id	sid	tid	token	lemma	pos
cord-313312-h607itv2	1	1	key	key	NN
cord-313312-h607itv2	1	2	:	:	:
cord-313312-h607itv2	2	1	cord-313312-h607itv2	cord-313312-h607itv2	NN
cord-313312-h607itv2	2	2	authors	author	NNS
cord-313312-h607itv2	2	3	:	:	:
cord-313312-h607itv2	2	4	Mok	Mok	NNP
cord-313312-h607itv2	2	5	,	,	,
cord-313312-h607itv2	2	6	Darren	Darren	NNP
cord-313312-h607itv2	2	7	Z.	Z.	NNP
cord-313312-h607itv2	2	8	L.	L.	NNP
cord-313312-h607itv2	2	9	;	;	:
cord-313312-h607itv2	2	10	Chan	Chan	NNP
cord-313312-h607itv2	2	11	,	,	,
cord-313312-h607itv2	2	12	Kuan	Kuan	NNP
cord-313312-h607itv2	2	13	Rong	Rong	NNP
cord-313312-h607itv2	3	1	title	title	NN
cord-313312-h607itv2	3	2	:	:	:
cord-313312-h607itv2	4	1	The	the	DT
cord-313312-h607itv2	4	2	Effects	effect	NNS
cord-313312-h607itv2	4	3	of	of	IN
cord-313312-h607itv2	4	4	Pre	pre	JJ
cord-313312-h607itv2	4	5	-	-	JJ
cord-313312-h607itv2	4	6	Existing	existing	JJ
cord-313312-h607itv2	4	7	Antibodies	Antibodies	NNPS
cord-313312-h607itv2	4	8	on	on	IN
cord-313312-h607itv2	4	9	Live	live	JJ
cord-313312-h607itv2	4	10	-	-	HYPH
cord-313312-h607itv2	4	11	Attenuated	attenuate	VBN
cord-313312-h607itv2	4	12	Viral	Viral	NNP
cord-313312-h607itv2	4	13	Vaccines	Vaccines	NNPS
cord-313312-h607itv2	4	14	date	date	NN
cord-313312-h607itv2	4	15	:	:	:
cord-313312-h607itv2	4	16	2020	2020	CD
cord-313312-h607itv2	4	17	-	-	HYPH
cord-313312-h607itv2	4	18	05	05	CD
cord-313312-h607itv2	4	19	-	-	HYPH
cord-313312-h607itv2	4	20	08	08	CD
cord-313312-h607itv2	4	21	journal	journal	NN
cord-313312-h607itv2	4	22	:	:	:
cord-313312-h607itv2	5	1	Viruses	virus	NNS
cord-313312-h607itv2	5	2	DOI	DOI	NNP
cord-313312-h607itv2	5	3	:	:	:
cord-313312-h607itv2	6	1	10.3390	10.3390	CD
cord-313312-h607itv2	7	1	/v12050520	/v12050520	.
cord-313312-h607itv2	8	1	sha	sha	NNP
cord-313312-h607itv2	8	2	:	:	:
cord-313312-h607itv2	8	3	8d12199734c818c025cda267be5fe8fe0d6641cd	8d12199734c818c025cda267be5fe8fe0d6641cd	NNP
cord-313312-h607itv2	8	4	doc_id	doc_id	CD
cord-313312-h607itv2	8	5	:	:	:
cord-313312-h607itv2	9	1	313312	313312	CD
cord-313312-h607itv2	9	2	cord_uid	cord_uid	NN
cord-313312-h607itv2	9	3	:	:	:
cord-313312-h607itv2	10	1	h607itv2	h607itv2	NNP
cord-313312-h607itv2	10	2	Live	live	RB
cord-313312-h607itv2	10	3	-	-	HYPH
cord-313312-h607itv2	10	4	attenuated	attenuate	VBN
cord-313312-h607itv2	10	5	vaccines	vaccine	NNS
cord-313312-h607itv2	10	6	(	(	-LRB-
cord-313312-h607itv2	10	7	LAVs	lav	NNS
cord-313312-h607itv2	10	8	)	)	-RRB-
cord-313312-h607itv2	10	9	have	have	VBP
cord-313312-h607itv2	10	10	achieved	achieve	VBN
cord-313312-h607itv2	10	11	remarkable	remarkable	JJ
cord-313312-h607itv2	10	12	successes	success	NNS
cord-313312-h607itv2	10	13	in	in	IN
cord-313312-h607itv2	10	14	controlling	control	VBG
cord-313312-h607itv2	10	15	virus	virus	NN
cord-313312-h607itv2	10	16	spread	spread	NN
cord-313312-h607itv2	10	17	,	,	,
cord-313312-h607itv2	10	18	as	as	RB
cord-313312-h607itv2	10	19	well	well	RB
cord-313312-h607itv2	10	20	as	as	IN
cord-313312-h607itv2	10	21	for	for	IN
cord-313312-h607itv2	10	22	other	other	JJ
cord-313312-h607itv2	10	23	applications	application	NNS
cord-313312-h607itv2	10	24	such	such	JJ
cord-313312-h607itv2	10	25	as	as	IN
cord-313312-h607itv2	10	26	cancer	cancer	NN
cord-313312-h607itv2	10	27	immunotherapy	immunotherapy	NN
cord-313312-h607itv2	10	28	.	.	.
cord-313312-h607itv2	11	1	However	however	RB
cord-313312-h607itv2	11	2	,	,	,
cord-313312-h607itv2	11	3	with	with	IN
cord-313312-h607itv2	11	4	rapid	rapid	JJ
cord-313312-h607itv2	11	5	increases	increase	NNS
cord-313312-h607itv2	11	6	in	in	IN
cord-313312-h607itv2	11	7	international	international	JJ
cord-313312-h607itv2	11	8	travel	travel	NN
cord-313312-h607itv2	11	9	,	,	,
cord-313312-h607itv2	11	10	globalization	globalization	NN
cord-313312-h607itv2	11	11	,	,	,
cord-313312-h607itv2	11	12	geographic	geographic	JJ
cord-313312-h607itv2	11	13	spread	spread	NN
cord-313312-h607itv2	11	14	of	of	IN
cord-313312-h607itv2	11	15	viral	viral	JJ
cord-313312-h607itv2	11	16	vectors	vector	NNS
cord-313312-h607itv2	11	17	,	,	,
cord-313312-h607itv2	11	18	and	and	CC
cord-313312-h607itv2	11	19	widespread	widespread	JJ
cord-313312-h607itv2	11	20	use	use	NN
cord-313312-h607itv2	11	21	of	of	IN
cord-313312-h607itv2	11	22	vaccines	vaccine	NNS
cord-313312-h607itv2	11	23	,	,	,
cord-313312-h607itv2	11	24	there	there	EX
cord-313312-h607itv2	11	25	is	be	VBZ
cord-313312-h607itv2	11	26	an	an	DT
cord-313312-h607itv2	11	27	increasing	increase	VBG
cord-313312-h607itv2	11	28	need	need	NN
cord-313312-h607itv2	11	29	to	to	TO
cord-313312-h607itv2	11	30	consider	consider	VB
cord-313312-h607itv2	11	31	how	how	WRB
cord-313312-h607itv2	11	32	pre	pre	JJ
cord-313312-h607itv2	11	33	-	-	NN
cord-313312-h607itv2	11	34	exposure	exposure	NN
cord-313312-h607itv2	11	35	to	to	IN
cord-313312-h607itv2	11	36	viruses	virus	NNS
cord-313312-h607itv2	11	37	which	which	WDT
cord-313312-h607itv2	11	38	share	share	VBP
cord-313312-h607itv2	11	39	similar	similar	JJ
cord-313312-h607itv2	11	40	antigenic	antigenic	JJ
cord-313312-h607itv2	11	41	regions	region	NNS
cord-313312-h607itv2	11	42	can	can	MD
cord-313312-h607itv2	11	43	impact	impact	VB
cord-313312-h607itv2	11	44	vaccine	vaccine	NN
cord-313312-h607itv2	11	45	efficacy	efficacy	NN
cord-313312-h607itv2	11	46	.	.	.
cord-313312-h607itv2	12	1	Pre	pre	JJ
cord-313312-h607itv2	12	2	-	-	JJ
cord-313312-h607itv2	12	3	existing	existing	JJ
cord-313312-h607itv2	12	4	antibodies	antibody	NNS
cord-313312-h607itv2	12	5	,	,	,
cord-313312-h607itv2	12	6	derived	derive	VBN
cord-313312-h607itv2	12	7	from	from	IN
cord-313312-h607itv2	12	8	either	either	CC
cord-313312-h607itv2	12	9	from	from	IN
cord-313312-h607itv2	12	10	maternal	maternal	JJ
cord-313312-h607itv2	12	11	–	–	:
cord-313312-h607itv2	12	12	fetal	fetal	JJ
cord-313312-h607itv2	12	13	transmission	transmission	NN
cord-313312-h607itv2	12	14	,	,	,
cord-313312-h607itv2	12	15	or	or	CC
cord-313312-h607itv2	12	16	by	by	IN
cord-313312-h607itv2	12	17	previous	previous	JJ
cord-313312-h607itv2	12	18	infection	infection	NN
cord-313312-h607itv2	12	19	or	or	CC
cord-313312-h607itv2	12	20	vaccination	vaccination	NN
cord-313312-h607itv2	12	21	,	,	,
cord-313312-h607itv2	12	22	have	have	VBP
cord-313312-h607itv2	12	23	been	be	VBN
cord-313312-h607itv2	12	24	demonstrated	demonstrate	VBN
cord-313312-h607itv2	12	25	to	to	TO
cord-313312-h607itv2	12	26	interfere	interfere	VB
cord-313312-h607itv2	12	27	with	with	IN
cord-313312-h607itv2	12	28	vaccine	vaccine	NN
cord-313312-h607itv2	12	29	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	12	30	of	of	IN
cord-313312-h607itv2	12	31	measles	measle	NNS
cord-313312-h607itv2	12	32	,	,	,
cord-313312-h607itv2	12	33	adenovirus	adenovirus	NN
cord-313312-h607itv2	12	34	,	,	,
cord-313312-h607itv2	12	35	and	and	CC
cord-313312-h607itv2	12	36	influenza	influenza	NN
cord-313312-h607itv2	12	37	LAVs	lav	NNS
cord-313312-h607itv2	12	38	.	.	.
cord-313312-h607itv2	13	1	Immune	immune	JJ
cord-313312-h607itv2	13	2	interference	interference	NN
cord-313312-h607itv2	13	3	of	of	IN
cord-313312-h607itv2	13	4	LAVs	lav	NNS
cord-313312-h607itv2	13	5	can	can	MD
cord-313312-h607itv2	13	6	be	be	VB
cord-313312-h607itv2	13	7	caused	cause	VBN
cord-313312-h607itv2	13	8	by	by	IN
cord-313312-h607itv2	13	9	the	the	DT
cord-313312-h607itv2	13	10	formation	formation	NN
cord-313312-h607itv2	13	11	of	of	IN
cord-313312-h607itv2	13	12	virus	virus	NN
cord-313312-h607itv2	13	13	–	–	:
cord-313312-h607itv2	13	14	antibody	antibody	NN
cord-313312-h607itv2	13	15	complexes	complex	NNS
cord-313312-h607itv2	13	16	that	that	WDT
cord-313312-h607itv2	13	17	neutralize	neutralize	VBP
cord-313312-h607itv2	13	18	virus	virus	NN
cord-313312-h607itv2	13	19	infection	infection	NN
cord-313312-h607itv2	13	20	in	in	IN
cord-313312-h607itv2	13	21	antigen	antigen	NN
cord-313312-h607itv2	13	22	-	-	HYPH
cord-313312-h607itv2	13	23	presenting	present	VBG
cord-313312-h607itv2	13	24	cells	cell	NNS
cord-313312-h607itv2	13	25	,	,	,
cord-313312-h607itv2	13	26	or	or	CC
cord-313312-h607itv2	13	27	by	by	IN
cord-313312-h607itv2	13	28	the	the	DT
cord-313312-h607itv2	13	29	cross	cross	NN
cord-313312-h607itv2	13	30	-	-	NN
cord-313312-h607itv2	13	31	linking	linking	NN
cord-313312-h607itv2	13	32	of	of	IN
cord-313312-h607itv2	13	33	the	the	DT
cord-313312-h607itv2	13	34	B	b	NN
cord-313312-h607itv2	13	35	-	-	HYPH
cord-313312-h607itv2	13	36	cell	cell	NN
cord-313312-h607itv2	13	37	receptor	receptor	NN
cord-313312-h607itv2	13	38	with	with	IN
cord-313312-h607itv2	13	39	the	the	DT
cord-313312-h607itv2	13	40	inhibitory	inhibitory	JJ
cord-313312-h607itv2	13	41	receptor	receptor	NN
cord-313312-h607itv2	13	42	,	,	,
cord-313312-h607itv2	13	43	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	13	44	.	.	.
cord-313312-h607itv2	14	1	On	on	IN
cord-313312-h607itv2	14	2	the	the	DT
cord-313312-h607itv2	14	3	other	other	JJ
cord-313312-h607itv2	14	4	hand	hand	NN
cord-313312-h607itv2	14	5	,	,	,
cord-313312-h607itv2	14	6	pre	pre	VB
cord-313312-h607itv2	14	7	-	-	JJ
cord-313312-h607itv2	14	8	existing	existing	JJ
cord-313312-h607itv2	14	9	antibodies	antibody	NNS
cord-313312-h607itv2	14	10	can	can	MD
cord-313312-h607itv2	14	11	augment	augment	VB
cord-313312-h607itv2	14	12	flaviviral	flaviviral	NNP
cord-313312-h607itv2	14	13	LAV	LAV	NNP
cord-313312-h607itv2	14	14	efficacy	efficacy	NN
cord-313312-h607itv2	14	15	such	such	JJ
cord-313312-h607itv2	14	16	as	as	IN
cord-313312-h607itv2	14	17	that	that	DT
cord-313312-h607itv2	14	18	of	of	IN
cord-313312-h607itv2	14	19	dengue	dengue	NN
cord-313312-h607itv2	14	20	and	and	CC
cord-313312-h607itv2	14	21	yellow	yellow	JJ
cord-313312-h607itv2	14	22	fever	fever	NN
cord-313312-h607itv2	14	23	virus	virus	NN
cord-313312-h607itv2	14	24	,	,	,
cord-313312-h607itv2	14	25	especially	especially	RB
cord-313312-h607itv2	14	26	when	when	WRB
cord-313312-h607itv2	14	27	pre	pre	JJ
cord-313312-h607itv2	14	28	-	-	JJ
cord-313312-h607itv2	14	29	existing	existing	JJ
cord-313312-h607itv2	14	30	antibodies	antibody	NNS
cord-313312-h607itv2	14	31	are	be	VBP
cord-313312-h607itv2	14	32	present	present	JJ
cord-313312-h607itv2	14	33	at	at	IN
cord-313312-h607itv2	14	34	sub	sub	NN
cord-313312-h607itv2	14	35	-	-	JJ
cord-313312-h607itv2	14	36	neutralizing	neutralize	VBG
cord-313312-h607itv2	14	37	levels	level	NNS
cord-313312-h607itv2	14	38	.	.	.
cord-313312-h607itv2	15	1	The	the	DT
cord-313312-h607itv2	15	2	increased	increased	JJ
cord-313312-h607itv2	15	3	vaccine	vaccine	NN
cord-313312-h607itv2	15	4	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	15	5	can	can	MD
cord-313312-h607itv2	15	6	be	be	VB
cord-313312-h607itv2	15	7	facilitated	facilitate	VBN
cord-313312-h607itv2	15	8	by	by	IN
cord-313312-h607itv2	15	9	antibody	antibody	NN
cord-313312-h607itv2	15	10	-	-	HYPH
cord-313312-h607itv2	15	11	dependent	dependent	JJ
cord-313312-h607itv2	15	12	enhancement	enhancement	NN
cord-313312-h607itv2	15	13	of	of	IN
cord-313312-h607itv2	15	14	virus	virus	NN
cord-313312-h607itv2	15	15	infection	infection	NN
cord-313312-h607itv2	15	16	,	,	,
cord-313312-h607itv2	15	17	enhancing	enhance	VBG
cord-313312-h607itv2	15	18	virus	virus	NN
cord-313312-h607itv2	15	19	uptake	uptake	NN
cord-313312-h607itv2	15	20	in	in	IN
cord-313312-h607itv2	15	21	antigen	antigen	NN
cord-313312-h607itv2	15	22	-	-	HYPH
cord-313312-h607itv2	15	23	presenting	present	VBG
cord-313312-h607itv2	15	24	cells	cell	NNS
cord-313312-h607itv2	15	25	,	,	,
cord-313312-h607itv2	15	26	and	and	CC
cord-313312-h607itv2	15	27	robust	robust	JJ
cord-313312-h607itv2	15	28	induction	induction	NN
cord-313312-h607itv2	15	29	of	of	IN
cord-313312-h607itv2	15	30	innate	innate	JJ
cord-313312-h607itv2	15	31	immune	immune	JJ
cord-313312-h607itv2	15	32	responses	response	NNS
cord-313312-h607itv2	15	33	that	that	WDT
cord-313312-h607itv2	15	34	promote	promote	VBP
cord-313312-h607itv2	15	35	vaccine	vaccine	NN
cord-313312-h607itv2	15	36	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	15	37	.	.	.
cord-313312-h607itv2	16	1	This	this	DT
cord-313312-h607itv2	16	2	review	review	NN
cord-313312-h607itv2	16	3	examines	examine	VBZ
cord-313312-h607itv2	16	4	the	the	DT
cord-313312-h607itv2	16	5	literature	literature	NN
cord-313312-h607itv2	16	6	on	on	IN
cord-313312-h607itv2	16	7	this	this	DT
cord-313312-h607itv2	16	8	topic	topic	NN
cord-313312-h607itv2	16	9	and	and	CC
cord-313312-h607itv2	16	10	examines	examine	VBZ
cord-313312-h607itv2	16	11	the	the	DT
cord-313312-h607itv2	16	12	circumstances	circumstance	NNS
cord-313312-h607itv2	16	13	where	where	WRB
cord-313312-h607itv2	16	14	pre	pre	JJ
cord-313312-h607itv2	16	15	-	-	JJ
cord-313312-h607itv2	16	16	existing	existing	JJ
cord-313312-h607itv2	16	17	antibodies	antibody	NNS
cord-313312-h607itv2	16	18	can	can	MD
cord-313312-h607itv2	16	19	inhibit	inhibit	VB
cord-313312-h607itv2	16	20	or	or	CC
cord-313312-h607itv2	16	21	enhance	enhance	VB
cord-313312-h607itv2	16	22	LAV	LAV	NNP
cord-313312-h607itv2	16	23	efficacy	efficacy	NN
cord-313312-h607itv2	16	24	.	.	.
cord-313312-h607itv2	17	1	A	a	DT
cord-313312-h607itv2	17	2	better	well	JJR
cord-313312-h607itv2	17	3	knowledge	knowledge	NN
cord-313312-h607itv2	17	4	of	of	IN
cord-313312-h607itv2	17	5	the	the	DT
cord-313312-h607itv2	17	6	underlying	underlie	VBG
cord-313312-h607itv2	17	7	mechanisms	mechanism	NNS
cord-313312-h607itv2	17	8	involved	involve	VBN
cord-313312-h607itv2	17	9	could	could	MD
cord-313312-h607itv2	17	10	allow	allow	VB
cord-313312-h607itv2	17	11	us	-PRON-	PRP
cord-313312-h607itv2	17	12	to	to	TO
cord-313312-h607itv2	17	13	better	better	RB
cord-313312-h607itv2	17	14	manage	manage	VB
cord-313312-h607itv2	17	15	immunization	immunization	NN
cord-313312-h607itv2	17	16	in	in	IN
cord-313312-h607itv2	17	17	seropositive	seropositive	JJ
cord-313312-h607itv2	17	18	individuals	individual	NNS
cord-313312-h607itv2	17	19	and	and	CC
cord-313312-h607itv2	17	20	even	even	RB
cord-313312-h607itv2	17	21	identify	identify	VB
cord-313312-h607itv2	17	22	possibilities	possibility	NNS
cord-313312-h607itv2	17	23	that	that	WDT
cord-313312-h607itv2	17	24	could	could	MD
cord-313312-h607itv2	17	25	allow	allow	VB
cord-313312-h607itv2	17	26	us	-PRON-	PRP
cord-313312-h607itv2	17	27	to	to	TO
cord-313312-h607itv2	17	28	exploit	exploit	VB
cord-313312-h607itv2	17	29	pre	pre	JJ
cord-313312-h607itv2	17	30	-	-	JJ
cord-313312-h607itv2	17	31	existing	existing	JJ
cord-313312-h607itv2	17	32	antibodies	antibody	NNS
cord-313312-h607itv2	17	33	to	to	TO
cord-313312-h607itv2	17	34	boost	boost	VB
cord-313312-h607itv2	17	35	vaccine	vaccine	NN
cord-313312-h607itv2	17	36	-	-	HYPH
cord-313312-h607itv2	17	37	induced	induce	VBN
cord-313312-h607itv2	17	38	responses	response	NNS
cord-313312-h607itv2	17	39	for	for	IN
cord-313312-h607itv2	17	40	improved	improved	JJ
cord-313312-h607itv2	17	41	vaccine	vaccine	NN
cord-313312-h607itv2	17	42	efficacy	efficacy	NN
cord-313312-h607itv2	17	43	.	.	.
cord-313312-h607itv2	18	1	"	"	``
cord-313312-h607itv2	18	2	It	-PRON-	PRP
cord-313312-h607itv2	18	3	's	be	VBZ
cord-313312-h607itv2	18	4	time	time	NN
cord-313312-h607itv2	18	5	to	to	TO
cord-313312-h607itv2	18	6	close	close	VB
cord-313312-h607itv2	18	7	the	the	DT
cord-313312-h607itv2	18	8	book	book	NN
cord-313312-h607itv2	18	9	on	on	IN
cord-313312-h607itv2	18	10	infectious	infectious	JJ
cord-313312-h607itv2	18	11	diseases	disease	NNS
cord-313312-h607itv2	18	12	,	,	,
cord-313312-h607itv2	18	13	declare	declare	VB
cord-313312-h607itv2	18	14	the	the	DT
cord-313312-h607itv2	18	15	war	war	NN
cord-313312-h607itv2	18	16	against	against	IN
cord-313312-h607itv2	18	17	pestilence	pestilence	NN
cord-313312-h607itv2	18	18	won	win	VBD
cord-313312-h607itv2	18	19	,	,	,
cord-313312-h607itv2	18	20	and	and	CC
cord-313312-h607itv2	18	21	shift	shift	VB
cord-313312-h607itv2	18	22	national	national	JJ
cord-313312-h607itv2	18	23	resources	resource	NNS
cord-313312-h607itv2	18	24	to	to	IN
cord-313312-h607itv2	18	25	such	such	JJ
cord-313312-h607itv2	18	26	chronic	chronic	JJ
cord-313312-h607itv2	18	27	problems	problem	NNS
cord-313312-h607itv2	18	28	as	as	IN
cord-313312-h607itv2	18	29	cancer	cancer	NN
cord-313312-h607itv2	18	30	and	and	CC
cord-313312-h607itv2	18	31	heart	heart	NN
cord-313312-h607itv2	18	32	disease	disease	NN
cord-313312-h607itv2	18	33	"	"	''
cord-313312-h607itv2	18	34	[	[	-LRB-
cord-313312-h607itv2	18	35	1	1	CD
cord-313312-h607itv2	18	36	]	]	-RRB-
cord-313312-h607itv2	18	37	.	.	.
cord-313312-h607itv2	19	1	Contrary	contrary	JJ
cord-313312-h607itv2	19	2	to	to	IN
cord-313312-h607itv2	19	3	this	this	DT
cord-313312-h607itv2	19	4	infamous	infamous	JJ
cord-313312-h607itv2	19	5	statement	statement	NN
cord-313312-h607itv2	19	6	,	,	,
cord-313312-h607itv2	19	7	long	long	RB
cord-313312-h607itv2	19	8	misattributed	misattribute	VBN
cord-313312-h607itv2	19	9	to	to	IN
cord-313312-h607itv2	19	10	the	the	DT
cord-313312-h607itv2	19	11	former	former	JJ
cord-313312-h607itv2	19	12	US	US	NNP
cord-313312-h607itv2	19	13	Surgeon	Surgeon	NNP
cord-313312-h607itv2	19	14	General	General	NNP
cord-313312-h607itv2	19	15	Dr.	Dr.	NNP
cord-313312-h607itv2	19	16	William	William	NNP
cord-313312-h607itv2	19	17	H.	H.	NNP
cord-313312-h607itv2	19	18	Stewart	Stewart	NNP
cord-313312-h607itv2	19	19	,	,	,
cord-313312-h607itv2	19	20	and	and	CC
cord-313312-h607itv2	19	21	despite	despite	IN
cord-313312-h607itv2	19	22	advances	advance	NNS
cord-313312-h607itv2	19	23	in	in	IN
cord-313312-h607itv2	19	24	healthcare	healthcare	NN
cord-313312-h607itv2	19	25	and	and	CC
cord-313312-h607itv2	19	26	technology	technology	NN
cord-313312-h607itv2	19	27	,	,	,
cord-313312-h607itv2	19	28	we	-PRON-	PRP
cord-313312-h607itv2	19	29	remain	remain	VBP
cord-313312-h607itv2	19	30	extremely	extremely	RB
cord-313312-h607itv2	19	31	vulnerable	vulnerable	JJ
cord-313312-h607itv2	19	32	to	to	IN
cord-313312-h607itv2	19	33	the	the	DT
cord-313312-h607itv2	19	34	threat	threat	NN
cord-313312-h607itv2	19	35	of	of	IN
cord-313312-h607itv2	19	36	communicable	communicable	JJ
cord-313312-h607itv2	19	37	diseases	disease	NNS
cord-313312-h607itv2	19	38	.	.	.
cord-313312-h607itv2	20	1	In	in	IN
cord-313312-h607itv2	20	2	the	the	DT
cord-313312-h607itv2	20	3	last	last	JJ
cord-313312-h607itv2	20	4	ten	ten	CD
cord-313312-h607itv2	20	5	years	year	NNS
cord-313312-h607itv2	20	6	alone	alone	RB
cord-313312-h607itv2	20	7	,	,	,
cord-313312-h607itv2	20	8	we	-PRON-	PRP
cord-313312-h607itv2	20	9	have	have	VBP
cord-313312-h607itv2	20	10	experienced	experience	VBN
cord-313312-h607itv2	20	11	the	the	DT
cord-313312-h607itv2	20	12	pandemic	pandemic	NN
cord-313312-h607itv2	20	13	spread	spread	NN
cord-313312-h607itv2	20	14	of	of	IN
cord-313312-h607itv2	20	15	swine	swine	NN
cord-313312-h607itv2	20	16	-	-	HYPH
cord-313312-h607itv2	20	17	origin	origin	NN
cord-313312-h607itv2	20	18	H1N1	H1N1	NNP
cord-313312-h607itv2	20	19	influenza	influenza	NN
cord-313312-h607itv2	20	20	,	,	,
cord-313312-h607itv2	20	21	the	the	DT
cord-313312-h607itv2	20	22	West	west	JJ
cord-313312-h607itv2	20	23	African	African	NNP
cord-313312-h607itv2	20	24	Ebola	Ebola	NNP
cord-313312-h607itv2	20	25	epidemic	epidemic	NN
cord-313312-h607itv2	20	26	,	,	,
cord-313312-h607itv2	20	27	the	the	DT
cord-313312-h607itv2	20	28	resurgence	resurgence	NN
cord-313312-h607itv2	20	29	of	of	IN
cord-313312-h607itv2	20	30	yellow	yellow	JJ
cord-313312-h607itv2	20	31	fever	fever	NN
cord-313312-h607itv2	20	32	,	,	,
cord-313312-h607itv2	20	33	the	the	DT
cord-313312-h607itv2	20	34	Zika	Zika	NNP
cord-313312-h607itv2	20	35	virus	virus	NN
cord-313312-h607itv2	20	36	emergency	emergency	NN
cord-313312-h607itv2	20	37	,	,	,
cord-313312-h607itv2	20	38	and	and	CC
cord-313312-h607itv2	20	39	the	the	DT
cord-313312-h607itv2	20	40	return	return	NN
cord-313312-h607itv2	20	41	of	of	IN
cord-313312-h607itv2	20	42	a	a	DT
cord-313312-h607itv2	20	43	global	global	JJ
cord-313312-h607itv2	20	44	coronavirus	coronavirus	NN
cord-313312-h607itv2	20	45	threat	threat	NN
cord-313312-h607itv2	20	46	[	[	-LRB-
cord-313312-h607itv2	20	47	2	2	CD
cord-313312-h607itv2	20	48	]	]	-RRB-
cord-313312-h607itv2	20	49	[	[	-LRB-
cord-313312-h607itv2	20	50	3	3	CD
cord-313312-h607itv2	20	51	]	]	-RRB-
cord-313312-h607itv2	20	52	[	[	-LRB-
cord-313312-h607itv2	20	53	4	4	CD
cord-313312-h607itv2	20	54	]	]	-RRB-
cord-313312-h607itv2	20	55	[	[	-LRB-
cord-313312-h607itv2	20	56	5	5	CD
cord-313312-h607itv2	20	57	]	]	-RRB-
cord-313312-h607itv2	20	58	[	[	-LRB-
cord-313312-h607itv2	20	59	6	6	CD
cord-313312-h607itv2	20	60	]	]	-RRB-
cord-313312-h607itv2	20	61	.	.	.
cord-313312-h607itv2	21	1	With	with	IN
cord-313312-h607itv2	21	2	the	the	DT
cord-313312-h607itv2	21	3	continued	continued	JJ
cord-313312-h607itv2	21	4	emergence	emergence	NN
cord-313312-h607itv2	21	5	and	and	CC
cord-313312-h607itv2	21	6	re	re	NN
cord-313312-h607itv2	21	7	-	-	NN
cord-313312-h607itv2	21	8	emergence	emergence	NN
cord-313312-h607itv2	21	9	of	of	IN
cord-313312-h607itv2	21	10	new	new	JJ
cord-313312-h607itv2	21	11	and	and	CC
cord-313312-h607itv2	21	12	current	current	JJ
cord-313312-h607itv2	21	13	viral	viral	JJ
cord-313312-h607itv2	21	14	pathogens	pathogen	NNS
cord-313312-h607itv2	21	15	,	,	,
cord-313312-h607itv2	21	16	it	-PRON-	PRP
cord-313312-h607itv2	21	17	is	be	VBZ
cord-313312-h607itv2	21	18	imperative	imperative	JJ
cord-313312-h607itv2	21	19	that	that	IN
cord-313312-h607itv2	21	20	we	-PRON-	PRP
cord-313312-h607itv2	21	21	continue	continue	VBP
cord-313312-h607itv2	21	22	to	to	TO
cord-313312-h607itv2	21	23	design	design	VB
cord-313312-h607itv2	21	24	new	new	JJ
cord-313312-h607itv2	21	25	strategies	strategy	NNS
cord-313312-h607itv2	21	26	to	to	TO
cord-313312-h607itv2	21	27	combat	combat	VB
cord-313312-h607itv2	21	28	their	-PRON-	PRP$
cord-313312-h607itv2	21	29	spread	spread	NN
cord-313312-h607itv2	21	30	and	and	CC
cord-313312-h607itv2	21	31	prevent	prevent	VB
cord-313312-h607itv2	21	32	human	human	JJ
cord-313312-h607itv2	21	33	disease	disease	NN
cord-313312-h607itv2	21	34	.	.	.
cord-313312-h607itv2	22	1	Among	among	IN
cord-313312-h607itv2	22	2	the	the	DT
cord-313312-h607itv2	22	3	various	various	JJ
cord-313312-h607itv2	22	4	methods	method	NNS
cord-313312-h607itv2	22	5	to	to	TO
cord-313312-h607itv2	22	6	impede	impede	VB
cord-313312-h607itv2	22	7	viral	viral	JJ
cord-313312-h607itv2	22	8	transmission	transmission	NN
cord-313312-h607itv2	22	9	,	,	,
cord-313312-h607itv2	22	10	vaccines	vaccine	NNS
cord-313312-h607itv2	22	11	are	be	VBP
cord-313312-h607itv2	22	12	widely	widely	RB
cord-313312-h607itv2	22	13	heralded	herald	VBN
cord-313312-h607itv2	22	14	as	as	IN
cord-313312-h607itv2	22	15	one	one	CD
cord-313312-h607itv2	22	16	of	of	IN
cord-313312-h607itv2	22	17	the	the	DT
cord-313312-h607itv2	22	18	most	most	RBS
cord-313312-h607itv2	22	19	effective	effective	JJ
cord-313312-h607itv2	22	20	medical	medical	JJ
cord-313312-h607itv2	22	21	interventions	intervention	NNS
cord-313312-h607itv2	22	22	.	.	.
cord-313312-h607itv2	23	1	Indeed	indeed	RB
cord-313312-h607itv2	23	2	,	,	,
cord-313312-h607itv2	23	3	since	since	IN
cord-313312-h607itv2	23	4	the	the	DT
cord-313312-h607itv2	23	5	pivotal	pivotal	JJ
cord-313312-h607itv2	23	6	discovery	discovery	NN
cord-313312-h607itv2	23	7	by	by	IN
cord-313312-h607itv2	23	8	Edward	Edward	NNP
cord-313312-h607itv2	23	9	Jenner	Jenner	NNP
cord-313312-h607itv2	23	10	over	over	IN
cord-313312-h607itv2	23	11	two	two	CD
cord-313312-h607itv2	23	12	hundred	hundred	CD
cord-313312-h607itv2	23	13	years	year	NNS
cord-313312-h607itv2	23	14	ago	ago	RB
cord-313312-h607itv2	23	15	,	,	,
cord-313312-h607itv2	23	16	vaccination	vaccination	NN
cord-313312-h607itv2	23	17	has	have	VBZ
cord-313312-h607itv2	23	18	seen	see	VBN
cord-313312-h607itv2	23	19	tremendous	tremendous	JJ
cord-313312-h607itv2	23	20	success	success	NN
cord-313312-h607itv2	23	21	in	in	IN
cord-313312-h607itv2	23	22	reducing	reduce	VBG
cord-313312-h607itv2	23	23	the	the	DT
cord-313312-h607itv2	23	24	burden	burden	NN
cord-313312-h607itv2	23	25	of	of	IN
cord-313312-h607itv2	23	26	viral	viral	JJ
cord-313312-h607itv2	23	27	diseases	disease	NNS
cord-313312-h607itv2	23	28	against	against	IN
cord-313312-h607itv2	23	29	wild	wild	JJ
cord-313312-h607itv2	23	30	-	-	HYPH
cord-313312-h607itv2	23	31	type	type	NN
cord-313312-h607itv2	23	32	virus	virus	NN
cord-313312-h607itv2	23	33	infections	infection	NNS
cord-313312-h607itv2	23	34	and	and	CC
cord-313312-h607itv2	23	35	not	not	RB
cord-313312-h607itv2	23	36	cause	cause	VB
cord-313312-h607itv2	23	37	worse	bad	JJR
cord-313312-h607itv2	23	38	disease	disease	NN
cord-313312-h607itv2	23	39	outcomes	outcome	NNS
cord-313312-h607itv2	23	40	.	.	.
cord-313312-h607itv2	24	1	For	for	IN
cord-313312-h607itv2	24	2	vaccines	vaccine	NNS
cord-313312-h607itv2	24	3	that	that	WDT
cord-313312-h607itv2	24	4	are	be	VBP
cord-313312-h607itv2	24	5	administered	administer	VBN
cord-313312-h607itv2	24	6	to	to	IN
cord-313312-h607itv2	24	7	neonates	neonate	NNS
cord-313312-h607itv2	24	8	,	,	,
cord-313312-h607itv2	24	9	the	the	DT
cord-313312-h607itv2	24	10	presence	presence	NN
cord-313312-h607itv2	24	11	of	of	IN
cord-313312-h607itv2	24	12	passively	passively	RB
cord-313312-h607itv2	24	13	acquired	acquire	VBN
cord-313312-h607itv2	24	14	maternal	maternal	JJ
cord-313312-h607itv2	24	15	antibodies	antibody	NNS
cord-313312-h607itv2	24	16	within	within	IN
cord-313312-h607itv2	24	17	the	the	DT
cord-313312-h607itv2	24	18	first	first	JJ
cord-313312-h607itv2	24	19	six	six	CD
cord-313312-h607itv2	24	20	months	month	NNS
cord-313312-h607itv2	24	21	may	may	MD
cord-313312-h607itv2	24	22	also	also	RB
cord-313312-h607itv2	24	23	interfere	interfere	VB
cord-313312-h607itv2	24	24	with	with	IN
cord-313312-h607itv2	24	25	vaccination	vaccination	NN
cord-313312-h607itv2	24	26	[	[	-LRB-
cord-313312-h607itv2	24	27	21	21	CD
cord-313312-h607itv2	24	28	,	,	,
cord-313312-h607itv2	24	29	22	22	CD
cord-313312-h607itv2	24	30	]	]	-RRB-
cord-313312-h607itv2	24	31	.	.	.
cord-313312-h607itv2	25	1	The	the	DT
cord-313312-h607itv2	25	2	potential	potential	JJ
cord-313312-h607itv2	25	3	effects	effect	NNS
cord-313312-h607itv2	25	4	of	of	IN
cord-313312-h607itv2	25	5	pre	pre	JJ
cord-313312-h607itv2	25	6	-	-	JJ
cord-313312-h607itv2	25	7	existing	existing	JJ
cord-313312-h607itv2	25	8	antibodies	antibody	NNS
cord-313312-h607itv2	25	9	on	on	IN
cord-313312-h607itv2	25	10	LAV	LAV	NNP
cord-313312-h607itv2	25	11	and	and	CC
cord-313312-h607itv2	25	12	virally	virally	RB
cord-313312-h607itv2	25	13	vectored	vectore	VBN
cord-313312-h607itv2	25	14	antigens	antigen	NNS
cord-313312-h607itv2	25	15	will	will	MD
cord-313312-h607itv2	25	16	hence	hence	RB
cord-313312-h607itv2	25	17	be	be	VB
cord-313312-h607itv2	25	18	the	the	DT
cord-313312-h607itv2	25	19	focus	focus	NN
cord-313312-h607itv2	25	20	of	of	IN
cord-313312-h607itv2	25	21	this	this	DT
cord-313312-h607itv2	25	22	review	review	NN
cord-313312-h607itv2	25	23	.	.	.
cord-313312-h607itv2	26	1	In	in	IN
cord-313312-h607itv2	26	2	this	this	DT
cord-313312-h607itv2	26	3	review	review	NN
cord-313312-h607itv2	26	4	,	,	,
cord-313312-h607itv2	26	5	we	-PRON-	PRP
cord-313312-h607itv2	26	6	examine	examine	VBP
cord-313312-h607itv2	26	7	the	the	DT
cord-313312-h607itv2	26	8	scenarios	scenario	NNS
cord-313312-h607itv2	26	9	in	in	IN
cord-313312-h607itv2	26	10	which	which	WDT
cord-313312-h607itv2	26	11	pre	pre	JJ
cord-313312-h607itv2	26	12	-	-	JJ
cord-313312-h607itv2	26	13	existing	existing	JJ
cord-313312-h607itv2	26	14	antibodies	antibody	NNS
cord-313312-h607itv2	26	15	can	can	MD
cord-313312-h607itv2	26	16	either	either	CC
cord-313312-h607itv2	26	17	enhance	enhance	VB
cord-313312-h607itv2	26	18	or	or	CC
cord-313312-h607itv2	26	19	inhibit	inhibit	VB
cord-313312-h607itv2	26	20	LAV	LAV	NNP
cord-313312-h607itv2	26	21	efficacy	efficacy	NN
cord-313312-h607itv2	26	22	,	,	,
cord-313312-h607itv2	26	23	as	as	RB
cord-313312-h607itv2	26	24	well	well	RB
cord-313312-h607itv2	26	25	as	as	IN
cord-313312-h607itv2	26	26	the	the	DT
cord-313312-h607itv2	26	27	underlying	underlie	VBG
cord-313312-h607itv2	26	28	mechanisms	mechanism	NNS
cord-313312-h607itv2	26	29	involved	involve	VBN
cord-313312-h607itv2	26	30	.	.	.
cord-313312-h607itv2	27	1	A	a	DT
cord-313312-h607itv2	27	2	better	well	JJR
cord-313312-h607itv2	27	3	understanding	understanding	NN
cord-313312-h607itv2	27	4	will	will	MD
cord-313312-h607itv2	27	5	allow	allow	VB
cord-313312-h607itv2	27	6	us	-PRON-	PRP
cord-313312-h607itv2	27	7	to	to	TO
cord-313312-h607itv2	27	8	tailor	tailor	VB
cord-313312-h607itv2	27	9	our	-PRON-	PRP$
cord-313312-h607itv2	27	10	vaccination	vaccination	NN
cord-313312-h607itv2	27	11	schedules	schedule	NNS
cord-313312-h607itv2	27	12	or	or	CC
cord-313312-h607itv2	27	13	vaccine	vaccine	NN
cord-313312-h607itv2	27	14	doses	dose	NNS
cord-313312-h607itv2	27	15	,	,	,
cord-313312-h607itv2	27	16	to	to	TO
cord-313312-h607itv2	27	17	ensure	ensure	VB
cord-313312-h607itv2	27	18	that	that	IN
cord-313312-h607itv2	27	19	LAV	LAV	NNP
cord-313312-h607itv2	27	20	efficacy	efficacy	NN
cord-313312-h607itv2	27	21	will	will	MD
cord-313312-h607itv2	27	22	not	not	RB
cord-313312-h607itv2	27	23	be	be	VB
cord-313312-h607itv2	27	24	compromised	compromise	VBN
cord-313312-h607itv2	27	25	by	by	IN
cord-313312-h607itv2	27	26	the	the	DT
cord-313312-h607itv2	27	27	presence	presence	NN
cord-313312-h607itv2	27	28	of	of	IN
cord-313312-h607itv2	27	29	pre	pre	JJ
cord-313312-h607itv2	27	30	-	-	JJ
cord-313312-h607itv2	27	31	existing	existing	JJ
cord-313312-h607itv2	27	32	immunity	immunity	NN
cord-313312-h607itv2	27	33	.	.	.
cord-313312-h607itv2	28	1	Prior	prior	RB
cord-313312-h607itv2	28	2	to	to	IN
cord-313312-h607itv2	28	3	the	the	DT
cord-313312-h607itv2	28	4	advent	advent	NN
cord-313312-h607itv2	28	5	of	of	IN
cord-313312-h607itv2	28	6	vaccination	vaccination	NN
cord-313312-h607itv2	28	7	,	,	,
cord-313312-h607itv2	28	8	the	the	DT
cord-313312-h607itv2	28	9	incidence	incidence	NN
cord-313312-h607itv2	28	10	rate	rate	NN
cord-313312-h607itv2	28	11	of	of	IN
cord-313312-h607itv2	28	12	measles	measle	NNS
cord-313312-h607itv2	28	13	was	be	VBD
cord-313312-h607itv2	28	14	so	so	RB
cord-313312-h607itv2	28	15	high	high	JJ
cord-313312-h607itv2	28	16	that	that	DT
cord-313312-h607itv2	28	17	infection	infection	NN
cord-313312-h607itv2	28	18	by	by	IN
cord-313312-h607itv2	28	19	the	the	DT
cord-313312-h607itv2	28	20	measles	measle	NNS
cord-313312-h607itv2	28	21	virus	virus	NN
cord-313312-h607itv2	28	22	was	be	VBD
cord-313312-h607itv2	28	23	basically	basically	RB
cord-313312-h607itv2	28	24	considered	consider	VBN
cord-313312-h607itv2	28	25	an	an	DT
cord-313312-h607itv2	28	26	inevitability	inevitability	NN
cord-313312-h607itv2	28	27	[	[	-LRB-
cord-313312-h607itv2	28	28	23	23	CD
cord-313312-h607itv2	28	29	,	,	,
cord-313312-h607itv2	28	30	24	24	CD
cord-313312-h607itv2	28	31	]	]	-RRB-
cord-313312-h607itv2	28	32	.	.	.
cord-313312-h607itv2	29	1	The	the	DT
cord-313312-h607itv2	29	2	virus	virus	NN
cord-313312-h607itv2	29	3	,	,	,
cord-313312-h607itv2	29	4	which	which	WDT
cord-313312-h607itv2	29	5	is	be	VBZ
cord-313312-h607itv2	29	6	spread	spread	VBN
cord-313312-h607itv2	29	7	by	by	IN
cord-313312-h607itv2	29	8	the	the	DT
cord-313312-h607itv2	29	9	respiratory	respiratory	JJ
cord-313312-h607itv2	29	10	route	route	NN
cord-313312-h607itv2	29	11	,	,	,
cord-313312-h607itv2	29	12	is	be	VBZ
cord-313312-h607itv2	29	13	highly	highly	RB
cord-313312-h607itv2	29	14	contagious	contagious	JJ
cord-313312-h607itv2	29	15	and	and	CC
cord-313312-h607itv2	29	16	infects	infect	VBZ
cord-313312-h607itv2	29	17	over	over	IN
cord-313312-h607itv2	29	18	90	90	CD
cord-313312-h607itv2	29	19	%	%	NN
cord-313312-h607itv2	29	20	of	of	IN
cord-313312-h607itv2	29	21	individuals	individual	NNS
cord-313312-h607itv2	29	22	by	by	IN
cord-313312-h607itv2	29	23	age	age	NN
cord-313312-h607itv2	29	24	18	18	CD
cord-313312-h607itv2	29	25	in	in	IN
cord-313312-h607itv2	29	26	the	the	DT
cord-313312-h607itv2	29	27	pre	pre	JJ
cord-313312-h607itv2	29	28	-	-	JJ
cord-313312-h607itv2	29	29	vaccination	vaccination	JJ
cord-313312-h607itv2	29	30	era	era	NN
cord-313312-h607itv2	29	31	[	[	-LRB-
cord-313312-h607itv2	29	32	24	24	CD
cord-313312-h607itv2	29	33	,	,	,
cord-313312-h607itv2	29	34	25	25	CD
cord-313312-h607itv2	29	35	]	]	-RRB-
cord-313312-h607itv2	29	36	.	.	.
cord-313312-h607itv2	30	1	About	about	RB
cord-313312-h607itv2	30	2	seven	seven	CD
cord-313312-h607itv2	30	3	to	to	TO
cord-313312-h607itv2	30	4	eight	eight	CD
cord-313312-h607itv2	30	5	million	million	CD
cord-313312-h607itv2	30	6	children	child	NNS
cord-313312-h607itv2	30	7	were	be	VBD
cord-313312-h607itv2	30	8	estimated	estimate	VBN
cord-313312-h607itv2	30	9	to	to	TO
cord-313312-h607itv2	30	10	have	have	VB
cord-313312-h607itv2	30	11	died	die	VBN
cord-313312-h607itv2	30	12	from	from	IN
cord-313312-h607itv2	30	13	measles	measles	NN
cord-313312-h607itv2	30	14	infection	infection	NN
cord-313312-h607itv2	30	15	each	each	DT
cord-313312-h607itv2	30	16	year	year	NN
cord-313312-h607itv2	30	17	during	during	IN
cord-313312-h607itv2	30	18	this	this	DT
cord-313312-h607itv2	30	19	period	period	NN
cord-313312-h607itv2	30	20	,	,	,
cord-313312-h607itv2	30	21	with	with	IN
cord-313312-h607itv2	30	22	many	many	JJ
cord-313312-h607itv2	30	23	others	other	NNS
cord-313312-h607itv2	30	24	suffering	suffer	VBG
cord-313312-h607itv2	30	25	from	from	IN
cord-313312-h607itv2	30	26	disease	disease	NN
cord-313312-h607itv2	30	27	complications	complication	NNS
cord-313312-h607itv2	30	28	[	[	-LRB-
cord-313312-h607itv2	30	29	26	26	CD
cord-313312-h607itv2	30	30	]	]	-RRB-
cord-313312-h607itv2	30	31	.	.	.
cord-313312-h607itv2	31	1	However	however	RB
cord-313312-h607itv2	31	2	,	,	,
cord-313312-h607itv2	31	3	in	in	IN
cord-313312-h607itv2	31	4	1936	1936	CD
cord-313312-h607itv2	31	5	,	,	,
cord-313312-h607itv2	31	6	society	society	NN
cord-313312-h607itv2	31	7	experienced	experience	VBD
cord-313312-h607itv2	31	8	a	a	DT
cord-313312-h607itv2	31	9	turning	turning	NN
cord-313312-h607itv2	31	10	point	point	NN
cord-313312-h607itv2	31	11	in	in	IN
cord-313312-h607itv2	31	12	the	the	DT
cord-313312-h607itv2	31	13	fight	fight	NN
cord-313312-h607itv2	31	14	against	against	IN
cord-313312-h607itv2	31	15	measles	measle	NNS
cord-313312-h607itv2	31	16	with	with	IN
cord-313312-h607itv2	31	17	the	the	DT
cord-313312-h607itv2	31	18	development	development	NN
cord-313312-h607itv2	31	19	of	of	IN
cord-313312-h607itv2	31	20	the	the	DT
cord-313312-h607itv2	31	21	first	first	JJ
cord-313312-h607itv2	31	22	live	live	RB
cord-313312-h607itv2	31	23	-	-	HYPH
cord-313312-h607itv2	31	24	attenuated	attenuate	VBN
cord-313312-h607itv2	31	25	measles	measle	NNS
cord-313312-h607itv2	31	26	vaccine	vaccine	NN
cord-313312-h607itv2	31	27	(	(	-LRB-
cord-313312-h607itv2	31	28	MV	MV	NNP
cord-313312-h607itv2	31	29	)	)	-RRB-
cord-313312-h607itv2	31	30	[	[	-LRB-
cord-313312-h607itv2	31	31	27	27	CD
cord-313312-h607itv2	31	32	]	]	-RRB-
cord-313312-h607itv2	31	33	.	.	.
cord-313312-h607itv2	32	1	The	the	DT
cord-313312-h607itv2	32	2	live	live	RB
cord-313312-h607itv2	32	3	-	-	HYPH
cord-313312-h607itv2	32	4	attenuated	attenuated	JJ
cord-313312-h607itv2	32	5	MV	MV	NNP
cord-313312-h607itv2	32	6	is	be	VBZ
cord-313312-h607itv2	32	7	one	one	CD
cord-313312-h607itv2	32	8	example	example	NN
cord-313312-h607itv2	32	9	of	of	IN
cord-313312-h607itv2	32	10	a	a	DT
cord-313312-h607itv2	32	11	highly	highly	RB
cord-313312-h607itv2	32	12	successful	successful	JJ
cord-313312-h607itv2	32	13	LAV	LAV	NNP
cord-313312-h607itv2	32	14	,	,	,
cord-313312-h607itv2	32	15	and	and	CC
cord-313312-h607itv2	32	16	its	-PRON-	PRP$
cord-313312-h607itv2	32	17	introduction	introduction	NN
cord-313312-h607itv2	32	18	has	have	VBZ
cord-313312-h607itv2	32	19	transformed	transform	VBN
cord-313312-h607itv2	32	20	measles	measle	NNS
cord-313312-h607itv2	32	21	from	from	IN
cord-313312-h607itv2	32	22	a	a	DT
cord-313312-h607itv2	32	23	complicated	complicated	JJ
cord-313312-h607itv2	32	24	disease	disease	NN
cord-313312-h607itv2	32	25	into	into	IN
cord-313312-h607itv2	32	26	a	a	DT
cord-313312-h607itv2	32	27	triviality	triviality	NN
cord-313312-h607itv2	32	28	in	in	IN
cord-313312-h607itv2	32	29	most	most	RBS
cord-313312-h607itv2	32	30	developed	developed	JJ
cord-313312-h607itv2	32	31	countries	country	NNS
cord-313312-h607itv2	32	32	,	,	,
cord-313312-h607itv2	32	33	although	although	IN
cord-313312-h607itv2	32	34	measles	measle	NNS
cord-313312-h607itv2	32	35	still	still	RB
cord-313312-h607itv2	32	36	forms	form	VBZ
cord-313312-h607itv2	32	37	a	a	DT
cord-313312-h607itv2	32	38	significant	significant	JJ
cord-313312-h607itv2	32	39	disease	disease	NN
cord-313312-h607itv2	32	40	burden	burden	NN
cord-313312-h607itv2	32	41	in	in	IN
cord-313312-h607itv2	32	42	developing	develop	VBG
cord-313312-h607itv2	32	43	nations	nation	NNS
cord-313312-h607itv2	32	44	[	[	-LRB-
cord-313312-h607itv2	32	45	28	28	CD
cord-313312-h607itv2	32	46	]	]	-RRB-
cord-313312-h607itv2	32	47	[	[	-LRB-
cord-313312-h607itv2	32	48	29	29	CD
cord-313312-h607itv2	32	49	]	]	-RRB-
cord-313312-h607itv2	32	50	[	[	-LRB-
cord-313312-h607itv2	32	51	30	30	CD
cord-313312-h607itv2	32	52	]	]	-RRB-
cord-313312-h607itv2	32	53	.	.	.
cord-313312-h607itv2	33	1	The	the	DT
cord-313312-h607itv2	33	2	wild	wild	JJ
cord-313312-h607itv2	33	3	-	-	HYPH
cord-313312-h607itv2	33	4	type	type	NN
cord-313312-h607itv2	33	5	virus	virus	NN
cord-313312-h607itv2	33	6	was	be	VBD
cord-313312-h607itv2	33	7	first	first	RB
cord-313312-h607itv2	33	8	isolated	isolate	VBN
cord-313312-h607itv2	33	9	in	in	IN
cord-313312-h607itv2	33	10	1954	1954	CD
cord-313312-h607itv2	33	11	by	by	IN
cord-313312-h607itv2	33	12	Dr.	Dr.	NNP
cord-313312-h607itv2	33	13	John	John	NNP
cord-313312-h607itv2	33	14	F.	F.	NNP
cord-313312-h607itv2	33	15	Enders	Enders	NNP
cord-313312-h607itv2	33	16	and	and	CC
cord-313312-h607itv2	33	17	his	-PRON-	PRP$
cord-313312-h607itv2	33	18	team	team	NN
cord-313312-h607itv2	33	19	from	from	IN
cord-313312-h607itv2	33	20	the	the	DT
cord-313312-h607itv2	33	21	blood	blood	NN
cord-313312-h607itv2	33	22	of	of	IN
cord-313312-h607itv2	33	23	an	an	DT
cord-313312-h607itv2	33	24	11-year	11-year	JJ
cord-313312-h607itv2	33	25	-	-	HYPH
cord-313312-h607itv2	33	26	old	old	JJ
cord-313312-h607itv2	33	27	boy	boy	NN
cord-313312-h607itv2	33	28	named	name	VBN
cord-313312-h607itv2	33	29	David	David	NNP
cord-313312-h607itv2	33	30	Edmonston	Edmonston	NNP
cord-313312-h607itv2	33	31	,	,	,
cord-313312-h607itv2	33	32	who	who	WP
cord-313312-h607itv2	33	33	became	become	VBD
cord-313312-h607itv2	33	34	the	the	DT
cord-313312-h607itv2	33	35	namesake	namesake	NN
cord-313312-h607itv2	33	36	of	of	IN
cord-313312-h607itv2	33	37	the	the	DT
cord-313312-h607itv2	33	38	viral	viral	JJ
cord-313312-h607itv2	33	39	strain	strain	NN
cord-313312-h607itv2	33	40	that	that	WDT
cord-313312-h607itv2	33	41	would	would	MD
cord-313312-h607itv2	33	42	eventually	eventually	RB
cord-313312-h607itv2	33	43	become	become	VB
cord-313312-h607itv2	33	44	the	the	DT
cord-313312-h607itv2	33	45	first	first	JJ
cord-313312-h607itv2	33	46	measles	measles	NN
cord-313312-h607itv2	33	47	vaccine	vaccine	NN
cord-313312-h607itv2	33	48	[	[	-LRB-
cord-313312-h607itv2	33	49	31	31	CD
cord-313312-h607itv2	33	50	]	]	-RRB-
cord-313312-h607itv2	33	51	.	.	.
cord-313312-h607itv2	34	1	Serial	serial	JJ
cord-313312-h607itv2	34	2	passage	passage	NN
cord-313312-h607itv2	34	3	of	of	IN
cord-313312-h607itv2	34	4	the	the	DT
cord-313312-h607itv2	34	5	wild	wild	JJ
cord-313312-h607itv2	34	6	-	-	HYPH
cord-313312-h607itv2	34	7	type	type	NN
cord-313312-h607itv2	34	8	Edmonston	Edmonston	NNP
cord-313312-h607itv2	34	9	strain	strain	NN
cord-313312-h607itv2	34	10	in	in	IN
cord-313312-h607itv2	34	11	human	human	JJ
cord-313312-h607itv2	34	12	and	and	CC
cord-313312-h607itv2	34	13	chicken	chicken	NN
cord-313312-h607itv2	34	14	embryo	embryo	NN
cord-313312-h607itv2	34	15	fibroblast	fibroblast	NN
cord-313312-h607itv2	34	16	tissue	tissue	NN
cord-313312-h607itv2	34	17	culture	culture	NN
cord-313312-h607itv2	34	18	resulted	result	VBD
cord-313312-h607itv2	34	19	in	in	IN
cord-313312-h607itv2	34	20	a	a	DT
cord-313312-h607itv2	34	21	virus	virus	NN
cord-313312-h607itv2	34	22	with	with	IN
cord-313312-h607itv2	34	23	reduced	reduce	VBN
cord-313312-h607itv2	34	24	virulence	virulence	NN
cord-313312-h607itv2	34	25	.	.	.
cord-313312-h607itv2	35	1	However	however	RB
cord-313312-h607itv2	35	2	,	,	,
cord-313312-h607itv2	35	3	the	the	DT
cord-313312-h607itv2	35	4	ability	ability	NN
cord-313312-h607itv2	35	5	of	of	IN
cord-313312-h607itv2	35	6	the	the	DT
cord-313312-h607itv2	35	7	parental	parental	JJ
cord-313312-h607itv2	35	8	strain	strain	NN
cord-313312-h607itv2	35	9	to	to	TO
cord-313312-h607itv2	35	10	induce	induce	VB
cord-313312-h607itv2	35	11	protective	protective	JJ
cord-313312-h607itv2	35	12	immunity	immunity	NN
cord-313312-h607itv2	35	13	is	be	VBZ
cord-313312-h607itv2	35	14	retained	retain	VBN
cord-313312-h607itv2	35	15	.	.	.
cord-313312-h607itv2	36	1	The	the	DT
cord-313312-h607itv2	36	2	MV	MV	NNP
cord-313312-h607itv2	36	3	is	be	VBZ
cord-313312-h607itv2	36	4	highly	highly	RB
cord-313312-h607itv2	36	5	immunogenic	immunogenic	JJ
cord-313312-h607itv2	36	6	,	,	,
cord-313312-h607itv2	36	7	inducing	induce	VBG
cord-313312-h607itv2	36	8	both	both	CC
cord-313312-h607itv2	36	9	humoral	humoral	JJ
cord-313312-h607itv2	36	10	and	and	CC
cord-313312-h607itv2	36	11	cellular	cellular	JJ
cord-313312-h607itv2	36	12	immunity	immunity	NN
cord-313312-h607itv2	36	13	at	at	IN
cord-313312-h607itv2	36	14	magnitudes	magnitude	NNS
cord-313312-h607itv2	36	15	comparable	comparable	JJ
cord-313312-h607itv2	36	16	to	to	IN
cord-313312-h607itv2	36	17	that	that	DT
cord-313312-h607itv2	36	18	of	of	IN
cord-313312-h607itv2	36	19	a	a	DT
cord-313312-h607itv2	36	20	natural	natural	JJ
cord-313312-h607itv2	36	21	infection	infection	NN
cord-313312-h607itv2	36	22	,	,	,
cord-313312-h607itv2	36	23	although	although	IN
cord-313312-h607itv2	36	24	antibody	antibody	NN
cord-313312-h607itv2	36	25	titers	titer	NNS
cord-313312-h607itv2	36	26	induced	induce	VBN
cord-313312-h607itv2	36	27	are	be	VBP
cord-313312-h607itv2	36	28	often	often	RB
cord-313312-h607itv2	36	29	lower	low	JJR
cord-313312-h607itv2	36	30	[	[	-LRB-
cord-313312-h607itv2	36	31	32	32	CD
cord-313312-h607itv2	36	32	,	,	,
cord-313312-h607itv2	36	33	33	33	CD
cord-313312-h607itv2	36	34	]	]	-RRB-
cord-313312-h607itv2	36	35	.	.	.
cord-313312-h607itv2	37	1	Investigators	investigator	NNS
cord-313312-h607itv2	37	2	have	have	VBP
cord-313312-h607itv2	37	3	demonstrated	demonstrate	VBN
cord-313312-h607itv2	37	4	that	that	IN
cord-313312-h607itv2	37	5	this	this	DT
cord-313312-h607itv2	37	6	protection	protection	NN
cord-313312-h607itv2	37	7	is	be	VBZ
cord-313312-h607itv2	37	8	highly	highly	RB
cord-313312-h607itv2	37	9	robust	robust	JJ
cord-313312-h607itv2	37	10	,	,	,
cord-313312-h607itv2	37	11	and	and	CC
cord-313312-h607itv2	37	12	could	could	MD
cord-313312-h607itv2	37	13	last	last	VB
cord-313312-h607itv2	37	14	for	for	IN
cord-313312-h607itv2	37	15	as	as	RB
cord-313312-h607itv2	37	16	long	long	JJ
cord-313312-h607itv2	37	17	as	as	IN
cord-313312-h607itv2	37	18	20	20	CD
cord-313312-h607itv2	37	19	years	year	NNS
cord-313312-h607itv2	37	20	after	after	IN
cord-313312-h607itv2	37	21	vaccine	vaccine	NN
cord-313312-h607itv2	37	22	administration	administration	NN
cord-313312-h607itv2	37	23	[	[	-LRB-
cord-313312-h607itv2	37	24	34	34	CD
cord-313312-h607itv2	37	25	]	]	-RRB-
cord-313312-h607itv2	37	26	.	.	.
cord-313312-h607itv2	38	1	Its	-PRON-	PRP$
cord-313312-h607itv2	38	2	excellent	excellent	JJ
cord-313312-h607itv2	38	3	safety	safety	NN
cord-313312-h607itv2	38	4	profile	profile	NN
cord-313312-h607itv2	38	5	,	,	,
cord-313312-h607itv2	38	6	highly	highly	RB
cord-313312-h607itv2	38	7	immunogenic	immunogenic	JJ
cord-313312-h607itv2	38	8	nature	nature	NN
cord-313312-h607itv2	38	9	,	,	,
cord-313312-h607itv2	38	10	and	and	CC
cord-313312-h607itv2	38	11	low	low	JJ
cord-313312-h607itv2	38	12	possibility	possibility	NN
cord-313312-h607itv2	38	13	of	of	IN
cord-313312-h607itv2	38	14	reversion	reversion	NN
cord-313312-h607itv2	38	15	to	to	IN
cord-313312-h607itv2	38	16	virulence	virulence	NN
cord-313312-h607itv2	38	17	has	have	VBZ
cord-313312-h607itv2	38	18	also	also	RB
cord-313312-h607itv2	38	19	placed	place	VBN
cord-313312-h607itv2	38	20	it	-PRON-	PRP
cord-313312-h607itv2	38	21	as	as	IN
cord-313312-h607itv2	38	22	a	a	DT
cord-313312-h607itv2	38	23	promising	promising	JJ
cord-313312-h607itv2	38	24	candidate	candidate	NN
cord-313312-h607itv2	38	25	for	for	IN
cord-313312-h607itv2	38	26	use	use	NN
cord-313312-h607itv2	38	27	as	as	IN
cord-313312-h607itv2	38	28	a	a	DT
cord-313312-h607itv2	38	29	viral	viral	JJ
cord-313312-h607itv2	38	30	vector	vector	NN
cord-313312-h607itv2	38	31	to	to	TO
cord-313312-h607itv2	38	32	deliver	deliver	VB
cord-313312-h607itv2	38	33	heterologous	heterologous	JJ
cord-313312-h607itv2	38	34	antigens	antigen	NNS
cord-313312-h607itv2	38	35	[	[	-LRB-
cord-313312-h607itv2	38	36	35	35	CD
cord-313312-h607itv2	38	37	]	]	-RRB-
cord-313312-h607itv2	38	38	.	.	.
cord-313312-h607itv2	39	1	Some	some	DT
cord-313312-h607itv2	39	2	of	of	IN
cord-313312-h607itv2	39	3	the	the	DT
cord-313312-h607itv2	39	4	first	first	JJ
cord-313312-h607itv2	39	5	evidence	evidence	NN
cord-313312-h607itv2	39	6	that	that	WDT
cord-313312-h607itv2	39	7	describes	describe	VBZ
cord-313312-h607itv2	39	8	the	the	DT
cord-313312-h607itv2	39	9	role	role	NN
cord-313312-h607itv2	39	10	of	of	IN
cord-313312-h607itv2	39	11	pre	pre	JJ
cord-313312-h607itv2	39	12	-	-	JJ
cord-313312-h607itv2	39	13	existing	existing	JJ
cord-313312-h607itv2	39	14	immunity	immunity	NN
cord-313312-h607itv2	39	15	on	on	IN
cord-313312-h607itv2	39	16	live	live	JJ
cord-313312-h607itv2	39	17	vaccines	vaccine	NNS
cord-313312-h607itv2	39	18	comes	come	VBZ
cord-313312-h607itv2	39	19	from	from	IN
cord-313312-h607itv2	39	20	the	the	DT
cord-313312-h607itv2	39	21	measles	measle	NNS
cord-313312-h607itv2	39	22	vaccine	vaccine	NN
cord-313312-h607itv2	39	23	.	.	.
cord-313312-h607itv2	40	1	The	the	DT
cord-313312-h607itv2	40	2	efficacy	efficacy	NN
cord-313312-h607itv2	40	3	of	of	IN
cord-313312-h607itv2	40	4	live	live	JJ
cord-313312-h607itv2	40	5	MV	MV	NNP
cord-313312-h607itv2	40	6	was	be	VBD
cord-313312-h607itv2	40	7	found	find	VBN
cord-313312-h607itv2	40	8	to	to	TO
cord-313312-h607itv2	40	9	be	be	VB
cord-313312-h607itv2	40	10	often	often	RB
cord-313312-h607itv2	40	11	hampered	hamper	VBN
cord-313312-h607itv2	40	12	by	by	IN
cord-313312-h607itv2	40	13	pre	pre	JJ
cord-313312-h607itv2	40	14	-	-	JJ
cord-313312-h607itv2	40	15	existing	existing	JJ
cord-313312-h607itv2	40	16	immunity	immunity	NN
cord-313312-h607itv2	40	17	at	at	IN
cord-313312-h607itv2	40	18	the	the	DT
cord-313312-h607itv2	40	19	time	time	NN
cord-313312-h607itv2	40	20	of	of	IN
cord-313312-h607itv2	40	21	vaccination	vaccination	NN
cord-313312-h607itv2	40	22	,	,	,
cord-313312-h607itv2	40	23	and	and	CC
cord-313312-h607itv2	40	24	this	this	DT
cord-313312-h607itv2	40	25	effect	effect	NN
cord-313312-h607itv2	40	26	is	be	VBZ
cord-313312-h607itv2	40	27	best	well	RBS
cord-313312-h607itv2	40	28	illustrated	illustrate	VBN
cord-313312-h607itv2	40	29	in	in	IN
cord-313312-h607itv2	40	30	infants	infant	NNS
cord-313312-h607itv2	40	31	who	who	WP
cord-313312-h607itv2	40	32	are	be	VBP
cord-313312-h607itv2	40	33	born	bear	VBN
cord-313312-h607itv2	40	34	to	to	IN
cord-313312-h607itv2	40	35	measles	measles	NN
cord-313312-h607itv2	40	36	-	-	HYPH
cord-313312-h607itv2	40	37	immune	immune	JJ
cord-313312-h607itv2	40	38	mothers	mother	NNS
cord-313312-h607itv2	40	39	.	.	.
cord-313312-h607itv2	41	1	During	during	IN
cord-313312-h607itv2	41	2	gestation	gestation	NN
cord-313312-h607itv2	41	3	,	,	,
cord-313312-h607itv2	41	4	infants	infant	NNS
cord-313312-h607itv2	41	5	acquire	acquire	VBP
cord-313312-h607itv2	41	6	protective	protective	JJ
cord-313312-h607itv2	41	7	antibodies	antibody	NNS
cord-313312-h607itv2	41	8	as	as	IN
cord-313312-h607itv2	41	9	a	a	DT
cord-313312-h607itv2	41	10	result	result	NN
cord-313312-h607itv2	41	11	of	of	IN
cord-313312-h607itv2	41	12	transplacental	transplacental	NNP
cord-313312-h607itv2	41	13	transfer	transfer	NN
cord-313312-h607itv2	41	14	of	of	IN
cord-313312-h607itv2	41	15	maternal	maternal	JJ
cord-313312-h607itv2	41	16	IgG	IgG	NNP
cord-313312-h607itv2	41	17	antibodies	antibody	NNS
cord-313312-h607itv2	41	18	[	[	-LRB-
cord-313312-h607itv2	41	19	36	36	CD
cord-313312-h607itv2	41	20	]	]	-RRB-
cord-313312-h607itv2	41	21	.	.	.
cord-313312-h607itv2	42	1	These	these	DT
cord-313312-h607itv2	42	2	antibodies	antibody	NNS
cord-313312-h607itv2	42	3	,	,	,
cord-313312-h607itv2	42	4	while	while	IN
cord-313312-h607itv2	42	5	protective	protective	JJ
cord-313312-h607itv2	42	6	against	against	IN
cord-313312-h607itv2	42	7	infection	infection	NN
cord-313312-h607itv2	42	8	,	,	,
cord-313312-h607itv2	42	9	can	can	MD
cord-313312-h607itv2	42	10	also	also	RB
cord-313312-h607itv2	42	11	suppress	suppress	VB
cord-313312-h607itv2	42	12	infant	infant	NN
cord-313312-h607itv2	42	13	responses	response	NNS
cord-313312-h607itv2	42	14	to	to	IN
cord-313312-h607itv2	42	15	immunization	immunization	NN
cord-313312-h607itv2	42	16	.	.	.
cord-313312-h607itv2	43	1	Indeed	indeed	RB
cord-313312-h607itv2	43	2	,	,	,
cord-313312-h607itv2	43	3	studies	study	NNS
cord-313312-h607itv2	43	4	have	have	VBP
cord-313312-h607itv2	43	5	shown	show	VBN
cord-313312-h607itv2	43	6	that	that	IN
cord-313312-h607itv2	43	7	vaccinating	vaccinate	VBG
cord-313312-h607itv2	43	8	infants	infant	NNS
cord-313312-h607itv2	43	9	born	bear	VBN
cord-313312-h607itv2	43	10	to	to	IN
cord-313312-h607itv2	43	11	measles	measles	NN
cord-313312-h607itv2	43	12	-	-	HYPH
cord-313312-h607itv2	43	13	immune	immune	JJ
cord-313312-h607itv2	43	14	mothers	mother	NNS
cord-313312-h607itv2	43	15	before	before	IN
cord-313312-h607itv2	43	16	or	or	CC
cord-313312-h607itv2	43	17	at	at	IN
cord-313312-h607itv2	43	18	the	the	DT
cord-313312-h607itv2	43	19	age	age	NN
cord-313312-h607itv2	43	20	of	of	IN
cord-313312-h607itv2	43	21	six	six	CD
cord-313312-h607itv2	43	22	months	month	NNS
cord-313312-h607itv2	43	23	often	often	RB
cord-313312-h607itv2	43	24	results	result	VBZ
cord-313312-h607itv2	43	25	in	in	IN
cord-313312-h607itv2	43	26	seroconversion	seroconversion	NN
cord-313312-h607itv2	43	27	failure	failure	NN
cord-313312-h607itv2	43	28	[	[	-LRB-
cord-313312-h607itv2	43	29	37	37	CD
cord-313312-h607itv2	43	30	,	,	,
cord-313312-h607itv2	43	31	38	38	CD
cord-313312-h607itv2	43	32	]	]	-RRB-
cord-313312-h607itv2	43	33	.	.	.
cord-313312-h607itv2	44	1	By	by	IN
cord-313312-h607itv2	44	2	contrast	contrast	NN
cord-313312-h607itv2	44	3	,	,	,
cord-313312-h607itv2	44	4	immunization	immunization	NN
cord-313312-h607itv2	44	5	campaigns	campaign	NNS
cord-313312-h607itv2	44	6	with	with	IN
cord-313312-h607itv2	44	7	MV	MV	NNP
cord-313312-h607itv2	44	8	between	between	IN
cord-313312-h607itv2	44	9	9	9	CD
cord-313312-h607itv2	44	10	to	to	TO
cord-313312-h607itv2	44	11	12	12	CD
cord-313312-h607itv2	44	12	months	month	NNS
cord-313312-h607itv2	44	13	of	of	IN
cord-313312-h607itv2	44	14	age	age	NN
cord-313312-h607itv2	44	15	are	be	VBP
cord-313312-h607itv2	44	16	relatively	relatively	RB
cord-313312-h607itv2	44	17	successful	successful	JJ
cord-313312-h607itv2	44	18	[	[	-LRB-
cord-313312-h607itv2	44	19	39	39	CD
cord-313312-h607itv2	44	20	,	,	,
cord-313312-h607itv2	44	21	40	40	CD
cord-313312-h607itv2	44	22	]	]	-RRB-
cord-313312-h607itv2	44	23	.	.	.
cord-313312-h607itv2	45	1	This	this	DT
cord-313312-h607itv2	45	2	is	be	VBZ
cord-313312-h607itv2	45	3	likely	likely	RB
cord-313312-h607itv2	45	4	explained	explain	VBN
cord-313312-h607itv2	45	5	by	by	IN
cord-313312-h607itv2	45	6	waning	wane	VBG
cord-313312-h607itv2	45	7	maternal	maternal	JJ
cord-313312-h607itv2	45	8	antibody	antibody	NN
cord-313312-h607itv2	45	9	levels	level	NNS
cord-313312-h607itv2	45	10	over	over	IN
cord-313312-h607itv2	45	11	the	the	DT
cord-313312-h607itv2	45	12	period	period	NN
cord-313312-h607itv2	45	13	of	of	IN
cord-313312-h607itv2	45	14	6	6	CD
cord-313312-h607itv2	45	15	to	to	TO
cord-313312-h607itv2	45	16	12	12	CD
cord-313312-h607itv2	45	17	months	month	NNS
cord-313312-h607itv2	45	18	,	,	,
cord-313312-h607itv2	45	19	where	where	WRB
cord-313312-h607itv2	45	20	antibody	antibody	NN
cord-313312-h607itv2	45	21	titers	titer	NNS
cord-313312-h607itv2	45	22	fall	fall	VBP
cord-313312-h607itv2	45	23	below	below	IN
cord-313312-h607itv2	45	24	the	the	DT
cord-313312-h607itv2	45	25	inhibitory	inhibitory	JJ
cord-313312-h607itv2	45	26	threshold	threshold	NN
cord-313312-h607itv2	45	27	required	require	VBN
cord-313312-h607itv2	45	28	for	for	IN
cord-313312-h607itv2	45	29	successful	successful	JJ
cord-313312-h607itv2	45	30	vaccination	vaccination	NN
cord-313312-h607itv2	45	31	[	[	-LRB-
cord-313312-h607itv2	45	32	41	41	CD
cord-313312-h607itv2	45	33	]	]	-RRB-
cord-313312-h607itv2	45	34	.	.	.
cord-313312-h607itv2	46	1	Moreover	moreover	RB
cord-313312-h607itv2	46	2	,	,	,
cord-313312-h607itv2	46	3	the	the	DT
cord-313312-h607itv2	46	4	claims	claim	NNS
cord-313312-h607itv2	46	5	that	that	WDT
cord-313312-h607itv2	46	6	pre	pre	JJ
cord-313312-h607itv2	46	7	-	-	JJ
cord-313312-h607itv2	46	8	existing	existing	JJ
cord-313312-h607itv2	46	9	antibody	antibody	NN
cord-313312-h607itv2	46	10	titers	titer	NNS
cord-313312-h607itv2	46	11	can	can	MD
cord-313312-h607itv2	46	12	impact	impact	VB
cord-313312-h607itv2	46	13	MV	MV	NNP
cord-313312-h607itv2	46	14	efficacy	efficacy	NN
cord-313312-h607itv2	46	15	are	be	VBP
cord-313312-h607itv2	46	16	further	further	RB
cord-313312-h607itv2	46	17	supported	support	VBN
cord-313312-h607itv2	46	18	by	by	IN
cord-313312-h607itv2	46	19	animal	animal	NN
cord-313312-h607itv2	46	20	studies	study	NNS
cord-313312-h607itv2	46	21	.	.	.
cord-313312-h607itv2	47	1	For	for	IN
cord-313312-h607itv2	47	2	instance	instance	NN
cord-313312-h607itv2	47	3	,	,	,
cord-313312-h607itv2	47	4	following	follow	VBG
cord-313312-h607itv2	47	5	the	the	DT
cord-313312-h607itv2	47	6	intravenous	intravenous	JJ
cord-313312-h607itv2	47	7	transfer	transfer	NN
cord-313312-h607itv2	47	8	of	of	IN
cord-313312-h607itv2	47	9	varying	vary	VBG
cord-313312-h607itv2	47	10	titers	titer	NNS
cord-313312-h607itv2	47	11	of	of	IN
cord-313312-h607itv2	47	12	MV	MV	NNP
cord-313312-h607itv2	47	13	neutralizing	neutralize	VBG
cord-313312-h607itv2	47	14	antibodies	antibody	NNS
cord-313312-h607itv2	47	15	,	,	,
cord-313312-h607itv2	47	16	immunization	immunization	NN
cord-313312-h607itv2	47	17	of	of	IN
cord-313312-h607itv2	47	18	mice	mouse	NNS
cord-313312-h607itv2	47	19	with	with	IN
cord-313312-h607itv2	47	20	a	a	DT
cord-313312-h607itv2	47	21	recombinant	recombinant	JJ
cord-313312-h607itv2	47	22	measles	measle	NNS
cord-313312-h607itv2	47	23	vaccine	vaccine	NN
cord-313312-h607itv2	47	24	(	(	-LRB-
cord-313312-h607itv2	47	25	rMV	rMV	NNP
cord-313312-h607itv2	47	26	)	)	-RRB-
cord-313312-h607itv2	47	27	expressing	express	VBG
cord-313312-h607itv2	48	1	Simian	simian	JJ
cord-313312-h607itv2	48	2	Immunodeficiency	Immunodeficiency	NNP
cord-313312-h607itv2	48	3	Virus	Virus	NNP
cord-313312-h607itv2	48	4	(	(	-LRB-
cord-313312-h607itv2	48	5	SIV	SIV	NNP
cord-313312-h607itv2	48	6	)	)	-RRB-
cord-313312-h607itv2	48	7	gag	gag	NN
cord-313312-h607itv2	48	8	protein	protein	NN
cord-313312-h607itv2	48	9	was	be	VBD
cord-313312-h607itv2	48	10	significantly	significantly	RB
cord-313312-h607itv2	48	11	inhibited	inhibit	VBN
cord-313312-h607itv2	48	12	when	when	WRB
cord-313312-h607itv2	48	13	pre	pre	JJ
cord-313312-h607itv2	48	14	-	-	JJ
cord-313312-h607itv2	48	15	existing	existing	JJ
cord-313312-h607itv2	48	16	antibody	antibody	NN
cord-313312-h607itv2	48	17	titers	titer	NNS
cord-313312-h607itv2	48	18	were	be	VBD
cord-313312-h607itv2	48	19	above	above	IN
cord-313312-h607itv2	48	20	500mIU	500miu	CD
cord-313312-h607itv2	48	21	/	/	SYM
cord-313312-h607itv2	48	22	mL	ml	NN
cord-313312-h607itv2	48	23	of	of	IN
cord-313312-h607itv2	48	24	serum	serum	NN
cord-313312-h607itv2	48	25	[	[	-LRB-
cord-313312-h607itv2	48	26	35	35	CD
cord-313312-h607itv2	48	27	]	]	-RRB-
cord-313312-h607itv2	48	28	.	.	.
cord-313312-h607itv2	49	1	Likewise	likewise	RB
cord-313312-h607itv2	49	2	,	,	,
cord-313312-h607itv2	49	3	investigations	investigation	NNS
cord-313312-h607itv2	49	4	in	in	IN
cord-313312-h607itv2	49	5	cynomolgus	cynomolgus	JJ
cord-313312-h607itv2	49	6	macaques	macaque	NNS
cord-313312-h607itv2	49	7	by	by	IN
cord-313312-h607itv2	49	8	van	van	NNP
cord-313312-h607itv2	49	9	Binnendijk	Binnendijk	NNP
cord-313312-h607itv2	49	10	et	et	NNP
cord-313312-h607itv2	49	11	al	al	NNP
cord-313312-h607itv2	49	12	.	.	NNP
cord-313312-h607itv2	49	13	revealed	reveal	VBD
cord-313312-h607itv2	49	14	that	that	IN
cord-313312-h607itv2	49	15	pre	pre	JJ
cord-313312-h607itv2	49	16	-	-	JJ
cord-313312-h607itv2	49	17	existing	existing	JJ
cord-313312-h607itv2	49	18	antibody	antibody	NN
cord-313312-h607itv2	49	19	titers	titer	NNS
cord-313312-h607itv2	49	20	as	as	RB
cord-313312-h607itv2	49	21	low	low	JJ
cord-313312-h607itv2	49	22	as	as	IN
cord-313312-h607itv2	49	23	0.1IU	0.1iu	CD
cord-313312-h607itv2	50	1	/mL	/mL	NFP
cord-313312-h607itv2	50	2	abrogated	abrogate	VBD
cord-313312-h607itv2	50	3	the	the	DT
cord-313312-h607itv2	50	4	development	development	NN
cord-313312-h607itv2	50	5	of	of	IN
cord-313312-h607itv2	50	6	antibodies	antibody	NNS
cord-313312-h607itv2	50	7	following	follow	VBG
cord-313312-h607itv2	50	8	vaccination	vaccination	NN
cord-313312-h607itv2	50	9	with	with	IN
cord-313312-h607itv2	50	10	MV	MV	NNP
cord-313312-h607itv2	50	11	or	or	CC
cord-313312-h607itv2	50	12	a	a	DT
cord-313312-h607itv2	50	13	recombinant	recombinant	JJ
cord-313312-h607itv2	50	14	vaccinia	vaccinia	NN
cord-313312-h607itv2	50	15	virus	virus	NN
cord-313312-h607itv2	50	16	vector	vector	NN
cord-313312-h607itv2	50	17	expressing	express	VBG
cord-313312-h607itv2	50	18	measles	measles	NN
cord-313312-h607itv2	50	19	antigens	antigen	NNS
cord-313312-h607itv2	50	20	[	[	-LRB-
cord-313312-h607itv2	50	21	42	42	CD
cord-313312-h607itv2	50	22	]	]	-RRB-
cord-313312-h607itv2	50	23	.	.	.
cord-313312-h607itv2	51	1	Interestingly	interestingly	RB
cord-313312-h607itv2	51	2	,	,	,
cord-313312-h607itv2	51	3	while	while	IN
cord-313312-h607itv2	51	4	antibody	antibody	NN
cord-313312-h607itv2	51	5	induction	induction	NN
cord-313312-h607itv2	51	6	by	by	IN
cord-313312-h607itv2	51	7	MV	MV	NNP
cord-313312-h607itv2	51	8	is	be	VBZ
cord-313312-h607itv2	51	9	negatively	negatively	RB
cord-313312-h607itv2	51	10	impacted	impact	VBN
cord-313312-h607itv2	51	11	by	by	IN
cord-313312-h607itv2	51	12	pre	pre	JJ
cord-313312-h607itv2	51	13	-	-	JJ
cord-313312-h607itv2	51	14	existing	existing	JJ
cord-313312-h607itv2	51	15	immunity	immunity	NN
cord-313312-h607itv2	51	16	,	,	,
cord-313312-h607itv2	51	17	the	the	DT
cord-313312-h607itv2	51	18	effect	effect	NN
cord-313312-h607itv2	51	19	on	on	IN
cord-313312-h607itv2	51	20	cellular	cellular	JJ
cord-313312-h607itv2	51	21	responses	response	NNS
cord-313312-h607itv2	51	22	seem	seem	VBP
cord-313312-h607itv2	51	23	unaffected	unaffected	JJ
cord-313312-h607itv2	51	24	.	.	.
cord-313312-h607itv2	52	1	For	for	IN
cord-313312-h607itv2	52	2	example	example	NN
cord-313312-h607itv2	52	3	,	,	,
cord-313312-h607itv2	52	4	infants	infant	NNS
cord-313312-h607itv2	52	5	vaccinated	vaccinate	VBN
cord-313312-h607itv2	52	6	with	with	IN
cord-313312-h607itv2	52	7	MV	MV	NNP
cord-313312-h607itv2	52	8	at	at	IN
cord-313312-h607itv2	52	9	age	age	NN
cord-313312-h607itv2	52	10	6	6	CD
cord-313312-h607itv2	52	11	or	or	CC
cord-313312-h607itv2	52	12	9	9	CD
cord-313312-h607itv2	52	13	months	month	NNS
cord-313312-h607itv2	52	14	followed	follow	VBN
cord-313312-h607itv2	52	15	by	by	IN
cord-313312-h607itv2	52	16	the	the	DT
cord-313312-h607itv2	52	17	measles	measles	NN
cord-313312-h607itv2	52	18	-	-	HYPH
cord-313312-h607itv2	52	19	mumps	mumps	NN
cord-313312-h607itv2	52	20	-	-	HYPH
cord-313312-h607itv2	52	21	rubella	rubella	NN
cord-313312-h607itv2	52	22	(	(	-LRB-
cord-313312-h607itv2	52	23	MMR	MMR	NNP
cord-313312-h607itv2	52	24	)	)	-RRB-
cord-313312-h607itv2	52	25	vaccine	vaccine	NN
cord-313312-h607itv2	52	26	at	at	IN
cord-313312-h607itv2	52	27	12	12	CD
cord-313312-h607itv2	52	28	months	month	NNS
cord-313312-h607itv2	52	29	generated	generate	VBN
cord-313312-h607itv2	52	30	equivalent	equivalent	JJ
cord-313312-h607itv2	52	31	T	t	NN
cord-313312-h607itv2	52	32	-	-	HYPH
cord-313312-h607itv2	52	33	cell	cell	NN
cord-313312-h607itv2	52	34	responses	response	NNS
cord-313312-h607itv2	52	35	to	to	TO
cord-313312-h607itv2	52	36	control	control	VB
cord-313312-h607itv2	52	37	infants	infant	NNS
cord-313312-h607itv2	52	38	given	give	VBN
cord-313312-h607itv2	52	39	only	only	RB
cord-313312-h607itv2	52	40	MMR	MMR	NNP
cord-313312-h607itv2	52	41	at	at	IN
cord-313312-h607itv2	52	42	age	age	NN
cord-313312-h607itv2	52	43	12	12	CD
cord-313312-h607itv2	52	44	months	month	NNS
cord-313312-h607itv2	52	45	[	[	-LRB-
cord-313312-h607itv2	52	46	43	43	CD
cord-313312-h607itv2	52	47	]	]	-RRB-
cord-313312-h607itv2	52	48	.	.	.
cord-313312-h607itv2	53	1	Thus	thus	RB
cord-313312-h607itv2	53	2	,	,	,
cord-313312-h607itv2	53	3	experimental	experimental	JJ
cord-313312-h607itv2	53	4	models	model	NNS
cord-313312-h607itv2	53	5	and	and	CC
cord-313312-h607itv2	53	6	clinical	clinical	JJ
cord-313312-h607itv2	53	7	data	data	NN
cord-313312-h607itv2	53	8	support	support	NN
cord-313312-h607itv2	53	9	that	that	IN
cord-313312-h607itv2	53	10	the	the	DT
cord-313312-h607itv2	53	11	inhibition	inhibition	NN
cord-313312-h607itv2	53	12	of	of	IN
cord-313312-h607itv2	53	13	MV	MV	NNP
cord-313312-h607itv2	53	14	vaccination	vaccination	NN
cord-313312-h607itv2	53	15	in	in	IN
cord-313312-h607itv2	53	16	neonates	neonate	NNS
cord-313312-h607itv2	53	17	is	be	VBZ
cord-313312-h607itv2	53	18	more	more	RBR
cord-313312-h607itv2	53	19	likely	likely	JJ
cord-313312-h607itv2	53	20	due	due	IN
cord-313312-h607itv2	53	21	to	to	IN
cord-313312-h607itv2	53	22	interference	interference	NN
cord-313312-h607itv2	53	23	from	from	IN
cord-313312-h607itv2	53	24	maternal	maternal	JJ
cord-313312-h607itv2	53	25	antibodies	antibody	NNS
cord-313312-h607itv2	53	26	rather	rather	RB
cord-313312-h607itv2	53	27	than	than	IN
cord-313312-h607itv2	53	28	the	the	DT
cord-313312-h607itv2	53	29	immaturity	immaturity	NN
cord-313312-h607itv2	53	30	of	of	IN
cord-313312-h607itv2	53	31	the	the	DT
cord-313312-h607itv2	53	32	neonatal	neonatal	JJ
cord-313312-h607itv2	53	33	system	system	NN
cord-313312-h607itv2	53	34	.	.	.
cord-313312-h607itv2	54	1	Adenoviruses	adenovirus	NNS
cord-313312-h607itv2	54	2	(	(	-LRB-
cord-313312-h607itv2	54	3	AdV	AdV	NNP
cord-313312-h607itv2	54	4	)	)	-RRB-
cord-313312-h607itv2	54	5	and	and	CC
cord-313312-h607itv2	54	6	adeno	adeno	NN
cord-313312-h607itv2	54	7	-	-	HYPH
cord-313312-h607itv2	54	8	associated	associate	VBN
cord-313312-h607itv2	54	9	viruses	virus	NNS
cord-313312-h607itv2	54	10	have	have	VBP
cord-313312-h607itv2	54	11	been	be	VBN
cord-313312-h607itv2	54	12	widely	widely	RB
cord-313312-h607itv2	54	13	studied	study	VBN
cord-313312-h607itv2	54	14	as	as	IN
cord-313312-h607itv2	54	15	a	a	DT
cord-313312-h607itv2	54	16	potential	potential	JJ
cord-313312-h607itv2	54	17	viral	viral	JJ
cord-313312-h607itv2	54	18	vector	vector	NN
cord-313312-h607itv2	54	19	for	for	IN
cord-313312-h607itv2	54	20	cancer	cancer	NN
cord-313312-h607itv2	54	21	gene	gene	NN
cord-313312-h607itv2	54	22	therapy	therapy	NN
cord-313312-h607itv2	54	23	and	and	CC
cord-313312-h607itv2	54	24	infectious	infectious	JJ
cord-313312-h607itv2	54	25	diseases	disease	NNS
cord-313312-h607itv2	54	26	.	.	.
cord-313312-h607itv2	55	1	This	this	DT
cord-313312-h607itv2	55	2	double	double	RB
cord-313312-h607itv2	55	3	-	-	HYPH
cord-313312-h607itv2	55	4	stranded	strand	VBN
cord-313312-h607itv2	55	5	DNA	dna	NN
cord-313312-h607itv2	55	6	virus	virus	NN
cord-313312-h607itv2	55	7	holds	hold	VBZ
cord-313312-h607itv2	55	8	several	several	JJ
cord-313312-h607itv2	55	9	advantages	advantage	NNS
cord-313312-h607itv2	55	10	as	as	IN
cord-313312-h607itv2	55	11	a	a	DT
cord-313312-h607itv2	55	12	vector	vector	NN
cord-313312-h607itv2	55	13	,	,	,
cord-313312-h607itv2	55	14	including	include	VBG
cord-313312-h607itv2	55	15	but	but	CC
cord-313312-h607itv2	55	16	not	not	RB
cord-313312-h607itv2	55	17	limited	limited	JJ
cord-313312-h607itv2	55	18	to	to	IN
cord-313312-h607itv2	55	19	the	the	DT
cord-313312-h607itv2	55	20	ability	ability	NN
cord-313312-h607itv2	55	21	to	to	TO
cord-313312-h607itv2	55	22	induce	induce	VB
cord-313312-h607itv2	55	23	robust	robust	JJ
cord-313312-h607itv2	55	24	cellular	cellular	JJ
cord-313312-h607itv2	55	25	and	and	CC
cord-313312-h607itv2	55	26	humoral	humoral	JJ
cord-313312-h607itv2	55	27	responses	response	NNS
cord-313312-h607itv2	55	28	,	,	,
cord-313312-h607itv2	55	29	high	high	JJ
cord-313312-h607itv2	55	30	expression	expression	NN
cord-313312-h607itv2	55	31	of	of	IN
cord-313312-h607itv2	55	32	transgenes	transgene	NNS
cord-313312-h607itv2	55	33	,	,	,
cord-313312-h607itv2	55	34	favorable	favorable	JJ
cord-313312-h607itv2	55	35	safety	safety	NN
cord-313312-h607itv2	55	36	profiles	profile	NNS
cord-313312-h607itv2	55	37	,	,	,
cord-313312-h607itv2	55	38	and	and	CC
cord-313312-h607itv2	55	39	no	no	DT
cord-313312-h607itv2	55	40	risk	risk	NN
cord-313312-h607itv2	55	41	of	of	IN
cord-313312-h607itv2	55	42	integration	integration	NN
cord-313312-h607itv2	55	43	into	into	IN
cord-313312-h607itv2	55	44	the	the	DT
cord-313312-h607itv2	55	45	host	host	NN
cord-313312-h607itv2	55	46	genome	genome	NN
cord-313312-h607itv2	55	47	.	.	.
cord-313312-h607itv2	56	1	The	the	DT
cord-313312-h607itv2	56	2	most	most	RBS
cord-313312-h607itv2	56	3	commonly	commonly	RB
cord-313312-h607itv2	56	4	used	use	VBN
cord-313312-h607itv2	56	5	adenoviral	adenoviral	JJ
cord-313312-h607itv2	56	6	vector	vector	NN
cord-313312-h607itv2	56	7	is	be	VBZ
cord-313312-h607itv2	56	8	AdV	adv	NN
cord-313312-h607itv2	56	9	serotype	serotype	NN
cord-313312-h607itv2	56	10	5	5	CD
cord-313312-h607itv2	56	11	(	(	-LRB-
cord-313312-h607itv2	56	12	Ad5	Ad5	NNP
cord-313312-h607itv2	56	13	)	)	-RRB-
cord-313312-h607itv2	56	14	and	and	CC
cord-313312-h607itv2	56	15	has	have	VBZ
cord-313312-h607itv2	56	16	been	be	VBN
cord-313312-h607itv2	56	17	tested	test	VBN
cord-313312-h607itv2	56	18	in	in	IN
cord-313312-h607itv2	56	19	more	more	JJR
cord-313312-h607itv2	56	20	than	than	IN
cord-313312-h607itv2	56	21	400	400	CD
cord-313312-h607itv2	56	22	gene	gene	NN
cord-313312-h607itv2	56	23	therapy	therapy	NN
cord-313312-h607itv2	56	24	trials	trial	NNS
cord-313312-h607itv2	56	25	.	.	.
cord-313312-h607itv2	57	1	However	however	RB
cord-313312-h607itv2	57	2	,	,	,
cord-313312-h607itv2	57	3	the	the	DT
cord-313312-h607itv2	57	4	large	large	JJ
cord-313312-h607itv2	57	5	majority	majority	NN
cord-313312-h607itv2	57	6	of	of	IN
cord-313312-h607itv2	57	7	the	the	DT
cord-313312-h607itv2	57	8	human	human	JJ
cord-313312-h607itv2	57	9	population	population	NN
cord-313312-h607itv2	57	10	having	have	VBG
cord-313312-h607itv2	57	11	pre	pre	JJ
cord-313312-h607itv2	57	12	-	-	JJ
cord-313312-h607itv2	57	13	existing	existing	JJ
cord-313312-h607itv2	57	14	immunity	immunity	NN
cord-313312-h607itv2	57	15	to	to	IN
cord-313312-h607itv2	57	16	AdV	adv	NN
cord-313312-h607itv2	57	17	limits	limit	VBZ
cord-313312-h607itv2	57	18	its	-PRON-	PRP$
cord-313312-h607itv2	57	19	widespread	widespread	JJ
cord-313312-h607itv2	57	20	use	use	NN
cord-313312-h607itv2	57	21	in	in	IN
cord-313312-h607itv2	57	22	the	the	DT
cord-313312-h607itv2	57	23	clinics	clinic	NNS
cord-313312-h607itv2	57	24	.	.	.
cord-313312-h607itv2	58	1	Indeed	indeed	RB
cord-313312-h607itv2	58	2	,	,	,
cord-313312-h607itv2	58	3	a	a	DT
cord-313312-h607itv2	58	4	recent	recent	JJ
cord-313312-h607itv2	58	5	international	international	JJ
cord-313312-h607itv2	58	6	cross	cross	JJ
cord-313312-h607itv2	58	7	-	-	JJ
cord-313312-h607itv2	58	8	sectional	sectional	JJ
cord-313312-h607itv2	58	9	serological	serological	JJ
cord-313312-h607itv2	58	10	survey	survey	NN
cord-313312-h607itv2	58	11	demonstrated	demonstrate	VBD
cord-313312-h607itv2	58	12	that	that	IN
cord-313312-h607itv2	58	13	greater	great	JJR
cord-313312-h607itv2	58	14	than	than	IN
cord-313312-h607itv2	58	15	80	80	CD
cord-313312-h607itv2	58	16	%	%	NN
cord-313312-h607itv2	58	17	of	of	IN
cord-313312-h607itv2	58	18	the	the	DT
cord-313312-h607itv2	58	19	study	study	NN
cord-313312-h607itv2	58	20	participants	participant	NNS
cord-313312-h607itv2	58	21	possessed	possess	VBD
cord-313312-h607itv2	58	22	neutralizing	neutralize	VBG
cord-313312-h607itv2	58	23	antibodies	antibody	NNS
cord-313312-h607itv2	58	24	against	against	IN
cord-313312-h607itv2	58	25	Ad5	ad5	CD
cord-313312-h607itv2	58	26	[	[	-LRB-
cord-313312-h607itv2	58	27	44	44	CD
cord-313312-h607itv2	58	28	]	]	-RRB-
cord-313312-h607itv2	58	29	.	.	.
cord-313312-h607itv2	59	1	In	in	IN
cord-313312-h607itv2	59	2	a	a	DT
cord-313312-h607itv2	59	3	similar	similar	JJ
cord-313312-h607itv2	59	4	line	line	NN
cord-313312-h607itv2	59	5	of	of	IN
cord-313312-h607itv2	59	6	investigation	investigation	NN
cord-313312-h607itv2	59	7	,	,	,
cord-313312-h607itv2	59	8	Mast	Mast	NNP
cord-313312-h607itv2	59	9	et	et	NNP
cord-313312-h607itv2	59	10	al	al	NNP
cord-313312-h607itv2	59	11	.	.	NNP
cord-313312-h607itv2	59	12	found	find	VBD
cord-313312-h607itv2	59	13	that	that	IN
cord-313312-h607itv2	59	14	85.2	85.2	CD
cord-313312-h607itv2	59	15	%	%	NN
cord-313312-h607itv2	59	16	of	of	IN
cord-313312-h607itv2	59	17	their	-PRON-	PRP$
cord-313312-h607itv2	59	18	study	study	NN
cord-313312-h607itv2	59	19	participants	participant	NNS
cord-313312-h607itv2	59	20	from	from	IN
cord-313312-h607itv2	59	21	the	the	DT
cord-313312-h607itv2	59	22	US	US	NNP
cord-313312-h607itv2	59	23	,	,	,
cord-313312-h607itv2	59	24	Europe	Europe	NNP
cord-313312-h607itv2	59	25	,	,	,
cord-313312-h607itv2	59	26	Thailand	Thailand	NNP
cord-313312-h607itv2	59	27	,	,	,
cord-313312-h607itv2	59	28	Africa	Africa	NNP
cord-313312-h607itv2	59	29	,	,	,
cord-313312-h607itv2	59	30	and	and	CC
cord-313312-h607itv2	59	31	Brazil	Brazil	NNP
cord-313312-h607itv2	59	32	were	be	VBD
cord-313312-h607itv2	59	33	seropositive	seropositive	JJ
cord-313312-h607itv2	59	34	for	for	IN
cord-313312-h607itv2	59	35	anti	anti	JJ
cord-313312-h607itv2	59	36	-	-	JJ
cord-313312-h607itv2	59	37	Ad5	ad5	JJ
cord-313312-h607itv2	59	38	neutralizing	neutralize	VBG
cord-313312-h607itv2	59	39	antibodies	antibody	NNS
cord-313312-h607itv2	59	40	[	[	-LRB-
cord-313312-h607itv2	59	41	45	45	CD
cord-313312-h607itv2	59	42	]	]	-RRB-
cord-313312-h607itv2	59	43	.	.	.
cord-313312-h607itv2	60	1	These	these	DT
cord-313312-h607itv2	60	2	pre	pre	JJ
cord-313312-h607itv2	60	3	-	-	JJ
cord-313312-h607itv2	60	4	existing	existing	JJ
cord-313312-h607itv2	60	5	antibodies	antibody	NNS
cord-313312-h607itv2	60	6	have	have	VBP
cord-313312-h607itv2	60	7	been	be	VBN
cord-313312-h607itv2	60	8	shown	show	VBN
cord-313312-h607itv2	60	9	to	to	TO
cord-313312-h607itv2	60	10	neutralize	neutralize	VB
cord-313312-h607itv2	60	11	the	the	DT
cord-313312-h607itv2	60	12	Ad5	Ad5	NNP
cord-313312-h607itv2	60	13	vectors	vector	NNS
cord-313312-h607itv2	60	14	after	after	IN
cord-313312-h607itv2	60	15	administration	administration	NN
cord-313312-h607itv2	60	16	,	,	,
cord-313312-h607itv2	60	17	thereby	thereby	RB
cord-313312-h607itv2	60	18	lowering	lower	VBG
cord-313312-h607itv2	60	19	their	-PRON-	PRP$
cord-313312-h607itv2	60	20	efficacy	efficacy	NN
cord-313312-h607itv2	60	21	and	and	CC
cord-313312-h607itv2	60	22	transgene	transgene	NN
cord-313312-h607itv2	60	23	expression	expression	NN
cord-313312-h607itv2	60	24	.	.	.
cord-313312-h607itv2	61	1	The	the	DT
cord-313312-h607itv2	61	2	most	most	RBS
cord-313312-h607itv2	61	3	convincing	convincing	JJ
cord-313312-h607itv2	61	4	evidence	evidence	NN
cord-313312-h607itv2	61	5	is	be	VBZ
cord-313312-h607itv2	61	6	from	from	IN
cord-313312-h607itv2	61	7	the	the	DT
cord-313312-h607itv2	61	8	large	large	JJ
cord-313312-h607itv2	61	9	-	-	HYPH
cord-313312-h607itv2	61	10	scale	scale	NN
cord-313312-h607itv2	61	11	clinical	clinical	JJ
cord-313312-h607itv2	61	12	trial	trial	NN
cord-313312-h607itv2	61	13	(	(	-LRB-
cord-313312-h607itv2	61	14	STEP	STEP	NNP
cord-313312-h607itv2	61	15	)	)	-RRB-
cord-313312-h607itv2	61	16	that	that	WDT
cord-313312-h607itv2	61	17	tested	test	VBD
cord-313312-h607itv2	61	18	an	an	DT
cord-313312-h607itv2	61	19	Ad5-based	Ad5-based	NNP
cord-313312-h607itv2	61	20	HIV-1	HIV-1	NNP
cord-313312-h607itv2	61	21	vaccine	vaccine	NN
cord-313312-h607itv2	61	22	,	,	,
cord-313312-h607itv2	61	23	where	where	WRB
cord-313312-h607itv2	61	24	reduced	reduce	VBN
cord-313312-h607itv2	61	25	efficacy	efficacy	NN
cord-313312-h607itv2	61	26	of	of	IN
cord-313312-h607itv2	61	27	Ad5	Ad5	NNP
cord-313312-h607itv2	61	28	was	be	VBD
cord-313312-h607itv2	61	29	found	find	VBN
cord-313312-h607itv2	61	30	to	to	TO
cord-313312-h607itv2	61	31	be	be	VB
cord-313312-h607itv2	61	32	associated	associate	VBN
cord-313312-h607itv2	61	33	with	with	IN
cord-313312-h607itv2	61	34	subjects	subject	NNS
cord-313312-h607itv2	61	35	who	who	WP
cord-313312-h607itv2	61	36	had	have	VBD
cord-313312-h607itv2	61	37	pre	pre	VBN
cord-313312-h607itv2	61	38	-	-	JJ
cord-313312-h607itv2	61	39	existing	existing	JJ
cord-313312-h607itv2	61	40	immunity	immunity	NN
cord-313312-h607itv2	61	41	to	to	IN
cord-313312-h607itv2	61	42	Ad5	Ad5	NNP
cord-313312-h607itv2	61	43	[	[	-LRB-
cord-313312-h607itv2	61	44	46	46	CD
cord-313312-h607itv2	61	45	]	]	-RRB-
cord-313312-h607itv2	61	46	.	.	.
cord-313312-h607itv2	62	1	In	in	IN
cord-313312-h607itv2	62	2	support	support	NN
cord-313312-h607itv2	62	3	of	of	IN
cord-313312-h607itv2	62	4	this	this	DT
cord-313312-h607itv2	62	5	theory	theory	NN
cord-313312-h607itv2	62	6	,	,	,
cord-313312-h607itv2	62	7	the	the	DT
cord-313312-h607itv2	62	8	clinical	clinical	JJ
cord-313312-h607itv2	62	9	trial	trial	NN
cord-313312-h607itv2	62	10	for	for	IN
cord-313312-h607itv2	62	11	the	the	DT
cord-313312-h607itv2	62	12	Ad5-based	Ad5-based	NNP
cord-313312-h607itv2	62	13	Ebola	Ebola	NNP
cord-313312-h607itv2	62	14	vaccine	vaccine	NN
cord-313312-h607itv2	62	15	showed	show	VBD
cord-313312-h607itv2	62	16	that	that	IN
cord-313312-h607itv2	62	17	the	the	DT
cord-313312-h607itv2	62	18	low	low	JJ
cord-313312-h607itv2	62	19	-	-	HYPH
cord-313312-h607itv2	62	20	dose	dose	NN
cord-313312-h607itv2	62	21	vaccine	vaccine	NN
cord-313312-h607itv2	62	22	of	of	IN
cord-313312-h607itv2	62	23	4.0	4.0	CD
cord-313312-h607itv2	62	24	×	×	CD
cord-313312-h607itv2	62	25	10	10	CD
cord-313312-h607itv2	62	26	10	10	CD
cord-313312-h607itv2	62	27	viral	viral	JJ
cord-313312-h607itv2	62	28	particles	particle	NNS
cord-313312-h607itv2	62	29	was	be	VBD
cord-313312-h607itv2	62	30	weakened	weaken	VBN
cord-313312-h607itv2	62	31	by	by	IN
cord-313312-h607itv2	62	32	pre	pre	JJ
cord-313312-h607itv2	62	33	-	-	JJ
cord-313312-h607itv2	62	34	existing	existing	JJ
cord-313312-h607itv2	62	35	immunity	immunity	NN
cord-313312-h607itv2	62	36	,	,	,
cord-313312-h607itv2	62	37	whereas	whereas	IN
cord-313312-h607itv2	62	38	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	62	39	was	be	VBD
cord-313312-h607itv2	62	40	enhanced	enhance	VBN
cord-313312-h607itv2	62	41	at	at	IN
cord-313312-h607itv2	62	42	a	a	DT
cord-313312-h607itv2	62	43	higher	high	JJR
cord-313312-h607itv2	62	44	dose	dose	NN
cord-313312-h607itv2	62	45	of	of	IN
cord-313312-h607itv2	62	46	8.0	8.0	CD
cord-313312-h607itv2	62	47	×	×	NN
cord-313312-h607itv2	62	48	10	10	CD
cord-313312-h607itv2	62	49	10	10	CD
cord-313312-h607itv2	62	50	-1.6	-1.6	CD
cord-313312-h607itv2	62	51	×	×	NN
cord-313312-h607itv2	62	52	10	10	CD
cord-313312-h607itv2	62	53	11	11	CD
cord-313312-h607itv2	62	54	viral	viral	JJ
cord-313312-h607itv2	62	55	particles	particle	NNS
cord-313312-h607itv2	62	56	.	.	.
cord-313312-h607itv2	63	1	In	in	IN
cord-313312-h607itv2	63	2	a	a	DT
cord-313312-h607itv2	63	3	mouse	mouse	NN
cord-313312-h607itv2	63	4	model	model	NN
cord-313312-h607itv2	63	5	,	,	,
cord-313312-h607itv2	63	6	pre	pre	JJ
cord-313312-h607itv2	63	7	-	-	JJ
cord-313312-h607itv2	63	8	existing	existing	JJ
cord-313312-h607itv2	63	9	anti	anti	JJ
cord-313312-h607itv2	63	10	-	-	JJ
cord-313312-h607itv2	63	11	Ad5	ad5	JJ
cord-313312-h607itv2	63	12	neutralizing	neutralize	VBG
cord-313312-h607itv2	63	13	antibodies	antibody	NNS
cord-313312-h607itv2	63	14	were	be	VBD
cord-313312-h607itv2	63	15	observed	observe	VBN
cord-313312-h607itv2	63	16	to	to	TO
cord-313312-h607itv2	63	17	severely	severely	RB
cord-313312-h607itv2	63	18	hamper	hamper	VB
cord-313312-h607itv2	63	19	the	the	DT
cord-313312-h607itv2	63	20	induction	induction	NN
cord-313312-h607itv2	63	21	of	of	IN
cord-313312-h607itv2	63	22	both	both	CC
cord-313312-h607itv2	63	23	cellular	cellular	JJ
cord-313312-h607itv2	63	24	and	and	CC
cord-313312-h607itv2	63	25	humoral	humoral	JJ
cord-313312-h607itv2	63	26	responses	response	NNS
cord-313312-h607itv2	63	27	by	by	IN
cord-313312-h607itv2	63	28	a	a	DT
cord-313312-h607itv2	63	29	recombinant	recombinant	JJ
cord-313312-h607itv2	63	30	Ad5-Ebolavirus	ad5-ebolavirus	NN
cord-313312-h607itv2	63	31	glycoprotein	glycoprotein	NN
cord-313312-h607itv2	63	32	vaccine	vaccine	NN
cord-313312-h607itv2	63	33	[	[	-LRB-
cord-313312-h607itv2	63	34	47	47	CD
cord-313312-h607itv2	63	35	]	]	-RRB-
cord-313312-h607itv2	63	36	.	.	.
cord-313312-h607itv2	64	1	Likewise	likewise	RB
cord-313312-h607itv2	64	2	,	,	,
cord-313312-h607itv2	64	3	a	a	DT
cord-313312-h607itv2	64	4	recombinant	recombinant	JJ
cord-313312-h607itv2	64	5	Ad5	ad5	CD
cord-313312-h607itv2	64	6	vector	vector	NN
cord-313312-h607itv2	64	7	expressing	express	VBG
cord-313312-h607itv2	64	8	the	the	DT
cord-313312-h607itv2	64	9	Human	Human	NNP
cord-313312-h607itv2	64	10	Immunodeficiency	Immunodeficiency	NNP
cord-313312-h607itv2	64	11	Virus-1	Virus-1	NNP
cord-313312-h607itv2	64	12	(	(	-LRB-
cord-313312-h607itv2	64	13	HIV	HIV	NNP
cord-313312-h607itv2	64	14	)	)	-RRB-
cord-313312-h607itv2	64	15	gag	gag	NN
cord-313312-h607itv2	64	16	gene	gene	NN
cord-313312-h607itv2	64	17	showed	show	VBD
cord-313312-h607itv2	64	18	diminished	diminish	VBN
cord-313312-h607itv2	64	19	,	,	,
cord-313312-h607itv2	64	20	but	but	CC
cord-313312-h607itv2	64	21	not	not	RB
cord-313312-h607itv2	64	22	complete	complete	JJ
cord-313312-h607itv2	64	23	,	,	,
cord-313312-h607itv2	64	24	abrogation	abrogation	NN
cord-313312-h607itv2	64	25	of	of	IN
cord-313312-h607itv2	64	26	gag	gag	NN
cord-313312-h607itv2	64	27	-	-	HYPH
cord-313312-h607itv2	64	28	specific	specific	JJ
cord-313312-h607itv2	64	29	cellular	cellular	JJ
cord-313312-h607itv2	64	30	immune	immune	JJ
cord-313312-h607itv2	64	31	responses	response	NNS
cord-313312-h607itv2	64	32	following	follow	VBG
cord-313312-h607itv2	64	33	the	the	DT
cord-313312-h607itv2	64	34	vaccination	vaccination	NN
cord-313312-h607itv2	64	35	of	of	IN
cord-313312-h607itv2	64	36	rhesus	rhesu	NNS
cord-313312-h607itv2	64	37	monkeys	monkey	NNS
cord-313312-h607itv2	64	38	pre	pre	VBP
cord-313312-h607itv2	64	39	-	-	VBD
cord-313312-h607itv2	64	40	exposed	expose	VBN
cord-313312-h607itv2	64	41	to	to	IN
cord-313312-h607itv2	64	42	an	an	DT
cord-313312-h607itv2	64	43	empty	empty	JJ
cord-313312-h607itv2	64	44	Ad5	ad5	CD
cord-313312-h607itv2	64	45	vector	vector	NN
cord-313312-h607itv2	64	46	[	[	-LRB-
cord-313312-h607itv2	64	47	48	48	CD
cord-313312-h607itv2	64	48	]	]	-RRB-
cord-313312-h607itv2	64	49	.	.	.
cord-313312-h607itv2	65	1	Nonetheless	nonetheless	RB
cord-313312-h607itv2	65	2	,	,	,
cord-313312-h607itv2	65	3	there	there	EX
cord-313312-h607itv2	65	4	exists	exist	VBZ
cord-313312-h607itv2	65	5	conflicting	conflict	VBG
cord-313312-h607itv2	65	6	data	datum	NNS
cord-313312-h607itv2	65	7	that	that	WDT
cord-313312-h607itv2	65	8	pre	pre	JJ
cord-313312-h607itv2	65	9	-	-	JJ
cord-313312-h607itv2	65	10	existing	existing	JJ
cord-313312-h607itv2	65	11	anti	anti	JJ
cord-313312-h607itv2	65	12	-	-	JJ
cord-313312-h607itv2	65	13	Ad5	ad5	JJ
cord-313312-h607itv2	65	14	may	may	MD
cord-313312-h607itv2	65	15	not	not	RB
cord-313312-h607itv2	65	16	affect	affect	VB
cord-313312-h607itv2	65	17	the	the	DT
cord-313312-h607itv2	65	18	induction	induction	NN
cord-313312-h607itv2	65	19	of	of	IN
cord-313312-h607itv2	65	20	cytotoxic	cytotoxic	JJ
cord-313312-h607itv2	65	21	T	t	NN
cord-313312-h607itv2	65	22	-	-	HYPH
cord-313312-h607itv2	65	23	cell	cell	NN
cord-313312-h607itv2	65	24	responses	response	NNS
cord-313312-h607itv2	65	25	,	,	,
cord-313312-h607itv2	65	26	indicating	indicate	VBG
cord-313312-h607itv2	65	27	that	that	IN
cord-313312-h607itv2	65	28	more	more	JJR
cord-313312-h607itv2	65	29	studies	study	NNS
cord-313312-h607itv2	65	30	may	may	MD
cord-313312-h607itv2	65	31	be	be	VB
cord-313312-h607itv2	65	32	required	require	VBN
cord-313312-h607itv2	65	33	to	to	TO
cord-313312-h607itv2	65	34	resolve	resolve	VB
cord-313312-h607itv2	65	35	these	these	DT
cord-313312-h607itv2	65	36	discrepancies	discrepancy	NNS
cord-313312-h607itv2	65	37	[	[	-LRB-
cord-313312-h607itv2	65	38	49	49	CD
cord-313312-h607itv2	65	39	]	]	-RRB-
cord-313312-h607itv2	65	40	.	.	.
cord-313312-h607itv2	66	1	The	the	DT
cord-313312-h607itv2	66	2	high	high	JJ
cord-313312-h607itv2	66	3	seroprevalence	seroprevalence	NN
cord-313312-h607itv2	66	4	of	of	IN
cord-313312-h607itv2	66	5	anti	anti	JJ
cord-313312-h607itv2	66	6	-	-	JJ
cord-313312-h607itv2	66	7	Ad5	ad5	JJ
cord-313312-h607itv2	66	8	immunity	immunity	NN
cord-313312-h607itv2	66	9	has	have	VBZ
cord-313312-h607itv2	66	10	pivoted	pivot	VBN
cord-313312-h607itv2	66	11	the	the	DT
cord-313312-h607itv2	66	12	development	development	NN
cord-313312-h607itv2	66	13	of	of	IN
cord-313312-h607itv2	66	14	genetically	genetically	RB
cord-313312-h607itv2	66	15	-	-	HYPH
cord-313312-h607itv2	66	16	modified	modify	VBN
cord-313312-h607itv2	66	17	AdV	adv	NN
cord-313312-h607itv2	66	18	and	and	CC
cord-313312-h607itv2	66	19	the	the	DT
cord-313312-h607itv2	66	20	search	search	NN
cord-313312-h607itv2	66	21	of	of	IN
cord-313312-h607itv2	66	22	rarer	rare	JJR
cord-313312-h607itv2	66	23	AdV	adv	NN
cord-313312-h607itv2	66	24	serotypes	serotype	NNS
cord-313312-h607itv2	66	25	for	for	IN
cord-313312-h607itv2	66	26	use	use	NN
cord-313312-h607itv2	66	27	as	as	IN
cord-313312-h607itv2	66	28	vectors	vector	NNS
cord-313312-h607itv2	66	29	,	,	,
cord-313312-h607itv2	66	30	in	in	IN
cord-313312-h607itv2	66	31	hopes	hope	NNS
cord-313312-h607itv2	66	32	that	that	IN
cord-313312-h607itv2	66	33	these	these	DT
cord-313312-h607itv2	66	34	viruses	virus	NNS
cord-313312-h607itv2	66	35	may	may	MD
cord-313312-h607itv2	66	36	circumvent	circumvent	VB
cord-313312-h607itv2	66	37	the	the	DT
cord-313312-h607itv2	66	38	effects	effect	NNS
cord-313312-h607itv2	66	39	of	of	IN
cord-313312-h607itv2	66	40	pre	pre	JJ
cord-313312-h607itv2	66	41	-	-	JJ
cord-313312-h607itv2	66	42	existing	existing	JJ
cord-313312-h607itv2	66	43	anti	anti	JJ
cord-313312-h607itv2	66	44	-	-	JJ
cord-313312-h607itv2	66	45	Ad5	ad5	JJ
cord-313312-h607itv2	66	46	immunity	immunity	NN
cord-313312-h607itv2	66	47	[	[	-LRB-
cord-313312-h607itv2	66	48	50	50	CD
cord-313312-h607itv2	66	49	,	,	,
cord-313312-h607itv2	66	50	51	51	CD
cord-313312-h607itv2	66	51	]	]	-RRB-
cord-313312-h607itv2	66	52	.	.	.
cord-313312-h607itv2	67	1	However	however	RB
cord-313312-h607itv2	67	2	,	,	,
cord-313312-h607itv2	67	3	there	there	EX
cord-313312-h607itv2	67	4	remains	remain	VBZ
cord-313312-h607itv2	67	5	the	the	DT
cord-313312-h607itv2	67	6	possibility	possibility	NN
cord-313312-h607itv2	67	7	of	of	IN
cord-313312-h607itv2	67	8	cross	cross	NN
cord-313312-h607itv2	67	9	-	-	NN
cord-313312-h607itv2	67	10	reactivity	reactivity	NN
cord-313312-h607itv2	67	11	between	between	IN
cord-313312-h607itv2	67	12	antibodies	antibody	NNS
cord-313312-h607itv2	67	13	against	against	IN
cord-313312-h607itv2	67	14	the	the	DT
cord-313312-h607itv2	67	15	different	different	JJ
cord-313312-h607itv2	67	16	AdV	adv	NN
cord-313312-h607itv2	67	17	serotypes	serotype	NNS
cord-313312-h607itv2	67	18	,	,	,
cord-313312-h607itv2	67	19	which	which	WDT
cord-313312-h607itv2	67	20	could	could	MD
cord-313312-h607itv2	67	21	in	in	IN
cord-313312-h607itv2	67	22	turn	turn	NN
cord-313312-h607itv2	67	23	potentially	potentially	RB
cord-313312-h607itv2	67	24	influence	influence	VB
cord-313312-h607itv2	67	25	the	the	DT
cord-313312-h607itv2	67	26	efficacy	efficacy	NN
cord-313312-h607itv2	67	27	of	of	IN
cord-313312-h607itv2	67	28	these	these	DT
cord-313312-h607itv2	67	29	rarer	rare	JJR
cord-313312-h607itv2	67	30	AdV	adv	NN
cord-313312-h607itv2	67	31	as	as	IN
cord-313312-h607itv2	67	32	vaccine	vaccine	NN
cord-313312-h607itv2	67	33	vectors	vector	NNS
cord-313312-h607itv2	67	34	.	.	.
cord-313312-h607itv2	68	1	Indeed	indeed	RB
cord-313312-h607itv2	68	2	,	,	,
cord-313312-h607itv2	68	3	investigations	investigation	NNS
cord-313312-h607itv2	68	4	by	by	IN
cord-313312-h607itv2	68	5	Heemskerk	Heemskerk	NNP
cord-313312-h607itv2	68	6	et	et	NNP
cord-313312-h607itv2	68	7	al	al	NNP
cord-313312-h607itv2	68	8	.	.	NNP
cord-313312-h607itv2	68	9	have	have	VBP
cord-313312-h607itv2	68	10	shown	show	VBN
cord-313312-h607itv2	68	11	that	that	IN
cord-313312-h607itv2	68	12	Ad5-specific	Ad5-specific	NNP
cord-313312-h607itv2	68	13	CD4	CD4	NNP
cord-313312-h607itv2	68	14	+	+	CC
cord-313312-h607itv2	68	15	T	T	NNP
cord-313312-h607itv2	68	16	-	-	HYPH
cord-313312-h607itv2	68	17	cells	cell	NNS
cord-313312-h607itv2	68	18	could	could	MD
cord-313312-h607itv2	68	19	cross	cross	VB
cord-313312-h607itv2	68	20	-	-	VB
cord-313312-h607itv2	68	21	react	react	VB
cord-313312-h607itv2	68	22	with	with	IN
cord-313312-h607itv2	68	23	other	other	JJ
cord-313312-h607itv2	68	24	AdV	adv	NN
cord-313312-h607itv2	68	25	serotypes	serotype	NNS
cord-313312-h607itv2	68	26	including	include	VBG
cord-313312-h607itv2	68	27	but	but	CC
cord-313312-h607itv2	68	28	not	not	RB
cord-313312-h607itv2	68	29	limited	limited	JJ
cord-313312-h607itv2	68	30	to	to	IN
cord-313312-h607itv2	68	31	Ad1	ad1	NN
cord-313312-h607itv2	68	32	,	,	,
cord-313312-h607itv2	68	33	Ad3	ad3	CD
cord-313312-h607itv2	68	34	,	,	,
cord-313312-h607itv2	68	35	Ad7	ad7	NN
cord-313312-h607itv2	68	36	,	,	,
cord-313312-h607itv2	68	37	and	and	CC
cord-313312-h607itv2	68	38	Ad35	Ad35	NNP
cord-313312-h607itv2	68	39	,	,	,
cord-313312-h607itv2	68	40	suggesting	suggest	VBG
cord-313312-h607itv2	68	41	that	that	IN
cord-313312-h607itv2	68	42	the	the	DT
cord-313312-h607itv2	68	43	different	different	JJ
cord-313312-h607itv2	68	44	AdV	adv	NN
cord-313312-h607itv2	68	45	serotypes	serotype	NNS
cord-313312-h607itv2	68	46	share	share	VBP
cord-313312-h607itv2	68	47	similar	similar	JJ
cord-313312-h607itv2	68	48	T	t	NN
cord-313312-h607itv2	68	49	-	-	HYPH
cord-313312-h607itv2	68	50	cell	cell	NN
cord-313312-h607itv2	68	51	epitopes	epitope	NNS
cord-313312-h607itv2	68	52	[	[	-LRB-
cord-313312-h607itv2	68	53	52	52	CD
cord-313312-h607itv2	68	54	]	]	-RRB-
cord-313312-h607itv2	68	55	.	.	.
cord-313312-h607itv2	69	1	Several	several	JJ
cord-313312-h607itv2	69	2	studies	study	NNS
cord-313312-h607itv2	69	3	have	have	VBP
cord-313312-h607itv2	69	4	attempted	attempt	VBN
cord-313312-h607itv2	69	5	to	to	TO
cord-313312-h607itv2	69	6	further	further	RB
cord-313312-h607itv2	69	7	explore	explore	VB
cord-313312-h607itv2	69	8	this	this	DT
cord-313312-h607itv2	69	9	school	school	NN
cord-313312-h607itv2	69	10	of	of	IN
cord-313312-h607itv2	69	11	thought	thought	NN
cord-313312-h607itv2	69	12	,	,	,
cord-313312-h607itv2	69	13	and	and	CC
cord-313312-h607itv2	69	14	their	-PRON-	PRP$
cord-313312-h607itv2	69	15	results	result	NNS
cord-313312-h607itv2	69	16	have	have	VBP
cord-313312-h607itv2	69	17	provided	provide	VBN
cord-313312-h607itv2	69	18	greater	great	JJR
cord-313312-h607itv2	69	19	insight	insight	NN
cord-313312-h607itv2	69	20	into	into	IN
cord-313312-h607itv2	69	21	this	this	DT
cord-313312-h607itv2	69	22	particular	particular	JJ
cord-313312-h607itv2	69	23	topic	topic	NN
cord-313312-h607itv2	69	24	.	.	.
cord-313312-h607itv2	70	1	Ad35	Ad35	NNP
cord-313312-h607itv2	70	2	is	be	VBZ
cord-313312-h607itv2	70	3	one	one	CD
cord-313312-h607itv2	70	4	of	of	IN
cord-313312-h607itv2	70	5	the	the	DT
cord-313312-h607itv2	70	6	rarest	rare	JJS
cord-313312-h607itv2	70	7	human	human	JJ
cord-313312-h607itv2	70	8	AdV	adv	NN
cord-313312-h607itv2	70	9	serotypes	serotype	NNS
cord-313312-h607itv2	70	10	,	,	,
cord-313312-h607itv2	70	11	with	with	IN
cord-313312-h607itv2	70	12	a	a	DT
cord-313312-h607itv2	70	13	seroprevalence	seroprevalence	NN
cord-313312-h607itv2	70	14	of	of	IN
cord-313312-h607itv2	70	15	less	less	JJR
cord-313312-h607itv2	70	16	than	than	IN
cord-313312-h607itv2	70	17	7	7	CD
cord-313312-h607itv2	70	18	%	%	NN
cord-313312-h607itv2	70	19	in	in	IN
cord-313312-h607itv2	70	20	the	the	DT
cord-313312-h607itv2	70	21	population	population	NN
cord-313312-h607itv2	70	22	.	.	.
cord-313312-h607itv2	71	1	In	in	IN
cord-313312-h607itv2	71	2	an	an	DT
cord-313312-h607itv2	71	3	attempt	attempt	NN
cord-313312-h607itv2	71	4	to	to	TO
cord-313312-h607itv2	71	5	determine	determine	VB
cord-313312-h607itv2	71	6	its	-PRON-	PRP$
cord-313312-h607itv2	71	7	potential	potential	NN
cord-313312-h607itv2	71	8	as	as	IN
cord-313312-h607itv2	71	9	an	an	DT
cord-313312-h607itv2	71	10	alternative	alternative	JJ
cord-313312-h607itv2	71	11	vector	vector	NN
cord-313312-h607itv2	71	12	to	to	IN
cord-313312-h607itv2	71	13	Ad5	ad5	CD
cord-313312-h607itv2	71	14	,	,	,
cord-313312-h607itv2	71	15	Barouch	Barouch	NNP
cord-313312-h607itv2	71	16	et	et	NNP
cord-313312-h607itv2	71	17	al	al	NNP
cord-313312-h607itv2	71	18	.	.	.
cord-313312-h607itv2	72	1	compared	compare	VBN
cord-313312-h607itv2	72	2	the	the	DT
cord-313312-h607itv2	72	3	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	72	4	of	of	IN
cord-313312-h607itv2	72	5	a	a	DT
cord-313312-h607itv2	72	6	rAd35	rad35	NN
cord-313312-h607itv2	72	7	vaccine	vaccine	NN
cord-313312-h607itv2	72	8	expressing	express	VBG
cord-313312-h607itv2	72	9	Simian	Simian	NNP
cord-313312-h607itv2	72	10	Immunodeficiency	Immunodeficiency	NNP
cord-313312-h607itv2	72	11	Virus	virus	NN
cord-313312-h607itv2	72	12	(	(	-LRB-
cord-313312-h607itv2	72	13	SIV)-Gag	SIV)-Gag	NNP
cord-313312-h607itv2	72	14	versus	versus	IN
cord-313312-h607itv2	72	15	a	a	DT
cord-313312-h607itv2	72	16	rAd5	rad5	PRP$
cord-313312-h607itv2	72	17	SIV	SIV	NNP
cord-313312-h607itv2	72	18	-	-	HYPH
cord-313312-h607itv2	72	19	Gag	Gag	NNP
cord-313312-h607itv2	72	20	vaccine	vaccine	NN
cord-313312-h607itv2	72	21	in	in	IN
cord-313312-h607itv2	72	22	Ad5	ad5	CD
cord-313312-h607itv2	72	23	immune	immune	JJ
cord-313312-h607itv2	72	24	C57	C57	NNP
cord-313312-h607itv2	72	25	/	/	SYM
cord-313312-h607itv2	72	26	BL6	BL6	NNP
cord-313312-h607itv2	72	27	mice	mouse	NNS
cord-313312-h607itv2	72	28	[	[	-LRB-
cord-313312-h607itv2	72	29	53	53	CD
cord-313312-h607itv2	72	30	]	]	-RRB-
cord-313312-h607itv2	72	31	.	.	.
cord-313312-h607itv2	73	1	Indeed	indeed	RB
cord-313312-h607itv2	73	2	,	,	,
cord-313312-h607itv2	73	3	the	the	DT
cord-313312-h607itv2	73	4	efficacy	efficacy	NN
cord-313312-h607itv2	73	5	of	of	IN
cord-313312-h607itv2	73	6	the	the	DT
cord-313312-h607itv2	73	7	rAd35-Gag	rAd35-Gag	NNP
cord-313312-h607itv2	73	8	vaccine	vaccine	NN
cord-313312-h607itv2	73	9	was	be	VBD
cord-313312-h607itv2	73	10	unaffected	unaffected	JJ
cord-313312-h607itv2	73	11	even	even	RB
cord-313312-h607itv2	73	12	by	by	IN
cord-313312-h607itv2	73	13	high	high	JJ
cord-313312-h607itv2	73	14	levels	level	NNS
cord-313312-h607itv2	73	15	of	of	IN
cord-313312-h607itv2	73	16	pre	pre	JJ
cord-313312-h607itv2	73	17	-	-	JJ
cord-313312-h607itv2	73	18	existing	existing	JJ
cord-313312-h607itv2	73	19	Ad5	ad5	CD
cord-313312-h607itv2	73	20	immunity	immunity	NN
cord-313312-h607itv2	73	21	,	,	,
cord-313312-h607itv2	73	22	indicating	indicate	VBG
cord-313312-h607itv2	73	23	the	the	DT
cord-313312-h607itv2	73	24	absence	absence	NN
cord-313312-h607itv2	73	25	of	of	IN
cord-313312-h607itv2	73	26	a	a	DT
cord-313312-h607itv2	73	27	cross	cross	JJ
cord-313312-h607itv2	73	28	-	-	JJ
cord-313312-h607itv2	73	29	reactive	reactive	JJ
cord-313312-h607itv2	73	30	response	response	NN
cord-313312-h607itv2	73	31	between	between	IN
cord-313312-h607itv2	73	32	Ad5	ad5	CD
cord-313312-h607itv2	73	33	and	and	CC
cord-313312-h607itv2	73	34	Ad35	Ad35	NNP
cord-313312-h607itv2	73	35	.	.	.
cord-313312-h607itv2	74	1	Likewise	likewise	RB
cord-313312-h607itv2	74	2	,	,	,
cord-313312-h607itv2	74	3	the	the	DT
cord-313312-h607itv2	74	4	presence	presence	NN
cord-313312-h607itv2	74	5	of	of	IN
cord-313312-h607itv2	74	6	anti	anti	JJ
cord-313312-h607itv2	74	7	-	-	JJ
cord-313312-h607itv2	74	8	Ad5	ad5	JJ
cord-313312-h607itv2	74	9	immunity	immunity	NN
cord-313312-h607itv2	74	10	did	do	VBD
cord-313312-h607itv2	74	11	not	not	RB
cord-313312-h607itv2	74	12	affect	affect	VB
cord-313312-h607itv2	74	13	the	the	DT
cord-313312-h607itv2	74	14	efficacy	efficacy	NN
cord-313312-h607itv2	74	15	of	of	IN
cord-313312-h607itv2	74	16	a	a	DT
cord-313312-h607itv2	74	17	rAd11-Gag	rad11-gag	CD
cord-313312-h607itv2	74	18	vector	vector	NN
cord-313312-h607itv2	74	19	vaccine	vaccine	NN
cord-313312-h607itv2	74	20	in	in	IN
cord-313312-h607itv2	74	21	mice	mouse	NNS
cord-313312-h607itv2	74	22	.	.	.
cord-313312-h607itv2	75	1	Interestingly	interestingly	RB
cord-313312-h607itv2	75	2	,	,	,
cord-313312-h607itv2	75	3	pre	pre	JJ
cord-313312-h607itv2	75	4	-	-	JJ
cord-313312-h607itv2	75	5	existing	existing	JJ
cord-313312-h607itv2	75	6	anti	anti	JJ
cord-313312-h607itv2	75	7	-	-	JJ
cord-313312-h607itv2	75	8	Ad11	ad11	JJ
cord-313312-h607itv2	75	9	immunity	immunity	NN
cord-313312-h607itv2	75	10	could	could	MD
cord-313312-h607itv2	75	11	suppress	suppress	VB
cord-313312-h607itv2	75	12	cellular	cellular	JJ
cord-313312-h607itv2	75	13	immune	immune	JJ
cord-313312-h607itv2	75	14	responses	response	NNS
cord-313312-h607itv2	75	15	elicited	elicit	VBN
cord-313312-h607itv2	75	16	by	by	IN
cord-313312-h607itv2	75	17	the	the	DT
cord-313312-h607itv2	75	18	rAd35-Gag	rAd35-Gag	NNP
cord-313312-h607itv2	75	19	vaccine	vaccine	NN
cord-313312-h607itv2	75	20	,	,	,
cord-313312-h607itv2	75	21	suggesting	suggest	VBG
cord-313312-h607itv2	75	22	some	some	DT
cord-313312-h607itv2	75	23	cross	cross	NN
cord-313312-h607itv2	75	24	-	-	NN
cord-313312-h607itv2	75	25	reactivity	reactivity	NN
cord-313312-h607itv2	75	26	between	between	IN
cord-313312-h607itv2	75	27	Ad11	Ad11	NNP
cord-313312-h607itv2	75	28	and	and	CC
cord-313312-h607itv2	75	29	Ad35	Ad35	NNP
cord-313312-h607itv2	75	30	immune	immune	JJ
cord-313312-h607itv2	75	31	responses	response	NNS
cord-313312-h607itv2	75	32	[	[	-LRB-
cord-313312-h607itv2	75	33	54	54	CD
cord-313312-h607itv2	75	34	]	]	-RRB-
cord-313312-h607itv2	75	35	.	.	.
cord-313312-h607itv2	76	1	The	the	DT
cord-313312-h607itv2	76	2	inhibitory	inhibitory	JJ
cord-313312-h607itv2	76	3	effect	effect	NN
cord-313312-h607itv2	76	4	of	of	IN
cord-313312-h607itv2	76	5	pre	pre	JJ
cord-313312-h607itv2	76	6	-	-	JJ
cord-313312-h607itv2	76	7	existing	existing	JJ
cord-313312-h607itv2	76	8	antibodies	antibody	NNS
cord-313312-h607itv2	76	9	to	to	TO
cord-313312-h607itv2	76	10	AdV	adv	NN
cord-313312-h607itv2	76	11	remains	remain	VBZ
cord-313312-h607itv2	76	12	a	a	DT
cord-313312-h607itv2	76	13	challenge	challenge	NN
cord-313312-h607itv2	76	14	for	for	IN
cord-313312-h607itv2	76	15	their	-PRON-	PRP$
cord-313312-h607itv2	76	16	use	use	NN
cord-313312-h607itv2	76	17	as	as	IN
cord-313312-h607itv2	76	18	viral	viral	JJ
cord-313312-h607itv2	76	19	vectors	vector	NNS
cord-313312-h607itv2	76	20	,	,	,
cord-313312-h607itv2	76	21	and	and	CC
cord-313312-h607itv2	76	22	the	the	DT
cord-313312-h607itv2	76	23	development	development	NN
cord-313312-h607itv2	76	24	of	of	IN
cord-313312-h607itv2	76	25	alternative	alternative	JJ
cord-313312-h607itv2	76	26	serotypes	serotype	NNS
cord-313312-h607itv2	76	27	remains	remain	VBZ
cord-313312-h607itv2	76	28	to	to	TO
cord-313312-h607itv2	76	29	be	be	VB
cord-313312-h607itv2	76	30	one	one	CD
cord-313312-h607itv2	76	31	of	of	IN
cord-313312-h607itv2	76	32	the	the	DT
cord-313312-h607itv2	76	33	best	good	JJS
cord-313312-h607itv2	76	34	strategies	strategy	NNS
cord-313312-h607itv2	76	35	to	to	TO
cord-313312-h607itv2	76	36	circumvent	circumvent	VB
cord-313312-h607itv2	76	37	this	this	DT
cord-313312-h607itv2	76	38	limitation	limitation	NN
cord-313312-h607itv2	76	39	.	.	.
cord-313312-h607itv2	77	1	The	the	DT
cord-313312-h607itv2	77	2	history	history	NN
cord-313312-h607itv2	77	3	of	of	IN
cord-313312-h607itv2	77	4	mankind	mankind	NN
cord-313312-h607itv2	77	5	is	be	VBZ
cord-313312-h607itv2	77	6	intricately	intricately	RB
cord-313312-h607itv2	77	7	intertwined	intertwine	VBN
cord-313312-h607itv2	77	8	with	with	IN
cord-313312-h607itv2	77	9	that	that	DT
cord-313312-h607itv2	77	10	of	of	IN
cord-313312-h607itv2	77	11	influenza	influenza	NN
cord-313312-h607itv2	77	12	,	,	,
cord-313312-h607itv2	77	13	and	and	CC
cord-313312-h607itv2	77	14	the	the	DT
cord-313312-h607itv2	77	15	virus	virus	NN
cord-313312-h607itv2	77	16	remains	remain	VBZ
cord-313312-h607itv2	77	17	one	one	CD
cord-313312-h607itv2	77	18	of	of	IN
cord-313312-h607itv2	77	19	the	the	DT
cord-313312-h607itv2	77	20	top	top	JJ
cord-313312-h607itv2	77	21	10	10	CD
cord-313312-h607itv2	77	22	threats	threat	NNS
cord-313312-h607itv2	77	23	to	to	IN
cord-313312-h607itv2	77	24	global	global	JJ
cord-313312-h607itv2	77	25	health	health	NN
cord-313312-h607itv2	77	26	.	.	.
cord-313312-h607itv2	78	1	Estimates	estimate	NNS
cord-313312-h607itv2	78	2	indicate	indicate	VBP
cord-313312-h607itv2	78	3	that	that	IN
cord-313312-h607itv2	78	4	there	there	EX
cord-313312-h607itv2	78	5	are	be	VBP
cord-313312-h607itv2	78	6	approximately	approximately	RB
cord-313312-h607itv2	78	7	1	1	CD
cord-313312-h607itv2	78	8	billion	billion	CD
cord-313312-h607itv2	78	9	cases	case	NNS
cord-313312-h607itv2	78	10	globally	globally	RB
cord-313312-h607itv2	78	11	each	each	DT
cord-313312-h607itv2	78	12	year	year	NN
cord-313312-h607itv2	78	13	,	,	,
cord-313312-h607itv2	78	14	of	of	IN
cord-313312-h607itv2	78	15	which	which	WDT
cord-313312-h607itv2	78	16	3	3	CD
cord-313312-h607itv2	78	17	to	to	IN
cord-313312-h607itv2	78	18	5	5	CD
cord-313312-h607itv2	78	19	million	million	CD
cord-313312-h607itv2	78	20	are	be	VBP
cord-313312-h607itv2	78	21	severe	severe	JJ
cord-313312-h607itv2	78	22	cases	case	NNS
cord-313312-h607itv2	78	23	and	and	CC
cord-313312-h607itv2	78	24	up	up	IN
cord-313312-h607itv2	78	25	to	to	TO
cord-313312-h607itv2	78	26	650,000	650,000	CD
cord-313312-h607itv2	78	27	eventually	eventually	RB
cord-313312-h607itv2	78	28	succumb	succumb	VB
cord-313312-h607itv2	78	29	to	to	IN
cord-313312-h607itv2	78	30	the	the	DT
cord-313312-h607itv2	78	31	disease	disease	NN
cord-313312-h607itv2	78	32	[	[	-LRB-
cord-313312-h607itv2	78	33	55	55	CD
cord-313312-h607itv2	78	34	]	]	-RRB-
cord-313312-h607itv2	78	35	.	.	.
cord-313312-h607itv2	79	1	Combined	combine	VBN
cord-313312-h607itv2	79	2	with	with	IN
cord-313312-h607itv2	79	3	the	the	DT
cord-313312-h607itv2	79	4	economic	economic	JJ
cord-313312-h607itv2	79	5	impact	impact	NN
cord-313312-h607itv2	79	6	from	from	IN
cord-313312-h607itv2	79	7	the	the	DT
cord-313312-h607itv2	79	8	loss	loss	NN
cord-313312-h607itv2	79	9	of	of	IN
cord-313312-h607itv2	79	10	work	work	NN
cord-313312-h607itv2	79	11	productivity	productivity	NN
cord-313312-h607itv2	79	12	,	,	,
cord-313312-h607itv2	79	13	a	a	DT
cord-313312-h607itv2	79	14	proper	proper	JJ
cord-313312-h607itv2	79	15	and	and	CC
cord-313312-h607itv2	79	16	robust	robust	JJ
cord-313312-h607itv2	79	17	framework	framework	NN
cord-313312-h607itv2	79	18	is	be	VBZ
cord-313312-h607itv2	79	19	required	require	VBN
cord-313312-h607itv2	79	20	to	to	TO
cord-313312-h607itv2	79	21	counter	counter	VB
cord-313312-h607itv2	79	22	this	this	DT
cord-313312-h607itv2	79	23	threat	threat	NN
cord-313312-h607itv2	79	24	.	.	.
cord-313312-h607itv2	80	1	The	the	DT
cord-313312-h607itv2	80	2	2019	2019	CD
cord-313312-h607itv2	80	3	Global	Global	NNP
cord-313312-h607itv2	80	4	Influenza	Influenza	NNP
cord-313312-h607itv2	80	5	Strategies	Strategies	NNPS
cord-313312-h607itv2	80	6	recommend	recommend	VBP
cord-313312-h607itv2	80	7	vaccination	vaccination	NN
cord-313312-h607itv2	80	8	as	as	IN
cord-313312-h607itv2	80	9	the	the	DT
cord-313312-h607itv2	80	10	most	most	RBS
cord-313312-h607itv2	80	11	effective	effective	JJ
cord-313312-h607itv2	80	12	intervention	intervention	NN
cord-313312-h607itv2	80	13	to	to	TO
cord-313312-h607itv2	80	14	mitigate	mitigate	VB
cord-313312-h607itv2	80	15	the	the	DT
cord-313312-h607itv2	80	16	impact	impact	NN
cord-313312-h607itv2	80	17	of	of	IN
cord-313312-h607itv2	80	18	influenza	influenza	NN
cord-313312-h607itv2	80	19	[	[	-LRB-
cord-313312-h607itv2	80	20	56	56	CD
cord-313312-h607itv2	80	21	]	]	-RRB-
cord-313312-h607itv2	80	22	.	.	.
cord-313312-h607itv2	81	1	Three	three	CD
cord-313312-h607itv2	81	2	types	type	NNS
cord-313312-h607itv2	81	3	of	of	IN
cord-313312-h607itv2	81	4	influenza	influenza	NN
cord-313312-h607itv2	81	5	vaccines	vaccine	NNS
cord-313312-h607itv2	81	6	are	be	VBP
cord-313312-h607itv2	81	7	licensed	license	VBN
cord-313312-h607itv2	81	8	for	for	IN
cord-313312-h607itv2	81	9	use	use	NN
cord-313312-h607itv2	81	10	:	:	:
cord-313312-h607itv2	81	11	(	(	-LRB-
cord-313312-h607itv2	81	12	1	1	LS
cord-313312-h607itv2	81	13	)	)	-RRB-
cord-313312-h607itv2	81	14	recombinant	recombinant	NN
cord-313312-h607itv2	81	15	,	,	,
cord-313312-h607itv2	81	16	(	(	-LRB-
cord-313312-h607itv2	81	17	2	2	LS
cord-313312-h607itv2	81	18	)	)	-RRB-
cord-313312-h607itv2	81	19	inactivated	inactivate	VBN
cord-313312-h607itv2	81	20	,	,	,
cord-313312-h607itv2	81	21	and	and	CC
cord-313312-h607itv2	81	22	(	(	-LRB-
cord-313312-h607itv2	81	23	3	3	LS
cord-313312-h607itv2	81	24	)	)	-RRB-
cord-313312-h607itv2	81	25	live	live	RB
cord-313312-h607itv2	81	26	-	-	HYPH
cord-313312-h607itv2	81	27	attenuated	attenuated	JJ
cord-313312-h607itv2	81	28	.	.	.
cord-313312-h607itv2	82	1	The	the	DT
cord-313312-h607itv2	82	2	three	three	CD
cord-313312-h607itv2	82	3	vaccines	vaccine	NNS
cord-313312-h607itv2	82	4	are	be	VBP
cord-313312-h607itv2	82	5	multivalent	multivalent	JJ
cord-313312-h607itv2	82	6	and	and	CC
cord-313312-h607itv2	82	7	provide	provide	VB
cord-313312-h607itv2	82	8	protection	protection	NN
cord-313312-h607itv2	82	9	against	against	IN
cord-313312-h607itv2	82	10	selected	select	VBN
cord-313312-h607itv2	82	11	influenza	influenza	NN
cord-313312-h607itv2	82	12	type	type	NN
cord-313312-h607itv2	82	13	A	a	NN
cord-313312-h607itv2	82	14	and	and	CC
cord-313312-h607itv2	82	15	type	type	NN
cord-313312-h607itv2	82	16	B	b	NN
cord-313312-h607itv2	82	17	strains	strain	NNS
cord-313312-h607itv2	82	18	that	that	WDT
cord-313312-h607itv2	82	19	are	be	VBP
cord-313312-h607itv2	82	20	predicted	predict	VBN
cord-313312-h607itv2	82	21	to	to	TO
cord-313312-h607itv2	82	22	spread	spread	VB
cord-313312-h607itv2	82	23	in	in	IN
cord-313312-h607itv2	82	24	the	the	DT
cord-313312-h607itv2	82	25	upcoming	upcoming	JJ
cord-313312-h607itv2	82	26	season	season	NN
cord-313312-h607itv2	82	27	[	[	-LRB-
cord-313312-h607itv2	82	28	57	57	CD
cord-313312-h607itv2	82	29	]	]	-RRB-
cord-313312-h607itv2	82	30	.	.	.
cord-313312-h607itv2	83	1	The	the	DT
cord-313312-h607itv2	83	2	former	former	JJ
cord-313312-h607itv2	83	3	two	two	CD
cord-313312-h607itv2	83	4	are	be	VBP
cord-313312-h607itv2	83	5	capable	capable	JJ
cord-313312-h607itv2	83	6	of	of	IN
cord-313312-h607itv2	83	7	inducing	induce	VBG
cord-313312-h607itv2	83	8	only	only	RB
cord-313312-h607itv2	83	9	IgG	igg	NN
cord-313312-h607itv2	83	10	responses	response	NNS
cord-313312-h607itv2	83	11	[	[	-LRB-
cord-313312-h607itv2	83	12	57	57	CD
cord-313312-h607itv2	83	13	,	,	,
cord-313312-h607itv2	83	14	58	58	CD
cord-313312-h607itv2	83	15	]	]	-RRB-
cord-313312-h607itv2	83	16	.	.	.
cord-313312-h607itv2	84	1	By	by	IN
cord-313312-h607itv2	84	2	contrast	contrast	NN
cord-313312-h607itv2	84	3	,	,	,
cord-313312-h607itv2	84	4	the	the	DT
cord-313312-h607itv2	84	5	live	live	RB
cord-313312-h607itv2	84	6	-	-	HYPH
cord-313312-h607itv2	84	7	attenuated	attenuate	VBN
cord-313312-h607itv2	84	8	influenza	influenza	NN
cord-313312-h607itv2	84	9	vaccine	vaccine	NN
cord-313312-h607itv2	84	10	(	(	-LRB-
cord-313312-h607itv2	84	11	LAIV	LAIV	NNP
cord-313312-h607itv2	84	12	)	)	-RRB-
cord-313312-h607itv2	84	13	can	can	MD
cord-313312-h607itv2	84	14	generate	generate	VB
cord-313312-h607itv2	84	15	strain	strain	NN
cord-313312-h607itv2	84	16	-	-	HYPH
cord-313312-h607itv2	84	17	specific	specific	JJ
cord-313312-h607itv2	84	18	IgG	igg	NN
cord-313312-h607itv2	84	19	antibodies	antibody	NNS
cord-313312-h607itv2	84	20	as	as	RB
cord-313312-h607itv2	84	21	well	well	RB
cord-313312-h607itv2	84	22	as	as	IN
cord-313312-h607itv2	84	23	mucosal	mucosal	JJ
cord-313312-h607itv2	84	24	IgA	IgA	NNP
cord-313312-h607itv2	84	25	immunity	immunity	NN
cord-313312-h607itv2	84	26	and	and	CC
cord-313312-h607itv2	84	27	T	t	NN
cord-313312-h607itv2	84	28	-	-	HYPH
cord-313312-h607itv2	84	29	cell	cell	NN
cord-313312-h607itv2	84	30	responses	response	NNS
cord-313312-h607itv2	84	31	that	that	WDT
cord-313312-h607itv2	84	32	are	be	VBP
cord-313312-h607itv2	84	33	associated	associate	VBN
cord-313312-h607itv2	84	34	with	with	IN
cord-313312-h607itv2	84	35	protection	protection	NN
cord-313312-h607itv2	84	36	from	from	IN
cord-313312-h607itv2	84	37	influenza	influenza	NN
cord-313312-h607itv2	84	38	illness	illness	NN
cord-313312-h607itv2	84	39	[	[	-LRB-
cord-313312-h607itv2	84	40	59	59	CD
cord-313312-h607itv2	84	41	,	,	,
cord-313312-h607itv2	84	42	60	60	CD
cord-313312-h607itv2	84	43	]	]	-RRB-
cord-313312-h607itv2	84	44	.	.	.
cord-313312-h607itv2	85	1	Indeed	indeed	RB
cord-313312-h607itv2	85	2	,	,	,
cord-313312-h607itv2	85	3	a	a	DT
cord-313312-h607itv2	85	4	meta	meta	NN
cord-313312-h607itv2	85	5	-	-	HYPH
cord-313312-h607itv2	85	6	analysis	analysis	NN
cord-313312-h607itv2	85	7	by	by	IN
cord-313312-h607itv2	85	8	Ambrose	Ambrose	NNP
cord-313312-h607itv2	85	9	et	et	NNP
cord-313312-h607itv2	85	10	al	al	NNP
cord-313312-h607itv2	85	11	.	.	.
cord-313312-h607itv2	86	1	on	on	IN
cord-313312-h607itv2	86	2	the	the	DT
cord-313312-h607itv2	86	3	efficacy	efficacy	NN
cord-313312-h607itv2	86	4	of	of	IN
cord-313312-h607itv2	86	5	LAIV	LAIV	NNP
cord-313312-h607itv2	86	6	in	in	IN
cord-313312-h607itv2	86	7	children	child	NNS
cord-313312-h607itv2	86	8	showed	show	VBD
cord-313312-h607itv2	86	9	that	that	IN
cord-313312-h607itv2	86	10	recipients	recipient	NNS
cord-313312-h607itv2	86	11	of	of	IN
cord-313312-h607itv2	86	12	the	the	DT
cord-313312-h607itv2	86	13	live	live	JJ
cord-313312-h607itv2	86	14	vaccine	vaccine	NN
cord-313312-h607itv2	86	15	demonstrated	demonstrate	VBD
cord-313312-h607itv2	86	16	a	a	DT
cord-313312-h607itv2	86	17	44	44	CD
cord-313312-h607itv2	86	18	%	%	NN
cord-313312-h607itv2	86	19	reduction	reduction	NN
cord-313312-h607itv2	86	20	in	in	IN
cord-313312-h607itv2	86	21	influenza	influenza	NN
cord-313312-h607itv2	86	22	cases	case	NNS
cord-313312-h607itv2	86	23	compared	compare	VBN
cord-313312-h607itv2	86	24	to	to	IN
cord-313312-h607itv2	86	25	those	those	DT
cord-313312-h607itv2	86	26	who	who	WP
cord-313312-h607itv2	86	27	received	receive	VBD
cord-313312-h607itv2	86	28	the	the	DT
cord-313312-h607itv2	86	29	trivalent	trivalent	JJ
cord-313312-h607itv2	86	30	inactivated	inactivate	VBN
cord-313312-h607itv2	86	31	vaccine	vaccine	NN
cord-313312-h607itv2	86	32	(	(	-LRB-
cord-313312-h607itv2	86	33	TIV	TIV	NNP
cord-313312-h607itv2	86	34	)	)	-RRB-
cord-313312-h607itv2	87	1	[	[	-LRB-
cord-313312-h607itv2	87	2	61	61	CD
cord-313312-h607itv2	87	3	]	]	-RRB-
cord-313312-h607itv2	87	4	.	.	.
cord-313312-h607itv2	88	1	Put	put	VB
cord-313312-h607itv2	88	2	together	together	RB
cord-313312-h607itv2	88	3	,	,	,
cord-313312-h607itv2	88	4	these	these	DT
cord-313312-h607itv2	88	5	studies	study	NNS
cord-313312-h607itv2	88	6	demonstrate	demonstrate	VBP
cord-313312-h607itv2	88	7	the	the	DT
cord-313312-h607itv2	88	8	potential	potential	NN
cord-313312-h607itv2	88	9	of	of	IN
cord-313312-h607itv2	88	10	LAIV	LAIV	NNP
cord-313312-h607itv2	88	11	as	as	IN
cord-313312-h607itv2	88	12	a	a	DT
cord-313312-h607itv2	88	13	highly	highly	RB
cord-313312-h607itv2	88	14	efficacious	efficacious	JJ
cord-313312-h607itv2	88	15	vaccine	vaccine	NN
cord-313312-h607itv2	88	16	.	.	.
cord-313312-h607itv2	89	1	Yet	yet	RB
cord-313312-h607itv2	89	2	,	,	,
cord-313312-h607itv2	89	3	efforts	effort	NNS
cord-313312-h607itv2	89	4	to	to	TO
cord-313312-h607itv2	89	5	develop	develop	VB
cord-313312-h607itv2	89	6	such	such	PDT
cord-313312-h607itv2	89	7	a	a	DT
cord-313312-h607itv2	89	8	vaccine	vaccine	NN
cord-313312-h607itv2	89	9	have	have	VBP
cord-313312-h607itv2	89	10	been	be	VBN
cord-313312-h607itv2	89	11	stymied	stymie	VBN
cord-313312-h607itv2	89	12	by	by	IN
cord-313312-h607itv2	89	13	the	the	DT
cord-313312-h607itv2	89	14	presence	presence	NN
cord-313312-h607itv2	89	15	of	of	IN
cord-313312-h607itv2	89	16	pre	pre	JJ
cord-313312-h607itv2	89	17	-	-	JJ
cord-313312-h607itv2	89	18	existing	existing	JJ
cord-313312-h607itv2	89	19	immunity	immunity	NN
cord-313312-h607itv2	89	20	gained	gain	VBD
cord-313312-h607itv2	89	21	over	over	IN
cord-313312-h607itv2	89	22	a	a	DT
cord-313312-h607itv2	89	23	lifetime	lifetime	NN
cord-313312-h607itv2	89	24	of	of	IN
cord-313312-h607itv2	89	25	exposure	exposure	NN
cord-313312-h607itv2	89	26	to	to	IN
cord-313312-h607itv2	89	27	different	different	JJ
cord-313312-h607itv2	89	28	viral	viral	JJ
cord-313312-h607itv2	89	29	strains	strain	NNS
cord-313312-h607itv2	89	30	either	either	CC
cord-313312-h607itv2	89	31	from	from	IN
cord-313312-h607itv2	89	32	natural	natural	JJ
cord-313312-h607itv2	89	33	infection	infection	NN
cord-313312-h607itv2	89	34	or	or	CC
cord-313312-h607itv2	89	35	vaccination	vaccination	NN
cord-313312-h607itv2	89	36	.	.	.
cord-313312-h607itv2	90	1	Indeed	indeed	RB
cord-313312-h607itv2	90	2	,	,	,
cord-313312-h607itv2	90	3	several	several	JJ
cord-313312-h607itv2	90	4	observational	observational	JJ
cord-313312-h607itv2	90	5	studies	study	NNS
cord-313312-h607itv2	90	6	point	point	VBP
cord-313312-h607itv2	90	7	to	to	IN
cord-313312-h607itv2	90	8	the	the	DT
cord-313312-h607itv2	90	9	possibility	possibility	NN
cord-313312-h607itv2	90	10	that	that	IN
cord-313312-h607itv2	90	11	pre	pre	JJ
cord-313312-h607itv2	90	12	-	-	JJ
cord-313312-h607itv2	90	13	existing	existing	JJ
cord-313312-h607itv2	90	14	immunity	immunity	NN
cord-313312-h607itv2	90	15	can	can	MD
cord-313312-h607itv2	90	16	reduce	reduce	VB
cord-313312-h607itv2	90	17	the	the	DT
cord-313312-h607itv2	90	18	efficacy	efficacy	NN
cord-313312-h607itv2	90	19	of	of	IN
cord-313312-h607itv2	90	20	both	both	CC
cord-313312-h607itv2	90	21	inactivated	inactivated	JJ
cord-313312-h607itv2	90	22	and	and	CC
cord-313312-h607itv2	90	23	life	life	NN
cord-313312-h607itv2	90	24	-	-	HYPH
cord-313312-h607itv2	90	25	attenuated	attenuate	VBN
cord-313312-h607itv2	90	26	influenza	influenza	NN
cord-313312-h607itv2	90	27	vaccine	vaccine	NN
cord-313312-h607itv2	90	28	[	[	-LRB-
cord-313312-h607itv2	90	29	62	62	CD
cord-313312-h607itv2	90	30	]	]	-RRB-
cord-313312-h607itv2	90	31	[	[	-LRB-
cord-313312-h607itv2	90	32	63	63	CD
cord-313312-h607itv2	90	33	]	]	-RRB-
cord-313312-h607itv2	90	34	[	[	-LRB-
cord-313312-h607itv2	90	35	64	64	CD
cord-313312-h607itv2	90	36	]	]	-RRB-
cord-313312-h607itv2	91	1	[	[	-LRB-
cord-313312-h607itv2	91	2	65	65	CD
cord-313312-h607itv2	91	3	]	]	-RRB-
cord-313312-h607itv2	92	1	[	[	-LRB-
cord-313312-h607itv2	92	2	66	66	CD
cord-313312-h607itv2	92	3	]	]	-RRB-
cord-313312-h607itv2	93	1	[	[	-LRB-
cord-313312-h607itv2	93	2	67	67	CD
cord-313312-h607itv2	93	3	]	]	-RRB-
cord-313312-h607itv2	93	4	[	[	-LRB-
cord-313312-h607itv2	93	5	68	68	CD
cord-313312-h607itv2	93	6	]	]	-RRB-
cord-313312-h607itv2	93	7	.	.	.
cord-313312-h607itv2	94	1	For	for	IN
cord-313312-h607itv2	94	2	example	example	NN
cord-313312-h607itv2	94	3	,	,	,
cord-313312-h607itv2	94	4	Saito	Saito	NNP
cord-313312-h607itv2	94	5	et	et	NNP
cord-313312-h607itv2	94	6	al	al	NNP
cord-313312-h607itv2	94	7	.	.	NNP
cord-313312-h607itv2	94	8	found	find	VBD
cord-313312-h607itv2	94	9	that	that	IN
cord-313312-h607itv2	94	10	children	child	NNS
cord-313312-h607itv2	94	11	who	who	WP
cord-313312-h607itv2	94	12	received	receive	VBD
cord-313312-h607itv2	94	13	TIV	TIV	NNP
cord-313312-h607itv2	94	14	for	for	IN
cord-313312-h607itv2	94	15	a	a	DT
cord-313312-h607itv2	94	16	previous	previous	JJ
cord-313312-h607itv2	94	17	season	season	NN
cord-313312-h607itv2	94	18	had	have	VBD
cord-313312-h607itv2	94	19	reduced	reduce	VBN
cord-313312-h607itv2	94	20	vaccine	vaccine	NN
cord-313312-h607itv2	94	21	effectiveness	effectiveness	NN
cord-313312-h607itv2	94	22	for	for	IN
cord-313312-h607itv2	94	23	the	the	DT
cord-313312-h607itv2	94	24	current	current	JJ
cord-313312-h607itv2	94	25	seasonal	seasonal	JJ
cord-313312-h607itv2	94	26	vaccine	vaccine	NN
cord-313312-h607itv2	94	27	compared	compare	VBN
cord-313312-h607itv2	94	28	to	to	IN
cord-313312-h607itv2	94	29	unvaccinated	unvaccinated	JJ
cord-313312-h607itv2	94	30	children	child	NNS
cord-313312-h607itv2	94	31	[	[	-LRB-
cord-313312-h607itv2	94	32	66	66	CD
cord-313312-h607itv2	94	33	]	]	-RRB-
cord-313312-h607itv2	94	34	.	.	.
cord-313312-h607itv2	95	1	Likewise	likewise	RB
cord-313312-h607itv2	95	2	,	,	,
cord-313312-h607itv2	95	3	Sasaki	Sasaki	NNP
cord-313312-h607itv2	95	4	et	et	NNP
cord-313312-h607itv2	95	5	al	al	NNP
cord-313312-h607itv2	95	6	.	.	.
cord-313312-h607itv2	96	1	showed	show	VBD
cord-313312-h607itv2	96	2	lower	low	JJR
cord-313312-h607itv2	96	3	antibody	antibody	NN
cord-313312-h607itv2	96	4	induction	induction	NN
cord-313312-h607itv2	96	5	by	by	IN
cord-313312-h607itv2	96	6	a	a	DT
cord-313312-h607itv2	96	7	LAIV	LAIV	NNP
cord-313312-h607itv2	96	8	in	in	IN
cord-313312-h607itv2	96	9	individuals	individual	NNS
cord-313312-h607itv2	96	10	who	who	WP
cord-313312-h607itv2	96	11	had	have	VBD
cord-313312-h607itv2	96	12	prior	prior	JJ
cord-313312-h607itv2	96	13	year	year	NN
cord-313312-h607itv2	96	14	TIV	TIV	NNP
cord-313312-h607itv2	96	15	vaccination	vaccination	NN
cord-313312-h607itv2	96	16	[	[	-LRB-
cord-313312-h607itv2	96	17	67	67	CD
cord-313312-h607itv2	96	18	]	]	-RRB-
cord-313312-h607itv2	96	19	.	.	.
cord-313312-h607itv2	97	1	Furthermore	furthermore	RB
cord-313312-h607itv2	97	2	,	,	,
cord-313312-h607itv2	97	3	Coelingh	Coelingh	NNP
cord-313312-h607itv2	97	4	et	et	NNP
cord-313312-h607itv2	97	5	al	al	NNP
cord-313312-h607itv2	97	6	.	.	NNP
cord-313312-h607itv2	97	7	demonstrated	demonstrate	VBD
cord-313312-h607itv2	97	8	that	that	IN
cord-313312-h607itv2	97	9	younger	young	JJR
cord-313312-h607itv2	97	10	children	child	NNS
cord-313312-h607itv2	97	11	aged	age	VBN
cord-313312-h607itv2	97	12	two	two	CD
cord-313312-h607itv2	97	13	to	to	TO
cord-313312-h607itv2	97	14	eight	eight	CD
cord-313312-h607itv2	97	15	as	as	RB
cord-313312-h607itv2	97	16	well	well	RB
cord-313312-h607itv2	97	17	as	as	IN
cord-313312-h607itv2	97	18	baseline	baseline	JJ
cord-313312-h607itv2	97	19	seronegative	seronegative	JJ
cord-313312-h607itv2	97	20	adults	adult	NNS
cord-313312-h607itv2	97	21	had	have	VBD
cord-313312-h607itv2	97	22	higher	high	JJR
cord-313312-h607itv2	97	23	fold	fold	NN
cord-313312-h607itv2	97	24	-	-	HYPH
cord-313312-h607itv2	97	25	induction	induction	NN
cord-313312-h607itv2	97	26	of	of	IN
cord-313312-h607itv2	97	27	serum	serum	NN
cord-313312-h607itv2	97	28	hemagglutinin	hemagglutinin	NN
cord-313312-h607itv2	97	29	inhibition	inhibition	NN
cord-313312-h607itv2	97	30	(	(	-LRB-
cord-313312-h607itv2	97	31	HAI	HAI	NNP
cord-313312-h607itv2	97	32	)	)	-RRB-
cord-313312-h607itv2	97	33	antibody	antibody	NN
cord-313312-h607itv2	97	34	titers	titer	NNS
cord-313312-h607itv2	97	35	post	post	VBP
cord-313312-h607itv2	97	36	-	-	JJ
cord-313312-h607itv2	97	37	LAIV	LAIV	NNP
cord-313312-h607itv2	97	38	vaccination	vaccination	NN
cord-313312-h607itv2	97	39	[	[	-LRB-
cord-313312-h607itv2	97	40	69	69	CD
cord-313312-h607itv2	97	41	]	]	-RRB-
cord-313312-h607itv2	97	42	.	.	.
cord-313312-h607itv2	98	1	However	however	RB
cord-313312-h607itv2	98	2	,	,	,
cord-313312-h607itv2	98	3	given	give	VBN
cord-313312-h607itv2	98	4	how	how	WRB
cord-313312-h607itv2	98	5	complicated	complicated	JJ
cord-313312-h607itv2	98	6	it	-PRON-	PRP
cord-313312-h607itv2	98	7	is	be	VBZ
cord-313312-h607itv2	98	8	to	to	TO
cord-313312-h607itv2	98	9	trace	trace	VB
cord-313312-h607itv2	98	10	the	the	DT
cord-313312-h607itv2	98	11	history	history	NN
cord-313312-h607itv2	98	12	of	of	IN
cord-313312-h607itv2	98	13	an	an	DT
cord-313312-h607itv2	98	14	individual	individual	NN
cord-313312-h607itv2	98	15	's	's	POS
cord-313312-h607itv2	98	16	exposure	exposure	NN
cord-313312-h607itv2	98	17	to	to	IN
cord-313312-h607itv2	98	18	influenza	influenza	NN
cord-313312-h607itv2	98	19	strains	strain	NNS
cord-313312-h607itv2	98	20	,	,	,
cord-313312-h607itv2	98	21	it	-PRON-	PRP
cord-313312-h607itv2	98	22	is	be	VBZ
cord-313312-h607itv2	98	23	difficult	difficult	JJ
cord-313312-h607itv2	98	24	to	to	TO
cord-313312-h607itv2	98	25	tease	tease	VB
cord-313312-h607itv2	98	26	out	out	RP
cord-313312-h607itv2	98	27	the	the	DT
cord-313312-h607itv2	98	28	exact	exact	JJ
cord-313312-h607itv2	98	29	impact	impact	NN
cord-313312-h607itv2	98	30	that	that	WDT
cord-313312-h607itv2	98	31	pre	pre	JJ
cord-313312-h607itv2	98	32	-	-	JJ
cord-313312-h607itv2	98	33	existing	existing	JJ
cord-313312-h607itv2	98	34	immunity	immunity	NN
cord-313312-h607itv2	98	35	has	have	VBZ
cord-313312-h607itv2	98	36	on	on	IN
cord-313312-h607itv2	98	37	vaccine	vaccine	NN
cord-313312-h607itv2	98	38	efficacy	efficacy	NN
cord-313312-h607itv2	98	39	in	in	IN
cord-313312-h607itv2	98	40	human	human	JJ
cord-313312-h607itv2	98	41	samples	sample	NNS
cord-313312-h607itv2	98	42	.	.	.
cord-313312-h607itv2	99	1	Perhaps	perhaps	RB
cord-313312-h607itv2	99	2	then	then	RB
cord-313312-h607itv2	99	3	,	,	,
cord-313312-h607itv2	99	4	by	by	IN
cord-313312-h607itv2	99	5	establishing	establish	VBG
cord-313312-h607itv2	99	6	a	a	DT
cord-313312-h607itv2	99	7	good	good	JJ
cord-313312-h607itv2	99	8	animal	animal	NN
cord-313312-h607itv2	99	9	model	model	NN
cord-313312-h607itv2	99	10	with	with	IN
cord-313312-h607itv2	99	11	controlled	control	VBN
cord-313312-h607itv2	99	12	infection	infection	NN
cord-313312-h607itv2	99	13	histories	history	NNS
cord-313312-h607itv2	99	14	,	,	,
cord-313312-h607itv2	99	15	we	-PRON-	PRP
cord-313312-h607itv2	99	16	will	will	MD
cord-313312-h607itv2	99	17	be	be	VB
cord-313312-h607itv2	99	18	able	able	JJ
cord-313312-h607itv2	99	19	to	to	TO
cord-313312-h607itv2	99	20	better	well	RBR
cord-313312-h607itv2	99	21	understand	understand	VB
cord-313312-h607itv2	99	22	these	these	DT
cord-313312-h607itv2	99	23	complexities	complexity	NNS
cord-313312-h607itv2	99	24	.	.	.
cord-313312-h607itv2	100	1	Flaviviruses	flavivirus	NNS
cord-313312-h607itv2	100	2	include	include	VBP
cord-313312-h607itv2	100	3	a	a	DT
cord-313312-h607itv2	100	4	number	number	NN
cord-313312-h607itv2	100	5	of	of	IN
cord-313312-h607itv2	100	6	clinically	clinically	RB
cord-313312-h607itv2	100	7	important	important	JJ
cord-313312-h607itv2	100	8	pathogens	pathogen	NNS
cord-313312-h607itv2	100	9	that	that	WDT
cord-313312-h607itv2	100	10	are	be	VBP
cord-313312-h607itv2	100	11	either	either	RB
cord-313312-h607itv2	100	12	transmitted	transmit	VBN
cord-313312-h607itv2	100	13	by	by	IN
cord-313312-h607itv2	100	14	mosquitoes	mosquito	NNS
cord-313312-h607itv2	100	15	(	(	-LRB-
cord-313312-h607itv2	100	16	dengue	dengue	NN
cord-313312-h607itv2	100	17	,	,	,
cord-313312-h607itv2	100	18	Zika	Zika	NNP
cord-313312-h607itv2	100	19	,	,	,
cord-313312-h607itv2	100	20	yellow	yellow	JJ
cord-313312-h607itv2	100	21	fever	fever	NN
cord-313312-h607itv2	100	22	,	,	,
cord-313312-h607itv2	100	23	West	West	NNP
cord-313312-h607itv2	100	24	Nile	Nile	NNP
cord-313312-h607itv2	100	25	,	,	,
cord-313312-h607itv2	100	26	and	and	CC
cord-313312-h607itv2	100	27	Japanese	japanese	JJ
cord-313312-h607itv2	100	28	encephalitis	encephalitis	NN
cord-313312-h607itv2	100	29	virus	virus	NN
cord-313312-h607itv2	100	30	)	)	-RRB-
cord-313312-h607itv2	100	31	or	or	CC
cord-313312-h607itv2	100	32	by	by	IN
cord-313312-h607itv2	100	33	ticks	tick	NNS
cord-313312-h607itv2	100	34	(	(	-LRB-
cord-313312-h607itv2	100	35	tick	tick	VB
cord-313312-h607itv2	100	36	-	-	HYPH
cord-313312-h607itv2	100	37	borne	bear	VBN
cord-313312-h607itv2	100	38	encephalitis	encephalitis	RB
cord-313312-h607itv2	100	39	,	,	,
cord-313312-h607itv2	100	40	Powassan	Powassan	NNP
cord-313312-h607itv2	100	41	virus	virus	NN
cord-313312-h607itv2	100	42	)	)	-RRB-
cord-313312-h607itv2	100	43	[	[	-LRB-
cord-313312-h607itv2	100	44	70	70	CD
cord-313312-h607itv2	100	45	]	]	-RRB-
cord-313312-h607itv2	100	46	.	.	.
cord-313312-h607itv2	101	1	The	the	DT
cord-313312-h607itv2	101	2	recent	recent	JJ
cord-313312-h607itv2	101	3	Zika	Zika	NNP
cord-313312-h607itv2	101	4	pandemic	pandemic	NN
cord-313312-h607itv2	101	5	witnessed	witness	VBD
cord-313312-h607itv2	101	6	more	more	JJR
cord-313312-h607itv2	101	7	than	than	IN
cord-313312-h607itv2	101	8	3700	3700	CD
cord-313312-h607itv2	101	9	cases	case	NNS
cord-313312-h607itv2	101	10	of	of	IN
cord-313312-h607itv2	101	11	congenital	congenital	JJ
cord-313312-h607itv2	101	12	birth	birth	NN
cord-313312-h607itv2	101	13	defects	defect	NNS
cord-313312-h607itv2	101	14	linked	link	VBN
cord-313312-h607itv2	101	15	to	to	IN
cord-313312-h607itv2	101	16	Zika	Zika	NNP
cord-313312-h607itv2	101	17	virus	virus	NN
cord-313312-h607itv2	101	18	infection	infection	NN
cord-313312-h607itv2	101	19	in	in	IN
cord-313312-h607itv2	101	20	the	the	DT
cord-313312-h607itv2	101	21	Americas	Americas	NNPS
cord-313312-h607itv2	101	22	and	and	CC
cord-313312-h607itv2	101	23	was	be	VBD
cord-313312-h607itv2	101	24	declared	declare	VBN
cord-313312-h607itv2	101	25	by	by	IN
cord-313312-h607itv2	101	26	the	the	DT
cord-313312-h607itv2	101	27	World	World	NNP
cord-313312-h607itv2	101	28	Health	Health	NNP
cord-313312-h607itv2	101	29	Organization	Organization	NNP
cord-313312-h607itv2	101	30	in	in	IN
cord-313312-h607itv2	101	31	February	February	NNP
cord-313312-h607itv2	101	32	2016	2016	CD
cord-313312-h607itv2	101	33	to	to	TO
cord-313312-h607itv2	101	34	be	be	VB
cord-313312-h607itv2	101	35	a	a	DT
cord-313312-h607itv2	101	36	public	public	JJ
cord-313312-h607itv2	101	37	health	health	NN
cord-313312-h607itv2	101	38	emergency	emergency	NN
cord-313312-h607itv2	101	39	[	[	-LRB-
cord-313312-h607itv2	101	40	71	71	CD
cord-313312-h607itv2	101	41	]	]	-RRB-
cord-313312-h607itv2	101	42	.	.	.
cord-313312-h607itv2	102	1	Dengue	dengue	NN
cord-313312-h607itv2	102	2	infections	infection	NNS
cord-313312-h607itv2	102	3	,	,	,
cord-313312-h607itv2	102	4	on	on	IN
cord-313312-h607itv2	102	5	the	the	DT
cord-313312-h607itv2	102	6	other	other	JJ
cord-313312-h607itv2	102	7	hand	hand	NN
cord-313312-h607itv2	102	8	,	,	,
cord-313312-h607itv2	102	9	account	account	VBP
cord-313312-h607itv2	102	10	for	for	IN
cord-313312-h607itv2	102	11	390	390	CD
cord-313312-h607itv2	102	12	million	million	CD
cord-313312-h607itv2	102	13	infections	infection	NNS
cord-313312-h607itv2	102	14	annually	annually	RB
cord-313312-h607itv2	102	15	,	,	,
cord-313312-h607itv2	102	16	of	of	IN
cord-313312-h607itv2	102	17	which	which	WDT
cord-313312-h607itv2	102	18	96	96	CD
cord-313312-h607itv2	102	19	million	million	CD
cord-313312-h607itv2	102	20	infections	infection	NNS
cord-313312-h607itv2	102	21	are	be	VBP
cord-313312-h607itv2	102	22	symptomatic	symptomatic	JJ
cord-313312-h607itv2	102	23	[	[	-LRB-
cord-313312-h607itv2	102	24	72	72	CD
cord-313312-h607itv2	102	25	]	]	-RRB-
cord-313312-h607itv2	102	26	.	.	.
cord-313312-h607itv2	103	1	The	the	DT
cord-313312-h607itv2	103	2	antigenic	antigenic	JJ
cord-313312-h607itv2	103	3	closeness	closeness	NN
cord-313312-h607itv2	103	4	between	between	IN
cord-313312-h607itv2	103	5	flaviviruses	flavivirus	NNS
cord-313312-h607itv2	103	6	is	be	VBZ
cord-313312-h607itv2	103	7	such	such	JJ
cord-313312-h607itv2	103	8	that	that	DT
cord-313312-h607itv2	103	9	infection	infection	NN
cord-313312-h607itv2	103	10	with	with	IN
cord-313312-h607itv2	103	11	one	one	CD
cord-313312-h607itv2	103	12	flavivirus	flavivirus	NN
cord-313312-h607itv2	103	13	induces	induce	VBZ
cord-313312-h607itv2	103	14	species	species	NN
cord-313312-h607itv2	103	15	-	-	HYPH
cord-313312-h607itv2	103	16	specific	specific	JJ
cord-313312-h607itv2	103	17	immunity	immunity	NN
cord-313312-h607itv2	103	18	,	,	,
cord-313312-h607itv2	103	19	as	as	RB
cord-313312-h607itv2	103	20	well	well	RB
cord-313312-h607itv2	103	21	as	as	IN
cord-313312-h607itv2	103	22	cross	cross	JJ
cord-313312-h607itv2	103	23	-	-	JJ
cord-313312-h607itv2	103	24	reactive	reactive	JJ
cord-313312-h607itv2	103	25	antibodies	antibody	NNS
cord-313312-h607itv2	103	26	against	against	IN
cord-313312-h607itv2	103	27	related	relate	VBN
cord-313312-h607itv2	103	28	serocomplexes	serocomplexe	NNS
cord-313312-h607itv2	103	29	[	[	-LRB-
cord-313312-h607itv2	103	30	73	73	CD
cord-313312-h607itv2	103	31	,	,	,
cord-313312-h607itv2	103	32	74	74	CD
cord-313312-h607itv2	103	33	]	]	-RRB-
cord-313312-h607itv2	103	34	.	.	.
cord-313312-h607itv2	104	1	However	however	RB
cord-313312-h607itv2	104	2	,	,	,
cord-313312-h607itv2	104	3	these	these	DT
cord-313312-h607itv2	104	4	cross	cross	JJ
cord-313312-h607itv2	104	5	-	-	JJ
cord-313312-h607itv2	104	6	reactive	reactive	JJ
cord-313312-h607itv2	104	7	antibodies	antibody	NNS
cord-313312-h607itv2	104	8	do	do	VBP
cord-313312-h607itv2	104	9	not	not	RB
cord-313312-h607itv2	104	10	necessarily	necessarily	RB
cord-313312-h607itv2	104	11	cross	cross	VB
cord-313312-h607itv2	104	12	-	-	JJ
cord-313312-h607itv2	104	13	protect	protect	JJ
cord-313312-h607itv2	104	14	.	.	.
cord-313312-h607itv2	105	1	Initial	initial	JJ
cord-313312-h607itv2	105	2	insights	insight	NNS
cord-313312-h607itv2	105	3	come	come	VBP
cord-313312-h607itv2	105	4	from	from	IN
cord-313312-h607itv2	105	5	human	human	JJ
cord-313312-h607itv2	105	6	dengue	dengue	NN
cord-313312-h607itv2	105	7	challenge	challenge	NN
cord-313312-h607itv2	105	8	studies	study	NNS
cord-313312-h607itv2	105	9	by	by	IN
cord-313312-h607itv2	105	10	Albert	Albert	NNP
cord-313312-h607itv2	105	11	Sabin	Sabin	NNP
cord-313312-h607itv2	105	12	,	,	,
cord-313312-h607itv2	105	13	who	who	WP
cord-313312-h607itv2	105	14	provided	provide	VBD
cord-313312-h607itv2	105	15	evidence	evidence	NN
cord-313312-h607itv2	105	16	that	that	IN
cord-313312-h607itv2	105	17	a	a	DT
cord-313312-h607itv2	105	18	homologous	homologous	JJ
cord-313312-h607itv2	105	19	challenge	challenge	NN
cord-313312-h607itv2	105	20	in	in	IN
cord-313312-h607itv2	105	21	humans	human	NNS
cord-313312-h607itv2	105	22	with	with	IN
cord-313312-h607itv2	105	23	the	the	DT
cord-313312-h607itv2	105	24	same	same	JJ
cord-313312-h607itv2	105	25	dengue	dengue	NN
cord-313312-h607itv2	105	26	virus	virus	NN
cord-313312-h607itv2	105	27	(	(	-LRB-
cord-313312-h607itv2	105	28	DENV	DENV	NNP
cord-313312-h607itv2	105	29	)	)	-RRB-
cord-313312-h607itv2	105	30	serotype	serotype	NN
cord-313312-h607itv2	105	31	protects	protect	VBZ
cord-313312-h607itv2	105	32	against	against	IN
cord-313312-h607itv2	105	33	re	re	NN
cord-313312-h607itv2	105	34	-	-	NN
cord-313312-h607itv2	105	35	infection	infection	NN
cord-313312-h607itv2	105	36	,	,	,
cord-313312-h607itv2	105	37	but	but	CC
cord-313312-h607itv2	105	38	only	only	RB
cord-313312-h607itv2	105	39	short	short	JJ
cord-313312-h607itv2	105	40	-	-	HYPH
cord-313312-h607itv2	105	41	term	term	NN
cord-313312-h607itv2	105	42	protection	protection	NN
cord-313312-h607itv2	105	43	against	against	IN
cord-313312-h607itv2	105	44	the	the	DT
cord-313312-h607itv2	105	45	heterologous	heterologous	NNP
cord-313312-h607itv2	105	46	DENV	DENV	NNP
cord-313312-h607itv2	105	47	serotype	serotype	NN
cord-313312-h607itv2	105	48	challenge	challenge	NN
cord-313312-h607itv2	105	49	for	for	IN
cord-313312-h607itv2	105	50	up	up	IN
cord-313312-h607itv2	105	51	to	to	TO
cord-313312-h607itv2	105	52	six	six	CD
cord-313312-h607itv2	105	53	months	month	NNS
cord-313312-h607itv2	105	54	[	[	-LRB-
cord-313312-h607itv2	105	55	75	75	CD
cord-313312-h607itv2	105	56	,	,	,
cord-313312-h607itv2	105	57	76	76	CD
cord-313312-h607itv2	105	58	]	]	-RRB-
cord-313312-h607itv2	105	59	.	.	.
cord-313312-h607itv2	106	1	Moreover	moreover	RB
cord-313312-h607itv2	106	2	,	,	,
cord-313312-h607itv2	106	3	when	when	WRB
cord-313312-h607itv2	106	4	cross	cross	JJ
cord-313312-h607itv2	106	5	-	-	JJ
cord-313312-h607itv2	106	6	reactive	reactive	JJ
cord-313312-h607itv2	106	7	antibodies	antibody	NNS
cord-313312-h607itv2	106	8	decline	decline	VBP
cord-313312-h607itv2	106	9	to	to	TO
cord-313312-h607itv2	106	10	sub	sub	VB
cord-313312-h607itv2	106	11	-	-	JJ
cord-313312-h607itv2	106	12	neutralizing	neutralize	VBG
cord-313312-h607itv2	106	13	levels	level	NNS
cord-313312-h607itv2	106	14	,	,	,
cord-313312-h607itv2	106	15	these	these	DT
cord-313312-h607itv2	106	16	antibodies	antibody	NNS
cord-313312-h607itv2	106	17	can	can	MD
cord-313312-h607itv2	106	18	opsonize	opsonize	VB
cord-313312-h607itv2	106	19	dengue	dengue	NN
cord-313312-h607itv2	106	20	virus	virus	NN
cord-313312-h607itv2	106	21	infection	infection	NN
cord-313312-h607itv2	106	22	,	,	,
cord-313312-h607itv2	106	23	resulting	result	VBG
cord-313312-h607itv2	106	24	in	in	IN
cord-313312-h607itv2	106	25	enhanced	enhanced	JJ
cord-313312-h607itv2	106	26	virus	virus	NN
cord-313312-h607itv2	106	27	burden	burden	NN
cord-313312-h607itv2	106	28	and	and	CC
cord-313312-h607itv2	106	29	risk	risk	NN
cord-313312-h607itv2	106	30	of	of	IN
cord-313312-h607itv2	106	31	severe	severe	JJ
cord-313312-h607itv2	106	32	dengue	dengue	NN
cord-313312-h607itv2	106	33	in	in	IN
cord-313312-h607itv2	106	34	patients	patient	NNS
cord-313312-h607itv2	106	35	experiencing	experience	VBG
cord-313312-h607itv2	106	36	secondary	secondary	JJ
cord-313312-h607itv2	106	37	infection	infection	NN
cord-313312-h607itv2	106	38	[	[	-LRB-
cord-313312-h607itv2	106	39	77	77	CD
cord-313312-h607itv2	106	40	]	]	-RRB-
cord-313312-h607itv2	106	41	.	.	.
cord-313312-h607itv2	107	1	Indeed	indeed	RB
cord-313312-h607itv2	107	2	,	,	,
cord-313312-h607itv2	107	3	recent	recent	JJ
cord-313312-h607itv2	107	4	cohort	cohort	NN
cord-313312-h607itv2	107	5	studies	study	NNS
cord-313312-h607itv2	107	6	conducted	conduct	VBN
cord-313312-h607itv2	107	7	in	in	IN
cord-313312-h607itv2	107	8	Nicaragua	Nicaragua	NNP
cord-313312-h607itv2	107	9	and	and	CC
cord-313312-h607itv2	107	10	Thailand	Thailand	NNP
cord-313312-h607itv2	107	11	provide	provide	VBP
cord-313312-h607itv2	107	12	clinical	clinical	JJ
cord-313312-h607itv2	107	13	evidence	evidence	NN
cord-313312-h607itv2	107	14	that	that	IN
cord-313312-h607itv2	107	15	a	a	DT
cord-313312-h607itv2	107	16	specific	specific	JJ
cord-313312-h607itv2	107	17	range	range	NN
cord-313312-h607itv2	107	18	of	of	IN
cord-313312-h607itv2	107	19	antibody	antibody	NN
cord-313312-h607itv2	107	20	titers	titer	NNS
cord-313312-h607itv2	107	21	is	be	VBZ
cord-313312-h607itv2	107	22	associated	associate	VBN
cord-313312-h607itv2	107	23	with	with	IN
cord-313312-h607itv2	107	24	an	an	DT
cord-313312-h607itv2	107	25	increased	increase	VBN
cord-313312-h607itv2	107	26	risk	risk	NN
cord-313312-h607itv2	107	27	of	of	IN
cord-313312-h607itv2	107	28	severe	severe	JJ
cord-313312-h607itv2	107	29	dengue	dengue	NN
cord-313312-h607itv2	107	30	[	[	-LRB-
cord-313312-h607itv2	107	31	78	78	CD
cord-313312-h607itv2	107	32	,	,	,
cord-313312-h607itv2	107	33	79	79	CD
cord-313312-h607itv2	107	34	]	]	-RRB-
cord-313312-h607itv2	107	35	.	.	.
cord-313312-h607itv2	108	1	The	the	DT
cord-313312-h607itv2	108	2	presence	presence	NN
cord-313312-h607itv2	108	3	of	of	IN
cord-313312-h607itv2	108	4	waning	wane	VBG
cord-313312-h607itv2	108	5	maternal	maternal	JJ
cord-313312-h607itv2	108	6	anti	anti	JJ
cord-313312-h607itv2	108	7	-	-	JJ
cord-313312-h607itv2	108	8	dengue	dengue	JJ
cord-313312-h607itv2	108	9	antibodies	antibody	NNS
cord-313312-h607itv2	108	10	can	can	MD
cord-313312-h607itv2	108	11	also	also	RB
cord-313312-h607itv2	108	12	predispose	predispose	VB
cord-313312-h607itv2	108	13	children	child	NNS
cord-313312-h607itv2	108	14	to	to	TO
cord-313312-h607itv2	108	15	dengue	dengue	VB
cord-313312-h607itv2	108	16	hemorrhagic	hemorrhagic	JJ
cord-313312-h607itv2	108	17	fever	fever	NN
cord-313312-h607itv2	108	18	,	,	,
cord-313312-h607itv2	108	19	reinforcing	reinforce	VBG
cord-313312-h607itv2	108	20	the	the	DT
cord-313312-h607itv2	108	21	concept	concept	NN
cord-313312-h607itv2	108	22	that	that	IN
cord-313312-h607itv2	108	23	pre	pre	JJ
cord-313312-h607itv2	108	24	-	-	JJ
cord-313312-h607itv2	108	25	existing	existing	JJ
cord-313312-h607itv2	108	26	antibodies	antibody	NNS
cord-313312-h607itv2	108	27	can	can	MD
cord-313312-h607itv2	108	28	promote	promote	VB
cord-313312-h607itv2	108	29	disease	disease	NN
cord-313312-h607itv2	108	30	pathogenesis	pathogenesis	NN
cord-313312-h607itv2	108	31	[	[	-LRB-
cord-313312-h607itv2	108	32	80	80	CD
cord-313312-h607itv2	108	33	]	]	-RRB-
cord-313312-h607itv2	108	34	.	.	.
cord-313312-h607itv2	109	1	Consistent	consistent	JJ
cord-313312-h607itv2	109	2	with	with	IN
cord-313312-h607itv2	109	3	the	the	DT
cord-313312-h607itv2	109	4	notion	notion	NN
cord-313312-h607itv2	109	5	that	that	IN
cord-313312-h607itv2	109	6	sub	sub	NN
cord-313312-h607itv2	109	7	-	-	JJ
cord-313312-h607itv2	109	8	neutralizing	neutralize	VBG
cord-313312-h607itv2	109	9	cross	cross	JJ
cord-313312-h607itv2	109	10	-	-	JJ
cord-313312-h607itv2	109	11	reactive	reactive	JJ
cord-313312-h607itv2	109	12	antibodies	antibody	NNS
cord-313312-h607itv2	109	13	can	can	MD
cord-313312-h607itv2	109	14	promote	promote	VB
cord-313312-h607itv2	109	15	viral	viral	JJ
cord-313312-h607itv2	109	16	infection	infection	NN
cord-313312-h607itv2	109	17	,	,	,
cord-313312-h607itv2	109	18	the	the	DT
cord-313312-h607itv2	109	19	presence	presence	NN
cord-313312-h607itv2	109	20	of	of	IN
cord-313312-h607itv2	109	21	pre	pre	JJ
cord-313312-h607itv2	109	22	-	-	JJ
cord-313312-h607itv2	109	23	existing	existing	JJ
cord-313312-h607itv2	109	24	cross	cross	JJ
cord-313312-h607itv2	109	25	-	-	JJ
cord-313312-h607itv2	109	26	reactive	reactive	JJ
cord-313312-h607itv2	109	27	antibodies	antibody	NNS
cord-313312-h607itv2	109	28	can	can	MD
cord-313312-h607itv2	109	29	also	also	RB
cord-313312-h607itv2	109	30	increase	increase	VB
cord-313312-h607itv2	109	31	the	the	DT
cord-313312-h607itv2	109	32	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	109	33	of	of	IN
cord-313312-h607itv2	109	34	flaviviral	flaviviral	FW
cord-313312-h607itv2	109	35	LAVs	lav	NNS
cord-313312-h607itv2	109	36	.	.	.
cord-313312-h607itv2	110	1	As	as	IN
cord-313312-h607itv2	110	2	demonstrated	demonstrate	VBN
cord-313312-h607itv2	110	3	in	in	IN
cord-313312-h607itv2	110	4	both	both	DT
cord-313312-h607itv2	110	5	Dengvaxia	Dengvaxia	NNP
cord-313312-h607itv2	110	6	®	®	NNP
cord-313312-h607itv2	110	7	and	and	CC
cord-313312-h607itv2	110	8	Takaeda	Takaeda	NNP
cord-313312-h607itv2	110	9	®	®	POS
cord-313312-h607itv2	110	10	dengue	dengue	NN
cord-313312-h607itv2	110	11	vaccine	vaccine	NN
cord-313312-h607itv2	110	12	trials	trial	NNS
cord-313312-h607itv2	110	13	,	,	,
cord-313312-h607itv2	110	14	seropositive	seropositive	JJ
cord-313312-h607itv2	110	15	individuals	individual	NNS
cord-313312-h607itv2	110	16	produced	produce	VBD
cord-313312-h607itv2	110	17	greater	great	JJR
cord-313312-h607itv2	110	18	neutralizing	neutralize	VBG
cord-313312-h607itv2	110	19	antibody	antibody	NN
cord-313312-h607itv2	110	20	responses	response	NNS
cord-313312-h607itv2	110	21	and	and	CC
cord-313312-h607itv2	110	22	protection	protection	NN
cord-313312-h607itv2	110	23	against	against	IN
cord-313312-h607itv2	110	24	the	the	DT
cord-313312-h607itv2	110	25	wild	wild	JJ
cord-313312-h607itv2	110	26	-	-	HYPH
cord-313312-h607itv2	110	27	type	type	NN
cord-313312-h607itv2	110	28	DENV	DENV	NNP
cord-313312-h607itv2	110	29	infection	infection	NN
cord-313312-h607itv2	110	30	compared	compare	VBN
cord-313312-h607itv2	110	31	to	to	IN
cord-313312-h607itv2	110	32	seronegative	seronegative	JJ
cord-313312-h607itv2	110	33	vaccinees	vaccinee	NNS
cord-313312-h607itv2	110	34	[	[	-LRB-
cord-313312-h607itv2	110	35	19	19	CD
cord-313312-h607itv2	110	36	,	,	,
cord-313312-h607itv2	110	37	81	81	CD
cord-313312-h607itv2	110	38	,	,	,
cord-313312-h607itv2	110	39	82	82	CD
cord-313312-h607itv2	110	40	]	]	-RRB-
cord-313312-h607itv2	110	41	.	.	.
cord-313312-h607itv2	111	1	These	these	DT
cord-313312-h607itv2	111	2	studies	study	NNS
cord-313312-h607itv2	111	3	were	be	VBD
cord-313312-h607itv2	111	4	also	also	RB
cord-313312-h607itv2	111	5	supported	support	VBN
cord-313312-h607itv2	111	6	by	by	IN
cord-313312-h607itv2	111	7	in	in	IN
cord-313312-h607itv2	111	8	vivo	vivo	NNP
cord-313312-h607itv2	111	9	studies	study	NNS
cord-313312-h607itv2	111	10	showing	show	VBG
cord-313312-h607itv2	111	11	that	that	IN
cord-313312-h607itv2	111	12	sequential	sequential	JJ
cord-313312-h607itv2	111	13	immunization	immunization	NN
cord-313312-h607itv2	111	14	for	for	IN
cord-313312-h607itv2	111	15	flaviviruses	flavivirus	NNS
cord-313312-h607itv2	111	16	with	with	IN
cord-313312-h607itv2	111	17	shared	share	VBN
cord-313312-h607itv2	111	18	CD4	CD4	NNP
cord-313312-h607itv2	111	19	epitopes	epitope	NNS
cord-313312-h607itv2	111	20	that	that	WDT
cord-313312-h607itv2	111	21	could	could	MD
cord-313312-h607itv2	111	22	enhance	enhance	VB
cord-313312-h607itv2	111	23	protection	protection	NN
cord-313312-h607itv2	111	24	during	during	IN
cord-313312-h607itv2	111	25	subsequent	subsequent	JJ
cord-313312-h607itv2	111	26	heterologous	heterologous	JJ
cord-313312-h607itv2	111	27	infection	infection	NN
cord-313312-h607itv2	111	28	[	[	-LRB-
cord-313312-h607itv2	111	29	83	83	CD
cord-313312-h607itv2	111	30	]	]	-RRB-
cord-313312-h607itv2	111	31	.	.	.
cord-313312-h607itv2	112	1	However	however	RB
cord-313312-h607itv2	112	2	,	,	,
cord-313312-h607itv2	112	3	in	in	IN
cord-313312-h607itv2	112	4	another	another	DT
cord-313312-h607itv2	112	5	study	study	NN
cord-313312-h607itv2	112	6	,	,	,
cord-313312-h607itv2	112	7	pre	pre	JJ
cord-313312-h607itv2	112	8	-	-	JJ
cord-313312-h607itv2	112	9	existing	existing	JJ
cord-313312-h607itv2	112	10	antibodies	antibody	NNS
cord-313312-h607itv2	112	11	from	from	IN
cord-313312-h607itv2	112	12	yellow	yellow	JJ
cord-313312-h607itv2	112	13	fever	fever	NN
cord-313312-h607itv2	112	14	vaccination	vaccination	NN
cord-313312-h607itv2	112	15	can	can	MD
cord-313312-h607itv2	112	16	cause	cause	VB
cord-313312-h607itv2	112	17	impairment	impairment	NN
cord-313312-h607itv2	112	18	of	of	IN
cord-313312-h607itv2	112	19	neutralizing	neutralize	VBG
cord-313312-h607itv2	112	20	antibody	antibody	NN
cord-313312-h607itv2	112	21	responses	response	NNS
cord-313312-h607itv2	112	22	to	to	TO
cord-313312-h607itv2	112	23	tick	tick	VB
cord-313312-h607itv2	112	24	-	-	HYPH
cord-313312-h607itv2	112	25	borne	bear	VBN
cord-313312-h607itv2	112	26	encephalitis	encephalitis	JJ
cord-313312-h607itv2	112	27	vaccination	vaccination	NN
cord-313312-h607itv2	112	28	[	[	-LRB-
cord-313312-h607itv2	112	29	84	84	CD
cord-313312-h607itv2	112	30	]	]	-RRB-
cord-313312-h607itv2	112	31	.	.	.
cord-313312-h607itv2	113	1	The	the	DT
cord-313312-h607itv2	113	2	clinical	clinical	JJ
cord-313312-h607itv2	113	3	trial	trial	NN
cord-313312-h607itv2	113	4	finding	finding	NN
cord-313312-h607itv2	113	5	that	that	IN
cord-313312-h607itv2	113	6	subjects	subject	NNS
cord-313312-h607itv2	113	7	with	with	IN
cord-313312-h607itv2	113	8	a	a	DT
cord-313312-h607itv2	113	9	limited	limited	JJ
cord-313312-h607itv2	113	10	range	range	NN
cord-313312-h607itv2	113	11	of	of	IN
cord-313312-h607itv2	113	12	cross	cross	JJ
cord-313312-h607itv2	113	13	-	-	JJ
cord-313312-h607itv2	113	14	reactive	reactive	JJ
cord-313312-h607itv2	113	15	antibodies	antibody	NNS
cord-313312-h607itv2	113	16	from	from	IN
cord-313312-h607itv2	113	17	a	a	DT
cord-313312-h607itv2	113	18	prior	prior	JJ
cord-313312-h607itv2	113	19	Japanese	japanese	JJ
cord-313312-h607itv2	113	20	Encephalitis	Encephalitis	NNP
cord-313312-h607itv2	113	21	vaccine	vaccine	NN
cord-313312-h607itv2	113	22	were	be	VBD
cord-313312-h607itv2	113	23	able	able	JJ
cord-313312-h607itv2	113	24	to	to	TO
cord-313312-h607itv2	113	25	enhance	enhance	VB
cord-313312-h607itv2	113	26	yellow	yellow	JJ
cord-313312-h607itv2	113	27	fever	fever	NN
cord-313312-h607itv2	113	28	vaccination	vaccination	NN
cord-313312-h607itv2	113	29	,	,	,
cord-313312-h607itv2	113	30	by	by	IN
cord-313312-h607itv2	113	31	prolonging	prolong	VBG
cord-313312-h607itv2	113	32	vaccine	vaccine	NN
cord-313312-h607itv2	113	33	viremia	viremia	NN
cord-313312-h607itv2	113	34	duration	duration	NN
cord-313312-h607itv2	113	35	that	that	WDT
cord-313312-h607itv2	113	36	leads	lead	VBZ
cord-313312-h607itv2	113	37	to	to	IN
cord-313312-h607itv2	113	38	higher	high	JJR
cord-313312-h607itv2	113	39	antibody	antibody	NN
cord-313312-h607itv2	113	40	titers	titer	NNS
cord-313312-h607itv2	113	41	,	,	,
cord-313312-h607itv2	113	42	thus	thus	RB
cord-313312-h607itv2	113	43	hints	hint	VBZ
cord-313312-h607itv2	113	44	at	at	IN
cord-313312-h607itv2	113	45	the	the	DT
cord-313312-h607itv2	113	46	possibility	possibility	NN
cord-313312-h607itv2	113	47	that	that	IN
cord-313312-h607itv2	113	48	whether	whether	IN
cord-313312-h607itv2	113	49	pre	pre	JJ
cord-313312-h607itv2	113	50	-	-	JJ
cord-313312-h607itv2	113	51	existing	existing	JJ
cord-313312-h607itv2	113	52	antibodies	antibody	NNS
cord-313312-h607itv2	113	53	inhibit	inhibit	VBP
cord-313312-h607itv2	113	54	or	or	CC
cord-313312-h607itv2	113	55	augment	augment	VB
cord-313312-h607itv2	113	56	flavivirus	flavivirus	JJ
cord-313312-h607itv2	113	57	infection	infection	NN
cord-313312-h607itv2	113	58	will	will	MD
cord-313312-h607itv2	113	59	depend	depend	VB
cord-313312-h607itv2	113	60	on	on	IN
cord-313312-h607itv2	113	61	both	both	DT
cord-313312-h607itv2	113	62	antibody	antibody	NN
cord-313312-h607itv2	113	63	titers	titer	NNS
cord-313312-h607itv2	113	64	and	and	CC
cord-313312-h607itv2	113	65	the	the	DT
cord-313312-h607itv2	113	66	type	type	NN
cord-313312-h607itv2	113	67	/	/	SYM
cord-313312-h607itv2	113	68	specificity	specificity	NN
cord-313312-h607itv2	113	69	of	of	IN
cord-313312-h607itv2	113	70	antibodies	antibody	NNS
cord-313312-h607itv2	113	71	produced	produce	VBD
cord-313312-h607itv2	113	72	[	[	-LRB-
cord-313312-h607itv2	113	73	85	85	CD
cord-313312-h607itv2	113	74	]	]	-RRB-
cord-313312-h607itv2	113	75	.	.	.
cord-313312-h607itv2	114	1	The	the	DT
cord-313312-h607itv2	114	2	plausible	plausible	JJ
cord-313312-h607itv2	114	3	mechanisms	mechanism	NNS
cord-313312-h607itv2	114	4	involved	involve	VBN
cord-313312-h607itv2	114	5	are	be	VBP
cord-313312-h607itv2	114	6	as	as	RB
cord-313312-h607itv2	114	7	elaborated	elaborate	VBN
cord-313312-h607itv2	114	8	below	below	RB
cord-313312-h607itv2	114	9	.	.	.
cord-313312-h607itv2	115	1	The	the	DT
cord-313312-h607itv2	115	2	primary	primary	JJ
cord-313312-h607itv2	115	3	role	role	NN
cord-313312-h607itv2	115	4	of	of	IN
cord-313312-h607itv2	115	5	antibodies	antibody	NNS
cord-313312-h607itv2	115	6	is	be	VBZ
cord-313312-h607itv2	115	7	antigen	antigen	NN
cord-313312-h607itv2	115	8	binding	bind	VBG
cord-313312-h607itv2	115	9	and	and	CC
cord-313312-h607itv2	115	10	interacting	interact	VBG
cord-313312-h607itv2	115	11	with	with	IN
cord-313312-h607itv2	115	12	Fc	Fc	NNP
cord-313312-h607itv2	115	13	-	-	HYPH
cord-313312-h607itv2	115	14	gamma	gamma	NN
cord-313312-h607itv2	115	15	receptors	receptor	NNS
cord-313312-h607itv2	115	16	(	(	-LRB-
cord-313312-h607itv2	115	17	FcγRs	FcγRs	NNP
cord-313312-h607itv2	115	18	)	)	-RRB-
cord-313312-h607itv2	115	19	to	to	TO
cord-313312-h607itv2	115	20	modulate	modulate	VB
cord-313312-h607itv2	115	21	subsequent	subsequent	JJ
cord-313312-h607itv2	115	22	immune	immune	JJ
cord-313312-h607itv2	115	23	responses	response	NNS
cord-313312-h607itv2	115	24	.	.	.
cord-313312-h607itv2	116	1	The	the	DT
cord-313312-h607itv2	116	2	integration	integration	NN
cord-313312-h607itv2	116	3	of	of	IN
cord-313312-h607itv2	116	4	both	both	CC
cord-313312-h607itv2	116	5	activating	activate	VBG
cord-313312-h607itv2	116	6	and	and	CC
cord-313312-h607itv2	116	7	inhibiting	inhibit	VBG
cord-313312-h607itv2	116	8	signals	signal	NNS
cord-313312-h607itv2	116	9	is	be	VBZ
cord-313312-h607itv2	116	10	critical	critical	JJ
cord-313312-h607itv2	116	11	for	for	IN
cord-313312-h607itv2	116	12	the	the	DT
cord-313312-h607itv2	116	13	generation	generation	NN
cord-313312-h607itv2	116	14	of	of	IN
cord-313312-h607itv2	116	15	an	an	DT
cord-313312-h607itv2	116	16	effective	effective	JJ
cord-313312-h607itv2	116	17	immune	immune	JJ
cord-313312-h607itv2	116	18	response	response	NN
cord-313312-h607itv2	116	19	.	.	.
cord-313312-h607itv2	117	1	In	in	IN
cord-313312-h607itv2	117	2	this	this	DT
cord-313312-h607itv2	117	3	aspect	aspect	NN
cord-313312-h607itv2	117	4	,	,	,
cord-313312-h607itv2	117	5	FcγRs	FcγRs	NNP
cord-313312-h607itv2	117	6	are	be	VBP
cord-313312-h607itv2	117	7	an	an	DT
cord-313312-h607itv2	117	8	archetype	archetype	NN
cord-313312-h607itv2	117	9	of	of	IN
cord-313312-h607itv2	117	10	how	how	WRB
cord-313312-h607itv2	117	11	such	such	JJ
cord-313312-h607itv2	117	12	signals	signal	NNS
cord-313312-h607itv2	117	13	influence	influence	VBP
cord-313312-h607itv2	117	14	both	both	DT
cord-313312-h607itv2	117	15	innate	innate	JJ
cord-313312-h607itv2	117	16	and	and	CC
cord-313312-h607itv2	117	17	adaptive	adaptive	JJ
cord-313312-h607itv2	117	18	immune	immune	JJ
cord-313312-h607itv2	117	19	functions	function	NNS
cord-313312-h607itv2	117	20	.	.	.
cord-313312-h607itv2	118	1	Functionally	functionally	RB
cord-313312-h607itv2	118	2	,	,	,
cord-313312-h607itv2	118	3	FcγRs	FcγRs	NNP
cord-313312-h607itv2	118	4	can	can	MD
cord-313312-h607itv2	118	5	be	be	VB
cord-313312-h607itv2	118	6	classified	classify	VBN
cord-313312-h607itv2	118	7	into	into	IN
cord-313312-h607itv2	118	8	either	either	CC
cord-313312-h607itv2	118	9	activating	activate	VBG
cord-313312-h607itv2	118	10	or	or	CC
cord-313312-h607itv2	118	11	inhibiting	inhibit	VBG
cord-313312-h607itv2	118	12	receptors	receptor	NNS
cord-313312-h607itv2	118	13	depending	depend	VBG
cord-313312-h607itv2	118	14	on	on	IN
cord-313312-h607itv2	118	15	the	the	DT
cord-313312-h607itv2	118	16	pathway	pathway	NN
cord-313312-h607itv2	119	1	they	-PRON-	PRP
cord-313312-h607itv2	119	2	initiate	initiate	VBP
cord-313312-h607itv2	119	3	[	[	-LRB-
cord-313312-h607itv2	119	4	86	86	CD
cord-313312-h607itv2	119	5	]	]	-RRB-
cord-313312-h607itv2	119	6	.	.	.
cord-313312-h607itv2	120	1	Activating	activate	VBG
cord-313312-h607itv2	120	2	FcγRs	FcγRs	NNP
cord-313312-h607itv2	120	3	possess	possess	VBP
cord-313312-h607itv2	120	4	an	an	DT
cord-313312-h607itv2	120	5	immunoreceptor	immunoreceptor	JJ
cord-313312-h607itv2	120	6	tyrosine	tyrosine	NN
cord-313312-h607itv2	120	7	-	-	HYPH
cord-313312-h607itv2	120	8	based	base	VBN
cord-313312-h607itv2	120	9	activation	activation	NN
cord-313312-h607itv2	120	10	(	(	-LRB-
cord-313312-h607itv2	120	11	ITAM	ITAM	NNP
cord-313312-h607itv2	120	12	)	)	-RRB-
cord-313312-h607itv2	120	13	motif	motif	NN
cord-313312-h607itv2	120	14	in	in	IN
cord-313312-h607itv2	120	15	their	-PRON-	PRP$
cord-313312-h607itv2	120	16	cytosolic	cytosolic	JJ
cord-313312-h607itv2	120	17	domain	domain	NN
cord-313312-h607itv2	120	18	,	,	,
cord-313312-h607itv2	120	19	or	or	CC
cord-313312-h607itv2	120	20	in	in	IN
cord-313312-h607itv2	120	21	the	the	DT
cord-313312-h607itv2	120	22	case	case	NN
cord-313312-h607itv2	120	23	of	of	IN
cord-313312-h607itv2	120	24	FcγRI	FcγRI	NNP
cord-313312-h607itv2	120	25	and	and	CC
cord-313312-h607itv2	120	26	FcγRIIIA	FcγRIIIA	NNP
cord-313312-h607itv2	120	27	,	,	,
cord-313312-h607itv2	120	28	associate	associate	VBP
cord-313312-h607itv2	120	29	with	with	IN
cord-313312-h607itv2	120	30	an	an	DT
cord-313312-h607itv2	120	31	ITAM	ITAM	NNP
cord-313312-h607itv2	120	32	-	-	HYPH
cord-313312-h607itv2	120	33	containing	contain	VBG
cord-313312-h607itv2	120	34	γ	γ	NN
cord-313312-h607itv2	120	35	-	-	HYPH
cord-313312-h607itv2	120	36	chain	chain	NN
cord-313312-h607itv2	120	37	.	.	.
cord-313312-h607itv2	121	1	Engagement	engagement	NN
cord-313312-h607itv2	121	2	of	of	IN
cord-313312-h607itv2	121	3	activating	activate	VBG
cord-313312-h607itv2	121	4	FcγRs	FcγRs	NNP
cord-313312-h607itv2	121	5	by	by	IN
cord-313312-h607itv2	121	6	immune	immune	JJ
cord-313312-h607itv2	121	7	complexes	complex	NNS
cord-313312-h607itv2	121	8	results	result	NNS
cord-313312-h607itv2	121	9	in	in	IN
cord-313312-h607itv2	121	10	the	the	DT
cord-313312-h607itv2	121	11	phosphorylation	phosphorylation	NN
cord-313312-h607itv2	121	12	of	of	IN
cord-313312-h607itv2	121	13	the	the	DT
cord-313312-h607itv2	121	14	γ	γ	NN
cord-313312-h607itv2	121	15	-	-	HYPH
cord-313312-h607itv2	121	16	chain	chain	NN
cord-313312-h607itv2	121	17	by	by	IN
cord-313312-h607itv2	121	18	SRC	SRC	NNP
cord-313312-h607itv2	121	19	-	-	HYPH
cord-313312-h607itv2	121	20	family	family	NN
cord-313312-h607itv2	121	21	kinases	kinase	NNS
cord-313312-h607itv2	121	22	in	in	IN
cord-313312-h607itv2	121	23	order	order	NN
cord-313312-h607itv2	121	24	to	to	TO
cord-313312-h607itv2	121	25	create	create	VB
cord-313312-h607itv2	121	26	a	a	DT
cord-313312-h607itv2	121	27	docking	docking	NN
cord-313312-h607itv2	121	28	site	site	NN
cord-313312-h607itv2	121	29	for	for	IN
cord-313312-h607itv2	121	30	spleen	spleen	NN
cord-313312-h607itv2	121	31	tyrosine	tyrosine	NN
cord-313312-h607itv2	121	32	kinase	kinase	NN
cord-313312-h607itv2	121	33	(	(	-LRB-
cord-313312-h607itv2	121	34	SYK	SYK	NNP
cord-313312-h607itv2	121	35	)	)	-RRB-
cord-313312-h607itv2	121	36	.	.	.
cord-313312-h607itv2	122	1	Subsequent	subsequent	JJ
cord-313312-h607itv2	122	2	activation	activation	NN
cord-313312-h607itv2	122	3	of	of	IN
cord-313312-h607itv2	122	4	SYK	SYK	NNP
cord-313312-h607itv2	122	5	results	result	NNS
cord-313312-h607itv2	122	6	in	in	IN
cord-313312-h607itv2	122	7	a	a	DT
cord-313312-h607itv2	122	8	signaling	signal	VBG
cord-313312-h607itv2	122	9	cascade	cascade	NN
cord-313312-h607itv2	122	10	,	,	,
cord-313312-h607itv2	122	11	leading	lead	VBG
cord-313312-h607itv2	122	12	to	to	IN
cord-313312-h607itv2	122	13	the	the	DT
cord-313312-h607itv2	122	14	induction	induction	NN
cord-313312-h607itv2	122	15	of	of	IN
cord-313312-h607itv2	122	16	pro	pro	JJ
cord-313312-h607itv2	122	17	-	-	JJ
cord-313312-h607itv2	122	18	inflammatory	inflammatory	JJ
cord-313312-h607itv2	122	19	responses	response	NNS
cord-313312-h607itv2	122	20	and	and	CC
cord-313312-h607itv2	122	21	activation	activation	NN
cord-313312-h607itv2	122	22	of	of	IN
cord-313312-h607itv2	122	23	innate	innate	JJ
cord-313312-h607itv2	122	24	immune	immune	JJ
cord-313312-h607itv2	122	25	effector	effector	NN
cord-313312-h607itv2	122	26	cells	cell	NNS
cord-313312-h607itv2	122	27	[	[	-LRB-
cord-313312-h607itv2	122	28	87	87	CD
cord-313312-h607itv2	122	29	,	,	,
cord-313312-h607itv2	122	30	88	88	CD
cord-313312-h607itv2	122	31	]	]	-RRB-
cord-313312-h607itv2	122	32	.	.	.
cord-313312-h607itv2	123	1	By	by	IN
cord-313312-h607itv2	123	2	contrast	contrast	NN
cord-313312-h607itv2	123	3	,	,	,
cord-313312-h607itv2	123	4	the	the	DT
cord-313312-h607itv2	123	5	inhibitory	inhibitory	JJ
cord-313312-h607itv2	123	6	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	123	7	receptor	receptor	NN
cord-313312-h607itv2	123	8	contains	contain	VBZ
cord-313312-h607itv2	123	9	an	an	DT
cord-313312-h607itv2	123	10	immunoreceptor	immunoreceptor	JJ
cord-313312-h607itv2	123	11	tyrosine	tyrosine	NN
cord-313312-h607itv2	123	12	-	-	HYPH
cord-313312-h607itv2	123	13	based	base	VBN
cord-313312-h607itv2	123	14	inhibition	inhibition	NN
cord-313312-h607itv2	123	15	(	(	-LRB-
cord-313312-h607itv2	123	16	ITIM	ITIM	NNP
cord-313312-h607itv2	123	17	)	)	-RRB-
cord-313312-h607itv2	123	18	motif	motif	NN
cord-313312-h607itv2	123	19	within	within	IN
cord-313312-h607itv2	123	20	its	-PRON-	PRP$
cord-313312-h607itv2	123	21	intracellular	intracellular	JJ
cord-313312-h607itv2	123	22	domain	domain	NN
cord-313312-h607itv2	123	23	.	.	.
cord-313312-h607itv2	124	1	Cross	cross	NN
cord-313312-h607itv2	124	2	-	-	NN
cord-313312-h607itv2	124	3	linking	linking	NN
cord-313312-h607itv2	124	4	of	of	IN
cord-313312-h607itv2	124	5	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	124	6	enables	enable	VBZ
cord-313312-h607itv2	124	7	the	the	DT
cord-313312-h607itv2	124	8	recruitment	recruitment	NN
cord-313312-h607itv2	124	9	of	of	IN
cord-313312-h607itv2	124	10	SH2	SH2	NNP
cord-313312-h607itv2	124	11	domain	domain	NN
cord-313312-h607itv2	124	12	-	-	HYPH
cord-313312-h607itv2	124	13	containing	contain	VBG
cord-313312-h607itv2	124	14	inositol	inositol	NN
cord-313312-h607itv2	124	15	polyphosphate	polyphosphate	NN
cord-313312-h607itv2	124	16	5	5	CD
cord-313312-h607itv2	124	17	phosphatase	phosphatase	NN
cord-313312-h607itv2	124	18	(	(	-LRB-
cord-313312-h607itv2	124	19	SHIP	ship	NN
cord-313312-h607itv2	124	20	)	)	-RRB-
cord-313312-h607itv2	124	21	and	and	CC
cord-313312-h607itv2	124	22	SH2	SH2	NNP
cord-313312-h607itv2	124	23	domain	domain	NN
cord-313312-h607itv2	124	24	-	-	HYPH
cord-313312-h607itv2	124	25	containing	contain	VBG
cord-313312-h607itv2	124	26	protein	protein	NN
cord-313312-h607itv2	124	27	tyrosine	tyrosine	NN
cord-313312-h607itv2	124	28	phosphatase	phosphatase	NN
cord-313312-h607itv2	124	29	1	1	CD
cord-313312-h607itv2	124	30	(	(	-LRB-
cord-313312-h607itv2	124	31	SHP1	SHP1	NNP
cord-313312-h607itv2	124	32	)	)	-RRB-
cord-313312-h607itv2	124	33	to	to	TO
cord-313312-h607itv2	124	34	modulate	modulate	VB
cord-313312-h607itv2	124	35	signals	signal	NNS
cord-313312-h607itv2	124	36	generated	generate	VBN
cord-313312-h607itv2	124	37	by	by	IN
cord-313312-h607itv2	124	38	activating	activate	VBG
cord-313312-h607itv2	124	39	FcγRs	FcγRs	NNP
cord-313312-h607itv2	124	40	,	,	,
cord-313312-h607itv2	124	41	thereby	thereby	RB
cord-313312-h607itv2	124	42	regulating	regulate	VBG
cord-313312-h607itv2	124	43	the	the	DT
cord-313312-h607itv2	124	44	magnitude	magnitude	NN
cord-313312-h607itv2	124	45	of	of	IN
cord-313312-h607itv2	124	46	inflammatory	inflammatory	JJ
cord-313312-h607itv2	124	47	responses	response	NNS
cord-313312-h607itv2	124	48	.	.	.
cord-313312-h607itv2	125	1	Furthermore	furthermore	RB
cord-313312-h607itv2	125	2	,	,	,
cord-313312-h607itv2	125	3	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	125	4	is	be	VBZ
cord-313312-h607itv2	125	5	important	important	JJ
cord-313312-h607itv2	125	6	for	for	IN
cord-313312-h607itv2	125	7	controlling	control	VBG
cord-313312-h607itv2	125	8	B	b	NN
cord-313312-h607itv2	125	9	-	-	HYPH
cord-313312-h607itv2	125	10	cell	cell	NN
cord-313312-h607itv2	125	11	development	development	NN
cord-313312-h607itv2	125	12	[	[	-LRB-
cord-313312-h607itv2	125	13	89	89	CD
cord-313312-h607itv2	125	14	]	]	-RRB-
cord-313312-h607itv2	126	1	[	[	-LRB-
cord-313312-h607itv2	126	2	90	90	CD
cord-313312-h607itv2	126	3	]	]	-RRB-
cord-313312-h607itv2	126	4	[	[	-LRB-
cord-313312-h607itv2	126	5	91	91	CD
cord-313312-h607itv2	126	6	]	]	-RRB-
cord-313312-h607itv2	126	7	[	[	-LRB-
cord-313312-h607itv2	126	8	92	92	CD
cord-313312-h607itv2	126	9	]	]	-RRB-
cord-313312-h607itv2	127	1	[	[	-LRB-
cord-313312-h607itv2	127	2	93	93	CD
cord-313312-h607itv2	127	3	]	]	-RRB-
cord-313312-h607itv2	127	4	[	[	-LRB-
cord-313312-h607itv2	127	5	94	94	CD
cord-313312-h607itv2	127	6	]	]	-RRB-
cord-313312-h607itv2	127	7	.	.	.
cord-313312-h607itv2	128	1	Indeed	indeed	RB
cord-313312-h607itv2	128	2	,	,	,
cord-313312-h607itv2	128	3	B	b	NN
cord-313312-h607itv2	128	4	-	-	HYPH
cord-313312-h607itv2	128	5	cells	cell	NNS
cord-313312-h607itv2	128	6	express	express	VBP
cord-313312-h607itv2	128	7	FcγRIIB	fcγriib	NN
cord-313312-h607itv2	128	8	as	as	IN
cord-313312-h607itv2	128	9	the	the	DT
cord-313312-h607itv2	128	10	only	only	JJ
cord-313312-h607itv2	128	11	FcγR	fcγr	NN
cord-313312-h607itv2	128	12	on	on	IN
cord-313312-h607itv2	128	13	their	-PRON-	PRP$
cord-313312-h607itv2	128	14	cell	cell	NN
cord-313312-h607itv2	128	15	surface	surface	NN
cord-313312-h607itv2	128	16	,	,	,
cord-313312-h607itv2	128	17	and	and	CC
cord-313312-h607itv2	128	18	cross	cross	NN
cord-313312-h607itv2	128	19	-	-	NN
cord-313312-h607itv2	128	20	linking	linking	NN
cord-313312-h607itv2	128	21	of	of	IN
cord-313312-h607itv2	128	22	FcγRIIB	fcγriib	NN
cord-313312-h607itv2	128	23	on	on	IN
cord-313312-h607itv2	128	24	naïve	naïve	JJ
cord-313312-h607itv2	128	25	B	b	NN
cord-313312-h607itv2	128	26	-	-	HYPH
cord-313312-h607itv2	128	27	cells	cell	NNS
cord-313312-h607itv2	128	28	could	could	MD
cord-313312-h607itv2	128	29	inhibit	inhibit	VB
cord-313312-h607itv2	128	30	their	-PRON-	PRP$
cord-313312-h607itv2	128	31	proliferation	proliferation	NN
cord-313312-h607itv2	128	32	and	and	CC
cord-313312-h607itv2	128	33	differentiation	differentiation	NN
cord-313312-h607itv2	128	34	into	into	IN
cord-313312-h607itv2	128	35	plasma	plasma	NN
cord-313312-h607itv2	128	36	cells	cell	NNS
cord-313312-h607itv2	128	37	[	[	-LRB-
cord-313312-h607itv2	128	38	95	95	CD
cord-313312-h607itv2	128	39	]	]	-RRB-
cord-313312-h607itv2	128	40	.	.	.
cord-313312-h607itv2	129	1	Likewise	likewise	RB
cord-313312-h607itv2	129	2	,	,	,
cord-313312-h607itv2	129	3	cross	cross	NN
cord-313312-h607itv2	129	4	-	-	NN
cord-313312-h607itv2	129	5	linking	linking	NN
cord-313312-h607itv2	129	6	of	of	IN
cord-313312-h607itv2	129	7	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	129	8	induces	induce	VBZ
cord-313312-h607itv2	129	9	apoptosis	apoptosis	NN
cord-313312-h607itv2	129	10	in	in	IN
cord-313312-h607itv2	129	11	bone	bone	NN
cord-313312-h607itv2	129	12	marrow	marrow	NN
cord-313312-h607itv2	129	13	plasma	plasma	NN
cord-313312-h607itv2	129	14	cells	cell	NNS
cord-313312-h607itv2	129	15	,	,	,
cord-313312-h607itv2	129	16	suggesting	suggest	VBG
cord-313312-h607itv2	129	17	that	that	IN
cord-313312-h607itv2	129	18	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	129	19	may	may	MD
cord-313312-h607itv2	129	20	influence	influence	VB
cord-313312-h607itv2	129	21	the	the	DT
cord-313312-h607itv2	129	22	lifespan	lifespan	NN
cord-313312-h607itv2	129	23	of	of	IN
cord-313312-h607itv2	129	24	these	these	DT
cord-313312-h607itv2	129	25	antibody	antibody	NN
cord-313312-h607itv2	129	26	-	-	HYPH
cord-313312-h607itv2	129	27	producing	produce	VBG
cord-313312-h607itv2	129	28	cells	cell	NNS
cord-313312-h607itv2	129	29	[	[	-LRB-
cord-313312-h607itv2	129	30	89	89	CD
cord-313312-h607itv2	129	31	]	]	-RRB-
cord-313312-h607itv2	129	32	.	.	.
cord-313312-h607itv2	130	1	The	the	DT
cord-313312-h607itv2	130	2	signaling	signal	VBG
cord-313312-h607itv2	130	3	responses	response	NNS
cord-313312-h607itv2	130	4	triggered	trigger	VBN
cord-313312-h607itv2	130	5	by	by	IN
cord-313312-h607itv2	130	6	virus	virus	NN
cord-313312-h607itv2	130	7	-	-	HYPH
cord-313312-h607itv2	130	8	antibody	antibody	NN
cord-313312-h607itv2	130	9	complexes	complex	NNS
cord-313312-h607itv2	130	10	are	be	VBP
cord-313312-h607itv2	130	11	thus	thus	RB
cord-313312-h607itv2	130	12	highly	highly	RB
cord-313312-h607itv2	130	13	dependent	dependent	JJ
cord-313312-h607itv2	130	14	on	on	IN
cord-313312-h607itv2	130	15	the	the	DT
cord-313312-h607itv2	130	16	type	type	NN
cord-313312-h607itv2	130	17	of	of	IN
cord-313312-h607itv2	130	18	FcγRs	FcγRs	NNP
cord-313312-h607itv2	130	19	with	with	IN
cord-313312-h607itv2	130	20	which	which	WDT
cord-313312-h607itv2	130	21	the	the	DT
cord-313312-h607itv2	130	22	immune	immune	JJ
cord-313312-h607itv2	130	23	complexes	complex	NNS
cord-313312-h607itv2	130	24	interact	interact	VBP
cord-313312-h607itv2	130	25	,	,	,
cord-313312-h607itv2	130	26	which	which	WDT
cord-313312-h607itv2	130	27	can	can	MD
cord-313312-h607itv2	130	28	result	result	VB
cord-313312-h607itv2	130	29	in	in	IN
cord-313312-h607itv2	130	30	either	either	DT
cord-313312-h607itv2	130	31	virus	virus	NN
cord-313312-h607itv2	130	32	inhibition	inhibition	NN
cord-313312-h607itv2	130	33	or	or	CC
cord-313312-h607itv2	130	34	enhancement	enhancement	NN
cord-313312-h607itv2	130	35	of	of	IN
cord-313312-h607itv2	130	36	virus	virus	NN
cord-313312-h607itv2	130	37	infection	infection	NN
cord-313312-h607itv2	130	38	.	.	.
cord-313312-h607itv2	131	1	Virus	virus	NN
cord-313312-h607itv2	131	2	neutralization	neutralization	NN
cord-313312-h607itv2	131	3	occurs	occur	VBZ
cord-313312-h607itv2	131	4	when	when	WRB
cord-313312-h607itv2	131	5	virions	virion	NNS
cord-313312-h607itv2	131	6	are	be	VBP
cord-313312-h607itv2	131	7	bound	bind	VBN
cord-313312-h607itv2	131	8	by	by	IN
cord-313312-h607itv2	131	9	antibodies	antibody	NNS
cord-313312-h607itv2	131	10	with	with	IN
cord-313312-h607itv2	131	11	stoichiometry	stoichiometry	NN
cord-313312-h607itv2	131	12	exceeding	exceed	VBG
cord-313312-h607itv2	131	13	a	a	DT
cord-313312-h607itv2	131	14	required	require	VBN
cord-313312-h607itv2	131	15	threshold	threshold	NN
cord-313312-h607itv2	131	16	.	.	.
cord-313312-h607itv2	132	1	Hence	hence	RB
cord-313312-h607itv2	132	2	,	,	,
cord-313312-h607itv2	132	3	one	one	CD
cord-313312-h607itv2	132	4	of	of	IN
cord-313312-h607itv2	132	5	the	the	DT
cord-313312-h607itv2	132	6	popular	popular	JJ
cord-313312-h607itv2	132	7	explanations	explanation	NNS
cord-313312-h607itv2	132	8	to	to	TO
cord-313312-h607itv2	132	9	explain	explain	VB
cord-313312-h607itv2	132	10	the	the	DT
cord-313312-h607itv2	132	11	lack	lack	NN
cord-313312-h607itv2	132	12	of	of	IN
cord-313312-h607itv2	132	13	LAV	LAV	NNP
cord-313312-h607itv2	132	14	efficacy	efficacy	NN
cord-313312-h607itv2	132	15	in	in	IN
cord-313312-h607itv2	132	16	the	the	DT
cord-313312-h607itv2	132	17	presence	presence	NN
cord-313312-h607itv2	132	18	of	of	IN
cord-313312-h607itv2	132	19	pre	pre	JJ
cord-313312-h607itv2	132	20	-	-	JJ
cord-313312-h607itv2	132	21	existing	existing	JJ
cord-313312-h607itv2	132	22	antibodies	antibody	NNS
cord-313312-h607itv2	132	23	is	be	VBZ
cord-313312-h607itv2	132	24	the	the	DT
cord-313312-h607itv2	132	25	neutralization	neutralization	NN
cord-313312-h607itv2	132	26	of	of	IN
cord-313312-h607itv2	132	27	the	the	DT
cord-313312-h607itv2	132	28	LAV	LAV	NNP
cord-313312-h607itv2	132	29	,	,	,
cord-313312-h607itv2	132	30	which	which	WDT
cord-313312-h607itv2	132	31	could	could	MD
cord-313312-h607itv2	132	32	consequently	consequently	RB
cord-313312-h607itv2	132	33	decrease	decrease	VB
cord-313312-h607itv2	132	34	the	the	DT
cord-313312-h607itv2	132	35	amount	amount	NN
cord-313312-h607itv2	132	36	of	of	IN
cord-313312-h607itv2	132	37	viral	viral	JJ
cord-313312-h607itv2	132	38	antigens	antigen	NNS
cord-313312-h607itv2	132	39	to	to	IN
cord-313312-h607itv2	132	40	levels	level	NNS
cord-313312-h607itv2	132	41	that	that	WDT
cord-313312-h607itv2	132	42	are	be	VBP
cord-313312-h607itv2	132	43	below	below	IN
cord-313312-h607itv2	132	44	the	the	DT
cord-313312-h607itv2	132	45	threshold	threshold	NN
cord-313312-h607itv2	132	46	for	for	IN
cord-313312-h607itv2	132	47	immune	immune	JJ
cord-313312-h607itv2	132	48	detection	detection	NN
cord-313312-h607itv2	132	49	and	and	CC
cord-313312-h607itv2	132	50	recognition	recognition	NN
cord-313312-h607itv2	132	51	.	.	.
cord-313312-h607itv2	133	1	Antibody	antibody	NN
cord-313312-h607itv2	133	2	concentrations	concentration	NNS
cord-313312-h607itv2	133	3	,	,	,
cord-313312-h607itv2	133	4	affinity	affinity	NN
cord-313312-h607itv2	133	5	,	,	,
cord-313312-h607itv2	133	6	and	and	CC
cord-313312-h607itv2	133	7	epitope	epitope	NN
cord-313312-h607itv2	133	8	accessibility	accessibility	NN
cord-313312-h607itv2	133	9	are	be	VBP
cord-313312-h607itv2	133	10	critical	critical	JJ
cord-313312-h607itv2	133	11	determinants	determinant	NNS
cord-313312-h607itv2	133	12	for	for	IN
cord-313312-h607itv2	133	13	virus	virus	NN
cord-313312-h607itv2	133	14	neutralization	neutralization	NN
cord-313312-h607itv2	133	15	[	[	-LRB-
cord-313312-h607itv2	133	16	96	96	CD
cord-313312-h607itv2	133	17	]	]	-RRB-
cord-313312-h607itv2	134	1	[	[	-LRB-
cord-313312-h607itv2	134	2	97	97	CD
cord-313312-h607itv2	134	3	]	]	-RRB-
cord-313312-h607itv2	134	4	[	[	-LRB-
cord-313312-h607itv2	134	5	98	98	CD
cord-313312-h607itv2	134	6	]	]	-RRB-
cord-313312-h607itv2	134	7	.	.	.
cord-313312-h607itv2	135	1	Antibody	antibody	NN
cord-313312-h607itv2	135	2	affinity	affinity	NN
cord-313312-h607itv2	135	3	,	,	,
cord-313312-h607itv2	135	4	defined	define	VBN
cord-313312-h607itv2	135	5	as	as	IN
cord-313312-h607itv2	135	6	the	the	DT
cord-313312-h607itv2	135	7	fraction	fraction	NN
cord-313312-h607itv2	135	8	of	of	IN
cord-313312-h607itv2	135	9	epitopes	epitope	NNS
cord-313312-h607itv2	135	10	that	that	WDT
cord-313312-h607itv2	135	11	are	be	VBP
cord-313312-h607itv2	135	12	bound	bind	VBN
cord-313312-h607itv2	135	13	by	by	IN
cord-313312-h607itv2	135	14	antibodies	antibody	NNS
cord-313312-h607itv2	135	15	at	at	IN
cord-313312-h607itv2	135	16	non	non	JJ
cord-313312-h607itv2	135	17	-	-	JJ
cord-313312-h607itv2	135	18	saturating	saturating	JJ
cord-313312-h607itv2	135	19	concentrations	concentration	NNS
cord-313312-h607itv2	135	20	,	,	,
cord-313312-h607itv2	135	21	has	have	VBZ
cord-313312-h607itv2	135	22	been	be	VBN
cord-313312-h607itv2	135	23	shown	show	VBN
cord-313312-h607itv2	135	24	to	to	TO
cord-313312-h607itv2	135	25	correlate	correlate	VB
cord-313312-h607itv2	135	26	with	with	IN
cord-313312-h607itv2	135	27	neutralizing	neutralize	VBG
cord-313312-h607itv2	135	28	activity	activity	NN
cord-313312-h607itv2	135	29	in	in	IN
cord-313312-h607itv2	135	30	vitro	vitro	FW
cord-313312-h607itv2	135	31	.	.	.
cord-313312-h607itv2	136	1	On	on	IN
cord-313312-h607itv2	136	2	the	the	DT
cord-313312-h607itv2	136	3	other	other	JJ
cord-313312-h607itv2	136	4	hand	hand	NN
cord-313312-h607itv2	136	5	,	,	,
cord-313312-h607itv2	136	6	epitope	epitope	NN
cord-313312-h607itv2	136	7	accessibility	accessibility	NN
cord-313312-h607itv2	136	8	is	be	VBZ
cord-313312-h607itv2	136	9	defined	define	VBN
cord-313312-h607itv2	136	10	as	as	IN
cord-313312-h607itv2	136	11	the	the	DT
cord-313312-h607itv2	136	12	number	number	NN
cord-313312-h607itv2	136	13	of	of	IN
cord-313312-h607itv2	136	14	epitopes	epitope	NNS
cord-313312-h607itv2	136	15	on	on	IN
cord-313312-h607itv2	136	16	viruses	virus	NNS
cord-313312-h607itv2	136	17	that	that	WDT
cord-313312-h607itv2	136	18	are	be	VBP
cord-313312-h607itv2	136	19	available	available	JJ
cord-313312-h607itv2	136	20	for	for	IN
cord-313312-h607itv2	136	21	binding	bind	VBG
cord-313312-h607itv2	136	22	and	and	CC
cord-313312-h607itv2	136	23	can	can	MD
cord-313312-h607itv2	136	24	be	be	VB
cord-313312-h607itv2	136	25	affected	affect	VBN
cord-313312-h607itv2	136	26	by	by	IN
cord-313312-h607itv2	136	27	virus	virus	NN
cord-313312-h607itv2	136	28	structure	structure	NN
cord-313312-h607itv2	136	29	,	,	,
cord-313312-h607itv2	136	30	structural	structural	JJ
cord-313312-h607itv2	136	31	dynamics	dynamic	NNS
cord-313312-h607itv2	136	32	of	of	IN
cord-313312-h607itv2	136	33	virus	virus	NN
cord-313312-h607itv2	136	34	,	,	,
cord-313312-h607itv2	136	35	and	and	CC
cord-313312-h607itv2	136	36	virus	virus	NN
cord-313312-h607itv2	136	37	maturation	maturation	NN
cord-313312-h607itv2	136	38	states	state	NNS
cord-313312-h607itv2	136	39	[	[	-LRB-
cord-313312-h607itv2	136	40	99	99	CD
cord-313312-h607itv2	136	41	]	]	-RRB-
cord-313312-h607itv2	136	42	.	.	.
cord-313312-h607itv2	137	1	The	the	DT
cord-313312-h607itv2	137	2	epitope	epitope	NN
cord-313312-h607itv2	137	3	availability	availability	NN
cord-313312-h607itv2	137	4	would	would	MD
cord-313312-h607itv2	137	5	thus	thus	RB
cord-313312-h607itv2	137	6	affect	affect	VB
cord-313312-h607itv2	137	7	the	the	DT
cord-313312-h607itv2	137	8	fraction	fraction	NN
cord-313312-h607itv2	137	9	of	of	IN
cord-313312-h607itv2	137	10	epitope	epitope	NN
cord-313312-h607itv2	137	11	occupancy	occupancy	NN
cord-313312-h607itv2	137	12	that	that	WDT
cord-313312-h607itv2	137	13	will	will	MD
cord-313312-h607itv2	137	14	be	be	VB
cord-313312-h607itv2	137	15	required	require	VBN
cord-313312-h607itv2	137	16	for	for	IN
cord-313312-h607itv2	137	17	virus	virus	NN
cord-313312-h607itv2	137	18	neutralization	neutralization	NN
cord-313312-h607itv2	137	19	.	.	.
cord-313312-h607itv2	138	1	Taken	take	VBN
cord-313312-h607itv2	138	2	together	together	RB
cord-313312-h607itv2	138	3	,	,	,
cord-313312-h607itv2	138	4	cross	cross	JJ
cord-313312-h607itv2	138	5	-	-	JJ
cord-313312-h607itv2	138	6	reactive	reactive	JJ
cord-313312-h607itv2	138	7	antibodies	antibody	NNS
cord-313312-h607itv2	138	8	that	that	WDT
cord-313312-h607itv2	138	9	can	can	MD
cord-313312-h607itv2	138	10	neutralize	neutralize	VB
cord-313312-h607itv2	138	11	virus	virus	NN
cord-313312-h607itv2	138	12	infection	infection	NN
cord-313312-h607itv2	138	13	are	be	VBP
cord-313312-h607itv2	138	14	likely	likely	RB
cord-313312-h607itv2	138	15	those	those	DT
cord-313312-h607itv2	138	16	that	that	WDT
cord-313312-h607itv2	138	17	can	can	MD
cord-313312-h607itv2	138	18	bind	bind	VB
cord-313312-h607itv2	138	19	to	to	IN
cord-313312-h607itv2	138	20	accessible	accessible	JJ
cord-313312-h607itv2	138	21	epitopes	epitope	NNS
cord-313312-h607itv2	138	22	with	with	IN
cord-313312-h607itv2	138	23	considerable	considerable	JJ
cord-313312-h607itv2	138	24	affinity	affinity	NN
cord-313312-h607itv2	138	25	.	.	.
cord-313312-h607itv2	139	1	Conversely	conversely	RB
cord-313312-h607itv2	139	2	,	,	,
cord-313312-h607itv2	139	3	antibodies	antibody	NNS
cord-313312-h607itv2	139	4	that	that	WDT
cord-313312-h607itv2	139	5	bind	bind	VBP
cord-313312-h607itv2	139	6	weakly	weakly	RB
cord-313312-h607itv2	139	7	and	and	CC
cord-313312-h607itv2	139	8	target	target	VB
cord-313312-h607itv2	139	9	epitopes	epitope	NNS
cord-313312-h607itv2	139	10	with	with	IN
cord-313312-h607itv2	139	11	reduced	reduce	VBN
cord-313312-h607itv2	139	12	accessibility	accessibility	NN
cord-313312-h607itv2	139	13	are	be	VBP
cord-313312-h607itv2	139	14	unlikely	unlikely	JJ
cord-313312-h607itv2	139	15	to	to	TO
cord-313312-h607itv2	139	16	neutralize	neutralize	VB
cord-313312-h607itv2	139	17	viruses	virus	NNS
cord-313312-h607itv2	139	18	,	,	,
cord-313312-h607itv2	139	19	and	and	CC
cord-313312-h607itv2	139	20	may	may	MD
cord-313312-h607itv2	139	21	instead	instead	RB
cord-313312-h607itv2	139	22	enhance	enhance	VB
cord-313312-h607itv2	139	23	viral	viral	JJ
cord-313312-h607itv2	139	24	infection	infection	NN
cord-313312-h607itv2	139	25	via	via	IN
cord-313312-h607itv2	139	26	FcγR	fcγr	RB
cord-313312-h607itv2	139	27	-	-	HYPH
cord-313312-h607itv2	139	28	mediated	mediate	VBN
cord-313312-h607itv2	139	29	uptake	uptake	NN
cord-313312-h607itv2	139	30	.	.	.
cord-313312-h607itv2	140	1	Antibodies	antibody	NNS
cord-313312-h607itv2	140	2	can	can	MD
cord-313312-h607itv2	140	3	neutralize	neutralize	VB
cord-313312-h607itv2	140	4	LAV	LAV	NNP
cord-313312-h607itv2	140	5	strains	strain	NNS
cord-313312-h607itv2	140	6	in	in	IN
cord-313312-h607itv2	140	7	a	a	DT
cord-313312-h607itv2	140	8	variety	variety	NN
cord-313312-h607itv2	140	9	of	of	IN
cord-313312-h607itv2	140	10	ways	way	NNS
cord-313312-h607itv2	140	11	,	,	,
cord-313312-h607itv2	140	12	as	as	IN
cord-313312-h607itv2	140	13	summarized	summarize	VBN
cord-313312-h607itv2	140	14	in	in	IN
cord-313312-h607itv2	140	15	Figure	Figure	NNP
cord-313312-h607itv2	140	16	1	1	CD
cord-313312-h607itv2	140	17	.	.	.
cord-313312-h607itv2	141	1	They	-PRON-	PRP
cord-313312-h607itv2	141	2	may	may	MD
cord-313312-h607itv2	141	3	block	block	VB
cord-313312-h607itv2	141	4	virus	virus	NN
cord-313312-h607itv2	141	5	attachment	attachment	NN
cord-313312-h607itv2	141	6	and	and	CC
cord-313312-h607itv2	141	7	entry	entry	NN
cord-313312-h607itv2	141	8	by	by	IN
cord-313312-h607itv2	141	9	either	either	DT
cord-313312-h607itv2	141	10	binding	bind	VBG
cord-313312-h607itv2	141	11	to	to	IN
cord-313312-h607itv2	141	12	epitopes	epitope	NNS
cord-313312-h607itv2	141	13	that	that	WDT
cord-313312-h607itv2	141	14	are	be	VBP
cord-313312-h607itv2	141	15	directly	directly	RB
cord-313312-h607itv2	141	16	involved	involve	VBN
cord-313312-h607itv2	141	17	in	in	IN
cord-313312-h607itv2	141	18	virus	virus	NN
cord-313312-h607itv2	141	19	-	-	HYPH
cord-313312-h607itv2	141	20	receptor	receptor	NN
cord-313312-h607itv2	141	21	interactions	interaction	NNS
cord-313312-h607itv2	141	22	or	or	CC
cord-313312-h607itv2	141	23	by	by	IN
cord-313312-h607itv2	141	24	imposing	impose	VBG
cord-313312-h607itv2	141	25	steric	steric	JJ
cord-313312-h607itv2	141	26	hindrance	hindrance	NN
cord-313312-h607itv2	141	27	that	that	WDT
cord-313312-h607itv2	141	28	prevent	prevent	VBP
cord-313312-h607itv2	141	29	virus	virus	NN
cord-313312-h607itv2	141	30	interaction	interaction	NN
cord-313312-h607itv2	141	31	with	with	IN
cord-313312-h607itv2	141	32	host	host	NN
cord-313312-h607itv2	141	33	receptors	receptor	NNS
cord-313312-h607itv2	141	34	.	.	.
cord-313312-h607itv2	142	1	As	as	IN
cord-313312-h607itv2	142	2	most	most	JJS
cord-313312-h607itv2	142	3	virus	virus	NN
cord-313312-h607itv2	142	4	structures	structure	NNS
cord-313312-h607itv2	142	5	are	be	VBP
cord-313312-h607itv2	142	6	dynamic	dynamic	JJ
cord-313312-h607itv2	142	7	and	and	CC
cord-313312-h607itv2	142	8	can	can	MD
cord-313312-h607itv2	142	9	change	change	VB
cord-313312-h607itv2	142	10	structural	structural	JJ
cord-313312-h607itv2	142	11	conformations	conformation	NNS
cord-313312-h607itv2	142	12	at	at	IN
cord-313312-h607itv2	142	13	different	different	JJ
cord-313312-h607itv2	142	14	temperatures	temperature	NNS
cord-313312-h607itv2	142	15	,	,	,
cord-313312-h607itv2	142	16	it	-PRON-	PRP
cord-313312-h607itv2	142	17	is	be	VBZ
cord-313312-h607itv2	142	18	thought	think	VBN
cord-313312-h607itv2	142	19	that	that	IN
cord-313312-h607itv2	142	20	antibody	antibody	NN
cord-313312-h607itv2	142	21	binding	bind	VBG
cord-313312-h607itv2	142	22	to	to	IN
cord-313312-h607itv2	142	23	these	these	DT
cord-313312-h607itv2	142	24	dynamic	dynamic	JJ
cord-313312-h607itv2	142	25	structures	structure	NNS
cord-313312-h607itv2	142	26	may	may	MD
cord-313312-h607itv2	142	27	cause	cause	VB
cord-313312-h607itv2	142	28	structural	structural	JJ
cord-313312-h607itv2	142	29	changes	change	NNS
cord-313312-h607itv2	142	30	that	that	WDT
cord-313312-h607itv2	142	31	can	can	MD
cord-313312-h607itv2	142	32	impair	impair	VB
cord-313312-h607itv2	142	33	virus	virus	NN
cord-313312-h607itv2	142	34	attachment	attachment	NN
cord-313312-h607itv2	142	35	,	,	,
cord-313312-h607itv2	142	36	thereby	thereby	RB
cord-313312-h607itv2	142	37	causing	cause	VBG
cord-313312-h607itv2	142	38	virus	virus	NN
cord-313312-h607itv2	142	39	neutralization	neutralization	NN
cord-313312-h607itv2	142	40	[	[	-LRB-
cord-313312-h607itv2	142	41	100	100	CD
cord-313312-h607itv2	142	42	]	]	-RRB-
cord-313312-h607itv2	142	43	.	.	.
cord-313312-h607itv2	143	1	However	however	RB
cord-313312-h607itv2	143	2	,	,	,
cord-313312-h607itv2	143	3	the	the	DT
cord-313312-h607itv2	143	4	blockade	blockade	NN
cord-313312-h607itv2	143	5	of	of	IN
cord-313312-h607itv2	143	6	virus	virus	NN
cord-313312-h607itv2	143	7	-	-	HYPH
cord-313312-h607itv2	143	8	receptor	receptor	NN
cord-313312-h607itv2	143	9	interactions	interaction	NNS
cord-313312-h607itv2	143	10	alone	alone	RB
cord-313312-h607itv2	143	11	may	may	MD
cord-313312-h607itv2	143	12	not	not	RB
cord-313312-h607itv2	143	13	be	be	VB
cord-313312-h607itv2	143	14	able	able	JJ
cord-313312-h607itv2	143	15	to	to	TO
cord-313312-h607itv2	143	16	completely	completely	RB
cord-313312-h607itv2	143	17	neutralize	neutralize	VB
cord-313312-h607itv2	143	18	the	the	DT
cord-313312-h607itv2	143	19	viruses	virus	NNS
cord-313312-h607itv2	143	20	,	,	,
cord-313312-h607itv2	143	21	especially	especially	RB
cord-313312-h607itv2	143	22	in	in	IN
cord-313312-h607itv2	143	23	FcγR	fcγr	NN
cord-313312-h607itv2	143	24	-	-	HYPH
cord-313312-h607itv2	143	25	bearing	bear	VBG
cord-313312-h607itv2	143	26	cells	cell	NNS
cord-313312-h607itv2	143	27	,	,	,
cord-313312-h607itv2	143	28	as	as	IN
cord-313312-h607itv2	143	29	activating	activate	VBG
cord-313312-h607itv2	143	30	FcγRs	FcγRs	NNP
cord-313312-h607itv2	143	31	can	can	MD
cord-313312-h607itv2	143	32	enable	enable	VB
cord-313312-h607itv2	143	33	entry	entry	NN
cord-313312-h607itv2	143	34	of	of	IN
cord-313312-h607itv2	143	35	virus	virus	NN
cord-313312-h607itv2	143	36	-	-	HYPH
cord-313312-h607itv2	143	37	antibody	antibody	NN
cord-313312-h607itv2	143	38	complexes	complex	NNS
cord-313312-h607itv2	143	39	by	by	IN
cord-313312-h607itv2	143	40	FcγR	fcγr	NN
cord-313312-h607itv2	143	41	-	-	HYPH
cord-313312-h607itv2	143	42	mediated	mediate	VBN
cord-313312-h607itv2	143	43	uptake	uptake	NN
cord-313312-h607itv2	143	44	.	.	.
cord-313312-h607itv2	144	1	Thus	thus	RB
cord-313312-h607itv2	144	2	,	,	,
cord-313312-h607itv2	144	3	pre	pre	JJ
cord-313312-h607itv2	144	4	-	-	JJ
cord-313312-h607itv2	144	5	existing	existing	JJ
cord-313312-h607itv2	144	6	antibodies	antibody	NNS
cord-313312-h607itv2	144	7	that	that	WDT
cord-313312-h607itv2	144	8	can	can	MD
cord-313312-h607itv2	144	9	block	block	VB
cord-313312-h607itv2	144	10	viral	viral	JJ
cord-313312-h607itv2	144	11	fusion	fusion	NN
cord-313312-h607itv2	144	12	and	and	CC
cord-313312-h607itv2	144	13	uncoating	uncoating	NN
cord-313312-h607itv2	144	14	will	will	MD
cord-313312-h607itv2	144	15	likely	likely	RB
cord-313312-h607itv2	144	16	be	be	VB
cord-313312-h607itv2	144	17	more	more	RBR
cord-313312-h607itv2	144	18	efficient	efficient	JJ
cord-313312-h607itv2	144	19	in	in	IN
cord-313312-h607itv2	144	20	virus	virus	NN
cord-313312-h607itv2	144	21	neutralization	neutralization	NN
cord-313312-h607itv2	144	22	.	.	.
cord-313312-h607itv2	145	1	In	in	IN
cord-313312-h607itv2	145	2	situations	situation	NNS
cord-313312-h607itv2	145	3	where	where	WRB
cord-313312-h607itv2	145	4	pre	pre	JJ
cord-313312-h607itv2	145	5	-	-	JJ
cord-313312-h607itv2	145	6	existing	existing	JJ
cord-313312-h607itv2	145	7	cross	cross	JJ
cord-313312-h607itv2	145	8	-	-	JJ
cord-313312-h607itv2	145	9	reactive	reactive	JJ
cord-313312-h607itv2	145	10	antibodies	antibody	NNS
cord-313312-h607itv2	145	11	are	be	VBP
cord-313312-h607itv2	145	12	unable	unable	JJ
cord-313312-h607itv2	145	13	to	to	TO
cord-313312-h607itv2	145	14	inhibit	inhibit	VB
cord-313312-h607itv2	145	15	viral	viral	JJ
cord-313312-h607itv2	145	16	fusion	fusion	NN
cord-313312-h607itv2	145	17	processes	process	NNS
cord-313312-h607itv2	145	18	intracellularly	intracellularly	RB
cord-313312-h607itv2	145	19	,	,	,
cord-313312-h607itv2	145	20	high	high	JJ
cord-313312-h607itv2	145	21	concentrations	concentration	NNS
cord-313312-h607itv2	145	22	of	of	IN
cord-313312-h607itv2	145	23	antibodies	antibody	NNS
cord-313312-h607itv2	145	24	may	may	MD
cord-313312-h607itv2	145	25	enable	enable	VB
cord-313312-h607itv2	145	26	the	the	DT
cord-313312-h607itv2	145	27	formation	formation	NN
cord-313312-h607itv2	145	28	of	of	IN
cord-313312-h607itv2	145	29	viral	viral	JJ
cord-313312-h607itv2	145	30	immune	immune	JJ
cord-313312-h607itv2	145	31	aggregates	aggregate	NNS
cord-313312-h607itv2	145	32	that	that	WDT
cord-313312-h607itv2	145	33	influence	influence	VBP
cord-313312-h607itv2	145	34	the	the	DT
cord-313312-h607itv2	145	35	types	type	NNS
cord-313312-h607itv2	145	36	of	of	IN
cord-313312-h607itv2	145	37	FcγRs	FcγRs	NNP
cord-313312-h607itv2	145	38	engaged	engage	VBD
cord-313312-h607itv2	145	39	.	.	.
cord-313312-h607itv2	146	1	These	these	DT
cord-313312-h607itv2	146	2	large	large	JJ
cord-313312-h607itv2	146	3	viral	viral	JJ
cord-313312-h607itv2	146	4	aggregates	aggregate	NNS
cord-313312-h607itv2	146	5	can	can	MD
cord-313312-h607itv2	146	6	then	then	RB
cord-313312-h607itv2	146	7	inhibit	inhibit	VB
cord-313312-h607itv2	146	8	phagocytosis	phagocytosis	NN
cord-313312-h607itv2	146	9	by	by	IN
cord-313312-h607itv2	146	10	co	co	NN
cord-313312-h607itv2	146	11	-	-	JJ
cord-313312-h607itv2	146	12	ligating	ligate	VBG
cord-313312-h607itv2	146	13	the	the	DT
cord-313312-h607itv2	146	14	lowly	lowly	JJ
cord-313312-h607itv2	146	15	expressed	express	VBN
cord-313312-h607itv2	146	16	inhibitory	inhibitory	JJ
cord-313312-h607itv2	146	17	receptor	receptor	NN
cord-313312-h607itv2	146	18	FcγRIIB	fcγriib	NN
cord-313312-h607itv2	146	19	that	that	WDT
cord-313312-h607itv2	146	20	inhibit	inhibit	VBP
cord-313312-h607itv2	146	21	phagocytosis	phagocytosis	NN
cord-313312-h607itv2	146	22	[	[	-LRB-
cord-313312-h607itv2	146	23	101	101	CD
cord-313312-h607itv2	146	24	,	,	,
cord-313312-h607itv2	146	25	102	102	CD
cord-313312-h607itv2	146	26	]	]	-RRB-
cord-313312-h607itv2	146	27	.	.	.
cord-313312-h607itv2	147	1	Finally	finally	RB
cord-313312-h607itv2	147	2	,	,	,
cord-313312-h607itv2	147	3	there	there	EX
cord-313312-h607itv2	147	4	have	have	VBP
cord-313312-h607itv2	147	5	been	be	VBN
cord-313312-h607itv2	147	6	theories	theory	NNS
cord-313312-h607itv2	147	7	suggesting	suggest	VBG
cord-313312-h607itv2	147	8	that	that	IN
cord-313312-h607itv2	147	9	FcγR	fcγr	JJ
cord-313312-h607itv2	147	10	cross	cross	NN
cord-313312-h607itv2	147	11	-	-	NN
cord-313312-h607itv2	147	12	linking	link	VBG
cord-313312-h607itv2	147	13	by	by	IN
cord-313312-h607itv2	147	14	virus	virus	NN
cord-313312-h607itv2	147	15	immune	immune	JJ
cord-313312-h607itv2	147	16	complexes	complex	NNS
cord-313312-h607itv2	147	17	may	may	MD
cord-313312-h607itv2	147	18	increase	increase	VB
cord-313312-h607itv2	147	19	the	the	DT
cord-313312-h607itv2	147	20	production	production	NN
cord-313312-h607itv2	147	21	of	of	IN
cord-313312-h607itv2	147	22	IL-10	IL-10	NNP
cord-313312-h607itv2	147	23	that	that	WDT
cord-313312-h607itv2	147	24	abolishes	abolish	VBZ
cord-313312-h607itv2	147	25	innate	innate	JJ
cord-313312-h607itv2	147	26	immune	immune	JJ
cord-313312-h607itv2	147	27	responses	response	NNS
cord-313312-h607itv2	147	28	[	[	-LRB-
cord-313312-h607itv2	147	29	103	103	CD
cord-313312-h607itv2	147	30	]	]	-RRB-
cord-313312-h607itv2	147	31	.	.	.
cord-313312-h607itv2	148	1	However	however	RB
cord-313312-h607itv2	148	2	,	,	,
cord-313312-h607itv2	148	3	more	more	JJR
cord-313312-h607itv2	148	4	experimental	experimental	JJ
cord-313312-h607itv2	148	5	evidence	evidence	NN
cord-313312-h607itv2	148	6	will	will	MD
cord-313312-h607itv2	148	7	be	be	VB
cord-313312-h607itv2	148	8	required	require	VBN
cord-313312-h607itv2	148	9	to	to	TO
cord-313312-h607itv2	148	10	support	support	VB
cord-313312-h607itv2	148	11	this	this	DT
cord-313312-h607itv2	148	12	theory	theory	NN
cord-313312-h607itv2	148	13	.	.	.
cord-313312-h607itv2	149	1	Viruses	virus	NNS
cord-313312-h607itv2	149	2	2020	2020	CD
cord-313312-h607itv2	149	3	,	,	,
cord-313312-h607itv2	149	4	12	12	CD
cord-313312-h607itv2	149	5	,	,	,
cord-313312-h607itv2	149	6	x	x	NN
cord-313312-h607itv2	149	7	FOR	for	IN
cord-313312-h607itv2	149	8	PEER	PEER	NNP
cord-313312-h607itv2	149	9	REVIEW	REVIEW	NNP
cord-313312-h607itv2	149	10	7	7	CD
cord-313312-h607itv2	149	11	of	of	IN
cord-313312-h607itv2	149	12	17	17	CD
cord-313312-h607itv2	149	13	virus	virus	NN
cord-313312-h607itv2	149	14	maturation	maturation	NN
cord-313312-h607itv2	149	15	states	state	NNS
cord-313312-h607itv2	149	16	[	[	-LRB-
cord-313312-h607itv2	149	17	99	99	CD
cord-313312-h607itv2	149	18	]	]	-RRB-
cord-313312-h607itv2	149	19	.	.	.
cord-313312-h607itv2	150	1	The	the	DT
cord-313312-h607itv2	150	2	epitope	epitope	NN
cord-313312-h607itv2	150	3	availability	availability	NN
cord-313312-h607itv2	150	4	would	would	MD
cord-313312-h607itv2	150	5	thus	thus	RB
cord-313312-h607itv2	150	6	affect	affect	VB
cord-313312-h607itv2	150	7	the	the	DT
cord-313312-h607itv2	150	8	fraction	fraction	NN
cord-313312-h607itv2	150	9	of	of	IN
cord-313312-h607itv2	150	10	epitope	epitope	NN
cord-313312-h607itv2	150	11	occupancy	occupancy	NN
cord-313312-h607itv2	150	12	that	that	WDT
cord-313312-h607itv2	150	13	will	will	MD
cord-313312-h607itv2	150	14	be	be	VB
cord-313312-h607itv2	150	15	required	require	VBN
cord-313312-h607itv2	150	16	for	for	IN
cord-313312-h607itv2	150	17	virus	virus	NN
cord-313312-h607itv2	150	18	neutralization	neutralization	NN
cord-313312-h607itv2	150	19	.	.	.
cord-313312-h607itv2	151	1	Taken	take	VBN
cord-313312-h607itv2	151	2	together	together	RB
cord-313312-h607itv2	151	3	,	,	,
cord-313312-h607itv2	151	4	cross	cross	JJ
cord-313312-h607itv2	151	5	-	-	JJ
cord-313312-h607itv2	151	6	reactive	reactive	JJ
cord-313312-h607itv2	151	7	antibodies	antibody	NNS
cord-313312-h607itv2	151	8	that	that	WDT
cord-313312-h607itv2	151	9	can	can	MD
cord-313312-h607itv2	151	10	neutralize	neutralize	VB
cord-313312-h607itv2	151	11	virus	virus	NN
cord-313312-h607itv2	151	12	infection	infection	NN
cord-313312-h607itv2	151	13	are	be	VBP
cord-313312-h607itv2	151	14	likely	likely	RB
cord-313312-h607itv2	151	15	those	those	DT
cord-313312-h607itv2	151	16	that	that	WDT
cord-313312-h607itv2	151	17	can	can	MD
cord-313312-h607itv2	151	18	bind	bind	VB
cord-313312-h607itv2	151	19	to	to	IN
cord-313312-h607itv2	151	20	accessible	accessible	JJ
cord-313312-h607itv2	151	21	epitopes	epitope	NNS
cord-313312-h607itv2	151	22	with	with	IN
cord-313312-h607itv2	151	23	considerable	considerable	JJ
cord-313312-h607itv2	151	24	affinity	affinity	NN
cord-313312-h607itv2	151	25	.	.	.
cord-313312-h607itv2	152	1	Conversely	conversely	RB
cord-313312-h607itv2	152	2	,	,	,
cord-313312-h607itv2	152	3	antibodies	antibody	NNS
cord-313312-h607itv2	152	4	that	that	WDT
cord-313312-h607itv2	152	5	bind	bind	VBP
cord-313312-h607itv2	152	6	weakly	weakly	RB
cord-313312-h607itv2	152	7	and	and	CC
cord-313312-h607itv2	152	8	target	target	VB
cord-313312-h607itv2	152	9	epitopes	epitope	NNS
cord-313312-h607itv2	152	10	with	with	IN
cord-313312-h607itv2	152	11	reduced	reduce	VBN
cord-313312-h607itv2	152	12	accessibility	accessibility	NN
cord-313312-h607itv2	152	13	are	be	VBP
cord-313312-h607itv2	152	14	unlikely	unlikely	JJ
cord-313312-h607itv2	152	15	to	to	TO
cord-313312-h607itv2	152	16	neutralize	neutralize	VB
cord-313312-h607itv2	152	17	viruses	virus	NNS
cord-313312-h607itv2	152	18	,	,	,
cord-313312-h607itv2	152	19	and	and	CC
cord-313312-h607itv2	152	20	may	may	MD
cord-313312-h607itv2	152	21	instead	instead	RB
cord-313312-h607itv2	152	22	enhance	enhance	VB
cord-313312-h607itv2	152	23	viral	viral	JJ
cord-313312-h607itv2	152	24	infection	infection	NN
cord-313312-h607itv2	152	25	via	via	IN
cord-313312-h607itv2	152	26	FcγRmediated	fcγrmediated	JJ
cord-313312-h607itv2	152	27	uptake	uptake	NN
cord-313312-h607itv2	152	28	.	.	.
cord-313312-h607itv2	153	1	Antibodies	antibody	NNS
cord-313312-h607itv2	153	2	can	can	MD
cord-313312-h607itv2	153	3	neutralize	neutralize	VB
cord-313312-h607itv2	153	4	LAV	LAV	NNP
cord-313312-h607itv2	153	5	strains	strain	NNS
cord-313312-h607itv2	153	6	in	in	IN
cord-313312-h607itv2	153	7	a	a	DT
cord-313312-h607itv2	153	8	variety	variety	NN
cord-313312-h607itv2	153	9	of	of	IN
cord-313312-h607itv2	153	10	ways	way	NNS
cord-313312-h607itv2	153	11	,	,	,
cord-313312-h607itv2	153	12	as	as	IN
cord-313312-h607itv2	153	13	summarized	summarize	VBN
cord-313312-h607itv2	153	14	in	in	IN
cord-313312-h607itv2	153	15	Figure	Figure	NNP
cord-313312-h607itv2	153	16	1	1	CD
cord-313312-h607itv2	153	17	.	.	.
cord-313312-h607itv2	154	1	They	-PRON-	PRP
cord-313312-h607itv2	154	2	may	may	MD
cord-313312-h607itv2	154	3	block	block	VB
cord-313312-h607itv2	154	4	virus	virus	NN
cord-313312-h607itv2	154	5	attachment	attachment	NN
cord-313312-h607itv2	154	6	and	and	CC
cord-313312-h607itv2	154	7	entry	entry	NN
cord-313312-h607itv2	154	8	by	by	IN
cord-313312-h607itv2	154	9	either	either	DT
cord-313312-h607itv2	154	10	binding	bind	VBG
cord-313312-h607itv2	154	11	to	to	IN
cord-313312-h607itv2	154	12	epitopes	epitope	NNS
cord-313312-h607itv2	154	13	that	that	WDT
cord-313312-h607itv2	154	14	are	be	VBP
cord-313312-h607itv2	154	15	directly	directly	RB
cord-313312-h607itv2	154	16	involved	involve	VBN
cord-313312-h607itv2	154	17	in	in	IN
cord-313312-h607itv2	154	18	virus	virus	NN
cord-313312-h607itv2	154	19	-	-	HYPH
cord-313312-h607itv2	154	20	receptor	receptor	NN
cord-313312-h607itv2	154	21	interactions	interaction	NNS
cord-313312-h607itv2	154	22	or	or	CC
cord-313312-h607itv2	154	23	by	by	IN
cord-313312-h607itv2	154	24	imposing	impose	VBG
cord-313312-h607itv2	154	25	steric	steric	JJ
cord-313312-h607itv2	154	26	hindrance	hindrance	NN
cord-313312-h607itv2	154	27	that	that	WDT
cord-313312-h607itv2	154	28	prevent	prevent	VBP
cord-313312-h607itv2	154	29	virus	virus	NN
cord-313312-h607itv2	154	30	interaction	interaction	NN
cord-313312-h607itv2	154	31	with	with	IN
cord-313312-h607itv2	154	32	host	host	NN
cord-313312-h607itv2	154	33	receptors	receptor	NNS
cord-313312-h607itv2	154	34	.	.	.
cord-313312-h607itv2	155	1	As	as	IN
cord-313312-h607itv2	155	2	most	most	JJS
cord-313312-h607itv2	155	3	virus	virus	NN
cord-313312-h607itv2	155	4	structures	structure	NNS
cord-313312-h607itv2	155	5	are	be	VBP
cord-313312-h607itv2	155	6	dynamic	dynamic	JJ
cord-313312-h607itv2	155	7	and	and	CC
cord-313312-h607itv2	155	8	can	can	MD
cord-313312-h607itv2	155	9	change	change	VB
cord-313312-h607itv2	155	10	structural	structural	JJ
cord-313312-h607itv2	155	11	conformations	conformation	NNS
cord-313312-h607itv2	155	12	at	at	IN
cord-313312-h607itv2	155	13	different	different	JJ
cord-313312-h607itv2	155	14	temperatures	temperature	NNS
cord-313312-h607itv2	155	15	,	,	,
cord-313312-h607itv2	155	16	it	-PRON-	PRP
cord-313312-h607itv2	155	17	is	be	VBZ
cord-313312-h607itv2	155	18	thought	think	VBN
cord-313312-h607itv2	155	19	that	that	IN
cord-313312-h607itv2	155	20	antibody	antibody	NN
cord-313312-h607itv2	155	21	binding	bind	VBG
cord-313312-h607itv2	155	22	to	to	IN
cord-313312-h607itv2	155	23	these	these	DT
cord-313312-h607itv2	155	24	dynamic	dynamic	JJ
cord-313312-h607itv2	155	25	structures	structure	NNS
cord-313312-h607itv2	155	26	may	may	MD
cord-313312-h607itv2	155	27	cause	cause	VB
cord-313312-h607itv2	155	28	structural	structural	JJ
cord-313312-h607itv2	155	29	changes	change	NNS
cord-313312-h607itv2	155	30	that	that	WDT
cord-313312-h607itv2	155	31	can	can	MD
cord-313312-h607itv2	155	32	impair	impair	VB
cord-313312-h607itv2	155	33	virus	virus	NN
cord-313312-h607itv2	155	34	attachment	attachment	NN
cord-313312-h607itv2	155	35	,	,	,
cord-313312-h607itv2	155	36	thereby	thereby	RB
cord-313312-h607itv2	155	37	causing	cause	VBG
cord-313312-h607itv2	155	38	virus	virus	NN
cord-313312-h607itv2	155	39	neutralization	neutralization	NN
cord-313312-h607itv2	155	40	[	[	-LRB-
cord-313312-h607itv2	155	41	100	100	CD
cord-313312-h607itv2	155	42	]	]	-RRB-
cord-313312-h607itv2	155	43	.	.	.
cord-313312-h607itv2	156	1	However	however	RB
cord-313312-h607itv2	156	2	,	,	,
cord-313312-h607itv2	156	3	the	the	DT
cord-313312-h607itv2	156	4	blockade	blockade	NN
cord-313312-h607itv2	156	5	of	of	IN
cord-313312-h607itv2	156	6	virus	virus	NN
cord-313312-h607itv2	156	7	-	-	HYPH
cord-313312-h607itv2	156	8	receptor	receptor	NN
cord-313312-h607itv2	156	9	interactions	interaction	NNS
cord-313312-h607itv2	156	10	alone	alone	RB
cord-313312-h607itv2	156	11	may	may	MD
cord-313312-h607itv2	156	12	not	not	RB
cord-313312-h607itv2	156	13	be	be	VB
cord-313312-h607itv2	156	14	able	able	JJ
cord-313312-h607itv2	156	15	to	to	TO
cord-313312-h607itv2	156	16	completely	completely	RB
cord-313312-h607itv2	156	17	neutralize	neutralize	VB
cord-313312-h607itv2	156	18	the	the	DT
cord-313312-h607itv2	156	19	viruses	virus	NNS
cord-313312-h607itv2	156	20	,	,	,
cord-313312-h607itv2	156	21	especially	especially	RB
cord-313312-h607itv2	156	22	in	in	IN
cord-313312-h607itv2	156	23	FcγR	fcγr	NN
cord-313312-h607itv2	156	24	-	-	HYPH
cord-313312-h607itv2	156	25	bearing	bear	VBG
cord-313312-h607itv2	156	26	cells	cell	NNS
cord-313312-h607itv2	156	27	,	,	,
cord-313312-h607itv2	156	28	as	as	IN
cord-313312-h607itv2	156	29	activating	activate	VBG
cord-313312-h607itv2	156	30	FcγRs	FcγRs	NNP
cord-313312-h607itv2	156	31	can	can	MD
cord-313312-h607itv2	156	32	enable	enable	VB
cord-313312-h607itv2	156	33	entry	entry	NN
cord-313312-h607itv2	156	34	of	of	IN
cord-313312-h607itv2	156	35	virus	virus	NN
cord-313312-h607itv2	156	36	-	-	HYPH
cord-313312-h607itv2	156	37	antibody	antibody	NN
cord-313312-h607itv2	156	38	complexes	complex	NNS
cord-313312-h607itv2	156	39	by	by	IN
cord-313312-h607itv2	156	40	FcγR	fcγr	NN
cord-313312-h607itv2	156	41	-	-	HYPH
cord-313312-h607itv2	156	42	mediated	mediate	VBN
cord-313312-h607itv2	156	43	uptake	uptake	NN
cord-313312-h607itv2	156	44	.	.	.
cord-313312-h607itv2	157	1	Thus	thus	RB
cord-313312-h607itv2	157	2	,	,	,
cord-313312-h607itv2	157	3	pre	pre	JJ
cord-313312-h607itv2	157	4	-	-	JJ
cord-313312-h607itv2	157	5	existing	existing	JJ
cord-313312-h607itv2	157	6	antibodies	antibody	NNS
cord-313312-h607itv2	157	7	that	that	WDT
cord-313312-h607itv2	157	8	can	can	MD
cord-313312-h607itv2	157	9	block	block	VB
cord-313312-h607itv2	157	10	viral	viral	JJ
cord-313312-h607itv2	157	11	fusion	fusion	NN
cord-313312-h607itv2	157	12	and	and	CC
cord-313312-h607itv2	157	13	uncoating	uncoating	NN
cord-313312-h607itv2	157	14	will	will	MD
cord-313312-h607itv2	157	15	likely	likely	RB
cord-313312-h607itv2	157	16	be	be	VB
cord-313312-h607itv2	157	17	more	more	RBR
cord-313312-h607itv2	157	18	efficient	efficient	JJ
cord-313312-h607itv2	157	19	in	in	IN
cord-313312-h607itv2	157	20	virus	virus	NN
cord-313312-h607itv2	157	21	neutralization	neutralization	NN
cord-313312-h607itv2	157	22	.	.	.
cord-313312-h607itv2	158	1	In	in	IN
cord-313312-h607itv2	158	2	situations	situation	NNS
cord-313312-h607itv2	158	3	where	where	WRB
cord-313312-h607itv2	158	4	pre	pre	JJ
cord-313312-h607itv2	158	5	-	-	JJ
cord-313312-h607itv2	158	6	existing	existing	JJ
cord-313312-h607itv2	158	7	cross	cross	JJ
cord-313312-h607itv2	158	8	-	-	JJ
cord-313312-h607itv2	158	9	reactive	reactive	JJ
cord-313312-h607itv2	158	10	antibodies	antibody	NNS
cord-313312-h607itv2	158	11	are	be	VBP
cord-313312-h607itv2	158	12	unable	unable	JJ
cord-313312-h607itv2	158	13	to	to	TO
cord-313312-h607itv2	158	14	inhibit	inhibit	VB
cord-313312-h607itv2	158	15	viral	viral	JJ
cord-313312-h607itv2	158	16	fusion	fusion	NN
cord-313312-h607itv2	158	17	processes	process	NNS
cord-313312-h607itv2	158	18	intracellularly	intracellularly	RB
cord-313312-h607itv2	158	19	,	,	,
cord-313312-h607itv2	158	20	high	high	JJ
cord-313312-h607itv2	158	21	concentrations	concentration	NNS
cord-313312-h607itv2	158	22	of	of	IN
cord-313312-h607itv2	158	23	antibodies	antibody	NNS
cord-313312-h607itv2	158	24	may	may	MD
cord-313312-h607itv2	158	25	enable	enable	VB
cord-313312-h607itv2	158	26	the	the	DT
cord-313312-h607itv2	158	27	formation	formation	NN
cord-313312-h607itv2	158	28	of	of	IN
cord-313312-h607itv2	158	29	viral	viral	JJ
cord-313312-h607itv2	158	30	immune	immune	JJ
cord-313312-h607itv2	158	31	aggregates	aggregate	NNS
cord-313312-h607itv2	158	32	that	that	WDT
cord-313312-h607itv2	158	33	influence	influence	VBP
cord-313312-h607itv2	158	34	the	the	DT
cord-313312-h607itv2	158	35	types	type	NNS
cord-313312-h607itv2	158	36	of	of	IN
cord-313312-h607itv2	158	37	FcγRs	FcγRs	NNP
cord-313312-h607itv2	158	38	engaged	engage	VBD
cord-313312-h607itv2	158	39	.	.	.
cord-313312-h607itv2	159	1	These	these	DT
cord-313312-h607itv2	159	2	large	large	JJ
cord-313312-h607itv2	159	3	viral	viral	JJ
cord-313312-h607itv2	159	4	aggregates	aggregate	NNS
cord-313312-h607itv2	159	5	can	can	MD
cord-313312-h607itv2	159	6	then	then	RB
cord-313312-h607itv2	159	7	inhibit	inhibit	VB
cord-313312-h607itv2	159	8	phagocytosis	phagocytosis	NN
cord-313312-h607itv2	159	9	by	by	IN
cord-313312-h607itv2	159	10	co	co	NN
cord-313312-h607itv2	159	11	-	-	JJ
cord-313312-h607itv2	159	12	ligating	ligate	VBG
cord-313312-h607itv2	159	13	the	the	DT
cord-313312-h607itv2	159	14	lowly	lowly	JJ
cord-313312-h607itv2	159	15	expressed	express	VBN
cord-313312-h607itv2	159	16	inhibitory	inhibitory	JJ
cord-313312-h607itv2	159	17	receptor	receptor	NN
cord-313312-h607itv2	159	18	FcγRIIB	fcγriib	NN
cord-313312-h607itv2	159	19	that	that	WDT
cord-313312-h607itv2	159	20	inhibit	inhibit	VBP
cord-313312-h607itv2	159	21	phagocytosis	phagocytosis	NN
cord-313312-h607itv2	159	22	[	[	-LRB-
cord-313312-h607itv2	159	23	101	101	CD
cord-313312-h607itv2	159	24	,	,	,
cord-313312-h607itv2	159	25	102	102	CD
cord-313312-h607itv2	159	26	]	]	-RRB-
cord-313312-h607itv2	159	27	.	.	.
cord-313312-h607itv2	160	1	Finally	finally	RB
cord-313312-h607itv2	160	2	,	,	,
cord-313312-h607itv2	160	3	there	there	EX
cord-313312-h607itv2	160	4	have	have	VBP
cord-313312-h607itv2	160	5	been	be	VBN
cord-313312-h607itv2	160	6	theories	theory	NNS
cord-313312-h607itv2	160	7	suggesting	suggest	VBG
cord-313312-h607itv2	160	8	that	that	IN
cord-313312-h607itv2	160	9	FcγR	fcγr	JJ
cord-313312-h607itv2	160	10	cross	cross	NN
cord-313312-h607itv2	160	11	-	-	NN
cord-313312-h607itv2	160	12	linking	link	VBG
cord-313312-h607itv2	160	13	by	by	IN
cord-313312-h607itv2	160	14	virus	virus	NN
cord-313312-h607itv2	160	15	immune	immune	JJ
cord-313312-h607itv2	160	16	complexes	complex	NNS
cord-313312-h607itv2	160	17	may	may	MD
cord-313312-h607itv2	160	18	increase	increase	VB
cord-313312-h607itv2	160	19	the	the	DT
cord-313312-h607itv2	160	20	production	production	NN
cord-313312-h607itv2	160	21	of	of	IN
cord-313312-h607itv2	160	22	IL-10	IL-10	NNP
cord-313312-h607itv2	160	23	that	that	WDT
cord-313312-h607itv2	160	24	abolishes	abolish	VBZ
cord-313312-h607itv2	160	25	innate	innate	JJ
cord-313312-h607itv2	160	26	immune	immune	JJ
cord-313312-h607itv2	160	27	responses	response	NNS
cord-313312-h607itv2	160	28	[	[	-LRB-
cord-313312-h607itv2	160	29	103	103	CD
cord-313312-h607itv2	160	30	]	]	-RRB-
cord-313312-h607itv2	160	31	.	.	.
cord-313312-h607itv2	161	1	However	however	RB
cord-313312-h607itv2	161	2	,	,	,
cord-313312-h607itv2	161	3	more	more	JJR
cord-313312-h607itv2	161	4	experimental	experimental	JJ
cord-313312-h607itv2	161	5	evidence	evidence	NN
cord-313312-h607itv2	161	6	will	will	MD
cord-313312-h607itv2	161	7	be	be	VB
cord-313312-h607itv2	161	8	required	require	VBN
cord-313312-h607itv2	161	9	to	to	TO
cord-313312-h607itv2	161	10	support	support	VB
cord-313312-h607itv2	161	11	this	this	DT
cord-313312-h607itv2	161	12	theory	theory	NN
cord-313312-h607itv2	161	13	.	.	.
cord-313312-h607itv2	161	14	 	 	_SP
cord-313312-h607itv2	162	1	Unlike	unlike	IN
cord-313312-h607itv2	162	2	myeloid	myeloid	NN
cord-313312-h607itv2	162	3	cells	cell	NNS
cord-313312-h607itv2	162	4	,	,	,
cord-313312-h607itv2	162	5	B	b	NN
cord-313312-h607itv2	162	6	-	-	HYPH
cord-313312-h607itv2	162	7	cells	cell	NNS
cord-313312-h607itv2	162	8	exclusively	exclusively	RB
cord-313312-h607itv2	162	9	express	express	VBP
cord-313312-h607itv2	162	10	FcγRIIB	fcγriib	NN
cord-313312-h607itv2	162	11	but	but	CC
cord-313312-h607itv2	162	12	not	not	RB
cord-313312-h607itv2	162	13	the	the	DT
cord-313312-h607itv2	162	14	activating	activate	VBG
cord-313312-h607itv2	162	15	FcγRs	FcγRs	NNP
cord-313312-h607itv2	162	16	[	[	-LRB-
cord-313312-h607itv2	162	17	86	86	CD
cord-313312-h607itv2	162	18	]	]	-RRB-
cord-313312-h607itv2	162	19	.	.	.
cord-313312-h607itv2	163	1	Therefore	therefore	RB
cord-313312-h607itv2	163	2	,	,	,
cord-313312-h607itv2	163	3	cross	cross	NN
cord-313312-h607itv2	163	4	-	-	NN
cord-313312-h607itv2	163	5	linking	linking	NN
cord-313312-h607itv2	163	6	of	of	IN
cord-313312-h607itv2	163	7	the	the	DT
cord-313312-h607itv2	163	8	B	b	NN
cord-313312-h607itv2	163	9	-	-	HYPH
cord-313312-h607itv2	163	10	cell	cell	NN
cord-313312-h607itv2	163	11	receptor	receptor	NN
cord-313312-h607itv2	163	12	(	(	-LRB-
cord-313312-h607itv2	163	13	BCR	BCR	NNP
cord-313312-h607itv2	163	14	)	)	-RRB-
cord-313312-h607itv2	163	15	with	with	IN
cord-313312-h607itv2	163	16	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	163	17	mediated	mediate	VBN
cord-313312-h607itv2	163	18	by	by	IN
cord-313312-h607itv2	163	19	virus	virus	NN
cord-313312-h607itv2	163	20	immune	immune	JJ
cord-313312-h607itv2	163	21	complexes	complex	NNS
cord-313312-h607itv2	163	22	can	can	MD
cord-313312-h607itv2	163	23	lead	lead	VB
cord-313312-h607itv2	163	24	to	to	IN
cord-313312-h607itv2	163	25	the	the	DT
cord-313312-h607itv2	163	26	inhibition	inhibition	NN
cord-313312-h607itv2	163	27	of	of	IN
cord-313312-h607itv2	163	28	B	b	NN
cord-313312-h607itv2	163	29	-	-	HYPH
cord-313312-h607itv2	163	30	cell	cell	NN
cord-313312-h607itv2	163	31	activation	activation	NN
cord-313312-h607itv2	163	32	(	(	-LRB-
cord-313312-h607itv2	163	33	Figure	figure	NN
cord-313312-h607itv2	163	34	2a	2a	CD
cord-313312-h607itv2	163	35	)	)	-RRB-
cord-313312-h607itv2	163	36	.	.	.
cord-313312-h607itv2	164	1	Indeed	indeed	RB
cord-313312-h607itv2	164	2	,	,	,
cord-313312-h607itv2	164	3	by	by	IN
cord-313312-h607itv2	164	4	adding	add	VBG
cord-313312-h607itv2	164	5	sheep	sheep	NNS
cord-313312-h607itv2	164	6	red	red	JJ
cord-313312-h607itv2	164	7	blood	blood	NN
cord-313312-h607itv2	164	8	cell	cell	NN
cord-313312-h607itv2	164	9	-	-	HYPH
cord-313312-h607itv2	164	10	specific	specific	JJ
cord-313312-h607itv2	164	11	(	(	-LRB-
cord-313312-h607itv2	164	12	SBRC	SBRC	NNP
cord-313312-h607itv2	164	13	)	)	-RRB-
cord-313312-h607itv2	164	14	IgG	IgG	NNP
cord-313312-h607itv2	164	15	to	to	TO
cord-313312-h607itv2	164	16	SRBCs	SRBCs	NNP
cord-313312-h607itv2	164	17	,	,	,
cord-313312-h607itv2	164	18	B	b	NN
cord-313312-h607itv2	164	19	-	-	HYPH
cord-313312-h607itv2	164	20	cell	cell	NN
cord-313312-h607itv2	164	21	antibody	antibody	NN
cord-313312-h607itv2	164	22	secretion	secretion	NN
cord-313312-h607itv2	164	23	is	be	VBZ
cord-313312-h607itv2	164	24	reduced	reduce	VBN
cord-313312-h607itv2	164	25	[	[	-LRB-
cord-313312-h607itv2	164	26	104	104	CD
cord-313312-h607itv2	164	27	]	]	-RRB-
cord-313312-h607itv2	164	28	.	.	.
cord-313312-h607itv2	165	1	Similarly	similarly	RB
cord-313312-h607itv2	165	2	,	,	,
cord-313312-h607itv2	165	3	using	use	VBG
cord-313312-h607itv2	165	4	the	the	DT
cord-313312-h607itv2	165	5	cotton	cotton	NN
cord-313312-h607itv2	165	6	rat	rat	NN
cord-313312-h607itv2	165	7	model	model	NN
cord-313312-h607itv2	165	8	of	of	IN
cord-313312-h607itv2	165	9	MV	MV	NNP
cord-313312-h607itv2	165	10	vaccination	vaccination	NN
cord-313312-h607itv2	165	11	,	,	,
cord-313312-h607itv2	165	12	maternal	maternal	JJ
cord-313312-h607itv2	165	13	antibodies	antibody	NNS
cord-313312-h607itv2	165	14	were	be	VBD
cord-313312-h607itv2	165	15	demonstrated	demonstrate	VBN
cord-313312-h607itv2	165	16	to	to	TO
cord-313312-h607itv2	165	17	inhibit	inhibit	VB
cord-313312-h607itv2	165	18	B	b	NN
cord-313312-h607itv2	165	19	-	-	HYPH
cord-313312-h607itv2	165	20	cells	cell	NNS
cord-313312-h607itv2	165	21	by	by	IN
cord-313312-h607itv2	165	22	the	the	DT
cord-313312-h607itv2	165	23	cross	cross	NN
cord-313312-h607itv2	165	24	-	-	JJ
cord-313312-h607itv2	165	25	linking	linking	NN
cord-313312-h607itv2	165	26	of	of	IN
cord-313312-h607itv2	165	27	BCR	BCR	NNP
cord-313312-h607itv2	165	28	and	and	CC
cord-313312-h607itv2	165	29	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	165	30	[	[	-LRB-
cord-313312-h607itv2	165	31	105	105	CD
cord-313312-h607itv2	165	32	]	]	-RRB-
cord-313312-h607itv2	165	33	.	.	.
cord-313312-h607itv2	166	1	However	however	RB
cord-313312-h607itv2	166	2	,	,	,
cord-313312-h607itv2	166	3	this	this	DT
cord-313312-h607itv2	166	4	mechanism	mechanism	NN
cord-313312-h607itv2	166	5	of	of	IN
cord-313312-h607itv2	166	6	inhibition	inhibition	NN
cord-313312-h607itv2	166	7	has	have	VBZ
cord-313312-h607itv2	166	8	not	not	RB
cord-313312-h607itv2	166	9	been	be	VBN
cord-313312-h607itv2	166	10	demonstrated	demonstrate	VBN
cord-313312-h607itv2	166	11	for	for	IN
cord-313312-h607itv2	166	12	other	other	JJ
cord-313312-h607itv2	166	13	viruses	virus	NNS
cord-313312-h607itv2	166	14	.	.	.
cord-313312-h607itv2	167	1	It	-PRON-	PRP
cord-313312-h607itv2	167	2	is	be	VBZ
cord-313312-h607itv2	167	3	conceivable	conceivable	JJ
cord-313312-h607itv2	167	4	that	that	IN
cord-313312-h607itv2	167	5	this	this	DT
cord-313312-h607itv2	167	6	mode	mode	NN
cord-313312-h607itv2	167	7	of	of	IN
cord-313312-h607itv2	167	8	inhibition	inhibition	NN
cord-313312-h607itv2	167	9	is	be	VBZ
cord-313312-h607itv2	167	10	dependent	dependent	JJ
cord-313312-h607itv2	167	11	on	on	IN
cord-313312-h607itv2	167	12	the	the	DT
cord-313312-h607itv2	167	13	size	size	NN
cord-313312-h607itv2	167	14	of	of	IN
cord-313312-h607itv2	167	15	the	the	DT
cord-313312-h607itv2	167	16	virus	virus	NN
cord-313312-h607itv2	167	17	-	-	HYPH
cord-313312-h607itv2	167	18	antibody	antibody	NN
cord-313312-h607itv2	167	19	immune	immune	JJ
cord-313312-h607itv2	167	20	complexes	complex	NNS
cord-313312-h607itv2	167	21	,	,	,
cord-313312-h607itv2	167	22	as	as	IN
cord-313312-h607itv2	167	23	immunization	immunization	NN
cord-313312-h607itv2	167	24	of	of	IN
cord-313312-h607itv2	167	25	small	small	JJ
cord-313312-h607itv2	167	26	polypeptides	polypeptide	NNS
cord-313312-h607itv2	167	27	can	can	MD
cord-313312-h607itv2	167	28	escape	escape	VB
cord-313312-h607itv2	167	29	maternal	maternal	JJ
cord-313312-h607itv2	167	30	antibody	antibody	NN
cord-313312-h607itv2	167	31	inhibition	inhibition	NN
cord-313312-h607itv2	167	32	[	[	-LRB-
cord-313312-h607itv2	167	33	106	106	CD
cord-313312-h607itv2	167	34	]	]	-RRB-
cord-313312-h607itv2	167	35	.	.	.
cord-313312-h607itv2	168	1	More	More	JJR
cord-313312-h607itv2	168	2	mechanistic	mechanistic	JJ
cord-313312-h607itv2	168	3	studies	study	NNS
cord-313312-h607itv2	168	4	will	will	MD
cord-313312-h607itv2	168	5	hence	hence	RB
cord-313312-h607itv2	168	6	be	be	VB
cord-313312-h607itv2	168	7	required	require	VBN
cord-313312-h607itv2	168	8	to	to	TO
cord-313312-h607itv2	168	9	evaluate	evaluate	VB
cord-313312-h607itv2	168	10	the	the	DT
cord-313312-h607itv2	168	11	conditions	condition	NNS
cord-313312-h607itv2	168	12	that	that	WDT
cord-313312-h607itv2	168	13	need	need	VBP
cord-313312-h607itv2	168	14	to	to	TO
cord-313312-h607itv2	168	15	be	be	VB
cord-313312-h607itv2	168	16	satisfied	satisfied	JJ
cord-313312-h607itv2	168	17	to	to	TO
cord-313312-h607itv2	168	18	cause	cause	VB
cord-313312-h607itv2	168	19	B	b	NN
cord-313312-h607itv2	168	20	-	-	HYPH
cord-313312-h607itv2	168	21	cell	cell	NN
cord-313312-h607itv2	168	22	inhibition	inhibition	NN
cord-313312-h607itv2	168	23	.	.	.
cord-313312-h607itv2	169	1	Viruses	virus	NNS
cord-313312-h607itv2	169	2	2020	2020	CD
cord-313312-h607itv2	169	3	,	,	,
cord-313312-h607itv2	169	4	12	12	CD
cord-313312-h607itv2	169	5	,	,	,
cord-313312-h607itv2	169	6	x	x	NN
cord-313312-h607itv2	169	7	FOR	for	IN
cord-313312-h607itv2	169	8	PEER	PEER	NNP
cord-313312-h607itv2	169	9	REVIEW	REVIEW	NNP
cord-313312-h607itv2	169	10	8	8	CD
cord-313312-h607itv2	169	11	of	of	IN
cord-313312-h607itv2	169	12	17	17	CD
cord-313312-h607itv2	170	1	Unlike	unlike	IN
cord-313312-h607itv2	170	2	myeloid	myeloid	NN
cord-313312-h607itv2	170	3	cells	cell	NNS
cord-313312-h607itv2	170	4	,	,	,
cord-313312-h607itv2	170	5	B	b	NN
cord-313312-h607itv2	170	6	-	-	HYPH
cord-313312-h607itv2	170	7	cells	cell	NNS
cord-313312-h607itv2	170	8	exclusively	exclusively	RB
cord-313312-h607itv2	170	9	express	express	VBP
cord-313312-h607itv2	170	10	FcγRIIB	fcγriib	NN
cord-313312-h607itv2	170	11	but	but	CC
cord-313312-h607itv2	170	12	not	not	RB
cord-313312-h607itv2	170	13	the	the	DT
cord-313312-h607itv2	170	14	activating	activate	VBG
cord-313312-h607itv2	170	15	FcγRs	FcγRs	NNP
cord-313312-h607itv2	170	16	[	[	-LRB-
cord-313312-h607itv2	170	17	86	86	CD
cord-313312-h607itv2	170	18	]	]	-RRB-
cord-313312-h607itv2	170	19	.	.	.
cord-313312-h607itv2	171	1	Therefore	therefore	RB
cord-313312-h607itv2	171	2	,	,	,
cord-313312-h607itv2	171	3	cross	cross	NN
cord-313312-h607itv2	171	4	-	-	NN
cord-313312-h607itv2	171	5	linking	linking	NN
cord-313312-h607itv2	171	6	of	of	IN
cord-313312-h607itv2	171	7	the	the	DT
cord-313312-h607itv2	171	8	B	b	NN
cord-313312-h607itv2	171	9	-	-	HYPH
cord-313312-h607itv2	171	10	cell	cell	NN
cord-313312-h607itv2	171	11	receptor	receptor	NN
cord-313312-h607itv2	171	12	(	(	-LRB-
cord-313312-h607itv2	171	13	BCR	BCR	NNP
cord-313312-h607itv2	171	14	)	)	-RRB-
cord-313312-h607itv2	171	15	with	with	IN
cord-313312-h607itv2	171	16	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	171	17	mediated	mediate	VBN
cord-313312-h607itv2	171	18	by	by	IN
cord-313312-h607itv2	171	19	virus	virus	NN
cord-313312-h607itv2	171	20	immune	immune	JJ
cord-313312-h607itv2	171	21	complexes	complex	NNS
cord-313312-h607itv2	171	22	can	can	MD
cord-313312-h607itv2	171	23	lead	lead	VB
cord-313312-h607itv2	171	24	to	to	IN
cord-313312-h607itv2	171	25	the	the	DT
cord-313312-h607itv2	171	26	inhibition	inhibition	NN
cord-313312-h607itv2	171	27	of	of	IN
cord-313312-h607itv2	171	28	B	b	NN
cord-313312-h607itv2	171	29	-	-	HYPH
cord-313312-h607itv2	171	30	cell	cell	NN
cord-313312-h607itv2	171	31	activation	activation	NN
cord-313312-h607itv2	171	32	(	(	-LRB-
cord-313312-h607itv2	171	33	Figure	figure	NN
cord-313312-h607itv2	171	34	2a	2a	CD
cord-313312-h607itv2	171	35	)	)	-RRB-
cord-313312-h607itv2	171	36	.	.	.
cord-313312-h607itv2	172	1	Indeed	indeed	RB
cord-313312-h607itv2	172	2	,	,	,
cord-313312-h607itv2	172	3	by	by	IN
cord-313312-h607itv2	172	4	adding	add	VBG
cord-313312-h607itv2	172	5	sheep	sheep	NNS
cord-313312-h607itv2	172	6	red	red	JJ
cord-313312-h607itv2	172	7	blood	blood	NN
cord-313312-h607itv2	172	8	cell	cell	NN
cord-313312-h607itv2	172	9	-	-	HYPH
cord-313312-h607itv2	172	10	specific	specific	JJ
cord-313312-h607itv2	172	11	(	(	-LRB-
cord-313312-h607itv2	172	12	SBRC	SBRC	NNP
cord-313312-h607itv2	172	13	)	)	-RRB-
cord-313312-h607itv2	172	14	IgG	IgG	NNP
cord-313312-h607itv2	172	15	to	to	TO
cord-313312-h607itv2	172	16	SRBCs	SRBCs	NNP
cord-313312-h607itv2	172	17	,	,	,
cord-313312-h607itv2	172	18	B	b	NN
cord-313312-h607itv2	172	19	-	-	HYPH
cord-313312-h607itv2	172	20	cell	cell	NN
cord-313312-h607itv2	172	21	antibody	antibody	NN
cord-313312-h607itv2	172	22	secretion	secretion	NN
cord-313312-h607itv2	172	23	is	be	VBZ
cord-313312-h607itv2	172	24	reduced	reduce	VBN
cord-313312-h607itv2	172	25	[	[	-LRB-
cord-313312-h607itv2	172	26	104	104	CD
cord-313312-h607itv2	172	27	]	]	-RRB-
cord-313312-h607itv2	172	28	.	.	.
cord-313312-h607itv2	173	1	Similarly	similarly	RB
cord-313312-h607itv2	173	2	,	,	,
cord-313312-h607itv2	173	3	using	use	VBG
cord-313312-h607itv2	173	4	the	the	DT
cord-313312-h607itv2	173	5	cotton	cotton	NN
cord-313312-h607itv2	173	6	rat	rat	NN
cord-313312-h607itv2	173	7	model	model	NN
cord-313312-h607itv2	173	8	of	of	IN
cord-313312-h607itv2	173	9	MV	MV	NNP
cord-313312-h607itv2	173	10	vaccination	vaccination	NN
cord-313312-h607itv2	173	11	,	,	,
cord-313312-h607itv2	173	12	maternal	maternal	JJ
cord-313312-h607itv2	173	13	antibodies	antibody	NNS
cord-313312-h607itv2	173	14	were	be	VBD
cord-313312-h607itv2	173	15	demonstrated	demonstrate	VBN
cord-313312-h607itv2	173	16	to	to	TO
cord-313312-h607itv2	173	17	inhibit	inhibit	VB
cord-313312-h607itv2	173	18	B	b	NN
cord-313312-h607itv2	173	19	-	-	HYPH
cord-313312-h607itv2	173	20	cells	cell	NNS
cord-313312-h607itv2	173	21	by	by	IN
cord-313312-h607itv2	173	22	the	the	DT
cord-313312-h607itv2	173	23	cross	cross	NN
cord-313312-h607itv2	173	24	-	-	JJ
cord-313312-h607itv2	173	25	linking	linking	NN
cord-313312-h607itv2	173	26	of	of	IN
cord-313312-h607itv2	173	27	BCR	BCR	NNP
cord-313312-h607itv2	173	28	and	and	CC
cord-313312-h607itv2	173	29	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	173	30	[	[	-LRB-
cord-313312-h607itv2	173	31	105	105	CD
cord-313312-h607itv2	173	32	]	]	-RRB-
cord-313312-h607itv2	173	33	.	.	.
cord-313312-h607itv2	174	1	However	however	RB
cord-313312-h607itv2	174	2	,	,	,
cord-313312-h607itv2	174	3	this	this	DT
cord-313312-h607itv2	174	4	mechanism	mechanism	NN
cord-313312-h607itv2	174	5	of	of	IN
cord-313312-h607itv2	174	6	inhibition	inhibition	NN
cord-313312-h607itv2	174	7	has	have	VBZ
cord-313312-h607itv2	174	8	not	not	RB
cord-313312-h607itv2	174	9	been	be	VBN
cord-313312-h607itv2	174	10	demonstrated	demonstrate	VBN
cord-313312-h607itv2	174	11	for	for	IN
cord-313312-h607itv2	174	12	other	other	JJ
cord-313312-h607itv2	174	13	viruses	virus	NNS
cord-313312-h607itv2	174	14	.	.	.
cord-313312-h607itv2	175	1	It	-PRON-	PRP
cord-313312-h607itv2	175	2	is	be	VBZ
cord-313312-h607itv2	175	3	conceivable	conceivable	JJ
cord-313312-h607itv2	175	4	that	that	IN
cord-313312-h607itv2	175	5	this	this	DT
cord-313312-h607itv2	175	6	mode	mode	NN
cord-313312-h607itv2	175	7	of	of	IN
cord-313312-h607itv2	175	8	inhibition	inhibition	NN
cord-313312-h607itv2	175	9	is	be	VBZ
cord-313312-h607itv2	175	10	dependent	dependent	JJ
cord-313312-h607itv2	175	11	on	on	IN
cord-313312-h607itv2	175	12	the	the	DT
cord-313312-h607itv2	175	13	size	size	NN
cord-313312-h607itv2	175	14	of	of	IN
cord-313312-h607itv2	175	15	the	the	DT
cord-313312-h607itv2	175	16	virus	virus	NN
cord-313312-h607itv2	175	17	-	-	HYPH
cord-313312-h607itv2	175	18	antibody	antibody	NN
cord-313312-h607itv2	175	19	immune	immune	JJ
cord-313312-h607itv2	175	20	complexes	complex	NNS
cord-313312-h607itv2	175	21	,	,	,
cord-313312-h607itv2	175	22	as	as	IN
cord-313312-h607itv2	175	23	immunization	immunization	NN
cord-313312-h607itv2	175	24	of	of	IN
cord-313312-h607itv2	175	25	small	small	JJ
cord-313312-h607itv2	175	26	polypeptides	polypeptide	NNS
cord-313312-h607itv2	175	27	can	can	MD
cord-313312-h607itv2	175	28	escape	escape	VB
cord-313312-h607itv2	175	29	maternal	maternal	JJ
cord-313312-h607itv2	175	30	antibody	antibody	NN
cord-313312-h607itv2	175	31	inhibition	inhibition	NN
cord-313312-h607itv2	175	32	[	[	-LRB-
cord-313312-h607itv2	175	33	106	106	CD
cord-313312-h607itv2	175	34	]	]	-RRB-
cord-313312-h607itv2	175	35	.	.	.
cord-313312-h607itv2	176	1	More	More	JJR
cord-313312-h607itv2	176	2	mechanistic	mechanistic	JJ
cord-313312-h607itv2	176	3	studies	study	NNS
cord-313312-h607itv2	176	4	will	will	MD
cord-313312-h607itv2	176	5	hence	hence	RB
cord-313312-h607itv2	176	6	be	be	VB
cord-313312-h607itv2	176	7	required	require	VBN
cord-313312-h607itv2	176	8	to	to	TO
cord-313312-h607itv2	176	9	evaluate	evaluate	VB
cord-313312-h607itv2	176	10	the	the	DT
cord-313312-h607itv2	176	11	conditions	condition	NNS
cord-313312-h607itv2	176	12	that	that	WDT
cord-313312-h607itv2	176	13	need	need	VBP
cord-313312-h607itv2	176	14	to	to	TO
cord-313312-h607itv2	176	15	be	be	VB
cord-313312-h607itv2	176	16	satisfied	satisfied	JJ
cord-313312-h607itv2	176	17	to	to	TO
cord-313312-h607itv2	176	18	cause	cause	VB
cord-313312-h607itv2	176	19	B	b	NN
cord-313312-h607itv2	176	20	-	-	HYPH
cord-313312-h607itv2	176	21	cell	cell	NN
cord-313312-h607itv2	176	22	inhibition	inhibition	NN
cord-313312-h607itv2	176	23	.	.	.
cord-313312-h607itv2	177	1	Another	another	DT
cord-313312-h607itv2	177	2	way	way	NN
cord-313312-h607itv2	177	3	in	in	IN
cord-313312-h607itv2	177	4	which	which	WDT
cord-313312-h607itv2	177	5	antibodies	antibody	NNS
cord-313312-h607itv2	177	6	can	can	MD
cord-313312-h607itv2	177	7	inhibit	inhibit	VB
cord-313312-h607itv2	177	8	B	b	NN
cord-313312-h607itv2	177	9	-	-	HYPH
cord-313312-h607itv2	177	10	cell	cell	NN
cord-313312-h607itv2	177	11	responses	response	NNS
cord-313312-h607itv2	177	12	is	be	VBZ
cord-313312-h607itv2	177	13	through	through	IN
cord-313312-h607itv2	177	14	epitope	epitope	NN
cord-313312-h607itv2	177	15	masking	masking	NN
cord-313312-h607itv2	177	16	.	.	.
cord-313312-h607itv2	178	1	This	this	DT
cord-313312-h607itv2	178	2	hypothesis	hypothesis	NN
cord-313312-h607itv2	178	3	postulates	postulate	VBZ
cord-313312-h607itv2	178	4	that	that	IN
cord-313312-h607itv2	178	5	the	the	DT
cord-313312-h607itv2	178	6	presence	presence	NN
cord-313312-h607itv2	178	7	of	of	IN
cord-313312-h607itv2	178	8	pre	pre	JJ
cord-313312-h607itv2	178	9	-	-	JJ
cord-313312-h607itv2	178	10	existing	existing	JJ
cord-313312-h607itv2	178	11	antibodies	antibody	NNS
cord-313312-h607itv2	178	12	can	can	MD
cord-313312-h607itv2	178	13	mask	mask	VB
cord-313312-h607itv2	178	14	the	the	DT
cord-313312-h607itv2	178	15	exposure	exposure	NN
cord-313312-h607itv2	178	16	of	of	IN
cord-313312-h607itv2	178	17	epitopes	epitope	NNS
cord-313312-h607itv2	178	18	,	,	,
cord-313312-h607itv2	178	19	thereby	thereby	RB
cord-313312-h607itv2	178	20	prohibiting	prohibit	VBG
cord-313312-h607itv2	178	21	recognition	recognition	NN
cord-313312-h607itv2	178	22	by	by	IN
cord-313312-h607itv2	178	23	the	the	DT
cord-313312-h607itv2	178	24	B	b	NN
cord-313312-h607itv2	178	25	-	-	HYPH
cord-313312-h607itv2	178	26	cell	cell	NN
cord-313312-h607itv2	178	27	.	.	.
cord-313312-h607itv2	179	1	This	this	DT
cord-313312-h607itv2	179	2	is	be	VBZ
cord-313312-h607itv2	179	3	also	also	RB
cord-313312-h607itv2	179	4	termed	term	VBN
cord-313312-h607itv2	179	5	as	as	IN
cord-313312-h607itv2	179	6	epitope	epitope	NN
cord-313312-h607itv2	179	7	-	-	HYPH
cord-313312-h607itv2	179	8	specific	specific	JJ
cord-313312-h607itv2	179	9	suppression	suppression	NN
cord-313312-h607itv2	179	10	,	,	,
cord-313312-h607itv2	179	11	whereby	whereby	WRB
cord-313312-h607itv2	179	12	epitopes	epitope	NNS
cord-313312-h607itv2	179	13	covered	cover	VBN
cord-313312-h607itv2	179	14	by	by	IN
cord-313312-h607itv2	179	15	these	these	DT
cord-313312-h607itv2	179	16	antibodies	antibody	NNS
cord-313312-h607itv2	179	17	are	be	VBP
cord-313312-h607itv2	179	18	unable	unable	JJ
cord-313312-h607itv2	179	19	to	to	TO
cord-313312-h607itv2	179	20	be	be	VB
cord-313312-h607itv2	179	21	recognized	recognize	VBN
cord-313312-h607itv2	179	22	by	by	IN
cord-313312-h607itv2	179	23	B	b	NN
cord-313312-h607itv2	179	24	-	-	HYPH
cord-313312-h607itv2	179	25	cells	cell	NNS
cord-313312-h607itv2	179	26	(	(	-LRB-
cord-313312-h607itv2	179	27	Figure	figure	NN
cord-313312-h607itv2	179	28	2b	2b	CD
cord-313312-h607itv2	179	29	)	)	-RRB-
cord-313312-h607itv2	179	30	.	.	.
cord-313312-h607itv2	180	1	Interestingly	interestingly	RB
cord-313312-h607itv2	180	2	,	,	,
cord-313312-h607itv2	180	3	there	there	EX
cord-313312-h607itv2	180	4	have	have	VBP
cord-313312-h607itv2	180	5	been	be	VBN
cord-313312-h607itv2	180	6	reports	report	NNS
cord-313312-h607itv2	180	7	of	of	IN
cord-313312-h607itv2	180	8	epitope	epitope	NN
cord-313312-h607itv2	180	9	unspecific	unspecific	JJ
cord-313312-h607itv2	180	10	suppression	suppression	NN
cord-313312-h607itv2	180	11	,	,	,
cord-313312-h607itv2	180	12	where	where	WRB
cord-313312-h607itv2	180	13	monoclonal	monoclonal	JJ
cord-313312-h607itv2	180	14	antibodies	antibody	NNS
cord-313312-h607itv2	180	15	that	that	WDT
cord-313312-h607itv2	180	16	target	target	VBP
cord-313312-h607itv2	180	17	only	only	RB
cord-313312-h607itv2	180	18	one	one	CD
cord-313312-h607itv2	180	19	specific	specific	JJ
cord-313312-h607itv2	180	20	epitope	epitope	NN
cord-313312-h607itv2	180	21	can	can	MD
cord-313312-h607itv2	180	22	suppress	suppress	VB
cord-313312-h607itv2	180	23	B	b	NN
cord-313312-h607itv2	180	24	-	-	HYPH
cord-313312-h607itv2	180	25	cell	cell	NN
cord-313312-h607itv2	180	26	recognition	recognition	NN
cord-313312-h607itv2	180	27	of	of	IN
cord-313312-h607itv2	180	28	a	a	DT
cord-313312-h607itv2	180	29	whole	whole	JJ
cord-313312-h607itv2	180	30	antigen	antigen	NN
cord-313312-h607itv2	180	31	,	,	,
cord-313312-h607itv2	180	32	suggesting	suggest	VBG
cord-313312-h607itv2	180	33	the	the	DT
cord-313312-h607itv2	180	34	possibility	possibility	NN
cord-313312-h607itv2	180	35	that	that	IN
cord-313312-h607itv2	180	36	steric	steric	JJ
cord-313312-h607itv2	180	37	hindrance	hindrance	NN
cord-313312-h607itv2	180	38	or	or	CC
cord-313312-h607itv2	180	39	obstruction	obstruction	NN
cord-313312-h607itv2	180	40	by	by	IN
cord-313312-h607itv2	180	41	high	high	JJ
cord-313312-h607itv2	180	42	concentrations	concentration	NNS
cord-313312-h607itv2	180	43	of	of	IN
cord-313312-h607itv2	180	44	antibodies	antibody	NNS
cord-313312-h607itv2	180	45	can	can	MD
cord-313312-h607itv2	180	46	also	also	RB
cord-313312-h607itv2	180	47	lead	lead	VB
cord-313312-h607itv2	180	48	to	to	IN
cord-313312-h607itv2	180	49	overall	overall	JJ
cord-313312-h607itv2	180	50	suppression	suppression	NN
cord-313312-h607itv2	180	51	B	b	NN
cord-313312-h607itv2	180	52	-	-	HYPH
cord-313312-h607itv2	180	53	cell	cell	NN
cord-313312-h607itv2	180	54	recognition	recognition	NN
cord-313312-h607itv2	180	55	[	[	-LRB-
cord-313312-h607itv2	180	56	107	107	CD
cord-313312-h607itv2	180	57	,	,	,
cord-313312-h607itv2	180	58	108	108	CD
cord-313312-h607itv2	180	59	]	]	-RRB-
cord-313312-h607itv2	180	60	.	.	.
cord-313312-h607itv2	181	1	Antibody	antibody	NN
cord-313312-h607itv2	181	2	-	-	HYPH
cord-313312-h607itv2	181	3	dependent	dependent	JJ
cord-313312-h607itv2	181	4	enhancement	enhancement	NN
cord-313312-h607itv2	181	5	(	(	-LRB-
cord-313312-h607itv2	181	6	ADE	ADE	NNP
cord-313312-h607itv2	181	7	)	)	-RRB-
cord-313312-h607itv2	181	8	of	of	IN
cord-313312-h607itv2	181	9	viral	viral	JJ
cord-313312-h607itv2	181	10	infection	infection	NN
cord-313312-h607itv2	181	11	has	have	VBZ
cord-313312-h607itv2	181	12	been	be	VBN
cord-313312-h607itv2	181	13	documented	document	VBN
cord-313312-h607itv2	181	14	for	for	IN
cord-313312-h607itv2	181	15	many	many	JJ
cord-313312-h607itv2	181	16	viruses	virus	NNS
cord-313312-h607itv2	181	17	,	,	,
cord-313312-h607itv2	181	18	including	include	VBG
cord-313312-h607itv2	181	19	flaviviruses	flavivirus	NNS
cord-313312-h607itv2	181	20	,	,	,
cord-313312-h607itv2	181	21	influenza	influenza	NN
cord-313312-h607itv2	181	22	,	,	,
cord-313312-h607itv2	181	23	MV	MV	NNP
cord-313312-h607itv2	181	24	,	,	,
cord-313312-h607itv2	181	25	Ross	Ross	NNP
cord-313312-h607itv2	181	26	river	river	NN
cord-313312-h607itv2	181	27	viruses	virus	NNS
cord-313312-h607itv2	181	28	,	,	,
cord-313312-h607itv2	181	29	HIV	HIV	NNP
cord-313312-h607itv2	181	30	,	,	,
cord-313312-h607itv2	181	31	and	and	CC
cord-313312-h607itv2	181	32	coronaviruses	coronaviruse	NNS
cord-313312-h607itv2	181	33	[	[	-LRB-
cord-313312-h607itv2	181	34	109	109	CD
cord-313312-h607itv2	181	35	]	]	-RRB-
cord-313312-h607itv2	181	36	.	.	.
cord-313312-h607itv2	182	1	ADE	ADE	NNP
cord-313312-h607itv2	182	2	can	can	MD
cord-313312-h607itv2	182	3	occur	occur	VB
cord-313312-h607itv2	182	4	when	when	WRB
cord-313312-h607itv2	182	5	sub	sub	NN
cord-313312-h607itv2	182	6	-	-	JJ
cord-313312-h607itv2	182	7	neutralizing	neutralize	VBG
cord-313312-h607itv2	182	8	levels	level	NNS
cord-313312-h607itv2	182	9	of	of	IN
cord-313312-h607itv2	182	10	cross	cross	JJ
cord-313312-h607itv2	182	11	-	-	JJ
cord-313312-h607itv2	182	12	reactive	reactive	JJ
cord-313312-h607itv2	182	13	antibodies	antibody	NNS
cord-313312-h607itv2	182	14	form	form	VBP
cord-313312-h607itv2	182	15	immune	immune	JJ
cord-313312-h607itv2	182	16	complexes	complex	NNS
cord-313312-h607itv2	182	17	with	with	IN
cord-313312-h607itv2	182	18	viruses	virus	NNS
cord-313312-h607itv2	182	19	,	,	,
cord-313312-h607itv2	182	20	opsonizing	opsonize	VBG
cord-313312-h607itv2	182	21	viral	viral	JJ
cord-313312-h607itv2	182	22	infection	infection	NN
cord-313312-h607itv2	182	23	in	in	IN
cord-313312-h607itv2	182	24	FcγR	fcγr	NN
cord-313312-h607itv2	182	25	-	-	HYPH
cord-313312-h607itv2	182	26	bearing	bear	VBG
cord-313312-h607itv2	182	27	myeloid	myeloid	NN
cord-313312-h607itv2	182	28	cells	cell	NNS
cord-313312-h607itv2	182	29	including	include	VBG
cord-313312-h607itv2	182	30	monocytes	monocyte	NNS
cord-313312-h607itv2	182	31	,	,	,
cord-313312-h607itv2	182	32	macrophages	macrophage	NNS
cord-313312-h607itv2	182	33	,	,	,
cord-313312-h607itv2	182	34	and	and	CC
cord-313312-h607itv2	182	35	dendritic	dendritic	JJ
cord-313312-h607itv2	182	36	cells	cell	NNS
cord-313312-h607itv2	182	37	via	via	IN
cord-313312-h607itv2	182	38	activating	activate	VBG
cord-313312-h607itv2	182	39	FcγR	fcγr	NN
cord-313312-h607itv2	182	40	-	-	HYPH
cord-313312-h607itv2	182	41	mediated	mediate	VBN
cord-313312-h607itv2	182	42	uptake	uptake	NN
cord-313312-h607itv2	182	43	.	.	.
cord-313312-h607itv2	183	1	The	the	DT
cord-313312-h607itv2	183	2	majority	majority	NN
cord-313312-h607itv2	183	3	of	of	IN
cord-313312-h607itv2	183	4	the	the	DT
cord-313312-h607itv2	183	5	mechanistic	mechanistic	JJ
cord-313312-h607itv2	183	6	insights	insight	NNS
cord-313312-h607itv2	183	7	about	about	IN
cord-313312-h607itv2	183	8	ADE	ADE	NNP
cord-313312-h607itv2	183	9	of	of	IN
cord-313312-h607itv2	183	10	viral	viral	JJ
cord-313312-h607itv2	183	11	infection	infection	NN
cord-313312-h607itv2	183	12	are	be	VBP
cord-313312-h607itv2	183	13	gathered	gather	VBN
cord-313312-h607itv2	183	14	from	from	IN
cord-313312-h607itv2	183	15	dengue	dengue	NN
cord-313312-h607itv2	183	16	,	,	,
cord-313312-h607itv2	183	17	as	as	IN
cord-313312-h607itv2	183	18	waning	wane	VBG
cord-313312-h607itv2	183	19	cross	cross	JJ
cord-313312-h607itv2	183	20	-	-	JJ
cord-313312-h607itv2	183	21	reactive	reactive	JJ
cord-313312-h607itv2	183	22	antibodies	antibody	NNS
cord-313312-h607itv2	183	23	that	that	WDT
cord-313312-h607itv2	183	24	are	be	VBP
cord-313312-h607itv2	183	25	acquired	acquire	VBN
cord-313312-h607itv2	183	26	from	from	IN
cord-313312-h607itv2	183	27	a	a	DT
cord-313312-h607itv2	183	28	heterotypic	heterotypic	NNP
cord-313312-h607itv2	183	29	DENV	DENV	NNP
cord-313312-h607itv2	183	30	infection	infection	NN
cord-313312-h607itv2	183	31	or	or	CC
cord-313312-h607itv2	183	32	through	through	IN
cord-313312-h607itv2	183	33	maternal	maternal	JJ
cord-313312-h607itv2	183	34	-	-	HYPH
cord-313312-h607itv2	183	35	fetal	fetal	JJ
cord-313312-h607itv2	183	36	transmission	transmission	NN
cord-313312-h607itv2	183	37	can	can	MD
cord-313312-h607itv2	183	38	result	result	VB
cord-313312-h607itv2	183	39	in	in	IN
cord-313312-h607itv2	183	40	a	a	DT
cord-313312-h607itv2	183	41	heightened	heightened	JJ
cord-313312-h607itv2	183	42	risk	risk	NN
cord-313312-h607itv2	183	43	of	of	IN
cord-313312-h607itv2	183	44	severe	severe	JJ
cord-313312-h607itv2	183	45	dengue	dengue	NN
cord-313312-h607itv2	183	46	that	that	WDT
cord-313312-h607itv2	183	47	can	can	MD
cord-313312-h607itv2	183	48	be	be	VB
cord-313312-h607itv2	183	49	life	life	NN
cord-313312-h607itv2	183	50	-	-	HYPH
cord-313312-h607itv2	183	51	threatening	threaten	VBG
cord-313312-h607itv2	183	52	[	[	-LRB-
cord-313312-h607itv2	183	53	78	78	CD
cord-313312-h607itv2	183	54	]	]	-RRB-
cord-313312-h607itv2	183	55	[	[	-LRB-
cord-313312-h607itv2	183	56	79	79	CD
cord-313312-h607itv2	183	57	]	]	-RRB-
cord-313312-h607itv2	183	58	[	[	-LRB-
cord-313312-h607itv2	183	59	80	80	CD
cord-313312-h607itv2	183	60	]	]	-RRB-
cord-313312-h607itv2	183	61	.	.	.
cord-313312-h607itv2	184	1	Both	both	DT
cord-313312-h607itv2	184	2	activating	activate	VBG
cord-313312-h607itv2	184	3	FcγRI	FcγRI	NNP
cord-313312-h607itv2	184	4	and	and	CC
cord-313312-h607itv2	184	5	FcγRIIA	FcγRIIA	NNP
cord-313312-h607itv2	184	6	have	have	VBP
cord-313312-h607itv2	184	7	been	be	VBN
cord-313312-h607itv2	184	8	shown	show	VBN
cord-313312-h607itv2	184	9	to	to	TO
cord-313312-h607itv2	184	10	be	be	VB
cord-313312-h607itv2	184	11	involved	involve	VBN
cord-313312-h607itv2	184	12	in	in	IN
cord-313312-h607itv2	184	13	ADE	ade	NN
cord-313312-h607itv2	184	14	-	-	HYPH
cord-313312-h607itv2	184	15	mediated	mediate	VBN
cord-313312-h607itv2	184	16	infection	infection	NN
cord-313312-h607itv2	184	17	,	,	,
cord-313312-h607itv2	184	18	although	although	IN
cord-313312-h607itv2	184	19	increasing	increase	VBG
cord-313312-h607itv2	184	20	studies	study	NNS
cord-313312-h607itv2	184	21	indicate	indicate	VBP
cord-313312-h607itv2	184	22	that	that	IN
cord-313312-h607itv2	184	23	FcγRIIA	FcγRIIA	NNP
cord-313312-h607itv2	184	24	could	could	MD
cord-313312-h607itv2	184	25	be	be	VB
cord-313312-h607itv2	184	26	more	more	RBR
cord-313312-h607itv2	184	27	important	important	JJ
cord-313312-h607itv2	184	28	than	than	IN
cord-313312-h607itv2	184	29	FcγRI	FcγRI	NNP
cord-313312-h607itv2	184	30	in	in	IN
cord-313312-h607itv2	184	31	enhancing	enhance	VBG
cord-313312-h607itv2	184	32	viral	viral	JJ
cord-313312-h607itv2	184	33	infection	infection	NN
cord-313312-h607itv2	184	34	[	[	-LRB-
cord-313312-h607itv2	184	35	110	110	CD
cord-313312-h607itv2	184	36	,	,	,
cord-313312-h607itv2	184	37	111	111	CD
cord-313312-h607itv2	184	38	]	]	-RRB-
cord-313312-h607itv2	184	39	.	.	.
cord-313312-h607itv2	185	1	While	while	IN
cord-313312-h607itv2	185	2	the	the	DT
cord-313312-h607itv2	185	3	precise	precise	JJ
cord-313312-h607itv2	185	4	mechanisms	mechanism	NNS
cord-313312-h607itv2	185	5	involved	involve	VBN
cord-313312-h607itv2	185	6	remain	remain	VBP
cord-313312-h607itv2	185	7	unclear	unclear	JJ
cord-313312-h607itv2	185	8	,	,	,
cord-313312-h607itv2	185	9	it	-PRON-	PRP
cord-313312-h607itv2	185	10	is	be	VBZ
cord-313312-h607itv2	185	11	possible	possible	JJ
cord-313312-h607itv2	185	12	that	that	IN
cord-313312-h607itv2	185	13	the	the	DT
cord-313312-h607itv2	185	14	trafficking	trafficking	NN
cord-313312-h607itv2	185	15	of	of	IN
cord-313312-h607itv2	185	16	immune	immune	JJ
cord-313312-h607itv2	185	17	complexes	complex	NNS
cord-313312-h607itv2	185	18	through	through	IN
cord-313312-h607itv2	185	19	FcγRIIA	fcγriia	NN
cord-313312-h607itv2	185	20	-	-	HYPH
cord-313312-h607itv2	185	21	mediated	mediate	VBN
cord-313312-h607itv2	185	22	uptake	uptake	NN
cord-313312-h607itv2	185	23	is	be	VBZ
cord-313312-h607itv2	185	24	slower	slow	JJR
cord-313312-h607itv2	185	25	,	,	,
cord-313312-h607itv2	185	26	thereby	thereby	RB
cord-313312-h607itv2	185	27	allowing	allow	VBG
cord-313312-h607itv2	185	28	more	more	JJR
cord-313312-h607itv2	185	29	viral	viral	JJ
cord-313312-h607itv2	185	30	fusion	fusion	NN
cord-313312-h607itv2	185	31	and	and	CC
cord-313312-h607itv2	185	32	infection	infection	NN
cord-313312-h607itv2	185	33	[	[	-LRB-
cord-313312-h607itv2	185	34	112	112	CD
cord-313312-h607itv2	185	35	,	,	,
cord-313312-h607itv2	185	36	113	113	CD
cord-313312-h607itv2	185	37	]	]	-RRB-
cord-313312-h607itv2	185	38	.	.	.
cord-313312-h607itv2	186	1	The	the	DT
cord-313312-h607itv2	186	2	activation	activation	NN
cord-313312-h607itv2	186	3	of	of	IN
cord-313312-h607itv2	186	4	FcγRI	FcγRI	NNP
cord-313312-h607itv2	186	5	,	,	,
cord-313312-h607itv2	186	6	however	however	RB
cord-313312-h607itv2	186	7	,	,	,
cord-313312-h607itv2	186	8	may	may	MD
cord-313312-h607itv2	186	9	aid	aid	VB
cord-313312-h607itv2	186	10	to	to	TO
cord-313312-h607itv2	186	11	further	further	RB
cord-313312-h607itv2	186	12	enhance	enhance	VB
cord-313312-h607itv2	186	13	immunogenic	immunogenic	JJ
cord-313312-h607itv2	186	14	responses	response	NNS
cord-313312-h607itv2	186	15	to	to	IN
cord-313312-h607itv2	186	16	viral	viral	JJ
cord-313312-h607itv2	186	17	antigens	antigen	NNS
cord-313312-h607itv2	186	18	by	by	IN
cord-313312-h607itv2	186	19	targeting	target	VBG
cord-313312-h607itv2	186	20	virus	virus	NN
cord-313312-h607itv2	186	21	immune	immune	JJ
cord-313312-h607itv2	186	22	complexes	complex	NNS
cord-313312-h607itv2	186	23	to	to	IN
cord-313312-h607itv2	186	24	the	the	DT
cord-313312-h607itv2	186	25	late	late	JJ
cord-313312-h607itv2	186	26	endosomes	endosome	NNS
cord-313312-h607itv2	186	27	or	or	CC
cord-313312-h607itv2	186	28	lysosomes	lysosome	NNS
cord-313312-h607itv2	186	29	for	for	IN
cord-313312-h607itv2	186	30	enhanced	enhance	VBN
cord-313312-h607itv2	186	31	antigen	antigen	NN
cord-313312-h607itv2	186	32	processing	processing	NN
cord-313312-h607itv2	186	33	and	and	CC
cord-313312-h607itv2	186	34	antigen	antigen	NN
cord-313312-h607itv2	186	35	presentation	presentation	NN
cord-313312-h607itv2	186	36	to	to	IN
cord-313312-h607itv2	186	37	the	the	DT
cord-313312-h607itv2	186	38	CD4	CD4	NNP
cord-313312-h607itv2	186	39	+	+	CC
cord-313312-h607itv2	186	40	T	T	NNP
cord-313312-h607itv2	186	41	-	-	HYPH
cord-313312-h607itv2	186	42	cells	cell	NNS
cord-313312-h607itv2	186	43	,	,	,
cord-313312-h607itv2	186	44	thereby	thereby	RB
cord-313312-h607itv2	186	45	increasing	increase	VBG
cord-313312-h607itv2	186	46	B	b	NN
cord-313312-h607itv2	186	47	-	-	HYPH
cord-313312-h607itv2	186	48	cell	cell	NN
cord-313312-h607itv2	186	49	responses	response	NNS
cord-313312-h607itv2	186	50	[	[	-LRB-
cord-313312-h607itv2	186	51	112	112	CD
cord-313312-h607itv2	186	52	]	]	-RRB-
cord-313312-h607itv2	186	53	.	.	.
cord-313312-h607itv2	187	1	Overall	overall	RB
cord-313312-h607itv2	187	2	,	,	,
cord-313312-h607itv2	187	3	at	at	IN
cord-313312-h607itv2	187	4	sub	sub	NN
cord-313312-h607itv2	187	5	-	-	JJ
cord-313312-h607itv2	187	6	neutralizing	neutralize	VBG
cord-313312-h607itv2	187	7	antibody	antibody	NN
cord-313312-h607itv2	187	8	levels	level	NNS
cord-313312-h607itv2	187	9	,	,	,
cord-313312-h607itv2	187	10	the	the	DT
cord-313312-h607itv2	187	11	presence	presence	NN
cord-313312-h607itv2	187	12	of	of	IN
cord-313312-h607itv2	187	13	pre	pre	JJ
cord-313312-h607itv2	187	14	-	-	JJ
cord-313312-h607itv2	187	15	existing	existing	JJ
cord-313312-h607itv2	187	16	antibodies	antibody	NNS
cord-313312-h607itv2	187	17	can	can	MD
cord-313312-h607itv2	187	18	activate	activate	VB
cord-313312-h607itv2	187	19	both	both	DT
cord-313312-h607itv2	187	20	FcγRI	FcγRI	NNP
cord-313312-h607itv2	187	21	and	and	CC
cord-313312-h607itv2	187	22	FcγRIIA	FcγRIIA	NNP
cord-313312-h607itv2	187	23	,	,	,
cord-313312-h607itv2	187	24	which	which	WDT
cord-313312-h607itv2	187	25	promotes	promote	VBZ
cord-313312-h607itv2	187	26	virus	virus	NN
cord-313312-h607itv2	187	27	uptake	uptake	NN
cord-313312-h607itv2	187	28	,	,	,
cord-313312-h607itv2	187	29	replication	replication	NN
cord-313312-h607itv2	187	30	,	,	,
cord-313312-h607itv2	187	31	and	and	CC
cord-313312-h607itv2	187	32	antigen	antigen	NN
cord-313312-h607itv2	187	33	presentation	presentation	NN
cord-313312-h607itv2	187	34	that	that	WDT
cord-313312-h607itv2	187	35	consequently	consequently	RB
cord-313312-h607itv2	187	36	augments	augment	VBZ
cord-313312-h607itv2	187	37	vaccine	vaccine	NN
cord-313312-h607itv2	187	38	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	187	39	.	.	.
cord-313312-h607itv2	188	1	Besides	besides	IN
cord-313312-h607itv2	188	2	promoting	promote	VBG
cord-313312-h607itv2	188	3	viral	viral	JJ
cord-313312-h607itv2	188	4	entry	entry	NN
cord-313312-h607itv2	188	5	and	and	CC
cord-313312-h607itv2	188	6	antigen	antigen	NN
cord-313312-h607itv2	188	7	presentation	presentation	NN
cord-313312-h607itv2	188	8	,	,	,
cord-313312-h607itv2	188	9	the	the	DT
cord-313312-h607itv2	188	10	cross	cross	NN
cord-313312-h607itv2	188	11	-	-	NN
cord-313312-h607itv2	188	12	linking	linking	NN
cord-313312-h607itv2	188	13	of	of	IN
cord-313312-h607itv2	188	14	FcγRs	FcγRs	NNP
cord-313312-h607itv2	188	15	may	may	MD
cord-313312-h607itv2	188	16	also	also	RB
cord-313312-h607itv2	188	17	modulate	modulate	VB
cord-313312-h607itv2	188	18	cellular	cellular	JJ
cord-313312-h607itv2	188	19	and	and	CC
cord-313312-h607itv2	188	20	host	host	NN
cord-313312-h607itv2	188	21	responses	response	NNS
cord-313312-h607itv2	188	22	that	that	WDT
cord-313312-h607itv2	188	23	promote	promote	VBP
cord-313312-h607itv2	188	24	viral	viral	JJ
cord-313312-h607itv2	188	25	replication	replication	NN
cord-313312-h607itv2	188	26	and	and	CC
cord-313312-h607itv2	188	27	LAV	LAV	NNP
cord-313312-h607itv2	188	28	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	188	29	(	(	-LRB-
cord-313312-h607itv2	188	30	Figure	figure	NN
cord-313312-h607itv2	188	31	3	3	CD
cord-313312-h607itv2	188	32	)	)	-RRB-
cord-313312-h607itv2	188	33	.	.	.
cord-313312-h607itv2	189	1	Some	some	DT
cord-313312-h607itv2	189	2	insights	insight	NNS
cord-313312-h607itv2	189	3	can	can	MD
cord-313312-h607itv2	189	4	be	be	VB
cord-313312-h607itv2	189	5	obtained	obtain	VBN
cord-313312-h607itv2	189	6	from	from	IN
cord-313312-h607itv2	189	7	our	-PRON-	PRP$
cord-313312-h607itv2	189	8	clinical	clinical	JJ
cord-313312-h607itv2	189	9	trial	trial	NN
cord-313312-h607itv2	189	10	,	,	,
cord-313312-h607itv2	189	11	where	where	WRB
cord-313312-h607itv2	189	12	subjects	subject	NNS
cord-313312-h607itv2	189	13	were	be	VBD
cord-313312-h607itv2	189	14	sequentially	sequentially	RB
cord-313312-h607itv2	189	15	vaccinated	vaccinate	VBN
cord-313312-h607itv2	189	16	with	with	IN
cord-313312-h607itv2	189	17	the	the	DT
cord-313312-h607itv2	189	18	inactivated	inactivate	VBN
cord-313312-h607itv2	189	19	Japanese	Japanese	NNP
cord-313312-h607itv2	189	20	Encephalitis	Encephalitis	NNP
cord-313312-h607itv2	189	21	virus	virus	NN
cord-313312-h607itv2	189	22	vaccine	vaccine	NN
cord-313312-h607itv2	189	23	followed	follow	VBN
cord-313312-h607itv2	189	24	by	by	IN
cord-313312-h607itv2	189	25	the	the	DT
cord-313312-h607itv2	189	26	yellow	yellow	JJ
cord-313312-h607itv2	189	27	fever	fever	NNP
cord-313312-h607itv2	189	28	vaccine	vaccine	NN
cord-313312-h607itv2	189	29	.	.	.
cord-313312-h607itv2	190	1	Subjects	subject	NNS
cord-313312-h607itv2	190	2	within	within	IN
cord-313312-h607itv2	190	3	a	a	DT
cord-313312-h607itv2	190	4	restricted	restricted	JJ
cord-313312-h607itv2	190	5	range	range	NN
cord-313312-h607itv2	190	6	of	of	IN
cord-313312-h607itv2	190	7	cross	cross	JJ
cord-313312-h607itv2	190	8	-	-	JJ
cord-313312-h607itv2	190	9	reactive	reactive	JJ
cord-313312-h607itv2	190	10	antibodies	antibody	NNS
cord-313312-h607itv2	190	11	resulted	result	VBD
cord-313312-h607itv2	190	12	in	in	IN
cord-313312-h607itv2	190	13	increased	increase	VBN
cord-313312-h607itv2	190	14	antibody	antibody	NN
cord-313312-h607itv2	190	15	responses	response	NNS
cord-313312-h607itv2	190	16	,	,	,
cord-313312-h607itv2	190	17	whereas	whereas	IN
cord-313312-h607itv2	190	18	too	too	RB
cord-313312-h607itv2	190	19	many	many	JJ
cord-313312-h607itv2	190	20	or	or	CC
cord-313312-h607itv2	190	21	too	too	RB
cord-313312-h607itv2	190	22	few	few	JJ
cord-313312-h607itv2	190	23	antibodies	antibody	NNS
cord-313312-h607itv2	190	24	resulted	result	VBD
cord-313312-h607itv2	190	25	in	in	IN
cord-313312-h607itv2	190	26	reduced	reduce	VBN
cord-313312-h607itv2	190	27	antibody	antibody	NN
cord-313312-h607itv2	190	28	responses	response	NNS
cord-313312-h607itv2	190	29	,	,	,
cord-313312-h607itv2	190	30	indicating	indicate	VBG
cord-313312-h607itv2	190	31	the	the	DT
cord-313312-h607itv2	190	32	possible	possible	JJ
cord-313312-h607itv2	190	33	role	role	NN
cord-313312-h607itv2	190	34	of	of	IN
cord-313312-h607itv2	190	35	ADE	ADE	NNP
cord-313312-h607itv2	190	36	in	in	IN
cord-313312-h607itv2	190	37	augmented	augment	VBN
cord-313312-h607itv2	190	38	vaccine	vaccine	NN
cord-313312-h607itv2	190	39	antibody	antibody	NN
cord-313312-h607itv2	190	40	responses	response	NNS
cord-313312-h607itv2	190	41	[	[	-LRB-
cord-313312-h607itv2	190	42	85	85	CD
cord-313312-h607itv2	190	43	]	]	-RRB-
cord-313312-h607itv2	190	44	.	.	.
cord-313312-h607itv2	191	1	In	in	IN
cord-313312-h607itv2	191	2	addition	addition	NN
cord-313312-h607itv2	191	3	to	to	IN
cord-313312-h607itv2	191	4	the	the	DT
cord-313312-h607itv2	191	5	extended	extended	JJ
cord-313312-h607itv2	191	6	duration	duration	NN
cord-313312-h607itv2	191	7	of	of	IN
cord-313312-h607itv2	191	8	viremia	viremia	NN
cord-313312-h607itv2	191	9	observed	observe	VBN
cord-313312-h607itv2	191	10	in	in	IN
cord-313312-h607itv2	191	11	these	these	DT
cord-313312-h607itv2	191	12	subjects	subject	NNS
cord-313312-h607itv2	191	13	,	,	,
cord-313312-h607itv2	191	14	enhancing	enhance	VBG
cord-313312-h607itv2	191	15	titers	titer	NNS
cord-313312-h607itv2	191	16	of	of	IN
cord-313312-h607itv2	191	17	cross	cross	JJ
cord-313312-h607itv2	191	18	-	-	JJ
cord-313312-h607itv2	191	19	reactive	reactive	JJ
cord-313312-h607itv2	191	20	antibodies	antibody	NNS
cord-313312-h607itv2	191	21	provoked	provoke	VBD
cord-313312-h607itv2	191	22	greater	great	JJR
cord-313312-h607itv2	191	23	pro	pro	JJ
cord-313312-h607itv2	191	24	-	-	JJ
cord-313312-h607itv2	191	25	inflammatory	inflammatory	JJ
cord-313312-h607itv2	191	26	responses	response	NNS
cord-313312-h607itv2	191	27	,	,	,
cord-313312-h607itv2	191	28	including	include	VBG
cord-313312-h607itv2	191	29	increased	increase	VBN
cord-313312-h607itv2	191	30	innate	innate	JJ
cord-313312-h607itv2	191	31	immune	immune	JJ
cord-313312-h607itv2	191	32	responses	response	NNS
cord-313312-h607itv2	191	33	and	and	CC
cord-313312-h607itv2	191	34	the	the	DT
cord-313312-h607itv2	191	35	production	production	NN
cord-313312-h607itv2	191	36	of	of	IN
cord-313312-h607itv2	191	37	pro	pro	JJ
cord-313312-h607itv2	191	38	-	-	JJ
cord-313312-h607itv2	191	39	inflammatory	inflammatory	JJ
cord-313312-h607itv2	191	40	metabolites	metabolite	NNS
cord-313312-h607itv2	191	41	such	such	JJ
cord-313312-h607itv2	191	42	as	as	IN
cord-313312-h607itv2	191	43	arachidonic	arachidonic	JJ
cord-313312-h607itv2	191	44	acid	acid	NN
cord-313312-h607itv2	191	45	,	,	,
cord-313312-h607itv2	191	46	linoleic	linoleic	JJ
cord-313312-h607itv2	191	47	acid	acid	NN
cord-313312-h607itv2	191	48	,	,	,
cord-313312-h607itv2	191	49	and	and	CC
cord-313312-h607itv2	191	50	12-HETE	12-hete	CD
cord-313312-h607itv2	191	51	that	that	WDT
cord-313312-h607itv2	191	52	promote	promote	VBP
cord-313312-h607itv2	191	53	phagocytosis	phagocytosis	NN
cord-313312-h607itv2	191	54	and	and	CC
cord-313312-h607itv2	191	55	adaptive	adaptive	JJ
cord-313312-h607itv2	191	56	immune	immune	JJ
cord-313312-h607itv2	191	57	responses	response	NNS
cord-313312-h607itv2	191	58	.	.	.
cord-313312-h607itv2	192	1	The	the	DT
cord-313312-h607itv2	192	2	co	co	NN
cord-313312-h607itv2	192	3	-	-	NN
cord-313312-h607itv2	192	4	ligation	ligation	NN
cord-313312-h607itv2	192	5	of	of	IN
cord-313312-h607itv2	192	6	both	both	DT
cord-313312-h607itv2	192	7	FcγRI	FcγRI	NNP
cord-313312-h607itv2	192	8	and	and	CC
cord-313312-h607itv2	192	9	FcγRIIA	FcγRIIA	NNP
cord-313312-h607itv2	192	10	by	by	IN
cord-313312-h607itv2	192	11	virus	virus	NN
cord-313312-h607itv2	192	12	-	-	HYPH
cord-313312-h607itv2	192	13	antibody	antibody	NN
cord-313312-h607itv2	192	14	immune	immune	JJ
cord-313312-h607itv2	192	15	complexes	complex	NNS
cord-313312-h607itv2	192	16	or	or	CC
cord-313312-h607itv2	192	17	cross	cross	NN
cord-313312-h607itv2	192	18	-	-	NN
cord-313312-h607itv2	192	19	linking	linking	NN
cord-313312-h607itv2	192	20	can	can	MD
cord-313312-h607itv2	192	21	also	also	RB
cord-313312-h607itv2	192	22	upregulate	upregulate	VB
cord-313312-h607itv2	192	23	immune	immune	JJ
cord-313312-h607itv2	192	24	semaphorins	semaphorin	NNS
cord-313312-h607itv2	192	25	such	such	JJ
cord-313312-h607itv2	192	26	as	as	IN
cord-313312-h607itv2	192	27	SEMA4A	SEMA4A	NNP
cord-313312-h607itv2	192	28	,	,	,
cord-313312-h607itv2	192	29	SEMA6A	SEMA6A	NNP
cord-313312-h607itv2	192	30	,	,	,
cord-313312-h607itv2	192	31	and	and	CC
cord-313312-h607itv2	192	32	SEMA7A	SEMA7A	NNP
cord-313312-h607itv2	192	33	which	which	WDT
cord-313312-h607itv2	192	34	are	be	VBP
cord-313312-h607itv2	192	35	critical	critical	JJ
cord-313312-h607itv2	192	36	for	for	IN
cord-313312-h607itv2	192	37	antigen	antigen	NN
cord-313312-h607itv2	192	38	-	-	HYPH
cord-313312-h607itv2	192	39	presenting	present	VBG
cord-313312-h607itv2	192	40	cell	cell	NN
cord-313312-h607itv2	192	41	and	and	CC
cord-313312-h607itv2	192	42	T	t	NN
cord-313312-h607itv2	192	43	-	-	HYPH
cord-313312-h607itv2	192	44	cell	cell	NN
cord-313312-h607itv2	192	45	interactions	interaction	NNS
cord-313312-h607itv2	192	46	[	[	-LRB-
cord-313312-h607itv2	192	47	85	85	CD
cord-313312-h607itv2	192	48	]	]	-RRB-
cord-313312-h607itv2	192	49	.	.	.
cord-313312-h607itv2	193	1	While	while	IN
cord-313312-h607itv2	193	2	the	the	DT
cord-313312-h607itv2	193	3	mechanisms	mechanism	NNS
cord-313312-h607itv2	193	4	of	of	IN
cord-313312-h607itv2	193	5	whether	whether	IN
cord-313312-h607itv2	193	6	upregulation	upregulation	NN
cord-313312-h607itv2	193	7	of	of	IN
cord-313312-h607itv2	193	8	immune	immune	JJ
cord-313312-h607itv2	193	9	semaphorins	semaphorin	NNS
cord-313312-h607itv2	193	10	by	by	IN
cord-313312-h607itv2	193	11	immune	immune	JJ
cord-313312-h607itv2	193	12	complexes	complex	NNS
cord-313312-h607itv2	193	13	leads	lead	VBZ
cord-313312-h607itv2	193	14	to	to	IN
cord-313312-h607itv2	193	15	increased	increase	VBN
cord-313312-h607itv2	193	16	T	t	NN
cord-313312-h607itv2	193	17	-	-	HYPH
cord-313312-h607itv2	193	18	cell	cell	NN
cord-313312-h607itv2	193	19	proliferation	proliferation	NN
cord-313312-h607itv2	193	20	and	and	CC
cord-313312-h607itv2	193	21	activation	activation	NN
cord-313312-h607itv2	193	22	in	in	IN
cord-313312-h607itv2	193	23	humans	human	NNS
cord-313312-h607itv2	193	24	remains	remain	VBZ
cord-313312-h607itv2	193	25	to	to	TO
cord-313312-h607itv2	193	26	be	be	VB
cord-313312-h607itv2	193	27	evaluated	evaluate	VBN
cord-313312-h607itv2	193	28	,	,	,
cord-313312-h607itv2	193	29	previous	previous	JJ
cord-313312-h607itv2	193	30	studies	study	NNS
cord-313312-h607itv2	193	31	have	have	VBP
cord-313312-h607itv2	193	32	shown	show	VBN
cord-313312-h607itv2	193	33	that	that	IN
cord-313312-h607itv2	193	34	SEMA4A	SEMA4A	NNP
cord-313312-h607itv2	193	35	can	can	MD
cord-313312-h607itv2	193	36	enhance	enhance	VB
cord-313312-h607itv2	193	37	T	T	NNP
cord-313312-h607itv2	193	38	-	-	HYPH
cord-313312-h607itv2	193	39	cell	cell	NN
cord-313312-h607itv2	193	40	activation	activation	NN
cord-313312-h607itv2	193	41	through	through	IN
cord-313312-h607itv2	193	42	interaction	interaction	NN
cord-313312-h607itv2	193	43	with	with	IN
cord-313312-h607itv2	193	44	Tim-2	Tim-2	NNP
cord-313312-h607itv2	193	45	,	,	,
cord-313312-h607itv2	193	46	thereby	thereby	RB
cord-313312-h607itv2	193	47	increasing	increase	VBG
cord-313312-h607itv2	193	48	antigen	antigen	NN
cord-313312-h607itv2	193	49	-	-	HYPH
cord-313312-h607itv2	193	50	specific	specific	JJ
cord-313312-h607itv2	193	51	T	t	NN
cord-313312-h607itv2	193	52	-	-	HYPH
cord-313312-h607itv2	193	53	cell	cell	NN
cord-313312-h607itv2	193	54	and	and	CC
cord-313312-h607itv2	193	55	antibody	antibody	NN
cord-313312-h607itv2	193	56	responses	response	NNS
cord-313312-h607itv2	193	57	against	against	IN
cord-313312-h607itv2	193	58	T	t	NN
cord-313312-h607itv2	193	59	-	-	HYPH
cord-313312-h607itv2	193	60	cell	cell	NN
cord-313312-h607itv2	193	61	dependent	dependent	JJ
cord-313312-h607itv2	193	62	antigens	antigen	NNS
cord-313312-h607itv2	193	63	[	[	-LRB-
cord-313312-h607itv2	193	64	114	114	CD
cord-313312-h607itv2	193	65	,	,	,
cord-313312-h607itv2	193	66	115	115	CD
cord-313312-h607itv2	193	67	]	]	-RRB-
cord-313312-h607itv2	193	68	.	.	.
cord-313312-h607itv2	194	1	However	however	RB
cord-313312-h607itv2	194	2	,	,	,
cord-313312-h607itv2	194	3	it	-PRON-	PRP
cord-313312-h607itv2	194	4	is	be	VBZ
cord-313312-h607itv2	194	5	also	also	RB
cord-313312-h607itv2	194	6	noticeable	noticeable	JJ
cord-313312-h607itv2	194	7	that	that	IN
cord-313312-h607itv2	194	8	not	not	RB
cord-313312-h607itv2	194	9	all	all	DT
cord-313312-h607itv2	194	10	subjects	subject	NNS
cord-313312-h607itv2	194	11	within	within	IN
cord-313312-h607itv2	194	12	that	that	DT
cord-313312-h607itv2	194	13	specific	specific	JJ
cord-313312-h607itv2	194	14	window	window	NN
cord-313312-h607itv2	194	15	of	of	IN
cord-313312-h607itv2	194	16	cross	cross	JJ
cord-313312-h607itv2	194	17	-	-	JJ
cord-313312-h607itv2	194	18	reactive	reactive	JJ
cord-313312-h607itv2	194	19	antibody	antibody	NN
cord-313312-h607itv2	194	20	levels	level	NNS
cord-313312-h607itv2	194	21	exhibited	exhibit	VBD
cord-313312-h607itv2	194	22	increased	increased	JJ
cord-313312-h607itv2	194	23	vaccine	vaccine	NN
cord-313312-h607itv2	194	24	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	194	25	,	,	,
cord-313312-h607itv2	194	26	suggesting	suggest	VBG
cord-313312-h607itv2	194	27	that	that	IN
cord-313312-h607itv2	194	28	baseline	baseline	JJ
cord-313312-h607itv2	194	29	variations	variation	NNS
cord-313312-h607itv2	194	30	,	,	,
cord-313312-h607itv2	194	31	such	such	JJ
cord-313312-h607itv2	194	32	as	as	IN
cord-313312-h607itv2	194	33	genetics	genetic	NNS
cord-313312-h607itv2	194	34	,	,	,
cord-313312-h607itv2	194	35	dietary	dietary	JJ
cord-313312-h607itv2	194	36	or	or	CC
cord-313312-h607itv2	194	37	environmental	environmental	JJ
cord-313312-h607itv2	194	38	factors	factor	NNS
cord-313312-h607itv2	194	39	may	may	MD
cord-313312-h607itv2	194	40	also	also	RB
cord-313312-h607itv2	194	41	influence	influence	VB
cord-313312-h607itv2	194	42	the	the	DT
cord-313312-h607itv2	194	43	outcome	outcome	NN
cord-313312-h607itv2	194	44	of	of	IN
cord-313312-h607itv2	194	45	LAV	LAV	NNP
cord-313312-h607itv2	194	46	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	194	47	[	[	-LRB-
cord-313312-h607itv2	194	48	85	85	CD
cord-313312-h607itv2	194	49	]	]	-RRB-
cord-313312-h607itv2	194	50	.	.	.
cord-313312-h607itv2	195	1	Some	some	DT
cord-313312-h607itv2	195	2	recent	recent	JJ
cord-313312-h607itv2	195	3	studies	study	NNS
cord-313312-h607itv2	195	4	hinted	hint	VBD
cord-313312-h607itv2	195	5	at	at	IN
cord-313312-h607itv2	195	6	the	the	DT
cord-313312-h607itv2	195	7	possibility	possibility	NN
cord-313312-h607itv2	195	8	that	that	IN
cord-313312-h607itv2	195	9	baseline	baseline	JJ
cord-313312-h607itv2	195	10	variations	variation	NNS
cord-313312-h607itv2	195	11	in	in	IN
cord-313312-h607itv2	195	12	B	b	NN
cord-313312-h607itv2	195	13	-	-	HYPH
cord-313312-h607itv2	195	14	cell	cell	NN
cord-313312-h607itv2	195	15	signatures	signature	NNS
cord-313312-h607itv2	195	16	and	and	CC
cord-313312-h607itv2	195	17	gene	gene	NN
cord-313312-h607itv2	195	18	regulation	regulation	NN
cord-313312-h607itv2	195	19	could	could	MD
cord-313312-h607itv2	195	20	influence	influence	VB
cord-313312-h607itv2	195	21	LAV	LAV	NNP
cord-313312-h607itv2	195	22	reactogenicity	reactogenicity	NN
cord-313312-h607itv2	195	23	and	and	CC
cord-313312-h607itv2	195	24	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	195	25	,	,	,
cord-313312-h607itv2	195	26	which	which	WDT
cord-313312-h607itv2	195	27	can	can	MD
cord-313312-h607itv2	195	28	be	be	VB
cord-313312-h607itv2	195	29	potential	potential	JJ
cord-313312-h607itv2	195	30	avenues	avenue	NNS
cord-313312-h607itv2	195	31	for	for	IN
cord-313312-h607itv2	195	32	future	future	JJ
cord-313312-h607itv2	195	33	studies	study	NNS
cord-313312-h607itv2	195	34	[	[	-LRB-
cord-313312-h607itv2	195	35	116	116	CD
cord-313312-h607itv2	195	36	,	,	,
cord-313312-h607itv2	195	37	117	117	CD
cord-313312-h607itv2	195	38	]	]	-RRB-
cord-313312-h607itv2	195	39	.	.	.
cord-313312-h607itv2	196	1	Viruses	virus	NNS
cord-313312-h607itv2	196	2	2020	2020	CD
cord-313312-h607itv2	196	3	,	,	,
cord-313312-h607itv2	196	4	12	12	CD
cord-313312-h607itv2	196	5	,	,	,
cord-313312-h607itv2	196	6	x	x	NN
cord-313312-h607itv2	196	7	FOR	for	IN
cord-313312-h607itv2	196	8	PEER	peer	NN
cord-313312-h607itv2	196	9	REVIEW	review	NN
cord-313312-h607itv2	197	1	10	10	CD
cord-313312-h607itv2	197	2	of	of	IN
cord-313312-h607itv2	197	3	17	17	CD
cord-313312-h607itv2	197	4	cell	cell	NN
cord-313312-h607itv2	197	5	dependent	dependent	JJ
cord-313312-h607itv2	197	6	antigens	antigen	NNS
cord-313312-h607itv2	197	7	[	[	-LRB-
cord-313312-h607itv2	197	8	114	114	CD
cord-313312-h607itv2	197	9	,	,	,
cord-313312-h607itv2	197	10	115	115	CD
cord-313312-h607itv2	197	11	]	]	-RRB-
cord-313312-h607itv2	197	12	.	.	.
cord-313312-h607itv2	198	1	However	however	RB
cord-313312-h607itv2	198	2	,	,	,
cord-313312-h607itv2	198	3	it	-PRON-	PRP
cord-313312-h607itv2	198	4	is	be	VBZ
cord-313312-h607itv2	198	5	also	also	RB
cord-313312-h607itv2	198	6	noticeable	noticeable	JJ
cord-313312-h607itv2	198	7	that	that	IN
cord-313312-h607itv2	198	8	not	not	RB
cord-313312-h607itv2	198	9	all	all	DT
cord-313312-h607itv2	198	10	subjects	subject	NNS
cord-313312-h607itv2	198	11	within	within	IN
cord-313312-h607itv2	198	12	that	that	DT
cord-313312-h607itv2	198	13	specific	specific	JJ
cord-313312-h607itv2	198	14	window	window	NN
cord-313312-h607itv2	198	15	of	of	IN
cord-313312-h607itv2	198	16	cross	cross	JJ
cord-313312-h607itv2	198	17	-	-	JJ
cord-313312-h607itv2	198	18	reactive	reactive	JJ
cord-313312-h607itv2	198	19	antibody	antibody	NN
cord-313312-h607itv2	198	20	levels	level	NNS
cord-313312-h607itv2	198	21	exhibited	exhibit	VBD
cord-313312-h607itv2	198	22	increased	increased	JJ
cord-313312-h607itv2	198	23	vaccine	vaccine	NN
cord-313312-h607itv2	198	24	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	198	25	,	,	,
cord-313312-h607itv2	198	26	suggesting	suggest	VBG
cord-313312-h607itv2	198	27	that	that	IN
cord-313312-h607itv2	198	28	baseline	baseline	JJ
cord-313312-h607itv2	198	29	variations	variation	NNS
cord-313312-h607itv2	198	30	,	,	,
cord-313312-h607itv2	198	31	such	such	JJ
cord-313312-h607itv2	198	32	as	as	IN
cord-313312-h607itv2	198	33	genetics	genetic	NNS
cord-313312-h607itv2	198	34	,	,	,
cord-313312-h607itv2	198	35	dietary	dietary	JJ
cord-313312-h607itv2	198	36	or	or	CC
cord-313312-h607itv2	198	37	environmental	environmental	JJ
cord-313312-h607itv2	198	38	factors	factor	NNS
cord-313312-h607itv2	198	39	may	may	MD
cord-313312-h607itv2	198	40	also	also	RB
cord-313312-h607itv2	198	41	influence	influence	VB
cord-313312-h607itv2	198	42	the	the	DT
cord-313312-h607itv2	198	43	outcome	outcome	NN
cord-313312-h607itv2	198	44	of	of	IN
cord-313312-h607itv2	198	45	LAV	LAV	NNP
cord-313312-h607itv2	198	46	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	198	47	[	[	-LRB-
cord-313312-h607itv2	198	48	85	85	CD
cord-313312-h607itv2	198	49	]	]	-RRB-
cord-313312-h607itv2	198	50	.	.	.
cord-313312-h607itv2	199	1	Some	some	DT
cord-313312-h607itv2	199	2	recent	recent	JJ
cord-313312-h607itv2	199	3	studies	study	NNS
cord-313312-h607itv2	199	4	hinted	hint	VBD
cord-313312-h607itv2	199	5	at	at	IN
cord-313312-h607itv2	199	6	the	the	DT
cord-313312-h607itv2	199	7	possibility	possibility	NN
cord-313312-h607itv2	199	8	that	that	IN
cord-313312-h607itv2	199	9	baseline	baseline	JJ
cord-313312-h607itv2	199	10	variations	variation	NNS
cord-313312-h607itv2	199	11	in	in	IN
cord-313312-h607itv2	199	12	B	b	NN
cord-313312-h607itv2	199	13	-	-	HYPH
cord-313312-h607itv2	199	14	cell	cell	NN
cord-313312-h607itv2	199	15	signatures	signature	NNS
cord-313312-h607itv2	199	16	and	and	CC
cord-313312-h607itv2	199	17	gene	gene	NN
cord-313312-h607itv2	199	18	regulation	regulation	NN
cord-313312-h607itv2	199	19	could	could	MD
cord-313312-h607itv2	199	20	influence	influence	VB
cord-313312-h607itv2	199	21	LAV	LAV	NNP
cord-313312-h607itv2	199	22	reactogenicity	reactogenicity	NN
cord-313312-h607itv2	199	23	and	and	CC
cord-313312-h607itv2	199	24	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	199	25	,	,	,
cord-313312-h607itv2	199	26	which	which	WDT
cord-313312-h607itv2	199	27	can	can	MD
cord-313312-h607itv2	199	28	be	be	VB
cord-313312-h607itv2	199	29	potential	potential	JJ
cord-313312-h607itv2	199	30	avenues	avenue	NNS
cord-313312-h607itv2	199	31	for	for	IN
cord-313312-h607itv2	199	32	future	future	JJ
cord-313312-h607itv2	199	33	studies	study	NNS
cord-313312-h607itv2	199	34	[	[	-LRB-
cord-313312-h607itv2	199	35	116	116	CD
cord-313312-h607itv2	199	36	,	,	,
cord-313312-h607itv2	199	37	117	117	CD
cord-313312-h607itv2	199	38	]	]	-RRB-
cord-313312-h607itv2	199	39	.	.	.
cord-313312-h607itv2	200	1	Immune	immune	JJ
cord-313312-h607itv2	200	2	complexes	complex	NNS
cord-313312-h607itv2	200	3	formed	form	VBN
cord-313312-h607itv2	200	4	by	by	IN
cord-313312-h607itv2	200	5	pre	pre	JJ
cord-313312-h607itv2	200	6	-	-	JJ
cord-313312-h607itv2	200	7	existing	existing	JJ
cord-313312-h607itv2	200	8	antibodies	antibody	NNS
cord-313312-h607itv2	200	9	and	and	CC
cord-313312-h607itv2	200	10	viruses	virus	NNS
cord-313312-h607itv2	200	11	can	can	MD
cord-313312-h607itv2	200	12	engage	engage	VB
cord-313312-h607itv2	200	13	FcγRs	FcγRs	NNP
cord-313312-h607itv2	200	14	,	,	,
cord-313312-h607itv2	200	15	resulting	result	VBG
cord-313312-h607itv2	200	16	in	in	IN
cord-313312-h607itv2	200	17	increased	increase	VBN
cord-313312-h607itv2	200	18	viral	viral	JJ
cord-313312-h607itv2	200	19	uptake	uptake	NN
cord-313312-h607itv2	200	20	and	and	CC
cord-313312-h607itv2	200	21	fusion	fusion	NN
cord-313312-h607itv2	200	22	through	through	IN
cord-313312-h607itv2	200	23	the	the	DT
cord-313312-h607itv2	200	24	process	process	NN
cord-313312-h607itv2	200	25	of	of	IN
cord-313312-h607itv2	200	26	antibody	antibody	NN
cord-313312-h607itv2	200	27	-	-	HYPH
cord-313312-h607itv2	200	28	dependent	dependent	JJ
cord-313312-h607itv2	200	29	enhancement	enhancement	NN
cord-313312-h607itv2	200	30	that	that	WDT
cord-313312-h607itv2	200	31	leads	lead	VBZ
cord-313312-h607itv2	200	32	to	to	IN
cord-313312-h607itv2	200	33	increased	increase	VBN
cord-313312-h607itv2	200	34	vaccine	vaccine	NN
cord-313312-h607itv2	200	35	viremia	viremia	NN
cord-313312-h607itv2	200	36	and	and	CC
cord-313312-h607itv2	200	37	antigen	antigen	NN
cord-313312-h607itv2	200	38	presentation	presentation	NN
cord-313312-h607itv2	200	39	.	.	.
cord-313312-h607itv2	201	1	Activating	activate	VBG
cord-313312-h607itv2	201	2	FcγR	fcγr	NN
cord-313312-h607itv2	201	3	-	-	HYPH
cord-313312-h607itv2	201	4	signaling	signal	VBG
cord-313312-h607itv2	201	5	,	,	,
cord-313312-h607itv2	201	6	on	on	IN
cord-313312-h607itv2	201	7	the	the	DT
cord-313312-h607itv2	201	8	other	other	JJ
cord-313312-h607itv2	201	9	hand	hand	NN
cord-313312-h607itv2	201	10	,	,	,
cord-313312-h607itv2	201	11	provokes	provoke	VBZ
cord-313312-h607itv2	201	12	greater	great	JJR
cord-313312-h607itv2	201	13	innate	innate	JJ
cord-313312-h607itv2	201	14	immune	immune	JJ
cord-313312-h607itv2	201	15	responses	response	NNS
cord-313312-h607itv2	201	16	and	and	CC
cord-313312-h607itv2	201	17	production	production	NN
cord-313312-h607itv2	201	18	of	of	IN
cord-313312-h607itv2	201	19	pro	pro	JJ
cord-313312-h607itv2	201	20	-	-	JJ
cord-313312-h607itv2	201	21	inflammatory	inflammatory	JJ
cord-313312-h607itv2	201	22	metabolites	metabolite	NNS
cord-313312-h607itv2	201	23	that	that	WDT
cord-313312-h607itv2	201	24	can	can	MD
cord-313312-h607itv2	201	25	enhance	enhance	VB
cord-313312-h607itv2	201	26	innate	innate	JJ
cord-313312-h607itv2	201	27	and	and	CC
cord-313312-h607itv2	201	28	adaptive	adaptive	JJ
cord-313312-h607itv2	201	29	immune	immune	JJ
cord-313312-h607itv2	201	30	responses	response	NNS
cord-313312-h607itv2	201	31	.	.	.
cord-313312-h607itv2	202	1	In	in	IN
cord-313312-h607itv2	202	2	addition	addition	NN
cord-313312-h607itv2	202	3	,	,	,
cord-313312-h607itv2	202	4	the	the	DT
cord-313312-h607itv2	202	5	cross	cross	NN
cord-313312-h607itv2	202	6	-	-	NN
cord-313312-h607itv2	202	7	linking	linking	NN
cord-313312-h607itv2	202	8	of	of	IN
cord-313312-h607itv2	202	9	FcγRs	FcγRs	NNP
cord-313312-h607itv2	202	10	causes	cause	NNS
cord-313312-h607itv2	202	11	increased	increase	VBN
cord-313312-h607itv2	202	12	expression	expression	NN
cord-313312-h607itv2	202	13	of	of	IN
cord-313312-h607itv2	202	14	immune	immune	JJ
cord-313312-h607itv2	202	15	semaphorins	semaphorin	NNS
cord-313312-h607itv2	202	16	,	,	,
cord-313312-h607itv2	202	17	which	which	WDT
cord-313312-h607itv2	202	18	are	be	VBP
cord-313312-h607itv2	202	19	critical	critical	JJ
cord-313312-h607itv2	202	20	for	for	IN
cord-313312-h607itv2	202	21	antigen	antigen	NN
cord-313312-h607itv2	202	22	-	-	HYPH
cord-313312-h607itv2	202	23	presenting	present	VBG
cord-313312-h607itv2	202	24	cell	cell	NN
cord-313312-h607itv2	202	25	and	and	CC
cord-313312-h607itv2	202	26	T	t	NN
cord-313312-h607itv2	202	27	-	-	HYPH
cord-313312-h607itv2	202	28	cell	cell	NN
cord-313312-h607itv2	202	29	interaction	interaction	NN
cord-313312-h607itv2	202	30	.	.	.
cord-313312-h607itv2	203	1	Overall	overall	RB
cord-313312-h607itv2	203	2	,	,	,
cord-313312-h607itv2	203	3	this	this	DT
cord-313312-h607itv2	203	4	leads	lead	VBZ
cord-313312-h607itv2	203	5	to	to	IN
cord-313312-h607itv2	203	6	increased	increase	VBN
cord-313312-h607itv2	203	7	T	t	NN
cord-313312-h607itv2	203	8	-	-	HYPH
cord-313312-h607itv2	203	9	cell	cell	NN
cord-313312-h607itv2	203	10	proliferation	proliferation	NN
cord-313312-h607itv2	203	11	and	and	CC
cord-313312-h607itv2	203	12	activation	activation	NN
cord-313312-h607itv2	203	13	,	,	,
cord-313312-h607itv2	203	14	which	which	WDT
cord-313312-h607itv2	203	15	consequently	consequently	RB
cord-313312-h607itv2	203	16	improves	improve	VBZ
cord-313312-h607itv2	203	17	LAV	LAV	NNP
cord-313312-h607itv2	203	18	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	203	19	.	.	.
cord-313312-h607itv2	204	1	In	in	IN
cord-313312-h607itv2	204	2	this	this	DT
cord-313312-h607itv2	204	3	review	review	NN
cord-313312-h607itv2	204	4	,	,	,
cord-313312-h607itv2	204	5	we	-PRON-	PRP
cord-313312-h607itv2	204	6	have	have	VBP
cord-313312-h607itv2	204	7	highlighted	highlight	VBN
cord-313312-h607itv2	204	8	several	several	JJ
cord-313312-h607itv2	204	9	studies	study	NNS
cord-313312-h607itv2	204	10	that	that	WDT
cord-313312-h607itv2	204	11	have	have	VBP
cord-313312-h607itv2	204	12	shown	show	VBN
cord-313312-h607itv2	204	13	that	that	IN
cord-313312-h607itv2	204	14	the	the	DT
cord-313312-h607itv2	204	15	efficacy	efficacy	NN
cord-313312-h607itv2	204	16	of	of	IN
cord-313312-h607itv2	204	17	some	some	DT
cord-313312-h607itv2	204	18	commonly	commonly	RB
cord-313312-h607itv2	204	19	used	use	VBN
cord-313312-h607itv2	204	20	LAVs	lav	NNS
cord-313312-h607itv2	204	21	,	,	,
cord-313312-h607itv2	204	22	such	such	JJ
cord-313312-h607itv2	204	23	as	as	IN
cord-313312-h607itv2	204	24	measles	measles	NN
cord-313312-h607itv2	204	25	,	,	,
cord-313312-h607itv2	204	26	adenovirus	adenovirus	NN
cord-313312-h607itv2	204	27	,	,	,
cord-313312-h607itv2	204	28	influenza	influenza	NN
cord-313312-h607itv2	204	29	,	,	,
cord-313312-h607itv2	204	30	and	and	CC
cord-313312-h607itv2	204	31	flaviviral	flaviviral	JJ
cord-313312-h607itv2	204	32	vaccines	vaccine	NNS
cord-313312-h607itv2	204	33	,	,	,
cord-313312-h607itv2	204	34	can	can	MD
cord-313312-h607itv2	204	35	be	be	VB
cord-313312-h607itv2	204	36	affected	affect	VBN
cord-313312-h607itv2	204	37	by	by	IN
cord-313312-h607itv2	204	38	these	these	DT
cord-313312-h607itv2	204	39	pre	pre	JJ
cord-313312-h607itv2	204	40	-	-	JJ
cord-313312-h607itv2	204	41	existing	existing	JJ
cord-313312-h607itv2	204	42	adaptive	adaptive	JJ
cord-313312-h607itv2	204	43	immune	immune	JJ
cord-313312-h607itv2	204	44	responses	response	NNS
cord-313312-h607itv2	204	45	.	.	.
cord-313312-h607itv2	205	1	This	this	DT
cord-313312-h607itv2	205	2	knowledge	knowledge	NN
cord-313312-h607itv2	205	3	will	will	MD
cord-313312-h607itv2	205	4	be	be	VB
cord-313312-h607itv2	205	5	critical	critical	JJ
cord-313312-h607itv2	205	6	to	to	IN
cord-313312-h607itv2	205	7	understanding	understand	VBG
cord-313312-h607itv2	205	8	the	the	DT
cord-313312-h607itv2	205	9	limitations	limitation	NNS
cord-313312-h607itv2	205	10	of	of	IN
cord-313312-h607itv2	205	11	administering	administer	VBG
cord-313312-h607itv2	205	12	LAVs	lav	NNS
cord-313312-h607itv2	205	13	in	in	IN
cord-313312-h607itv2	205	14	seropositive	seropositive	JJ
cord-313312-h607itv2	205	15	individuals	individual	NNS
cord-313312-h607itv2	205	16	to	to	TO
cord-313312-h607itv2	205	17	reduce	reduce	VB
cord-313312-h607itv2	205	18	the	the	DT
cord-313312-h607itv2	205	19	incidence	incidence	NN
cord-313312-h607itv2	205	20	of	of	IN
cord-313312-h607itv2	205	21	vaccine	vaccine	NN
cord-313312-h607itv2	205	22	failures	failure	NNS
cord-313312-h607itv2	205	23	,	,	,
cord-313312-h607itv2	205	24	as	as	RB
cord-313312-h607itv2	205	25	well	well	RB
cord-313312-h607itv2	205	26	as	as	IN
cord-313312-h607itv2	205	27	in	in	IN
cord-313312-h607itv2	205	28	future	future	JJ
cord-313312-h607itv2	205	29	designs	design	NNS
cord-313312-h607itv2	205	30	of	of	IN
cord-313312-h607itv2	205	31	clinical	clinical	JJ
cord-313312-h607itv2	205	32	trials	trial	NNS
cord-313312-h607itv2	205	33	to	to	TO
cord-313312-h607itv2	205	34	evaluate	evaluate	VB
cord-313312-h607itv2	205	35	the	the	DT
cord-313312-h607itv2	205	36	efficacy	efficacy	NN
cord-313312-h607itv2	205	37	of	of	IN
cord-313312-h607itv2	205	38	LAVs	lav	NNS
cord-313312-h607itv2	205	39	.	.	.
cord-313312-h607itv2	206	1	Whether	whether	IN
cord-313312-h607itv2	206	2	preexisting	preexisting	JJ
cord-313312-h607itv2	206	3	antibodies	antibody	NNS
cord-313312-h607itv2	206	4	can	can	MD
cord-313312-h607itv2	206	5	inhibit	inhibit	VB
cord-313312-h607itv2	206	6	or	or	CC
cord-313312-h607itv2	206	7	augment	augment	VB
cord-313312-h607itv2	206	8	LAV	LAV	NNP
cord-313312-h607itv2	206	9	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	206	10	depends	depend	VBZ
cord-313312-h607itv2	206	11	on	on	IN
cord-313312-h607itv2	206	12	the	the	DT
cord-313312-h607itv2	206	13	concentration	concentration	NN
cord-313312-h607itv2	206	14	and	and	CC
cord-313312-h607itv2	206	15	the	the	DT
cord-313312-h607itv2	206	16	type	type	NN
cord-313312-h607itv2	206	17	of	of	IN
cord-313312-h607itv2	206	18	antibodies	antibody	NNS
cord-313312-h607itv2	206	19	that	that	WDT
cord-313312-h607itv2	206	20	are	be	VBP
cord-313312-h607itv2	206	21	present	present	JJ
cord-313312-h607itv2	207	1	(	(	-LRB-
cord-313312-h607itv2	207	2	Figure	figure	NN
cord-313312-h607itv2	207	3	4	4	CD
cord-313312-h607itv2	207	4	)	)	-RRB-
cord-313312-h607itv2	207	5	.	.	.
cord-313312-h607itv2	208	1	With	with	IN
cord-313312-h607itv2	208	2	high	high	JJ
cord-313312-h607itv2	208	3	antibody	antibody	NN
cord-313312-h607itv2	208	4	levels	level	NNS
cord-313312-h607itv2	208	5	or	or	CC
cord-313312-h607itv2	208	6	potently	potently	RB
cord-313312-h607itv2	208	7	neutralizing	neutralize	VBG
cord-313312-h607itv2	208	8	antibodies	antibody	NNS
cord-313312-h607itv2	208	9	,	,	,
cord-313312-h607itv2	208	10	pre	pre	JJ
cord-313312-h607itv2	208	11	-	-	JJ
cord-313312-h607itv2	208	12	existing	existing	JJ
cord-313312-h607itv2	208	13	antibodies	antibody	NNS
cord-313312-h607itv2	208	14	can	can	MD
cord-313312-h607itv2	208	15	inhibit	inhibit	VB
cord-313312-h607itv2	208	16	LAV	LAV	NNP
cord-313312-h607itv2	208	17	efficacy	efficacy	NN
cord-313312-h607itv2	208	18	by	by	IN
cord-313312-h607itv2	208	19	virus	virus	NN
cord-313312-h607itv2	208	20	neutralization	neutralization	NN
cord-313312-h607itv2	208	21	or	or	CC
cord-313312-h607itv2	208	22	inhibition	inhibition	NN
cord-313312-h607itv2	208	23	of	of	IN
cord-313312-h607itv2	208	24	Bcell	Bcell	NNP
cord-313312-h607itv2	208	25	responses	response	NNS
cord-313312-h607itv2	208	26	.	.	.
cord-313312-h607itv2	209	1	By	by	IN
cord-313312-h607itv2	209	2	contrast	contrast	NN
cord-313312-h607itv2	209	3	,	,	,
cord-313312-h607itv2	209	4	at	at	IN
cord-313312-h607itv2	209	5	sub	sub	NN
cord-313312-h607itv2	209	6	-	-	JJ
cord-313312-h607itv2	209	7	neutralizing	neutralize	VBG
cord-313312-h607itv2	209	8	titers	titer	NNS
cord-313312-h607itv2	209	9	,	,	,
cord-313312-h607itv2	209	10	pre	pre	JJ
cord-313312-h607itv2	209	11	-	-	JJ
cord-313312-h607itv2	209	12	existing	existing	JJ
cord-313312-h607itv2	209	13	antibodies	antibody	NNS
cord-313312-h607itv2	209	14	can	can	MD
cord-313312-h607itv2	209	15	enable	enable	VB
cord-313312-h607itv2	209	16	viruses	virus	NNS
cord-313312-h607itv2	209	17	to	to	TO
cord-313312-h607itv2	209	18	better	well	RBR
cord-313312-h607itv2	209	19	infect	infect	VB
cord-313312-h607itv2	209	20	cells	cell	NNS
cord-313312-h607itv2	209	21	and	and	CC
cord-313312-h607itv2	209	22	increase	increase	VB
cord-313312-h607itv2	209	23	innate	innate	JJ
cord-313312-h607itv2	209	24	immune	immune	JJ
cord-313312-h607itv2	209	25	responses	response	NNS
cord-313312-h607itv2	209	26	that	that	WDT
cord-313312-h607itv2	209	27	augment	augment	VBP
cord-313312-h607itv2	209	28	LAV	LAV	NNP
cord-313312-h607itv2	209	29	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	209	30	.	.	.
cord-313312-h607itv2	210	1	Moreover	moreover	RB
cord-313312-h607itv2	210	2	,	,	,
cord-313312-h607itv2	210	3	pre	pre	JJ
cord-313312-h607itv2	210	4	-	-	JJ
cord-313312-h607itv2	210	5	existing	existing	JJ
cord-313312-h607itv2	210	6	immunity	immunity	NN
cord-313312-h607itv2	210	7	can	can	MD
cord-313312-h607itv2	210	8	prime	prime	JJ
cord-313312-h607itv2	210	9	dendritic	dendritic	JJ
cord-313312-h607itv2	210	10	cells	cell	NNS
cord-313312-h607itv2	210	11	and	and	CC
cord-313312-h607itv2	210	12	memory	memory	NN
cord-313312-h607itv2	210	13	T	t	NN
cord-313312-h607itv2	210	14	-	-	HYPH
cord-313312-h607itv2	210	15	cells	cell	NNS
cord-313312-h607itv2	210	16	to	to	TO
cord-313312-h607itv2	210	17	enhance	enhance	VB
cord-313312-h607itv2	210	18	protection	protection	NN
cord-313312-h607itv2	210	19	during	during	IN
cord-313312-h607itv2	210	20	secondary	secondary	JJ
cord-313312-h607itv2	210	21	infection	infection	NN
cord-313312-h607itv2	210	22	with	with	IN
cord-313312-h607itv2	210	23	an	an	DT
cord-313312-h607itv2	210	24	antigenically	antigenically	RB
cord-313312-h607itv2	210	25	related	relate	VBN
cord-313312-h607itv2	210	26	virus	virus	NN
cord-313312-h607itv2	210	27	[	[	-LRB-
cord-313312-h607itv2	210	28	83	83	CD
cord-313312-h607itv2	210	29	]	]	-RRB-
cord-313312-h607itv2	210	30	.	.	.
cord-313312-h607itv2	211	1	We	-PRON-	PRP
cord-313312-h607itv2	211	2	believe	believe	VBP
cord-313312-h607itv2	211	3	that	that	IN
cord-313312-h607itv2	211	4	a	a	DT
cord-313312-h607itv2	211	5	deeper	deep	JJR
cord-313312-h607itv2	211	6	understanding	understanding	NN
cord-313312-h607itv2	211	7	of	of	IN
cord-313312-h607itv2	211	8	the	the	DT
cord-313312-h607itv2	211	9	underlying	underlie	VBG
cord-313312-h607itv2	211	10	mechanisms	mechanism	NNS
cord-313312-h607itv2	211	11	involved	involve	VBN
cord-313312-h607itv2	211	12	will	will	MD
cord-313312-h607itv2	211	13	help	help	VB
cord-313312-h607itv2	211	14	us	-PRON-	PRP
cord-313312-h607itv2	211	15	better	well	RBR
cord-313312-h607itv2	211	16	understand	understand	VB
cord-313312-h607itv2	211	17	the	the	DT
cord-313312-h607itv2	211	18	circumstances	circumstance	NNS
cord-313312-h607itv2	211	19	that	that	WDT
cord-313312-h607itv2	211	20	can	can	MD
cord-313312-h607itv2	211	21	allow	allow	VB
cord-313312-h607itv2	211	22	us	-PRON-	PRP
cord-313312-h607itv2	211	23	to	to	TO
cord-313312-h607itv2	211	24	manage	manage	VB
cord-313312-h607itv2	211	25	immunization	immunization	NN
cord-313312-h607itv2	211	26	in	in	IN
cord-313312-h607itv2	211	27	the	the	DT
cord-313312-h607itv2	211	28	presence	presence	NN
cord-313312-h607itv2	211	29	of	of	IN
cord-313312-h607itv2	211	30	pre	pre	JJ
cord-313312-h607itv2	211	31	-	-	JJ
cord-313312-h607itv2	211	32	existing	existing	JJ
cord-313312-h607itv2	211	33	antibodies	antibody	NNS
cord-313312-h607itv2	211	34	,	,	,
cord-313312-h607itv2	211	35	and	and	CC
cord-313312-h607itv2	211	36	even	even	RB
cord-313312-h607itv2	211	37	explore	explore	VB
cord-313312-h607itv2	211	38	the	the	DT
cord-313312-h607itv2	211	39	possibilities	possibility	NNS
cord-313312-h607itv2	211	40	of	of	IN
cord-313312-h607itv2	211	41	exploiting	exploit	VBG
cord-313312-h607itv2	211	42	pre	pre	JJ
cord-313312-h607itv2	211	43	-	-	JJ
cord-313312-h607itv2	211	44	existing	existing	JJ
cord-313312-h607itv2	211	45	antibodies	antibody	NNS
cord-313312-h607itv2	211	46	to	to	TO
cord-313312-h607itv2	211	47	promote	promote	VB
cord-313312-h607itv2	211	48	vaccine	vaccine	NN
cord-313312-h607itv2	211	49	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	211	50	and	and	CC
cord-313312-h607itv2	211	51	efficacy	efficacy	NN
cord-313312-h607itv2	211	52	.	.	.
cord-313312-h607itv2	212	1	It	-PRON-	PRP
cord-313312-h607itv2	212	2	would	would	MD
cord-313312-h607itv2	212	3	also	also	RB
cord-313312-h607itv2	212	4	be	be	VB
cord-313312-h607itv2	212	5	interesting	interesting	JJ
cord-313312-h607itv2	212	6	to	to	TO
cord-313312-h607itv2	212	7	determine	determine	VB
cord-313312-h607itv2	212	8	if	if	IN
cord-313312-h607itv2	212	9	cross	cross	JJ
cord-313312-h607itv2	212	10	-	-	JJ
cord-313312-h607itv2	212	11	reactive	reactive	JJ
cord-313312-h607itv2	212	12	antibodies	antibody	NNS
cord-313312-h607itv2	212	13	Immune	Immune	NNP
cord-313312-h607itv2	212	14	complexes	complex	NNS
cord-313312-h607itv2	212	15	formed	form	VBN
cord-313312-h607itv2	212	16	by	by	IN
cord-313312-h607itv2	212	17	pre	pre	JJ
cord-313312-h607itv2	212	18	-	-	JJ
cord-313312-h607itv2	212	19	existing	existing	JJ
cord-313312-h607itv2	212	20	antibodies	antibody	NNS
cord-313312-h607itv2	212	21	and	and	CC
cord-313312-h607itv2	212	22	viruses	virus	NNS
cord-313312-h607itv2	212	23	can	can	MD
cord-313312-h607itv2	212	24	engage	engage	VB
cord-313312-h607itv2	212	25	FcγRs	FcγRs	NNP
cord-313312-h607itv2	212	26	,	,	,
cord-313312-h607itv2	212	27	resulting	result	VBG
cord-313312-h607itv2	212	28	in	in	IN
cord-313312-h607itv2	212	29	increased	increase	VBN
cord-313312-h607itv2	212	30	viral	viral	JJ
cord-313312-h607itv2	212	31	uptake	uptake	NN
cord-313312-h607itv2	212	32	and	and	CC
cord-313312-h607itv2	212	33	fusion	fusion	NN
cord-313312-h607itv2	212	34	through	through	IN
cord-313312-h607itv2	212	35	the	the	DT
cord-313312-h607itv2	212	36	process	process	NN
cord-313312-h607itv2	212	37	of	of	IN
cord-313312-h607itv2	212	38	antibody	antibody	NN
cord-313312-h607itv2	212	39	-	-	HYPH
cord-313312-h607itv2	212	40	dependent	dependent	JJ
cord-313312-h607itv2	212	41	enhancement	enhancement	NN
cord-313312-h607itv2	212	42	that	that	WDT
cord-313312-h607itv2	212	43	leads	lead	VBZ
cord-313312-h607itv2	212	44	to	to	IN
cord-313312-h607itv2	212	45	increased	increase	VBN
cord-313312-h607itv2	212	46	vaccine	vaccine	NN
cord-313312-h607itv2	212	47	viremia	viremia	NN
cord-313312-h607itv2	212	48	and	and	CC
cord-313312-h607itv2	212	49	antigen	antigen	NN
cord-313312-h607itv2	212	50	presentation	presentation	NN
cord-313312-h607itv2	212	51	.	.	.
cord-313312-h607itv2	213	1	Activating	activate	VBG
cord-313312-h607itv2	213	2	FcγR	fcγr	NN
cord-313312-h607itv2	213	3	-	-	HYPH
cord-313312-h607itv2	213	4	signaling	signal	VBG
cord-313312-h607itv2	213	5	,	,	,
cord-313312-h607itv2	213	6	on	on	IN
cord-313312-h607itv2	213	7	the	the	DT
cord-313312-h607itv2	213	8	other	other	JJ
cord-313312-h607itv2	213	9	hand	hand	NN
cord-313312-h607itv2	213	10	,	,	,
cord-313312-h607itv2	213	11	provokes	provoke	VBZ
cord-313312-h607itv2	213	12	greater	great	JJR
cord-313312-h607itv2	213	13	innate	innate	JJ
cord-313312-h607itv2	213	14	immune	immune	JJ
cord-313312-h607itv2	213	15	responses	response	NNS
cord-313312-h607itv2	213	16	and	and	CC
cord-313312-h607itv2	213	17	production	production	NN
cord-313312-h607itv2	213	18	of	of	IN
cord-313312-h607itv2	213	19	pro	pro	JJ
cord-313312-h607itv2	213	20	-	-	JJ
cord-313312-h607itv2	213	21	inflammatory	inflammatory	JJ
cord-313312-h607itv2	213	22	metabolites	metabolite	NNS
cord-313312-h607itv2	213	23	that	that	WDT
cord-313312-h607itv2	213	24	can	can	MD
cord-313312-h607itv2	213	25	enhance	enhance	VB
cord-313312-h607itv2	213	26	innate	innate	JJ
cord-313312-h607itv2	213	27	and	and	CC
cord-313312-h607itv2	213	28	adaptive	adaptive	JJ
cord-313312-h607itv2	213	29	immune	immune	JJ
cord-313312-h607itv2	213	30	responses	response	NNS
cord-313312-h607itv2	213	31	.	.	.
cord-313312-h607itv2	214	1	In	in	IN
cord-313312-h607itv2	214	2	addition	addition	NN
cord-313312-h607itv2	214	3	,	,	,
cord-313312-h607itv2	214	4	the	the	DT
cord-313312-h607itv2	214	5	cross	cross	NN
cord-313312-h607itv2	214	6	-	-	NN
cord-313312-h607itv2	214	7	linking	linking	NN
cord-313312-h607itv2	214	8	of	of	IN
cord-313312-h607itv2	214	9	FcγRs	FcγRs	NNP
cord-313312-h607itv2	214	10	causes	cause	NNS
cord-313312-h607itv2	214	11	increased	increase	VBN
cord-313312-h607itv2	214	12	expression	expression	NN
cord-313312-h607itv2	214	13	of	of	IN
cord-313312-h607itv2	214	14	immune	immune	JJ
cord-313312-h607itv2	214	15	semaphorins	semaphorin	NNS
cord-313312-h607itv2	214	16	,	,	,
cord-313312-h607itv2	214	17	which	which	WDT
cord-313312-h607itv2	214	18	are	be	VBP
cord-313312-h607itv2	214	19	critical	critical	JJ
cord-313312-h607itv2	214	20	for	for	IN
cord-313312-h607itv2	214	21	antigen	antigen	NN
cord-313312-h607itv2	214	22	-	-	HYPH
cord-313312-h607itv2	214	23	presenting	present	VBG
cord-313312-h607itv2	214	24	cell	cell	NN
cord-313312-h607itv2	214	25	and	and	CC
cord-313312-h607itv2	214	26	T	t	NN
cord-313312-h607itv2	214	27	-	-	HYPH
cord-313312-h607itv2	214	28	cell	cell	NN
cord-313312-h607itv2	214	29	interaction	interaction	NN
cord-313312-h607itv2	214	30	.	.	.
cord-313312-h607itv2	215	1	Overall	overall	RB
cord-313312-h607itv2	215	2	,	,	,
cord-313312-h607itv2	215	3	this	this	DT
cord-313312-h607itv2	215	4	leads	lead	VBZ
cord-313312-h607itv2	215	5	to	to	IN
cord-313312-h607itv2	215	6	increased	increase	VBN
cord-313312-h607itv2	215	7	T	t	NN
cord-313312-h607itv2	215	8	-	-	HYPH
cord-313312-h607itv2	215	9	cell	cell	NN
cord-313312-h607itv2	215	10	proliferation	proliferation	NN
cord-313312-h607itv2	215	11	and	and	CC
cord-313312-h607itv2	215	12	activation	activation	NN
cord-313312-h607itv2	215	13	,	,	,
cord-313312-h607itv2	215	14	which	which	WDT
cord-313312-h607itv2	215	15	consequently	consequently	RB
cord-313312-h607itv2	215	16	improves	improve	VBZ
cord-313312-h607itv2	215	17	LAV	LAV	NNP
cord-313312-h607itv2	215	18	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	215	19	.	.	.
cord-313312-h607itv2	216	1	In	in	IN
cord-313312-h607itv2	216	2	this	this	DT
cord-313312-h607itv2	216	3	review	review	NN
cord-313312-h607itv2	216	4	,	,	,
cord-313312-h607itv2	216	5	we	-PRON-	PRP
cord-313312-h607itv2	216	6	have	have	VBP
cord-313312-h607itv2	216	7	highlighted	highlight	VBN
cord-313312-h607itv2	216	8	several	several	JJ
cord-313312-h607itv2	216	9	studies	study	NNS
cord-313312-h607itv2	216	10	that	that	WDT
cord-313312-h607itv2	216	11	have	have	VBP
cord-313312-h607itv2	216	12	shown	show	VBN
cord-313312-h607itv2	216	13	that	that	IN
cord-313312-h607itv2	216	14	the	the	DT
cord-313312-h607itv2	216	15	efficacy	efficacy	NN
cord-313312-h607itv2	216	16	of	of	IN
cord-313312-h607itv2	216	17	some	some	DT
cord-313312-h607itv2	216	18	commonly	commonly	RB
cord-313312-h607itv2	216	19	used	use	VBN
cord-313312-h607itv2	216	20	LAVs	lav	NNS
cord-313312-h607itv2	216	21	,	,	,
cord-313312-h607itv2	216	22	such	such	JJ
cord-313312-h607itv2	216	23	as	as	IN
cord-313312-h607itv2	216	24	measles	measles	NN
cord-313312-h607itv2	216	25	,	,	,
cord-313312-h607itv2	216	26	adenovirus	adenovirus	NN
cord-313312-h607itv2	216	27	,	,	,
cord-313312-h607itv2	216	28	influenza	influenza	NN
cord-313312-h607itv2	216	29	,	,	,
cord-313312-h607itv2	216	30	and	and	CC
cord-313312-h607itv2	216	31	flaviviral	flaviviral	JJ
cord-313312-h607itv2	216	32	vaccines	vaccine	NNS
cord-313312-h607itv2	216	33	,	,	,
cord-313312-h607itv2	216	34	can	can	MD
cord-313312-h607itv2	216	35	be	be	VB
cord-313312-h607itv2	216	36	affected	affect	VBN
cord-313312-h607itv2	216	37	by	by	IN
cord-313312-h607itv2	216	38	these	these	DT
cord-313312-h607itv2	216	39	pre	pre	JJ
cord-313312-h607itv2	216	40	-	-	JJ
cord-313312-h607itv2	216	41	existing	existing	JJ
cord-313312-h607itv2	216	42	adaptive	adaptive	JJ
cord-313312-h607itv2	216	43	immune	immune	JJ
cord-313312-h607itv2	216	44	responses	response	NNS
cord-313312-h607itv2	216	45	.	.	.
cord-313312-h607itv2	217	1	This	this	DT
cord-313312-h607itv2	217	2	knowledge	knowledge	NN
cord-313312-h607itv2	217	3	will	will	MD
cord-313312-h607itv2	217	4	be	be	VB
cord-313312-h607itv2	217	5	critical	critical	JJ
cord-313312-h607itv2	217	6	to	to	IN
cord-313312-h607itv2	217	7	understanding	understand	VBG
cord-313312-h607itv2	217	8	the	the	DT
cord-313312-h607itv2	217	9	limitations	limitation	NNS
cord-313312-h607itv2	217	10	of	of	IN
cord-313312-h607itv2	217	11	administering	administer	VBG
cord-313312-h607itv2	217	12	LAVs	lav	NNS
cord-313312-h607itv2	217	13	in	in	IN
cord-313312-h607itv2	217	14	seropositive	seropositive	JJ
cord-313312-h607itv2	217	15	individuals	individual	NNS
cord-313312-h607itv2	217	16	to	to	TO
cord-313312-h607itv2	217	17	reduce	reduce	VB
cord-313312-h607itv2	217	18	the	the	DT
cord-313312-h607itv2	217	19	incidence	incidence	NN
cord-313312-h607itv2	217	20	of	of	IN
cord-313312-h607itv2	217	21	vaccine	vaccine	NN
cord-313312-h607itv2	217	22	failures	failure	NNS
cord-313312-h607itv2	217	23	,	,	,
cord-313312-h607itv2	217	24	as	as	RB
cord-313312-h607itv2	217	25	well	well	RB
cord-313312-h607itv2	217	26	as	as	IN
cord-313312-h607itv2	217	27	in	in	IN
cord-313312-h607itv2	217	28	future	future	JJ
cord-313312-h607itv2	217	29	designs	design	NNS
cord-313312-h607itv2	217	30	of	of	IN
cord-313312-h607itv2	217	31	clinical	clinical	JJ
cord-313312-h607itv2	217	32	trials	trial	NNS
cord-313312-h607itv2	217	33	to	to	TO
cord-313312-h607itv2	217	34	evaluate	evaluate	VB
cord-313312-h607itv2	217	35	the	the	DT
cord-313312-h607itv2	217	36	efficacy	efficacy	NN
cord-313312-h607itv2	217	37	of	of	IN
cord-313312-h607itv2	217	38	LAVs	lav	NNS
cord-313312-h607itv2	217	39	.	.	.
cord-313312-h607itv2	218	1	Whether	whether	IN
cord-313312-h607itv2	218	2	pre	pre	JJ
cord-313312-h607itv2	218	3	-	-	JJ
cord-313312-h607itv2	218	4	existing	existing	JJ
cord-313312-h607itv2	218	5	antibodies	antibody	NNS
cord-313312-h607itv2	218	6	can	can	MD
cord-313312-h607itv2	218	7	inhibit	inhibit	VB
cord-313312-h607itv2	218	8	or	or	CC
cord-313312-h607itv2	218	9	augment	augment	VB
cord-313312-h607itv2	218	10	LAV	LAV	NNP
cord-313312-h607itv2	218	11	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	218	12	depends	depend	VBZ
cord-313312-h607itv2	218	13	on	on	IN
cord-313312-h607itv2	218	14	the	the	DT
cord-313312-h607itv2	218	15	concentration	concentration	NN
cord-313312-h607itv2	218	16	and	and	CC
cord-313312-h607itv2	218	17	the	the	DT
cord-313312-h607itv2	218	18	type	type	NN
cord-313312-h607itv2	218	19	of	of	IN
cord-313312-h607itv2	218	20	antibodies	antibody	NNS
cord-313312-h607itv2	218	21	that	that	WDT
cord-313312-h607itv2	218	22	are	be	VBP
cord-313312-h607itv2	218	23	present	present	JJ
cord-313312-h607itv2	219	1	(	(	-LRB-
cord-313312-h607itv2	219	2	Figure	figure	NN
cord-313312-h607itv2	219	3	4	4	CD
cord-313312-h607itv2	219	4	)	)	-RRB-
cord-313312-h607itv2	219	5	.	.	.
cord-313312-h607itv2	220	1	With	with	IN
cord-313312-h607itv2	220	2	high	high	JJ
cord-313312-h607itv2	220	3	antibody	antibody	NN
cord-313312-h607itv2	220	4	levels	level	NNS
cord-313312-h607itv2	220	5	or	or	CC
cord-313312-h607itv2	220	6	potently	potently	RB
cord-313312-h607itv2	220	7	neutralizing	neutralize	VBG
cord-313312-h607itv2	220	8	antibodies	antibody	NNS
cord-313312-h607itv2	220	9	,	,	,
cord-313312-h607itv2	220	10	pre	pre	JJ
cord-313312-h607itv2	220	11	-	-	JJ
cord-313312-h607itv2	220	12	existing	existing	JJ
cord-313312-h607itv2	220	13	antibodies	antibody	NNS
cord-313312-h607itv2	220	14	can	can	MD
cord-313312-h607itv2	220	15	inhibit	inhibit	VB
cord-313312-h607itv2	220	16	LAV	LAV	NNP
cord-313312-h607itv2	220	17	efficacy	efficacy	NN
cord-313312-h607itv2	220	18	by	by	IN
cord-313312-h607itv2	220	19	virus	virus	NN
cord-313312-h607itv2	220	20	neutralization	neutralization	NN
cord-313312-h607itv2	220	21	or	or	CC
cord-313312-h607itv2	220	22	inhibition	inhibition	NN
cord-313312-h607itv2	220	23	of	of	IN
cord-313312-h607itv2	220	24	B	b	NN
cord-313312-h607itv2	220	25	-	-	HYPH
cord-313312-h607itv2	220	26	cell	cell	NN
cord-313312-h607itv2	220	27	responses	response	NNS
cord-313312-h607itv2	220	28	.	.	.
cord-313312-h607itv2	221	1	By	by	IN
cord-313312-h607itv2	221	2	contrast	contrast	NN
cord-313312-h607itv2	221	3	,	,	,
cord-313312-h607itv2	221	4	at	at	IN
cord-313312-h607itv2	221	5	sub	sub	NN
cord-313312-h607itv2	221	6	-	-	JJ
cord-313312-h607itv2	221	7	neutralizing	neutralize	VBG
cord-313312-h607itv2	221	8	titers	titer	NNS
cord-313312-h607itv2	221	9	,	,	,
cord-313312-h607itv2	221	10	pre	pre	JJ
cord-313312-h607itv2	221	11	-	-	JJ
cord-313312-h607itv2	221	12	existing	existing	JJ
cord-313312-h607itv2	221	13	antibodies	antibody	NNS
cord-313312-h607itv2	221	14	can	can	MD
cord-313312-h607itv2	221	15	enable	enable	VB
cord-313312-h607itv2	221	16	viruses	virus	NNS
cord-313312-h607itv2	221	17	to	to	TO
cord-313312-h607itv2	221	18	better	well	RBR
cord-313312-h607itv2	221	19	infect	infect	VB
cord-313312-h607itv2	221	20	cells	cell	NNS
cord-313312-h607itv2	221	21	and	and	CC
cord-313312-h607itv2	221	22	increase	increase	VB
cord-313312-h607itv2	221	23	innate	innate	JJ
cord-313312-h607itv2	221	24	immune	immune	JJ
cord-313312-h607itv2	221	25	responses	response	NNS
cord-313312-h607itv2	221	26	that	that	WDT
cord-313312-h607itv2	221	27	augment	augment	VBP
cord-313312-h607itv2	221	28	LAV	LAV	NNP
cord-313312-h607itv2	221	29	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	221	30	.	.	.
cord-313312-h607itv2	222	1	Moreover	moreover	RB
cord-313312-h607itv2	222	2	,	,	,
cord-313312-h607itv2	222	3	pre	pre	JJ
cord-313312-h607itv2	222	4	-	-	JJ
cord-313312-h607itv2	222	5	existing	existing	JJ
cord-313312-h607itv2	222	6	immunity	immunity	NN
cord-313312-h607itv2	222	7	can	can	MD
cord-313312-h607itv2	222	8	prime	prime	JJ
cord-313312-h607itv2	222	9	dendritic	dendritic	JJ
cord-313312-h607itv2	222	10	cells	cell	NNS
cord-313312-h607itv2	222	11	and	and	CC
cord-313312-h607itv2	222	12	memory	memory	NN
cord-313312-h607itv2	222	13	T	t	NN
cord-313312-h607itv2	222	14	-	-	HYPH
cord-313312-h607itv2	222	15	cells	cell	NNS
cord-313312-h607itv2	222	16	to	to	TO
cord-313312-h607itv2	222	17	enhance	enhance	VB
cord-313312-h607itv2	222	18	protection	protection	NN
cord-313312-h607itv2	222	19	during	during	IN
cord-313312-h607itv2	222	20	secondary	secondary	JJ
cord-313312-h607itv2	222	21	infection	infection	NN
cord-313312-h607itv2	222	22	with	with	IN
cord-313312-h607itv2	222	23	an	an	DT
cord-313312-h607itv2	222	24	antigenically	antigenically	RB
cord-313312-h607itv2	222	25	related	relate	VBN
cord-313312-h607itv2	222	26	virus	virus	NN
cord-313312-h607itv2	222	27	[	[	-LRB-
cord-313312-h607itv2	222	28	83	83	CD
cord-313312-h607itv2	222	29	]	]	-RRB-
cord-313312-h607itv2	222	30	.	.	.
cord-313312-h607itv2	223	1	We	-PRON-	PRP
cord-313312-h607itv2	223	2	believe	believe	VBP
cord-313312-h607itv2	223	3	that	that	IN
cord-313312-h607itv2	223	4	a	a	DT
cord-313312-h607itv2	223	5	deeper	deep	JJR
cord-313312-h607itv2	223	6	understanding	understanding	NN
cord-313312-h607itv2	223	7	of	of	IN
cord-313312-h607itv2	223	8	the	the	DT
cord-313312-h607itv2	223	9	underlying	underlie	VBG
cord-313312-h607itv2	223	10	mechanisms	mechanism	NNS
cord-313312-h607itv2	223	11	involved	involve	VBN
cord-313312-h607itv2	223	12	will	will	MD
cord-313312-h607itv2	223	13	help	help	VB
cord-313312-h607itv2	223	14	us	-PRON-	PRP
cord-313312-h607itv2	223	15	better	well	RBR
cord-313312-h607itv2	223	16	understand	understand	VB
cord-313312-h607itv2	223	17	the	the	DT
cord-313312-h607itv2	223	18	circumstances	circumstance	NNS
cord-313312-h607itv2	223	19	that	that	WDT
cord-313312-h607itv2	223	20	can	can	MD
cord-313312-h607itv2	223	21	allow	allow	VB
cord-313312-h607itv2	223	22	us	-PRON-	PRP
cord-313312-h607itv2	223	23	to	to	TO
cord-313312-h607itv2	223	24	manage	manage	VB
cord-313312-h607itv2	223	25	immunization	immunization	NN
cord-313312-h607itv2	223	26	in	in	IN
cord-313312-h607itv2	223	27	the	the	DT
cord-313312-h607itv2	223	28	presence	presence	NN
cord-313312-h607itv2	223	29	of	of	IN
cord-313312-h607itv2	223	30	pre	pre	JJ
cord-313312-h607itv2	223	31	-	-	JJ
cord-313312-h607itv2	223	32	existing	existing	JJ
cord-313312-h607itv2	223	33	antibodies	antibody	NNS
cord-313312-h607itv2	223	34	,	,	,
cord-313312-h607itv2	223	35	and	and	CC
cord-313312-h607itv2	223	36	even	even	RB
cord-313312-h607itv2	223	37	explore	explore	VB
cord-313312-h607itv2	223	38	the	the	DT
cord-313312-h607itv2	223	39	possibilities	possibility	NNS
cord-313312-h607itv2	223	40	of	of	IN
cord-313312-h607itv2	223	41	exploiting	exploit	VBG
cord-313312-h607itv2	223	42	pre	pre	JJ
cord-313312-h607itv2	223	43	-	-	JJ
cord-313312-h607itv2	223	44	existing	existing	JJ
cord-313312-h607itv2	223	45	antibodies	antibody	NNS
cord-313312-h607itv2	223	46	to	to	TO
cord-313312-h607itv2	223	47	promote	promote	VB
cord-313312-h607itv2	223	48	vaccine	vaccine	NN
cord-313312-h607itv2	223	49	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	223	50	and	and	CC
cord-313312-h607itv2	223	51	efficacy	efficacy	NN
cord-313312-h607itv2	223	52	.	.	.
cord-313312-h607itv2	224	1	It	-PRON-	PRP
cord-313312-h607itv2	224	2	would	would	MD
cord-313312-h607itv2	224	3	also	also	RB
cord-313312-h607itv2	224	4	be	be	VB
cord-313312-h607itv2	224	5	interesting	interesting	JJ
cord-313312-h607itv2	224	6	to	to	TO
cord-313312-h607itv2	224	7	determine	determine	VB
cord-313312-h607itv2	224	8	if	if	IN
cord-313312-h607itv2	224	9	cross	cross	JJ
cord-313312-h607itv2	224	10	-	-	JJ
cord-313312-h607itv2	224	11	reactive	reactive	JJ
cord-313312-h607itv2	224	12	antibodies	antibody	NNS
cord-313312-h607itv2	224	13	can	can	MD
cord-313312-h607itv2	224	14	impact	impact	VB
cord-313312-h607itv2	224	15	future	future	JJ
cord-313312-h607itv2	224	16	development	development	NN
cord-313312-h607itv2	224	17	of	of	IN
cord-313312-h607itv2	224	18	LAVs	lav	NNS
cord-313312-h607itv2	224	19	against	against	IN
cord-313312-h607itv2	224	20	newly	newly	RB
cord-313312-h607itv2	224	21	emerging	emerge	VBG
cord-313312-h607itv2	224	22	pandemic	pandemic	NN
cord-313312-h607itv2	224	23	viruses	virus	NNS
cord-313312-h607itv2	224	24	,	,	,
cord-313312-h607itv2	224	25	including	include	VBG
cord-313312-h607itv2	224	26	Ebola	Ebola	NNP
cord-313312-h607itv2	224	27	,	,	,
cord-313312-h607itv2	224	28	Severe	severe	JJ
cord-313312-h607itv2	224	29	Acute	acute	JJ
cord-313312-h607itv2	224	30	Respiratory	Respiratory	NNP
cord-313312-h607itv2	224	31	Syndrome	Syndrome	NNP
cord-313312-h607itv2	224	32	coronavirus-2	coronavirus-2	NNP
cord-313312-h607itv2	224	33	(	(	-LRB-
cord-313312-h607itv2	224	34	SARS	SARS	NNP
cord-313312-h607itv2	224	35	CoV-2	CoV-2	NNP
cord-313312-h607itv2	224	36	)	)	-RRB-
cord-313312-h607itv2	224	37	,	,	,
cord-313312-h607itv2	224	38	and	and	CC
cord-313312-h607itv2	224	39	Zika	Zika	NNP
cord-313312-h607itv2	224	40	viruses	virus	NNS
cord-313312-h607itv2	224	41	.	.	.
cord-313312-h607itv2	225	1	can	can	MD
cord-313312-h607itv2	225	2	impact	impact	VB
cord-313312-h607itv2	225	3	future	future	JJ
cord-313312-h607itv2	225	4	development	development	NN
cord-313312-h607itv2	225	5	of	of	IN
cord-313312-h607itv2	225	6	LAVs	lav	NNS
cord-313312-h607itv2	225	7	against	against	IN
cord-313312-h607itv2	225	8	newly	newly	RB
cord-313312-h607itv2	225	9	emerging	emerge	VBG
cord-313312-h607itv2	225	10	pandemic	pandemic	NN
cord-313312-h607itv2	225	11	viruses	virus	NNS
cord-313312-h607itv2	225	12	,	,	,
cord-313312-h607itv2	225	13	including	include	VBG
cord-313312-h607itv2	225	14	Ebola	Ebola	NNP
cord-313312-h607itv2	225	15	,	,	,
cord-313312-h607itv2	225	16	Severe	severe	JJ
cord-313312-h607itv2	225	17	Acute	acute	JJ
cord-313312-h607itv2	225	18	Respiratory	Respiratory	NNP
cord-313312-h607itv2	225	19	Syndrome	Syndrome	NNP
cord-313312-h607itv2	225	20	coronavirus-2	coronavirus-2	NNP
cord-313312-h607itv2	225	21	(	(	-LRB-
cord-313312-h607itv2	225	22	SARS	SARS	NNP
cord-313312-h607itv2	225	23	CoV-2	CoV-2	NNP
cord-313312-h607itv2	225	24	)	)	-RRB-
cord-313312-h607itv2	225	25	,	,	,
cord-313312-h607itv2	225	26	and	and	CC
cord-313312-h607itv2	225	27	Zika	Zika	NNP
cord-313312-h607itv2	225	28	viruses	virus	NNS
cord-313312-h607itv2	225	29	.	.	.
cord-313312-h607itv2	226	1	In	in	IN
cord-313312-h607itv2	226	2	the	the	DT
cord-313312-h607itv2	226	3	presence	presence	NN
cord-313312-h607itv2	226	4	of	of	IN
cord-313312-h607itv2	226	5	high	high	JJ
cord-313312-h607itv2	226	6	levels	level	NNS
cord-313312-h607itv2	226	7	of	of	IN
cord-313312-h607itv2	226	8	pre	pre	JJ
cord-313312-h607itv2	226	9	-	-	JJ
cord-313312-h607itv2	226	10	existing	existing	JJ
cord-313312-h607itv2	226	11	antibodies	antibody	NNS
cord-313312-h607itv2	226	12	or	or	CC
cord-313312-h607itv2	226	13	with	with	IN
cord-313312-h607itv2	226	14	potently	potently	RB
cord-313312-h607itv2	226	15	neutralizing	neutralize	VBG
cord-313312-h607itv2	226	16	antibodies	antibody	NNS
cord-313312-h607itv2	226	17	,	,	,
cord-313312-h607itv2	226	18	LAV	LAV	NNP
cord-313312-h607itv2	226	19	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	226	20	is	be	VBZ
cord-313312-h607itv2	226	21	hindered	hinder	VBN
cord-313312-h607itv2	226	22	due	due	IN
cord-313312-h607itv2	226	23	to	to	IN
cord-313312-h607itv2	226	24	immune	immune	JJ
cord-313312-h607itv2	226	25	interference	interference	NN
cord-313312-h607itv2	226	26	from	from	IN
cord-313312-h607itv2	226	27	virus	virus	NN
cord-313312-h607itv2	226	28	neutralization	neutralization	NN
cord-313312-h607itv2	226	29	or	or	CC
cord-313312-h607itv2	226	30	inhibition	inhibition	NN
cord-313312-h607itv2	226	31	of	of	IN
cord-313312-h607itv2	226	32	B	b	NN
cord-313312-h607itv2	226	33	-	-	HYPH
cord-313312-h607itv2	226	34	cell	cell	NN
cord-313312-h607itv2	226	35	responses	response	NNS
cord-313312-h607itv2	226	36	.	.	.
cord-313312-h607itv2	227	1	However	however	RB
cord-313312-h607itv2	227	2	,	,	,
cord-313312-h607itv2	227	3	at	at	IN
cord-313312-h607itv2	227	4	sub	sub	NN
cord-313312-h607itv2	227	5	-	-	JJ
cord-313312-h607itv2	227	6	neutralizing	neutralize	VBG
cord-313312-h607itv2	227	7	antibody	antibody	NN
cord-313312-h607itv2	227	8	titers	titer	NNS
cord-313312-h607itv2	227	9	,	,	,
cord-313312-h607itv2	227	10	there	there	EX
cord-313312-h607itv2	227	11	is	be	VBZ
cord-313312-h607itv2	227	12	a	a	DT
cord-313312-h607itv2	227	13	window	window	NN
cord-313312-h607itv2	227	14	of	of	IN
cord-313312-h607itv2	227	15	augmented	augment	VBN
cord-313312-h607itv2	227	16	vaccine	vaccine	NN
cord-313312-h607itv2	227	17	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	227	18	due	due	IN
cord-313312-h607itv2	227	19	to	to	IN
cord-313312-h607itv2	227	20	increased	increase	VBN
cord-313312-h607itv2	227	21	uptake	uptake	NN
cord-313312-h607itv2	227	22	into	into	IN
cord-313312-h607itv2	227	23	Fc	Fc	NNP
cord-313312-h607itv2	227	24	receptor	receptor	NN
cord-313312-h607itv2	227	25	-	-	HYPH
cord-313312-h607itv2	227	26	bearing	bear	VBG
cord-313312-h607itv2	227	27	cells	cell	NNS
cord-313312-h607itv2	227	28	and	and	CC
cord-313312-h607itv2	227	29	greater	great	JJR
cord-313312-h607itv2	227	30	induction	induction	NN
cord-313312-h607itv2	227	31	of	of	IN
cord-313312-h607itv2	227	32	innate	innate	JJ
cord-313312-h607itv2	227	33	immune	immune	JJ
cord-313312-h607itv2	227	34	responses	response	NNS
cord-313312-h607itv2	227	35	.	.	.
cord-313312-h607itv2	228	1	The	the	DT
cord-313312-h607itv2	228	2	horizontal	horizontal	JJ
cord-313312-h607itv2	228	3	dotted	dotted	JJ
cord-313312-h607itv2	228	4	line	line	NN
cord-313312-h607itv2	228	5	indicates	indicate	VBZ
cord-313312-h607itv2	228	6	LAV	LAV	NNP
cord-313312-h607itv2	228	7	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	228	8	in	in	IN
cord-313312-h607itv2	228	9	the	the	DT
cord-313312-h607itv2	228	10	absence	absence	NN
cord-313312-h607itv2	228	11	of	of	IN
cord-313312-h607itv2	228	12	pre	pre	JJ
cord-313312-h607itv2	228	13	-	-	JJ
cord-313312-h607itv2	228	14	existing	existing	JJ
cord-313312-h607itv2	228	15	antibodies	antibody	NNS
cord-313312-h607itv2	228	16	.	.	.
cord-313312-h607itv2	228	17	 	 	_SP
cord-313312-h607itv2	229	1	The	the	DT
cord-313312-h607itv2	229	2	First	First	NNP
cord-313312-h607itv2	229	3	Pandemic	Pandemic	NNP
cord-313312-h607itv2	229	4	of	of	IN
cord-313312-h607itv2	229	5	the	the	DT
cord-313312-h607itv2	229	6	21st	21st	JJ
cord-313312-h607itv2	229	7	Century	century	NN
cord-313312-h607itv2	229	8	:	:	:
cord-313312-h607itv2	229	9	Review	Review	NNP
cord-313312-h607itv2	229	10	of	of	IN
cord-313312-h607itv2	229	11	the	the	DT
cord-313312-h607itv2	229	12	2009	2009	CD
cord-313312-h607itv2	229	13	Pandemic	Pandemic	NNP
cord-313312-h607itv2	229	14	Variant	Variant	NNP
cord-313312-h607itv2	229	15	Influenza	Influenza	NNP
cord-313312-h607itv2	229	16	A	A	NNP
cord-313312-h607itv2	229	17	(	(	-LRB-
cord-313312-h607itv2	229	18	H1N1	H1N1	NNP
cord-313312-h607itv2	229	19	)	)	-RRB-
cord-313312-h607itv2	229	20	Virus	Virus	NNP
cord-313312-h607itv2	229	21	Resurgence	Resurgence	NNP
cord-313312-h607itv2	229	22	of	of	IN
cord-313312-h607itv2	229	23	Yellow	Yellow	NNP
cord-313312-h607itv2	229	24	Fever	Fever	NNP
cord-313312-h607itv2	229	25	in	in	IN
cord-313312-h607itv2	229	26	Angola	Angola	NNP
cord-313312-h607itv2	229	27	Transmission	Transmission	NNP
cord-313312-h607itv2	229	28	dynamics	dynamic	NNS
cord-313312-h607itv2	229	29	and	and	CC
cord-313312-h607itv2	229	30	control	control	NN
cord-313312-h607itv2	229	31	of	of	IN
cord-313312-h607itv2	229	32	Ebola	Ebola	NNP
cord-313312-h607itv2	229	33	virus	virus	NN
cord-313312-h607itv2	229	34	disease	disease	NN
cord-313312-h607itv2	229	35	(	(	-LRB-
cord-313312-h607itv2	229	36	EVD	EVD	NNP
cord-313312-h607itv2	229	37	)	)	-RRB-
cord-313312-h607itv2	229	38	:	:	:
cord-313312-h607itv2	230	1	A	a	DT
cord-313312-h607itv2	230	2	review	review	NN
cord-313312-h607itv2	231	1	Zika	Zika	NNP
cord-313312-h607itv2	231	2	virus	virus	NN
cord-313312-h607itv2	231	3	in	in	IN
cord-313312-h607itv2	231	4	the	the	DT
cord-313312-h607itv2	231	5	Americas-	Americas-	NNP
cord-313312-h607itv2	232	1	Yet	yet	RB
cord-313312-h607itv2	232	2	another	another	DT
cord-313312-h607itv2	232	3	arbovirus	arbovirus	NN
cord-313312-h607itv2	232	4	threat	threat	NN
cord-313312-h607itv2	232	5	Outbreak	outbreak	NN
cord-313312-h607itv2	232	6	of	of	IN
cord-313312-h607itv2	232	7	pneumonia	pneumonia	NN
cord-313312-h607itv2	232	8	of	of	IN
cord-313312-h607itv2	232	9	unknown	unknown	JJ
cord-313312-h607itv2	232	10	etiology	etiology	NN
cord-313312-h607itv2	232	11	in	in	IN
cord-313312-h607itv2	232	12	Wuhan	Wuhan	NNP
cord-313312-h607itv2	232	13	,	,	,
cord-313312-h607itv2	232	14	China	China	NNP
cord-313312-h607itv2	232	15	:	:	:
cord-313312-h607itv2	233	1	The	the	DT
cord-313312-h607itv2	233	2	mystery	mystery	NN
cord-313312-h607itv2	233	3	and	and	CC
cord-313312-h607itv2	233	4	the	the	DT
cord-313312-h607itv2	233	5	miracle	miracle	NN
cord-313312-h607itv2	233	6	Epidemiology	epidemiology	NN
cord-313312-h607itv2	233	7	and	and	CC
cord-313312-h607itv2	233	8	ecology	ecology	NN
cord-313312-h607itv2	233	9	of	of	IN
cord-313312-h607itv2	233	10	yellow	yellow	JJ
cord-313312-h607itv2	233	11	fever	fever	NN
cord-313312-h607itv2	233	12	virus	virus	NN
cord-313312-h607itv2	234	1	A	a	DT
cord-313312-h607itv2	234	2	Decade	decade	NN
cord-313312-h607itv2	234	3	of	of	IN
cord-313312-h607itv2	234	4	Vaccines	vaccine	NNS
cord-313312-h607itv2	234	5	:	:	:
cord-313312-h607itv2	235	1	Integrating	integrate	VBG
cord-313312-h607itv2	235	2	Immunology	Immunology	NNP
cord-313312-h607itv2	235	3	and	and	CC
cord-313312-h607itv2	235	4	Vaccinology	Vaccinology	NNP
cord-313312-h607itv2	235	5	for	for	IN
cord-313312-h607itv2	235	6	Rational	Rational	NNP
cord-313312-h607itv2	235	7	Vaccine	Vaccine	NNP
cord-313312-h607itv2	235	8	Design	Design	NNP
cord-313312-h607itv2	235	9	Declaration	Declaration	NNP
cord-313312-h607itv2	235	10	of	of	IN
cord-313312-h607itv2	235	11	global	global	JJ
cord-313312-h607itv2	235	12	eradication	eradication	NN
cord-313312-h607itv2	235	13	of	of	IN
cord-313312-h607itv2	235	14	smallpox	smallpox	NN
cord-313312-h607itv2	235	15	State	State	NNP
cord-313312-h607itv2	235	16	of	of	IN
cord-313312-h607itv2	235	17	the	the	DT
cord-313312-h607itv2	235	18	World	World	NNP
cord-313312-h607itv2	235	19	's	's	POS
cord-313312-h607itv2	235	20	Vaccines	Vaccines	NNPS
cord-313312-h607itv2	235	21	and	and	CC
cord-313312-h607itv2	235	22	Immunization	Immunization	NNP
cord-313312-h607itv2	236	1	The	the	DT
cord-313312-h607itv2	236	2	First	First	NNP
cord-313312-h607itv2	236	3	Pandemic	Pandemic	NNP
cord-313312-h607itv2	236	4	of	of	IN
cord-313312-h607itv2	236	5	the	the	DT
cord-313312-h607itv2	236	6	21st	21st	JJ
cord-313312-h607itv2	236	7	Century	century	NN
cord-313312-h607itv2	236	8	:	:	:
cord-313312-h607itv2	236	9	Review	Review	NNP
cord-313312-h607itv2	236	10	of	of	IN
cord-313312-h607itv2	236	11	the	the	DT
cord-313312-h607itv2	236	12	2009	2009	CD
cord-313312-h607itv2	236	13	Pandemic	Pandemic	NNP
cord-313312-h607itv2	236	14	Variant	Variant	NNP
cord-313312-h607itv2	236	15	Influenza	Influenza	NNP
cord-313312-h607itv2	236	16	A	A	NNP
cord-313312-h607itv2	236	17	(	(	-LRB-
cord-313312-h607itv2	236	18	H1N1	H1N1	NNP
cord-313312-h607itv2	236	19	)	)	-RRB-
cord-313312-h607itv2	236	20	Virus	Virus	NNP
cord-313312-h607itv2	236	21	Resurgence	Resurgence	NNP
cord-313312-h607itv2	236	22	of	of	IN
cord-313312-h607itv2	236	23	Yellow	Yellow	NNP
cord-313312-h607itv2	236	24	Fever	Fever	NNP
cord-313312-h607itv2	236	25	in	in	IN
cord-313312-h607itv2	236	26	Angola	Angola	NNP
cord-313312-h607itv2	236	27	Transmission	Transmission	NNP
cord-313312-h607itv2	236	28	dynamics	dynamic	NNS
cord-313312-h607itv2	236	29	and	and	CC
cord-313312-h607itv2	236	30	control	control	NN
cord-313312-h607itv2	236	31	of	of	IN
cord-313312-h607itv2	236	32	Ebola	Ebola	NNP
cord-313312-h607itv2	236	33	virus	virus	NN
cord-313312-h607itv2	236	34	disease	disease	NN
cord-313312-h607itv2	236	35	(	(	-LRB-
cord-313312-h607itv2	236	36	EVD	EVD	NNP
cord-313312-h607itv2	236	37	)	)	-RRB-
cord-313312-h607itv2	236	38	:	:	:
cord-313312-h607itv2	237	1	A	a	DT
cord-313312-h607itv2	237	2	review	review	NN
cord-313312-h607itv2	238	1	Zika	Zika	NNP
cord-313312-h607itv2	238	2	virus	virus	NN
cord-313312-h607itv2	238	3	in	in	IN
cord-313312-h607itv2	238	4	the	the	DT
cord-313312-h607itv2	238	5	Americas-	Americas-	NNP
cord-313312-h607itv2	239	1	Yet	yet	RB
cord-313312-h607itv2	239	2	another	another	DT
cord-313312-h607itv2	239	3	arbovirus	arbovirus	NN
cord-313312-h607itv2	239	4	threat	threat	NN
cord-313312-h607itv2	239	5	Outbreak	outbreak	NN
cord-313312-h607itv2	239	6	of	of	IN
cord-313312-h607itv2	239	7	pneumonia	pneumonia	NN
cord-313312-h607itv2	239	8	of	of	IN
cord-313312-h607itv2	239	9	unknown	unknown	JJ
cord-313312-h607itv2	239	10	etiology	etiology	NN
cord-313312-h607itv2	239	11	in	in	IN
cord-313312-h607itv2	239	12	Wuhan	Wuhan	NNP
cord-313312-h607itv2	239	13	,	,	,
cord-313312-h607itv2	239	14	China	China	NNP
cord-313312-h607itv2	239	15	:	:	:
cord-313312-h607itv2	240	1	The	the	DT
cord-313312-h607itv2	240	2	mystery	mystery	NN
cord-313312-h607itv2	240	3	and	and	CC
cord-313312-h607itv2	240	4	the	the	DT
cord-313312-h607itv2	240	5	miracle	miracle	NN
cord-313312-h607itv2	240	6	Epidemiology	epidemiology	NN
cord-313312-h607itv2	240	7	and	and	CC
cord-313312-h607itv2	240	8	ecology	ecology	NN
cord-313312-h607itv2	240	9	of	of	IN
cord-313312-h607itv2	240	10	yellow	yellow	JJ
cord-313312-h607itv2	240	11	fever	fever	NN
cord-313312-h607itv2	240	12	virus	virus	NN
cord-313312-h607itv2	241	1	A	a	DT
cord-313312-h607itv2	241	2	Decade	decade	NN
cord-313312-h607itv2	241	3	of	of	IN
cord-313312-h607itv2	241	4	Vaccines	vaccine	NNS
cord-313312-h607itv2	241	5	:	:	:
cord-313312-h607itv2	242	1	Integrating	integrate	VBG
cord-313312-h607itv2	242	2	Immunology	Immunology	NNP
cord-313312-h607itv2	242	3	and	and	CC
cord-313312-h607itv2	242	4	Vaccinology	Vaccinology	NNP
cord-313312-h607itv2	242	5	for	for	IN
cord-313312-h607itv2	242	6	Rational	Rational	NNP
cord-313312-h607itv2	242	7	Vaccine	Vaccine	NNP
cord-313312-h607itv2	242	8	Design	Design	NNP
cord-313312-h607itv2	242	9	Declaration	Declaration	NNP
cord-313312-h607itv2	242	10	of	of	IN
cord-313312-h607itv2	242	11	global	global	JJ
cord-313312-h607itv2	242	12	eradication	eradication	NN
cord-313312-h607itv2	242	13	of	of	IN
cord-313312-h607itv2	242	14	smallpox	smallpox	NN
cord-313312-h607itv2	242	15	State	State	NNP
cord-313312-h607itv2	242	16	of	of	IN
cord-313312-h607itv2	242	17	the	the	DT
cord-313312-h607itv2	242	18	World	World	NNP
cord-313312-h607itv2	242	19	's	's	POS
cord-313312-h607itv2	242	20	Vaccines	Vaccines	NNPS
cord-313312-h607itv2	242	21	and	and	CC
cord-313312-h607itv2	242	22	Immunization	Immunization	NNP
cord-313312-h607itv2	242	23	,	,	,
cord-313312-h607itv2	242	24	Geneva	Geneva	NNP
cord-313312-h607itv2	242	25	;	;	:
cord-313312-h607itv2	242	26	World	World	NNP
cord-313312-h607itv2	242	27	Health	Health	NNP
cord-313312-h607itv2	242	28	Organization	Organization	NNP
cord-313312-h607itv2	242	29	Estimated	estimate	VBD
cord-313312-h607itv2	242	30	economic	economic	JJ
cord-313312-h607itv2	242	31	benefits	benefit	NNS
cord-313312-h607itv2	242	32	during	during	IN
cord-313312-h607itv2	242	33	the	the	DT
cord-313312-h607itv2	242	34	'	'	''
cord-313312-h607itv2	242	35	decade	decade	NN
cord-313312-h607itv2	242	36	of	of	IN
cord-313312-h607itv2	242	37	vaccines	vaccine	NNS
cord-313312-h607itv2	242	38	'	'	''
cord-313312-h607itv2	242	39	include	include	VBP
cord-313312-h607itv2	242	40	treatment	treatment	NN
cord-313312-h607itv2	242	41	savings	saving	NNS
cord-313312-h607itv2	242	42	,	,	,
cord-313312-h607itv2	242	43	gains	gain	NNS
cord-313312-h607itv2	242	44	in	in	IN
cord-313312-h607itv2	242	45	labor	labor	NN
cord-313312-h607itv2	242	46	productivity	productivity	NN
cord-313312-h607itv2	242	47	Anti	Anti	NNP
cord-313312-h607itv2	242	48	-	-	NNP
cord-313312-h607itv2	242	49	Vaccine	Vaccine	NNP
cord-313312-h607itv2	242	50	Decision	decision	NN
cord-313312-h607itv2	242	51	-	-	HYPH
cord-313312-h607itv2	242	52	Making	making	NN
cord-313312-h607itv2	242	53	and	and	CC
cord-313312-h607itv2	242	54	Measles	Measles	NNP
cord-313312-h607itv2	242	55	Resurgence	Resurgence	NNP
cord-313312-h607itv2	242	56	in	in	IN
cord-313312-h607itv2	242	57	the	the	DT
cord-313312-h607itv2	242	58	United	United	NNP
cord-313312-h607itv2	242	59	States	States	NNP
cord-313312-h607itv2	243	1	Recent	recent	JJ
cord-313312-h607itv2	243	2	advances	advance	NNS
cord-313312-h607itv2	243	3	in	in	IN
cord-313312-h607itv2	243	4	antigen	antigen	NN
cord-313312-h607itv2	243	5	processing	processing	NN
cord-313312-h607itv2	243	6	and	and	CC
cord-313312-h607itv2	243	7	presentation	presentation	NN
cord-313312-h607itv2	243	8	Live	live	VB
cord-313312-h607itv2	243	9	attenuated	attenuated	JJ
cord-313312-h607itv2	243	10	vaccines	vaccine	NNS
cord-313312-h607itv2	243	11	:	:	:
cord-313312-h607itv2	243	12	Influenza	influenza	NN
cord-313312-h607itv2	243	13	,	,	,
cord-313312-h607itv2	243	14	rotavirus	rotavirus	NN
cord-313312-h607itv2	243	15	and	and	CC
cord-313312-h607itv2	243	16	varicella	varicella	NN
cord-313312-h607itv2	243	17	zoster	zoster	NN
cord-313312-h607itv2	243	18	virus	virus	NN
cord-313312-h607itv2	243	19	Novel	Novel	NNP
cord-313312-h607itv2	243	20	viral	viral	JJ
cord-313312-h607itv2	243	21	vectors	vector	NNS
cord-313312-h607itv2	243	22	in	in	IN
cord-313312-h607itv2	243	23	infectious	infectious	JJ
cord-313312-h607itv2	243	24	diseases	disease	NNS
cord-313312-h607itv2	244	1	Viral	viral	JJ
cord-313312-h607itv2	244	2	vector	vector	NN
cord-313312-h607itv2	244	3	-	-	HYPH
cord-313312-h607itv2	244	4	based	base	VBN
cord-313312-h607itv2	244	5	therapeutic	therapeutic	JJ
cord-313312-h607itv2	244	6	cancer	cancer	NN
cord-313312-h607itv2	244	7	vaccines	vaccine	NNS
cord-313312-h607itv2	244	8	Safety	Safety	NNP
cord-313312-h607itv2	244	9	and	and	CC
cord-313312-h607itv2	244	10	Efficacy	Efficacy	NNP
cord-313312-h607itv2	244	11	of	of	IN
cord-313312-h607itv2	244	12	Chimeric	Chimeric	NNP
cord-313312-h607itv2	244	13	Yellow	Yellow	NNP
cord-313312-h607itv2	244	14	Fever	Fever	NNP
cord-313312-h607itv2	244	15	-	-	HYPH
cord-313312-h607itv2	244	16	Dengue	Dengue	NNP
cord-313312-h607itv2	244	17	Virus	Virus	NNP
cord-313312-h607itv2	244	18	Tetravalent	Tetravalent	NNP
cord-313312-h607itv2	244	19	Vaccine	Vaccine	NNP
cord-313312-h607itv2	244	20	Formulations	Formulations	NNPS
cord-313312-h607itv2	244	21	in	in	IN
cord-313312-h607itv2	244	22	Nonhuman	Nonhuman	NNP
cord-313312-h607itv2	244	23	Primates	Primates	NNPS
cord-313312-h607itv2	244	24	Efficacy	Efficacy	NNP
cord-313312-h607itv2	244	25	and	and	CC
cord-313312-h607itv2	244	26	long	long	JJ
cord-313312-h607itv2	244	27	-	-	HYPH
cord-313312-h607itv2	244	28	term	term	NN
cord-313312-h607itv2	244	29	safety	safety	NN
cord-313312-h607itv2	244	30	of	of	IN
cord-313312-h607itv2	244	31	a	a	DT
cord-313312-h607itv2	244	32	dengue	dengue	NN
cord-313312-h607itv2	244	33	vaccine	vaccine	NN
cord-313312-h607itv2	244	34	in	in	IN
cord-313312-h607itv2	244	35	regions	region	NNS
cord-313312-h607itv2	244	36	of	of	IN
cord-313312-h607itv2	244	37	endemic	endemic	JJ
cord-313312-h607itv2	244	38	disease	disease	NN
cord-313312-h607itv2	244	39	A	a	DT
cord-313312-h607itv2	244	40	framework	framework	NN
cord-313312-h607itv2	244	41	for	for	IN
cord-313312-h607itv2	244	42	Controlled	Controlled	NNP
cord-313312-h607itv2	244	43	Human	Human	NNP
cord-313312-h607itv2	244	44	Infection	Infection	NNP
cord-313312-h607itv2	244	45	Model	Model	NNP
cord-313312-h607itv2	244	46	(	(	-LRB-
cord-313312-h607itv2	244	47	CHIM	CHIM	NNP
cord-313312-h607itv2	244	48	)	)	-RRB-
cord-313312-h607itv2	244	49	studies	study	NNS
cord-313312-h607itv2	244	50	in	in	IN
cord-313312-h607itv2	244	51	Malawi	Malawi	NNP
cord-313312-h607itv2	244	52	:	:	:
cord-313312-h607itv2	244	53	Report	Report	NNP
cord-313312-h607itv2	244	54	of	of	IN
cord-313312-h607itv2	244	55	a	a	DT
cord-313312-h607itv2	244	56	Wellcome	Wellcome	NNP
cord-313312-h607itv2	244	57	Trust	Trust	NNP
cord-313312-h607itv2	244	58	workshop	workshop	NN
cord-313312-h607itv2	244	59	on	on	IN
cord-313312-h607itv2	244	60	CHIM	CHIM	NNP
cord-313312-h607itv2	244	61	in	in	IN
cord-313312-h607itv2	244	62	Low	Low	NNP
cord-313312-h607itv2	244	63	Income	Income	NNP
cord-313312-h607itv2	244	64	Countries	Countries	NNPS
cord-313312-h607itv2	244	65	Effect	Effect	NNP
cord-313312-h607itv2	244	66	of	of	IN
cord-313312-h607itv2	244	67	a	a	DT
cord-313312-h607itv2	244	68	prepregnancy	prepregnancy	NN
cord-313312-h607itv2	244	69	pertussis	pertussis	NN
cord-313312-h607itv2	244	70	booster	booster	NN
cord-313312-h607itv2	244	71	dose	dose	NN
cord-313312-h607itv2	244	72	on	on	IN
cord-313312-h607itv2	244	73	maternal	maternal	JJ
cord-313312-h607itv2	244	74	antibody	antibody	NN
cord-313312-h607itv2	244	75	titers	titer	NNS
cord-313312-h607itv2	244	76	in	in	IN
cord-313312-h607itv2	244	77	young	young	JJ
cord-313312-h607itv2	244	78	infants	infant	NNS
cord-313312-h607itv2	245	1	Passive	passive	JJ
cord-313312-h607itv2	245	2	transmission	transmission	NN
cord-313312-h607itv2	245	3	and	and	CC
cord-313312-h607itv2	245	4	persistence	persistence	NN
cord-313312-h607itv2	245	5	of	of	IN
cord-313312-h607itv2	245	6	naturally	naturally	RB
cord-313312-h607itv2	245	7	acquired	acquire	VBN
cord-313312-h607itv2	245	8	or	or	CC
cord-313312-h607itv2	245	9	vaccine	vaccine	NN
cord-313312-h607itv2	245	10	-	-	HYPH
cord-313312-h607itv2	245	11	induced	induce	VBN
cord-313312-h607itv2	245	12	maternal	maternal	JJ
cord-313312-h607itv2	245	13	antibodies	antibody	NNS
cord-313312-h607itv2	245	14	against	against	IN
cord-313312-h607itv2	245	15	measles	measle	NNS
cord-313312-h607itv2	245	16	in	in	IN
cord-313312-h607itv2	245	17	newborns	newborn	NNS
cord-313312-h607itv2	246	1	The	the	DT
cord-313312-h607itv2	246	2	clinical	clinical	JJ
cord-313312-h607itv2	246	3	significance	significance	NN
cord-313312-h607itv2	246	4	of	of	IN
cord-313312-h607itv2	246	5	measles	measle	NNS
cord-313312-h607itv2	246	6	:	:	:
cord-313312-h607itv2	246	7	A	a	DT
cord-313312-h607itv2	246	8	review	review	NN
cord-313312-h607itv2	246	9	Medical	medical	JJ
cord-313312-h607itv2	246	10	importance	importance	NN
cord-313312-h607itv2	246	11	of	of	IN
cord-313312-h607itv2	246	12	measles	measle	NNS
cord-313312-h607itv2	246	13	Observations	observation	NNS
cord-313312-h607itv2	246	14	on	on	IN
cord-313312-h607itv2	246	15	the	the	DT
cord-313312-h607itv2	246	16	seroepidemiology	seroepidemiology	NN
cord-313312-h607itv2	246	17	of	of	IN
cord-313312-h607itv2	246	18	measles	measle	NNS
cord-313312-h607itv2	246	19	Pathological	pathological	JJ
cord-313312-h607itv2	246	20	consequences	consequence	NNS
cord-313312-h607itv2	246	21	of	of	IN
cord-313312-h607itv2	246	22	systemic	systemic	JJ
cord-313312-h607itv2	246	23	measles	measle	NNS
cord-313312-h607itv2	246	24	virus	virus	NN
cord-313312-h607itv2	246	25	infection	infection	NN
cord-313312-h607itv2	247	1	The	the	DT
cord-313312-h607itv2	247	2	first	first	JJ
cord-313312-h607itv2	247	3	measles	measles	NN
cord-313312-h607itv2	247	4	vaccine	vaccine	NN
cord-313312-h607itv2	247	5	Progress	Progress	NNP
cord-313312-h607itv2	247	6	in	in	IN
cord-313312-h607itv2	247	7	global	global	JJ
cord-313312-h607itv2	247	8	measles	measle	NNS
cord-313312-h607itv2	247	9	control	control	NN
cord-313312-h607itv2	247	10	and	and	CC
cord-313312-h607itv2	247	11	mortality	mortality	NN
cord-313312-h607itv2	247	12	reduction	reduction	NN
cord-313312-h607itv2	248	1	The	the	DT
cord-313312-h607itv2	248	2	global	global	JJ
cord-313312-h607itv2	248	3	burden	burden	NN
cord-313312-h607itv2	248	4	of	of	IN
cord-313312-h607itv2	248	5	measles	measle	NNS
cord-313312-h607itv2	248	6	in	in	IN
cord-313312-h607itv2	248	7	the	the	DT
cord-313312-h607itv2	248	8	year	year	NN
cord-313312-h607itv2	248	9	2000-A	2000-a	CD
cord-313312-h607itv2	248	10	model	model	NN
cord-313312-h607itv2	248	11	that	that	WDT
cord-313312-h607itv2	248	12	uses	use	VBZ
cord-313312-h607itv2	248	13	country	country	NN
cord-313312-h607itv2	248	14	-	-	HYPH
cord-313312-h607itv2	248	15	specific	specific	JJ
cord-313312-h607itv2	248	16	indicators	indicator	NNS
cord-313312-h607itv2	248	17	Estimates	estimate	NNS
cord-313312-h607itv2	248	18	of	of	IN
cord-313312-h607itv2	248	19	case	case	NN
cord-313312-h607itv2	248	20	-	-	HYPH
cord-313312-h607itv2	248	21	fatality	fatality	NN
cord-313312-h607itv2	248	22	ratios	ratio	NNS
cord-313312-h607itv2	248	23	of	of	IN
cord-313312-h607itv2	248	24	measles	measle	NNS
cord-313312-h607itv2	248	25	in	in	IN
cord-313312-h607itv2	248	26	low	low	JJ
cord-313312-h607itv2	248	27	-	-	HYPH
cord-313312-h607itv2	248	28	income	income	NN
cord-313312-h607itv2	248	29	and	and	CC
cord-313312-h607itv2	248	30	middle	middle	JJ
cord-313312-h607itv2	248	31	-	-	HYPH
cord-313312-h607itv2	248	32	income	income	NN
cord-313312-h607itv2	248	33	countries	country	NNS
cord-313312-h607itv2	248	34	:	:	:
cord-313312-h607itv2	249	1	A	a	DT
cord-313312-h607itv2	249	2	systematic	systematic	JJ
cord-313312-h607itv2	249	3	review	review	NN
cord-313312-h607itv2	249	4	and	and	CC
cord-313312-h607itv2	249	5	modelling	modelling	NN
cord-313312-h607itv2	249	6	analysis	analysis	NN
cord-313312-h607itv2	249	7	Propagation	propagation	NN
cord-313312-h607itv2	249	8	in	in	IN
cord-313312-h607itv2	249	9	tissue	tissue	NN
cord-313312-h607itv2	249	10	cultures	culture	NNS
cord-313312-h607itv2	249	11	of	of	IN
cord-313312-h607itv2	249	12	cytopathogenic	cytopathogenic	JJ
cord-313312-h607itv2	249	13	agents	agent	NNS
cord-313312-h607itv2	249	14	from	from	IN
cord-313312-h607itv2	249	15	patients	patient	NNS
cord-313312-h607itv2	249	16	with	with	IN
cord-313312-h607itv2	249	17	measles	measle	NNS
cord-313312-h607itv2	249	18	Measles	Measles	NNP
cord-313312-h607itv2	249	19	vaccines	vaccine	NNS
cord-313312-h607itv2	249	20	:	:	:
cord-313312-h607itv2	250	1	WHO	who	WP
cord-313312-h607itv2	250	2	position	position	VBP
cord-313312-h607itv2	250	3	paper	paper	NN
cord-313312-h607itv2	250	4	Comparative	comparative	JJ
cord-313312-h607itv2	250	5	analysis	analysis	NN
cord-313312-h607itv2	250	6	of	of	IN
cord-313312-h607itv2	250	7	titers	titer	NNS
cord-313312-h607itv2	250	8	of	of	IN
cord-313312-h607itv2	250	9	antibody	antibody	NN
cord-313312-h607itv2	250	10	against	against	IN
cord-313312-h607itv2	250	11	measles	measles	NNP
cord-313312-h607itv2	250	12	virus	virus	NN
cord-313312-h607itv2	250	13	in	in	IN
cord-313312-h607itv2	250	14	sera	sera	NNP
cord-313312-h607itv2	250	15	of	of	IN
cord-313312-h607itv2	250	16	vaccinated	vaccinate	VBN
cord-313312-h607itv2	250	17	and	and	CC
cord-313312-h607itv2	250	18	naturally	naturally	RB
cord-313312-h607itv2	250	19	infected	infect	VBN
cord-313312-h607itv2	250	20	Japanese	japanese	JJ
cord-313312-h607itv2	250	21	individuals	individual	NNS
cord-313312-h607itv2	250	22	of	of	IN
cord-313312-h607itv2	250	23	different	different	JJ
cord-313312-h607itv2	250	24	age	age	NN
cord-313312-h607itv2	250	25	groups	group	NNS
cord-313312-h607itv2	250	26	Persistence	persistence	NN
cord-313312-h607itv2	250	27	of	of	IN
cord-313312-h607itv2	250	28	vaccine	vaccine	NN
cord-313312-h607itv2	250	29	-	-	HYPH
cord-313312-h607itv2	250	30	induced	induce	VBN
cord-313312-h607itv2	250	31	antibody	antibody	NN
cord-313312-h607itv2	250	32	to	to	IN
cord-313312-h607itv2	250	33	measles	measle	NNS
cord-313312-h607itv2	250	34	26	26	CD
cord-313312-h607itv2	250	35	-	-	SYM
cord-313312-h607itv2	250	36	33	33	CD
cord-313312-h607itv2	250	37	years	year	NNS
cord-313312-h607itv2	250	38	after	after	IN
cord-313312-h607itv2	250	39	vaccination	vaccination	NN
cord-313312-h607itv2	250	40	Relevance	relevance	NN
cord-313312-h607itv2	250	41	of	of	IN
cord-313312-h607itv2	250	42	a	a	DT
cord-313312-h607itv2	250	43	pre	pre	JJ
cord-313312-h607itv2	250	44	-	-	JJ
cord-313312-h607itv2	250	45	existing	existing	JJ
cord-313312-h607itv2	250	46	measles	measle	NNS
cord-313312-h607itv2	250	47	immunity	immunity	NN
cord-313312-h607itv2	250	48	prior	prior	JJ
cord-313312-h607itv2	250	49	immunization	immunization	NN
cord-313312-h607itv2	250	50	with	with	IN
cord-313312-h607itv2	250	51	a	a	DT
cord-313312-h607itv2	250	52	recombinant	recombinant	JJ
cord-313312-h607itv2	250	53	measles	measles	NN
cord-313312-h607itv2	250	54	virus	virus	NN
cord-313312-h607itv2	250	55	vector	vector	NN
cord-313312-h607itv2	250	56	Elevation	Elevation	NNP
cord-313312-h607itv2	250	57	of	of	IN
cord-313312-h607itv2	250	58	cord	cord	NN
cord-313312-h607itv2	250	59	over	over	IN
cord-313312-h607itv2	250	60	maternal	maternal	JJ
cord-313312-h607itv2	250	61	IgG	igg	NN
cord-313312-h607itv2	250	62	immunoglobulin	immunoglobulin	NN
cord-313312-h607itv2	250	63	:	:	:
cord-313312-h607itv2	250	64	Evidence	evidence	NN
cord-313312-h607itv2	250	65	for	for	IN
cord-313312-h607itv2	250	66	an	an	DT
cord-313312-h607itv2	250	67	active	active	JJ
cord-313312-h607itv2	250	68	placental	placental	JJ
cord-313312-h607itv2	250	69	IgG	igg	NN
cord-313312-h607itv2	250	70	transport	transport	NN
cord-313312-h607itv2	250	71	Measles	Measles	NNP
cord-313312-h607itv2	250	72	immunization	immunization	NN
cord-313312-h607itv2	250	73	.	.	.
cord-313312-h607itv2	251	1	Successes	success	NNS
cord-313312-h607itv2	251	2	and	and	CC
cord-313312-h607itv2	251	3	failures	failure	NNS
cord-313312-h607itv2	251	4	Persistence	persistence	NN
cord-313312-h607itv2	251	5	of	of	IN
cord-313312-h607itv2	251	6	maternal	maternal	JJ
cord-313312-h607itv2	251	7	antibody	antibody	NN
cord-313312-h607itv2	251	8	in	in	IN
cord-313312-h607itv2	251	9	infants	infant	NNS
cord-313312-h607itv2	251	10	beyond	beyond	IN
cord-313312-h607itv2	251	11	12	12	CD
cord-313312-h607itv2	251	12	months	month	NNS
cord-313312-h607itv2	251	13	:	:	:
cord-313312-h607itv2	251	14	Mechanism	mechanism	NN
cord-313312-h607itv2	251	15	of	of	IN
cord-313312-h607itv2	251	16	measles	measle	NNS
cord-313312-h607itv2	251	17	vaccine	vaccine	NN
cord-313312-h607itv2	251	18	failure	failure	NN
cord-313312-h607itv2	251	19	Clinical	clinical	JJ
cord-313312-h607itv2	251	20	efficacy	efficacy	NN
cord-313312-h607itv2	251	21	of	of	IN
cord-313312-h607itv2	251	22	measles	measle	NNS
cord-313312-h607itv2	251	23	vaccine	vaccine	NN
cord-313312-h607itv2	251	24	during	during	IN
cord-313312-h607itv2	251	25	the	the	DT
cord-313312-h607itv2	251	26	1990	1990	CD
cord-313312-h607itv2	251	27	measles	measle	NNS
cord-313312-h607itv2	251	28	epidemic	epidemic	NN
cord-313312-h607itv2	251	29	Appropriate	appropriate	JJ
cord-313312-h607itv2	251	30	age	age	NN
cord-313312-h607itv2	251	31	for	for	IN
cord-313312-h607itv2	251	32	measles	measle	NNS
cord-313312-h607itv2	251	33	vaccination	vaccination	NN
cord-313312-h607itv2	251	34	in	in	IN
cord-313312-h607itv2	251	35	the	the	DT
cord-313312-h607itv2	251	36	United	United	NNP
cord-313312-h607itv2	251	37	States	States	NNP
cord-313312-h607itv2	251	38	Measles	Measles	NNP
cord-313312-h607itv2	251	39	vaccination	vaccination	NN
cord-313312-h607itv2	251	40	in	in	IN
cord-313312-h607itv2	251	41	the	the	DT
cord-313312-h607itv2	251	42	presence	presence	NN
cord-313312-h607itv2	251	43	or	or	CC
cord-313312-h607itv2	251	44	absence	absence	NN
cord-313312-h607itv2	251	45	of	of	IN
cord-313312-h607itv2	251	46	maternal	maternal	JJ
cord-313312-h607itv2	251	47	measles	measles	NN
cord-313312-h607itv2	251	48	antibody	antibody	NN
cord-313312-h607itv2	251	49	:	:	:
cord-313312-h607itv2	251	50	Impact	impact	NN
cord-313312-h607itv2	251	51	on	on	IN
cord-313312-h607itv2	251	52	child	child	NN
cord-313312-h607itv2	251	53	survival	survival	NN
cord-313312-h607itv2	251	54	Protective	protective	JJ
cord-313312-h607itv2	251	55	immunity	immunity	NN
cord-313312-h607itv2	251	56	in	in	IN
cord-313312-h607itv2	251	57	macaques	macaque	NNS
cord-313312-h607itv2	251	58	vaccinated	vaccinate	VBN
cord-313312-h607itv2	251	59	with	with	IN
cord-313312-h607itv2	251	60	live	live	JJ
cord-313312-h607itv2	251	61	attenuated	attenuated	JJ
cord-313312-h607itv2	251	62	,	,	,
cord-313312-h607itv2	251	63	recombinant	recombinant	JJ
cord-313312-h607itv2	251	64	,	,	,
cord-313312-h607itv2	251	65	and	and	CC
cord-313312-h607itv2	251	66	subunit	subunit	NN
cord-313312-h607itv2	251	67	measles	measles	NN
cord-313312-h607itv2	251	68	vaccines	vaccine	NNS
cord-313312-h607itv2	251	69	in	in	IN
cord-313312-h607itv2	251	70	the	the	DT
cord-313312-h607itv2	251	71	presence	presence	NN
cord-313312-h607itv2	251	72	of	of	IN
cord-313312-h607itv2	251	73	passively	passively	RB
cord-313312-h607itv2	251	74	acquired	acquire	VBN
cord-313312-h607itv2	251	75	antibodies	antibody	NNS
cord-313312-h607itv2	251	76	Humoral	Humoral	NNP
cord-313312-h607itv2	251	77	and	and	CC
cord-313312-h607itv2	251	78	cell	cell	NN
cord-313312-h607itv2	251	79	-	-	HYPH
cord-313312-h607itv2	251	80	mediated	mediate	VBN
cord-313312-h607itv2	251	81	immune	immune	JJ
cord-313312-h607itv2	251	82	responses	response	NNS
cord-313312-h607itv2	251	83	to	to	IN
cord-313312-h607itv2	251	84	an	an	DT
cord-313312-h607itv2	251	85	early	early	JJ
cord-313312-h607itv2	251	86	2-dose	2-dose	CD
cord-313312-h607itv2	251	87	measles	measle	NNS
cord-313312-h607itv2	251	88	vaccination	vaccination	NN
cord-313312-h607itv2	251	89	regimen	regimen	NN
cord-313312-h607itv2	251	90	in	in	IN
cord-313312-h607itv2	251	91	the	the	DT
cord-313312-h607itv2	251	92	United	United	NNP
cord-313312-h607itv2	251	93	States	States	NNP
cord-313312-h607itv2	251	94	Immune	Immune	NNP
cord-313312-h607itv2	251	95	responses	response	NNS
cord-313312-h607itv2	251	96	to	to	IN
cord-313312-h607itv2	251	97	adenovirus	adenovirus	NN
cord-313312-h607itv2	251	98	and	and	CC
cord-313312-h607itv2	251	99	adeno	adeno	NN
cord-313312-h607itv2	251	100	-	-	HYPH
cord-313312-h607itv2	251	101	associated	associate	VBN
cord-313312-h607itv2	251	102	virus	virus	NN
cord-313312-h607itv2	251	103	in	in	IN
cord-313312-h607itv2	251	104	humans	human	NNS
cord-313312-h607itv2	251	105	International	international	JJ
cord-313312-h607itv2	251	106	epidemiology	epidemiology	NN
cord-313312-h607itv2	251	107	of	of	IN
cord-313312-h607itv2	251	108	human	human	JJ
cord-313312-h607itv2	251	109	pre	pre	JJ
cord-313312-h607itv2	251	110	-	-	JJ
cord-313312-h607itv2	251	111	existing	existing	JJ
cord-313312-h607itv2	251	112	adenovirus	adenovirus	NN
cord-313312-h607itv2	251	113	(	(	-LRB-
cord-313312-h607itv2	251	114	Ad	ad	NN
cord-313312-h607itv2	251	115	)	)	-RRB-
cord-313312-h607itv2	251	116	type-5	type-5	NNP
cord-313312-h607itv2	251	117	,	,	,
cord-313312-h607itv2	251	118	type-6	type-6	NNP
cord-313312-h607itv2	251	119	,	,	,
cord-313312-h607itv2	251	120	type-26	type-26	CD
cord-313312-h607itv2	251	121	and	and	CC
cord-313312-h607itv2	251	122	type-36	type-36	IN
cord-313312-h607itv2	251	123	neutralizing	neutralize	VBG
cord-313312-h607itv2	251	124	antibodies	antibody	NNS
cord-313312-h607itv2	251	125	:	:	:
cord-313312-h607itv2	252	1	Correlates	correlate	NNS
cord-313312-h607itv2	252	2	of	of	IN
cord-313312-h607itv2	252	3	high	high	JJ
cord-313312-h607itv2	252	4	Ad5	ad5	CD
cord-313312-h607itv2	252	5	titers	titer	NNS
cord-313312-h607itv2	252	6	and	and	CC
cord-313312-h607itv2	252	7	implications	implication	NNS
cord-313312-h607itv2	252	8	for	for	IN
cord-313312-h607itv2	252	9	potential	potential	JJ
cord-313312-h607itv2	252	10	HIV	HIV	NNP
cord-313312-h607itv2	252	11	vaccine	vaccine	NN
cord-313312-h607itv2	252	12	trials	trial	NNS
cord-313312-h607itv2	252	13	Efficacy	Efficacy	NNP
cord-313312-h607itv2	252	14	assessment	assessment	NN
cord-313312-h607itv2	252	15	of	of	IN
cord-313312-h607itv2	252	16	a	a	DT
cord-313312-h607itv2	252	17	cell	cell	NN
cord-313312-h607itv2	252	18	-	-	HYPH
cord-313312-h607itv2	252	19	mediated	mediate	VBN
cord-313312-h607itv2	252	20	immunity	immunity	NN
cord-313312-h607itv2	252	21	HIV-1	HIV-1	NNP
cord-313312-h607itv2	252	22	vaccine	vaccine	NN
cord-313312-h607itv2	252	23	(	(	-LRB-
cord-313312-h607itv2	252	24	the	the	DT
cord-313312-h607itv2	252	25	Step	Step	NNP
cord-313312-h607itv2	252	26	Study	Study	NNP
cord-313312-h607itv2	252	27	)	)	-RRB-
cord-313312-h607itv2	252	28	:	:	:
cord-313312-h607itv2	252	29	A	a	DT
cord-313312-h607itv2	252	30	double	double	JJ
cord-313312-h607itv2	252	31	-	-	HYPH
cord-313312-h607itv2	252	32	blind	blind	JJ
cord-313312-h607itv2	252	33	,	,	,
cord-313312-h607itv2	252	34	randomised	randomised	JJ
cord-313312-h607itv2	252	35	,	,	,
cord-313312-h607itv2	252	36	placebo	placebo	NN
cord-313312-h607itv2	252	37	-	-	HYPH
cord-313312-h607itv2	252	38	controlled	control	VBN
cord-313312-h607itv2	252	39	,	,	,
cord-313312-h607itv2	252	40	test	test	NN
cord-313312-h607itv2	252	41	-	-	HYPH
cord-313312-h607itv2	252	42	of	of	IN
cord-313312-h607itv2	252	43	-	-	HYPH
cord-313312-h607itv2	252	44	concept	concept	NN
cord-313312-h607itv2	252	45	trial	trial	NN
cord-313312-h607itv2	252	46	Overcoming	overcome	VBG
cord-313312-h607itv2	252	47	immunity	immunity	NN
cord-313312-h607itv2	252	48	to	to	IN
cord-313312-h607itv2	252	49	a	a	DT
cord-313312-h607itv2	252	50	viral	viral	JJ
cord-313312-h607itv2	252	51	vaccine	vaccine	NN
cord-313312-h607itv2	252	52	by	by	IN
cord-313312-h607itv2	252	53	DNA	dna	NN
cord-313312-h607itv2	252	54	priming	priming	NN
cord-313312-h607itv2	252	55	before	before	IN
cord-313312-h607itv2	252	56	vector	vector	NN
cord-313312-h607itv2	252	57	boosting	boost	VBG
cord-313312-h607itv2	252	58	Comparative	comparative	JJ
cord-313312-h607itv2	252	59	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	252	60	in	in	IN
cord-313312-h607itv2	252	61	rhesus	rhesu	NNS
cord-313312-h607itv2	252	62	monkeys	monkey	NNS
cord-313312-h607itv2	252	63	of	of	IN
cord-313312-h607itv2	252	64	DNA	dna	NN
cord-313312-h607itv2	252	65	plasmid	plasmid	NN
cord-313312-h607itv2	252	66	,	,	,
cord-313312-h607itv2	252	67	recombinant	recombinant	JJ
cord-313312-h607itv2	252	68	vaccinia	vaccinia	NN
cord-313312-h607itv2	252	69	virus	virus	NN
cord-313312-h607itv2	252	70	,	,	,
cord-313312-h607itv2	252	71	and	and	CC
cord-313312-h607itv2	252	72	replication	replication	NN
cord-313312-h607itv2	252	73	-	-	HYPH
cord-313312-h607itv2	252	74	defective	defective	JJ
cord-313312-h607itv2	252	75	adenovirus	adenovirus	NN
cord-313312-h607itv2	252	76	vectors	vector	NNS
cord-313312-h607itv2	252	77	expressing	express	VBG
cord-313312-h607itv2	253	1	a	a	DT
cord-313312-h607itv2	253	2	human	human	JJ
cord-313312-h607itv2	253	3	immunodeficiency	immunodeficiency	NN
cord-313312-h607itv2	253	4	virus	virus	NN
cord-313312-h607itv2	253	5	type	type	NN
cord-313312-h607itv2	253	6	1	1	CD
cord-313312-h607itv2	253	7	gag	gag	NN
cord-313312-h607itv2	253	8	gene	gene	NN
cord-313312-h607itv2	253	9	A	a	DT
cord-313312-h607itv2	253	10	human	human	JJ
cord-313312-h607itv2	253	11	type	type	NN
cord-313312-h607itv2	253	12	5	5	CD
cord-313312-h607itv2	253	13	adenovirus	adenovirus	NN
cord-313312-h607itv2	253	14	-	-	HYPH
cord-313312-h607itv2	253	15	based	base	VBN
cord-313312-h607itv2	253	16	tuberculosis	tuberculosis	NN
cord-313312-h607itv2	253	17	vaccine	vaccine	NN
cord-313312-h607itv2	253	18	induces	induce	VBZ
cord-313312-h607itv2	253	19	robust	robust	JJ
cord-313312-h607itv2	253	20	T	T	NNP
cord-313312-h607itv2	253	21	cell	cell	NN
cord-313312-h607itv2	253	22	responses	response	NNS
cord-313312-h607itv2	253	23	in	in	IN
cord-313312-h607itv2	253	24	humans	human	NNS
cord-313312-h607itv2	253	25	despite	despite	IN
cord-313312-h607itv2	253	26	preexisting	preexist	VBG
cord-313312-h607itv2	253	27	anti	anti	JJ
cord-313312-h607itv2	253	28	-	-	JJ
cord-313312-h607itv2	253	29	adenovirus	adenovirus	JJ
cord-313312-h607itv2	253	30	immunity	immunity	NN
cord-313312-h607itv2	253	31	New	new	JJ
cord-313312-h607itv2	253	32	recombinant	recombinant	JJ
cord-313312-h607itv2	253	33	Ad5	ad5	CD
cord-313312-h607itv2	253	34	vector	vector	NN
cord-313312-h607itv2	253	35	overcomes	overcome	VBZ
cord-313312-h607itv2	253	36	Ad5	Ad5	NNP
cord-313312-h607itv2	253	37	immunity	immunity	NN
cord-313312-h607itv2	253	38	allowing	allow	VBG
cord-313312-h607itv2	253	39	for	for	IN
cord-313312-h607itv2	253	40	multiple	multiple	JJ
cord-313312-h607itv2	253	41	safe	safe	JJ
cord-313312-h607itv2	253	42	,	,	,
cord-313312-h607itv2	253	43	homologous	homologous	JJ
cord-313312-h607itv2	253	44	immunizations	immunization	NNS
cord-313312-h607itv2	253	45	Hexon	Hexon	NNP
cord-313312-h607itv2	253	46	-	-	HYPH
cord-313312-h607itv2	253	47	chimaeric	chimaeric	JJ
cord-313312-h607itv2	253	48	adenovirus	adenovirus	NN
cord-313312-h607itv2	253	49	serotype	serotype	NN
cord-313312-h607itv2	253	50	5	5	CD
cord-313312-h607itv2	253	51	vectors	vector	NNS
cord-313312-h607itv2	253	52	circumvent	circumvent	VBP
cord-313312-h607itv2	253	53	pre	pre	JJ
cord-313312-h607itv2	253	54	-	-	JJ
cord-313312-h607itv2	253	55	existing	existing	JJ
cord-313312-h607itv2	253	56	anti	anti	JJ
cord-313312-h607itv2	253	57	-	-	JJ
cord-313312-h607itv2	253	58	vector	vector	JJ
cord-313312-h607itv2	253	59	immunity	immunity	NN
cord-313312-h607itv2	253	60	Extensive	extensive	JJ
cord-313312-h607itv2	253	61	cross	cross	NN
cord-313312-h607itv2	253	62	-	-	NN
cord-313312-h607itv2	253	63	reactivity	reactivity	NN
cord-313312-h607itv2	253	64	of	of	IN
cord-313312-h607itv2	253	65	CD4	CD4	NNP
cord-313312-h607itv2	253	66	+	+	CC
cord-313312-h607itv2	253	67	adenovirus	adenovirus	NN
cord-313312-h607itv2	253	68	-	-	HYPH
cord-313312-h607itv2	253	69	specific	specific	JJ
cord-313312-h607itv2	253	70	T	t	NN
cord-313312-h607itv2	253	71	cells	cell	NNS
cord-313312-h607itv2	253	72	:	:	:
cord-313312-h607itv2	253	73	Implications	implication	NNS
cord-313312-h607itv2	253	74	for	for	IN
cord-313312-h607itv2	253	75	immunotherapy	immunotherapy	NN
cord-313312-h607itv2	253	76	and	and	CC
cord-313312-h607itv2	253	77	gene	gene	NN
cord-313312-h607itv2	253	78	therapy	therapy	NN
cord-313312-h607itv2	253	79	Immunogenicity	Immunogenicity	NNP
cord-313312-h607itv2	253	80	of	of	IN
cord-313312-h607itv2	253	81	recombinant	recombinant	JJ
cord-313312-h607itv2	253	82	adenovirus	adenovirus	NN
cord-313312-h607itv2	253	83	serotype	serotype	NN
cord-313312-h607itv2	253	84	35	35	CD
cord-313312-h607itv2	253	85	vaccine	vaccine	NN
cord-313312-h607itv2	253	86	in	in	IN
cord-313312-h607itv2	253	87	the	the	DT
cord-313312-h607itv2	253	88	presence	presence	NN
cord-313312-h607itv2	253	89	of	of	IN
cord-313312-h607itv2	253	90	pre	pre	JJ
cord-313312-h607itv2	253	91	-	-	JJ
cord-313312-h607itv2	253	92	existing	existing	JJ
cord-313312-h607itv2	253	93	anti	anti	JJ
cord-313312-h607itv2	253	94	-	-	JJ
cord-313312-h607itv2	253	95	Ad5	ad5	JJ
cord-313312-h607itv2	253	96	immunity	immunity	NN
cord-313312-h607itv2	253	97	Immunogenicity	Immunogenicity	NNP
cord-313312-h607itv2	253	98	of	of	IN
cord-313312-h607itv2	253	99	heterologous	heterologous	JJ
cord-313312-h607itv2	253	100	prime	prime	JJ
cord-313312-h607itv2	253	101	-	-	HYPH
cord-313312-h607itv2	253	102	boost	boost	NN
cord-313312-h607itv2	253	103	regimens	regimen	NNS
cord-313312-h607itv2	253	104	involving	involve	VBG
cord-313312-h607itv2	253	105	recombinant	recombinant	JJ
cord-313312-h607itv2	253	106	adenovirus	adenovirus	NN
cord-313312-h607itv2	253	107	serotype	serotype	NN
cord-313312-h607itv2	253	108	11	11	CD
cord-313312-h607itv2	253	109	(	(	-LRB-
cord-313312-h607itv2	253	110	Ad11	Ad11	NNP
cord-313312-h607itv2	253	111	)	)	-RRB-
cord-313312-h607itv2	253	112	and	and	CC
cord-313312-h607itv2	253	113	Ad35	Ad35	NNP
cord-313312-h607itv2	254	1	vaccine	vaccine	NN
cord-313312-h607itv2	254	2	vectors	vector	NNS
cord-313312-h607itv2	254	3	in	in	IN
cord-313312-h607itv2	254	4	the	the	DT
cord-313312-h607itv2	254	5	presence	presence	NN
cord-313312-h607itv2	254	6	of	of	IN
cord-313312-h607itv2	254	7	anti	anti	JJ
cord-313312-h607itv2	254	8	-	-	JJ
cord-313312-h607itv2	254	9	ad5	ad5	JJ
cord-313312-h607itv2	254	10	immunity	immunity	NN
cord-313312-h607itv2	254	11	Estimates	estimate	NNS
cord-313312-h607itv2	254	12	of	of	IN
cord-313312-h607itv2	254	13	global	global	JJ
cord-313312-h607itv2	254	14	seasonal	seasonal	JJ
cord-313312-h607itv2	254	15	influenza	influenza	NN
cord-313312-h607itv2	254	16	-	-	HYPH
cord-313312-h607itv2	254	17	associated	associate	VBN
cord-313312-h607itv2	254	18	respiratory	respiratory	JJ
cord-313312-h607itv2	254	19	mortality	mortality	NN
cord-313312-h607itv2	254	20	:	:	:
cord-313312-h607itv2	254	21	A	a	DT
cord-313312-h607itv2	254	22	modelling	modelling	NN
cord-313312-h607itv2	254	23	study	study	NN
cord-313312-h607itv2	254	24	Prevention	Prevention	NNP
cord-313312-h607itv2	254	25	and	and	CC
cord-313312-h607itv2	254	26	Control	Control	NNP
cord-313312-h607itv2	254	27	of	of	IN
cord-313312-h607itv2	254	28	Seasonal	Seasonal	NNP
cord-313312-h607itv2	254	29	Influenza	Influenza	NNP
cord-313312-h607itv2	254	30	with	with	IN
cord-313312-h607itv2	254	31	Vaccines	vaccine	NNS
cord-313312-h607itv2	254	32	:	:	:
cord-313312-h607itv2	254	33	Recommendations	recommendation	NNS
cord-313312-h607itv2	254	34	of	of	IN
cord-313312-h607itv2	254	35	the	the	DT
cord-313312-h607itv2	254	36	Advisory	Advisory	NNP
cord-313312-h607itv2	254	37	Committee	Committee	NNP
cord-313312-h607itv2	254	38	on	on	IN
cord-313312-h607itv2	254	39	Immunization	Immunization	NNP
cord-313312-h607itv2	254	40	Practices	Practices	NNPS
cord-313312-h607itv2	254	41	-United	-unite	VBD
cord-313312-h607itv2	254	42	States	States	NNP
cord-313312-h607itv2	254	43	,	,	,
cord-313312-h607itv2	254	44	2019	2019	CD
cord-313312-h607itv2	254	45	-	-	SYM
cord-313312-h607itv2	254	46	20	20	CD
cord-313312-h607itv2	255	1	Influenza	Influenza	NNP
cord-313312-h607itv2	255	2	Season	Season	NNP
cord-313312-h607itv2	255	3	Influenza	Influenza	NNP
cord-313312-h607itv2	255	4	vaccines	vaccine	NNS
cord-313312-h607itv2	255	5	:	:	:
cord-313312-h607itv2	255	6	Challenges	challenge	NNS
cord-313312-h607itv2	255	7	and	and	CC
cord-313312-h607itv2	255	8	solutions	solution	NNS
cord-313312-h607itv2	256	1	The	the	DT
cord-313312-h607itv2	256	2	role	role	NN
cord-313312-h607itv2	256	3	of	of	IN
cord-313312-h607itv2	256	4	nasal	nasal	NN
cord-313312-h607itv2	256	5	IgA	IgA	NNP
cord-313312-h607itv2	256	6	in	in	IN
cord-313312-h607itv2	256	7	children	child	NNS
cord-313312-h607itv2	256	8	vaccinated	vaccinate	VBN
cord-313312-h607itv2	256	9	with	with	IN
cord-313312-h607itv2	256	10	live	live	JJ
cord-313312-h607itv2	256	11	attenuated	attenuated	JJ
cord-313312-h607itv2	256	12	influenza	influenza	NN
cord-313312-h607itv2	256	13	vaccine	vaccine	NN
cord-313312-h607itv2	256	14	Correlation	Correlation	NNP
cord-313312-h607itv2	256	15	of	of	IN
cord-313312-h607itv2	256	16	Cellular	Cellular	NNP
cord-313312-h607itv2	256	17	Immune	Immune	NNP
cord-313312-h607itv2	256	18	Responses	Responses	NNPS
cord-313312-h607itv2	256	19	with	with	IN
cord-313312-h607itv2	256	20	Protection	Protection	NNP
cord-313312-h607itv2	256	21	against	against	IN
cord-313312-h607itv2	256	22	Culture	Culture	NNP
cord-313312-h607itv2	256	23	-	-	HYPH
cord-313312-h607itv2	256	24	Confirmed	confirm	VBN
cord-313312-h607itv2	256	25	Influenza	Influenza	NNP
cord-313312-h607itv2	256	26	Virus	Virus	NNP
cord-313312-h607itv2	256	27	in	in	IN
cord-313312-h607itv2	256	28	Young	Young	NNP
cord-313312-h607itv2	256	29	Children	child	NNS
cord-313312-h607itv2	257	1	The	the	DT
cord-313312-h607itv2	257	2	efficacy	efficacy	NN
cord-313312-h607itv2	257	3	of	of	IN
cord-313312-h607itv2	257	4	intranasal	intranasal	NN
cord-313312-h607itv2	257	5	live	live	NN
cord-313312-h607itv2	257	6	attenuated	attenuated	JJ
cord-313312-h607itv2	257	7	influenza	influenza	NN
cord-313312-h607itv2	257	8	vaccine	vaccine	NN
cord-313312-h607itv2	257	9	in	in	IN
cord-313312-h607itv2	257	10	children	child	NNS
cord-313312-h607itv2	257	11	2	2	CD
cord-313312-h607itv2	257	12	through	through	IN
cord-313312-h607itv2	257	13	17	17	CD
cord-313312-h607itv2	257	14	years	year	NNS
cord-313312-h607itv2	257	15	of	of	IN
cord-313312-h607itv2	257	16	age	age	NN
cord-313312-h607itv2	257	17	:	:	:
cord-313312-h607itv2	258	1	A	a	DT
cord-313312-h607itv2	258	2	meta	meta	JJ
cord-313312-h607itv2	258	3	-	-	HYPH
cord-313312-h607itv2	258	4	analysis	analysis	NN
cord-313312-h607itv2	258	5	of	of	IN
cord-313312-h607itv2	258	6	8	8	CD
cord-313312-h607itv2	258	7	randomized	randomized	JJ
cord-313312-h607itv2	258	8	controlled	control	VBN
cord-313312-h607itv2	258	9	studies	study	NNS
cord-313312-h607itv2	259	1	The	the	DT
cord-313312-h607itv2	259	2	Effect	effect	NN
cord-313312-h607itv2	259	3	of	of	IN
cord-313312-h607itv2	259	4	Preexisting	Preexisting	NNP
cord-313312-h607itv2	259	5	Immunity	Immunity	NNP
cord-313312-h607itv2	259	6	on	on	IN
cord-313312-h607itv2	259	7	Virus	Virus	NNP
cord-313312-h607itv2	259	8	Detection	Detection	NNP
cord-313312-h607itv2	259	9	and	and	CC
cord-313312-h607itv2	259	10	Immune	Immune	NNP
cord-313312-h607itv2	259	11	Responses	response	NNS
cord-313312-h607itv2	259	12	in	in	IN
cord-313312-h607itv2	259	13	a	a	DT
cord-313312-h607itv2	259	14	Phase	Phase	NNP
cord-313312-h607itv2	259	15	II	II	NNP
cord-313312-h607itv2	259	16	,	,	,
cord-313312-h607itv2	259	17	Randomized	Randomized	NNP
cord-313312-h607itv2	259	18	Trial	Trial	NNP
cord-313312-h607itv2	259	19	of	of	IN
cord-313312-h607itv2	259	20	a	a	DT
cord-313312-h607itv2	259	21	Russian	Russian	NNP
cord-313312-h607itv2	259	22	-	-	HYPH
cord-313312-h607itv2	259	23	Backbone	backbone	NN
cord-313312-h607itv2	259	24	,	,	,
cord-313312-h607itv2	259	25	Live	live	JJ
cord-313312-h607itv2	259	26	,	,	,
cord-313312-h607itv2	259	27	Attenuated	Attenuated	NNP
cord-313312-h607itv2	259	28	Influenza	Influenza	NNP
cord-313312-h607itv2	259	29	Vaccine	Vaccine	NNP
cord-313312-h607itv2	259	30	in	in	IN
cord-313312-h607itv2	259	31	Bangladeshi	bangladeshi	JJ
cord-313312-h607itv2	259	32	Children	Children	NNP
cord-313312-h607itv2	259	33	Longevity	Longevity	NNP
cord-313312-h607itv2	259	34	of	of	IN
cord-313312-h607itv2	259	35	B	b	NN
cord-313312-h607itv2	259	36	-	-	HYPH
cord-313312-h607itv2	259	37	cell	cell	NN
cord-313312-h607itv2	259	38	and	and	CC
cord-313312-h607itv2	259	39	T	t	NN
cord-313312-h607itv2	259	40	-	-	HYPH
cord-313312-h607itv2	259	41	cell	cell	NN
cord-313312-h607itv2	259	42	responses	response	NNS
cord-313312-h607itv2	259	43	after	after	IN
cord-313312-h607itv2	259	44	live	live	JJ
cord-313312-h607itv2	259	45	attenuated	attenuated	JJ
cord-313312-h607itv2	259	46	influenza	influenza	NN
cord-313312-h607itv2	259	47	vaccination	vaccination	NN
cord-313312-h607itv2	259	48	in	in	IN
cord-313312-h607itv2	259	49	children	child	NNS
cord-313312-h607itv2	259	50	Boosting	boost	VBG
cord-313312-h607itv2	259	51	of	of	IN
cord-313312-h607itv2	259	52	Cross	Cross	NNP
cord-313312-h607itv2	259	53	-	-	HYPH
cord-313312-h607itv2	259	54	Reactive	Reactive	NNP
cord-313312-h607itv2	259	55	and	and	CC
cord-313312-h607itv2	259	56	Protection	Protection	NNP
cord-313312-h607itv2	259	57	-	-	HYPH
cord-313312-h607itv2	259	58	Associated	Associated	NNP
cord-313312-h607itv2	259	59	T	T	NNP
cord-313312-h607itv2	259	60	Cells	cell	NNS
cord-313312-h607itv2	259	61	in	in	IN
cord-313312-h607itv2	259	62	Children	child	NNS
cord-313312-h607itv2	260	1	After	after	IN
cord-313312-h607itv2	260	2	Live	live	JJ
cord-313312-h607itv2	260	3	Attenuated	Attenuated	NNP
cord-313312-h607itv2	260	4	Influenza	Influenza	NNP
cord-313312-h607itv2	260	5	Vaccination	Vaccination	NNP
cord-313312-h607itv2	260	6	Evaluation	Evaluation	NNP
cord-313312-h607itv2	260	7	of	of	IN
cord-313312-h607itv2	260	8	bivalent	bivalent	NN
cord-313312-h607itv2	261	1	live	live	VB
cord-313312-h607itv2	261	2	attenuated	attenuated	JJ
cord-313312-h607itv2	261	3	influenza	influenza	NN
cord-313312-h607itv2	261	4	A	a	DT
cord-313312-h607itv2	261	5	vaccines	vaccine	NNS
cord-313312-h607itv2	261	6	in	in	IN
cord-313312-h607itv2	261	7	children	child	NNS
cord-313312-h607itv2	261	8	2	2	CD
cord-313312-h607itv2	261	9	months	month	NNS
cord-313312-h607itv2	261	10	to	to	IN
cord-313312-h607itv2	261	11	3	3	CD
cord-313312-h607itv2	261	12	years	year	NNS
cord-313312-h607itv2	261	13	of	of	IN
cord-313312-h607itv2	261	14	age	age	NN
cord-313312-h607itv2	261	15	:	:	:
cord-313312-h607itv2	261	16	Safety	safety	NN
cord-313312-h607itv2	261	17	,	,	,
cord-313312-h607itv2	261	18	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	261	19	and	and	CC
cord-313312-h607itv2	261	20	dose	dose	NN
cord-313312-h607itv2	261	21	-	-	HYPH
cord-313312-h607itv2	261	22	response	response	NN
cord-313312-h607itv2	261	23	Negative	negative	JJ
cord-313312-h607itv2	261	24	impact	impact	NN
cord-313312-h607itv2	261	25	of	of	IN
cord-313312-h607itv2	261	26	prior	prior	JJ
cord-313312-h607itv2	261	27	influenza	influenza	NN
cord-313312-h607itv2	261	28	vaccination	vaccination	NN
cord-313312-h607itv2	261	29	on	on	IN
cord-313312-h607itv2	261	30	current	current	JJ
cord-313312-h607itv2	261	31	influenza	influenza	NN
cord-313312-h607itv2	261	32	vaccination	vaccination	NN
cord-313312-h607itv2	261	33	among	among	IN
cord-313312-h607itv2	261	34	people	people	NNS
cord-313312-h607itv2	261	35	infected	infect	VBN
cord-313312-h607itv2	261	36	and	and	CC
cord-313312-h607itv2	261	37	not	not	RB
cord-313312-h607itv2	261	38	infected	infect	VBN
cord-313312-h607itv2	261	39	in	in	IN
cord-313312-h607itv2	261	40	prior	prior	JJ
cord-313312-h607itv2	261	41	season	season	NN
cord-313312-h607itv2	261	42	:	:	:
cord-313312-h607itv2	262	1	A	a	DT
cord-313312-h607itv2	262	2	test	test	NN
cord-313312-h607itv2	262	3	-	-	HYPH
cord-313312-h607itv2	262	4	negative	negative	JJ
cord-313312-h607itv2	262	5	case	case	NN
cord-313312-h607itv2	262	6	-	-	HYPH
cord-313312-h607itv2	262	7	control	control	NN
cord-313312-h607itv2	262	8	study	study	NN
cord-313312-h607itv2	262	9	in	in	IN
cord-313312-h607itv2	262	10	Japan	Japan	NNP
cord-313312-h607itv2	262	11	Influence	Influence	NNP
cord-313312-h607itv2	262	12	of	of	IN
cord-313312-h607itv2	262	13	prior	prior	JJ
cord-313312-h607itv2	262	14	influenza	influenza	NN
cord-313312-h607itv2	262	15	vaccination	vaccination	NN
cord-313312-h607itv2	262	16	on	on	IN
cord-313312-h607itv2	262	17	antibody	antibody	NN
cord-313312-h607itv2	262	18	and	and	CC
cord-313312-h607itv2	262	19	B	b	NN
cord-313312-h607itv2	262	20	-	-	HYPH
cord-313312-h607itv2	262	21	cell	cell	NN
cord-313312-h607itv2	262	22	responses	response	NNS
cord-313312-h607itv2	262	23	Development	Development	NNP
cord-313312-h607itv2	262	24	of	of	IN
cord-313312-h607itv2	262	25	live	live	JJ
cord-313312-h607itv2	262	26	attenuated	attenuated	JJ
cord-313312-h607itv2	262	27	influenza	influenza	NN
cord-313312-h607itv2	262	28	vaccines	vaccine	NNS
cord-313312-h607itv2	262	29	against	against	IN
cord-313312-h607itv2	262	30	pandemic	pandemic	NN
cord-313312-h607itv2	262	31	influenza	influenza	NN
cord-313312-h607itv2	262	32	strains	strain	NNS
cord-313312-h607itv2	263	1	An	an	DT
cord-313312-h607itv2	263	2	integrated	integrated	JJ
cord-313312-h607itv2	263	3	multi	multi	JJ
cord-313312-h607itv2	263	4	-	-	JJ
cord-313312-h607itv2	263	5	study	study	JJ
cord-313312-h607itv2	263	6	analysis	analysis	NN
cord-313312-h607itv2	263	7	of	of	IN
cord-313312-h607itv2	263	8	serum	serum	NN
cord-313312-h607itv2	263	9	HAI	HAI	NNP
cord-313312-h607itv2	263	10	antibody	antibody	NN
cord-313312-h607itv2	263	11	responses	response	NNS
cord-313312-h607itv2	263	12	to	to	IN
cord-313312-h607itv2	263	13	Ann	Ann	NNP
cord-313312-h607itv2	263	14	Arbor	Arbor	NNP
cord-313312-h607itv2	263	15	strain	strain	VB
cord-313312-h607itv2	263	16	live	live	RB
cord-313312-h607itv2	263	17	attenuated	attenuated	JJ
cord-313312-h607itv2	263	18	influenza	influenza	NN
cord-313312-h607itv2	263	19	vaccine	vaccine	NN
cord-313312-h607itv2	263	20	in	in	IN
cord-313312-h607itv2	263	21	children	child	NNS
cord-313312-h607itv2	263	22	and	and	CC
cord-313312-h607itv2	263	23	adults	adult	NNS
cord-313312-h607itv2	264	1	A	a	DT
cord-313312-h607itv2	264	2	structural	structural	JJ
cord-313312-h607itv2	264	3	perspective	perspective	NN
cord-313312-h607itv2	264	4	of	of	IN
cord-313312-h607itv2	264	5	the	the	DT
cord-313312-h607itv2	264	6	flavivirus	flavivirus	NNP
cord-313312-h607itv2	264	7	life	life	NN
cord-313312-h607itv2	264	8	cycle	cycle	NN
cord-313312-h607itv2	264	9	Zika	Zika	NNP
cord-313312-h607itv2	264	10	Virus	Virus	NNP
cord-313312-h607itv2	264	11	Infection	infection	NN
cord-313312-h607itv2	264	12	-	-	:
cord-313312-h607itv2	264	13	After	after	IN
cord-313312-h607itv2	264	14	the	the	DT
cord-313312-h607itv2	264	15	Pandemic	Pandemic	NNP
cord-313312-h607itv2	264	16	The	the	DT
cord-313312-h607itv2	264	17	global	global	JJ
cord-313312-h607itv2	264	18	distribution	distribution	NN
cord-313312-h607itv2	264	19	and	and	CC
cord-313312-h607itv2	264	20	burden	burden	NN
cord-313312-h607itv2	264	21	of	of	IN
cord-313312-h607itv2	264	22	dengue	dengue	NN
cord-313312-h607itv2	264	23	Antigenic	antigenic	JJ
cord-313312-h607itv2	264	24	relationships	relationship	NNS
cord-313312-h607itv2	264	25	between	between	IN
cord-313312-h607itv2	264	26	flaviviruses	flavivirus	NNS
cord-313312-h607itv2	264	27	as	as	IN
cord-313312-h607itv2	264	28	determined	determine	VBN
cord-313312-h607itv2	264	29	by	by	IN
cord-313312-h607itv2	264	30	cross	cross	NN
cord-313312-h607itv2	264	31	-	-	JJ
cord-313312-h607itv2	264	32	neutralization	neutralization	JJ
cord-313312-h607itv2	264	33	tests	test	NNS
cord-313312-h607itv2	264	34	with	with	IN
cord-313312-h607itv2	264	35	polyclonal	polyclonal	JJ
cord-313312-h607itv2	264	36	antisera	antisera	NNP
cord-313312-h607itv2	264	37	Cross	Cross	NNP
cord-313312-h607itv2	264	38	-	-	HYPH
cord-313312-h607itv2	264	39	Reactive	reactive	JJ
cord-313312-h607itv2	264	40	Immunity	immunity	NN
cord-313312-h607itv2	264	41	Among	among	IN
cord-313312-h607itv2	264	42	Flaviviruses	Flaviviruses	NNP
cord-313312-h607itv2	264	43	.	.	.
cord-313312-h607itv2	265	1	Front	front	NN
cord-313312-h607itv2	265	2	.	.	.
cord-313312-h607itv2	266	1	Immunol	Immunol	NNP
cord-313312-h607itv2	266	2	.	.	.
cord-313312-h607itv2	267	1	2020	2020	CD
cord-313312-h607itv2	267	2	,	,	,
cord-313312-h607itv2	267	3	11	11	CD
cord-313312-h607itv2	267	4	Review	Review	NNP
cord-313312-h607itv2	267	5	article	article	NN
cord-313312-h607itv2	267	6	:	:	:
cord-313312-h607itv2	268	1	Research	research	NN
cord-313312-h607itv2	268	2	on	on	IN
cord-313312-h607itv2	268	3	dengue	dengue	NN
cord-313312-h607itv2	268	4	during	during	IN
cord-313312-h607itv2	268	5	World	World	NNP
cord-313312-h607itv2	268	6	War	War	NNP
cord-313312-h607itv2	268	7	II	II	NNP
cord-313312-h607itv2	268	8	revisited	revisit	VBD
cord-313312-h607itv2	268	9	Research	Research	NNP
cord-313312-h607itv2	268	10	on	on	IN
cord-313312-h607itv2	268	11	dengue	dengue	NN
cord-313312-h607itv2	268	12	during	during	IN
cord-313312-h607itv2	268	13	World	World	NNP
cord-313312-h607itv2	268	14	War	War	NNP
cord-313312-h607itv2	268	15	II	II	NNP
cord-313312-h607itv2	268	16	Epidemiologic	Epidemiologic	NNP
cord-313312-h607itv2	268	17	Studies	Studies	NNPS
cord-313312-h607itv2	268	18	on	on	IN
cord-313312-h607itv2	268	19	Dengue	Dengue	NNP
cord-313312-h607itv2	268	20	in	in	IN
cord-313312-h607itv2	268	21	Santiago	Santiago	NNP
cord-313312-h607itv2	268	22	de	de	NNP
cord-313312-h607itv2	268	23	Cuba	Cuba	NNP
cord-313312-h607itv2	268	24	Antibody	Antibody	NNP
cord-313312-h607itv2	268	25	-	-	HYPH
cord-313312-h607itv2	268	26	dependent	dependent	JJ
cord-313312-h607itv2	268	27	enhancement	enhancement	NN
cord-313312-h607itv2	268	28	of	of	IN
cord-313312-h607itv2	268	29	severe	severe	JJ
cord-313312-h607itv2	268	30	dengue	dengue	NN
cord-313312-h607itv2	268	31	disease	disease	NN
cord-313312-h607itv2	268	32	in	in	IN
cord-313312-h607itv2	268	33	humans	human	NNS
cord-313312-h607itv2	268	34	Reconstruction	Reconstruction	NNP
cord-313312-h607itv2	268	35	of	of	IN
cord-313312-h607itv2	268	36	antibody	antibody	NN
cord-313312-h607itv2	268	37	dynamics	dynamic	NNS
cord-313312-h607itv2	268	38	and	and	CC
cord-313312-h607itv2	268	39	infection	infection	NN
cord-313312-h607itv2	268	40	histories	history	NNS
cord-313312-h607itv2	268	41	to	to	TO
cord-313312-h607itv2	268	42	evaluate	evaluate	VB
cord-313312-h607itv2	268	43	dengue	dengue	NN
cord-313312-h607itv2	269	1	risk	risk	NN
cord-313312-h607itv2	269	2	Evidence	evidence	NN
cord-313312-h607itv2	269	3	that	that	IN
cord-313312-h607itv2	269	4	maternal	maternal	JJ
cord-313312-h607itv2	269	5	dengue	dengue	NN
cord-313312-h607itv2	269	6	antibodies	antibody	NNS
cord-313312-h607itv2	269	7	are	be	VBP
cord-313312-h607itv2	269	8	important	important	JJ
cord-313312-h607itv2	269	9	in	in	IN
cord-313312-h607itv2	269	10	the	the	DT
cord-313312-h607itv2	269	11	development	development	NN
cord-313312-h607itv2	269	12	of	of	IN
cord-313312-h607itv2	269	13	dengue	dengue	NN
cord-313312-h607itv2	269	14	hemorrhagic	hemorrhagic	JJ
cord-313312-h607itv2	269	15	fever	fever	NN
cord-313312-h607itv2	269	16	in	in	IN
cord-313312-h607itv2	269	17	infants	infant	NNS
cord-313312-h607itv2	269	18	Efficacy	Efficacy	NNP
cord-313312-h607itv2	269	19	of	of	IN
cord-313312-h607itv2	269	20	a	a	DT
cord-313312-h607itv2	269	21	tetravalent	tetravalent	NN
cord-313312-h607itv2	269	22	dengue	dengue	NN
cord-313312-h607itv2	269	23	vaccine	vaccine	NN
cord-313312-h607itv2	269	24	in	in	IN
cord-313312-h607itv2	269	25	children	child	NNS
cord-313312-h607itv2	269	26	in	in	IN
cord-313312-h607itv2	269	27	Latin	Latin	NNP
cord-313312-h607itv2	269	28	America	America	NNP
cord-313312-h607itv2	269	29	Efficacy	Efficacy	NNP
cord-313312-h607itv2	269	30	of	of	IN
cord-313312-h607itv2	269	31	a	a	DT
cord-313312-h607itv2	269	32	Tetravalent	Tetravalent	NNP
cord-313312-h607itv2	269	33	Dengue	Dengue	NNP
cord-313312-h607itv2	269	34	Vaccine	Vaccine	NNP
cord-313312-h607itv2	269	35	in	in	IN
cord-313312-h607itv2	269	36	Healthy	Healthy	NNP
cord-313312-h607itv2	269	37	Children	Children	NNPS
cord-313312-h607itv2	269	38	and	and	CC
cord-313312-h607itv2	269	39	Adolescents	Adolescents	NNPS
cord-313312-h607itv2	270	1	Flavivirus	Flavivirus	NNP
cord-313312-h607itv2	270	2	serocomplex	serocomplex	NNP
cord-313312-h607itv2	270	3	cross	cross	JJ
cord-313312-h607itv2	270	4	-	-	JJ
cord-313312-h607itv2	270	5	reactive	reactive	JJ
cord-313312-h607itv2	270	6	immunity	immunity	NN
cord-313312-h607itv2	270	7	is	be	VBZ
cord-313312-h607itv2	270	8	protective	protective	JJ
cord-313312-h607itv2	270	9	by	by	IN
cord-313312-h607itv2	270	10	activating	activate	VBG
cord-313312-h607itv2	270	11	heterologous	heterologous	JJ
cord-313312-h607itv2	270	12	memory	memory	NN
cord-313312-h607itv2	270	13	CD4	CD4	NNP
cord-313312-h607itv2	270	14	T	T	NNP
cord-313312-h607itv2	270	15	cells	cell	NNS
cord-313312-h607itv2	270	16	Pre	pre	JJ
cord-313312-h607itv2	270	17	-	-	JJ
cord-313312-h607itv2	270	18	existing	exist	VBG
cord-313312-h607itv2	270	19	yellow	yellow	JJ
cord-313312-h607itv2	270	20	fever	fever	NN
cord-313312-h607itv2	270	21	immunity	immunity	NN
cord-313312-h607itv2	270	22	impairs	impair	VBZ
cord-313312-h607itv2	270	23	and	and	CC
cord-313312-h607itv2	270	24	modulates	modulate	VBZ
cord-313312-h607itv2	270	25	the	the	DT
cord-313312-h607itv2	270	26	antibody	antibody	NN
cord-313312-h607itv2	270	27	response	response	NN
cord-313312-h607itv2	270	28	to	to	TO
cord-313312-h607itv2	270	29	tick	tick	VB
cord-313312-h607itv2	270	30	-	-	HYPH
cord-313312-h607itv2	270	31	borne	bear	VBN
cord-313312-h607itv2	270	32	encephalitis	encephalitis	JJ
cord-313312-h607itv2	270	33	vaccination	vaccination	NN
cord-313312-h607itv2	270	34	Cross	Cross	NNP
cord-313312-h607itv2	270	35	-	-	JJ
cord-313312-h607itv2	270	36	reactive	reactive	JJ
cord-313312-h607itv2	270	37	antibodies	antibody	NNS
cord-313312-h607itv2	270	38	enhance	enhance	VBP
cord-313312-h607itv2	270	39	live	live	JJ
cord-313312-h607itv2	270	40	attenuated	attenuated	JJ
cord-313312-h607itv2	270	41	virus	virus	NN
cord-313312-h607itv2	270	42	infection	infection	NN
cord-313312-h607itv2	270	43	for	for	IN
cord-313312-h607itv2	270	44	increased	increase	VBN
cord-313312-h607itv2	270	45	immunogenicity	immunogenicity	NN
cord-313312-h607itv2	270	46	IgG	IgG	NNP
cord-313312-h607itv2	270	47	Fc	Fc	NNP
cord-313312-h607itv2	270	48	Receptors	Receptors	NNP
cord-313312-h607itv2	270	49	Physical	Physical	NNP
cord-313312-h607itv2	270	50	and	and	CC
cord-313312-h607itv2	270	51	functional	functional	JJ
cord-313312-h607itv2	270	52	association	association	NN
cord-313312-h607itv2	270	53	of	of	IN
cord-313312-h607itv2	270	54	Src	Src	NNP
cord-313312-h607itv2	270	55	-	-	HYPH
cord-313312-h607itv2	270	56	related	relate	VBN
cord-313312-h607itv2	270	57	protein	protein	NN
cord-313312-h607itv2	270	58	tyrosine	tyrosine	NN
cord-313312-h607itv2	270	59	kinases	kinase	NNS
cord-313312-h607itv2	270	60	with	with	IN
cord-313312-h607itv2	270	61	Fc	Fc	NNP
cord-313312-h607itv2	270	62	gamma	gamma	NN
cord-313312-h607itv2	270	63	RII	RII	NNP
cord-313312-h607itv2	270	64	in	in	IN
cord-313312-h607itv2	270	65	monocytic	monocytic	NNP
cord-313312-h607itv2	270	66	THP-1	THP-1	NNP
cord-313312-h607itv2	270	67	cells	cell	NNS
cord-313312-h607itv2	271	1	A	a	DT
cord-313312-h607itv2	271	2	critical	critical	JJ
cord-313312-h607itv2	271	3	role	role	NN
cord-313312-h607itv2	271	4	for	for	IN
cord-313312-h607itv2	271	5	Syk	Syk	NNP
cord-313312-h607itv2	271	6	in	in	IN
cord-313312-h607itv2	271	7	signal	signal	NN
cord-313312-h607itv2	271	8	transduction	transduction	NN
cord-313312-h607itv2	271	9	and	and	CC
cord-313312-h607itv2	271	10	phagocytosis	phagocytosis	NN
cord-313312-h607itv2	271	11	mediated	mediate	VBN
cord-313312-h607itv2	271	12	by	by	IN
cord-313312-h607itv2	271	13	Fcgamma	Fcgamma	NNP
cord-313312-h607itv2	271	14	receptors	receptor	NNS
cord-313312-h607itv2	271	15	on	on	IN
cord-313312-h607itv2	271	16	macrophages	macrophage	NNS
cord-313312-h607itv2	271	17	FcγRIIb	FcγRIIb	NNP
cord-313312-h607itv2	271	18	controls	control	VBZ
cord-313312-h607itv2	271	19	bone	bone	NN
cord-313312-h607itv2	271	20	marrow	marrow	NN
cord-313312-h607itv2	271	21	plasma	plasma	NN
cord-313312-h607itv2	271	22	cell	cell	NN
cord-313312-h607itv2	271	23	persistence	persistence	NN
cord-313312-h607itv2	271	24	and	and	CC
cord-313312-h607itv2	271	25	apoptosis	apoptosis	NN
cord-313312-h607itv2	271	26	Selective	selective	JJ
cord-313312-h607itv2	271	27	dysregulation	dysregulation	NN
cord-313312-h607itv2	271	28	of	of	IN
cord-313312-h607itv2	271	29	the	the	DT
cord-313312-h607itv2	271	30	FcγIIB	FcγIIB	NNP
cord-313312-h607itv2	271	31	receptor	receptor	NN
cord-313312-h607itv2	271	32	on	on	IN
cord-313312-h607itv2	271	33	memory	memory	NN
cord-313312-h607itv2	271	34	B	b	NN
cord-313312-h607itv2	271	35	cells	cell	NNS
cord-313312-h607itv2	271	36	in	in	IN
cord-313312-h607itv2	271	37	SLE	SLE	NNP
cord-313312-h607itv2	271	38	FcγRIIB	fcγriib	NN
cord-313312-h607itv2	271	39	in	in	IN
cord-313312-h607itv2	271	40	autoimmunity	autoimmunity	NN
cord-313312-h607itv2	271	41	and	and	CC
cord-313312-h607itv2	271	42	infection	infection	NN
cord-313312-h607itv2	271	43	:	:	:
cord-313312-h607itv2	272	1	Evolutionary	evolutionary	JJ
cord-313312-h607itv2	272	2	and	and	CC
cord-313312-h607itv2	272	3	therapeutic	therapeutic	JJ
cord-313312-h607itv2	272	4	implications	implication	NNS
cord-313312-h607itv2	272	5	Dissection	dissection	NN
cord-313312-h607itv2	272	6	of	of	IN
cord-313312-h607itv2	272	7	the	the	DT
cord-313312-h607itv2	272	8	signalling	signal	VBG
cord-313312-h607itv2	272	9	mechanisms	mechanism	NNS
cord-313312-h607itv2	273	1	underlying	underlie	VBG
cord-313312-h607itv2	273	2	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	273	3	-	-	HYPH
cord-313312-h607itv2	273	4	mediated	mediate	VBN
cord-313312-h607itv2	273	5	apoptosis	apoptosis	NN
cord-313312-h607itv2	273	6	of	of	IN
cord-313312-h607itv2	273	7	mature	mature	JJ
cord-313312-h607itv2	273	8	B	b	NN
cord-313312-h607itv2	273	9	-	-	HYPH
cord-313312-h607itv2	273	10	cells	cell	NNS
cord-313312-h607itv2	274	1	The	the	DT
cord-313312-h607itv2	274	2	B	b	NN
cord-313312-h607itv2	274	3	cell	cell	NN
cord-313312-h607itv2	274	4	inhibitory	inhibitory	JJ
cord-313312-h607itv2	274	5	Fc	Fc	NNP
cord-313312-h607itv2	274	6	receptor	receptor	NN
cord-313312-h607itv2	274	7	triggers	trigger	VBZ
cord-313312-h607itv2	274	8	apoptosis	apoptosis	NN
cord-313312-h607itv2	274	9	by	by	IN
cord-313312-h607itv2	274	10	a	a	DT
cord-313312-h607itv2	274	11	novel	novel	NN
cord-313312-h607itv2	274	12	c	c	NN
cord-313312-h607itv2	274	13	-	-	:
cord-313312-h607itv2	274	14	Abl	Abl	NNP
cord-313312-h607itv2	274	15	family	family	NN
cord-313312-h607itv2	274	16	kinase	kinase	NN
cord-313312-h607itv2	274	17	-	-	HYPH
cord-313312-h607itv2	274	18	dependent	dependent	JJ
cord-313312-h607itv2	274	19	pathway	pathway	NN
cord-313312-h607itv2	274	20	Impaired	impair	VBD
cord-313312-h607itv2	274	21	inhibitory	inhibitory	JJ
cord-313312-h607itv2	274	22	Fcγ	Fcγ	NNP
cord-313312-h607itv2	274	23	receptor	receptor	NN
cord-313312-h607itv2	274	24	IIB	IIB	NNP
cord-313312-h607itv2	274	25	expression	expression	NN
cord-313312-h607itv2	274	26	on	on	IN
cord-313312-h607itv2	274	27	B	b	NN
cord-313312-h607itv2	274	28	cells	cell	NNS
cord-313312-h607itv2	274	29	in	in	IN
cord-313312-h607itv2	274	30	chronic	chronic	JJ
cord-313312-h607itv2	274	31	inflammatory	inflammatory	JJ
cord-313312-h607itv2	274	32	demyelinating	demyelinating	NN
cord-313312-h607itv2	274	33	polyneuropathy	polyneuropathy	NNS
cord-313312-h607itv2	275	1	FcγRIIB	FcγRIIB	NNP
cord-313312-h607itv2	275	2	mediates	mediate	VBZ
cord-313312-h607itv2	275	3	antigen	antigen	NN
cord-313312-h607itv2	275	4	-	-	HYPH
cord-313312-h607itv2	275	5	independent	independent	JJ
cord-313312-h607itv2	275	6	inhibition	inhibition	NN
cord-313312-h607itv2	275	7	on	on	IN
cord-313312-h607itv2	275	8	human	human	JJ
cord-313312-h607itv2	275	9	B	b	NN
cord-313312-h607itv2	275	10	lymphocytes	lymphocyte	NNS
cord-313312-h607itv2	275	11	through	through	IN
cord-313312-h607itv2	275	12	Btk	Btk	NNP
cord-313312-h607itv2	275	13	and	and	CC
cord-313312-h607itv2	275	14	p38	p38	NN
cord-313312-h607itv2	275	15	MAPK	MAPK	NNP
cord-313312-h607itv2	275	16	Molecular	Molecular	NNP
cord-313312-h607itv2	275	17	mechanisms	mechanism	NNS
cord-313312-h607itv2	275	18	of	of	IN
cord-313312-h607itv2	275	19	antibody	antibody	NN
cord-313312-h607itv2	275	20	-	-	HYPH
cord-313312-h607itv2	275	21	mediated	mediate	VBN
cord-313312-h607itv2	275	22	neutralisation	neutralisation	NN
cord-313312-h607itv2	275	23	of	of	IN
cord-313312-h607itv2	275	24	flavivirus	flavivirus	JJ
cord-313312-h607itv2	275	25	infection	infection	NN
cord-313312-h607itv2	276	1	The	the	DT
cord-313312-h607itv2	276	2	stoichiometry	stoichiometry	NN
cord-313312-h607itv2	276	3	of	of	IN
cord-313312-h607itv2	276	4	antibody	antibody	NN
cord-313312-h607itv2	276	5	-	-	HYPH
cord-313312-h607itv2	276	6	mediated	mediate	VBN
cord-313312-h607itv2	276	7	neutralization	neutralization	NN
cord-313312-h607itv2	276	8	and	and	CC
cord-313312-h607itv2	276	9	enhancement	enhancement	NN
cord-313312-h607itv2	276	10	of	of	IN
cord-313312-h607itv2	276	11	West	West	NNP
cord-313312-h607itv2	276	12	Nile	Nile	NNP
cord-313312-h607itv2	276	13	virus	virus	NN
cord-313312-h607itv2	276	14	infection	infection	NN
cord-313312-h607itv2	276	15	Structural	Structural	NNP
cord-313312-h607itv2	276	16	Insights	Insights	NNPS
cord-313312-h607itv2	276	17	into	into	IN
cord-313312-h607itv2	276	18	the	the	DT
cord-313312-h607itv2	276	19	Mechanisms	Mechanisms	NNPS
cord-313312-h607itv2	276	20	of	of	IN
cord-313312-h607itv2	276	21	Antibody	Antibody	NNP
cord-313312-h607itv2	276	22	-	-	HYPH
cord-313312-h607itv2	276	23	Mediated	mediate	VBN
cord-313312-h607itv2	276	24	Neutralization	neutralization	NN
cord-313312-h607itv2	276	25	of	of	IN
cord-313312-h607itv2	276	26	Flavivirus	Flavivirus	NNP
cord-313312-h607itv2	276	27	Infection	infection	NN
cord-313312-h607itv2	276	28	:	:	:
cord-313312-h607itv2	276	29	Implications	implication	NNS
cord-313312-h607itv2	276	30	for	for	IN
cord-313312-h607itv2	276	31	Vaccine	Vaccine	NNP
cord-313312-h607itv2	276	32	Development	Development	NNP
cord-313312-h607itv2	276	33	Antibody	Antibody	NNP
cord-313312-h607itv2	276	34	-	-	HYPH
cord-313312-h607itv2	276	35	mediated	mediate	VBN
cord-313312-h607itv2	276	36	neutralization	neutralization	NN
cord-313312-h607itv2	276	37	of	of	IN
cord-313312-h607itv2	276	38	flaviviruses	flavivirus	NNS
cord-313312-h607itv2	276	39	:	:	:
cord-313312-h607itv2	276	40	A	a	DT
cord-313312-h607itv2	276	41	reductionist	reductionist	JJ
cord-313312-h607itv2	276	42	view	view	NN
cord-313312-h607itv2	276	43	Structure	structure	NN
cord-313312-h607itv2	276	44	of	of	IN
cord-313312-h607itv2	276	45	the	the	DT
cord-313312-h607itv2	276	46	Fab	Fab	NNP
cord-313312-h607itv2	276	47	-	-	HYPH
cord-313312-h607itv2	276	48	labeled	label	VBN
cord-313312-h607itv2	276	49	"	"	``
cord-313312-h607itv2	276	50	breathing	breathe	VBG
cord-313312-h607itv2	276	51	"	"	''
cord-313312-h607itv2	276	52	state	state	NN
cord-313312-h607itv2	276	53	of	of	IN
cord-313312-h607itv2	276	54	native	native	JJ
cord-313312-h607itv2	276	55	poliovirus	poliovirus	NN
cord-313312-h607itv2	276	56	Fc	Fc	NNP
cord-313312-h607itv2	276	57	receptors	receptor	NNS
cord-313312-h607itv2	276	58	and	and	CC
cord-313312-h607itv2	276	59	their	-PRON-	PRP$
cord-313312-h607itv2	276	60	influence	influence	NN
cord-313312-h607itv2	276	61	on	on	IN
cord-313312-h607itv2	276	62	efficacy	efficacy	NN
cord-313312-h607itv2	276	63	of	of	IN
cord-313312-h607itv2	276	64	therapeutic	therapeutic	JJ
cord-313312-h607itv2	276	65	antibodies	antibody	NNS
cord-313312-h607itv2	276	66	for	for	IN
cord-313312-h607itv2	276	67	treatment	treatment	NN
cord-313312-h607itv2	276	68	of	of	IN
cord-313312-h607itv2	276	69	viral	viral	JJ
cord-313312-h607itv2	276	70	diseases	disease	NNS
cord-313312-h607itv2	276	71	Ligation	Ligation	NNP
cord-313312-h607itv2	276	72	of	of	IN
cord-313312-h607itv2	276	73	Fc	Fc	NNP
cord-313312-h607itv2	276	74	gamma	gamma	NN
cord-313312-h607itv2	276	75	receptor	receptor	NN
cord-313312-h607itv2	277	1	IIB	IIB	NNP
cord-313312-h607itv2	277	2	inhibits	inhibit	VBZ
cord-313312-h607itv2	277	3	antibody	antibody	NN
cord-313312-h607itv2	277	4	-	-	HYPH
cord-313312-h607itv2	277	5	dependent	dependent	JJ
cord-313312-h607itv2	277	6	enhancement	enhancement	NN
cord-313312-h607itv2	277	7	of	of	IN
cord-313312-h607itv2	277	8	dengue	dengue	NN
cord-313312-h607itv2	277	9	virus	virus	NN
cord-313312-h607itv2	277	10	infection	infection	NN
cord-313312-h607itv2	277	11	Pathogenic	Pathogenic	NNP
cord-313312-h607itv2	277	12	Exploitation	Exploitation	NNP
cord-313312-h607itv2	277	13	of	of	IN
cord-313312-h607itv2	277	14	Fc	Fc	NNP
cord-313312-h607itv2	277	15	Activity	Activity	NNP
cord-313312-h607itv2	277	16	FcgammaRIIB	FcgammaRIIB	NNP
cord-313312-h607itv2	277	17	in	in	IN
cord-313312-h607itv2	277	18	IgG	IgG	NNP
cord-313312-h607itv2	277	19	-	-	HYPH
cord-313312-h607itv2	277	20	mediated	mediate	VBN
cord-313312-h607itv2	277	21	suppression	suppression	NN
cord-313312-h607itv2	277	22	of	of	IN
cord-313312-h607itv2	277	23	antibody	antibody	NN
cord-313312-h607itv2	277	24	responses	response	NNS
cord-313312-h607itv2	277	25	:	:	:
cord-313312-h607itv2	278	1	Different	different	JJ
cord-313312-h607itv2	278	2	impact	impact	NN
cord-313312-h607itv2	278	3	in	in	IN
cord-313312-h607itv2	278	4	vivo	vivo	NN
cord-313312-h607itv2	278	5	and	and	CC
cord-313312-h607itv2	279	1	in	in	FW
cord-313312-h607itv2	279	2	vitro	vitro	FW
cord-313312-h607itv2	279	3	Insights	Insights	NNP
cord-313312-h607itv2	279	4	into	into	IN
cord-313312-h607itv2	279	5	the	the	DT
cord-313312-h607itv2	279	6	regulatory	regulatory	JJ
cord-313312-h607itv2	279	7	mechanism	mechanism	NN
cord-313312-h607itv2	279	8	controlling	control	VBG
cord-313312-h607itv2	279	9	the	the	DT
cord-313312-h607itv2	279	10	inhibition	inhibition	NN
cord-313312-h607itv2	279	11	of	of	IN
cord-313312-h607itv2	279	12	vaccine	vaccine	NN
cord-313312-h607itv2	279	13	-	-	HYPH
cord-313312-h607itv2	279	14	induced	induce	VBN
cord-313312-h607itv2	279	15	seroconversion	seroconversion	NN
cord-313312-h607itv2	279	16	by	by	IN
cord-313312-h607itv2	279	17	maternal	maternal	JJ
cord-313312-h607itv2	279	18	antibodies	antibody	NNS
cord-313312-h607itv2	279	19	Protective	protective	JJ
cord-313312-h607itv2	279	20	efficacy	efficacy	NN
cord-313312-h607itv2	279	21	against	against	IN
cord-313312-h607itv2	279	22	respiratory	respiratory	JJ
cord-313312-h607itv2	279	23	syncytial	syncytial	JJ
cord-313312-h607itv2	279	24	virus	virus	NN
cord-313312-h607itv2	279	25	following	follow	VBG
cord-313312-h607itv2	279	26	murine	murine	JJ
cord-313312-h607itv2	279	27	neonatal	neonatal	JJ
cord-313312-h607itv2	279	28	immunization	immunization	NN
cord-313312-h607itv2	279	29	with	with	IN
cord-313312-h607itv2	279	30	BBG2Na	BBG2Na	NNP
cord-313312-h607itv2	279	31	vaccine	vaccine	NN
cord-313312-h607itv2	279	32	:	:	:
cord-313312-h607itv2	279	33	Influence	influence	NN
cord-313312-h607itv2	279	34	of	of	IN
cord-313312-h607itv2	279	35	adjuvants	adjuvant	NNS
cord-313312-h607itv2	279	36	and	and	CC
cord-313312-h607itv2	279	37	maternal	maternal	JJ
cord-313312-h607itv2	279	38	antibodies	antibody	NNS
cord-313312-h607itv2	279	39	Studies	Studies	NNPS
cord-313312-h607itv2	279	40	on	on	IN
cord-313312-h607itv2	279	41	the	the	DT
cord-313312-h607itv2	279	42	Mechanism	Mechanism	NNP
cord-313312-h607itv2	279	43	by	by	IN
cord-313312-h607itv2	279	44	Which	which	WDT
cord-313312-h607itv2	279	45	Antigen	Antigen	NNP
cord-313312-h607itv2	279	46	-	-	HYPH
cord-313312-h607itv2	279	47	Specific	specific	JJ
cord-313312-h607itv2	279	48	IgG	igg	NN
cord-313312-h607itv2	279	49	Suppresses	suppress	VBZ
cord-313312-h607itv2	279	50	Primary	Primary	NNP
cord-313312-h607itv2	279	51	Antibody	Antibody	NNP
cord-313312-h607itv2	279	52	Responses	Responses	NNPS
cord-313312-h607itv2	280	1	:	:	:
cord-313312-h607itv2	280	2	Evidence	evidence	NN
cord-313312-h607itv2	280	3	for	for	IN
cord-313312-h607itv2	280	4	Epitope	Epitope	NNP
cord-313312-h607itv2	280	5	Masking	masking	NN
cord-313312-h607itv2	280	6	and	and	CC
cord-313312-h607itv2	280	7	Decreased	Decreased	NNP
cord-313312-h607itv2	280	8	Localization	Localization	NNP
cord-313312-h607itv2	280	9	of	of	IN
cord-313312-h607itv2	280	10	Antigen	Antigen	NNP
cord-313312-h607itv2	280	11	in	in	IN
cord-313312-h607itv2	280	12	the	the	DT
cord-313312-h607itv2	280	13	Spleen	Spleen	NNP
cord-313312-h607itv2	280	14	Immunoregulation	Immunoregulation	NNP
cord-313312-h607itv2	280	15	by	by	IN
cord-313312-h607itv2	280	16	monoclonal	monoclonal	JJ
cord-313312-h607itv2	280	17	sheep	sheep	NN
cord-313312-h607itv2	280	18	erythrocyte	erythrocyte	NN
cord-313312-h607itv2	280	19	-	-	HYPH
cord-313312-h607itv2	280	20	specific	specific	JJ
cord-313312-h607itv2	280	21	IgG	igg	NN
cord-313312-h607itv2	280	22	antibodies	antibody	NNS
cord-313312-h607itv2	280	23	:	:	:
cord-313312-h607itv2	280	24	Suppression	suppression	NN
cord-313312-h607itv2	280	25	is	be	VBZ
cord-313312-h607itv2	280	26	correlated	correlate	VBN
cord-313312-h607itv2	280	27	to	to	IN
cord-313312-h607itv2	280	28	level	level	NN
cord-313312-h607itv2	280	29	of	of	IN
cord-313312-h607itv2	280	30	antigen	antigen	NN
cord-313312-h607itv2	280	31	binding	binding	NN
cord-313312-h607itv2	280	32	and	and	CC
cord-313312-h607itv2	280	33	not	not	RB
cord-313312-h607itv2	280	34	to	to	IN
cord-313312-h607itv2	280	35	isotype	isotype	JJ
cord-313312-h607itv2	280	36	Intrinsic	intrinsic	JJ
cord-313312-h607itv2	280	37	antibody	antibody	NN
cord-313312-h607itv2	280	38	-	-	HYPH
cord-313312-h607itv2	280	39	dependent	dependent	JJ
cord-313312-h607itv2	280	40	enhancement	enhancement	NN
cord-313312-h607itv2	280	41	of	of	IN
cord-313312-h607itv2	280	42	microbial	microbial	JJ
cord-313312-h607itv2	280	43	infection	infection	NN
cord-313312-h607itv2	280	44	in	in	IN
cord-313312-h607itv2	280	45	macrophages	macrophage	NNS
cord-313312-h607itv2	280	46	:	:	:
cord-313312-h607itv2	280	47	Disease	disease	NN
cord-313312-h607itv2	280	48	regulation	regulation	NN
cord-313312-h607itv2	280	49	by	by	IN
cord-313312-h607itv2	280	50	immune	immune	JJ
cord-313312-h607itv2	280	51	complexes	complex	NNS
cord-313312-h607itv2	280	52	Dengue	dengue	NN
cord-313312-h607itv2	280	53	Virus	virus	NN
cord-313312-h607itv2	280	54	Neutralization	neutralization	NN
cord-313312-h607itv2	280	55	in	in	IN
cord-313312-h607itv2	280	56	Cells	cell	NNS
cord-313312-h607itv2	280	57	Expressing	express	VBG
cord-313312-h607itv2	280	58	Fc	Fc	NNP
cord-313312-h607itv2	280	59	Gamma	Gamma	NNP
cord-313312-h607itv2	280	60	Receptors	Receptors	NNP
cord-313312-h607itv2	280	61	Differential	Differential	NNP
cord-313312-h607itv2	280	62	Enhancement	Enhancement	NNP
cord-313312-h607itv2	280	63	of	of	IN
cord-313312-h607itv2	280	64	Dengue	Dengue	NNP
cord-313312-h607itv2	280	65	Virus	Virus	NNP
cord-313312-h607itv2	280	66	Immune	immune	VBP
cord-313312-h607itv2	280	67	Complex	complex	JJ
cord-313312-h607itv2	280	68	Infectivity	infectivity	NN
cord-313312-h607itv2	280	69	Mediated	mediate	VBN
cord-313312-h607itv2	280	70	by	by	IN
cord-313312-h607itv2	280	71	Signaling	signal	VBG
cord-313312-h607itv2	280	72	-	-	HYPH
cord-313312-h607itv2	280	73	Competent	competent	JJ
cord-313312-h607itv2	280	74	and	and	CC
cord-313312-h607itv2	280	75	Signaling	Signaling	NNP
cord-313312-h607itv2	280	76	-	-	HYPH
cord-313312-h607itv2	280	77	Incompetent	Incompetent	NNP
cord-313312-h607itv2	280	78	Human	human	JJ
cord-313312-h607itv2	280	79	FcγRIA	FcγRIA	NNS
cord-313312-h607itv2	280	80	(	(	-LRB-
cord-313312-h607itv2	280	81	CD64	CD64	NNP
cord-313312-h607itv2	280	82	)	)	-RRB-
cord-313312-h607itv2	280	83	or	or	CC
cord-313312-h607itv2	280	84	FcγRIIA	FcγRIIA	NNP
cord-313312-h607itv2	280	85	(	(	-LRB-
cord-313312-h607itv2	280	86	CD32	CD32	NNP
cord-313312-h607itv2	280	87	)	)	-RRB-
cord-313312-h607itv2	280	88	Differential	differential	JJ
cord-313312-h607itv2	280	89	signal	signal	NN
cord-313312-h607itv2	280	90	transduction	transduction	NN
cord-313312-h607itv2	280	91	,	,	,
cord-313312-h607itv2	280	92	membrane	membrane	NN
cord-313312-h607itv2	280	93	trafficking	trafficking	NN
cord-313312-h607itv2	280	94	,	,	,
cord-313312-h607itv2	280	95	and	and	CC
cord-313312-h607itv2	280	96	immune	immune	JJ
cord-313312-h607itv2	280	97	effector	effector	NN
cord-313312-h607itv2	280	98	functions	function	NNS
cord-313312-h607itv2	280	99	mediated	mediate	VBN
cord-313312-h607itv2	280	100	by	by	IN
cord-313312-h607itv2	280	101	FcγRI	FcγRI	NNP
cord-313312-h607itv2	280	102	versus	versus	IN
cord-313312-h607itv2	280	103	FcγRIIa	FcγRIIa	NNP
cord-313312-h607itv2	280	104	Antibody	Antibody	NNP
cord-313312-h607itv2	280	105	-	-	HYPH
cord-313312-h607itv2	280	106	Dependent	Dependent	NNP
cord-313312-h607itv2	280	107	Enhancement	Enhancement	NNP
cord-313312-h607itv2	280	108	of	of	IN
cord-313312-h607itv2	280	109	Dengue	Dengue	NNP
cord-313312-h607itv2	280	110	Virus	Virus	NNP
cord-313312-h607itv2	280	111	Infection	Infection	NNP
cord-313312-h607itv2	280	112	in	in	IN
cord-313312-h607itv2	280	113	Primary	Primary	NNP
cord-313312-h607itv2	280	114	Human	Human	NNP
cord-313312-h607itv2	280	115	Macrophages	Macrophages	NNPS
cord-313312-h607itv2	280	116	;	;	:
cord-313312-h607itv2	280	117	Balancing	balance	VBG
cord-313312-h607itv2	280	118	Higher	high	JJR
cord-313312-h607itv2	280	119	Fusion	Fusion	NNP
cord-313312-h607itv2	280	120	against	against	IN
cord-313312-h607itv2	280	121	Antiviral	Antiviral	NNP
cord-313312-h607itv2	280	122	Responses	Responses	NNPS
cord-313312-h607itv2	280	123	Class	Class	NNP
cord-313312-h607itv2	280	124	IV	IV	NNP
cord-313312-h607itv2	280	125	semaphorin	semaphorin	NNP
cord-313312-h607itv2	280	126	Sema4A	Sema4A	NNP
cord-313312-h607itv2	280	127	enhances	enhance	VBZ
cord-313312-h607itv2	280	128	T	t	NN
cord-313312-h607itv2	280	129	-	-	HYPH
cord-313312-h607itv2	280	130	cell	cell	NN
cord-313312-h607itv2	280	131	activation	activation	NN
cord-313312-h607itv2	280	132	and	and	CC
cord-313312-h607itv2	280	133	interacts	interact	VBZ
cord-313312-h607itv2	280	134	with	with	IN
cord-313312-h607itv2	280	135	Tim-2	Tim-2	NNP
cord-313312-h607itv2	280	136	Nonredundant	Nonredundant	NNP
cord-313312-h607itv2	280	137	Roles	role	NNS
cord-313312-h607itv2	280	138	of	of	IN
cord-313312-h607itv2	280	139	Sema4A	Sema4A	NNP
cord-313312-h607itv2	280	140	in	in	IN
cord-313312-h607itv2	280	141	the	the	DT
cord-313312-h607itv2	280	142	Immune	Immune	NNP
cord-313312-h607itv2	280	143	System	System	NNP
cord-313312-h607itv2	280	144	:	:	:
cord-313312-h607itv2	280	145	Defective	defective	JJ
cord-313312-h607itv2	280	146	T	t	NN
cord-313312-h607itv2	280	147	Cell	cell	NN
cord-313312-h607itv2	280	148	Priming	Priming	NNP
cord-313312-h607itv2	280	149	and	and	CC
cord-313312-h607itv2	280	150	Th1	th1	NN
cord-313312-h607itv2	280	151	/	/	SYM
cord-313312-h607itv2	280	152	Th2	th2	CD
cord-313312-h607itv2	280	153	Regulation	regulation	NN
cord-313312-h607itv2	280	154	in	in	IN
cord-313312-h607itv2	280	155	Sema4A	Sema4A	NNP
cord-313312-h607itv2	280	156	-	-	HYPH
cord-313312-h607itv2	280	157	Deficient	deficient	JJ
cord-313312-h607itv2	280	158	Mice	mouse	NNS
cord-313312-h607itv2	280	159	Metabolic	metabolic	JJ
cord-313312-h607itv2	280	160	perturbations	perturbation	NNS
cord-313312-h607itv2	280	161	and	and	CC
cord-313312-h607itv2	280	162	cellular	cellular	JJ
cord-313312-h607itv2	280	163	stress	stress	NN
cord-313312-h607itv2	280	164	underpin	underpin	VBP
cord-313312-h607itv2	280	165	susceptibility	susceptibility	NN
cord-313312-h607itv2	280	166	to	to	IN
cord-313312-h607itv2	280	167	symptomatic	symptomatic	JJ
cord-313312-h607itv2	280	168	live	live	RB
cord-313312-h607itv2	280	169	-	-	HYPH
cord-313312-h607itv2	280	170	attenuated	attenuate	VBN
cord-313312-h607itv2	280	171	yellow	yellow	JJ
cord-313312-h607itv2	280	172	fever	fever	NN
cord-313312-h607itv2	280	173	infection	infection	NN
cord-313312-h607itv2	281	1	Broad	broad	JJ
cord-313312-h607itv2	281	2	immune	immune	JJ
cord-313312-h607itv2	281	3	activation	activation	NN
cord-313312-h607itv2	281	4	underlies	underlie	VBZ
cord-313312-h607itv2	281	5	shared	share	VBN
cord-313312-h607itv2	281	6	set	set	NN
cord-313312-h607itv2	281	7	point	point	NN
cord-313312-h607itv2	281	8	signatures	signature	NNS
cord-313312-h607itv2	281	9	for	for	IN
cord-313312-h607itv2	281	10	vaccine	vaccine	NN
cord-313312-h607itv2	281	11	responsiveness	responsiveness	NN
cord-313312-h607itv2	281	12	in	in	IN
cord-313312-h607itv2	281	13	healthy	healthy	JJ
cord-313312-h607itv2	281	14	individuals	individual	NNS
cord-313312-h607itv2	281	15	and	and	CC
cord-313312-h607itv2	281	16	disease	disease	NN
cord-313312-h607itv2	281	17	activity	activity	NN
cord-313312-h607itv2	281	18	in	in	IN
cord-313312-h607itv2	281	19	patients	patient	NNS
cord-313312-h607itv2	281	20	with	with	IN
cord-313312-h607itv2	281	21	lupus	lupus	NN
cord-313312-h607itv2	282	1	This	this	DT
cord-313312-h607itv2	282	2	article	article	NN
cord-313312-h607itv2	282	3	is	be	VBZ
cord-313312-h607itv2	282	4	an	an	DT
cord-313312-h607itv2	282	5	open	open	JJ
cord-313312-h607itv2	282	6	access	access	NN
cord-313312-h607itv2	282	7	article	article	NN
cord-313312-h607itv2	282	8	distributed	distribute	VBN
cord-313312-h607itv2	282	9	under	under	IN
cord-313312-h607itv2	282	10	the	the	DT
cord-313312-h607itv2	282	11	terms	term	NNS
cord-313312-h607itv2	282	12	and	and	CC
cord-313312-h607itv2	282	13	conditions	condition	NNS
cord-313312-h607itv2	282	14	of	of	IN
cord-313312-h607itv2	282	15	the	the	DT
cord-313312-h607itv2	282	16	Creative	Creative	NNP
cord-313312-h607itv2	282	17	Commons	Commons	NNP
cord-313312-h607itv2	282	18	Attribution	Attribution	NNP
cord-313312-h607itv2	282	19	(	(	-LRB-
cord-313312-h607itv2	282	20	CC	CC	NNP
cord-313312-h607itv2	282	21	BY	by	IN
cord-313312-h607itv2	282	22	)	)	-RRB-
cord-313312-h607itv2	282	23	license	license	NN
cord-313312-h607itv2	283	1	The	the	DT
cord-313312-h607itv2	283	2	authors	author	NNS
cord-313312-h607itv2	283	3	declare	declare	VBP
cord-313312-h607itv2	283	4	no	no	DT
cord-313312-h607itv2	283	5	conflict	conflict	NN
cord-313312-h607itv2	283	6	of	of	IN
cord-313312-h607itv2	283	7	interest	interest	NN
cord-313312-h607itv2	283	8	.	.	.