	Coronavirus	Coronavirus	NNP
cord-321013-8pkrg0mx	341	2	infection	infection	NN
cord-321013-8pkrg0mx	341	3	induces	induce	VBZ
cord-321013-8pkrg0mx	341	4	DNA	dna	NN
cord-321013-8pkrg0mx	341	5	replication	replication	NN
cord-321013-8pkrg0mx	341	6	stress	stress	NN
cord-321013-8pkrg0mx	341	7	partly	partly	RB
cord-321013-8pkrg0mx	341	8	through	through	IN
cord-321013-8pkrg0mx	341	9	interaction	interaction	NN
cord-321013-8pkrg0mx	341	10	of	of	IN
cord-321013-8pkrg0mx	341	11	its	-PRON-	PRP$
cord-321013-8pkrg0mx	341	12	nonstructural	nonstructural	JJ
cord-321013-8pkrg0mx	341	13	protein	protein	NN
cord-321013-8pkrg0mx	341	14	13	13	CD
cord-321013-8pkrg0mx	341	15	with	with	IN
cord-321013-8pkrg0mx	341	16	the	the	DT
cord-321013-8pkrg0mx	341	17	p125	p125	NNP
cord-321013-8pkrg0mx	341	18	subunit	subunit	NN
cord-321013-8pkrg0mx	341	19	of	of	IN
cord-321013-8pkrg0mx	341	20	DNA	dna	NN
cord-321013-8pkrg0mx	341	21	polymerase	polymerase	NN
cord-321013-8pkrg0mx	341	22	delta	delta	NN
cord-321013-8pkrg0mx	342	1	The	the	DT
cord-321013-8pkrg0mx	342	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	342	3	protein	protein	NN
cord-321013-8pkrg0mx	342	4	of	of	IN
cord-321013-8pkrg0mx	342	5	severe	severe	JJ
cord-321013-8pkrg0mx	342	6	acute	acute	JJ
cord-321013-8pkrg0mx	342	7	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	342	8	syndrome	syndrome	NN
cord-321013-8pkrg0mx	342	9	-	-	HYPH
cord-321013-8pkrg0mx	342	10	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	342	11	inhibits	inhibit	VBZ
cord-321013-8pkrg0mx	342	12	the	the	DT
cord-321013-8pkrg0mx	342	13	activity	activity	NN
cord-321013-8pkrg0mx	342	14	of	of	IN
cord-321013-8pkrg0mx	342	15	cyclin	cyclin	JJ
cord-321013-8pkrg0mx	342	16	-	-	HYPH
cord-321013-8pkrg0mx	342	17	cyclin	cyclin	NN
cord-321013-8pkrg0mx	342	18	-	-	HYPH
cord-321013-8pkrg0mx	342	19	dependent	dependent	JJ
cord-321013-8pkrg0mx	342	20	kinase	kinase	NN
cord-321013-8pkrg0mx	342	21	complex	complex	NN
cord-321013-8pkrg0mx	342	22	and	and	CC
cord-321013-8pkrg0mx	342	23	blocks	block	VBZ
cord-321013-8pkrg0mx	342	24	S	s	NN
cord-321013-8pkrg0mx	342	25	phase	phase	NN
cord-321013-8pkrg0mx	342	26	progression	progression	NN
cord-321013-8pkrg0mx	342	27	in	in	IN
cord-321013-8pkrg0mx	342	28	mammalian	mammalian	JJ
cord-321013-8pkrg0mx	342	29	cells	cell	NNS
cord-321013-8pkrg0mx	342	30	Stress	stress	NN
cord-321013-8pkrg0mx	342	31	granules	granule	NNS
cord-321013-8pkrg0mx	342	32	:	:	:
cord-321013-8pkrg0mx	343	1	Sites	site	NNS
cord-321013-8pkrg0mx	343	2	of	of	IN
cord-321013-8pkrg0mx	343	3	mRNA	mRNA	NNP
cord-321013-8pkrg0mx	343	4	triage	triage	NN
cord-321013-8pkrg0mx	343	5	that	that	WDT
cord-321013-8pkrg0mx	343	6	regulate	regulate	VBP
cord-321013-8pkrg0mx	343	7	mRNA	mrna	NN
cord-321013-8pkrg0mx	343	8	stability	stability	NN
cord-321013-8pkrg0mx	343	9	and	and	CC
cord-321013-8pkrg0mx	343	10	translatability	translatability	NN
cord-321013-8pkrg0mx	343	11	Molecular	molecular	JJ
cord-321013-8pkrg0mx	343	12	surveillance	surveillance	NN
cord-321013-8pkrg0mx	343	13	of	of	IN
cord-321013-8pkrg0mx	343	14	enterovirus	enterovirus	NN
cord-321013-8pkrg0mx	343	15	and	and	CC
cord-321013-8pkrg0mx	343	16	norwalk	norwalk	NNP
cord-321013-8pkrg0mx	343	17	-	-	HYPH
cord-321013-8pkrg0mx	343	18	like	like	JJ
cord-321013-8pkrg0mx	343	19	virus	virus	NN
cord-321013-8pkrg0mx	343	20	in	in	IN
cord-321013-8pkrg0mx	343	21	oysters	oyster	NNS
cord-321013-8pkrg0mx	343	22	relocated	relocate	VBN
cord-321013-8pkrg0mx	343	23	to	to	IN
cord-321013-8pkrg0mx	343	24	a	a	DT
cord-321013-8pkrg0mx	343	25	municipal	municipal	JJ
cord-321013-8pkrg0mx	343	26	-	-	HYPH
cord-321013-8pkrg0mx	343	27	sewage	sewage	NN
cord-321013-8pkrg0mx	343	28	-	-	HYPH
cord-321013-8pkrg0mx	343	29	impacted	impact	VBN
cord-321013-8pkrg0mx	343	30	gulf	gulf	NNP
cord-321013-8pkrg0mx	343	31	estuary	estuary	NNP
cord-321013-8pkrg0mx	343	32	Mouse	Mouse	NNP
cord-321013-8pkrg0mx	343	33	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	343	34	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	343	35	replication	replication	NN
cord-321013-8pkrg0mx	343	36	induces	induce	VBZ
cord-321013-8pkrg0mx	343	37	host	host	NN
cord-321013-8pkrg0mx	343	38	translational	translational	JJ
cord-321013-8pkrg0mx	343	39	shutoff	shutoff	NN
cord-321013-8pkrg0mx	343	40	and	and	CC
cord-321013-8pkrg0mx	343	41	mRNA	mrna	NN
cord-321013-8pkrg0mx	343	42	decay	decay	NN
cord-321013-8pkrg0mx	343	43	,	,	,
cord-321013-8pkrg0mx	343	44	with	with	IN
cord-321013-8pkrg0mx	343	45	concomitant	concomitant	JJ
cord-321013-8pkrg0mx	343	46	formation	formation	NN
cord-321013-8pkrg0mx	343	47	of	of	IN
cord-321013-8pkrg0mx	343	48	stress	stress	NN
cord-321013-8pkrg0mx	343	49	granules	granule	NNS
cord-321013-8pkrg0mx	343	50	and	and	CC
cord-321013-8pkrg0mx	343	51	processing	process	VBG
cord-321013-8pkrg0mx	343	52	bodies	body	NNS
cord-321013-8pkrg0mx	343	53	cis	cis	NNP
cord-321013-8pkrg0mx	343	54	-	-	HYPH
cord-321013-8pkrg0mx	343	55	acting	acting	NN
cord-321013-8pkrg0mx	343	56	sequences	sequence	NNS
cord-321013-8pkrg0mx	343	57	required	require	VBN
cord-321013-8pkrg0mx	343	58	for	for	IN
cord-321013-8pkrg0mx	343	59	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	343	60	infectious	infectious	JJ
cord-321013-8pkrg0mx	343	61	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	343	62	virus	virus	NN
cord-321013-8pkrg0mx	343	63	defective	defective	JJ
cord-321013-8pkrg0mx	343	64	-	-	HYPH
cord-321013-8pkrg0mx	343	65	RNA	rna	NN
cord-321013-8pkrg0mx	343	66	replication	replication	NN
cord-321013-8pkrg0mx	343	67	and	and	CC
cord-321013-8pkrg0mx	343	68	packaging	package	VBG
cord-321013-8pkrg0mx	343	69	The	the	DT
cord-321013-8pkrg0mx	343	70	nature	nature	NN
cord-321013-8pkrg0mx	343	71	of	of	IN
cord-321013-8pkrg0mx	343	72	the	the	DT
cord-321013-8pkrg0mx	343	73	transition	transition	NN
cord-321013-8pkrg0mx	343	74	state	state	NN
cord-321013-8pkrg0mx	343	75	for	for	IN
cord-321013-8pkrg0mx	343	76	enzyme	enzyme	NN
cord-321013-8pkrg0mx	343	77	-	-	HYPH
cord-321013-8pkrg0mx	343	78	catalyzed	catalyze	VBN
cord-321013-8pkrg0mx	343	79	phosphoryl	phosphoryl	NN
cord-321013-8pkrg0mx	343	80	transfer	transfer	NN
cord-321013-8pkrg0mx	343	81	.	.	.
cord-321013-8pkrg0mx	344	1	Hydrolysis	hydrolysis	NN
cord-321013-8pkrg0mx	344	2	of	of	IN
cord-321013-8pkrg0mx	344	3	O	o	NN
cord-321013-8pkrg0mx	344	4	-	-	HYPH
cord-321013-8pkrg0mx	344	5	aryl	aryl	NN
cord-321013-8pkrg0mx	344	6	phosphorothioates	phosphorothioate	NNS
cord-321013-8pkrg0mx	344	7	by	by	IN
cord-321013-8pkrg0mx	344	8	alkaline	alkaline	JJ
cord-321013-8pkrg0mx	344	9	phosphatase	phosphatase	NN
cord-321013-8pkrg0mx	345	1	The	the	DT
cord-321013-8pkrg0mx	345	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	345	3	protein	protein	NN
cord-321013-8pkrg0mx	345	4	of	of	IN
cord-321013-8pkrg0mx	345	5	coronavirus	coronavirus	NNP
cord-321013-8pkrg0mx	345	6	mouse	mouse	NN
cord-321013-8pkrg0mx	345	7	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	345	8	virus	virus	NN
cord-321013-8pkrg0mx	345	9	interacts	interact	VBZ
cord-321013-8pkrg0mx	345	10	with	with	IN
cord-321013-8pkrg0mx	345	11	the	the	DT
cord-321013-8pkrg0mx	345	12	cellular	cellular	JJ
cord-321013-8pkrg0mx	345	13	heterogeneous	heterogeneous	JJ
cord-321013-8pkrg0mx	345	14	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	345	15	ribonucleoprotein	ribonucleoprotein	NN
cord-321013-8pkrg0mx	345	16	A1	A1	NNP
cord-321013-8pkrg0mx	345	17	in	in	IN
cord-321013-8pkrg0mx	345	18	vitro	vitro	FW
cord-321013-8pkrg0mx	345	19	and	and	CC
cord-321013-8pkrg0mx	346	1	in	in	IN
cord-321013-8pkrg0mx	346	2	vivo	vivo	NNP
cord-321013-8pkrg0mx	346	3	Human	human	JJ
cord-321013-8pkrg0mx	346	4	immunodeficiency	immunodeficiency	NN
cord-321013-8pkrg0mx	346	5	virus	virus	NN
cord-321013-8pkrg0mx	346	6	type	type	NN
cord-321013-8pkrg0mx	346	7	1-neutralizing	1-neutralizing	CD
cord-321013-8pkrg0mx	346	8	monoclonal	monoclonal	JJ
cord-321013-8pkrg0mx	346	9	antibody	antibody	NN
cord-321013-8pkrg0mx	346	10	2F5	2f5	CD
cord-321013-8pkrg0mx	346	11	is	be	VBZ
cord-321013-8pkrg0mx	346	12	multispecific	multispecific	JJ
cord-321013-8pkrg0mx	346	13	for	for	IN
cord-321013-8pkrg0mx	346	14	sequences	sequence	NNS
cord-321013-8pkrg0mx	346	15	flanking	flank	VBG
cord-321013-8pkrg0mx	346	16	the	the	DT
cord-321013-8pkrg0mx	346	17	DKW	DKW	NNP
cord-321013-8pkrg0mx	346	18	core	core	NN
cord-321013-8pkrg0mx	346	19	epitope	epitope	NN
cord-321013-8pkrg0mx	346	20	Translation	translation	NN
cord-321013-8pkrg0mx	346	21	elongation	elongation	NN
cord-321013-8pkrg0mx	346	22	factor	factor	NN
cord-321013-8pkrg0mx	346	23	1A	1a	NN
cord-321013-8pkrg0mx	346	24	is	be	VBZ
cord-321013-8pkrg0mx	346	25	essential	essential	JJ
cord-321013-8pkrg0mx	346	26	for	for	IN
cord-321013-8pkrg0mx	346	27	regulation	regulation	NN
cord-321013-8pkrg0mx	346	28	of	of	IN
cord-321013-8pkrg0mx	346	29	the	the	DT
cord-321013-8pkrg0mx	346	30	actin	actin	NN
cord-321013-8pkrg0mx	346	31	cytoskeleton	cytoskeleton	NN
cord-321013-8pkrg0mx	346	32	and	and	CC
cord-321013-8pkrg0mx	346	33	cell	cell	NN
cord-321013-8pkrg0mx	346	34	morphology	morphology	NN
cord-321013-8pkrg0mx	346	35	Characterization	characterization	NN
cord-321013-8pkrg0mx	346	36	of	of	IN
cord-321013-8pkrg0mx	346	37	F	F	NNP
cord-321013-8pkrg0mx	346	38	-	-	HYPH
cord-321013-8pkrg0mx	346	39	actin	actin	JJ
cord-321013-8pkrg0mx	346	40	bundling	bundling	NN
cord-321013-8pkrg0mx	346	41	activity	activity	NN
cord-321013-8pkrg0mx	346	42	of	of	IN
cord-321013-8pkrg0mx	346	43	Tetrahymena	Tetrahymena	NNP
cord-321013-8pkrg0mx	346	44	elongation	elongation	NN
cord-321013-8pkrg0mx	346	45	factor	factor	NN
cord-321013-8pkrg0mx	346	46	1	1	CD
cord-321013-8pkrg0mx	346	47	alpha	alpha	NN
cord-321013-8pkrg0mx	346	48	investigated	investigate	VBN
cord-321013-8pkrg0mx	346	49	with	with	IN
cord-321013-8pkrg0mx	346	50	rabbit	rabbit	NN
cord-321013-8pkrg0mx	346	51	skeletal	skeletal	JJ
cord-321013-8pkrg0mx	346	52	muscle	muscle	NN
cord-321013-8pkrg0mx	346	53	actin	actin	NN
cord-321013-8pkrg0mx	346	54	Cytokinesis	Cytokinesis	NNP
cord-321013-8pkrg0mx	346	55	in	in	IN
cord-321013-8pkrg0mx	346	56	Tetrahymena	Tetrahymena	NNP
cord-321013-8pkrg0mx	346	57	:	:	:
cord-321013-8pkrg0mx	346	58	Determination	determination	NN
cord-321013-8pkrg0mx	346	59	of	of	IN
cord-321013-8pkrg0mx	346	60	division	division	NN
cord-321013-8pkrg0mx	346	61	plane	plane	NN
cord-321013-8pkrg0mx	346	62	and	and	CC
cord-321013-8pkrg0mx	346	63	organization	organization	NN
cord-321013-8pkrg0mx	346	64	of	of	IN
cord-321013-8pkrg0mx	346	65	contractile	contractile	NNP
cord-321013-8pkrg0mx	346	66	ring	ring	NN
cord-321013-8pkrg0mx	346	67	Detection	detection	NN
cord-321013-8pkrg0mx	346	68	of	of	IN
cord-321013-8pkrg0mx	346	69	severe	severe	JJ
cord-321013-8pkrg0mx	346	70	acute	acute	JJ
cord-321013-8pkrg0mx	346	71	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	346	72	syndrome	syndrome	NN
cord-321013-8pkrg0mx	346	73	-	-	HYPH
cord-321013-8pkrg0mx	346	74	associated	associate	VBN
cord-321013-8pkrg0mx	346	75	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	346	76	in	in	IN
cord-321013-8pkrg0mx	346	77	pneumocytes	pneumocyte	NNS
cord-321013-8pkrg0mx	346	78	of	of	IN
cord-321013-8pkrg0mx	346	79	the	the	DT
cord-321013-8pkrg0mx	346	80	lung	lung	NN
cord-321013-8pkrg0mx	346	81	Multiple	multiple	JJ
cord-321013-8pkrg0mx	346	82	organ	organ	NN
cord-321013-8pkrg0mx	346	83	infection	infection	NN
cord-321013-8pkrg0mx	346	84	and	and	CC
cord-321013-8pkrg0mx	346	85	the	the	DT
cord-321013-8pkrg0mx	346	86	pathogenesis	pathogenesis	NN
cord-321013-8pkrg0mx	346	87	of	of	IN
cord-321013-8pkrg0mx	346	88	SARS	SARS	NNP
cord-321013-8pkrg0mx	347	1	The	the	DT
cord-321013-8pkrg0mx	347	2	SARS	SARS	NNP
cord-321013-8pkrg0mx	347	3	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	347	4	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	347	5	protein	protein	NN
cord-321013-8pkrg0mx	347	6	induces	induce	VBZ
cord-321013-8pkrg0mx	347	7	actin	actin	NN
cord-321013-8pkrg0mx	347	8	reorganization	reorganization	NN
cord-321013-8pkrg0mx	347	9	and	and	CC
cord-321013-8pkrg0mx	347	10	apoptosis	apoptosis	NN
cord-321013-8pkrg0mx	347	11	in	in	IN
cord-321013-8pkrg0mx	347	12	COS-1	COS-1	NNP
cord-321013-8pkrg0mx	347	13	cells	cell	NNS
cord-321013-8pkrg0mx	347	14	in	in	IN
cord-321013-8pkrg0mx	347	15	the	the	DT
cord-321013-8pkrg0mx	347	16	absence	absence	NN
cord-321013-8pkrg0mx	347	17	of	of	IN
cord-321013-8pkrg0mx	347	18	growth	growth	NN
cord-321013-8pkrg0mx	347	19	factors	factor	NNS
cord-321013-8pkrg0mx	347	20	Protective	protective	JJ
cord-321013-8pkrg0mx	347	21	effect	effect	NN
cord-321013-8pkrg0mx	347	22	of	of	IN
cord-321013-8pkrg0mx	347	23	monoclonal	monoclonal	JJ
cord-321013-8pkrg0mx	347	24	antibodies	antibody	NNS
cord-321013-8pkrg0mx	347	25	on	on	IN
cord-321013-8pkrg0mx	347	26	lethal	lethal	JJ
cord-321013-8pkrg0mx	347	27	mouse	mouse	NN
cord-321013-8pkrg0mx	347	28	hepatitis	hepatitis	NN
cord-321013-8pkrg0mx	347	29	virus	virus	NN
cord-321013-8pkrg0mx	347	30	infection	infection	NN
cord-321013-8pkrg0mx	347	31	in	in	IN
cord-321013-8pkrg0mx	347	32	mice	mouse	NNS
cord-321013-8pkrg0mx	347	33	Inhibition	inhibition	NN
cord-321013-8pkrg0mx	347	34	of	of	IN
cord-321013-8pkrg0mx	347	35	Beta	Beta	NNP
cord-321013-8pkrg0mx	347	36	interferon	interferon	NN
cord-321013-8pkrg0mx	347	37	induction	induction	NN
cord-321013-8pkrg0mx	347	38	by	by	IN
cord-321013-8pkrg0mx	347	39	severe	severe	JJ
cord-321013-8pkrg0mx	347	40	acute	acute	JJ
cord-321013-8pkrg0mx	347	41	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	347	42	syndrome	syndrome	NN
cord-321013-8pkrg0mx	347	43	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	348	1	suggests	suggest	VBZ
cord-321013-8pkrg0mx	348	2	a	a	DT
cord-321013-8pkrg0mx	348	3	two	two	CD
cord-321013-8pkrg0mx	348	4	-	-	HYPH
cord-321013-8pkrg0mx	348	5	step	step	NN
cord-321013-8pkrg0mx	348	6	model	model	NN
cord-321013-8pkrg0mx	348	7	for	for	IN
cord-321013-8pkrg0mx	348	8	activation	activation	NN
cord-321013-8pkrg0mx	348	9	of	of	IN
cord-321013-8pkrg0mx	348	10	interferon	interferon	NN
cord-321013-8pkrg0mx	348	11	regulatory	regulatory	JJ
cord-321013-8pkrg0mx	348	12	factor	factor	NN
cord-321013-8pkrg0mx	348	13	3	3	CD
cord-321013-8pkrg0mx	348	14	Severe	severe	JJ
cord-321013-8pkrg0mx	348	15	acute	acute	JJ
cord-321013-8pkrg0mx	348	16	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	348	17	syndrome	syndrome	NN
cord-321013-8pkrg0mx	348	18	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	348	19	open	open	JJ
cord-321013-8pkrg0mx	348	20	reading	reading	NN
cord-321013-8pkrg0mx	348	21	frame	frame	NN
cord-321013-8pkrg0mx	348	22	(	(	-LRB-
cord-321013-8pkrg0mx	348	23	ORF	ORF	NNP
cord-321013-8pkrg0mx	348	24	)	)	-RRB-
cord-321013-8pkrg0mx	348	25	3b	3b	NNP
cord-321013-8pkrg0mx	348	26	,	,	,
cord-321013-8pkrg0mx	348	27	ORF	ORF	NNP
cord-321013-8pkrg0mx	348	28	6	6	CD
cord-321013-8pkrg0mx	348	29	,	,	,
cord-321013-8pkrg0mx	348	30	and	and	CC
cord-321013-8pkrg0mx	348	31	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	348	32	proteins	protein	NNS
cord-321013-8pkrg0mx	348	33	function	function	VBP
cord-321013-8pkrg0mx	348	34	as	as	IN
cord-321013-8pkrg0mx	348	35	interferon	interferon	NN
cord-321013-8pkrg0mx	348	36	antagonists	antagonist	NNS
cord-321013-8pkrg0mx	348	37	SARS	SARS	NNP
cord-321013-8pkrg0mx	348	38	-	-	HYPH
cord-321013-8pkrg0mx	348	39	CoV	CoV	NNP
cord-321013-8pkrg0mx	348	40	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	348	41	protein	protein	NN
cord-321013-8pkrg0mx	348	42	antagonizes	antagonize	VBZ
cord-321013-8pkrg0mx	348	43	IFN	IFN	NNP
cord-321013-8pkrg0mx	348	44	-	-	HYPH
cord-321013-8pkrg0mx	348	45	beta	beta	NN
cord-321013-8pkrg0mx	348	46	response	response	NN
cord-321013-8pkrg0mx	348	47	by	by	IN
cord-321013-8pkrg0mx	348	48	targeting	target	VBG
cord-321013-8pkrg0mx	348	49	initial	initial	JJ
cord-321013-8pkrg0mx	348	50	step	step	NN
cord-321013-8pkrg0mx	348	51	of	of	IN
cord-321013-8pkrg0mx	348	52	IFN	IFN	NNP
cord-321013-8pkrg0mx	348	53	-	-	HYPH
cord-321013-8pkrg0mx	348	54	beta	beta	NN
cord-321013-8pkrg0mx	348	55	induction	induction	NN
cord-321013-8pkrg0mx	348	56	pathway	pathway	NN
cord-321013-8pkrg0mx	348	57	,	,	,
cord-321013-8pkrg0mx	348	58	and	and	CC
cord-321013-8pkrg0mx	348	59	its	-PRON-	PRP$
cord-321013-8pkrg0mx	348	60	C	c	NN
cord-321013-8pkrg0mx	348	61	-	-	HYPH
cord-321013-8pkrg0mx	348	62	terminal	terminal	NN
cord-321013-8pkrg0mx	348	63	region	region	NN
cord-321013-8pkrg0mx	348	64	is	be	VBZ
cord-321013-8pkrg0mx	348	65	critical	critical	JJ
cord-321013-8pkrg0mx	348	66	for	for	IN
cord-321013-8pkrg0mx	348	67	the	the	DT
cord-321013-8pkrg0mx	348	68	antagonism	antagonism	NN
cord-321013-8pkrg0mx	348	69	Identification	identification	NN
cord-321013-8pkrg0mx	348	70	of	of	IN
cord-321013-8pkrg0mx	348	71	two	two	CD
cord-321013-8pkrg0mx	348	72	ATR	ATR	NNP
cord-321013-8pkrg0mx	348	73	-	-	HYPH
cord-321013-8pkrg0mx	348	74	dependent	dependent	JJ
cord-321013-8pkrg0mx	348	75	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	348	76	sites	site	NNS
cord-321013-8pkrg0mx	348	77	on	on	IN
cord-321013-8pkrg0mx	348	78	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	348	79	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	348	80	protein	protein	NN
cord-321013-8pkrg0mx	348	81	with	with	IN
cord-321013-8pkrg0mx	348	82	nonessential	nonessential	JJ
cord-321013-8pkrg0mx	348	83	functions	function	NNS
cord-321013-8pkrg0mx	348	84	in	in	IN
cord-321013-8pkrg0mx	348	85	viral	viral	JJ
cord-321013-8pkrg0mx	348	86	replication	replication	NN
cord-321013-8pkrg0mx	348	87	and	and	CC
cord-321013-8pkrg0mx	348	88	infectivity	infectivity	NN
cord-321013-8pkrg0mx	348	89	in	in	IN
cord-321013-8pkrg0mx	348	90	cultured	cultured	JJ
cord-321013-8pkrg0mx	348	91	cells	cell	NNS
cord-321013-8pkrg0mx	349	1	The	the	DT
cord-321013-8pkrg0mx	349	2	virion	virion	NN
cord-321013-8pkrg0mx	349	3	N	n	CD
cord-321013-8pkrg0mx	349	4	protein	protein	NN
cord-321013-8pkrg0mx	349	5	of	of	IN
cord-321013-8pkrg0mx	349	6	infectious	infectious	JJ
cord-321013-8pkrg0mx	349	7	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	349	8	virus	virus	NN
cord-321013-8pkrg0mx	349	9	is	be	VBZ
cord-321013-8pkrg0mx	349	10	more	more	RBR
cord-321013-8pkrg0mx	349	11	phosphorylated	phosphorylated	JJ
cord-321013-8pkrg0mx	349	12	than	than	IN
cord-321013-8pkrg0mx	349	13	the	the	DT
cord-321013-8pkrg0mx	349	14	N	n	CD
cord-321013-8pkrg0mx	349	15	protein	protein	NN
cord-321013-8pkrg0mx	349	16	from	from	IN
cord-321013-8pkrg0mx	349	17	infected	infected	JJ
cord-321013-8pkrg0mx	349	18	cell	cell	NN
cord-321013-8pkrg0mx	349	19	lysates	lysate	NNS
cord-321013-8pkrg0mx	349	20	Nucleocapsid	Nucleocapsid	NNP
cord-321013-8pkrg0mx	349	21	protein	protein	NN
cord-321013-8pkrg0mx	349	22	of	of	IN
cord-321013-8pkrg0mx	349	23	SARS	SARS	NNP
cord-321013-8pkrg0mx	349	24	-	-	HYPH
cord-321013-8pkrg0mx	349	25	CoV	CoV	NNP
cord-321013-8pkrg0mx	349	26	activates	activate	VBZ
cord-321013-8pkrg0mx	349	27	the	the	DT
cord-321013-8pkrg0mx	349	28	expression	expression	NN
cord-321013-8pkrg0mx	349	29	of	of	IN
cord-321013-8pkrg0mx	349	30	cyclooxygenase-2	cyclooxygenase-2	NNP
cord-321013-8pkrg0mx	349	31	by	by	IN
cord-321013-8pkrg0mx	349	32	binding	bind	VBG
cord-321013-8pkrg0mx	349	33	directly	directly	RB
cord-321013-8pkrg0mx	349	34	to	to	IN
cord-321013-8pkrg0mx	349	35	regulatory	regulatory	JJ
cord-321013-8pkrg0mx	349	36	elements	element	NNS
cord-321013-8pkrg0mx	349	37	for	for	IN
cord-321013-8pkrg0mx	349	38	nuclear	nuclear	JJ
cord-321013-8pkrg0mx	349	39	factor	factor	NN
cord-321013-8pkrg0mx	349	40	-	-	HYPH
cord-321013-8pkrg0mx	349	41	kappa	kappa	NN
cord-321013-8pkrg0mx	349	42	B	B	NNP
cord-321013-8pkrg0mx	349	43	and	and	CC
cord-321013-8pkrg0mx	349	44	CCAAT	CCAAT	NNP
cord-321013-8pkrg0mx	349	45	/	/	SYM
cord-321013-8pkrg0mx	349	46	enhancer	enhancer	NN
cord-321013-8pkrg0mx	349	47	binding	bind	VBG
cord-321013-8pkrg0mx	349	48	protein	protein	NN
cord-321013-8pkrg0mx	349	49	Activation	Activation	NNP
cord-321013-8pkrg0mx	349	50	of	of	IN
cord-321013-8pkrg0mx	349	51	AP-1	AP-1	NNP
cord-321013-8pkrg0mx	349	52	signal	signal	NN
cord-321013-8pkrg0mx	349	53	transduction	transduction	NN
cord-321013-8pkrg0mx	349	54	pathway	pathway	NN
cord-321013-8pkrg0mx	349	55	by	by	IN
cord-321013-8pkrg0mx	349	56	SARS	SARS	NNP
cord-321013-8pkrg0mx	349	57	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	349	58	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	349	59	protein	protein	NN
cord-321013-8pkrg0mx	349	60	Characterisation	Characterisation	NNP
cord-321013-8pkrg0mx	349	61	of	of	IN
cord-321013-8pkrg0mx	349	62	human	human	JJ
cord-321013-8pkrg0mx	349	63	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	349	64	-	-	:
cord-321013-8pkrg0mx	349	65	NL63	NL63	NNP
cord-321013-8pkrg0mx	349	66	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	349	67	protein	protein	NN
cord-321013-8pkrg0mx	350	1	The	the	DT
cord-321013-8pkrg0mx	350	2	SARS	SARS	NNP
cord-321013-8pkrg0mx	350	3	-	-	HYPH
cord-321013-8pkrg0mx	350	4	CoV	CoV	NNP
cord-321013-8pkrg0mx	350	5	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	350	6	protein	protein	NNP
cord-321013-8pkrg0mx	350	7	:	:	:
cord-321013-8pkrg0mx	350	8	A	a	DT
cord-321013-8pkrg0mx	350	9	protein	protein	NN
cord-321013-8pkrg0mx	350	10	with	with	IN
cord-321013-8pkrg0mx	350	11	multifarious	multifarious	JJ
cord-321013-8pkrg0mx	350	12	activities	activity	NNS
cord-321013-8pkrg0mx	350	13	Background	Background	NNP
cord-321013-8pkrg0mx	350	14	paper	paper	NN
cord-321013-8pkrg0mx	350	15	.	.	.
cord-321013-8pkrg0mx	351	1	Functions	function	NNS
cord-321013-8pkrg0mx	351	2	of	of	IN
cord-321013-8pkrg0mx	351	3	the	the	DT
cord-321013-8pkrg0mx	351	4	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	351	5	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	351	6	protein	protein	NN
cord-321013-8pkrg0mx	351	7	Protein	Protein	NNP
cord-321013-8pkrg0mx	351	8	interactions	interaction	NNS
cord-321013-8pkrg0mx	351	9	during	during	IN
cord-321013-8pkrg0mx	351	10	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	351	11	assembly	assembly	NN
cord-321013-8pkrg0mx	351	12	Envelope	Envelope	NNP
cord-321013-8pkrg0mx	351	13	glycoprotein	glycoprotein	NN
cord-321013-8pkrg0mx	351	14	interactions	interaction	NNS
cord-321013-8pkrg0mx	351	15	in	in	IN
cord-321013-8pkrg0mx	351	16	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	351	17	assembly	assembly	NN
cord-321013-8pkrg0mx	351	18	Discovery	Discovery	NNP
cord-321013-8pkrg0mx	351	19	of	of	IN
cord-321013-8pkrg0mx	351	20	host	host	NN
cord-321013-8pkrg0mx	351	21	-	-	HYPH
cord-321013-8pkrg0mx	351	22	viral	viral	JJ
cord-321013-8pkrg0mx	351	23	protein	protein	NN
cord-321013-8pkrg0mx	351	24	complexes	complex	NNS
cord-321013-8pkrg0mx	351	25	during	during	IN
cord-321013-8pkrg0mx	351	26	infection	infection	NN
cord-321013-8pkrg0mx	351	27	Nucleocapsid	Nucleocapsid	NNP
cord-321013-8pkrg0mx	351	28	protein	protein	NN
cord-321013-8pkrg0mx	351	29	of	of	IN
cord-321013-8pkrg0mx	351	30	SARS	SARS	NNP
cord-321013-8pkrg0mx	351	31	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	351	32	tightly	tightly	RB
cord-321013-8pkrg0mx	351	33	binds	bind	VBZ
cord-321013-8pkrg0mx	351	34	to	to	IN
cord-321013-8pkrg0mx	351	35	human	human	JJ
cord-321013-8pkrg0mx	351	36	cyclophilin	cyclophilin	NN
cord-321013-8pkrg0mx	352	1	A	a	DT
cord-321013-8pkrg0mx	352	2	Interactions	Interactions	NNPS
cord-321013-8pkrg0mx	352	3	of	of	IN
cord-321013-8pkrg0mx	352	4	SARS	SARS	NNP
cord-321013-8pkrg0mx	352	5	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	352	6	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	352	7	protein	protein	NN
cord-321013-8pkrg0mx	352	8	with	with	IN
cord-321013-8pkrg0mx	352	9	the	the	DT
cord-321013-8pkrg0mx	352	10	host	host	NN
cord-321013-8pkrg0mx	352	11	cell	cell	NN
cord-321013-8pkrg0mx	352	12	proteasome	proteasome	NN
cord-321013-8pkrg0mx	352	13	subunit	subunit	NN
cord-321013-8pkrg0mx	352	14	p42	p42	CD
cord-321013-8pkrg0mx	352	15	Co	co	NN
cord-321013-8pkrg0mx	352	16	-	-	NN
cord-321013-8pkrg0mx	352	17	localization	localization	NN
cord-321013-8pkrg0mx	352	18	analysis	analysis	NN
cord-321013-8pkrg0mx	352	19	between	between	IN
cord-321013-8pkrg0mx	352	20	porcine	porcine	JJ
cord-321013-8pkrg0mx	352	21	epidemic	epidemic	NN
cord-321013-8pkrg0mx	352	22	diarrhea	diarrhea	NN
cord-321013-8pkrg0mx	352	23	virus	virus	NN
cord-321013-8pkrg0mx	352	24	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	352	25	protein	protein	NN
cord-321013-8pkrg0mx	352	26	and	and	CC
cord-321013-8pkrg0mx	352	27	nucleolar	nucleolar	NNP
cord-321013-8pkrg0mx	352	28	phosphoprotein	phosphoprotein	NNP
cord-321013-8pkrg0mx	352	29	B23.1	B23.1	NNP
cord-321013-8pkrg0mx	352	30	.	.	.
cord-321013-8pkrg0mx	353	1	Wei	Wei	NNP
cord-321013-8pkrg0mx	353	2	Sheng	Sheng	NNP
cord-321013-8pkrg0mx	353	3	Wu	Wu	NNP
cord-321013-8pkrg0mx	353	4	Xue	Xue	NNP
cord-321013-8pkrg0mx	353	5	Bao	Bao	NNP
cord-321013-8pkrg0mx	354	1	The	the	DT
cord-321013-8pkrg0mx	354	2	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	354	3	protein	protein	NN
cord-321013-8pkrg0mx	354	4	of	of	IN
cord-321013-8pkrg0mx	354	5	SARS	SARS	NNP
cord-321013-8pkrg0mx	354	6	-	-	HYPH
cord-321013-8pkrg0mx	354	7	associated	associate	VBN
cord-321013-8pkrg0mx	354	8	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	354	9	inhibits	inhibit	VBZ
cord-321013-8pkrg0mx	354	10	B23	B23	NNP
cord-321013-8pkrg0mx	354	11	phosphorylation	phosphorylation	NN
cord-321013-8pkrg0mx	354	12	Severe	severe	JJ
cord-321013-8pkrg0mx	354	13	acute	acute	JJ
cord-321013-8pkrg0mx	354	14	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	354	15	syndrome	syndrome	NN
cord-321013-8pkrg0mx	354	16	-	-	HYPH
cord-321013-8pkrg0mx	354	17	associated	associate	VBN
cord-321013-8pkrg0mx	354	18	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	354	19	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	354	20	protein	protein	NN
cord-321013-8pkrg0mx	354	21	interacts	interact	VBZ
cord-321013-8pkrg0mx	354	22	with	with	IN
cord-321013-8pkrg0mx	354	23	Smad3	Smad3	NNP
cord-321013-8pkrg0mx	354	24	and	and	CC
cord-321013-8pkrg0mx	354	25	modulates	modulate	VBZ
cord-321013-8pkrg0mx	354	26	transforming	transform	VBG
cord-321013-8pkrg0mx	354	27	growth	growth	NN
cord-321013-8pkrg0mx	354	28	factor	factor	NN
cord-321013-8pkrg0mx	355	1	-beta	-beta	VBG
cord-321013-8pkrg0mx	355	2	signaling	signal	VBG
cord-321013-8pkrg0mx	355	3	Cxcl16	Cxcl16	NNP
cord-321013-8pkrg0mx	355	4	interact	interact	VBP
cord-321013-8pkrg0mx	355	5	with	with	IN
cord-321013-8pkrg0mx	355	6	SARS	SARS	NNP
cord-321013-8pkrg0mx	355	7	-	-	HYPH
cord-321013-8pkrg0mx	355	8	CoV	CoV	NNP
cord-321013-8pkrg0mx	355	9	N	n	CD
cord-321013-8pkrg0mx	355	10	protein	protein	NN
cord-321013-8pkrg0mx	355	11	in	in	IN
cord-321013-8pkrg0mx	355	12	and	and	CC
cord-321013-8pkrg0mx	355	13	out	out	RB
cord-321013-8pkrg0mx	356	1	cell	cell	NN
cord-321013-8pkrg0mx	356	2	SARS	SARS	NNP
cord-321013-8pkrg0mx	356	3	-	-	HYPH
cord-321013-8pkrg0mx	356	4	CoV	CoV	NNP
cord-321013-8pkrg0mx	356	5	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	356	6	protein	protein	NNP
cord-321013-8pkrg0mx	356	7	interacts	interact	VBZ
cord-321013-8pkrg0mx	356	8	with	with	IN
cord-321013-8pkrg0mx	356	9	cellular	cellular	JJ
cord-321013-8pkrg0mx	356	10	pyruvate	pyruvate	NN
cord-321013-8pkrg0mx	356	11	kinase	kinase	NN
cord-321013-8pkrg0mx	356	12	protein	protein	NN
cord-321013-8pkrg0mx	356	13	and	and	CC
cord-321013-8pkrg0mx	356	14	inhibits	inhibit	VBZ
cord-321013-8pkrg0mx	356	15	its	-PRON-	PRP$
cord-321013-8pkrg0mx	356	16	activity	activity	NN
cord-321013-8pkrg0mx	357	1	The	the	DT
cord-321013-8pkrg0mx	357	2	cellular	cellular	JJ
cord-321013-8pkrg0mx	357	3	interactome	interactome	NN
cord-321013-8pkrg0mx	357	4	of	of	IN
cord-321013-8pkrg0mx	357	5	the	the	DT
cord-321013-8pkrg0mx	357	6	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	357	7	infectious	infectious	JJ
cord-321013-8pkrg0mx	357	8	bronchitis	bronchitis	NN
cord-321013-8pkrg0mx	357	9	virus	virus	NN
cord-321013-8pkrg0mx	357	10	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	357	11	protein	protein	NN
cord-321013-8pkrg0mx	357	12	and	and	CC
cord-321013-8pkrg0mx	357	13	functional	functional	JJ
cord-321013-8pkrg0mx	357	14	implications	implication	NNS
cord-321013-8pkrg0mx	357	15	for	for	IN
cord-321013-8pkrg0mx	357	16	virus	virus	NN
cord-321013-8pkrg0mx	357	17	biology	biology	NN
cord-321013-8pkrg0mx	357	18	Viruses	virus	NNS
cord-321013-8pkrg0mx	357	19	and	and	CC
cord-321013-8pkrg0mx	357	20	interactomes	interactomes	NNPS
cord-321013-8pkrg0mx	357	21	in	in	IN
cord-321013-8pkrg0mx	357	22	translation	translation	NN
cord-321013-8pkrg0mx	357	23	Antibody	Antibody	NNP
cord-321013-8pkrg0mx	357	24	response	response	NN
cord-321013-8pkrg0mx	357	25	of	of	IN
cord-321013-8pkrg0mx	357	26	patients	patient	NNS
cord-321013-8pkrg0mx	357	27	with	with	IN
cord-321013-8pkrg0mx	357	28	severe	severe	JJ
cord-321013-8pkrg0mx	357	29	acute	acute	JJ
cord-321013-8pkrg0mx	357	30	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	357	31	syndrome	syndrome	NN
cord-321013-8pkrg0mx	357	32	(	(	-LRB-
cord-321013-8pkrg0mx	357	33	SARS	SARS	NNP
cord-321013-8pkrg0mx	357	34	)	)	-RRB-
cord-321013-8pkrg0mx	357	35	targets	target	VBZ
cord-321013-8pkrg0mx	357	36	the	the	DT
cord-321013-8pkrg0mx	357	37	viral	viral	JJ
cord-321013-8pkrg0mx	357	38	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	357	39	Generation	generation	NN
cord-321013-8pkrg0mx	357	40	and	and	CC
cord-321013-8pkrg0mx	357	41	characterization	characterization	NN
cord-321013-8pkrg0mx	357	42	of	of	IN
cord-321013-8pkrg0mx	357	43	DNA	dna	NN
cord-321013-8pkrg0mx	357	44	vaccines	vaccine	NNS
cord-321013-8pkrg0mx	357	45	targeting	target	VBG
cord-321013-8pkrg0mx	357	46	the	the	DT
cord-321013-8pkrg0mx	357	47	nucleocapsid	nucleocapsid	NNP
cord-321013-8pkrg0mx	357	48	protein	protein	NN
cord-321013-8pkrg0mx	357	49	of	of	IN
cord-321013-8pkrg0mx	357	50	severe	severe	JJ
cord-321013-8pkrg0mx	357	51	acute	acute	JJ
cord-321013-8pkrg0mx	357	52	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	357	53	syndrome	syndrome	NN
cord-321013-8pkrg0mx	357	54	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	357	55	Contributions	contribution	NNS
cord-321013-8pkrg0mx	357	56	of	of	IN
cord-321013-8pkrg0mx	357	57	the	the	DT
cord-321013-8pkrg0mx	357	58	structural	structural	JJ
cord-321013-8pkrg0mx	357	59	proteins	protein	NNS
cord-321013-8pkrg0mx	357	60	of	of	IN
cord-321013-8pkrg0mx	357	61	severe	severe	JJ
cord-321013-8pkrg0mx	357	62	acute	acute	JJ
cord-321013-8pkrg0mx	357	63	respiratory	respiratory	JJ
cord-321013-8pkrg0mx	357	64	syndrome	syndrome	NN
cord-321013-8pkrg0mx	357	65	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	357	66	to	to	IN
cord-321013-8pkrg0mx	357	67	protective	protective	JJ
cord-321013-8pkrg0mx	357	68	immunity	immunity	NN
cord-321013-8pkrg0mx	357	69	Immunoreactivity	Immunoreactivity	NNP
cord-321013-8pkrg0mx	357	70	characterisation	characterisation	NN
cord-321013-8pkrg0mx	357	71	of	of	IN
cord-321013-8pkrg0mx	357	72	the	the	DT
cord-321013-8pkrg0mx	357	73	three	three	CD
cord-321013-8pkrg0mx	357	74	structural	structural	JJ
cord-321013-8pkrg0mx	357	75	regions	region	NNS
cord-321013-8pkrg0mx	357	76	of	of	IN
cord-321013-8pkrg0mx	357	77	the	the	DT
cord-321013-8pkrg0mx	357	78	human	human	JJ
cord-321013-8pkrg0mx	357	79	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	357	80	OC43	OC43	NNP
cord-321013-8pkrg0mx	357	81	nucleocapsid	nucleocapsid	NN
cord-321013-8pkrg0mx	357	82	protein	protein	NN
cord-321013-8pkrg0mx	357	83	by	by	IN
cord-321013-8pkrg0mx	357	84	Western	western	JJ
cord-321013-8pkrg0mx	357	85	blot	blot	NN
cord-321013-8pkrg0mx	357	86	:	:	:
cord-321013-8pkrg0mx	358	1	Implications	implication	NNS
cord-321013-8pkrg0mx	358	2	for	for	IN
cord-321013-8pkrg0mx	358	3	the	the	DT
cord-321013-8pkrg0mx	358	4	diagnosis	diagnosis	NN
cord-321013-8pkrg0mx	358	5	of	of	IN
cord-321013-8pkrg0mx	358	6	coronavirus	coronavirus	NN
cord-321013-8pkrg0mx	358	7	infection	infection	NN
cord-321013-8pkrg0mx	358	8	Burtram	Burtram	NNP
cord-321013-8pkrg0mx	358	9	C.	C.	NNP
cord-321013-8pkrg0mx	358	10	Fielding	Fielding	NNP
cord-321013-8pkrg0mx	358	11	receives	receive	VBZ
cord-321013-8pkrg0mx	358	12	funding	funding	NN
cord-321013-8pkrg0mx	358	13	from	from	IN
cord-321013-8pkrg0mx	358	14	the	the	DT
cord-321013-8pkrg0mx	358	15	Senate	Senate	NNP
cord-321013-8pkrg0mx	358	16	Research	Research	NNP
cord-321013-8pkrg0mx	358	17	Fund	Fund	NNP
cord-321013-8pkrg0mx	358	18	,	,	,
cord-321013-8pkrg0mx	358	19	University	University	NNP
cord-321013-8pkrg0mx	358	20	of	of	IN
cord-321013-8pkrg0mx	358	21	the	the	DT
cord-321013-8pkrg0mx	358	22	Western	Western	NNP
cord-321013-8pkrg0mx	358	23	Cape	Cape	NNP
cord-321013-8pkrg0mx	358	24	and	and	CC
cord-321013-8pkrg0mx	358	25	the	the	DT
cord-321013-8pkrg0mx	358	26	National	National	NNP
cord-321013-8pkrg0mx	358	27	Research	Research	NNP
cord-321013-8pkrg0mx	358	28	Foundation	Foundation	NNP
cord-321013-8pkrg0mx	358	29	,	,	,
cord-321013-8pkrg0mx	358	30	South	South	NNP
cord-321013-8pkrg0mx	358	31	Africa	Africa	NNP
cord-321013-8pkrg0mx	358	32	.	.	.
cord-321013-8pkrg0mx	359	1	Any	any	DT
cord-321013-8pkrg0mx	359	2	opinion	opinion	NN
cord-321013-8pkrg0mx	359	3	,	,	,
cord-321013-8pkrg0mx	359	4	findings	finding	NNS
cord-321013-8pkrg0mx	359	5	and	and	CC
cord-321013-8pkrg0mx	359	6	conclusions	conclusion	NNS
cord-321013-8pkrg0mx	359	7	or	or	CC
cord-321013-8pkrg0mx	359	8	recommendations	recommendation	NNS
cord-321013-8pkrg0mx	359	9	expressed	express	VBN
cord-321013-8pkrg0mx	359	10	in	in	IN
cord-321013-8pkrg0mx	359	11	this	this	DT
cord-321013-8pkrg0mx	359	12	material	material	NN
cord-321013-8pkrg0mx	359	13	are	be	VBP
cord-321013-8pkrg0mx	359	14	those	those	DT
cord-321013-8pkrg0mx	359	15	of	of	IN
cord-321013-8pkrg0mx	359	16	the	the	DT
cord-321013-8pkrg0mx	359	17	author	author	NN
cord-321013-8pkrg0mx	359	18	and	and	CC
cord-321013-8pkrg0mx	359	19	therefore	therefore	RB
cord-321013-8pkrg0mx	359	20	the	the	DT
cord-321013-8pkrg0mx	359	21	NRF	NRF	NNP
cord-321013-8pkrg0mx	359	22	does	do	VBZ
cord-321013-8pkrg0mx	359	23	not	not	RB
cord-321013-8pkrg0mx	359	24	accept	accept	VB
cord-321013-8pkrg0mx	359	25	any	any	DT
cord-321013-8pkrg0mx	359	26	liability	liability	NN
cord-321013-8pkrg0mx	359	27	in	in	IN
cord-321013-8pkrg0mx	359	28	regard	regard	NN
cord-321013-8pkrg0mx	359	29	thereto	thereto	RB
cord-321013-8pkrg0mx	359	30	.	.	.
cord-321013-8pkrg0mx	360	1	The	the	DT
cord-321013-8pkrg0mx	360	2	authors	author	NNS
cord-321013-8pkrg0mx	360	3	apologize	apologize	VBP
cord-321013-8pkrg0mx	360	4	to	to	IN
cord-321013-8pkrg0mx	360	5	any	any	DT
cord-321013-8pkrg0mx	360	6	author	author	NN
cord-321013-8pkrg0mx	360	7	whose	whose	WP$
cord-321013-8pkrg0mx	360	8	work	work	NN
cord-321013-8pkrg0mx	360	9	was	be	VBD
cord-321013-8pkrg0mx	360	10	inadvertently	inadvertently	RB
cord-321013-8pkrg0mx	360	11	omitted	omit	VBN
cord-321013-8pkrg0mx	360	12	from	from	IN
cord-321013-8pkrg0mx	360	13	this	this	DT
cord-321013-8pkrg0mx	360	14	review	review	NN
cord-321013-8pkrg0mx	360	15	.	.	.
cord-321013-8pkrg0mx	361	1	The	the	DT
cord-321013-8pkrg0mx	361	2	authors	author	NNS
cord-321013-8pkrg0mx	361	3	declare	declare	VBP
cord-321013-8pkrg0mx	361	4	no	no	DT
cord-321013-8pkrg0mx	361	5	conflict	conflict	NN
cord-321013-8pkrg0mx	361	6	of	of	IN
cord-321013-8pkrg0mx	361	7	interest	interest	NN
cord-321013-8pkrg0mx	361	8	.	.	.