id	sid	tid	token	lemma	pos
cord-263699-gosqpg3k	1	1	key	key	NN
cord-263699-gosqpg3k	1	2	:	:	:
cord-263699-gosqpg3k	2	1	cord-263699-gosqpg3k	cord-263699-gosqpg3k	JJR
cord-263699-gosqpg3k	2	2	authors	author	NNS
cord-263699-gosqpg3k	2	3	:	:	:
cord-263699-gosqpg3k	2	4	Martínez	Martínez	NNP
cord-263699-gosqpg3k	2	5	,	,	,
cord-263699-gosqpg3k	2	6	José	José	NNP
cord-263699-gosqpg3k	2	7	L.	L.	NNP
cord-263699-gosqpg3k	2	8	;	;	:
cord-263699-gosqpg3k	2	9	Arias	Arias	NNP
cord-263699-gosqpg3k	2	10	,	,	,
cord-263699-gosqpg3k	2	11	Carlos	Carlos	NNP
cord-263699-gosqpg3k	2	12	F.	F.	NNP
cord-263699-gosqpg3k	2	13	title	title	NN
cord-263699-gosqpg3k	2	14	:	:	:
cord-263699-gosqpg3k	2	15	Role	role	NN
cord-263699-gosqpg3k	2	16	of	of	IN
cord-263699-gosqpg3k	2	17	the	the	DT
cord-263699-gosqpg3k	2	18	Guanine	Guanine	NNP
cord-263699-gosqpg3k	2	19	Nucleotide	Nucleotide	NNP
cord-263699-gosqpg3k	2	20	Exchange	Exchange	NNP
cord-263699-gosqpg3k	2	21	Factor	Factor	NNP
cord-263699-gosqpg3k	2	22	GBF1	GBF1	NNP
cord-263699-gosqpg3k	2	23	in	in	IN
cord-263699-gosqpg3k	2	24	the	the	DT
cord-263699-gosqpg3k	2	25	Replication	Replication	NNP
cord-263699-gosqpg3k	2	26	of	of	IN
cord-263699-gosqpg3k	2	27	RNA	RNA	NNP
cord-263699-gosqpg3k	2	28	Viruses	Viruses	NNPS
cord-263699-gosqpg3k	2	29	date	date	NN
cord-263699-gosqpg3k	2	30	:	:	:
cord-263699-gosqpg3k	2	31	2020	2020	CD
cord-263699-gosqpg3k	2	32	-	-	HYPH
cord-263699-gosqpg3k	2	33	06	06	CD
cord-263699-gosqpg3k	2	34	-	-	HYPH
cord-263699-gosqpg3k	2	35	24	24	CD
cord-263699-gosqpg3k	2	36	journal	journal	NN
cord-263699-gosqpg3k	2	37	:	:	:
cord-263699-gosqpg3k	3	1	Viruses	virus	NNS
cord-263699-gosqpg3k	3	2	DOI	DOI	NNP
cord-263699-gosqpg3k	3	3	:	:	:
cord-263699-gosqpg3k	4	1	10.3390/	10.3390/	CD
cord-263699-gosqpg3k	5	1	v12060682	v12060682	NNP
cord-263699-gosqpg3k	5	2	sha	sha	NNP
cord-263699-gosqpg3k	5	3	:	:	:
cord-263699-gosqpg3k	6	1	3d65121d13d1723f38ff42a20353ff1c9a3ca468	3d65121d13d1723f38ff42a20353ff1c9a3ca468	CD
cord-263699-gosqpg3k	6	2	doc_id	doc_id	CD
cord-263699-gosqpg3k	6	3	:	:	:
cord-263699-gosqpg3k	6	4	263699	263699	CD
cord-263699-gosqpg3k	6	5	cord_uid	cord_uid	NNS
cord-263699-gosqpg3k	6	6	:	:	:
cord-263699-gosqpg3k	7	1	gosqpg3k	gosqpg3k	NNS
cord-263699-gosqpg3k	8	1	The	the	DT
cord-263699-gosqpg3k	8	2	guanine	guanine	NN
cord-263699-gosqpg3k	8	3	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	8	4	exchange	exchange	NN
cord-263699-gosqpg3k	8	5	factor	factor	NN
cord-263699-gosqpg3k	8	6	GBF1	GBF1	NNP
cord-263699-gosqpg3k	8	7	is	be	VBZ
cord-263699-gosqpg3k	8	8	a	a	DT
cord-263699-gosqpg3k	8	9	well	well	RB
cord-263699-gosqpg3k	8	10	-	-	HYPH
cord-263699-gosqpg3k	8	11	known	know	VBN
cord-263699-gosqpg3k	8	12	factor	factor	NN
cord-263699-gosqpg3k	8	13	that	that	WDT
cord-263699-gosqpg3k	8	14	can	can	MD
cord-263699-gosqpg3k	8	15	activate	activate	VB
cord-263699-gosqpg3k	8	16	different	different	JJ
cord-263699-gosqpg3k	8	17	ADP	ADP	NNP
cord-263699-gosqpg3k	8	18	-	-	HYPH
cord-263699-gosqpg3k	8	19	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	8	20	factor	factor	NN
cord-263699-gosqpg3k	8	21	(	(	-LRB-
cord-263699-gosqpg3k	8	22	Arf	Arf	NNP
cord-263699-gosqpg3k	8	23	)	)	-RRB-
cord-263699-gosqpg3k	8	24	proteins	protein	NNS
cord-263699-gosqpg3k	8	25	during	during	IN
cord-263699-gosqpg3k	8	26	the	the	DT
cord-263699-gosqpg3k	8	27	regulation	regulation	NN
cord-263699-gosqpg3k	8	28	of	of	IN
cord-263699-gosqpg3k	8	29	different	different	JJ
cord-263699-gosqpg3k	8	30	cellular	cellular	JJ
cord-263699-gosqpg3k	8	31	vesicular	vesicular	JJ
cord-263699-gosqpg3k	8	32	transport	transport	NN
cord-263699-gosqpg3k	8	33	processes	process	NNS
cord-263699-gosqpg3k	8	34	.	.	.
cord-263699-gosqpg3k	9	1	In	in	IN
cord-263699-gosqpg3k	9	2	the	the	DT
cord-263699-gosqpg3k	9	3	last	last	JJ
cord-263699-gosqpg3k	9	4	decade	decade	NN
cord-263699-gosqpg3k	9	5	,	,	,
cord-263699-gosqpg3k	9	6	it	-PRON-	PRP
cord-263699-gosqpg3k	9	7	has	have	VBZ
cord-263699-gosqpg3k	9	8	become	become	VBN
cord-263699-gosqpg3k	9	9	increasingly	increasingly	RB
cord-263699-gosqpg3k	9	10	evident	evident	JJ
cord-263699-gosqpg3k	9	11	that	that	IN
cord-263699-gosqpg3k	9	12	GBF1	GBF1	NNP
cord-263699-gosqpg3k	9	13	can	can	MD
cord-263699-gosqpg3k	9	14	also	also	RB
cord-263699-gosqpg3k	9	15	regulate	regulate	VB
cord-263699-gosqpg3k	9	16	different	different	JJ
cord-263699-gosqpg3k	9	17	steps	step	NNS
cord-263699-gosqpg3k	9	18	of	of	IN
cord-263699-gosqpg3k	9	19	the	the	DT
cord-263699-gosqpg3k	9	20	replication	replication	NN
cord-263699-gosqpg3k	9	21	cycle	cycle	NN
cord-263699-gosqpg3k	9	22	of	of	IN
cord-263699-gosqpg3k	9	23	RNA	RNA	NNP
cord-263699-gosqpg3k	9	24	viruses	virus	NNS
cord-263699-gosqpg3k	9	25	belonging	belong	VBG
cord-263699-gosqpg3k	9	26	to	to	IN
cord-263699-gosqpg3k	9	27	different	different	JJ
cord-263699-gosqpg3k	9	28	virus	virus	NN
cord-263699-gosqpg3k	9	29	families	family	NNS
cord-263699-gosqpg3k	9	30	.	.	.
cord-263699-gosqpg3k	10	1	GBF1	GBF1	NNP
cord-263699-gosqpg3k	10	2	has	have	VBZ
cord-263699-gosqpg3k	10	3	been	be	VBN
cord-263699-gosqpg3k	10	4	shown	show	VBN
cord-263699-gosqpg3k	10	5	not	not	RB
cord-263699-gosqpg3k	10	6	only	only	RB
cord-263699-gosqpg3k	10	7	to	to	TO
cord-263699-gosqpg3k	10	8	facilitate	facilitate	VB
cord-263699-gosqpg3k	10	9	the	the	DT
cord-263699-gosqpg3k	10	10	intracellular	intracellular	JJ
cord-263699-gosqpg3k	10	11	traffic	traffic	NN
cord-263699-gosqpg3k	10	12	of	of	IN
cord-263699-gosqpg3k	10	13	different	different	JJ
cord-263699-gosqpg3k	10	14	viral	viral	JJ
cord-263699-gosqpg3k	10	15	and	and	CC
cord-263699-gosqpg3k	10	16	cellular	cellular	JJ
cord-263699-gosqpg3k	10	17	elements	element	NNS
cord-263699-gosqpg3k	10	18	during	during	IN
cord-263699-gosqpg3k	10	19	infection	infection	NN
cord-263699-gosqpg3k	10	20	,	,	,
cord-263699-gosqpg3k	10	21	but	but	CC
cord-263699-gosqpg3k	10	22	also	also	RB
cord-263699-gosqpg3k	10	23	to	to	TO
cord-263699-gosqpg3k	10	24	modulate	modulate	VB
cord-263699-gosqpg3k	10	25	the	the	DT
cord-263699-gosqpg3k	10	26	replication	replication	NN
cord-263699-gosqpg3k	10	27	of	of	IN
cord-263699-gosqpg3k	10	28	viral	viral	JJ
cord-263699-gosqpg3k	10	29	RNA	RNA	NNP
cord-263699-gosqpg3k	10	30	,	,	,
cord-263699-gosqpg3k	10	31	the	the	DT
cord-263699-gosqpg3k	10	32	formation	formation	NN
cord-263699-gosqpg3k	10	33	and	and	CC
cord-263699-gosqpg3k	10	34	maturation	maturation	NN
cord-263699-gosqpg3k	10	35	of	of	IN
cord-263699-gosqpg3k	10	36	viral	viral	JJ
cord-263699-gosqpg3k	10	37	replication	replication	NN
cord-263699-gosqpg3k	10	38	complexes	complex	NNS
cord-263699-gosqpg3k	10	39	,	,	,
cord-263699-gosqpg3k	10	40	and	and	CC
cord-263699-gosqpg3k	10	41	the	the	DT
cord-263699-gosqpg3k	10	42	processing	processing	NN
cord-263699-gosqpg3k	10	43	of	of	IN
cord-263699-gosqpg3k	10	44	viral	viral	JJ
cord-263699-gosqpg3k	10	45	proteins	protein	NNS
cord-263699-gosqpg3k	10	46	through	through	IN
cord-263699-gosqpg3k	10	47	mechanisms	mechanism	NNS
cord-263699-gosqpg3k	10	48	that	that	WDT
cord-263699-gosqpg3k	10	49	do	do	VBP
cord-263699-gosqpg3k	10	50	not	not	RB
cord-263699-gosqpg3k	10	51	depend	depend	VB
cord-263699-gosqpg3k	10	52	on	on	IN
cord-263699-gosqpg3k	10	53	its	-PRON-	PRP$
cord-263699-gosqpg3k	10	54	canonical	canonical	JJ
cord-263699-gosqpg3k	10	55	role	role	NN
cord-263699-gosqpg3k	10	56	in	in	IN
cord-263699-gosqpg3k	10	57	intracellular	intracellular	JJ
cord-263699-gosqpg3k	10	58	transport	transport	NN
cord-263699-gosqpg3k	10	59	.	.	.
cord-263699-gosqpg3k	11	1	Here	here	RB
cord-263699-gosqpg3k	11	2	,	,	,
cord-263699-gosqpg3k	11	3	we	-PRON-	PRP
cord-263699-gosqpg3k	11	4	review	review	VBP
cord-263699-gosqpg3k	11	5	the	the	DT
cord-263699-gosqpg3k	11	6	various	various	JJ
cord-263699-gosqpg3k	11	7	roles	role	NNS
cord-263699-gosqpg3k	11	8	that	that	WDT
cord-263699-gosqpg3k	11	9	GBF1	GBF1	NNP
cord-263699-gosqpg3k	11	10	plays	play	VBZ
cord-263699-gosqpg3k	11	11	during	during	IN
cord-263699-gosqpg3k	11	12	the	the	DT
cord-263699-gosqpg3k	11	13	replication	replication	NN
cord-263699-gosqpg3k	11	14	of	of	IN
cord-263699-gosqpg3k	11	15	different	different	JJ
cord-263699-gosqpg3k	11	16	RNA	RNA	NNP
cord-263699-gosqpg3k	11	17	viruses	virus	NNS
cord-263699-gosqpg3k	11	18	.	.	.
cord-263699-gosqpg3k	12	1	Eukaryotic	eukaryotic	JJ
cord-263699-gosqpg3k	12	2	cells	cell	NNS
cord-263699-gosqpg3k	12	3	contain	contain	VBP
cord-263699-gosqpg3k	12	4	a	a	DT
cord-263699-gosqpg3k	12	5	collection	collection	NN
cord-263699-gosqpg3k	12	6	of	of	IN
cord-263699-gosqpg3k	12	7	diverse	diverse	JJ
cord-263699-gosqpg3k	12	8	organelles	organelle	NNS
cord-263699-gosqpg3k	12	9	that	that	WDT
cord-263699-gosqpg3k	12	10	perform	perform	VBP
cord-263699-gosqpg3k	12	11	specialized	specialized	JJ
cord-263699-gosqpg3k	12	12	functions	function	NNS
cord-263699-gosqpg3k	12	13	depending	depend	VBG
cord-263699-gosqpg3k	12	14	on	on	IN
cord-263699-gosqpg3k	12	15	the	the	DT
cord-263699-gosqpg3k	12	16	enzymatic	enzymatic	JJ
cord-263699-gosqpg3k	12	17	activities	activity	NNS
cord-263699-gosqpg3k	12	18	of	of	IN
cord-263699-gosqpg3k	12	19	their	-PRON-	PRP$
cord-263699-gosqpg3k	12	20	components	component	NNS
cord-263699-gosqpg3k	12	21	.	.	.
cord-263699-gosqpg3k	13	1	Although	although	IN
cord-263699-gosqpg3k	13	2	these	these	DT
cord-263699-gosqpg3k	13	3	organelles	organelle	NNS
cord-263699-gosqpg3k	13	4	are	be	VBP
cord-263699-gosqpg3k	13	5	spatially	spatially	RB
cord-263699-gosqpg3k	13	6	separated	separate	VBN
cord-263699-gosqpg3k	13	7	,	,	,
cord-263699-gosqpg3k	13	8	there	there	EX
cord-263699-gosqpg3k	13	9	is	be	VBZ
cord-263699-gosqpg3k	13	10	a	a	DT
cord-263699-gosqpg3k	13	11	dynamic	dynamic	JJ
cord-263699-gosqpg3k	13	12	interaction	interaction	NN
cord-263699-gosqpg3k	13	13	between	between	IN
cord-263699-gosqpg3k	13	14	them	-PRON-	PRP
cord-263699-gosqpg3k	13	15	by	by	IN
cord-263699-gosqpg3k	13	16	different	different	JJ
cord-263699-gosqpg3k	13	17	trafficking	trafficking	NN
cord-263699-gosqpg3k	13	18	events	event	NNS
cord-263699-gosqpg3k	13	19	,	,	,
cord-263699-gosqpg3k	13	20	some	some	DT
cord-263699-gosqpg3k	13	21	of	of	IN
cord-263699-gosqpg3k	13	22	which	which	WDT
cord-263699-gosqpg3k	13	23	are	be	VBP
cord-263699-gosqpg3k	13	24	mediated	mediate	VBN
cord-263699-gosqpg3k	13	25	by	by	IN
cord-263699-gosqpg3k	13	26	vesicle	vesicle	NN
cord-263699-gosqpg3k	13	27	transport	transport	NN
cord-263699-gosqpg3k	13	28	[	[	-LRB-
cord-263699-gosqpg3k	13	29	1	1	CD
cord-263699-gosqpg3k	13	30	]	]	-RRB-
cord-263699-gosqpg3k	13	31	.	.	.
cord-263699-gosqpg3k	14	1	This	this	DT
cord-263699-gosqpg3k	14	2	transport	transport	NN
cord-263699-gosqpg3k	14	3	is	be	VBZ
cord-263699-gosqpg3k	14	4	responsible	responsible	JJ
cord-263699-gosqpg3k	14	5	for	for	IN
cord-263699-gosqpg3k	14	6	the	the	DT
cord-263699-gosqpg3k	14	7	proper	proper	JJ
cord-263699-gosqpg3k	14	8	intracellular	intracellular	JJ
cord-263699-gosqpg3k	14	9	distribution	distribution	NN
cord-263699-gosqpg3k	14	10	of	of	IN
cord-263699-gosqpg3k	14	11	proteins	protein	NNS
cord-263699-gosqpg3k	14	12	and	and	CC
cord-263699-gosqpg3k	14	13	lipids	lipid	NNS
cord-263699-gosqpg3k	14	14	and	and	CC
cord-263699-gosqpg3k	14	15	is	be	VBZ
cord-263699-gosqpg3k	14	16	essential	essential	JJ
cord-263699-gosqpg3k	14	17	to	to	TO
cord-263699-gosqpg3k	14	18	sustain	sustain	VB
cord-263699-gosqpg3k	14	19	the	the	DT
cord-263699-gosqpg3k	14	20	correct	correct	JJ
cord-263699-gosqpg3k	14	21	function	function	NN
cord-263699-gosqpg3k	14	22	and	and	CC
cord-263699-gosqpg3k	14	23	structure	structure	NN
cord-263699-gosqpg3k	14	24	of	of	IN
cord-263699-gosqpg3k	14	25	cell	cell	NN
cord-263699-gosqpg3k	14	26	organelles	organelle	NNS
cord-263699-gosqpg3k	14	27	[	[	-LRB-
cord-263699-gosqpg3k	14	28	2	2	CD
cord-263699-gosqpg3k	14	29	]	]	-RRB-
cord-263699-gosqpg3k	14	30	[	[	-LRB-
cord-263699-gosqpg3k	14	31	3	3	CD
cord-263699-gosqpg3k	14	32	]	]	-RRB-
cord-263699-gosqpg3k	14	33	[	[	-LRB-
cord-263699-gosqpg3k	14	34	4	4	CD
cord-263699-gosqpg3k	14	35	]	]	-RRB-
cord-263699-gosqpg3k	14	36	[	[	-LRB-
cord-263699-gosqpg3k	14	37	5	5	CD
cord-263699-gosqpg3k	14	38	]	]	-RRB-
cord-263699-gosqpg3k	14	39	[	[	-LRB-
cord-263699-gosqpg3k	14	40	6	6	CD
cord-263699-gosqpg3k	14	41	]	]	-RRB-
cord-263699-gosqpg3k	14	42	[	[	-LRB-
cord-263699-gosqpg3k	14	43	7	7	CD
cord-263699-gosqpg3k	14	44	]	]	-RRB-
cord-263699-gosqpg3k	14	45	.	.	.
cord-263699-gosqpg3k	15	1	In	in	IN
cord-263699-gosqpg3k	15	2	vesicle	vesicle	NN
cord-263699-gosqpg3k	15	3	transport	transport	NN
cord-263699-gosqpg3k	15	4	,	,	,
cord-263699-gosqpg3k	15	5	the	the	DT
cord-263699-gosqpg3k	15	6	proteins	protein	NNS
cord-263699-gosqpg3k	15	7	and	and	CC
cord-263699-gosqpg3k	15	8	lipids	lipid	NNS
cord-263699-gosqpg3k	15	9	to	to	TO
cord-263699-gosqpg3k	15	10	be	be	VB
cord-263699-gosqpg3k	15	11	transported	transport	VBN
cord-263699-gosqpg3k	15	12	are	be	VBP
cord-263699-gosqpg3k	15	13	selectively	selectively	RB
cord-263699-gosqpg3k	15	14	concentrated	concentrate	VBN
cord-263699-gosqpg3k	15	15	on	on	IN
cord-263699-gosqpg3k	15	16	specialized	specialized	JJ
cord-263699-gosqpg3k	15	17	membrane	membrane	NN
cord-263699-gosqpg3k	15	18	sites	site	NNS
cord-263699-gosqpg3k	15	19	of	of	IN
cord-263699-gosqpg3k	15	20	a	a	DT
cord-263699-gosqpg3k	15	21	donor	donor	NN
cord-263699-gosqpg3k	15	22	compartment	compartment	NN
cord-263699-gosqpg3k	15	23	and	and	CC
cord-263699-gosqpg3k	15	24	included	include	VBD
cord-263699-gosqpg3k	15	25	into	into	IN
cord-263699-gosqpg3k	15	26	spherical	spherical	JJ
cord-263699-gosqpg3k	15	27	carrier	carrier	NN
cord-263699-gosqpg3k	15	28	vesicles	vesicle	NNS
cord-263699-gosqpg3k	15	29	coated	coat	VBN
cord-263699-gosqpg3k	15	30	with	with	IN
cord-263699-gosqpg3k	15	31	specific	specific	JJ
cord-263699-gosqpg3k	15	32	proteins	protein	NNS
cord-263699-gosqpg3k	15	33	.	.	.
cord-263699-gosqpg3k	16	1	The	the	DT
cord-263699-gosqpg3k	16	2	vesicles	vesicle	NNS
cord-263699-gosqpg3k	16	3	detach	detach	VBP
cord-263699-gosqpg3k	16	4	from	from	IN
cord-263699-gosqpg3k	16	5	the	the	DT
cord-263699-gosqpg3k	16	6	donor	donor	NN
cord-263699-gosqpg3k	16	7	membrane	membrane	NN
cord-263699-gosqpg3k	16	8	and	and	CC
cord-263699-gosqpg3k	16	9	travel	travel	VB
cord-263699-gosqpg3k	16	10	through	through	IN
cord-263699-gosqpg3k	16	11	the	the	DT
cord-263699-gosqpg3k	16	12	cytoplasm	cytoplasm	NN
cord-263699-gosqpg3k	16	13	until	until	IN
cord-263699-gosqpg3k	16	14	they	-PRON-	PRP
cord-263699-gosqpg3k	16	15	finally	finally	RB
cord-263699-gosqpg3k	16	16	fuse	fuse	VBP
cord-263699-gosqpg3k	16	17	with	with	IN
cord-263699-gosqpg3k	16	18	their	-PRON-	PRP$
cord-263699-gosqpg3k	16	19	target	target	NN
cord-263699-gosqpg3k	16	20	compartment	compartment	NN
cord-263699-gosqpg3k	16	21	to	to	TO
cord-263699-gosqpg3k	16	22	release	release	VB
cord-263699-gosqpg3k	16	23	their	-PRON-	PRP$
cord-263699-gosqpg3k	16	24	content	content	NN
cord-263699-gosqpg3k	16	25	[	[	-LRB-
cord-263699-gosqpg3k	16	26	8	8	CD
cord-263699-gosqpg3k	16	27	]	]	-RRB-
cord-263699-gosqpg3k	16	28	[	[	-LRB-
cord-263699-gosqpg3k	16	29	9	9	CD
cord-263699-gosqpg3k	16	30	]	]	-RRB-
cord-263699-gosqpg3k	16	31	[	[	-LRB-
cord-263699-gosqpg3k	16	32	10	10	CD
cord-263699-gosqpg3k	16	33	]	]	-RRB-
cord-263699-gosqpg3k	16	34	.	.	.
cord-263699-gosqpg3k	17	1	Based	base	VBN
cord-263699-gosqpg3k	17	2	on	on	IN
cord-263699-gosqpg3k	17	3	the	the	DT
cord-263699-gosqpg3k	17	4	protein	protein	NN
cord-263699-gosqpg3k	17	5	elements	element	NNS
cord-263699-gosqpg3k	17	6	that	that	WDT
cord-263699-gosqpg3k	17	7	form	form	VBP
cord-263699-gosqpg3k	17	8	the	the	DT
cord-263699-gosqpg3k	17	9	coat	coat	NN
cord-263699-gosqpg3k	17	10	,	,	,
cord-263699-gosqpg3k	17	11	three	three	CD
cord-263699-gosqpg3k	17	12	important	important	JJ
cord-263699-gosqpg3k	17	13	transport	transport	NN
cord-263699-gosqpg3k	17	14	vesicles	vesicle	NNS
cord-263699-gosqpg3k	17	15	have	have	VBP
cord-263699-gosqpg3k	17	16	been	be	VBN
cord-263699-gosqpg3k	17	17	extensively	extensively	RB
cord-263699-gosqpg3k	17	18	described	describe	VBN
cord-263699-gosqpg3k	17	19	in	in	IN
cord-263699-gosqpg3k	17	20	which	which	WDT
cord-263699-gosqpg3k	17	21	the	the	DT
cord-263699-gosqpg3k	17	22	function	function	NN
cord-263699-gosqpg3k	17	23	depends	depend	VBZ
cord-263699-gosqpg3k	17	24	on	on	IN
cord-263699-gosqpg3k	17	25	either	either	CC
cord-263699-gosqpg3k	17	26	the	the	DT
cord-263699-gosqpg3k	17	27	coatomer	coatomer	NN
cord-263699-gosqpg3k	17	28	protein	protein	NN
cord-263699-gosqpg3k	17	29	I	I	NNP
cord-263699-gosqpg3k	17	30	(	(	-LRB-
cord-263699-gosqpg3k	17	31	COPI	COPI	NNP
cord-263699-gosqpg3k	17	32	)	)	-RRB-
cord-263699-gosqpg3k	17	33	,	,	,
cord-263699-gosqpg3k	17	34	COPII	COPII	NNP
cord-263699-gosqpg3k	17	35	,	,	,
cord-263699-gosqpg3k	17	36	or	or	CC
cord-263699-gosqpg3k	17	37	clathrin	clathrin	NNP
cord-263699-gosqpg3k	17	38	[	[	-LRB-
cord-263699-gosqpg3k	17	39	11	11	CD
cord-263699-gosqpg3k	17	40	,	,	,
cord-263699-gosqpg3k	17	41	12	12	CD
cord-263699-gosqpg3k	17	42	]	]	-RRB-
cord-263699-gosqpg3k	17	43	.	.	.
cord-263699-gosqpg3k	18	1	These	these	DT
cord-263699-gosqpg3k	18	2	vesicles	vesicle	NNS
cord-263699-gosqpg3k	18	3	mediate	mediate	VBP
cord-263699-gosqpg3k	18	4	different	different	JJ
cord-263699-gosqpg3k	18	5	steps	step	NNS
cord-263699-gosqpg3k	18	6	of	of	IN
cord-263699-gosqpg3k	18	7	the	the	DT
cord-263699-gosqpg3k	18	8	secretory	secretory	JJ
cord-263699-gosqpg3k	18	9	pathway	pathway	NN
cord-263699-gosqpg3k	18	10	of	of	IN
cord-263699-gosqpg3k	18	11	the	the	DT
cord-263699-gosqpg3k	18	12	cell	cell	NN
cord-263699-gosqpg3k	18	13	.	.	.
cord-263699-gosqpg3k	19	1	COPII	COPII	NNP
cord-263699-gosqpg3k	19	2	regulates	regulate	VBZ
cord-263699-gosqpg3k	19	3	the	the	DT
cord-263699-gosqpg3k	19	4	anterograde	anterograde	JJ
cord-263699-gosqpg3k	19	5	transport	transport	NN
cord-263699-gosqpg3k	19	6	from	from	IN
cord-263699-gosqpg3k	19	7	the	the	DT
cord-263699-gosqpg3k	19	8	endoplasmic	endoplasmic	NN
cord-263699-gosqpg3k	19	9	reticulum	reticulum	NN
cord-263699-gosqpg3k	19	10	(	(	-LRB-
cord-263699-gosqpg3k	19	11	ER	ER	NNP
cord-263699-gosqpg3k	19	12	)	)	-RRB-
cord-263699-gosqpg3k	19	13	to	to	IN
cord-263699-gosqpg3k	19	14	the	the	DT
cord-263699-gosqpg3k	19	15	Golgi	Golgi	NNP
cord-263699-gosqpg3k	19	16	apparatus	apparatus	NN
cord-263699-gosqpg3k	19	17	[	[	-LRB-
cord-263699-gosqpg3k	19	18	13	13	CD
cord-263699-gosqpg3k	19	19	,	,	,
cord-263699-gosqpg3k	19	20	14	14	CD
cord-263699-gosqpg3k	19	21	]	]	-RRB-
cord-263699-gosqpg3k	19	22	,	,	,
cord-263699-gosqpg3k	19	23	whereas	whereas	IN
cord-263699-gosqpg3k	19	24	COPI	COPI	NNP
cord-263699-gosqpg3k	19	25	facilitates	facilitate	VBZ
cord-263699-gosqpg3k	19	26	the	the	DT
cord-263699-gosqpg3k	19	27	transport	transport	NN
cord-263699-gosqpg3k	19	28	between	between	IN
cord-263699-gosqpg3k	19	29	the	the	DT
cord-263699-gosqpg3k	19	30	Golgi	Golgi	NNP
cord-263699-gosqpg3k	19	31	cisternae	cisternae	NNP
cord-263699-gosqpg3k	19	32	as	as	RB
cord-263699-gosqpg3k	19	33	well	well	RB
cord-263699-gosqpg3k	19	34	as	as	IN
cord-263699-gosqpg3k	19	35	the	the	DT
cord-263699-gosqpg3k	19	36	retrograde	retrograde	JJ
cord-263699-gosqpg3k	19	37	transport	transport	NN
cord-263699-gosqpg3k	19	38	from	from	IN
cord-263699-gosqpg3k	19	39	Golgi	Golgi	NNP
cord-263699-gosqpg3k	19	40	to	to	IN
cord-263699-gosqpg3k	19	41	the	the	DT
cord-263699-gosqpg3k	19	42	ER	ER	NNP
cord-263699-gosqpg3k	19	43	[	[	-LRB-
cord-263699-gosqpg3k	19	44	15	15	CD
cord-263699-gosqpg3k	19	45	]	]	-RRB-
cord-263699-gosqpg3k	19	46	[	[	-LRB-
cord-263699-gosqpg3k	19	47	16	16	CD
cord-263699-gosqpg3k	19	48	]	]	-RRB-
cord-263699-gosqpg3k	19	49	[	[	-LRB-
cord-263699-gosqpg3k	19	50	17	17	CD
cord-263699-gosqpg3k	19	51	]	]	-RRB-
cord-263699-gosqpg3k	19	52	.	.	.
cord-263699-gosqpg3k	20	1	On	on	IN
cord-263699-gosqpg3k	20	2	the	the	DT
cord-263699-gosqpg3k	20	3	other	other	JJ
cord-263699-gosqpg3k	20	4	hand	hand	NN
cord-263699-gosqpg3k	20	5	,	,	,
cord-263699-gosqpg3k	20	6	clathrin	clathrin	NN
cord-263699-gosqpg3k	20	7	-	-	HYPH
cord-263699-gosqpg3k	20	8	coated	coat	VBN
cord-263699-gosqpg3k	20	9	vesicles	vesicle	NNS
cord-263699-gosqpg3k	20	10	direct	direct	VBP
cord-263699-gosqpg3k	20	11	the	the	DT
cord-263699-gosqpg3k	20	12	transport	transport	NN
cord-263699-gosqpg3k	20	13	from	from	IN
cord-263699-gosqpg3k	20	14	the	the	DT
cord-263699-gosqpg3k	20	15	Golgi	Golgi	NNP
cord-263699-gosqpg3k	20	16	to	to	IN
cord-263699-gosqpg3k	20	17	the	the	DT
cord-263699-gosqpg3k	20	18	plasma	plasma	NN
cord-263699-gosqpg3k	20	19	membrane	membrane	NN
cord-263699-gosqpg3k	20	20	,	,	,
cord-263699-gosqpg3k	20	21	as	as	RB
cord-263699-gosqpg3k	20	22	well	well	RB
cord-263699-gosqpg3k	20	23	as	as	IN
cord-263699-gosqpg3k	20	24	between	between	IN
cord-263699-gosqpg3k	20	25	the	the	DT
cord-263699-gosqpg3k	20	26	plasma	plasma	NN
cord-263699-gosqpg3k	20	27	membrane	membrane	NN
cord-263699-gosqpg3k	20	28	and	and	CC
cord-263699-gosqpg3k	20	29	endosomes	endosome	NNS
cord-263699-gosqpg3k	20	30	[	[	-LRB-
cord-263699-gosqpg3k	20	31	18	18	CD
cord-263699-gosqpg3k	20	32	]	]	-RRB-
cord-263699-gosqpg3k	21	1	(	(	-LRB-
cord-263699-gosqpg3k	21	2	Figure	figure	NN
cord-263699-gosqpg3k	21	3	1	1	CD
cord-263699-gosqpg3k	21	4	)	)	-RRB-
cord-263699-gosqpg3k	21	5	.	.	.
cord-263699-gosqpg3k	22	1	Recently	recently	RB
cord-263699-gosqpg3k	22	2	,	,	,
cord-263699-gosqpg3k	22	3	besides	besides	IN
cord-263699-gosqpg3k	22	4	its	-PRON-	PRP$
cord-263699-gosqpg3k	22	5	canonical	canonical	JJ
cord-263699-gosqpg3k	22	6	functions	function	NNS
cord-263699-gosqpg3k	22	7	in	in	IN
cord-263699-gosqpg3k	22	8	the	the	DT
cord-263699-gosqpg3k	22	9	secretory	secretory	JJ
cord-263699-gosqpg3k	22	10	pathway	pathway	NN
cord-263699-gosqpg3k	22	11	,	,	,
cord-263699-gosqpg3k	22	12	the	the	DT
cord-263699-gosqpg3k	22	13	COPI	COPI	NNP
cord-263699-gosqpg3k	22	14	machinery	machinery	NN
cord-263699-gosqpg3k	22	15	has	have	VBZ
cord-263699-gosqpg3k	22	16	been	be	VBN
cord-263699-gosqpg3k	22	17	shown	show	VBN
cord-263699-gosqpg3k	22	18	to	to	TO
cord-263699-gosqpg3k	22	19	participate	participate	VB
cord-263699-gosqpg3k	22	20	in	in	IN
cord-263699-gosqpg3k	22	21	the	the	DT
cord-263699-gosqpg3k	22	22	maturation	maturation	NN
cord-263699-gosqpg3k	22	23	of	of	IN
cord-263699-gosqpg3k	22	24	early	early	JJ
cord-263699-gosqpg3k	22	25	endosomes	endosome	NNS
cord-263699-gosqpg3k	22	26	and	and	CC
cord-263699-gosqpg3k	22	27	in	in	IN
cord-263699-gosqpg3k	22	28	recycling	recycling	NN
cord-263699-gosqpg3k	22	29	proteins	protein	NNS
cord-263699-gosqpg3k	22	30	to	to	IN
cord-263699-gosqpg3k	22	31	the	the	DT
cord-263699-gosqpg3k	22	32	plasma	plasma	NN
cord-263699-gosqpg3k	22	33	membrane	membrane	NN
cord-263699-gosqpg3k	22	34	[	[	-LRB-
cord-263699-gosqpg3k	22	35	19	19	CD
cord-263699-gosqpg3k	22	36	,	,	,
cord-263699-gosqpg3k	22	37	20	20	CD
cord-263699-gosqpg3k	22	38	]	]	-RRB-
cord-263699-gosqpg3k	22	39	,	,	,
cord-263699-gosqpg3k	22	40	as	as	RB
cord-263699-gosqpg3k	22	41	well	well	RB
cord-263699-gosqpg3k	22	42	as	as	IN
cord-263699-gosqpg3k	22	43	in	in	IN
cord-263699-gosqpg3k	22	44	the	the	DT
cord-263699-gosqpg3k	22	45	maturation	maturation	NN
cord-263699-gosqpg3k	22	46	of	of	IN
cord-263699-gosqpg3k	22	47	phagosomes	phagosomes	NNP
cord-263699-gosqpg3k	22	48	[	[	-LRB-
cord-263699-gosqpg3k	22	49	21	21	CD
cord-263699-gosqpg3k	22	50	,	,	,
cord-263699-gosqpg3k	22	51	22	22	CD
cord-263699-gosqpg3k	22	52	]	]	-RRB-
cord-263699-gosqpg3k	22	53	and	and	CC
cord-263699-gosqpg3k	22	54	peroxisomes	peroxisome	NNS
cord-263699-gosqpg3k	22	55	[	[	-LRB-
cord-263699-gosqpg3k	22	56	23	23	CD
cord-263699-gosqpg3k	22	57	]	]	-RRB-
cord-263699-gosqpg3k	22	58	.	.	.
cord-263699-gosqpg3k	23	1	Furthermore	furthermore	RB
cord-263699-gosqpg3k	23	2	,	,	,
cord-263699-gosqpg3k	23	3	multiple	multiple	JJ
cord-263699-gosqpg3k	23	4	reports	report	NNS
cord-263699-gosqpg3k	23	5	suggest	suggest	VBP
cord-263699-gosqpg3k	23	6	that	that	IN
cord-263699-gosqpg3k	23	7	COPI	COPI	NNP
cord-263699-gosqpg3k	23	8	-	-	HYPH
cord-263699-gosqpg3k	23	9	vesicles	vesicle	NNS
cord-263699-gosqpg3k	23	10	are	be	VBP
cord-263699-gosqpg3k	23	11	also	also	RB
cord-263699-gosqpg3k	23	12	involved	involve	VBN
cord-263699-gosqpg3k	23	13	in	in	IN
cord-263699-gosqpg3k	23	14	transport	transport	NN
cord-263699-gosqpg3k	23	15	events	event	NNS
cord-263699-gosqpg3k	23	16	related	relate	VBN
cord-263699-gosqpg3k	23	17	to	to	IN
cord-263699-gosqpg3k	23	18	the	the	DT
cord-263699-gosqpg3k	23	19	maturation	maturation	NN
cord-263699-gosqpg3k	23	20	and	and	CC
cord-263699-gosqpg3k	23	21	function	function	NN
cord-263699-gosqpg3k	23	22	of	of	IN
cord-263699-gosqpg3k	23	23	lipid	lipid	NN
cord-263699-gosqpg3k	23	24	droplets	droplet	NNS
cord-263699-gosqpg3k	23	25	(	(	-LRB-
cord-263699-gosqpg3k	23	26	LDs	LDs	NNP
cord-263699-gosqpg3k	23	27	)	)	-RRB-
cord-263699-gosqpg3k	24	1	[	[	-LRB-
cord-263699-gosqpg3k	24	2	24	24	CD
cord-263699-gosqpg3k	24	3	]	]	-RRB-
cord-263699-gosqpg3k	24	4	[	[	-LRB-
cord-263699-gosqpg3k	24	5	25	25	CD
cord-263699-gosqpg3k	24	6	]	]	-RRB-
cord-263699-gosqpg3k	24	7	[	[	-LRB-
cord-263699-gosqpg3k	24	8	26	26	CD
cord-263699-gosqpg3k	24	9	]	]	-RRB-
cord-263699-gosqpg3k	24	10	.	.	.
cord-263699-gosqpg3k	25	1	The	the	DT
cord-263699-gosqpg3k	25	2	mechanism	mechanism	NN
cord-263699-gosqpg3k	25	3	of	of	IN
cord-263699-gosqpg3k	25	4	COPI	COPI	NNP
cord-263699-gosqpg3k	25	5	vesicle	vesicle	NN
cord-263699-gosqpg3k	25	6	formation	formation	NN
cord-263699-gosqpg3k	25	7	is	be	VBZ
cord-263699-gosqpg3k	25	8	a	a	DT
cord-263699-gosqpg3k	25	9	complex	complex	JJ
cord-263699-gosqpg3k	25	10	process	process	NN
cord-263699-gosqpg3k	25	11	regulated	regulate	VBN
cord-263699-gosqpg3k	25	12	by	by	IN
cord-263699-gosqpg3k	25	13	the	the	DT
cord-263699-gosqpg3k	25	14	activation	activation	NN
cord-263699-gosqpg3k	25	15	of	of	IN
cord-263699-gosqpg3k	25	16	the	the	DT
cord-263699-gosqpg3k	25	17	small	small	JJ
cord-263699-gosqpg3k	25	18	GTPase	GTPase	NNP
cord-263699-gosqpg3k	25	19	Arf1	Arf1	NNP
cord-263699-gosqpg3k	25	20	(	(	-LRB-
cord-263699-gosqpg3k	25	21	ADP	adp	NN
cord-263699-gosqpg3k	25	22	-	-	HYPH
cord-263699-gosqpg3k	25	23	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	25	24	factor	factor	NN
cord-263699-gosqpg3k	25	25	1	1	CD
cord-263699-gosqpg3k	25	26	)	)	-RRB-
cord-263699-gosqpg3k	26	1	(	(	-LRB-
cord-263699-gosqpg3k	26	2	Figure	figure	NN
cord-263699-gosqpg3k	26	3	2	2	CD
cord-263699-gosqpg3k	26	4	)	)	-RRB-
cord-263699-gosqpg3k	26	5	.	.	.
cord-263699-gosqpg3k	27	1	This	this	DT
cord-263699-gosqpg3k	27	2	protein	protein	NN
cord-263699-gosqpg3k	27	3	belongs	belong	VBZ
cord-263699-gosqpg3k	27	4	to	to	IN
cord-263699-gosqpg3k	27	5	a	a	DT
cord-263699-gosqpg3k	27	6	family	family	NN
cord-263699-gosqpg3k	27	7	of	of	IN
cord-263699-gosqpg3k	27	8	low	low	JJ
cord-263699-gosqpg3k	27	9	molecular	molecular	JJ
cord-263699-gosqpg3k	27	10	weight	weight	NN
cord-263699-gosqpg3k	27	11	guanine	guanine	NN
cord-263699-gosqpg3k	27	12	-	-	HYPH
cord-263699-gosqpg3k	27	13	nucleotide	nucleotide	NN
cord-263699-gosqpg3k	27	14	-	-	HYPH
cord-263699-gosqpg3k	27	15	binding	bind	VBG
cord-263699-gosqpg3k	27	16	proteins	protein	NNS
cord-263699-gosqpg3k	27	17	that	that	WDT
cord-263699-gosqpg3k	27	18	can	can	MD
cord-263699-gosqpg3k	27	19	be	be	VB
cord-263699-gosqpg3k	27	20	divided	divide	VBN
cord-263699-gosqpg3k	27	21	into	into	IN
cord-263699-gosqpg3k	27	22	Arf	Arf	NNP
cord-263699-gosqpg3k	27	23	proteins	protein	NNS
cord-263699-gosqpg3k	27	24	of	of	IN
cord-263699-gosqpg3k	27	25	Class	class	NN
cord-263699-gosqpg3k	27	26	I	i	NN
cord-263699-gosqpg3k	27	27	(	(	-LRB-
cord-263699-gosqpg3k	27	28	Arf1	Arf1	NNP
cord-263699-gosqpg3k	27	29	,	,	,
cord-263699-gosqpg3k	27	30	Arf2	Arf2	NNP
cord-263699-gosqpg3k	27	31	,	,	,
cord-263699-gosqpg3k	27	32	and	and	CC
cord-263699-gosqpg3k	27	33	Arf3	Arf3	NNP
cord-263699-gosqpg3k	27	34	)	)	-RRB-
cord-263699-gosqpg3k	27	35	,	,	,
cord-263699-gosqpg3k	27	36	Class	Class	NNP
cord-263699-gosqpg3k	27	37	II	II	NNP
cord-263699-gosqpg3k	27	38	(	(	-LRB-
cord-263699-gosqpg3k	27	39	Arf4	Arf4	NNP
cord-263699-gosqpg3k	27	40	and	and	CC
cord-263699-gosqpg3k	27	41	Arf5	Arf5	NNP
cord-263699-gosqpg3k	27	42	)	)	-RRB-
cord-263699-gosqpg3k	27	43	and	and	CC
cord-263699-gosqpg3k	27	44	Class	Class	NNP
cord-263699-gosqpg3k	27	45	III	III	NNP
cord-263699-gosqpg3k	27	46	(	(	-LRB-
cord-263699-gosqpg3k	27	47	Arf6	Arf6	NNP
cord-263699-gosqpg3k	27	48	)	)	-RRB-
cord-263699-gosqpg3k	27	49	,	,	,
cord-263699-gosqpg3k	27	50	depending	depend	VBG
cord-263699-gosqpg3k	27	51	on	on	IN
cord-263699-gosqpg3k	27	52	their	-PRON-	PRP$
cord-263699-gosqpg3k	27	53	sequence	sequence	NN
cord-263699-gosqpg3k	27	54	identity	identity	NN
cord-263699-gosqpg3k	27	55	.	.	.
cord-263699-gosqpg3k	28	1	Arf	Arf	NNP
cord-263699-gosqpg3k	28	2	proteins	protein	NNS
cord-263699-gosqpg3k	28	3	cycle	cycle	VBP
cord-263699-gosqpg3k	28	4	between	between	IN
cord-263699-gosqpg3k	28	5	an	an	DT
cord-263699-gosqpg3k	28	6	inactivated	inactivate	VBN
cord-263699-gosqpg3k	28	7	cytosolic	cytosolic	JJ
cord-263699-gosqpg3k	28	8	form	form	NN
cord-263699-gosqpg3k	28	9	,	,	,
cord-263699-gosqpg3k	28	10	bound	bind	VBN
cord-263699-gosqpg3k	28	11	to	to	IN
cord-263699-gosqpg3k	28	12	GDP	GDP	NNP
cord-263699-gosqpg3k	28	13	,	,	,
cord-263699-gosqpg3k	28	14	and	and	CC
cord-263699-gosqpg3k	28	15	an	an	DT
cord-263699-gosqpg3k	28	16	active	active	JJ
cord-263699-gosqpg3k	28	17	membrane	membrane	NN
cord-263699-gosqpg3k	28	18	-	-	HYPH
cord-263699-gosqpg3k	28	19	associated	associate	VBN
cord-263699-gosqpg3k	28	20	state	state	NN
cord-263699-gosqpg3k	28	21	,	,	,
cord-263699-gosqpg3k	28	22	when	when	WRB
cord-263699-gosqpg3k	28	23	bound	bind	VBN
cord-263699-gosqpg3k	28	24	to	to	IN
cord-263699-gosqpg3k	28	25	GTP	GTP	NNP
cord-263699-gosqpg3k	28	26	.	.	.
cord-263699-gosqpg3k	29	1	Arf	Arf	NNP
cord-263699-gosqpg3k	29	2	proteins	protein	NNS
cord-263699-gosqpg3k	29	3	are	be	VBP
cord-263699-gosqpg3k	29	4	highly	highly	RB
cord-263699-gosqpg3k	29	5	conserved	conserve	VBN
cord-263699-gosqpg3k	29	6	and	and	CC
cord-263699-gosqpg3k	29	7	are	be	VBP
cord-263699-gosqpg3k	29	8	present	present	JJ
cord-263699-gosqpg3k	29	9	in	in	IN
cord-263699-gosqpg3k	29	10	all	all	DT
cord-263699-gosqpg3k	29	11	eukaryotes	eukaryote	NNS
cord-263699-gosqpg3k	29	12	examined	examine	VBN
cord-263699-gosqpg3k	29	13	to	to	IN
cord-263699-gosqpg3k	29	14	date	date	NN
cord-263699-gosqpg3k	29	15	,	,	,
cord-263699-gosqpg3k	29	16	except	except	IN
cord-263699-gosqpg3k	29	17	for	for	IN
cord-263699-gosqpg3k	29	18	Arf2	Arf2	NNP
cord-263699-gosqpg3k	29	19	,	,	,
cord-263699-gosqpg3k	29	20	which	which	WDT
cord-263699-gosqpg3k	29	21	has	have	VBZ
cord-263699-gosqpg3k	29	22	not	not	RB
cord-263699-gosqpg3k	29	23	been	be	VBN
cord-263699-gosqpg3k	29	24	reported	report	VBN
cord-263699-gosqpg3k	29	25	to	to	TO
cord-263699-gosqpg3k	29	26	be	be	VB
cord-263699-gosqpg3k	29	27	present	present	JJ
cord-263699-gosqpg3k	29	28	in	in	IN
cord-263699-gosqpg3k	29	29	humans	human	NNS
cord-263699-gosqpg3k	29	30	.	.	.
cord-263699-gosqpg3k	30	1	These	these	DT
cord-263699-gosqpg3k	30	2	proteins	protein	NNS
cord-263699-gosqpg3k	30	3	have	have	VBP
cord-263699-gosqpg3k	30	4	been	be	VBN
cord-263699-gosqpg3k	30	5	shown	show	VBN
cord-263699-gosqpg3k	30	6	to	to	TO
cord-263699-gosqpg3k	30	7	play	play	VB
cord-263699-gosqpg3k	30	8	a	a	DT
cord-263699-gosqpg3k	30	9	number	number	NN
cord-263699-gosqpg3k	30	10	of	of	IN
cord-263699-gosqpg3k	30	11	regulatory	regulatory	JJ
cord-263699-gosqpg3k	30	12	roles	role	NNS
cord-263699-gosqpg3k	30	13	related	relate	VBN
cord-263699-gosqpg3k	30	14	not	not	RB
cord-263699-gosqpg3k	30	15	only	only	RB
cord-263699-gosqpg3k	30	16	with	with	IN
cord-263699-gosqpg3k	30	17	membrane	membrane	NN
cord-263699-gosqpg3k	30	18	traffic	traffic	NN
cord-263699-gosqpg3k	30	19	,	,	,
cord-263699-gosqpg3k	30	20	but	but	CC
cord-263699-gosqpg3k	30	21	in	in	IN
cord-263699-gosqpg3k	30	22	lipid	lipid	NN
cord-263699-gosqpg3k	30	23	metabolism	metabolism	NN
cord-263699-gosqpg3k	30	24	,	,	,
cord-263699-gosqpg3k	30	25	organelle	organelle	NN
cord-263699-gosqpg3k	30	26	morphology	morphology	NN
cord-263699-gosqpg3k	30	27	,	,	,
cord-263699-gosqpg3k	30	28	and	and	CC
cord-263699-gosqpg3k	30	29	cellular	cellular	JJ
cord-263699-gosqpg3k	30	30	signaling	signal	VBG
cord-263699-gosqpg3k	30	31	[	[	-LRB-
cord-263699-gosqpg3k	30	32	27	27	CD
cord-263699-gosqpg3k	30	33	]	]	-RRB-
cord-263699-gosqpg3k	30	34	[	[	-LRB-
cord-263699-gosqpg3k	30	35	28	28	CD
cord-263699-gosqpg3k	30	36	]	]	-RRB-
cord-263699-gosqpg3k	30	37	[	[	-LRB-
cord-263699-gosqpg3k	30	38	29	29	CD
cord-263699-gosqpg3k	30	39	]	]	-RRB-
cord-263699-gosqpg3k	30	40	.	.	.
cord-263699-gosqpg3k	31	1	Given	give	VBN
cord-263699-gosqpg3k	31	2	that	that	IN
cord-263699-gosqpg3k	31	3	Arf1	Arf1	NNP
cord-263699-gosqpg3k	31	4	and	and	CC
cord-263699-gosqpg3k	31	5	Arf3	Arf3	NNP
cord-263699-gosqpg3k	31	6	are	be	VBP
cord-263699-gosqpg3k	31	7	the	the	DT
cord-263699-gosqpg3k	31	8	most	most	RBS
cord-263699-gosqpg3k	31	9	abundantly	abundantly	RB
cord-263699-gosqpg3k	31	10	expressed	express	VBN
cord-263699-gosqpg3k	31	11	Arf	Arf	NNP
cord-263699-gosqpg3k	31	12	isoforms	isoform	NNS
cord-263699-gosqpg3k	31	13	in	in	IN
cord-263699-gosqpg3k	31	14	cells	cell	NNS
cord-263699-gosqpg3k	31	15	,	,	,
cord-263699-gosqpg3k	31	16	Class	class	NN
cord-263699-gosqpg3k	31	17	I	-PRON-	PRP
cord-263699-gosqpg3k	31	18	Arfs	Arfs	NNP
cord-263699-gosqpg3k	31	19	have	have	VBP
cord-263699-gosqpg3k	31	20	been	be	VBN
cord-263699-gosqpg3k	31	21	assumed	assume	VBN
cord-263699-gosqpg3k	31	22	as	as	IN
cord-263699-gosqpg3k	31	23	the	the	DT
cord-263699-gosqpg3k	31	24	principal	principal	JJ
cord-263699-gosqpg3k	31	25	actors	actor	NNS
cord-263699-gosqpg3k	31	26	in	in	IN
cord-263699-gosqpg3k	31	27	vesicle	vesicle	NN
cord-263699-gosqpg3k	31	28	transport	transport	NN
cord-263699-gosqpg3k	31	29	.	.	.
cord-263699-gosqpg3k	32	1	However	however	RB
cord-263699-gosqpg3k	32	2	,	,	,
cord-263699-gosqpg3k	32	3	in	in	IN
cord-263699-gosqpg3k	32	4	recent	recent	JJ
cord-263699-gosqpg3k	32	5	years	year	NNS
cord-263699-gosqpg3k	32	6	it	-PRON-	PRP
cord-263699-gosqpg3k	32	7	has	have	VBZ
cord-263699-gosqpg3k	32	8	been	be	VBN
cord-263699-gosqpg3k	32	9	demonstrated	demonstrate	VBN
cord-263699-gosqpg3k	32	10	that	that	IN
cord-263699-gosqpg3k	32	11	although	although	IN
cord-263699-gosqpg3k	32	12	the	the	DT
cord-263699-gosqpg3k	32	13	different	different	JJ
cord-263699-gosqpg3k	32	14	Arf	Arf	NNP
cord-263699-gosqpg3k	32	15	proteins	protein	NNS
cord-263699-gosqpg3k	32	16	play	play	VBP
cord-263699-gosqpg3k	32	17	overlapping	overlapping	JJ
cord-263699-gosqpg3k	32	18	and	and	CC
cord-263699-gosqpg3k	32	19	redundant	redundant	JJ
cord-263699-gosqpg3k	32	20	roles	role	NNS
cord-263699-gosqpg3k	32	21	in	in	IN
cord-263699-gosqpg3k	32	22	cell	cell	NN
cord-263699-gosqpg3k	32	23	transport	transport	NN
cord-263699-gosqpg3k	32	24	,	,	,
cord-263699-gosqpg3k	32	25	specific	specific	JJ
cord-263699-gosqpg3k	32	26	Arfs	Arfs	NNP
cord-263699-gosqpg3k	32	27	display	display	VB
cord-263699-gosqpg3k	32	28	a	a	DT
cord-263699-gosqpg3k	32	29	unique	unique	JJ
cord-263699-gosqpg3k	32	30	profile	profile	NN
cord-263699-gosqpg3k	32	31	of	of	IN
cord-263699-gosqpg3k	32	32	activities	activity	NNS
cord-263699-gosqpg3k	32	33	to	to	TO
cord-263699-gosqpg3k	32	34	control	control	VB
cord-263699-gosqpg3k	32	35	specific	specific	JJ
cord-263699-gosqpg3k	32	36	points	point	NNS
cord-263699-gosqpg3k	32	37	in	in	IN
cord-263699-gosqpg3k	32	38	the	the	DT
cord-263699-gosqpg3k	32	39	secretory	secretory	JJ
cord-263699-gosqpg3k	32	40	and	and	CC
cord-263699-gosqpg3k	32	41	endocytic	endocytic	JJ
cord-263699-gosqpg3k	32	42	pathways	pathway	NNS
cord-263699-gosqpg3k	32	43	.	.	.
cord-263699-gosqpg3k	33	1	In	in	IN
cord-263699-gosqpg3k	33	2	addition	addition	NN
cord-263699-gosqpg3k	33	3	,	,	,
cord-263699-gosqpg3k	33	4	it	-PRON-	PRP
cord-263699-gosqpg3k	33	5	has	have	VBZ
cord-263699-gosqpg3k	33	6	also	also	RB
cord-263699-gosqpg3k	33	7	been	be	VBN
cord-263699-gosqpg3k	33	8	observed	observe	VBN
cord-263699-gosqpg3k	33	9	that	that	IN
cord-263699-gosqpg3k	33	10	in	in	IN
cord-263699-gosqpg3k	33	11	some	some	DT
cord-263699-gosqpg3k	33	12	cases	case	NNS
cord-263699-gosqpg3k	33	13	the	the	DT
cord-263699-gosqpg3k	33	14	control	control	NN
cord-263699-gosqpg3k	33	15	of	of	IN
cord-263699-gosqpg3k	33	16	vesicle	vesicle	NN
cord-263699-gosqpg3k	33	17	transport	transport	NN
cord-263699-gosqpg3k	33	18	can	can	MD
cord-263699-gosqpg3k	33	19	depend	depend	VB
cord-263699-gosqpg3k	33	20	on	on	IN
cord-263699-gosqpg3k	33	21	the	the	DT
cord-263699-gosqpg3k	33	22	cooperation	cooperation	NN
cord-263699-gosqpg3k	33	23	of	of	IN
cord-263699-gosqpg3k	33	24	two	two	CD
cord-263699-gosqpg3k	33	25	particular	particular	JJ
cord-263699-gosqpg3k	33	26	Arfs	Arfs	NNP
cord-263699-gosqpg3k	33	27	[	[	-LRB-
cord-263699-gosqpg3k	33	28	30	30	CD
cord-263699-gosqpg3k	33	29	]	]	-RRB-
cord-263699-gosqpg3k	33	30	.	.	.
cord-263699-gosqpg3k	34	1	The	the	DT
cord-263699-gosqpg3k	34	2	mechanism	mechanism	NN
cord-263699-gosqpg3k	34	3	of	of	IN
cord-263699-gosqpg3k	34	4	COPI	COPI	NNP
cord-263699-gosqpg3k	34	5	vesicle	vesicle	NN
cord-263699-gosqpg3k	34	6	formation	formation	NN
cord-263699-gosqpg3k	34	7	is	be	VBZ
cord-263699-gosqpg3k	34	8	a	a	DT
cord-263699-gosqpg3k	34	9	complex	complex	JJ
cord-263699-gosqpg3k	34	10	process	process	NN
cord-263699-gosqpg3k	34	11	regulated	regulate	VBN
cord-263699-gosqpg3k	34	12	by	by	IN
cord-263699-gosqpg3k	34	13	the	the	DT
cord-263699-gosqpg3k	34	14	activation	activation	NN
cord-263699-gosqpg3k	34	15	of	of	IN
cord-263699-gosqpg3k	34	16	the	the	DT
cord-263699-gosqpg3k	34	17	small	small	JJ
cord-263699-gosqpg3k	34	18	GTPase	GTPase	NNP
cord-263699-gosqpg3k	34	19	Arf1	Arf1	NNP
cord-263699-gosqpg3k	34	20	(	(	-LRB-
cord-263699-gosqpg3k	34	21	ADP	adp	NN
cord-263699-gosqpg3k	34	22	-	-	HYPH
cord-263699-gosqpg3k	34	23	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	34	24	factor	factor	NN
cord-263699-gosqpg3k	34	25	1	1	CD
cord-263699-gosqpg3k	34	26	)	)	-RRB-
cord-263699-gosqpg3k	35	1	(	(	-LRB-
cord-263699-gosqpg3k	35	2	Figure	figure	NN
cord-263699-gosqpg3k	35	3	2	2	CD
cord-263699-gosqpg3k	35	4	)	)	-RRB-
cord-263699-gosqpg3k	35	5	.	.	.
cord-263699-gosqpg3k	36	1	This	this	DT
cord-263699-gosqpg3k	36	2	protein	protein	NN
cord-263699-gosqpg3k	36	3	belongs	belong	VBZ
cord-263699-gosqpg3k	36	4	to	to	IN
cord-263699-gosqpg3k	36	5	a	a	DT
cord-263699-gosqpg3k	36	6	family	family	NN
cord-263699-gosqpg3k	36	7	of	of	IN
cord-263699-gosqpg3k	36	8	low	low	JJ
cord-263699-gosqpg3k	36	9	molecular	molecular	JJ
cord-263699-gosqpg3k	36	10	weight	weight	NN
cord-263699-gosqpg3k	36	11	guanine	guanine	NN
cord-263699-gosqpg3k	36	12	-	-	HYPH
cord-263699-gosqpg3k	36	13	nucleotide	nucleotide	NN
cord-263699-gosqpg3k	36	14	-	-	HYPH
cord-263699-gosqpg3k	36	15	binding	bind	VBG
cord-263699-gosqpg3k	36	16	proteins	protein	NNS
cord-263699-gosqpg3k	36	17	that	that	WDT
cord-263699-gosqpg3k	36	18	can	can	MD
cord-263699-gosqpg3k	36	19	be	be	VB
cord-263699-gosqpg3k	36	20	divided	divide	VBN
cord-263699-gosqpg3k	36	21	into	into	IN
cord-263699-gosqpg3k	36	22	Arf	Arf	NNP
cord-263699-gosqpg3k	36	23	proteins	protein	NNS
cord-263699-gosqpg3k	36	24	of	of	IN
cord-263699-gosqpg3k	36	25	Class	class	NN
cord-263699-gosqpg3k	36	26	I	i	NN
cord-263699-gosqpg3k	36	27	(	(	-LRB-
cord-263699-gosqpg3k	36	28	Arf1	Arf1	NNP
cord-263699-gosqpg3k	36	29	,	,	,
cord-263699-gosqpg3k	36	30	Arf2	Arf2	NNP
cord-263699-gosqpg3k	36	31	,	,	,
cord-263699-gosqpg3k	36	32	and	and	CC
cord-263699-gosqpg3k	36	33	Arf3	Arf3	NNP
cord-263699-gosqpg3k	36	34	)	)	-RRB-
cord-263699-gosqpg3k	36	35	,	,	,
cord-263699-gosqpg3k	36	36	Class	Class	NNP
cord-263699-gosqpg3k	36	37	II	II	NNP
cord-263699-gosqpg3k	36	38	(	(	-LRB-
cord-263699-gosqpg3k	36	39	Arf4	Arf4	NNP
cord-263699-gosqpg3k	36	40	and	and	CC
cord-263699-gosqpg3k	36	41	Arf5	Arf5	NNP
cord-263699-gosqpg3k	36	42	)	)	-RRB-
cord-263699-gosqpg3k	36	43	and	and	CC
cord-263699-gosqpg3k	36	44	Class	Class	NNP
cord-263699-gosqpg3k	36	45	III	III	NNP
cord-263699-gosqpg3k	36	46	(	(	-LRB-
cord-263699-gosqpg3k	36	47	Arf6	Arf6	NNP
cord-263699-gosqpg3k	36	48	)	)	-RRB-
cord-263699-gosqpg3k	36	49	,	,	,
cord-263699-gosqpg3k	36	50	depending	depend	VBG
cord-263699-gosqpg3k	36	51	on	on	IN
cord-263699-gosqpg3k	36	52	their	-PRON-	PRP$
cord-263699-gosqpg3k	36	53	sequence	sequence	NN
cord-263699-gosqpg3k	36	54	identity	identity	NN
cord-263699-gosqpg3k	36	55	.	.	.
cord-263699-gosqpg3k	37	1	Arf	Arf	NNP
cord-263699-gosqpg3k	37	2	proteins	protein	NNS
cord-263699-gosqpg3k	37	3	cycle	cycle	VBP
cord-263699-gosqpg3k	37	4	between	between	IN
cord-263699-gosqpg3k	37	5	an	an	DT
cord-263699-gosqpg3k	37	6	inactivated	inactivate	VBN
cord-263699-gosqpg3k	37	7	cytosolic	cytosolic	JJ
cord-263699-gosqpg3k	37	8	form	form	NN
cord-263699-gosqpg3k	37	9	,	,	,
cord-263699-gosqpg3k	37	10	bound	bind	VBN
cord-263699-gosqpg3k	37	11	to	to	IN
cord-263699-gosqpg3k	37	12	GDP	GDP	NNP
cord-263699-gosqpg3k	37	13	,	,	,
cord-263699-gosqpg3k	37	14	and	and	CC
cord-263699-gosqpg3k	37	15	an	an	DT
cord-263699-gosqpg3k	37	16	active	active	JJ
cord-263699-gosqpg3k	37	17	membrane	membrane	NN
cord-263699-gosqpg3k	37	18	-	-	HYPH
cord-263699-gosqpg3k	37	19	associated	associate	VBN
cord-263699-gosqpg3k	37	20	state	state	NN
cord-263699-gosqpg3k	37	21	,	,	,
cord-263699-gosqpg3k	37	22	when	when	WRB
cord-263699-gosqpg3k	37	23	bound	bind	VBN
cord-263699-gosqpg3k	37	24	to	to	IN
cord-263699-gosqpg3k	37	25	GTP	GTP	NNP
cord-263699-gosqpg3k	37	26	.	.	.
cord-263699-gosqpg3k	38	1	Arf	Arf	NNP
cord-263699-gosqpg3k	38	2	proteins	protein	NNS
cord-263699-gosqpg3k	38	3	are	be	VBP
cord-263699-gosqpg3k	38	4	highly	highly	RB
cord-263699-gosqpg3k	38	5	conserved	conserve	VBN
cord-263699-gosqpg3k	38	6	and	and	CC
cord-263699-gosqpg3k	38	7	are	be	VBP
cord-263699-gosqpg3k	38	8	present	present	JJ
cord-263699-gosqpg3k	38	9	in	in	IN
cord-263699-gosqpg3k	38	10	all	all	DT
cord-263699-gosqpg3k	38	11	eukaryotes	eukaryote	NNS
cord-263699-gosqpg3k	38	12	examined	examine	VBN
cord-263699-gosqpg3k	38	13	to	to	IN
cord-263699-gosqpg3k	38	14	date	date	NN
cord-263699-gosqpg3k	38	15	,	,	,
cord-263699-gosqpg3k	38	16	except	except	IN
cord-263699-gosqpg3k	38	17	for	for	IN
cord-263699-gosqpg3k	38	18	Arf2	Arf2	NNP
cord-263699-gosqpg3k	38	19	,	,	,
cord-263699-gosqpg3k	38	20	which	which	WDT
cord-263699-gosqpg3k	38	21	has	have	VBZ
cord-263699-gosqpg3k	38	22	not	not	RB
cord-263699-gosqpg3k	38	23	been	be	VBN
cord-263699-gosqpg3k	38	24	reported	report	VBN
cord-263699-gosqpg3k	38	25	to	to	TO
cord-263699-gosqpg3k	38	26	be	be	VB
cord-263699-gosqpg3k	38	27	present	present	JJ
cord-263699-gosqpg3k	38	28	in	in	IN
cord-263699-gosqpg3k	38	29	humans	human	NNS
cord-263699-gosqpg3k	38	30	.	.	.
cord-263699-gosqpg3k	39	1	These	these	DT
cord-263699-gosqpg3k	39	2	proteins	protein	NNS
cord-263699-gosqpg3k	39	3	have	have	VBP
cord-263699-gosqpg3k	39	4	been	be	VBN
cord-263699-gosqpg3k	39	5	shown	show	VBN
cord-263699-gosqpg3k	39	6	to	to	TO
cord-263699-gosqpg3k	39	7	play	play	VB
cord-263699-gosqpg3k	39	8	a	a	DT
cord-263699-gosqpg3k	39	9	number	number	NN
cord-263699-gosqpg3k	39	10	of	of	IN
cord-263699-gosqpg3k	39	11	regulatory	regulatory	JJ
cord-263699-gosqpg3k	39	12	roles	role	NNS
cord-263699-gosqpg3k	39	13	related	relate	VBN
cord-263699-gosqpg3k	39	14	not	not	RB
cord-263699-gosqpg3k	39	15	only	only	RB
cord-263699-gosqpg3k	39	16	with	with	IN
cord-263699-gosqpg3k	39	17	membrane	membrane	NN
cord-263699-gosqpg3k	39	18	traffic	traffic	NN
cord-263699-gosqpg3k	39	19	,	,	,
cord-263699-gosqpg3k	39	20	but	but	CC
cord-263699-gosqpg3k	39	21	in	in	IN
cord-263699-gosqpg3k	39	22	lipid	lipid	NN
cord-263699-gosqpg3k	39	23	metabolism	metabolism	NN
cord-263699-gosqpg3k	39	24	,	,	,
cord-263699-gosqpg3k	39	25	organelle	organelle	NN
cord-263699-gosqpg3k	39	26	morphology	morphology	NN
cord-263699-gosqpg3k	39	27	,	,	,
cord-263699-gosqpg3k	39	28	and	and	CC
cord-263699-gosqpg3k	39	29	cellular	cellular	JJ
cord-263699-gosqpg3k	39	30	signaling	signal	VBG
cord-263699-gosqpg3k	39	31	[	[	-LRB-
cord-263699-gosqpg3k	39	32	27	27	CD
cord-263699-gosqpg3k	39	33	]	]	-RRB-
cord-263699-gosqpg3k	39	34	[	[	-LRB-
cord-263699-gosqpg3k	39	35	28	28	CD
cord-263699-gosqpg3k	39	36	]	]	-RRB-
cord-263699-gosqpg3k	39	37	[	[	-LRB-
cord-263699-gosqpg3k	39	38	29	29	CD
cord-263699-gosqpg3k	39	39	]	]	-RRB-
cord-263699-gosqpg3k	39	40	.	.	.
cord-263699-gosqpg3k	40	1	Given	give	VBN
cord-263699-gosqpg3k	40	2	that	that	IN
cord-263699-gosqpg3k	40	3	Arf1	Arf1	NNP
cord-263699-gosqpg3k	40	4	and	and	CC
cord-263699-gosqpg3k	40	5	Arf3	Arf3	NNP
cord-263699-gosqpg3k	40	6	are	be	VBP
cord-263699-gosqpg3k	40	7	the	the	DT
cord-263699-gosqpg3k	40	8	most	most	RBS
cord-263699-gosqpg3k	40	9	abundantly	abundantly	RB
cord-263699-gosqpg3k	40	10	expressed	express	VBN
cord-263699-gosqpg3k	40	11	Arf	Arf	NNP
cord-263699-gosqpg3k	40	12	isoforms	isoform	NNS
cord-263699-gosqpg3k	40	13	in	in	IN
cord-263699-gosqpg3k	40	14	cells	cell	NNS
cord-263699-gosqpg3k	40	15	,	,	,
cord-263699-gosqpg3k	40	16	Class	class	NN
cord-263699-gosqpg3k	40	17	I	-PRON-	PRP
cord-263699-gosqpg3k	40	18	Arfs	Arfs	NNP
cord-263699-gosqpg3k	40	19	have	have	VBP
cord-263699-gosqpg3k	40	20	been	be	VBN
cord-263699-gosqpg3k	40	21	assumed	assume	VBN
cord-263699-gosqpg3k	40	22	as	as	IN
cord-263699-gosqpg3k	40	23	the	the	DT
cord-263699-gosqpg3k	40	24	principal	principal	JJ
cord-263699-gosqpg3k	40	25	actors	actor	NNS
cord-263699-gosqpg3k	40	26	in	in	IN
cord-263699-gosqpg3k	40	27	vesicle	vesicle	NN
cord-263699-gosqpg3k	40	28	transport	transport	NN
cord-263699-gosqpg3k	40	29	.	.	.
cord-263699-gosqpg3k	41	1	However	however	RB
cord-263699-gosqpg3k	41	2	,	,	,
cord-263699-gosqpg3k	41	3	in	in	IN
cord-263699-gosqpg3k	41	4	recent	recent	JJ
cord-263699-gosqpg3k	41	5	years	year	NNS
cord-263699-gosqpg3k	41	6	it	-PRON-	PRP
cord-263699-gosqpg3k	41	7	has	have	VBZ
cord-263699-gosqpg3k	41	8	been	be	VBN
cord-263699-gosqpg3k	41	9	demonstrated	demonstrate	VBN
cord-263699-gosqpg3k	41	10	that	that	IN
cord-263699-gosqpg3k	41	11	although	although	IN
cord-263699-gosqpg3k	41	12	the	the	DT
cord-263699-gosqpg3k	41	13	different	different	JJ
cord-263699-gosqpg3k	41	14	Arf	Arf	NNP
cord-263699-gosqpg3k	41	15	proteins	protein	NNS
cord-263699-gosqpg3k	41	16	play	play	VBP
cord-263699-gosqpg3k	41	17	overlapping	overlapping	JJ
cord-263699-gosqpg3k	41	18	and	and	CC
cord-263699-gosqpg3k	41	19	redundant	redundant	JJ
cord-263699-gosqpg3k	41	20	roles	role	NNS
cord-263699-gosqpg3k	41	21	in	in	IN
cord-263699-gosqpg3k	41	22	cell	cell	NN
cord-263699-gosqpg3k	41	23	transport	transport	NN
cord-263699-gosqpg3k	41	24	,	,	,
cord-263699-gosqpg3k	41	25	specific	specific	JJ
cord-263699-gosqpg3k	41	26	Arfs	Arfs	NNP
cord-263699-gosqpg3k	41	27	display	display	VB
cord-263699-gosqpg3k	41	28	a	a	DT
cord-263699-gosqpg3k	41	29	unique	unique	JJ
cord-263699-gosqpg3k	41	30	profile	profile	NN
cord-263699-gosqpg3k	41	31	of	of	IN
cord-263699-gosqpg3k	41	32	activities	activity	NNS
cord-263699-gosqpg3k	41	33	to	to	TO
cord-263699-gosqpg3k	41	34	control	control	VB
cord-263699-gosqpg3k	41	35	specific	specific	JJ
cord-263699-gosqpg3k	41	36	points	point	NNS
cord-263699-gosqpg3k	41	37	in	in	IN
cord-263699-gosqpg3k	41	38	the	the	DT
cord-263699-gosqpg3k	41	39	secretory	secretory	JJ
cord-263699-gosqpg3k	41	40	and	and	CC
cord-263699-gosqpg3k	41	41	endocytic	endocytic	JJ
cord-263699-gosqpg3k	41	42	pathways	pathway	NNS
cord-263699-gosqpg3k	41	43	.	.	.
cord-263699-gosqpg3k	42	1	In	in	IN
cord-263699-gosqpg3k	42	2	addition	addition	NN
cord-263699-gosqpg3k	42	3	,	,	,
cord-263699-gosqpg3k	42	4	it	-PRON-	PRP
cord-263699-gosqpg3k	42	5	has	have	VBZ
cord-263699-gosqpg3k	42	6	also	also	RB
cord-263699-gosqpg3k	42	7	been	be	VBN
cord-263699-gosqpg3k	42	8	observed	observe	VBN
cord-263699-gosqpg3k	42	9	that	that	IN
cord-263699-gosqpg3k	42	10	in	in	IN
cord-263699-gosqpg3k	42	11	some	some	DT
cord-263699-gosqpg3k	42	12	cases	case	NNS
cord-263699-gosqpg3k	42	13	the	the	DT
cord-263699-gosqpg3k	42	14	control	control	NN
cord-263699-gosqpg3k	42	15	of	of	IN
cord-263699-gosqpg3k	42	16	vesicle	vesicle	NN
cord-263699-gosqpg3k	42	17	transport	transport	NN
cord-263699-gosqpg3k	42	18	can	can	MD
cord-263699-gosqpg3k	42	19	depend	depend	VB
cord-263699-gosqpg3k	42	20	on	on	IN
cord-263699-gosqpg3k	42	21	the	the	DT
cord-263699-gosqpg3k	42	22	cooperation	cooperation	NN
cord-263699-gosqpg3k	42	23	of	of	IN
cord-263699-gosqpg3k	42	24	two	two	CD
cord-263699-gosqpg3k	42	25	particular	particular	JJ
cord-263699-gosqpg3k	42	26	Arfs	Arfs	NNP
cord-263699-gosqpg3k	42	27	[	[	-LRB-
cord-263699-gosqpg3k	42	28	30	30	CD
cord-263699-gosqpg3k	42	29	]	]	-RRB-
cord-263699-gosqpg3k	42	30	.	.	.
cord-263699-gosqpg3k	43	1	Mechanism	mechanism	NN
cord-263699-gosqpg3k	43	2	of	of	IN
cord-263699-gosqpg3k	43	3	COPI	COPI	NNP
cord-263699-gosqpg3k	43	4	transport	transport	NN
cord-263699-gosqpg3k	43	5	.	.	.
cord-263699-gosqpg3k	44	1	COPI	COPI	NNP
cord-263699-gosqpg3k	44	2	vesicle	vesicle	NN
cord-263699-gosqpg3k	44	3	formation	formation	NN
cord-263699-gosqpg3k	44	4	starts	start	VBZ
cord-263699-gosqpg3k	44	5	when	when	WRB
cord-263699-gosqpg3k	44	6	the	the	DT
cord-263699-gosqpg3k	44	7	small	small	JJ
cord-263699-gosqpg3k	44	8	GTPase	GTPase	NNP
cord-263699-gosqpg3k	44	9	Arf1	Arf1	NNP
cord-263699-gosqpg3k	44	10	,	,	,
cord-263699-gosqpg3k	44	11	bound	bind	VBN
cord-263699-gosqpg3k	44	12	to	to	IN
cord-263699-gosqpg3k	44	13	GDP	GDP	NNP
cord-263699-gosqpg3k	44	14	(	(	-LRB-
cord-263699-gosqpg3k	44	15	Arf1-GDP	Arf1-GDP	NNP
cord-263699-gosqpg3k	44	16	)	)	-RRB-
cord-263699-gosqpg3k	44	17	,	,	,
cord-263699-gosqpg3k	44	18	associates	associate	NNS
cord-263699-gosqpg3k	44	19	with	with	IN
cord-263699-gosqpg3k	44	20	the	the	DT
cord-263699-gosqpg3k	44	21	Golgi	Golgi	NNP
cord-263699-gosqpg3k	44	22	-	-	HYPH
cord-263699-gosqpg3k	44	23	specific	specific	JJ
cord-263699-gosqpg3k	44	24	Brefeldin	Brefeldin	NNP
cord-263699-gosqpg3k	44	25	A	A	NNP
cord-263699-gosqpg3k	44	26	(	(	-LRB-
cord-263699-gosqpg3k	44	27	BFA	BFA	NNP
cord-263699-gosqpg3k	44	28	)	)	-RRB-
cord-263699-gosqpg3k	44	29	resistance	resistance	NN
cord-263699-gosqpg3k	44	30	factor	factor	NN
cord-263699-gosqpg3k	44	31	1	1	CD
cord-263699-gosqpg3k	44	32	(	(	-LRB-
cord-263699-gosqpg3k	44	33	GBF1	GBF1	NNP
cord-263699-gosqpg3k	44	34	)	)	-RRB-
cord-263699-gosqpg3k	44	35	,	,	,
cord-263699-gosqpg3k	44	36	a	a	DT
cord-263699-gosqpg3k	44	37	guanine	guanine	NN
cord-263699-gosqpg3k	44	38	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	44	39	exchange	exchange	NN
cord-263699-gosqpg3k	44	40	factor	factor	NN
cord-263699-gosqpg3k	44	41	(	(	-LRB-
cord-263699-gosqpg3k	44	42	GEF	GEF	NNP
cord-263699-gosqpg3k	44	43	)	)	-RRB-
cord-263699-gosqpg3k	44	44	that	that	WDT
cord-263699-gosqpg3k	44	45	catalyzes	catalyze	VBZ
cord-263699-gosqpg3k	44	46	the	the	DT
cord-263699-gosqpg3k	44	47	activation	activation	NN
cord-263699-gosqpg3k	44	48	of	of	IN
cord-263699-gosqpg3k	44	49	Arf1	Arf1	NNP
cord-263699-gosqpg3k	44	50	by	by	IN
cord-263699-gosqpg3k	44	51	promoting	promote	VBG
cord-263699-gosqpg3k	44	52	the	the	DT
cord-263699-gosqpg3k	44	53	exchange	exchange	NN
cord-263699-gosqpg3k	44	54	of	of	IN
cord-263699-gosqpg3k	44	55	GDP	GDP	NNP
cord-263699-gosqpg3k	44	56	for	for	IN
cord-263699-gosqpg3k	44	57	a	a	DT
cord-263699-gosqpg3k	44	58	GTP	GTP	NNP
cord-263699-gosqpg3k	44	59	molecule	molecule	NN
cord-263699-gosqpg3k	44	60	(	(	-LRB-
cord-263699-gosqpg3k	44	61	step	step	NN
cord-263699-gosqpg3k	44	62	1	1	CD
cord-263699-gosqpg3k	44	63	)	)	-RRB-
cord-263699-gosqpg3k	44	64	.	.	.
cord-263699-gosqpg3k	45	1	This	this	DT
cord-263699-gosqpg3k	45	2	exchange	exchange	NN
cord-263699-gosqpg3k	45	3	induces	induce	VBZ
cord-263699-gosqpg3k	45	4	a	a	DT
cord-263699-gosqpg3k	45	5	conformational	conformational	JJ
cord-263699-gosqpg3k	45	6	change	change	NN
cord-263699-gosqpg3k	45	7	in	in	IN
cord-263699-gosqpg3k	45	8	Arf1	Arf1	NNP
cord-263699-gosqpg3k	45	9	that	that	WDT
cord-263699-gosqpg3k	45	10	leads	lead	VBZ
cord-263699-gosqpg3k	45	11	to	to	IN
cord-263699-gosqpg3k	45	12	the	the	DT
cord-263699-gosqpg3k	45	13	exposure	exposure	NN
cord-263699-gosqpg3k	45	14	of	of	IN
cord-263699-gosqpg3k	45	15	a	a	DT
cord-263699-gosqpg3k	45	16	myristoyl	myristoyl	JJ
cord-263699-gosqpg3k	45	17	group	group	NN
cord-263699-gosqpg3k	45	18	that	that	WDT
cord-263699-gosqpg3k	45	19	allows	allow	VBZ
cord-263699-gosqpg3k	45	20	the	the	DT
cord-263699-gosqpg3k	45	21	association	association	NN
cord-263699-gosqpg3k	45	22	of	of	IN
cord-263699-gosqpg3k	45	23	this	this	DT
cord-263699-gosqpg3k	45	24	protein	protein	NN
cord-263699-gosqpg3k	45	25	with	with	IN
cord-263699-gosqpg3k	45	26	the	the	DT
cord-263699-gosqpg3k	45	27	membrane	membrane	NN
cord-263699-gosqpg3k	45	28	[	[	-LRB-
cord-263699-gosqpg3k	45	29	31	31	CD
cord-263699-gosqpg3k	45	30	]	]	-RRB-
cord-263699-gosqpg3k	45	31	(	(	-LRB-
cord-263699-gosqpg3k	45	32	step	step	NN
cord-263699-gosqpg3k	45	33	2	2	CD
cord-263699-gosqpg3k	45	34	)	)	-RRB-
cord-263699-gosqpg3k	45	35	.	.	.
cord-263699-gosqpg3k	46	1	The	the	DT
cord-263699-gosqpg3k	46	2	membrane	membrane	NN
cord-263699-gosqpg3k	46	3	-	-	HYPH
cord-263699-gosqpg3k	46	4	bound	bind	VBN
cord-263699-gosqpg3k	46	5	Arf1-GTP	arf1-gtp	NN
cord-263699-gosqpg3k	46	6	then	then	RB
cord-263699-gosqpg3k	46	7	promotes	promote	VBZ
cord-263699-gosqpg3k	46	8	the	the	DT
cord-263699-gosqpg3k	46	9	recruitment	recruitment	NN
cord-263699-gosqpg3k	46	10	of	of	IN
cord-263699-gosqpg3k	46	11	the	the	DT
cord-263699-gosqpg3k	46	12	preformed	preformed	JJ
cord-263699-gosqpg3k	46	13	COPI	COPI	NNP
cord-263699-gosqpg3k	46	14	coat	coat	NN
cord-263699-gosqpg3k	46	15	formed	form	VBN
cord-263699-gosqpg3k	46	16	by	by	IN
cord-263699-gosqpg3k	46	17	seven	seven	CD
cord-263699-gosqpg3k	46	18	subunits	subunit	NNS
cord-263699-gosqpg3k	46	19	,	,	,
cord-263699-gosqpg3k	46	20	called	call	VBD
cord-263699-gosqpg3k	46	21	α	α	NNP
cord-263699-gosqpg3k	46	22	,	,	,
cord-263699-gosqpg3k	46	23	β	β	NNP
cord-263699-gosqpg3k	46	24	,	,	,
cord-263699-gosqpg3k	46	25	β	β	NNP
cord-263699-gosqpg3k	46	26	'	'	''
cord-263699-gosqpg3k	46	27	,	,	,
cord-263699-gosqpg3k	46	28	δ	δ	NNP
cord-263699-gosqpg3k	46	29	,	,	,
cord-263699-gosqpg3k	46	30	ε	ε	NNP
cord-263699-gosqpg3k	46	31	,	,	,
cord-263699-gosqpg3k	46	32	γ	γ	NNP
cord-263699-gosqpg3k	46	33	and	and	CC
cord-263699-gosqpg3k	46	34	ζ	ζ	NN
cord-263699-gosqpg3k	46	35	,	,	,
cord-263699-gosqpg3k	46	36	and	and	CC
cord-263699-gosqpg3k	46	37	the	the	DT
cord-263699-gosqpg3k	46	38	Arf	Arf	NNP
cord-263699-gosqpg3k	46	39	-	-	HYPH
cord-263699-gosqpg3k	46	40	GTPaseactivating	gtpaseactivate	VBG
cord-263699-gosqpg3k	46	41	protein	protein	NN
cord-263699-gosqpg3k	46	42	1	1	CD
cord-263699-gosqpg3k	46	43	(	(	-LRB-
cord-263699-gosqpg3k	46	44	ArfGAP1	arfgap1	NN
cord-263699-gosqpg3k	46	45	)	)	-RRB-
cord-263699-gosqpg3k	46	46	(	(	-LRB-
cord-263699-gosqpg3k	46	47	step	step	NN
cord-263699-gosqpg3k	46	48	3	3	CD
cord-263699-gosqpg3k	46	49	)	)	-RRB-
cord-263699-gosqpg3k	46	50	.	.	.
cord-263699-gosqpg3k	47	1	The	the	DT
cord-263699-gosqpg3k	47	2	formation	formation	NN
cord-263699-gosqpg3k	47	3	of	of	IN
cord-263699-gosqpg3k	47	4	the	the	DT
cord-263699-gosqpg3k	47	5	Arf1-GTP	arf1-gtp	NN
cord-263699-gosqpg3k	47	6	-	-	HYPH
cord-263699-gosqpg3k	47	7	COPI	COPI	NNP
cord-263699-gosqpg3k	47	8	-	-	HYPH
cord-263699-gosqpg3k	47	9	ArfGAP1	arfgap1	NN
cord-263699-gosqpg3k	47	10	complex	complex	NN
cord-263699-gosqpg3k	47	11	in	in	IN
cord-263699-gosqpg3k	47	12	the	the	DT
cord-263699-gosqpg3k	47	13	membranes	membrane	NNS
cord-263699-gosqpg3k	47	14	stimulates	stimulate	VBZ
cord-263699-gosqpg3k	47	15	the	the	DT
cord-263699-gosqpg3k	47	16	binding	binding	NN
cord-263699-gosqpg3k	47	17	and	and	CC
cord-263699-gosqpg3k	47	18	concentration	concentration	NN
cord-263699-gosqpg3k	47	19	of	of	IN
cord-263699-gosqpg3k	47	20	different	different	JJ
cord-263699-gosqpg3k	47	21	cargoes	cargo	NNS
cord-263699-gosqpg3k	47	22	(	(	-LRB-
cord-263699-gosqpg3k	47	23	step	step	NN
cord-263699-gosqpg3k	47	24	4	4	CD
cord-263699-gosqpg3k	47	25	)	)	-RRB-
cord-263699-gosqpg3k	47	26	and	and	CC
cord-263699-gosqpg3k	47	27	induces	induce	VBZ
cord-263699-gosqpg3k	47	28	the	the	DT
cord-263699-gosqpg3k	47	29	bending	bending	NN
cord-263699-gosqpg3k	47	30	of	of	IN
cord-263699-gosqpg3k	47	31	the	the	DT
cord-263699-gosqpg3k	47	32	membrane	membrane	NN
cord-263699-gosqpg3k	47	33	into	into	IN
cord-263699-gosqpg3k	47	34	a	a	DT
cord-263699-gosqpg3k	47	35	vesicle	vesicle	NN
cord-263699-gosqpg3k	47	36	(	(	-LRB-
cord-263699-gosqpg3k	47	37	step	step	NN
cord-263699-gosqpg3k	47	38	5	5	CD
cord-263699-gosqpg3k	47	39	)	)	-RRB-
cord-263699-gosqpg3k	47	40	.	.	.
cord-263699-gosqpg3k	48	1	Once	once	IN
cord-263699-gosqpg3k	48	2	the	the	DT
cord-263699-gosqpg3k	48	3	vesicle	vesicle	NN
cord-263699-gosqpg3k	48	4	is	be	VBZ
cord-263699-gosqpg3k	48	5	completed	complete	VBN
cord-263699-gosqpg3k	48	6	,	,	,
cord-263699-gosqpg3k	48	7	it	-PRON-	PRP
cord-263699-gosqpg3k	48	8	buds	bud	VBZ
cord-263699-gosqpg3k	48	9	from	from	IN
cord-263699-gosqpg3k	48	10	the	the	DT
cord-263699-gosqpg3k	48	11	membrane	membrane	NN
cord-263699-gosqpg3k	48	12	with	with	IN
cord-263699-gosqpg3k	48	13	a	a	DT
cord-263699-gosqpg3k	48	14	coat	coat	NN
cord-263699-gosqpg3k	48	15	of	of	IN
cord-263699-gosqpg3k	48	16	COPI	COPI	NNP
cord-263699-gosqpg3k	48	17	(	(	-LRB-
cord-263699-gosqpg3k	48	18	step	step	NN
cord-263699-gosqpg3k	48	19	6	6	CD
cord-263699-gosqpg3k	48	20	)	)	-RRB-
cord-263699-gosqpg3k	48	21	.	.	.
cord-263699-gosqpg3k	49	1	Finally	finally	RB
cord-263699-gosqpg3k	49	2	,	,	,
cord-263699-gosqpg3k	49	3	the	the	DT
cord-263699-gosqpg3k	49	4	coat	coat	NN
cord-263699-gosqpg3k	49	5	proteins	protein	NNS
cord-263699-gosqpg3k	49	6	are	be	VBP
cord-263699-gosqpg3k	49	7	disassembled	disassemble	VBN
cord-263699-gosqpg3k	49	8	when	when	WRB
cord-263699-gosqpg3k	49	9	the	the	DT
cord-263699-gosqpg3k	49	10	GTPase	GTPase	NNP
cord-263699-gosqpg3k	49	11	activity	activity	NN
cord-263699-gosqpg3k	49	12	of	of	IN
cord-263699-gosqpg3k	49	13	Arf1	Arf1	NNP
cord-263699-gosqpg3k	49	14	is	be	VBZ
cord-263699-gosqpg3k	49	15	enhanced	enhance	VBN
cord-263699-gosqpg3k	49	16	by	by	IN
cord-263699-gosqpg3k	49	17	ArfGAP1	arfgap1	NN
cord-263699-gosqpg3k	49	18	,	,	,
cord-263699-gosqpg3k	49	19	leading	lead	VBG
cord-263699-gosqpg3k	49	20	to	to	IN
cord-263699-gosqpg3k	49	21	the	the	DT
cord-263699-gosqpg3k	49	22	hydrolysis	hydrolysis	NN
cord-263699-gosqpg3k	49	23	of	of	IN
cord-263699-gosqpg3k	49	24	the	the	DT
cord-263699-gosqpg3k	49	25	GTP	GTP	NNP
cord-263699-gosqpg3k	49	26	molecule	molecule	NN
cord-263699-gosqpg3k	49	27	,	,	,
cord-263699-gosqpg3k	49	28	promoting	promote	VBG
cord-263699-gosqpg3k	49	29	the	the	DT
cord-263699-gosqpg3k	49	30	release	release	NN
cord-263699-gosqpg3k	49	31	of	of	IN
cord-263699-gosqpg3k	49	32	Arf1-GDP	arf1-gdp	NN
cord-263699-gosqpg3k	49	33	,	,	,
cord-263699-gosqpg3k	49	34	the	the	DT
cord-263699-gosqpg3k	49	35	COPI	COPI	NNP
cord-263699-gosqpg3k	49	36	subunits	subunit	NNS
cord-263699-gosqpg3k	49	37	,	,	,
cord-263699-gosqpg3k	49	38	and	and	CC
cord-263699-gosqpg3k	49	39	ArfGAP1	arfgap1	NN
cord-263699-gosqpg3k	49	40	from	from	IN
cord-263699-gosqpg3k	49	41	the	the	DT
cord-263699-gosqpg3k	49	42	vesicle	vesicle	NN
cord-263699-gosqpg3k	49	43	to	to	TO
cord-263699-gosqpg3k	49	44	produce	produce	VB
cord-263699-gosqpg3k	49	45	the	the	DT
cord-263699-gosqpg3k	49	46	free	free	JJ
cord-263699-gosqpg3k	49	47	carrier	carrier	NN
cord-263699-gosqpg3k	49	48	vesicle	vesicle	NN
cord-263699-gosqpg3k	49	49	used	use	VBN
cord-263699-gosqpg3k	49	50	in	in	IN
cord-263699-gosqpg3k	49	51	the	the	DT
cord-263699-gosqpg3k	49	52	vesicular	vesicular	JJ
cord-263699-gosqpg3k	49	53	transport	transport	NN
cord-263699-gosqpg3k	49	54	(	(	-LRB-
cord-263699-gosqpg3k	49	55	step	step	NN
cord-263699-gosqpg3k	49	56	7	7	CD
cord-263699-gosqpg3k	49	57	)	)	-RRB-
cord-263699-gosqpg3k	49	58	[	[	-LRB-
cord-263699-gosqpg3k	49	59	32	32	CD
cord-263699-gosqpg3k	49	60	,	,	,
cord-263699-gosqpg3k	49	61	33	33	CD
cord-263699-gosqpg3k	49	62	]	]	-RRB-
cord-263699-gosqpg3k	49	63	.	.	.
cord-263699-gosqpg3k	50	1	In	in	IN
cord-263699-gosqpg3k	50	2	addition	addition	NN
cord-263699-gosqpg3k	50	3	to	to	IN
cord-263699-gosqpg3k	50	4	Arf	Arf	NNP
cord-263699-gosqpg3k	50	5	proteins	protein	NNS
cord-263699-gosqpg3k	50	6	,	,	,
cord-263699-gosqpg3k	50	7	the	the	DT
cord-263699-gosqpg3k	50	8	participation	participation	NN
cord-263699-gosqpg3k	50	9	of	of	IN
cord-263699-gosqpg3k	50	10	specific	specific	JJ
cord-263699-gosqpg3k	50	11	Arf	Arf	NNP
cord-263699-gosqpg3k	50	12	GEFs	gefs	NN
cord-263699-gosqpg3k	50	13	has	have	VBZ
cord-263699-gosqpg3k	50	14	also	also	RB
cord-263699-gosqpg3k	50	15	been	be	VBN
cord-263699-gosqpg3k	50	16	shown	show	VBN
cord-263699-gosqpg3k	50	17	to	to	TO
cord-263699-gosqpg3k	50	18	play	play	VB
cord-263699-gosqpg3k	50	19	an	an	DT
cord-263699-gosqpg3k	50	20	essential	essential	JJ
cord-263699-gosqpg3k	50	21	role	role	NN
cord-263699-gosqpg3k	50	22	in	in	IN
cord-263699-gosqpg3k	50	23	the	the	DT
cord-263699-gosqpg3k	50	24	regulation	regulation	NN
cord-263699-gosqpg3k	50	25	of	of	IN
cord-263699-gosqpg3k	50	26	the	the	DT
cord-263699-gosqpg3k	50	27	vesicle	vesicle	NN
cord-263699-gosqpg3k	50	28	transport	transport	NN
cord-263699-gosqpg3k	50	29	.	.	.
cord-263699-gosqpg3k	51	1	For	for	IN
cord-263699-gosqpg3k	51	2	instance	instance	NN
cord-263699-gosqpg3k	51	3	,	,	,
cord-263699-gosqpg3k	51	4	the	the	DT
cord-263699-gosqpg3k	51	5	activation	activation	NN
cord-263699-gosqpg3k	51	6	of	of	IN
cord-263699-gosqpg3k	51	7	Arf1	Arf1	NNP
cord-263699-gosqpg3k	51	8	can	can	MD
cord-263699-gosqpg3k	51	9	be	be	VB
cord-263699-gosqpg3k	51	10	driven	drive	VBN
cord-263699-gosqpg3k	51	11	either	either	CC
cord-263699-gosqpg3k	51	12	by	by	IN
cord-263699-gosqpg3k	51	13	GBF1	GBF1	NNP
cord-263699-gosqpg3k	51	14	to	to	TO
cord-263699-gosqpg3k	51	15	promote	promote	VB
cord-263699-gosqpg3k	51	16	COPI	COPI	NNP
cord-263699-gosqpg3k	51	17	transport	transport	NN
cord-263699-gosqpg3k	51	18	,	,	,
cord-263699-gosqpg3k	51	19	or	or	CC
cord-263699-gosqpg3k	51	20	by	by	IN
cord-263699-gosqpg3k	51	21	the	the	DT
cord-263699-gosqpg3k	51	22	Brefeldin	Brefeldin	NNP
cord-263699-gosqpg3k	51	23	A	A	NNP
cord-263699-gosqpg3k	51	24	-	-	HYPH
cord-263699-gosqpg3k	51	25	inhibited	inhibited	JJ
cord-263699-gosqpg3k	51	26	GEFs	gefs	NN
cord-263699-gosqpg3k	51	27	1	1	CD
cord-263699-gosqpg3k	51	28	and	and	CC
cord-263699-gosqpg3k	51	29	2	2	CD
cord-263699-gosqpg3k	51	30	(	(	-LRB-
cord-263699-gosqpg3k	51	31	BIG1	BIG1	NNP
cord-263699-gosqpg3k	51	32	and	and	CC
cord-263699-gosqpg3k	51	33	BIG2	BIG2	NNP
cord-263699-gosqpg3k	51	34	)	)	-RRB-
cord-263699-gosqpg3k	51	35	to	to	TO
cord-263699-gosqpg3k	51	36	initiate	initiate	VB
cord-263699-gosqpg3k	51	37	clathrin	clathrin	NN
cord-263699-gosqpg3k	51	38	transport	transport	NN
cord-263699-gosqpg3k	51	39	;	;	:
cord-263699-gosqpg3k	51	40	thus	thus	RB
cord-263699-gosqpg3k	51	41	,	,	,
cord-263699-gosqpg3k	51	42	it	-PRON-	PRP
cord-263699-gosqpg3k	51	43	is	be	VBZ
cord-263699-gosqpg3k	51	44	thought	think	VBN
cord-263699-gosqpg3k	51	45	that	that	IN
cord-263699-gosqpg3k	51	46	Arf1	Arf1	NNP
cord-263699-gosqpg3k	51	47	is	be	VBZ
cord-263699-gosqpg3k	51	48	committed	commit	VBN
cord-263699-gosqpg3k	51	49	to	to	IN
cord-263699-gosqpg3k	51	50	each	each	DT
cord-263699-gosqpg3k	51	51	transport	transport	NN
cord-263699-gosqpg3k	51	52	pathway	pathway	NN
cord-263699-gosqpg3k	51	53	depending	depend	VBG
cord-263699-gosqpg3k	51	54	on	on	IN
cord-263699-gosqpg3k	51	55	the	the	DT
cord-263699-gosqpg3k	51	56	interaction	interaction	NN
cord-263699-gosqpg3k	51	57	with	with	IN
cord-263699-gosqpg3k	51	58	a	a	DT
cord-263699-gosqpg3k	51	59	specific	specific	JJ
cord-263699-gosqpg3k	51	60	GEF	gef	NN
cord-263699-gosqpg3k	51	61	.	.	.
cord-263699-gosqpg3k	52	1	In	in	IN
cord-263699-gosqpg3k	52	2	order	order	NN
cord-263699-gosqpg3k	52	3	to	to	TO
cord-263699-gosqpg3k	52	4	achieve	achieve	VB
cord-263699-gosqpg3k	52	5	this	this	DT
cord-263699-gosqpg3k	52	6	regulation	regulation	NN
cord-263699-gosqpg3k	52	7	,	,	,
cord-263699-gosqpg3k	52	8	the	the	DT
cord-263699-gosqpg3k	52	9	different	different	JJ
cord-263699-gosqpg3k	52	10	GEFs	gef	NNS
cord-263699-gosqpg3k	52	11	have	have	VBP
cord-263699-gosqpg3k	52	12	been	be	VBN
cord-263699-gosqpg3k	52	13	shown	show	VBN
cord-263699-gosqpg3k	52	14	to	to	TO
cord-263699-gosqpg3k	52	15	be	be	VB
cord-263699-gosqpg3k	52	16	restrained	restrain	VBN
cord-263699-gosqpg3k	52	17	to	to	IN
cord-263699-gosqpg3k	52	18	particular	particular	JJ
cord-263699-gosqpg3k	52	19	sites	site	NNS
cord-263699-gosqpg3k	52	20	where	where	WRB
cord-263699-gosqpg3k	52	21	a	a	DT
cord-263699-gosqpg3k	52	22	specific	specific	JJ
cord-263699-gosqpg3k	52	23	transport	transport	NN
cord-263699-gosqpg3k	52	24	is	be	VBZ
cord-263699-gosqpg3k	52	25	needed	need	VBN
cord-263699-gosqpg3k	52	26	;	;	:
cord-263699-gosqpg3k	52	27	for	for	IN
cord-263699-gosqpg3k	52	28	example	example	NN
cord-263699-gosqpg3k	52	29	,	,	,
cord-263699-gosqpg3k	52	30	GBF1	GBF1	NNP
cord-263699-gosqpg3k	52	31	is	be	VBZ
cord-263699-gosqpg3k	52	32	located	locate	VBN
cord-263699-gosqpg3k	52	33	at	at	IN
cord-263699-gosqpg3k	52	34	sites	site	NNS
cord-263699-gosqpg3k	52	35	where	where	WRB
cord-263699-gosqpg3k	52	36	COPI	COPI	NNP
cord-263699-gosqpg3k	52	37	exerts	exert	VBZ
cord-263699-gosqpg3k	52	38	its	-PRON-	PRP$
cord-263699-gosqpg3k	52	39	functions	function	NNS
cord-263699-gosqpg3k	52	40	,	,	,
cord-263699-gosqpg3k	52	41	either	either	CC
cord-263699-gosqpg3k	52	42	in	in	IN
cord-263699-gosqpg3k	52	43	the	the	DT
cord-263699-gosqpg3k	52	44	cis	cis	NNP
cord-263699-gosqpg3k	52	45	-	-	HYPH
cord-263699-gosqpg3k	52	46	Golgi	Golgi	NNP
cord-263699-gosqpg3k	52	47	cisternae	cisternae	NNP
cord-263699-gosqpg3k	52	48	,	,	,
cord-263699-gosqpg3k	52	49	the	the	DT
cord-263699-gosqpg3k	52	50	ERGIC	ERGIC	NNP
cord-263699-gosqpg3k	52	51	or	or	CC
cord-263699-gosqpg3k	52	52	the	the	DT
cord-263699-gosqpg3k	52	53	LDs	LDs	NNPS
cord-263699-gosqpg3k	52	54	[	[	-LRB-
cord-263699-gosqpg3k	52	55	34	34	CD
cord-263699-gosqpg3k	52	56	,	,	,
cord-263699-gosqpg3k	52	57	35	35	CD
cord-263699-gosqpg3k	52	58	]	]	-RRB-
cord-263699-gosqpg3k	52	59	,	,	,
cord-263699-gosqpg3k	52	60	whereas	whereas	IN
cord-263699-gosqpg3k	52	61	BIG1	BIG1	NNP
cord-263699-gosqpg3k	52	62	and	and	CC
cord-263699-gosqpg3k	52	63	BIG2	BIG2	NNP
cord-263699-gosqpg3k	52	64	are	be	VBP
cord-263699-gosqpg3k	52	65	located	locate	VBN
cord-263699-gosqpg3k	52	66	at	at	IN
cord-263699-gosqpg3k	52	67	the	the	DT
cord-263699-gosqpg3k	52	68	trans	trans	NNP
cord-263699-gosqpg3k	52	69	-	-	NNP
cord-263699-gosqpg3k	52	70	Golgi	Golgi	NNP
cord-263699-gosqpg3k	52	71	network	network	NN
cord-263699-gosqpg3k	52	72	(	(	-LRB-
cord-263699-gosqpg3k	52	73	TGN	TGN	NNP
cord-263699-gosqpg3k	52	74	)	)	-RRB-
cord-263699-gosqpg3k	52	75	,	,	,
cord-263699-gosqpg3k	52	76	where	where	WRB
cord-263699-gosqpg3k	52	77	clathrin	clathrin	NN
cord-263699-gosqpg3k	52	78	works	work	NNS
cord-263699-gosqpg3k	52	79	.	.	.
cord-263699-gosqpg3k	53	1	In	in	IN
cord-263699-gosqpg3k	53	2	this	this	DT
cord-263699-gosqpg3k	53	3	way	way	NN
cord-263699-gosqpg3k	53	4	,	,	,
cord-263699-gosqpg3k	53	5	each	each	DT
cord-263699-gosqpg3k	53	6	transport	transport	NN
cord-263699-gosqpg3k	53	7	pathway	pathway	NN
cord-263699-gosqpg3k	53	8	depends	depend	VBZ
cord-263699-gosqpg3k	53	9	on	on	IN
cord-263699-gosqpg3k	53	10	the	the	DT
cord-263699-gosqpg3k	53	11	precise	precise	JJ
cord-263699-gosqpg3k	53	12	temporal	temporal	JJ
cord-263699-gosqpg3k	53	13	and	and	CC
cord-263699-gosqpg3k	53	14	spatial	spatial	JJ
cord-263699-gosqpg3k	53	15	interaction	interaction	NN
cord-263699-gosqpg3k	53	16	of	of	IN
cord-263699-gosqpg3k	53	17	a	a	DT
cord-263699-gosqpg3k	53	18	specific	specific	JJ
cord-263699-gosqpg3k	53	19	GEF	gef	NN
cord-263699-gosqpg3k	53	20	with	with	IN
cord-263699-gosqpg3k	53	21	a	a	DT
cord-263699-gosqpg3k	53	22	combination	combination	NN
cord-263699-gosqpg3k	53	23	of	of	IN
cord-263699-gosqpg3k	53	24	small	small	JJ
cord-263699-gosqpg3k	53	25	GTPases	gtpase	NNS
cord-263699-gosqpg3k	53	26	.	.	.
cord-263699-gosqpg3k	54	1	GBF1	GBF1	NNP
cord-263699-gosqpg3k	54	2	is	be	VBZ
cord-263699-gosqpg3k	54	3	the	the	DT
cord-263699-gosqpg3k	54	4	GEF	GEF	NNP
cord-263699-gosqpg3k	54	5	that	that	WDT
cord-263699-gosqpg3k	54	6	specifically	specifically	RB
cord-263699-gosqpg3k	54	7	regulates	regulate	VBZ
cord-263699-gosqpg3k	54	8	the	the	DT
cord-263699-gosqpg3k	54	9	COPI	COPI	NNP
cord-263699-gosqpg3k	54	10	vesicle	vesicle	NN
cord-263699-gosqpg3k	54	11	transport	transport	NN
cord-263699-gosqpg3k	54	12	.	.	.
cord-263699-gosqpg3k	55	1	Based	base	VBN
cord-263699-gosqpg3k	55	2	on	on	IN
cord-263699-gosqpg3k	55	3	its	-PRON-	PRP$
cord-263699-gosqpg3k	55	4	size	size	NN
cord-263699-gosqpg3k	55	5	,	,	,
cord-263699-gosqpg3k	55	6	GBF1	GBF1	NNP
cord-263699-gosqpg3k	55	7	belongs	belong	VBZ
cord-263699-gosqpg3k	55	8	to	to	IN
cord-263699-gosqpg3k	55	9	the	the	DT
cord-263699-gosqpg3k	55	10	group	group	NN
cord-263699-gosqpg3k	55	11	of	of	IN
cord-263699-gosqpg3k	55	12	large	large	JJ
cord-263699-gosqpg3k	55	13	Arf	Arf	NNP
cord-263699-gosqpg3k	55	14	GEFs	gef	NNS
cord-263699-gosqpg3k	55	15	,	,	,
cord-263699-gosqpg3k	55	16	which	which	WDT
cord-263699-gosqpg3k	55	17	also	also	RB
cord-263699-gosqpg3k	55	18	contains	contain	VBZ
cord-263699-gosqpg3k	55	19	BIG1	BIG1	NNP
cord-263699-gosqpg3k	55	20	and	and	CC
cord-263699-gosqpg3k	55	21	BIG2	BIG2	NNP
cord-263699-gosqpg3k	55	22	.	.	.
cord-263699-gosqpg3k	56	1	This	this	DT
cord-263699-gosqpg3k	56	2	group	group	NN
cord-263699-gosqpg3k	56	3	of	of	IN
cord-263699-gosqpg3k	56	4	GEFs	GEFs	NNP
cord-263699-gosqpg3k	56	5	shares	share	VBZ
cord-263699-gosqpg3k	56	6	a	a	DT
cord-263699-gosqpg3k	56	7	catalytic	catalytic	JJ
cord-263699-gosqpg3k	56	8	Sec7	Sec7	NNP
cord-263699-gosqpg3k	56	9	domain	domain	NN
cord-263699-gosqpg3k	56	10	that	that	WDT
cord-263699-gosqpg3k	56	11	regulates	regulate	VBZ
cord-263699-gosqpg3k	56	12	the	the	DT
cord-263699-gosqpg3k	56	13	activation	activation	NN
cord-263699-gosqpg3k	56	14	of	of	IN
cord-263699-gosqpg3k	56	15	Arf	Arf	NNP
cord-263699-gosqpg3k	56	16	proteins	protein	NNS
cord-263699-gosqpg3k	56	17	through	through	IN
cord-263699-gosqpg3k	56	18	binding	bind	VBG
cord-263699-gosqpg3k	56	19	to	to	IN
cord-263699-gosqpg3k	56	20	the	the	DT
cord-263699-gosqpg3k	56	21	Arf	Arf	NNP
cord-263699-gosqpg3k	56	22	-	-	HYPH
cord-263699-gosqpg3k	56	23	GDP	GDP	NNP
cord-263699-gosqpg3k	56	24	form	form	NN
cord-263699-gosqpg3k	56	25	,	,	,
cord-263699-gosqpg3k	56	26	inducing	induce	VBG
cord-263699-gosqpg3k	56	27	its	-PRON-	PRP$
cord-263699-gosqpg3k	56	28	conformational	conformational	JJ
cord-263699-gosqpg3k	56	29	change	change	NN
cord-263699-gosqpg3k	56	30	,	,	,
cord-263699-gosqpg3k	56	31	and	and	CC
cord-263699-gosqpg3k	56	32	promoting	promote	VBG
cord-263699-gosqpg3k	56	33	the	the	DT
cord-263699-gosqpg3k	56	34	exchange	exchange	NN
cord-263699-gosqpg3k	56	35	of	of	IN
cord-263699-gosqpg3k	56	36	GDP	GDP	NNP
cord-263699-gosqpg3k	56	37	for	for	IN
cord-263699-gosqpg3k	56	38	GTP	GTP	NNP
cord-263699-gosqpg3k	56	39	that	that	WDT
cord-263699-gosqpg3k	56	40	leads	lead	VBZ
cord-263699-gosqpg3k	56	41	to	to	IN
cord-263699-gosqpg3k	56	42	the	the	DT
cord-263699-gosqpg3k	56	43	dissociation	dissociation	NN
cord-263699-gosqpg3k	56	44	of	of	IN
cord-263699-gosqpg3k	56	45	the	the	DT
cord-263699-gosqpg3k	56	46	protein	protein	NN
cord-263699-gosqpg3k	56	47	from	from	IN
cord-263699-gosqpg3k	56	48	GBF1	GBF1	NNP
cord-263699-gosqpg3k	56	49	[	[	-LRB-
cord-263699-gosqpg3k	56	50	36	36	CD
cord-263699-gosqpg3k	56	51	,	,	,
cord-263699-gosqpg3k	56	52	37	37	CD
cord-263699-gosqpg3k	56	53	]	]	-RRB-
cord-263699-gosqpg3k	56	54	.	.	.
cord-263699-gosqpg3k	57	1	Through	through	IN
cord-263699-gosqpg3k	57	2	this	this	DT
cord-263699-gosqpg3k	57	3	mechanism	mechanism	NN
cord-263699-gosqpg3k	57	4	,	,	,
cord-263699-gosqpg3k	57	5	GBF1	GBF1	NNP
cord-263699-gosqpg3k	57	6	can	can	MD
cord-263699-gosqpg3k	57	7	activate	activate	VB
cord-263699-gosqpg3k	57	8	Arf1	Arf1	NNP
cord-263699-gosqpg3k	57	9	,	,	,
cord-263699-gosqpg3k	57	10	Arf4	Arf4	NNP
cord-263699-gosqpg3k	57	11	,	,	,
cord-263699-gosqpg3k	57	12	and	and	CC
cord-263699-gosqpg3k	57	13	Arf5	Arf5	NNP
cord-263699-gosqpg3k	57	14	[	[	-LRB-
cord-263699-gosqpg3k	57	15	38	38	CD
cord-263699-gosqpg3k	57	16	]	]	-RRB-
cord-263699-gosqpg3k	57	17	[	[	-LRB-
cord-263699-gosqpg3k	57	18	39	39	CD
cord-263699-gosqpg3k	57	19	]	]	-RRB-
cord-263699-gosqpg3k	57	20	[	[	-LRB-
cord-263699-gosqpg3k	57	21	40	40	CD
cord-263699-gosqpg3k	57	22	]	]	-RRB-
cord-263699-gosqpg3k	57	23	.	.	.
cord-263699-gosqpg3k	58	1	In	in	IN
cord-263699-gosqpg3k	58	2	addition	addition	NN
cord-263699-gosqpg3k	58	3	to	to	IN
cord-263699-gosqpg3k	58	4	its	-PRON-	PRP$
cord-263699-gosqpg3k	58	5	Sec7	Sec7	NNP
cord-263699-gosqpg3k	58	6	domain	domain	NN
cord-263699-gosqpg3k	58	7	,	,	,
cord-263699-gosqpg3k	58	8	GBF1	GBF1	NNP
cord-263699-gosqpg3k	58	9	contains	contain	VBZ
cord-263699-gosqpg3k	58	10	five	five	CD
cord-263699-gosqpg3k	58	11	non	non	JJ
cord-263699-gosqpg3k	58	12	-	-	JJ
cord-263699-gosqpg3k	58	13	catalytic	catalytic	JJ
cord-263699-gosqpg3k	58	14	domains	domain	NNS
cord-263699-gosqpg3k	58	15	:	:	:
cord-263699-gosqpg3k	58	16	Figure	figure	NN
cord-263699-gosqpg3k	58	17	2	2	CD
cord-263699-gosqpg3k	58	18	.	.	.
cord-263699-gosqpg3k	59	1	Mechanism	mechanism	NN
cord-263699-gosqpg3k	59	2	of	of	IN
cord-263699-gosqpg3k	59	3	COPI	COPI	NNP
cord-263699-gosqpg3k	59	4	transport	transport	NN
cord-263699-gosqpg3k	59	5	.	.	.
cord-263699-gosqpg3k	60	1	COPI	COPI	NNP
cord-263699-gosqpg3k	60	2	vesicle	vesicle	NN
cord-263699-gosqpg3k	60	3	formation	formation	NN
cord-263699-gosqpg3k	60	4	starts	start	VBZ
cord-263699-gosqpg3k	60	5	when	when	WRB
cord-263699-gosqpg3k	60	6	the	the	DT
cord-263699-gosqpg3k	60	7	small	small	JJ
cord-263699-gosqpg3k	60	8	GTPase	GTPase	NNP
cord-263699-gosqpg3k	60	9	Arf1	Arf1	NNP
cord-263699-gosqpg3k	60	10	,	,	,
cord-263699-gosqpg3k	60	11	bound	bind	VBN
cord-263699-gosqpg3k	60	12	to	to	IN
cord-263699-gosqpg3k	60	13	GDP	GDP	NNP
cord-263699-gosqpg3k	60	14	(	(	-LRB-
cord-263699-gosqpg3k	60	15	Arf1-GDP	Arf1-GDP	NNP
cord-263699-gosqpg3k	60	16	)	)	-RRB-
cord-263699-gosqpg3k	60	17	,	,	,
cord-263699-gosqpg3k	60	18	associates	associate	NNS
cord-263699-gosqpg3k	60	19	with	with	IN
cord-263699-gosqpg3k	60	20	the	the	DT
cord-263699-gosqpg3k	60	21	Golgi	Golgi	NNP
cord-263699-gosqpg3k	60	22	-	-	HYPH
cord-263699-gosqpg3k	60	23	specific	specific	JJ
cord-263699-gosqpg3k	60	24	Brefeldin	Brefeldin	NNP
cord-263699-gosqpg3k	60	25	A	A	NNP
cord-263699-gosqpg3k	60	26	(	(	-LRB-
cord-263699-gosqpg3k	60	27	BFA	BFA	NNP
cord-263699-gosqpg3k	60	28	)	)	-RRB-
cord-263699-gosqpg3k	60	29	resistance	resistance	NN
cord-263699-gosqpg3k	60	30	factor	factor	NN
cord-263699-gosqpg3k	60	31	1	1	CD
cord-263699-gosqpg3k	60	32	(	(	-LRB-
cord-263699-gosqpg3k	60	33	GBF1	GBF1	NNP
cord-263699-gosqpg3k	60	34	)	)	-RRB-
cord-263699-gosqpg3k	60	35	,	,	,
cord-263699-gosqpg3k	60	36	a	a	DT
cord-263699-gosqpg3k	60	37	guanine	guanine	NN
cord-263699-gosqpg3k	60	38	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	60	39	exchange	exchange	NN
cord-263699-gosqpg3k	60	40	factor	factor	NN
cord-263699-gosqpg3k	60	41	(	(	-LRB-
cord-263699-gosqpg3k	60	42	GEF	GEF	NNP
cord-263699-gosqpg3k	60	43	)	)	-RRB-
cord-263699-gosqpg3k	60	44	that	that	WDT
cord-263699-gosqpg3k	60	45	catalyzes	catalyze	VBZ
cord-263699-gosqpg3k	60	46	the	the	DT
cord-263699-gosqpg3k	60	47	activation	activation	NN
cord-263699-gosqpg3k	60	48	of	of	IN
cord-263699-gosqpg3k	60	49	Arf1	Arf1	NNP
cord-263699-gosqpg3k	60	50	by	by	IN
cord-263699-gosqpg3k	60	51	promoting	promote	VBG
cord-263699-gosqpg3k	60	52	the	the	DT
cord-263699-gosqpg3k	60	53	exchange	exchange	NN
cord-263699-gosqpg3k	60	54	of	of	IN
cord-263699-gosqpg3k	60	55	GDP	GDP	NNP
cord-263699-gosqpg3k	60	56	for	for	IN
cord-263699-gosqpg3k	60	57	a	a	DT
cord-263699-gosqpg3k	60	58	GTP	GTP	NNP
cord-263699-gosqpg3k	60	59	molecule	molecule	NN
cord-263699-gosqpg3k	60	60	(	(	-LRB-
cord-263699-gosqpg3k	60	61	step	step	NN
cord-263699-gosqpg3k	60	62	1	1	CD
cord-263699-gosqpg3k	60	63	)	)	-RRB-
cord-263699-gosqpg3k	60	64	.	.	.
cord-263699-gosqpg3k	61	1	This	this	DT
cord-263699-gosqpg3k	61	2	exchange	exchange	NN
cord-263699-gosqpg3k	61	3	induces	induce	VBZ
cord-263699-gosqpg3k	61	4	a	a	DT
cord-263699-gosqpg3k	61	5	conformational	conformational	JJ
cord-263699-gosqpg3k	61	6	change	change	NN
cord-263699-gosqpg3k	61	7	in	in	IN
cord-263699-gosqpg3k	61	8	Arf1	Arf1	NNP
cord-263699-gosqpg3k	61	9	that	that	WDT
cord-263699-gosqpg3k	61	10	leads	lead	VBZ
cord-263699-gosqpg3k	61	11	to	to	IN
cord-263699-gosqpg3k	61	12	the	the	DT
cord-263699-gosqpg3k	61	13	exposure	exposure	NN
cord-263699-gosqpg3k	61	14	of	of	IN
cord-263699-gosqpg3k	61	15	a	a	DT
cord-263699-gosqpg3k	61	16	myristoyl	myristoyl	JJ
cord-263699-gosqpg3k	61	17	group	group	NN
cord-263699-gosqpg3k	61	18	that	that	WDT
cord-263699-gosqpg3k	61	19	allows	allow	VBZ
cord-263699-gosqpg3k	61	20	the	the	DT
cord-263699-gosqpg3k	61	21	association	association	NN
cord-263699-gosqpg3k	61	22	of	of	IN
cord-263699-gosqpg3k	61	23	this	this	DT
cord-263699-gosqpg3k	61	24	protein	protein	NN
cord-263699-gosqpg3k	61	25	with	with	IN
cord-263699-gosqpg3k	61	26	the	the	DT
cord-263699-gosqpg3k	61	27	membrane	membrane	NN
cord-263699-gosqpg3k	61	28	[	[	-LRB-
cord-263699-gosqpg3k	61	29	31	31	CD
cord-263699-gosqpg3k	61	30	]	]	-RRB-
cord-263699-gosqpg3k	61	31	(	(	-LRB-
cord-263699-gosqpg3k	61	32	step	step	NN
cord-263699-gosqpg3k	61	33	2	2	CD
cord-263699-gosqpg3k	61	34	)	)	-RRB-
cord-263699-gosqpg3k	61	35	.	.	.
cord-263699-gosqpg3k	62	1	The	the	DT
cord-263699-gosqpg3k	62	2	membrane	membrane	NN
cord-263699-gosqpg3k	62	3	-	-	HYPH
cord-263699-gosqpg3k	62	4	bound	bind	VBN
cord-263699-gosqpg3k	62	5	Arf1-GTP	arf1-gtp	NN
cord-263699-gosqpg3k	62	6	then	then	RB
cord-263699-gosqpg3k	62	7	promotes	promote	VBZ
cord-263699-gosqpg3k	62	8	the	the	DT
cord-263699-gosqpg3k	62	9	recruitment	recruitment	NN
cord-263699-gosqpg3k	62	10	of	of	IN
cord-263699-gosqpg3k	62	11	the	the	DT
cord-263699-gosqpg3k	62	12	preformed	preformed	JJ
cord-263699-gosqpg3k	62	13	COPI	COPI	NNP
cord-263699-gosqpg3k	62	14	coat	coat	NN
cord-263699-gosqpg3k	62	15	formed	form	VBN
cord-263699-gosqpg3k	62	16	by	by	IN
cord-263699-gosqpg3k	62	17	seven	seven	CD
cord-263699-gosqpg3k	62	18	subunits	subunit	NNS
cord-263699-gosqpg3k	62	19	,	,	,
cord-263699-gosqpg3k	62	20	called	call	VBD
cord-263699-gosqpg3k	62	21	α	α	NNP
cord-263699-gosqpg3k	62	22	,	,	,
cord-263699-gosqpg3k	62	23	β	β	NNP
cord-263699-gosqpg3k	62	24	,	,	,
cord-263699-gosqpg3k	62	25	β	β	NNP
cord-263699-gosqpg3k	62	26	'	'	''
cord-263699-gosqpg3k	62	27	,	,	,
cord-263699-gosqpg3k	62	28	δ	δ	NNP
cord-263699-gosqpg3k	62	29	,	,	,
cord-263699-gosqpg3k	62	30	ε	ε	NNP
cord-263699-gosqpg3k	62	31	,	,	,
cord-263699-gosqpg3k	62	32	γ	γ	NNP
cord-263699-gosqpg3k	62	33	and	and	CC
cord-263699-gosqpg3k	62	34	ζ	ζ	NN
cord-263699-gosqpg3k	62	35	,	,	,
cord-263699-gosqpg3k	62	36	and	and	CC
cord-263699-gosqpg3k	62	37	the	the	DT
cord-263699-gosqpg3k	62	38	Arf	Arf	NNP
cord-263699-gosqpg3k	62	39	-	-	HYPH
cord-263699-gosqpg3k	62	40	GTPase	GTPase	NNP
cord-263699-gosqpg3k	62	41	-	-	HYPH
cord-263699-gosqpg3k	62	42	activating	activate	VBG
cord-263699-gosqpg3k	62	43	protein	protein	NN
cord-263699-gosqpg3k	62	44	1	1	CD
cord-263699-gosqpg3k	62	45	(	(	-LRB-
cord-263699-gosqpg3k	62	46	ArfGAP1	arfgap1	NN
cord-263699-gosqpg3k	62	47	)	)	-RRB-
cord-263699-gosqpg3k	62	48	(	(	-LRB-
cord-263699-gosqpg3k	62	49	step	step	NN
cord-263699-gosqpg3k	62	50	3	3	CD
cord-263699-gosqpg3k	62	51	)	)	-RRB-
cord-263699-gosqpg3k	62	52	.	.	.
cord-263699-gosqpg3k	63	1	The	the	DT
cord-263699-gosqpg3k	63	2	formation	formation	NN
cord-263699-gosqpg3k	63	3	of	of	IN
cord-263699-gosqpg3k	63	4	the	the	DT
cord-263699-gosqpg3k	63	5	Arf1-GTP	arf1-gtp	NN
cord-263699-gosqpg3k	63	6	-	-	HYPH
cord-263699-gosqpg3k	63	7	COPI	COPI	NNP
cord-263699-gosqpg3k	63	8	-	-	HYPH
cord-263699-gosqpg3k	63	9	ArfGAP1	arfgap1	NN
cord-263699-gosqpg3k	63	10	complex	complex	NN
cord-263699-gosqpg3k	63	11	in	in	IN
cord-263699-gosqpg3k	63	12	the	the	DT
cord-263699-gosqpg3k	63	13	membranes	membrane	NNS
cord-263699-gosqpg3k	63	14	stimulates	stimulate	VBZ
cord-263699-gosqpg3k	63	15	the	the	DT
cord-263699-gosqpg3k	63	16	binding	binding	NN
cord-263699-gosqpg3k	63	17	and	and	CC
cord-263699-gosqpg3k	63	18	concentration	concentration	NN
cord-263699-gosqpg3k	63	19	of	of	IN
cord-263699-gosqpg3k	63	20	different	different	JJ
cord-263699-gosqpg3k	63	21	cargoes	cargo	NNS
cord-263699-gosqpg3k	63	22	(	(	-LRB-
cord-263699-gosqpg3k	63	23	step	step	NN
cord-263699-gosqpg3k	63	24	4	4	CD
cord-263699-gosqpg3k	63	25	)	)	-RRB-
cord-263699-gosqpg3k	63	26	and	and	CC
cord-263699-gosqpg3k	63	27	induces	induce	VBZ
cord-263699-gosqpg3k	63	28	the	the	DT
cord-263699-gosqpg3k	63	29	bending	bending	NN
cord-263699-gosqpg3k	63	30	of	of	IN
cord-263699-gosqpg3k	63	31	the	the	DT
cord-263699-gosqpg3k	63	32	membrane	membrane	NN
cord-263699-gosqpg3k	63	33	into	into	IN
cord-263699-gosqpg3k	63	34	a	a	DT
cord-263699-gosqpg3k	63	35	vesicle	vesicle	NN
cord-263699-gosqpg3k	63	36	(	(	-LRB-
cord-263699-gosqpg3k	63	37	step	step	NN
cord-263699-gosqpg3k	63	38	5	5	CD
cord-263699-gosqpg3k	63	39	)	)	-RRB-
cord-263699-gosqpg3k	63	40	.	.	.
cord-263699-gosqpg3k	64	1	Once	once	IN
cord-263699-gosqpg3k	64	2	the	the	DT
cord-263699-gosqpg3k	64	3	vesicle	vesicle	NN
cord-263699-gosqpg3k	64	4	is	be	VBZ
cord-263699-gosqpg3k	64	5	completed	complete	VBN
cord-263699-gosqpg3k	64	6	,	,	,
cord-263699-gosqpg3k	64	7	it	-PRON-	PRP
cord-263699-gosqpg3k	64	8	buds	bud	VBZ
cord-263699-gosqpg3k	64	9	from	from	IN
cord-263699-gosqpg3k	64	10	the	the	DT
cord-263699-gosqpg3k	64	11	membrane	membrane	NN
cord-263699-gosqpg3k	64	12	with	with	IN
cord-263699-gosqpg3k	64	13	a	a	DT
cord-263699-gosqpg3k	64	14	coat	coat	NN
cord-263699-gosqpg3k	64	15	of	of	IN
cord-263699-gosqpg3k	64	16	COPI	COPI	NNP
cord-263699-gosqpg3k	64	17	(	(	-LRB-
cord-263699-gosqpg3k	64	18	step	step	NN
cord-263699-gosqpg3k	64	19	6	6	CD
cord-263699-gosqpg3k	64	20	)	)	-RRB-
cord-263699-gosqpg3k	64	21	.	.	.
cord-263699-gosqpg3k	65	1	Finally	finally	RB
cord-263699-gosqpg3k	65	2	,	,	,
cord-263699-gosqpg3k	65	3	the	the	DT
cord-263699-gosqpg3k	65	4	coat	coat	NN
cord-263699-gosqpg3k	65	5	proteins	protein	NNS
cord-263699-gosqpg3k	65	6	are	be	VBP
cord-263699-gosqpg3k	65	7	disassembled	disassemble	VBN
cord-263699-gosqpg3k	65	8	when	when	WRB
cord-263699-gosqpg3k	65	9	the	the	DT
cord-263699-gosqpg3k	65	10	GTPase	GTPase	NNP
cord-263699-gosqpg3k	65	11	activity	activity	NN
cord-263699-gosqpg3k	65	12	of	of	IN
cord-263699-gosqpg3k	65	13	Arf1	Arf1	NNP
cord-263699-gosqpg3k	65	14	is	be	VBZ
cord-263699-gosqpg3k	65	15	enhanced	enhance	VBN
cord-263699-gosqpg3k	65	16	by	by	IN
cord-263699-gosqpg3k	65	17	ArfGAP1	arfgap1	NN
cord-263699-gosqpg3k	65	18	,	,	,
cord-263699-gosqpg3k	65	19	leading	lead	VBG
cord-263699-gosqpg3k	65	20	to	to	IN
cord-263699-gosqpg3k	65	21	the	the	DT
cord-263699-gosqpg3k	65	22	hydrolysis	hydrolysis	NN
cord-263699-gosqpg3k	65	23	of	of	IN
cord-263699-gosqpg3k	65	24	the	the	DT
cord-263699-gosqpg3k	65	25	GTP	GTP	NNP
cord-263699-gosqpg3k	65	26	molecule	molecule	NN
cord-263699-gosqpg3k	65	27	,	,	,
cord-263699-gosqpg3k	65	28	promoting	promote	VBG
cord-263699-gosqpg3k	65	29	the	the	DT
cord-263699-gosqpg3k	65	30	release	release	NN
cord-263699-gosqpg3k	65	31	of	of	IN
cord-263699-gosqpg3k	65	32	Arf1-GDP	arf1-gdp	NN
cord-263699-gosqpg3k	65	33	,	,	,
cord-263699-gosqpg3k	65	34	the	the	DT
cord-263699-gosqpg3k	65	35	COPI	COPI	NNP
cord-263699-gosqpg3k	65	36	subunits	subunit	NNS
cord-263699-gosqpg3k	65	37	,	,	,
cord-263699-gosqpg3k	65	38	and	and	CC
cord-263699-gosqpg3k	65	39	ArfGAP1	arfgap1	NN
cord-263699-gosqpg3k	65	40	from	from	IN
cord-263699-gosqpg3k	65	41	the	the	DT
cord-263699-gosqpg3k	65	42	vesicle	vesicle	NN
cord-263699-gosqpg3k	65	43	to	to	TO
cord-263699-gosqpg3k	65	44	produce	produce	VB
cord-263699-gosqpg3k	65	45	the	the	DT
cord-263699-gosqpg3k	65	46	free	free	JJ
cord-263699-gosqpg3k	65	47	carrier	carrier	NN
cord-263699-gosqpg3k	65	48	vesicle	vesicle	NN
cord-263699-gosqpg3k	65	49	used	use	VBN
cord-263699-gosqpg3k	65	50	in	in	IN
cord-263699-gosqpg3k	65	51	the	the	DT
cord-263699-gosqpg3k	65	52	vesicular	vesicular	JJ
cord-263699-gosqpg3k	65	53	transport	transport	NN
cord-263699-gosqpg3k	65	54	(	(	-LRB-
cord-263699-gosqpg3k	65	55	step	step	NN
cord-263699-gosqpg3k	65	56	7	7	CD
cord-263699-gosqpg3k	65	57	)	)	-RRB-
cord-263699-gosqpg3k	65	58	[	[	-LRB-
cord-263699-gosqpg3k	65	59	32	32	CD
cord-263699-gosqpg3k	65	60	,	,	,
cord-263699-gosqpg3k	65	61	33	33	CD
cord-263699-gosqpg3k	65	62	]	]	-RRB-
cord-263699-gosqpg3k	65	63	.	.	.
cord-263699-gosqpg3k	66	1	In	in	IN
cord-263699-gosqpg3k	66	2	addition	addition	NN
cord-263699-gosqpg3k	66	3	to	to	IN
cord-263699-gosqpg3k	66	4	Arf	Arf	NNP
cord-263699-gosqpg3k	66	5	proteins	protein	NNS
cord-263699-gosqpg3k	66	6	,	,	,
cord-263699-gosqpg3k	66	7	the	the	DT
cord-263699-gosqpg3k	66	8	participation	participation	NN
cord-263699-gosqpg3k	66	9	of	of	IN
cord-263699-gosqpg3k	66	10	specific	specific	JJ
cord-263699-gosqpg3k	66	11	Arf	Arf	NNP
cord-263699-gosqpg3k	66	12	GEFs	gefs	NN
cord-263699-gosqpg3k	66	13	has	have	VBZ
cord-263699-gosqpg3k	66	14	also	also	RB
cord-263699-gosqpg3k	66	15	been	be	VBN
cord-263699-gosqpg3k	66	16	shown	show	VBN
cord-263699-gosqpg3k	66	17	to	to	TO
cord-263699-gosqpg3k	66	18	play	play	VB
cord-263699-gosqpg3k	66	19	an	an	DT
cord-263699-gosqpg3k	66	20	essential	essential	JJ
cord-263699-gosqpg3k	66	21	role	role	NN
cord-263699-gosqpg3k	66	22	in	in	IN
cord-263699-gosqpg3k	66	23	the	the	DT
cord-263699-gosqpg3k	66	24	regulation	regulation	NN
cord-263699-gosqpg3k	66	25	of	of	IN
cord-263699-gosqpg3k	66	26	the	the	DT
cord-263699-gosqpg3k	66	27	vesicle	vesicle	NN
cord-263699-gosqpg3k	66	28	transport	transport	NN
cord-263699-gosqpg3k	66	29	.	.	.
cord-263699-gosqpg3k	67	1	For	for	IN
cord-263699-gosqpg3k	67	2	instance	instance	NN
cord-263699-gosqpg3k	67	3	,	,	,
cord-263699-gosqpg3k	67	4	the	the	DT
cord-263699-gosqpg3k	67	5	activation	activation	NN
cord-263699-gosqpg3k	67	6	of	of	IN
cord-263699-gosqpg3k	67	7	Arf1	Arf1	NNP
cord-263699-gosqpg3k	67	8	can	can	MD
cord-263699-gosqpg3k	67	9	be	be	VB
cord-263699-gosqpg3k	67	10	driven	drive	VBN
cord-263699-gosqpg3k	67	11	either	either	CC
cord-263699-gosqpg3k	67	12	by	by	IN
cord-263699-gosqpg3k	67	13	GBF1	GBF1	NNP
cord-263699-gosqpg3k	67	14	to	to	TO
cord-263699-gosqpg3k	67	15	promote	promote	VB
cord-263699-gosqpg3k	67	16	COPI	COPI	NNP
cord-263699-gosqpg3k	67	17	transport	transport	NN
cord-263699-gosqpg3k	67	18	,	,	,
cord-263699-gosqpg3k	67	19	or	or	CC
cord-263699-gosqpg3k	67	20	by	by	IN
cord-263699-gosqpg3k	67	21	the	the	DT
cord-263699-gosqpg3k	67	22	Brefeldin	Brefeldin	NNP
cord-263699-gosqpg3k	67	23	A	A	NNP
cord-263699-gosqpg3k	67	24	-	-	HYPH
cord-263699-gosqpg3k	67	25	inhibited	inhibited	JJ
cord-263699-gosqpg3k	67	26	GEFs	gefs	NN
cord-263699-gosqpg3k	67	27	1	1	CD
cord-263699-gosqpg3k	67	28	and	and	CC
cord-263699-gosqpg3k	67	29	2	2	CD
cord-263699-gosqpg3k	67	30	(	(	-LRB-
cord-263699-gosqpg3k	67	31	BIG1	BIG1	NNP
cord-263699-gosqpg3k	67	32	and	and	CC
cord-263699-gosqpg3k	67	33	BIG2	BIG2	NNP
cord-263699-gosqpg3k	67	34	)	)	-RRB-
cord-263699-gosqpg3k	67	35	to	to	TO
cord-263699-gosqpg3k	67	36	initiate	initiate	VB
cord-263699-gosqpg3k	67	37	clathrin	clathrin	NN
cord-263699-gosqpg3k	67	38	transport	transport	NN
cord-263699-gosqpg3k	67	39	;	;	:
cord-263699-gosqpg3k	67	40	thus	thus	RB
cord-263699-gosqpg3k	67	41	,	,	,
cord-263699-gosqpg3k	67	42	it	-PRON-	PRP
cord-263699-gosqpg3k	67	43	is	be	VBZ
cord-263699-gosqpg3k	67	44	thought	think	VBN
cord-263699-gosqpg3k	67	45	that	that	IN
cord-263699-gosqpg3k	67	46	Arf1	Arf1	NNP
cord-263699-gosqpg3k	67	47	is	be	VBZ
cord-263699-gosqpg3k	67	48	committed	commit	VBN
cord-263699-gosqpg3k	67	49	to	to	IN
cord-263699-gosqpg3k	67	50	each	each	DT
cord-263699-gosqpg3k	67	51	transport	transport	NN
cord-263699-gosqpg3k	67	52	pathway	pathway	NN
cord-263699-gosqpg3k	67	53	depending	depend	VBG
cord-263699-gosqpg3k	67	54	on	on	IN
cord-263699-gosqpg3k	67	55	the	the	DT
cord-263699-gosqpg3k	67	56	interaction	interaction	NN
cord-263699-gosqpg3k	67	57	with	with	IN
cord-263699-gosqpg3k	67	58	a	a	DT
cord-263699-gosqpg3k	67	59	specific	specific	JJ
cord-263699-gosqpg3k	67	60	GEF	gef	NN
cord-263699-gosqpg3k	67	61	.	.	.
cord-263699-gosqpg3k	68	1	In	in	IN
cord-263699-gosqpg3k	68	2	order	order	NN
cord-263699-gosqpg3k	68	3	to	to	TO
cord-263699-gosqpg3k	68	4	achieve	achieve	VB
cord-263699-gosqpg3k	68	5	this	this	DT
cord-263699-gosqpg3k	68	6	regulation	regulation	NN
cord-263699-gosqpg3k	68	7	,	,	,
cord-263699-gosqpg3k	68	8	the	the	DT
cord-263699-gosqpg3k	68	9	different	different	JJ
cord-263699-gosqpg3k	68	10	GEFs	gef	NNS
cord-263699-gosqpg3k	68	11	have	have	VBP
cord-263699-gosqpg3k	68	12	been	be	VBN
cord-263699-gosqpg3k	68	13	shown	show	VBN
cord-263699-gosqpg3k	68	14	to	to	TO
cord-263699-gosqpg3k	68	15	be	be	VB
cord-263699-gosqpg3k	68	16	restrained	restrain	VBN
cord-263699-gosqpg3k	68	17	to	to	IN
cord-263699-gosqpg3k	68	18	particular	particular	JJ
cord-263699-gosqpg3k	68	19	sites	site	NNS
cord-263699-gosqpg3k	68	20	where	where	WRB
cord-263699-gosqpg3k	68	21	a	a	DT
cord-263699-gosqpg3k	68	22	specific	specific	JJ
cord-263699-gosqpg3k	68	23	transport	transport	NN
cord-263699-gosqpg3k	68	24	is	be	VBZ
cord-263699-gosqpg3k	68	25	needed	need	VBN
cord-263699-gosqpg3k	68	26	;	;	:
cord-263699-gosqpg3k	68	27	for	for	IN
cord-263699-gosqpg3k	68	28	example	example	NN
cord-263699-gosqpg3k	68	29	,	,	,
cord-263699-gosqpg3k	68	30	GBF1	GBF1	NNP
cord-263699-gosqpg3k	68	31	is	be	VBZ
cord-263699-gosqpg3k	68	32	located	locate	VBN
cord-263699-gosqpg3k	68	33	at	at	IN
cord-263699-gosqpg3k	68	34	sites	site	NNS
cord-263699-gosqpg3k	68	35	where	where	WRB
cord-263699-gosqpg3k	68	36	COPI	COPI	NNP
cord-263699-gosqpg3k	68	37	exerts	exert	VBZ
cord-263699-gosqpg3k	68	38	its	-PRON-	PRP$
cord-263699-gosqpg3k	68	39	functions	function	NNS
cord-263699-gosqpg3k	68	40	,	,	,
cord-263699-gosqpg3k	68	41	either	either	CC
cord-263699-gosqpg3k	68	42	in	in	IN
cord-263699-gosqpg3k	68	43	the	the	DT
cord-263699-gosqpg3k	68	44	cis	cis	NNP
cord-263699-gosqpg3k	68	45	-	-	HYPH
cord-263699-gosqpg3k	68	46	Golgi	Golgi	NNP
cord-263699-gosqpg3k	68	47	cisternae	cisternae	NNP
cord-263699-gosqpg3k	68	48	,	,	,
cord-263699-gosqpg3k	68	49	the	the	DT
cord-263699-gosqpg3k	68	50	ERGIC	ERGIC	NNP
cord-263699-gosqpg3k	68	51	or	or	CC
cord-263699-gosqpg3k	68	52	the	the	DT
cord-263699-gosqpg3k	68	53	LDs	LDs	NNPS
cord-263699-gosqpg3k	68	54	[	[	-LRB-
cord-263699-gosqpg3k	68	55	34	34	CD
cord-263699-gosqpg3k	68	56	,	,	,
cord-263699-gosqpg3k	68	57	35	35	CD
cord-263699-gosqpg3k	68	58	]	]	-RRB-
cord-263699-gosqpg3k	68	59	,	,	,
cord-263699-gosqpg3k	68	60	whereas	whereas	IN
cord-263699-gosqpg3k	68	61	BIG1	BIG1	NNP
cord-263699-gosqpg3k	68	62	and	and	CC
cord-263699-gosqpg3k	68	63	BIG2	BIG2	NNP
cord-263699-gosqpg3k	68	64	are	be	VBP
cord-263699-gosqpg3k	68	65	located	locate	VBN
cord-263699-gosqpg3k	68	66	at	at	IN
cord-263699-gosqpg3k	68	67	the	the	DT
cord-263699-gosqpg3k	68	68	trans	trans	NNP
cord-263699-gosqpg3k	68	69	-	-	NNP
cord-263699-gosqpg3k	68	70	Golgi	Golgi	NNP
cord-263699-gosqpg3k	68	71	network	network	NN
cord-263699-gosqpg3k	68	72	(	(	-LRB-
cord-263699-gosqpg3k	68	73	TGN	TGN	NNP
cord-263699-gosqpg3k	68	74	)	)	-RRB-
cord-263699-gosqpg3k	68	75	,	,	,
cord-263699-gosqpg3k	68	76	where	where	WRB
cord-263699-gosqpg3k	68	77	clathrin	clathrin	NN
cord-263699-gosqpg3k	68	78	works	work	NNS
cord-263699-gosqpg3k	68	79	.	.	.
cord-263699-gosqpg3k	69	1	In	in	IN
cord-263699-gosqpg3k	69	2	this	this	DT
cord-263699-gosqpg3k	69	3	way	way	NN
cord-263699-gosqpg3k	69	4	,	,	,
cord-263699-gosqpg3k	69	5	each	each	DT
cord-263699-gosqpg3k	69	6	transport	transport	NN
cord-263699-gosqpg3k	69	7	pathway	pathway	NN
cord-263699-gosqpg3k	69	8	depends	depend	VBZ
cord-263699-gosqpg3k	69	9	on	on	IN
cord-263699-gosqpg3k	69	10	the	the	DT
cord-263699-gosqpg3k	69	11	precise	precise	JJ
cord-263699-gosqpg3k	69	12	temporal	temporal	JJ
cord-263699-gosqpg3k	69	13	and	and	CC
cord-263699-gosqpg3k	69	14	spatial	spatial	JJ
cord-263699-gosqpg3k	69	15	interaction	interaction	NN
cord-263699-gosqpg3k	69	16	of	of	IN
cord-263699-gosqpg3k	69	17	a	a	DT
cord-263699-gosqpg3k	69	18	specific	specific	JJ
cord-263699-gosqpg3k	69	19	GEF	gef	NN
cord-263699-gosqpg3k	69	20	with	with	IN
cord-263699-gosqpg3k	69	21	a	a	DT
cord-263699-gosqpg3k	69	22	combination	combination	NN
cord-263699-gosqpg3k	69	23	of	of	IN
cord-263699-gosqpg3k	69	24	small	small	JJ
cord-263699-gosqpg3k	69	25	GTPases	gtpase	NNS
cord-263699-gosqpg3k	69	26	.	.	.
cord-263699-gosqpg3k	70	1	GBF1	GBF1	NNP
cord-263699-gosqpg3k	70	2	is	be	VBZ
cord-263699-gosqpg3k	70	3	the	the	DT
cord-263699-gosqpg3k	70	4	GEF	GEF	NNP
cord-263699-gosqpg3k	70	5	that	that	WDT
cord-263699-gosqpg3k	70	6	specifically	specifically	RB
cord-263699-gosqpg3k	70	7	regulates	regulate	VBZ
cord-263699-gosqpg3k	70	8	the	the	DT
cord-263699-gosqpg3k	70	9	COPI	COPI	NNP
cord-263699-gosqpg3k	70	10	vesicle	vesicle	NN
cord-263699-gosqpg3k	70	11	transport	transport	NN
cord-263699-gosqpg3k	70	12	.	.	.
cord-263699-gosqpg3k	71	1	Based	base	VBN
cord-263699-gosqpg3k	71	2	on	on	IN
cord-263699-gosqpg3k	71	3	its	-PRON-	PRP$
cord-263699-gosqpg3k	71	4	size	size	NN
cord-263699-gosqpg3k	71	5	,	,	,
cord-263699-gosqpg3k	71	6	GBF1	GBF1	NNP
cord-263699-gosqpg3k	71	7	belongs	belong	VBZ
cord-263699-gosqpg3k	71	8	to	to	IN
cord-263699-gosqpg3k	71	9	the	the	DT
cord-263699-gosqpg3k	71	10	group	group	NN
cord-263699-gosqpg3k	71	11	of	of	IN
cord-263699-gosqpg3k	71	12	large	large	JJ
cord-263699-gosqpg3k	71	13	Arf	Arf	NNP
cord-263699-gosqpg3k	71	14	GEFs	gef	NNS
cord-263699-gosqpg3k	71	15	,	,	,
cord-263699-gosqpg3k	71	16	which	which	WDT
cord-263699-gosqpg3k	71	17	also	also	RB
cord-263699-gosqpg3k	71	18	contains	contain	VBZ
cord-263699-gosqpg3k	71	19	BIG1	BIG1	NNP
cord-263699-gosqpg3k	71	20	and	and	CC
cord-263699-gosqpg3k	71	21	BIG2	BIG2	NNP
cord-263699-gosqpg3k	71	22	.	.	.
cord-263699-gosqpg3k	72	1	This	this	DT
cord-263699-gosqpg3k	72	2	group	group	NN
cord-263699-gosqpg3k	72	3	of	of	IN
cord-263699-gosqpg3k	72	4	GEFs	GEFs	NNP
cord-263699-gosqpg3k	72	5	shares	share	VBZ
cord-263699-gosqpg3k	72	6	a	a	DT
cord-263699-gosqpg3k	72	7	catalytic	catalytic	JJ
cord-263699-gosqpg3k	72	8	Sec7	Sec7	NNP
cord-263699-gosqpg3k	72	9	domain	domain	NN
cord-263699-gosqpg3k	72	10	that	that	WDT
cord-263699-gosqpg3k	72	11	regulates	regulate	VBZ
cord-263699-gosqpg3k	72	12	the	the	DT
cord-263699-gosqpg3k	72	13	activation	activation	NN
cord-263699-gosqpg3k	72	14	of	of	IN
cord-263699-gosqpg3k	72	15	Arf	Arf	NNP
cord-263699-gosqpg3k	72	16	proteins	protein	NNS
cord-263699-gosqpg3k	72	17	through	through	IN
cord-263699-gosqpg3k	72	18	binding	bind	VBG
cord-263699-gosqpg3k	72	19	to	to	IN
cord-263699-gosqpg3k	72	20	the	the	DT
cord-263699-gosqpg3k	72	21	Arf	Arf	NNP
cord-263699-gosqpg3k	72	22	-	-	HYPH
cord-263699-gosqpg3k	72	23	GDP	GDP	NNP
cord-263699-gosqpg3k	72	24	form	form	NN
cord-263699-gosqpg3k	72	25	,	,	,
cord-263699-gosqpg3k	72	26	inducing	induce	VBG
cord-263699-gosqpg3k	72	27	its	-PRON-	PRP$
cord-263699-gosqpg3k	72	28	conformational	conformational	JJ
cord-263699-gosqpg3k	72	29	change	change	NN
cord-263699-gosqpg3k	72	30	,	,	,
cord-263699-gosqpg3k	72	31	and	and	CC
cord-263699-gosqpg3k	72	32	promoting	promote	VBG
cord-263699-gosqpg3k	72	33	the	the	DT
cord-263699-gosqpg3k	72	34	exchange	exchange	NN
cord-263699-gosqpg3k	72	35	of	of	IN
cord-263699-gosqpg3k	72	36	GDP	GDP	NNP
cord-263699-gosqpg3k	72	37	for	for	IN
cord-263699-gosqpg3k	72	38	GTP	GTP	NNP
cord-263699-gosqpg3k	72	39	that	that	WDT
cord-263699-gosqpg3k	72	40	leads	lead	VBZ
cord-263699-gosqpg3k	72	41	to	to	IN
cord-263699-gosqpg3k	72	42	the	the	DT
cord-263699-gosqpg3k	72	43	dissociation	dissociation	NN
cord-263699-gosqpg3k	72	44	of	of	IN
cord-263699-gosqpg3k	72	45	the	the	DT
cord-263699-gosqpg3k	72	46	protein	protein	NN
cord-263699-gosqpg3k	72	47	from	from	IN
cord-263699-gosqpg3k	72	48	GBF1	GBF1	NNP
cord-263699-gosqpg3k	72	49	[	[	-LRB-
cord-263699-gosqpg3k	72	50	36	36	CD
cord-263699-gosqpg3k	72	51	,	,	,
cord-263699-gosqpg3k	72	52	37	37	CD
cord-263699-gosqpg3k	72	53	]	]	-RRB-
cord-263699-gosqpg3k	72	54	.	.	.
cord-263699-gosqpg3k	73	1	Through	through	IN
cord-263699-gosqpg3k	73	2	this	this	DT
cord-263699-gosqpg3k	73	3	mechanism	mechanism	NN
cord-263699-gosqpg3k	73	4	,	,	,
cord-263699-gosqpg3k	73	5	GBF1	GBF1	NNP
cord-263699-gosqpg3k	73	6	can	can	MD
cord-263699-gosqpg3k	73	7	activate	activate	VB
cord-263699-gosqpg3k	73	8	Arf1	Arf1	NNP
cord-263699-gosqpg3k	73	9	,	,	,
cord-263699-gosqpg3k	73	10	Arf4	Arf4	NNP
cord-263699-gosqpg3k	73	11	,	,	,
cord-263699-gosqpg3k	73	12	and	and	CC
cord-263699-gosqpg3k	73	13	Arf5	Arf5	NNP
cord-263699-gosqpg3k	73	14	[	[	-LRB-
cord-263699-gosqpg3k	73	15	38	38	CD
cord-263699-gosqpg3k	73	16	]	]	-RRB-
cord-263699-gosqpg3k	73	17	[	[	-LRB-
cord-263699-gosqpg3k	73	18	39	39	CD
cord-263699-gosqpg3k	73	19	]	]	-RRB-
cord-263699-gosqpg3k	73	20	[	[	-LRB-
cord-263699-gosqpg3k	73	21	40	40	CD
cord-263699-gosqpg3k	73	22	]	]	-RRB-
cord-263699-gosqpg3k	73	23	.	.	.
cord-263699-gosqpg3k	74	1	In	in	IN
cord-263699-gosqpg3k	74	2	addition	addition	NN
cord-263699-gosqpg3k	74	3	to	to	IN
cord-263699-gosqpg3k	74	4	its	-PRON-	PRP$
cord-263699-gosqpg3k	74	5	Sec7	Sec7	NNP
cord-263699-gosqpg3k	74	6	domain	domain	NN
cord-263699-gosqpg3k	74	7	,	,	,
cord-263699-gosqpg3k	74	8	GBF1	GBF1	NNP
cord-263699-gosqpg3k	74	9	contains	contain	VBZ
cord-263699-gosqpg3k	74	10	five	five	CD
cord-263699-gosqpg3k	74	11	non	non	JJ
cord-263699-gosqpg3k	74	12	-	-	JJ
cord-263699-gosqpg3k	74	13	catalytic	catalytic	JJ
cord-263699-gosqpg3k	74	14	domains	domain	NNS
cord-263699-gosqpg3k	74	15	:	:	:
cord-263699-gosqpg3k	74	16	the	the	DT
cord-263699-gosqpg3k	74	17	N	n	CD
cord-263699-gosqpg3k	74	18	-	-	HYPH
cord-263699-gosqpg3k	74	19	terminal	terminal	NN
cord-263699-gosqpg3k	74	20	dimerization	dimerization	NN
cord-263699-gosqpg3k	74	21	and	and	CC
cord-263699-gosqpg3k	74	22	cyclophilin	cyclophilin	NN
cord-263699-gosqpg3k	74	23	binding	bind	VBG
cord-263699-gosqpg3k	74	24	(	(	-LRB-
cord-263699-gosqpg3k	74	25	DCB	DCB	NNP
cord-263699-gosqpg3k	74	26	)	)	-RRB-
cord-263699-gosqpg3k	74	27	domain	domain	NN
cord-263699-gosqpg3k	74	28	,	,	,
cord-263699-gosqpg3k	74	29	the	the	DT
cord-263699-gosqpg3k	74	30	homology	homology	NN
cord-263699-gosqpg3k	74	31	upstream	upstream	RB
cord-263699-gosqpg3k	74	32	of	of	IN
cord-263699-gosqpg3k	74	33	Sec7	Sec7	NNP
cord-263699-gosqpg3k	74	34	(	(	-LRB-
cord-263699-gosqpg3k	74	35	HUS	HUS	NNP
cord-263699-gosqpg3k	74	36	)	)	-RRB-
cord-263699-gosqpg3k	74	37	domain	domain	NN
cord-263699-gosqpg3k	74	38	,	,	,
cord-263699-gosqpg3k	74	39	and	and	CC
cord-263699-gosqpg3k	74	40	three	three	CD
cord-263699-gosqpg3k	74	41	C	c	NN
cord-263699-gosqpg3k	74	42	-	-	HYPH
cord-263699-gosqpg3k	74	43	terminal	terminal	NN
cord-263699-gosqpg3k	74	44	downstream	downstream	NN
cord-263699-gosqpg3k	74	45	of	of	IN
cord-263699-gosqpg3k	74	46	Sec7	Sec7	NNP
cord-263699-gosqpg3k	74	47	(	(	-LRB-
cord-263699-gosqpg3k	74	48	HDS1	HDS1	NNP
cord-263699-gosqpg3k	74	49	-	-	HYPH
cord-263699-gosqpg3k	74	50	3	3	CD
cord-263699-gosqpg3k	74	51	)	)	-RRB-
cord-263699-gosqpg3k	74	52	domains	domain	NNS
cord-263699-gosqpg3k	74	53	[	[	-LRB-
cord-263699-gosqpg3k	74	54	34	34	CD
cord-263699-gosqpg3k	74	55	,	,	,
cord-263699-gosqpg3k	74	56	41	41	CD
cord-263699-gosqpg3k	74	57	]	]	-RRB-
cord-263699-gosqpg3k	74	58	(	(	-LRB-
cord-263699-gosqpg3k	74	59	Figure	figure	NN
cord-263699-gosqpg3k	74	60	3	3	CD
cord-263699-gosqpg3k	74	61	)	)	-RRB-
cord-263699-gosqpg3k	74	62	.	.	.
cord-263699-gosqpg3k	75	1	The	the	DT
cord-263699-gosqpg3k	75	2	functions	function	NNS
cord-263699-gosqpg3k	75	3	of	of	IN
cord-263699-gosqpg3k	75	4	these	these	DT
cord-263699-gosqpg3k	75	5	non	non	JJ
cord-263699-gosqpg3k	75	6	-	-	JJ
cord-263699-gosqpg3k	75	7	catalytic	catalytic	JJ
cord-263699-gosqpg3k	75	8	domains	domain	NNS
cord-263699-gosqpg3k	75	9	are	be	VBP
cord-263699-gosqpg3k	75	10	not	not	RB
cord-263699-gosqpg3k	75	11	well	well	RB
cord-263699-gosqpg3k	75	12	understood	understand	VBN
cord-263699-gosqpg3k	75	13	,	,	,
cord-263699-gosqpg3k	75	14	but	but	CC
cord-263699-gosqpg3k	75	15	given	give	VBN
cord-263699-gosqpg3k	75	16	that	that	IN
cord-263699-gosqpg3k	75	17	GBF1	GBF1	NNP
cord-263699-gosqpg3k	75	18	cycles	cycle	NNS
cord-263699-gosqpg3k	75	19	between	between	IN
cord-263699-gosqpg3k	75	20	a	a	DT
cord-263699-gosqpg3k	75	21	soluble	soluble	JJ
cord-263699-gosqpg3k	75	22	and	and	CC
cord-263699-gosqpg3k	75	23	a	a	DT
cord-263699-gosqpg3k	75	24	membrane	membrane	NN
cord-263699-gosqpg3k	75	25	-	-	HYPH
cord-263699-gosqpg3k	75	26	bound	bind	VBN
cord-263699-gosqpg3k	75	27	state	state	NN
cord-263699-gosqpg3k	75	28	,	,	,
cord-263699-gosqpg3k	75	29	similar	similar	JJ
cord-263699-gosqpg3k	75	30	to	to	IN
cord-263699-gosqpg3k	75	31	Arf	Arf	NNP
cord-263699-gosqpg3k	75	32	proteins	protein	NNS
cord-263699-gosqpg3k	75	33	,	,	,
cord-263699-gosqpg3k	75	34	it	-PRON-	PRP
cord-263699-gosqpg3k	75	35	has	have	VBZ
cord-263699-gosqpg3k	75	36	been	be	VBN
cord-263699-gosqpg3k	75	37	proposed	propose	VBN
cord-263699-gosqpg3k	75	38	that	that	IN
cord-263699-gosqpg3k	75	39	these	these	DT
cord-263699-gosqpg3k	75	40	domains	domain	NNS
cord-263699-gosqpg3k	75	41	are	be	VBP
cord-263699-gosqpg3k	75	42	important	important	JJ
cord-263699-gosqpg3k	75	43	for	for	IN
cord-263699-gosqpg3k	75	44	the	the	DT
cord-263699-gosqpg3k	75	45	specific	specific	JJ
cord-263699-gosqpg3k	75	46	interaction	interaction	NN
cord-263699-gosqpg3k	75	47	of	of	IN
cord-263699-gosqpg3k	75	48	GBF1	GBF1	NNP
cord-263699-gosqpg3k	75	49	with	with	IN
cord-263699-gosqpg3k	75	50	cellular	cellular	JJ
cord-263699-gosqpg3k	75	51	membranes	membrane	NNS
cord-263699-gosqpg3k	75	52	[	[	-LRB-
cord-263699-gosqpg3k	75	53	35	35	CD
cord-263699-gosqpg3k	75	54	,	,	,
cord-263699-gosqpg3k	75	55	[	[	-LRB-
cord-263699-gosqpg3k	75	56	42	42	CD
cord-263699-gosqpg3k	75	57	]	]	-RRB-
cord-263699-gosqpg3k	75	58	[	[	-LRB-
cord-263699-gosqpg3k	75	59	43	43	CD
cord-263699-gosqpg3k	75	60	]	]	-RRB-
cord-263699-gosqpg3k	75	61	[	[	-LRB-
cord-263699-gosqpg3k	75	62	44	44	CD
cord-263699-gosqpg3k	75	63	]	]	-RRB-
cord-263699-gosqpg3k	75	64	.	.	.
cord-263699-gosqpg3k	76	1	[	[	-LRB-
cord-263699-gosqpg3k	76	2	34	34	CD
cord-263699-gosqpg3k	76	3	,	,	,
cord-263699-gosqpg3k	76	4	41	41	CD
cord-263699-gosqpg3k	76	5	]	]	-RRB-
cord-263699-gosqpg3k	76	6	(	(	-LRB-
cord-263699-gosqpg3k	76	7	Figure	figure	NN
cord-263699-gosqpg3k	76	8	3	3	CD
cord-263699-gosqpg3k	76	9	)	)	-RRB-
cord-263699-gosqpg3k	76	10	.	.	.
cord-263699-gosqpg3k	77	1	The	the	DT
cord-263699-gosqpg3k	77	2	functions	function	NNS
cord-263699-gosqpg3k	77	3	of	of	IN
cord-263699-gosqpg3k	77	4	these	these	DT
cord-263699-gosqpg3k	77	5	non	non	JJ
cord-263699-gosqpg3k	77	6	-	-	JJ
cord-263699-gosqpg3k	77	7	catalytic	catalytic	JJ
cord-263699-gosqpg3k	77	8	domains	domain	NNS
cord-263699-gosqpg3k	77	9	are	be	VBP
cord-263699-gosqpg3k	77	10	not	not	RB
cord-263699-gosqpg3k	77	11	well	well	RB
cord-263699-gosqpg3k	77	12	understood	understand	VBN
cord-263699-gosqpg3k	77	13	,	,	,
cord-263699-gosqpg3k	77	14	but	but	CC
cord-263699-gosqpg3k	77	15	given	give	VBN
cord-263699-gosqpg3k	77	16	that	that	IN
cord-263699-gosqpg3k	77	17	GBF1	GBF1	NNP
cord-263699-gosqpg3k	77	18	cycles	cycle	NNS
cord-263699-gosqpg3k	77	19	between	between	IN
cord-263699-gosqpg3k	77	20	a	a	DT
cord-263699-gosqpg3k	77	21	soluble	soluble	JJ
cord-263699-gosqpg3k	77	22	and	and	CC
cord-263699-gosqpg3k	77	23	a	a	DT
cord-263699-gosqpg3k	77	24	membranebound	membranebound	NN
cord-263699-gosqpg3k	77	25	state	state	NN
cord-263699-gosqpg3k	77	26	,	,	,
cord-263699-gosqpg3k	77	27	similar	similar	JJ
cord-263699-gosqpg3k	77	28	to	to	IN
cord-263699-gosqpg3k	77	29	Arf	Arf	NNP
cord-263699-gosqpg3k	77	30	proteins	protein	NNS
cord-263699-gosqpg3k	77	31	,	,	,
cord-263699-gosqpg3k	77	32	it	-PRON-	PRP
cord-263699-gosqpg3k	77	33	has	have	VBZ
cord-263699-gosqpg3k	77	34	been	be	VBN
cord-263699-gosqpg3k	77	35	proposed	propose	VBN
cord-263699-gosqpg3k	77	36	that	that	IN
cord-263699-gosqpg3k	77	37	these	these	DT
cord-263699-gosqpg3k	77	38	domains	domain	NNS
cord-263699-gosqpg3k	77	39	are	be	VBP
cord-263699-gosqpg3k	77	40	important	important	JJ
cord-263699-gosqpg3k	77	41	for	for	IN
cord-263699-gosqpg3k	77	42	the	the	DT
cord-263699-gosqpg3k	77	43	specific	specific	JJ
cord-263699-gosqpg3k	77	44	interaction	interaction	NN
cord-263699-gosqpg3k	77	45	of	of	IN
cord-263699-gosqpg3k	77	46	GBF1	GBF1	NNP
cord-263699-gosqpg3k	77	47	with	with	IN
cord-263699-gosqpg3k	77	48	cellular	cellular	JJ
cord-263699-gosqpg3k	77	49	membranes	membrane	NNS
cord-263699-gosqpg3k	77	50	[	[	-LRB-
cord-263699-gosqpg3k	77	51	35	35	CD
cord-263699-gosqpg3k	77	52	,	,	,
cord-263699-gosqpg3k	77	53	[	[	-LRB-
cord-263699-gosqpg3k	77	54	42	42	CD
cord-263699-gosqpg3k	77	55	]	]	-RRB-
cord-263699-gosqpg3k	77	56	[	[	-LRB-
cord-263699-gosqpg3k	77	57	43	43	CD
cord-263699-gosqpg3k	77	58	]	]	-RRB-
cord-263699-gosqpg3k	77	59	[	[	-LRB-
cord-263699-gosqpg3k	77	60	44	44	CD
cord-263699-gosqpg3k	77	61	]	]	-RRB-
cord-263699-gosqpg3k	77	62	.	.	.
cord-263699-gosqpg3k	78	1	The	the	DT
cord-263699-gosqpg3k	78	2	multidomain	multidomain	NN
cord-263699-gosqpg3k	78	3	structure	structure	NN
cord-263699-gosqpg3k	78	4	of	of	IN
cord-263699-gosqpg3k	78	5	GBF1	GBF1	NNP
cord-263699-gosqpg3k	78	6	allows	allow	VBZ
cord-263699-gosqpg3k	78	7	this	this	DT
cord-263699-gosqpg3k	78	8	protein	protein	NN
cord-263699-gosqpg3k	78	9	to	to	TO
cord-263699-gosqpg3k	78	10	engage	engage	VB
cord-263699-gosqpg3k	78	11	in	in	IN
cord-263699-gosqpg3k	78	12	numerous	numerous	JJ
cord-263699-gosqpg3k	78	13	interactions	interaction	NNS
cord-263699-gosqpg3k	78	14	with	with	IN
cord-263699-gosqpg3k	78	15	other	other	JJ
cord-263699-gosqpg3k	78	16	proteins	protein	NNS
cord-263699-gosqpg3k	78	17	,	,	,
cord-263699-gosqpg3k	78	18	leading	lead	VBG
cord-263699-gosqpg3k	78	19	GBF1	GBF1	NNP
cord-263699-gosqpg3k	78	20	to	to	TO
cord-263699-gosqpg3k	78	21	participate	participate	VB
cord-263699-gosqpg3k	78	22	in	in	IN
cord-263699-gosqpg3k	78	23	many	many	JJ
cord-263699-gosqpg3k	78	24	different	different	JJ
cord-263699-gosqpg3k	78	25	cellular	cellular	JJ
cord-263699-gosqpg3k	78	26	processes	process	NNS
cord-263699-gosqpg3k	78	27	and	and	CC
cord-263699-gosqpg3k	78	28	even	even	RB
cord-263699-gosqpg3k	78	29	in	in	IN
cord-263699-gosqpg3k	78	30	the	the	DT
cord-263699-gosqpg3k	78	31	process	process	NN
cord-263699-gosqpg3k	78	32	of	of	IN
cord-263699-gosqpg3k	78	33	infection	infection	NN
cord-263699-gosqpg3k	78	34	of	of	IN
cord-263699-gosqpg3k	78	35	some	some	DT
cord-263699-gosqpg3k	78	36	bacteria	bacteria	NNS
cord-263699-gosqpg3k	78	37	[	[	-LRB-
cord-263699-gosqpg3k	78	38	45	45	CD
cord-263699-gosqpg3k	78	39	,	,	,
cord-263699-gosqpg3k	78	40	46	46	CD
cord-263699-gosqpg3k	78	41	]	]	-RRB-
cord-263699-gosqpg3k	78	42	.	.	.
cord-263699-gosqpg3k	79	1	In	in	IN
cord-263699-gosqpg3k	79	2	addition	addition	NN
cord-263699-gosqpg3k	79	3	to	to	IN
cord-263699-gosqpg3k	79	4	its	-PRON-	PRP$
cord-263699-gosqpg3k	79	5	canonical	canonical	JJ
cord-263699-gosqpg3k	79	6	role	role	NN
cord-263699-gosqpg3k	79	7	in	in	IN
cord-263699-gosqpg3k	79	8	vesicular	vesicular	JJ
cord-263699-gosqpg3k	79	9	transport	transport	NN
cord-263699-gosqpg3k	79	10	,	,	,
cord-263699-gosqpg3k	79	11	GBF1	GBF1	NNP
cord-263699-gosqpg3k	79	12	has	have	VBZ
cord-263699-gosqpg3k	79	13	also	also	RB
cord-263699-gosqpg3k	79	14	been	be	VBN
cord-263699-gosqpg3k	79	15	shown	show	VBN
cord-263699-gosqpg3k	79	16	to	to	TO
cord-263699-gosqpg3k	79	17	participate	participate	VB
cord-263699-gosqpg3k	79	18	in	in	IN
cord-263699-gosqpg3k	79	19	the	the	DT
cord-263699-gosqpg3k	79	20	function	function	NN
cord-263699-gosqpg3k	79	21	of	of	IN
cord-263699-gosqpg3k	79	22	LDs	LDs	NNP
cord-263699-gosqpg3k	79	23	and	and	CC
cord-263699-gosqpg3k	79	24	mitochondria	mitochondrion	NNS
cord-263699-gosqpg3k	79	25	,	,	,
cord-263699-gosqpg3k	79	26	as	as	RB
cord-263699-gosqpg3k	79	27	well	well	RB
cord-263699-gosqpg3k	79	28	as	as	IN
cord-263699-gosqpg3k	79	29	in	in	IN
cord-263699-gosqpg3k	79	30	a	a	DT
cord-263699-gosqpg3k	79	31	clathrin	clathrin	NN
cord-263699-gosqpg3k	79	32	-	-	HYPH
cord-263699-gosqpg3k	79	33	independent	independent	JJ
cord-263699-gosqpg3k	79	34	endocytosis	endocytosis	NN
cord-263699-gosqpg3k	79	35	pathway	pathway	NN
cord-263699-gosqpg3k	79	36	and	and	CC
cord-263699-gosqpg3k	79	37	the	the	DT
cord-263699-gosqpg3k	79	38	chemotaxis	chemotaxis	NN
cord-263699-gosqpg3k	79	39	of	of	IN
cord-263699-gosqpg3k	79	40	migrating	migrate	VBG
cord-263699-gosqpg3k	79	41	neutrophils	neutrophil	NNS
cord-263699-gosqpg3k	79	42	[	[	-LRB-
cord-263699-gosqpg3k	79	43	34	34	CD
cord-263699-gosqpg3k	79	44	]	]	-RRB-
cord-263699-gosqpg3k	79	45	.	.	.
cord-263699-gosqpg3k	80	1	Many	many	JJ
cord-263699-gosqpg3k	80	2	of	of	IN
cord-263699-gosqpg3k	80	3	these	these	DT
cord-263699-gosqpg3k	80	4	functions	function	NNS
cord-263699-gosqpg3k	80	5	have	have	VBP
cord-263699-gosqpg3k	80	6	been	be	VBN
cord-263699-gosqpg3k	80	7	elucidated	elucidate	VBN
cord-263699-gosqpg3k	80	8	through	through	IN
cord-263699-gosqpg3k	80	9	the	the	DT
cord-263699-gosqpg3k	80	10	use	use	NN
cord-263699-gosqpg3k	80	11	of	of	IN
cord-263699-gosqpg3k	80	12	the	the	DT
cord-263699-gosqpg3k	80	13	fungal	fungal	JJ
cord-263699-gosqpg3k	80	14	toxin	toxin	NN
cord-263699-gosqpg3k	80	15	Brefeldin	Brefeldin	NNP
cord-263699-gosqpg3k	80	16	A	A	NNP
cord-263699-gosqpg3k	80	17	(	(	-LRB-
cord-263699-gosqpg3k	80	18	BFA	BFA	NNP
cord-263699-gosqpg3k	80	19	)	)	-RRB-
cord-263699-gosqpg3k	80	20	and	and	CC
cord-263699-gosqpg3k	80	21	the	the	DT
cord-263699-gosqpg3k	80	22	small	small	JJ
cord-263699-gosqpg3k	80	23	-	-	HYPH
cord-263699-gosqpg3k	80	24	molecule	molecule	NN
cord-263699-gosqpg3k	80	25	Golgicide	Golgicide	NNP
cord-263699-gosqpg3k	80	26	A	A	NNP
cord-263699-gosqpg3k	80	27	(	(	-LRB-
cord-263699-gosqpg3k	80	28	GCA	GCA	NNP
cord-263699-gosqpg3k	80	29	)	)	-RRB-
cord-263699-gosqpg3k	80	30	,	,	,
cord-263699-gosqpg3k	80	31	which	which	WDT
cord-263699-gosqpg3k	80	32	inhibit	inhibit	VBP
cord-263699-gosqpg3k	80	33	the	the	DT
cord-263699-gosqpg3k	80	34	catalytic	catalytic	JJ
cord-263699-gosqpg3k	80	35	activity	activity	NN
cord-263699-gosqpg3k	80	36	of	of	IN
cord-263699-gosqpg3k	80	37	this	this	DT
cord-263699-gosqpg3k	80	38	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	80	39	exchange	exchange	NN
cord-263699-gosqpg3k	80	40	factor	factor	NN
cord-263699-gosqpg3k	80	41	.	.	.
cord-263699-gosqpg3k	81	1	These	these	DT
cord-263699-gosqpg3k	81	2	inhibitors	inhibitor	NNS
cord-263699-gosqpg3k	81	3	bind	bind	VBP
cord-263699-gosqpg3k	81	4	to	to	IN
cord-263699-gosqpg3k	81	5	the	the	DT
cord-263699-gosqpg3k	81	6	protein	protein	NN
cord-263699-gosqpg3k	81	7	-	-	HYPH
cord-263699-gosqpg3k	81	8	protein	protein	NN
cord-263699-gosqpg3k	81	9	interface	interface	NN
cord-263699-gosqpg3k	81	10	in	in	IN
cord-263699-gosqpg3k	81	11	the	the	DT
cord-263699-gosqpg3k	81	12	complex	complex	NN
cord-263699-gosqpg3k	81	13	formed	form	VBN
cord-263699-gosqpg3k	81	14	by	by	IN
cord-263699-gosqpg3k	81	15	the	the	DT
cord-263699-gosqpg3k	81	16	Sec7	Sec7	NNP
cord-263699-gosqpg3k	81	17	domain	domain	NN
cord-263699-gosqpg3k	81	18	of	of	IN
cord-263699-gosqpg3k	81	19	GBF1	GBF1	NNP
cord-263699-gosqpg3k	81	20	and	and	CC
cord-263699-gosqpg3k	81	21	Arf	Arf	NNP
cord-263699-gosqpg3k	81	22	-	-	HYPH
cord-263699-gosqpg3k	81	23	GDP	GDP	NNP
cord-263699-gosqpg3k	81	24	,	,	,
cord-263699-gosqpg3k	81	25	and	and	CC
cord-263699-gosqpg3k	81	26	block	block	VB
cord-263699-gosqpg3k	81	27	the	the	DT
cord-263699-gosqpg3k	81	28	conformational	conformational	JJ
cord-263699-gosqpg3k	81	29	changes	change	NNS
cord-263699-gosqpg3k	81	30	of	of	IN
cord-263699-gosqpg3k	81	31	Arf	Arf	NNP
cord-263699-gosqpg3k	81	32	proteins	protein	NNS
cord-263699-gosqpg3k	81	33	that	that	WDT
cord-263699-gosqpg3k	81	34	allow	allow	VBP
cord-263699-gosqpg3k	81	35	the	the	DT
cord-263699-gosqpg3k	81	36	exchange	exchange	NN
cord-263699-gosqpg3k	81	37	of	of	IN
cord-263699-gosqpg3k	81	38	GDP	GDP	NNP
cord-263699-gosqpg3k	81	39	for	for	IN
cord-263699-gosqpg3k	81	40	GTP	GTP	NNP
cord-263699-gosqpg3k	81	41	[	[	-LRB-
cord-263699-gosqpg3k	81	42	36	36	CD
cord-263699-gosqpg3k	81	43	]	]	-RRB-
cord-263699-gosqpg3k	81	44	.	.	.
cord-263699-gosqpg3k	82	1	This	this	DT
cord-263699-gosqpg3k	82	2	inhibition	inhibition	NN
cord-263699-gosqpg3k	82	3	leads	lead	VBZ
cord-263699-gosqpg3k	82	4	to	to	IN
cord-263699-gosqpg3k	82	5	the	the	DT
cord-263699-gosqpg3k	82	6	release	release	NN
cord-263699-gosqpg3k	82	7	of	of	IN
cord-263699-gosqpg3k	82	8	COPI	COPI	NNP
cord-263699-gosqpg3k	82	9	from	from	IN
cord-263699-gosqpg3k	82	10	the	the	DT
cord-263699-gosqpg3k	82	11	membranes	membrane	NNS
cord-263699-gosqpg3k	82	12	with	with	IN
cord-263699-gosqpg3k	82	13	the	the	DT
cord-263699-gosqpg3k	82	14	consequent	consequent	JJ
cord-263699-gosqpg3k	82	15	inhibition	inhibition	NN
cord-263699-gosqpg3k	82	16	of	of	IN
cord-263699-gosqpg3k	82	17	the	the	DT
cord-263699-gosqpg3k	82	18	vesicle	vesicle	NN
cord-263699-gosqpg3k	82	19	transport	transport	NN
cord-263699-gosqpg3k	82	20	,	,	,
cord-263699-gosqpg3k	82	21	and	and	CC
cord-263699-gosqpg3k	82	22	also	also	RB
cord-263699-gosqpg3k	82	23	primes	prime	VBZ
cord-263699-gosqpg3k	82	24	the	the	DT
cord-263699-gosqpg3k	82	25	disassembly	disassembly	NN
cord-263699-gosqpg3k	82	26	of	of	IN
cord-263699-gosqpg3k	82	27	the	the	DT
cord-263699-gosqpg3k	82	28	cisternae	cisternae	NN
cord-263699-gosqpg3k	82	29	of	of	IN
cord-263699-gosqpg3k	82	30	the	the	DT
cord-263699-gosqpg3k	82	31	Golgi	Golgi	NNP
cord-263699-gosqpg3k	82	32	apparatus	apparatus	NN
cord-263699-gosqpg3k	82	33	.	.	.
cord-263699-gosqpg3k	83	1	Moreover	moreover	RB
cord-263699-gosqpg3k	83	2	,	,	,
cord-263699-gosqpg3k	83	3	it	-PRON-	PRP
cord-263699-gosqpg3k	83	4	has	have	VBZ
cord-263699-gosqpg3k	83	5	also	also	RB
cord-263699-gosqpg3k	83	6	been	be	VBN
cord-263699-gosqpg3k	83	7	observed	observe	VBN
cord-263699-gosqpg3k	83	8	that	that	IN
cord-263699-gosqpg3k	83	9	BFA	BFA	NNP
cord-263699-gosqpg3k	83	10	and	and	CC
cord-263699-gosqpg3k	83	11	GCA	GCA	NNP
cord-263699-gosqpg3k	83	12	induce	induce	VBP
cord-263699-gosqpg3k	83	13	the	the	DT
cord-263699-gosqpg3k	83	14	swelling	swelling	NN
cord-263699-gosqpg3k	83	15	of	of	IN
cord-263699-gosqpg3k	83	16	the	the	DT
cord-263699-gosqpg3k	83	17	ER	ER	NNP
cord-263699-gosqpg3k	83	18	compartment	compartment	NN
cord-263699-gosqpg3k	83	19	,	,	,
cord-263699-gosqpg3k	83	20	likely	likely	RB
cord-263699-gosqpg3k	83	21	due	due	IN
cord-263699-gosqpg3k	83	22	to	to	IN
cord-263699-gosqpg3k	83	23	the	the	DT
cord-263699-gosqpg3k	83	24	fusion	fusion	NN
cord-263699-gosqpg3k	83	25	of	of	IN
cord-263699-gosqpg3k	83	26	the	the	DT
cord-263699-gosqpg3k	83	27	cis	cis	NNP
cord-263699-gosqpg3k	83	28	-	-	HYPH
cord-263699-gosqpg3k	83	29	Golgi	Golgi	NNP
cord-263699-gosqpg3k	83	30	with	with	IN
cord-263699-gosqpg3k	83	31	the	the	DT
cord-263699-gosqpg3k	83	32	ER	er	NN
cord-263699-gosqpg3k	83	33	.	.	.
cord-263699-gosqpg3k	84	1	Both	both	DT
cord-263699-gosqpg3k	84	2	BFA	BFA	NNP
cord-263699-gosqpg3k	84	3	and	and	CC
cord-263699-gosqpg3k	84	4	GCA	GCA	NNP
cord-263699-gosqpg3k	84	5	share	share	VBP
cord-263699-gosqpg3k	84	6	many	many	JJ
cord-263699-gosqpg3k	84	7	similitudes	similitude	NNS
cord-263699-gosqpg3k	84	8	in	in	IN
cord-263699-gosqpg3k	84	9	their	-PRON-	PRP$
cord-263699-gosqpg3k	84	10	effects	effect	NNS
cord-263699-gosqpg3k	84	11	;	;	:
cord-263699-gosqpg3k	84	12	however	however	RB
cord-263699-gosqpg3k	84	13	,	,	,
cord-263699-gosqpg3k	84	14	while	while	IN
cord-263699-gosqpg3k	84	15	BFA	BFA	NNP
cord-263699-gosqpg3k	84	16	has	have	VBZ
cord-263699-gosqpg3k	84	17	been	be	VBN
cord-263699-gosqpg3k	84	18	shown	show	VBN
cord-263699-gosqpg3k	84	19	to	to	TO
cord-263699-gosqpg3k	84	20	inhibit	inhibit	VB
cord-263699-gosqpg3k	84	21	the	the	DT
cord-263699-gosqpg3k	84	22	activity	activity	NN
cord-263699-gosqpg3k	84	23	of	of	IN
cord-263699-gosqpg3k	84	24	GBF1	GBF1	NNP
cord-263699-gosqpg3k	84	25	,	,	,
cord-263699-gosqpg3k	84	26	BIG1	BIG1	NNP
cord-263699-gosqpg3k	84	27	,	,	,
cord-263699-gosqpg3k	84	28	and	and	CC
cord-263699-gosqpg3k	84	29	BIG2	BIG2	NNP
cord-263699-gosqpg3k	84	30	GEFs	gefs	NN
cord-263699-gosqpg3k	84	31	,	,	,
cord-263699-gosqpg3k	84	32	GCA	GCA	NNP
cord-263699-gosqpg3k	84	33	does	do	VBZ
cord-263699-gosqpg3k	84	34	not	not	RB
cord-263699-gosqpg3k	84	35	affect	affect	VB
cord-263699-gosqpg3k	84	36	other	other	JJ
cord-263699-gosqpg3k	84	37	GEFs	gefs	NN
cord-263699-gosqpg3k	84	38	as	as	IN
cord-263699-gosqpg3k	84	39	it	-PRON-	PRP
cord-263699-gosqpg3k	84	40	is	be	VBZ
cord-263699-gosqpg3k	84	41	a	a	DT
cord-263699-gosqpg3k	84	42	specific	specific	JJ
cord-263699-gosqpg3k	84	43	inhibitor	inhibitor	NN
cord-263699-gosqpg3k	84	44	of	of	IN
cord-263699-gosqpg3k	84	45	GBF1	GBF1	NNP
cord-263699-gosqpg3k	84	46	[	[	-LRB-
cord-263699-gosqpg3k	84	47	15	15	CD
cord-263699-gosqpg3k	84	48	,	,	,
cord-263699-gosqpg3k	84	49	32	32	CD
cord-263699-gosqpg3k	84	50	,	,	,
cord-263699-gosqpg3k	84	51	33	33	CD
cord-263699-gosqpg3k	84	52	,	,	,
cord-263699-gosqpg3k	84	53	47	47	CD
cord-263699-gosqpg3k	84	54	]	]	-RRB-
cord-263699-gosqpg3k	84	55	.	.	.
cord-263699-gosqpg3k	85	1	These	these	DT
cord-263699-gosqpg3k	85	2	inhibitors	inhibitor	NNS
cord-263699-gosqpg3k	85	3	have	have	VBP
cord-263699-gosqpg3k	85	4	been	be	VBN
cord-263699-gosqpg3k	85	5	useful	useful	JJ
cord-263699-gosqpg3k	85	6	tools	tool	NNS
cord-263699-gosqpg3k	85	7	for	for	IN
cord-263699-gosqpg3k	85	8	understanding	understand	VBG
cord-263699-gosqpg3k	85	9	the	the	DT
cord-263699-gosqpg3k	85	10	participation	participation	NN
cord-263699-gosqpg3k	85	11	of	of	IN
cord-263699-gosqpg3k	85	12	GBF1	GBF1	NNP
cord-263699-gosqpg3k	85	13	in	in	IN
cord-263699-gosqpg3k	85	14	different	different	JJ
cord-263699-gosqpg3k	85	15	cellular	cellular	JJ
cord-263699-gosqpg3k	85	16	functions	function	NNS
cord-263699-gosqpg3k	85	17	.	.	.
cord-263699-gosqpg3k	86	1	Moreover	moreover	RB
cord-263699-gosqpg3k	86	2	,	,	,
cord-263699-gosqpg3k	86	3	in	in	IN
cord-263699-gosqpg3k	86	4	recent	recent	JJ
cord-263699-gosqpg3k	86	5	years	year	NNS
cord-263699-gosqpg3k	86	6	,	,	,
cord-263699-gosqpg3k	86	7	the	the	DT
cord-263699-gosqpg3k	86	8	use	use	NN
cord-263699-gosqpg3k	86	9	of	of	IN
cord-263699-gosqpg3k	86	10	these	these	DT
cord-263699-gosqpg3k	86	11	drugs	drug	NNS
cord-263699-gosqpg3k	86	12	has	have	VBZ
cord-263699-gosqpg3k	86	13	unveiled	unveil	VBN
cord-263699-gosqpg3k	86	14	the	the	DT
cord-263699-gosqpg3k	86	15	essential	essential	JJ
cord-263699-gosqpg3k	86	16	role	role	NN
cord-263699-gosqpg3k	86	17	that	that	WDT
cord-263699-gosqpg3k	86	18	GBF1	GBF1	NNP
cord-263699-gosqpg3k	86	19	plays	play	VBZ
cord-263699-gosqpg3k	86	20	in	in	IN
cord-263699-gosqpg3k	86	21	the	the	DT
cord-263699-gosqpg3k	86	22	replication	replication	NN
cord-263699-gosqpg3k	86	23	of	of	IN
cord-263699-gosqpg3k	86	24	several	several	JJ
cord-263699-gosqpg3k	86	25	RNA	RNA	NNP
cord-263699-gosqpg3k	86	26	viruses	virus	NNS
cord-263699-gosqpg3k	86	27	that	that	WDT
cord-263699-gosqpg3k	86	28	belong	belong	VBP
cord-263699-gosqpg3k	86	29	to	to	IN
cord-263699-gosqpg3k	86	30	different	different	JJ
cord-263699-gosqpg3k	86	31	families	family	NNS
cord-263699-gosqpg3k	86	32	(	(	-LRB-
cord-263699-gosqpg3k	86	33	Table	table	NN
cord-263699-gosqpg3k	86	34	1	1	CD
cord-263699-gosqpg3k	86	35	)	)	-RRB-
cord-263699-gosqpg3k	86	36	,	,	,
cord-263699-gosqpg3k	86	37	strongly	strongly	RB
cord-263699-gosqpg3k	86	38	suggesting	suggest	VBG
cord-263699-gosqpg3k	86	39	that	that	IN
cord-263699-gosqpg3k	86	40	GBF1	GBF1	NNP
cord-263699-gosqpg3k	86	41	can	can	MD
cord-263699-gosqpg3k	86	42	exhibit	exhibit	VB
cord-263699-gosqpg3k	86	43	diverse	diverse	JJ
cord-263699-gosqpg3k	86	44	functions	function	NNS
cord-263699-gosqpg3k	86	45	that	that	WDT
cord-263699-gosqpg3k	86	46	go	go	VBP
cord-263699-gosqpg3k	86	47	beyond	beyond	IN
cord-263699-gosqpg3k	86	48	its	-PRON-	PRP$
cord-263699-gosqpg3k	86	49	role	role	NN
cord-263699-gosqpg3k	86	50	in	in	IN
cord-263699-gosqpg3k	86	51	vesicle	vesicle	NN
cord-263699-gosqpg3k	86	52	transport	transport	NN
cord-263699-gosqpg3k	86	53	.	.	.
cord-263699-gosqpg3k	87	1	In	in	IN
cord-263699-gosqpg3k	87	2	this	this	DT
cord-263699-gosqpg3k	87	3	review	review	NN
cord-263699-gosqpg3k	87	4	,	,	,
cord-263699-gosqpg3k	87	5	we	-PRON-	PRP
cord-263699-gosqpg3k	87	6	explore	explore	VBP
cord-263699-gosqpg3k	87	7	the	the	DT
cord-263699-gosqpg3k	87	8	current	current	JJ
cord-263699-gosqpg3k	87	9	knowledge	knowledge	NN
cord-263699-gosqpg3k	87	10	of	of	IN
cord-263699-gosqpg3k	87	11	the	the	DT
cord-263699-gosqpg3k	87	12	role	role	NN
cord-263699-gosqpg3k	87	13	GBF1	GBF1	NNP
cord-263699-gosqpg3k	87	14	plays	play	VBZ
cord-263699-gosqpg3k	87	15	in	in	IN
cord-263699-gosqpg3k	87	16	the	the	DT
cord-263699-gosqpg3k	87	17	replication	replication	NN
cord-263699-gosqpg3k	87	18	of	of	IN
cord-263699-gosqpg3k	87	19	RNA	RNA	NNP
cord-263699-gosqpg3k	87	20	viruses	virus	NNS
cord-263699-gosqpg3k	87	21	and	and	CC
cord-263699-gosqpg3k	87	22	present	present	VBP
cord-263699-gosqpg3k	87	23	an	an	DT
cord-263699-gosqpg3k	87	24	overview	overview	NN
cord-263699-gosqpg3k	87	25	of	of	IN
cord-263699-gosqpg3k	87	26	the	the	DT
cord-263699-gosqpg3k	87	27	different	different	JJ
cord-263699-gosqpg3k	87	28	viral	viral	JJ
cord-263699-gosqpg3k	87	29	functions	function	NNS
cord-263699-gosqpg3k	87	30	that	that	WDT
cord-263699-gosqpg3k	87	31	depend	depend	VBP
cord-263699-gosqpg3k	87	32	on	on	IN
cord-263699-gosqpg3k	87	33	the	the	DT
cord-263699-gosqpg3k	87	34	activity	activity	NN
cord-263699-gosqpg3k	87	35	of	of	IN
cord-263699-gosqpg3k	87	36	this	this	DT
cord-263699-gosqpg3k	87	37	factor	factor	NN
cord-263699-gosqpg3k	87	38	.	.	.
cord-263699-gosqpg3k	88	1	The	the	DT
cord-263699-gosqpg3k	88	2	multidomain	multidomain	NN
cord-263699-gosqpg3k	88	3	structure	structure	NN
cord-263699-gosqpg3k	88	4	of	of	IN
cord-263699-gosqpg3k	88	5	GBF1	GBF1	NNP
cord-263699-gosqpg3k	88	6	allows	allow	VBZ
cord-263699-gosqpg3k	88	7	this	this	DT
cord-263699-gosqpg3k	88	8	protein	protein	NN
cord-263699-gosqpg3k	88	9	to	to	TO
cord-263699-gosqpg3k	88	10	engage	engage	VB
cord-263699-gosqpg3k	88	11	in	in	IN
cord-263699-gosqpg3k	88	12	numerous	numerous	JJ
cord-263699-gosqpg3k	88	13	interactions	interaction	NNS
cord-263699-gosqpg3k	88	14	with	with	IN
cord-263699-gosqpg3k	88	15	other	other	JJ
cord-263699-gosqpg3k	88	16	proteins	protein	NNS
cord-263699-gosqpg3k	88	17	,	,	,
cord-263699-gosqpg3k	88	18	leading	lead	VBG
cord-263699-gosqpg3k	88	19	GBF1	GBF1	NNP
cord-263699-gosqpg3k	88	20	to	to	TO
cord-263699-gosqpg3k	88	21	participate	participate	VB
cord-263699-gosqpg3k	88	22	in	in	IN
cord-263699-gosqpg3k	88	23	many	many	JJ
cord-263699-gosqpg3k	88	24	different	different	JJ
cord-263699-gosqpg3k	88	25	cellular	cellular	JJ
cord-263699-gosqpg3k	88	26	processes	process	NNS
cord-263699-gosqpg3k	88	27	and	and	CC
cord-263699-gosqpg3k	88	28	even	even	RB
cord-263699-gosqpg3k	88	29	in	in	IN
cord-263699-gosqpg3k	88	30	the	the	DT
cord-263699-gosqpg3k	88	31	process	process	NN
cord-263699-gosqpg3k	88	32	of	of	IN
cord-263699-gosqpg3k	88	33	infection	infection	NN
cord-263699-gosqpg3k	88	34	of	of	IN
cord-263699-gosqpg3k	88	35	some	some	DT
cord-263699-gosqpg3k	88	36	bacteria	bacteria	NNS
cord-263699-gosqpg3k	88	37	[	[	-LRB-
cord-263699-gosqpg3k	88	38	45	45	CD
cord-263699-gosqpg3k	88	39	,	,	,
cord-263699-gosqpg3k	88	40	46	46	CD
cord-263699-gosqpg3k	88	41	]	]	-RRB-
cord-263699-gosqpg3k	88	42	.	.	.
cord-263699-gosqpg3k	89	1	In	in	IN
cord-263699-gosqpg3k	89	2	addition	addition	NN
cord-263699-gosqpg3k	89	3	to	to	IN
cord-263699-gosqpg3k	89	4	its	-PRON-	PRP$
cord-263699-gosqpg3k	89	5	canonical	canonical	JJ
cord-263699-gosqpg3k	89	6	role	role	NN
cord-263699-gosqpg3k	89	7	in	in	IN
cord-263699-gosqpg3k	89	8	vesicular	vesicular	JJ
cord-263699-gosqpg3k	89	9	transport	transport	NN
cord-263699-gosqpg3k	89	10	,	,	,
cord-263699-gosqpg3k	89	11	GBF1	GBF1	NNP
cord-263699-gosqpg3k	89	12	has	have	VBZ
cord-263699-gosqpg3k	89	13	also	also	RB
cord-263699-gosqpg3k	89	14	been	be	VBN
cord-263699-gosqpg3k	89	15	shown	show	VBN
cord-263699-gosqpg3k	89	16	to	to	TO
cord-263699-gosqpg3k	89	17	participate	participate	VB
cord-263699-gosqpg3k	89	18	in	in	IN
cord-263699-gosqpg3k	89	19	the	the	DT
cord-263699-gosqpg3k	89	20	function	function	NN
cord-263699-gosqpg3k	89	21	of	of	IN
cord-263699-gosqpg3k	89	22	LDs	LDs	NNP
cord-263699-gosqpg3k	89	23	and	and	CC
cord-263699-gosqpg3k	89	24	mitochondria	mitochondrion	NNS
cord-263699-gosqpg3k	89	25	,	,	,
cord-263699-gosqpg3k	89	26	as	as	RB
cord-263699-gosqpg3k	89	27	well	well	RB
cord-263699-gosqpg3k	89	28	as	as	IN
cord-263699-gosqpg3k	89	29	in	in	IN
cord-263699-gosqpg3k	89	30	a	a	DT
cord-263699-gosqpg3k	89	31	clathrin	clathrin	NN
cord-263699-gosqpg3k	89	32	-	-	HYPH
cord-263699-gosqpg3k	89	33	independent	independent	JJ
cord-263699-gosqpg3k	89	34	endocytosis	endocytosis	NN
cord-263699-gosqpg3k	89	35	pathway	pathway	NN
cord-263699-gosqpg3k	89	36	and	and	CC
cord-263699-gosqpg3k	89	37	the	the	DT
cord-263699-gosqpg3k	89	38	chemotaxis	chemotaxis	NN
cord-263699-gosqpg3k	89	39	of	of	IN
cord-263699-gosqpg3k	89	40	migrating	migrate	VBG
cord-263699-gosqpg3k	89	41	neutrophils	neutrophil	NNS
cord-263699-gosqpg3k	89	42	[	[	-LRB-
cord-263699-gosqpg3k	89	43	34	34	CD
cord-263699-gosqpg3k	89	44	]	]	-RRB-
cord-263699-gosqpg3k	89	45	.	.	.
cord-263699-gosqpg3k	90	1	Many	many	JJ
cord-263699-gosqpg3k	90	2	of	of	IN
cord-263699-gosqpg3k	90	3	these	these	DT
cord-263699-gosqpg3k	90	4	functions	function	NNS
cord-263699-gosqpg3k	90	5	have	have	VBP
cord-263699-gosqpg3k	90	6	been	be	VBN
cord-263699-gosqpg3k	90	7	elucidated	elucidate	VBN
cord-263699-gosqpg3k	90	8	through	through	IN
cord-263699-gosqpg3k	90	9	the	the	DT
cord-263699-gosqpg3k	90	10	use	use	NN
cord-263699-gosqpg3k	90	11	of	of	IN
cord-263699-gosqpg3k	90	12	the	the	DT
cord-263699-gosqpg3k	90	13	fungal	fungal	JJ
cord-263699-gosqpg3k	90	14	toxin	toxin	NN
cord-263699-gosqpg3k	90	15	Brefeldin	Brefeldin	NNP
cord-263699-gosqpg3k	90	16	A	A	NNP
cord-263699-gosqpg3k	90	17	(	(	-LRB-
cord-263699-gosqpg3k	90	18	BFA	BFA	NNP
cord-263699-gosqpg3k	90	19	)	)	-RRB-
cord-263699-gosqpg3k	90	20	and	and	CC
cord-263699-gosqpg3k	90	21	the	the	DT
cord-263699-gosqpg3k	90	22	small	small	JJ
cord-263699-gosqpg3k	90	23	-	-	HYPH
cord-263699-gosqpg3k	90	24	molecule	molecule	NN
cord-263699-gosqpg3k	90	25	Golgicide	Golgicide	NNP
cord-263699-gosqpg3k	90	26	A	A	NNP
cord-263699-gosqpg3k	90	27	(	(	-LRB-
cord-263699-gosqpg3k	90	28	GCA	GCA	NNP
cord-263699-gosqpg3k	90	29	)	)	-RRB-
cord-263699-gosqpg3k	90	30	,	,	,
cord-263699-gosqpg3k	90	31	which	which	WDT
cord-263699-gosqpg3k	90	32	inhibit	inhibit	VBP
cord-263699-gosqpg3k	90	33	the	the	DT
cord-263699-gosqpg3k	90	34	catalytic	catalytic	JJ
cord-263699-gosqpg3k	90	35	activity	activity	NN
cord-263699-gosqpg3k	90	36	of	of	IN
cord-263699-gosqpg3k	90	37	this	this	DT
cord-263699-gosqpg3k	90	38	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	90	39	exchange	exchange	NN
cord-263699-gosqpg3k	90	40	factor	factor	NN
cord-263699-gosqpg3k	90	41	.	.	.
cord-263699-gosqpg3k	91	1	These	these	DT
cord-263699-gosqpg3k	91	2	inhibitors	inhibitor	NNS
cord-263699-gosqpg3k	91	3	bind	bind	VBP
cord-263699-gosqpg3k	91	4	to	to	IN
cord-263699-gosqpg3k	91	5	the	the	DT
cord-263699-gosqpg3k	91	6	protein	protein	NN
cord-263699-gosqpg3k	91	7	-	-	HYPH
cord-263699-gosqpg3k	91	8	protein	protein	NN
cord-263699-gosqpg3k	91	9	interface	interface	NN
cord-263699-gosqpg3k	91	10	in	in	IN
cord-263699-gosqpg3k	91	11	the	the	DT
cord-263699-gosqpg3k	91	12	complex	complex	NN
cord-263699-gosqpg3k	91	13	formed	form	VBN
cord-263699-gosqpg3k	91	14	by	by	IN
cord-263699-gosqpg3k	91	15	the	the	DT
cord-263699-gosqpg3k	91	16	Sec7	Sec7	NNP
cord-263699-gosqpg3k	91	17	domain	domain	NN
cord-263699-gosqpg3k	91	18	of	of	IN
cord-263699-gosqpg3k	91	19	GBF1	GBF1	NNP
cord-263699-gosqpg3k	91	20	and	and	CC
cord-263699-gosqpg3k	91	21	Arf	Arf	NNP
cord-263699-gosqpg3k	91	22	-	-	HYPH
cord-263699-gosqpg3k	91	23	GDP	GDP	NNP
cord-263699-gosqpg3k	91	24	,	,	,
cord-263699-gosqpg3k	91	25	and	and	CC
cord-263699-gosqpg3k	91	26	block	block	VB
cord-263699-gosqpg3k	91	27	the	the	DT
cord-263699-gosqpg3k	91	28	conformational	conformational	JJ
cord-263699-gosqpg3k	91	29	changes	change	NNS
cord-263699-gosqpg3k	91	30	of	of	IN
cord-263699-gosqpg3k	91	31	Arf	Arf	NNP
cord-263699-gosqpg3k	91	32	proteins	protein	NNS
cord-263699-gosqpg3k	91	33	that	that	WDT
cord-263699-gosqpg3k	91	34	allow	allow	VBP
cord-263699-gosqpg3k	91	35	the	the	DT
cord-263699-gosqpg3k	91	36	exchange	exchange	NN
cord-263699-gosqpg3k	91	37	of	of	IN
cord-263699-gosqpg3k	91	38	GDP	GDP	NNP
cord-263699-gosqpg3k	91	39	for	for	IN
cord-263699-gosqpg3k	91	40	GTP	GTP	NNP
cord-263699-gosqpg3k	91	41	[	[	-LRB-
cord-263699-gosqpg3k	91	42	36	36	CD
cord-263699-gosqpg3k	91	43	]	]	-RRB-
cord-263699-gosqpg3k	91	44	.	.	.
cord-263699-gosqpg3k	92	1	This	this	DT
cord-263699-gosqpg3k	92	2	inhibition	inhibition	NN
cord-263699-gosqpg3k	92	3	leads	lead	VBZ
cord-263699-gosqpg3k	92	4	to	to	IN
cord-263699-gosqpg3k	92	5	the	the	DT
cord-263699-gosqpg3k	92	6	release	release	NN
cord-263699-gosqpg3k	92	7	of	of	IN
cord-263699-gosqpg3k	92	8	COPI	COPI	NNP
cord-263699-gosqpg3k	92	9	from	from	IN
cord-263699-gosqpg3k	92	10	the	the	DT
cord-263699-gosqpg3k	92	11	membranes	membrane	NNS
cord-263699-gosqpg3k	92	12	with	with	IN
cord-263699-gosqpg3k	92	13	the	the	DT
cord-263699-gosqpg3k	92	14	consequent	consequent	JJ
cord-263699-gosqpg3k	92	15	inhibition	inhibition	NN
cord-263699-gosqpg3k	92	16	of	of	IN
cord-263699-gosqpg3k	92	17	the	the	DT
cord-263699-gosqpg3k	92	18	vesicle	vesicle	NN
cord-263699-gosqpg3k	92	19	transport	transport	NN
cord-263699-gosqpg3k	92	20	,	,	,
cord-263699-gosqpg3k	92	21	and	and	CC
cord-263699-gosqpg3k	92	22	also	also	RB
cord-263699-gosqpg3k	92	23	primes	prime	VBZ
cord-263699-gosqpg3k	92	24	the	the	DT
cord-263699-gosqpg3k	92	25	disassembly	disassembly	NN
cord-263699-gosqpg3k	92	26	of	of	IN
cord-263699-gosqpg3k	92	27	the	the	DT
cord-263699-gosqpg3k	92	28	cisternae	cisternae	NN
cord-263699-gosqpg3k	92	29	of	of	IN
cord-263699-gosqpg3k	92	30	the	the	DT
cord-263699-gosqpg3k	92	31	Golgi	Golgi	NNP
cord-263699-gosqpg3k	92	32	apparatus	apparatus	NN
cord-263699-gosqpg3k	92	33	.	.	.
cord-263699-gosqpg3k	93	1	Moreover	moreover	RB
cord-263699-gosqpg3k	93	2	,	,	,
cord-263699-gosqpg3k	93	3	it	-PRON-	PRP
cord-263699-gosqpg3k	93	4	has	have	VBZ
cord-263699-gosqpg3k	93	5	also	also	RB
cord-263699-gosqpg3k	93	6	been	be	VBN
cord-263699-gosqpg3k	93	7	observed	observe	VBN
cord-263699-gosqpg3k	93	8	that	that	IN
cord-263699-gosqpg3k	93	9	BFA	BFA	NNP
cord-263699-gosqpg3k	93	10	and	and	CC
cord-263699-gosqpg3k	93	11	GCA	GCA	NNP
cord-263699-gosqpg3k	93	12	induce	induce	VBP
cord-263699-gosqpg3k	93	13	the	the	DT
cord-263699-gosqpg3k	93	14	swelling	swelling	NN
cord-263699-gosqpg3k	93	15	of	of	IN
cord-263699-gosqpg3k	93	16	the	the	DT
cord-263699-gosqpg3k	93	17	ER	ER	NNP
cord-263699-gosqpg3k	93	18	compartment	compartment	NN
cord-263699-gosqpg3k	93	19	,	,	,
cord-263699-gosqpg3k	93	20	likely	likely	RB
cord-263699-gosqpg3k	93	21	due	due	IN
cord-263699-gosqpg3k	93	22	to	to	IN
cord-263699-gosqpg3k	93	23	the	the	DT
cord-263699-gosqpg3k	93	24	fusion	fusion	NN
cord-263699-gosqpg3k	93	25	of	of	IN
cord-263699-gosqpg3k	93	26	the	the	DT
cord-263699-gosqpg3k	93	27	cis	cis	NNP
cord-263699-gosqpg3k	93	28	-	-	HYPH
cord-263699-gosqpg3k	93	29	Golgi	Golgi	NNP
cord-263699-gosqpg3k	93	30	with	with	IN
cord-263699-gosqpg3k	93	31	the	the	DT
cord-263699-gosqpg3k	93	32	ER	er	NN
cord-263699-gosqpg3k	93	33	.	.	.
cord-263699-gosqpg3k	94	1	Both	both	DT
cord-263699-gosqpg3k	94	2	BFA	BFA	NNP
cord-263699-gosqpg3k	94	3	and	and	CC
cord-263699-gosqpg3k	94	4	GCA	GCA	NNP
cord-263699-gosqpg3k	94	5	share	share	VBP
cord-263699-gosqpg3k	94	6	many	many	JJ
cord-263699-gosqpg3k	94	7	similitudes	similitude	NNS
cord-263699-gosqpg3k	94	8	in	in	IN
cord-263699-gosqpg3k	94	9	their	-PRON-	PRP$
cord-263699-gosqpg3k	94	10	effects	effect	NNS
cord-263699-gosqpg3k	94	11	;	;	:
cord-263699-gosqpg3k	94	12	however	however	RB
cord-263699-gosqpg3k	94	13	,	,	,
cord-263699-gosqpg3k	94	14	while	while	IN
cord-263699-gosqpg3k	94	15	BFA	BFA	NNP
cord-263699-gosqpg3k	94	16	has	have	VBZ
cord-263699-gosqpg3k	94	17	been	be	VBN
cord-263699-gosqpg3k	94	18	shown	show	VBN
cord-263699-gosqpg3k	94	19	to	to	TO
cord-263699-gosqpg3k	94	20	inhibit	inhibit	VB
cord-263699-gosqpg3k	94	21	the	the	DT
cord-263699-gosqpg3k	94	22	activity	activity	NN
cord-263699-gosqpg3k	94	23	of	of	IN
cord-263699-gosqpg3k	94	24	GBF1	GBF1	NNP
cord-263699-gosqpg3k	94	25	,	,	,
cord-263699-gosqpg3k	94	26	BIG1	BIG1	NNP
cord-263699-gosqpg3k	94	27	,	,	,
cord-263699-gosqpg3k	94	28	and	and	CC
cord-263699-gosqpg3k	94	29	BIG2	BIG2	NNP
cord-263699-gosqpg3k	94	30	GEFs	gefs	NN
cord-263699-gosqpg3k	94	31	,	,	,
cord-263699-gosqpg3k	94	32	GCA	GCA	NNP
cord-263699-gosqpg3k	94	33	does	do	VBZ
cord-263699-gosqpg3k	94	34	not	not	RB
cord-263699-gosqpg3k	94	35	affect	affect	VB
cord-263699-gosqpg3k	94	36	other	other	JJ
cord-263699-gosqpg3k	94	37	GEFs	gefs	NN
cord-263699-gosqpg3k	94	38	as	as	IN
cord-263699-gosqpg3k	94	39	it	-PRON-	PRP
cord-263699-gosqpg3k	94	40	is	be	VBZ
cord-263699-gosqpg3k	94	41	a	a	DT
cord-263699-gosqpg3k	94	42	specific	specific	JJ
cord-263699-gosqpg3k	94	43	inhibitor	inhibitor	NN
cord-263699-gosqpg3k	94	44	of	of	IN
cord-263699-gosqpg3k	94	45	GBF1	GBF1	NNP
cord-263699-gosqpg3k	94	46	[	[	-LRB-
cord-263699-gosqpg3k	94	47	15	15	CD
cord-263699-gosqpg3k	94	48	,	,	,
cord-263699-gosqpg3k	94	49	32	32	CD
cord-263699-gosqpg3k	94	50	,	,	,
cord-263699-gosqpg3k	94	51	33	33	CD
cord-263699-gosqpg3k	94	52	,	,	,
cord-263699-gosqpg3k	94	53	47	47	CD
cord-263699-gosqpg3k	94	54	]	]	-RRB-
cord-263699-gosqpg3k	94	55	.	.	.
cord-263699-gosqpg3k	95	1	These	these	DT
cord-263699-gosqpg3k	95	2	inhibitors	inhibitor	NNS
cord-263699-gosqpg3k	95	3	have	have	VBP
cord-263699-gosqpg3k	95	4	been	be	VBN
cord-263699-gosqpg3k	95	5	useful	useful	JJ
cord-263699-gosqpg3k	95	6	tools	tool	NNS
cord-263699-gosqpg3k	95	7	for	for	IN
cord-263699-gosqpg3k	95	8	understanding	understand	VBG
cord-263699-gosqpg3k	95	9	the	the	DT
cord-263699-gosqpg3k	95	10	participation	participation	NN
cord-263699-gosqpg3k	95	11	of	of	IN
cord-263699-gosqpg3k	95	12	GBF1	GBF1	NNP
cord-263699-gosqpg3k	95	13	in	in	IN
cord-263699-gosqpg3k	95	14	different	different	JJ
cord-263699-gosqpg3k	95	15	cellular	cellular	JJ
cord-263699-gosqpg3k	95	16	functions	function	NNS
cord-263699-gosqpg3k	95	17	.	.	.
cord-263699-gosqpg3k	96	1	Moreover	moreover	RB
cord-263699-gosqpg3k	96	2	,	,	,
cord-263699-gosqpg3k	96	3	in	in	IN
cord-263699-gosqpg3k	96	4	recent	recent	JJ
cord-263699-gosqpg3k	96	5	years	year	NNS
cord-263699-gosqpg3k	96	6	,	,	,
cord-263699-gosqpg3k	96	7	the	the	DT
cord-263699-gosqpg3k	96	8	use	use	NN
cord-263699-gosqpg3k	96	9	of	of	IN
cord-263699-gosqpg3k	96	10	these	these	DT
cord-263699-gosqpg3k	96	11	drugs	drug	NNS
cord-263699-gosqpg3k	96	12	has	have	VBZ
cord-263699-gosqpg3k	96	13	unveiled	unveil	VBN
cord-263699-gosqpg3k	96	14	the	the	DT
cord-263699-gosqpg3k	96	15	essential	essential	JJ
cord-263699-gosqpg3k	96	16	role	role	NN
cord-263699-gosqpg3k	96	17	that	that	WDT
cord-263699-gosqpg3k	96	18	GBF1	GBF1	NNP
cord-263699-gosqpg3k	96	19	plays	play	VBZ
cord-263699-gosqpg3k	96	20	in	in	IN
cord-263699-gosqpg3k	96	21	the	the	DT
cord-263699-gosqpg3k	96	22	replication	replication	NN
cord-263699-gosqpg3k	96	23	of	of	IN
cord-263699-gosqpg3k	96	24	several	several	JJ
cord-263699-gosqpg3k	96	25	RNA	RNA	NNP
cord-263699-gosqpg3k	96	26	viruses	virus	NNS
cord-263699-gosqpg3k	96	27	that	that	WDT
cord-263699-gosqpg3k	96	28	belong	belong	VBP
cord-263699-gosqpg3k	96	29	to	to	IN
cord-263699-gosqpg3k	96	30	different	different	JJ
cord-263699-gosqpg3k	96	31	families	family	NNS
cord-263699-gosqpg3k	96	32	(	(	-LRB-
cord-263699-gosqpg3k	96	33	Table	table	NN
cord-263699-gosqpg3k	96	34	1	1	CD
cord-263699-gosqpg3k	96	35	)	)	-RRB-
cord-263699-gosqpg3k	96	36	,	,	,
cord-263699-gosqpg3k	96	37	strongly	strongly	RB
cord-263699-gosqpg3k	96	38	suggesting	suggest	VBG
cord-263699-gosqpg3k	96	39	that	that	IN
cord-263699-gosqpg3k	96	40	GBF1	GBF1	NNP
cord-263699-gosqpg3k	96	41	can	can	MD
cord-263699-gosqpg3k	96	42	exhibit	exhibit	VB
cord-263699-gosqpg3k	96	43	diverse	diverse	JJ
cord-263699-gosqpg3k	96	44	functions	function	NNS
cord-263699-gosqpg3k	96	45	that	that	WDT
cord-263699-gosqpg3k	96	46	go	go	VBP
cord-263699-gosqpg3k	96	47	beyond	beyond	IN
cord-263699-gosqpg3k	96	48	its	-PRON-	PRP$
cord-263699-gosqpg3k	96	49	role	role	NN
cord-263699-gosqpg3k	96	50	in	in	IN
cord-263699-gosqpg3k	96	51	vesicle	vesicle	NN
cord-263699-gosqpg3k	96	52	transport	transport	NN
cord-263699-gosqpg3k	96	53	.	.	.
cord-263699-gosqpg3k	97	1	In	in	IN
cord-263699-gosqpg3k	97	2	this	this	DT
cord-263699-gosqpg3k	97	3	review	review	NN
cord-263699-gosqpg3k	97	4	,	,	,
cord-263699-gosqpg3k	97	5	we	-PRON-	PRP
cord-263699-gosqpg3k	97	6	explore	explore	VBP
cord-263699-gosqpg3k	97	7	the	the	DT
cord-263699-gosqpg3k	97	8	current	current	JJ
cord-263699-gosqpg3k	97	9	knowledge	knowledge	NN
cord-263699-gosqpg3k	97	10	of	of	IN
cord-263699-gosqpg3k	97	11	the	the	DT
cord-263699-gosqpg3k	97	12	role	role	NN
cord-263699-gosqpg3k	97	13	GBF1	GBF1	NNP
cord-263699-gosqpg3k	97	14	plays	play	VBZ
cord-263699-gosqpg3k	97	15	in	in	IN
cord-263699-gosqpg3k	97	16	the	the	DT
cord-263699-gosqpg3k	97	17	replication	replication	NN
cord-263699-gosqpg3k	97	18	of	of	IN
cord-263699-gosqpg3k	97	19	RNA	RNA	NNP
cord-263699-gosqpg3k	97	20	viruses	virus	NNS
cord-263699-gosqpg3k	97	21	and	and	CC
cord-263699-gosqpg3k	97	22	present	present	VBP
cord-263699-gosqpg3k	97	23	an	an	DT
cord-263699-gosqpg3k	97	24	overview	overview	NN
cord-263699-gosqpg3k	97	25	of	of	IN
cord-263699-gosqpg3k	97	26	the	the	DT
cord-263699-gosqpg3k	97	27	different	different	JJ
cord-263699-gosqpg3k	97	28	viral	viral	JJ
cord-263699-gosqpg3k	97	29	functions	function	NNS
cord-263699-gosqpg3k	97	30	that	that	WDT
cord-263699-gosqpg3k	97	31	depend	depend	VBP
cord-263699-gosqpg3k	97	32	on	on	IN
cord-263699-gosqpg3k	97	33	the	the	DT
cord-263699-gosqpg3k	97	34	activity	activity	NN
cord-263699-gosqpg3k	97	35	of	of	IN
cord-263699-gosqpg3k	97	36	this	this	DT
cord-263699-gosqpg3k	97	37	factor	factor	NN
cord-263699-gosqpg3k	97	38	.	.	.
cord-263699-gosqpg3k	98	1	Flaviviruses	flavivirus	NNS
cord-263699-gosqpg3k	98	2	are	be	VBP
cord-263699-gosqpg3k	98	3	enveloped	envelop	VBN
cord-263699-gosqpg3k	98	4	,	,	,
cord-263699-gosqpg3k	98	5	positive	positive	JJ
cord-263699-gosqpg3k	98	6	-	-	HYPH
cord-263699-gosqpg3k	98	7	sense	sense	NN
cord-263699-gosqpg3k	98	8	,	,	,
cord-263699-gosqpg3k	98	9	single	single	RB
cord-263699-gosqpg3k	98	10	-	-	HYPH
cord-263699-gosqpg3k	98	11	stranded	strand	VBN
cord-263699-gosqpg3k	98	12	RNA	RNA	NNP
cord-263699-gosqpg3k	98	13	viruses	virus	NNS
cord-263699-gosqpg3k	98	14	with	with	IN
cord-263699-gosqpg3k	98	15	a	a	DT
cord-263699-gosqpg3k	98	16	genome	genome	NN
cord-263699-gosqpg3k	98	17	of	of	IN
cord-263699-gosqpg3k	98	18	approximately	approximately	RB
cord-263699-gosqpg3k	98	19	9.4	9.4	CD
cord-263699-gosqpg3k	98	20	-	-	SYM
cord-263699-gosqpg3k	98	21	13	13	CD
cord-263699-gosqpg3k	98	22	kb	kb	NNS
cord-263699-gosqpg3k	98	23	in	in	IN
cord-263699-gosqpg3k	98	24	length	length	NN
cord-263699-gosqpg3k	98	25	.	.	.
cord-263699-gosqpg3k	99	1	The	the	DT
cord-263699-gosqpg3k	99	2	genome	genome	NN
cord-263699-gosqpg3k	99	3	is	be	VBZ
cord-263699-gosqpg3k	99	4	organized	organize	VBN
cord-263699-gosqpg3k	99	5	as	as	IN
cord-263699-gosqpg3k	99	6	a	a	DT
cord-263699-gosqpg3k	99	7	long	long	JJ
cord-263699-gosqpg3k	99	8	open	open	JJ
cord-263699-gosqpg3k	99	9	reading	reading	NN
cord-263699-gosqpg3k	99	10	frame	frame	NN
cord-263699-gosqpg3k	99	11	(	(	-LRB-
cord-263699-gosqpg3k	99	12	ORF	ORF	NNP
cord-263699-gosqpg3k	99	13	)	)	-RRB-
cord-263699-gosqpg3k	99	14	encoding	encode	VBG
cord-263699-gosqpg3k	99	15	a	a	DT
cord-263699-gosqpg3k	99	16	polyprotein	polyprotein	NN
cord-263699-gosqpg3k	99	17	that	that	WDT
cord-263699-gosqpg3k	99	18	is	be	VBZ
cord-263699-gosqpg3k	99	19	cleaved	cleave	VBN
cord-263699-gosqpg3k	99	20	into	into	IN
cord-263699-gosqpg3k	99	21	three	three	CD
cord-263699-gosqpg3k	99	22	structural	structural	JJ
cord-263699-gosqpg3k	99	23	(	(	-LRB-
cord-263699-gosqpg3k	99	24	C	C	NNP
cord-263699-gosqpg3k	99	25	,	,	,
cord-263699-gosqpg3k	99	26	prM	prm	JJ
cord-263699-gosqpg3k	99	27	,	,	,
cord-263699-gosqpg3k	99	28	and	and	CC
cord-263699-gosqpg3k	99	29	E	E	NNP
cord-263699-gosqpg3k	99	30	)	)	-RRB-
cord-263699-gosqpg3k	99	31	and	and	CC
cord-263699-gosqpg3k	99	32	seven	seven	CD
cord-263699-gosqpg3k	99	33	nonstructural	nonstructural	JJ
cord-263699-gosqpg3k	99	34	(	(	-LRB-
cord-263699-gosqpg3k	99	35	NS1	ns1	UH
cord-263699-gosqpg3k	99	36	,	,	,
cord-263699-gosqpg3k	99	37	NS2A	ns2a	UH
cord-263699-gosqpg3k	99	38	,	,	,
cord-263699-gosqpg3k	99	39	NS2B	NS2B	NNP
cord-263699-gosqpg3k	99	40	,	,	,
cord-263699-gosqpg3k	99	41	NS3	ns3	RB
cord-263699-gosqpg3k	99	42	,	,	,
cord-263699-gosqpg3k	99	43	NS4A	NS4A	NNP
cord-263699-gosqpg3k	99	44	,	,	,
cord-263699-gosqpg3k	99	45	NS4B	NS4B	NNP
cord-263699-gosqpg3k	99	46	,	,	,
cord-263699-gosqpg3k	99	47	and	and	CC
cord-263699-gosqpg3k	99	48	NS5	ns5	JJ
cord-263699-gosqpg3k	99	49	)	)	-RRB-
cord-263699-gosqpg3k	99	50	proteins	protein	NNS
cord-263699-gosqpg3k	99	51	.	.	.
cord-263699-gosqpg3k	100	1	During	during	IN
cord-263699-gosqpg3k	100	2	infection	infection	NN
cord-263699-gosqpg3k	100	3	,	,	,
cord-263699-gosqpg3k	100	4	flaviviruses	flavivirus	NNS
cord-263699-gosqpg3k	100	5	induce	induce	VBP
cord-263699-gosqpg3k	100	6	a	a	DT
cord-263699-gosqpg3k	100	7	profound	profound	JJ
cord-263699-gosqpg3k	100	8	rearrangement	rearrangement	NN
cord-263699-gosqpg3k	100	9	of	of	IN
cord-263699-gosqpg3k	100	10	cellular	cellular	JJ
cord-263699-gosqpg3k	100	11	membranes	membrane	NNS
cord-263699-gosqpg3k	100	12	to	to	TO
cord-263699-gosqpg3k	100	13	provide	provide	VB
cord-263699-gosqpg3k	100	14	platforms	platform	NNS
cord-263699-gosqpg3k	100	15	for	for	IN
cord-263699-gosqpg3k	100	16	viral	viral	JJ
cord-263699-gosqpg3k	100	17	replication	replication	NN
cord-263699-gosqpg3k	100	18	.	.	.
cord-263699-gosqpg3k	101	1	It	-PRON-	PRP
cord-263699-gosqpg3k	101	2	has	have	VBZ
cord-263699-gosqpg3k	101	3	been	be	VBN
cord-263699-gosqpg3k	101	4	observed	observe	VBN
cord-263699-gosqpg3k	101	5	that	that	IN
cord-263699-gosqpg3k	101	6	RNA	RNA	NNP
cord-263699-gosqpg3k	101	7	replication	replication	NN
cord-263699-gosqpg3k	101	8	occurs	occur	VBZ
cord-263699-gosqpg3k	101	9	in	in	IN
cord-263699-gosqpg3k	101	10	vesicular	vesicular	JJ
cord-263699-gosqpg3k	101	11	structures	structure	NNS
cord-263699-gosqpg3k	101	12	called	call	VBD
cord-263699-gosqpg3k	101	13	vesicle	vesicle	NN
cord-263699-gosqpg3k	101	14	packets	packet	NNS
cord-263699-gosqpg3k	101	15	derived	derive	VBN
cord-263699-gosqpg3k	101	16	from	from	IN
cord-263699-gosqpg3k	101	17	membranes	membrane	NNS
cord-263699-gosqpg3k	101	18	of	of	IN
cord-263699-gosqpg3k	101	19	the	the	DT
cord-263699-gosqpg3k	101	20	ER	ER	NNP
cord-263699-gosqpg3k	101	21	[	[	-LRB-
cord-263699-gosqpg3k	101	22	77	77	CD
cord-263699-gosqpg3k	101	23	]	]	-RRB-
cord-263699-gosqpg3k	101	24	.	.	.
cord-263699-gosqpg3k	102	1	Although	although	IN
cord-263699-gosqpg3k	102	2	the	the	DT
cord-263699-gosqpg3k	102	3	assembly	assembly	NN
cord-263699-gosqpg3k	102	4	process	process	NN
cord-263699-gosqpg3k	102	5	of	of	IN
cord-263699-gosqpg3k	102	6	flaviviruses	flavivirus	NNS
cord-263699-gosqpg3k	102	7	is	be	VBZ
cord-263699-gosqpg3k	102	8	unclear	unclear	JJ
cord-263699-gosqpg3k	102	9	,	,	,
cord-263699-gosqpg3k	102	10	it	-PRON-	PRP
cord-263699-gosqpg3k	102	11	has	have	VBZ
cord-263699-gosqpg3k	102	12	been	be	VBN
cord-263699-gosqpg3k	102	13	suggested	suggest	VBN
cord-263699-gosqpg3k	102	14	that	that	IN
cord-263699-gosqpg3k	102	15	during	during	IN
cord-263699-gosqpg3k	102	16	RNA	RNA	NNP
cord-263699-gosqpg3k	102	17	replication	replication	NN
cord-263699-gosqpg3k	102	18	,	,	,
cord-263699-gosqpg3k	102	19	the	the	DT
cord-263699-gosqpg3k	102	20	viral	viral	JJ
cord-263699-gosqpg3k	102	21	capsid	capsid	NN
cord-263699-gosqpg3k	102	22	protein	protein	NN
cord-263699-gosqpg3k	102	23	(	(	-LRB-
cord-263699-gosqpg3k	102	24	C	C	NNP
cord-263699-gosqpg3k	102	25	protein	protein	NN
cord-263699-gosqpg3k	102	26	)	)	-RRB-
cord-263699-gosqpg3k	102	27	,	,	,
cord-263699-gosqpg3k	102	28	located	locate	VBN
cord-263699-gosqpg3k	102	29	on	on	IN
cord-263699-gosqpg3k	102	30	the	the	DT
cord-263699-gosqpg3k	102	31	surface	surface	NN
cord-263699-gosqpg3k	102	32	of	of	IN
cord-263699-gosqpg3k	102	33	LDs	LDs	NNP
cord-263699-gosqpg3k	102	34	,	,	,
cord-263699-gosqpg3k	102	35	recruits	recruit	VBZ
cord-263699-gosqpg3k	102	36	the	the	DT
cord-263699-gosqpg3k	102	37	viral	viral	JJ
cord-263699-gosqpg3k	102	38	genome	genome	NN
cord-263699-gosqpg3k	102	39	for	for	IN
cord-263699-gosqpg3k	102	40	formation	formation	NN
cord-263699-gosqpg3k	102	41	of	of	IN
cord-263699-gosqpg3k	102	42	the	the	DT
cord-263699-gosqpg3k	102	43	nucleocapsid	nucleocapsid	NN
cord-263699-gosqpg3k	102	44	[	[	-LRB-
cord-263699-gosqpg3k	102	45	78	78	CD
cord-263699-gosqpg3k	102	46	]	]	-RRB-
cord-263699-gosqpg3k	102	47	.	.	.
cord-263699-gosqpg3k	103	1	The	the	DT
cord-263699-gosqpg3k	103	2	newly	newly	RB
cord-263699-gosqpg3k	103	3	formed	form	VBN
cord-263699-gosqpg3k	103	4	nucleocapsid	nucleocapsid	NN
cord-263699-gosqpg3k	103	5	then	then	RB
cord-263699-gosqpg3k	103	6	buds	bud	NNS
cord-263699-gosqpg3k	103	7	into	into	IN
cord-263699-gosqpg3k	103	8	the	the	DT
cord-263699-gosqpg3k	103	9	ER	ER	NNP
cord-263699-gosqpg3k	103	10	lumen	lumen	NN
cord-263699-gosqpg3k	103	11	,	,	,
cord-263699-gosqpg3k	103	12	acquiring	acquire	VBG
cord-263699-gosqpg3k	103	13	during	during	IN
cord-263699-gosqpg3k	103	14	this	this	DT
cord-263699-gosqpg3k	103	15	process	process	NN
cord-263699-gosqpg3k	103	16	the	the	DT
cord-263699-gosqpg3k	103	17	structural	structural	JJ
cord-263699-gosqpg3k	103	18	glycoproteins	glycoprotein	NNS
cord-263699-gosqpg3k	103	19	E	e	NN
cord-263699-gosqpg3k	103	20	and	and	CC
cord-263699-gosqpg3k	103	21	prM	prm	JJ
cord-263699-gosqpg3k	103	22	,	,	,
cord-263699-gosqpg3k	103	23	as	as	RB
cord-263699-gosqpg3k	103	24	well	well	RB
cord-263699-gosqpg3k	103	25	as	as	IN
cord-263699-gosqpg3k	103	26	the	the	DT
cord-263699-gosqpg3k	103	27	membrane	membrane	NN
cord-263699-gosqpg3k	103	28	envelope	envelope	NN
cord-263699-gosqpg3k	103	29	.	.	.
cord-263699-gosqpg3k	104	1	Finally	finally	RB
cord-263699-gosqpg3k	104	2	,	,	,
cord-263699-gosqpg3k	104	3	as	as	IN
cord-263699-gosqpg3k	104	4	the	the	DT
cord-263699-gosqpg3k	104	5	novel	novel	JJ
cord-263699-gosqpg3k	104	6	viral	viral	JJ
cord-263699-gosqpg3k	104	7	particle	particle	NN
cord-263699-gosqpg3k	104	8	travels	travel	VBZ
cord-263699-gosqpg3k	104	9	through	through	IN
cord-263699-gosqpg3k	104	10	the	the	DT
cord-263699-gosqpg3k	104	11	secretory	secretory	JJ
cord-263699-gosqpg3k	104	12	pathway	pathway	NN
cord-263699-gosqpg3k	104	13	to	to	TO
cord-263699-gosqpg3k	104	14	be	be	VB
cord-263699-gosqpg3k	104	15	released	release	VBN
cord-263699-gosqpg3k	104	16	by	by	IN
cord-263699-gosqpg3k	104	17	exocytosis	exocytosis	NN
cord-263699-gosqpg3k	104	18	,	,	,
cord-263699-gosqpg3k	104	19	the	the	DT
cord-263699-gosqpg3k	104	20	virus	virus	NN
cord-263699-gosqpg3k	104	21	experiments	experiment	VBZ
cord-263699-gosqpg3k	104	22	a	a	DT
cord-263699-gosqpg3k	104	23	maturation	maturation	NN
cord-263699-gosqpg3k	104	24	process	process	NN
cord-263699-gosqpg3k	104	25	in	in	IN
cord-263699-gosqpg3k	104	26	which	which	WDT
cord-263699-gosqpg3k	104	27	the	the	DT
cord-263699-gosqpg3k	104	28	prM	prm	JJ
cord-263699-gosqpg3k	104	29	protein	protein	NN
cord-263699-gosqpg3k	104	30	is	be	VBZ
cord-263699-gosqpg3k	104	31	cleaved	cleave	VBN
cord-263699-gosqpg3k	104	32	by	by	IN
cord-263699-gosqpg3k	104	33	the	the	DT
cord-263699-gosqpg3k	104	34	furin	furin	NN
cord-263699-gosqpg3k	104	35	protease	protease	NN
cord-263699-gosqpg3k	104	36	to	to	TO
cord-263699-gosqpg3k	104	37	yield	yield	VB
cord-263699-gosqpg3k	104	38	the	the	DT
cord-263699-gosqpg3k	104	39	mature	mature	JJ
cord-263699-gosqpg3k	104	40	M	M	NNP
cord-263699-gosqpg3k	104	41	protein	protein	NN
cord-263699-gosqpg3k	104	42	[	[	-LRB-
cord-263699-gosqpg3k	104	43	77	77	CD
cord-263699-gosqpg3k	104	44	]	]	-RRB-
cord-263699-gosqpg3k	104	45	.	.	.
cord-263699-gosqpg3k	105	1	In	in	IN
cord-263699-gosqpg3k	105	2	recent	recent	JJ
cord-263699-gosqpg3k	105	3	years	year	NNS
cord-263699-gosqpg3k	105	4	,	,	,
cord-263699-gosqpg3k	105	5	increasing	increase	VBG
cord-263699-gosqpg3k	105	6	evidences	evidence	NNS
cord-263699-gosqpg3k	105	7	have	have	VBP
cord-263699-gosqpg3k	105	8	shown	show	VBN
cord-263699-gosqpg3k	105	9	that	that	IN
cord-263699-gosqpg3k	105	10	GBF1	GBF1	NNP
cord-263699-gosqpg3k	105	11	is	be	VBZ
cord-263699-gosqpg3k	105	12	an	an	DT
cord-263699-gosqpg3k	105	13	important	important	JJ
cord-263699-gosqpg3k	105	14	cellular	cellular	JJ
cord-263699-gosqpg3k	105	15	factor	factor	NN
cord-263699-gosqpg3k	105	16	involved	involve	VBN
cord-263699-gosqpg3k	105	17	in	in	IN
cord-263699-gosqpg3k	105	18	the	the	DT
cord-263699-gosqpg3k	105	19	replication	replication	NN
cord-263699-gosqpg3k	105	20	of	of	IN
cord-263699-gosqpg3k	105	21	several	several	JJ
cord-263699-gosqpg3k	105	22	flaviviruses	flavivirus	NNS
cord-263699-gosqpg3k	105	23	,	,	,
cord-263699-gosqpg3k	105	24	including	include	VBG
cord-263699-gosqpg3k	105	25	dengue	dengue	NN
cord-263699-gosqpg3k	105	26	virus	virus	NN
cord-263699-gosqpg3k	105	27	(	(	-LRB-
cord-263699-gosqpg3k	105	28	DENV	DENV	NNP
cord-263699-gosqpg3k	105	29	)	)	-RRB-
cord-263699-gosqpg3k	105	30	[	[	-LRB-
cord-263699-gosqpg3k	105	31	49	49	CD
cord-263699-gosqpg3k	105	32	,	,	,
cord-263699-gosqpg3k	105	33	[	[	-LRB-
cord-263699-gosqpg3k	105	34	78	78	CD
cord-263699-gosqpg3k	105	35	]	]	-RRB-
cord-263699-gosqpg3k	105	36	[	[	-LRB-
cord-263699-gosqpg3k	105	37	79	79	CD
cord-263699-gosqpg3k	105	38	]	]	-RRB-
cord-263699-gosqpg3k	105	39	[	[	-LRB-
cord-263699-gosqpg3k	105	40	80	80	CD
cord-263699-gosqpg3k	105	41	]	]	-RRB-
cord-263699-gosqpg3k	105	42	,	,	,
cord-263699-gosqpg3k	105	43	yellow	yellow	JJ
cord-263699-gosqpg3k	105	44	fever	fever	NN
cord-263699-gosqpg3k	105	45	virus	virus	NN
cord-263699-gosqpg3k	105	46	(	(	-LRB-
cord-263699-gosqpg3k	105	47	YFV	YFV	NNP
cord-263699-gosqpg3k	105	48	)	)	-RRB-
cord-263699-gosqpg3k	105	49	[	[	-LRB-
cord-263699-gosqpg3k	105	50	51	51	CD
cord-263699-gosqpg3k	105	51	]	]	-RRB-
cord-263699-gosqpg3k	105	52	,	,	,
cord-263699-gosqpg3k	105	53	tick	tick	VB
cord-263699-gosqpg3k	105	54	-	-	HYPH
cord-263699-gosqpg3k	105	55	borne	bear	VBN
cord-263699-gosqpg3k	105	56	encephalitis	encephalitis	JJ
cord-263699-gosqpg3k	105	57	virus	virus	NN
cord-263699-gosqpg3k	105	58	(	(	-LRB-
cord-263699-gosqpg3k	105	59	TBEV	TBEV	NNP
cord-263699-gosqpg3k	105	60	)	)	-RRB-
cord-263699-gosqpg3k	105	61	[	[	-LRB-
cord-263699-gosqpg3k	105	62	50	50	CD
cord-263699-gosqpg3k	105	63	]	]	-RRB-
cord-263699-gosqpg3k	105	64	,	,	,
cord-263699-gosqpg3k	105	65	and	and	CC
cord-263699-gosqpg3k	105	66	Kunjin	Kunjin	NNP
cord-263699-gosqpg3k	105	67	virus	virus	NN
cord-263699-gosqpg3k	105	68	(	(	-LRB-
cord-263699-gosqpg3k	105	69	KUN	KUN	NNP
cord-263699-gosqpg3k	105	70	)	)	-RRB-
cord-263699-gosqpg3k	105	71	[	[	-LRB-
cord-263699-gosqpg3k	105	72	52	52	CD
cord-263699-gosqpg3k	105	73	]	]	-RRB-
cord-263699-gosqpg3k	105	74	.	.	.
cord-263699-gosqpg3k	106	1	In	in	IN
cord-263699-gosqpg3k	106	2	the	the	DT
cord-263699-gosqpg3k	106	3	case	case	NN
cord-263699-gosqpg3k	106	4	of	of	IN
cord-263699-gosqpg3k	106	5	DENV	DENV	NNP
cord-263699-gosqpg3k	106	6	,	,	,
cord-263699-gosqpg3k	106	7	it	-PRON-	PRP
cord-263699-gosqpg3k	106	8	was	be	VBD
cord-263699-gosqpg3k	106	9	shown	show	VBN
cord-263699-gosqpg3k	106	10	that	that	IN
cord-263699-gosqpg3k	106	11	BFA	BFA	NNP
cord-263699-gosqpg3k	106	12	and	and	CC
cord-263699-gosqpg3k	106	13	GCA	GCA	NNP
cord-263699-gosqpg3k	106	14	reduce	reduce	VB
cord-263699-gosqpg3k	106	15	the	the	DT
cord-263699-gosqpg3k	106	16	abundance	abundance	NN
cord-263699-gosqpg3k	106	17	of	of	IN
cord-263699-gosqpg3k	106	18	viral	viral	JJ
cord-263699-gosqpg3k	106	19	RNA	RNA	NNP
cord-263699-gosqpg3k	106	20	,	,	,
cord-263699-gosqpg3k	106	21	and	and	CC
cord-263699-gosqpg3k	106	22	depletion	depletion	NN
cord-263699-gosqpg3k	106	23	of	of	IN
cord-263699-gosqpg3k	106	24	GBF1	GBF1	NNP
cord-263699-gosqpg3k	106	25	was	be	VBD
cord-263699-gosqpg3k	106	26	sufficient	sufficient	JJ
cord-263699-gosqpg3k	106	27	to	to	TO
cord-263699-gosqpg3k	106	28	cause	cause	VB
cord-263699-gosqpg3k	106	29	this	this	DT
cord-263699-gosqpg3k	106	30	reduction	reduction	NN
cord-263699-gosqpg3k	106	31	and	and	CC
cord-263699-gosqpg3k	106	32	to	to	TO
cord-263699-gosqpg3k	106	33	inhibit	inhibit	VB
cord-263699-gosqpg3k	106	34	the	the	DT
cord-263699-gosqpg3k	106	35	viral	viral	JJ
cord-263699-gosqpg3k	106	36	production	production	NN
cord-263699-gosqpg3k	106	37	[	[	-LRB-
cord-263699-gosqpg3k	106	38	49	49	CD
cord-263699-gosqpg3k	106	39	,	,	,
cord-263699-gosqpg3k	106	40	79	79	CD
cord-263699-gosqpg3k	106	41	]	]	-RRB-
cord-263699-gosqpg3k	106	42	.	.	.
cord-263699-gosqpg3k	107	1	Also	also	RB
cord-263699-gosqpg3k	107	2	,	,	,
cord-263699-gosqpg3k	107	3	BFA	BFA	NNP
cord-263699-gosqpg3k	107	4	has	have	VBZ
cord-263699-gosqpg3k	107	5	been	be	VBN
cord-263699-gosqpg3k	107	6	shown	show	VBN
cord-263699-gosqpg3k	107	7	to	to	TO
cord-263699-gosqpg3k	107	8	retard	retard	VB
cord-263699-gosqpg3k	107	9	the	the	DT
cord-263699-gosqpg3k	107	10	mortality	mortality	NN
cord-263699-gosqpg3k	107	11	of	of	IN
cord-263699-gosqpg3k	107	12	mice	mouse	NNS
cord-263699-gosqpg3k	107	13	infected	infect	VBN
cord-263699-gosqpg3k	107	14	with	with	IN
cord-263699-gosqpg3k	107	15	DENV	DENV	NNP
cord-263699-gosqpg3k	107	16	,	,	,
cord-263699-gosqpg3k	107	17	but	but	CC
cord-263699-gosqpg3k	107	18	not	not	RB
cord-263699-gosqpg3k	107	19	to	to	TO
cord-263699-gosqpg3k	107	20	alter	alter	VB
cord-263699-gosqpg3k	107	21	the	the	DT
cord-263699-gosqpg3k	107	22	final	final	JJ
cord-263699-gosqpg3k	107	23	mortality	mortality	NN
cord-263699-gosqpg3k	107	24	outcome	outcome	NN
cord-263699-gosqpg3k	107	25	[	[	-LRB-
cord-263699-gosqpg3k	107	26	81	81	CD
cord-263699-gosqpg3k	107	27	]	]	-RRB-
cord-263699-gosqpg3k	107	28	.	.	.
cord-263699-gosqpg3k	108	1	In	in	IN
cord-263699-gosqpg3k	108	2	support	support	NN
cord-263699-gosqpg3k	108	3	of	of	IN
cord-263699-gosqpg3k	108	4	the	the	DT
cord-263699-gosqpg3k	108	5	participation	participation	NN
cord-263699-gosqpg3k	108	6	of	of	IN
cord-263699-gosqpg3k	108	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	108	8	in	in	IN
cord-263699-gosqpg3k	108	9	the	the	DT
cord-263699-gosqpg3k	108	10	DENV	DENV	NNP
cord-263699-gosqpg3k	108	11	lifecycle	lifecycle	NN
cord-263699-gosqpg3k	108	12	,	,	,
cord-263699-gosqpg3k	108	13	it	-PRON-	PRP
cord-263699-gosqpg3k	108	14	was	be	VBD
cord-263699-gosqpg3k	108	15	found	find	VBN
cord-263699-gosqpg3k	108	16	that	that	IN
cord-263699-gosqpg3k	108	17	the	the	DT
cord-263699-gosqpg3k	108	18	viral	viral	JJ
cord-263699-gosqpg3k	108	19	RNA	RNA	NNP
cord-263699-gosqpg3k	108	20	decrease	decrease	NN
cord-263699-gosqpg3k	108	21	induced	induce	VBN
cord-263699-gosqpg3k	108	22	by	by	IN
cord-263699-gosqpg3k	108	23	GCA	GCA	NNP
cord-263699-gosqpg3k	108	24	could	could	MD
cord-263699-gosqpg3k	108	25	be	be	VB
cord-263699-gosqpg3k	108	26	reverted	revert	VBN
cord-263699-gosqpg3k	108	27	by	by	IN
cord-263699-gosqpg3k	108	28	overexpression	overexpression	NN
cord-263699-gosqpg3k	108	29	of	of	IN
cord-263699-gosqpg3k	108	30	either	either	DT
cord-263699-gosqpg3k	108	31	wild	wild	JJ
cord-263699-gosqpg3k	108	32	-	-	HYPH
cord-263699-gosqpg3k	108	33	type	type	NN
cord-263699-gosqpg3k	108	34	GBF1	GBF1	NNP
cord-263699-gosqpg3k	108	35	(	(	-LRB-
cord-263699-gosqpg3k	108	36	GBF1-Wt	GBF1-Wt	NNP
cord-263699-gosqpg3k	108	37	)	)	-RRB-
cord-263699-gosqpg3k	108	38	or	or	CC
cord-263699-gosqpg3k	108	39	a	a	DT
cord-263699-gosqpg3k	108	40	drug	drug	NN
cord-263699-gosqpg3k	108	41	resistant	resistant	JJ
cord-263699-gosqpg3k	108	42	GBF1	GBF1	NNP
cord-263699-gosqpg3k	108	43	mutant	mutant	NN
cord-263699-gosqpg3k	108	44	[	[	-LRB-
cord-263699-gosqpg3k	108	45	47	47	CD
cord-263699-gosqpg3k	108	46	,	,	,
cord-263699-gosqpg3k	108	47	79	79	CD
cord-263699-gosqpg3k	108	48	]	]	-RRB-
cord-263699-gosqpg3k	108	49	.	.	.
cord-263699-gosqpg3k	109	1	The	the	DT
cord-263699-gosqpg3k	109	2	mechanism	mechanism	NN
cord-263699-gosqpg3k	109	3	through	through	IN
cord-263699-gosqpg3k	109	4	which	which	WDT
cord-263699-gosqpg3k	109	5	GBF1	GBF1	NNP
cord-263699-gosqpg3k	109	6	favors	favor	VBZ
cord-263699-gosqpg3k	109	7	the	the	DT
cord-263699-gosqpg3k	109	8	replication	replication	NN
cord-263699-gosqpg3k	109	9	of	of	IN
cord-263699-gosqpg3k	109	10	DENV	DENV	NNP
cord-263699-gosqpg3k	109	11	RNA	RNA	NNP
cord-263699-gosqpg3k	109	12	is	be	VBZ
cord-263699-gosqpg3k	109	13	unknown	unknown	JJ
cord-263699-gosqpg3k	109	14	;	;	:
cord-263699-gosqpg3k	109	15	however	however	RB
cord-263699-gosqpg3k	109	16	,	,	,
cord-263699-gosqpg3k	109	17	the	the	DT
cord-263699-gosqpg3k	109	18	fact	fact	NN
cord-263699-gosqpg3k	109	19	that	that	IN
cord-263699-gosqpg3k	109	20	this	this	DT
cord-263699-gosqpg3k	109	21	factor	factor	NN
cord-263699-gosqpg3k	109	22	directly	directly	RB
cord-263699-gosqpg3k	109	23	interacts	interact	VBZ
cord-263699-gosqpg3k	109	24	with	with	IN
cord-263699-gosqpg3k	109	25	the	the	DT
cord-263699-gosqpg3k	109	26	NS5	ns5	JJ
cord-263699-gosqpg3k	109	27	protein	protein	NN
cord-263699-gosqpg3k	109	28	,	,	,
cord-263699-gosqpg3k	109	29	the	the	DT
cord-263699-gosqpg3k	109	30	viral	viral	JJ
cord-263699-gosqpg3k	109	31	RNA	RNA	NNP
cord-263699-gosqpg3k	109	32	-	-	HYPH
cord-263699-gosqpg3k	109	33	dependent	dependent	JJ
cord-263699-gosqpg3k	109	34	RNA	RNA	NNP
cord-263699-gosqpg3k	109	35	polymerase	polymerase	NN
cord-263699-gosqpg3k	109	36	(	(	-LRB-
cord-263699-gosqpg3k	109	37	RdRp	RdRp	NNP
cord-263699-gosqpg3k	109	38	)	)	-RRB-
cord-263699-gosqpg3k	109	39	of	of	IN
cord-263699-gosqpg3k	109	40	DENV	DENV	NNP
cord-263699-gosqpg3k	109	41	,	,	,
cord-263699-gosqpg3k	109	42	suggests	suggest	VBZ
cord-263699-gosqpg3k	109	43	that	that	IN
cord-263699-gosqpg3k	109	44	GBF1	GBF1	NNP
cord-263699-gosqpg3k	109	45	might	may	MD
cord-263699-gosqpg3k	109	46	be	be	VB
cord-263699-gosqpg3k	109	47	directly	directly	RB
cord-263699-gosqpg3k	109	48	involved	involve	VBN
cord-263699-gosqpg3k	109	49	in	in	IN
cord-263699-gosqpg3k	109	50	the	the	DT
cord-263699-gosqpg3k	109	51	RNA	RNA	NNP
cord-263699-gosqpg3k	109	52	replication	replication	NN
cord-263699-gosqpg3k	109	53	process	process	NN
cord-263699-gosqpg3k	109	54	through	through	IN
cord-263699-gosqpg3k	109	55	regulation	regulation	NN
cord-263699-gosqpg3k	109	56	of	of	IN
cord-263699-gosqpg3k	109	57	the	the	DT
cord-263699-gosqpg3k	109	58	activity	activity	NN
cord-263699-gosqpg3k	109	59	of	of	IN
cord-263699-gosqpg3k	109	60	NS5	ns5	JJ
cord-263699-gosqpg3k	109	61	[	[	-LRB-
cord-263699-gosqpg3k	109	62	79	79	CD
cord-263699-gosqpg3k	109	63	]	]	-RRB-
cord-263699-gosqpg3k	109	64	;	;	:
cord-263699-gosqpg3k	109	65	alternatively	alternatively	RB
cord-263699-gosqpg3k	109	66	,	,	,
cord-263699-gosqpg3k	109	67	it	-PRON-	PRP
cord-263699-gosqpg3k	109	68	has	have	VBZ
cord-263699-gosqpg3k	109	69	also	also	RB
cord-263699-gosqpg3k	109	70	been	be	VBN
cord-263699-gosqpg3k	109	71	proposed	propose	VBN
cord-263699-gosqpg3k	109	72	that	that	IN
cord-263699-gosqpg3k	109	73	GBF1	GBF1	NNP
cord-263699-gosqpg3k	109	74	might	may	MD
cord-263699-gosqpg3k	109	75	modulate	modulate	VB
cord-263699-gosqpg3k	109	76	the	the	DT
cord-263699-gosqpg3k	109	77	replication	replication	NN
cord-263699-gosqpg3k	109	78	of	of	IN
cord-263699-gosqpg3k	109	79	viral	viral	JJ
cord-263699-gosqpg3k	109	80	RNA	RNA	NNP
cord-263699-gosqpg3k	109	81	by	by	IN
cord-263699-gosqpg3k	109	82	participating	participate	VBG
cord-263699-gosqpg3k	109	83	in	in	IN
cord-263699-gosqpg3k	109	84	the	the	DT
cord-263699-gosqpg3k	109	85	biogenesis	biogenesis	NN
cord-263699-gosqpg3k	109	86	of	of	IN
cord-263699-gosqpg3k	109	87	the	the	DT
cord-263699-gosqpg3k	109	88	viral	viral	JJ
cord-263699-gosqpg3k	109	89	vesicle	vesicle	NN
cord-263699-gosqpg3k	109	90	packets	packet	NNS
cord-263699-gosqpg3k	109	91	[	[	-LRB-
cord-263699-gosqpg3k	109	92	79	79	CD
cord-263699-gosqpg3k	109	93	]	]	-RRB-
cord-263699-gosqpg3k	109	94	.	.	.
cord-263699-gosqpg3k	110	1	In	in	IN
cord-263699-gosqpg3k	110	2	support	support	NN
cord-263699-gosqpg3k	110	3	of	of	IN
cord-263699-gosqpg3k	110	4	this	this	DT
cord-263699-gosqpg3k	110	5	latter	latter	JJ
cord-263699-gosqpg3k	110	6	idea	idea	NN
cord-263699-gosqpg3k	110	7	,	,	,
cord-263699-gosqpg3k	110	8	it	-PRON-	PRP
cord-263699-gosqpg3k	110	9	has	have	VBZ
cord-263699-gosqpg3k	110	10	been	be	VBN
cord-263699-gosqpg3k	110	11	reported	report	VBN
cord-263699-gosqpg3k	110	12	that	that	IN
cord-263699-gosqpg3k	110	13	BFA	BFA	NNP
cord-263699-gosqpg3k	110	14	can	can	MD
cord-263699-gosqpg3k	110	15	prevent	prevent	VB
cord-263699-gosqpg3k	110	16	the	the	DT
cord-263699-gosqpg3k	110	17	membrane	membrane	NN
cord-263699-gosqpg3k	110	18	rearrangement	rearrangement	NN
cord-263699-gosqpg3k	110	19	induced	induce	VBN
cord-263699-gosqpg3k	110	20	by	by	IN
cord-263699-gosqpg3k	110	21	KUN	KUN	NNP
cord-263699-gosqpg3k	110	22	,	,	,
cord-263699-gosqpg3k	110	23	when	when	WRB
cord-263699-gosqpg3k	110	24	the	the	DT
cord-263699-gosqpg3k	110	25	drug	drug	NN
cord-263699-gosqpg3k	110	26	is	be	VBZ
cord-263699-gosqpg3k	110	27	added	add	VBN
cord-263699-gosqpg3k	110	28	at	at	IN
cord-263699-gosqpg3k	110	29	early	early	JJ
cord-263699-gosqpg3k	110	30	times	time	NNS
cord-263699-gosqpg3k	110	31	of	of	IN
cord-263699-gosqpg3k	110	32	infection	infection	NN
cord-263699-gosqpg3k	110	33	[	[	-LRB-
cord-263699-gosqpg3k	110	34	52	52	CD
cord-263699-gosqpg3k	110	35	]	]	-RRB-
cord-263699-gosqpg3k	110	36	.	.	.
cord-263699-gosqpg3k	111	1	Altogether	altogether	RB
cord-263699-gosqpg3k	111	2	,	,	,
cord-263699-gosqpg3k	111	3	these	these	DT
cord-263699-gosqpg3k	111	4	findings	finding	NNS
cord-263699-gosqpg3k	111	5	suggest	suggest	VBP
cord-263699-gosqpg3k	111	6	that	that	IN
cord-263699-gosqpg3k	111	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	111	8	might	may	MD
cord-263699-gosqpg3k	111	9	engage	engage	VB
cord-263699-gosqpg3k	111	10	the	the	DT
cord-263699-gosqpg3k	111	11	nascent	nascent	JJ
cord-263699-gosqpg3k	111	12	replication	replication	NN
cord-263699-gosqpg3k	111	13	complexes	complex	NNS
cord-263699-gosqpg3k	111	14	of	of	IN
cord-263699-gosqpg3k	111	15	flavivirus	flavivirus	NNP
cord-263699-gosqpg3k	111	16	(	(	-LRB-
cord-263699-gosqpg3k	111	17	vesicle	vesicle	NN
cord-263699-gosqpg3k	111	18	packets	packet	VBZ
cord-263699-gosqpg3k	111	19	)	)	-RRB-
cord-263699-gosqpg3k	111	20	through	through	IN
cord-263699-gosqpg3k	111	21	its	-PRON-	PRP$
cord-263699-gosqpg3k	111	22	interaction	interaction	NN
cord-263699-gosqpg3k	111	23	with	with	IN
cord-263699-gosqpg3k	111	24	NS5	NS5	NNP
cord-263699-gosqpg3k	111	25	;	;	:
cord-263699-gosqpg3k	111	26	once	once	RB
cord-263699-gosqpg3k	111	27	in	in	IN
cord-263699-gosqpg3k	111	28	these	these	DT
cord-263699-gosqpg3k	111	29	sites	site	NNS
cord-263699-gosqpg3k	111	30	,	,	,
cord-263699-gosqpg3k	111	31	GBF1	GBF1	NNP
cord-263699-gosqpg3k	111	32	could	could	MD
cord-263699-gosqpg3k	111	33	regulate	regulate	VB
cord-263699-gosqpg3k	111	34	the	the	DT
cord-263699-gosqpg3k	111	35	formation	formation	NN
cord-263699-gosqpg3k	111	36	of	of	IN
cord-263699-gosqpg3k	111	37	these	these	DT
cord-263699-gosqpg3k	111	38	viral	viral	JJ
cord-263699-gosqpg3k	111	39	organelles	organelle	NNS
cord-263699-gosqpg3k	111	40	through	through	IN
cord-263699-gosqpg3k	111	41	the	the	DT
cord-263699-gosqpg3k	111	42	activation	activation	NN
cord-263699-gosqpg3k	111	43	of	of	IN
cord-263699-gosqpg3k	111	44	Arf	Arf	NNP
cord-263699-gosqpg3k	111	45	proteins	protein	NNS
cord-263699-gosqpg3k	111	46	and	and	CC
cord-263699-gosqpg3k	111	47	the	the	DT
cord-263699-gosqpg3k	111	48	recruitment	recruitment	NN
cord-263699-gosqpg3k	111	49	of	of	IN
cord-263699-gosqpg3k	111	50	cellular	cellular	JJ
cord-263699-gosqpg3k	111	51	effectors	effector	NNS
cord-263699-gosqpg3k	111	52	that	that	WDT
cord-263699-gosqpg3k	111	53	ultimately	ultimately	RB
cord-263699-gosqpg3k	111	54	could	could	MD
cord-263699-gosqpg3k	111	55	lead	lead	VB
cord-263699-gosqpg3k	111	56	to	to	IN
cord-263699-gosqpg3k	111	57	the	the	DT
cord-263699-gosqpg3k	111	58	creation	creation	NN
cord-263699-gosqpg3k	111	59	of	of	IN
cord-263699-gosqpg3k	111	60	a	a	DT
cord-263699-gosqpg3k	111	61	microenvironment	microenvironment	NN
cord-263699-gosqpg3k	111	62	that	that	WDT
cord-263699-gosqpg3k	111	63	allows	allow	VBZ
cord-263699-gosqpg3k	111	64	the	the	DT
cord-263699-gosqpg3k	111	65	proper	proper	JJ
cord-263699-gosqpg3k	111	66	activity	activity	NN
cord-263699-gosqpg3k	111	67	of	of	IN
cord-263699-gosqpg3k	111	68	NS5	NS5	NNP
cord-263699-gosqpg3k	111	69	.	.	.
cord-263699-gosqpg3k	112	1	In	in	IN
cord-263699-gosqpg3k	112	2	addition	addition	NN
cord-263699-gosqpg3k	112	3	to	to	IN
cord-263699-gosqpg3k	112	4	the	the	DT
cord-263699-gosqpg3k	112	5	role	role	NN
cord-263699-gosqpg3k	112	6	of	of	IN
cord-263699-gosqpg3k	112	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	112	8	in	in	IN
cord-263699-gosqpg3k	112	9	RNA	RNA	NNP
cord-263699-gosqpg3k	112	10	replication	replication	NN
cord-263699-gosqpg3k	112	11	,	,	,
cord-263699-gosqpg3k	112	12	it	-PRON-	PRP
cord-263699-gosqpg3k	112	13	has	have	VBZ
cord-263699-gosqpg3k	112	14	been	be	VBN
cord-263699-gosqpg3k	112	15	reported	report	VBN
cord-263699-gosqpg3k	112	16	that	that	IN
cord-263699-gosqpg3k	112	17	depletion	depletion	NN
cord-263699-gosqpg3k	112	18	of	of	IN
cord-263699-gosqpg3k	112	19	this	this	DT
cord-263699-gosqpg3k	112	20	factor	factor	NN
cord-263699-gosqpg3k	112	21	or	or	CC
cord-263699-gosqpg3k	112	22	its	-PRON-	PRP$
cord-263699-gosqpg3k	112	23	pharmacological	pharmacological	JJ
cord-263699-gosqpg3k	112	24	inhibition	inhibition	NN
cord-263699-gosqpg3k	112	25	with	with	IN
cord-263699-gosqpg3k	112	26	BFA	BFA	NNP
cord-263699-gosqpg3k	112	27	could	could	MD
cord-263699-gosqpg3k	112	28	also	also	RB
cord-263699-gosqpg3k	112	29	affect	affect	VB
cord-263699-gosqpg3k	112	30	the	the	DT
cord-263699-gosqpg3k	112	31	DENV	DENV	NNP
cord-263699-gosqpg3k	112	32	assembly	assembly	NN
cord-263699-gosqpg3k	112	33	by	by	IN
cord-263699-gosqpg3k	112	34	blocking	block	VBG
cord-263699-gosqpg3k	112	35	the	the	DT
cord-263699-gosqpg3k	112	36	accumulation	accumulation	NN
cord-263699-gosqpg3k	112	37	of	of	IN
cord-263699-gosqpg3k	112	38	the	the	DT
cord-263699-gosqpg3k	112	39	C	C	NNP
cord-263699-gosqpg3k	112	40	protein	protein	NN
cord-263699-gosqpg3k	112	41	into	into	IN
cord-263699-gosqpg3k	112	42	the	the	DT
cord-263699-gosqpg3k	112	43	LDs	LDs	NNP
cord-263699-gosqpg3k	112	44	,	,	,
cord-263699-gosqpg3k	112	45	which	which	WDT
cord-263699-gosqpg3k	112	46	depends	depend	VBZ
cord-263699-gosqpg3k	112	47	on	on	IN
cord-263699-gosqpg3k	112	48	the	the	DT
cord-263699-gosqpg3k	112	49	catalytic	catalytic	JJ
cord-263699-gosqpg3k	112	50	activity	activity	NN
cord-263699-gosqpg3k	112	51	of	of	IN
cord-263699-gosqpg3k	112	52	GBF1	GBF1	NNP
cord-263699-gosqpg3k	112	53	[	[	-LRB-
cord-263699-gosqpg3k	112	54	48	48	CD
cord-263699-gosqpg3k	112	55	]	]	-RRB-
cord-263699-gosqpg3k	112	56	.	.	.
cord-263699-gosqpg3k	113	1	Moreover	moreover	RB
cord-263699-gosqpg3k	113	2	,	,	,
cord-263699-gosqpg3k	113	3	considering	consider	VBG
cord-263699-gosqpg3k	113	4	that	that	IN
cord-263699-gosqpg3k	113	5	depletion	depletion	NN
cord-263699-gosqpg3k	113	6	of	of	IN
cord-263699-gosqpg3k	113	7	other	other	JJ
cord-263699-gosqpg3k	113	8	elements	element	NNS
cord-263699-gosqpg3k	113	9	involved	involve	VBN
cord-263699-gosqpg3k	113	10	in	in	IN
cord-263699-gosqpg3k	113	11	COPI	COPI	NNP
cord-263699-gosqpg3k	113	12	transport	transport	NN
cord-263699-gosqpg3k	113	13	,	,	,
cord-263699-gosqpg3k	113	14	such	such	JJ
cord-263699-gosqpg3k	113	15	as	as	IN
cord-263699-gosqpg3k	113	16	the	the	DT
cord-263699-gosqpg3k	113	17	COP	COP	NNP
cord-263699-gosqpg3k	113	18	-	-	HYPH
cord-263699-gosqpg3k	113	19	β	β	NNP
cord-263699-gosqpg3k	113	20	subunit	subunit	NN
cord-263699-gosqpg3k	113	21	or	or	CC
cord-263699-gosqpg3k	113	22	the	the	DT
cord-263699-gosqpg3k	113	23	simultaneous	simultaneous	JJ
cord-263699-gosqpg3k	113	24	depletion	depletion	NN
cord-263699-gosqpg3k	113	25	of	of	IN
cord-263699-gosqpg3k	113	26	Arf1	Arf1	NNP
cord-263699-gosqpg3k	113	27	and	and	CC
cord-263699-gosqpg3k	113	28	Arf4	Arf4	NNP
cord-263699-gosqpg3k	113	29	,	,	,
cord-263699-gosqpg3k	113	30	largely	largely	RB
cord-263699-gosqpg3k	113	31	reduce	reduce	VB
cord-263699-gosqpg3k	113	32	the	the	DT
cord-263699-gosqpg3k	113	33	accumulation	accumulation	NN
cord-263699-gosqpg3k	113	34	of	of	IN
cord-263699-gosqpg3k	113	35	the	the	DT
cord-263699-gosqpg3k	113	36	C	C	NNP
cord-263699-gosqpg3k	113	37	protein	protein	NN
cord-263699-gosqpg3k	113	38	in	in	IN
cord-263699-gosqpg3k	113	39	LDs	LDs	NNP
cord-263699-gosqpg3k	113	40	,	,	,
cord-263699-gosqpg3k	113	41	it	-PRON-	PRP
cord-263699-gosqpg3k	113	42	was	be	VBD
cord-263699-gosqpg3k	113	43	suggested	suggest	VBN
cord-263699-gosqpg3k	113	44	that	that	IN
cord-263699-gosqpg3k	113	45	the	the	DT
cord-263699-gosqpg3k	113	46	dynamic	dynamic	JJ
cord-263699-gosqpg3k	113	47	delivery	delivery	NN
cord-263699-gosqpg3k	113	48	of	of	IN
cord-263699-gosqpg3k	113	49	the	the	DT
cord-263699-gosqpg3k	113	50	C	C	NNP
cord-263699-gosqpg3k	113	51	protein	protein	NN
cord-263699-gosqpg3k	113	52	from	from	IN
cord-263699-gosqpg3k	113	53	ER	ER	NNP
cord-263699-gosqpg3k	113	54	to	to	IN
cord-263699-gosqpg3k	113	55	LDs	LDs	NNP
cord-263699-gosqpg3k	113	56	is	be	VBZ
cord-263699-gosqpg3k	113	57	regulated	regulate	VBN
cord-263699-gosqpg3k	113	58	by	by	IN
cord-263699-gosqpg3k	113	59	the	the	DT
cord-263699-gosqpg3k	113	60	COPI	COPI	NNP
cord-263699-gosqpg3k	113	61	complex	complex	JJ
cord-263699-gosqpg3k	113	62	through	through	IN
cord-263699-gosqpg3k	113	63	the	the	DT
cord-263699-gosqpg3k	113	64	GBF1-mediated	gbf1-mediated	JJ
cord-263699-gosqpg3k	113	65	activation	activation	NN
cord-263699-gosqpg3k	113	66	of	of	IN
cord-263699-gosqpg3k	113	67	Arf1	Arf1	NNP
cord-263699-gosqpg3k	113	68	and	and	CC
cord-263699-gosqpg3k	113	69	Arf4	Arf4	NNP
cord-263699-gosqpg3k	113	70	.	.	.
cord-263699-gosqpg3k	114	1	On	on	IN
cord-263699-gosqpg3k	114	2	the	the	DT
cord-263699-gosqpg3k	114	3	other	other	JJ
cord-263699-gosqpg3k	114	4	hand	hand	NN
cord-263699-gosqpg3k	114	5	,	,	,
cord-263699-gosqpg3k	114	6	and	and	CC
cord-263699-gosqpg3k	114	7	similar	similar	JJ
cord-263699-gosqpg3k	114	8	to	to	IN
cord-263699-gosqpg3k	114	9	DENV	DENV	NNP
cord-263699-gosqpg3k	114	10	,	,	,
cord-263699-gosqpg3k	114	11	in	in	IN
cord-263699-gosqpg3k	114	12	TBEV	TBEV	NNP
cord-263699-gosqpg3k	114	13	-	-	HYPH
cord-263699-gosqpg3k	114	14	infected	infect	VBN
cord-263699-gosqpg3k	114	15	cells	cell	NNS
cord-263699-gosqpg3k	114	16	,	,	,
cord-263699-gosqpg3k	114	17	the	the	DT
cord-263699-gosqpg3k	114	18	inhibition	inhibition	NN
cord-263699-gosqpg3k	114	19	of	of	IN
cord-263699-gosqpg3k	114	20	GBF1	GBF1	NNP
cord-263699-gosqpg3k	114	21	also	also	RB
cord-263699-gosqpg3k	114	22	showed	show	VBD
cord-263699-gosqpg3k	114	23	an	an	DT
cord-263699-gosqpg3k	114	24	alteration	alteration	NN
cord-263699-gosqpg3k	114	25	in	in	IN
cord-263699-gosqpg3k	114	26	the	the	DT
cord-263699-gosqpg3k	114	27	transport	transport	NN
cord-263699-gosqpg3k	114	28	of	of	IN
cord-263699-gosqpg3k	114	29	the	the	DT
cord-263699-gosqpg3k	114	30	structural	structural	JJ
cord-263699-gosqpg3k	114	31	prM	prm	NN
cord-263699-gosqpg3k	114	32	,	,	,
cord-263699-gosqpg3k	114	33	E	E	NNP
cord-263699-gosqpg3k	114	34	,	,	,
cord-263699-gosqpg3k	114	35	and	and	CC
cord-263699-gosqpg3k	114	36	C	c	NN
cord-263699-gosqpg3k	114	37	proteins	protein	NNS
cord-263699-gosqpg3k	114	38	[	[	-LRB-
cord-263699-gosqpg3k	114	39	50	50	CD
cord-263699-gosqpg3k	114	40	]	]	-RRB-
cord-263699-gosqpg3k	114	41	.	.	.
cord-263699-gosqpg3k	115	1	Of	of	IN
cord-263699-gosqpg3k	115	2	interest	interest	NN
cord-263699-gosqpg3k	115	3	,	,	,
cord-263699-gosqpg3k	115	4	the	the	DT
cord-263699-gosqpg3k	115	5	increment	increment	NN
cord-263699-gosqpg3k	115	6	of	of	IN
cord-263699-gosqpg3k	115	7	the	the	DT
cord-263699-gosqpg3k	115	8	C	C	NNP
cord-263699-gosqpg3k	115	9	protein	protein	NN
cord-263699-gosqpg3k	115	10	transport	transport	NN
cord-263699-gosqpg3k	115	11	and	and	CC
cord-263699-gosqpg3k	115	12	the	the	DT
cord-263699-gosqpg3k	115	13	inhibition	inhibition	NN
cord-263699-gosqpg3k	115	14	of	of	IN
cord-263699-gosqpg3k	115	15	viral	viral	JJ
cord-263699-gosqpg3k	115	16	progeny	progeny	NN
cord-263699-gosqpg3k	115	17	production	production	NN
cord-263699-gosqpg3k	115	18	has	have	VBZ
cord-263699-gosqpg3k	115	19	also	also	RB
cord-263699-gosqpg3k	115	20	been	be	VBN
cord-263699-gosqpg3k	115	21	recapitulated	recapitulate	VBN
cord-263699-gosqpg3k	115	22	by	by	IN
cord-263699-gosqpg3k	115	23	treating	treat	VBG
cord-263699-gosqpg3k	115	24	TBEV	TBEV	NNP
cord-263699-gosqpg3k	115	25	-	-	HYPH
cord-263699-gosqpg3k	115	26	infected	infect	VBN
cord-263699-gosqpg3k	115	27	cells	cell	NNS
cord-263699-gosqpg3k	115	28	with	with	IN
cord-263699-gosqpg3k	115	29	interferon	interferon	NN
cord-263699-gosqpg3k	115	30	1	1	CD
cord-263699-gosqpg3k	115	31	(	(	-LRB-
cord-263699-gosqpg3k	115	32	INF1	INF1	NNP
cord-263699-gosqpg3k	115	33	)	)	-RRB-
cord-263699-gosqpg3k	115	34	,	,	,
cord-263699-gosqpg3k	115	35	through	through	IN
cord-263699-gosqpg3k	115	36	the	the	DT
cord-263699-gosqpg3k	115	37	induction	induction	NN
cord-263699-gosqpg3k	115	38	of	of	IN
cord-263699-gosqpg3k	115	39	the	the	DT
cord-263699-gosqpg3k	115	40	expression	expression	NN
cord-263699-gosqpg3k	115	41	of	of	IN
cord-263699-gosqpg3k	115	42	the	the	DT
cord-263699-gosqpg3k	115	43	viperin	viperin	NNP
cord-263699-gosqpg3k	115	44	(	(	-LRB-
cord-263699-gosqpg3k	115	45	virus	virus	NN
cord-263699-gosqpg3k	115	46	inhibitory	inhibitory	JJ
cord-263699-gosqpg3k	115	47	protein	protein	NN
cord-263699-gosqpg3k	115	48	,	,	,
cord-263699-gosqpg3k	115	49	ER	ER	NNP
cord-263699-gosqpg3k	115	50	-	-	HYPH
cord-263699-gosqpg3k	115	51	associated	associate	VBN
cord-263699-gosqpg3k	115	52	,	,	,
cord-263699-gosqpg3k	116	1	IFN	IFN	NNP
cord-263699-gosqpg3k	116	2	-	-	HYPH
cord-263699-gosqpg3k	116	3	inducible	inducible	JJ
cord-263699-gosqpg3k	116	4	)	)	-RRB-
cord-263699-gosqpg3k	116	5	protein	protein	NN
cord-263699-gosqpg3k	116	6	[	[	-LRB-
cord-263699-gosqpg3k	116	7	50	50	CD
cord-263699-gosqpg3k	116	8	]	]	-RRB-
cord-263699-gosqpg3k	116	9	;	;	:
cord-263699-gosqpg3k	117	1	viperin	viperin	NNP
cord-263699-gosqpg3k	117	2	also	also	RB
cord-263699-gosqpg3k	117	3	has	have	VBZ
cord-263699-gosqpg3k	117	4	antiviral	antiviral	JJ
cord-263699-gosqpg3k	117	5	effects	effect	NNS
cord-263699-gosqpg3k	117	6	on	on	IN
cord-263699-gosqpg3k	117	7	other	other	JJ
cord-263699-gosqpg3k	117	8	flaviviruses	flavivirus	NNS
cord-263699-gosqpg3k	117	9	such	such	JJ
cord-263699-gosqpg3k	117	10	as	as	IN
cord-263699-gosqpg3k	117	11	DENV	DENV	NNP
cord-263699-gosqpg3k	117	12	[	[	-LRB-
cord-263699-gosqpg3k	117	13	82	82	CD
cord-263699-gosqpg3k	117	14	]	]	-RRB-
cord-263699-gosqpg3k	118	1	and	and	CC
cord-263699-gosqpg3k	118	2	West	West	NNP
cord-263699-gosqpg3k	118	3	Nile	Nile	NNP
cord-263699-gosqpg3k	118	4	virus	virus	NN
cord-263699-gosqpg3k	118	5	(	(	-LRB-
cord-263699-gosqpg3k	118	6	WNV	WNV	NNP
cord-263699-gosqpg3k	118	7	)	)	-RRB-
cord-263699-gosqpg3k	118	8	[	[	-LRB-
cord-263699-gosqpg3k	118	9	83	83	CD
cord-263699-gosqpg3k	118	10	]	]	-RRB-
cord-263699-gosqpg3k	118	11	.	.	.
cord-263699-gosqpg3k	119	1	The	the	DT
cord-263699-gosqpg3k	119	2	antiviral	antiviral	JJ
cord-263699-gosqpg3k	119	3	activity	activity	NN
cord-263699-gosqpg3k	119	4	of	of	IN
cord-263699-gosqpg3k	119	5	viperin	viperin	NNP
cord-263699-gosqpg3k	119	6	seems	seem	VBZ
cord-263699-gosqpg3k	119	7	to	to	TO
cord-263699-gosqpg3k	119	8	be	be	VB
cord-263699-gosqpg3k	119	9	the	the	DT
cord-263699-gosqpg3k	119	10	result	result	NN
cord-263699-gosqpg3k	119	11	of	of	IN
cord-263699-gosqpg3k	119	12	the	the	DT
cord-263699-gosqpg3k	119	13	inhibition	inhibition	NN
cord-263699-gosqpg3k	119	14	of	of	IN
cord-263699-gosqpg3k	119	15	the	the	DT
cord-263699-gosqpg3k	119	16	GBF1	GBF1	NNP
cord-263699-gosqpg3k	119	17	activity	activity	NN
cord-263699-gosqpg3k	119	18	,	,	,
cord-263699-gosqpg3k	119	19	since	since	IN
cord-263699-gosqpg3k	119	20	overexpression	overexpression	NN
cord-263699-gosqpg3k	119	21	of	of	IN
cord-263699-gosqpg3k	119	22	this	this	DT
cord-263699-gosqpg3k	119	23	factor	factor	NN
cord-263699-gosqpg3k	119	24	was	be	VBD
cord-263699-gosqpg3k	119	25	shown	show	VBN
cord-263699-gosqpg3k	119	26	to	to	TO
cord-263699-gosqpg3k	119	27	counteract	counteract	VB
cord-263699-gosqpg3k	119	28	the	the	DT
cord-263699-gosqpg3k	119	29	effects	effect	NNS
cord-263699-gosqpg3k	119	30	of	of	IN
cord-263699-gosqpg3k	119	31	viperin	viperin	NNP
cord-263699-gosqpg3k	119	32	on	on	IN
cord-263699-gosqpg3k	119	33	the	the	DT
cord-263699-gosqpg3k	119	34	TBEV	TBEV	NNP
cord-263699-gosqpg3k	119	35	infection	infection	NN
cord-263699-gosqpg3k	119	36	[	[	-LRB-
cord-263699-gosqpg3k	119	37	50	50	CD
cord-263699-gosqpg3k	119	38	]	]	-RRB-
cord-263699-gosqpg3k	119	39	.	.	.
cord-263699-gosqpg3k	120	1	On	on	IN
cord-263699-gosqpg3k	120	2	the	the	DT
cord-263699-gosqpg3k	120	3	other	other	JJ
cord-263699-gosqpg3k	120	4	hand	hand	NN
cord-263699-gosqpg3k	120	5	,	,	,
cord-263699-gosqpg3k	120	6	it	-PRON-	PRP
cord-263699-gosqpg3k	120	7	has	have	VBZ
cord-263699-gosqpg3k	120	8	been	be	VBN
cord-263699-gosqpg3k	120	9	shown	show	VBN
cord-263699-gosqpg3k	120	10	that	that	IN
cord-263699-gosqpg3k	120	11	the	the	DT
cord-263699-gosqpg3k	120	12	simultaneous	simultaneous	JJ
cord-263699-gosqpg3k	120	13	depletion	depletion	NN
cord-263699-gosqpg3k	120	14	of	of	IN
cord-263699-gosqpg3k	120	15	Arf4	Arf4	NNP
cord-263699-gosqpg3k	120	16	and	and	CC
cord-263699-gosqpg3k	120	17	Arf5	Arf5	NNP
cord-263699-gosqpg3k	120	18	decreases	decrease	VBZ
cord-263699-gosqpg3k	120	19	the	the	DT
cord-263699-gosqpg3k	120	20	secretion	secretion	NN
cord-263699-gosqpg3k	120	21	of	of	IN
cord-263699-gosqpg3k	120	22	DENV	DENV	NNP
cord-263699-gosqpg3k	120	23	and	and	CC
cord-263699-gosqpg3k	120	24	YFV	YFV	NNP
cord-263699-gosqpg3k	120	25	particles	particle	NNS
cord-263699-gosqpg3k	120	26	,	,	,
cord-263699-gosqpg3k	120	27	without	without	IN
cord-263699-gosqpg3k	120	28	affecting	affect	VBG
cord-263699-gosqpg3k	120	29	the	the	DT
cord-263699-gosqpg3k	120	30	constitutive	constitutive	JJ
cord-263699-gosqpg3k	120	31	secretory	secretory	JJ
cord-263699-gosqpg3k	120	32	pathway	pathway	NN
cord-263699-gosqpg3k	120	33	[	[	-LRB-
cord-263699-gosqpg3k	120	34	80	80	CD
cord-263699-gosqpg3k	120	35	]	]	-RRB-
cord-263699-gosqpg3k	120	36	.	.	.
cord-263699-gosqpg3k	121	1	The	the	DT
cord-263699-gosqpg3k	121	2	fact	fact	NN
cord-263699-gosqpg3k	121	3	that	that	IN
cord-263699-gosqpg3k	121	4	these	these	DT
cord-263699-gosqpg3k	121	5	Arf	Arf	NNP
cord-263699-gosqpg3k	121	6	proteins	protein	NNS
cord-263699-gosqpg3k	121	7	can	can	MD
cord-263699-gosqpg3k	121	8	be	be	VB
cord-263699-gosqpg3k	121	9	selectively	selectively	RB
cord-263699-gosqpg3k	121	10	activated	activate	VBN
cord-263699-gosqpg3k	121	11	by	by	IN
cord-263699-gosqpg3k	121	12	GBF1	GBF1	NNP
cord-263699-gosqpg3k	121	13	,	,	,
cord-263699-gosqpg3k	121	14	and	and	CC
cord-263699-gosqpg3k	121	15	that	that	IN
cord-263699-gosqpg3k	121	16	the	the	DT
cord-263699-gosqpg3k	121	17	block	block	NN
cord-263699-gosqpg3k	121	18	in	in	IN
cord-263699-gosqpg3k	121	19	the	the	DT
cord-263699-gosqpg3k	121	20	secretion	secretion	NN
cord-263699-gosqpg3k	121	21	of	of	IN
cord-263699-gosqpg3k	121	22	DENV	DENV	NNP
cord-263699-gosqpg3k	121	23	particles	particle	NNS
cord-263699-gosqpg3k	121	24	can	can	MD
cord-263699-gosqpg3k	121	25	be	be	VB
cord-263699-gosqpg3k	121	26	replicated	replicate	VBN
cord-263699-gosqpg3k	121	27	by	by	IN
cord-263699-gosqpg3k	121	28	treatment	treatment	NN
cord-263699-gosqpg3k	121	29	of	of	IN
cord-263699-gosqpg3k	121	30	cells	cell	NNS
cord-263699-gosqpg3k	121	31	with	with	IN
cord-263699-gosqpg3k	121	32	BFA	BFA	NNP
cord-263699-gosqpg3k	121	33	,	,	,
cord-263699-gosqpg3k	121	34	suggest	suggest	VBP
cord-263699-gosqpg3k	121	35	that	that	IN
cord-263699-gosqpg3k	121	36	the	the	DT
cord-263699-gosqpg3k	121	37	secretion	secretion	NN
cord-263699-gosqpg3k	121	38	of	of	IN
cord-263699-gosqpg3k	121	39	DENV	DENV	NNP
cord-263699-gosqpg3k	121	40	particles	particle	NNS
cord-263699-gosqpg3k	121	41	to	to	IN
cord-263699-gosqpg3k	121	42	the	the	DT
cord-263699-gosqpg3k	121	43	extracellular	extracellular	JJ
cord-263699-gosqpg3k	121	44	medium	medium	NN
cord-263699-gosqpg3k	121	45	is	be	VBZ
cord-263699-gosqpg3k	121	46	GBF1-mediated	gbf1-mediate	VBN
cord-263699-gosqpg3k	121	47	and	and	CC
cord-263699-gosqpg3k	121	48	is	be	VBZ
cord-263699-gosqpg3k	121	49	dependent	dependent	JJ
cord-263699-gosqpg3k	121	50	on	on	IN
cord-263699-gosqpg3k	121	51	the	the	DT
cord-263699-gosqpg3k	121	52	activation	activation	NN
cord-263699-gosqpg3k	121	53	of	of	IN
cord-263699-gosqpg3k	121	54	Arf4	Arf4	NNP
cord-263699-gosqpg3k	121	55	and	and	CC
cord-263699-gosqpg3k	121	56	Arf5	Arf5	NNP
cord-263699-gosqpg3k	121	57	.	.	.
cord-263699-gosqpg3k	122	1	However	however	RB
cord-263699-gosqpg3k	122	2	,	,	,
cord-263699-gosqpg3k	122	3	this	this	DT
cord-263699-gosqpg3k	122	4	requirement	requirement	NN
cord-263699-gosqpg3k	122	5	is	be	VBZ
cord-263699-gosqpg3k	122	6	not	not	RB
cord-263699-gosqpg3k	122	7	shared	share	VBN
cord-263699-gosqpg3k	122	8	by	by	IN
cord-263699-gosqpg3k	122	9	all	all	DT
cord-263699-gosqpg3k	122	10	flaviviruses	flavivirus	NNS
cord-263699-gosqpg3k	122	11	since	since	IN
cord-263699-gosqpg3k	122	12	the	the	DT
cord-263699-gosqpg3k	122	13	replication	replication	NN
cord-263699-gosqpg3k	122	14	of	of	IN
cord-263699-gosqpg3k	122	15	WNV	WNV	NNP
cord-263699-gosqpg3k	122	16	is	be	VBZ
cord-263699-gosqpg3k	122	17	not	not	RB
cord-263699-gosqpg3k	122	18	affected	affect	VBN
cord-263699-gosqpg3k	122	19	by	by	IN
cord-263699-gosqpg3k	122	20	depletion	depletion	NN
cord-263699-gosqpg3k	122	21	of	of	IN
cord-263699-gosqpg3k	122	22	these	these	DT
cord-263699-gosqpg3k	122	23	Arfs	Arfs	NNP
cord-263699-gosqpg3k	122	24	[	[	-LRB-
cord-263699-gosqpg3k	122	25	80	80	CD
cord-263699-gosqpg3k	122	26	]	]	-RRB-
cord-263699-gosqpg3k	122	27	.	.	.
cord-263699-gosqpg3k	123	1	Although	although	IN
cord-263699-gosqpg3k	123	2	many	many	JJ
cord-263699-gosqpg3k	123	3	aspects	aspect	NNS
cord-263699-gosqpg3k	123	4	of	of	IN
cord-263699-gosqpg3k	123	5	the	the	DT
cord-263699-gosqpg3k	123	6	pestiviruses	pestiviruses	NNP
cord-263699-gosqpg3k	123	7	replication	replication	NN
cord-263699-gosqpg3k	123	8	cycle	cycle	NN
cord-263699-gosqpg3k	123	9	remain	remain	VBP
cord-263699-gosqpg3k	123	10	unknown	unknown	JJ
cord-263699-gosqpg3k	123	11	,	,	,
cord-263699-gosqpg3k	123	12	a	a	DT
cord-263699-gosqpg3k	123	13	recent	recent	JJ
cord-263699-gosqpg3k	123	14	study	study	NN
cord-263699-gosqpg3k	123	15	described	describe	VBD
cord-263699-gosqpg3k	123	16	that	that	IN
cord-263699-gosqpg3k	123	17	replication	replication	NN
cord-263699-gosqpg3k	123	18	of	of	IN
cord-263699-gosqpg3k	123	19	the	the	DT
cord-263699-gosqpg3k	123	20	classical	classical	JJ
cord-263699-gosqpg3k	123	21	swine	swine	NN
cord-263699-gosqpg3k	123	22	fever	fever	NN
cord-263699-gosqpg3k	123	23	virus	virus	NN
cord-263699-gosqpg3k	123	24	(	(	-LRB-
cord-263699-gosqpg3k	123	25	CSFV	CSFV	NNP
cord-263699-gosqpg3k	123	26	)	)	-RRB-
cord-263699-gosqpg3k	123	27	depends	depend	VBZ
cord-263699-gosqpg3k	123	28	on	on	IN
cord-263699-gosqpg3k	123	29	the	the	DT
cord-263699-gosqpg3k	123	30	activity	activity	NN
cord-263699-gosqpg3k	123	31	of	of	IN
cord-263699-gosqpg3k	123	32	GBF1	GBF1	NNP
cord-263699-gosqpg3k	123	33	.	.	.
cord-263699-gosqpg3k	124	1	It	-PRON-	PRP
cord-263699-gosqpg3k	124	2	was	be	VBD
cord-263699-gosqpg3k	124	3	described	describe	VBN
cord-263699-gosqpg3k	124	4	that	that	IN
cord-263699-gosqpg3k	124	5	both	both	DT
cord-263699-gosqpg3k	124	6	BFA	BFA	NNP
cord-263699-gosqpg3k	124	7	or	or	CC
cord-263699-gosqpg3k	124	8	GCA	GCA	NNP
cord-263699-gosqpg3k	124	9	are	be	VBP
cord-263699-gosqpg3k	124	10	able	able	JJ
cord-263699-gosqpg3k	124	11	to	to	TO
cord-263699-gosqpg3k	124	12	reduce	reduce	VB
cord-263699-gosqpg3k	124	13	the	the	DT
cord-263699-gosqpg3k	124	14	viral	viral	JJ
cord-263699-gosqpg3k	124	15	titers	titer	NNS
cord-263699-gosqpg3k	124	16	and	and	CC
cord-263699-gosqpg3k	124	17	the	the	DT
cord-263699-gosqpg3k	124	18	viral	viral	JJ
cord-263699-gosqpg3k	124	19	RNA	RNA	NNP
cord-263699-gosqpg3k	124	20	level	level	NN
cord-263699-gosqpg3k	124	21	,	,	,
cord-263699-gosqpg3k	124	22	and	and	CC
cord-263699-gosqpg3k	124	23	depletion	depletion	NN
cord-263699-gosqpg3k	124	24	of	of	IN
cord-263699-gosqpg3k	124	25	GBF1	GBF1	NNP
cord-263699-gosqpg3k	124	26	is	be	VBZ
cord-263699-gosqpg3k	124	27	sufficient	sufficient	JJ
cord-263699-gosqpg3k	124	28	to	to	TO
cord-263699-gosqpg3k	124	29	cause	cause	VB
cord-263699-gosqpg3k	124	30	this	this	DT
cord-263699-gosqpg3k	124	31	effect	effect	NN
cord-263699-gosqpg3k	124	32	[	[	-LRB-
cord-263699-gosqpg3k	124	33	53	53	CD
cord-263699-gosqpg3k	124	34	]	]	-RRB-
cord-263699-gosqpg3k	124	35	.	.	.
cord-263699-gosqpg3k	125	1	It	-PRON-	PRP
cord-263699-gosqpg3k	125	2	seems	seem	VBZ
cord-263699-gosqpg3k	125	3	that	that	IN
cord-263699-gosqpg3k	125	4	GBF1	GBF1	NNP
cord-263699-gosqpg3k	125	5	could	could	MD
cord-263699-gosqpg3k	125	6	facilitate	facilitate	VB
cord-263699-gosqpg3k	125	7	pestiviruses	pestiviruses	JJ
cord-263699-gosqpg3k	125	8	replication	replication	NN
cord-263699-gosqpg3k	125	9	by	by	IN
cord-263699-gosqpg3k	125	10	regulating	regulate	VBG
cord-263699-gosqpg3k	125	11	the	the	DT
cord-263699-gosqpg3k	125	12	COPI	COPI	NNP
cord-263699-gosqpg3k	125	13	-	-	HYPH
cord-263699-gosqpg3k	125	14	mediated	mediate	VBN
cord-263699-gosqpg3k	125	15	transport	transport	NN
cord-263699-gosqpg3k	125	16	,	,	,
cord-263699-gosqpg3k	125	17	since	since	IN
cord-263699-gosqpg3k	125	18	knocking	knock	VBG
cord-263699-gosqpg3k	125	19	down	down	RP
cord-263699-gosqpg3k	125	20	the	the	DT
cord-263699-gosqpg3k	125	21	expression	expression	NN
cord-263699-gosqpg3k	125	22	of	of	IN
cord-263699-gosqpg3k	125	23	Rab2	Rab2	NNP
cord-263699-gosqpg3k	125	24	,	,	,
cord-263699-gosqpg3k	125	25	a	a	DT
cord-263699-gosqpg3k	125	26	regulatory	regulatory	JJ
cord-263699-gosqpg3k	125	27	element	element	NN
cord-263699-gosqpg3k	125	28	of	of	IN
cord-263699-gosqpg3k	125	29	the	the	DT
cord-263699-gosqpg3k	125	30	retrograde	retrograde	JJ
cord-263699-gosqpg3k	125	31	transport	transport	NN
cord-263699-gosqpg3k	125	32	mediated	mediate	VBN
cord-263699-gosqpg3k	125	33	by	by	IN
cord-263699-gosqpg3k	125	34	COPI	COPI	NNP
cord-263699-gosqpg3k	125	35	[	[	-LRB-
cord-263699-gosqpg3k	125	36	84	84	CD
cord-263699-gosqpg3k	125	37	]	]	-RRB-
cord-263699-gosqpg3k	125	38	,	,	,
cord-263699-gosqpg3k	125	39	has	have	VBZ
cord-263699-gosqpg3k	125	40	been	be	VBN
cord-263699-gosqpg3k	125	41	shown	show	VBN
cord-263699-gosqpg3k	125	42	to	to	TO
cord-263699-gosqpg3k	125	43	significantly	significantly	RB
cord-263699-gosqpg3k	125	44	decrease	decrease	VB
cord-263699-gosqpg3k	125	45	the	the	DT
cord-263699-gosqpg3k	125	46	viral	viral	JJ
cord-263699-gosqpg3k	125	47	titer	titer	NN
cord-263699-gosqpg3k	125	48	and	and	CC
cord-263699-gosqpg3k	125	49	the	the	DT
cord-263699-gosqpg3k	125	50	RNA	RNA	NNP
cord-263699-gosqpg3k	125	51	level	level	NN
cord-263699-gosqpg3k	125	52	of	of	IN
cord-263699-gosqpg3k	125	53	CSFV	CSFV	NNP
cord-263699-gosqpg3k	125	54	.	.	.
cord-263699-gosqpg3k	126	1	Of	of	IN
cord-263699-gosqpg3k	126	2	interest	interest	NN
cord-263699-gosqpg3k	126	3	,	,	,
cord-263699-gosqpg3k	126	4	this	this	DT
cord-263699-gosqpg3k	126	5	transport	transport	NN
cord-263699-gosqpg3k	126	6	does	do	VBZ
cord-263699-gosqpg3k	126	7	not	not	RB
cord-263699-gosqpg3k	126	8	seem	seem	VB
cord-263699-gosqpg3k	126	9	to	to	TO
cord-263699-gosqpg3k	126	10	rely	rely	VB
cord-263699-gosqpg3k	126	11	on	on	IN
cord-263699-gosqpg3k	126	12	the	the	DT
cord-263699-gosqpg3k	126	13	activation	activation	NN
cord-263699-gosqpg3k	126	14	of	of	IN
cord-263699-gosqpg3k	126	15	Arf1	Arf1	NNP
cord-263699-gosqpg3k	126	16	,	,	,
cord-263699-gosqpg3k	126	17	since	since	IN
cord-263699-gosqpg3k	126	18	depletion	depletion	NN
cord-263699-gosqpg3k	126	19	of	of	IN
cord-263699-gosqpg3k	126	20	this	this	DT
cord-263699-gosqpg3k	126	21	factor	factor	NN
cord-263699-gosqpg3k	126	22	did	do	VBD
cord-263699-gosqpg3k	126	23	not	not	RB
cord-263699-gosqpg3k	126	24	affect	affect	VB
cord-263699-gosqpg3k	126	25	CSFV	CSFV	NNP
cord-263699-gosqpg3k	126	26	replication	replication	NN
cord-263699-gosqpg3k	126	27	[	[	-LRB-
cord-263699-gosqpg3k	126	28	53	53	CD
cord-263699-gosqpg3k	126	29	]	]	-RRB-
cord-263699-gosqpg3k	126	30	.	.	.
cord-263699-gosqpg3k	127	1	The	the	DT
cord-263699-gosqpg3k	127	2	replication	replication	NN
cord-263699-gosqpg3k	127	3	of	of	IN
cord-263699-gosqpg3k	127	4	bovine	bovine	JJ
cord-263699-gosqpg3k	127	5	viral	viral	JJ
cord-263699-gosqpg3k	127	6	diarrhea	diarrhea	NN
cord-263699-gosqpg3k	127	7	virus	virus	NN
cord-263699-gosqpg3k	127	8	(	(	-LRB-
cord-263699-gosqpg3k	127	9	BVDV	BVDV	NNP
cord-263699-gosqpg3k	127	10	)	)	-RRB-
cord-263699-gosqpg3k	127	11	,	,	,
cord-263699-gosqpg3k	127	12	the	the	DT
cord-263699-gosqpg3k	127	13	prototype	prototype	NN
cord-263699-gosqpg3k	127	14	member	member	NN
cord-263699-gosqpg3k	127	15	of	of	IN
cord-263699-gosqpg3k	127	16	the	the	DT
cord-263699-gosqpg3k	127	17	Pestivirus	Pestivirus	NNP
cord-263699-gosqpg3k	127	18	genus	genus	NN
cord-263699-gosqpg3k	127	19	,	,	,
cord-263699-gosqpg3k	127	20	was	be	VBD
cord-263699-gosqpg3k	127	21	also	also	RB
cord-263699-gosqpg3k	127	22	demonstrated	demonstrate	VBN
cord-263699-gosqpg3k	127	23	to	to	TO
cord-263699-gosqpg3k	127	24	be	be	VB
cord-263699-gosqpg3k	127	25	strongly	strongly	RB
cord-263699-gosqpg3k	127	26	inhibited	inhibit	VBN
cord-263699-gosqpg3k	127	27	in	in	IN
cord-263699-gosqpg3k	127	28	the	the	DT
cord-263699-gosqpg3k	127	29	presence	presence	NN
cord-263699-gosqpg3k	127	30	of	of	IN
cord-263699-gosqpg3k	127	31	BFA	BFA	NNP
cord-263699-gosqpg3k	127	32	[	[	-LRB-
cord-263699-gosqpg3k	127	33	54	54	CD
cord-263699-gosqpg3k	127	34	]	]	-RRB-
cord-263699-gosqpg3k	127	35	,	,	,
cord-263699-gosqpg3k	127	36	suggesting	suggest	VBG
cord-263699-gosqpg3k	127	37	that	that	IN
cord-263699-gosqpg3k	127	38	the	the	DT
cord-263699-gosqpg3k	127	39	dependence	dependence	NN
cord-263699-gosqpg3k	127	40	on	on	IN
cord-263699-gosqpg3k	127	41	GBF1	GBF1	NNP
cord-263699-gosqpg3k	127	42	could	could	MD
cord-263699-gosqpg3k	127	43	be	be	VB
cord-263699-gosqpg3k	127	44	a	a	DT
cord-263699-gosqpg3k	127	45	feature	feature	NN
cord-263699-gosqpg3k	127	46	shared	share	VBN
cord-263699-gosqpg3k	127	47	among	among	IN
cord-263699-gosqpg3k	127	48	different	different	JJ
cord-263699-gosqpg3k	127	49	pestiviruses	pestiviruse	NNS
cord-263699-gosqpg3k	127	50	.	.	.
cord-263699-gosqpg3k	128	1	Infection	infection	NN
cord-263699-gosqpg3k	128	2	by	by	IN
cord-263699-gosqpg3k	128	3	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	128	4	C	C	NNP
cord-263699-gosqpg3k	128	5	virus	virus	NN
cord-263699-gosqpg3k	128	6	(	(	-LRB-
cord-263699-gosqpg3k	128	7	HCV	HCV	NNP
cord-263699-gosqpg3k	128	8	)	)	-RRB-
cord-263699-gosqpg3k	128	9	,	,	,
cord-263699-gosqpg3k	128	10	the	the	DT
cord-263699-gosqpg3k	128	11	only	only	JJ
cord-263699-gosqpg3k	128	12	member	member	NN
cord-263699-gosqpg3k	128	13	of	of	IN
cord-263699-gosqpg3k	128	14	the	the	DT
cord-263699-gosqpg3k	128	15	Hepacivirus	Hepacivirus	NNP
cord-263699-gosqpg3k	128	16	genus	genus	NN
cord-263699-gosqpg3k	128	17	,	,	,
cord-263699-gosqpg3k	128	18	induces	induce	VBZ
cord-263699-gosqpg3k	128	19	an	an	DT
cord-263699-gosqpg3k	128	20	extensive	extensive	JJ
cord-263699-gosqpg3k	128	21	remodeling	remodeling	NN
cord-263699-gosqpg3k	128	22	of	of	IN
cord-263699-gosqpg3k	128	23	intracellular	intracellular	JJ
cord-263699-gosqpg3k	128	24	membranes	membrane	NNS
cord-263699-gosqpg3k	128	25	to	to	TO
cord-263699-gosqpg3k	128	26	produce	produce	VB
cord-263699-gosqpg3k	128	27	a	a	DT
cord-263699-gosqpg3k	128	28	membranous	membranous	JJ
cord-263699-gosqpg3k	128	29	web	web	NN
cord-263699-gosqpg3k	128	30	composed	compose	VBN
cord-263699-gosqpg3k	128	31	of	of	IN
cord-263699-gosqpg3k	128	32	ER	ER	NNP
cord-263699-gosqpg3k	128	33	membranes	membrane	NNS
cord-263699-gosqpg3k	128	34	,	,	,
cord-263699-gosqpg3k	128	35	LDs	LDs	NNP
cord-263699-gosqpg3k	128	36	,	,	,
cord-263699-gosqpg3k	128	37	and	and	CC
cord-263699-gosqpg3k	128	38	double	double	JJ
cord-263699-gosqpg3k	128	39	-	-	HYPH
cord-263699-gosqpg3k	128	40	membrane	membrane	NN
cord-263699-gosqpg3k	128	41	vesicles	vesicle	NNS
cord-263699-gosqpg3k	128	42	containing	contain	VBG
cord-263699-gosqpg3k	128	43	HCV	HCV	NNP
cord-263699-gosqpg3k	128	44	nonstructural	nonstructural	JJ
cord-263699-gosqpg3k	128	45	proteins	protein	NNS
cord-263699-gosqpg3k	128	46	(	(	-LRB-
cord-263699-gosqpg3k	128	47	NS3	ns3	RB
cord-263699-gosqpg3k	128	48	,	,	,
cord-263699-gosqpg3k	128	49	NS4A	NS4A	NNP
cord-263699-gosqpg3k	128	50	-	-	HYPH
cord-263699-gosqpg3k	128	51	B	B	NNP
cord-263699-gosqpg3k	128	52	,	,	,
cord-263699-gosqpg3k	128	53	NS5A	NS5A	NNP
cord-263699-gosqpg3k	128	54	-	-	HYPH
cord-263699-gosqpg3k	128	55	B	B	NNP
cord-263699-gosqpg3k	128	56	)	)	-RRB-
cord-263699-gosqpg3k	128	57	as	as	RB
cord-263699-gosqpg3k	128	58	well	well	RB
cord-263699-gosqpg3k	128	59	as	as	IN
cord-263699-gosqpg3k	128	60	the	the	DT
cord-263699-gosqpg3k	128	61	HCV	HCV	NNP
cord-263699-gosqpg3k	128	62	RNA	RNA	NNP
cord-263699-gosqpg3k	128	63	[	[	-LRB-
cord-263699-gosqpg3k	128	64	85	85	CD
cord-263699-gosqpg3k	128	65	,	,	,
cord-263699-gosqpg3k	128	66	86	86	CD
cord-263699-gosqpg3k	128	67	]	]	-RRB-
cord-263699-gosqpg3k	128	68	.	.	.
cord-263699-gosqpg3k	129	1	Although	although	IN
cord-263699-gosqpg3k	129	2	the	the	DT
cord-263699-gosqpg3k	129	3	biogenesis	biogenesis	NN
cord-263699-gosqpg3k	129	4	of	of	IN
cord-263699-gosqpg3k	129	5	this	this	DT
cord-263699-gosqpg3k	129	6	membranous	membranous	JJ
cord-263699-gosqpg3k	129	7	web	web	NN
cord-263699-gosqpg3k	129	8	is	be	VBZ
cord-263699-gosqpg3k	129	9	not	not	RB
cord-263699-gosqpg3k	129	10	well	well	RB
cord-263699-gosqpg3k	129	11	understood	understand	VBN
cord-263699-gosqpg3k	129	12	,	,	,
cord-263699-gosqpg3k	129	13	the	the	DT
cord-263699-gosqpg3k	129	14	NS4B	NS4B	NNP
cord-263699-gosqpg3k	129	15	and	and	CC
cord-263699-gosqpg3k	130	1	NS5A	NS5A	NNP
cord-263699-gosqpg3k	130	2	proteins	protein	NNS
cord-263699-gosqpg3k	130	3	appear	appear	VBP
cord-263699-gosqpg3k	130	4	to	to	TO
cord-263699-gosqpg3k	130	5	play	play	VB
cord-263699-gosqpg3k	130	6	a	a	DT
cord-263699-gosqpg3k	130	7	major	major	JJ
cord-263699-gosqpg3k	130	8	role	role	NN
cord-263699-gosqpg3k	130	9	in	in	IN
cord-263699-gosqpg3k	130	10	the	the	DT
cord-263699-gosqpg3k	130	11	induction	induction	NN
cord-263699-gosqpg3k	130	12	of	of	IN
cord-263699-gosqpg3k	130	13	membrane	membrane	NN
cord-263699-gosqpg3k	130	14	rearrangements	rearrangement	NNS
cord-263699-gosqpg3k	130	15	[	[	-LRB-
cord-263699-gosqpg3k	130	16	87	87	CD
cord-263699-gosqpg3k	130	17	,	,	,
cord-263699-gosqpg3k	130	18	88	88	CD
cord-263699-gosqpg3k	130	19	]	]	-RRB-
cord-263699-gosqpg3k	130	20	.	.	.
cord-263699-gosqpg3k	131	1	Once	once	RB
cord-263699-gosqpg3k	131	2	the	the	DT
cord-263699-gosqpg3k	131	3	web	web	NN
cord-263699-gosqpg3k	131	4	is	be	VBZ
cord-263699-gosqpg3k	131	5	formed	form	VBN
cord-263699-gosqpg3k	131	6	,	,	,
cord-263699-gosqpg3k	131	7	the	the	DT
cord-263699-gosqpg3k	131	8	NS5B	NS5B	NNP
cord-263699-gosqpg3k	131	9	protein	protein	NN
cord-263699-gosqpg3k	131	10	(	(	-LRB-
cord-263699-gosqpg3k	131	11	RdRp	RdRp	NNP
cord-263699-gosqpg3k	131	12	)	)	-RRB-
cord-263699-gosqpg3k	131	13	directs	direct	VBZ
cord-263699-gosqpg3k	131	14	the	the	DT
cord-263699-gosqpg3k	131	15	replication	replication	NN
cord-263699-gosqpg3k	131	16	of	of	IN
cord-263699-gosqpg3k	131	17	the	the	DT
cord-263699-gosqpg3k	131	18	viral	viral	JJ
cord-263699-gosqpg3k	131	19	positive	positive	JJ
cord-263699-gosqpg3k	131	20	-	-	HYPH
cord-263699-gosqpg3k	131	21	sense	sense	NN
cord-263699-gosqpg3k	131	22	RNA	RNA	NNP
cord-263699-gosqpg3k	131	23	genome	genome	NN
cord-263699-gosqpg3k	131	24	.	.	.
cord-263699-gosqpg3k	132	1	Detailed	detailed	JJ
cord-263699-gosqpg3k	132	2	knowledge	knowledge	NN
cord-263699-gosqpg3k	132	3	about	about	IN
cord-263699-gosqpg3k	132	4	the	the	DT
cord-263699-gosqpg3k	132	5	individual	individual	JJ
cord-263699-gosqpg3k	132	6	steps	step	NNS
cord-263699-gosqpg3k	132	7	of	of	IN
cord-263699-gosqpg3k	132	8	HCV	HCV	NNP
cord-263699-gosqpg3k	132	9	particles	particle	NNS
cord-263699-gosqpg3k	132	10	assembly	assembly	NN
cord-263699-gosqpg3k	132	11	is	be	VBZ
cord-263699-gosqpg3k	132	12	lacking	lack	VBG
cord-263699-gosqpg3k	132	13	;	;	:
cord-263699-gosqpg3k	132	14	however	however	RB
cord-263699-gosqpg3k	132	15	,	,	,
cord-263699-gosqpg3k	132	16	it	-PRON-	PRP
cord-263699-gosqpg3k	132	17	is	be	VBZ
cord-263699-gosqpg3k	132	18	generally	generally	RB
cord-263699-gosqpg3k	132	19	assumed	assume	VBN
cord-263699-gosqpg3k	132	20	that	that	IN
cord-263699-gosqpg3k	132	21	nucleocapsid	nucleocapsid	NN
cord-263699-gosqpg3k	132	22	formation	formation	NN
cord-263699-gosqpg3k	132	23	and	and	CC
cord-263699-gosqpg3k	132	24	budding	budding	NN
cord-263699-gosqpg3k	132	25	are	be	VBP
cord-263699-gosqpg3k	132	26	spatially	spatially	RB
cord-263699-gosqpg3k	132	27	and	and	CC
cord-263699-gosqpg3k	132	28	temporally	temporally	RB
cord-263699-gosqpg3k	132	29	linked	link	VBN
cord-263699-gosqpg3k	132	30	events	event	NNS
cord-263699-gosqpg3k	132	31	occurring	occur	VBG
cord-263699-gosqpg3k	132	32	in	in	IN
cord-263699-gosqpg3k	132	33	an	an	DT
cord-263699-gosqpg3k	132	34	ER	er	NN
cord-263699-gosqpg3k	132	35	-	-	HYPH
cord-263699-gosqpg3k	132	36	derived	derive	VBN
cord-263699-gosqpg3k	132	37	compartment	compartment	NN
cord-263699-gosqpg3k	132	38	[	[	-LRB-
cord-263699-gosqpg3k	132	39	85	85	CD
cord-263699-gosqpg3k	132	40	,	,	,
cord-263699-gosqpg3k	132	41	86	86	CD
cord-263699-gosqpg3k	132	42	,	,	,
cord-263699-gosqpg3k	132	43	89	89	CD
cord-263699-gosqpg3k	132	44	]	]	-RRB-
cord-263699-gosqpg3k	132	45	.	.	.
cord-263699-gosqpg3k	133	1	In	in	IN
cord-263699-gosqpg3k	133	2	this	this	DT
cord-263699-gosqpg3k	133	3	regard	regard	NN
cord-263699-gosqpg3k	133	4	,	,	,
cord-263699-gosqpg3k	133	5	it	-PRON-	PRP
cord-263699-gosqpg3k	133	6	has	have	VBZ
cord-263699-gosqpg3k	133	7	been	be	VBN
cord-263699-gosqpg3k	133	8	reported	report	VBN
cord-263699-gosqpg3k	133	9	that	that	IN
cord-263699-gosqpg3k	133	10	GBF1	GBF1	NNP
cord-263699-gosqpg3k	133	11	facilitates	facilitate	VBZ
cord-263699-gosqpg3k	133	12	multiple	multiple	JJ
cord-263699-gosqpg3k	133	13	steps	step	NNS
cord-263699-gosqpg3k	133	14	of	of	IN
cord-263699-gosqpg3k	133	15	HCV	HCV	NNP
cord-263699-gosqpg3k	133	16	infection	infection	NN
cord-263699-gosqpg3k	133	17	,	,	,
cord-263699-gosqpg3k	133	18	including	include	VBG
cord-263699-gosqpg3k	133	19	the	the	DT
cord-263699-gosqpg3k	133	20	replication	replication	NN
cord-263699-gosqpg3k	133	21	of	of	IN
cord-263699-gosqpg3k	133	22	viral	viral	JJ
cord-263699-gosqpg3k	133	23	RNA	RNA	NNP
cord-263699-gosqpg3k	133	24	[	[	-LRB-
cord-263699-gosqpg3k	133	25	54	54	CD
cord-263699-gosqpg3k	133	26	,	,	,
cord-263699-gosqpg3k	133	27	55	55	CD
cord-263699-gosqpg3k	133	28	]	]	-RRB-
cord-263699-gosqpg3k	133	29	.	.	.
cord-263699-gosqpg3k	134	1	A	a	DT
cord-263699-gosqpg3k	134	2	decrement	decrement	NN
cord-263699-gosqpg3k	134	3	in	in	IN
cord-263699-gosqpg3k	134	4	the	the	DT
cord-263699-gosqpg3k	134	5	levels	level	NNS
cord-263699-gosqpg3k	134	6	of	of	IN
cord-263699-gosqpg3k	134	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	134	8	was	be	VBD
cord-263699-gosqpg3k	134	9	found	find	VBN
cord-263699-gosqpg3k	134	10	to	to	TO
cord-263699-gosqpg3k	134	11	diminish	diminish	VB
cord-263699-gosqpg3k	134	12	the	the	DT
cord-263699-gosqpg3k	134	13	expression	expression	NN
cord-263699-gosqpg3k	134	14	of	of	IN
cord-263699-gosqpg3k	134	15	NS5A	NS5A	NNP
cord-263699-gosqpg3k	134	16	,	,	,
cord-263699-gosqpg3k	134	17	a	a	DT
cord-263699-gosqpg3k	134	18	multifunctional	multifunctional	JJ
cord-263699-gosqpg3k	134	19	protein	protein	NN
cord-263699-gosqpg3k	134	20	that	that	WDT
cord-263699-gosqpg3k	134	21	modulates	modulate	VBZ
cord-263699-gosqpg3k	134	22	the	the	DT
cord-263699-gosqpg3k	134	23	viral	viral	JJ
cord-263699-gosqpg3k	134	24	polymerase	polymerase	NN
cord-263699-gosqpg3k	134	25	NS5B	NS5B	''
cord-263699-gosqpg3k	134	26	;	;	:
cord-263699-gosqpg3k	134	27	however	however	RB
cord-263699-gosqpg3k	134	28	,	,	,
cord-263699-gosqpg3k	134	29	most	most	JJS
cord-263699-gosqpg3k	134	30	of	of	IN
cord-263699-gosqpg3k	134	31	the	the	DT
cord-263699-gosqpg3k	134	32	effect	effect	NN
cord-263699-gosqpg3k	134	33	on	on	IN
cord-263699-gosqpg3k	134	34	virus	virus	NN
cord-263699-gosqpg3k	134	35	replication	replication	NN
cord-263699-gosqpg3k	134	36	seems	seem	VBZ
cord-263699-gosqpg3k	134	37	to	to	TO
cord-263699-gosqpg3k	134	38	be	be	VB
cord-263699-gosqpg3k	134	39	related	relate	VBN
cord-263699-gosqpg3k	134	40	to	to	IN
cord-263699-gosqpg3k	134	41	the	the	DT
cord-263699-gosqpg3k	134	42	role	role	NN
cord-263699-gosqpg3k	134	43	of	of	IN
cord-263699-gosqpg3k	134	44	GBF1	GBF1	NNP
cord-263699-gosqpg3k	134	45	in	in	IN
cord-263699-gosqpg3k	134	46	the	the	DT
cord-263699-gosqpg3k	134	47	formation	formation	NN
cord-263699-gosqpg3k	134	48	and	and	CC
cord-263699-gosqpg3k	134	49	function	function	NN
cord-263699-gosqpg3k	134	50	of	of	IN
cord-263699-gosqpg3k	134	51	the	the	DT
cord-263699-gosqpg3k	134	52	membranous	membranous	JJ
cord-263699-gosqpg3k	134	53	web	web	NN
cord-263699-gosqpg3k	134	54	where	where	WRB
cord-263699-gosqpg3k	134	55	the	the	DT
cord-263699-gosqpg3k	134	56	replication	replication	NN
cord-263699-gosqpg3k	134	57	complexes	complex	NNS
cord-263699-gosqpg3k	134	58	of	of	IN
cord-263699-gosqpg3k	134	59	HCV	HCV	NNP
cord-263699-gosqpg3k	134	60	assemble	assemble	VBP
cord-263699-gosqpg3k	134	61	[	[	-LRB-
cord-263699-gosqpg3k	134	62	54	54	CD
cord-263699-gosqpg3k	134	63	]	]	-RRB-
cord-263699-gosqpg3k	134	64	.	.	.
cord-263699-gosqpg3k	135	1	GBF1	GBF1	NNP
cord-263699-gosqpg3k	135	2	inhibition	inhibition	NN
cord-263699-gosqpg3k	135	3	neither	neither	DT
cord-263699-gosqpg3k	135	4	disrupts	disrupt	VBZ
cord-263699-gosqpg3k	135	5	the	the	DT
cord-263699-gosqpg3k	135	6	preformed	preformed	JJ
cord-263699-gosqpg3k	135	7	membranous	membranous	JJ
cord-263699-gosqpg3k	135	8	webs	web	NNS
cord-263699-gosqpg3k	135	9	of	of	IN
cord-263699-gosqpg3k	135	10	HCV	HCV	NNP
cord-263699-gosqpg3k	135	11	nor	nor	CC
cord-263699-gosqpg3k	135	12	blocks	block	VBZ
cord-263699-gosqpg3k	135	13	the	the	DT
cord-263699-gosqpg3k	135	14	formation	formation	NN
cord-263699-gosqpg3k	135	15	of	of	IN
cord-263699-gosqpg3k	135	16	novel	novel	JJ
cord-263699-gosqpg3k	135	17	membranous	membranous	JJ
cord-263699-gosqpg3k	135	18	web	web	NN
cord-263699-gosqpg3k	135	19	structures	structure	NNS
cord-263699-gosqpg3k	135	20	,	,	,
cord-263699-gosqpg3k	135	21	but	but	CC
cord-263699-gosqpg3k	135	22	it	-PRON-	PRP
cord-263699-gosqpg3k	135	23	rather	rather	RB
cord-263699-gosqpg3k	135	24	affects	affect	VBZ
cord-263699-gosqpg3k	135	25	the	the	DT
cord-263699-gosqpg3k	135	26	maturation	maturation	NN
cord-263699-gosqpg3k	135	27	of	of	IN
cord-263699-gosqpg3k	135	28	these	these	DT
cord-263699-gosqpg3k	135	29	viral	viral	JJ
cord-263699-gosqpg3k	135	30	organelles	organelle	NNS
cord-263699-gosqpg3k	135	31	,	,	,
cord-263699-gosqpg3k	135	32	which	which	WDT
cord-263699-gosqpg3k	135	33	exhibit	exhibit	VBP
cord-263699-gosqpg3k	135	34	a	a	DT
cord-263699-gosqpg3k	135	35	smaller	small	JJR
cord-263699-gosqpg3k	135	36	and	and	CC
cord-263699-gosqpg3k	135	37	less	less	RBR
cord-263699-gosqpg3k	135	38	organized	organized	JJ
cord-263699-gosqpg3k	135	39	structure	structure	NN
cord-263699-gosqpg3k	135	40	during	during	IN
cord-263699-gosqpg3k	135	41	the	the	DT
cord-263699-gosqpg3k	135	42	inhibition	inhibition	NN
cord-263699-gosqpg3k	135	43	of	of	IN
cord-263699-gosqpg3k	135	44	this	this	DT
cord-263699-gosqpg3k	135	45	factor	factor	NN
cord-263699-gosqpg3k	135	46	[	[	-LRB-
cord-263699-gosqpg3k	135	47	54	54	CD
cord-263699-gosqpg3k	135	48	,	,	,
cord-263699-gosqpg3k	135	49	55	55	CD
cord-263699-gosqpg3k	135	50	]	]	-RRB-
cord-263699-gosqpg3k	135	51	.	.	.
cord-263699-gosqpg3k	136	1	In	in	IN
cord-263699-gosqpg3k	136	2	this	this	DT
cord-263699-gosqpg3k	136	3	regard	regard	NN
cord-263699-gosqpg3k	136	4	,	,	,
cord-263699-gosqpg3k	136	5	it	-PRON-	PRP
cord-263699-gosqpg3k	136	6	was	be	VBD
cord-263699-gosqpg3k	136	7	reported	report	VBN
cord-263699-gosqpg3k	136	8	that	that	IN
cord-263699-gosqpg3k	136	9	the	the	DT
cord-263699-gosqpg3k	136	10	inhibition	inhibition	NN
cord-263699-gosqpg3k	136	11	of	of	IN
cord-263699-gosqpg3k	136	12	GBF1	GBF1	NNP
cord-263699-gosqpg3k	136	13	induces	induce	VBZ
cord-263699-gosqpg3k	136	14	a	a	DT
cord-263699-gosqpg3k	136	15	change	change	NN
cord-263699-gosqpg3k	136	16	in	in	IN
cord-263699-gosqpg3k	136	17	the	the	DT
cord-263699-gosqpg3k	136	18	intracellular	intracellular	JJ
cord-263699-gosqpg3k	136	19	localization	localization	NN
cord-263699-gosqpg3k	136	20	of	of	IN
cord-263699-gosqpg3k	136	21	NS5A	NS5A	NNP
cord-263699-gosqpg3k	136	22	and	and	CC
cord-263699-gosqpg3k	136	23	NS3	ns3	RB
cord-263699-gosqpg3k	136	24	(	(	-LRB-
cord-263699-gosqpg3k	136	25	viral	viral	JJ
cord-263699-gosqpg3k	136	26	protease	protease	NN
cord-263699-gosqpg3k	136	27	)	)	-RRB-
cord-263699-gosqpg3k	136	28	from	from	IN
cord-263699-gosqpg3k	136	29	their	-PRON-	PRP$
cord-263699-gosqpg3k	136	30	usual	usual	JJ
cord-263699-gosqpg3k	136	31	location	location	NN
cord-263699-gosqpg3k	136	32	in	in	IN
cord-263699-gosqpg3k	136	33	the	the	DT
cord-263699-gosqpg3k	136	34	replication	replication	NN
cord-263699-gosqpg3k	136	35	complexes	complex	NNS
cord-263699-gosqpg3k	136	36	to	to	IN
cord-263699-gosqpg3k	136	37	the	the	DT
cord-263699-gosqpg3k	136	38	rims	rim	NNS
cord-263699-gosqpg3k	136	39	of	of	IN
cord-263699-gosqpg3k	136	40	LDs	LDs	NNP
cord-263699-gosqpg3k	136	41	[	[	-LRB-
cord-263699-gosqpg3k	136	42	90	90	CD
cord-263699-gosqpg3k	136	43	]	]	-RRB-
cord-263699-gosqpg3k	136	44	,	,	,
cord-263699-gosqpg3k	136	45	suggesting	suggest	VBG
cord-263699-gosqpg3k	136	46	that	that	IN
cord-263699-gosqpg3k	136	47	GBF1	GBF1	NNP
cord-263699-gosqpg3k	136	48	could	could	MD
cord-263699-gosqpg3k	136	49	mediate	mediate	VB
cord-263699-gosqpg3k	136	50	the	the	DT
cord-263699-gosqpg3k	136	51	transport	transport	NN
cord-263699-gosqpg3k	136	52	of	of	IN
cord-263699-gosqpg3k	136	53	non	non	JJ
cord-263699-gosqpg3k	136	54	-	-	JJ
cord-263699-gosqpg3k	136	55	structural	structural	JJ
cord-263699-gosqpg3k	136	56	viral	viral	JJ
cord-263699-gosqpg3k	136	57	proteins	protein	NNS
cord-263699-gosqpg3k	136	58	and	and	CC
cord-263699-gosqpg3k	136	59	perhaps	perhaps	RB
cord-263699-gosqpg3k	136	60	cellular	cellular	JJ
cord-263699-gosqpg3k	136	61	proteins	protein	NNS
cord-263699-gosqpg3k	136	62	to	to	IN
cord-263699-gosqpg3k	136	63	these	these	DT
cord-263699-gosqpg3k	136	64	sites	site	NNS
cord-263699-gosqpg3k	136	65	.	.	.
cord-263699-gosqpg3k	137	1	In	in	IN
cord-263699-gosqpg3k	137	2	support	support	NN
cord-263699-gosqpg3k	137	3	of	of	IN
cord-263699-gosqpg3k	137	4	this	this	DT
cord-263699-gosqpg3k	137	5	possibility	possibility	NN
cord-263699-gosqpg3k	137	6	,	,	,
cord-263699-gosqpg3k	137	7	it	-PRON-	PRP
cord-263699-gosqpg3k	137	8	has	have	VBZ
cord-263699-gosqpg3k	137	9	been	be	VBN
cord-263699-gosqpg3k	137	10	found	find	VBN
cord-263699-gosqpg3k	137	11	that	that	IN
cord-263699-gosqpg3k	137	12	while	while	IN
cord-263699-gosqpg3k	137	13	a	a	DT
cord-263699-gosqpg3k	137	14	BFA	BFA	NNP
cord-263699-gosqpg3k	137	15	-	-	HYPH
cord-263699-gosqpg3k	137	16	resistant	resistant	JJ
cord-263699-gosqpg3k	137	17	GBF1	GBF1	NNP
cord-263699-gosqpg3k	137	18	mutant	mutant	NN
cord-263699-gosqpg3k	137	19	could	could	MD
cord-263699-gosqpg3k	137	20	revert	revert	VB
cord-263699-gosqpg3k	137	21	the	the	DT
cord-263699-gosqpg3k	137	22	effects	effect	NNS
cord-263699-gosqpg3k	137	23	of	of	IN
cord-263699-gosqpg3k	137	24	BFA	BFA	NNP
cord-263699-gosqpg3k	137	25	on	on	IN
cord-263699-gosqpg3k	137	26	HCV	HCV	NNP
cord-263699-gosqpg3k	137	27	,	,	,
cord-263699-gosqpg3k	137	28	an	an	DT
cord-263699-gosqpg3k	137	29	inactive	inactive	JJ
cord-263699-gosqpg3k	137	30	mutant	mutant	NN
cord-263699-gosqpg3k	137	31	or	or	CC
cord-263699-gosqpg3k	137	32	a	a	DT
cord-263699-gosqpg3k	137	33	truncated	truncated	JJ
cord-263699-gosqpg3k	137	34	form	form	NN
cord-263699-gosqpg3k	137	35	of	of	IN
cord-263699-gosqpg3k	137	36	GBF1	GBF1	NNP
cord-263699-gosqpg3k	137	37	lacking	lack	VBG
cord-263699-gosqpg3k	137	38	the	the	DT
cord-263699-gosqpg3k	137	39	catalytic	catalytic	JJ
cord-263699-gosqpg3k	137	40	Sec7	Sec7	NNP
cord-263699-gosqpg3k	137	41	domain	domain	NN
cord-263699-gosqpg3k	137	42	were	be	VBD
cord-263699-gosqpg3k	137	43	unable	unable	JJ
cord-263699-gosqpg3k	137	44	to	to	TO
cord-263699-gosqpg3k	137	45	maintain	maintain	VB
cord-263699-gosqpg3k	137	46	the	the	DT
cord-263699-gosqpg3k	137	47	replication	replication	NN
cord-263699-gosqpg3k	137	48	of	of	IN
cord-263699-gosqpg3k	137	49	HCV	HCV	NNP
cord-263699-gosqpg3k	137	50	in	in	IN
cord-263699-gosqpg3k	137	51	the	the	DT
cord-263699-gosqpg3k	137	52	presence	presence	NN
cord-263699-gosqpg3k	137	53	of	of	IN
cord-263699-gosqpg3k	137	54	BFA	BFA	NNP
cord-263699-gosqpg3k	137	55	[	[	-LRB-
cord-263699-gosqpg3k	137	56	54	54	CD
cord-263699-gosqpg3k	137	57	,	,	,
cord-263699-gosqpg3k	137	58	91	91	CD
cord-263699-gosqpg3k	137	59	]	]	-RRB-
cord-263699-gosqpg3k	137	60	;	;	:
cord-263699-gosqpg3k	137	61	this	this	DT
cord-263699-gosqpg3k	137	62	suggests	suggest	VBZ
cord-263699-gosqpg3k	137	63	that	that	IN
cord-263699-gosqpg3k	137	64	the	the	DT
cord-263699-gosqpg3k	137	65	role	role	NN
cord-263699-gosqpg3k	137	66	of	of	IN
cord-263699-gosqpg3k	137	67	GBF1	GBF1	NNP
cord-263699-gosqpg3k	137	68	depends	depend	VBZ
cord-263699-gosqpg3k	137	69	on	on	IN
cord-263699-gosqpg3k	137	70	its	-PRON-	PRP$
cord-263699-gosqpg3k	137	71	capacity	capacity	NN
cord-263699-gosqpg3k	137	72	to	to	TO
cord-263699-gosqpg3k	137	73	activate	activate	VB
cord-263699-gosqpg3k	137	74	Arf	Arf	NNP
cord-263699-gosqpg3k	137	75	proteins	protein	NNS
cord-263699-gosqpg3k	137	76	.	.	.
cord-263699-gosqpg3k	138	1	However	however	RB
cord-263699-gosqpg3k	138	2	,	,	,
cord-263699-gosqpg3k	138	3	in	in	IN
cord-263699-gosqpg3k	138	4	a	a	DT
cord-263699-gosqpg3k	138	5	contrasting	contrast	VBG
cord-263699-gosqpg3k	138	6	observation	observation	NN
cord-263699-gosqpg3k	138	7	,	,	,
cord-263699-gosqpg3k	138	8	the	the	DT
cord-263699-gosqpg3k	138	9	expression	expression	NN
cord-263699-gosqpg3k	138	10	of	of	IN
cord-263699-gosqpg3k	138	11	NS5A	NS5A	NNP
cord-263699-gosqpg3k	138	12	was	be	VBD
cord-263699-gosqpg3k	138	13	reported	report	VBN
cord-263699-gosqpg3k	138	14	to	to	TO
cord-263699-gosqpg3k	138	15	downregulate	downregulate	VB
cord-263699-gosqpg3k	138	16	the	the	DT
cord-263699-gosqpg3k	138	17	activation	activation	NN
cord-263699-gosqpg3k	138	18	of	of	IN
cord-263699-gosqpg3k	138	19	Arf1	Arf1	NNP
cord-263699-gosqpg3k	138	20	[	[	-LRB-
cord-263699-gosqpg3k	138	21	90	90	CD
cord-263699-gosqpg3k	138	22	]	]	-RRB-
cord-263699-gosqpg3k	138	23	.	.	.
cord-263699-gosqpg3k	139	1	Arf1	Arf1	NNP
cord-263699-gosqpg3k	139	2	activation	activation	NN
cord-263699-gosqpg3k	139	3	has	have	VBZ
cord-263699-gosqpg3k	139	4	also	also	RB
cord-263699-gosqpg3k	139	5	been	be	VBN
cord-263699-gosqpg3k	139	6	shown	show	VBN
cord-263699-gosqpg3k	139	7	to	to	TO
cord-263699-gosqpg3k	139	8	be	be	VB
cord-263699-gosqpg3k	139	9	related	relate	VBN
cord-263699-gosqpg3k	139	10	with	with	IN
cord-263699-gosqpg3k	139	11	the	the	DT
cord-263699-gosqpg3k	139	12	viral	viral	JJ
cord-263699-gosqpg3k	139	13	assembly	assembly	NN
cord-263699-gosqpg3k	139	14	of	of	IN
cord-263699-gosqpg3k	139	15	HCV	HCV	NNP
cord-263699-gosqpg3k	139	16	through	through	IN
cord-263699-gosqpg3k	139	17	modulation	modulation	NN
cord-263699-gosqpg3k	139	18	of	of	IN
cord-263699-gosqpg3k	139	19	the	the	DT
cord-263699-gosqpg3k	139	20	recruitment	recruitment	NN
cord-263699-gosqpg3k	139	21	of	of	IN
cord-263699-gosqpg3k	139	22	the	the	DT
cord-263699-gosqpg3k	139	23	adipose	adipose	JJ
cord-263699-gosqpg3k	139	24	differentiation	differentiation	NN
cord-263699-gosqpg3k	139	25	-	-	HYPH
cord-263699-gosqpg3k	139	26	related	relate	VBN
cord-263699-gosqpg3k	139	27	protein	protein	NN
cord-263699-gosqpg3k	139	28	(	(	-LRB-
cord-263699-gosqpg3k	139	29	ADRP	ADRP	NNP
cord-263699-gosqpg3k	139	30	)	)	-RRB-
cord-263699-gosqpg3k	139	31	to	to	IN
cord-263699-gosqpg3k	139	32	LDs	LDs	NNP
cord-263699-gosqpg3k	139	33	.	.	.
cord-263699-gosqpg3k	140	1	ADRP	ADRP	NNP
cord-263699-gosqpg3k	140	2	,	,	,
cord-263699-gosqpg3k	140	3	a	a	DT
cord-263699-gosqpg3k	140	4	member	member	NN
cord-263699-gosqpg3k	140	5	of	of	IN
cord-263699-gosqpg3k	140	6	the	the	DT
cord-263699-gosqpg3k	140	7	perilipin	perilipin	NNP
cord-263699-gosqpg3k	140	8	family	family	NN
cord-263699-gosqpg3k	140	9	,	,	,
cord-263699-gosqpg3k	140	10	is	be	VBZ
cord-263699-gosqpg3k	140	11	a	a	DT
cord-263699-gosqpg3k	140	12	major	major	JJ
cord-263699-gosqpg3k	140	13	protein	protein	NN
cord-263699-gosqpg3k	140	14	associated	associate	VBN
cord-263699-gosqpg3k	140	15	with	with	IN
cord-263699-gosqpg3k	140	16	LDs	LDs	NNP
cord-263699-gosqpg3k	140	17	in	in	IN
cord-263699-gosqpg3k	140	18	various	various	JJ
cord-263699-gosqpg3k	140	19	cell	cell	NN
cord-263699-gosqpg3k	140	20	types	type	NNS
cord-263699-gosqpg3k	140	21	.	.	.
cord-263699-gosqpg3k	141	1	This	this	DT
cord-263699-gosqpg3k	141	2	protein	protein	NN
cord-263699-gosqpg3k	141	3	has	have	VBZ
cord-263699-gosqpg3k	141	4	been	be	VBN
cord-263699-gosqpg3k	141	5	proposed	propose	VBN
cord-263699-gosqpg3k	141	6	to	to	TO
cord-263699-gosqpg3k	141	7	play	play	VB
cord-263699-gosqpg3k	141	8	a	a	DT
cord-263699-gosqpg3k	141	9	positive	positive	JJ
cord-263699-gosqpg3k	141	10	role	role	NN
cord-263699-gosqpg3k	141	11	for	for	IN
cord-263699-gosqpg3k	141	12	HCV	HCV	NNP
cord-263699-gosqpg3k	141	13	RNA	RNA	NNP
cord-263699-gosqpg3k	141	14	replication	replication	NN
cord-263699-gosqpg3k	141	15	while	while	IN
cord-263699-gosqpg3k	141	16	performing	perform	VBG
cord-263699-gosqpg3k	141	17	a	a	DT
cord-263699-gosqpg3k	141	18	negative	negative	JJ
cord-263699-gosqpg3k	141	19	function	function	NN
cord-263699-gosqpg3k	141	20	for	for	IN
cord-263699-gosqpg3k	141	21	HCV	HCV	NNP
cord-263699-gosqpg3k	141	22	assembly	assembly	NN
cord-263699-gosqpg3k	141	23	[	[	-LRB-
cord-263699-gosqpg3k	141	24	92	92	CD
cord-263699-gosqpg3k	141	25	]	]	-RRB-
cord-263699-gosqpg3k	141	26	.	.	.
cord-263699-gosqpg3k	142	1	Although	although	IN
cord-263699-gosqpg3k	142	2	the	the	DT
cord-263699-gosqpg3k	142	3	role	role	NN
cord-263699-gosqpg3k	142	4	of	of	IN
cord-263699-gosqpg3k	142	5	this	this	DT
cord-263699-gosqpg3k	142	6	protein	protein	NN
cord-263699-gosqpg3k	142	7	in	in	IN
cord-263699-gosqpg3k	142	8	RNA	RNA	NNP
cord-263699-gosqpg3k	142	9	replication	replication	NN
cord-263699-gosqpg3k	142	10	is	be	VBZ
cord-263699-gosqpg3k	142	11	unknown	unknown	JJ
cord-263699-gosqpg3k	142	12	,	,	,
cord-263699-gosqpg3k	142	13	it	-PRON-	PRP
cord-263699-gosqpg3k	142	14	has	have	VBZ
cord-263699-gosqpg3k	142	15	been	be	VBN
cord-263699-gosqpg3k	142	16	observed	observe	VBN
cord-263699-gosqpg3k	142	17	that	that	IN
cord-263699-gosqpg3k	142	18	ADRP	ADRP	NNP
cord-263699-gosqpg3k	142	19	shields	shield	VBZ
cord-263699-gosqpg3k	142	20	the	the	DT
cord-263699-gosqpg3k	142	21	recruitment	recruitment	NN
cord-263699-gosqpg3k	142	22	of	of	IN
cord-263699-gosqpg3k	142	23	the	the	DT
cord-263699-gosqpg3k	142	24	HCV	HCV	NNP
cord-263699-gosqpg3k	142	25	core	core	NN
cord-263699-gosqpg3k	142	26	protein	protein	NN
cord-263699-gosqpg3k	142	27	into	into	IN
cord-263699-gosqpg3k	142	28	LDs	LDs	NNP
cord-263699-gosqpg3k	142	29	,	,	,
cord-263699-gosqpg3k	142	30	a	a	DT
cord-263699-gosqpg3k	142	31	step	step	NN
cord-263699-gosqpg3k	142	32	essential	essential	JJ
cord-263699-gosqpg3k	142	33	for	for	IN
cord-263699-gosqpg3k	142	34	virus	virus	NN
cord-263699-gosqpg3k	142	35	morphogenesis	morphogenesis	NN
cord-263699-gosqpg3k	142	36	[	[	-LRB-
cord-263699-gosqpg3k	142	37	92	92	CD
cord-263699-gosqpg3k	142	38	,	,	,
cord-263699-gosqpg3k	142	39	93	93	CD
cord-263699-gosqpg3k	142	40	]	]	-RRB-
cord-263699-gosqpg3k	142	41	.	.	.
cord-263699-gosqpg3k	143	1	In	in	IN
cord-263699-gosqpg3k	143	2	addition	addition	NN
cord-263699-gosqpg3k	143	3	,	,	,
cord-263699-gosqpg3k	143	4	the	the	DT
cord-263699-gosqpg3k	143	5	association	association	NN
cord-263699-gosqpg3k	143	6	of	of	IN
cord-263699-gosqpg3k	143	7	ADRP	ADRP	NNP
cord-263699-gosqpg3k	143	8	with	with	IN
cord-263699-gosqpg3k	143	9	LDs	LDs	NNP
cord-263699-gosqpg3k	143	10	has	have	VBZ
cord-263699-gosqpg3k	143	11	been	be	VBN
cord-263699-gosqpg3k	143	12	shown	show	VBN
cord-263699-gosqpg3k	143	13	to	to	TO
cord-263699-gosqpg3k	143	14	be	be	VB
cord-263699-gosqpg3k	143	15	dependent	dependent	JJ
cord-263699-gosqpg3k	143	16	on	on	IN
cord-263699-gosqpg3k	143	17	the	the	DT
cord-263699-gosqpg3k	143	18	activation	activation	NN
cord-263699-gosqpg3k	143	19	state	state	NN
cord-263699-gosqpg3k	143	20	of	of	IN
cord-263699-gosqpg3k	143	21	Arf1	Arf1	NNP
cord-263699-gosqpg3k	143	22	.	.	.
cord-263699-gosqpg3k	144	1	Altogether	altogether	RB
cord-263699-gosqpg3k	144	2	,	,	,
cord-263699-gosqpg3k	144	3	these	these	DT
cord-263699-gosqpg3k	144	4	results	result	NNS
cord-263699-gosqpg3k	144	5	suggest	suggest	VBP
cord-263699-gosqpg3k	144	6	that	that	IN
cord-263699-gosqpg3k	144	7	during	during	IN
cord-263699-gosqpg3k	144	8	HCV	HCV	NNP
cord-263699-gosqpg3k	144	9	infection	infection	NN
cord-263699-gosqpg3k	144	10	the	the	DT
cord-263699-gosqpg3k	144	11	activation	activation	NN
cord-263699-gosqpg3k	144	12	of	of	IN
cord-263699-gosqpg3k	144	13	Arf1	Arf1	NNP
cord-263699-gosqpg3k	144	14	induced	induce	VBN
cord-263699-gosqpg3k	144	15	by	by	IN
cord-263699-gosqpg3k	144	16	GBF1	GBF1	NNP
cord-263699-gosqpg3k	144	17	promotes	promote	VBZ
cord-263699-gosqpg3k	144	18	the	the	DT
cord-263699-gosqpg3k	144	19	exportation	exportation	NN
cord-263699-gosqpg3k	144	20	of	of	IN
cord-263699-gosqpg3k	144	21	NS5A	NS5A	NNP
cord-263699-gosqpg3k	144	22	and	and	CC
cord-263699-gosqpg3k	144	23	NS3	ns3	RB
cord-263699-gosqpg3k	144	24	from	from	IN
cord-263699-gosqpg3k	144	25	the	the	DT
cord-263699-gosqpg3k	144	26	LDs	LDs	NNP
cord-263699-gosqpg3k	144	27	to	to	IN
cord-263699-gosqpg3k	144	28	the	the	DT
cord-263699-gosqpg3k	144	29	sites	site	NNS
cord-263699-gosqpg3k	144	30	where	where	WRB
cord-263699-gosqpg3k	144	31	replication	replication	NN
cord-263699-gosqpg3k	144	32	complexes	complex	NNS
cord-263699-gosqpg3k	144	33	are	be	VBP
cord-263699-gosqpg3k	144	34	located	locate	VBN
cord-263699-gosqpg3k	144	35	,	,	,
cord-263699-gosqpg3k	144	36	to	to	TO
cord-263699-gosqpg3k	144	37	favor	favor	VB
cord-263699-gosqpg3k	144	38	the	the	DT
cord-263699-gosqpg3k	144	39	replication	replication	NN
cord-263699-gosqpg3k	144	40	of	of	IN
cord-263699-gosqpg3k	144	41	the	the	DT
cord-263699-gosqpg3k	144	42	viral	viral	JJ
cord-263699-gosqpg3k	144	43	RNA	RNA	NNP
cord-263699-gosqpg3k	144	44	and	and	CC
cord-263699-gosqpg3k	144	45	,	,	,
cord-263699-gosqpg3k	144	46	at	at	IN
cord-263699-gosqpg3k	144	47	the	the	DT
cord-263699-gosqpg3k	144	48	same	same	JJ
cord-263699-gosqpg3k	144	49	time	time	NN
cord-263699-gosqpg3k	144	50	,	,	,
cord-263699-gosqpg3k	144	51	induces	induce	VBZ
cord-263699-gosqpg3k	144	52	the	the	DT
cord-263699-gosqpg3k	144	53	release	release	NN
cord-263699-gosqpg3k	144	54	of	of	IN
cord-263699-gosqpg3k	144	55	ADRP	ADRP	NNP
cord-263699-gosqpg3k	144	56	from	from	IN
cord-263699-gosqpg3k	144	57	LDs	LDs	NNP
cord-263699-gosqpg3k	144	58	to	to	TO
cord-263699-gosqpg3k	144	59	favor	favor	VB
cord-263699-gosqpg3k	144	60	the	the	DT
cord-263699-gosqpg3k	144	61	morphogenesis	morphogenesis	NN
cord-263699-gosqpg3k	144	62	of	of	IN
cord-263699-gosqpg3k	144	63	the	the	DT
cord-263699-gosqpg3k	144	64	virus	virus	NN
cord-263699-gosqpg3k	144	65	particles	particle	NNS
cord-263699-gosqpg3k	144	66	.	.	.
cord-263699-gosqpg3k	145	1	Since	since	IN
cord-263699-gosqpg3k	145	2	BFA	BFA	NNP
cord-263699-gosqpg3k	145	3	treatment	treatment	NN
cord-263699-gosqpg3k	145	4	has	have	VBZ
cord-263699-gosqpg3k	145	5	also	also	RB
cord-263699-gosqpg3k	145	6	been	be	VBN
cord-263699-gosqpg3k	145	7	shown	show	VBN
cord-263699-gosqpg3k	145	8	to	to	TO
cord-263699-gosqpg3k	145	9	inhibit	inhibit	VB
cord-263699-gosqpg3k	145	10	the	the	DT
cord-263699-gosqpg3k	145	11	secretion	secretion	NN
cord-263699-gosqpg3k	145	12	of	of	IN
cord-263699-gosqpg3k	145	13	HCV	HCV	NNP
cord-263699-gosqpg3k	145	14	viral	viral	JJ
cord-263699-gosqpg3k	145	15	particles	particle	NNS
cord-263699-gosqpg3k	145	16	,	,	,
cord-263699-gosqpg3k	145	17	leading	lead	VBG
cord-263699-gosqpg3k	145	18	to	to	IN
cord-263699-gosqpg3k	145	19	their	-PRON-	PRP$
cord-263699-gosqpg3k	145	20	progressive	progressive	JJ
cord-263699-gosqpg3k	145	21	intracellular	intracellular	JJ
cord-263699-gosqpg3k	145	22	accumulation	accumulation	NN
cord-263699-gosqpg3k	145	23	within	within	IN
cord-263699-gosqpg3k	145	24	the	the	DT
cord-263699-gosqpg3k	145	25	ER	ER	NNP
cord-263699-gosqpg3k	145	26	[	[	-LRB-
cord-263699-gosqpg3k	145	27	94	94	CD
cord-263699-gosqpg3k	145	28	]	]	-RRB-
cord-263699-gosqpg3k	145	29	,	,	,
cord-263699-gosqpg3k	145	30	it	-PRON-	PRP
cord-263699-gosqpg3k	145	31	seems	seem	VBZ
cord-263699-gosqpg3k	145	32	that	that	IN
cord-263699-gosqpg3k	145	33	GBF1	GBF1	NNP
cord-263699-gosqpg3k	145	34	is	be	VBZ
cord-263699-gosqpg3k	145	35	important	important	JJ
cord-263699-gosqpg3k	145	36	for	for	IN
cord-263699-gosqpg3k	145	37	both	both	CC
cord-263699-gosqpg3k	145	38	the	the	DT
cord-263699-gosqpg3k	145	39	assembly	assembly	NN
cord-263699-gosqpg3k	145	40	and	and	CC
cord-263699-gosqpg3k	145	41	exit	exit	NN
cord-263699-gosqpg3k	145	42	of	of	IN
cord-263699-gosqpg3k	145	43	the	the	DT
cord-263699-gosqpg3k	145	44	newly	newly	RB
cord-263699-gosqpg3k	145	45	formed	form	VBN
cord-263699-gosqpg3k	145	46	HCV	HCV	NNP
cord-263699-gosqpg3k	145	47	virions	virion	NNS
cord-263699-gosqpg3k	145	48	.	.	.
cord-263699-gosqpg3k	146	1	Similar	similar	JJ
cord-263699-gosqpg3k	146	2	to	to	IN
cord-263699-gosqpg3k	146	3	Arf1	Arf1	NNP
cord-263699-gosqpg3k	146	4	,	,	,
cord-263699-gosqpg3k	146	5	the	the	DT
cord-263699-gosqpg3k	146	6	simultaneous	simultaneous	JJ
cord-263699-gosqpg3k	146	7	depletion	depletion	NN
cord-263699-gosqpg3k	146	8	of	of	IN
cord-263699-gosqpg3k	146	9	Arf4	Arf4	NNP
cord-263699-gosqpg3k	146	10	and	and	CC
cord-263699-gosqpg3k	146	11	Arf5	Arf5	NNP
cord-263699-gosqpg3k	146	12	,	,	,
cord-263699-gosqpg3k	146	13	in	in	IN
cord-263699-gosqpg3k	146	14	which	which	WDT
cord-263699-gosqpg3k	146	15	the	the	DT
cord-263699-gosqpg3k	146	16	activation	activation	NN
cord-263699-gosqpg3k	146	17	also	also	RB
cord-263699-gosqpg3k	146	18	depends	depend	VBZ
cord-263699-gosqpg3k	146	19	on	on	IN
cord-263699-gosqpg3k	146	20	GBF1	GBF1	NNP
cord-263699-gosqpg3k	146	21	,	,	,
cord-263699-gosqpg3k	146	22	has	have	VBZ
cord-263699-gosqpg3k	146	23	been	be	VBN
cord-263699-gosqpg3k	146	24	reported	report	VBN
cord-263699-gosqpg3k	146	25	to	to	TO
cord-263699-gosqpg3k	146	26	reduce	reduce	VB
cord-263699-gosqpg3k	146	27	the	the	DT
cord-263699-gosqpg3k	146	28	RNA	RNA	NNP
cord-263699-gosqpg3k	146	29	replication	replication	NN
cord-263699-gosqpg3k	146	30	of	of	IN
cord-263699-gosqpg3k	146	31	HCV	HCV	NNP
cord-263699-gosqpg3k	146	32	probably	probably	RB
cord-263699-gosqpg3k	146	33	through	through	IN
cord-263699-gosqpg3k	146	34	affecting	affect	VBG
cord-263699-gosqpg3k	146	35	the	the	DT
cord-263699-gosqpg3k	146	36	morphology	morphology	NN
cord-263699-gosqpg3k	146	37	of	of	IN
cord-263699-gosqpg3k	146	38	LD	LD	NNP
cord-263699-gosqpg3k	146	39	but	but	CC
cord-263699-gosqpg3k	146	40	not	not	RB
cord-263699-gosqpg3k	146	41	the	the	DT
cord-263699-gosqpg3k	146	42	secretion	secretion	NN
cord-263699-gosqpg3k	146	43	pathway	pathway	NN
cord-263699-gosqpg3k	146	44	[	[	-LRB-
cord-263699-gosqpg3k	146	45	51	51	CD
cord-263699-gosqpg3k	146	46	,	,	,
cord-263699-gosqpg3k	146	47	91	91	CD
cord-263699-gosqpg3k	146	48	]	]	-RRB-
cord-263699-gosqpg3k	146	49	.	.	.
cord-263699-gosqpg3k	147	1	Altogether	altogether	RB
cord-263699-gosqpg3k	147	2	,	,	,
cord-263699-gosqpg3k	147	3	these	these	DT
cord-263699-gosqpg3k	147	4	results	result	NNS
cord-263699-gosqpg3k	147	5	suggest	suggest	VBP
cord-263699-gosqpg3k	147	6	that	that	IN
cord-263699-gosqpg3k	147	7	the	the	DT
cord-263699-gosqpg3k	147	8	role	role	NN
cord-263699-gosqpg3k	147	9	of	of	IN
cord-263699-gosqpg3k	147	10	GBF1	GBF1	NNP
cord-263699-gosqpg3k	147	11	is	be	VBZ
cord-263699-gosqpg3k	147	12	not	not	RB
cord-263699-gosqpg3k	147	13	restricted	restrict	VBN
cord-263699-gosqpg3k	147	14	to	to	TO
cord-263699-gosqpg3k	147	15	maintain	maintain	VB
cord-263699-gosqpg3k	147	16	a	a	DT
cord-263699-gosqpg3k	147	17	single	single	JJ
cord-263699-gosqpg3k	147	18	type	type	NN
cord-263699-gosqpg3k	147	19	of	of	IN
cord-263699-gosqpg3k	147	20	transport	transport	NN
cord-263699-gosqpg3k	147	21	but	but	CC
cord-263699-gosqpg3k	147	22	rather	rather	RB
cord-263699-gosqpg3k	147	23	to	to	TO
cord-263699-gosqpg3k	147	24	coordinate	coordinate	VB
cord-263699-gosqpg3k	147	25	different	different	JJ
cord-263699-gosqpg3k	147	26	transport	transport	NN
cord-263699-gosqpg3k	147	27	pathways	pathway	NNS
cord-263699-gosqpg3k	147	28	that	that	WDT
cord-263699-gosqpg3k	147	29	promote	promote	VBP
cord-263699-gosqpg3k	147	30	the	the	DT
cord-263699-gosqpg3k	147	31	infection	infection	NN
cord-263699-gosqpg3k	147	32	of	of	IN
cord-263699-gosqpg3k	147	33	HCV	HCV	NNP
cord-263699-gosqpg3k	147	34	.	.	.
cord-263699-gosqpg3k	148	1	Moreover	moreover	RB
cord-263699-gosqpg3k	148	2	,	,	,
cord-263699-gosqpg3k	148	3	they	-PRON-	PRP
cord-263699-gosqpg3k	148	4	also	also	RB
cord-263699-gosqpg3k	148	5	indicate	indicate	VBP
cord-263699-gosqpg3k	148	6	that	that	IN
cord-263699-gosqpg3k	148	7	the	the	DT
cord-263699-gosqpg3k	148	8	role	role	NN
cord-263699-gosqpg3k	148	9	of	of	IN
cord-263699-gosqpg3k	148	10	GBF1	GBF1	NNP
cord-263699-gosqpg3k	148	11	in	in	IN
cord-263699-gosqpg3k	148	12	the	the	DT
cord-263699-gosqpg3k	148	13	LD	LD	NNP
cord-263699-gosqpg3k	148	14	transport	transport	NN
cord-263699-gosqpg3k	148	15	,	,	,
cord-263699-gosqpg3k	148	16	but	but	CC
cord-263699-gosqpg3k	148	17	not	not	RB
cord-263699-gosqpg3k	148	18	in	in	IN
cord-263699-gosqpg3k	148	19	the	the	DT
cord-263699-gosqpg3k	148	20	secretory	secretory	JJ
cord-263699-gosqpg3k	148	21	pathway	pathway	NN
cord-263699-gosqpg3k	148	22	,	,	,
cord-263699-gosqpg3k	148	23	is	be	VBZ
cord-263699-gosqpg3k	148	24	important	important	JJ
cord-263699-gosqpg3k	148	25	for	for	IN
cord-263699-gosqpg3k	148	26	HCV	HCV	NNP
cord-263699-gosqpg3k	148	27	infection	infection	NN
cord-263699-gosqpg3k	148	28	.	.	.
cord-263699-gosqpg3k	149	1	In	in	IN
cord-263699-gosqpg3k	149	2	agreement	agreement	NN
cord-263699-gosqpg3k	149	3	,	,	,
cord-263699-gosqpg3k	149	4	several	several	JJ
cord-263699-gosqpg3k	149	5	works	work	NNS
cord-263699-gosqpg3k	149	6	have	have	VBP
cord-263699-gosqpg3k	149	7	reported	report	VBN
cord-263699-gosqpg3k	149	8	that	that	IN
cord-263699-gosqpg3k	149	9	HCV	HCV	NNP
cord-263699-gosqpg3k	149	10	replication	replication	NN
cord-263699-gosqpg3k	149	11	can	can	MD
cord-263699-gosqpg3k	149	12	be	be	VB
cord-263699-gosqpg3k	149	13	completely	completely	RB
cord-263699-gosqpg3k	149	14	inhibited	inhibit	VBN
cord-263699-gosqpg3k	149	15	at	at	IN
cord-263699-gosqpg3k	149	16	BFA	BFA	NNP
cord-263699-gosqpg3k	149	17	concentrations	concentration	NNS
cord-263699-gosqpg3k	149	18	that	that	WDT
cord-263699-gosqpg3k	149	19	do	do	VBP
cord-263699-gosqpg3k	149	20	not	not	RB
cord-263699-gosqpg3k	149	21	affect	affect	VB
cord-263699-gosqpg3k	149	22	the	the	DT
cord-263699-gosqpg3k	149	23	secretion	secretion	NN
cord-263699-gosqpg3k	149	24	of	of	IN
cord-263699-gosqpg3k	149	25	proteins	protein	NNS
cord-263699-gosqpg3k	149	26	[	[	-LRB-
cord-263699-gosqpg3k	149	27	54	54	CD
cord-263699-gosqpg3k	149	28	,	,	,
cord-263699-gosqpg3k	149	29	55	55	CD
cord-263699-gosqpg3k	149	30	,	,	,
cord-263699-gosqpg3k	149	31	95	95	CD
cord-263699-gosqpg3k	149	32	]	]	-RRB-
cord-263699-gosqpg3k	149	33	.	.	.
cord-263699-gosqpg3k	150	1	In	in	IN
cord-263699-gosqpg3k	150	2	addition	addition	NN
cord-263699-gosqpg3k	150	3	to	to	IN
cord-263699-gosqpg3k	150	4	the	the	DT
cord-263699-gosqpg3k	150	5	role	role	NN
cord-263699-gosqpg3k	150	6	of	of	IN
cord-263699-gosqpg3k	150	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	150	8	in	in	IN
cord-263699-gosqpg3k	150	9	the	the	DT
cord-263699-gosqpg3k	150	10	transport	transport	NN
cord-263699-gosqpg3k	150	11	of	of	IN
cord-263699-gosqpg3k	150	12	cellular	cellular	JJ
cord-263699-gosqpg3k	150	13	and	and	CC
cord-263699-gosqpg3k	150	14	viral	viral	JJ
cord-263699-gosqpg3k	150	15	proteins	protein	NNS
cord-263699-gosqpg3k	150	16	relevant	relevant	JJ
cord-263699-gosqpg3k	150	17	for	for	IN
cord-263699-gosqpg3k	150	18	RNA	RNA	NNP
cord-263699-gosqpg3k	150	19	replication	replication	NN
cord-263699-gosqpg3k	150	20	and	and	CC
cord-263699-gosqpg3k	150	21	viral	viral	JJ
cord-263699-gosqpg3k	150	22	assembly	assembly	NN
cord-263699-gosqpg3k	150	23	,	,	,
cord-263699-gosqpg3k	150	24	it	-PRON-	PRP
cord-263699-gosqpg3k	150	25	has	have	VBZ
cord-263699-gosqpg3k	150	26	also	also	RB
cord-263699-gosqpg3k	150	27	been	be	VBN
cord-263699-gosqpg3k	150	28	observed	observe	VBN
cord-263699-gosqpg3k	150	29	that	that	IN
cord-263699-gosqpg3k	150	30	this	this	DT
cord-263699-gosqpg3k	150	31	factor	factor	NN
cord-263699-gosqpg3k	150	32	can	can	MD
cord-263699-gosqpg3k	150	33	regulate	regulate	VB
cord-263699-gosqpg3k	150	34	the	the	DT
cord-263699-gosqpg3k	150	35	lipid	lipid	NN
cord-263699-gosqpg3k	150	36	composition	composition	NN
cord-263699-gosqpg3k	150	37	of	of	IN
cord-263699-gosqpg3k	150	38	the	the	DT
cord-263699-gosqpg3k	150	39	membranous	membranous	JJ
cord-263699-gosqpg3k	150	40	web	web	NN
cord-263699-gosqpg3k	150	41	induced	induce	VBN
cord-263699-gosqpg3k	150	42	by	by	IN
cord-263699-gosqpg3k	150	43	HCV	HCV	NNP
cord-263699-gosqpg3k	150	44	.	.	.
cord-263699-gosqpg3k	151	1	Inhibition	inhibition	NN
cord-263699-gosqpg3k	151	2	of	of	IN
cord-263699-gosqpg3k	151	3	GBF1	GBF1	NNP
cord-263699-gosqpg3k	151	4	activity	activity	NN
cord-263699-gosqpg3k	151	5	and	and	CC
cord-263699-gosqpg3k	151	6	Arf1	Arf1	NNP
cord-263699-gosqpg3k	151	7	activation	activation	NN
cord-263699-gosqpg3k	151	8	abolishes	abolish	VBZ
cord-263699-gosqpg3k	151	9	the	the	DT
cord-263699-gosqpg3k	151	10	accumulation	accumulation	NN
cord-263699-gosqpg3k	151	11	of	of	IN
cord-263699-gosqpg3k	152	1	phosphatidylinositol	phosphatidylinositol	JJ
cord-263699-gosqpg3k	152	2	4-phosphate	4-phosphate	CD
cord-263699-gosqpg3k	152	3	(	(	-LRB-
cord-263699-gosqpg3k	152	4	PI4P	PI4P	NNP
cord-263699-gosqpg3k	152	5	)	)	-RRB-
cord-263699-gosqpg3k	152	6	in	in	IN
cord-263699-gosqpg3k	152	7	the	the	DT
cord-263699-gosqpg3k	152	8	membranes	membrane	NNS
cord-263699-gosqpg3k	152	9	of	of	IN
cord-263699-gosqpg3k	152	10	the	the	DT
cord-263699-gosqpg3k	152	11	HCV	HCV	NNP
cord-263699-gosqpg3k	152	12	replication	replication	NN
cord-263699-gosqpg3k	152	13	complexes	complex	NNS
cord-263699-gosqpg3k	152	14	[	[	-LRB-
cord-263699-gosqpg3k	152	15	96	96	CD
cord-263699-gosqpg3k	152	16	]	]	-RRB-
cord-263699-gosqpg3k	152	17	,	,	,
cord-263699-gosqpg3k	152	18	a	a	DT
cord-263699-gosqpg3k	152	19	process	process	NN
cord-263699-gosqpg3k	152	20	that	that	WDT
cord-263699-gosqpg3k	152	21	has	have	VBZ
cord-263699-gosqpg3k	152	22	been	be	VBN
cord-263699-gosqpg3k	152	23	shown	show	VBN
cord-263699-gosqpg3k	152	24	to	to	TO
cord-263699-gosqpg3k	152	25	promote	promote	VB
cord-263699-gosqpg3k	152	26	the	the	DT
cord-263699-gosqpg3k	152	27	replication	replication	NN
cord-263699-gosqpg3k	152	28	of	of	IN
cord-263699-gosqpg3k	152	29	the	the	DT
cord-263699-gosqpg3k	152	30	viral	viral	JJ
cord-263699-gosqpg3k	152	31	RNA	RNA	NNP
cord-263699-gosqpg3k	152	32	.	.	.
cord-263699-gosqpg3k	153	1	Although	although	IN
cord-263699-gosqpg3k	153	2	it	-PRON-	PRP
cord-263699-gosqpg3k	153	3	is	be	VBZ
cord-263699-gosqpg3k	153	4	not	not	RB
cord-263699-gosqpg3k	153	5	clear	clear	JJ
cord-263699-gosqpg3k	153	6	how	how	WRB
cord-263699-gosqpg3k	153	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	153	8	and	and	CC
cord-263699-gosqpg3k	153	9	Arf1	Arf1	NNP
cord-263699-gosqpg3k	153	10	prompt	prompt	VB
cord-263699-gosqpg3k	153	11	the	the	DT
cord-263699-gosqpg3k	153	12	accumulation	accumulation	NN
cord-263699-gosqpg3k	153	13	of	of	IN
cord-263699-gosqpg3k	153	14	PI4P	PI4P	NNP
cord-263699-gosqpg3k	153	15	,	,	,
cord-263699-gosqpg3k	153	16	recent	recent	JJ
cord-263699-gosqpg3k	153	17	findings	finding	NNS
cord-263699-gosqpg3k	153	18	suggest	suggest	VBP
cord-263699-gosqpg3k	153	19	that	that	IN
cord-263699-gosqpg3k	153	20	these	these	DT
cord-263699-gosqpg3k	153	21	factors	factor	NNS
cord-263699-gosqpg3k	153	22	might	may	MD
cord-263699-gosqpg3k	153	23	induce	induce	VB
cord-263699-gosqpg3k	153	24	the	the	DT
cord-263699-gosqpg3k	153	25	transport	transport	NN
cord-263699-gosqpg3k	153	26	to	to	IN
cord-263699-gosqpg3k	153	27	the	the	DT
cord-263699-gosqpg3k	153	28	HCV	HCV	NNP
cord-263699-gosqpg3k	153	29	replication	replication	NN
cord-263699-gosqpg3k	153	30	sites	site	NNS
cord-263699-gosqpg3k	153	31	of	of	IN
cord-263699-gosqpg3k	153	32	the	the	DT
cord-263699-gosqpg3k	153	33	type	type	NN
cord-263699-gosqpg3k	153	34	III	iii	CD
cord-263699-gosqpg3k	153	35	phosphatidylinositol	phosphatidylinositol	NN
cord-263699-gosqpg3k	153	36	4-kinases	4-kinases	CD
cord-263699-gosqpg3k	153	37	α	α	NN
cord-263699-gosqpg3k	153	38	(	(	-LRB-
cord-263699-gosqpg3k	153	39	PI4KIIIα	PI4KIIIα	NNP
cord-263699-gosqpg3k	153	40	)	)	-RRB-
cord-263699-gosqpg3k	153	41	and	and	CC
cord-263699-gosqpg3k	153	42	β	β	FW
cord-263699-gosqpg3k	153	43	(	(	-LRB-
cord-263699-gosqpg3k	153	44	PI4KIIIβ	PI4KIIIβ	NNP
cord-263699-gosqpg3k	153	45	)	)	-RRB-
cord-263699-gosqpg3k	153	46	enzymes	enzyme	NNS
cord-263699-gosqpg3k	153	47	,	,	,
cord-263699-gosqpg3k	153	48	which	which	WDT
cord-263699-gosqpg3k	153	49	are	be	VBP
cord-263699-gosqpg3k	153	50	responsible	responsible	JJ
cord-263699-gosqpg3k	153	51	in	in	IN
cord-263699-gosqpg3k	153	52	the	the	DT
cord-263699-gosqpg3k	153	53	Golgi	Golgi	NNP
cord-263699-gosqpg3k	153	54	apparatus	apparatus	NN
cord-263699-gosqpg3k	153	55	for	for	IN
cord-263699-gosqpg3k	153	56	the	the	DT
cord-263699-gosqpg3k	153	57	generation	generation	NN
cord-263699-gosqpg3k	153	58	of	of	IN
cord-263699-gosqpg3k	153	59	PI4P.	PI4P.	NNP
cord-263699-gosqpg3k	154	1	Although	although	IN
cord-263699-gosqpg3k	154	2	the	the	DT
cord-263699-gosqpg3k	154	3	precise	precise	JJ
cord-263699-gosqpg3k	154	4	role	role	NN
cord-263699-gosqpg3k	154	5	of	of	IN
cord-263699-gosqpg3k	154	6	PI4P	PI4P	NNP
cord-263699-gosqpg3k	154	7	in	in	IN
cord-263699-gosqpg3k	154	8	HCV	HCV	NNP
cord-263699-gosqpg3k	154	9	replication	replication	NN
cord-263699-gosqpg3k	154	10	remains	remain	VBZ
cord-263699-gosqpg3k	154	11	unknown	unknown	JJ
cord-263699-gosqpg3k	154	12	,	,	,
cord-263699-gosqpg3k	154	13	it	-PRON-	PRP
cord-263699-gosqpg3k	154	14	has	have	VBZ
cord-263699-gosqpg3k	154	15	been	be	VBN
cord-263699-gosqpg3k	154	16	proposed	propose	VBN
cord-263699-gosqpg3k	154	17	that	that	IN
cord-263699-gosqpg3k	154	18	these	these	DT
cord-263699-gosqpg3k	154	19	lipids	lipid	NNS
cord-263699-gosqpg3k	154	20	might	may	MD
cord-263699-gosqpg3k	154	21	be	be	VB
cord-263699-gosqpg3k	154	22	important	important	JJ
cord-263699-gosqpg3k	154	23	to	to	TO
cord-263699-gosqpg3k	154	24	generate	generate	VB
cord-263699-gosqpg3k	154	25	membranes	membrane	NNS
cord-263699-gosqpg3k	154	26	sites	site	NNS
cord-263699-gosqpg3k	154	27	that	that	WDT
cord-263699-gosqpg3k	154	28	permit	permit	VBP
cord-263699-gosqpg3k	154	29	the	the	DT
cord-263699-gosqpg3k	154	30	association	association	NN
cord-263699-gosqpg3k	154	31	of	of	IN
cord-263699-gosqpg3k	154	32	proteins	protein	NNS
cord-263699-gosqpg3k	154	33	to	to	IN
cord-263699-gosqpg3k	154	34	the	the	DT
cord-263699-gosqpg3k	154	35	replication	replication	NN
cord-263699-gosqpg3k	154	36	complex	complex	NN
cord-263699-gosqpg3k	154	37	of	of	IN
cord-263699-gosqpg3k	154	38	HCV	HCV	NNP
cord-263699-gosqpg3k	154	39	,	,	,
cord-263699-gosqpg3k	154	40	but	but	CC
cord-263699-gosqpg3k	154	41	it	-PRON-	PRP
cord-263699-gosqpg3k	154	42	could	could	MD
cord-263699-gosqpg3k	154	43	also	also	RB
cord-263699-gosqpg3k	154	44	impact	impact	VB
cord-263699-gosqpg3k	154	45	the	the	DT
cord-263699-gosqpg3k	154	46	organization	organization	NN
cord-263699-gosqpg3k	154	47	and	and	CC
cord-263699-gosqpg3k	154	48	kinetics	kinetic	NNS
cord-263699-gosqpg3k	154	49	of	of	IN
cord-263699-gosqpg3k	154	50	the	the	DT
cord-263699-gosqpg3k	154	51	transport	transport	NN
cord-263699-gosqpg3k	154	52	pathways	pathway	NNS
cord-263699-gosqpg3k	154	53	modulated	modulate	VBN
cord-263699-gosqpg3k	154	54	by	by	IN
cord-263699-gosqpg3k	154	55	HCV	HCV	NNP
cord-263699-gosqpg3k	154	56	[	[	-LRB-
cord-263699-gosqpg3k	154	57	56	56	CD
cord-263699-gosqpg3k	154	58	,	,	,
cord-263699-gosqpg3k	154	59	62	62	CD
cord-263699-gosqpg3k	154	60	,	,	,
cord-263699-gosqpg3k	154	61	97	97	CD
cord-263699-gosqpg3k	154	62	]	]	-RRB-
cord-263699-gosqpg3k	154	63	.	.	.
cord-263699-gosqpg3k	155	1	In	in	IN
cord-263699-gosqpg3k	155	2	a	a	DT
cord-263699-gosqpg3k	155	3	mechanism	mechanism	NN
cord-263699-gosqpg3k	155	4	apparently	apparently	RB
cord-263699-gosqpg3k	155	5	different	different	JJ
cord-263699-gosqpg3k	155	6	from	from	IN
cord-263699-gosqpg3k	155	7	the	the	DT
cord-263699-gosqpg3k	155	8	regulation	regulation	NN
cord-263699-gosqpg3k	155	9	of	of	IN
cord-263699-gosqpg3k	155	10	protein	protein	NN
cord-263699-gosqpg3k	155	11	traffic	traffic	NN
cord-263699-gosqpg3k	155	12	,	,	,
cord-263699-gosqpg3k	155	13	it	-PRON-	PRP
cord-263699-gosqpg3k	155	14	has	have	VBZ
cord-263699-gosqpg3k	155	15	been	be	VBN
cord-263699-gosqpg3k	155	16	found	find	VBN
cord-263699-gosqpg3k	155	17	that	that	IN
cord-263699-gosqpg3k	155	18	GBF1	GBF1	NNP
cord-263699-gosqpg3k	155	19	might	may	MD
cord-263699-gosqpg3k	155	20	also	also	RB
cord-263699-gosqpg3k	155	21	modulate	modulate	VB
cord-263699-gosqpg3k	155	22	the	the	DT
cord-263699-gosqpg3k	155	23	processing	processing	NN
cord-263699-gosqpg3k	155	24	of	of	IN
cord-263699-gosqpg3k	155	25	the	the	DT
cord-263699-gosqpg3k	155	26	HCV	HCV	NNP
cord-263699-gosqpg3k	155	27	polyprotein	polyprotein	NN
cord-263699-gosqpg3k	155	28	by	by	IN
cord-263699-gosqpg3k	155	29	regulating	regulate	VBG
cord-263699-gosqpg3k	155	30	the	the	DT
cord-263699-gosqpg3k	155	31	protease	protease	NN
cord-263699-gosqpg3k	155	32	activity	activity	NN
cord-263699-gosqpg3k	155	33	of	of	IN
cord-263699-gosqpg3k	155	34	the	the	DT
cord-263699-gosqpg3k	155	35	NS3-NS4A	NS3-NS4A	NNP
cord-263699-gosqpg3k	155	36	complex	complex	JJ
cord-263699-gosqpg3k	155	37	;	;	:
cord-263699-gosqpg3k	155	38	this	this	DT
cord-263699-gosqpg3k	155	39	regulation	regulation	NN
cord-263699-gosqpg3k	155	40	process	process	NN
cord-263699-gosqpg3k	155	41	requires	require	VBZ
cord-263699-gosqpg3k	155	42	the	the	DT
cord-263699-gosqpg3k	155	43	interaction	interaction	NN
cord-263699-gosqpg3k	155	44	between	between	IN
cord-263699-gosqpg3k	155	45	the	the	DT
cord-263699-gosqpg3k	155	46	Sec7	Sec7	NNP
cord-263699-gosqpg3k	155	47	domain	domain	NN
cord-263699-gosqpg3k	155	48	of	of	IN
cord-263699-gosqpg3k	155	49	GBF1	GBF1	NNP
cord-263699-gosqpg3k	155	50	and	and	CC
cord-263699-gosqpg3k	155	51	the	the	DT
cord-263699-gosqpg3k	155	52	protease	protease	NN
cord-263699-gosqpg3k	155	53	domain	domain	NN
cord-263699-gosqpg3k	155	54	of	of	IN
cord-263699-gosqpg3k	155	55	NS3	NS3	NNP
cord-263699-gosqpg3k	155	56	.	.	.
cord-263699-gosqpg3k	156	1	Moreover	moreover	RB
cord-263699-gosqpg3k	156	2	,	,	,
cord-263699-gosqpg3k	156	3	the	the	DT
cord-263699-gosqpg3k	156	4	protease	protease	NN
cord-263699-gosqpg3k	156	5	activity	activity	NN
cord-263699-gosqpg3k	156	6	of	of	IN
cord-263699-gosqpg3k	156	7	the	the	DT
cord-263699-gosqpg3k	156	8	NS3-NS4A	NS3-NS4A	NNP
cord-263699-gosqpg3k	156	9	complex	complex	NN
cord-263699-gosqpg3k	156	10	has	have	VBZ
cord-263699-gosqpg3k	156	11	been	be	VBN
cord-263699-gosqpg3k	156	12	shown	show	VBN
cord-263699-gosqpg3k	156	13	to	to	TO
cord-263699-gosqpg3k	156	14	depend	depend	VB
cord-263699-gosqpg3k	156	15	on	on	IN
cord-263699-gosqpg3k	156	16	the	the	DT
cord-263699-gosqpg3k	156	17	catalytic	catalytic	JJ
cord-263699-gosqpg3k	156	18	activity	activity	NN
cord-263699-gosqpg3k	156	19	of	of	IN
cord-263699-gosqpg3k	156	20	GBF1	GBF1	NNP
cord-263699-gosqpg3k	156	21	[	[	-LRB-
cord-263699-gosqpg3k	156	22	98	98	CD
cord-263699-gosqpg3k	156	23	]	]	-RRB-
cord-263699-gosqpg3k	156	24	.	.	.
cord-263699-gosqpg3k	157	1	The	the	DT
cord-263699-gosqpg3k	157	2	genus	genus	NN
cord-263699-gosqpg3k	157	3	Enterovirus	enterovirus	NN
cord-263699-gosqpg3k	157	4	(	(	-LRB-
cord-263699-gosqpg3k	157	5	EV	ev	NN
cord-263699-gosqpg3k	157	6	)	)	-RRB-
cord-263699-gosqpg3k	157	7	includes	include	VBZ
cord-263699-gosqpg3k	157	8	a	a	DT
cord-263699-gosqpg3k	157	9	collection	collection	NN
cord-263699-gosqpg3k	157	10	of	of	IN
cord-263699-gosqpg3k	157	11	small	small	JJ
cord-263699-gosqpg3k	157	12	non	non	NNS
cord-263699-gosqpg3k	157	13	-	-	JJ
cord-263699-gosqpg3k	157	14	enveloped	enveloped	JJ
cord-263699-gosqpg3k	157	15	viruses	virus	NNS
cord-263699-gosqpg3k	157	16	with	with	IN
cord-263699-gosqpg3k	157	17	a	a	DT
cord-263699-gosqpg3k	157	18	small	small	JJ
cord-263699-gosqpg3k	157	19	positive	positive	JJ
cord-263699-gosqpg3k	157	20	-	-	HYPH
cord-263699-gosqpg3k	157	21	sense	sense	NN
cord-263699-gosqpg3k	157	22	single	single	JJ
cord-263699-gosqpg3k	157	23	-	-	HYPH
cord-263699-gosqpg3k	157	24	stranded	strand	VBN
cord-263699-gosqpg3k	157	25	RNA	RNA	NNP
cord-263699-gosqpg3k	157	26	genome	genome	NN
cord-263699-gosqpg3k	157	27	.	.	.
cord-263699-gosqpg3k	158	1	These	these	DT
cord-263699-gosqpg3k	158	2	viruses	virus	NNS
cord-263699-gosqpg3k	158	3	have	have	VBP
cord-263699-gosqpg3k	158	4	been	be	VBN
cord-263699-gosqpg3k	158	5	classified	classify	VBN
cord-263699-gosqpg3k	158	6	into	into	IN
cord-263699-gosqpg3k	158	7	15	15	CD
cord-263699-gosqpg3k	158	8	serologically	serologically	RB
cord-263699-gosqpg3k	158	9	distinct	distinct	JJ
cord-263699-gosqpg3k	158	10	groups	group	NNS
cord-263699-gosqpg3k	158	11	,	,	,
cord-263699-gosqpg3k	158	12	comprising	comprise	VBG
cord-263699-gosqpg3k	158	13	12	12	CD
cord-263699-gosqpg3k	158	14	groups	group	NNS
cord-263699-gosqpg3k	158	15	of	of	IN
cord-263699-gosqpg3k	158	16	enterovirus	enterovirus	NN
cord-263699-gosqpg3k	158	17	(	(	-LRB-
cord-263699-gosqpg3k	158	18	EV	ev	NN
cord-263699-gosqpg3k	158	19	-	-	HYPH
cord-263699-gosqpg3k	158	20	A	a	NN
cord-263699-gosqpg3k	158	21	to	to	IN
cord-263699-gosqpg3k	158	22	L	L	NNP
cord-263699-gosqpg3k	158	23	)	)	-RRB-
cord-263699-gosqpg3k	158	24	,	,	,
cord-263699-gosqpg3k	158	25	and	and	CC
cord-263699-gosqpg3k	158	26	three	three	CD
cord-263699-gosqpg3k	158	27	groups	group	NNS
cord-263699-gosqpg3k	158	28	of	of	IN
cord-263699-gosqpg3k	158	29	rhinovirus	rhinovirus	NN
cord-263699-gosqpg3k	158	30	(	(	-LRB-
cord-263699-gosqpg3k	158	31	RV	rv	NN
cord-263699-gosqpg3k	158	32	)	)	-RRB-
cord-263699-gosqpg3k	158	33	(	(	-LRB-
cord-263699-gosqpg3k	158	34	RV	rv	NN
cord-263699-gosqpg3k	158	35	-	-	HYPH
cord-263699-gosqpg3k	158	36	A	a	NN
cord-263699-gosqpg3k	158	37	to	to	IN
cord-263699-gosqpg3k	158	38	C	C	NNP
cord-263699-gosqpg3k	158	39	)	)	-RRB-
cord-263699-gosqpg3k	158	40	.	.	.
cord-263699-gosqpg3k	159	1	The	the	DT
cord-263699-gosqpg3k	159	2	replication	replication	NN
cord-263699-gosqpg3k	159	3	cycle	cycle	NN
cord-263699-gosqpg3k	159	4	of	of	IN
cord-263699-gosqpg3k	159	5	EV	ev	NN
cord-263699-gosqpg3k	159	6	starts	start	VBZ
cord-263699-gosqpg3k	159	7	with	with	IN
cord-263699-gosqpg3k	159	8	the	the	DT
cord-263699-gosqpg3k	159	9	attachment	attachment	NN
cord-263699-gosqpg3k	159	10	of	of	IN
cord-263699-gosqpg3k	159	11	the	the	DT
cord-263699-gosqpg3k	159	12	virus	virus	NN
cord-263699-gosqpg3k	159	13	to	to	IN
cord-263699-gosqpg3k	159	14	specific	specific	JJ
cord-263699-gosqpg3k	159	15	cell	cell	NN
cord-263699-gosqpg3k	159	16	host	host	NN
cord-263699-gosqpg3k	159	17	receptors	receptor	NNS
cord-263699-gosqpg3k	159	18	.	.	.
cord-263699-gosqpg3k	160	1	After	after	IN
cord-263699-gosqpg3k	160	2	virus	virus	NN
cord-263699-gosqpg3k	160	3	internalization	internalization	NN
cord-263699-gosqpg3k	160	4	,	,	,
cord-263699-gosqpg3k	160	5	the	the	DT
cord-263699-gosqpg3k	160	6	viral	viral	JJ
cord-263699-gosqpg3k	160	7	genome	genome	NN
cord-263699-gosqpg3k	160	8	is	be	VBZ
cord-263699-gosqpg3k	160	9	released	release	VBN
cord-263699-gosqpg3k	160	10	into	into	IN
cord-263699-gosqpg3k	160	11	the	the	DT
cord-263699-gosqpg3k	160	12	cytoplasm	cytoplasm	NN
cord-263699-gosqpg3k	160	13	to	to	TO
cord-263699-gosqpg3k	160	14	direct	direct	VB
cord-263699-gosqpg3k	160	15	the	the	DT
cord-263699-gosqpg3k	160	16	synthesis	synthesis	NN
cord-263699-gosqpg3k	160	17	of	of	IN
cord-263699-gosqpg3k	160	18	a	a	DT
cord-263699-gosqpg3k	160	19	single	single	JJ
cord-263699-gosqpg3k	160	20	polyprotein	polyprotein	NN
cord-263699-gosqpg3k	160	21	,	,	,
cord-263699-gosqpg3k	160	22	which	which	WDT
cord-263699-gosqpg3k	160	23	is	be	VBZ
cord-263699-gosqpg3k	160	24	auto	auto	NN
cord-263699-gosqpg3k	160	25	-	-	HYPH
cord-263699-gosqpg3k	160	26	processed	process	VBN
cord-263699-gosqpg3k	160	27	by	by	IN
cord-263699-gosqpg3k	160	28	viral	viral	JJ
cord-263699-gosqpg3k	160	29	proteases	protease	NNS
cord-263699-gosqpg3k	160	30	2A	2a	CD
cord-263699-gosqpg3k	160	31	and	and	CC
cord-263699-gosqpg3k	160	32	3C	3c	NN
cord-263699-gosqpg3k	160	33	to	to	TO
cord-263699-gosqpg3k	160	34	produce	produce	VB
cord-263699-gosqpg3k	160	35	three	three	CD
cord-263699-gosqpg3k	160	36	structural	structural	JJ
cord-263699-gosqpg3k	160	37	proteins	protein	NNS
cord-263699-gosqpg3k	160	38	(	(	-LRB-
cord-263699-gosqpg3k	160	39	VP0	VP0	NNP
cord-263699-gosqpg3k	160	40	,	,	,
cord-263699-gosqpg3k	160	41	VP1	VP1	NNP
cord-263699-gosqpg3k	160	42	,	,	,
cord-263699-gosqpg3k	160	43	and	and	CC
cord-263699-gosqpg3k	160	44	VP3	VP3	NNP
cord-263699-gosqpg3k	160	45	)	)	-RRB-
cord-263699-gosqpg3k	160	46	and	and	CC
cord-263699-gosqpg3k	160	47	seven	seven	CD
cord-263699-gosqpg3k	160	48	nonstructural	nonstructural	JJ
cord-263699-gosqpg3k	160	49	proteins	protein	NNS
cord-263699-gosqpg3k	160	50	(	(	-LRB-
cord-263699-gosqpg3k	160	51	2A-2C	2a-2c	CD
cord-263699-gosqpg3k	160	52	and	and	CC
cord-263699-gosqpg3k	160	53	3A-3D	3a-3d	CD
cord-263699-gosqpg3k	160	54	)	)	-RRB-
cord-263699-gosqpg3k	160	55	,	,	,
cord-263699-gosqpg3k	160	56	as	as	RB
cord-263699-gosqpg3k	160	57	well	well	RB
cord-263699-gosqpg3k	160	58	as	as	IN
cord-263699-gosqpg3k	160	59	some	some	DT
cord-263699-gosqpg3k	160	60	stable	stable	JJ
cord-263699-gosqpg3k	160	61	protein	protein	NN
cord-263699-gosqpg3k	160	62	precursors	precursor	NNS
cord-263699-gosqpg3k	160	63	(	(	-LRB-
cord-263699-gosqpg3k	160	64	2BC	2BC	NNP
cord-263699-gosqpg3k	160	65	,	,	,
cord-263699-gosqpg3k	160	66	3AB	3AB	NNP
cord-263699-gosqpg3k	160	67	,	,	,
cord-263699-gosqpg3k	160	68	and	and	CC
cord-263699-gosqpg3k	160	69	3CD	3cd	NN
cord-263699-gosqpg3k	160	70	)	)	-RRB-
cord-263699-gosqpg3k	160	71	that	that	WDT
cord-263699-gosqpg3k	160	72	can	can	MD
cord-263699-gosqpg3k	160	73	also	also	RB
cord-263699-gosqpg3k	160	74	participate	participate	VB
cord-263699-gosqpg3k	160	75	in	in	IN
cord-263699-gosqpg3k	160	76	the	the	DT
cord-263699-gosqpg3k	160	77	replication	replication	NN
cord-263699-gosqpg3k	160	78	cycle	cycle	NN
cord-263699-gosqpg3k	160	79	.	.	.
cord-263699-gosqpg3k	161	1	As	as	IN
cord-263699-gosqpg3k	161	2	the	the	DT
cord-263699-gosqpg3k	161	3	infection	infection	NN
cord-263699-gosqpg3k	161	4	progresses	progress	VBZ
cord-263699-gosqpg3k	161	5	,	,	,
cord-263699-gosqpg3k	161	6	EV	EV	NNP
cord-263699-gosqpg3k	161	7	promotes	promote	VBZ
cord-263699-gosqpg3k	161	8	the	the	DT
cord-263699-gosqpg3k	161	9	creation	creation	NN
cord-263699-gosqpg3k	161	10	of	of	IN
cord-263699-gosqpg3k	161	11	viral	viral	JJ
cord-263699-gosqpg3k	161	12	cytoplasmic	cytoplasmic	JJ
cord-263699-gosqpg3k	161	13	replication	replication	NN
cord-263699-gosqpg3k	161	14	complexes	complex	NNS
cord-263699-gosqpg3k	161	15	formed	form	VBN
cord-263699-gosqpg3k	161	16	by	by	IN
cord-263699-gosqpg3k	161	17	clusters	cluster	NNS
cord-263699-gosqpg3k	161	18	of	of	IN
cord-263699-gosqpg3k	161	19	tightly	tightly	RB
cord-263699-gosqpg3k	161	20	associated	associate	VBN
cord-263699-gosqpg3k	161	21	vesicles	vesicle	NNS
cord-263699-gosqpg3k	161	22	of	of	IN
cord-263699-gosqpg3k	161	23	heterogeneous	heterogeneous	JJ
cord-263699-gosqpg3k	161	24	size	size	NN
cord-263699-gosqpg3k	161	25	,	,	,
cord-263699-gosqpg3k	161	26	where	where	WRB
cord-263699-gosqpg3k	161	27	the	the	DT
cord-263699-gosqpg3k	161	28	viral	viral	JJ
cord-263699-gosqpg3k	161	29	RdRp	RdRp	NNP
cord-263699-gosqpg3k	161	30	3D	3D	NNP
cord-263699-gosqpg3k	161	31	protein	protein	NN
cord-263699-gosqpg3k	161	32	directs	direct	VBZ
cord-263699-gosqpg3k	161	33	the	the	DT
cord-263699-gosqpg3k	161	34	replication	replication	NN
cord-263699-gosqpg3k	161	35	of	of	IN
cord-263699-gosqpg3k	161	36	the	the	DT
cord-263699-gosqpg3k	161	37	genomic	genomic	JJ
cord-263699-gosqpg3k	161	38	RNA	RNA	NNP
cord-263699-gosqpg3k	161	39	.	.	.
cord-263699-gosqpg3k	162	1	The	the	DT
cord-263699-gosqpg3k	162	2	novel	novel	JJ
cord-263699-gosqpg3k	162	3	genomic	genomic	NN
cord-263699-gosqpg3k	162	4	RNA	RNA	NNP
cord-263699-gosqpg3k	162	5	then	then	RB
cord-263699-gosqpg3k	162	6	is	be	VBZ
cord-263699-gosqpg3k	162	7	either	either	CC
cord-263699-gosqpg3k	162	8	translated	translate	VBN
cord-263699-gosqpg3k	162	9	or	or	CC
cord-263699-gosqpg3k	162	10	packaged	package	VBN
cord-263699-gosqpg3k	162	11	into	into	IN
cord-263699-gosqpg3k	162	12	preassembled	preassembled	JJ
cord-263699-gosqpg3k	162	13	procapsids	procapsid	NNS
cord-263699-gosqpg3k	162	14	(	(	-LRB-
cord-263699-gosqpg3k	162	15	composed	compose	VBN
cord-263699-gosqpg3k	162	16	of	of	IN
cord-263699-gosqpg3k	162	17	VP0	VP0	NNP
cord-263699-gosqpg3k	162	18	,	,	,
cord-263699-gosqpg3k	162	19	VP1	vp1	NN
cord-263699-gosqpg3k	162	20	,	,	,
cord-263699-gosqpg3k	162	21	and	and	CC
cord-263699-gosqpg3k	162	22	VP3	VP3	NNP
cord-263699-gosqpg3k	162	23	)	)	-RRB-
cord-263699-gosqpg3k	162	24	.	.	.
cord-263699-gosqpg3k	163	1	Finally	finally	RB
cord-263699-gosqpg3k	163	2	,	,	,
cord-263699-gosqpg3k	163	3	the	the	DT
cord-263699-gosqpg3k	163	4	newly	newly	RB
cord-263699-gosqpg3k	163	5	EV	ev	NN
cord-263699-gosqpg3k	163	6	procapsids	procapsid	NNS
cord-263699-gosqpg3k	163	7	are	be	VBP
cord-263699-gosqpg3k	163	8	secreted	secrete	VBN
cord-263699-gosqpg3k	163	9	into	into	IN
cord-263699-gosqpg3k	163	10	the	the	DT
cord-263699-gosqpg3k	163	11	extracellular	extracellular	JJ
cord-263699-gosqpg3k	163	12	medium	medium	NN
cord-263699-gosqpg3k	163	13	through	through	IN
cord-263699-gosqpg3k	163	14	a	a	DT
cord-263699-gosqpg3k	163	15	process	process	NN
cord-263699-gosqpg3k	163	16	in	in	IN
cord-263699-gosqpg3k	163	17	which	which	WDT
cord-263699-gosqpg3k	163	18	VP0	VP0	NNP
cord-263699-gosqpg3k	163	19	is	be	VBZ
cord-263699-gosqpg3k	163	20	cleaved	cleave	VBN
cord-263699-gosqpg3k	163	21	into	into	IN
cord-263699-gosqpg3k	163	22	VP2	VP2	NNP
cord-263699-gosqpg3k	163	23	and	and	CC
cord-263699-gosqpg3k	163	24	VP4	VP4	NNP
cord-263699-gosqpg3k	163	25	,	,	,
cord-263699-gosqpg3k	163	26	to	to	TO
cord-263699-gosqpg3k	163	27	form	form	VB
cord-263699-gosqpg3k	163	28	the	the	DT
cord-263699-gosqpg3k	163	29	mature	mature	JJ
cord-263699-gosqpg3k	163	30	,	,	,
cord-263699-gosqpg3k	163	31	infectious	infectious	JJ
cord-263699-gosqpg3k	163	32	virus	virus	NN
cord-263699-gosqpg3k	163	33	particles	particle	NNS
cord-263699-gosqpg3k	163	34	.	.	.
cord-263699-gosqpg3k	164	1	Although	although	IN
cord-263699-gosqpg3k	164	2	many	many	JJ
cord-263699-gosqpg3k	164	3	of	of	IN
cord-263699-gosqpg3k	164	4	the	the	DT
cord-263699-gosqpg3k	164	5	details	detail	NNS
cord-263699-gosqpg3k	164	6	of	of	IN
cord-263699-gosqpg3k	164	7	the	the	DT
cord-263699-gosqpg3k	164	8	EV	ev	NN
cord-263699-gosqpg3k	164	9	replication	replication	NN
cord-263699-gosqpg3k	164	10	cycle	cycle	NN
cord-263699-gosqpg3k	164	11	have	have	VBP
cord-263699-gosqpg3k	164	12	been	be	VBN
cord-263699-gosqpg3k	164	13	described	describe	VBN
cord-263699-gosqpg3k	164	14	,	,	,
cord-263699-gosqpg3k	164	15	the	the	DT
cord-263699-gosqpg3k	164	16	role	role	NN
cord-263699-gosqpg3k	164	17	of	of	IN
cord-263699-gosqpg3k	164	18	host	host	NN
cord-263699-gosqpg3k	164	19	factors	factor	NNS
cord-263699-gosqpg3k	164	20	in	in	IN
cord-263699-gosqpg3k	164	21	the	the	DT
cord-263699-gosqpg3k	164	22	replication	replication	NN
cord-263699-gosqpg3k	164	23	complexes	complex	NNS
cord-263699-gosqpg3k	164	24	of	of	IN
cord-263699-gosqpg3k	164	25	EV	EV	NNP
cord-263699-gosqpg3k	164	26	are	be	VBP
cord-263699-gosqpg3k	164	27	less	less	RBR
cord-263699-gosqpg3k	164	28	characterized	characterize	VBN
cord-263699-gosqpg3k	164	29	.	.	.
cord-263699-gosqpg3k	165	1	One	one	CD
cord-263699-gosqpg3k	165	2	of	of	IN
cord-263699-gosqpg3k	165	3	the	the	DT
cord-263699-gosqpg3k	165	4	most	most	RBS
cord-263699-gosqpg3k	165	5	intriguing	intriguing	JJ
cord-263699-gosqpg3k	165	6	features	feature	NNS
cord-263699-gosqpg3k	165	7	of	of	IN
cord-263699-gosqpg3k	165	8	EV	ev	NN
cord-263699-gosqpg3k	165	9	replication	replication	NN
cord-263699-gosqpg3k	165	10	is	be	VBZ
cord-263699-gosqpg3k	165	11	the	the	DT
cord-263699-gosqpg3k	165	12	participation	participation	NN
cord-263699-gosqpg3k	165	13	of	of	IN
cord-263699-gosqpg3k	165	14	the	the	DT
cord-263699-gosqpg3k	165	15	cellular	cellular	JJ
cord-263699-gosqpg3k	165	16	secretory	secretory	JJ
cord-263699-gosqpg3k	165	17	pathway	pathway	NN
cord-263699-gosqpg3k	165	18	in	in	IN
cord-263699-gosqpg3k	165	19	the	the	DT
cord-263699-gosqpg3k	165	20	infectious	infectious	JJ
cord-263699-gosqpg3k	165	21	process	process	NN
cord-263699-gosqpg3k	165	22	.	.	.
cord-263699-gosqpg3k	166	1	The	the	DT
cord-263699-gosqpg3k	166	2	inhibition	inhibition	NN
cord-263699-gosqpg3k	166	3	of	of	IN
cord-263699-gosqpg3k	166	4	this	this	DT
cord-263699-gosqpg3k	166	5	pathway	pathway	NN
cord-263699-gosqpg3k	166	6	by	by	IN
cord-263699-gosqpg3k	166	7	BFA	BFA	NNP
cord-263699-gosqpg3k	166	8	and	and	CC
cord-263699-gosqpg3k	166	9	GCA	GCA	NNP
cord-263699-gosqpg3k	166	10	revealed	reveal	VBD
cord-263699-gosqpg3k	166	11	that	that	IN
cord-263699-gosqpg3k	166	12	the	the	DT
cord-263699-gosqpg3k	166	13	RNA	RNA	NNP
cord-263699-gosqpg3k	166	14	replication	replication	NN
cord-263699-gosqpg3k	166	15	of	of	IN
cord-263699-gosqpg3k	166	16	many	many	JJ
cord-263699-gosqpg3k	166	17	members	member	NNS
cord-263699-gosqpg3k	166	18	of	of	IN
cord-263699-gosqpg3k	166	19	EV	ev	NN
cord-263699-gosqpg3k	166	20	genus	genus	NN
cord-263699-gosqpg3k	166	21	,	,	,
cord-263699-gosqpg3k	166	22	such	such	JJ
cord-263699-gosqpg3k	166	23	as	as	IN
cord-263699-gosqpg3k	166	24	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	166	25	,	,	,
cord-263699-gosqpg3k	166	26	CVB3	CVB3	NNPS
cord-263699-gosqpg3k	166	27	,	,	,
cord-263699-gosqpg3k	166	28	coxsackievirus	coxsackievirus	NNP
cord-263699-gosqpg3k	166	29	B4	B4	NNP
cord-263699-gosqpg3k	166	30	(	(	-LRB-
cord-263699-gosqpg3k	166	31	CVB4	CVB4	NNP
cord-263699-gosqpg3k	166	32	,	,	,
cord-263699-gosqpg3k	166	33	member	member	NN
cord-263699-gosqpg3k	166	34	of	of	IN
cord-263699-gosqpg3k	166	35	EV	EV	NNP
cord-263699-gosqpg3k	166	36	-	-	HYPH
cord-263699-gosqpg3k	166	37	B	b	NN
cord-263699-gosqpg3k	166	38	group	group	NN
cord-263699-gosqpg3k	166	39	)	)	-RRB-
cord-263699-gosqpg3k	166	40	,	,	,
cord-263699-gosqpg3k	166	41	coxsackievirus	coxsackievirus	NNP
cord-263699-gosqpg3k	166	42	A21	A21	NNP
cord-263699-gosqpg3k	166	43	(	(	-LRB-
cord-263699-gosqpg3k	166	44	CVA21	CVA21	NNP
cord-263699-gosqpg3k	166	45	,	,	,
cord-263699-gosqpg3k	166	46	member	member	NN
cord-263699-gosqpg3k	166	47	of	of	IN
cord-263699-gosqpg3k	166	48	EV	EV	NNP
cord-263699-gosqpg3k	166	49	-	-	HYPH
cord-263699-gosqpg3k	166	50	C	C	NNP
cord-263699-gosqpg3k	166	51	group	group	NN
cord-263699-gosqpg3k	166	52	)	)	-RRB-
cord-263699-gosqpg3k	166	53	,	,	,
cord-263699-gosqpg3k	166	54	enterovirus	enterovirus	NN
cord-263699-gosqpg3k	166	55	71	71	CD
cord-263699-gosqpg3k	167	1	(	(	-LRB-
cord-263699-gosqpg3k	167	2	EV71	EV71	NNP
cord-263699-gosqpg3k	167	3	,	,	,
cord-263699-gosqpg3k	167	4	member	member	NN
cord-263699-gosqpg3k	167	5	of	of	IN
cord-263699-gosqpg3k	167	6	EV	EV	NNP
cord-263699-gosqpg3k	167	7	-	-	HYPH
cord-263699-gosqpg3k	167	8	A	A	NNP
cord-263699-gosqpg3k	167	9	group	group	NN
cord-263699-gosqpg3k	167	10	)	)	-RRB-
cord-263699-gosqpg3k	167	11	,	,	,
cord-263699-gosqpg3k	167	12	echovirus	echovirus	NNP
cord-263699-gosqpg3k	167	13	11	11	CD
cord-263699-gosqpg3k	167	14	(	(	-LRB-
cord-263699-gosqpg3k	167	15	E11	E11	NNP
cord-263699-gosqpg3k	167	16	,	,	,
cord-263699-gosqpg3k	167	17	member	member	NN
cord-263699-gosqpg3k	167	18	of	of	IN
cord-263699-gosqpg3k	167	19	EV	EV	NNP
cord-263699-gosqpg3k	167	20	-	-	HYPH
cord-263699-gosqpg3k	167	21	B	b	NN
cord-263699-gosqpg3k	167	22	group	group	NN
cord-263699-gosqpg3k	167	23	)	)	-RRB-
cord-263699-gosqpg3k	167	24	,	,	,
cord-263699-gosqpg3k	167	25	and	and	CC
cord-263699-gosqpg3k	167	26	bovine	bovine	JJ
cord-263699-gosqpg3k	167	27	enterovirus	enterovirus	NN
cord-263699-gosqpg3k	167	28	type	type	NN
cord-263699-gosqpg3k	167	29	2	2	CD
cord-263699-gosqpg3k	168	1	(	(	-LRB-
cord-263699-gosqpg3k	168	2	BEV2	BEV2	NNP
cord-263699-gosqpg3k	168	3	,	,	,
cord-263699-gosqpg3k	168	4	member	member	NN
cord-263699-gosqpg3k	168	5	of	of	IN
cord-263699-gosqpg3k	168	6	EV	EV	NNP
cord-263699-gosqpg3k	168	7	-	-	HYPH
cord-263699-gosqpg3k	168	8	F	F	NNP
cord-263699-gosqpg3k	168	9	group	group	NN
cord-263699-gosqpg3k	168	10	)	)	-RRB-
cord-263699-gosqpg3k	168	11	are	be	VBP
cord-263699-gosqpg3k	168	12	sensitive	sensitive	JJ
cord-263699-gosqpg3k	168	13	to	to	IN
cord-263699-gosqpg3k	168	14	these	these	DT
cord-263699-gosqpg3k	168	15	drugs	drug	NNS
cord-263699-gosqpg3k	168	16	[	[	-LRB-
cord-263699-gosqpg3k	168	17	51	51	CD
cord-263699-gosqpg3k	168	18	,	,	,
cord-263699-gosqpg3k	168	19	60	60	CD
cord-263699-gosqpg3k	168	20	,	,	,
cord-263699-gosqpg3k	168	21	61	61	CD
cord-263699-gosqpg3k	168	22	,	,	,
cord-263699-gosqpg3k	168	23	64	64	CD
cord-263699-gosqpg3k	168	24	,	,	,
cord-263699-gosqpg3k	168	25	[	[	-LRB-
cord-263699-gosqpg3k	168	26	99	99	CD
cord-263699-gosqpg3k	168	27	]	]	-RRB-
cord-263699-gosqpg3k	168	28	[	[	-LRB-
cord-263699-gosqpg3k	168	29	100	100	CD
cord-263699-gosqpg3k	168	30	]	]	-RRB-
cord-263699-gosqpg3k	168	31	[	[	-LRB-
cord-263699-gosqpg3k	168	32	101	101	CD
cord-263699-gosqpg3k	168	33	]	]	-RRB-
cord-263699-gosqpg3k	168	34	[	[	-LRB-
cord-263699-gosqpg3k	168	35	102	102	CD
cord-263699-gosqpg3k	168	36	]	]	-RRB-
cord-263699-gosqpg3k	168	37	[	[	-LRB-
cord-263699-gosqpg3k	168	38	103	103	CD
cord-263699-gosqpg3k	168	39	]	]	-RRB-
cord-263699-gosqpg3k	168	40	.	.	.
cord-263699-gosqpg3k	169	1	Furthermore	furthermore	RB
cord-263699-gosqpg3k	169	2	,	,	,
cord-263699-gosqpg3k	169	3	the	the	DT
cord-263699-gosqpg3k	169	4	replication	replication	NN
cord-263699-gosqpg3k	169	5	of	of	IN
cord-263699-gosqpg3k	169	6	human	human	JJ
cord-263699-gosqpg3k	169	7	rhinovirus	rhinovirus	NN
cord-263699-gosqpg3k	169	8	2	2	CD
cord-263699-gosqpg3k	169	9	(	(	-LRB-
cord-263699-gosqpg3k	169	10	HRV2	HRV2	NNP
cord-263699-gosqpg3k	169	11	,	,	,
cord-263699-gosqpg3k	169	12	member	member	NN
cord-263699-gosqpg3k	169	13	of	of	IN
cord-263699-gosqpg3k	169	14	RV	RV	NNP
cord-263699-gosqpg3k	169	15	-	-	:
cord-263699-gosqpg3k	169	16	A	a	DT
cord-263699-gosqpg3k	169	17	group	group	NN
cord-263699-gosqpg3k	169	18	)	)	-RRB-
cord-263699-gosqpg3k	169	19	as	as	RB
cord-263699-gosqpg3k	169	20	well	well	RB
cord-263699-gosqpg3k	169	21	as	as	IN
cord-263699-gosqpg3k	169	22	human	human	JJ
cord-263699-gosqpg3k	169	23	rhinovirus	rhinovirus	NN
cord-263699-gosqpg3k	169	24	14	14	CD
cord-263699-gosqpg3k	169	25	(	(	-LRB-
cord-263699-gosqpg3k	169	26	HRV14	hrv14	NN
cord-263699-gosqpg3k	169	27	,	,	,
cord-263699-gosqpg3k	169	28	member	member	NN
cord-263699-gosqpg3k	169	29	of	of	IN
cord-263699-gosqpg3k	169	30	RV	RV	NNP
cord-263699-gosqpg3k	169	31	-	-	HYPH
cord-263699-gosqpg3k	169	32	B	b	NN
cord-263699-gosqpg3k	169	33	group	group	NN
cord-263699-gosqpg3k	169	34	)	)	-RRB-
cord-263699-gosqpg3k	169	35	was	be	VBD
cord-263699-gosqpg3k	169	36	also	also	RB
cord-263699-gosqpg3k	169	37	inhibited	inhibit	VBN
cord-263699-gosqpg3k	169	38	by	by	IN
cord-263699-gosqpg3k	169	39	BFA	BFA	NNP
cord-263699-gosqpg3k	169	40	and	and	CC
cord-263699-gosqpg3k	169	41	GCA	GCA	NNP
cord-263699-gosqpg3k	169	42	[	[	-LRB-
cord-263699-gosqpg3k	169	43	65	65	CD
cord-263699-gosqpg3k	169	44	]	]	-RRB-
cord-263699-gosqpg3k	169	45	.	.	.
cord-263699-gosqpg3k	170	1	The	the	DT
cord-263699-gosqpg3k	170	2	reason	reason	NN
cord-263699-gosqpg3k	170	3	for	for	IN
cord-263699-gosqpg3k	170	4	this	this	DT
cord-263699-gosqpg3k	170	5	blockage	blockage	NN
cord-263699-gosqpg3k	170	6	is	be	VBZ
cord-263699-gosqpg3k	170	7	unknown	unknown	JJ
cord-263699-gosqpg3k	170	8	,	,	,
cord-263699-gosqpg3k	170	9	although	although	IN
cord-263699-gosqpg3k	170	10	it	-PRON-	PRP
cord-263699-gosqpg3k	170	11	has	have	VBZ
cord-263699-gosqpg3k	170	12	been	be	VBN
cord-263699-gosqpg3k	170	13	reported	report	VBN
cord-263699-gosqpg3k	170	14	that	that	IN
cord-263699-gosqpg3k	170	15	these	these	DT
cord-263699-gosqpg3k	170	16	inhibitors	inhibitor	NNS
cord-263699-gosqpg3k	170	17	do	do	VBP
cord-263699-gosqpg3k	170	18	not	not	RB
cord-263699-gosqpg3k	170	19	alter	alter	VB
cord-263699-gosqpg3k	170	20	the	the	DT
cord-263699-gosqpg3k	170	21	formation	formation	NN
cord-263699-gosqpg3k	170	22	of	of	IN
cord-263699-gosqpg3k	170	23	the	the	DT
cord-263699-gosqpg3k	170	24	replication	replication	NN
cord-263699-gosqpg3k	170	25	complexes	complex	NNS
cord-263699-gosqpg3k	170	26	of	of	IN
cord-263699-gosqpg3k	170	27	EV	EV	NNP
cord-263699-gosqpg3k	170	28	,	,	,
cord-263699-gosqpg3k	170	29	but	but	CC
cord-263699-gosqpg3k	170	30	rather	rather	RB
cord-263699-gosqpg3k	170	31	inhibit	inhibit	VB
cord-263699-gosqpg3k	170	32	the	the	DT
cord-263699-gosqpg3k	170	33	proper	proper	JJ
cord-263699-gosqpg3k	170	34	functioning	functioning	NN
cord-263699-gosqpg3k	170	35	of	of	IN
cord-263699-gosqpg3k	170	36	these	these	DT
cord-263699-gosqpg3k	170	37	viral	viral	JJ
cord-263699-gosqpg3k	170	38	organelles	organelle	NNS
cord-263699-gosqpg3k	170	39	,	,	,
cord-263699-gosqpg3k	170	40	which	which	WDT
cord-263699-gosqpg3k	170	41	are	be	VBP
cord-263699-gosqpg3k	170	42	unable	unable	JJ
cord-263699-gosqpg3k	170	43	to	to	TO
cord-263699-gosqpg3k	170	44	support	support	VB
cord-263699-gosqpg3k	170	45	the	the	DT
cord-263699-gosqpg3k	170	46	viral	viral	JJ
cord-263699-gosqpg3k	170	47	RNA	RNA	NNP
cord-263699-gosqpg3k	170	48	synthesis	synthesis	NN
cord-263699-gosqpg3k	170	49	[	[	-LRB-
cord-263699-gosqpg3k	170	50	58	58	CD
cord-263699-gosqpg3k	170	51	]	]	-RRB-
cord-263699-gosqpg3k	170	52	.	.	.
cord-263699-gosqpg3k	171	1	Also	also	RB
cord-263699-gosqpg3k	171	2	,	,	,
cord-263699-gosqpg3k	171	3	it	-PRON-	PRP
cord-263699-gosqpg3k	171	4	has	have	VBZ
cord-263699-gosqpg3k	171	5	been	be	VBN
cord-263699-gosqpg3k	171	6	shown	show	VBN
cord-263699-gosqpg3k	171	7	that	that	IN
cord-263699-gosqpg3k	171	8	the	the	DT
cord-263699-gosqpg3k	171	9	blockage	blockage	NN
cord-263699-gosqpg3k	171	10	of	of	IN
cord-263699-gosqpg3k	171	11	RNA	RNA	NNP
cord-263699-gosqpg3k	171	12	replication	replication	NN
cord-263699-gosqpg3k	171	13	produced	produce	VBN
cord-263699-gosqpg3k	171	14	by	by	IN
cord-263699-gosqpg3k	171	15	BFA	BFA	NNP
cord-263699-gosqpg3k	171	16	and	and	CC
cord-263699-gosqpg3k	171	17	GCA	GCA	NNP
cord-263699-gosqpg3k	171	18	is	be	VBZ
cord-263699-gosqpg3k	171	19	related	relate	VBN
cord-263699-gosqpg3k	171	20	to	to	IN
cord-263699-gosqpg3k	171	21	the	the	DT
cord-263699-gosqpg3k	171	22	activity	activity	NN
cord-263699-gosqpg3k	171	23	of	of	IN
cord-263699-gosqpg3k	171	24	GBF1	GBF1	NNP
cord-263699-gosqpg3k	171	25	since	since	IN
cord-263699-gosqpg3k	171	26	the	the	DT
cord-263699-gosqpg3k	171	27	overexpression	overexpression	NN
cord-263699-gosqpg3k	171	28	of	of	IN
cord-263699-gosqpg3k	171	29	GBF1	GBF1	NNP
cord-263699-gosqpg3k	171	30	prevents	prevent	VBZ
cord-263699-gosqpg3k	171	31	the	the	DT
cord-263699-gosqpg3k	171	32	effects	effect	NNS
cord-263699-gosqpg3k	171	33	of	of	IN
cord-263699-gosqpg3k	171	34	these	these	DT
cord-263699-gosqpg3k	171	35	drugs	drug	NNS
cord-263699-gosqpg3k	171	36	on	on	IN
cord-263699-gosqpg3k	171	37	EV	ev	NN
cord-263699-gosqpg3k	171	38	replication	replication	NN
cord-263699-gosqpg3k	171	39	[	[	-LRB-
cord-263699-gosqpg3k	171	40	58	58	CD
cord-263699-gosqpg3k	171	41	,	,	,
cord-263699-gosqpg3k	171	42	61	61	CD
cord-263699-gosqpg3k	171	43	,	,	,
cord-263699-gosqpg3k	171	44	64	64	CD
cord-263699-gosqpg3k	171	45	,	,	,
cord-263699-gosqpg3k	171	46	65	65	CD
cord-263699-gosqpg3k	171	47	]	]	-RRB-
cord-263699-gosqpg3k	171	48	.	.	.
cord-263699-gosqpg3k	172	1	Moreover	moreover	RB
cord-263699-gosqpg3k	172	2	,	,	,
cord-263699-gosqpg3k	172	3	GBF1	GBF1	NNP
cord-263699-gosqpg3k	172	4	knockdown	knockdown	NN
cord-263699-gosqpg3k	172	5	confirms	confirm	VBZ
cord-263699-gosqpg3k	172	6	that	that	IN
cord-263699-gosqpg3k	172	7	the	the	DT
cord-263699-gosqpg3k	172	8	reduction	reduction	NN
cord-263699-gosqpg3k	172	9	of	of	IN
cord-263699-gosqpg3k	172	10	this	this	DT
cord-263699-gosqpg3k	172	11	factor	factor	NN
cord-263699-gosqpg3k	172	12	reduces	reduce	VBZ
cord-263699-gosqpg3k	172	13	the	the	DT
cord-263699-gosqpg3k	172	14	EV	EV	NNP
cord-263699-gosqpg3k	172	15	RNA	RNA	NNP
cord-263699-gosqpg3k	172	16	replication	replication	NN
cord-263699-gosqpg3k	172	17	[	[	-LRB-
cord-263699-gosqpg3k	172	18	58	58	CD
cord-263699-gosqpg3k	172	19	,	,	,
cord-263699-gosqpg3k	172	20	[	[	-LRB-
cord-263699-gosqpg3k	172	21	61	61	CD
cord-263699-gosqpg3k	172	22	]	]	-RRB-
cord-263699-gosqpg3k	172	23	[	[	-LRB-
cord-263699-gosqpg3k	172	24	62	62	CD
cord-263699-gosqpg3k	172	25	]	]	-RRB-
cord-263699-gosqpg3k	172	26	[	[	-LRB-
cord-263699-gosqpg3k	172	27	63	63	CD
cord-263699-gosqpg3k	172	28	]	]	-RRB-
cord-263699-gosqpg3k	172	29	[	[	-LRB-
cord-263699-gosqpg3k	172	30	64	64	CD
cord-263699-gosqpg3k	172	31	]	]	-RRB-
cord-263699-gosqpg3k	172	32	104	104	CD
cord-263699-gosqpg3k	172	33	]	]	-RRB-
cord-263699-gosqpg3k	172	34	.	.	.
cord-263699-gosqpg3k	173	1	Although	although	IN
cord-263699-gosqpg3k	173	2	the	the	DT
cord-263699-gosqpg3k	173	3	precise	precise	JJ
cord-263699-gosqpg3k	173	4	role	role	NN
cord-263699-gosqpg3k	173	5	of	of	IN
cord-263699-gosqpg3k	173	6	GBF1	GBF1	NNP
cord-263699-gosqpg3k	173	7	in	in	IN
cord-263699-gosqpg3k	173	8	EV	ev	NN
cord-263699-gosqpg3k	173	9	replication	replication	NN
cord-263699-gosqpg3k	173	10	is	be	VBZ
cord-263699-gosqpg3k	173	11	unknown	unknown	JJ
cord-263699-gosqpg3k	173	12	,	,	,
cord-263699-gosqpg3k	173	13	further	further	JJ
cord-263699-gosqpg3k	173	14	analysis	analysis	NN
cord-263699-gosqpg3k	173	15	of	of	IN
cord-263699-gosqpg3k	173	16	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	173	17	,	,	,
cord-263699-gosqpg3k	173	18	CVB3	CVB3	NNPS
cord-263699-gosqpg3k	173	19	,	,	,
cord-263699-gosqpg3k	173	20	and	and	CC
cord-263699-gosqpg3k	173	21	EV71	EV71	NNP
cord-263699-gosqpg3k	173	22	infection	infection	NN
cord-263699-gosqpg3k	173	23	revealed	reveal	VBD
cord-263699-gosqpg3k	173	24	that	that	IN
cord-263699-gosqpg3k	173	25	the	the	DT
cord-263699-gosqpg3k	173	26	N	n	CD
cord-263699-gosqpg3k	173	27	-	-	HYPH
cord-263699-gosqpg3k	173	28	terminal	terminal	NN
cord-263699-gosqpg3k	173	29	region	region	NN
cord-263699-gosqpg3k	173	30	of	of	IN
cord-263699-gosqpg3k	173	31	GBF1	GBF1	NNP
cord-263699-gosqpg3k	173	32	interacts	interact	VBZ
cord-263699-gosqpg3k	173	33	with	with	IN
cord-263699-gosqpg3k	173	34	the	the	DT
cord-263699-gosqpg3k	173	35	viral	viral	JJ
cord-263699-gosqpg3k	173	36	3A	3A	NNP
cord-263699-gosqpg3k	173	37	protein	protein	NN
cord-263699-gosqpg3k	173	38	;	;	:
cord-263699-gosqpg3k	173	39	this	this	DT
cord-263699-gosqpg3k	173	40	interaction	interaction	NN
cord-263699-gosqpg3k	173	41	,	,	,
cord-263699-gosqpg3k	173	42	in	in	IN
cord-263699-gosqpg3k	173	43	turn	turn	NN
cord-263699-gosqpg3k	173	44	,	,	,
cord-263699-gosqpg3k	173	45	stimulates	stimulate	VBZ
cord-263699-gosqpg3k	173	46	the	the	DT
cord-263699-gosqpg3k	173	47	association	association	NN
cord-263699-gosqpg3k	173	48	of	of	IN
cord-263699-gosqpg3k	173	49	GBF1	GBF1	NNP
cord-263699-gosqpg3k	173	50	with	with	IN
cord-263699-gosqpg3k	173	51	the	the	DT
cord-263699-gosqpg3k	173	52	membranes	membrane	NNS
cord-263699-gosqpg3k	173	53	where	where	WRB
cord-263699-gosqpg3k	173	54	the	the	DT
cord-263699-gosqpg3k	173	55	EV	EV	NNP
cord-263699-gosqpg3k	173	56	replication	replication	NN
cord-263699-gosqpg3k	173	57	complexes	complex	NNS
cord-263699-gosqpg3k	173	58	are	be	VBP
cord-263699-gosqpg3k	173	59	located	locate	VBN
cord-263699-gosqpg3k	173	60	[	[	-LRB-
cord-263699-gosqpg3k	173	61	58	58	CD
cord-263699-gosqpg3k	173	62	,	,	,
cord-263699-gosqpg3k	173	63	59	59	CD
cord-263699-gosqpg3k	173	64	,	,	,
cord-263699-gosqpg3k	173	65	64	64	CD
cord-263699-gosqpg3k	173	66	,	,	,
cord-263699-gosqpg3k	173	67	[	[	-LRB-
cord-263699-gosqpg3k	173	68	105	105	CD
cord-263699-gosqpg3k	173	69	]	]	-RRB-
cord-263699-gosqpg3k	173	70	[	[	-LRB-
cord-263699-gosqpg3k	173	71	106	106	CD
cord-263699-gosqpg3k	173	72	]	]	-RRB-
cord-263699-gosqpg3k	173	73	[	[	-LRB-
cord-263699-gosqpg3k	173	74	107	107	CD
cord-263699-gosqpg3k	173	75	]	]	-RRB-
cord-263699-gosqpg3k	173	76	[	[	-LRB-
cord-263699-gosqpg3k	173	77	108	108	CD
cord-263699-gosqpg3k	173	78	]	]	-RRB-
cord-263699-gosqpg3k	173	79	,	,	,
cord-263699-gosqpg3k	173	80	inducing	induce	VBG
cord-263699-gosqpg3k	173	81	ultimately	ultimately	RB
cord-263699-gosqpg3k	173	82	a	a	DT
cord-263699-gosqpg3k	173	83	steady	steady	JJ
cord-263699-gosqpg3k	173	84	increase	increase	NN
cord-263699-gosqpg3k	173	85	in	in	IN
cord-263699-gosqpg3k	173	86	the	the	DT
cord-263699-gosqpg3k	173	87	activation	activation	NN
cord-263699-gosqpg3k	173	88	of	of	IN
cord-263699-gosqpg3k	173	89	Arf1	Arf1	NNP
cord-263699-gosqpg3k	173	90	,	,	,
cord-263699-gosqpg3k	173	91	Arf3	Arf3	NNP
cord-263699-gosqpg3k	173	92	,	,	,
cord-263699-gosqpg3k	173	93	and	and	CC
cord-263699-gosqpg3k	173	94	Arf5	Arf5	NNP
cord-263699-gosqpg3k	173	95	[	[	-LRB-
cord-263699-gosqpg3k	173	96	64	64	CD
cord-263699-gosqpg3k	173	97	,	,	,
cord-263699-gosqpg3k	173	98	104	104	CD
cord-263699-gosqpg3k	173	99	,	,	,
cord-263699-gosqpg3k	173	100	109	109	CD
cord-263699-gosqpg3k	173	101	]	]	-RRB-
cord-263699-gosqpg3k	173	102	.	.	.
cord-263699-gosqpg3k	174	1	Although	although	IN
cord-263699-gosqpg3k	174	2	it	-PRON-	PRP
cord-263699-gosqpg3k	174	3	is	be	VBZ
cord-263699-gosqpg3k	174	4	generally	generally	RB
cord-263699-gosqpg3k	174	5	accepted	accept	VBN
cord-263699-gosqpg3k	174	6	that	that	IN
cord-263699-gosqpg3k	174	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	174	8	interacts	interact	VBZ
cord-263699-gosqpg3k	174	9	with	with	IN
cord-263699-gosqpg3k	174	10	the	the	DT
cord-263699-gosqpg3k	174	11	3A	3A	NNP
cord-263699-gosqpg3k	174	12	protein	protein	NNP
cord-263699-gosqpg3k	174	13	,	,	,
cord-263699-gosqpg3k	174	14	the	the	DT
cord-263699-gosqpg3k	174	15	importance	importance	NN
cord-263699-gosqpg3k	174	16	of	of	IN
cord-263699-gosqpg3k	174	17	this	this	DT
cord-263699-gosqpg3k	174	18	interaction	interaction	NN
cord-263699-gosqpg3k	174	19	for	for	IN
cord-263699-gosqpg3k	174	20	the	the	DT
cord-263699-gosqpg3k	174	21	replication	replication	NN
cord-263699-gosqpg3k	174	22	of	of	IN
cord-263699-gosqpg3k	174	23	the	the	DT
cord-263699-gosqpg3k	174	24	EV	EV	NNP
cord-263699-gosqpg3k	174	25	RNA	RNA	NNP
cord-263699-gosqpg3k	174	26	remains	remain	VBZ
cord-263699-gosqpg3k	174	27	to	to	TO
cord-263699-gosqpg3k	174	28	be	be	VB
cord-263699-gosqpg3k	174	29	elucidated	elucidate	VBN
cord-263699-gosqpg3k	174	30	.	.	.
cord-263699-gosqpg3k	175	1	The	the	DT
cord-263699-gosqpg3k	175	2	use	use	NN
cord-263699-gosqpg3k	175	3	of	of	IN
cord-263699-gosqpg3k	175	4	different	different	JJ
cord-263699-gosqpg3k	175	5	GBF1	GBF1	NNP
cord-263699-gosqpg3k	175	6	mutants	mutant	NNS
cord-263699-gosqpg3k	175	7	revealed	reveal	VBD
cord-263699-gosqpg3k	175	8	that	that	IN
cord-263699-gosqpg3k	175	9	mutations	mutation	NNS
cord-263699-gosqpg3k	175	10	in	in	IN
cord-263699-gosqpg3k	175	11	this	this	DT
cord-263699-gosqpg3k	175	12	protein	protein	NN
cord-263699-gosqpg3k	175	13	that	that	WDT
cord-263699-gosqpg3k	175	14	abolish	abolish	VBP
cord-263699-gosqpg3k	175	15	the	the	DT
cord-263699-gosqpg3k	175	16	interaction	interaction	NN
cord-263699-gosqpg3k	175	17	with	with	IN
cord-263699-gosqpg3k	175	18	3A	3A	NNP
cord-263699-gosqpg3k	175	19	reduce	reduce	VB
cord-263699-gosqpg3k	175	20	the	the	DT
cord-263699-gosqpg3k	175	21	ability	ability	NN
cord-263699-gosqpg3k	175	22	of	of	IN
cord-263699-gosqpg3k	175	23	this	this	DT
cord-263699-gosqpg3k	175	24	cellular	cellular	JJ
cord-263699-gosqpg3k	175	25	factor	factor	NN
cord-263699-gosqpg3k	175	26	to	to	TO
cord-263699-gosqpg3k	175	27	support	support	VB
cord-263699-gosqpg3k	175	28	EV	EV	NNP
cord-263699-gosqpg3k	175	29	RNA	RNA	NNP
cord-263699-gosqpg3k	175	30	replication	replication	NN
cord-263699-gosqpg3k	175	31	[	[	-LRB-
cord-263699-gosqpg3k	175	32	58	58	CD
cord-263699-gosqpg3k	175	33	,	,	,
cord-263699-gosqpg3k	175	34	59	59	CD
cord-263699-gosqpg3k	175	35	]	]	-RRB-
cord-263699-gosqpg3k	175	36	.	.	.
cord-263699-gosqpg3k	176	1	However	however	RB
cord-263699-gosqpg3k	176	2	,	,	,
cord-263699-gosqpg3k	176	3	it	-PRON-	PRP
cord-263699-gosqpg3k	176	4	has	have	VBZ
cord-263699-gosqpg3k	176	5	also	also	RB
cord-263699-gosqpg3k	176	6	been	be	VBN
cord-263699-gosqpg3k	176	7	found	find	VBN
cord-263699-gosqpg3k	176	8	that	that	IN
cord-263699-gosqpg3k	176	9	an	an	DT
cord-263699-gosqpg3k	176	10	EV	EV	NNP
cord-263699-gosqpg3k	176	11	mutant	mutant	JJ
cord-263699-gosqpg3k	176	12	strain	strain	NN
cord-263699-gosqpg3k	176	13	with	with	IN
cord-263699-gosqpg3k	176	14	a	a	DT
cord-263699-gosqpg3k	176	15	3A	3a	NN
cord-263699-gosqpg3k	176	16	protein	protein	NN
cord-263699-gosqpg3k	176	17	incapable	incapable	JJ
cord-263699-gosqpg3k	176	18	of	of	IN
cord-263699-gosqpg3k	176	19	interacting	interact	VBG
cord-263699-gosqpg3k	176	20	with	with	IN
cord-263699-gosqpg3k	176	21	GBF1	GBF1	NNP
cord-263699-gosqpg3k	176	22	replicates	replicate	VBZ
cord-263699-gosqpg3k	176	23	to	to	IN
cord-263699-gosqpg3k	176	24	a	a	DT
cord-263699-gosqpg3k	176	25	similar	similar	JJ
cord-263699-gosqpg3k	176	26	extent	extent	NN
cord-263699-gosqpg3k	176	27	as	as	IN
cord-263699-gosqpg3k	176	28	the	the	DT
cord-263699-gosqpg3k	176	29	wild	wild	JJ
cord-263699-gosqpg3k	176	30	type	type	NN
cord-263699-gosqpg3k	176	31	virus	virus	NN
cord-263699-gosqpg3k	176	32	does	do	VBZ
cord-263699-gosqpg3k	176	33	[	[	-LRB-
cord-263699-gosqpg3k	176	34	58	58	CD
cord-263699-gosqpg3k	176	35	,	,	,
cord-263699-gosqpg3k	176	36	105	105	CD
cord-263699-gosqpg3k	176	37	,	,	,
cord-263699-gosqpg3k	176	38	108	108	CD
cord-263699-gosqpg3k	176	39	]	]	-RRB-
cord-263699-gosqpg3k	176	40	,	,	,
cord-263699-gosqpg3k	176	41	suggesting	suggest	VBG
cord-263699-gosqpg3k	176	42	that	that	IN
cord-263699-gosqpg3k	176	43	the	the	DT
cord-263699-gosqpg3k	176	44	interaction	interaction	NN
cord-263699-gosqpg3k	176	45	GBF1	GBF1	NNP
cord-263699-gosqpg3k	176	46	-	-	HYPH
cord-263699-gosqpg3k	176	47	3A	3A	NNP
cord-263699-gosqpg3k	176	48	is	be	VBZ
cord-263699-gosqpg3k	176	49	dispensable	dispensable	JJ
cord-263699-gosqpg3k	176	50	for	for	IN
cord-263699-gosqpg3k	176	51	the	the	DT
cord-263699-gosqpg3k	176	52	EV	ev	NN
cord-263699-gosqpg3k	176	53	replication	replication	NN
cord-263699-gosqpg3k	176	54	.	.	.
cord-263699-gosqpg3k	177	1	In	in	IN
cord-263699-gosqpg3k	177	2	this	this	DT
cord-263699-gosqpg3k	177	3	regard	regard	NN
cord-263699-gosqpg3k	177	4	,	,	,
cord-263699-gosqpg3k	177	5	it	-PRON-	PRP
cord-263699-gosqpg3k	177	6	has	have	VBZ
cord-263699-gosqpg3k	177	7	also	also	RB
cord-263699-gosqpg3k	177	8	been	be	VBN
cord-263699-gosqpg3k	177	9	found	find	VBN
cord-263699-gosqpg3k	177	10	that	that	IN
cord-263699-gosqpg3k	177	11	even	even	RB
cord-263699-gosqpg3k	177	12	though	though	IN
cord-263699-gosqpg3k	177	13	GBF1	GBF1	NNP
cord-263699-gosqpg3k	177	14	can	can	MD
cord-263699-gosqpg3k	177	15	be	be	VB
cord-263699-gosqpg3k	177	16	recruited	recruit	VBN
cord-263699-gosqpg3k	177	17	to	to	IN
cord-263699-gosqpg3k	177	18	the	the	DT
cord-263699-gosqpg3k	177	19	replication	replication	NN
cord-263699-gosqpg3k	177	20	complexes	complex	NNS
cord-263699-gosqpg3k	177	21	formed	form	VBN
cord-263699-gosqpg3k	177	22	by	by	IN
cord-263699-gosqpg3k	177	23	HRV2	HRV2	NNP
cord-263699-gosqpg3k	177	24	and	and	CC
cord-263699-gosqpg3k	177	25	HRV14	HRV14	NNP
cord-263699-gosqpg3k	177	26	,	,	,
cord-263699-gosqpg3k	177	27	the	the	DT
cord-263699-gosqpg3k	177	28	3A	3A	NNP
cord-263699-gosqpg3k	177	29	protein	protein	NN
cord-263699-gosqpg3k	177	30	of	of	IN
cord-263699-gosqpg3k	177	31	HRV14	HRV14	NNP
cord-263699-gosqpg3k	177	32	only	only	RB
cord-263699-gosqpg3k	177	33	shows	show	VBZ
cord-263699-gosqpg3k	177	34	a	a	DT
cord-263699-gosqpg3k	177	35	slight	slight	JJ
cord-263699-gosqpg3k	177	36	interaction	interaction	NN
cord-263699-gosqpg3k	177	37	with	with	IN
cord-263699-gosqpg3k	177	38	GBF1	GBF1	NNP
cord-263699-gosqpg3k	177	39	,	,	,
cord-263699-gosqpg3k	177	40	whereas	whereas	IN
cord-263699-gosqpg3k	177	41	the	the	DT
cord-263699-gosqpg3k	177	42	3A	3A	NNP
cord-263699-gosqpg3k	177	43	protein	protein	NN
cord-263699-gosqpg3k	177	44	of	of	IN
cord-263699-gosqpg3k	177	45	HRV2	HRV2	NNP
cord-263699-gosqpg3k	177	46	did	do	VBD
cord-263699-gosqpg3k	177	47	not	not	RB
cord-263699-gosqpg3k	177	48	interact	interact	VB
cord-263699-gosqpg3k	177	49	at	at	RB
cord-263699-gosqpg3k	177	50	all	all	RB
cord-263699-gosqpg3k	177	51	[	[	-LRB-
cord-263699-gosqpg3k	177	52	65	65	CD
cord-263699-gosqpg3k	177	53	,	,	,
cord-263699-gosqpg3k	177	54	107	107	CD
cord-263699-gosqpg3k	177	55	]	]	-RRB-
cord-263699-gosqpg3k	177	56	,	,	,
cord-263699-gosqpg3k	177	57	indicating	indicate	VBG
cord-263699-gosqpg3k	177	58	that	that	IN
cord-263699-gosqpg3k	177	59	the	the	DT
cord-263699-gosqpg3k	177	60	recruitment	recruitment	NN
cord-263699-gosqpg3k	177	61	of	of	IN
cord-263699-gosqpg3k	177	62	GBF1	GBF1	NNP
cord-263699-gosqpg3k	177	63	to	to	IN
cord-263699-gosqpg3k	177	64	the	the	DT
cord-263699-gosqpg3k	177	65	replication	replication	NN
cord-263699-gosqpg3k	177	66	complexes	complex	NNS
cord-263699-gosqpg3k	177	67	of	of	IN
cord-263699-gosqpg3k	177	68	EV	EV	NNP
cord-263699-gosqpg3k	177	69	is	be	VBZ
cord-263699-gosqpg3k	177	70	not	not	RB
cord-263699-gosqpg3k	177	71	dependent	dependent	JJ
cord-263699-gosqpg3k	177	72	on	on	IN
cord-263699-gosqpg3k	177	73	its	-PRON-	PRP$
cord-263699-gosqpg3k	177	74	interaction	interaction	NN
cord-263699-gosqpg3k	177	75	with	with	IN
cord-263699-gosqpg3k	177	76	3A.	3a.	CD
cord-263699-gosqpg3k	177	77	Reconciling	reconcile	VBG
cord-263699-gosqpg3k	177	78	these	these	DT
cord-263699-gosqpg3k	177	79	findings	finding	NNS
cord-263699-gosqpg3k	177	80	is	be	VBZ
cord-263699-gosqpg3k	177	81	complicated	complicate	VBN
cord-263699-gosqpg3k	177	82	;	;	:
cord-263699-gosqpg3k	177	83	however	however	RB
cord-263699-gosqpg3k	177	84	,	,	,
cord-263699-gosqpg3k	177	85	it	-PRON-	PRP
cord-263699-gosqpg3k	177	86	is	be	VBZ
cord-263699-gosqpg3k	177	87	possible	possible	JJ
cord-263699-gosqpg3k	177	88	that	that	IN
cord-263699-gosqpg3k	177	89	mutations	mutation	NNS
cord-263699-gosqpg3k	177	90	in	in	IN
cord-263699-gosqpg3k	177	91	GBF1	GBF1	NNP
cord-263699-gosqpg3k	177	92	that	that	WDT
cord-263699-gosqpg3k	177	93	alter	alter	VB
cord-263699-gosqpg3k	177	94	its	-PRON-	PRP$
cord-263699-gosqpg3k	177	95	interaction	interaction	NN
cord-263699-gosqpg3k	177	96	with	with	IN
cord-263699-gosqpg3k	177	97	3A	3A	NNP
cord-263699-gosqpg3k	177	98	might	may	MD
cord-263699-gosqpg3k	177	99	also	also	RB
cord-263699-gosqpg3k	177	100	abolish	abolish	VB
cord-263699-gosqpg3k	177	101	the	the	DT
cord-263699-gosqpg3k	177	102	ability	ability	NN
cord-263699-gosqpg3k	177	103	of	of	IN
cord-263699-gosqpg3k	177	104	GBF1	GBF1	NNP
cord-263699-gosqpg3k	177	105	to	to	TO
cord-263699-gosqpg3k	177	106	interact	interact	VB
cord-263699-gosqpg3k	177	107	with	with	IN
cord-263699-gosqpg3k	177	108	other	other	JJ
cord-263699-gosqpg3k	177	109	cellular	cellular	JJ
cord-263699-gosqpg3k	177	110	factors	factor	NNS
cord-263699-gosqpg3k	177	111	needed	need	VBN
cord-263699-gosqpg3k	177	112	for	for	IN
cord-263699-gosqpg3k	177	113	the	the	DT
cord-263699-gosqpg3k	177	114	proper	proper	JJ
cord-263699-gosqpg3k	177	115	function	function	NN
cord-263699-gosqpg3k	177	116	of	of	IN
cord-263699-gosqpg3k	177	117	this	this	DT
cord-263699-gosqpg3k	177	118	GEF	GEF	NNP
cord-263699-gosqpg3k	177	119	in	in	IN
cord-263699-gosqpg3k	177	120	the	the	DT
cord-263699-gosqpg3k	177	121	RNA	RNA	NNP
cord-263699-gosqpg3k	177	122	replication	replication	NN
cord-263699-gosqpg3k	177	123	of	of	IN
cord-263699-gosqpg3k	177	124	EV	EV	NNP
cord-263699-gosqpg3k	177	125	,	,	,
cord-263699-gosqpg3k	177	126	an	an	DT
cord-263699-gosqpg3k	177	127	effect	effect	NN
cord-263699-gosqpg3k	177	128	that	that	WDT
cord-263699-gosqpg3k	177	129	is	be	VBZ
cord-263699-gosqpg3k	177	130	not	not	RB
cord-263699-gosqpg3k	177	131	observed	observe	VBN
cord-263699-gosqpg3k	177	132	when	when	WRB
cord-263699-gosqpg3k	177	133	the	the	DT
cord-263699-gosqpg3k	177	134	3A	3A	NNP
cord-263699-gosqpg3k	177	135	protein	protein	NNP
cord-263699-gosqpg3k	177	136	is	be	VBZ
cord-263699-gosqpg3k	177	137	mutated	mutate	VBN
cord-263699-gosqpg3k	177	138	.	.	.
cord-263699-gosqpg3k	178	1	Furthermore	furthermore	RB
cord-263699-gosqpg3k	178	2	,	,	,
cord-263699-gosqpg3k	178	3	taking	take	VBG
cord-263699-gosqpg3k	178	4	into	into	IN
cord-263699-gosqpg3k	178	5	account	account	NN
cord-263699-gosqpg3k	178	6	that	that	IN
cord-263699-gosqpg3k	178	7	the	the	DT
cord-263699-gosqpg3k	178	8	expression	expression	NN
cord-263699-gosqpg3k	178	9	of	of	IN
cord-263699-gosqpg3k	178	10	3A	3A	NNP
cord-263699-gosqpg3k	178	11	can	can	MD
cord-263699-gosqpg3k	178	12	inhibit	inhibit	VB
cord-263699-gosqpg3k	178	13	selectively	selectively	RB
cord-263699-gosqpg3k	178	14	some	some	DT
cord-263699-gosqpg3k	178	15	steps	step	NNS
cord-263699-gosqpg3k	178	16	of	of	IN
cord-263699-gosqpg3k	178	17	the	the	DT
cord-263699-gosqpg3k	178	18	secretory	secretory	JJ
cord-263699-gosqpg3k	178	19	pathway	pathway	NN
cord-263699-gosqpg3k	178	20	[	[	-LRB-
cord-263699-gosqpg3k	178	21	105	105	CD
cord-263699-gosqpg3k	178	22	,	,	,
cord-263699-gosqpg3k	178	23	106	106	CD
cord-263699-gosqpg3k	178	24	,	,	,
cord-263699-gosqpg3k	178	25	110	110	CD
cord-263699-gosqpg3k	178	26	]	]	-RRB-
cord-263699-gosqpg3k	178	27	and	and	CC
cord-263699-gosqpg3k	178	28	that	that	DT
cord-263699-gosqpg3k	178	29	overexpression	overexpression	NN
cord-263699-gosqpg3k	178	30	of	of	IN
cord-263699-gosqpg3k	178	31	GBF1	GBF1	NNP
cord-263699-gosqpg3k	178	32	has	have	VBZ
cord-263699-gosqpg3k	178	33	been	be	VBN
cord-263699-gosqpg3k	178	34	shown	show	VBN
cord-263699-gosqpg3k	178	35	to	to	TO
cord-263699-gosqpg3k	178	36	counteract	counteract	VB
cord-263699-gosqpg3k	178	37	these	these	DT
cord-263699-gosqpg3k	178	38	effects	effect	NNS
cord-263699-gosqpg3k	178	39	[	[	-LRB-
cord-263699-gosqpg3k	178	40	105	105	CD
cord-263699-gosqpg3k	178	41	]	]	-RRB-
cord-263699-gosqpg3k	178	42	,	,	,
cord-263699-gosqpg3k	178	43	it	-PRON-	PRP
cord-263699-gosqpg3k	178	44	seems	seem	VBZ
cord-263699-gosqpg3k	178	45	that	that	IN
cord-263699-gosqpg3k	178	46	the	the	DT
cord-263699-gosqpg3k	178	47	interaction	interaction	NN
cord-263699-gosqpg3k	178	48	of	of	IN
cord-263699-gosqpg3k	178	49	3A	3a	CD
cord-263699-gosqpg3k	178	50	with	with	IN
cord-263699-gosqpg3k	178	51	GBF1	GBF1	NNP
cord-263699-gosqpg3k	178	52	is	be	VBZ
cord-263699-gosqpg3k	178	53	essential	essential	JJ
cord-263699-gosqpg3k	178	54	to	to	TO
cord-263699-gosqpg3k	178	55	block	block	VB
cord-263699-gosqpg3k	178	56	the	the	DT
cord-263699-gosqpg3k	178	57	secretory	secretory	JJ
cord-263699-gosqpg3k	178	58	pathway	pathway	NN
cord-263699-gosqpg3k	178	59	,	,	,
cord-263699-gosqpg3k	178	60	rather	rather	RB
cord-263699-gosqpg3k	178	61	than	than	IN
cord-263699-gosqpg3k	178	62	to	to	TO
cord-263699-gosqpg3k	178	63	participate	participate	VB
cord-263699-gosqpg3k	178	64	in	in	IN
cord-263699-gosqpg3k	178	65	the	the	DT
cord-263699-gosqpg3k	178	66	replication	replication	NN
cord-263699-gosqpg3k	178	67	of	of	IN
cord-263699-gosqpg3k	178	68	EV	ev	NN
cord-263699-gosqpg3k	178	69	.	.	.
cord-263699-gosqpg3k	179	1	Therefore	therefore	RB
cord-263699-gosqpg3k	179	2	,	,	,
cord-263699-gosqpg3k	179	3	it	-PRON-	PRP
cord-263699-gosqpg3k	179	4	is	be	VBZ
cord-263699-gosqpg3k	179	5	possible	possible	JJ
cord-263699-gosqpg3k	179	6	that	that	IN
cord-263699-gosqpg3k	179	7	3A	3A	NNP
cord-263699-gosqpg3k	179	8	functions	function	NNS
cord-263699-gosqpg3k	179	9	as	as	IN
cord-263699-gosqpg3k	179	10	a	a	DT
cord-263699-gosqpg3k	179	11	competitive	competitive	JJ
cord-263699-gosqpg3k	179	12	inhibitor	inhibitor	NN
cord-263699-gosqpg3k	179	13	that	that	WDT
cord-263699-gosqpg3k	179	14	binds	bind	VBZ
cord-263699-gosqpg3k	179	15	GBF1	GBF1	NNP
cord-263699-gosqpg3k	179	16	in	in	IN
cord-263699-gosqpg3k	179	17	order	order	NN
cord-263699-gosqpg3k	179	18	to	to	TO
cord-263699-gosqpg3k	179	19	hinder	hinder	VB
cord-263699-gosqpg3k	179	20	its	-PRON-	PRP$
cord-263699-gosqpg3k	179	21	activity	activity	NN
cord-263699-gosqpg3k	179	22	in	in	IN
cord-263699-gosqpg3k	179	23	the	the	DT
cord-263699-gosqpg3k	179	24	secretory	secretory	JJ
cord-263699-gosqpg3k	179	25	pathway	pathway	NN
cord-263699-gosqpg3k	179	26	.	.	.
cord-263699-gosqpg3k	180	1	The	the	DT
cord-263699-gosqpg3k	180	2	relevance	relevance	NN
cord-263699-gosqpg3k	180	3	of	of	IN
cord-263699-gosqpg3k	180	4	the	the	DT
cord-263699-gosqpg3k	180	5	Arf	Arf	NNP
cord-263699-gosqpg3k	180	6	activation	activation	NN
cord-263699-gosqpg3k	180	7	in	in	IN
cord-263699-gosqpg3k	180	8	the	the	DT
cord-263699-gosqpg3k	180	9	replication	replication	NN
cord-263699-gosqpg3k	180	10	cycle	cycle	NN
cord-263699-gosqpg3k	180	11	of	of	IN
cord-263699-gosqpg3k	180	12	EV	EV	NNP
cord-263699-gosqpg3k	180	13	is	be	VBZ
cord-263699-gosqpg3k	180	14	also	also	RB
cord-263699-gosqpg3k	180	15	unclear	unclear	JJ
cord-263699-gosqpg3k	180	16	.	.	.
cord-263699-gosqpg3k	181	1	The	the	DT
cord-263699-gosqpg3k	181	2	depletion	depletion	NN
cord-263699-gosqpg3k	181	3	of	of	IN
cord-263699-gosqpg3k	181	4	Arf	Arf	NNP
cord-263699-gosqpg3k	181	5	proteins	protein	NNS
cord-263699-gosqpg3k	181	6	has	have	VBZ
cord-263699-gosqpg3k	181	7	been	be	VBN
cord-263699-gosqpg3k	181	8	shown	show	VBN
cord-263699-gosqpg3k	181	9	to	to	TO
cord-263699-gosqpg3k	181	10	reduce	reduce	VB
cord-263699-gosqpg3k	181	11	the	the	DT
cord-263699-gosqpg3k	181	12	replication	replication	NN
cord-263699-gosqpg3k	181	13	of	of	IN
cord-263699-gosqpg3k	181	14	EV71	EV71	NNP
cord-263699-gosqpg3k	181	15	,	,	,
cord-263699-gosqpg3k	181	16	CVB4	CVB4	NNP
cord-263699-gosqpg3k	181	17	,	,	,
cord-263699-gosqpg3k	181	18	and	and	CC
cord-263699-gosqpg3k	181	19	CVB3	CVB3	NNPS
cord-263699-gosqpg3k	181	20	[	[	-LRB-
cord-263699-gosqpg3k	181	21	51	51	CD
cord-263699-gosqpg3k	181	22	,	,	,
cord-263699-gosqpg3k	181	23	62	62	CD
cord-263699-gosqpg3k	181	24	,	,	,
cord-263699-gosqpg3k	181	25	64	64	CD
cord-263699-gosqpg3k	181	26	]	]	-RRB-
cord-263699-gosqpg3k	181	27	,	,	,
cord-263699-gosqpg3k	181	28	indicating	indicate	VBG
cord-263699-gosqpg3k	181	29	that	that	IN
cord-263699-gosqpg3k	181	30	these	these	DT
cord-263699-gosqpg3k	181	31	factors	factor	NNS
cord-263699-gosqpg3k	181	32	are	be	VBP
cord-263699-gosqpg3k	181	33	important	important	JJ
cord-263699-gosqpg3k	181	34	for	for	IN
cord-263699-gosqpg3k	181	35	EV	ev	NN
cord-263699-gosqpg3k	181	36	replication	replication	NN
cord-263699-gosqpg3k	181	37	.	.	.
cord-263699-gosqpg3k	182	1	However	however	RB
cord-263699-gosqpg3k	182	2	,	,	,
cord-263699-gosqpg3k	182	3	the	the	DT
cord-263699-gosqpg3k	182	4	expression	expression	NN
cord-263699-gosqpg3k	182	5	of	of	IN
cord-263699-gosqpg3k	182	6	a	a	DT
cord-263699-gosqpg3k	182	7	truncated	truncated	JJ
cord-263699-gosqpg3k	182	8	mutant	mutant	NN
cord-263699-gosqpg3k	182	9	composed	compose	VBN
cord-263699-gosqpg3k	182	10	of	of	IN
cord-263699-gosqpg3k	182	11	the	the	DT
cord-263699-gosqpg3k	182	12	N	n	CD
cord-263699-gosqpg3k	182	13	-	-	HYPH
cord-263699-gosqpg3k	182	14	terminal	terminal	NN
cord-263699-gosqpg3k	182	15	DCB	DCB	NNP
cord-263699-gosqpg3k	182	16	and	and	CC
cord-263699-gosqpg3k	182	17	HUS	HUS	NNP
cord-263699-gosqpg3k	182	18	domains	domain	NNS
cord-263699-gosqpg3k	182	19	of	of	IN
cord-263699-gosqpg3k	182	20	GBF1	GBF1	NNP
cord-263699-gosqpg3k	182	21	,	,	,
cord-263699-gosqpg3k	182	22	but	but	CC
cord-263699-gosqpg3k	182	23	lacking	lack	VBG
cord-263699-gosqpg3k	182	24	the	the	DT
cord-263699-gosqpg3k	182	25	Sec7	Sec7	NNP
cord-263699-gosqpg3k	182	26	domain	domain	NN
cord-263699-gosqpg3k	182	27	,	,	,
cord-263699-gosqpg3k	182	28	has	have	VBZ
cord-263699-gosqpg3k	182	29	been	be	VBN
cord-263699-gosqpg3k	182	30	shown	show	VBN
cord-263699-gosqpg3k	182	31	to	to	TO
cord-263699-gosqpg3k	182	32	be	be	VB
cord-263699-gosqpg3k	182	33	sufficient	sufficient	JJ
cord-263699-gosqpg3k	182	34	for	for	IN
cord-263699-gosqpg3k	182	35	the	the	DT
cord-263699-gosqpg3k	182	36	rescue	rescue	NN
cord-263699-gosqpg3k	182	37	of	of	IN
cord-263699-gosqpg3k	182	38	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	182	39	and	and	CC
cord-263699-gosqpg3k	182	40	CVB3	CVB3	NNP
cord-263699-gosqpg3k	182	41	RNA	RNA	NNP
cord-263699-gosqpg3k	182	42	replication	replication	NN
cord-263699-gosqpg3k	182	43	in	in	IN
cord-263699-gosqpg3k	182	44	the	the	DT
cord-263699-gosqpg3k	182	45	presence	presence	NN
cord-263699-gosqpg3k	182	46	of	of	IN
cord-263699-gosqpg3k	182	47	BFA	BFA	NNP
cord-263699-gosqpg3k	182	48	[	[	-LRB-
cord-263699-gosqpg3k	182	49	59	59	CD
cord-263699-gosqpg3k	182	50	,	,	,
cord-263699-gosqpg3k	182	51	61	61	CD
cord-263699-gosqpg3k	182	52	]	]	-RRB-
cord-263699-gosqpg3k	182	53	.	.	.
cord-263699-gosqpg3k	183	1	Thus	thus	RB
cord-263699-gosqpg3k	183	2	,	,	,
cord-263699-gosqpg3k	183	3	it	-PRON-	PRP
cord-263699-gosqpg3k	183	4	has	have	VBZ
cord-263699-gosqpg3k	183	5	been	be	VBN
cord-263699-gosqpg3k	183	6	proposed	propose	VBN
cord-263699-gosqpg3k	183	7	that	that	IN
cord-263699-gosqpg3k	183	8	although	although	IN
cord-263699-gosqpg3k	183	9	GBF1	GBF1	NNP
cord-263699-gosqpg3k	183	10	is	be	VBZ
cord-263699-gosqpg3k	183	11	essential	essential	JJ
cord-263699-gosqpg3k	183	12	for	for	IN
cord-263699-gosqpg3k	183	13	EV	ev	NN
cord-263699-gosqpg3k	183	14	replication	replication	NN
cord-263699-gosqpg3k	183	15	,	,	,
cord-263699-gosqpg3k	183	16	the	the	DT
cord-263699-gosqpg3k	183	17	increment	increment	NN
cord-263699-gosqpg3k	183	18	of	of	IN
cord-263699-gosqpg3k	183	19	Arf	Arf	NNP
cord-263699-gosqpg3k	183	20	activation	activation	NN
cord-263699-gosqpg3k	183	21	detected	detect	VBN
cord-263699-gosqpg3k	183	22	during	during	IN
cord-263699-gosqpg3k	183	23	infection	infection	NN
cord-263699-gosqpg3k	183	24	of	of	IN
cord-263699-gosqpg3k	183	25	some	some	DT
cord-263699-gosqpg3k	183	26	members	member	NNS
cord-263699-gosqpg3k	183	27	of	of	IN
cord-263699-gosqpg3k	183	28	EV	ev	NN
cord-263699-gosqpg3k	183	29	genus	genus	NN
cord-263699-gosqpg3k	183	30	might	may	MD
cord-263699-gosqpg3k	183	31	be	be	VB
cord-263699-gosqpg3k	183	32	a	a	DT
cord-263699-gosqpg3k	183	33	side	side	NN
cord-263699-gosqpg3k	183	34	effect	effect	NN
cord-263699-gosqpg3k	183	35	produced	produce	VBN
cord-263699-gosqpg3k	183	36	by	by	IN
cord-263699-gosqpg3k	183	37	the	the	DT
cord-263699-gosqpg3k	183	38	increased	increase	VBN
cord-263699-gosqpg3k	183	39	association	association	NN
cord-263699-gosqpg3k	183	40	of	of	IN
cord-263699-gosqpg3k	183	41	GBF1	GBF1	NNP
cord-263699-gosqpg3k	183	42	with	with	IN
cord-263699-gosqpg3k	183	43	membranes	membrane	NNS
cord-263699-gosqpg3k	183	44	[	[	-LRB-
cord-263699-gosqpg3k	183	45	111	111	CD
cord-263699-gosqpg3k	183	46	]	]	-RRB-
cord-263699-gosqpg3k	183	47	.	.	.
cord-263699-gosqpg3k	184	1	These	these	DT
cord-263699-gosqpg3k	184	2	results	result	NNS
cord-263699-gosqpg3k	184	3	led	lead	VBD
cord-263699-gosqpg3k	184	4	to	to	TO
cord-263699-gosqpg3k	184	5	propose	propose	VB
cord-263699-gosqpg3k	184	6	that	that	IN
cord-263699-gosqpg3k	184	7	the	the	DT
cord-263699-gosqpg3k	184	8	N	n	CD
cord-263699-gosqpg3k	184	9	-	-	HYPH
cord-263699-gosqpg3k	184	10	terminus	terminus	NN
cord-263699-gosqpg3k	184	11	of	of	IN
cord-263699-gosqpg3k	184	12	GBF1	GBF1	NNP
cord-263699-gosqpg3k	184	13	might	may	MD
cord-263699-gosqpg3k	184	14	play	play	VB
cord-263699-gosqpg3k	184	15	an	an	DT
cord-263699-gosqpg3k	184	16	essential	essential	JJ
cord-263699-gosqpg3k	184	17	role	role	NN
cord-263699-gosqpg3k	184	18	in	in	IN
cord-263699-gosqpg3k	184	19	RNA	RNA	NNP
cord-263699-gosqpg3k	184	20	replication	replication	NN
cord-263699-gosqpg3k	184	21	by	by	IN
cord-263699-gosqpg3k	184	22	stimulating	stimulate	VBG
cord-263699-gosqpg3k	184	23	the	the	DT
cord-263699-gosqpg3k	184	24	recruitment	recruitment	NN
cord-263699-gosqpg3k	184	25	of	of	IN
cord-263699-gosqpg3k	184	26	cellular	cellular	JJ
cord-263699-gosqpg3k	184	27	factors	factor	NNS
cord-263699-gosqpg3k	184	28	that	that	WDT
cord-263699-gosqpg3k	184	29	are	be	VBP
cord-263699-gosqpg3k	184	30	essential	essential	JJ
cord-263699-gosqpg3k	184	31	for	for	IN
cord-263699-gosqpg3k	184	32	the	the	DT
cord-263699-gosqpg3k	184	33	function	function	NN
cord-263699-gosqpg3k	184	34	of	of	IN
cord-263699-gosqpg3k	184	35	the	the	DT
cord-263699-gosqpg3k	184	36	replication	replication	NN
cord-263699-gosqpg3k	184	37	complexes	complex	NNS
cord-263699-gosqpg3k	184	38	of	of	IN
cord-263699-gosqpg3k	184	39	EV	ev	NN
cord-263699-gosqpg3k	184	40	;	;	:
cord-263699-gosqpg3k	184	41	however	however	RB
cord-263699-gosqpg3k	184	42	,	,	,
cord-263699-gosqpg3k	184	43	the	the	DT
cord-263699-gosqpg3k	184	44	identity	identity	NN
cord-263699-gosqpg3k	184	45	of	of	IN
cord-263699-gosqpg3k	184	46	these	these	DT
cord-263699-gosqpg3k	184	47	effectors	effector	NNS
cord-263699-gosqpg3k	184	48	remains	remain	VBZ
cord-263699-gosqpg3k	184	49	to	to	TO
cord-263699-gosqpg3k	184	50	be	be	VB
cord-263699-gosqpg3k	184	51	elucidated	elucidate	VBN
cord-263699-gosqpg3k	184	52	.	.	.
cord-263699-gosqpg3k	185	1	Recent	recent	JJ
cord-263699-gosqpg3k	185	2	findings	finding	NNS
cord-263699-gosqpg3k	185	3	have	have	VBP
cord-263699-gosqpg3k	185	4	shown	show	VBN
cord-263699-gosqpg3k	185	5	that	that	IN
cord-263699-gosqpg3k	185	6	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	185	7	triggers	trigger	VBZ
cord-263699-gosqpg3k	185	8	the	the	DT
cord-263699-gosqpg3k	185	9	lipid	lipid	NN
cord-263699-gosqpg3k	185	10	membrane	membrane	NN
cord-263699-gosqpg3k	185	11	synthesis	synthesis	NN
cord-263699-gosqpg3k	185	12	of	of	IN
cord-263699-gosqpg3k	185	13	replication	replication	NN
cord-263699-gosqpg3k	185	14	complexes	complex	NNS
cord-263699-gosqpg3k	185	15	by	by	IN
cord-263699-gosqpg3k	185	16	mobilizing	mobilize	VBG
cord-263699-gosqpg3k	185	17	the	the	DT
cord-263699-gosqpg3k	185	18	neutral	neutral	JJ
cord-263699-gosqpg3k	185	19	lipids	lipid	NNS
cord-263699-gosqpg3k	185	20	stored	store	VBN
cord-263699-gosqpg3k	185	21	in	in	IN
cord-263699-gosqpg3k	185	22	LDs	LDs	NNP
cord-263699-gosqpg3k	185	23	,	,	,
cord-263699-gosqpg3k	185	24	in	in	IN
cord-263699-gosqpg3k	185	25	an	an	DT
cord-263699-gosqpg3k	185	26	adipose	adipose	JJ
cord-263699-gosqpg3k	185	27	triglyceride	triglyceride	NN
cord-263699-gosqpg3k	185	28	lipase	lipase	NN
cord-263699-gosqpg3k	185	29	(	(	-LRB-
cord-263699-gosqpg3k	185	30	ATGL	ATGL	NNP
cord-263699-gosqpg3k	185	31	)	)	-RRB-
cord-263699-gosqpg3k	185	32	and	and	CC
cord-263699-gosqpg3k	185	33	hormone	hormone	NN
cord-263699-gosqpg3k	185	34	-	-	HYPH
cord-263699-gosqpg3k	185	35	sensitive	sensitive	JJ
cord-263699-gosqpg3k	185	36	lipase	lipase	NN
cord-263699-gosqpg3k	185	37	(	(	-LRB-
cord-263699-gosqpg3k	185	38	HSL	HSL	NNP
cord-263699-gosqpg3k	185	39	)	)	-RRB-
cord-263699-gosqpg3k	185	40	dependent	dependent	JJ
cord-263699-gosqpg3k	185	41	fashion	fashion	NN
cord-263699-gosqpg3k	185	42	[	[	-LRB-
cord-263699-gosqpg3k	185	43	112	112	CD
cord-263699-gosqpg3k	185	44	]	]	-RRB-
cord-263699-gosqpg3k	185	45	.	.	.
cord-263699-gosqpg3k	186	1	These	these	DT
cord-263699-gosqpg3k	186	2	observations	observation	NNS
cord-263699-gosqpg3k	186	3	,	,	,
cord-263699-gosqpg3k	186	4	together	together	RB
cord-263699-gosqpg3k	186	5	with	with	IN
cord-263699-gosqpg3k	186	6	described	describe	VBN
cord-263699-gosqpg3k	186	7	functions	function	NNS
cord-263699-gosqpg3k	186	8	of	of	IN
cord-263699-gosqpg3k	186	9	GBF1	GBF1	NNP
cord-263699-gosqpg3k	186	10	in	in	IN
cord-263699-gosqpg3k	186	11	LDs	LDs	NNP
cord-263699-gosqpg3k	186	12	morphology	morphology	NN
cord-263699-gosqpg3k	186	13	,	,	,
cord-263699-gosqpg3k	186	14	and	and	CC
cord-263699-gosqpg3k	186	15	its	-PRON-	PRP$
cord-263699-gosqpg3k	186	16	role	role	NN
cord-263699-gosqpg3k	186	17	in	in	IN
cord-263699-gosqpg3k	186	18	prompting	prompt	VBG
cord-263699-gosqpg3k	186	19	the	the	DT
cord-263699-gosqpg3k	186	20	transport	transport	NN
cord-263699-gosqpg3k	186	21	of	of	IN
cord-263699-gosqpg3k	186	22	ATGL	ATGL	NNP
cord-263699-gosqpg3k	186	23	to	to	IN
cord-263699-gosqpg3k	186	24	LDs	LDs	NNP
cord-263699-gosqpg3k	186	25	[	[	-LRB-
cord-263699-gosqpg3k	186	26	42	42	CD
cord-263699-gosqpg3k	186	27	,	,	,
cord-263699-gosqpg3k	186	28	113	113	CD
cord-263699-gosqpg3k	186	29	]	]	-RRB-
cord-263699-gosqpg3k	186	30	,	,	,
cord-263699-gosqpg3k	186	31	seem	seem	VBP
cord-263699-gosqpg3k	186	32	to	to	TO
cord-263699-gosqpg3k	186	33	indicate	indicate	VB
cord-263699-gosqpg3k	186	34	that	that	IN
cord-263699-gosqpg3k	186	35	GBF1	GBF1	NNP
cord-263699-gosqpg3k	186	36	might	may	MD
cord-263699-gosqpg3k	186	37	support	support	VB
cord-263699-gosqpg3k	186	38	the	the	DT
cord-263699-gosqpg3k	186	39	function	function	NN
cord-263699-gosqpg3k	186	40	of	of	IN
cord-263699-gosqpg3k	186	41	EV	ev	NN
cord-263699-gosqpg3k	186	42	replication	replication	NN
cord-263699-gosqpg3k	186	43	complexes	complex	NNS
cord-263699-gosqpg3k	186	44	through	through	IN
cord-263699-gosqpg3k	186	45	regulating	regulate	VBG
cord-263699-gosqpg3k	186	46	the	the	DT
cord-263699-gosqpg3k	186	47	lipid	lipid	NN
cord-263699-gosqpg3k	186	48	flux	flux	NN
cord-263699-gosqpg3k	186	49	from	from	IN
cord-263699-gosqpg3k	186	50	LDs	LDs	NNP
cord-263699-gosqpg3k	186	51	.	.	.
cord-263699-gosqpg3k	187	1	In	in	IN
cord-263699-gosqpg3k	187	2	this	this	DT
cord-263699-gosqpg3k	187	3	regard	regard	NN
cord-263699-gosqpg3k	187	4	,	,	,
cord-263699-gosqpg3k	187	5	it	-PRON-	PRP
cord-263699-gosqpg3k	187	6	has	have	VBZ
cord-263699-gosqpg3k	187	7	been	be	VBN
cord-263699-gosqpg3k	187	8	observed	observe	VBN
cord-263699-gosqpg3k	187	9	that	that	IN
cord-263699-gosqpg3k	187	10	BFA	BFA	NNP
cord-263699-gosqpg3k	187	11	inhibits	inhibit	VBZ
cord-263699-gosqpg3k	187	12	the	the	DT
cord-263699-gosqpg3k	187	13	increment	increment	NN
cord-263699-gosqpg3k	187	14	of	of	IN
cord-263699-gosqpg3k	187	15	lipid	lipid	NN
cord-263699-gosqpg3k	187	16	synthesis	synthesis	NN
cord-263699-gosqpg3k	187	17	induced	induce	VBN
cord-263699-gosqpg3k	187	18	by	by	IN
cord-263699-gosqpg3k	187	19	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	187	20	infection	infection	NN
cord-263699-gosqpg3k	187	21	[	[	-LRB-
cord-263699-gosqpg3k	187	22	99	99	CD
cord-263699-gosqpg3k	187	23	]	]	-RRB-
cord-263699-gosqpg3k	187	24	.	.	.
cord-263699-gosqpg3k	188	1	In	in	IN
cord-263699-gosqpg3k	188	2	contrast	contrast	NN
cord-263699-gosqpg3k	188	3	to	to	IN
cord-263699-gosqpg3k	188	4	the	the	DT
cord-263699-gosqpg3k	188	5	strong	strong	JJ
cord-263699-gosqpg3k	188	6	evidence	evidence	NN
cord-263699-gosqpg3k	188	7	regarding	regard	VBG
cord-263699-gosqpg3k	188	8	the	the	DT
cord-263699-gosqpg3k	188	9	relevance	relevance	NN
cord-263699-gosqpg3k	188	10	of	of	IN
cord-263699-gosqpg3k	188	11	GBF1	GBF1	NNP
cord-263699-gosqpg3k	188	12	for	for	IN
cord-263699-gosqpg3k	188	13	the	the	DT
cord-263699-gosqpg3k	188	14	replication	replication	NN
cord-263699-gosqpg3k	188	15	of	of	IN
cord-263699-gosqpg3k	188	16	several	several	JJ
cord-263699-gosqpg3k	188	17	enteroviruses	enterovirus	NNS
cord-263699-gosqpg3k	188	18	,	,	,
cord-263699-gosqpg3k	188	19	this	this	DT
cord-263699-gosqpg3k	188	20	dependency	dependency	NN
cord-263699-gosqpg3k	188	21	is	be	VBZ
cord-263699-gosqpg3k	188	22	not	not	RB
cord-263699-gosqpg3k	188	23	a	a	DT
cord-263699-gosqpg3k	188	24	common	common	JJ
cord-263699-gosqpg3k	188	25	feature	feature	NN
cord-263699-gosqpg3k	188	26	shared	share	VBN
cord-263699-gosqpg3k	188	27	by	by	IN
cord-263699-gosqpg3k	188	28	all	all	DT
cord-263699-gosqpg3k	188	29	members	member	NNS
cord-263699-gosqpg3k	188	30	of	of	IN
cord-263699-gosqpg3k	188	31	the	the	DT
cord-263699-gosqpg3k	188	32	Picornaviridae	Picornaviridae	NNP
cord-263699-gosqpg3k	188	33	family	family	NN
cord-263699-gosqpg3k	188	34	.	.	.
cord-263699-gosqpg3k	189	1	Encephalomyocarditis	encephalomyocarditis	NN
cord-263699-gosqpg3k	189	2	virus	virus	NN
cord-263699-gosqpg3k	189	3	(	(	-LRB-
cord-263699-gosqpg3k	189	4	EMCV	EMCV	NNP
cord-263699-gosqpg3k	189	5	,	,	,
cord-263699-gosqpg3k	189	6	member	member	NN
cord-263699-gosqpg3k	189	7	of	of	IN
cord-263699-gosqpg3k	189	8	the	the	DT
cord-263699-gosqpg3k	189	9	Cardiovirus	Cardiovirus	NNP
cord-263699-gosqpg3k	189	10	genus	genus	NN
cord-263699-gosqpg3k	189	11	)	)	-RRB-
cord-263699-gosqpg3k	189	12	,	,	,
cord-263699-gosqpg3k	189	13	the	the	DT
cord-263699-gosqpg3k	189	14	foot	foot	NN
cord-263699-gosqpg3k	189	15	-	-	HYPH
cord-263699-gosqpg3k	189	16	and	and	CC
cord-263699-gosqpg3k	189	17	-	-	HYPH
cord-263699-gosqpg3k	189	18	mouth	mouth	NN
cord-263699-gosqpg3k	189	19	disease	disease	NN
cord-263699-gosqpg3k	189	20	virus	virus	NN
cord-263699-gosqpg3k	189	21	(	(	-LRB-
cord-263699-gosqpg3k	189	22	FMDV	FMDV	NNP
cord-263699-gosqpg3k	189	23	,	,	,
cord-263699-gosqpg3k	189	24	member	member	NN
cord-263699-gosqpg3k	189	25	of	of	IN
cord-263699-gosqpg3k	189	26	the	the	DT
cord-263699-gosqpg3k	189	27	Aphthovirus	Aphthovirus	NNP
cord-263699-gosqpg3k	189	28	genus	genus	NN
cord-263699-gosqpg3k	189	29	)	)	-RRB-
cord-263699-gosqpg3k	189	30	,	,	,
cord-263699-gosqpg3k	189	31	as	as	RB
cord-263699-gosqpg3k	189	32	well	well	RB
cord-263699-gosqpg3k	189	33	as	as	IN
cord-263699-gosqpg3k	189	34	the	the	DT
cord-263699-gosqpg3k	189	35	Aichi	Aichi	NNP
cord-263699-gosqpg3k	189	36	virus	virus	NN
cord-263699-gosqpg3k	189	37	(	(	-LRB-
cord-263699-gosqpg3k	189	38	AiV	AiV	NNP
cord-263699-gosqpg3k	189	39	,	,	,
cord-263699-gosqpg3k	189	40	member	member	NN
cord-263699-gosqpg3k	189	41	of	of	IN
cord-263699-gosqpg3k	189	42	Kobuvirus	Kobuvirus	NNP
cord-263699-gosqpg3k	189	43	genus	genus	NN
cord-263699-gosqpg3k	189	44	)	)	-RRB-
cord-263699-gosqpg3k	189	45	have	have	VBP
cord-263699-gosqpg3k	189	46	been	be	VBN
cord-263699-gosqpg3k	189	47	shown	show	VBN
cord-263699-gosqpg3k	189	48	to	to	TO
cord-263699-gosqpg3k	189	49	be	be	VB
cord-263699-gosqpg3k	189	50	resistant	resistant	JJ
cord-263699-gosqpg3k	189	51	to	to	IN
cord-263699-gosqpg3k	189	52	the	the	DT
cord-263699-gosqpg3k	189	53	effects	effect	NNS
cord-263699-gosqpg3k	189	54	of	of	IN
cord-263699-gosqpg3k	189	55	BFA	BFA	NNP
cord-263699-gosqpg3k	189	56	,	,	,
cord-263699-gosqpg3k	189	57	indicating	indicate	VBG
cord-263699-gosqpg3k	189	58	that	that	IN
cord-263699-gosqpg3k	189	59	GBF1	GBF1	NNP
cord-263699-gosqpg3k	189	60	is	be	VBZ
cord-263699-gosqpg3k	189	61	not	not	RB
cord-263699-gosqpg3k	189	62	involved	involve	VBN
cord-263699-gosqpg3k	189	63	in	in	IN
cord-263699-gosqpg3k	189	64	their	-PRON-	PRP$
cord-263699-gosqpg3k	189	65	replication	replication	NN
cord-263699-gosqpg3k	189	66	cycle	cycle	NN
cord-263699-gosqpg3k	189	67	[	[	-LRB-
cord-263699-gosqpg3k	189	68	102	102	CD
cord-263699-gosqpg3k	189	69	,	,	,
cord-263699-gosqpg3k	189	70	103	103	CD
cord-263699-gosqpg3k	189	71	,	,	,
cord-263699-gosqpg3k	189	72	114	114	CD
cord-263699-gosqpg3k	189	73	,	,	,
cord-263699-gosqpg3k	189	74	115	115	CD
cord-263699-gosqpg3k	189	75	]	]	-RRB-
cord-263699-gosqpg3k	189	76	.	.	.
cord-263699-gosqpg3k	190	1	On	on	IN
cord-263699-gosqpg3k	190	2	the	the	DT
cord-263699-gosqpg3k	190	3	other	other	JJ
cord-263699-gosqpg3k	190	4	hand	hand	NN
cord-263699-gosqpg3k	190	5	,	,	,
cord-263699-gosqpg3k	190	6	the	the	DT
cord-263699-gosqpg3k	190	7	dependency	dependency	NN
cord-263699-gosqpg3k	190	8	on	on	IN
cord-263699-gosqpg3k	190	9	GBF1	GBF1	NNP
cord-263699-gosqpg3k	190	10	does	do	VBZ
cord-263699-gosqpg3k	190	11	not	not	RB
cord-263699-gosqpg3k	190	12	seem	seem	VB
cord-263699-gosqpg3k	190	13	to	to	TO
cord-263699-gosqpg3k	190	14	be	be	VB
cord-263699-gosqpg3k	190	15	limited	limit	VBN
cord-263699-gosqpg3k	190	16	to	to	IN
cord-263699-gosqpg3k	190	17	the	the	DT
cord-263699-gosqpg3k	190	18	EV	ev	NN
cord-263699-gosqpg3k	190	19	genus	genus	NN
cord-263699-gosqpg3k	190	20	,	,	,
cord-263699-gosqpg3k	190	21	since	since	IN
cord-263699-gosqpg3k	190	22	the	the	DT
cord-263699-gosqpg3k	190	23	replication	replication	NN
cord-263699-gosqpg3k	190	24	of	of	IN
cord-263699-gosqpg3k	190	25	parechovirus	parechovirus	NNP
cord-263699-gosqpg3k	190	26	1	1	CD
cord-263699-gosqpg3k	190	27	(	(	-LRB-
cord-263699-gosqpg3k	190	28	ParV1	ParV1	NNP
cord-263699-gosqpg3k	190	29	,	,	,
cord-263699-gosqpg3k	190	30	member	member	NN
cord-263699-gosqpg3k	190	31	of	of	IN
cord-263699-gosqpg3k	190	32	the	the	DT
cord-263699-gosqpg3k	190	33	Parechovirus	Parechovirus	NNP
cord-263699-gosqpg3k	190	34	genus	genus	NN
cord-263699-gosqpg3k	190	35	)	)	-RRB-
cord-263699-gosqpg3k	190	36	is	be	VBZ
cord-263699-gosqpg3k	190	37	partially	partially	RB
cord-263699-gosqpg3k	190	38	sensitive	sensitive	JJ
cord-263699-gosqpg3k	190	39	to	to	IN
cord-263699-gosqpg3k	190	40	BFA	BFA	NNP
cord-263699-gosqpg3k	190	41	[	[	-LRB-
cord-263699-gosqpg3k	190	42	102	102	CD
cord-263699-gosqpg3k	190	43	]	]	-RRB-
cord-263699-gosqpg3k	190	44	.	.	.
cord-263699-gosqpg3k	191	1	This	this	DT
cord-263699-gosqpg3k	191	2	genus	genus	NN
cord-263699-gosqpg3k	191	3	includes	include	VBZ
cord-263699-gosqpg3k	191	4	a	a	DT
cord-263699-gosqpg3k	191	5	large	large	JJ
cord-263699-gosqpg3k	191	6	number	number	NN
cord-263699-gosqpg3k	191	7	of	of	IN
cord-263699-gosqpg3k	191	8	mosquito	mosquito	NN
cord-263699-gosqpg3k	191	9	-	-	HYPH
cord-263699-gosqpg3k	191	10	borne	bear	VBN
cord-263699-gosqpg3k	191	11	viruses	virus	NNS
cord-263699-gosqpg3k	191	12	that	that	WDT
cord-263699-gosqpg3k	191	13	can	can	MD
cord-263699-gosqpg3k	191	14	infect	infect	VB
cord-263699-gosqpg3k	191	15	mammals	mammal	NNS
cord-263699-gosqpg3k	191	16	,	,	,
cord-263699-gosqpg3k	191	17	birds	bird	NNS
cord-263699-gosqpg3k	191	18	,	,	,
cord-263699-gosqpg3k	191	19	fish	fish	NN
cord-263699-gosqpg3k	191	20	,	,	,
cord-263699-gosqpg3k	191	21	reptiles	reptile	NNS
cord-263699-gosqpg3k	191	22	,	,	,
cord-263699-gosqpg3k	191	23	and	and	CC
cord-263699-gosqpg3k	191	24	amphibians	amphibian	NNS
cord-263699-gosqpg3k	191	25	.	.	.
cord-263699-gosqpg3k	192	1	Alphaviruses	alphavirus	NNS
cord-263699-gosqpg3k	192	2	consist	consist	VBP
cord-263699-gosqpg3k	192	3	of	of	IN
cord-263699-gosqpg3k	192	4	enveloped	envelop	VBN
cord-263699-gosqpg3k	192	5	viral	viral	JJ
cord-263699-gosqpg3k	192	6	particles	particle	NNS
cord-263699-gosqpg3k	192	7	that	that	WDT
cord-263699-gosqpg3k	192	8	contain	contain	VBP
cord-263699-gosqpg3k	192	9	a	a	DT
cord-263699-gosqpg3k	192	10	single	single	RB
cord-263699-gosqpg3k	192	11	-	-	HYPH
cord-263699-gosqpg3k	192	12	stranded	strand	VBN
cord-263699-gosqpg3k	192	13	positive	positive	JJ
cord-263699-gosqpg3k	192	14	-	-	HYPH
cord-263699-gosqpg3k	192	15	sense	sense	NN
cord-263699-gosqpg3k	192	16	RNA	RNA	NNP
cord-263699-gosqpg3k	192	17	genome	genome	NN
cord-263699-gosqpg3k	192	18	that	that	WDT
cord-263699-gosqpg3k	192	19	encodes	encode	VBZ
cord-263699-gosqpg3k	192	20	two	two	CD
cord-263699-gosqpg3k	192	21	ORFs	orf	NNS
cord-263699-gosqpg3k	192	22	.	.	.
cord-263699-gosqpg3k	193	1	The	the	DT
cord-263699-gosqpg3k	193	2	first	first	JJ
cord-263699-gosqpg3k	193	3	ORF	ORF	NNP
cord-263699-gosqpg3k	193	4	directs	direct	VBZ
cord-263699-gosqpg3k	193	5	the	the	DT
cord-263699-gosqpg3k	193	6	synthesis	synthesis	NN
cord-263699-gosqpg3k	193	7	of	of	IN
cord-263699-gosqpg3k	193	8	four	four	CD
cord-263699-gosqpg3k	193	9	non	non	JJ
cord-263699-gosqpg3k	193	10	-	-	JJ
cord-263699-gosqpg3k	193	11	structural	structural	JJ
cord-263699-gosqpg3k	193	12	proteins	protein	NNS
cord-263699-gosqpg3k	193	13	(	(	-LRB-
cord-263699-gosqpg3k	193	14	nsP1	nsp1	NN
cord-263699-gosqpg3k	193	15	-	-	HYPH
cord-263699-gosqpg3k	193	16	4	4	CD
cord-263699-gosqpg3k	193	17	)	)	-RRB-
cord-263699-gosqpg3k	193	18	,	,	,
cord-263699-gosqpg3k	193	19	whereas	whereas	IN
cord-263699-gosqpg3k	193	20	the	the	DT
cord-263699-gosqpg3k	193	21	second	second	JJ
cord-263699-gosqpg3k	193	22	ORF	ORF	NNP
cord-263699-gosqpg3k	193	23	codes	code	NNS
cord-263699-gosqpg3k	193	24	for	for	IN
cord-263699-gosqpg3k	193	25	the	the	DT
cord-263699-gosqpg3k	193	26	structural	structural	JJ
cord-263699-gosqpg3k	193	27	capsid	capsid	NN
cord-263699-gosqpg3k	193	28	protein	protein	NN
cord-263699-gosqpg3k	193	29	(	(	-LRB-
cord-263699-gosqpg3k	193	30	CP	CP	NNP
cord-263699-gosqpg3k	193	31	)	)	-RRB-
cord-263699-gosqpg3k	193	32	and	and	CC
cord-263699-gosqpg3k	193	33	two	two	CD
cord-263699-gosqpg3k	193	34	surface	surface	NN
cord-263699-gosqpg3k	193	35	envelope	envelope	NN
cord-263699-gosqpg3k	193	36	glycoproteins	glycoprotein	NNS
cord-263699-gosqpg3k	193	37	(	(	-LRB-
cord-263699-gosqpg3k	193	38	E1	E1	NNP
cord-263699-gosqpg3k	193	39	and	and	CC
cord-263699-gosqpg3k	193	40	E2	E2	NNP
cord-263699-gosqpg3k	193	41	)	)	-RRB-
cord-263699-gosqpg3k	193	42	[	[	-LRB-
cord-263699-gosqpg3k	193	43	116	116	CD
cord-263699-gosqpg3k	193	44	]	]	-RRB-
cord-263699-gosqpg3k	193	45	.	.	.
cord-263699-gosqpg3k	194	1	Once	once	RB
cord-263699-gosqpg3k	194	2	in	in	IN
cord-263699-gosqpg3k	194	3	the	the	DT
cord-263699-gosqpg3k	194	4	cytoplasm	cytoplasm	NN
cord-263699-gosqpg3k	194	5	,	,	,
cord-263699-gosqpg3k	194	6	the	the	DT
cord-263699-gosqpg3k	194	7	viral	viral	JJ
cord-263699-gosqpg3k	194	8	genome	genome	NN
cord-263699-gosqpg3k	194	9	is	be	VBZ
cord-263699-gosqpg3k	194	10	translated	translate	VBN
cord-263699-gosqpg3k	194	11	to	to	TO
cord-263699-gosqpg3k	194	12	produce	produce	VB
cord-263699-gosqpg3k	194	13	a	a	DT
cord-263699-gosqpg3k	194	14	single	single	JJ
cord-263699-gosqpg3k	194	15	polyprotein	polyprotein	NN
cord-263699-gosqpg3k	194	16	formed	form	VBN
cord-263699-gosqpg3k	194	17	by	by	IN
cord-263699-gosqpg3k	194	18	the	the	DT
cord-263699-gosqpg3k	194	19	four	four	CD
cord-263699-gosqpg3k	194	20	nonstructural	nonstructural	JJ
cord-263699-gosqpg3k	194	21	proteins	protein	NNS
cord-263699-gosqpg3k	194	22	.	.	.
cord-263699-gosqpg3k	195	1	The	the	DT
cord-263699-gosqpg3k	195	2	auto	auto	NN
cord-263699-gosqpg3k	195	3	-	-	HYPH
cord-263699-gosqpg3k	195	4	proteolytic	proteolytic	JJ
cord-263699-gosqpg3k	195	5	processing	processing	NN
cord-263699-gosqpg3k	195	6	of	of	IN
cord-263699-gosqpg3k	195	7	this	this	DT
cord-263699-gosqpg3k	195	8	polyprotein	polyprotein	NN
cord-263699-gosqpg3k	195	9	renders	render	VBZ
cord-263699-gosqpg3k	195	10	the	the	DT
cord-263699-gosqpg3k	195	11	individual	individual	JJ
cord-263699-gosqpg3k	195	12	nsP1	nsp1	NN
cord-263699-gosqpg3k	195	13	-	-	HYPH
cord-263699-gosqpg3k	195	14	4	4	CD
cord-263699-gosqpg3k	195	15	proteins	protein	NNS
cord-263699-gosqpg3k	195	16	that	that	WDT
cord-263699-gosqpg3k	195	17	assemble	assemble	VBP
cord-263699-gosqpg3k	195	18	to	to	TO
cord-263699-gosqpg3k	195	19	form	form	VB
cord-263699-gosqpg3k	195	20	a	a	DT
cord-263699-gosqpg3k	195	21	replicase	replicase	NN
cord-263699-gosqpg3k	195	22	complex	complex	NN
cord-263699-gosqpg3k	195	23	.	.	.
cord-263699-gosqpg3k	196	1	The	the	DT
cord-263699-gosqpg3k	196	2	replicase	replicase	NN
cord-263699-gosqpg3k	196	3	complex	complex	NN
cord-263699-gosqpg3k	196	4	,	,	,
cord-263699-gosqpg3k	196	5	together	together	RB
cord-263699-gosqpg3k	196	6	with	with	IN
cord-263699-gosqpg3k	196	7	the	the	DT
cord-263699-gosqpg3k	196	8	genomic	genomic	JJ
cord-263699-gosqpg3k	196	9	RNA	RNA	NNP
cord-263699-gosqpg3k	196	10	and	and	CC
cord-263699-gosqpg3k	196	11	host	host	NN
cord-263699-gosqpg3k	196	12	proteins	protein	NNS
cord-263699-gosqpg3k	196	13	,	,	,
cord-263699-gosqpg3k	196	14	then	then	RB
cord-263699-gosqpg3k	196	15	assemble	assemble	VB
cord-263699-gosqpg3k	196	16	at	at	IN
cord-263699-gosqpg3k	196	17	the	the	DT
cord-263699-gosqpg3k	196	18	plasma	plasma	NN
cord-263699-gosqpg3k	196	19	membrane	membrane	NN
cord-263699-gosqpg3k	196	20	to	to	TO
cord-263699-gosqpg3k	196	21	form	form	VB
cord-263699-gosqpg3k	196	22	viral	viral	JJ
cord-263699-gosqpg3k	196	23	replication	replication	NN
cord-263699-gosqpg3k	196	24	compartments	compartment	NNS
cord-263699-gosqpg3k	196	25	called	call	VBN
cord-263699-gosqpg3k	196	26	spherules	spherule	NNS
cord-263699-gosqpg3k	196	27	that	that	WDT
cord-263699-gosqpg3k	196	28	direct	direct	VBP
cord-263699-gosqpg3k	196	29	the	the	DT
cord-263699-gosqpg3k	196	30	replication	replication	NN
cord-263699-gosqpg3k	196	31	and	and	CC
cord-263699-gosqpg3k	196	32	transcription	transcription	NN
cord-263699-gosqpg3k	196	33	of	of	IN
cord-263699-gosqpg3k	196	34	the	the	DT
cord-263699-gosqpg3k	196	35	viral	viral	JJ
cord-263699-gosqpg3k	196	36	RNA	RNA	NNP
cord-263699-gosqpg3k	196	37	.	.	.
cord-263699-gosqpg3k	197	1	Furthermore	furthermore	RB
cord-263699-gosqpg3k	197	2	,	,	,
cord-263699-gosqpg3k	197	3	as	as	IN
cord-263699-gosqpg3k	197	4	the	the	DT
cord-263699-gosqpg3k	197	5	infection	infection	NN
cord-263699-gosqpg3k	197	6	progresses	progress	VBZ
cord-263699-gosqpg3k	197	7	,	,	,
cord-263699-gosqpg3k	197	8	the	the	DT
cord-263699-gosqpg3k	197	9	internalization	internalization	NN
cord-263699-gosqpg3k	197	10	of	of	IN
cord-263699-gosqpg3k	197	11	the	the	DT
cord-263699-gosqpg3k	197	12	spherules	spherule	NNS
cord-263699-gosqpg3k	197	13	from	from	IN
cord-263699-gosqpg3k	197	14	the	the	DT
cord-263699-gosqpg3k	197	15	plasma	plasma	NN
cord-263699-gosqpg3k	197	16	membrane	membrane	NN
cord-263699-gosqpg3k	197	17	has	have	VBZ
cord-263699-gosqpg3k	197	18	been	be	VBN
cord-263699-gosqpg3k	197	19	shown	show	VBN
cord-263699-gosqpg3k	197	20	to	to	TO
cord-263699-gosqpg3k	197	21	create	create	VB
cord-263699-gosqpg3k	197	22	large	large	JJ
cord-263699-gosqpg3k	197	23	cytopathic	cytopathic	JJ
cord-263699-gosqpg3k	197	24	type	type	NN
cord-263699-gosqpg3k	197	25	1vacuoles	1vacuole	NNS
cord-263699-gosqpg3k	197	26	(	(	-LRB-
cord-263699-gosqpg3k	197	27	CPV-1	CPV-1	NNP
cord-263699-gosqpg3k	197	28	)	)	-RRB-
cord-263699-gosqpg3k	197	29	that	that	WDT
cord-263699-gosqpg3k	197	30	can	can	MD
cord-263699-gosqpg3k	197	31	also	also	RB
cord-263699-gosqpg3k	197	32	direct	direct	VB
cord-263699-gosqpg3k	197	33	the	the	DT
cord-263699-gosqpg3k	197	34	replication	replication	NN
cord-263699-gosqpg3k	197	35	and	and	CC
cord-263699-gosqpg3k	197	36	transcription	transcription	NN
cord-263699-gosqpg3k	197	37	of	of	IN
cord-263699-gosqpg3k	197	38	viral	viral	JJ
cord-263699-gosqpg3k	197	39	RNA	RNA	NNP
cord-263699-gosqpg3k	197	40	.	.	.
cord-263699-gosqpg3k	198	1	Either	either	CC
cord-263699-gosqpg3k	198	2	from	from	IN
cord-263699-gosqpg3k	198	3	spherules	spherule	NNS
cord-263699-gosqpg3k	198	4	or	or	CC
cord-263699-gosqpg3k	198	5	CPV-1	CPV-1	NNP
cord-263699-gosqpg3k	198	6	,	,	,
cord-263699-gosqpg3k	198	7	a	a	DT
cord-263699-gosqpg3k	198	8	subgenomic	subgenomic	NNP
cord-263699-gosqpg3k	198	9	RNA	RNA	NNP
cord-263699-gosqpg3k	198	10	is	be	VBZ
cord-263699-gosqpg3k	198	11	transcribed	transcribe	VBN
cord-263699-gosqpg3k	198	12	from	from	IN
cord-263699-gosqpg3k	198	13	the	the	DT
cord-263699-gosqpg3k	198	14	second	second	JJ
cord-263699-gosqpg3k	198	15	ORF	ORF	NNP
cord-263699-gosqpg3k	198	16	to	to	TO
cord-263699-gosqpg3k	198	17	produce	produce	VB
cord-263699-gosqpg3k	198	18	a	a	DT
cord-263699-gosqpg3k	198	19	single	single	JJ
cord-263699-gosqpg3k	198	20	polyprotein	polyprotein	NN
cord-263699-gosqpg3k	198	21	composed	compose	VBN
cord-263699-gosqpg3k	198	22	of	of	IN
cord-263699-gosqpg3k	198	23	the	the	DT
cord-263699-gosqpg3k	198	24	structural	structural	JJ
cord-263699-gosqpg3k	198	25	proteins	protein	NNS
cord-263699-gosqpg3k	198	26	CP	CP	NNP
cord-263699-gosqpg3k	198	27	,	,	,
cord-263699-gosqpg3k	198	28	E2	E2	NNP
cord-263699-gosqpg3k	198	29	,	,	,
cord-263699-gosqpg3k	198	30	and	and	CC
cord-263699-gosqpg3k	198	31	E1	E1	NNP
cord-263699-gosqpg3k	198	32	.	.	.
cord-263699-gosqpg3k	199	1	The	the	DT
cord-263699-gosqpg3k	199	2	auto	auto	NN
cord-263699-gosqpg3k	199	3	proteolysis	proteolysis	NN
cord-263699-gosqpg3k	199	4	of	of	IN
cord-263699-gosqpg3k	199	5	this	this	DT
cord-263699-gosqpg3k	199	6	polyprotein	polyprotein	NN
cord-263699-gosqpg3k	199	7	releases	release	VBZ
cord-263699-gosqpg3k	199	8	CP	CP	NNP
cord-263699-gosqpg3k	199	9	in	in	IN
cord-263699-gosqpg3k	199	10	the	the	DT
cord-263699-gosqpg3k	199	11	cytosol	cytosol	NN
cord-263699-gosqpg3k	199	12	and	and	CC
cord-263699-gosqpg3k	199	13	permits	permit	VBZ
cord-263699-gosqpg3k	199	14	the	the	DT
cord-263699-gosqpg3k	199	15	translocation	translocation	NN
cord-263699-gosqpg3k	199	16	of	of	IN
cord-263699-gosqpg3k	199	17	E1	E1	NNP
cord-263699-gosqpg3k	199	18	and	and	CC
cord-263699-gosqpg3k	199	19	E2	E2	NNP
cord-263699-gosqpg3k	199	20	into	into	IN
cord-263699-gosqpg3k	199	21	the	the	DT
cord-263699-gosqpg3k	199	22	ER	ER	NNP
cord-263699-gosqpg3k	199	23	,	,	,
cord-263699-gosqpg3k	199	24	where	where	WRB
cord-263699-gosqpg3k	199	25	they	-PRON-	PRP
cord-263699-gosqpg3k	199	26	are	be	VBP
cord-263699-gosqpg3k	199	27	post	post	JJ
cord-263699-gosqpg3k	199	28	translationally	translationally	RB
cord-263699-gosqpg3k	199	29	modified	modify	VBN
cord-263699-gosqpg3k	199	30	to	to	TO
cord-263699-gosqpg3k	199	31	yield	yield	VB
cord-263699-gosqpg3k	199	32	the	the	DT
cord-263699-gosqpg3k	199	33	final	final	JJ
cord-263699-gosqpg3k	199	34	glycoproteins	glycoprotein	NNS
cord-263699-gosqpg3k	199	35	that	that	WDT
cord-263699-gosqpg3k	199	36	are	be	VBP
cord-263699-gosqpg3k	199	37	then	then	RB
cord-263699-gosqpg3k	199	38	transported	transport	VBN
cord-263699-gosqpg3k	199	39	by	by	IN
cord-263699-gosqpg3k	199	40	the	the	DT
cord-263699-gosqpg3k	199	41	exocytic	exocytic	JJ
cord-263699-gosqpg3k	199	42	pathway	pathway	NN
cord-263699-gosqpg3k	199	43	to	to	IN
cord-263699-gosqpg3k	199	44	the	the	DT
cord-263699-gosqpg3k	199	45	plasma	plasma	NN
cord-263699-gosqpg3k	199	46	membrane	membrane	NN
cord-263699-gosqpg3k	199	47	.	.	.
cord-263699-gosqpg3k	200	1	Concomitant	concomitant	JJ
cord-263699-gosqpg3k	200	2	with	with	IN
cord-263699-gosqpg3k	200	3	these	these	DT
cord-263699-gosqpg3k	200	4	processes	process	NNS
cord-263699-gosqpg3k	200	5	,	,	,
cord-263699-gosqpg3k	200	6	the	the	DT
cord-263699-gosqpg3k	200	7	formation	formation	NN
cord-263699-gosqpg3k	200	8	of	of	IN
cord-263699-gosqpg3k	200	9	new	new	JJ
cord-263699-gosqpg3k	200	10	icosahedral	icosahedral	JJ
cord-263699-gosqpg3k	200	11	nucleocapsids	nucleocapsid	NNS
cord-263699-gosqpg3k	200	12	occurs	occur	VBZ
cord-263699-gosqpg3k	200	13	in	in	IN
cord-263699-gosqpg3k	200	14	the	the	DT
cord-263699-gosqpg3k	200	15	replication	replication	NN
cord-263699-gosqpg3k	200	16	complexes	complex	NNS
cord-263699-gosqpg3k	200	17	that	that	WDT
cord-263699-gosqpg3k	200	18	associate	associate	VBP
cord-263699-gosqpg3k	200	19	to	to	IN
cord-263699-gosqpg3k	200	20	plasma	plasma	NN
cord-263699-gosqpg3k	200	21	membrane	membrane	NN
cord-263699-gosqpg3k	200	22	sites	site	NNS
cord-263699-gosqpg3k	200	23	decorated	decorate	VBN
cord-263699-gosqpg3k	200	24	with	with	IN
cord-263699-gosqpg3k	200	25	E2	E2	NNP
cord-263699-gosqpg3k	200	26	/	/	SYM
cord-263699-gosqpg3k	200	27	E1	E1	NNP
cord-263699-gosqpg3k	200	28	and	and	CC
cord-263699-gosqpg3k	200	29	then	then	RB
cord-263699-gosqpg3k	200	30	bud	bud	VB
cord-263699-gosqpg3k	200	31	to	to	IN
cord-263699-gosqpg3k	200	32	the	the	DT
cord-263699-gosqpg3k	200	33	extracellular	extracellular	JJ
cord-263699-gosqpg3k	200	34	medium	medium	NN
cord-263699-gosqpg3k	200	35	,	,	,
cord-263699-gosqpg3k	200	36	producing	produce	VBG
cord-263699-gosqpg3k	200	37	the	the	DT
cord-263699-gosqpg3k	200	38	mature	mature	JJ
cord-263699-gosqpg3k	200	39	enveloped	envelop	VBN
cord-263699-gosqpg3k	200	40	particles	particle	NNS
cord-263699-gosqpg3k	200	41	.	.	.
cord-263699-gosqpg3k	201	1	[	[	-LRB-
cord-263699-gosqpg3k	201	2	116	116	CD
cord-263699-gosqpg3k	201	3	,	,	,
cord-263699-gosqpg3k	201	4	117	117	CD
cord-263699-gosqpg3k	201	5	]	]	-RRB-
cord-263699-gosqpg3k	201	6	.	.	.
cord-263699-gosqpg3k	202	1	Given	give	VBN
cord-263699-gosqpg3k	202	2	the	the	DT
cord-263699-gosqpg3k	202	3	involvement	involvement	NN
cord-263699-gosqpg3k	202	4	of	of	IN
cord-263699-gosqpg3k	202	5	the	the	DT
cord-263699-gosqpg3k	202	6	secretory	secretory	JJ
cord-263699-gosqpg3k	202	7	pathway	pathway	NN
cord-263699-gosqpg3k	202	8	in	in	IN
cord-263699-gosqpg3k	202	9	the	the	DT
cord-263699-gosqpg3k	202	10	proper	proper	JJ
cord-263699-gosqpg3k	202	11	processing	processing	NN
cord-263699-gosqpg3k	202	12	and	and	CC
cord-263699-gosqpg3k	202	13	transport	transport	NN
cord-263699-gosqpg3k	202	14	of	of	IN
cord-263699-gosqpg3k	202	15	E1	e1	NN
cord-263699-gosqpg3k	202	16	/	/	SYM
cord-263699-gosqpg3k	202	17	E2	E2	NNP
cord-263699-gosqpg3k	202	18	to	to	IN
cord-263699-gosqpg3k	202	19	the	the	DT
cord-263699-gosqpg3k	202	20	plasma	plasma	NN
cord-263699-gosqpg3k	202	21	membrane	membrane	NN
cord-263699-gosqpg3k	202	22	,	,	,
cord-263699-gosqpg3k	202	23	this	this	DT
cord-263699-gosqpg3k	202	24	transport	transport	NN
cord-263699-gosqpg3k	202	25	has	have	VBZ
cord-263699-gosqpg3k	202	26	been	be	VBN
cord-263699-gosqpg3k	202	27	thought	think	VBN
cord-263699-gosqpg3k	202	28	to	to	TO
cord-263699-gosqpg3k	202	29	be	be	VB
cord-263699-gosqpg3k	202	30	important	important	JJ
cord-263699-gosqpg3k	202	31	only	only	RB
cord-263699-gosqpg3k	202	32	for	for	IN
cord-263699-gosqpg3k	202	33	virus	virus	NN
cord-263699-gosqpg3k	202	34	particle	particle	NN
cord-263699-gosqpg3k	202	35	maturation	maturation	NN
cord-263699-gosqpg3k	202	36	.	.	.
cord-263699-gosqpg3k	203	1	However	however	RB
cord-263699-gosqpg3k	203	2	,	,	,
cord-263699-gosqpg3k	203	3	in	in	IN
cord-263699-gosqpg3k	203	4	recent	recent	JJ
cord-263699-gosqpg3k	203	5	years	year	NNS
cord-263699-gosqpg3k	203	6	it	-PRON-	PRP
cord-263699-gosqpg3k	203	7	was	be	VBD
cord-263699-gosqpg3k	203	8	found	find	VBN
cord-263699-gosqpg3k	203	9	that	that	IN
cord-263699-gosqpg3k	203	10	the	the	DT
cord-263699-gosqpg3k	203	11	inhibition	inhibition	NN
cord-263699-gosqpg3k	203	12	of	of	IN
cord-263699-gosqpg3k	203	13	protein	protein	NN
cord-263699-gosqpg3k	203	14	transport	transport	NN
cord-263699-gosqpg3k	203	15	by	by	IN
cord-263699-gosqpg3k	203	16	BFA	BFA	NNP
cord-263699-gosqpg3k	203	17	or	or	CC
cord-263699-gosqpg3k	203	18	GCA	GCA	NNP
cord-263699-gosqpg3k	203	19	could	could	MD
cord-263699-gosqpg3k	203	20	disturb	disturb	VB
cord-263699-gosqpg3k	203	21	the	the	DT
cord-263699-gosqpg3k	203	22	RNA	RNA	NNP
cord-263699-gosqpg3k	203	23	replication	replication	NN
cord-263699-gosqpg3k	203	24	and	and	CC
cord-263699-gosqpg3k	203	25	protein	protein	NN
cord-263699-gosqpg3k	203	26	synthesis	synthesis	NN
cord-263699-gosqpg3k	203	27	of	of	IN
cord-263699-gosqpg3k	203	28	Sindbis	Sindbis	NNP
cord-263699-gosqpg3k	203	29	virus	virus	NN
cord-263699-gosqpg3k	203	30	(	(	-LRB-
cord-263699-gosqpg3k	203	31	SINV	SINV	NNP
cord-263699-gosqpg3k	203	32	)	)	-RRB-
cord-263699-gosqpg3k	204	1	[	[	-LRB-
cord-263699-gosqpg3k	204	2	51	51	CD
cord-263699-gosqpg3k	204	3	,	,	,
cord-263699-gosqpg3k	204	4	67	67	CD
cord-263699-gosqpg3k	204	5	]	]	-RRB-
cord-263699-gosqpg3k	204	6	,	,	,
cord-263699-gosqpg3k	204	7	the	the	DT
cord-263699-gosqpg3k	204	8	prototype	prototype	NN
cord-263699-gosqpg3k	204	9	member	member	NN
cord-263699-gosqpg3k	204	10	of	of	IN
cord-263699-gosqpg3k	204	11	this	this	DT
cord-263699-gosqpg3k	204	12	genus	genus	NN
cord-263699-gosqpg3k	204	13	,	,	,
cord-263699-gosqpg3k	204	14	as	as	RB
cord-263699-gosqpg3k	204	15	well	well	RB
cord-263699-gosqpg3k	204	16	as	as	IN
cord-263699-gosqpg3k	204	17	of	of	IN
cord-263699-gosqpg3k	204	18	chikungunya	chikungunya	NN
cord-263699-gosqpg3k	204	19	virus	virus	NN
cord-263699-gosqpg3k	204	20	(	(	-LRB-
cord-263699-gosqpg3k	204	21	CHIKV	CHIKV	NNP
cord-263699-gosqpg3k	204	22	)	)	-RRB-
cord-263699-gosqpg3k	205	1	[	[	-LRB-
cord-263699-gosqpg3k	205	2	66	66	CD
cord-263699-gosqpg3k	205	3	]	]	-RRB-
cord-263699-gosqpg3k	205	4	.	.	.
cord-263699-gosqpg3k	206	1	This	this	DT
cord-263699-gosqpg3k	206	2	alteration	alteration	NN
cord-263699-gosqpg3k	206	3	was	be	VBD
cord-263699-gosqpg3k	206	4	found	find	VBN
cord-263699-gosqpg3k	206	5	to	to	TO
cord-263699-gosqpg3k	206	6	be	be	VB
cord-263699-gosqpg3k	206	7	associated	associate	VBN
cord-263699-gosqpg3k	206	8	with	with	IN
cord-263699-gosqpg3k	206	9	a	a	DT
cord-263699-gosqpg3k	206	10	post	post	NN
cord-263699-gosqpg3k	206	11	entry	entry	NN
cord-263699-gosqpg3k	206	12	virus	virus	NN
cord-263699-gosqpg3k	206	13	replication	replication	NN
cord-263699-gosqpg3k	206	14	step	step	NN
cord-263699-gosqpg3k	206	15	that	that	WDT
cord-263699-gosqpg3k	206	16	depends	depend	VBZ
cord-263699-gosqpg3k	206	17	on	on	IN
cord-263699-gosqpg3k	206	18	the	the	DT
cord-263699-gosqpg3k	206	19	activity	activity	NN
cord-263699-gosqpg3k	206	20	of	of	IN
cord-263699-gosqpg3k	206	21	GBF1	GBF1	NNP
cord-263699-gosqpg3k	206	22	,	,	,
cord-263699-gosqpg3k	206	23	since	since	IN
cord-263699-gosqpg3k	206	24	depletion	depletion	NN
cord-263699-gosqpg3k	206	25	of	of	IN
cord-263699-gosqpg3k	206	26	this	this	DT
cord-263699-gosqpg3k	206	27	factor	factor	NN
cord-263699-gosqpg3k	206	28	was	be	VBD
cord-263699-gosqpg3k	206	29	sufficient	sufficient	JJ
cord-263699-gosqpg3k	206	30	to	to	TO
cord-263699-gosqpg3k	206	31	reduce	reduce	VB
cord-263699-gosqpg3k	206	32	the	the	DT
cord-263699-gosqpg3k	206	33	viral	viral	JJ
cord-263699-gosqpg3k	206	34	RNA	RNA	NNP
cord-263699-gosqpg3k	206	35	replication	replication	NN
cord-263699-gosqpg3k	206	36	[	[	-LRB-
cord-263699-gosqpg3k	206	37	66	66	CD
cord-263699-gosqpg3k	206	38	]	]	-RRB-
cord-263699-gosqpg3k	206	39	.	.	.
cord-263699-gosqpg3k	207	1	Given	give	VBN
cord-263699-gosqpg3k	207	2	that	that	IN
cord-263699-gosqpg3k	207	3	alphavirus	alphavirus	NNP
cord-263699-gosqpg3k	207	4	replication	replication	NN
cord-263699-gosqpg3k	207	5	has	have	VBZ
cord-263699-gosqpg3k	207	6	been	be	VBN
cord-263699-gosqpg3k	207	7	shown	show	VBN
cord-263699-gosqpg3k	207	8	to	to	TO
cord-263699-gosqpg3k	207	9	induce	induce	VB
cord-263699-gosqpg3k	207	10	the	the	DT
cord-263699-gosqpg3k	207	11	formation	formation	NN
cord-263699-gosqpg3k	207	12	of	of	IN
cord-263699-gosqpg3k	207	13	membrane	membrane	NN
cord-263699-gosqpg3k	207	14	vesicles	vesicle	NNS
cord-263699-gosqpg3k	207	15	in	in	IN
cord-263699-gosqpg3k	207	16	order	order	NN
cord-263699-gosqpg3k	207	17	to	to	TO
cord-263699-gosqpg3k	207	18	create	create	VB
cord-263699-gosqpg3k	207	19	the	the	DT
cord-263699-gosqpg3k	207	20	viral	viral	JJ
cord-263699-gosqpg3k	207	21	replication	replication	NN
cord-263699-gosqpg3k	207	22	complexes	complex	NNS
cord-263699-gosqpg3k	207	23	(	(	-LRB-
cord-263699-gosqpg3k	207	24	spherules	spherule	NNS
cord-263699-gosqpg3k	207	25	and	and	CC
cord-263699-gosqpg3k	207	26	CPV-1	CPV-1	NNP
cord-263699-gosqpg3k	207	27	)	)	-RRB-
cord-263699-gosqpg3k	207	28	that	that	WDT
cord-263699-gosqpg3k	207	29	direct	direct	VBP
cord-263699-gosqpg3k	207	30	the	the	DT
cord-263699-gosqpg3k	207	31	synthesis	synthesis	NN
cord-263699-gosqpg3k	207	32	of	of	IN
cord-263699-gosqpg3k	207	33	the	the	DT
cord-263699-gosqpg3k	207	34	viral	viral	JJ
cord-263699-gosqpg3k	207	35	RNA	RNA	NNP
cord-263699-gosqpg3k	207	36	,	,	,
cord-263699-gosqpg3k	207	37	these	these	DT
cord-263699-gosqpg3k	207	38	results	result	NNS
cord-263699-gosqpg3k	207	39	led	lead	VBD
cord-263699-gosqpg3k	207	40	to	to	TO
cord-263699-gosqpg3k	207	41	propose	propose	VB
cord-263699-gosqpg3k	207	42	that	that	IN
cord-263699-gosqpg3k	207	43	the	the	DT
cord-263699-gosqpg3k	207	44	function	function	NN
cord-263699-gosqpg3k	207	45	of	of	IN
cord-263699-gosqpg3k	207	46	GBF1	GBF1	NNP
cord-263699-gosqpg3k	207	47	could	could	MD
cord-263699-gosqpg3k	207	48	be	be	VB
cord-263699-gosqpg3k	207	49	to	to	TO
cord-263699-gosqpg3k	207	50	facilitate	facilitate	VB
cord-263699-gosqpg3k	207	51	the	the	DT
cord-263699-gosqpg3k	207	52	efficient	efficient	JJ
cord-263699-gosqpg3k	207	53	replication	replication	NN
cord-263699-gosqpg3k	207	54	of	of	IN
cord-263699-gosqpg3k	207	55	the	the	DT
cord-263699-gosqpg3k	207	56	alphavirus	alphavirus	NNP
cord-263699-gosqpg3k	207	57	RNA	RNA	NNP
cord-263699-gosqpg3k	207	58	genome	genome	NN
cord-263699-gosqpg3k	207	59	by	by	IN
cord-263699-gosqpg3k	207	60	promoting	promote	VBG
cord-263699-gosqpg3k	207	61	the	the	DT
cord-263699-gosqpg3k	207	62	formation	formation	NN
cord-263699-gosqpg3k	207	63	of	of	IN
cord-263699-gosqpg3k	207	64	the	the	DT
cord-263699-gosqpg3k	207	65	membrane	membrane	NN
cord-263699-gosqpg3k	207	66	vesicles	vesicle	NNS
cord-263699-gosqpg3k	207	67	required	require	VBN
cord-263699-gosqpg3k	207	68	for	for	IN
cord-263699-gosqpg3k	207	69	this	this	DT
cord-263699-gosqpg3k	207	70	process	process	NN
cord-263699-gosqpg3k	207	71	[	[	-LRB-
cord-263699-gosqpg3k	207	72	67	67	CD
cord-263699-gosqpg3k	207	73	]	]	-RRB-
cord-263699-gosqpg3k	207	74	.	.	.
cord-263699-gosqpg3k	208	1	In	in	IN
cord-263699-gosqpg3k	208	2	support	support	NN
cord-263699-gosqpg3k	208	3	of	of	IN
cord-263699-gosqpg3k	208	4	this	this	DT
cord-263699-gosqpg3k	208	5	model	model	NN
cord-263699-gosqpg3k	208	6	,	,	,
cord-263699-gosqpg3k	208	7	it	-PRON-	PRP
cord-263699-gosqpg3k	208	8	has	have	VBZ
cord-263699-gosqpg3k	208	9	been	be	VBN
cord-263699-gosqpg3k	208	10	found	find	VBN
cord-263699-gosqpg3k	208	11	that	that	IN
cord-263699-gosqpg3k	208	12	the	the	DT
cord-263699-gosqpg3k	208	13	alphavirus	alphavirus	NNP
cord-263699-gosqpg3k	208	14	RNA	RNA	NNP
cord-263699-gosqpg3k	208	15	replication	replication	NN
cord-263699-gosqpg3k	208	16	depends	depend	VBZ
cord-263699-gosqpg3k	208	17	on	on	IN
cord-263699-gosqpg3k	208	18	the	the	DT
cord-263699-gosqpg3k	208	19	presence	presence	NN
cord-263699-gosqpg3k	208	20	of	of	IN
cord-263699-gosqpg3k	208	21	Arf1	Arf1	NNP
cord-263699-gosqpg3k	208	22	,	,	,
cord-263699-gosqpg3k	208	23	Arf3	Arf3	NNP
cord-263699-gosqpg3k	208	24	,	,	,
cord-263699-gosqpg3k	208	25	Arf4	Arf4	NNP
cord-263699-gosqpg3k	208	26	,	,	,
cord-263699-gosqpg3k	208	27	and	and	CC
cord-263699-gosqpg3k	208	28	Arf5	Arf5	NNP
cord-263699-gosqpg3k	208	29	[	[	-LRB-
cord-263699-gosqpg3k	208	30	51	51	CD
cord-263699-gosqpg3k	208	31	,	,	,
cord-263699-gosqpg3k	208	32	66	66	CD
cord-263699-gosqpg3k	208	33	]	]	-RRB-
cord-263699-gosqpg3k	208	34	,	,	,
cord-263699-gosqpg3k	208	35	as	as	RB
cord-263699-gosqpg3k	208	36	well	well	RB
cord-263699-gosqpg3k	208	37	as	as	IN
cord-263699-gosqpg3k	208	38	on	on	IN
cord-263699-gosqpg3k	208	39	a	a	DT
cord-263699-gosqpg3k	208	40	functional	functional	JJ
cord-263699-gosqpg3k	208	41	COPI	COPI	NNP
cord-263699-gosqpg3k	208	42	complex	complex	JJ
cord-263699-gosqpg3k	208	43	[	[	-LRB-
cord-263699-gosqpg3k	208	44	66	66	CD
cord-263699-gosqpg3k	208	45	]	]	-RRB-
cord-263699-gosqpg3k	208	46	.	.	.
cord-263699-gosqpg3k	209	1	Thus	thus	RB
cord-263699-gosqpg3k	209	2	,	,	,
cord-263699-gosqpg3k	209	3	these	these	DT
cord-263699-gosqpg3k	209	4	results	result	NNS
cord-263699-gosqpg3k	209	5	indicate	indicate	VBP
cord-263699-gosqpg3k	209	6	that	that	IN
cord-263699-gosqpg3k	209	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	209	8	might	may	MD
cord-263699-gosqpg3k	209	9	induce	induce	VB
cord-263699-gosqpg3k	209	10	the	the	DT
cord-263699-gosqpg3k	209	11	formation	formation	NN
cord-263699-gosqpg3k	209	12	of	of	IN
cord-263699-gosqpg3k	209	13	membrane	membrane	NN
cord-263699-gosqpg3k	209	14	vesicles	vesicle	NNS
cord-263699-gosqpg3k	209	15	through	through	IN
cord-263699-gosqpg3k	209	16	the	the	DT
cord-263699-gosqpg3k	209	17	activation	activation	NN
cord-263699-gosqpg3k	209	18	of	of	IN
cord-263699-gosqpg3k	209	19	the	the	DT
cord-263699-gosqpg3k	209	20	COPI	COPI	NNP
cord-263699-gosqpg3k	209	21	transport	transport	NN
cord-263699-gosqpg3k	209	22	mediated	mediate	VBN
cord-263699-gosqpg3k	209	23	by	by	IN
cord-263699-gosqpg3k	209	24	different	different	JJ
cord-263699-gosqpg3k	209	25	Arf	Arf	NNP
cord-263699-gosqpg3k	209	26	proteins	protein	NNS
cord-263699-gosqpg3k	209	27	.	.	.
cord-263699-gosqpg3k	210	1	In	in	IN
cord-263699-gosqpg3k	210	2	agreement	agreement	NN
cord-263699-gosqpg3k	210	3	with	with	IN
cord-263699-gosqpg3k	210	4	the	the	DT
cord-263699-gosqpg3k	210	5	importance	importance	NN
cord-263699-gosqpg3k	210	6	of	of	IN
cord-263699-gosqpg3k	210	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	210	8	early	early	RB
cord-263699-gosqpg3k	210	9	in	in	IN
cord-263699-gosqpg3k	210	10	infection	infection	NN
cord-263699-gosqpg3k	210	11	,	,	,
cord-263699-gosqpg3k	210	12	it	-PRON-	PRP
cord-263699-gosqpg3k	210	13	was	be	VBD
cord-263699-gosqpg3k	210	14	found	find	VBN
cord-263699-gosqpg3k	210	15	that	that	IN
cord-263699-gosqpg3k	210	16	the	the	DT
cord-263699-gosqpg3k	210	17	inhibitory	inhibitory	JJ
cord-263699-gosqpg3k	210	18	effect	effect	NN
cord-263699-gosqpg3k	210	19	of	of	IN
cord-263699-gosqpg3k	210	20	BFA	BFA	NNP
cord-263699-gosqpg3k	210	21	on	on	IN
cord-263699-gosqpg3k	210	22	the	the	DT
cord-263699-gosqpg3k	210	23	replication	replication	NN
cord-263699-gosqpg3k	210	24	SINV	SINV	NNP
cord-263699-gosqpg3k	210	25	is	be	VBZ
cord-263699-gosqpg3k	210	26	lost	lose	VBN
cord-263699-gosqpg3k	210	27	when	when	WRB
cord-263699-gosqpg3k	210	28	this	this	DT
cord-263699-gosqpg3k	210	29	drug	drug	NN
cord-263699-gosqpg3k	210	30	is	be	VBZ
cord-263699-gosqpg3k	210	31	added	add	VBN
cord-263699-gosqpg3k	210	32	at	at	IN
cord-263699-gosqpg3k	210	33	late	late	JJ
cord-263699-gosqpg3k	210	34	times	time	NNS
cord-263699-gosqpg3k	210	35	post	post	NN
cord-263699-gosqpg3k	210	36	infection	infection	NN
cord-263699-gosqpg3k	210	37	.	.	.
cord-263699-gosqpg3k	211	1	Moreover	moreover	RB
cord-263699-gosqpg3k	211	2	,	,	,
cord-263699-gosqpg3k	211	3	these	these	DT
cord-263699-gosqpg3k	211	4	data	datum	NNS
cord-263699-gosqpg3k	211	5	also	also	RB
cord-263699-gosqpg3k	211	6	suggest	suggest	VBP
cord-263699-gosqpg3k	211	7	that	that	IN
cord-263699-gosqpg3k	211	8	the	the	DT
cord-263699-gosqpg3k	211	9	activity	activity	NN
cord-263699-gosqpg3k	211	10	of	of	IN
cord-263699-gosqpg3k	211	11	GBF1	GBF1	NNP
cord-263699-gosqpg3k	211	12	is	be	VBZ
cord-263699-gosqpg3k	211	13	dispensable	dispensable	JJ
cord-263699-gosqpg3k	211	14	for	for	IN
cord-263699-gosqpg3k	211	15	the	the	DT
cord-263699-gosqpg3k	211	16	function	function	NN
cord-263699-gosqpg3k	211	17	of	of	IN
cord-263699-gosqpg3k	211	18	the	the	DT
cord-263699-gosqpg3k	211	19	alphavirus	alphavirus	NNP
cord-263699-gosqpg3k	211	20	replication	replication	NN
cord-263699-gosqpg3k	211	21	complexes	complex	NNS
cord-263699-gosqpg3k	211	22	since	since	IN
cord-263699-gosqpg3k	211	23	BFA	BFA	NNP
cord-263699-gosqpg3k	211	24	does	do	VBZ
cord-263699-gosqpg3k	211	25	not	not	RB
cord-263699-gosqpg3k	211	26	affect	affect	VB
cord-263699-gosqpg3k	211	27	the	the	DT
cord-263699-gosqpg3k	211	28	replication	replication	NN
cord-263699-gosqpg3k	211	29	of	of	IN
cord-263699-gosqpg3k	211	30	the	the	DT
cord-263699-gosqpg3k	211	31	viral	viral	JJ
cord-263699-gosqpg3k	211	32	RNA	RNA	NNP
cord-263699-gosqpg3k	211	33	once	once	IN
cord-263699-gosqpg3k	211	34	these	these	DT
cord-263699-gosqpg3k	211	35	organelles	organelle	NNS
cord-263699-gosqpg3k	211	36	are	be	VBP
cord-263699-gosqpg3k	211	37	formed	form	VBN
cord-263699-gosqpg3k	211	38	[	[	-LRB-
cord-263699-gosqpg3k	211	39	67	67	CD
cord-263699-gosqpg3k	211	40	,	,	,
cord-263699-gosqpg3k	211	41	118	118	CD
cord-263699-gosqpg3k	211	42	]	]	-RRB-
cord-263699-gosqpg3k	211	43	.	.	.
cord-263699-gosqpg3k	212	1	On	on	IN
cord-263699-gosqpg3k	212	2	the	the	DT
cord-263699-gosqpg3k	212	3	other	other	JJ
cord-263699-gosqpg3k	212	4	hand	hand	NN
cord-263699-gosqpg3k	212	5	,	,	,
cord-263699-gosqpg3k	212	6	taking	take	VBG
cord-263699-gosqpg3k	212	7	into	into	IN
cord-263699-gosqpg3k	212	8	account	account	NN
cord-263699-gosqpg3k	212	9	that	that	IN
cord-263699-gosqpg3k	212	10	Arf4	Arf4	NNP
cord-263699-gosqpg3k	212	11	and	and	CC
cord-263699-gosqpg3k	212	12	Arf5	Arf5	NNP
cord-263699-gosqpg3k	212	13	participate	participate	NN
cord-263699-gosqpg3k	212	14	in	in	IN
cord-263699-gosqpg3k	212	15	maintaining	maintain	VBG
cord-263699-gosqpg3k	212	16	the	the	DT
cord-263699-gosqpg3k	212	17	LD	LD	NNP
cord-263699-gosqpg3k	212	18	morphology	morphology	NN
cord-263699-gosqpg3k	212	19	,	,	,
cord-263699-gosqpg3k	212	20	but	but	CC
cord-263699-gosqpg3k	212	21	are	be	VBP
cord-263699-gosqpg3k	212	22	not	not	RB
cord-263699-gosqpg3k	212	23	important	important	JJ
cord-263699-gosqpg3k	212	24	for	for	IN
cord-263699-gosqpg3k	212	25	protein	protein	NN
cord-263699-gosqpg3k	212	26	transport	transport	NN
cord-263699-gosqpg3k	212	27	[	[	-LRB-
cord-263699-gosqpg3k	212	28	91	91	CD
cord-263699-gosqpg3k	212	29	]	]	-RRB-
cord-263699-gosqpg3k	212	30	,	,	,
cord-263699-gosqpg3k	212	31	the	the	DT
cord-263699-gosqpg3k	212	32	involvement	involvement	NN
cord-263699-gosqpg3k	212	33	of	of	IN
cord-263699-gosqpg3k	212	34	these	these	DT
cord-263699-gosqpg3k	212	35	Arf	Arf	NNP
cord-263699-gosqpg3k	212	36	proteins	protein	NNS
cord-263699-gosqpg3k	212	37	in	in	IN
cord-263699-gosqpg3k	212	38	alphavirus	alphavirus	NNP
cord-263699-gosqpg3k	212	39	RNA	RNA	NNP
cord-263699-gosqpg3k	212	40	replication	replication	NN
cord-263699-gosqpg3k	212	41	might	may	MD
cord-263699-gosqpg3k	212	42	suggest	suggest	VB
cord-263699-gosqpg3k	212	43	that	that	IN
cord-263699-gosqpg3k	212	44	GBF1	GBF1	NNP
cord-263699-gosqpg3k	212	45	and	and	CC
cord-263699-gosqpg3k	212	46	COPI	COPI	NNP
cord-263699-gosqpg3k	212	47	could	could	MD
cord-263699-gosqpg3k	212	48	also	also	RB
cord-263699-gosqpg3k	212	49	participate	participate	VB
cord-263699-gosqpg3k	212	50	in	in	IN
cord-263699-gosqpg3k	212	51	the	the	DT
cord-263699-gosqpg3k	212	52	viral	viral	JJ
cord-263699-gosqpg3k	212	53	RNA	RNA	NNP
cord-263699-gosqpg3k	212	54	replication	replication	NN
cord-263699-gosqpg3k	212	55	through	through	IN
cord-263699-gosqpg3k	212	56	the	the	DT
cord-263699-gosqpg3k	212	57	function	function	NN
cord-263699-gosqpg3k	212	58	of	of	IN
cord-263699-gosqpg3k	212	59	LDs	LDs	NNP
cord-263699-gosqpg3k	212	60	.	.	.
cord-263699-gosqpg3k	213	1	Although	although	IN
cord-263699-gosqpg3k	213	2	the	the	DT
cord-263699-gosqpg3k	213	3	possible	possible	JJ
cord-263699-gosqpg3k	213	4	relation	relation	NN
cord-263699-gosqpg3k	213	5	between	between	IN
cord-263699-gosqpg3k	213	6	LDs	LDs	NNP
cord-263699-gosqpg3k	213	7	and	and	CC
cord-263699-gosqpg3k	213	8	alphavirus	alphavirus	NNP
cord-263699-gosqpg3k	213	9	replication	replication	NN
cord-263699-gosqpg3k	213	10	has	have	VBZ
cord-263699-gosqpg3k	213	11	never	never	RB
cord-263699-gosqpg3k	213	12	been	be	VBN
cord-263699-gosqpg3k	213	13	tested	test	VBN
cord-263699-gosqpg3k	213	14	in	in	IN
cord-263699-gosqpg3k	213	15	mammalian	mammalian	JJ
cord-263699-gosqpg3k	213	16	cells	cell	NNS
cord-263699-gosqpg3k	213	17	,	,	,
cord-263699-gosqpg3k	213	18	the	the	DT
cord-263699-gosqpg3k	213	19	finding	finding	NN
cord-263699-gosqpg3k	213	20	that	that	IN
cord-263699-gosqpg3k	213	21	SINV	SINV	NNP
cord-263699-gosqpg3k	213	22	infection	infection	NN
cord-263699-gosqpg3k	213	23	induces	induce	VBZ
cord-263699-gosqpg3k	213	24	the	the	DT
cord-263699-gosqpg3k	213	25	accumulation	accumulation	NN
cord-263699-gosqpg3k	213	26	of	of	IN
cord-263699-gosqpg3k	213	27	LDs	LDs	NNP
cord-263699-gosqpg3k	213	28	in	in	IN
cord-263699-gosqpg3k	213	29	mosquito	mosquito	NN
cord-263699-gosqpg3k	213	30	Aag2	Aag2	NNP
cord-263699-gosqpg3k	213	31	cells	cell	NNS
cord-263699-gosqpg3k	213	32	as	as	RB
cord-263699-gosqpg3k	213	33	well	well	RB
cord-263699-gosqpg3k	213	34	as	as	IN
cord-263699-gosqpg3k	213	35	in	in	IN
cord-263699-gosqpg3k	213	36	the	the	DT
cord-263699-gosqpg3k	213	37	midgut	midgut	NN
cord-263699-gosqpg3k	213	38	of	of	IN
cord-263699-gosqpg3k	213	39	Aedes	Aedes	NNP
cord-263699-gosqpg3k	213	40	aegypti	aegypti	NN
cord-263699-gosqpg3k	213	41	females	female	NNS
cord-263699-gosqpg3k	213	42	[	[	-LRB-
cord-263699-gosqpg3k	213	43	119	119	CD
cord-263699-gosqpg3k	213	44	]	]	-RRB-
cord-263699-gosqpg3k	213	45	seems	seem	VBZ
cord-263699-gosqpg3k	213	46	to	to	TO
cord-263699-gosqpg3k	213	47	support	support	VB
cord-263699-gosqpg3k	213	48	the	the	DT
cord-263699-gosqpg3k	213	49	idea	idea	NN
cord-263699-gosqpg3k	213	50	that	that	IN
cord-263699-gosqpg3k	213	51	alphavirus	alphavirus	NNP
cord-263699-gosqpg3k	213	52	might	may	MD
cord-263699-gosqpg3k	213	53	rely	rely	VB
cord-263699-gosqpg3k	213	54	on	on	IN
cord-263699-gosqpg3k	213	55	LDs	LDs	NNP
cord-263699-gosqpg3k	213	56	for	for	IN
cord-263699-gosqpg3k	213	57	its	-PRON-	PRP$
cord-263699-gosqpg3k	213	58	replication	replication	NN
cord-263699-gosqpg3k	213	59	.	.	.
cord-263699-gosqpg3k	214	1	The	the	DT
cord-263699-gosqpg3k	214	2	family	family	NN
cord-263699-gosqpg3k	214	3	Hepeviridae	Hepeviridae	NNP
cord-263699-gosqpg3k	214	4	englobes	englobes	VB
cord-263699-gosqpg3k	214	5	a	a	DT
cord-263699-gosqpg3k	214	6	group	group	NN
cord-263699-gosqpg3k	214	7	of	of	IN
cord-263699-gosqpg3k	214	8	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	214	9	E	E	NNP
cord-263699-gosqpg3k	214	10	viruses	virus	NNS
cord-263699-gosqpg3k	214	11	(	(	-LRB-
cord-263699-gosqpg3k	214	12	HEV	HEV	NNP
cord-263699-gosqpg3k	214	13	)	)	-RRB-
cord-263699-gosqpg3k	214	14	that	that	WDT
cord-263699-gosqpg3k	214	15	are	be	VBP
cord-263699-gosqpg3k	214	16	non	non	JJ
cord-263699-gosqpg3k	214	17	-	-	JJ
cord-263699-gosqpg3k	214	18	enveloped	enveloped	JJ
cord-263699-gosqpg3k	214	19	and	and	CC
cord-263699-gosqpg3k	214	20	contain	contain	VBP
cord-263699-gosqpg3k	214	21	a	a	DT
cord-263699-gosqpg3k	214	22	positive	positive	JJ
cord-263699-gosqpg3k	214	23	-	-	HYPH
cord-263699-gosqpg3k	214	24	sense	sense	NN
cord-263699-gosqpg3k	214	25	single	single	JJ
cord-263699-gosqpg3k	214	26	-	-	HYPH
cord-263699-gosqpg3k	214	27	stranded	strand	VBN
cord-263699-gosqpg3k	214	28	RNA	RNA	NNP
cord-263699-gosqpg3k	214	29	genome	genome	NN
cord-263699-gosqpg3k	214	30	that	that	WDT
cord-263699-gosqpg3k	214	31	contains	contain	VBZ
cord-263699-gosqpg3k	214	32	two	two	CD
cord-263699-gosqpg3k	214	33	ORFs	orf	NNS
cord-263699-gosqpg3k	214	34	.	.	.
cord-263699-gosqpg3k	215	1	The	the	DT
cord-263699-gosqpg3k	215	2	first	first	JJ
cord-263699-gosqpg3k	215	3	ORF	ORF	NNP
cord-263699-gosqpg3k	215	4	encodes	encode	VBZ
cord-263699-gosqpg3k	215	5	a	a	DT
cord-263699-gosqpg3k	215	6	non	non	JJ
cord-263699-gosqpg3k	215	7	-	-	JJ
cord-263699-gosqpg3k	215	8	structural	structural	JJ
cord-263699-gosqpg3k	215	9	polyprotein	polyprotein	NN
cord-263699-gosqpg3k	215	10	(	(	-LRB-
cord-263699-gosqpg3k	215	11	ORF1	ORF1	NNP
cord-263699-gosqpg3k	215	12	protein	protein	NN
cord-263699-gosqpg3k	215	13	)	)	-RRB-
cord-263699-gosqpg3k	215	14	that	that	WDT
cord-263699-gosqpg3k	215	15	exhibits	exhibit	VBZ
cord-263699-gosqpg3k	215	16	several	several	JJ
cord-263699-gosqpg3k	215	17	functions	function	NNS
cord-263699-gosqpg3k	215	18	,	,	,
cord-263699-gosqpg3k	215	19	such	such	JJ
cord-263699-gosqpg3k	215	20	as	as	IN
cord-263699-gosqpg3k	215	21	methyltransferase	methyltransferase	NN
cord-263699-gosqpg3k	215	22	,	,	,
cord-263699-gosqpg3k	215	23	protease	protease	NN
cord-263699-gosqpg3k	215	24	,	,	,
cord-263699-gosqpg3k	215	25	RNA	RNA	NNP
cord-263699-gosqpg3k	215	26	helicase	helicase	NNP
cord-263699-gosqpg3k	215	27	,	,	,
cord-263699-gosqpg3k	215	28	and	and	CC
cord-263699-gosqpg3k	215	29	RdRp	RdRp	NNP
cord-263699-gosqpg3k	215	30	,	,	,
cord-263699-gosqpg3k	215	31	while	while	IN
cord-263699-gosqpg3k	215	32	the	the	DT
cord-263699-gosqpg3k	215	33	second	second	JJ
cord-263699-gosqpg3k	215	34	ORF	ORF	NNP
cord-263699-gosqpg3k	215	35	codes	code	NNS
cord-263699-gosqpg3k	215	36	for	for	IN
cord-263699-gosqpg3k	215	37	the	the	DT
cord-263699-gosqpg3k	215	38	capsid	capsid	NN
cord-263699-gosqpg3k	215	39	protein	protein	NN
cord-263699-gosqpg3k	215	40	(	(	-LRB-
cord-263699-gosqpg3k	215	41	CP	CP	NNP
cord-263699-gosqpg3k	215	42	)	)	-RRB-
cord-263699-gosqpg3k	215	43	.	.	.
cord-263699-gosqpg3k	216	1	Due	due	IN
cord-263699-gosqpg3k	216	2	to	to	IN
cord-263699-gosqpg3k	216	3	the	the	DT
cord-263699-gosqpg3k	216	4	low	low	JJ
cord-263699-gosqpg3k	216	5	efficiency	efficiency	NN
cord-263699-gosqpg3k	216	6	of	of	IN
cord-263699-gosqpg3k	216	7	these	these	DT
cord-263699-gosqpg3k	216	8	viruses	virus	NNS
cord-263699-gosqpg3k	216	9	to	to	TO
cord-263699-gosqpg3k	216	10	grow	grow	VB
cord-263699-gosqpg3k	216	11	in	in	IN
cord-263699-gosqpg3k	216	12	cell	cell	NN
cord-263699-gosqpg3k	216	13	culture	culture	NN
cord-263699-gosqpg3k	216	14	,	,	,
cord-263699-gosqpg3k	216	15	their	-PRON-	PRP$
cord-263699-gosqpg3k	216	16	replication	replication	NN
cord-263699-gosqpg3k	216	17	process	process	NN
cord-263699-gosqpg3k	216	18	is	be	VBZ
cord-263699-gosqpg3k	216	19	poorly	poorly	RB
cord-263699-gosqpg3k	216	20	understood	understand	VBN
cord-263699-gosqpg3k	216	21	,	,	,
cord-263699-gosqpg3k	216	22	although	although	IN
cord-263699-gosqpg3k	216	23	it	-PRON-	PRP
cord-263699-gosqpg3k	216	24	has	have	VBZ
cord-263699-gosqpg3k	216	25	been	be	VBN
cord-263699-gosqpg3k	216	26	proposed	propose	VBN
cord-263699-gosqpg3k	216	27	that	that	IN
cord-263699-gosqpg3k	216	28	it	-PRON-	PRP
cord-263699-gosqpg3k	216	29	might	may	MD
cord-263699-gosqpg3k	216	30	be	be	VB
cord-263699-gosqpg3k	216	31	similar	similar	JJ
cord-263699-gosqpg3k	216	32	to	to	IN
cord-263699-gosqpg3k	216	33	that	that	DT
cord-263699-gosqpg3k	216	34	of	of	IN
cord-263699-gosqpg3k	216	35	togaviruses	togaviruse	NNS
cord-263699-gosqpg3k	216	36	[	[	-LRB-
cord-263699-gosqpg3k	216	37	120	120	CD
cord-263699-gosqpg3k	216	38	]	]	-RRB-
cord-263699-gosqpg3k	216	39	.	.	.
cord-263699-gosqpg3k	217	1	In	in	IN
cord-263699-gosqpg3k	217	2	fact	fact	NN
cord-263699-gosqpg3k	217	3	,	,	,
cord-263699-gosqpg3k	217	4	a	a	DT
cord-263699-gosqpg3k	217	5	recent	recent	JJ
cord-263699-gosqpg3k	217	6	report	report	NN
cord-263699-gosqpg3k	217	7	revealed	reveal	VBD
cord-263699-gosqpg3k	217	8	that	that	IN
cord-263699-gosqpg3k	217	9	similar	similar	JJ
cord-263699-gosqpg3k	217	10	to	to	IN
cord-263699-gosqpg3k	217	11	viruses	virus	NNS
cord-263699-gosqpg3k	217	12	in	in	IN
cord-263699-gosqpg3k	217	13	the	the	DT
cord-263699-gosqpg3k	217	14	Togaviridae	Togaviridae	NNP
cord-263699-gosqpg3k	217	15	family	family	NN
cord-263699-gosqpg3k	217	16	,	,	,
cord-263699-gosqpg3k	217	17	the	the	DT
cord-263699-gosqpg3k	217	18	RNA	RNA	NNP
cord-263699-gosqpg3k	217	19	replication	replication	NN
cord-263699-gosqpg3k	217	20	of	of	IN
cord-263699-gosqpg3k	217	21	HEV	HEV	NNP
cord-263699-gosqpg3k	217	22	was	be	VBD
cord-263699-gosqpg3k	217	23	sensitive	sensitive	JJ
cord-263699-gosqpg3k	217	24	to	to	IN
cord-263699-gosqpg3k	217	25	treatments	treatment	NNS
cord-263699-gosqpg3k	217	26	with	with	IN
cord-263699-gosqpg3k	217	27	BFA	BFA	NNP
cord-263699-gosqpg3k	217	28	and	and	CC
cord-263699-gosqpg3k	217	29	GCA	GCA	NNP
cord-263699-gosqpg3k	217	30	,	,	,
cord-263699-gosqpg3k	217	31	and	and	CC
cord-263699-gosqpg3k	217	32	that	that	IN
cord-263699-gosqpg3k	217	33	GBF1	GBF1	NNP
cord-263699-gosqpg3k	217	34	plays	play	VBZ
cord-263699-gosqpg3k	217	35	an	an	DT
cord-263699-gosqpg3k	217	36	essential	essential	JJ
cord-263699-gosqpg3k	217	37	role	role	NN
cord-263699-gosqpg3k	217	38	in	in	IN
cord-263699-gosqpg3k	217	39	this	this	DT
cord-263699-gosqpg3k	217	40	process	process	NN
cord-263699-gosqpg3k	217	41	although	although	IN
cord-263699-gosqpg3k	217	42	,	,	,
cord-263699-gosqpg3k	217	43	unlike	unlike	IN
cord-263699-gosqpg3k	217	44	togaviruses	togaviruse	NNS
cord-263699-gosqpg3k	217	45	,	,	,
cord-263699-gosqpg3k	217	46	the	the	DT
cord-263699-gosqpg3k	217	47	inhibition	inhibition	NN
cord-263699-gosqpg3k	217	48	of	of	IN
cord-263699-gosqpg3k	217	49	GBF1	GBF1	NNP
cord-263699-gosqpg3k	217	50	activity	activity	NN
cord-263699-gosqpg3k	217	51	by	by	IN
cord-263699-gosqpg3k	217	52	BFA	BFA	NNP
cord-263699-gosqpg3k	217	53	does	do	VBZ
cord-263699-gosqpg3k	217	54	not	not	RB
cord-263699-gosqpg3k	217	55	affect	affect	VB
cord-263699-gosqpg3k	217	56	the	the	DT
cord-263699-gosqpg3k	217	57	formation	formation	NN
cord-263699-gosqpg3k	217	58	of	of	IN
cord-263699-gosqpg3k	217	59	the	the	DT
cord-263699-gosqpg3k	217	60	HEV	HEV	NNP
cord-263699-gosqpg3k	217	61	replication	replication	NN
cord-263699-gosqpg3k	217	62	complexes	complex	NNS
cord-263699-gosqpg3k	217	63	.	.	.
cord-263699-gosqpg3k	218	1	The	the	DT
cord-263699-gosqpg3k	218	2	members	member	NNS
cord-263699-gosqpg3k	218	3	of	of	IN
cord-263699-gosqpg3k	218	4	this	this	DT
cord-263699-gosqpg3k	218	5	genus	genus	NN
cord-263699-gosqpg3k	218	6	are	be	VBP
cord-263699-gosqpg3k	218	7	enveloped	envelop	VBN
cord-263699-gosqpg3k	218	8	viruses	virus	NNS
cord-263699-gosqpg3k	218	9	that	that	WDT
cord-263699-gosqpg3k	218	10	contain	contain	VBP
cord-263699-gosqpg3k	218	11	a	a	DT
cord-263699-gosqpg3k	218	12	large	large	JJ
cord-263699-gosqpg3k	218	13	positive	positive	JJ
cord-263699-gosqpg3k	218	14	-	-	HYPH
cord-263699-gosqpg3k	218	15	sense	sense	NN
cord-263699-gosqpg3k	218	16	,	,	,
cord-263699-gosqpg3k	218	17	single	single	RB
cord-263699-gosqpg3k	218	18	-	-	HYPH
cord-263699-gosqpg3k	218	19	stranded	strand	VBN
cord-263699-gosqpg3k	218	20	RNA	RNA	NNP
cord-263699-gosqpg3k	218	21	genome	genome	NN
cord-263699-gosqpg3k	218	22	with	with	IN
cord-263699-gosqpg3k	218	23	several	several	JJ
cord-263699-gosqpg3k	218	24	ORFs	orf	NNS
cord-263699-gosqpg3k	218	25	that	that	WDT
cord-263699-gosqpg3k	218	26	direct	direct	VBP
cord-263699-gosqpg3k	218	27	the	the	DT
cord-263699-gosqpg3k	218	28	synthesis	synthesis	NN
cord-263699-gosqpg3k	218	29	of	of	IN
cord-263699-gosqpg3k	218	30	16	16	CD
cord-263699-gosqpg3k	218	31	nonstructural	nonstructural	JJ
cord-263699-gosqpg3k	218	32	proteins	protein	NNS
cord-263699-gosqpg3k	218	33	(	(	-LRB-
cord-263699-gosqpg3k	218	34	nsp1	nsp1	NNS
cord-263699-gosqpg3k	218	35	to	to	IN
cord-263699-gosqpg3k	218	36	nsp16	nsp16	NNS
cord-263699-gosqpg3k	218	37	)	)	-RRB-
cord-263699-gosqpg3k	218	38	,	,	,
cord-263699-gosqpg3k	218	39	four	four	CD
cord-263699-gosqpg3k	218	40	structural	structural	JJ
cord-263699-gosqpg3k	218	41	proteins	protein	NNS
cord-263699-gosqpg3k	218	42	(	(	-LRB-
cord-263699-gosqpg3k	218	43	S	S	NNP
cord-263699-gosqpg3k	218	44	,	,	,
cord-263699-gosqpg3k	218	45	M	M	NNP
cord-263699-gosqpg3k	218	46	,	,	,
cord-263699-gosqpg3k	218	47	E	E	NNP
cord-263699-gosqpg3k	218	48	,	,	,
cord-263699-gosqpg3k	218	49	and	and	CC
cord-263699-gosqpg3k	218	50	N	N	NNP
cord-263699-gosqpg3k	218	51	)	)	-RRB-
cord-263699-gosqpg3k	218	52	and	and	CC
cord-263699-gosqpg3k	218	53	,	,	,
cord-263699-gosqpg3k	218	54	in	in	IN
cord-263699-gosqpg3k	218	55	some	some	DT
cord-263699-gosqpg3k	218	56	viruses	virus	NNS
cord-263699-gosqpg3k	218	57	,	,	,
cord-263699-gosqpg3k	218	58	a	a	DT
cord-263699-gosqpg3k	218	59	group	group	NN
cord-263699-gosqpg3k	218	60	of	of	IN
cord-263699-gosqpg3k	218	61	up	up	IN
cord-263699-gosqpg3k	218	62	to	to	TO
cord-263699-gosqpg3k	218	63	eight	eight	CD
cord-263699-gosqpg3k	218	64	accessory	accessory	NN
cord-263699-gosqpg3k	218	65	proteins	protein	NNS
cord-263699-gosqpg3k	218	66	that	that	WDT
cord-263699-gosqpg3k	218	67	are	be	VBP
cord-263699-gosqpg3k	218	68	key	key	JJ
cord-263699-gosqpg3k	218	69	for	for	IN
cord-263699-gosqpg3k	218	70	the	the	DT
cord-263699-gosqpg3k	218	71	efficient	efficient	JJ
cord-263699-gosqpg3k	218	72	replication	replication	NN
cord-263699-gosqpg3k	218	73	of	of	IN
cord-263699-gosqpg3k	218	74	the	the	DT
cord-263699-gosqpg3k	218	75	virus	virus	NN
cord-263699-gosqpg3k	218	76	in	in	IN
cord-263699-gosqpg3k	218	77	natural	natural	JJ
cord-263699-gosqpg3k	218	78	conditions	condition	NNS
cord-263699-gosqpg3k	218	79	[	[	-LRB-
cord-263699-gosqpg3k	218	80	121	121	CD
cord-263699-gosqpg3k	218	81	]	]	-RRB-
cord-263699-gosqpg3k	218	82	.	.	.
cord-263699-gosqpg3k	219	1	Once	once	RB
cord-263699-gosqpg3k	219	2	released	release	VBN
cord-263699-gosqpg3k	219	3	in	in	IN
cord-263699-gosqpg3k	219	4	the	the	DT
cord-263699-gosqpg3k	219	5	cytoplasm	cytoplasm	NN
cord-263699-gosqpg3k	219	6	,	,	,
cord-263699-gosqpg3k	219	7	the	the	DT
cord-263699-gosqpg3k	219	8	viral	viral	JJ
cord-263699-gosqpg3k	219	9	RNA	RNA	NNP
cord-263699-gosqpg3k	219	10	directs	direct	VBZ
cord-263699-gosqpg3k	219	11	the	the	DT
cord-263699-gosqpg3k	219	12	synthesis	synthesis	NN
cord-263699-gosqpg3k	219	13	of	of	IN
cord-263699-gosqpg3k	219	14	the	the	DT
cord-263699-gosqpg3k	219	15	nonstructural	nonstructural	JJ
cord-263699-gosqpg3k	219	16	proteins	protein	NNS
cord-263699-gosqpg3k	219	17	that	that	WDT
cord-263699-gosqpg3k	219	18	form	form	VBP
cord-263699-gosqpg3k	219	19	the	the	DT
cord-263699-gosqpg3k	219	20	RdRp	RdRp	NNP
cord-263699-gosqpg3k	219	21	complex	complex	NN
cord-263699-gosqpg3k	219	22	,	,	,
cord-263699-gosqpg3k	219	23	which	which	WDT
cord-263699-gosqpg3k	219	24	transcribes	transcribe	VBZ
cord-263699-gosqpg3k	219	25	the	the	DT
cord-263699-gosqpg3k	219	26	full	full	JJ
cord-263699-gosqpg3k	219	27	-	-	HYPH
cord-263699-gosqpg3k	219	28	length	length	NN
cord-263699-gosqpg3k	219	29	,	,	,
cord-263699-gosqpg3k	219	30	negative	negative	JJ
cord-263699-gosqpg3k	219	31	-	-	HYPH
cord-263699-gosqpg3k	219	32	sense	sense	NN
cord-263699-gosqpg3k	219	33	antigenomic	antigenomic	NNP
cord-263699-gosqpg3k	219	34	RNA	RNA	NNP
cord-263699-gosqpg3k	219	35	.	.	.
cord-263699-gosqpg3k	220	1	The	the	DT
cord-263699-gosqpg3k	220	2	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	220	3	antigenome	antigenome	NN
cord-263699-gosqpg3k	220	4	is	be	VBZ
cord-263699-gosqpg3k	220	5	then	then	RB
cord-263699-gosqpg3k	220	6	used	use	VBN
cord-263699-gosqpg3k	220	7	for	for	IN
cord-263699-gosqpg3k	220	8	the	the	DT
cord-263699-gosqpg3k	220	9	production	production	NN
cord-263699-gosqpg3k	220	10	of	of	IN
cord-263699-gosqpg3k	220	11	the	the	DT
cord-263699-gosqpg3k	220	12	full	full	JJ
cord-263699-gosqpg3k	220	13	-	-	HYPH
cord-263699-gosqpg3k	220	14	length	length	NN
cord-263699-gosqpg3k	220	15	genomic	genomic	JJ
cord-263699-gosqpg3k	220	16	RNA	RNA	NNP
cord-263699-gosqpg3k	220	17	copies	copy	NNS
cord-263699-gosqpg3k	220	18	and	and	CC
cord-263699-gosqpg3k	220	19	a	a	DT
cord-263699-gosqpg3k	220	20	set	set	NN
cord-263699-gosqpg3k	220	21	of	of	IN
cord-263699-gosqpg3k	220	22	subgenomic	subgenomic	NNP
cord-263699-gosqpg3k	220	23	mRNAs	mRNAs	NNPS
cord-263699-gosqpg3k	220	24	of	of	IN
cord-263699-gosqpg3k	220	25	different	different	JJ
cord-263699-gosqpg3k	220	26	lengths	length	NNS
cord-263699-gosqpg3k	220	27	that	that	WDT
cord-263699-gosqpg3k	220	28	direct	direct	VBP
cord-263699-gosqpg3k	220	29	the	the	DT
cord-263699-gosqpg3k	220	30	synthesis	synthesis	NN
cord-263699-gosqpg3k	220	31	of	of	IN
cord-263699-gosqpg3k	220	32	the	the	DT
cord-263699-gosqpg3k	220	33	structural	structural	JJ
cord-263699-gosqpg3k	220	34	and	and	CC
cord-263699-gosqpg3k	220	35	accessory	accessory	NN
cord-263699-gosqpg3k	220	36	proteins	protein	NNS
cord-263699-gosqpg3k	220	37	.	.	.
cord-263699-gosqpg3k	221	1	Following	follow	VBG
cord-263699-gosqpg3k	221	2	their	-PRON-	PRP$
cord-263699-gosqpg3k	221	3	synthesis	synthesis	NN
cord-263699-gosqpg3k	221	4	,	,	,
cord-263699-gosqpg3k	221	5	the	the	DT
cord-263699-gosqpg3k	221	6	structural	structural	JJ
cord-263699-gosqpg3k	221	7	proteins	protein	NNS
cord-263699-gosqpg3k	221	8	S	S	NNP
cord-263699-gosqpg3k	221	9	,	,	,
cord-263699-gosqpg3k	221	10	E	E	NNP
cord-263699-gosqpg3k	221	11	,	,	,
cord-263699-gosqpg3k	221	12	and	and	CC
cord-263699-gosqpg3k	221	13	M	M	NNP
cord-263699-gosqpg3k	221	14	are	be	VBP
cord-263699-gosqpg3k	221	15	inserted	insert	VBN
cord-263699-gosqpg3k	221	16	into	into	IN
cord-263699-gosqpg3k	221	17	the	the	DT
cord-263699-gosqpg3k	221	18	ER	ER	NNP
cord-263699-gosqpg3k	221	19	and	and	CC
cord-263699-gosqpg3k	221	20	then	then	RB
cord-263699-gosqpg3k	221	21	transported	transport	VBD
cord-263699-gosqpg3k	221	22	along	along	IN
cord-263699-gosqpg3k	221	23	the	the	DT
cord-263699-gosqpg3k	221	24	secretory	secretory	JJ
cord-263699-gosqpg3k	221	25	pathway	pathway	NN
cord-263699-gosqpg3k	221	26	up	up	IN
cord-263699-gosqpg3k	221	27	to	to	IN
cord-263699-gosqpg3k	221	28	the	the	DT
cord-263699-gosqpg3k	221	29	ERGIC	ERGIC	NNP
cord-263699-gosqpg3k	221	30	,	,	,
cord-263699-gosqpg3k	221	31	where	where	WRB
cord-263699-gosqpg3k	221	32	the	the	DT
cord-263699-gosqpg3k	221	33	nucleocapsid	nucleocapsid	NN
cord-263699-gosqpg3k	221	34	,	,	,
cord-263699-gosqpg3k	221	35	formed	form	VBN
cord-263699-gosqpg3k	221	36	by	by	IN
cord-263699-gosqpg3k	221	37	the	the	DT
cord-263699-gosqpg3k	221	38	new	new	JJ
cord-263699-gosqpg3k	221	39	RNA	RNA	NNP
cord-263699-gosqpg3k	221	40	genome	genome	NN
cord-263699-gosqpg3k	221	41	bound	bind	VBN
cord-263699-gosqpg3k	221	42	to	to	IN
cord-263699-gosqpg3k	221	43	N	n	CD
cord-263699-gosqpg3k	221	44	proteins	protein	NNS
cord-263699-gosqpg3k	221	45	,	,	,
cord-263699-gosqpg3k	221	46	buds	bud	NNS
cord-263699-gosqpg3k	221	47	to	to	TO
cord-263699-gosqpg3k	221	48	form	form	VB
cord-263699-gosqpg3k	221	49	the	the	DT
cord-263699-gosqpg3k	221	50	mature	mature	JJ
cord-263699-gosqpg3k	221	51	virions	virion	NNS
cord-263699-gosqpg3k	221	52	.	.	.
cord-263699-gosqpg3k	222	1	Following	follow	VBG
cord-263699-gosqpg3k	222	2	assembly	assembly	NN
cord-263699-gosqpg3k	222	3	,	,	,
cord-263699-gosqpg3k	222	4	virions	virion	NNS
cord-263699-gosqpg3k	222	5	are	be	VBP
cord-263699-gosqpg3k	222	6	finally	finally	RB
cord-263699-gosqpg3k	222	7	released	release	VBN
cord-263699-gosqpg3k	222	8	to	to	IN
cord-263699-gosqpg3k	222	9	the	the	DT
cord-263699-gosqpg3k	222	10	extracellular	extracellular	JJ
cord-263699-gosqpg3k	222	11	medium	medium	NN
cord-263699-gosqpg3k	222	12	by	by	IN
cord-263699-gosqpg3k	222	13	exocytosis	exocytosis	NN
cord-263699-gosqpg3k	222	14	.	.	.
cord-263699-gosqpg3k	223	1	During	during	IN
cord-263699-gosqpg3k	223	2	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	223	3	infection	infection	NN
cord-263699-gosqpg3k	223	4	,	,	,
cord-263699-gosqpg3k	223	5	all	all	DT
cord-263699-gosqpg3k	223	6	RNA	RNA	NNP
cord-263699-gosqpg3k	223	7	synthesis	synthesis	NN
cord-263699-gosqpg3k	223	8	processes	process	NNS
cord-263699-gosqpg3k	223	9	occur	occur	VBP
cord-263699-gosqpg3k	223	10	in	in	IN
cord-263699-gosqpg3k	223	11	a	a	DT
cord-263699-gosqpg3k	223	12	replication	replication	NN
cord-263699-gosqpg3k	223	13	-	-	HYPH
cord-263699-gosqpg3k	223	14	transcription	transcription	NN
cord-263699-gosqpg3k	223	15	complex	complex	NN
cord-263699-gosqpg3k	223	16	(	(	-LRB-
cord-263699-gosqpg3k	223	17	RTC	RTC	NNP
cord-263699-gosqpg3k	223	18	)	)	-RRB-
cord-263699-gosqpg3k	223	19	,	,	,
cord-263699-gosqpg3k	223	20	composed	compose	VBN
cord-263699-gosqpg3k	223	21	of	of	IN
cord-263699-gosqpg3k	223	22	viral	viral	JJ
cord-263699-gosqpg3k	223	23	and	and	CC
cord-263699-gosqpg3k	223	24	host	host	NN
cord-263699-gosqpg3k	223	25	proteins	protein	NNS
cord-263699-gosqpg3k	223	26	that	that	WDT
cord-263699-gosqpg3k	223	27	are	be	VBP
cord-263699-gosqpg3k	223	28	associated	associate	VBN
cord-263699-gosqpg3k	223	29	to	to	IN
cord-263699-gosqpg3k	223	30	a	a	DT
cord-263699-gosqpg3k	223	31	reticulo	reticulo	JJ
cord-263699-gosqpg3k	223	32	-	-	HYPH
cord-263699-gosqpg3k	223	33	vesicular	vesicular	JJ
cord-263699-gosqpg3k	223	34	network	network	NN
cord-263699-gosqpg3k	223	35	(	(	-LRB-
cord-263699-gosqpg3k	223	36	RVN	RVN	NNP
cord-263699-gosqpg3k	223	37	)	)	-RRB-
cord-263699-gosqpg3k	223	38	made	make	VBN
cord-263699-gosqpg3k	223	39	of	of	IN
cord-263699-gosqpg3k	223	40	modified	modify	VBN
cord-263699-gosqpg3k	223	41	intracellular	intracellular	JJ
cord-263699-gosqpg3k	223	42	membranes	membrane	NNS
cord-263699-gosqpg3k	223	43	and	and	CC
cord-263699-gosqpg3k	223	44	double	double	JJ
cord-263699-gosqpg3k	223	45	-	-	HYPH
cord-263699-gosqpg3k	223	46	membrane	membrane	NN
cord-263699-gosqpg3k	223	47	vesicles	vesicle	NNS
cord-263699-gosqpg3k	223	48	(	(	-LRB-
cord-263699-gosqpg3k	223	49	DMVs	dmv	NNS
cord-263699-gosqpg3k	223	50	)	)	-RRB-
cord-263699-gosqpg3k	223	51	apparently	apparently	RB
cord-263699-gosqpg3k	223	52	derived	derive	VBN
cord-263699-gosqpg3k	223	53	from	from	IN
cord-263699-gosqpg3k	223	54	the	the	DT
cord-263699-gosqpg3k	223	55	ER	ER	NNP
cord-263699-gosqpg3k	223	56	[	[	-LRB-
cord-263699-gosqpg3k	223	57	121	121	CD
cord-263699-gosqpg3k	223	58	,	,	,
cord-263699-gosqpg3k	223	59	122	122	CD
cord-263699-gosqpg3k	223	60	]	]	-RRB-
cord-263699-gosqpg3k	223	61	.	.	.
cord-263699-gosqpg3k	224	1	Recent	recent	JJ
cord-263699-gosqpg3k	224	2	evidence	evidence	NN
cord-263699-gosqpg3k	224	3	has	have	VBZ
cord-263699-gosqpg3k	224	4	indicated	indicate	VBN
cord-263699-gosqpg3k	224	5	that	that	IN
cord-263699-gosqpg3k	224	6	the	the	DT
cord-263699-gosqpg3k	224	7	secretory	secretory	JJ
cord-263699-gosqpg3k	224	8	pathway	pathway	NN
cord-263699-gosqpg3k	224	9	participates	participate	VBZ
cord-263699-gosqpg3k	224	10	in	in	IN
cord-263699-gosqpg3k	224	11	the	the	DT
cord-263699-gosqpg3k	224	12	formation	formation	NN
cord-263699-gosqpg3k	224	13	and	and	CC
cord-263699-gosqpg3k	224	14	function	function	NN
cord-263699-gosqpg3k	224	15	of	of	IN
cord-263699-gosqpg3k	224	16	both	both	CC
cord-263699-gosqpg3k	224	17	RTC	RTC	NNP
cord-263699-gosqpg3k	224	18	and	and	CC
cord-263699-gosqpg3k	224	19	RVN	RVN	NNP
cord-263699-gosqpg3k	224	20	.	.	.
cord-263699-gosqpg3k	225	1	It	-PRON-	PRP
cord-263699-gosqpg3k	225	2	has	have	VBZ
cord-263699-gosqpg3k	225	3	been	be	VBN
cord-263699-gosqpg3k	225	4	reported	report	VBN
cord-263699-gosqpg3k	225	5	that	that	IN
cord-263699-gosqpg3k	225	6	the	the	DT
cord-263699-gosqpg3k	225	7	inhibition	inhibition	NN
cord-263699-gosqpg3k	225	8	of	of	IN
cord-263699-gosqpg3k	225	9	the	the	DT
cord-263699-gosqpg3k	225	10	secretory	secretory	JJ
cord-263699-gosqpg3k	225	11	pathway	pathway	NN
cord-263699-gosqpg3k	225	12	by	by	IN
cord-263699-gosqpg3k	225	13	BFA	BFA	NNP
cord-263699-gosqpg3k	225	14	or	or	CC
cord-263699-gosqpg3k	225	15	GCA	GCA	NNP
cord-263699-gosqpg3k	225	16	strongly	strongly	RB
cord-263699-gosqpg3k	225	17	reduces	reduce	VBZ
cord-263699-gosqpg3k	225	18	the	the	DT
cord-263699-gosqpg3k	225	19	RNA	RNA	NNP
cord-263699-gosqpg3k	225	20	replication	replication	NN
cord-263699-gosqpg3k	225	21	of	of	IN
cord-263699-gosqpg3k	225	22	different	different	JJ
cord-263699-gosqpg3k	225	23	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	225	24	strains	strain	NNS
cord-263699-gosqpg3k	225	25	such	such	JJ
cord-263699-gosqpg3k	225	26	as	as	IN
cord-263699-gosqpg3k	225	27	the	the	DT
cord-263699-gosqpg3k	225	28	human	human	JJ
cord-263699-gosqpg3k	225	29	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	225	30	229E	229e	CD
cord-263699-gosqpg3k	225	31	(	(	-LRB-
cord-263699-gosqpg3k	225	32	HCoV-229E	HCoV-229E	NNP
cord-263699-gosqpg3k	225	33	,	,	,
cord-263699-gosqpg3k	225	34	alphacoronavirus	alphacoronavirus	NNP
cord-263699-gosqpg3k	225	35	)	)	-RRB-
cord-263699-gosqpg3k	225	36	,	,	,
cord-263699-gosqpg3k	225	37	the	the	DT
cord-263699-gosqpg3k	225	38	mouse	mouse	NN
cord-263699-gosqpg3k	225	39	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	225	40	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	225	41	(	(	-LRB-
cord-263699-gosqpg3k	225	42	MHV	MHV	NNP
cord-263699-gosqpg3k	225	43	,	,	,
cord-263699-gosqpg3k	225	44	betacoronavirus	betacoronavirus	NNP
cord-263699-gosqpg3k	225	45	)	)	-RRB-
cord-263699-gosqpg3k	225	46	,	,	,
cord-263699-gosqpg3k	225	47	and	and	CC
cord-263699-gosqpg3k	225	48	the	the	DT
cord-263699-gosqpg3k	225	49	severe	severe	JJ
cord-263699-gosqpg3k	225	50	acute	acute	JJ
cord-263699-gosqpg3k	225	51	respiratory	respiratory	JJ
cord-263699-gosqpg3k	225	52	syndrome	syndrome	NN
cord-263699-gosqpg3k	225	53	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	225	54	(	(	-LRB-
cord-263699-gosqpg3k	225	55	SARS	SARS	NNP
cord-263699-gosqpg3k	225	56	-	-	HYPH
cord-263699-gosqpg3k	225	57	CoV	CoV	NNP
cord-263699-gosqpg3k	225	58	,	,	,
cord-263699-gosqpg3k	225	59	betacoronavirus	betacoronavirus	NNP
cord-263699-gosqpg3k	225	60	)	)	-RRB-
cord-263699-gosqpg3k	225	61	[	[	-LRB-
cord-263699-gosqpg3k	225	62	51	51	CD
cord-263699-gosqpg3k	225	63	,	,	,
cord-263699-gosqpg3k	225	64	69	69	CD
cord-263699-gosqpg3k	225	65	,	,	,
cord-263699-gosqpg3k	225	66	70	70	CD
cord-263699-gosqpg3k	225	67	]	]	-RRB-
cord-263699-gosqpg3k	225	68	.	.	.
cord-263699-gosqpg3k	226	1	These	these	DT
cord-263699-gosqpg3k	226	2	effects	effect	NNS
cord-263699-gosqpg3k	226	3	were	be	VBD
cord-263699-gosqpg3k	226	4	shown	show	VBN
cord-263699-gosqpg3k	226	5	to	to	TO
cord-263699-gosqpg3k	226	6	be	be	VB
cord-263699-gosqpg3k	226	7	related	relate	VBN
cord-263699-gosqpg3k	226	8	with	with	IN
cord-263699-gosqpg3k	226	9	the	the	DT
cord-263699-gosqpg3k	226	10	specific	specific	JJ
cord-263699-gosqpg3k	226	11	inhibition	inhibition	NN
cord-263699-gosqpg3k	226	12	of	of	IN
cord-263699-gosqpg3k	226	13	the	the	DT
cord-263699-gosqpg3k	226	14	activity	activity	NN
cord-263699-gosqpg3k	226	15	of	of	IN
cord-263699-gosqpg3k	226	16	GBF1	GBF1	NNP
cord-263699-gosqpg3k	226	17	[	[	-LRB-
cord-263699-gosqpg3k	226	18	69	69	CD
cord-263699-gosqpg3k	226	19	,	,	,
cord-263699-gosqpg3k	226	20	71	71	CD
cord-263699-gosqpg3k	226	21	]	]	-RRB-
cord-263699-gosqpg3k	226	22	.	.	.
cord-263699-gosqpg3k	227	1	The	the	DT
cord-263699-gosqpg3k	227	2	precise	precise	JJ
cord-263699-gosqpg3k	227	3	role	role	NN
cord-263699-gosqpg3k	227	4	of	of	IN
cord-263699-gosqpg3k	227	5	GBF1	GBF1	NNP
cord-263699-gosqpg3k	227	6	in	in	IN
cord-263699-gosqpg3k	227	7	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	227	8	RNA	RNA	NNP
cord-263699-gosqpg3k	227	9	replication	replication	NN
cord-263699-gosqpg3k	227	10	is	be	VBZ
cord-263699-gosqpg3k	227	11	not	not	RB
cord-263699-gosqpg3k	227	12	clear	clear	JJ
cord-263699-gosqpg3k	227	13	;	;	:
cord-263699-gosqpg3k	227	14	however	however	RB
cord-263699-gosqpg3k	227	15	,	,	,
cord-263699-gosqpg3k	227	16	given	give	VBN
cord-263699-gosqpg3k	227	17	that	that	IN
cord-263699-gosqpg3k	227	18	the	the	DT
cord-263699-gosqpg3k	227	19	inhibition	inhibition	NN
cord-263699-gosqpg3k	227	20	of	of	IN
cord-263699-gosqpg3k	227	21	this	this	DT
cord-263699-gosqpg3k	227	22	factor	factor	NN
cord-263699-gosqpg3k	227	23	by	by	IN
cord-263699-gosqpg3k	227	24	BFA	BFA	NNP
cord-263699-gosqpg3k	227	25	does	do	VBZ
cord-263699-gosqpg3k	227	26	not	not	RB
cord-263699-gosqpg3k	227	27	alter	alter	VB
cord-263699-gosqpg3k	227	28	the	the	DT
cord-263699-gosqpg3k	227	29	RNA	RNA	NNP
cord-263699-gosqpg3k	227	30	-	-	HYPH
cord-263699-gosqpg3k	227	31	synthesizing	synthesize	VBG
cord-263699-gosqpg3k	227	32	activity	activity	NN
cord-263699-gosqpg3k	227	33	of	of	IN
cord-263699-gosqpg3k	227	34	RTCs	rtc	NNS
cord-263699-gosqpg3k	227	35	,	,	,
cord-263699-gosqpg3k	227	36	but	but	CC
cord-263699-gosqpg3k	227	37	rather	rather	RB
cord-263699-gosqpg3k	227	38	decreases	decrease	VBZ
cord-263699-gosqpg3k	227	39	the	the	DT
cord-263699-gosqpg3k	227	40	number	number	NN
cord-263699-gosqpg3k	227	41	of	of	IN
cord-263699-gosqpg3k	227	42	these	these	DT
cord-263699-gosqpg3k	227	43	organelles	organelle	NNS
cord-263699-gosqpg3k	227	44	,	,	,
cord-263699-gosqpg3k	227	45	as	as	RB
cord-263699-gosqpg3k	227	46	well	well	RB
cord-263699-gosqpg3k	227	47	as	as	IN
cord-263699-gosqpg3k	227	48	the	the	DT
cord-263699-gosqpg3k	227	49	number	number	NN
cord-263699-gosqpg3k	227	50	of	of	IN
cord-263699-gosqpg3k	227	51	DMVs	dmv	NNS
cord-263699-gosqpg3k	227	52	in	in	IN
cord-263699-gosqpg3k	227	53	MHV	MHV	NNP
cord-263699-gosqpg3k	227	54	-	-	:
cord-263699-gosqpg3k	227	55	and	and	CC
cord-263699-gosqpg3k	227	56	SARS	SARS	NNP
cord-263699-gosqpg3k	227	57	-	-	HYPH
cord-263699-gosqpg3k	227	58	CoV	CoV	NNP
cord-263699-gosqpg3k	227	59	-	-	HYPH
cord-263699-gosqpg3k	227	60	infected	infect	VBN
cord-263699-gosqpg3k	227	61	cells	cell	NNS
cord-263699-gosqpg3k	227	62	,	,	,
cord-263699-gosqpg3k	227	63	it	-PRON-	PRP
cord-263699-gosqpg3k	227	64	has	have	VBZ
cord-263699-gosqpg3k	227	65	been	be	VBN
cord-263699-gosqpg3k	227	66	proposed	propose	VBN
cord-263699-gosqpg3k	227	67	that	that	IN
cord-263699-gosqpg3k	227	68	the	the	DT
cord-263699-gosqpg3k	227	69	GBF1	GBF1	NNP
cord-263699-gosqpg3k	227	70	activity	activity	NN
cord-263699-gosqpg3k	227	71	might	may	MD
cord-263699-gosqpg3k	227	72	be	be	VB
cord-263699-gosqpg3k	227	73	required	require	VBN
cord-263699-gosqpg3k	227	74	for	for	IN
cord-263699-gosqpg3k	227	75	the	the	DT
cord-263699-gosqpg3k	227	76	formation	formation	NN
cord-263699-gosqpg3k	227	77	of	of	IN
cord-263699-gosqpg3k	227	78	the	the	DT
cord-263699-gosqpg3k	227	79	virus	virus	NN
cord-263699-gosqpg3k	227	80	-	-	HYPH
cord-263699-gosqpg3k	227	81	induced	induce	VBN
cord-263699-gosqpg3k	227	82	RVN	RVN	NNP
cord-263699-gosqpg3k	227	83	[	[	-LRB-
cord-263699-gosqpg3k	227	84	69	69	CD
cord-263699-gosqpg3k	227	85	,	,	,
cord-263699-gosqpg3k	227	86	70	70	CD
cord-263699-gosqpg3k	227	87	]	]	-RRB-
cord-263699-gosqpg3k	227	88	.	.	.
cord-263699-gosqpg3k	228	1	Altogether	altogether	RB
cord-263699-gosqpg3k	228	2	,	,	,
cord-263699-gosqpg3k	228	3	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	228	4	infection	infection	NN
cord-263699-gosqpg3k	228	5	seems	seem	VBZ
cord-263699-gosqpg3k	228	6	to	to	TO
cord-263699-gosqpg3k	228	7	redirect	redirect	VB
cord-263699-gosqpg3k	228	8	the	the	DT
cord-263699-gosqpg3k	228	9	vesicle	vesicle	NN
cord-263699-gosqpg3k	228	10	transport	transport	NN
cord-263699-gosqpg3k	228	11	mediated	mediate	VBN
cord-263699-gosqpg3k	228	12	by	by	IN
cord-263699-gosqpg3k	228	13	GBF1	GBF1	NNP
cord-263699-gosqpg3k	228	14	toward	toward	IN
cord-263699-gosqpg3k	228	15	the	the	DT
cord-263699-gosqpg3k	228	16	RTCs	rtc	NNS
cord-263699-gosqpg3k	228	17	to	to	TO
cord-263699-gosqpg3k	228	18	maintain	maintain	VB
cord-263699-gosqpg3k	228	19	the	the	DT
cord-263699-gosqpg3k	228	20	correct	correct	JJ
cord-263699-gosqpg3k	228	21	morphology	morphology	NN
cord-263699-gosqpg3k	228	22	of	of	IN
cord-263699-gosqpg3k	228	23	these	these	DT
cord-263699-gosqpg3k	228	24	viral	viral	JJ
cord-263699-gosqpg3k	228	25	organelles	organelle	NNS
cord-263699-gosqpg3k	228	26	.	.	.
cord-263699-gosqpg3k	229	1	In	in	IN
cord-263699-gosqpg3k	229	2	support	support	NN
cord-263699-gosqpg3k	229	3	of	of	IN
cord-263699-gosqpg3k	229	4	this	this	DT
cord-263699-gosqpg3k	229	5	proposal	proposal	NN
cord-263699-gosqpg3k	229	6	,	,	,
cord-263699-gosqpg3k	229	7	the	the	DT
cord-263699-gosqpg3k	229	8	silencing	silencing	NN
cord-263699-gosqpg3k	229	9	of	of	IN
cord-263699-gosqpg3k	229	10	Arf	Arf	NNP
cord-263699-gosqpg3k	229	11	proteins	protein	NNS
cord-263699-gosqpg3k	229	12	or	or	CC
cord-263699-gosqpg3k	229	13	subunits	subunit	NNS
cord-263699-gosqpg3k	229	14	of	of	IN
cord-263699-gosqpg3k	229	15	the	the	DT
cord-263699-gosqpg3k	229	16	COPI	COPI	NNP
cord-263699-gosqpg3k	229	17	complex	complex	JJ
cord-263699-gosqpg3k	229	18	has	have	VBZ
cord-263699-gosqpg3k	229	19	shown	show	VBN
cord-263699-gosqpg3k	229	20	to	to	TO
cord-263699-gosqpg3k	229	21	induce	induce	VB
cord-263699-gosqpg3k	229	22	a	a	DT
cord-263699-gosqpg3k	229	23	similar	similar	JJ
cord-263699-gosqpg3k	229	24	inhibitory	inhibitory	JJ
cord-263699-gosqpg3k	229	25	effect	effect	NN
cord-263699-gosqpg3k	229	26	on	on	IN
cord-263699-gosqpg3k	229	27	MHV	MHV	NNP
cord-263699-gosqpg3k	229	28	and	and	CC
cord-263699-gosqpg3k	229	29	HCoV-229E	HCoV-229E	NNP
cord-263699-gosqpg3k	229	30	replication	replication	NN
cord-263699-gosqpg3k	229	31	,	,	,
cord-263699-gosqpg3k	229	32	similar	similar	JJ
cord-263699-gosqpg3k	229	33	to	to	IN
cord-263699-gosqpg3k	229	34	that	that	DT
cord-263699-gosqpg3k	229	35	observed	observe	VBN
cord-263699-gosqpg3k	229	36	with	with	IN
cord-263699-gosqpg3k	229	37	the	the	DT
cord-263699-gosqpg3k	229	38	GBF1	GBF1	NNP
cord-263699-gosqpg3k	229	39	depletion	depletion	NN
cord-263699-gosqpg3k	229	40	[	[	-LRB-
cord-263699-gosqpg3k	229	41	51	51	CD
cord-263699-gosqpg3k	229	42	,	,	,
cord-263699-gosqpg3k	229	43	71	71	CD
cord-263699-gosqpg3k	229	44	]	]	-RRB-
cord-263699-gosqpg3k	229	45	.	.	.
cord-263699-gosqpg3k	230	1	On	on	IN
cord-263699-gosqpg3k	230	2	the	the	DT
cord-263699-gosqpg3k	230	3	other	other	JJ
cord-263699-gosqpg3k	230	4	hand	hand	NN
cord-263699-gosqpg3k	230	5	,	,	,
cord-263699-gosqpg3k	230	6	the	the	DT
cord-263699-gosqpg3k	230	7	finding	finding	NN
cord-263699-gosqpg3k	230	8	that	that	DT
cord-263699-gosqpg3k	230	9	overexpression	overexpression	NN
cord-263699-gosqpg3k	230	10	of	of	IN
cord-263699-gosqpg3k	230	11	the	the	DT
cord-263699-gosqpg3k	230	12	dominant	dominant	JJ
cord-263699-gosqpg3k	230	13	-	-	HYPH
cord-263699-gosqpg3k	230	14	negative	negative	JJ
cord-263699-gosqpg3k	230	15	mutant	mutant	NN
cord-263699-gosqpg3k	230	16	Arf1-T31N	Arf1-T31N	NNP
cord-263699-gosqpg3k	230	17	strongly	strongly	RB
cord-263699-gosqpg3k	230	18	inhibits	inhibit	VBZ
cord-263699-gosqpg3k	230	19	MHV	mhv	NN
cord-263699-gosqpg3k	230	20	replication	replication	NN
cord-263699-gosqpg3k	230	21	[	[	-LRB-
cord-263699-gosqpg3k	230	22	69	69	CD
cord-263699-gosqpg3k	230	23	]	]	-RRB-
cord-263699-gosqpg3k	230	24	,	,	,
cord-263699-gosqpg3k	230	25	together	together	RB
cord-263699-gosqpg3k	230	26	with	with	IN
cord-263699-gosqpg3k	230	27	the	the	DT
cord-263699-gosqpg3k	230	28	fact	fact	NN
cord-263699-gosqpg3k	230	29	that	that	IN
cord-263699-gosqpg3k	230	30	this	this	DT
cord-263699-gosqpg3k	230	31	Arf	Arf	NNP
cord-263699-gosqpg3k	230	32	mutant	mutant	NN
cord-263699-gosqpg3k	230	33	has	have	VBZ
cord-263699-gosqpg3k	230	34	been	be	VBN
cord-263699-gosqpg3k	230	35	shown	show	VBN
cord-263699-gosqpg3k	230	36	to	to	TO
cord-263699-gosqpg3k	230	37	inhibit	inhibit	VB
cord-263699-gosqpg3k	230	38	the	the	DT
cord-263699-gosqpg3k	230	39	ERGIC	ergic	NN
cord-263699-gosqpg3k	230	40	to	to	IN
cord-263699-gosqpg3k	230	41	ER	ER	NNP
cord-263699-gosqpg3k	230	42	transport	transport	VB
cord-263699-gosqpg3k	230	43	[	[	-LRB-
cord-263699-gosqpg3k	230	44	123	123	CD
cord-263699-gosqpg3k	230	45	]	]	-RRB-
cord-263699-gosqpg3k	230	46	,	,	,
cord-263699-gosqpg3k	230	47	lead	lead	VBP
cord-263699-gosqpg3k	230	48	to	to	TO
cord-263699-gosqpg3k	230	49	suggest	suggest	VB
cord-263699-gosqpg3k	230	50	that	that	IN
cord-263699-gosqpg3k	230	51	GBF1	GBF1	NNP
cord-263699-gosqpg3k	230	52	might	may	MD
cord-263699-gosqpg3k	230	53	regulate	regulate	VB
cord-263699-gosqpg3k	230	54	the	the	DT
cord-263699-gosqpg3k	230	55	maturation	maturation	NN
cord-263699-gosqpg3k	230	56	of	of	IN
cord-263699-gosqpg3k	230	57	RVN	RVN	NNP
cord-263699-gosqpg3k	230	58	through	through	IN
cord-263699-gosqpg3k	230	59	the	the	DT
cord-263699-gosqpg3k	230	60	retrograde	retrograde	JJ
cord-263699-gosqpg3k	230	61	vesicular	vesicular	JJ
cord-263699-gosqpg3k	230	62	transport	transport	NN
cord-263699-gosqpg3k	230	63	of	of	IN
cord-263699-gosqpg3k	230	64	membrane	membrane	NN
cord-263699-gosqpg3k	230	65	lipids	lipid	NNS
cord-263699-gosqpg3k	230	66	from	from	IN
cord-263699-gosqpg3k	230	67	the	the	DT
cord-263699-gosqpg3k	230	68	ERGIC	ERGIC	NNP
cord-263699-gosqpg3k	230	69	to	to	IN
cord-263699-gosqpg3k	230	70	the	the	DT
cord-263699-gosqpg3k	230	71	ER	ER	NNP
cord-263699-gosqpg3k	230	72	[	[	-LRB-
cord-263699-gosqpg3k	230	73	69	69	CD
cord-263699-gosqpg3k	230	74	]	]	-RRB-
cord-263699-gosqpg3k	230	75	.	.	.
cord-263699-gosqpg3k	231	1	The	the	DT
cord-263699-gosqpg3k	231	2	Vesiculovirus	Vesiculovirus	NNP
cord-263699-gosqpg3k	231	3	genus	genus	NN
cord-263699-gosqpg3k	231	4	comprises	comprise	VBZ
cord-263699-gosqpg3k	231	5	a	a	DT
cord-263699-gosqpg3k	231	6	distinct	distinct	JJ
cord-263699-gosqpg3k	231	7	monophyletic	monophyletic	JJ
cord-263699-gosqpg3k	231	8	group	group	NN
cord-263699-gosqpg3k	231	9	of	of	IN
cord-263699-gosqpg3k	231	10	enveloped	envelop	VBN
cord-263699-gosqpg3k	231	11	bullet	bullet	NN
cord-263699-gosqpg3k	231	12	-	-	HYPH
cord-263699-gosqpg3k	231	13	shaped	shape	VBN
cord-263699-gosqpg3k	231	14	viruses	virus	NNS
cord-263699-gosqpg3k	231	15	that	that	WDT
cord-263699-gosqpg3k	231	16	contain	contain	VBP
cord-263699-gosqpg3k	231	17	a	a	DT
cord-263699-gosqpg3k	231	18	negative	negative	JJ
cord-263699-gosqpg3k	231	19	-	-	HYPH
cord-263699-gosqpg3k	231	20	sense	sense	NN
cord-263699-gosqpg3k	231	21	,	,	,
cord-263699-gosqpg3k	231	22	single	single	RB
cord-263699-gosqpg3k	231	23	-	-	HYPH
cord-263699-gosqpg3k	231	24	stranded	strand	VBN
cord-263699-gosqpg3k	231	25	RNA	RNA	NNP
cord-263699-gosqpg3k	231	26	genome	genome	NN
cord-263699-gosqpg3k	231	27	that	that	WDT
cord-263699-gosqpg3k	231	28	codes	code	VBZ
cord-263699-gosqpg3k	231	29	for	for	IN
cord-263699-gosqpg3k	231	30	five	five	CD
cord-263699-gosqpg3k	231	31	structural	structural	JJ
cord-263699-gosqpg3k	231	32	proteins	protein	NNS
cord-263699-gosqpg3k	231	33	:	:	:
cord-263699-gosqpg3k	231	34	the	the	DT
cord-263699-gosqpg3k	231	35	nucleocapsid	nucleocapsid	NNP
cord-263699-gosqpg3k	231	36	protein	protein	NNP
cord-263699-gosqpg3k	231	37	(	(	-LRB-
cord-263699-gosqpg3k	231	38	N	N	NNP
cord-263699-gosqpg3k	231	39	)	)	-RRB-
cord-263699-gosqpg3k	231	40	,	,	,
cord-263699-gosqpg3k	231	41	the	the	DT
cord-263699-gosqpg3k	231	42	phosphoprotein	phosphoprotein	NN
cord-263699-gosqpg3k	231	43	(	(	-LRB-
cord-263699-gosqpg3k	231	44	P	p	NN
cord-263699-gosqpg3k	231	45	)	)	-RRB-
cord-263699-gosqpg3k	231	46	,	,	,
cord-263699-gosqpg3k	231	47	the	the	DT
cord-263699-gosqpg3k	231	48	matrix	matrix	NN
cord-263699-gosqpg3k	231	49	protein	protein	NN
cord-263699-gosqpg3k	231	50	(	(	-LRB-
cord-263699-gosqpg3k	231	51	M	M	NNP
cord-263699-gosqpg3k	231	52	)	)	-RRB-
cord-263699-gosqpg3k	231	53	,	,	,
cord-263699-gosqpg3k	231	54	the	the	DT
cord-263699-gosqpg3k	231	55	glycoprotein	glycoprotein	NN
cord-263699-gosqpg3k	231	56	(	(	-LRB-
cord-263699-gosqpg3k	231	57	G	G	NNP
cord-263699-gosqpg3k	231	58	)	)	-RRB-
cord-263699-gosqpg3k	231	59	,	,	,
cord-263699-gosqpg3k	231	60	and	and	CC
cord-263699-gosqpg3k	231	61	the	the	DT
cord-263699-gosqpg3k	231	62	RdRp	RdRp	NNP
cord-263699-gosqpg3k	231	63	(	(	-LRB-
cord-263699-gosqpg3k	231	64	L	L	NNP
cord-263699-gosqpg3k	231	65	)	)	-RRB-
cord-263699-gosqpg3k	231	66	.	.	.
cord-263699-gosqpg3k	232	1	After	after	IN
cord-263699-gosqpg3k	232	2	virus	virus	NN
cord-263699-gosqpg3k	232	3	entry	entry	NN
cord-263699-gosqpg3k	232	4	into	into	IN
cord-263699-gosqpg3k	232	5	the	the	DT
cord-263699-gosqpg3k	232	6	cell	cell	NN
cord-263699-gosqpg3k	232	7	,	,	,
cord-263699-gosqpg3k	232	8	the	the	DT
cord-263699-gosqpg3k	232	9	viral	viral	JJ
cord-263699-gosqpg3k	232	10	nucleocapsid	nucleocapsid	NN
cord-263699-gosqpg3k	232	11	is	be	VBZ
cord-263699-gosqpg3k	232	12	released	release	VBN
cord-263699-gosqpg3k	232	13	into	into	IN
cord-263699-gosqpg3k	232	14	the	the	DT
cord-263699-gosqpg3k	232	15	cytoplasm	cytoplasm	NN
cord-263699-gosqpg3k	232	16	.	.	.
cord-263699-gosqpg3k	233	1	Once	once	RB
cord-263699-gosqpg3k	233	2	free	free	JJ
cord-263699-gosqpg3k	233	3	,	,	,
cord-263699-gosqpg3k	233	4	the	the	DT
cord-263699-gosqpg3k	233	5	virion	virion	NN
cord-263699-gosqpg3k	233	6	polymerase	polymerase	NN
cord-263699-gosqpg3k	233	7	complex	complex	NN
cord-263699-gosqpg3k	233	8	,	,	,
cord-263699-gosqpg3k	233	9	composed	compose	VBN
cord-263699-gosqpg3k	233	10	by	by	IN
cord-263699-gosqpg3k	233	11	the	the	DT
cord-263699-gosqpg3k	233	12	N	N	NNP
cord-263699-gosqpg3k	233	13	,	,	,
cord-263699-gosqpg3k	233	14	P	P	NNP
cord-263699-gosqpg3k	233	15	,	,	,
cord-263699-gosqpg3k	233	16	and	and	CC
cord-263699-gosqpg3k	233	17	L	l	NN
cord-263699-gosqpg3k	233	18	proteins	protein	NNS
cord-263699-gosqpg3k	233	19	drives	drive	VBZ
cord-263699-gosqpg3k	233	20	the	the	DT
cord-263699-gosqpg3k	233	21	transcription	transcription	NN
cord-263699-gosqpg3k	233	22	of	of	IN
cord-263699-gosqpg3k	233	23	the	the	DT
cord-263699-gosqpg3k	233	24	viral	viral	NN
cord-263699-gosqpg3k	233	25	mRNAs	mrna	NNS
cord-263699-gosqpg3k	233	26	,	,	,
cord-263699-gosqpg3k	233	27	which	which	WDT
cord-263699-gosqpg3k	233	28	then	then	RB
cord-263699-gosqpg3k	233	29	direct	direct	VBP
cord-263699-gosqpg3k	233	30	the	the	DT
cord-263699-gosqpg3k	233	31	synthesis	synthesis	NN
cord-263699-gosqpg3k	233	32	of	of	IN
cord-263699-gosqpg3k	233	33	the	the	DT
cord-263699-gosqpg3k	233	34	different	different	JJ
cord-263699-gosqpg3k	233	35	viral	viral	JJ
cord-263699-gosqpg3k	233	36	proteins	protein	NNS
cord-263699-gosqpg3k	233	37	.	.	.
cord-263699-gosqpg3k	234	1	Once	once	IN
cord-263699-gosqpg3k	234	2	sufficient	sufficient	JJ
cord-263699-gosqpg3k	234	3	quantities	quantity	NNS
cord-263699-gosqpg3k	234	4	of	of	IN
cord-263699-gosqpg3k	234	5	the	the	DT
cord-263699-gosqpg3k	234	6	N	N	NNP
cord-263699-gosqpg3k	234	7	and	and	CC
cord-263699-gosqpg3k	234	8	P	P	NNP
cord-263699-gosqpg3k	234	9	protein	protein	NN
cord-263699-gosqpg3k	234	10	have	have	VBP
cord-263699-gosqpg3k	234	11	been	be	VBN
cord-263699-gosqpg3k	234	12	produced	produce	VBN
cord-263699-gosqpg3k	234	13	,	,	,
cord-263699-gosqpg3k	234	14	the	the	DT
cord-263699-gosqpg3k	234	15	virion	virion	NN
cord-263699-gosqpg3k	234	16	polymerase	polymerase	NN
cord-263699-gosqpg3k	234	17	complex	complex	NN
cord-263699-gosqpg3k	234	18	starts	start	VBZ
cord-263699-gosqpg3k	234	19	the	the	DT
cord-263699-gosqpg3k	234	20	synthesis	synthesis	NN
cord-263699-gosqpg3k	234	21	of	of	IN
cord-263699-gosqpg3k	234	22	a	a	DT
cord-263699-gosqpg3k	234	23	full	full	JJ
cord-263699-gosqpg3k	234	24	-	-	HYPH
cord-263699-gosqpg3k	234	25	length	length	NN
cord-263699-gosqpg3k	234	26	complementary	complementary	JJ
cord-263699-gosqpg3k	234	27	antigenome	antigenome	NNP
cord-263699-gosqpg3k	234	28	RNA	RNA	NNP
cord-263699-gosqpg3k	234	29	of	of	IN
cord-263699-gosqpg3k	234	30	positive	positive	JJ
cord-263699-gosqpg3k	234	31	sense	sense	NN
cord-263699-gosqpg3k	234	32	.	.	.
cord-263699-gosqpg3k	235	1	The	the	DT
cord-263699-gosqpg3k	235	2	antigenome	antigenome	NN
cord-263699-gosqpg3k	235	3	then	then	RB
cord-263699-gosqpg3k	235	4	serves	serve	VBZ
cord-263699-gosqpg3k	235	5	as	as	IN
cord-263699-gosqpg3k	235	6	a	a	DT
cord-263699-gosqpg3k	235	7	template	template	NN
cord-263699-gosqpg3k	235	8	to	to	TO
cord-263699-gosqpg3k	235	9	synthetize	synthetize	VB
cord-263699-gosqpg3k	235	10	new	new	JJ
cord-263699-gosqpg3k	235	11	viral	viral	JJ
cord-263699-gosqpg3k	235	12	negative	negative	JJ
cord-263699-gosqpg3k	235	13	-	-	HYPH
cord-263699-gosqpg3k	235	14	sense	sense	NN
cord-263699-gosqpg3k	235	15	genome	genome	NN
cord-263699-gosqpg3k	235	16	molecules	molecule	NNS
cord-263699-gosqpg3k	235	17	,	,	,
cord-263699-gosqpg3k	235	18	which	which	WDT
cord-263699-gosqpg3k	235	19	can	can	MD
cord-263699-gosqpg3k	235	20	be	be	VB
cord-263699-gosqpg3k	235	21	used	use	VBN
cord-263699-gosqpg3k	235	22	for	for	IN
cord-263699-gosqpg3k	235	23	a	a	DT
cord-263699-gosqpg3k	235	24	second	second	JJ
cord-263699-gosqpg3k	235	25	round	round	NN
cord-263699-gosqpg3k	235	26	of	of	IN
cord-263699-gosqpg3k	235	27	transcription	transcription	NN
cord-263699-gosqpg3k	235	28	or	or	CC
cord-263699-gosqpg3k	235	29	can	can	MD
cord-263699-gosqpg3k	235	30	be	be	VB
cord-263699-gosqpg3k	235	31	assembled	assemble	VBN
cord-263699-gosqpg3k	235	32	into	into	IN
cord-263699-gosqpg3k	235	33	new	new	JJ
cord-263699-gosqpg3k	235	34	viral	viral	JJ
cord-263699-gosqpg3k	235	35	particles	particle	NNS
cord-263699-gosqpg3k	235	36	.	.	.
cord-263699-gosqpg3k	236	1	The	the	DT
cord-263699-gosqpg3k	236	2	union	union	NN
cord-263699-gosqpg3k	236	3	of	of	IN
cord-263699-gosqpg3k	236	4	the	the	DT
cord-263699-gosqpg3k	236	5	N	N	NNP
cord-263699-gosqpg3k	236	6	protein	protein	NN
cord-263699-gosqpg3k	236	7	to	to	IN
cord-263699-gosqpg3k	236	8	the	the	DT
cord-263699-gosqpg3k	236	9	newly	newly	RB
cord-263699-gosqpg3k	236	10	genomic	genomic	JJ
cord-263699-gosqpg3k	236	11	RNA	RNA	NNP
cord-263699-gosqpg3k	236	12	compromises	compromise	VBZ
cord-263699-gosqpg3k	236	13	these	these	DT
cord-263699-gosqpg3k	236	14	molecules	molecule	NNS
cord-263699-gosqpg3k	236	15	to	to	IN
cord-263699-gosqpg3k	236	16	the	the	DT
cord-263699-gosqpg3k	236	17	formation	formation	NN
cord-263699-gosqpg3k	236	18	of	of	IN
cord-263699-gosqpg3k	236	19	helical	helical	JJ
cord-263699-gosqpg3k	236	20	nucleocapsids	nucleocapsid	NNS
cord-263699-gosqpg3k	236	21	that	that	WDT
cord-263699-gosqpg3k	236	22	interact	interact	VBP
cord-263699-gosqpg3k	236	23	with	with	IN
cord-263699-gosqpg3k	236	24	the	the	DT
cord-263699-gosqpg3k	236	25	M	M	NNP
cord-263699-gosqpg3k	236	26	protein	protein	NN
cord-263699-gosqpg3k	236	27	and	and	CC
cord-263699-gosqpg3k	236	28	are	be	VBP
cord-263699-gosqpg3k	236	29	transported	transport	VBN
cord-263699-gosqpg3k	236	30	to	to	IN
cord-263699-gosqpg3k	236	31	cell	cell	NN
cord-263699-gosqpg3k	236	32	membrane	membrane	NN
cord-263699-gosqpg3k	236	33	sites	site	NNS
cord-263699-gosqpg3k	236	34	enriched	enrich	VBN
cord-263699-gosqpg3k	236	35	by	by	IN
cord-263699-gosqpg3k	236	36	the	the	DT
cord-263699-gosqpg3k	236	37	spike	spike	NN
cord-263699-gosqpg3k	236	38	G	g	NN
cord-263699-gosqpg3k	236	39	glycoprotein	glycoprotein	NN
cord-263699-gosqpg3k	236	40	.	.	.
cord-263699-gosqpg3k	237	1	Budding	bud	VBG
cord-263699-gosqpg3k	237	2	of	of	IN
cord-263699-gosqpg3k	237	3	the	the	DT
cord-263699-gosqpg3k	237	4	nucleocapsid	nucleocapsid	NN
cord-263699-gosqpg3k	237	5	through	through	IN
cord-263699-gosqpg3k	237	6	these	these	DT
cord-263699-gosqpg3k	237	7	sites	site	NNS
cord-263699-gosqpg3k	237	8	leads	lead	VBZ
cord-263699-gosqpg3k	237	9	to	to	IN
cord-263699-gosqpg3k	237	10	the	the	DT
cord-263699-gosqpg3k	237	11	formation	formation	NN
cord-263699-gosqpg3k	237	12	of	of	IN
cord-263699-gosqpg3k	237	13	the	the	DT
cord-263699-gosqpg3k	237	14	final	final	JJ
cord-263699-gosqpg3k	237	15	enveloped	envelop	VBN
cord-263699-gosqpg3k	237	16	virus	virus	NN
cord-263699-gosqpg3k	237	17	[	[	-LRB-
cord-263699-gosqpg3k	237	18	124	124	CD
cord-263699-gosqpg3k	237	19	]	]	-RRB-
cord-263699-gosqpg3k	237	20	.	.	.
cord-263699-gosqpg3k	238	1	Given	give	VBN
cord-263699-gosqpg3k	238	2	that	that	IN
cord-263699-gosqpg3k	238	3	the	the	DT
cord-263699-gosqpg3k	238	4	transport	transport	NN
cord-263699-gosqpg3k	238	5	of	of	IN
cord-263699-gosqpg3k	238	6	the	the	DT
cord-263699-gosqpg3k	238	7	G	g	NN
cord-263699-gosqpg3k	238	8	protein	protein	NN
cord-263699-gosqpg3k	238	9	to	to	IN
cord-263699-gosqpg3k	238	10	the	the	DT
cord-263699-gosqpg3k	238	11	cell	cell	NN
cord-263699-gosqpg3k	238	12	membrane	membrane	NN
cord-263699-gosqpg3k	238	13	depends	depend	VBZ
cord-263699-gosqpg3k	238	14	on	on	IN
cord-263699-gosqpg3k	238	15	a	a	DT
cord-263699-gosqpg3k	238	16	functional	functional	JJ
cord-263699-gosqpg3k	238	17	secretory	secretory	JJ
cord-263699-gosqpg3k	238	18	pathway	pathway	NN
cord-263699-gosqpg3k	238	19	,	,	,
cord-263699-gosqpg3k	238	20	the	the	DT
cord-263699-gosqpg3k	238	21	vesicular	vesicular	JJ
cord-263699-gosqpg3k	238	22	transport	transport	NN
cord-263699-gosqpg3k	238	23	was	be	VBD
cord-263699-gosqpg3k	238	24	thought	think	VBN
cord-263699-gosqpg3k	238	25	to	to	TO
cord-263699-gosqpg3k	238	26	only	only	RB
cord-263699-gosqpg3k	238	27	play	play	VB
cord-263699-gosqpg3k	238	28	a	a	DT
cord-263699-gosqpg3k	238	29	role	role	NN
cord-263699-gosqpg3k	238	30	in	in	IN
cord-263699-gosqpg3k	238	31	the	the	DT
cord-263699-gosqpg3k	238	32	final	final	JJ
cord-263699-gosqpg3k	238	33	steps	step	NNS
cord-263699-gosqpg3k	238	34	of	of	IN
cord-263699-gosqpg3k	238	35	vesiculovirus	vesiculovirus	NNP
cord-263699-gosqpg3k	238	36	replication	replication	NN
cord-263699-gosqpg3k	238	37	.	.	.
cord-263699-gosqpg3k	239	1	However	however	RB
cord-263699-gosqpg3k	239	2	,	,	,
cord-263699-gosqpg3k	239	3	studies	study	NNS
cord-263699-gosqpg3k	239	4	with	with	IN
cord-263699-gosqpg3k	239	5	the	the	DT
cord-263699-gosqpg3k	239	6	vesicular	vesicular	JJ
cord-263699-gosqpg3k	239	7	stomatitis	stomatitis	NN
cord-263699-gosqpg3k	239	8	virus	virus	NN
cord-263699-gosqpg3k	239	9	(	(	-LRB-
cord-263699-gosqpg3k	239	10	VSV	VSV	NNP
cord-263699-gosqpg3k	239	11	)	)	-RRB-
cord-263699-gosqpg3k	239	12	,	,	,
cord-263699-gosqpg3k	239	13	the	the	DT
cord-263699-gosqpg3k	239	14	prototypic	prototypic	NNP
cord-263699-gosqpg3k	239	15	member	member	NN
cord-263699-gosqpg3k	239	16	of	of	IN
cord-263699-gosqpg3k	239	17	this	this	DT
cord-263699-gosqpg3k	239	18	genus	genus	NN
cord-263699-gosqpg3k	239	19	,	,	,
cord-263699-gosqpg3k	239	20	revealed	reveal	VBD
cord-263699-gosqpg3k	239	21	that	that	IN
cord-263699-gosqpg3k	239	22	this	this	DT
cord-263699-gosqpg3k	239	23	transport	transport	NN
cord-263699-gosqpg3k	239	24	was	be	VBD
cord-263699-gosqpg3k	239	25	also	also	RB
cord-263699-gosqpg3k	239	26	important	important	JJ
cord-263699-gosqpg3k	239	27	for	for	IN
cord-263699-gosqpg3k	239	28	the	the	DT
cord-263699-gosqpg3k	239	29	synthesis	synthesis	NN
cord-263699-gosqpg3k	239	30	of	of	IN
cord-263699-gosqpg3k	239	31	the	the	DT
cord-263699-gosqpg3k	239	32	viral	viral	JJ
cord-263699-gosqpg3k	239	33	RNA	RNA	NNP
cord-263699-gosqpg3k	239	34	.	.	.
cord-263699-gosqpg3k	240	1	It	-PRON-	PRP
cord-263699-gosqpg3k	240	2	was	be	VBD
cord-263699-gosqpg3k	240	3	observed	observe	VBN
cord-263699-gosqpg3k	240	4	that	that	IN
cord-263699-gosqpg3k	240	5	BFA	BFA	NNP
cord-263699-gosqpg3k	240	6	or	or	CC
cord-263699-gosqpg3k	240	7	GCA	GCA	NNP
cord-263699-gosqpg3k	240	8	treatments	treatment	NNS
cord-263699-gosqpg3k	240	9	induce	induce	VBP
cord-263699-gosqpg3k	240	10	a	a	DT
cord-263699-gosqpg3k	240	11	substantial	substantial	JJ
cord-263699-gosqpg3k	240	12	reduction	reduction	NN
cord-263699-gosqpg3k	240	13	in	in	IN
cord-263699-gosqpg3k	240	14	the	the	DT
cord-263699-gosqpg3k	240	15	levels	level	NNS
cord-263699-gosqpg3k	240	16	of	of	IN
cord-263699-gosqpg3k	240	17	viral	viral	JJ
cord-263699-gosqpg3k	240	18	mRNA	mrna	NN
cord-263699-gosqpg3k	240	19	,	,	,
cord-263699-gosqpg3k	240	20	and	and	CC
cord-263699-gosqpg3k	240	21	the	the	DT
cord-263699-gosqpg3k	240	22	antigenome	antigenome	NNP
cord-263699-gosqpg3k	240	23	RNA	RNA	NNP
cord-263699-gosqpg3k	240	24	of	of	IN
cord-263699-gosqpg3k	240	25	VSV	VSV	NNP
cord-263699-gosqpg3k	240	26	[	[	-LRB-
cord-263699-gosqpg3k	240	27	72	72	CD
cord-263699-gosqpg3k	240	28	,	,	,
cord-263699-gosqpg3k	240	29	125	125	CD
cord-263699-gosqpg3k	240	30	,	,	,
cord-263699-gosqpg3k	240	31	126	126	CD
cord-263699-gosqpg3k	240	32	]	]	-RRB-
cord-263699-gosqpg3k	240	33	.	.	.
cord-263699-gosqpg3k	241	1	The	the	DT
cord-263699-gosqpg3k	241	2	action	action	NN
cord-263699-gosqpg3k	241	3	of	of	IN
cord-263699-gosqpg3k	241	4	these	these	DT
cord-263699-gosqpg3k	241	5	inhibitors	inhibitor	NNS
cord-263699-gosqpg3k	241	6	was	be	VBD
cord-263699-gosqpg3k	241	7	shown	show	VBN
cord-263699-gosqpg3k	241	8	to	to	TO
cord-263699-gosqpg3k	241	9	be	be	VB
cord-263699-gosqpg3k	241	10	related	relate	VBN
cord-263699-gosqpg3k	241	11	to	to	IN
cord-263699-gosqpg3k	241	12	the	the	DT
cord-263699-gosqpg3k	241	13	GBF1	GBF1	NNP
cord-263699-gosqpg3k	241	14	protein	protein	NN
cord-263699-gosqpg3k	241	15	[	[	-LRB-
cord-263699-gosqpg3k	241	16	72	72	CD
cord-263699-gosqpg3k	241	17	,	,	,
cord-263699-gosqpg3k	241	18	125	125	CD
cord-263699-gosqpg3k	241	19	]	]	-RRB-
cord-263699-gosqpg3k	241	20	.	.	.
cord-263699-gosqpg3k	242	1	Although	although	IN
cord-263699-gosqpg3k	242	2	the	the	DT
cord-263699-gosqpg3k	242	3	exact	exact	JJ
cord-263699-gosqpg3k	242	4	role	role	NN
cord-263699-gosqpg3k	242	5	of	of	IN
cord-263699-gosqpg3k	242	6	GBF1	GBF1	NNP
cord-263699-gosqpg3k	242	7	in	in	IN
cord-263699-gosqpg3k	242	8	RNA	RNA	NNP
cord-263699-gosqpg3k	242	9	synthesis	synthesis	NN
cord-263699-gosqpg3k	242	10	is	be	VBZ
cord-263699-gosqpg3k	242	11	unknown	unknown	JJ
cord-263699-gosqpg3k	242	12	,	,	,
cord-263699-gosqpg3k	242	13	taking	take	VBG
cord-263699-gosqpg3k	242	14	into	into	IN
cord-263699-gosqpg3k	242	15	account	account	NN
cord-263699-gosqpg3k	242	16	that	that	IN
cord-263699-gosqpg3k	242	17	the	the	DT
cord-263699-gosqpg3k	242	18	depletion	depletion	NN
cord-263699-gosqpg3k	242	19	of	of	IN
cord-263699-gosqpg3k	242	20	Arf1	Arf1	NNP
cord-263699-gosqpg3k	242	21	or	or	CC
cord-263699-gosqpg3k	242	22	the	the	DT
cord-263699-gosqpg3k	242	23	overexpression	overexpression	NN
cord-263699-gosqpg3k	242	24	of	of	IN
cord-263699-gosqpg3k	242	25	the	the	DT
cord-263699-gosqpg3k	242	26	dominant	dominant	JJ
cord-263699-gosqpg3k	242	27	-	-	HYPH
cord-263699-gosqpg3k	242	28	negative	negative	JJ
cord-263699-gosqpg3k	242	29	mutant	mutant	NN
cord-263699-gosqpg3k	243	1	Arf1-T31N	Arf1-T31N	NNP
cord-263699-gosqpg3k	243	2	decrease	decrease	VBP
cord-263699-gosqpg3k	243	3	the	the	DT
cord-263699-gosqpg3k	243	4	abundance	abundance	NN
cord-263699-gosqpg3k	243	5	of	of	IN
cord-263699-gosqpg3k	243	6	viral	viral	JJ
cord-263699-gosqpg3k	243	7	RNA	RNA	NNP
cord-263699-gosqpg3k	243	8	products	product	NNS
cord-263699-gosqpg3k	243	9	and	and	CC
cord-263699-gosqpg3k	243	10	reduce	reduce	VB
cord-263699-gosqpg3k	243	11	the	the	DT
cord-263699-gosqpg3k	243	12	VSV	VSV	NNP
cord-263699-gosqpg3k	243	13	gene	gene	NN
cord-263699-gosqpg3k	243	14	expression	expression	NN
cord-263699-gosqpg3k	243	15	[	[	-LRB-
cord-263699-gosqpg3k	243	16	72	72	CD
cord-263699-gosqpg3k	243	17	]	]	-RRB-
cord-263699-gosqpg3k	244	1	,	,	,
cord-263699-gosqpg3k	244	2	it	-PRON-	PRP
cord-263699-gosqpg3k	244	3	seems	seem	VBZ
cord-263699-gosqpg3k	244	4	that	that	IN
cord-263699-gosqpg3k	244	5	the	the	DT
cord-263699-gosqpg3k	244	6	role	role	NN
cord-263699-gosqpg3k	244	7	of	of	IN
cord-263699-gosqpg3k	244	8	GBF1	GBF1	NNP
cord-263699-gosqpg3k	244	9	in	in	IN
cord-263699-gosqpg3k	244	10	the	the	DT
cord-263699-gosqpg3k	244	11	process	process	NN
cord-263699-gosqpg3k	244	12	might	may	MD
cord-263699-gosqpg3k	244	13	be	be	VB
cord-263699-gosqpg3k	244	14	related	relate	VBN
cord-263699-gosqpg3k	244	15	to	to	IN
cord-263699-gosqpg3k	244	16	vesicle	vesicle	NN
cord-263699-gosqpg3k	244	17	transport	transport	NN
cord-263699-gosqpg3k	244	18	.	.	.
cord-263699-gosqpg3k	245	1	On	on	IN
cord-263699-gosqpg3k	245	2	the	the	DT
cord-263699-gosqpg3k	245	3	other	other	JJ
cord-263699-gosqpg3k	245	4	hand	hand	NN
cord-263699-gosqpg3k	245	5	,	,	,
cord-263699-gosqpg3k	245	6	a	a	DT
cord-263699-gosqpg3k	245	7	structure	structure	NN
cord-263699-gosqpg3k	245	8	-	-	HYPH
cord-263699-gosqpg3k	245	9	based	base	VBN
cord-263699-gosqpg3k	245	10	computational	computational	JJ
cord-263699-gosqpg3k	245	11	analysis	analysis	NN
cord-263699-gosqpg3k	245	12	of	of	IN
cord-263699-gosqpg3k	245	13	possible	possible	JJ
cord-263699-gosqpg3k	245	14	protein	protein	NN
cord-263699-gosqpg3k	245	15	-	-	HYPH
cord-263699-gosqpg3k	245	16	protein	protein	NN
cord-263699-gosqpg3k	245	17	interactions	interaction	NNS
cord-263699-gosqpg3k	245	18	between	between	IN
cord-263699-gosqpg3k	245	19	human	human	JJ
cord-263699-gosqpg3k	245	20	proteins	protein	NNS
cord-263699-gosqpg3k	245	21	and	and	CC
cord-263699-gosqpg3k	245	22	the	the	DT
cord-263699-gosqpg3k	245	23	proteins	protein	NNS
cord-263699-gosqpg3k	245	24	of	of	IN
cord-263699-gosqpg3k	245	25	Chandipura	Chandipura	NNP
cord-263699-gosqpg3k	245	26	virus	virus	NN
cord-263699-gosqpg3k	245	27	(	(	-LRB-
cord-263699-gosqpg3k	245	28	CHPV	CHPV	NNP
cord-263699-gosqpg3k	245	29	)	)	-RRB-
cord-263699-gosqpg3k	245	30	,	,	,
cord-263699-gosqpg3k	245	31	another	another	DT
cord-263699-gosqpg3k	245	32	member	member	NN
cord-263699-gosqpg3k	245	33	of	of	IN
cord-263699-gosqpg3k	245	34	the	the	DT
cord-263699-gosqpg3k	245	35	Vesiculovirus	Vesiculovirus	NNP
cord-263699-gosqpg3k	245	36	genus	genus	NN
cord-263699-gosqpg3k	245	37	,	,	,
cord-263699-gosqpg3k	245	38	which	which	WDT
cord-263699-gosqpg3k	245	39	has	have	VBZ
cord-263699-gosqpg3k	245	40	emerged	emerge	VBN
cord-263699-gosqpg3k	245	41	as	as	IN
cord-263699-gosqpg3k	245	42	a	a	DT
cord-263699-gosqpg3k	245	43	pediatric	pediatric	JJ
cord-263699-gosqpg3k	245	44	encephalitic	encephalitic	JJ
cord-263699-gosqpg3k	245	45	virus	virus	NN
cord-263699-gosqpg3k	245	46	in	in	IN
cord-263699-gosqpg3k	245	47	India	India	NNP
cord-263699-gosqpg3k	245	48	[	[	-LRB-
cord-263699-gosqpg3k	245	49	127	127	CD
cord-263699-gosqpg3k	245	50	,	,	,
cord-263699-gosqpg3k	245	51	128	128	CD
cord-263699-gosqpg3k	245	52	]	]	-RRB-
cord-263699-gosqpg3k	245	53	,	,	,
cord-263699-gosqpg3k	245	54	revealed	reveal	VBD
cord-263699-gosqpg3k	245	55	that	that	IN
cord-263699-gosqpg3k	245	56	GBF1	GBF1	NNP
cord-263699-gosqpg3k	245	57	and	and	CC
cord-263699-gosqpg3k	245	58	Arf1	Arf1	NNP
cord-263699-gosqpg3k	245	59	exhibit	exhibit	VB
cord-263699-gosqpg3k	245	60	a	a	DT
cord-263699-gosqpg3k	245	61	high	high	JJ
cord-263699-gosqpg3k	245	62	potential	potential	NN
cord-263699-gosqpg3k	245	63	for	for	IN
cord-263699-gosqpg3k	245	64	interaction	interaction	NN
cord-263699-gosqpg3k	245	65	with	with	IN
cord-263699-gosqpg3k	245	66	the	the	DT
cord-263699-gosqpg3k	245	67	G	G	NNP
cord-263699-gosqpg3k	245	68	and	and	CC
cord-263699-gosqpg3k	245	69	L	l	NN
cord-263699-gosqpg3k	245	70	proteins	protein	NNS
cord-263699-gosqpg3k	245	71	of	of	IN
cord-263699-gosqpg3k	245	72	this	this	DT
cord-263699-gosqpg3k	245	73	virus	virus	NN
cord-263699-gosqpg3k	245	74	[	[	-LRB-
cord-263699-gosqpg3k	245	75	129	129	CD
cord-263699-gosqpg3k	245	76	]	]	-RRB-
cord-263699-gosqpg3k	245	77	.	.	.
cord-263699-gosqpg3k	246	1	Although	although	IN
cord-263699-gosqpg3k	246	2	the	the	DT
cord-263699-gosqpg3k	246	3	association	association	NN
cord-263699-gosqpg3k	246	4	of	of	IN
cord-263699-gosqpg3k	246	5	GBF1	GBF1	NNP
cord-263699-gosqpg3k	246	6	and	and	CC
cord-263699-gosqpg3k	246	7	Arf1	Arf1	NNP
cord-263699-gosqpg3k	246	8	with	with	IN
cord-263699-gosqpg3k	246	9	the	the	DT
cord-263699-gosqpg3k	246	10	G	g	NN
cord-263699-gosqpg3k	246	11	protein	protein	NN
cord-263699-gosqpg3k	246	12	was	be	VBD
cord-263699-gosqpg3k	246	13	rather	rather	RB
cord-263699-gosqpg3k	246	14	expected	expect	VBN
cord-263699-gosqpg3k	246	15	,	,	,
cord-263699-gosqpg3k	246	16	given	give	VBN
cord-263699-gosqpg3k	246	17	the	the	DT
cord-263699-gosqpg3k	246	18	association	association	NN
cord-263699-gosqpg3k	246	19	of	of	IN
cord-263699-gosqpg3k	246	20	the	the	DT
cord-263699-gosqpg3k	246	21	G	G	NNP
cord-263699-gosqpg3k	246	22	protein	protein	NN
cord-263699-gosqpg3k	246	23	with	with	IN
cord-263699-gosqpg3k	246	24	the	the	DT
cord-263699-gosqpg3k	246	25	secretory	secretory	JJ
cord-263699-gosqpg3k	246	26	pathway	pathway	NN
cord-263699-gosqpg3k	246	27	,	,	,
cord-263699-gosqpg3k	246	28	the	the	DT
cord-263699-gosqpg3k	246	29	potential	potential	JJ
cord-263699-gosqpg3k	246	30	interaction	interaction	NN
cord-263699-gosqpg3k	246	31	of	of	IN
cord-263699-gosqpg3k	246	32	GBF1	GBF1	NNP
cord-263699-gosqpg3k	246	33	and	and	CC
cord-263699-gosqpg3k	246	34	Arf1	Arf1	NNP
cord-263699-gosqpg3k	246	35	with	with	IN
cord-263699-gosqpg3k	246	36	the	the	DT
cord-263699-gosqpg3k	246	37	polymerase	polymerase	NN
cord-263699-gosqpg3k	246	38	L	L	NNP
cord-263699-gosqpg3k	246	39	of	of	IN
cord-263699-gosqpg3k	246	40	CHPV	CHPV	NNP
cord-263699-gosqpg3k	246	41	is	be	VBZ
cord-263699-gosqpg3k	246	42	a	a	DT
cord-263699-gosqpg3k	246	43	surprising	surprising	JJ
cord-263699-gosqpg3k	246	44	finding	finding	NN
cord-263699-gosqpg3k	246	45	that	that	WDT
cord-263699-gosqpg3k	246	46	might	may	MD
cord-263699-gosqpg3k	246	47	indicate	indicate	VB
cord-263699-gosqpg3k	246	48	that	that	IN
cord-263699-gosqpg3k	246	49	GBF1	GBF1	NNP
cord-263699-gosqpg3k	246	50	could	could	MD
cord-263699-gosqpg3k	246	51	directly	directly	RB
cord-263699-gosqpg3k	246	52	regulate	regulate	VB
cord-263699-gosqpg3k	246	53	the	the	DT
cord-263699-gosqpg3k	246	54	activity	activity	NN
cord-263699-gosqpg3k	246	55	of	of	IN
cord-263699-gosqpg3k	246	56	the	the	DT
cord-263699-gosqpg3k	246	57	L	L	NNP
cord-263699-gosqpg3k	246	58	protein	protein	NN
cord-263699-gosqpg3k	246	59	during	during	IN
cord-263699-gosqpg3k	246	60	viral	viral	JJ
cord-263699-gosqpg3k	246	61	RNA	RNA	NNP
cord-263699-gosqpg3k	246	62	replication	replication	NN
cord-263699-gosqpg3k	246	63	;	;	:
cord-263699-gosqpg3k	246	64	the	the	DT
cord-263699-gosqpg3k	246	65	interaction	interaction	NN
cord-263699-gosqpg3k	246	66	between	between	IN
cord-263699-gosqpg3k	246	67	GBF1	GBF1	NNP
cord-263699-gosqpg3k	246	68	and	and	CC
cord-263699-gosqpg3k	246	69	the	the	DT
cord-263699-gosqpg3k	246	70	L	L	NNP
cord-263699-gosqpg3k	246	71	protein	protein	NN
cord-263699-gosqpg3k	246	72	was	be	VBD
cord-263699-gosqpg3k	246	73	not	not	RB
cord-263699-gosqpg3k	246	74	corroborated	corroborate	VBN
cord-263699-gosqpg3k	246	75	by	by	IN
cord-263699-gosqpg3k	246	76	biochemical	biochemical	JJ
cord-263699-gosqpg3k	246	77	assays	assay	NNS
cord-263699-gosqpg3k	246	78	.	.	.
cord-263699-gosqpg3k	247	1	On	on	IN
cord-263699-gosqpg3k	247	2	the	the	DT
cord-263699-gosqpg3k	247	3	other	other	JJ
cord-263699-gosqpg3k	247	4	hand	hand	NN
cord-263699-gosqpg3k	247	5	,	,	,
cord-263699-gosqpg3k	247	6	considering	consider	VBG
cord-263699-gosqpg3k	247	7	that	that	IN
cord-263699-gosqpg3k	247	8	the	the	DT
cord-263699-gosqpg3k	247	9	microtubule	microtubule	NN
cord-263699-gosqpg3k	247	10	-	-	HYPH
cord-263699-gosqpg3k	247	11	dependent	dependent	JJ
cord-263699-gosqpg3k	247	12	transport	transport	NN
cord-263699-gosqpg3k	247	13	of	of	IN
cord-263699-gosqpg3k	247	14	viral	viral	NN
cord-263699-gosqpg3k	247	15	mRNAs	mRNAs	NNPS
cord-263699-gosqpg3k	247	16	from	from	IN
cord-263699-gosqpg3k	247	17	the	the	DT
cord-263699-gosqpg3k	247	18	VSV	VSV	NNP
cord-263699-gosqpg3k	247	19	inclusions	inclusion	NNS
cord-263699-gosqpg3k	247	20	to	to	IN
cord-263699-gosqpg3k	247	21	the	the	DT
cord-263699-gosqpg3k	247	22	cytoplasm	cytoplasm	NN
cord-263699-gosqpg3k	247	23	has	have	VBZ
cord-263699-gosqpg3k	247	24	been	be	VBN
cord-263699-gosqpg3k	247	25	proved	prove	VBN
cord-263699-gosqpg3k	247	26	to	to	TO
cord-263699-gosqpg3k	247	27	be	be	VB
cord-263699-gosqpg3k	247	28	essential	essential	JJ
cord-263699-gosqpg3k	247	29	for	for	IN
cord-263699-gosqpg3k	247	30	their	-PRON-	PRP$
cord-263699-gosqpg3k	247	31	efficient	efficient	JJ
cord-263699-gosqpg3k	247	32	translation	translation	NN
cord-263699-gosqpg3k	247	33	[	[	-LRB-
cord-263699-gosqpg3k	247	34	130	130	CD
cord-263699-gosqpg3k	247	35	]	]	-RRB-
cord-263699-gosqpg3k	247	36	,	,	,
cord-263699-gosqpg3k	247	37	it	-PRON-	PRP
cord-263699-gosqpg3k	247	38	might	may	MD
cord-263699-gosqpg3k	247	39	also	also	RB
cord-263699-gosqpg3k	247	40	be	be	VB
cord-263699-gosqpg3k	247	41	possible	possible	JJ
cord-263699-gosqpg3k	247	42	that	that	IN
cord-263699-gosqpg3k	247	43	GBF1	GBF1	NNP
cord-263699-gosqpg3k	247	44	promotes	promote	VBZ
cord-263699-gosqpg3k	247	45	the	the	DT
cord-263699-gosqpg3k	247	46	protein	protein	NN
cord-263699-gosqpg3k	247	47	expression	expression	NN
cord-263699-gosqpg3k	247	48	of	of	IN
cord-263699-gosqpg3k	247	49	vesiculoviruses	vesiculovirus	NNS
cord-263699-gosqpg3k	247	50	by	by	IN
cord-263699-gosqpg3k	247	51	facilitating	facilitate	VBG
cord-263699-gosqpg3k	247	52	the	the	DT
cord-263699-gosqpg3k	247	53	transport	transport	NN
cord-263699-gosqpg3k	247	54	of	of	IN
cord-263699-gosqpg3k	247	55	viral	viral	NN
cord-263699-gosqpg3k	247	56	mRNAs	mrna	NNS
cord-263699-gosqpg3k	247	57	out	out	IN
cord-263699-gosqpg3k	247	58	of	of	IN
cord-263699-gosqpg3k	247	59	the	the	DT
cord-263699-gosqpg3k	247	60	inclusions	inclusion	NNS
cord-263699-gosqpg3k	247	61	through	through	IN
cord-263699-gosqpg3k	247	62	the	the	DT
cord-263699-gosqpg3k	247	63	activation	activation	NN
cord-263699-gosqpg3k	247	64	of	of	IN
cord-263699-gosqpg3k	247	65	Arf1	Arf1	NNP
cord-263699-gosqpg3k	247	66	and	and	CC
cord-263699-gosqpg3k	247	67	the	the	DT
cord-263699-gosqpg3k	247	68	subsequent	subsequent	JJ
cord-263699-gosqpg3k	247	69	recruitment	recruitment	NN
cord-263699-gosqpg3k	247	70	of	of	IN
cord-263699-gosqpg3k	247	71	COPI	COPI	NNP
cord-263699-gosqpg3k	247	72	elements	element	NNS
cord-263699-gosqpg3k	247	73	.	.	.
cord-263699-gosqpg3k	248	1	In	in	IN
cord-263699-gosqpg3k	248	2	support	support	NN
cord-263699-gosqpg3k	248	3	of	of	IN
cord-263699-gosqpg3k	248	4	this	this	DT
cord-263699-gosqpg3k	248	5	model	model	NN
cord-263699-gosqpg3k	248	6	,	,	,
cord-263699-gosqpg3k	248	7	it	-PRON-	PRP
cord-263699-gosqpg3k	248	8	has	have	VBZ
cord-263699-gosqpg3k	248	9	been	be	VBN
cord-263699-gosqpg3k	248	10	reported	report	VBN
cord-263699-gosqpg3k	248	11	that	that	IN
cord-263699-gosqpg3k	248	12	VSV	VSV	NNP
cord-263699-gosqpg3k	248	13	infection	infection	NN
cord-263699-gosqpg3k	248	14	can	can	MD
cord-263699-gosqpg3k	248	15	be	be	VB
cord-263699-gosqpg3k	248	16	inhibited	inhibit	VBN
cord-263699-gosqpg3k	248	17	by	by	IN
cord-263699-gosqpg3k	248	18	microinjection	microinjection	NN
cord-263699-gosqpg3k	248	19	of	of	IN
cord-263699-gosqpg3k	248	20	an	an	DT
cord-263699-gosqpg3k	248	21	antibody	antibody	NN
cord-263699-gosqpg3k	248	22	against	against	IN
cord-263699-gosqpg3k	248	23	COP	cop	NN
cord-263699-gosqpg3k	248	24	-	-	HYPH
cord-263699-gosqpg3k	248	25	β	β	NNP
cord-263699-gosqpg3k	248	26	that	that	WDT
cord-263699-gosqpg3k	248	27	blocks	block	VBZ
cord-263699-gosqpg3k	248	28	the	the	DT
cord-263699-gosqpg3k	248	29	transport	transport	NN
cord-263699-gosqpg3k	248	30	between	between	IN
cord-263699-gosqpg3k	248	31	the	the	DT
cord-263699-gosqpg3k	248	32	ER	ER	NNP
cord-263699-gosqpg3k	248	33	and	and	CC
cord-263699-gosqpg3k	248	34	Golgi	Golgi	NNP
cord-263699-gosqpg3k	248	35	[	[	-LRB-
cord-263699-gosqpg3k	248	36	131	131	CD
cord-263699-gosqpg3k	248	37	]	]	-RRB-
cord-263699-gosqpg3k	248	38	.	.	.
cord-263699-gosqpg3k	249	1	Influenza	influenza	NN
cord-263699-gosqpg3k	249	2	viruses	virus	NNS
cord-263699-gosqpg3k	249	3	are	be	VBP
cord-263699-gosqpg3k	249	4	enveloped	envelop	VBN
cord-263699-gosqpg3k	249	5	viruses	virus	NNS
cord-263699-gosqpg3k	249	6	that	that	WDT
cord-263699-gosqpg3k	249	7	contain	contain	VBP
cord-263699-gosqpg3k	249	8	a	a	DT
cord-263699-gosqpg3k	249	9	segmented	segmented	JJ
cord-263699-gosqpg3k	249	10	negative	negative	JJ
cord-263699-gosqpg3k	249	11	-	-	HYPH
cord-263699-gosqpg3k	249	12	sense	sense	NN
cord-263699-gosqpg3k	249	13	,	,	,
cord-263699-gosqpg3k	249	14	single	single	RB
cord-263699-gosqpg3k	249	15	-	-	HYPH
cord-263699-gosqpg3k	249	16	stranded	strand	VBN
cord-263699-gosqpg3k	249	17	RNA	RNA	NNP
cord-263699-gosqpg3k	249	18	genome	genome	NN
cord-263699-gosqpg3k	249	19	that	that	WDT
cord-263699-gosqpg3k	249	20	can	can	MD
cord-263699-gosqpg3k	249	21	be	be	VB
cord-263699-gosqpg3k	249	22	formed	form	VBN
cord-263699-gosqpg3k	249	23	by	by	IN
cord-263699-gosqpg3k	249	24	seven	seven	CD
cord-263699-gosqpg3k	249	25	or	or	CC
cord-263699-gosqpg3k	249	26	eight	eight	CD
cord-263699-gosqpg3k	249	27	RNA	RNA	NNP
cord-263699-gosqpg3k	249	28	segments	segment	NNS
cord-263699-gosqpg3k	249	29	,	,	,
cord-263699-gosqpg3k	249	30	depending	depend	VBG
cord-263699-gosqpg3k	249	31	on	on	IN
cord-263699-gosqpg3k	249	32	the	the	DT
cord-263699-gosqpg3k	249	33	virus	virus	NN
cord-263699-gosqpg3k	249	34	strain	strain	NN
cord-263699-gosqpg3k	249	35	.	.	.
cord-263699-gosqpg3k	250	1	The	the	DT
cord-263699-gosqpg3k	250	2	genome	genome	NN
cord-263699-gosqpg3k	250	3	of	of	IN
cord-263699-gosqpg3k	250	4	these	these	DT
cord-263699-gosqpg3k	250	5	viruses	virus	NNS
cord-263699-gosqpg3k	250	6	codes	code	NNS
cord-263699-gosqpg3k	250	7	for	for	IN
cord-263699-gosqpg3k	250	8	three	three	CD
cord-263699-gosqpg3k	250	9	proteins	protein	NNS
cord-263699-gosqpg3k	250	10	that	that	WDT
cord-263699-gosqpg3k	250	11	form	form	VBP
cord-263699-gosqpg3k	250	12	the	the	DT
cord-263699-gosqpg3k	250	13	viral	viral	JJ
cord-263699-gosqpg3k	250	14	RdRp	RdRp	NNP
cord-263699-gosqpg3k	250	15	(	(	-LRB-
cord-263699-gosqpg3k	250	16	PA	PA	NNP
cord-263699-gosqpg3k	250	17	,	,	,
cord-263699-gosqpg3k	250	18	PB1	PB1	NNP
cord-263699-gosqpg3k	250	19	,	,	,
cord-263699-gosqpg3k	250	20	PB2	PB2	NNP
cord-263699-gosqpg3k	250	21	)	)	-RRB-
cord-263699-gosqpg3k	250	22	,	,	,
cord-263699-gosqpg3k	250	23	a	a	DT
cord-263699-gosqpg3k	250	24	nucleoprotein	nucleoprotein	NNP
cord-263699-gosqpg3k	250	25	(	(	-LRB-
cord-263699-gosqpg3k	250	26	NP	NP	NNP
cord-263699-gosqpg3k	250	27	)	)	-RRB-
cord-263699-gosqpg3k	250	28	that	that	WDT
cord-263699-gosqpg3k	250	29	is	be	VBZ
cord-263699-gosqpg3k	250	30	associated	associate	VBN
cord-263699-gosqpg3k	250	31	with	with	IN
cord-263699-gosqpg3k	250	32	each	each	DT
cord-263699-gosqpg3k	250	33	genome	genome	NN
cord-263699-gosqpg3k	250	34	segment	segment	NN
cord-263699-gosqpg3k	250	35	,	,	,
cord-263699-gosqpg3k	250	36	a	a	DT
cord-263699-gosqpg3k	250	37	hemagglutinin	hemagglutinin	NN
cord-263699-gosqpg3k	250	38	(	(	-LRB-
cord-263699-gosqpg3k	250	39	HA	HA	NNP
cord-263699-gosqpg3k	250	40	)	)	-RRB-
cord-263699-gosqpg3k	250	41	protein	protein	NN
cord-263699-gosqpg3k	250	42	that	that	WDT
cord-263699-gosqpg3k	250	43	facilitates	facilitate	VBZ
cord-263699-gosqpg3k	250	44	virus	virus	NN
cord-263699-gosqpg3k	250	45	attachment	attachment	NN
cord-263699-gosqpg3k	250	46	,	,	,
cord-263699-gosqpg3k	250	47	and	and	CC
cord-263699-gosqpg3k	250	48	the	the	DT
cord-263699-gosqpg3k	250	49	matrix	matrix	NN
cord-263699-gosqpg3k	250	50	protein	protein	NN
cord-263699-gosqpg3k	250	51	1	1	CD
cord-263699-gosqpg3k	250	52	(	(	-LRB-
cord-263699-gosqpg3k	250	53	M1	M1	NNP
cord-263699-gosqpg3k	250	54	)	)	-RRB-
cord-263699-gosqpg3k	250	55	that	that	WDT
cord-263699-gosqpg3k	250	56	acts	act	VBZ
cord-263699-gosqpg3k	250	57	as	as	IN
cord-263699-gosqpg3k	250	58	an	an	DT
cord-263699-gosqpg3k	250	59	adaptor	adaptor	NN
cord-263699-gosqpg3k	250	60	protein	protein	NN
cord-263699-gosqpg3k	250	61	between	between	IN
cord-263699-gosqpg3k	250	62	the	the	DT
cord-263699-gosqpg3k	250	63	viral	viral	JJ
cord-263699-gosqpg3k	250	64	ribonucleoproteins	ribonucleoprotein	NNS
cord-263699-gosqpg3k	250	65	(	(	-LRB-
cord-263699-gosqpg3k	250	66	RNPs	RNPs	NNP
cord-263699-gosqpg3k	250	67	)	)	-RRB-
cord-263699-gosqpg3k	250	68	and	and	CC
cord-263699-gosqpg3k	250	69	the	the	DT
cord-263699-gosqpg3k	250	70	membrane	membrane	NN
cord-263699-gosqpg3k	250	71	envelope	envelope	NN
cord-263699-gosqpg3k	250	72	.	.	.
cord-263699-gosqpg3k	251	1	Moreover	moreover	RB
cord-263699-gosqpg3k	251	2	,	,	,
cord-263699-gosqpg3k	251	3	some	some	DT
cord-263699-gosqpg3k	251	4	members	member	NNS
cord-263699-gosqpg3k	251	5	also	also	RB
cord-263699-gosqpg3k	251	6	code	code	VBP
cord-263699-gosqpg3k	251	7	for	for	IN
cord-263699-gosqpg3k	251	8	a	a	DT
cord-263699-gosqpg3k	251	9	neuraminidase	neuraminidase	NN
cord-263699-gosqpg3k	251	10	(	(	-LRB-
cord-263699-gosqpg3k	251	11	NA	NA	NNP
cord-263699-gosqpg3k	251	12	)	)	-RRB-
cord-263699-gosqpg3k	251	13	that	that	WDT
cord-263699-gosqpg3k	251	14	contains	contain	VBZ
cord-263699-gosqpg3k	251	15	sialidase	sialidase	NN
cord-263699-gosqpg3k	251	16	activity	activity	NN
cord-263699-gosqpg3k	251	17	essential	essential	JJ
cord-263699-gosqpg3k	251	18	for	for	IN
cord-263699-gosqpg3k	251	19	the	the	DT
cord-263699-gosqpg3k	251	20	releasing	releasing	NN
cord-263699-gosqpg3k	251	21	of	of	IN
cord-263699-gosqpg3k	251	22	the	the	DT
cord-263699-gosqpg3k	251	23	mature	mature	JJ
cord-263699-gosqpg3k	251	24	viral	viral	JJ
cord-263699-gosqpg3k	251	25	particles	particle	NNS
cord-263699-gosqpg3k	251	26	,	,	,
cord-263699-gosqpg3k	251	27	and	and	CC
cord-263699-gosqpg3k	251	28	a	a	DT
cord-263699-gosqpg3k	251	29	small	small	JJ
cord-263699-gosqpg3k	251	30	integral	integral	JJ
cord-263699-gosqpg3k	251	31	membrane	membrane	NN
cord-263699-gosqpg3k	251	32	matrix	matrix	NN
cord-263699-gosqpg3k	251	33	protein	protein	NN
cord-263699-gosqpg3k	251	34	2	2	CD
cord-263699-gosqpg3k	251	35	(	(	-LRB-
cord-263699-gosqpg3k	251	36	M2	M2	NNP
cord-263699-gosqpg3k	251	37	)	)	-RRB-
cord-263699-gosqpg3k	251	38	,	,	,
cord-263699-gosqpg3k	251	39	a	a	DT
cord-263699-gosqpg3k	251	40	proton	proton	NN
cord-263699-gosqpg3k	251	41	selective	selective	JJ
cord-263699-gosqpg3k	251	42	ion	ion	NN
cord-263699-gosqpg3k	251	43	channel	channel	NN
cord-263699-gosqpg3k	251	44	.	.	.
cord-263699-gosqpg3k	252	1	In	in	IN
cord-263699-gosqpg3k	252	2	addition	addition	NN
cord-263699-gosqpg3k	252	3	to	to	IN
cord-263699-gosqpg3k	252	4	structural	structural	JJ
cord-263699-gosqpg3k	252	5	proteins	protein	NNS
cord-263699-gosqpg3k	252	6	,	,	,
cord-263699-gosqpg3k	252	7	these	these	DT
cord-263699-gosqpg3k	252	8	viruses	virus	NNS
cord-263699-gosqpg3k	252	9	may	may	MD
cord-263699-gosqpg3k	252	10	also	also	RB
cord-263699-gosqpg3k	252	11	code	code	VB
cord-263699-gosqpg3k	252	12	for	for	IN
cord-263699-gosqpg3k	252	13	two	two	CD
cord-263699-gosqpg3k	252	14	nonstructural	nonstructural	JJ
cord-263699-gosqpg3k	252	15	proteins	protein	NNS
cord-263699-gosqpg3k	252	16	(	(	-LRB-
cord-263699-gosqpg3k	252	17	NS1	ns1	UH
cord-263699-gosqpg3k	252	18	,	,	,
cord-263699-gosqpg3k	252	19	NS2	NS2	NNP
cord-263699-gosqpg3k	252	20	)	)	-RRB-
cord-263699-gosqpg3k	252	21	.	.	.
cord-263699-gosqpg3k	253	1	After	after	IN
cord-263699-gosqpg3k	253	2	cell	cell	NN
cord-263699-gosqpg3k	253	3	entry	entry	NN
cord-263699-gosqpg3k	253	4	,	,	,
cord-263699-gosqpg3k	253	5	the	the	DT
cord-263699-gosqpg3k	253	6	RNPs	rnp	NNS
cord-263699-gosqpg3k	253	7	are	be	VBP
cord-263699-gosqpg3k	253	8	released	release	VBN
cord-263699-gosqpg3k	253	9	into	into	IN
cord-263699-gosqpg3k	253	10	the	the	DT
cord-263699-gosqpg3k	253	11	cytoplasm	cytoplasm	NN
cord-263699-gosqpg3k	253	12	;	;	:
cord-263699-gosqpg3k	253	13	once	once	RB
cord-263699-gosqpg3k	253	14	free	free	JJ
cord-263699-gosqpg3k	253	15	,	,	,
cord-263699-gosqpg3k	253	16	the	the	DT
cord-263699-gosqpg3k	253	17	RNPs	rnp	NNS
cord-263699-gosqpg3k	253	18	are	be	VBP
cord-263699-gosqpg3k	253	19	then	then	RB
cord-263699-gosqpg3k	253	20	imported	import	VBN
cord-263699-gosqpg3k	253	21	to	to	IN
cord-263699-gosqpg3k	253	22	the	the	DT
cord-263699-gosqpg3k	253	23	cell	cell	NN
cord-263699-gosqpg3k	253	24	nucleus	nucleus	NN
cord-263699-gosqpg3k	253	25	,	,	,
cord-263699-gosqpg3k	253	26	where	where	WRB
cord-263699-gosqpg3k	253	27	the	the	DT
cord-263699-gosqpg3k	253	28	viral	viral	JJ
cord-263699-gosqpg3k	253	29	RdRp	RdRp	NNP
cord-263699-gosqpg3k	253	30	synthesizes	synthesize	VBZ
cord-263699-gosqpg3k	253	31	the	the	DT
cord-263699-gosqpg3k	253	32	mRNAs	mRNAs	NNPS
cord-263699-gosqpg3k	253	33	that	that	WDT
cord-263699-gosqpg3k	253	34	direct	direct	VBP
cord-263699-gosqpg3k	253	35	the	the	DT
cord-263699-gosqpg3k	253	36	synthesis	synthesis	NN
cord-263699-gosqpg3k	253	37	of	of	IN
cord-263699-gosqpg3k	253	38	the	the	DT
cord-263699-gosqpg3k	253	39	viral	viral	JJ
cord-263699-gosqpg3k	253	40	proteins	protein	NNS
cord-263699-gosqpg3k	253	41	in	in	IN
cord-263699-gosqpg3k	253	42	the	the	DT
cord-263699-gosqpg3k	253	43	cytoplasm	cytoplasm	NN
cord-263699-gosqpg3k	253	44	of	of	IN
cord-263699-gosqpg3k	253	45	the	the	DT
cord-263699-gosqpg3k	253	46	cell	cell	NN
cord-263699-gosqpg3k	253	47	.	.	.
cord-263699-gosqpg3k	254	1	During	during	IN
cord-263699-gosqpg3k	254	2	their	-PRON-	PRP$
cord-263699-gosqpg3k	254	3	synthesis	synthesis	NN
cord-263699-gosqpg3k	254	4	,	,	,
cord-263699-gosqpg3k	254	5	the	the	DT
cord-263699-gosqpg3k	254	6	proteins	protein	NNS
cord-263699-gosqpg3k	254	7	HA	HA	NNP
cord-263699-gosqpg3k	254	8	,	,	,
cord-263699-gosqpg3k	254	9	NA	NA	NNP
cord-263699-gosqpg3k	254	10	,	,	,
cord-263699-gosqpg3k	254	11	and	and	CC
cord-263699-gosqpg3k	254	12	M2	M2	NNP
cord-263699-gosqpg3k	254	13	are	be	VBP
cord-263699-gosqpg3k	254	14	inserted	insert	VBN
cord-263699-gosqpg3k	254	15	into	into	IN
cord-263699-gosqpg3k	254	16	the	the	DT
cord-263699-gosqpg3k	254	17	ER	ER	NNP
cord-263699-gosqpg3k	254	18	membrane	membrane	NN
cord-263699-gosqpg3k	254	19	,	,	,
cord-263699-gosqpg3k	254	20	and	and	CC
cord-263699-gosqpg3k	254	21	are	be	VBP
cord-263699-gosqpg3k	254	22	transported	transport	VBN
cord-263699-gosqpg3k	254	23	to	to	IN
cord-263699-gosqpg3k	254	24	the	the	DT
cord-263699-gosqpg3k	254	25	sites	site	NNS
cord-263699-gosqpg3k	254	26	of	of	IN
cord-263699-gosqpg3k	254	27	viral	viral	JJ
cord-263699-gosqpg3k	254	28	assembly	assembly	NN
cord-263699-gosqpg3k	254	29	in	in	IN
cord-263699-gosqpg3k	254	30	the	the	DT
cord-263699-gosqpg3k	254	31	plasma	plasma	NN
cord-263699-gosqpg3k	254	32	membrane	membrane	NN
cord-263699-gosqpg3k	254	33	.	.	.
cord-263699-gosqpg3k	255	1	Concomitant	concomitant	JJ
cord-263699-gosqpg3k	255	2	with	with	IN
cord-263699-gosqpg3k	255	3	this	this	DT
cord-263699-gosqpg3k	255	4	process	process	NN
cord-263699-gosqpg3k	255	5	,	,	,
cord-263699-gosqpg3k	255	6	the	the	DT
cord-263699-gosqpg3k	255	7	NP	NP	NNP
cord-263699-gosqpg3k	255	8	,	,	,
cord-263699-gosqpg3k	255	9	PA	PA	NNP
cord-263699-gosqpg3k	255	10	,	,	,
cord-263699-gosqpg3k	255	11	PB1	PB1	NNP
cord-263699-gosqpg3k	255	12	,	,	,
cord-263699-gosqpg3k	255	13	and	and	CC
cord-263699-gosqpg3k	255	14	PB2	pb2	NN
cord-263699-gosqpg3k	255	15	proteins	protein	NNS
cord-263699-gosqpg3k	255	16	are	be	VBP
cord-263699-gosqpg3k	255	17	imported	import	VBN
cord-263699-gosqpg3k	255	18	into	into	IN
cord-263699-gosqpg3k	255	19	the	the	DT
cord-263699-gosqpg3k	255	20	nucleus	nucleus	NN
cord-263699-gosqpg3k	255	21	and	and	CC
cord-263699-gosqpg3k	255	22	bind	bind	VB
cord-263699-gosqpg3k	255	23	the	the	DT
cord-263699-gosqpg3k	255	24	newly	newly	RB
cord-263699-gosqpg3k	255	25	synthesized	synthesize	VBN
cord-263699-gosqpg3k	255	26	RNA	rna	NN
cord-263699-gosqpg3k	255	27	genome	genome	NN
cord-263699-gosqpg3k	255	28	segments	segment	NNS
cord-263699-gosqpg3k	255	29	to	to	TO
cord-263699-gosqpg3k	255	30	form	form	VB
cord-263699-gosqpg3k	255	31	the	the	DT
cord-263699-gosqpg3k	255	32	novel	novel	JJ
cord-263699-gosqpg3k	255	33	RNPs	rnp	NNS
cord-263699-gosqpg3k	255	34	that	that	WDT
cord-263699-gosqpg3k	255	35	are	be	VBP
cord-263699-gosqpg3k	255	36	then	then	RB
cord-263699-gosqpg3k	255	37	exported	export	VBN
cord-263699-gosqpg3k	255	38	to	to	IN
cord-263699-gosqpg3k	255	39	the	the	DT
cord-263699-gosqpg3k	255	40	cytoplasm	cytoplasm	NN
cord-263699-gosqpg3k	255	41	and	and	CC
cord-263699-gosqpg3k	255	42	subsequently	subsequently	RB
cord-263699-gosqpg3k	255	43	transported	transport	VBN
cord-263699-gosqpg3k	255	44	to	to	IN
cord-263699-gosqpg3k	255	45	the	the	DT
cord-263699-gosqpg3k	255	46	sites	site	NNS
cord-263699-gosqpg3k	255	47	of	of	IN
cord-263699-gosqpg3k	255	48	viral	viral	JJ
cord-263699-gosqpg3k	255	49	assembly	assembly	NN
cord-263699-gosqpg3k	255	50	in	in	IN
cord-263699-gosqpg3k	255	51	the	the	DT
cord-263699-gosqpg3k	255	52	plasma	plasma	NN
cord-263699-gosqpg3k	255	53	membrane	membrane	NN
cord-263699-gosqpg3k	255	54	.	.	.
cord-263699-gosqpg3k	256	1	Finally	finally	RB
cord-263699-gosqpg3k	256	2	,	,	,
cord-263699-gosqpg3k	256	3	the	the	DT
cord-263699-gosqpg3k	256	4	budding	budding	NN
cord-263699-gosqpg3k	256	5	of	of	IN
cord-263699-gosqpg3k	256	6	RNPs	rnp	NNS
cord-263699-gosqpg3k	256	7	in	in	IN
cord-263699-gosqpg3k	256	8	the	the	DT
cord-263699-gosqpg3k	256	9	enriched	enrich	VBN
cord-263699-gosqpg3k	256	10	HA	HA	NNP
cord-263699-gosqpg3k	256	11	,	,	,
cord-263699-gosqpg3k	256	12	NA	NA	NNP
cord-263699-gosqpg3k	256	13	,	,	,
cord-263699-gosqpg3k	256	14	and	and	CC
cord-263699-gosqpg3k	256	15	M2	m2	JJ
cord-263699-gosqpg3k	256	16	membrane	membrane	NN
cord-263699-gosqpg3k	256	17	sites	site	NNS
cord-263699-gosqpg3k	256	18	produces	produce	VBZ
cord-263699-gosqpg3k	256	19	the	the	DT
cord-263699-gosqpg3k	256	20	new	new	JJ
cord-263699-gosqpg3k	256	21	influenza	influenza	NN
cord-263699-gosqpg3k	256	22	virus	virus	NN
cord-263699-gosqpg3k	256	23	infectious	infectious	JJ
cord-263699-gosqpg3k	256	24	particles	particle	NNS
cord-263699-gosqpg3k	256	25	[	[	-LRB-
cord-263699-gosqpg3k	256	26	132	132	CD
cord-263699-gosqpg3k	256	27	,	,	,
cord-263699-gosqpg3k	256	28	133	133	CD
cord-263699-gosqpg3k	256	29	]	]	-RRB-
cord-263699-gosqpg3k	256	30	.	.	.
cord-263699-gosqpg3k	257	1	Two	two	CD
cord-263699-gosqpg3k	257	2	models	model	NNS
cord-263699-gosqpg3k	257	3	have	have	VBP
cord-263699-gosqpg3k	257	4	been	be	VBN
cord-263699-gosqpg3k	257	5	proposed	propose	VBN
cord-263699-gosqpg3k	257	6	to	to	TO
cord-263699-gosqpg3k	257	7	explain	explain	VB
cord-263699-gosqpg3k	257	8	the	the	DT
cord-263699-gosqpg3k	257	9	RNP	RNP	NNP
cord-263699-gosqpg3k	257	10	traffic	traffic	NN
cord-263699-gosqpg3k	257	11	to	to	IN
cord-263699-gosqpg3k	257	12	the	the	DT
cord-263699-gosqpg3k	257	13	plasma	plasma	NN
cord-263699-gosqpg3k	257	14	membrane	membrane	NN
cord-263699-gosqpg3k	257	15	,	,	,
cord-263699-gosqpg3k	257	16	and	and	CC
cord-263699-gosqpg3k	257	17	in	in	IN
cord-263699-gosqpg3k	257	18	both	both	DT
cord-263699-gosqpg3k	257	19	cases	case	NNS
cord-263699-gosqpg3k	257	20	the	the	DT
cord-263699-gosqpg3k	257	21	interaction	interaction	NN
cord-263699-gosqpg3k	257	22	of	of	IN
cord-263699-gosqpg3k	257	23	the	the	DT
cord-263699-gosqpg3k	257	24	RNPs	rnp	NNS
cord-263699-gosqpg3k	257	25	with	with	IN
cord-263699-gosqpg3k	257	26	Rab11	Rab11	NNP
cord-263699-gosqpg3k	257	27	is	be	VBZ
cord-263699-gosqpg3k	257	28	involved	involve	VBN
cord-263699-gosqpg3k	257	29	[	[	-LRB-
cord-263699-gosqpg3k	257	30	134	134	CD
cord-263699-gosqpg3k	257	31	]	]	-RRB-
cord-263699-gosqpg3k	257	32	[	[	-LRB-
cord-263699-gosqpg3k	257	33	135	135	CD
cord-263699-gosqpg3k	257	34	]	]	-RRB-
cord-263699-gosqpg3k	257	35	[	[	-LRB-
cord-263699-gosqpg3k	257	36	136	136	CD
cord-263699-gosqpg3k	257	37	]	]	-RRB-
cord-263699-gosqpg3k	257	38	.	.	.
cord-263699-gosqpg3k	258	1	Recently	recently	RB
cord-263699-gosqpg3k	258	2	,	,	,
cord-263699-gosqpg3k	258	3	it	-PRON-	PRP
cord-263699-gosqpg3k	258	4	was	be	VBD
cord-263699-gosqpg3k	258	5	also	also	RB
cord-263699-gosqpg3k	258	6	reported	report	VBN
cord-263699-gosqpg3k	258	7	that	that	IN
cord-263699-gosqpg3k	258	8	,	,	,
cord-263699-gosqpg3k	258	9	in	in	IN
cord-263699-gosqpg3k	258	10	addition	addition	NN
cord-263699-gosqpg3k	258	11	to	to	IN
cord-263699-gosqpg3k	258	12	Rab11	Rab11	NNP
cord-263699-gosqpg3k	258	13	,	,	,
cord-263699-gosqpg3k	258	14	the	the	DT
cord-263699-gosqpg3k	258	15	activity	activity	NN
cord-263699-gosqpg3k	258	16	of	of	IN
cord-263699-gosqpg3k	258	17	GBF1	GBF1	NNP
cord-263699-gosqpg3k	258	18	was	be	VBD
cord-263699-gosqpg3k	258	19	important	important	JJ
cord-263699-gosqpg3k	258	20	for	for	IN
cord-263699-gosqpg3k	258	21	the	the	DT
cord-263699-gosqpg3k	258	22	assembly	assembly	NN
cord-263699-gosqpg3k	258	23	process	process	NN
cord-263699-gosqpg3k	258	24	of	of	IN
cord-263699-gosqpg3k	258	25	influenza	influenza	NN
cord-263699-gosqpg3k	258	26	A	a	DT
cord-263699-gosqpg3k	258	27	virus	virus	NN
cord-263699-gosqpg3k	258	28	(	(	-LRB-
cord-263699-gosqpg3k	258	29	IAV	IAV	NNP
cord-263699-gosqpg3k	258	30	)	)	-RRB-
cord-263699-gosqpg3k	258	31	[	[	-LRB-
cord-263699-gosqpg3k	258	32	73	73	CD
cord-263699-gosqpg3k	258	33	,	,	,
cord-263699-gosqpg3k	258	34	74	74	CD
cord-263699-gosqpg3k	258	35	,	,	,
cord-263699-gosqpg3k	258	36	137	137	CD
cord-263699-gosqpg3k	258	37	]	]	-RRB-
cord-263699-gosqpg3k	258	38	.	.	.
cord-263699-gosqpg3k	259	1	The	the	DT
cord-263699-gosqpg3k	259	2	block	block	NN
cord-263699-gosqpg3k	259	3	on	on	IN
cord-263699-gosqpg3k	259	4	IAV	IAV	NNP
cord-263699-gosqpg3k	259	5	assembly	assembly	NN
cord-263699-gosqpg3k	259	6	was	be	VBD
cord-263699-gosqpg3k	259	7	found	find	VBN
cord-263699-gosqpg3k	259	8	to	to	TO
cord-263699-gosqpg3k	259	9	be	be	VB
cord-263699-gosqpg3k	259	10	related	relate	VBN
cord-263699-gosqpg3k	259	11	with	with	IN
cord-263699-gosqpg3k	259	12	a	a	DT
cord-263699-gosqpg3k	259	13	decrement	decrement	NN
cord-263699-gosqpg3k	259	14	on	on	IN
cord-263699-gosqpg3k	259	15	the	the	DT
cord-263699-gosqpg3k	259	16	cell	cell	NN
cord-263699-gosqpg3k	259	17	surface	surface	NN
cord-263699-gosqpg3k	259	18	of	of	IN
cord-263699-gosqpg3k	259	19	the	the	DT
cord-263699-gosqpg3k	259	20	HA	HA	NNP
cord-263699-gosqpg3k	259	21	,	,	,
cord-263699-gosqpg3k	259	22	NA	NA	NNP
cord-263699-gosqpg3k	259	23	,	,	,
cord-263699-gosqpg3k	259	24	and	and	CC
cord-263699-gosqpg3k	259	25	M2	m2	JJ
cord-263699-gosqpg3k	259	26	viral	viral	JJ
cord-263699-gosqpg3k	259	27	proteins	protein	NNS
cord-263699-gosqpg3k	259	28	,	,	,
cord-263699-gosqpg3k	259	29	as	as	RB
cord-263699-gosqpg3k	259	30	well	well	RB
cord-263699-gosqpg3k	259	31	as	as	IN
cord-263699-gosqpg3k	259	32	with	with	IN
cord-263699-gosqpg3k	259	33	disruption	disruption	NN
cord-263699-gosqpg3k	259	34	of	of	IN
cord-263699-gosqpg3k	259	35	the	the	DT
cord-263699-gosqpg3k	259	36	transport	transport	NN
cord-263699-gosqpg3k	259	37	of	of	IN
cord-263699-gosqpg3k	259	38	RNPs	rnp	NNS
cord-263699-gosqpg3k	259	39	to	to	IN
cord-263699-gosqpg3k	259	40	the	the	DT
cord-263699-gosqpg3k	259	41	plasma	plasma	NN
cord-263699-gosqpg3k	259	42	membrane	membrane	NN
cord-263699-gosqpg3k	259	43	[	[	-LRB-
cord-263699-gosqpg3k	259	44	73	73	CD
cord-263699-gosqpg3k	259	45	]	]	-RRB-
cord-263699-gosqpg3k	259	46	[	[	-LRB-
cord-263699-gosqpg3k	259	47	74	74	CD
cord-263699-gosqpg3k	259	48	]	]	-RRB-
cord-263699-gosqpg3k	259	49	[	[	-LRB-
cord-263699-gosqpg3k	259	50	75	75	CD
cord-263699-gosqpg3k	259	51	]	]	-RRB-
cord-263699-gosqpg3k	259	52	137	137	CD
cord-263699-gosqpg3k	259	53	]	]	-RRB-
cord-263699-gosqpg3k	259	54	,	,	,
cord-263699-gosqpg3k	259	55	indicating	indicate	VBG
cord-263699-gosqpg3k	259	56	that	that	IN
cord-263699-gosqpg3k	259	57	GBF1	GBF1	NNP
cord-263699-gosqpg3k	259	58	facilitates	facilitate	VBZ
cord-263699-gosqpg3k	259	59	the	the	DT
cord-263699-gosqpg3k	259	60	assembly	assembly	NN
cord-263699-gosqpg3k	259	61	of	of	IN
cord-263699-gosqpg3k	259	62	IAV	IAV	NNP
cord-263699-gosqpg3k	259	63	by	by	IN
cord-263699-gosqpg3k	259	64	regulating	regulate	VBG
cord-263699-gosqpg3k	259	65	the	the	DT
cord-263699-gosqpg3k	259	66	transport	transport	NN
cord-263699-gosqpg3k	259	67	to	to	IN
cord-263699-gosqpg3k	259	68	the	the	DT
cord-263699-gosqpg3k	259	69	plasma	plasma	NN
cord-263699-gosqpg3k	259	70	membrane	membrane	NN
cord-263699-gosqpg3k	259	71	of	of	IN
cord-263699-gosqpg3k	259	72	the	the	DT
cord-263699-gosqpg3k	259	73	viral	viral	JJ
cord-263699-gosqpg3k	259	74	elements	element	NNS
cord-263699-gosqpg3k	259	75	that	that	WDT
cord-263699-gosqpg3k	259	76	form	form	VBP
cord-263699-gosqpg3k	259	77	the	the	DT
cord-263699-gosqpg3k	259	78	IAV	IAV	NNP
cord-263699-gosqpg3k	259	79	virion	virion	NN
cord-263699-gosqpg3k	259	80	.	.	.
cord-263699-gosqpg3k	260	1	Besides	besides	IN
cord-263699-gosqpg3k	260	2	its	-PRON-	PRP$
cord-263699-gosqpg3k	260	3	role	role	NN
cord-263699-gosqpg3k	260	4	in	in	IN
cord-263699-gosqpg3k	260	5	regulating	regulate	VBG
cord-263699-gosqpg3k	260	6	the	the	DT
cord-263699-gosqpg3k	260	7	transport	transport	NN
cord-263699-gosqpg3k	260	8	of	of	IN
cord-263699-gosqpg3k	260	9	viral	viral	JJ
cord-263699-gosqpg3k	260	10	proteins	protein	NNS
cord-263699-gosqpg3k	260	11	to	to	IN
cord-263699-gosqpg3k	260	12	the	the	DT
cord-263699-gosqpg3k	260	13	plasma	plasma	NN
cord-263699-gosqpg3k	260	14	membrane	membrane	NN
cord-263699-gosqpg3k	260	15	,	,	,
cord-263699-gosqpg3k	260	16	it	-PRON-	PRP
cord-263699-gosqpg3k	260	17	has	have	VBZ
cord-263699-gosqpg3k	260	18	been	be	VBN
cord-263699-gosqpg3k	260	19	shown	show	VBN
cord-263699-gosqpg3k	260	20	that	that	IN
cord-263699-gosqpg3k	260	21	GBF1	GBF1	NNP
cord-263699-gosqpg3k	260	22	interacts	interact	VBZ
cord-263699-gosqpg3k	260	23	specifically	specifically	RB
cord-263699-gosqpg3k	260	24	with	with	IN
cord-263699-gosqpg3k	260	25	the	the	DT
cord-263699-gosqpg3k	260	26	protein	protein	NN
cord-263699-gosqpg3k	260	27	M2	m2	NN
cord-263699-gosqpg3k	260	28	[	[	-LRB-
cord-263699-gosqpg3k	260	29	74	74	CD
cord-263699-gosqpg3k	260	30	]	]	-RRB-
cord-263699-gosqpg3k	260	31	.	.	.
cord-263699-gosqpg3k	261	1	Although	although	IN
cord-263699-gosqpg3k	261	2	the	the	DT
cord-263699-gosqpg3k	261	3	biological	biological	JJ
cord-263699-gosqpg3k	261	4	importance	importance	NN
cord-263699-gosqpg3k	261	5	of	of	IN
cord-263699-gosqpg3k	261	6	this	this	DT
cord-263699-gosqpg3k	261	7	interaction	interaction	NN
cord-263699-gosqpg3k	261	8	is	be	VBZ
cord-263699-gosqpg3k	261	9	unknown	unknown	JJ
cord-263699-gosqpg3k	261	10	,	,	,
cord-263699-gosqpg3k	261	11	the	the	DT
cord-263699-gosqpg3k	261	12	observation	observation	NN
cord-263699-gosqpg3k	261	13	that	that	WDT
cord-263699-gosqpg3k	261	14	IAV	IAV	NNP
cord-263699-gosqpg3k	261	15	induces	induce	VBZ
cord-263699-gosqpg3k	261	16	the	the	DT
cord-263699-gosqpg3k	261	17	disruption	disruption	NN
cord-263699-gosqpg3k	261	18	of	of	IN
cord-263699-gosqpg3k	261	19	the	the	DT
cord-263699-gosqpg3k	261	20	Golgi	Golgi	NNP
cord-263699-gosqpg3k	261	21	apparatus	apparatus	NN
cord-263699-gosqpg3k	261	22	[	[	-LRB-
cord-263699-gosqpg3k	261	23	75	75	CD
cord-263699-gosqpg3k	261	24	]	]	-RRB-
cord-263699-gosqpg3k	261	25	makes	make	VBZ
cord-263699-gosqpg3k	261	26	it	-PRON-	PRP
cord-263699-gosqpg3k	261	27	possible	possible	JJ
cord-263699-gosqpg3k	261	28	that	that	IN
cord-263699-gosqpg3k	261	29	through	through	IN
cord-263699-gosqpg3k	261	30	the	the	DT
cord-263699-gosqpg3k	261	31	M2-GBF1	M2-GBF1	NNP
cord-263699-gosqpg3k	261	32	interaction	interaction	NN
cord-263699-gosqpg3k	261	33	the	the	DT
cord-263699-gosqpg3k	261	34	GBF1	GBF1	NNP
cord-263699-gosqpg3k	261	35	is	be	VBZ
cord-263699-gosqpg3k	261	36	hijacked	hijack	VBN
cord-263699-gosqpg3k	261	37	from	from	IN
cord-263699-gosqpg3k	261	38	the	the	DT
cord-263699-gosqpg3k	261	39	secretory	secretory	JJ
cord-263699-gosqpg3k	261	40	pathway	pathway	NN
cord-263699-gosqpg3k	261	41	(	(	-LRB-
cord-263699-gosqpg3k	261	42	as	as	IN
cord-263699-gosqpg3k	261	43	observed	observe	VBN
cord-263699-gosqpg3k	261	44	for	for	IN
cord-263699-gosqpg3k	261	45	the	the	DT
cord-263699-gosqpg3k	261	46	3A	3A	NNP
cord-263699-gosqpg3k	261	47	protein	protein	NN
cord-263699-gosqpg3k	261	48	of	of	IN
cord-263699-gosqpg3k	261	49	picornavirus	picornavirus	NNP
cord-263699-gosqpg3k	261	50	)	)	-RRB-
cord-263699-gosqpg3k	261	51	,	,	,
cord-263699-gosqpg3k	261	52	to	to	TO
cord-263699-gosqpg3k	261	53	promote	promote	VB
cord-263699-gosqpg3k	261	54	the	the	DT
cord-263699-gosqpg3k	261	55	transport	transport	NN
cord-263699-gosqpg3k	261	56	of	of	IN
cord-263699-gosqpg3k	261	57	HA	HA	NNP
cord-263699-gosqpg3k	261	58	,	,	,
cord-263699-gosqpg3k	261	59	NA	NA	NNP
cord-263699-gosqpg3k	261	60	,	,	,
cord-263699-gosqpg3k	261	61	M2	M2	NNP
cord-263699-gosqpg3k	261	62	proteins	protein	NNS
cord-263699-gosqpg3k	261	63	,	,	,
cord-263699-gosqpg3k	261	64	and	and	CC
cord-263699-gosqpg3k	261	65	the	the	DT
cord-263699-gosqpg3k	261	66	RNPs	rnp	NNS
cord-263699-gosqpg3k	261	67	.	.	.
cord-263699-gosqpg3k	262	1	Moreover	moreover	RB
cord-263699-gosqpg3k	262	2	,	,	,
cord-263699-gosqpg3k	262	3	the	the	DT
cord-263699-gosqpg3k	262	4	observation	observation	NN
cord-263699-gosqpg3k	262	5	that	that	IN
cord-263699-gosqpg3k	262	6	the	the	DT
cord-263699-gosqpg3k	262	7	inhibition	inhibition	NN
cord-263699-gosqpg3k	262	8	of	of	IN
cord-263699-gosqpg3k	262	9	RNP	RNP	NNP
cord-263699-gosqpg3k	262	10	transport	transport	NN
cord-263699-gosqpg3k	262	11	by	by	IN
cord-263699-gosqpg3k	262	12	BFA	BFA	NNP
cord-263699-gosqpg3k	262	13	induces	induce	VBZ
cord-263699-gosqpg3k	262	14	the	the	DT
cord-263699-gosqpg3k	262	15	accumulation	accumulation	NN
cord-263699-gosqpg3k	262	16	of	of	IN
cord-263699-gosqpg3k	262	17	RNPs	rnp	NNS
cord-263699-gosqpg3k	262	18	in	in	IN
cord-263699-gosqpg3k	262	19	tubulated	tubulated	JJ
cord-263699-gosqpg3k	262	20	structures	structure	NNS
cord-263699-gosqpg3k	262	21	in	in	IN
cord-263699-gosqpg3k	262	22	the	the	DT
cord-263699-gosqpg3k	262	23	perinuclear	perinuclear	JJ
cord-263699-gosqpg3k	262	24	region	region	NN
cord-263699-gosqpg3k	262	25	[	[	-LRB-
cord-263699-gosqpg3k	262	26	137	137	CD
cord-263699-gosqpg3k	262	27	]	]	-RRB-
cord-263699-gosqpg3k	262	28	,	,	,
cord-263699-gosqpg3k	262	29	suggest	suggest	VBP
cord-263699-gosqpg3k	262	30	that	that	IN
cord-263699-gosqpg3k	262	31	M2	M2	NNP
cord-263699-gosqpg3k	262	32	might	may	MD
cord-263699-gosqpg3k	262	33	recruit	recruit	VB
cord-263699-gosqpg3k	262	34	GBF1	GBF1	NNP
cord-263699-gosqpg3k	262	35	from	from	IN
cord-263699-gosqpg3k	262	36	the	the	DT
cord-263699-gosqpg3k	262	37	Golgi	Golgi	NNP
cord-263699-gosqpg3k	262	38	apparatus	apparatus	NN
cord-263699-gosqpg3k	262	39	to	to	IN
cord-263699-gosqpg3k	262	40	the	the	DT
cord-263699-gosqpg3k	262	41	tubulate	tubulate	JJ
cord-263699-gosqpg3k	262	42	ER	ER	NNP
cord-263699-gosqpg3k	262	43	network	network	NN
cord-263699-gosqpg3k	262	44	to	to	TO
cord-263699-gosqpg3k	262	45	promote	promote	VB
cord-263699-gosqpg3k	262	46	the	the	DT
cord-263699-gosqpg3k	262	47	transport	transport	NN
cord-263699-gosqpg3k	262	48	of	of	IN
cord-263699-gosqpg3k	262	49	HA	HA	NNP
cord-263699-gosqpg3k	262	50	,	,	,
cord-263699-gosqpg3k	262	51	NA	NA	NNP
cord-263699-gosqpg3k	262	52	,	,	,
cord-263699-gosqpg3k	262	53	M2	M2	NNP
cord-263699-gosqpg3k	262	54	,	,	,
cord-263699-gosqpg3k	262	55	and	and	CC
cord-263699-gosqpg3k	262	56	RNPs	rnp	NNS
cord-263699-gosqpg3k	262	57	to	to	IN
cord-263699-gosqpg3k	262	58	the	the	DT
cord-263699-gosqpg3k	262	59	plasma	plasma	NN
cord-263699-gosqpg3k	262	60	membrane	membrane	NN
cord-263699-gosqpg3k	262	61	.	.	.
cord-263699-gosqpg3k	263	1	In	in	IN
cord-263699-gosqpg3k	263	2	support	support	NN
cord-263699-gosqpg3k	263	3	of	of	IN
cord-263699-gosqpg3k	263	4	the	the	DT
cord-263699-gosqpg3k	263	5	role	role	NN
cord-263699-gosqpg3k	263	6	of	of	IN
cord-263699-gosqpg3k	263	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	263	8	to	to	TO
cord-263699-gosqpg3k	263	9	stimulate	stimulate	VB
cord-263699-gosqpg3k	263	10	the	the	DT
cord-263699-gosqpg3k	263	11	transport	transport	NN
cord-263699-gosqpg3k	263	12	of	of	IN
cord-263699-gosqpg3k	263	13	these	these	DT
cord-263699-gosqpg3k	263	14	viral	viral	JJ
cord-263699-gosqpg3k	263	15	elements	element	NNS
cord-263699-gosqpg3k	263	16	,	,	,
cord-263699-gosqpg3k	263	17	it	-PRON-	PRP
cord-263699-gosqpg3k	263	18	has	have	VBZ
cord-263699-gosqpg3k	263	19	been	be	VBN
cord-263699-gosqpg3k	263	20	found	find	VBN
cord-263699-gosqpg3k	263	21	that	that	IN
cord-263699-gosqpg3k	263	22	Arf1	Arf1	NNP
cord-263699-gosqpg3k	263	23	can	can	MD
cord-263699-gosqpg3k	263	24	colocalize	colocalize	VB
cord-263699-gosqpg3k	263	25	with	with	IN
cord-263699-gosqpg3k	263	26	RNPs	rnp	NNS
cord-263699-gosqpg3k	263	27	of	of	IN
cord-263699-gosqpg3k	263	28	IAV	IAV	NNP
cord-263699-gosqpg3k	263	29	[	[	-LRB-
cord-263699-gosqpg3k	263	30	75	75	CD
cord-263699-gosqpg3k	263	31	]	]	-RRB-
cord-263699-gosqpg3k	263	32	,	,	,
cord-263699-gosqpg3k	263	33	suggesting	suggest	VBG
cord-263699-gosqpg3k	263	34	that	that	IN
cord-263699-gosqpg3k	263	35	GBF1	GBF1	NNP
cord-263699-gosqpg3k	263	36	might	may	MD
cord-263699-gosqpg3k	263	37	mediate	mediate	VB
cord-263699-gosqpg3k	263	38	the	the	DT
cord-263699-gosqpg3k	263	39	traffic	traffic	NN
cord-263699-gosqpg3k	263	40	of	of	IN
cord-263699-gosqpg3k	263	41	IAV	IAV	NNP
cord-263699-gosqpg3k	263	42	RNPs	rnp	NNS
cord-263699-gosqpg3k	263	43	by	by	IN
cord-263699-gosqpg3k	263	44	maintaining	maintain	VBG
cord-263699-gosqpg3k	263	45	an	an	DT
cord-263699-gosqpg3k	263	46	active	active	JJ
cord-263699-gosqpg3k	263	47	COPI	COPI	NNP
cord-263699-gosqpg3k	263	48	transport	transport	NN
cord-263699-gosqpg3k	263	49	.	.	.
cord-263699-gosqpg3k	264	1	In	in	IN
cord-263699-gosqpg3k	264	2	support	support	NN
cord-263699-gosqpg3k	264	3	of	of	IN
cord-263699-gosqpg3k	264	4	this	this	DT
cord-263699-gosqpg3k	264	5	idea	idea	NN
cord-263699-gosqpg3k	264	6	is	be	VBZ
cord-263699-gosqpg3k	264	7	the	the	DT
cord-263699-gosqpg3k	264	8	discovery	discovery	NN
cord-263699-gosqpg3k	264	9	that	that	WDT
cord-263699-gosqpg3k	264	10	RNPs	RNPs	NNP
cord-263699-gosqpg3k	264	11	travel	travel	NN
cord-263699-gosqpg3k	264	12	to	to	IN
cord-263699-gosqpg3k	264	13	the	the	DT
cord-263699-gosqpg3k	264	14	plasma	plasma	NN
cord-263699-gosqpg3k	264	15	membrane	membrane	NN
cord-263699-gosqpg3k	264	16	in	in	IN
cord-263699-gosqpg3k	264	17	a	a	DT
cord-263699-gosqpg3k	264	18	microtubule	microtubule	JJ
cord-263699-gosqpg3k	264	19	dependent	dependent	JJ
cord-263699-gosqpg3k	264	20	fashion	fashion	NN
cord-263699-gosqpg3k	264	21	[	[	-LRB-
cord-263699-gosqpg3k	264	22	134	134	CD
cord-263699-gosqpg3k	264	23	,	,	,
cord-263699-gosqpg3k	264	24	135	135	CD
cord-263699-gosqpg3k	264	25	]	]	-RRB-
cord-263699-gosqpg3k	264	26	,	,	,
cord-263699-gosqpg3k	264	27	as	as	RB
cord-263699-gosqpg3k	264	28	well	well	RB
cord-263699-gosqpg3k	264	29	as	as	IN
cord-263699-gosqpg3k	264	30	the	the	DT
cord-263699-gosqpg3k	264	31	close	close	JJ
cord-263699-gosqpg3k	264	32	relationship	relationship	NN
cord-263699-gosqpg3k	264	33	between	between	IN
cord-263699-gosqpg3k	264	34	the	the	DT
cord-263699-gosqpg3k	264	35	movement	movement	NN
cord-263699-gosqpg3k	264	36	of	of	IN
cord-263699-gosqpg3k	264	37	COPI	COPI	NNP
cord-263699-gosqpg3k	264	38	vesicles	vesicle	NNS
cord-263699-gosqpg3k	264	39	and	and	CC
cord-263699-gosqpg3k	264	40	microtubules	microtubule	NNS
cord-263699-gosqpg3k	264	41	,	,	,
cord-263699-gosqpg3k	264	42	which	which	WDT
cord-263699-gosqpg3k	264	43	seem	seem	VBP
cord-263699-gosqpg3k	264	44	to	to	TO
cord-263699-gosqpg3k	264	45	indicate	indicate	VB
cord-263699-gosqpg3k	264	46	that	that	IN
cord-263699-gosqpg3k	264	47	COPI	COPI	NNP
cord-263699-gosqpg3k	264	48	vesicles	vesicle	NNS
cord-263699-gosqpg3k	264	49	might	may	MD
cord-263699-gosqpg3k	264	50	be	be	VB
cord-263699-gosqpg3k	264	51	important	important	JJ
cord-263699-gosqpg3k	264	52	to	to	IN
cord-263699-gosqpg3k	264	53	the	the	DT
cord-263699-gosqpg3k	264	54	transport	transport	NN
cord-263699-gosqpg3k	264	55	of	of	IN
cord-263699-gosqpg3k	264	56	RNPs	rnp	NNS
cord-263699-gosqpg3k	264	57	.	.	.
cord-263699-gosqpg3k	265	1	In	in	IN
cord-263699-gosqpg3k	265	2	addition	addition	NN
cord-263699-gosqpg3k	265	3	,	,	,
cord-263699-gosqpg3k	265	4	COPI	COPI	NNP
cord-263699-gosqpg3k	265	5	was	be	VBD
cord-263699-gosqpg3k	265	6	also	also	RB
cord-263699-gosqpg3k	265	7	suggested	suggest	VBN
cord-263699-gosqpg3k	265	8	to	to	TO
cord-263699-gosqpg3k	265	9	be	be	VB
cord-263699-gosqpg3k	265	10	related	relate	VBN
cord-263699-gosqpg3k	265	11	with	with	IN
cord-263699-gosqpg3k	265	12	the	the	DT
cord-263699-gosqpg3k	265	13	internalization	internalization	NN
cord-263699-gosqpg3k	265	14	process	process	NN
cord-263699-gosqpg3k	265	15	of	of	IN
cord-263699-gosqpg3k	265	16	IAV	IAV	NNP
cord-263699-gosqpg3k	265	17	,	,	,
cord-263699-gosqpg3k	265	18	since	since	IN
cord-263699-gosqpg3k	265	19	its	-PRON-	PRP$
cord-263699-gosqpg3k	265	20	depletion	depletion	NN
cord-263699-gosqpg3k	265	21	was	be	VBD
cord-263699-gosqpg3k	265	22	shown	show	VBN
cord-263699-gosqpg3k	265	23	to	to	TO
cord-263699-gosqpg3k	265	24	reduce	reduce	VB
cord-263699-gosqpg3k	265	25	this	this	DT
cord-263699-gosqpg3k	265	26	process	process	NN
cord-263699-gosqpg3k	265	27	[	[	-LRB-
cord-263699-gosqpg3k	265	28	73	73	CD
cord-263699-gosqpg3k	265	29	,	,	,
cord-263699-gosqpg3k	265	30	138	138	CD
cord-263699-gosqpg3k	265	31	]	]	-RRB-
cord-263699-gosqpg3k	265	32	.	.	.
cord-263699-gosqpg3k	266	1	However	however	RB
cord-263699-gosqpg3k	266	2	,	,	,
cord-263699-gosqpg3k	266	3	given	give	VBN
cord-263699-gosqpg3k	266	4	that	that	IN
cord-263699-gosqpg3k	266	5	these	these	DT
cord-263699-gosqpg3k	266	6	results	result	NNS
cord-263699-gosqpg3k	266	7	could	could	MD
cord-263699-gosqpg3k	266	8	not	not	RB
cord-263699-gosqpg3k	266	9	be	be	VB
cord-263699-gosqpg3k	266	10	recapitulated	recapitulate	VBN
cord-263699-gosqpg3k	266	11	by	by	IN
cord-263699-gosqpg3k	266	12	BFA	BFA	NNP
cord-263699-gosqpg3k	266	13	and	and	CC
cord-263699-gosqpg3k	266	14	GCA	GCA	NNP
cord-263699-gosqpg3k	266	15	treatments	treatment	NNS
cord-263699-gosqpg3k	266	16	,	,	,
cord-263699-gosqpg3k	266	17	it	-PRON-	PRP
cord-263699-gosqpg3k	266	18	was	be	VBD
cord-263699-gosqpg3k	266	19	presumed	presume	VBN
cord-263699-gosqpg3k	266	20	that	that	IN
cord-263699-gosqpg3k	266	21	this	this	DT
cord-263699-gosqpg3k	266	22	effect	effect	NN
cord-263699-gosqpg3k	266	23	might	may	MD
cord-263699-gosqpg3k	266	24	be	be	VB
cord-263699-gosqpg3k	266	25	due	due	JJ
cord-263699-gosqpg3k	266	26	to	to	IN
cord-263699-gosqpg3k	266	27	the	the	DT
cord-263699-gosqpg3k	266	28	long	long	JJ
cord-263699-gosqpg3k	266	29	-	-	HYPH
cord-263699-gosqpg3k	266	30	term	term	NN
cord-263699-gosqpg3k	266	31	inhibition	inhibition	NN
cord-263699-gosqpg3k	266	32	of	of	IN
cord-263699-gosqpg3k	266	33	protein	protein	NN
cord-263699-gosqpg3k	266	34	and	and	CC
cord-263699-gosqpg3k	266	35	lipid	lipid	NN
cord-263699-gosqpg3k	266	36	transport	transport	NN
cord-263699-gosqpg3k	266	37	to	to	IN
cord-263699-gosqpg3k	266	38	the	the	DT
cord-263699-gosqpg3k	266	39	plasma	plasma	NN
cord-263699-gosqpg3k	266	40	membrane	membrane	NN
cord-263699-gosqpg3k	266	41	[	[	-LRB-
cord-263699-gosqpg3k	266	42	73	73	CD
cord-263699-gosqpg3k	266	43	]	]	-RRB-
cord-263699-gosqpg3k	266	44	.	.	.
cord-263699-gosqpg3k	267	1	The	the	DT
cord-263699-gosqpg3k	267	2	evaluation	evaluation	NN
cord-263699-gosqpg3k	267	3	of	of	IN
cord-263699-gosqpg3k	267	4	the	the	DT
cord-263699-gosqpg3k	267	5	effects	effect	NNS
cord-263699-gosqpg3k	267	6	of	of	IN
cord-263699-gosqpg3k	267	7	RNAi	RNAi	NNS
cord-263699-gosqpg3k	267	8	depletion	depletion	NN
cord-263699-gosqpg3k	267	9	of	of	IN
cord-263699-gosqpg3k	267	10	COPI	COPI	NNP
cord-263699-gosqpg3k	267	11	on	on	IN
cord-263699-gosqpg3k	267	12	IAV	IAV	NNP
cord-263699-gosqpg3k	267	13	replication	replication	NN
cord-263699-gosqpg3k	267	14	assays	assay	NNS
cord-263699-gosqpg3k	267	15	that	that	WDT
cord-263699-gosqpg3k	267	16	bypass	bypass	VBP
cord-263699-gosqpg3k	267	17	the	the	DT
cord-263699-gosqpg3k	267	18	virus	virus	NN
cord-263699-gosqpg3k	267	19	internalization	internalization	NN
cord-263699-gosqpg3k	267	20	process	process	NN
cord-263699-gosqpg3k	267	21	would	would	MD
cord-263699-gosqpg3k	267	22	help	help	VB
cord-263699-gosqpg3k	267	23	to	to	TO
cord-263699-gosqpg3k	267	24	bring	bring	VB
cord-263699-gosqpg3k	267	25	light	light	NN
cord-263699-gosqpg3k	267	26	into	into	IN
cord-263699-gosqpg3k	267	27	this	this	DT
cord-263699-gosqpg3k	267	28	controversial	controversial	JJ
cord-263699-gosqpg3k	267	29	matter	matter	NN
cord-263699-gosqpg3k	267	30	.	.	.
cord-263699-gosqpg3k	268	1	The	the	DT
cord-263699-gosqpg3k	268	2	participation	participation	NN
cord-263699-gosqpg3k	268	3	of	of	IN
cord-263699-gosqpg3k	268	4	GBF1	GBF1	NNP
cord-263699-gosqpg3k	268	5	in	in	IN
cord-263699-gosqpg3k	268	6	the	the	DT
cord-263699-gosqpg3k	268	7	replication	replication	NN
cord-263699-gosqpg3k	268	8	of	of	IN
cord-263699-gosqpg3k	268	9	negative	negative	JJ
cord-263699-gosqpg3k	268	10	-	-	HYPH
cord-263699-gosqpg3k	268	11	sense	sense	NN
cord-263699-gosqpg3k	268	12	RNA	RNA	NNP
cord-263699-gosqpg3k	268	13	viruses	virus	NNS
cord-263699-gosqpg3k	268	14	is	be	VBZ
cord-263699-gosqpg3k	268	15	not	not	RB
cord-263699-gosqpg3k	268	16	restricted	restrict	VBN
cord-263699-gosqpg3k	268	17	to	to	IN
cord-263699-gosqpg3k	268	18	IAV	IAV	NNP
cord-263699-gosqpg3k	268	19	.	.	.
cord-263699-gosqpg3k	269	1	The	the	DT
cord-263699-gosqpg3k	269	2	replication	replication	NN
cord-263699-gosqpg3k	269	3	of	of	IN
cord-263699-gosqpg3k	269	4	human	human	JJ
cord-263699-gosqpg3k	269	5	parainfluenza	parainfluenza	NNP
cord-263699-gosqpg3k	269	6	virus	virus	NNP
cord-263699-gosqpg3k	269	7	type	type	NNP
cord-263699-gosqpg3k	269	8	3	3	CD
cord-263699-gosqpg3k	269	9	(	(	-LRB-
cord-263699-gosqpg3k	269	10	HPIV3	hpiv3	NN
cord-263699-gosqpg3k	269	11	,	,	,
cord-263699-gosqpg3k	269	12	member	member	NN
cord-263699-gosqpg3k	269	13	of	of	IN
cord-263699-gosqpg3k	269	14	Paramyxoviridae	Paramyxoviridae	NNP
cord-263699-gosqpg3k	269	15	family	family	NN
cord-263699-gosqpg3k	269	16	)	)	-RRB-
cord-263699-gosqpg3k	269	17	,	,	,
cord-263699-gosqpg3k	269	18	as	as	RB
cord-263699-gosqpg3k	269	19	well	well	RB
cord-263699-gosqpg3k	269	20	as	as	IN
cord-263699-gosqpg3k	269	21	that	that	DT
cord-263699-gosqpg3k	269	22	of	of	IN
cord-263699-gosqpg3k	269	23	the	the	DT
cord-263699-gosqpg3k	269	24	lymphocytic	lymphocytic	JJ
cord-263699-gosqpg3k	269	25	choriomeningitis	choriomeningitis	NNP
cord-263699-gosqpg3k	269	26	virus	virus	NN
cord-263699-gosqpg3k	269	27	(	(	-LRB-
cord-263699-gosqpg3k	269	28	LCMV	LCMV	NNP
cord-263699-gosqpg3k	269	29	,	,	,
cord-263699-gosqpg3k	269	30	the	the	DT
cord-263699-gosqpg3k	269	31	prototypic	prototypic	NNP
cord-263699-gosqpg3k	269	32	member	member	NN
cord-263699-gosqpg3k	269	33	of	of	IN
cord-263699-gosqpg3k	269	34	the	the	DT
cord-263699-gosqpg3k	269	35	Arenaviridae	Arenaviridae	NNP
cord-263699-gosqpg3k	269	36	family	family	NN
cord-263699-gosqpg3k	269	37	)	)	-RRB-
cord-263699-gosqpg3k	269	38	have	have	VBP
cord-263699-gosqpg3k	269	39	also	also	RB
cord-263699-gosqpg3k	269	40	shown	show	VBN
cord-263699-gosqpg3k	269	41	to	to	TO
cord-263699-gosqpg3k	269	42	be	be	VB
cord-263699-gosqpg3k	269	43	dependent	dependent	JJ
cord-263699-gosqpg3k	269	44	on	on	IN
cord-263699-gosqpg3k	269	45	the	the	DT
cord-263699-gosqpg3k	269	46	GBF1	GBF1	NNP
cord-263699-gosqpg3k	269	47	activity	activity	NN
cord-263699-gosqpg3k	269	48	.	.	.
cord-263699-gosqpg3k	270	1	Depletion	depletion	NN
cord-263699-gosqpg3k	270	2	of	of	IN
cord-263699-gosqpg3k	270	3	this	this	DT
cord-263699-gosqpg3k	270	4	factor	factor	NN
cord-263699-gosqpg3k	270	5	by	by	IN
cord-263699-gosqpg3k	270	6	RNAi	RNAi	NNS
cord-263699-gosqpg3k	270	7	or	or	CC
cord-263699-gosqpg3k	270	8	its	-PRON-	PRP$
cord-263699-gosqpg3k	270	9	pharmacological	pharmacological	JJ
cord-263699-gosqpg3k	270	10	inhibition	inhibition	NN
cord-263699-gosqpg3k	270	11	by	by	IN
cord-263699-gosqpg3k	270	12	BFA	BFA	NNP
cord-263699-gosqpg3k	270	13	or	or	CC
cord-263699-gosqpg3k	270	14	GCA	GCA	NNP
cord-263699-gosqpg3k	270	15	,	,	,
cord-263699-gosqpg3k	270	16	has	have	VBZ
cord-263699-gosqpg3k	270	17	shown	show	VBN
cord-263699-gosqpg3k	270	18	to	to	TO
cord-263699-gosqpg3k	270	19	significantly	significantly	RB
cord-263699-gosqpg3k	270	20	reduce	reduce	VB
cord-263699-gosqpg3k	270	21	the	the	DT
cord-263699-gosqpg3k	270	22	protein	protein	NN
cord-263699-gosqpg3k	270	23	synthesis	synthesis	NN
cord-263699-gosqpg3k	270	24	of	of	IN
cord-263699-gosqpg3k	270	25	these	these	DT
cord-263699-gosqpg3k	270	26	viruses	virus	NNS
cord-263699-gosqpg3k	270	27	[	[	-LRB-
cord-263699-gosqpg3k	270	28	72	72	CD
cord-263699-gosqpg3k	270	29	]	]	-RRB-
cord-263699-gosqpg3k	270	30	.	.	.
cord-263699-gosqpg3k	271	1	However	however	RB
cord-263699-gosqpg3k	271	2	,	,	,
cord-263699-gosqpg3k	271	3	whether	whether	IN
cord-263699-gosqpg3k	271	4	the	the	DT
cord-263699-gosqpg3k	271	5	role	role	NN
cord-263699-gosqpg3k	271	6	of	of	IN
cord-263699-gosqpg3k	271	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	271	8	might	may	MD
cord-263699-gosqpg3k	271	9	be	be	VB
cord-263699-gosqpg3k	271	10	related	relate	VBN
cord-263699-gosqpg3k	271	11	directly	directly	RB
cord-263699-gosqpg3k	271	12	to	to	IN
cord-263699-gosqpg3k	271	13	viral	viral	JJ
cord-263699-gosqpg3k	271	14	protein	protein	NN
cord-263699-gosqpg3k	271	15	synthesis	synthesis	NN
cord-263699-gosqpg3k	271	16	or	or	CC
cord-263699-gosqpg3k	271	17	results	result	NNS
cord-263699-gosqpg3k	271	18	from	from	IN
cord-263699-gosqpg3k	271	19	defects	defect	NNS
cord-263699-gosqpg3k	271	20	in	in	IN
cord-263699-gosqpg3k	271	21	the	the	DT
cord-263699-gosqpg3k	271	22	previous	previous	JJ
cord-263699-gosqpg3k	271	23	steps	step	NNS
cord-263699-gosqpg3k	271	24	of	of	IN
cord-263699-gosqpg3k	271	25	the	the	DT
cord-263699-gosqpg3k	271	26	viral	viral	JJ
cord-263699-gosqpg3k	271	27	cycle	cycle	NN
cord-263699-gosqpg3k	271	28	,	,	,
cord-263699-gosqpg3k	271	29	remains	remain	VBZ
cord-263699-gosqpg3k	271	30	to	to	TO
cord-263699-gosqpg3k	271	31	be	be	VB
cord-263699-gosqpg3k	271	32	elucidated	elucidate	VBN
cord-263699-gosqpg3k	271	33	.	.	.
cord-263699-gosqpg3k	272	1	On	on	IN
cord-263699-gosqpg3k	272	2	the	the	DT
cord-263699-gosqpg3k	272	3	other	other	JJ
cord-263699-gosqpg3k	272	4	hand	hand	NN
cord-263699-gosqpg3k	272	5	,	,	,
cord-263699-gosqpg3k	272	6	although	although	IN
cord-263699-gosqpg3k	272	7	HPIV3	HPIV3	NNP
cord-263699-gosqpg3k	272	8	and	and	CC
cord-263699-gosqpg3k	272	9	LCMV	LCMV	NNP
cord-263699-gosqpg3k	272	10	were	be	VBD
cord-263699-gosqpg3k	272	11	shown	show	VBN
cord-263699-gosqpg3k	272	12	to	to	TO
cord-263699-gosqpg3k	272	13	depend	depend	VB
cord-263699-gosqpg3k	272	14	on	on	IN
cord-263699-gosqpg3k	272	15	GBF1	GBF1	NNP
cord-263699-gosqpg3k	272	16	,	,	,
cord-263699-gosqpg3k	272	17	the	the	DT
cord-263699-gosqpg3k	272	18	finding	finding	NN
cord-263699-gosqpg3k	272	19	that	that	IN
cord-263699-gosqpg3k	272	20	Arf1	Arf1	NNP
cord-263699-gosqpg3k	272	21	depletion	depletion	NN
cord-263699-gosqpg3k	272	22	reduces	reduce	VBZ
cord-263699-gosqpg3k	272	23	the	the	DT
cord-263699-gosqpg3k	272	24	LCMV	LCMV	NNP
cord-263699-gosqpg3k	272	25	protein	protein	NN
cord-263699-gosqpg3k	272	26	expression	expression	NN
cord-263699-gosqpg3k	272	27	,	,	,
cord-263699-gosqpg3k	272	28	but	but	CC
cord-263699-gosqpg3k	272	29	does	do	VBZ
cord-263699-gosqpg3k	272	30	not	not	RB
cord-263699-gosqpg3k	272	31	affect	affect	VB
cord-263699-gosqpg3k	272	32	that	that	DT
cord-263699-gosqpg3k	272	33	of	of	IN
cord-263699-gosqpg3k	272	34	HPIV3	hpiv3	NN
cord-263699-gosqpg3k	272	35	,	,	,
cord-263699-gosqpg3k	272	36	suggests	suggest	VBZ
cord-263699-gosqpg3k	272	37	that	that	IN
cord-263699-gosqpg3k	272	38	the	the	DT
cord-263699-gosqpg3k	272	39	role	role	NN
cord-263699-gosqpg3k	272	40	of	of	IN
cord-263699-gosqpg3k	272	41	GBF1	GBF1	NNP
cord-263699-gosqpg3k	272	42	in	in	IN
cord-263699-gosqpg3k	272	43	LCMV	LCMV	NNP
cord-263699-gosqpg3k	272	44	could	could	MD
cord-263699-gosqpg3k	272	45	be	be	VB
cord-263699-gosqpg3k	272	46	related	relate	VBN
cord-263699-gosqpg3k	272	47	to	to	IN
cord-263699-gosqpg3k	272	48	the	the	DT
cord-263699-gosqpg3k	272	49	COPI	COPI	NNP
cord-263699-gosqpg3k	272	50	transport	transport	NN
cord-263699-gosqpg3k	272	51	,	,	,
cord-263699-gosqpg3k	272	52	whereas	whereas	IN
cord-263699-gosqpg3k	272	53	for	for	IN
cord-263699-gosqpg3k	272	54	HPIV3	HPIV3	NNP
cord-263699-gosqpg3k	272	55	GBF1	GBF1	NNP
cord-263699-gosqpg3k	272	56	might	may	MD
cord-263699-gosqpg3k	272	57	play	play	VB
cord-263699-gosqpg3k	272	58	an	an	DT
cord-263699-gosqpg3k	272	59	alternative	alternative	JJ
cord-263699-gosqpg3k	272	60	function	function	NN
cord-263699-gosqpg3k	272	61	independent	independent	JJ
cord-263699-gosqpg3k	272	62	of	of	IN
cord-263699-gosqpg3k	272	63	vesicle	vesicle	NN
cord-263699-gosqpg3k	272	64	transport	transport	NN
cord-263699-gosqpg3k	272	65	,	,	,
cord-263699-gosqpg3k	272	66	although	although	IN
cord-263699-gosqpg3k	272	67	the	the	DT
cord-263699-gosqpg3k	272	68	possibility	possibility	NN
cord-263699-gosqpg3k	272	69	that	that	IN
cord-263699-gosqpg3k	272	70	HPIV3	HPIV3	NNP
cord-263699-gosqpg3k	272	71	could	could	MD
cord-263699-gosqpg3k	272	72	depend	depend	VB
cord-263699-gosqpg3k	272	73	on	on	IN
cord-263699-gosqpg3k	272	74	other	other	JJ
cord-263699-gosqpg3k	272	75	Arfs	Arfs	NNP
cord-263699-gosqpg3k	272	76	can	can	MD
cord-263699-gosqpg3k	272	77	not	not	RB
cord-263699-gosqpg3k	272	78	be	be	VB
cord-263699-gosqpg3k	272	79	ruled	rule	VBN
cord-263699-gosqpg3k	272	80	out	out	RP
cord-263699-gosqpg3k	272	81	.	.	.
cord-263699-gosqpg3k	273	1	Rotaviruses	Rotaviruses	NNP
cord-263699-gosqpg3k	273	2	are	be	VBP
cord-263699-gosqpg3k	273	3	non	non	JJ
cord-263699-gosqpg3k	273	4	-	-	JJ
cord-263699-gosqpg3k	273	5	enveloped	enveloped	JJ
cord-263699-gosqpg3k	273	6	viruses	virus	NNS
cord-263699-gosqpg3k	273	7	formed	form	VBN
cord-263699-gosqpg3k	273	8	by	by	IN
cord-263699-gosqpg3k	273	9	three	three	CD
cord-263699-gosqpg3k	273	10	concentric	concentric	JJ
cord-263699-gosqpg3k	273	11	layers	layer	NNS
cord-263699-gosqpg3k	273	12	of	of	IN
cord-263699-gosqpg3k	273	13	proteins	protein	NNS
cord-263699-gosqpg3k	273	14	that	that	WDT
cord-263699-gosqpg3k	273	15	surround	surround	VBP
cord-263699-gosqpg3k	273	16	a	a	DT
cord-263699-gosqpg3k	273	17	genome	genome	NN
cord-263699-gosqpg3k	273	18	composed	compose	VBN
cord-263699-gosqpg3k	273	19	of	of	IN
cord-263699-gosqpg3k	273	20	11	11	CD
cord-263699-gosqpg3k	273	21	segments	segment	NNS
cord-263699-gosqpg3k	273	22	of	of	IN
cord-263699-gosqpg3k	273	23	double	double	RB
cord-263699-gosqpg3k	273	24	-	-	HYPH
cord-263699-gosqpg3k	273	25	stranded	strand	VBN
cord-263699-gosqpg3k	273	26	RNA	RNA	NNP
cord-263699-gosqpg3k	273	27	(	(	-LRB-
cord-263699-gosqpg3k	273	28	dsRNA	dsrna	NN
cord-263699-gosqpg3k	273	29	)	)	-RRB-
cord-263699-gosqpg3k	274	1	that	that	DT
cord-263699-gosqpg3k	274	2	code	code	NN
cord-263699-gosqpg3k	274	3	for	for	IN
cord-263699-gosqpg3k	274	4	six	six	CD
cord-263699-gosqpg3k	274	5	nonstructural	nonstructural	JJ
cord-263699-gosqpg3k	274	6	(	(	-LRB-
cord-263699-gosqpg3k	274	7	NSP1	NSP1	NNP
cord-263699-gosqpg3k	274	8	-	-	HYPH
cord-263699-gosqpg3k	274	9	6	6	CD
cord-263699-gosqpg3k	274	10	)	)	-RRB-
cord-263699-gosqpg3k	274	11	and	and	CC
cord-263699-gosqpg3k	274	12	six	six	CD
cord-263699-gosqpg3k	274	13	structural	structural	JJ
cord-263699-gosqpg3k	274	14	(	(	-LRB-
cord-263699-gosqpg3k	274	15	VP1	VP1	NNP
cord-263699-gosqpg3k	274	16	-	-	HYPH
cord-263699-gosqpg3k	274	17	4	4	CD
cord-263699-gosqpg3k	274	18	,	,	,
cord-263699-gosqpg3k	274	19	VP6	VP6	NNS
cord-263699-gosqpg3k	274	20	,	,	,
cord-263699-gosqpg3k	274	21	and	and	CC
cord-263699-gosqpg3k	274	22	VP7	vp7	NN
cord-263699-gosqpg3k	274	23	)	)	-RRB-
cord-263699-gosqpg3k	274	24	proteins	protein	NNS
cord-263699-gosqpg3k	274	25	.	.	.
cord-263699-gosqpg3k	275	1	The	the	DT
cord-263699-gosqpg3k	275	2	inner	inner	JJ
cord-263699-gosqpg3k	275	3	core	core	NN
cord-263699-gosqpg3k	275	4	of	of	IN
cord-263699-gosqpg3k	275	5	rotavirus	rotavirus	NN
cord-263699-gosqpg3k	275	6	is	be	VBZ
cord-263699-gosqpg3k	275	7	composed	compose	VBN
cord-263699-gosqpg3k	275	8	by	by	IN
cord-263699-gosqpg3k	275	9	the	the	DT
cord-263699-gosqpg3k	275	10	protein	protein	NN
cord-263699-gosqpg3k	275	11	VP2	vp2	NN
cord-263699-gosqpg3k	275	12	,	,	,
cord-263699-gosqpg3k	275	13	which	which	WDT
cord-263699-gosqpg3k	275	14	encloses	enclose	VBZ
cord-263699-gosqpg3k	275	15	the	the	DT
cord-263699-gosqpg3k	275	16	replication	replication	NN
cord-263699-gosqpg3k	275	17	machinery	machinery	NN
cord-263699-gosqpg3k	275	18	formed	form	VBN
cord-263699-gosqpg3k	275	19	by	by	IN
cord-263699-gosqpg3k	275	20	the	the	DT
cord-263699-gosqpg3k	275	21	dsRNA	dsrna	NN
cord-263699-gosqpg3k	275	22	segments	segment	NNS
cord-263699-gosqpg3k	275	23	,	,	,
cord-263699-gosqpg3k	275	24	the	the	DT
cord-263699-gosqpg3k	275	25	RdRp	RdRp	NNP
cord-263699-gosqpg3k	275	26	VP1	VP1	NNP
cord-263699-gosqpg3k	275	27	,	,	,
cord-263699-gosqpg3k	275	28	and	and	CC
cord-263699-gosqpg3k	275	29	the	the	DT
cord-263699-gosqpg3k	275	30	protein	protein	NN
cord-263699-gosqpg3k	275	31	VP3	vp3	NN
cord-263699-gosqpg3k	275	32	.	.	.
cord-263699-gosqpg3k	276	1	The	the	DT
cord-263699-gosqpg3k	276	2	intermediate	intermediate	JJ
cord-263699-gosqpg3k	276	3	layer	layer	NN
cord-263699-gosqpg3k	276	4	,	,	,
cord-263699-gosqpg3k	276	5	formed	form	VBN
cord-263699-gosqpg3k	276	6	by	by	IN
cord-263699-gosqpg3k	276	7	VP6	VP6	NNS
cord-263699-gosqpg3k	276	8	,	,	,
cord-263699-gosqpg3k	276	9	surrounds	surround	VBZ
cord-263699-gosqpg3k	276	10	the	the	DT
cord-263699-gosqpg3k	276	11	viral	viral	JJ
cord-263699-gosqpg3k	276	12	cores	core	NNS
cord-263699-gosqpg3k	276	13	to	to	TO
cord-263699-gosqpg3k	276	14	form	form	VB
cord-263699-gosqpg3k	276	15	double	double	RB
cord-263699-gosqpg3k	276	16	-	-	HYPH
cord-263699-gosqpg3k	276	17	layered	layer	VBN
cord-263699-gosqpg3k	276	18	particles	particle	NNS
cord-263699-gosqpg3k	276	19	(	(	-LRB-
cord-263699-gosqpg3k	276	20	DLPs	DLPs	NNP
cord-263699-gosqpg3k	276	21	)	)	-RRB-
cord-263699-gosqpg3k	276	22	.	.	.
cord-263699-gosqpg3k	277	1	Finally	finally	RB
cord-263699-gosqpg3k	277	2	,	,	,
cord-263699-gosqpg3k	277	3	the	the	DT
cord-263699-gosqpg3k	277	4	addition	addition	NN
cord-263699-gosqpg3k	277	5	of	of	IN
cord-263699-gosqpg3k	277	6	the	the	DT
cord-263699-gosqpg3k	277	7	glycoprotein	glycoprotein	NN
cord-263699-gosqpg3k	277	8	VP7	vp7	NN
cord-263699-gosqpg3k	277	9	and	and	CC
cord-263699-gosqpg3k	277	10	the	the	DT
cord-263699-gosqpg3k	277	11	spike	spike	NN
cord-263699-gosqpg3k	277	12	protein	protein	NN
cord-263699-gosqpg3k	277	13	VP4	vp4	RB
cord-263699-gosqpg3k	277	14	onto	onto	IN
cord-263699-gosqpg3k	277	15	the	the	DT
cord-263699-gosqpg3k	277	16	DLPs	DLPs	NNP
cord-263699-gosqpg3k	277	17	forms	form	VBZ
cord-263699-gosqpg3k	277	18	the	the	DT
cord-263699-gosqpg3k	277	19	infectious	infectious	JJ
cord-263699-gosqpg3k	277	20	triple	triple	RB
cord-263699-gosqpg3k	277	21	-	-	HYPH
cord-263699-gosqpg3k	277	22	layered	layer	VBN
cord-263699-gosqpg3k	277	23	particles	particle	NNS
cord-263699-gosqpg3k	277	24	(	(	-LRB-
cord-263699-gosqpg3k	277	25	TLPs	TLPs	NNP
cord-263699-gosqpg3k	277	26	)	)	-RRB-
cord-263699-gosqpg3k	277	27	.	.	.
cord-263699-gosqpg3k	278	1	The	the	DT
cord-263699-gosqpg3k	278	2	replication	replication	NN
cord-263699-gosqpg3k	278	3	of	of	IN
cord-263699-gosqpg3k	278	4	rotavirus	rotavirus	NN
cord-263699-gosqpg3k	278	5	occurs	occur	VBZ
cord-263699-gosqpg3k	278	6	in	in	IN
cord-263699-gosqpg3k	278	7	cytoplasmic	cytoplasmic	JJ
cord-263699-gosqpg3k	278	8	non	non	JJ
cord-263699-gosqpg3k	278	9	-	-	JJ
cord-263699-gosqpg3k	278	10	membranous	membranous	JJ
cord-263699-gosqpg3k	278	11	electron	electron	NN
cord-263699-gosqpg3k	278	12	-	-	HYPH
cord-263699-gosqpg3k	278	13	dense	dense	JJ
cord-263699-gosqpg3k	278	14	inclusions	inclusion	NNS
cord-263699-gosqpg3k	278	15	termed	term	VBD
cord-263699-gosqpg3k	278	16	viroplasms	viroplasm	NNS
cord-263699-gosqpg3k	278	17	.	.	.
cord-263699-gosqpg3k	279	1	Replication	replication	NN
cord-263699-gosqpg3k	279	2	and	and	CC
cord-263699-gosqpg3k	279	3	packaging	packaging	NN
cord-263699-gosqpg3k	279	4	of	of	IN
cord-263699-gosqpg3k	279	5	the	the	DT
cord-263699-gosqpg3k	279	6	viral	viral	JJ
cord-263699-gosqpg3k	279	7	genome	genome	NN
cord-263699-gosqpg3k	279	8	into	into	IN
cord-263699-gosqpg3k	279	9	newly	newly	RB
cord-263699-gosqpg3k	279	10	synthesized	synthesize	VBN
cord-263699-gosqpg3k	279	11	DLPs	dlp	NNS
cord-263699-gosqpg3k	279	12	take	take	VBP
cord-263699-gosqpg3k	279	13	place	place	NN
cord-263699-gosqpg3k	279	14	in	in	IN
cord-263699-gosqpg3k	279	15	these	these	DT
cord-263699-gosqpg3k	279	16	inclusions	inclusion	NNS
cord-263699-gosqpg3k	279	17	.	.	.
cord-263699-gosqpg3k	280	1	The	the	DT
cord-263699-gosqpg3k	280	2	novel	novel	JJ
cord-263699-gosqpg3k	280	3	DLPs	dlps	NN
cord-263699-gosqpg3k	280	4	then	then	RB
cord-263699-gosqpg3k	280	5	bud	bud	VB
cord-263699-gosqpg3k	280	6	into	into	IN
cord-263699-gosqpg3k	280	7	the	the	DT
cord-263699-gosqpg3k	280	8	lumen	lumen	NN
cord-263699-gosqpg3k	280	9	of	of	IN
cord-263699-gosqpg3k	280	10	ER	ER	NNP
cord-263699-gosqpg3k	280	11	through	through	IN
cord-263699-gosqpg3k	280	12	membrane	membrane	NN
cord-263699-gosqpg3k	280	13	sites	site	NNS
cord-263699-gosqpg3k	280	14	modified	modify	VBN
cord-263699-gosqpg3k	280	15	by	by	IN
cord-263699-gosqpg3k	280	16	the	the	DT
cord-263699-gosqpg3k	280	17	presence	presence	NN
cord-263699-gosqpg3k	280	18	of	of	IN
cord-263699-gosqpg3k	280	19	NSP4	NSP4	NNP
cord-263699-gosqpg3k	280	20	and	and	CC
cord-263699-gosqpg3k	280	21	VP7	VP7	NNP
cord-263699-gosqpg3k	280	22	,	,	,
cord-263699-gosqpg3k	280	23	acquiring	acquire	VBG
cord-263699-gosqpg3k	280	24	a	a	DT
cord-263699-gosqpg3k	280	25	transitory	transitory	JJ
cord-263699-gosqpg3k	280	26	lipid	lipid	NN
cord-263699-gosqpg3k	280	27	envelope	envelope	NN
cord-263699-gosqpg3k	280	28	bearing	bear	VBG
cord-263699-gosqpg3k	280	29	the	the	DT
cord-263699-gosqpg3k	280	30	NSP4	NSP4	NNP
cord-263699-gosqpg3k	280	31	,	,	,
cord-263699-gosqpg3k	280	32	VP7	vp7	NN
cord-263699-gosqpg3k	280	33	,	,	,
cord-263699-gosqpg3k	280	34	and	and	CC
cord-263699-gosqpg3k	280	35	VP4	vp4	JJ
cord-263699-gosqpg3k	280	36	proteins	protein	NNS
cord-263699-gosqpg3k	280	37	.	.	.
cord-263699-gosqpg3k	281	1	As	as	IN
cord-263699-gosqpg3k	281	2	the	the	DT
cord-263699-gosqpg3k	281	3	new	new	JJ
cord-263699-gosqpg3k	281	4	DLPs	dlp	NNS
cord-263699-gosqpg3k	281	5	move	move	VBP
cord-263699-gosqpg3k	281	6	into	into	IN
cord-263699-gosqpg3k	281	7	the	the	DT
cord-263699-gosqpg3k	281	8	lumen	lumen	NN
cord-263699-gosqpg3k	281	9	of	of	IN
cord-263699-gosqpg3k	281	10	the	the	DT
cord-263699-gosqpg3k	281	11	ER	ER	NNP
cord-263699-gosqpg3k	281	12	,	,	,
cord-263699-gosqpg3k	281	13	the	the	DT
cord-263699-gosqpg3k	281	14	transient	transient	JJ
cord-263699-gosqpg3k	281	15	lipid	lipid	NN
cord-263699-gosqpg3k	281	16	envelope	envelope	NN
cord-263699-gosqpg3k	281	17	is	be	VBZ
cord-263699-gosqpg3k	281	18	removed	remove	VBN
cord-263699-gosqpg3k	281	19	by	by	IN
cord-263699-gosqpg3k	281	20	an	an	DT
cord-263699-gosqpg3k	281	21	unknown	unknown	JJ
cord-263699-gosqpg3k	281	22	process	process	NN
cord-263699-gosqpg3k	281	23	in	in	IN
cord-263699-gosqpg3k	281	24	which	which	WDT
cord-263699-gosqpg3k	281	25	NSP4	NSP4	NNP
cord-263699-gosqpg3k	281	26	is	be	VBZ
cord-263699-gosqpg3k	281	27	eliminated	eliminate	VBN
cord-263699-gosqpg3k	281	28	while	while	IN
cord-263699-gosqpg3k	281	29	VP4	VP4	NNP
cord-263699-gosqpg3k	281	30	and	and	CC
cord-263699-gosqpg3k	281	31	VP7	vp7	NN
cord-263699-gosqpg3k	281	32	are	be	VBP
cord-263699-gosqpg3k	281	33	assembled	assemble	VBN
cord-263699-gosqpg3k	281	34	to	to	TO
cord-263699-gosqpg3k	281	35	produce	produce	VB
cord-263699-gosqpg3k	281	36	the	the	DT
cord-263699-gosqpg3k	281	37	final	final	JJ
cord-263699-gosqpg3k	281	38	infectious	infectious	JJ
cord-263699-gosqpg3k	281	39	TLPs	tlp	NNS
cord-263699-gosqpg3k	281	40	[	[	-LRB-
cord-263699-gosqpg3k	281	41	139	139	CD
cord-263699-gosqpg3k	281	42	]	]	-RRB-
cord-263699-gosqpg3k	281	43	.	.	.
cord-263699-gosqpg3k	282	1	Although	although	IN
cord-263699-gosqpg3k	282	2	many	many	JJ
cord-263699-gosqpg3k	282	3	of	of	IN
cord-263699-gosqpg3k	282	4	the	the	DT
cord-263699-gosqpg3k	282	5	steps	step	NNS
cord-263699-gosqpg3k	282	6	of	of	IN
cord-263699-gosqpg3k	282	7	rotavirus	rotavirus	NN
cord-263699-gosqpg3k	282	8	replication	replication	NN
cord-263699-gosqpg3k	282	9	have	have	VBP
cord-263699-gosqpg3k	282	10	been	be	VBN
cord-263699-gosqpg3k	282	11	elucidated	elucidate	VBN
cord-263699-gosqpg3k	282	12	in	in	IN
cord-263699-gosqpg3k	282	13	recent	recent	JJ
cord-263699-gosqpg3k	282	14	years	year	NNS
cord-263699-gosqpg3k	282	15	,	,	,
cord-263699-gosqpg3k	282	16	the	the	DT
cord-263699-gosqpg3k	282	17	precise	precise	JJ
cord-263699-gosqpg3k	282	18	mechanism	mechanism	NN
cord-263699-gosqpg3k	282	19	of	of	IN
cord-263699-gosqpg3k	282	20	the	the	DT
cord-263699-gosqpg3k	282	21	final	final	JJ
cord-263699-gosqpg3k	282	22	events	event	NNS
cord-263699-gosqpg3k	282	23	of	of	IN
cord-263699-gosqpg3k	282	24	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	282	25	assembly	assembly	NN
cord-263699-gosqpg3k	282	26	is	be	VBZ
cord-263699-gosqpg3k	282	27	not	not	RB
cord-263699-gosqpg3k	282	28	well	well	RB
cord-263699-gosqpg3k	282	29	understood	understand	VBN
cord-263699-gosqpg3k	282	30	.	.	.
cord-263699-gosqpg3k	283	1	It	-PRON-	PRP
cord-263699-gosqpg3k	283	2	is	be	VBZ
cord-263699-gosqpg3k	283	3	known	know	VBN
cord-263699-gosqpg3k	283	4	that	that	IN
cord-263699-gosqpg3k	283	5	NSP4	NSP4	NNP
cord-263699-gosqpg3k	283	6	(	(	-LRB-
cord-263699-gosqpg3k	283	7	a	a	DT
cord-263699-gosqpg3k	283	8	transmembrane	transmembrane	NN
cord-263699-gosqpg3k	283	9	ER	er	NN
cord-263699-gosqpg3k	283	10	glycoprotein	glycoprotein	NN
cord-263699-gosqpg3k	283	11	)	)	-RRB-
cord-263699-gosqpg3k	283	12	plays	play	VBZ
cord-263699-gosqpg3k	283	13	a	a	DT
cord-263699-gosqpg3k	283	14	crucial	crucial	JJ
cord-263699-gosqpg3k	283	15	role	role	NN
cord-263699-gosqpg3k	283	16	in	in	IN
cord-263699-gosqpg3k	283	17	the	the	DT
cord-263699-gosqpg3k	283	18	last	last	JJ
cord-263699-gosqpg3k	283	19	steps	step	NNS
cord-263699-gosqpg3k	283	20	of	of	IN
cord-263699-gosqpg3k	283	21	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	283	22	assembly	assembly	NN
cord-263699-gosqpg3k	283	23	.	.	.
cord-263699-gosqpg3k	284	1	The	the	DT
cord-263699-gosqpg3k	284	2	interaction	interaction	NN
cord-263699-gosqpg3k	284	3	of	of	IN
cord-263699-gosqpg3k	284	4	NSP4	NSP4	NNP
cord-263699-gosqpg3k	284	5	with	with	IN
cord-263699-gosqpg3k	284	6	VP4	VP4	NNP
cord-263699-gosqpg3k	284	7	and	and	CC
cord-263699-gosqpg3k	284	8	VP7	VP7	NNP
cord-263699-gosqpg3k	284	9	[	[	-LRB-
cord-263699-gosqpg3k	284	10	140	140	CD
cord-263699-gosqpg3k	284	11	]	]	-RRB-
cord-263699-gosqpg3k	284	12	,	,	,
cord-263699-gosqpg3k	284	13	together	together	RB
cord-263699-gosqpg3k	284	14	with	with	IN
cord-263699-gosqpg3k	284	15	the	the	DT
cord-263699-gosqpg3k	284	16	binding	binding	NN
cord-263699-gosqpg3k	284	17	of	of	IN
cord-263699-gosqpg3k	284	18	NSP4	NSP4	NNP
cord-263699-gosqpg3k	284	19	to	to	IN
cord-263699-gosqpg3k	284	20	the	the	DT
cord-263699-gosqpg3k	284	21	VP6	vp6	NN
cord-263699-gosqpg3k	284	22	protein	protein	NN
cord-263699-gosqpg3k	284	23	on	on	IN
cord-263699-gosqpg3k	284	24	the	the	DT
cord-263699-gosqpg3k	284	25	surface	surface	NN
cord-263699-gosqpg3k	284	26	of	of	IN
cord-263699-gosqpg3k	284	27	DLPs	dlps	NN
cord-263699-gosqpg3k	284	28	,	,	,
cord-263699-gosqpg3k	284	29	has	have	VBZ
cord-263699-gosqpg3k	284	30	been	be	VBN
cord-263699-gosqpg3k	284	31	proposed	propose	VBN
cord-263699-gosqpg3k	284	32	to	to	TO
cord-263699-gosqpg3k	284	33	drive	drive	VB
cord-263699-gosqpg3k	284	34	the	the	DT
cord-263699-gosqpg3k	284	35	incorporation	incorporation	NN
cord-263699-gosqpg3k	284	36	of	of	IN
cord-263699-gosqpg3k	284	37	the	the	DT
cord-263699-gosqpg3k	284	38	outer	outer	JJ
cord-263699-gosqpg3k	284	39	layer	layer	NN
cord-263699-gosqpg3k	284	40	proteins	protein	NNS
cord-263699-gosqpg3k	284	41	to	to	TO
cord-263699-gosqpg3k	284	42	form	form	VB
cord-263699-gosqpg3k	284	43	the	the	DT
cord-263699-gosqpg3k	284	44	final	final	JJ
cord-263699-gosqpg3k	284	45	TLPs	tlp	NNS
cord-263699-gosqpg3k	284	46	.	.	.
cord-263699-gosqpg3k	285	1	However	however	RB
cord-263699-gosqpg3k	285	2	,	,	,
cord-263699-gosqpg3k	285	3	whether	whether	IN
cord-263699-gosqpg3k	285	4	specific	specific	JJ
cord-263699-gosqpg3k	285	5	cellular	cellular	JJ
cord-263699-gosqpg3k	285	6	pathways	pathway	NNS
cord-263699-gosqpg3k	285	7	or	or	CC
cord-263699-gosqpg3k	285	8	cell	cell	NN
cord-263699-gosqpg3k	285	9	proteins	protein	NNS
cord-263699-gosqpg3k	285	10	are	be	VBP
cord-263699-gosqpg3k	285	11	involved	involve	VBN
cord-263699-gosqpg3k	285	12	in	in	IN
cord-263699-gosqpg3k	285	13	the	the	DT
cord-263699-gosqpg3k	285	14	assembly	assembly	NN
cord-263699-gosqpg3k	285	15	process	process	NN
cord-263699-gosqpg3k	285	16	remains	remain	VBZ
cord-263699-gosqpg3k	285	17	unknown	unknown	JJ
cord-263699-gosqpg3k	285	18	.	.	.
cord-263699-gosqpg3k	286	1	In	in	IN
cord-263699-gosqpg3k	286	2	recent	recent	JJ
cord-263699-gosqpg3k	286	3	years	year	NNS
cord-263699-gosqpg3k	286	4	,	,	,
cord-263699-gosqpg3k	286	5	the	the	DT
cord-263699-gosqpg3k	286	6	use	use	NN
cord-263699-gosqpg3k	286	7	of	of	IN
cord-263699-gosqpg3k	286	8	genome	genome	NN
cord-263699-gosqpg3k	286	9	-	-	HYPH
cord-263699-gosqpg3k	286	10	wide	wide	JJ
cord-263699-gosqpg3k	286	11	RNAi	RNAi	NNS
cord-263699-gosqpg3k	286	12	screens	screen	NNS
cord-263699-gosqpg3k	286	13	has	have	VBZ
cord-263699-gosqpg3k	286	14	shown	show	VBN
cord-263699-gosqpg3k	286	15	that	that	IN
cord-263699-gosqpg3k	286	16	the	the	DT
cord-263699-gosqpg3k	286	17	vesicle	vesicle	NN
cord-263699-gosqpg3k	286	18	transport	transport	NN
cord-263699-gosqpg3k	286	19	mediated	mediate	VBN
cord-263699-gosqpg3k	286	20	by	by	IN
cord-263699-gosqpg3k	286	21	the	the	DT
cord-263699-gosqpg3k	286	22	COPI	COPI	NNP
cord-263699-gosqpg3k	286	23	/	/	SYM
cord-263699-gosqpg3k	286	24	Arf1	Arf1	NNP
cord-263699-gosqpg3k	286	25	machinery	machinery	NN
cord-263699-gosqpg3k	286	26	is	be	VBZ
cord-263699-gosqpg3k	286	27	relevant	relevant	JJ
cord-263699-gosqpg3k	286	28	for	for	IN
cord-263699-gosqpg3k	286	29	virus	virus	NN
cord-263699-gosqpg3k	286	30	replication	replication	NN
cord-263699-gosqpg3k	286	31	,	,	,
cord-263699-gosqpg3k	286	32	since	since	IN
cord-263699-gosqpg3k	286	33	knocking	knock	VBG
cord-263699-gosqpg3k	286	34	down	down	RP
cord-263699-gosqpg3k	286	35	the	the	DT
cord-263699-gosqpg3k	286	36	expression	expression	NN
cord-263699-gosqpg3k	286	37	of	of	IN
cord-263699-gosqpg3k	286	38	some	some	DT
cord-263699-gosqpg3k	286	39	of	of	IN
cord-263699-gosqpg3k	286	40	the	the	DT
cord-263699-gosqpg3k	286	41	proteins	protein	NNS
cord-263699-gosqpg3k	286	42	that	that	WDT
cord-263699-gosqpg3k	286	43	integrate	integrate	VBP
cord-263699-gosqpg3k	286	44	such	such	JJ
cord-263699-gosqpg3k	286	45	machinery	machinery	NN
cord-263699-gosqpg3k	286	46	significantly	significantly	RB
cord-263699-gosqpg3k	286	47	impairs	impair	VBZ
cord-263699-gosqpg3k	286	48	the	the	DT
cord-263699-gosqpg3k	286	49	yield	yield	NN
cord-263699-gosqpg3k	286	50	of	of	IN
cord-263699-gosqpg3k	286	51	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	286	52	progeny	progeny	NN
cord-263699-gosqpg3k	286	53	[	[	-LRB-
cord-263699-gosqpg3k	286	54	141	141	CD
cord-263699-gosqpg3k	286	55	,	,	,
cord-263699-gosqpg3k	286	56	142	142	CD
cord-263699-gosqpg3k	286	57	]	]	-RRB-
cord-263699-gosqpg3k	286	58	;	;	:
cord-263699-gosqpg3k	286	59	similar	similar	JJ
cord-263699-gosqpg3k	286	60	results	result	NNS
cord-263699-gosqpg3k	286	61	are	be	VBP
cord-263699-gosqpg3k	286	62	obtained	obtain	VBN
cord-263699-gosqpg3k	286	63	when	when	WRB
cord-263699-gosqpg3k	286	64	the	the	DT
cord-263699-gosqpg3k	286	65	vesicle	vesicle	NN
cord-263699-gosqpg3k	286	66	transport	transport	NN
cord-263699-gosqpg3k	286	67	is	be	VBZ
cord-263699-gosqpg3k	286	68	inhibited	inhibit	VBN
cord-263699-gosqpg3k	286	69	by	by	IN
cord-263699-gosqpg3k	286	70	BFA	BFA	NNP
cord-263699-gosqpg3k	286	71	treatment	treatment	NN
cord-263699-gosqpg3k	286	72	of	of	IN
cord-263699-gosqpg3k	286	73	rotavirus	rotavirus	NN
cord-263699-gosqpg3k	286	74	-	-	HYPH
cord-263699-gosqpg3k	286	75	infected	infect	VBN
cord-263699-gosqpg3k	286	76	cells	cell	NNS
cord-263699-gosqpg3k	286	77	[	[	-LRB-
cord-263699-gosqpg3k	286	78	76	76	CD
cord-263699-gosqpg3k	286	79	,	,	,
cord-263699-gosqpg3k	286	80	143	143	CD
cord-263699-gosqpg3k	286	81	]	]	-RRB-
cord-263699-gosqpg3k	286	82	.	.	.
cord-263699-gosqpg3k	287	1	This	this	DT
cord-263699-gosqpg3k	287	2	inhibition	inhibition	NN
cord-263699-gosqpg3k	287	3	is	be	VBZ
cord-263699-gosqpg3k	287	4	related	relate	VBN
cord-263699-gosqpg3k	287	5	to	to	IN
cord-263699-gosqpg3k	287	6	the	the	DT
cord-263699-gosqpg3k	287	7	activity	activity	NN
cord-263699-gosqpg3k	287	8	of	of	IN
cord-263699-gosqpg3k	287	9	GBF1	GBF1	NNP
cord-263699-gosqpg3k	287	10	,	,	,
cord-263699-gosqpg3k	287	11	since	since	IN
cord-263699-gosqpg3k	287	12	interfering	interfere	VBG
cord-263699-gosqpg3k	287	13	specifically	specifically	RB
cord-263699-gosqpg3k	287	14	with	with	IN
cord-263699-gosqpg3k	287	15	this	this	DT
cord-263699-gosqpg3k	287	16	factor	factor	NN
cord-263699-gosqpg3k	287	17	by	by	IN
cord-263699-gosqpg3k	287	18	GCA	GCA	NNP
cord-263699-gosqpg3k	287	19	,	,	,
cord-263699-gosqpg3k	287	20	or	or	CC
cord-263699-gosqpg3k	287	21	depletion	depletion	NN
cord-263699-gosqpg3k	287	22	of	of	IN
cord-263699-gosqpg3k	287	23	this	this	DT
cord-263699-gosqpg3k	287	24	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	287	25	exchange	exchange	NN
cord-263699-gosqpg3k	287	26	factor	factor	NN
cord-263699-gosqpg3k	287	27	by	by	IN
cord-263699-gosqpg3k	287	28	RNAi	RNAi	NNP
cord-263699-gosqpg3k	287	29	,	,	,
cord-263699-gosqpg3k	287	30	significantly	significantly	RB
cord-263699-gosqpg3k	287	31	reduced	reduce	VBD
cord-263699-gosqpg3k	287	32	the	the	DT
cord-263699-gosqpg3k	287	33	production	production	NN
cord-263699-gosqpg3k	287	34	of	of	IN
cord-263699-gosqpg3k	287	35	new	new	JJ
cord-263699-gosqpg3k	287	36	viral	viral	JJ
cord-263699-gosqpg3k	287	37	infectious	infectious	JJ
cord-263699-gosqpg3k	287	38	particles	particle	NNS
cord-263699-gosqpg3k	287	39	[	[	-LRB-
cord-263699-gosqpg3k	287	40	76	76	CD
cord-263699-gosqpg3k	287	41	]	]	-RRB-
cord-263699-gosqpg3k	287	42	.	.	.
cord-263699-gosqpg3k	288	1	In	in	IN
cord-263699-gosqpg3k	288	2	addition	addition	NN
cord-263699-gosqpg3k	288	3	,	,	,
cord-263699-gosqpg3k	288	4	the	the	DT
cord-263699-gosqpg3k	288	5	block	block	NN
cord-263699-gosqpg3k	288	6	in	in	IN
cord-263699-gosqpg3k	288	7	the	the	DT
cord-263699-gosqpg3k	288	8	production	production	NN
cord-263699-gosqpg3k	288	9	of	of	IN
cord-263699-gosqpg3k	288	10	infectious	infectious	JJ
cord-263699-gosqpg3k	288	11	virus	virus	NN
cord-263699-gosqpg3k	288	12	was	be	VBD
cord-263699-gosqpg3k	288	13	associated	associate	VBN
cord-263699-gosqpg3k	288	14	with	with	IN
cord-263699-gosqpg3k	288	15	the	the	DT
cord-263699-gosqpg3k	288	16	assembly	assembly	NN
cord-263699-gosqpg3k	288	17	of	of	IN
cord-263699-gosqpg3k	288	18	the	the	DT
cord-263699-gosqpg3k	288	19	virus	virus	NN
cord-263699-gosqpg3k	288	20	surface	surface	NN
cord-263699-gosqpg3k	288	21	proteins	protein	NNS
cord-263699-gosqpg3k	288	22	VP7	vp7	VBP
cord-263699-gosqpg3k	288	23	and	and	CC
cord-263699-gosqpg3k	288	24	VP4	VP4	NNP
cord-263699-gosqpg3k	288	25	,	,	,
cord-263699-gosqpg3k	288	26	since	since	IN
cord-263699-gosqpg3k	288	27	both	both	CC
cord-263699-gosqpg3k	288	28	BFA	BFA	NNP
cord-263699-gosqpg3k	288	29	and	and	CC
cord-263699-gosqpg3k	288	30	GCA	GCA	NNP
cord-263699-gosqpg3k	288	31	block	block	VB
cord-263699-gosqpg3k	288	32	the	the	DT
cord-263699-gosqpg3k	288	33	assembly	assembly	NN
cord-263699-gosqpg3k	288	34	of	of	IN
cord-263699-gosqpg3k	288	35	the	the	DT
cord-263699-gosqpg3k	288	36	viral	viral	JJ
cord-263699-gosqpg3k	288	37	surface	surface	NN
cord-263699-gosqpg3k	288	38	proteins	protein	NNS
cord-263699-gosqpg3k	288	39	onto	onto	IN
cord-263699-gosqpg3k	288	40	DLPs	dlps	NN
cord-263699-gosqpg3k	288	41	,	,	,
cord-263699-gosqpg3k	288	42	preventing	prevent	VBG
cord-263699-gosqpg3k	288	43	the	the	DT
cord-263699-gosqpg3k	288	44	production	production	NN
cord-263699-gosqpg3k	288	45	of	of	IN
cord-263699-gosqpg3k	288	46	mature	mature	JJ
cord-263699-gosqpg3k	288	47	infectious	infectious	JJ
cord-263699-gosqpg3k	288	48	TLPs	tlp	NNS
cord-263699-gosqpg3k	288	49	[	[	-LRB-
cord-263699-gosqpg3k	288	50	76	76	CD
cord-263699-gosqpg3k	288	51	]	]	-RRB-
cord-263699-gosqpg3k	288	52	.	.	.
cord-263699-gosqpg3k	289	1	The	the	DT
cord-263699-gosqpg3k	289	2	restriction	restriction	NN
cord-263699-gosqpg3k	289	3	in	in	IN
cord-263699-gosqpg3k	289	4	the	the	DT
cord-263699-gosqpg3k	289	5	assembly	assembly	NN
cord-263699-gosqpg3k	289	6	of	of	IN
cord-263699-gosqpg3k	289	7	TLPs	TLPs	NNP
cord-263699-gosqpg3k	289	8	was	be	VBD
cord-263699-gosqpg3k	289	9	shown	show	VBN
cord-263699-gosqpg3k	289	10	to	to	TO
cord-263699-gosqpg3k	289	11	be	be	VB
cord-263699-gosqpg3k	289	12	the	the	DT
cord-263699-gosqpg3k	289	13	result	result	NN
cord-263699-gosqpg3k	289	14	of	of	IN
cord-263699-gosqpg3k	289	15	a	a	DT
cord-263699-gosqpg3k	289	16	defective	defective	JJ
cord-263699-gosqpg3k	289	17	trimerization	trimerization	NN
cord-263699-gosqpg3k	289	18	of	of	IN
cord-263699-gosqpg3k	289	19	VP7	vp7	NN
cord-263699-gosqpg3k	289	20	,	,	,
cord-263699-gosqpg3k	289	21	required	require	VBN
cord-263699-gosqpg3k	289	22	for	for	IN
cord-263699-gosqpg3k	289	23	its	-PRON-	PRP$
cord-263699-gosqpg3k	289	24	assembly	assembly	NN
cord-263699-gosqpg3k	289	25	onto	onto	IN
cord-263699-gosqpg3k	289	26	DLPs	dlp	NNS
cord-263699-gosqpg3k	289	27	,	,	,
cord-263699-gosqpg3k	289	28	rather	rather	RB
cord-263699-gosqpg3k	289	29	than	than	IN
cord-263699-gosqpg3k	289	30	a	a	DT
cord-263699-gosqpg3k	289	31	block	block	NN
cord-263699-gosqpg3k	289	32	in	in	IN
cord-263699-gosqpg3k	289	33	the	the	DT
cord-263699-gosqpg3k	289	34	budding	budding	NN
cord-263699-gosqpg3k	289	35	of	of	IN
cord-263699-gosqpg3k	289	36	DLPs	dlps	NN
cord-263699-gosqpg3k	289	37	into	into	IN
cord-263699-gosqpg3k	289	38	the	the	DT
cord-263699-gosqpg3k	289	39	ER	ER	NNP
cord-263699-gosqpg3k	289	40	lumen	lumen	NN
cord-263699-gosqpg3k	289	41	.	.	.
cord-263699-gosqpg3k	290	1	It	-PRON-	PRP
cord-263699-gosqpg3k	290	2	has	have	VBZ
cord-263699-gosqpg3k	290	3	been	be	VBN
cord-263699-gosqpg3k	290	4	shown	show	VBN
cord-263699-gosqpg3k	290	5	that	that	IN
cord-263699-gosqpg3k	290	6	the	the	DT
cord-263699-gosqpg3k	290	7	inhibition	inhibition	NN
cord-263699-gosqpg3k	290	8	of	of	IN
cord-263699-gosqpg3k	290	9	GBF1	GBF1	NNP
cord-263699-gosqpg3k	290	10	by	by	IN
cord-263699-gosqpg3k	290	11	either	either	DT
cord-263699-gosqpg3k	290	12	BFA	BFA	NNP
cord-263699-gosqpg3k	290	13	or	or	CC
cord-263699-gosqpg3k	290	14	GCA	GCA	NNP
cord-263699-gosqpg3k	290	15	,	,	,
cord-263699-gosqpg3k	290	16	or	or	CC
cord-263699-gosqpg3k	290	17	the	the	DT
cord-263699-gosqpg3k	290	18	depletion	depletion	NN
cord-263699-gosqpg3k	290	19	of	of	IN
cord-263699-gosqpg3k	290	20	this	this	DT
cord-263699-gosqpg3k	290	21	factor	factor	NN
cord-263699-gosqpg3k	290	22	by	by	IN
cord-263699-gosqpg3k	290	23	RNAi	RNAi	NNP
cord-263699-gosqpg3k	290	24	,	,	,
cord-263699-gosqpg3k	290	25	alters	alter	VBZ
cord-263699-gosqpg3k	290	26	the	the	DT
cord-263699-gosqpg3k	290	27	electrophoretic	electrophoretic	JJ
cord-263699-gosqpg3k	290	28	mobility	mobility	NN
cord-263699-gosqpg3k	290	29	of	of	IN
cord-263699-gosqpg3k	290	30	the	the	DT
cord-263699-gosqpg3k	290	31	viral	viral	JJ
cord-263699-gosqpg3k	290	32	glycoproteins	glycoprotein	NNS
cord-263699-gosqpg3k	290	33	VP7	vp7	NN
cord-263699-gosqpg3k	290	34	and	and	CC
cord-263699-gosqpg3k	290	35	NSP4	NSP4	NNP
cord-263699-gosqpg3k	290	36	[	[	-LRB-
cord-263699-gosqpg3k	290	37	76	76	CD
cord-263699-gosqpg3k	290	38	,	,	,
cord-263699-gosqpg3k	290	39	143	143	CD
cord-263699-gosqpg3k	290	40	]	]	-RRB-
cord-263699-gosqpg3k	290	41	.	.	.
cord-263699-gosqpg3k	291	1	Although	although	IN
cord-263699-gosqpg3k	291	2	the	the	DT
cord-263699-gosqpg3k	291	3	altered	altered	JJ
cord-263699-gosqpg3k	291	4	posttranslational	posttranslational	JJ
cord-263699-gosqpg3k	291	5	modification	modification	NN
cord-263699-gosqpg3k	291	6	of	of	IN
cord-263699-gosqpg3k	291	7	VP7	vp7	NN
cord-263699-gosqpg3k	291	8	was	be	VBD
cord-263699-gosqpg3k	291	9	initially	initially	RB
cord-263699-gosqpg3k	291	10	considered	consider	VBN
cord-263699-gosqpg3k	291	11	to	to	TO
cord-263699-gosqpg3k	291	12	explain	explain	VB
cord-263699-gosqpg3k	291	13	its	-PRON-	PRP$
cord-263699-gosqpg3k	291	14	lack	lack	NN
cord-263699-gosqpg3k	291	15	of	of	IN
cord-263699-gosqpg3k	291	16	trimerization	trimerization	NN
cord-263699-gosqpg3k	291	17	,	,	,
cord-263699-gosqpg3k	291	18	increasing	increase	VBG
cord-263699-gosqpg3k	291	19	evidence	evidence	NN
cord-263699-gosqpg3k	291	20	has	have	VBZ
cord-263699-gosqpg3k	291	21	pointed	point	VBN
cord-263699-gosqpg3k	291	22	out	out	RP
cord-263699-gosqpg3k	291	23	that	that	IN
cord-263699-gosqpg3k	291	24	the	the	DT
cord-263699-gosqpg3k	291	25	alteration	alteration	NN
cord-263699-gosqpg3k	291	26	of	of	IN
cord-263699-gosqpg3k	291	27	NSP4	NSP4	NNP
cord-263699-gosqpg3k	291	28	is	be	VBZ
cord-263699-gosqpg3k	291	29	rather	rather	RB
cord-263699-gosqpg3k	291	30	responsible	responsible	JJ
cord-263699-gosqpg3k	291	31	,	,	,
cord-263699-gosqpg3k	291	32	since	since	IN
cord-263699-gosqpg3k	291	33	depletion	depletion	NN
cord-263699-gosqpg3k	291	34	of	of	IN
cord-263699-gosqpg3k	291	35	this	this	DT
cord-263699-gosqpg3k	291	36	protein	protein	NN
cord-263699-gosqpg3k	291	37	or	or	CC
cord-263699-gosqpg3k	291	38	alteration	alteration	NN
cord-263699-gosqpg3k	291	39	of	of	IN
cord-263699-gosqpg3k	291	40	its	-PRON-	PRP$
cord-263699-gosqpg3k	291	41	posttranslational	posttranslational	JJ
cord-263699-gosqpg3k	291	42	processing	processing	NN
cord-263699-gosqpg3k	291	43	with	with	IN
cord-263699-gosqpg3k	291	44	tunicamycin	tunicamycin	NNS
cord-263699-gosqpg3k	291	45	,	,	,
cord-263699-gosqpg3k	291	46	an	an	DT
cord-263699-gosqpg3k	291	47	inhibitor	inhibitor	NN
cord-263699-gosqpg3k	291	48	of	of	IN
cord-263699-gosqpg3k	291	49	N	n	NN
cord-263699-gosqpg3k	291	50	-	-	HYPH
cord-263699-gosqpg3k	291	51	glycosylation	glycosylation	NN
cord-263699-gosqpg3k	291	52	,	,	,
cord-263699-gosqpg3k	291	53	affects	affect	VBZ
cord-263699-gosqpg3k	291	54	the	the	DT
cord-263699-gosqpg3k	291	55	trimerization	trimerization	NN
cord-263699-gosqpg3k	291	56	of	of	IN
cord-263699-gosqpg3k	291	57	VP7	vp7	NN
cord-263699-gosqpg3k	291	58	and	and	CC
cord-263699-gosqpg3k	291	59	restricts	restrict	VBZ
cord-263699-gosqpg3k	291	60	the	the	DT
cord-263699-gosqpg3k	291	61	maturation	maturation	NN
cord-263699-gosqpg3k	291	62	of	of	IN
cord-263699-gosqpg3k	291	63	the	the	DT
cord-263699-gosqpg3k	291	64	transient	transient	JJ
cord-263699-gosqpg3k	291	65	enveloped	envelop	VBD
cord-263699-gosqpg3k	291	66	viral	viral	JJ
cord-263699-gosqpg3k	291	67	particles	particle	NNS
cord-263699-gosqpg3k	291	68	to	to	IN
cord-263699-gosqpg3k	291	69	TLPs	tlp	NNS
cord-263699-gosqpg3k	291	70	.	.	.
cord-263699-gosqpg3k	292	1	[	[	-LRB-
cord-263699-gosqpg3k	292	2	76	76	CD
cord-263699-gosqpg3k	292	3	,	,	,
cord-263699-gosqpg3k	292	4	144	144	CD
cord-263699-gosqpg3k	292	5	,	,	,
cord-263699-gosqpg3k	292	6	145	145	CD
cord-263699-gosqpg3k	292	7	]	]	-RRB-
cord-263699-gosqpg3k	292	8	.	.	.
cord-263699-gosqpg3k	293	1	In	in	IN
cord-263699-gosqpg3k	293	2	support	support	NN
cord-263699-gosqpg3k	293	3	of	of	IN
cord-263699-gosqpg3k	293	4	this	this	DT
cord-263699-gosqpg3k	293	5	observation	observation	NN
cord-263699-gosqpg3k	293	6	,	,	,
cord-263699-gosqpg3k	293	7	it	-PRON-	PRP
cord-263699-gosqpg3k	293	8	was	be	VBD
cord-263699-gosqpg3k	293	9	recently	recently	RB
cord-263699-gosqpg3k	293	10	demonstrated	demonstrate	VBN
cord-263699-gosqpg3k	293	11	that	that	IN
cord-263699-gosqpg3k	293	12	a	a	DT
cord-263699-gosqpg3k	293	13	recombinant	recombinant	JJ
cord-263699-gosqpg3k	293	14	VP7	vp7	NN
cord-263699-gosqpg3k	293	15	protein	protein	NN
cord-263699-gosqpg3k	293	16	overexpressed	overexpresse	VBN
cord-263699-gosqpg3k	293	17	in	in	IN
cord-263699-gosqpg3k	293	18	transfected	transfecte	VBN
cord-263699-gosqpg3k	293	19	cells	cell	NNS
cord-263699-gosqpg3k	293	20	formed	form	VBD
cord-263699-gosqpg3k	293	21	trimers	trimer	NNS
cord-263699-gosqpg3k	293	22	only	only	RB
cord-263699-gosqpg3k	293	23	when	when	WRB
cord-263699-gosqpg3k	293	24	co	co	NN
cord-263699-gosqpg3k	293	25	-	-	VBD
cord-263699-gosqpg3k	293	26	expressed	express	VBN
cord-263699-gosqpg3k	293	27	with	with	IN
cord-263699-gosqpg3k	293	28	NSP4	NSP4	NNP
cord-263699-gosqpg3k	293	29	[	[	-LRB-
cord-263699-gosqpg3k	293	30	76	76	CD
cord-263699-gosqpg3k	293	31	]	]	-RRB-
cord-263699-gosqpg3k	293	32	.	.	.
cord-263699-gosqpg3k	294	1	Therefore	therefore	RB
cord-263699-gosqpg3k	294	2	,	,	,
cord-263699-gosqpg3k	294	3	it	-PRON-	PRP
cord-263699-gosqpg3k	294	4	is	be	VBZ
cord-263699-gosqpg3k	294	5	likely	likely	JJ
cord-263699-gosqpg3k	294	6	that	that	IN
cord-263699-gosqpg3k	294	7	the	the	DT
cord-263699-gosqpg3k	294	8	altered	altered	JJ
cord-263699-gosqpg3k	294	9	post	post	JJ
cord-263699-gosqpg3k	294	10	-	-	JJ
cord-263699-gosqpg3k	294	11	translational	translational	JJ
cord-263699-gosqpg3k	294	12	modification	modification	NN
cord-263699-gosqpg3k	294	13	is	be	VBZ
cord-263699-gosqpg3k	294	14	suffered	suffer	VBN
cord-263699-gosqpg3k	294	15	by	by	IN
cord-263699-gosqpg3k	294	16	NSP4	NSP4	NNP
cord-263699-gosqpg3k	294	17	when	when	WRB
cord-263699-gosqpg3k	294	18	the	the	DT
cord-263699-gosqpg3k	294	19	expression	expression	NN
cord-263699-gosqpg3k	294	20	of	of	IN
cord-263699-gosqpg3k	294	21	GBF1	GBF1	NNP
cord-263699-gosqpg3k	294	22	is	be	VBZ
cord-263699-gosqpg3k	294	23	knocked	knock	VBN
cord-263699-gosqpg3k	294	24	down	down	RP
cord-263699-gosqpg3k	294	25	,	,	,
cord-263699-gosqpg3k	294	26	affects	affect	VBZ
cord-263699-gosqpg3k	294	27	its	-PRON-	PRP$
cord-263699-gosqpg3k	294	28	role	role	NN
cord-263699-gosqpg3k	294	29	in	in	IN
cord-263699-gosqpg3k	294	30	facilitating	facilitate	VBG
cord-263699-gosqpg3k	294	31	(	(	-LRB-
cord-263699-gosqpg3k	294	32	directly	directly	RB
cord-263699-gosqpg3k	294	33	or	or	CC
cord-263699-gosqpg3k	294	34	indirectly	indirectly	RB
cord-263699-gosqpg3k	294	35	)	)	-RRB-
cord-263699-gosqpg3k	295	1	the	the	DT
cord-263699-gosqpg3k	295	2	trimerization	trimerization	NN
cord-263699-gosqpg3k	295	3	of	of	IN
cord-263699-gosqpg3k	295	4	VP7	vp7	NN
cord-263699-gosqpg3k	295	5	.	.	.
cord-263699-gosqpg3k	296	1	It	-PRON-	PRP
cord-263699-gosqpg3k	296	2	can	can	MD
cord-263699-gosqpg3k	296	3	not	not	RB
cord-263699-gosqpg3k	296	4	be	be	VB
cord-263699-gosqpg3k	296	5	discarded	discard	VBN
cord-263699-gosqpg3k	296	6	,	,	,
cord-263699-gosqpg3k	296	7	however	however	RB
cord-263699-gosqpg3k	296	8	,	,	,
cord-263699-gosqpg3k	296	9	that	that	IN
cord-263699-gosqpg3k	296	10	the	the	DT
cord-263699-gosqpg3k	296	11	altered	altered	JJ
cord-263699-gosqpg3k	296	12	glycosylation	glycosylation	NN
cord-263699-gosqpg3k	296	13	pattern	pattern	NN
cord-263699-gosqpg3k	296	14	of	of	IN
cord-263699-gosqpg3k	296	15	VP7	vp7	NN
cord-263699-gosqpg3k	296	16	in	in	IN
cord-263699-gosqpg3k	296	17	the	the	DT
cord-263699-gosqpg3k	296	18	presence	presence	NN
cord-263699-gosqpg3k	296	19	of	of	IN
cord-263699-gosqpg3k	296	20	the	the	DT
cord-263699-gosqpg3k	296	21	pharmacological	pharmacological	JJ
cord-263699-gosqpg3k	296	22	inhibitors	inhibitor	NNS
cord-263699-gosqpg3k	296	23	could	could	MD
cord-263699-gosqpg3k	296	24	also	also	RB
cord-263699-gosqpg3k	296	25	have	have	VB
cord-263699-gosqpg3k	296	26	an	an	DT
cord-263699-gosqpg3k	296	27	impact	impact	NN
cord-263699-gosqpg3k	296	28	in	in	IN
cord-263699-gosqpg3k	296	29	its	-PRON-	PRP$
cord-263699-gosqpg3k	296	30	trimerization	trimerization	NN
cord-263699-gosqpg3k	296	31	.	.	.
cord-263699-gosqpg3k	297	1	The	the	DT
cord-263699-gosqpg3k	297	2	altered	altered	JJ
cord-263699-gosqpg3k	297	3	electrophoretic	electrophoretic	JJ
cord-263699-gosqpg3k	297	4	mobility	mobility	NN
cord-263699-gosqpg3k	297	5	of	of	IN
cord-263699-gosqpg3k	297	6	VP7	vp7	NN
cord-263699-gosqpg3k	297	7	in	in	IN
cord-263699-gosqpg3k	297	8	the	the	DT
cord-263699-gosqpg3k	297	9	presence	presence	NN
cord-263699-gosqpg3k	297	10	of	of	IN
cord-263699-gosqpg3k	297	11	drugs	drug	NNS
cord-263699-gosqpg3k	297	12	or	or	CC
cord-263699-gosqpg3k	297	13	in	in	IN
cord-263699-gosqpg3k	297	14	cells	cell	NNS
cord-263699-gosqpg3k	297	15	depleted	deplete	VBN
cord-263699-gosqpg3k	297	16	of	of	IN
cord-263699-gosqpg3k	297	17	GBF1	GBF1	NNP
cord-263699-gosqpg3k	297	18	has	have	VBZ
cord-263699-gosqpg3k	297	19	been	be	VBN
cord-263699-gosqpg3k	297	20	shown	show	VBN
cord-263699-gosqpg3k	297	21	not	not	RB
cord-263699-gosqpg3k	297	22	to	to	TO
cord-263699-gosqpg3k	297	23	be	be	VB
cord-263699-gosqpg3k	297	24	related	relate	VBN
cord-263699-gosqpg3k	297	25	to	to	IN
cord-263699-gosqpg3k	297	26	N	n	CD
cord-263699-gosqpg3k	297	27	-	-	HYPH
cord-263699-gosqpg3k	297	28	glycosylation	glycosylation	NN
cord-263699-gosqpg3k	297	29	,	,	,
cord-263699-gosqpg3k	297	30	O	o	NN
cord-263699-gosqpg3k	297	31	-	-	HYPH
cord-263699-gosqpg3k	297	32	glycosylation	glycosylation	NN
cord-263699-gosqpg3k	297	33	,	,	,
cord-263699-gosqpg3k	297	34	or	or	CC
cord-263699-gosqpg3k	297	35	phosphorylation	phosphorylation	NN
cord-263699-gosqpg3k	297	36	[	[	-LRB-
cord-263699-gosqpg3k	297	37	76	76	CD
cord-263699-gosqpg3k	297	38	]	]	-RRB-
cord-263699-gosqpg3k	297	39	.	.	.
cord-263699-gosqpg3k	298	1	Given	give	VBN
cord-263699-gosqpg3k	298	2	that	that	IN
cord-263699-gosqpg3k	298	3	GBF1	GBF1	NNP
cord-263699-gosqpg3k	298	4	functions	function	NNS
cord-263699-gosqpg3k	298	5	at	at	IN
cord-263699-gosqpg3k	298	6	the	the	DT
cord-263699-gosqpg3k	298	7	ER	ER	NNP
cord-263699-gosqpg3k	298	8	-	-	HYPH
cord-263699-gosqpg3k	298	9	Golgi	Golgi	NNP
cord-263699-gosqpg3k	298	10	interface	interface	NN
cord-263699-gosqpg3k	298	11	,	,	,
cord-263699-gosqpg3k	298	12	mediating	mediate	VBG
cord-263699-gosqpg3k	298	13	the	the	DT
cord-263699-gosqpg3k	298	14	retrograde	retrograde	JJ
cord-263699-gosqpg3k	298	15	vesicular	vesicular	JJ
cord-263699-gosqpg3k	298	16	transport	transport	NN
cord-263699-gosqpg3k	298	17	,	,	,
cord-263699-gosqpg3k	298	18	and	and	CC
cord-263699-gosqpg3k	298	19	that	that	IN
cord-263699-gosqpg3k	298	20	rotaviruses	rotavirus	NNS
cord-263699-gosqpg3k	298	21	mature	mature	VB
cord-263699-gosqpg3k	298	22	in	in	IN
cord-263699-gosqpg3k	298	23	the	the	DT
cord-263699-gosqpg3k	298	24	ER	ER	NNP
cord-263699-gosqpg3k	298	25	,	,	,
cord-263699-gosqpg3k	298	26	it	-PRON-	PRP
cord-263699-gosqpg3k	298	27	seems	seem	VBZ
cord-263699-gosqpg3k	298	28	likely	likely	JJ
cord-263699-gosqpg3k	298	29	that	that	IN
cord-263699-gosqpg3k	298	30	Golgi	Golgi	NNP
cord-263699-gosqpg3k	298	31	-	-	HYPH
cord-263699-gosqpg3k	298	32	ER	ER	NNP
cord-263699-gosqpg3k	298	33	transport	transport	NN
cord-263699-gosqpg3k	298	34	is	be	VBZ
cord-263699-gosqpg3k	298	35	the	the	DT
cord-263699-gosqpg3k	298	36	relevant	relevant	JJ
cord-263699-gosqpg3k	298	37	process	process	NN
cord-263699-gosqpg3k	298	38	required	require	VBN
cord-263699-gosqpg3k	298	39	for	for	IN
cord-263699-gosqpg3k	298	40	the	the	DT
cord-263699-gosqpg3k	298	41	correct	correct	JJ
cord-263699-gosqpg3k	298	42	maturation	maturation	NN
cord-263699-gosqpg3k	298	43	of	of	IN
cord-263699-gosqpg3k	298	44	rotavirus	rotavirus	NN
cord-263699-gosqpg3k	298	45	.	.	.
cord-263699-gosqpg3k	299	1	However	however	RB
cord-263699-gosqpg3k	299	2	,	,	,
cord-263699-gosqpg3k	299	3	considering	consider	VBG
cord-263699-gosqpg3k	299	4	that	that	IN
cord-263699-gosqpg3k	299	5	LDs	LDs	NNP
cord-263699-gosqpg3k	299	6	have	have	VBP
cord-263699-gosqpg3k	299	7	been	be	VBN
cord-263699-gosqpg3k	299	8	proposed	propose	VBN
cord-263699-gosqpg3k	299	9	to	to	TO
cord-263699-gosqpg3k	299	10	play	play	VB
cord-263699-gosqpg3k	299	11	a	a	DT
cord-263699-gosqpg3k	299	12	significant	significant	JJ
cord-263699-gosqpg3k	299	13	role	role	NN
cord-263699-gosqpg3k	299	14	in	in	IN
cord-263699-gosqpg3k	299	15	the	the	DT
cord-263699-gosqpg3k	299	16	replication	replication	NN
cord-263699-gosqpg3k	299	17	cycle	cycle	NN
cord-263699-gosqpg3k	299	18	of	of	IN
cord-263699-gosqpg3k	299	19	these	these	DT
cord-263699-gosqpg3k	299	20	viruses	virus	NNS
cord-263699-gosqpg3k	299	21	,	,	,
cord-263699-gosqpg3k	299	22	it	-PRON-	PRP
cord-263699-gosqpg3k	299	23	remains	remain	VBZ
cord-263699-gosqpg3k	299	24	possible	possible	JJ
cord-263699-gosqpg3k	299	25	that	that	IN
cord-263699-gosqpg3k	299	26	the	the	DT
cord-263699-gosqpg3k	299	27	protein	protein	NN
cord-263699-gosqpg3k	299	28	transport	transport	NN
cord-263699-gosqpg3k	299	29	between	between	IN
cord-263699-gosqpg3k	299	30	the	the	DT
cord-263699-gosqpg3k	299	31	ER	ER	NNP
cord-263699-gosqpg3k	299	32	and	and	CC
cord-263699-gosqpg3k	299	33	LDs	LDs	NNP
cord-263699-gosqpg3k	299	34	is	be	VBZ
cord-263699-gosqpg3k	299	35	also	also	RB
cord-263699-gosqpg3k	299	36	relevant	relevant	JJ
cord-263699-gosqpg3k	299	37	,	,	,
cord-263699-gosqpg3k	299	38	although	although	IN
cord-263699-gosqpg3k	299	39	,	,	,
cord-263699-gosqpg3k	299	40	a	a	DT
cord-263699-gosqpg3k	299	41	so	so	RB
cord-263699-gosqpg3k	299	42	far	far	RB
cord-263699-gosqpg3k	299	43	uncharacterized	uncharacterized	JJ
cord-263699-gosqpg3k	299	44	function	function	NN
cord-263699-gosqpg3k	299	45	of	of	IN
cord-263699-gosqpg3k	299	46	GBF1	GBF1	NNP
cord-263699-gosqpg3k	299	47	can	can	MD
cord-263699-gosqpg3k	299	48	not	not	RB
cord-263699-gosqpg3k	299	49	be	be	VB
cord-263699-gosqpg3k	299	50	discarded	discard	VBN
cord-263699-gosqpg3k	299	51	.	.	.
cord-263699-gosqpg3k	300	1	On	on	IN
cord-263699-gosqpg3k	300	2	the	the	DT
cord-263699-gosqpg3k	300	3	other	other	JJ
cord-263699-gosqpg3k	300	4	hand	hand	NN
cord-263699-gosqpg3k	300	5	,	,	,
cord-263699-gosqpg3k	300	6	in	in	IN
cord-263699-gosqpg3k	300	7	support	support	NN
cord-263699-gosqpg3k	300	8	of	of	IN
cord-263699-gosqpg3k	300	9	the	the	DT
cord-263699-gosqpg3k	300	10	requirement	requirement	NN
cord-263699-gosqpg3k	300	11	of	of	IN
cord-263699-gosqpg3k	300	12	an	an	DT
cord-263699-gosqpg3k	300	13	active	active	JJ
cord-263699-gosqpg3k	300	14	GBF1	GBF1	NNP
cord-263699-gosqpg3k	300	15	transport	transport	NN
cord-263699-gosqpg3k	300	16	during	during	IN
cord-263699-gosqpg3k	300	17	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	300	18	infection	infection	NN
cord-263699-gosqpg3k	300	19	,	,	,
cord-263699-gosqpg3k	300	20	it	-PRON-	PRP
cord-263699-gosqpg3k	300	21	was	be	VBD
cord-263699-gosqpg3k	300	22	found	find	VBN
cord-263699-gosqpg3k	300	23	that	that	IN
cord-263699-gosqpg3k	300	24	catalytically	catalytically	RB
cord-263699-gosqpg3k	300	25	inactive	inactive	JJ
cord-263699-gosqpg3k	300	26	mutants	mutant	NNS
cord-263699-gosqpg3k	300	27	of	of	IN
cord-263699-gosqpg3k	300	28	GBF1	GBF1	NNP
cord-263699-gosqpg3k	300	29	failed	fail	VBD
cord-263699-gosqpg3k	300	30	to	to	TO
cord-263699-gosqpg3k	300	31	support	support	VB
cord-263699-gosqpg3k	300	32	replication	replication	NN
cord-263699-gosqpg3k	300	33	of	of	IN
cord-263699-gosqpg3k	300	34	the	the	DT
cord-263699-gosqpg3k	300	35	virus	virus	NN
cord-263699-gosqpg3k	300	36	in	in	IN
cord-263699-gosqpg3k	300	37	the	the	DT
cord-263699-gosqpg3k	300	38	presence	presence	NN
cord-263699-gosqpg3k	300	39	of	of	IN
cord-263699-gosqpg3k	300	40	BFA	BFA	NNP
cord-263699-gosqpg3k	300	41	,	,	,
cord-263699-gosqpg3k	300	42	suggesting	suggest	VBG
cord-263699-gosqpg3k	300	43	that	that	IN
cord-263699-gosqpg3k	300	44	GBF1	GBF1	NNP
cord-263699-gosqpg3k	300	45	activity	activity	NN
cord-263699-gosqpg3k	300	46	is	be	VBZ
cord-263699-gosqpg3k	300	47	essential	essential	JJ
cord-263699-gosqpg3k	300	48	for	for	IN
cord-263699-gosqpg3k	300	49	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	300	50	progeny	progeny	NN
cord-263699-gosqpg3k	300	51	production	production	NN
cord-263699-gosqpg3k	300	52	.	.	.
cord-263699-gosqpg3k	301	1	However	however	RB
cord-263699-gosqpg3k	301	2	,	,	,
cord-263699-gosqpg3k	301	3	given	give	VBN
cord-263699-gosqpg3k	301	4	that	that	IN
cord-263699-gosqpg3k	301	5	knocking	knock	VBG
cord-263699-gosqpg3k	301	6	down	down	RP
cord-263699-gosqpg3k	301	7	the	the	DT
cord-263699-gosqpg3k	301	8	expression	expression	NN
cord-263699-gosqpg3k	301	9	of	of	IN
cord-263699-gosqpg3k	301	10	Arf1	Arf1	NNP
cord-263699-gosqpg3k	301	11	was	be	VBD
cord-263699-gosqpg3k	301	12	found	find	VBN
cord-263699-gosqpg3k	301	13	not	not	RB
cord-263699-gosqpg3k	301	14	to	to	TO
cord-263699-gosqpg3k	301	15	affect	affect	VB
cord-263699-gosqpg3k	301	16	the	the	DT
cord-263699-gosqpg3k	301	17	production	production	NN
cord-263699-gosqpg3k	301	18	of	of	IN
cord-263699-gosqpg3k	301	19	infectious	infectious	JJ
cord-263699-gosqpg3k	301	20	virus	virus	NN
cord-263699-gosqpg3k	301	21	,	,	,
cord-263699-gosqpg3k	301	22	it	-PRON-	PRP
cord-263699-gosqpg3k	301	23	is	be	VBZ
cord-263699-gosqpg3k	301	24	likely	likely	JJ
cord-263699-gosqpg3k	301	25	that	that	IN
cord-263699-gosqpg3k	301	26	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	301	27	replication	replication	NN
cord-263699-gosqpg3k	301	28	does	do	VBZ
cord-263699-gosqpg3k	301	29	not	not	RB
cord-263699-gosqpg3k	301	30	depend	depend	VB
cord-263699-gosqpg3k	301	31	on	on	IN
cord-263699-gosqpg3k	301	32	the	the	DT
cord-263699-gosqpg3k	301	33	GBF1	GBF1	NNP
cord-263699-gosqpg3k	301	34	/	/	SYM
cord-263699-gosqpg3k	301	35	Arf1	Arf1	NNP
cord-263699-gosqpg3k	301	36	transport	transport	NN
cord-263699-gosqpg3k	301	37	but	but	CC
cord-263699-gosqpg3k	301	38	might	may	MD
cord-263699-gosqpg3k	301	39	require	require	VB
cord-263699-gosqpg3k	301	40	the	the	DT
cord-263699-gosqpg3k	301	41	activation	activation	NN
cord-263699-gosqpg3k	301	42	of	of	IN
cord-263699-gosqpg3k	301	43	other	other	JJ
cord-263699-gosqpg3k	301	44	GBF1	GBF1	NNP
cord-263699-gosqpg3k	301	45	substrates	substrate	NNS
cord-263699-gosqpg3k	301	46	,	,	,
cord-263699-gosqpg3k	301	47	such	such	JJ
cord-263699-gosqpg3k	301	48	as	as	IN
cord-263699-gosqpg3k	301	49	Arf4	Arf4	NNP
cord-263699-gosqpg3k	301	50	or	or	CC
cord-263699-gosqpg3k	301	51	Arf5	Arf5	NNP
cord-263699-gosqpg3k	301	52	,	,	,
cord-263699-gosqpg3k	301	53	that	that	WDT
cord-263699-gosqpg3k	301	54	could	could	MD
cord-263699-gosqpg3k	301	55	compensate	compensate	VB
cord-263699-gosqpg3k	301	56	for	for	IN
cord-263699-gosqpg3k	301	57	the	the	DT
cord-263699-gosqpg3k	301	58	reduced	reduced	JJ
cord-263699-gosqpg3k	301	59	level	level	NN
cord-263699-gosqpg3k	301	60	of	of	IN
cord-263699-gosqpg3k	301	61	Arf1	Arf1	NNP
cord-263699-gosqpg3k	301	62	.	.	.
cord-263699-gosqpg3k	302	1	Moreover	moreover	RB
cord-263699-gosqpg3k	302	2	,	,	,
cord-263699-gosqpg3k	302	3	it	-PRON-	PRP
cord-263699-gosqpg3k	302	4	was	be	VBD
cord-263699-gosqpg3k	302	5	also	also	RB
cord-263699-gosqpg3k	302	6	found	find	VBN
cord-263699-gosqpg3k	302	7	that	that	IN
cord-263699-gosqpg3k	302	8	while	while	IN
cord-263699-gosqpg3k	302	9	the	the	DT
cord-263699-gosqpg3k	302	10	C	c	NN
cord-263699-gosqpg3k	302	11	-	-	HYPH
cord-263699-gosqpg3k	302	12	terminal	terminal	NN
cord-263699-gosqpg3k	302	13	domain	domain	NN
cord-263699-gosqpg3k	302	14	of	of	IN
cord-263699-gosqpg3k	302	15	GBF1	GBF1	NNP
cord-263699-gosqpg3k	302	16	is	be	VBZ
cord-263699-gosqpg3k	302	17	dispensable	dispensable	JJ
cord-263699-gosqpg3k	302	18	for	for	IN
cord-263699-gosqpg3k	302	19	the	the	DT
cord-263699-gosqpg3k	302	20	viral	viral	JJ
cord-263699-gosqpg3k	302	21	replication	replication	NN
cord-263699-gosqpg3k	302	22	,	,	,
cord-263699-gosqpg3k	302	23	the	the	DT
cord-263699-gosqpg3k	302	24	first	first	JJ
cord-263699-gosqpg3k	302	25	N	n	CD
cord-263699-gosqpg3k	302	26	-	-	HYPH
cord-263699-gosqpg3k	302	27	terminal	terminal	NN
cord-263699-gosqpg3k	302	28	amino	amino	NN
cord-263699-gosqpg3k	302	29	acids	acid	NNS
cord-263699-gosqpg3k	302	30	of	of	IN
cord-263699-gosqpg3k	302	31	this	this	DT
cord-263699-gosqpg3k	302	32	factor	factor	NN
cord-263699-gosqpg3k	302	33	are	be	VBP
cord-263699-gosqpg3k	302	34	essential	essential	JJ
cord-263699-gosqpg3k	302	35	to	to	TO
cord-263699-gosqpg3k	302	36	support	support	VB
cord-263699-gosqpg3k	302	37	replication	replication	NN
cord-263699-gosqpg3k	302	38	of	of	IN
cord-263699-gosqpg3k	302	39	the	the	DT
cord-263699-gosqpg3k	302	40	virus	virus	NN
cord-263699-gosqpg3k	302	41	[	[	-LRB-
cord-263699-gosqpg3k	302	42	76	76	CD
cord-263699-gosqpg3k	302	43	]	]	-RRB-
cord-263699-gosqpg3k	302	44	.	.	.
cord-263699-gosqpg3k	303	1	The	the	DT
cord-263699-gosqpg3k	303	2	requirement	requirement	NN
cord-263699-gosqpg3k	303	3	of	of	IN
cord-263699-gosqpg3k	303	4	the	the	DT
cord-263699-gosqpg3k	303	5	N	n	CD
cord-263699-gosqpg3k	303	6	terminus	terminus	NN
cord-263699-gosqpg3k	303	7	of	of	IN
cord-263699-gosqpg3k	303	8	GBF1	GBF1	NNP
cord-263699-gosqpg3k	303	9	for	for	IN
cord-263699-gosqpg3k	303	10	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	303	11	replication	replication	NN
cord-263699-gosqpg3k	303	12	has	have	VBZ
cord-263699-gosqpg3k	303	13	also	also	RB
cord-263699-gosqpg3k	303	14	been	be	VBN
cord-263699-gosqpg3k	303	15	reported	report	VBN
cord-263699-gosqpg3k	303	16	to	to	TO
cord-263699-gosqpg3k	303	17	be	be	VB
cord-263699-gosqpg3k	303	18	essential	essential	JJ
cord-263699-gosqpg3k	303	19	for	for	IN
cord-263699-gosqpg3k	303	20	the	the	DT
cord-263699-gosqpg3k	303	21	replication	replication	NN
cord-263699-gosqpg3k	303	22	of	of	IN
cord-263699-gosqpg3k	303	23	CVB3	CVB3	NNPS
cord-263699-gosqpg3k	303	24	and	and	CC
cord-263699-gosqpg3k	303	25	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	303	26	(	(	-LRB-
cord-263699-gosqpg3k	303	27	see	see	VB
cord-263699-gosqpg3k	303	28	above	above	RB
cord-263699-gosqpg3k	303	29	)	)	-RRB-
cord-263699-gosqpg3k	303	30	.	.	.
cord-263699-gosqpg3k	304	1	Thus	thus	RB
cord-263699-gosqpg3k	304	2	,	,	,
cord-263699-gosqpg3k	304	3	these	these	DT
cord-263699-gosqpg3k	304	4	results	result	NNS
cord-263699-gosqpg3k	304	5	might	may	MD
cord-263699-gosqpg3k	304	6	indicate	indicate	VB
cord-263699-gosqpg3k	304	7	that	that	IN
cord-263699-gosqpg3k	304	8	GBF1	GBF1	NNP
cord-263699-gosqpg3k	304	9	could	could	MD
cord-263699-gosqpg3k	304	10	bind	bind	VB
cord-263699-gosqpg3k	304	11	a	a	DT
cord-263699-gosqpg3k	304	12	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	304	13	protein	protein	NN
cord-263699-gosqpg3k	304	14	,	,	,
cord-263699-gosqpg3k	304	15	similar	similar	JJ
cord-263699-gosqpg3k	304	16	to	to	IN
cord-263699-gosqpg3k	304	17	what	what	WP
cord-263699-gosqpg3k	304	18	has	have	VBZ
cord-263699-gosqpg3k	304	19	been	be	VBN
cord-263699-gosqpg3k	304	20	observed	observe	VBN
cord-263699-gosqpg3k	304	21	with	with	IN
cord-263699-gosqpg3k	304	22	the	the	DT
cord-263699-gosqpg3k	304	23	picornavirus	picornavirus	NNP
cord-263699-gosqpg3k	304	24	3A	3A	NNP
cord-263699-gosqpg3k	304	25	protein	protein	NNP
cord-263699-gosqpg3k	304	26	.	.	.
cord-263699-gosqpg3k	305	1	However	however	RB
cord-263699-gosqpg3k	305	2	,	,	,
cord-263699-gosqpg3k	305	3	an	an	DT
cord-263699-gosqpg3k	305	4	interaction	interaction	NN
cord-263699-gosqpg3k	305	5	of	of	IN
cord-263699-gosqpg3k	305	6	GBF1	GBF1	NNP
cord-263699-gosqpg3k	305	7	with	with	IN
cord-263699-gosqpg3k	305	8	a	a	DT
cord-263699-gosqpg3k	305	9	cellular	cellular	JJ
cord-263699-gosqpg3k	305	10	factor	factor	NN
cord-263699-gosqpg3k	305	11	might	may	MD
cord-263699-gosqpg3k	305	12	also	also	RB
cord-263699-gosqpg3k	305	13	be	be	VB
cord-263699-gosqpg3k	305	14	important	important	JJ
cord-263699-gosqpg3k	305	15	for	for	IN
cord-263699-gosqpg3k	305	16	virus	virus	NN
cord-263699-gosqpg3k	305	17	replication	replication	NN
cord-263699-gosqpg3k	305	18	.	.	.
cord-263699-gosqpg3k	306	1	Further	further	JJ
cord-263699-gosqpg3k	306	2	experiments	experiment	NNS
cord-263699-gosqpg3k	306	3	have	have	VBP
cord-263699-gosqpg3k	306	4	to	to	TO
cord-263699-gosqpg3k	306	5	be	be	VB
cord-263699-gosqpg3k	306	6	carried	carry	VBN
cord-263699-gosqpg3k	306	7	out	out	RP
cord-263699-gosqpg3k	306	8	to	to	TO
cord-263699-gosqpg3k	306	9	explore	explore	VB
cord-263699-gosqpg3k	306	10	in	in	IN
cord-263699-gosqpg3k	306	11	more	more	JJR
cord-263699-gosqpg3k	306	12	detail	detail	NN
cord-263699-gosqpg3k	306	13	the	the	DT
cord-263699-gosqpg3k	306	14	mechanism	mechanism	NN
cord-263699-gosqpg3k	306	15	through	through	IN
cord-263699-gosqpg3k	306	16	which	which	WDT
cord-263699-gosqpg3k	306	17	GBF1	GBF1	NNP
cord-263699-gosqpg3k	306	18	supports	support	VBZ
cord-263699-gosqpg3k	306	19	the	the	DT
cord-263699-gosqpg3k	306	20	replication	replication	NN
cord-263699-gosqpg3k	306	21	cycle	cycle	NN
cord-263699-gosqpg3k	306	22	of	of	IN
cord-263699-gosqpg3k	306	23	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	306	24	replication	replication	NN
cord-263699-gosqpg3k	306	25	.	.	.
cord-263699-gosqpg3k	307	1	As	as	IN
cord-263699-gosqpg3k	307	2	intracellular	intracellular	JJ
cord-263699-gosqpg3k	307	3	pathogens	pathogen	NNS
cord-263699-gosqpg3k	307	4	,	,	,
cord-263699-gosqpg3k	307	5	the	the	DT
cord-263699-gosqpg3k	307	6	infection	infection	NN
cord-263699-gosqpg3k	307	7	of	of	IN
cord-263699-gosqpg3k	307	8	viruses	virus	NNS
cord-263699-gosqpg3k	307	9	depends	depend	VBZ
cord-263699-gosqpg3k	307	10	on	on	IN
cord-263699-gosqpg3k	307	11	their	-PRON-	PRP$
cord-263699-gosqpg3k	307	12	capacity	capacity	NN
cord-263699-gosqpg3k	307	13	to	to	TO
cord-263699-gosqpg3k	307	14	replicate	replicate	VB
cord-263699-gosqpg3k	307	15	successfully	successfully	RB
cord-263699-gosqpg3k	307	16	within	within	IN
cord-263699-gosqpg3k	307	17	the	the	DT
cord-263699-gosqpg3k	307	18	host	host	NN
cord-263699-gosqpg3k	307	19	cell	cell	NN
cord-263699-gosqpg3k	307	20	.	.	.
cord-263699-gosqpg3k	308	1	The	the	DT
cord-263699-gosqpg3k	308	2	restricted	restricted	JJ
cord-263699-gosqpg3k	308	3	coding	code	VBG
cord-263699-gosqpg3k	308	4	potential	potential	NN
cord-263699-gosqpg3k	308	5	imposed	impose	VBN
cord-263699-gosqpg3k	308	6	by	by	IN
cord-263699-gosqpg3k	308	7	the	the	DT
cord-263699-gosqpg3k	308	8	small	small	JJ
cord-263699-gosqpg3k	308	9	size	size	NN
cord-263699-gosqpg3k	308	10	of	of	IN
cord-263699-gosqpg3k	308	11	viral	viral	JJ
cord-263699-gosqpg3k	308	12	genomes	genome	NNS
cord-263699-gosqpg3k	308	13	had	have	VBD
cord-263699-gosqpg3k	308	14	led	lead	VBN
cord-263699-gosqpg3k	308	15	the	the	DT
cord-263699-gosqpg3k	308	16	viruses	virus	NNS
cord-263699-gosqpg3k	308	17	to	to	TO
cord-263699-gosqpg3k	308	18	hijack	hijack	VB
cord-263699-gosqpg3k	308	19	essential	essential	JJ
cord-263699-gosqpg3k	308	20	systems	system	NNS
cord-263699-gosqpg3k	308	21	of	of	IN
cord-263699-gosqpg3k	308	22	cellular	cellular	JJ
cord-263699-gosqpg3k	308	23	functions	function	NNS
cord-263699-gosqpg3k	308	24	to	to	TO
cord-263699-gosqpg3k	308	25	facilitate	facilitate	VB
cord-263699-gosqpg3k	308	26	their	-PRON-	PRP$
cord-263699-gosqpg3k	308	27	replication	replication	NN
cord-263699-gosqpg3k	308	28	.	.	.
cord-263699-gosqpg3k	309	1	In	in	IN
cord-263699-gosqpg3k	309	2	this	this	DT
cord-263699-gosqpg3k	309	3	regard	regard	NN
cord-263699-gosqpg3k	309	4	,	,	,
cord-263699-gosqpg3k	309	5	emerging	emerge	VBG
cord-263699-gosqpg3k	309	6	data	datum	NNS
cord-263699-gosqpg3k	309	7	have	have	VBP
cord-263699-gosqpg3k	309	8	shown	show	VBN
cord-263699-gosqpg3k	309	9	that	that	IN
cord-263699-gosqpg3k	309	10	many	many	JJ
cord-263699-gosqpg3k	309	11	cellular	cellular	JJ
cord-263699-gosqpg3k	309	12	factors	factor	NNS
cord-263699-gosqpg3k	309	13	are	be	VBP
cord-263699-gosqpg3k	309	14	susceptible	susceptible	JJ
cord-263699-gosqpg3k	309	15	to	to	TO
cord-263699-gosqpg3k	309	16	be	be	VB
cord-263699-gosqpg3k	309	17	reprogrammed	reprogramme	VBN
cord-263699-gosqpg3k	309	18	during	during	IN
cord-263699-gosqpg3k	309	19	viral	viral	JJ
cord-263699-gosqpg3k	309	20	infections	infection	NNS
cord-263699-gosqpg3k	309	21	to	to	TO
cord-263699-gosqpg3k	309	22	perform	perform	VB
cord-263699-gosqpg3k	309	23	novel	novel	JJ
cord-263699-gosqpg3k	309	24	functions	function	NNS
cord-263699-gosqpg3k	309	25	that	that	WDT
cord-263699-gosqpg3k	309	26	benefit	benefit	VBP
cord-263699-gosqpg3k	309	27	these	these	DT
cord-263699-gosqpg3k	309	28	pathogens	pathogen	NNS
cord-263699-gosqpg3k	309	29	.	.	.
cord-263699-gosqpg3k	310	1	One	one	CD
cord-263699-gosqpg3k	310	2	of	of	IN
cord-263699-gosqpg3k	310	3	these	these	DT
cord-263699-gosqpg3k	310	4	cellular	cellular	JJ
cord-263699-gosqpg3k	310	5	elements	element	NNS
cord-263699-gosqpg3k	310	6	is	be	VBZ
cord-263699-gosqpg3k	310	7	the	the	DT
cord-263699-gosqpg3k	310	8	guanine	guanine	NN
cord-263699-gosqpg3k	310	9	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	310	10	exchange	exchange	NN
cord-263699-gosqpg3k	310	11	factor	factor	NN
cord-263699-gosqpg3k	310	12	GBF1	GBF1	NNP
cord-263699-gosqpg3k	310	13	,	,	,
cord-263699-gosqpg3k	310	14	which	which	WDT
cord-263699-gosqpg3k	310	15	has	have	VBZ
cord-263699-gosqpg3k	310	16	proved	prove	VBN
cord-263699-gosqpg3k	310	17	to	to	TO
cord-263699-gosqpg3k	310	18	be	be	VB
cord-263699-gosqpg3k	310	19	essential	essential	JJ
cord-263699-gosqpg3k	310	20	for	for	IN
cord-263699-gosqpg3k	310	21	the	the	DT
cord-263699-gosqpg3k	310	22	efficient	efficient	JJ
cord-263699-gosqpg3k	310	23	replication	replication	NN
cord-263699-gosqpg3k	310	24	of	of	IN
cord-263699-gosqpg3k	310	25	many	many	JJ
cord-263699-gosqpg3k	310	26	RNA	RNA	NNP
cord-263699-gosqpg3k	310	27	viruses	virus	NNS
cord-263699-gosqpg3k	310	28	.	.	.
cord-263699-gosqpg3k	311	1	It	-PRON-	PRP
cord-263699-gosqpg3k	311	2	has	have	VBZ
cord-263699-gosqpg3k	311	3	been	be	VBN
cord-263699-gosqpg3k	311	4	shown	show	VBN
cord-263699-gosqpg3k	311	5	to	to	TO
cord-263699-gosqpg3k	311	6	be	be	VB
cord-263699-gosqpg3k	311	7	required	require	VBN
cord-263699-gosqpg3k	311	8	for	for	IN
cord-263699-gosqpg3k	311	9	different	different	JJ
cord-263699-gosqpg3k	311	10	stages	stage	NNS
cord-263699-gosqpg3k	311	11	of	of	IN
cord-263699-gosqpg3k	311	12	the	the	DT
cord-263699-gosqpg3k	311	13	virus	virus	NN
cord-263699-gosqpg3k	311	14	lifecycles	lifecycle	NNS
cord-263699-gosqpg3k	311	15	,	,	,
cord-263699-gosqpg3k	311	16	including	include	VBG
cord-263699-gosqpg3k	311	17	the	the	DT
cord-263699-gosqpg3k	311	18	formation	formation	NN
cord-263699-gosqpg3k	311	19	and	and	CC
cord-263699-gosqpg3k	311	20	maturation	maturation	NN
cord-263699-gosqpg3k	311	21	of	of	IN
cord-263699-gosqpg3k	311	22	viral	viral	JJ
cord-263699-gosqpg3k	311	23	replication	replication	NN
cord-263699-gosqpg3k	311	24	complexes	complex	NNS
cord-263699-gosqpg3k	311	25	as	as	RB
cord-263699-gosqpg3k	311	26	well	well	RB
cord-263699-gosqpg3k	311	27	as	as	IN
cord-263699-gosqpg3k	311	28	the	the	DT
cord-263699-gosqpg3k	311	29	coordination	coordination	NN
cord-263699-gosqpg3k	311	30	of	of	IN
cord-263699-gosqpg3k	311	31	RNA	RNA	NNP
cord-263699-gosqpg3k	311	32	genome	genome	NN
cord-263699-gosqpg3k	311	33	replication	replication	NN
cord-263699-gosqpg3k	311	34	,	,	,
cord-263699-gosqpg3k	311	35	virus	virus	NN
cord-263699-gosqpg3k	311	36	assembly	assembly	NN
cord-263699-gosqpg3k	311	37	,	,	,
cord-263699-gosqpg3k	311	38	and	and	CC
cord-263699-gosqpg3k	311	39	release	release	NN
cord-263699-gosqpg3k	311	40	.	.	.
cord-263699-gosqpg3k	312	1	The	the	DT
cord-263699-gosqpg3k	312	2	role	role	NN
cord-263699-gosqpg3k	312	3	of	of	IN
cord-263699-gosqpg3k	312	4	GBF1	GBF1	NNP
cord-263699-gosqpg3k	312	5	has	have	VBZ
cord-263699-gosqpg3k	312	6	been	be	VBN
cord-263699-gosqpg3k	312	7	found	find	VBN
cord-263699-gosqpg3k	312	8	,	,	,
cord-263699-gosqpg3k	312	9	principally	principally	RB
cord-263699-gosqpg3k	312	10	,	,	,
cord-263699-gosqpg3k	312	11	to	to	TO
cord-263699-gosqpg3k	312	12	depend	depend	VB
cord-263699-gosqpg3k	312	13	on	on	IN
cord-263699-gosqpg3k	312	14	its	-PRON-	PRP$
cord-263699-gosqpg3k	312	15	ability	ability	NN
cord-263699-gosqpg3k	312	16	to	to	TO
cord-263699-gosqpg3k	312	17	activate	activate	VB
cord-263699-gosqpg3k	312	18	distinct	distinct	JJ
cord-263699-gosqpg3k	312	19	Arf	Arf	NNP
cord-263699-gosqpg3k	312	20	proteins	protein	NNS
cord-263699-gosqpg3k	312	21	,	,	,
cord-263699-gosqpg3k	312	22	to	to	TO
cord-263699-gosqpg3k	312	23	regulate	regulate	VB
cord-263699-gosqpg3k	312	24	different	different	JJ
cord-263699-gosqpg3k	312	25	transport	transport	NN
cord-263699-gosqpg3k	312	26	pathways	pathway	NNS
cord-263699-gosqpg3k	312	27	that	that	WDT
cord-263699-gosqpg3k	312	28	permit	permit	VBP
cord-263699-gosqpg3k	312	29	the	the	DT
cord-263699-gosqpg3k	312	30	communication	communication	NN
cord-263699-gosqpg3k	312	31	between	between	IN
cord-263699-gosqpg3k	312	32	the	the	DT
cord-263699-gosqpg3k	312	33	viral	viral	JJ
cord-263699-gosqpg3k	312	34	replication	replication	NN
cord-263699-gosqpg3k	312	35	organelles	organelle	NNS
cord-263699-gosqpg3k	312	36	and	and	CC
cord-263699-gosqpg3k	312	37	cellular	cellular	JJ
cord-263699-gosqpg3k	312	38	organelles	organelle	NNS
cord-263699-gosqpg3k	312	39	(	(	-LRB-
cord-263699-gosqpg3k	312	40	ER	ER	NNP
cord-263699-gosqpg3k	312	41	and	and	CC
cord-263699-gosqpg3k	312	42	LDs	LDs	NNP
cord-263699-gosqpg3k	312	43	)	)	-RRB-
cord-263699-gosqpg3k	312	44	involved	involve	VBN
cord-263699-gosqpg3k	312	45	in	in	IN
cord-263699-gosqpg3k	312	46	virus	virus	NN
cord-263699-gosqpg3k	312	47	infection	infection	NN
cord-263699-gosqpg3k	312	48	.	.	.
cord-263699-gosqpg3k	313	1	However	however	RB
cord-263699-gosqpg3k	313	2	,	,	,
cord-263699-gosqpg3k	313	3	for	for	IN
cord-263699-gosqpg3k	313	4	many	many	JJ
cord-263699-gosqpg3k	313	5	viruses	virus	NNS
cord-263699-gosqpg3k	313	6	,	,	,
cord-263699-gosqpg3k	313	7	the	the	DT
cord-263699-gosqpg3k	313	8	role	role	NN
cord-263699-gosqpg3k	313	9	of	of	IN
cord-263699-gosqpg3k	313	10	GBF1	GBF1	NNP
cord-263699-gosqpg3k	313	11	in	in	IN
cord-263699-gosqpg3k	313	12	virus	virus	NN
cord-263699-gosqpg3k	313	13	replication	replication	NN
cord-263699-gosqpg3k	313	14	has	have	VBZ
cord-263699-gosqpg3k	313	15	also	also	RB
cord-263699-gosqpg3k	313	16	been	be	VBN
cord-263699-gosqpg3k	313	17	shown	show	VBN
cord-263699-gosqpg3k	313	18	not	not	RB
cord-263699-gosqpg3k	313	19	to	to	TO
cord-263699-gosqpg3k	313	20	depend	depend	VB
cord-263699-gosqpg3k	313	21	on	on	IN
cord-263699-gosqpg3k	313	22	the	the	DT
cord-263699-gosqpg3k	313	23	catalytic	catalytic	JJ
cord-263699-gosqpg3k	313	24	activity	activity	NN
cord-263699-gosqpg3k	313	25	of	of	IN
cord-263699-gosqpg3k	313	26	the	the	DT
cord-263699-gosqpg3k	313	27	protein	protein	NN
cord-263699-gosqpg3k	313	28	.	.	.
cord-263699-gosqpg3k	314	1	Although	although	IN
cord-263699-gosqpg3k	314	2	it	-PRON-	PRP
cord-263699-gosqpg3k	314	3	is	be	VBZ
cord-263699-gosqpg3k	314	4	not	not	RB
cord-263699-gosqpg3k	314	5	well	well	RB
cord-263699-gosqpg3k	314	6	understood	understand	VBN
cord-263699-gosqpg3k	314	7	how	how	WRB
cord-263699-gosqpg3k	314	8	GBF1	GBF1	NNP
cord-263699-gosqpg3k	314	9	could	could	MD
cord-263699-gosqpg3k	314	10	exert	exert	VB
cord-263699-gosqpg3k	314	11	this	this	DT
cord-263699-gosqpg3k	314	12	non	non	JJ
cord-263699-gosqpg3k	314	13	-	-	JJ
cord-263699-gosqpg3k	314	14	catalytic	catalytic	JJ
cord-263699-gosqpg3k	314	15	activity	activity	NN
cord-263699-gosqpg3k	314	16	,	,	,
cord-263699-gosqpg3k	314	17	the	the	DT
cord-263699-gosqpg3k	314	18	multidomain	multidomain	NN
cord-263699-gosqpg3k	314	19	structure	structure	NN
cord-263699-gosqpg3k	314	20	of	of	IN
cord-263699-gosqpg3k	314	21	the	the	DT
cord-263699-gosqpg3k	314	22	protein	protein	NN
cord-263699-gosqpg3k	314	23	seems	seem	VBZ
cord-263699-gosqpg3k	314	24	to	to	TO
cord-263699-gosqpg3k	314	25	play	play	VB
cord-263699-gosqpg3k	314	26	an	an	DT
cord-263699-gosqpg3k	314	27	essential	essential	JJ
cord-263699-gosqpg3k	314	28	role	role	NN
cord-263699-gosqpg3k	314	29	by	by	IN
cord-263699-gosqpg3k	314	30	permitting	permit	VBG
cord-263699-gosqpg3k	314	31	GBF1	GBF1	NNP
cord-263699-gosqpg3k	314	32	to	to	TO
cord-263699-gosqpg3k	314	33	engage	engage	VB
cord-263699-gosqpg3k	314	34	in	in	IN
cord-263699-gosqpg3k	314	35	the	the	DT
cord-263699-gosqpg3k	314	36	interaction	interaction	NN
cord-263699-gosqpg3k	314	37	with	with	IN
cord-263699-gosqpg3k	314	38	many	many	JJ
cord-263699-gosqpg3k	314	39	cellular	cellular	JJ
cord-263699-gosqpg3k	314	40	and	and	CC
cord-263699-gosqpg3k	314	41	viral	viral	JJ
cord-263699-gosqpg3k	314	42	proteins	protein	NNS
cord-263699-gosqpg3k	314	43	that	that	WDT
cord-263699-gosqpg3k	314	44	seems	seem	VBZ
cord-263699-gosqpg3k	314	45	to	to	TO
cord-263699-gosqpg3k	314	46	regulate	regulate	VB
cord-263699-gosqpg3k	314	47	,	,	,
cord-263699-gosqpg3k	314	48	directly	directly	RB
cord-263699-gosqpg3k	314	49	or	or	CC
cord-263699-gosqpg3k	314	50	indirectly	indirectly	RB
cord-263699-gosqpg3k	314	51	,	,	,
cord-263699-gosqpg3k	314	52	viral	viral	JJ
cord-263699-gosqpg3k	314	53	replication	replication	NN
cord-263699-gosqpg3k	314	54	.	.	.
cord-263699-gosqpg3k	315	1	The	the	DT
cord-263699-gosqpg3k	315	2	relevance	relevance	NN
cord-263699-gosqpg3k	315	3	of	of	IN
cord-263699-gosqpg3k	315	4	GBF1	GBF1	NNP
cord-263699-gosqpg3k	315	5	for	for	IN
cord-263699-gosqpg3k	315	6	the	the	DT
cord-263699-gosqpg3k	315	7	replication	replication	NN
cord-263699-gosqpg3k	315	8	of	of	IN
cord-263699-gosqpg3k	315	9	several	several	JJ
cord-263699-gosqpg3k	315	10	RNA	RNA	NNP
cord-263699-gosqpg3k	315	11	viruses	virus	NNS
cord-263699-gosqpg3k	315	12	identifies	identify	VBZ
cord-263699-gosqpg3k	315	13	this	this	DT
cord-263699-gosqpg3k	315	14	factor	factor	NN
cord-263699-gosqpg3k	315	15	as	as	IN
cord-263699-gosqpg3k	315	16	a	a	DT
cord-263699-gosqpg3k	315	17	potential	potential	JJ
cord-263699-gosqpg3k	315	18	candidate	candidate	NN
cord-263699-gosqpg3k	315	19	for	for	IN
cord-263699-gosqpg3k	315	20	antiviral	antiviral	JJ
cord-263699-gosqpg3k	315	21	therapies	therapy	NNS
cord-263699-gosqpg3k	315	22	to	to	TO
cord-263699-gosqpg3k	315	23	control	control	VB
cord-263699-gosqpg3k	315	24	a	a	DT
cord-263699-gosqpg3k	315	25	broad	broad	JJ
cord-263699-gosqpg3k	315	26	-	-	HYPH
cord-263699-gosqpg3k	315	27	spectrum	spectrum	NN
cord-263699-gosqpg3k	315	28	of	of	IN
cord-263699-gosqpg3k	315	29	viral	viral	JJ
cord-263699-gosqpg3k	315	30	infections	infection	NNS
cord-263699-gosqpg3k	315	31	.	.	.
cord-263699-gosqpg3k	316	1	However	however	RB
cord-263699-gosqpg3k	316	2	,	,	,
cord-263699-gosqpg3k	316	3	given	give	VBN
cord-263699-gosqpg3k	316	4	the	the	DT
cord-263699-gosqpg3k	316	5	essential	essential	JJ
cord-263699-gosqpg3k	316	6	role	role	NN
cord-263699-gosqpg3k	316	7	of	of	IN
cord-263699-gosqpg3k	316	8	GBF1	GBF1	NNP
cord-263699-gosqpg3k	316	9	in	in	IN
cord-263699-gosqpg3k	316	10	the	the	DT
cord-263699-gosqpg3k	316	11	secretory	secretory	JJ
cord-263699-gosqpg3k	316	12	pathway	pathway	NN
cord-263699-gosqpg3k	316	13	,	,	,
cord-263699-gosqpg3k	316	14	and	and	CC
cord-263699-gosqpg3k	316	15	in	in	IN
cord-263699-gosqpg3k	316	16	other	other	JJ
cord-263699-gosqpg3k	316	17	so	so	RB
cord-263699-gosqpg3k	316	18	far	far	RB
cord-263699-gosqpg3k	316	19	ill	ill	RB
cord-263699-gosqpg3k	316	20	-	-	HYPH
cord-263699-gosqpg3k	316	21	characterized	characterize	VBN
cord-263699-gosqpg3k	316	22	functions	function	NNS
cord-263699-gosqpg3k	316	23	of	of	IN
cord-263699-gosqpg3k	316	24	the	the	DT
cord-263699-gosqpg3k	316	25	cell	cell	NN
cord-263699-gosqpg3k	316	26	,	,	,
cord-263699-gosqpg3k	316	27	the	the	DT
cord-263699-gosqpg3k	316	28	development	development	NN
cord-263699-gosqpg3k	316	29	of	of	IN
cord-263699-gosqpg3k	316	30	safe	safe	JJ
cord-263699-gosqpg3k	316	31	and	and	CC
cord-263699-gosqpg3k	316	32	effective	effective	JJ
cord-263699-gosqpg3k	316	33	antiviral	antiviral	JJ
cord-263699-gosqpg3k	316	34	therapies	therapy	NNS
cord-263699-gosqpg3k	316	35	that	that	WDT
cord-263699-gosqpg3k	316	36	could	could	MD
cord-263699-gosqpg3k	316	37	help	help	VB
cord-263699-gosqpg3k	316	38	to	to	TO
cord-263699-gosqpg3k	316	39	deal	deal	VB
cord-263699-gosqpg3k	316	40	with	with	IN
cord-263699-gosqpg3k	316	41	viral	viral	JJ
cord-263699-gosqpg3k	316	42	infections	infection	NNS
cord-263699-gosqpg3k	316	43	,	,	,
cord-263699-gosqpg3k	316	44	without	without	IN
cord-263699-gosqpg3k	316	45	harming	harm	VBG
cord-263699-gosqpg3k	316	46	the	the	DT
cord-263699-gosqpg3k	316	47	host	host	NN
cord-263699-gosqpg3k	316	48	cells	cell	NNS
cord-263699-gosqpg3k	316	49	,	,	,
cord-263699-gosqpg3k	316	50	represents	represent	VBZ
cord-263699-gosqpg3k	316	51	a	a	DT
cord-263699-gosqpg3k	316	52	challenging	challenging	JJ
cord-263699-gosqpg3k	316	53	mission	mission	NN
cord-263699-gosqpg3k	316	54	.	.	.
cord-263699-gosqpg3k	317	1	In	in	IN
cord-263699-gosqpg3k	317	2	conclusion	conclusion	NN
cord-263699-gosqpg3k	317	3	,	,	,
cord-263699-gosqpg3k	317	4	the	the	DT
cord-263699-gosqpg3k	317	5	data	datum	NNS
cord-263699-gosqpg3k	317	6	discussed	discuss	VBN
cord-263699-gosqpg3k	317	7	in	in	IN
cord-263699-gosqpg3k	317	8	this	this	DT
cord-263699-gosqpg3k	317	9	review	review	NN
cord-263699-gosqpg3k	317	10	bring	bre	VBG
cord-263699-gosqpg3k	317	11	to	to	TO
cord-263699-gosqpg3k	317	12	light	light	VB
cord-263699-gosqpg3k	317	13	a	a	DT
cord-263699-gosqpg3k	317	14	new	new	JJ
cord-263699-gosqpg3k	317	15	diverse	diverse	JJ
cord-263699-gosqpg3k	317	16	range	range	NN
cord-263699-gosqpg3k	317	17	of	of	IN
cord-263699-gosqpg3k	317	18	functions	function	NNS
cord-263699-gosqpg3k	317	19	of	of	IN
cord-263699-gosqpg3k	317	20	GBF1	GBF1	NNP
cord-263699-gosqpg3k	317	21	that	that	WDT
cord-263699-gosqpg3k	317	22	might	may	MD
cord-263699-gosqpg3k	317	23	explain	explain	VB
cord-263699-gosqpg3k	317	24	how	how	WRB
cord-263699-gosqpg3k	317	25	this	this	DT
cord-263699-gosqpg3k	317	26	factor	factor	NN
cord-263699-gosqpg3k	317	27	serves	serve	VBZ
cord-263699-gosqpg3k	317	28	for	for	IN
cord-263699-gosqpg3k	317	29	so	so	RB
cord-263699-gosqpg3k	317	30	many	many	JJ
cord-263699-gosqpg3k	317	31	processes	process	NNS
cord-263699-gosqpg3k	317	32	in	in	IN
cord-263699-gosqpg3k	317	33	different	different	JJ
cord-263699-gosqpg3k	317	34	compartments	compartment	NNS
cord-263699-gosqpg3k	317	35	of	of	IN
cord-263699-gosqpg3k	317	36	the	the	DT
cord-263699-gosqpg3k	317	37	cell	cell	NN
cord-263699-gosqpg3k	317	38	.	.	.
cord-263699-gosqpg3k	318	1	Future	future	JJ
cord-263699-gosqpg3k	318	2	studies	study	NNS
cord-263699-gosqpg3k	318	3	aimed	aim	VBN
cord-263699-gosqpg3k	318	4	to	to	TO
cord-263699-gosqpg3k	318	5	clarify	clarify	VB
cord-263699-gosqpg3k	318	6	the	the	DT
cord-263699-gosqpg3k	318	7	mechanisms	mechanism	NNS
cord-263699-gosqpg3k	318	8	underlying	underlie	VBG
cord-263699-gosqpg3k	318	9	the	the	DT
cord-263699-gosqpg3k	318	10	multiple	multiple	JJ
cord-263699-gosqpg3k	318	11	functions	function	NNS
cord-263699-gosqpg3k	318	12	associated	associate	VBN
cord-263699-gosqpg3k	318	13	with	with	IN
cord-263699-gosqpg3k	318	14	this	this	DT
cord-263699-gosqpg3k	318	15	interesting	interesting	JJ
cord-263699-gosqpg3k	318	16	molecule	molecule	NN
cord-263699-gosqpg3k	318	17	would	would	MD
cord-263699-gosqpg3k	318	18	help	help	VB
cord-263699-gosqpg3k	318	19	to	to	TO
cord-263699-gosqpg3k	318	20	advance	advance	VB
cord-263699-gosqpg3k	318	21	our	-PRON-	PRP$
cord-263699-gosqpg3k	318	22	understanding	understanding	NN
cord-263699-gosqpg3k	318	23	of	of	IN
cord-263699-gosqpg3k	318	24	virus	virus	NN
cord-263699-gosqpg3k	318	25	and	and	CC
cord-263699-gosqpg3k	318	26	cell	cell	NN
cord-263699-gosqpg3k	318	27	biology	biology	NN
cord-263699-gosqpg3k	318	28	.	.	.
cord-263699-gosqpg3k	319	1	Funding	funding	NN
cord-263699-gosqpg3k	319	2	:	:	:
cord-263699-gosqpg3k	320	1	Some	some	DT
cord-263699-gosqpg3k	320	2	of	of	IN
cord-263699-gosqpg3k	320	3	the	the	DT
cord-263699-gosqpg3k	320	4	data	datum	NNS
cord-263699-gosqpg3k	320	5	reported	report	VBN
cord-263699-gosqpg3k	320	6	in	in	IN
cord-263699-gosqpg3k	320	7	this	this	DT
cord-263699-gosqpg3k	320	8	review	review	NN
cord-263699-gosqpg3k	320	9	was	be	VBD
cord-263699-gosqpg3k	320	10	partially	partially	RB
cord-263699-gosqpg3k	320	11	supported	support	VBN
cord-263699-gosqpg3k	320	12	by	by	IN
cord-263699-gosqpg3k	320	13	grant	grant	NN
cord-263699-gosqpg3k	320	14	IG200317	ig200317	NN
cord-263699-gosqpg3k	320	15	from	from	IN
cord-263699-gosqpg3k	320	16	DGAPA	DGAPA	NNP
cord-263699-gosqpg3k	320	17	-	-	HYPH
cord-263699-gosqpg3k	320	18	PAPIIT	PAPIIT	NNP
cord-263699-gosqpg3k	320	19	/	/	SYM
cord-263699-gosqpg3k	320	20	UNAM	UNAM	NNP
cord-263699-gosqpg3k	320	21	.	.	.
cord-263699-gosqpg3k	321	1	Intracellular	Intracellular	NNP
cord-263699-gosqpg3k	321	2	Vesicular	Vesicular	NNP
cord-263699-gosqpg3k	321	3	Traffic	traffic	NN
cord-263699-gosqpg3k	322	1	Dissecting	dissect	VBG
cord-263699-gosqpg3k	322	2	the	the	DT
cord-263699-gosqpg3k	322	3	role	role	NN
cord-263699-gosqpg3k	322	4	of	of	IN
cord-263699-gosqpg3k	322	5	the	the	DT
cord-263699-gosqpg3k	322	6	Arf	Arf	NNP
cord-263699-gosqpg3k	322	7	guanine	guanine	NN
cord-263699-gosqpg3k	322	8	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	322	9	exchange	exchange	NN
cord-263699-gosqpg3k	322	10	factor	factor	NN
cord-263699-gosqpg3k	322	11	GBF1	GBF1	NNP
cord-263699-gosqpg3k	322	12	in	in	IN
cord-263699-gosqpg3k	322	13	Golgi	Golgi	NNP
cord-263699-gosqpg3k	322	14	biogenesis	biogenesis	NN
cord-263699-gosqpg3k	322	15	and	and	CC
cord-263699-gosqpg3k	322	16	protein	protein	NN
cord-263699-gosqpg3k	322	17	trafficking	traffic	VBG
cord-263699-gosqpg3k	322	18	Distinct	distinct	JJ
cord-263699-gosqpg3k	322	19	functions	function	NNS
cord-263699-gosqpg3k	322	20	for	for	IN
cord-263699-gosqpg3k	322	21	Arf	arf	NN
cord-263699-gosqpg3k	322	22	guanine	guanine	NN
cord-263699-gosqpg3k	322	23	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	322	24	exchange	exchange	NN
cord-263699-gosqpg3k	322	25	factors	factor	NNS
cord-263699-gosqpg3k	322	26	at	at	IN
cord-263699-gosqpg3k	322	27	the	the	DT
cord-263699-gosqpg3k	322	28	Golgi	Golgi	NNP
cord-263699-gosqpg3k	322	29	complex	complex	NN
cord-263699-gosqpg3k	322	30	:	:	:
cord-263699-gosqpg3k	323	1	GBF1	GBF1	NNP
cord-263699-gosqpg3k	323	2	and	and	CC
cord-263699-gosqpg3k	323	3	BIGs	BIGs	NNP
cord-263699-gosqpg3k	323	4	are	be	VBP
cord-263699-gosqpg3k	323	5	required	require	VBN
cord-263699-gosqpg3k	323	6	for	for	IN
cord-263699-gosqpg3k	323	7	assembly	assembly	NN
cord-263699-gosqpg3k	323	8	and	and	CC
cord-263699-gosqpg3k	323	9	maintenance	maintenance	NN
cord-263699-gosqpg3k	323	10	of	of	IN
cord-263699-gosqpg3k	323	11	the	the	DT
cord-263699-gosqpg3k	323	12	Golgi	Golgi	NNP
cord-263699-gosqpg3k	323	13	Stack	Stack	NNP
cord-263699-gosqpg3k	323	14	and	and	CC
cord-263699-gosqpg3k	323	15	Trans	Trans	NNP
cord-263699-gosqpg3k	323	16	-	-	NNP
cord-263699-gosqpg3k	323	17	Golgi	Golgi	NNP
cord-263699-gosqpg3k	323	18	network	network	NN
cord-263699-gosqpg3k	323	19	,	,	,
cord-263699-gosqpg3k	324	1	Respectively	respectively	RB
cord-263699-gosqpg3k	324	2	Retrograde	retrograde	JJ
cord-263699-gosqpg3k	324	3	traffic	traffic	NN
cord-263699-gosqpg3k	324	4	from	from	IN
cord-263699-gosqpg3k	324	5	the	the	DT
cord-263699-gosqpg3k	324	6	Golgi	Golgi	NNP
cord-263699-gosqpg3k	324	7	to	to	IN
cord-263699-gosqpg3k	324	8	the	the	DT
cord-263699-gosqpg3k	324	9	endoplasmic	endoplasmic	NN
cord-263699-gosqpg3k	324	10	reticulum	reticulum	NN
cord-263699-gosqpg3k	324	11	Specific	specific	JJ
cord-263699-gosqpg3k	324	12	functions	function	NNS
cord-263699-gosqpg3k	324	13	of	of	IN
cord-263699-gosqpg3k	324	14	BIG1	BIG1	NNP
cord-263699-gosqpg3k	324	15	and	and	CC
cord-263699-gosqpg3k	324	16	BIG2	BIG2	NNP
cord-263699-gosqpg3k	324	17	in	in	IN
cord-263699-gosqpg3k	324	18	endomembrane	endomembrane	NNP
cord-263699-gosqpg3k	324	19	organization	organization	NN
cord-263699-gosqpg3k	324	20	Maintenance	Maintenance	NNP
cord-263699-gosqpg3k	324	21	of	of	IN
cord-263699-gosqpg3k	324	22	Golgi	Golgi	NNP
cord-263699-gosqpg3k	324	23	structure	structure	NN
cord-263699-gosqpg3k	324	24	and	and	CC
cord-263699-gosqpg3k	324	25	function	function	NN
cord-263699-gosqpg3k	324	26	depends	depend	VBZ
cord-263699-gosqpg3k	324	27	on	on	IN
cord-263699-gosqpg3k	324	28	the	the	DT
cord-263699-gosqpg3k	324	29	integrity	integrity	NN
cord-263699-gosqpg3k	324	30	of	of	IN
cord-263699-gosqpg3k	324	31	ER	ER	NNP
cord-263699-gosqpg3k	324	32	export	export	NN
cord-263699-gosqpg3k	324	33	Organelle	Organelle	NNP
cord-263699-gosqpg3k	324	34	biogenesis	biogenesis	NN
cord-263699-gosqpg3k	324	35	in	in	IN
cord-263699-gosqpg3k	324	36	the	the	DT
cord-263699-gosqpg3k	324	37	endoplasmic	endoplasmic	NN
cord-263699-gosqpg3k	324	38	reticulum	reticulum	NN
cord-263699-gosqpg3k	324	39	Primer	Primer	NNP
cord-263699-gosqpg3k	324	40	on	on	IN
cord-263699-gosqpg3k	324	41	vesicle	vesicle	NN
cord-263699-gosqpg3k	324	42	budding	bud	VBG
cord-263699-gosqpg3k	324	43	Coat	Coat	NNP
cord-263699-gosqpg3k	324	44	proteins	protein	NNS
cord-263699-gosqpg3k	324	45	and	and	CC
cord-263699-gosqpg3k	324	46	vesicle	vesicle	NN
cord-263699-gosqpg3k	324	47	budding	bud	VBG
cord-263699-gosqpg3k	324	48	Protein	Protein	NNP
cord-263699-gosqpg3k	324	49	sorting	sorting	NN
cord-263699-gosqpg3k	324	50	by	by	IN
cord-263699-gosqpg3k	324	51	transport	transport	NN
cord-263699-gosqpg3k	324	52	vesicles	vesicle	NNS
cord-263699-gosqpg3k	324	53	Three	three	CD
cord-263699-gosqpg3k	324	54	ways	way	NNS
cord-263699-gosqpg3k	324	55	to	to	TO
cord-263699-gosqpg3k	324	56	make	make	VB
cord-263699-gosqpg3k	324	57	a	a	DT
cord-263699-gosqpg3k	324	58	vesicle	vesicle	NN
cord-263699-gosqpg3k	324	59	Mechanisms	Mechanisms	NNPS
cord-263699-gosqpg3k	324	60	of	of	IN
cord-263699-gosqpg3k	324	61	vesicle	vesicle	NN
cord-263699-gosqpg3k	324	62	formation	formation	NN
cord-263699-gosqpg3k	324	63	:	:	:
cord-263699-gosqpg3k	325	1	Insights	insight	NNS
cord-263699-gosqpg3k	325	2	from	from	IN
cord-263699-gosqpg3k	325	3	the	the	DT
cord-263699-gosqpg3k	325	4	COP	cop	NN
cord-263699-gosqpg3k	325	5	system	system	NN
cord-263699-gosqpg3k	325	6	COPII	COPII	NNP
cord-263699-gosqpg3k	325	7	:	:	:
cord-263699-gosqpg3k	326	1	A	a	DT
cord-263699-gosqpg3k	326	2	membrane	membrane	NN
cord-263699-gosqpg3k	326	3	coat	coat	NN
cord-263699-gosqpg3k	326	4	formed	form	VBN
cord-263699-gosqpg3k	326	5	by	by	IN
cord-263699-gosqpg3k	326	6	set	set	NN
cord-263699-gosqpg3k	326	7	proteins	protein	NNS
cord-263699-gosqpg3k	326	8	that	that	WDT
cord-263699-gosqpg3k	326	9	drive	drive	VBP
cord-263699-gosqpg3k	326	10	vesicle	vesicle	NN
cord-263699-gosqpg3k	326	11	budding	bud	VBG
cord-263699-gosqpg3k	326	12	from	from	IN
cord-263699-gosqpg3k	326	13	the	the	DT
cord-263699-gosqpg3k	326	14	endoplasmic	endoplasmic	NN
cord-263699-gosqpg3k	326	15	reticulum	reticulum	NN
cord-263699-gosqpg3k	326	16	Bi	bi	JJ
cord-263699-gosqpg3k	326	17	-	-	HYPH
cord-263699-gosqpg3k	326	18	directional	directional	JJ
cord-263699-gosqpg3k	326	19	protein	protein	NN
cord-263699-gosqpg3k	326	20	transport	transport	NN
cord-263699-gosqpg3k	326	21	between	between	IN
cord-263699-gosqpg3k	326	22	the	the	DT
cord-263699-gosqpg3k	326	23	ER	ER	NNP
cord-263699-gosqpg3k	326	24	and	and	CC
cord-263699-gosqpg3k	326	25	Golgi	Golgi	NNP
cord-263699-gosqpg3k	326	26	COPI	COPI	NNP
cord-263699-gosqpg3k	326	27	budding	bud	VBG
cord-263699-gosqpg3k	326	28	within	within	IN
cord-263699-gosqpg3k	326	29	the	the	DT
cord-263699-gosqpg3k	326	30	Golgi	Golgi	NNP
cord-263699-gosqpg3k	326	31	stack	stack	NN
cord-263699-gosqpg3k	326	32	Immunocytochemical	Immunocytochemical	NNP
cord-263699-gosqpg3k	326	33	localization	localization	NN
cord-263699-gosqpg3k	326	34	of	of	IN
cord-263699-gosqpg3k	326	35	beta	beta	NN
cord-263699-gosqpg3k	326	36	-	-	HYPH
cord-263699-gosqpg3k	326	37	COP	cop	NN
cord-263699-gosqpg3k	326	38	to	to	IN
cord-263699-gosqpg3k	326	39	the	the	DT
cord-263699-gosqpg3k	326	40	ER	ER	NNP
cord-263699-gosqpg3k	326	41	-	-	HYPH
cord-263699-gosqpg3k	326	42	Golgi	Golgi	NNP
cord-263699-gosqpg3k	326	43	boundary	boundary	NN
cord-263699-gosqpg3k	326	44	and	and	CC
cord-263699-gosqpg3k	326	45	the	the	DT
cord-263699-gosqpg3k	326	46	TGN	TGN	NNP
cord-263699-gosqpg3k	326	47	Beta	Beta	NNP
cord-263699-gosqpg3k	326	48	-	-	HYPH
cord-263699-gosqpg3k	326	49	COP	COP	NNP
cord-263699-gosqpg3k	326	50	,	,	,
cord-263699-gosqpg3k	326	51	a	a	DT
cord-263699-gosqpg3k	326	52	110	110	CD
cord-263699-gosqpg3k	326	53	kd	kd	NNP
cord-263699-gosqpg3k	326	54	protein	protein	NN
cord-263699-gosqpg3k	326	55	associated	associate	VBN
cord-263699-gosqpg3k	326	56	with	with	IN
cord-263699-gosqpg3k	326	57	non	non	JJ
cord-263699-gosqpg3k	326	58	-	-	JJ
cord-263699-gosqpg3k	326	59	clathrin	clathrin	JJ
cord-263699-gosqpg3k	326	60	-	-	HYPH
cord-263699-gosqpg3k	326	61	coated	coat	VBN
cord-263699-gosqpg3k	326	62	vesicles	vesicle	NNS
cord-263699-gosqpg3k	326	63	and	and	CC
cord-263699-gosqpg3k	326	64	the	the	DT
cord-263699-gosqpg3k	326	65	Golgi	Golgi	NNP
cord-263699-gosqpg3k	326	66	complex	complex	NN
cord-263699-gosqpg3k	326	67	,	,	,
cord-263699-gosqpg3k	326	68	shows	show	VBZ
cord-263699-gosqpg3k	326	69	homology	homology	NN
cord-263699-gosqpg3k	326	70	to	to	IN
cord-263699-gosqpg3k	326	71	beta	beta	NN
cord-263699-gosqpg3k	326	72	-	-	HYPH
cord-263699-gosqpg3k	326	73	adaptin	adaptin	NNP
cord-263699-gosqpg3k	326	74	Clathrin	Clathrin	NNP
cord-263699-gosqpg3k	326	75	-	-	HYPH
cord-263699-gosqpg3k	326	76	mediated	mediate	VBN
cord-263699-gosqpg3k	326	77	transport	transport	NN
cord-263699-gosqpg3k	326	78	:	:	:
cord-263699-gosqpg3k	326	79	Assembly	assembly	NN
cord-263699-gosqpg3k	326	80	required	require	VBN
cord-263699-gosqpg3k	326	81	.	.	.
cord-263699-gosqpg3k	327	1	Workshop	workshop	NN
cord-263699-gosqpg3k	327	2	on	on	IN
cord-263699-gosqpg3k	327	3	molecular	molecular	JJ
cord-263699-gosqpg3k	327	4	mechanisms	mechanism	NNS
cord-263699-gosqpg3k	327	5	of	of	IN
cord-263699-gosqpg3k	327	6	vesicle	vesicle	NN
cord-263699-gosqpg3k	327	7	selectivity	selectivity	NN
cord-263699-gosqpg3k	327	8	Functional	functional	JJ
cord-263699-gosqpg3k	327	9	dissection	dissection	NN
cord-263699-gosqpg3k	327	10	of	of	IN
cord-263699-gosqpg3k	327	11	COP	cop	NN
cord-263699-gosqpg3k	327	12	-	-	:
cord-263699-gosqpg3k	327	13	I	-PRON-	PRP
cord-263699-gosqpg3k	327	14	Subunits	subunits	VBP
cord-263699-gosqpg3k	327	15	in	in	IN
cord-263699-gosqpg3k	327	16	the	the	DT
cord-263699-gosqpg3k	327	17	biogenesis	biogenesis	NN
cord-263699-gosqpg3k	327	18	of	of	IN
cord-263699-gosqpg3k	327	19	multivesicular	multivesicular	NNP
cord-263699-gosqpg3k	327	20	endosomes	endosome	VBZ
cord-263699-gosqpg3k	327	21	Inhibition	Inhibition	NNP
cord-263699-gosqpg3k	327	22	of	of	IN
cord-263699-gosqpg3k	327	23	endosome	endosome	NN
cord-263699-gosqpg3k	327	24	function	function	NN
cord-263699-gosqpg3k	327	25	in	in	IN
cord-263699-gosqpg3k	327	26	CHO	CHO	NNP
cord-263699-gosqpg3k	327	27	Cells	Cells	NNP
cord-263699-gosqpg3k	327	28	bearing	bear	VBG
cord-263699-gosqpg3k	327	29	a	a	DT
cord-263699-gosqpg3k	327	30	temperature	temperature	NN
cord-263699-gosqpg3k	327	31	-	-	HYPH
cord-263699-gosqpg3k	327	32	sensitive	sensitive	JJ
cord-263699-gosqpg3k	327	33	defect	defect	NN
cord-263699-gosqpg3k	327	34	in	in	IN
cord-263699-gosqpg3k	327	35	the	the	DT
cord-263699-gosqpg3k	327	36	Coatomer	Coatomer	NNP
cord-263699-gosqpg3k	327	37	(	(	-LRB-
cord-263699-gosqpg3k	327	38	COPI	COPI	NNP
cord-263699-gosqpg3k	327	39	)	)	-RRB-
cord-263699-gosqpg3k	327	40	component	component	NN
cord-263699-gosqpg3k	327	41	-	-	HYPH
cord-263699-gosqpg3k	327	42	COP	cop	NN
cord-263699-gosqpg3k	327	43	Role	role	NN
cord-263699-gosqpg3k	327	44	of	of	IN
cord-263699-gosqpg3k	327	45	COPI	COPI	NNP
cord-263699-gosqpg3k	327	46	in	in	IN
cord-263699-gosqpg3k	327	47	phagosome	phagosome	NN
cord-263699-gosqpg3k	327	48	maturation	maturation	NN
cord-263699-gosqpg3k	328	1	Early	early	JJ
cord-263699-gosqpg3k	328	2	endosomes	endosome	NNS
cord-263699-gosqpg3k	328	3	and	and	CC
cord-263699-gosqpg3k	328	4	endosomal	endosomal	NNP
cord-263699-gosqpg3k	328	5	coatomer	coatomer	NNP
cord-263699-gosqpg3k	328	6	are	be	VBP
cord-263699-gosqpg3k	328	7	required	require	VBN
cord-263699-gosqpg3k	328	8	for	for	IN
cord-263699-gosqpg3k	328	9	autophagy	autophagy	NN
cord-263699-gosqpg3k	328	10	Peroxisome	Peroxisome	NNP
cord-263699-gosqpg3k	328	11	biogenesis	biogenesis	NN
cord-263699-gosqpg3k	328	12	:	:	:
cord-263699-gosqpg3k	328	13	Where	where	WRB
cord-263699-gosqpg3k	328	14	Arf	Arf	NNP
cord-263699-gosqpg3k	328	15	and	and	CC
cord-263699-gosqpg3k	328	16	coatomer	coatomer	NN
cord-263699-gosqpg3k	328	17	might	may	MD
cord-263699-gosqpg3k	328	18	be	be	VB
cord-263699-gosqpg3k	328	19	involved	involve	VBN
cord-263699-gosqpg3k	328	20	COPI	COPI	NNP
cord-263699-gosqpg3k	328	21	complex	complex	JJ
cord-263699-gosqpg3k	328	22	is	be	VBZ
cord-263699-gosqpg3k	328	23	a	a	DT
cord-263699-gosqpg3k	328	24	regulator	regulator	NN
cord-263699-gosqpg3k	328	25	of	of	IN
cord-263699-gosqpg3k	328	26	lipid	lipid	NN
cord-263699-gosqpg3k	328	27	homeostasis	homeostasis	NN
cord-263699-gosqpg3k	328	28	Functional	functional	JJ
cord-263699-gosqpg3k	328	29	genomic	genomic	JJ
cord-263699-gosqpg3k	328	30	screen	screen	NN
cord-263699-gosqpg3k	328	31	reveals	reveal	VBZ
cord-263699-gosqpg3k	328	32	genes	gene	NNS
cord-263699-gosqpg3k	328	33	involved	involve	VBN
cord-263699-gosqpg3k	328	34	in	in	IN
cord-263699-gosqpg3k	328	35	lipid	lipid	NN
cord-263699-gosqpg3k	328	36	-	-	HYPH
cord-263699-gosqpg3k	328	37	droplet	droplet	NN
cord-263699-gosqpg3k	328	38	formation	formation	NN
cord-263699-gosqpg3k	328	39	and	and	CC
cord-263699-gosqpg3k	328	40	utilization	utilization	NN
cord-263699-gosqpg3k	328	41	Arf	Arf	NNP
cord-263699-gosqpg3k	328	42	family	family	NN
cord-263699-gosqpg3k	328	43	G	g	NN
cord-263699-gosqpg3k	328	44	proteins	protein	NNS
cord-263699-gosqpg3k	328	45	and	and	CC
cord-263699-gosqpg3k	328	46	their	-PRON-	PRP$
cord-263699-gosqpg3k	328	47	regulators	regulator	NNS
cord-263699-gosqpg3k	328	48	:	:	:
cord-263699-gosqpg3k	328	49	Roles	role	NNS
cord-263699-gosqpg3k	328	50	in	in	IN
cord-263699-gosqpg3k	328	51	membrane	membrane	NN
cord-263699-gosqpg3k	328	52	transport	transport	NN
cord-263699-gosqpg3k	328	53	,	,	,
cord-263699-gosqpg3k	328	54	development	development	NN
cord-263699-gosqpg3k	328	55	and	and	CC
cord-263699-gosqpg3k	328	56	disease	disease	NN
cord-263699-gosqpg3k	328	57	Nomenclature	nomenclature	NN
cord-263699-gosqpg3k	328	58	for	for	IN
cord-263699-gosqpg3k	328	59	the	the	DT
cord-263699-gosqpg3k	328	60	human	human	JJ
cord-263699-gosqpg3k	328	61	Arf	Arf	NNP
cord-263699-gosqpg3k	328	62	family	family	NN
cord-263699-gosqpg3k	328	63	of	of	IN
cord-263699-gosqpg3k	328	64	GTP	gtp	NN
cord-263699-gosqpg3k	328	65	-	-	HYPH
cord-263699-gosqpg3k	328	66	binding	bind	VBG
cord-263699-gosqpg3k	328	67	proteins	protein	NNS
cord-263699-gosqpg3k	328	68	:	:	:
cord-263699-gosqpg3k	328	69	Arf	Arf	NNP
cord-263699-gosqpg3k	328	70	,	,	,
cord-263699-gosqpg3k	328	71	ARL	ARL	NNP
cord-263699-gosqpg3k	328	72	,	,	,
cord-263699-gosqpg3k	328	73	and	and	CC
cord-263699-gosqpg3k	328	74	SAR	SAR	NNP
cord-263699-gosqpg3k	328	75	proteins	protein	NNS
cord-263699-gosqpg3k	328	76	Toward	toward	IN
cord-263699-gosqpg3k	328	77	a	a	DT
cord-263699-gosqpg3k	328	78	structural	structural	JJ
cord-263699-gosqpg3k	328	79	understanding	understanding	NN
cord-263699-gosqpg3k	328	80	of	of	IN
cord-263699-gosqpg3k	328	81	Arf	Arf	NNP
cord-263699-gosqpg3k	328	82	family	family	NN
cord-263699-gosqpg3k	328	83	:	:	:
cord-263699-gosqpg3k	329	1	Effector	effector	NN
cord-263699-gosqpg3k	329	2	specificity	specificity	NN
cord-263699-gosqpg3k	329	3	.	.	.
cord-263699-gosqpg3k	330	1	Structure	Structure	NNP
cord-263699-gosqpg3k	330	2	Isoform	Isoform	NNP
cord-263699-gosqpg3k	330	3	-	-	HYPH
cord-263699-gosqpg3k	330	4	selective	selective	JJ
cord-263699-gosqpg3k	330	5	effects	effect	NNS
cord-263699-gosqpg3k	330	6	of	of	IN
cord-263699-gosqpg3k	330	7	the	the	DT
cord-263699-gosqpg3k	330	8	depletion	depletion	NN
cord-263699-gosqpg3k	330	9	of	of	IN
cord-263699-gosqpg3k	330	10	ADPribosylation	adpribosylation	NN
cord-263699-gosqpg3k	330	11	factors	factor	NNS
cord-263699-gosqpg3k	330	12	1	1	CD
cord-263699-gosqpg3k	330	13	-	-	SYM
cord-263699-gosqpg3k	330	14	5	5	CD
cord-263699-gosqpg3k	330	15	on	on	IN
cord-263699-gosqpg3k	330	16	membrane	membrane	NN
cord-263699-gosqpg3k	330	17	traffic	traffic	NN
cord-263699-gosqpg3k	330	18	N	n	CD
cord-263699-gosqpg3k	330	19	-	-	HYPH
cord-263699-gosqpg3k	330	20	terminal	terminal	JJ
cord-263699-gosqpg3k	330	21	hydrophobic	hydrophobic	JJ
cord-263699-gosqpg3k	330	22	residues	residue	NNS
cord-263699-gosqpg3k	330	23	of	of	IN
cord-263699-gosqpg3k	330	24	the	the	DT
cord-263699-gosqpg3k	330	25	G	g	NN
cord-263699-gosqpg3k	330	26	-	-	HYPH
cord-263699-gosqpg3k	330	27	protein	protein	NN
cord-263699-gosqpg3k	330	28	ADP	ADP	NNP
cord-263699-gosqpg3k	330	29	-	-	HYPH
cord-263699-gosqpg3k	330	30	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	330	31	factor-1	factor-1	NNP
cord-263699-gosqpg3k	330	32	insert	insert	VB
cord-263699-gosqpg3k	330	33	into	into	IN
cord-263699-gosqpg3k	330	34	membrane	membrane	NN
cord-263699-gosqpg3k	330	35	phospholipids	phospholipid	NNS
cord-263699-gosqpg3k	330	36	upon	upon	IN
cord-263699-gosqpg3k	330	37	GDP	GDP	NNP
cord-263699-gosqpg3k	330	38	to	to	IN
cord-263699-gosqpg3k	330	39	GTP	GTP	NNP
cord-263699-gosqpg3k	330	40	exchange	exchange	NN
cord-263699-gosqpg3k	330	41	Mechanisms	Mechanisms	NNPS
cord-263699-gosqpg3k	330	42	of	of	IN
cord-263699-gosqpg3k	330	43	COPI	COPI	NNP
cord-263699-gosqpg3k	330	44	vesicle	vesicle	NN
cord-263699-gosqpg3k	330	45	formation	formation	NN
cord-263699-gosqpg3k	331	1	The	the	DT
cord-263699-gosqpg3k	331	2	COPI	COPI	NNP
cord-263699-gosqpg3k	331	3	system	system	NN
cord-263699-gosqpg3k	331	4	:	:	:
cord-263699-gosqpg3k	331	5	Molecular	molecular	JJ
cord-263699-gosqpg3k	331	6	mechanisms	mechanism	NNS
cord-263699-gosqpg3k	331	7	and	and	CC
cord-263699-gosqpg3k	331	8	function	function	VB
cord-263699-gosqpg3k	331	9	GBF1	GBF1	NNP
cord-263699-gosqpg3k	331	10	and	and	CC
cord-263699-gosqpg3k	331	11	Arf1	Arf1	NNP
cord-263699-gosqpg3k	331	12	function	function	NN
cord-263699-gosqpg3k	331	13	in	in	IN
cord-263699-gosqpg3k	331	14	vesicular	vesicular	JJ
cord-263699-gosqpg3k	331	15	trafficking	trafficking	NN
cord-263699-gosqpg3k	331	16	,	,	,
cord-263699-gosqpg3k	331	17	lipid	lipid	NN
cord-263699-gosqpg3k	331	18	homoeostasis	homoeostasis	NN
cord-263699-gosqpg3k	331	19	and	and	CC
cord-263699-gosqpg3k	331	20	organelle	organelle	NN
cord-263699-gosqpg3k	331	21	dynamics	dynamic	NNS
cord-263699-gosqpg3k	331	22	Targeting	target	VBG
cord-263699-gosqpg3k	331	23	of	of	IN
cord-263699-gosqpg3k	331	24	the	the	DT
cord-263699-gosqpg3k	331	25	Arf	Arf	NNP
cord-263699-gosqpg3k	331	26	-	-	HYPH
cord-263699-gosqpg3k	331	27	GEF	GEF	NNP
cord-263699-gosqpg3k	331	28	GBF1	GBF1	NNP
cord-263699-gosqpg3k	331	29	to	to	IN
cord-263699-gosqpg3k	331	30	lipid	lipid	NN
cord-263699-gosqpg3k	331	31	droplets	droplet	NNS
cord-263699-gosqpg3k	331	32	and	and	CC
cord-263699-gosqpg3k	331	33	Golgi	Golgi	NNP
cord-263699-gosqpg3k	331	34	membranes	membrane	NNS
cord-263699-gosqpg3k	331	35	Crystal	Crystal	NNP
cord-263699-gosqpg3k	331	36	structure	structure	NN
cord-263699-gosqpg3k	331	37	of	of	IN
cord-263699-gosqpg3k	331	38	Arf1*Sec7	arf1*sec7	XX
cord-263699-gosqpg3k	332	1	complexed	complexe	VBN
cord-263699-gosqpg3k	332	2	with	with	IN
cord-263699-gosqpg3k	332	3	brefeldin	brefeldin	NNP
cord-263699-gosqpg3k	332	4	A	A	NNP
cord-263699-gosqpg3k	332	5	and	and	CC
cord-263699-gosqpg3k	332	6	its	-PRON-	PRP$
cord-263699-gosqpg3k	332	7	implications	implication	NNS
cord-263699-gosqpg3k	332	8	for	for	IN
cord-263699-gosqpg3k	332	9	the	the	DT
cord-263699-gosqpg3k	332	10	guanine	guanine	NN
cord-263699-gosqpg3k	332	11	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	332	12	exchange	exchange	NN
cord-263699-gosqpg3k	332	13	mechanism	mechanism	NN
cord-263699-gosqpg3k	332	14	Structural	structural	JJ
cord-263699-gosqpg3k	332	15	basis	basis	NN
cord-263699-gosqpg3k	332	16	for	for	IN
cord-263699-gosqpg3k	332	17	activation	activation	NN
cord-263699-gosqpg3k	332	18	of	of	IN
cord-263699-gosqpg3k	332	19	Arf	Arf	NNP
cord-263699-gosqpg3k	332	20	GTPase	GTPase	NNP
cord-263699-gosqpg3k	332	21	:	:	:
cord-263699-gosqpg3k	333	1	Mechanisms	mechanism	NNS
cord-263699-gosqpg3k	333	2	of	of	IN
cord-263699-gosqpg3k	333	3	guanine	guanine	NN
cord-263699-gosqpg3k	333	4	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	333	5	exchange	exchange	NN
cord-263699-gosqpg3k	333	6	and	and	CC
cord-263699-gosqpg3k	333	7	GTP	GTP	NNP
cord-263699-gosqpg3k	333	8	-	-	HYPH
cord-263699-gosqpg3k	333	9	myristoyl	myristoyl	NNP
cord-263699-gosqpg3k	333	10	switching	switch	VBG
cord-263699-gosqpg3k	333	11	GBF1	GBF1	NNP
cord-263699-gosqpg3k	333	12	:	:	:
cord-263699-gosqpg3k	334	1	A	a	DT
cord-263699-gosqpg3k	334	2	Novel	Novel	NNP
cord-263699-gosqpg3k	334	3	Golgi	golgi	NN
cord-263699-gosqpg3k	334	4	-	-	HYPH
cord-263699-gosqpg3k	334	5	associated	associate	VBN
cord-263699-gosqpg3k	334	6	BFA	BFA	NNP
cord-263699-gosqpg3k	334	7	-	-	HYPH
cord-263699-gosqpg3k	334	8	resistant	resistant	JJ
cord-263699-gosqpg3k	334	9	Guanine	Guanine	NNP
cord-263699-gosqpg3k	334	10	Nucleotide	Nucleotide	NNP
cord-263699-gosqpg3k	334	11	Exchange	Exchange	NNP
cord-263699-gosqpg3k	334	12	Factor	Factor	NNP
cord-263699-gosqpg3k	335	1	That	that	DT
cord-263699-gosqpg3k	335	2	displays	display	VBZ
cord-263699-gosqpg3k	335	3	specificity	specificity	NN
cord-263699-gosqpg3k	335	4	for	for	IN
cord-263699-gosqpg3k	335	5	ADP	adp	NN
cord-263699-gosqpg3k	335	6	-	-	HYPH
cord-263699-gosqpg3k	335	7	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	335	8	factor	factor	NN
cord-263699-gosqpg3k	335	9	5	5	CD
cord-263699-gosqpg3k	335	10	Dynamics	dynamic	NNS
cord-263699-gosqpg3k	335	11	of	of	IN
cord-263699-gosqpg3k	335	12	GBF1	GBF1	NNP
cord-263699-gosqpg3k	335	13	,	,	,
cord-263699-gosqpg3k	335	14	a	a	DT
cord-263699-gosqpg3k	335	15	brefeldin	brefeldin	NNP
cord-263699-gosqpg3k	335	16	A	A	NNP
cord-263699-gosqpg3k	335	17	-	-	HYPH
cord-263699-gosqpg3k	335	18	sensitive	sensitive	JJ
cord-263699-gosqpg3k	335	19	Arf1	Arf1	NNP
cord-263699-gosqpg3k	335	20	Exchange	Exchange	NNP
cord-263699-gosqpg3k	335	21	Factor	Factor	NNP
cord-263699-gosqpg3k	335	22	at	at	IN
cord-263699-gosqpg3k	335	23	the	the	DT
cord-263699-gosqpg3k	335	24	Golgi	Golgi	NNP
cord-263699-gosqpg3k	335	25	Dissection	dissection	NN
cord-263699-gosqpg3k	335	26	of	of	IN
cord-263699-gosqpg3k	335	27	membrane	membrane	NN
cord-263699-gosqpg3k	335	28	dynamics	dynamic	NNS
cord-263699-gosqpg3k	335	29	of	of	IN
cord-263699-gosqpg3k	335	30	the	the	DT
cord-263699-gosqpg3k	335	31	Arf	Arf	NNP
cord-263699-gosqpg3k	335	32	-	-	HYPH
cord-263699-gosqpg3k	335	33	guanine	guanine	NN
cord-263699-gosqpg3k	335	34	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	335	35	exchange	exchange	NN
cord-263699-gosqpg3k	335	36	factor	factor	NN
cord-263699-gosqpg3k	335	37	GBF1	GBF1	NNP
cord-263699-gosqpg3k	335	38	Large	Large	NNP
cord-263699-gosqpg3k	335	39	Arf	Arf	NNP
cord-263699-gosqpg3k	335	40	guanine	guanine	NN
cord-263699-gosqpg3k	335	41	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	335	42	exchange	exchange	NN
cord-263699-gosqpg3k	335	43	factors	factor	NNS
cord-263699-gosqpg3k	335	44	in	in	IN
cord-263699-gosqpg3k	335	45	membrane	membrane	NN
cord-263699-gosqpg3k	335	46	trafficking	traffic	VBG
cord-263699-gosqpg3k	335	47	Interaction	interaction	NN
cord-263699-gosqpg3k	335	48	between	between	IN
cord-263699-gosqpg3k	335	49	the	the	DT
cord-263699-gosqpg3k	335	50	triglyceride	triglyceride	NN
cord-263699-gosqpg3k	335	51	lipase	lipase	NN
cord-263699-gosqpg3k	335	52	ATGL	ATGL	NNP
cord-263699-gosqpg3k	335	53	and	and	CC
cord-263699-gosqpg3k	335	54	the	the	DT
cord-263699-gosqpg3k	335	55	Arf1	Arf1	NNP
cord-263699-gosqpg3k	335	56	activator	activator	NN
cord-263699-gosqpg3k	335	57	GBF1	GBF1	NNP
cord-263699-gosqpg3k	336	1	The	the	DT
cord-263699-gosqpg3k	336	2	Arf	Arf	NNP
cord-263699-gosqpg3k	336	3	guanine	guanine	NN
cord-263699-gosqpg3k	336	4	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	336	5	exchange	exchange	NN
cord-263699-gosqpg3k	336	6	factor	factor	NN
cord-263699-gosqpg3k	336	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	336	8	is	be	VBZ
cord-263699-gosqpg3k	336	9	targeted	target	VBN
cord-263699-gosqpg3k	336	10	to	to	IN
cord-263699-gosqpg3k	336	11	Golgi	Golgi	NNP
cord-263699-gosqpg3k	336	12	membranes	membrane	NNS
cord-263699-gosqpg3k	336	13	through	through	IN
cord-263699-gosqpg3k	336	14	a	a	DT
cord-263699-gosqpg3k	336	15	PIP	PIP	NNP
cord-263699-gosqpg3k	336	16	-	-	HYPH
cord-263699-gosqpg3k	336	17	binding	bind	VBG
cord-263699-gosqpg3k	336	18	domain	domain	NN
cord-263699-gosqpg3k	336	19	Impairment	impairment	NN
cord-263699-gosqpg3k	336	20	of	of	IN
cord-263699-gosqpg3k	336	21	cargo	cargo	NN
cord-263699-gosqpg3k	336	22	transportation	transportation	NN
cord-263699-gosqpg3k	336	23	caused	cause	VBN
cord-263699-gosqpg3k	336	24	by	by	IN
cord-263699-gosqpg3k	336	25	GBF1	GBF1	NNP
cord-263699-gosqpg3k	336	26	mutation	mutation	NN
cord-263699-gosqpg3k	336	27	disrupts	disrupt	VBZ
cord-263699-gosqpg3k	336	28	vascular	vascular	JJ
cord-263699-gosqpg3k	336	29	integrity	integrity	NN
cord-263699-gosqpg3k	336	30	and	and	CC
cord-263699-gosqpg3k	336	31	causes	cause	VBZ
cord-263699-gosqpg3k	336	32	hemorrhage	hemorrhage	NN
cord-263699-gosqpg3k	336	33	in	in	IN
cord-263699-gosqpg3k	336	34	zebrafish	zebrafish	NN
cord-263699-gosqpg3k	336	35	embryos	embryo	NNS
cord-263699-gosqpg3k	336	36	Chlamydia	Chlamydia	NNP
cord-263699-gosqpg3k	336	37	trachomatis	trachomatis	NN
cord-263699-gosqpg3k	336	38	hijacks	hijack	VBZ
cord-263699-gosqpg3k	336	39	intra	intra	JJ
cord-263699-gosqpg3k	336	40	-	-	JJ
cord-263699-gosqpg3k	336	41	Golgi	golgi	JJ
cord-263699-gosqpg3k	336	42	COG	cog	NN
cord-263699-gosqpg3k	336	43	complex	complex	JJ
cord-263699-gosqpg3k	336	44	-	-	HYPH
cord-263699-gosqpg3k	336	45	dependent	dependent	JJ
cord-263699-gosqpg3k	336	46	vesicle	vesicle	NN
cord-263699-gosqpg3k	336	47	trafficking	traffic	VBG
cord-263699-gosqpg3k	336	48	pathway	pathway	NN
cord-263699-gosqpg3k	336	49	RNAi	RNAi	NNP
cord-263699-gosqpg3k	336	50	screen	screen	NN
cord-263699-gosqpg3k	336	51	of	of	IN
cord-263699-gosqpg3k	336	52	Salmonella	Salmonella	NNP
cord-263699-gosqpg3k	336	53	invasion	invasion	NN
cord-263699-gosqpg3k	336	54	shows	show	VBZ
cord-263699-gosqpg3k	336	55	role	role	NN
cord-263699-gosqpg3k	336	56	of	of	IN
cord-263699-gosqpg3k	336	57	COPI	COPI	NNP
cord-263699-gosqpg3k	336	58	in	in	IN
cord-263699-gosqpg3k	336	59	membrane	membrane	NN
cord-263699-gosqpg3k	336	60	targeting	target	VBG
cord-263699-gosqpg3k	336	61	of	of	IN
cord-263699-gosqpg3k	336	62	cholesterol	cholesterol	NN
cord-263699-gosqpg3k	336	63	and	and	CC
cord-263699-gosqpg3k	336	64	Cdc42	Cdc42	NNP
cord-263699-gosqpg3k	337	1	Golgicide	Golgicide	NNP
cord-263699-gosqpg3k	337	2	A	a	DT
cord-263699-gosqpg3k	337	3	reveals	reveal	VBZ
cord-263699-gosqpg3k	337	4	essential	essential	JJ
cord-263699-gosqpg3k	337	5	roles	role	NNS
cord-263699-gosqpg3k	337	6	for	for	IN
cord-263699-gosqpg3k	337	7	GBF1	GBF1	NNP
cord-263699-gosqpg3k	337	8	in	in	IN
cord-263699-gosqpg3k	337	9	Golgi	Golgi	NNP
cord-263699-gosqpg3k	337	10	assembly	assembly	NN
cord-263699-gosqpg3k	337	11	and	and	CC
cord-263699-gosqpg3k	337	12	function	function	VB
cord-263699-gosqpg3k	337	13	Dengue	dengue	NN
cord-263699-gosqpg3k	337	14	virus	virus	NN
cord-263699-gosqpg3k	338	1	uses	use	VBZ
cord-263699-gosqpg3k	338	2	a	a	DT
cord-263699-gosqpg3k	338	3	non	non	JJ
cord-263699-gosqpg3k	338	4	-	-	JJ
cord-263699-gosqpg3k	338	5	canonical	canonical	JJ
cord-263699-gosqpg3k	338	6	function	function	NN
cord-263699-gosqpg3k	338	7	of	of	IN
cord-263699-gosqpg3k	338	8	the	the	DT
cord-263699-gosqpg3k	338	9	host	host	NN
cord-263699-gosqpg3k	338	10	GBF1-Arf	GBF1-Arf	NNP
cord-263699-gosqpg3k	338	11	-	-	HYPH
cord-263699-gosqpg3k	338	12	COPI	COPI	NNP
cord-263699-gosqpg3k	338	13	system	system	NN
cord-263699-gosqpg3k	338	14	for	for	IN
cord-263699-gosqpg3k	338	15	capsid	capsid	NN
cord-263699-gosqpg3k	338	16	protein	protein	NN
cord-263699-gosqpg3k	338	17	accumulation	accumulation	NN
cord-263699-gosqpg3k	338	18	on	on	IN
cord-263699-gosqpg3k	338	19	Lipid	Lipid	NNP
cord-263699-gosqpg3k	338	20	Droplets	Droplets	NNPS
cord-263699-gosqpg3k	339	1	A	a	DT
cord-263699-gosqpg3k	339	2	Global	Global	NNP
cord-263699-gosqpg3k	339	3	Interactome	Interactome	NNP
cord-263699-gosqpg3k	339	4	Map	Map	NNP
cord-263699-gosqpg3k	339	5	of	of	IN
cord-263699-gosqpg3k	339	6	the	the	DT
cord-263699-gosqpg3k	339	7	dengue	dengue	NN
cord-263699-gosqpg3k	339	8	Virus	virus	NN
cord-263699-gosqpg3k	339	9	NS1	ns1	CD
cord-263699-gosqpg3k	339	10	Identifies	identify	VBZ
cord-263699-gosqpg3k	340	1	Virus	Virus	NNP
cord-263699-gosqpg3k	340	2	Restriction	Restriction	NNP
cord-263699-gosqpg3k	340	3	and	and	CC
cord-263699-gosqpg3k	340	4	Dependency	Dependency	NNP
cord-263699-gosqpg3k	340	5	Host	Host	NNP
cord-263699-gosqpg3k	340	6	Factors	Factors	NNP
cord-263699-gosqpg3k	340	7	Viperin	Viperin	NNP
cord-263699-gosqpg3k	340	8	targets	target	VBZ
cord-263699-gosqpg3k	340	9	flavivirus	flavivirus	JJ
cord-263699-gosqpg3k	340	10	virulence	virulence	NN
cord-263699-gosqpg3k	340	11	by	by	IN
cord-263699-gosqpg3k	340	12	inducing	induce	VBG
cord-263699-gosqpg3k	340	13	assembly	assembly	NN
cord-263699-gosqpg3k	340	14	of	of	IN
cord-263699-gosqpg3k	340	15	noninfectious	noninfectious	JJ
cord-263699-gosqpg3k	340	16	capsid	capsid	NN
cord-263699-gosqpg3k	340	17	particles	particle	NNS
cord-263699-gosqpg3k	340	18	Investigation	Investigation	NNP
cord-263699-gosqpg3k	340	19	of	of	IN
cord-263699-gosqpg3k	340	20	the	the	DT
cord-263699-gosqpg3k	340	21	role	role	NN
cord-263699-gosqpg3k	340	22	of	of	IN
cord-263699-gosqpg3k	340	23	GBF1	GBF1	NNP
cord-263699-gosqpg3k	340	24	in	in	IN
cord-263699-gosqpg3k	340	25	the	the	DT
cord-263699-gosqpg3k	340	26	replication	replication	NN
cord-263699-gosqpg3k	340	27	of	of	IN
cord-263699-gosqpg3k	340	28	positive	positive	JJ
cord-263699-gosqpg3k	340	29	-	-	HYPH
cord-263699-gosqpg3k	340	30	sense	sense	NN
cord-263699-gosqpg3k	340	31	single	single	JJ
cord-263699-gosqpg3k	340	32	-	-	HYPH
cord-263699-gosqpg3k	340	33	stranded	strand	VBN
cord-263699-gosqpg3k	340	34	RNA	RNA	NNP
cord-263699-gosqpg3k	340	35	viruses	virus	NNS
cord-263699-gosqpg3k	340	36	Markers	marker	NNS
cord-263699-gosqpg3k	340	37	for	for	IN
cord-263699-gosqpg3k	340	38	trans	trans	NNP
cord-263699-gosqpg3k	340	39	-	-	JJ
cord-263699-gosqpg3k	340	40	Golgi	Golgi	NNP
cord-263699-gosqpg3k	340	41	membranes	membrane	NNS
cord-263699-gosqpg3k	340	42	and	and	CC
cord-263699-gosqpg3k	340	43	the	the	DT
cord-263699-gosqpg3k	340	44	intermediate	intermediate	JJ
cord-263699-gosqpg3k	340	45	compartment	compartment	NN
cord-263699-gosqpg3k	340	46	localize	localize	VBP
cord-263699-gosqpg3k	340	47	to	to	IN
cord-263699-gosqpg3k	340	48	induced	induce	VBN
cord-263699-gosqpg3k	340	49	membranes	membrane	NNS
cord-263699-gosqpg3k	340	50	with	with	IN
cord-263699-gosqpg3k	340	51	distinct	distinct	JJ
cord-263699-gosqpg3k	340	52	replication	replication	NN
cord-263699-gosqpg3k	340	53	functions	function	NNS
cord-263699-gosqpg3k	340	54	in	in	IN
cord-263699-gosqpg3k	340	55	flavivirus	flavivirus	JJ
cord-263699-gosqpg3k	340	56	-	-	HYPH
cord-263699-gosqpg3k	340	57	infected	infect	VBN
cord-263699-gosqpg3k	340	58	cells	cell	NNS
cord-263699-gosqpg3k	341	1	CSFV	CSFV	NNP
cord-263699-gosqpg3k	341	2	proliferation	proliferation	NN
cord-263699-gosqpg3k	341	3	is	be	VBZ
cord-263699-gosqpg3k	341	4	associated	associate	VBN
cord-263699-gosqpg3k	341	5	with	with	IN
cord-263699-gosqpg3k	341	6	GBF1	GBF1	NNP
cord-263699-gosqpg3k	341	7	and	and	CC
cord-263699-gosqpg3k	341	8	Rab2	Rab2	NNP
cord-263699-gosqpg3k	341	9	Identification	Identification	NNP
cord-263699-gosqpg3k	341	10	of	of	IN
cord-263699-gosqpg3k	341	11	GBF1	GBF1	NNP
cord-263699-gosqpg3k	341	12	as	as	IN
cord-263699-gosqpg3k	341	13	a	a	DT
cord-263699-gosqpg3k	341	14	cellular	cellular	JJ
cord-263699-gosqpg3k	341	15	factor	factor	NN
cord-263699-gosqpg3k	341	16	required	require	VBN
cord-263699-gosqpg3k	341	17	for	for	IN
cord-263699-gosqpg3k	341	18	hepatitis	hepatitis	NNP
cord-263699-gosqpg3k	341	19	C	C	NNP
cord-263699-gosqpg3k	341	20	virus	virus	NN
cord-263699-gosqpg3k	341	21	RNA	RNA	NNP
cord-263699-gosqpg3k	341	22	replication	replication	NN
cord-263699-gosqpg3k	342	1	A	a	DT
cord-263699-gosqpg3k	342	2	Functional	functional	JJ
cord-263699-gosqpg3k	342	3	genomic	genomic	JJ
cord-263699-gosqpg3k	342	4	screen	screen	NN
cord-263699-gosqpg3k	342	5	identifies	identify	VBZ
cord-263699-gosqpg3k	342	6	cellular	cellular	JJ
cord-263699-gosqpg3k	342	7	cofactors	cofactor	NNS
cord-263699-gosqpg3k	342	8	of	of	IN
cord-263699-gosqpg3k	342	9	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	342	10	C	c	NN
cord-263699-gosqpg3k	342	11	virus	virus	NN
cord-263699-gosqpg3k	342	12	replication	replication	NN
cord-263699-gosqpg3k	342	13	Arf1	Arf1	NNP
cord-263699-gosqpg3k	342	14	and	and	CC
cord-263699-gosqpg3k	342	15	GBF1	GBF1	NNP
cord-263699-gosqpg3k	342	16	generate	generate	VB
cord-263699-gosqpg3k	342	17	a	a	DT
cord-263699-gosqpg3k	342	18	PI4P	PI4P	VBN
cord-263699-gosqpg3k	342	19	-	-	HYPH
cord-263699-gosqpg3k	342	20	enriched	enrich	VBN
cord-263699-gosqpg3k	342	21	environment	environment	NN
cord-263699-gosqpg3k	342	22	supportive	supportive	JJ
cord-263699-gosqpg3k	342	23	of	of	IN
cord-263699-gosqpg3k	342	24	hepatitis	hepatitis	NNP
cord-263699-gosqpg3k	342	25	C	C	NNP
cord-263699-gosqpg3k	342	26	virus	virus	NN
cord-263699-gosqpg3k	342	27	replication	replication	NN
cord-263699-gosqpg3k	342	28	Involvement	Involvement	NNP
cord-263699-gosqpg3k	342	29	of	of	IN
cord-263699-gosqpg3k	342	30	cellular	cellular	JJ
cord-263699-gosqpg3k	342	31	membrane	membrane	NN
cord-263699-gosqpg3k	342	32	traffic	traffic	NN
cord-263699-gosqpg3k	342	33	proteins	protein	NNS
cord-263699-gosqpg3k	342	34	in	in	IN
cord-263699-gosqpg3k	342	35	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	342	36	replication	replication	NN
cord-263699-gosqpg3k	343	1	A	a	DT
cord-263699-gosqpg3k	343	2	critical	critical	JJ
cord-263699-gosqpg3k	343	3	role	role	NN
cord-263699-gosqpg3k	343	4	of	of	IN
cord-263699-gosqpg3k	343	5	a	a	DT
cord-263699-gosqpg3k	343	6	cellular	cellular	JJ
cord-263699-gosqpg3k	343	7	membrane	membrane	NN
cord-263699-gosqpg3k	343	8	traffic	traffic	NN
cord-263699-gosqpg3k	343	9	protein	protein	NN
cord-263699-gosqpg3k	343	10	in	in	IN
cord-263699-gosqpg3k	343	11	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	343	12	RNA	RNA	NNP
cord-263699-gosqpg3k	343	13	replication	replication	NN
cord-263699-gosqpg3k	344	1	Poliovirus	Poliovirus	NNP
cord-263699-gosqpg3k	344	2	replication	replication	NN
cord-263699-gosqpg3k	344	3	requires	require	VBZ
cord-263699-gosqpg3k	344	4	the	the	DT
cord-263699-gosqpg3k	344	5	N	n	CD
cord-263699-gosqpg3k	344	6	-	-	HYPH
cord-263699-gosqpg3k	344	7	terminus	terminus	NN
cord-263699-gosqpg3k	344	8	but	but	CC
cord-263699-gosqpg3k	344	9	not	not	RB
cord-263699-gosqpg3k	344	10	the	the	DT
cord-263699-gosqpg3k	344	11	catalytic	catalytic	JJ
cord-263699-gosqpg3k	344	12	Sec7	Sec7	NNP
cord-263699-gosqpg3k	344	13	domain	domain	NN
cord-263699-gosqpg3k	344	14	of	of	IN
cord-263699-gosqpg3k	344	15	ArfGEF	arfgef	JJ
cord-263699-gosqpg3k	344	16	GBF1	GBF1	NNP
cord-263699-gosqpg3k	344	17	Differential	Differential	NNP
cord-263699-gosqpg3k	344	18	Effects	Effects	NNPS
cord-263699-gosqpg3k	344	19	of	of	IN
cord-263699-gosqpg3k	344	20	the	the	DT
cord-263699-gosqpg3k	344	21	putative	putative	JJ
cord-263699-gosqpg3k	344	22	GBF1	GBF1	NNP
cord-263699-gosqpg3k	344	23	inhibitors	inhibitor	NNS
cord-263699-gosqpg3k	344	24	Golgicide	Golgicide	NNP
cord-263699-gosqpg3k	344	25	A	A	NNP
cord-263699-gosqpg3k	344	26	and	and	CC
cord-263699-gosqpg3k	344	27	AG1478	ag1478	NN
cord-263699-gosqpg3k	344	28	on	on	IN
cord-263699-gosqpg3k	344	29	enterovirus	enterovirus	NN
cord-263699-gosqpg3k	344	30	replication	replication	NN
cord-263699-gosqpg3k	344	31	GBF1	GBF1	NNP
cord-263699-gosqpg3k	344	32	,	,	,
cord-263699-gosqpg3k	344	33	a	a	DT
cord-263699-gosqpg3k	344	34	guanine	guanine	NN
cord-263699-gosqpg3k	344	35	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	344	36	exchange	exchange	NN
cord-263699-gosqpg3k	344	37	factor	factor	NN
cord-263699-gosqpg3k	344	38	for	for	IN
cord-263699-gosqpg3k	344	39	Arf	Arf	NNP
cord-263699-gosqpg3k	344	40	,	,	,
cord-263699-gosqpg3k	344	41	is	be	VBZ
cord-263699-gosqpg3k	344	42	crucial	crucial	JJ
cord-263699-gosqpg3k	344	43	for	for	IN
cord-263699-gosqpg3k	344	44	Coxsackievirus	Coxsackievirus	NNP
cord-263699-gosqpg3k	344	45	B3	B3	NNP
cord-263699-gosqpg3k	344	46	RNA	RNA	NNP
cord-263699-gosqpg3k	344	47	replication	replication	NN
cord-263699-gosqpg3k	344	48	Viral	viral	JJ
cord-263699-gosqpg3k	344	49	reorganization	reorganization	NN
cord-263699-gosqpg3k	344	50	of	of	IN
cord-263699-gosqpg3k	344	51	the	the	DT
cord-263699-gosqpg3k	344	52	secretory	secretory	JJ
cord-263699-gosqpg3k	344	53	pathway	pathway	NN
cord-263699-gosqpg3k	344	54	generates	generate	VBZ
cord-263699-gosqpg3k	344	55	distinct	distinct	JJ
cord-263699-gosqpg3k	344	56	organelles	organelle	NNS
cord-263699-gosqpg3k	344	57	for	for	IN
cord-263699-gosqpg3k	344	58	RNA	RNA	NNP
cord-263699-gosqpg3k	344	59	replication	replication	NN
cord-263699-gosqpg3k	344	60	Curcumin	Curcumin	NNP
cord-263699-gosqpg3k	345	1	inhibits	inhibit	VBZ
cord-263699-gosqpg3k	345	2	the	the	DT
cord-263699-gosqpg3k	345	3	replication	replication	NN
cord-263699-gosqpg3k	345	4	of	of	IN
cord-263699-gosqpg3k	345	5	enterovirus	enterovirus	NN
cord-263699-gosqpg3k	345	6	71	71	CD
cord-263699-gosqpg3k	346	1	in	in	FW
cord-263699-gosqpg3k	346	2	vitro	vitro	FW
cord-263699-gosqpg3k	346	3	Class	class	NN
cord-263699-gosqpg3k	347	1	I	i	IN
cord-263699-gosqpg3k	347	2	ADP	ADP	NNP
cord-263699-gosqpg3k	347	3	-	-	HYPH
cord-263699-gosqpg3k	347	4	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	347	5	factors	factor	NNS
cord-263699-gosqpg3k	347	6	are	be	VBP
cord-263699-gosqpg3k	347	7	involved	involve	VBN
cord-263699-gosqpg3k	347	8	in	in	IN
cord-263699-gosqpg3k	347	9	enterovirus	enterovirus	NN
cord-263699-gosqpg3k	347	10	71	71	CD
cord-263699-gosqpg3k	347	11	replication	replication	NN
cord-263699-gosqpg3k	347	12	GBF1-and	GBF1-and	NNP
cord-263699-gosqpg3k	347	13	ACBD3-independent	ACBD3-independent	NNP
cord-263699-gosqpg3k	347	14	recruitment	recruitment	NN
cord-263699-gosqpg3k	347	15	of	of	IN
cord-263699-gosqpg3k	347	16	PI4KIIIβ	PI4KIIIβ	NNP
cord-263699-gosqpg3k	347	17	to	to	TO
cord-263699-gosqpg3k	347	18	replication	replication	VB
cord-263699-gosqpg3k	347	19	sites	site	NNS
cord-263699-gosqpg3k	347	20	by	by	IN
cord-263699-gosqpg3k	347	21	rhinovirus	rhinovirus	NN
cord-263699-gosqpg3k	347	22	3A	3A	NNP
cord-263699-gosqpg3k	347	23	proteins	protein	VBZ
cord-263699-gosqpg3k	347	24	Key	key	JJ
cord-263699-gosqpg3k	347	25	components	component	NNS
cord-263699-gosqpg3k	347	26	of	of	IN
cord-263699-gosqpg3k	347	27	COPI	COPI	NNP
cord-263699-gosqpg3k	347	28	and	and	CC
cord-263699-gosqpg3k	347	29	COPII	COPII	NNP
cord-263699-gosqpg3k	347	30	machineries	machinery	NNS
cord-263699-gosqpg3k	347	31	are	be	VBP
cord-263699-gosqpg3k	347	32	required	require	VBN
cord-263699-gosqpg3k	347	33	for	for	IN
cord-263699-gosqpg3k	347	34	chikungunya	chikungunya	NN
cord-263699-gosqpg3k	347	35	virus	virus	NN
cord-263699-gosqpg3k	347	36	replication	replication	NN
cord-263699-gosqpg3k	347	37	Differential	differential	JJ
cord-263699-gosqpg3k	347	38	inhibition	inhibition	NN
cord-263699-gosqpg3k	347	39	of	of	IN
cord-263699-gosqpg3k	347	40	cellular	cellular	NN
cord-263699-gosqpg3k	347	41	and	and	CC
cord-263699-gosqpg3k	347	42	Sindbis	Sindbis	NNP
cord-263699-gosqpg3k	347	43	virus	virus	NN
cord-263699-gosqpg3k	347	44	translation	translation	NN
cord-263699-gosqpg3k	347	45	by	by	IN
cord-263699-gosqpg3k	347	46	brefeldin	brefeldin	NNP
cord-263699-gosqpg3k	347	47	A.	A.	NNP
cord-263699-gosqpg3k	347	48	Virology	Virology	NNP
cord-263699-gosqpg3k	347	49	Identification	Identification	NNP
cord-263699-gosqpg3k	347	50	of	of	IN
cord-263699-gosqpg3k	347	51	GBF1	GBF1	NNP
cord-263699-gosqpg3k	347	52	as	as	IN
cord-263699-gosqpg3k	347	53	a	a	DT
cord-263699-gosqpg3k	347	54	cellular	cellular	JJ
cord-263699-gosqpg3k	347	55	factor	factor	NN
cord-263699-gosqpg3k	347	56	required	require	VBN
cord-263699-gosqpg3k	347	57	for	for	IN
cord-263699-gosqpg3k	347	58	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	347	59	E	E	NNP
cord-263699-gosqpg3k	347	60	virus	virus	NN
cord-263699-gosqpg3k	347	61	RNA	RNA	NNP
cord-263699-gosqpg3k	347	62	replication	replication	NN
cord-263699-gosqpg3k	347	63	Mouse	Mouse	NNP
cord-263699-gosqpg3k	347	64	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	347	65	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	347	66	RNA	RNA	NNP
cord-263699-gosqpg3k	347	67	replication	replication	NN
cord-263699-gosqpg3k	347	68	depends	depend	VBZ
cord-263699-gosqpg3k	347	69	on	on	IN
cord-263699-gosqpg3k	347	70	GBF1-mediated	GBF1-mediated	NNP
cord-263699-gosqpg3k	347	71	Arf1	Arf1	NNP
cord-263699-gosqpg3k	347	72	activation	activation	NN
cord-263699-gosqpg3k	347	73	Integrity	integrity	NN
cord-263699-gosqpg3k	347	74	of	of	IN
cord-263699-gosqpg3k	347	75	the	the	DT
cord-263699-gosqpg3k	347	76	early	early	JJ
cord-263699-gosqpg3k	347	77	secretory	secretory	JJ
cord-263699-gosqpg3k	347	78	pathway	pathway	NN
cord-263699-gosqpg3k	347	79	promotes	promote	VBZ
cord-263699-gosqpg3k	347	80	,	,	,
cord-263699-gosqpg3k	347	81	but	but	CC
cord-263699-gosqpg3k	347	82	is	be	VBZ
cord-263699-gosqpg3k	347	83	not	not	RB
cord-263699-gosqpg3k	347	84	required	require	VBN
cord-263699-gosqpg3k	347	85	for	for	IN
cord-263699-gosqpg3k	347	86	,	,	,
cord-263699-gosqpg3k	347	87	severe	severe	JJ
cord-263699-gosqpg3k	347	88	acute	acute	JJ
cord-263699-gosqpg3k	347	89	respiratory	respiratory	JJ
cord-263699-gosqpg3k	347	90	syndrome	syndrome	NN
cord-263699-gosqpg3k	347	91	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	347	92	RNA	RNA	NNP
cord-263699-gosqpg3k	347	93	synthesis	synthesis	NN
cord-263699-gosqpg3k	347	94	and	and	CC
cord-263699-gosqpg3k	347	95	virus	virus	NN
cord-263699-gosqpg3k	347	96	-	-	HYPH
cord-263699-gosqpg3k	347	97	induced	induce	VBN
cord-263699-gosqpg3k	347	98	remodeling	remodeling	NN
cord-263699-gosqpg3k	347	99	of	of	IN
cord-263699-gosqpg3k	347	100	endoplasmic	endoplasmic	NN
cord-263699-gosqpg3k	347	101	reticulum	reticulum	NN
cord-263699-gosqpg3k	347	102	membranes	membrane	NNS
cord-263699-gosqpg3k	348	1	A	a	DT
cord-263699-gosqpg3k	348	2	kinome	kinome	NN
cord-263699-gosqpg3k	348	3	-	-	HYPH
cord-263699-gosqpg3k	348	4	wide	wide	JJ
cord-263699-gosqpg3k	348	5	small	small	JJ
cord-263699-gosqpg3k	348	6	interfering	interfere	VBG
cord-263699-gosqpg3k	348	7	RNA	RNA	NNP
cord-263699-gosqpg3k	348	8	screen	screen	NN
cord-263699-gosqpg3k	348	9	identifies	identify	VBZ
cord-263699-gosqpg3k	348	10	proviral	proviral	JJ
cord-263699-gosqpg3k	348	11	and	and	CC
cord-263699-gosqpg3k	348	12	antiviral	antiviral	JJ
cord-263699-gosqpg3k	348	13	host	host	NN
cord-263699-gosqpg3k	348	14	factors	factor	NNS
cord-263699-gosqpg3k	348	15	in	in	IN
cord-263699-gosqpg3k	348	16	severe	severe	JJ
cord-263699-gosqpg3k	348	17	acute	acute	JJ
cord-263699-gosqpg3k	348	18	respiratory	respiratory	JJ
cord-263699-gosqpg3k	348	19	syndrome	syndrome	NN
cord-263699-gosqpg3k	348	20	coronavirus	coronavirus	NN
cord-263699-gosqpg3k	348	21	replication	replication	NN
cord-263699-gosqpg3k	348	22	,	,	,
cord-263699-gosqpg3k	348	23	including	include	VBG
cord-263699-gosqpg3k	348	24	double	double	RB
cord-263699-gosqpg3k	348	25	-	-	HYPH
cord-263699-gosqpg3k	348	26	stranded	strand	VBN
cord-263699-gosqpg3k	348	27	RNA	RNA	NNP
cord-263699-gosqpg3k	348	28	-	-	HYPH
cord-263699-gosqpg3k	348	29	activated	activate	VBN
cord-263699-gosqpg3k	348	30	protein	protein	NN
cord-263699-gosqpg3k	348	31	kinase	kinase	NN
cord-263699-gosqpg3k	348	32	and	and	CC
cord-263699-gosqpg3k	348	33	early	early	JJ
cord-263699-gosqpg3k	348	34	secretory	secretory	JJ
cord-263699-gosqpg3k	348	35	pathway	pathway	NN
cord-263699-gosqpg3k	348	36	proteins	protein	NNS
cord-263699-gosqpg3k	348	37	RNAi	RNAi	NNP
cord-263699-gosqpg3k	348	38	screening	screening	NN
cord-263699-gosqpg3k	349	1	reveals	reveal	VBZ
cord-263699-gosqpg3k	349	2	requirement	requirement	NN
cord-263699-gosqpg3k	349	3	for	for	IN
cord-263699-gosqpg3k	349	4	host	host	NN
cord-263699-gosqpg3k	349	5	cell	cell	NN
cord-263699-gosqpg3k	349	6	secretory	secretory	JJ
cord-263699-gosqpg3k	349	7	pathway	pathway	NN
cord-263699-gosqpg3k	349	8	in	in	IN
cord-263699-gosqpg3k	349	9	infection	infection	NN
cord-263699-gosqpg3k	349	10	by	by	IN
cord-263699-gosqpg3k	349	11	diverse	diverse	JJ
cord-263699-gosqpg3k	349	12	families	family	NNS
cord-263699-gosqpg3k	349	13	of	of	IN
cord-263699-gosqpg3k	349	14	negative	negative	JJ
cord-263699-gosqpg3k	349	15	-	-	HYPH
cord-263699-gosqpg3k	349	16	strand	strand	NN
cord-263699-gosqpg3k	349	17	RNA	RNA	NNP
cord-263699-gosqpg3k	349	18	viruses	virus	NNS
cord-263699-gosqpg3k	349	19	Dissecting	dissect	VBG
cord-263699-gosqpg3k	349	20	the	the	DT
cord-263699-gosqpg3k	349	21	role	role	NN
cord-263699-gosqpg3k	349	22	of	of	IN
cord-263699-gosqpg3k	349	23	COPI	COPI	NNP
cord-263699-gosqpg3k	349	24	complexes	complex	NNS
cord-263699-gosqpg3k	349	25	in	in	IN
cord-263699-gosqpg3k	349	26	influenza	influenza	NN
cord-263699-gosqpg3k	349	27	virus	virus	NN
cord-263699-gosqpg3k	349	28	infection	infection	NN
cord-263699-gosqpg3k	349	29	Influenza	Influenza	NNP
cord-263699-gosqpg3k	349	30	virus	virus	NN
cord-263699-gosqpg3k	349	31	-	-	HYPH
cord-263699-gosqpg3k	349	32	host	host	NN
cord-263699-gosqpg3k	349	33	interactome	interactome	NN
cord-263699-gosqpg3k	349	34	screen	screen	NN
cord-263699-gosqpg3k	349	35	as	as	IN
cord-263699-gosqpg3k	349	36	a	a	DT
cord-263699-gosqpg3k	349	37	platform	platform	NN
cord-263699-gosqpg3k	349	38	for	for	IN
cord-263699-gosqpg3k	349	39	antiviral	antiviral	JJ
cord-263699-gosqpg3k	349	40	drug	drug	NN
cord-263699-gosqpg3k	349	41	development	development	NN
cord-263699-gosqpg3k	349	42	Influenza	Influenza	NNP
cord-263699-gosqpg3k	349	43	infection	infection	NN
cord-263699-gosqpg3k	349	44	modulates	modulate	VBZ
cord-263699-gosqpg3k	349	45	vesicular	vesicular	JJ
cord-263699-gosqpg3k	349	46	trafficking	trafficking	NN
cord-263699-gosqpg3k	349	47	and	and	CC
cord-263699-gosqpg3k	349	48	induces	induce	VBZ
cord-263699-gosqpg3k	349	49	Golgi	Golgi	NNP
cord-263699-gosqpg3k	349	50	complex	complex	JJ
cord-263699-gosqpg3k	349	51	disruption	disruption	NN
cord-263699-gosqpg3k	349	52	The	the	DT
cord-263699-gosqpg3k	349	53	guanine	guanine	NN
cord-263699-gosqpg3k	349	54	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	349	55	exchange	exchange	NN
cord-263699-gosqpg3k	349	56	factor	factor	NN
cord-263699-gosqpg3k	349	57	GBF1	GBF1	NNP
cord-263699-gosqpg3k	349	58	participates	participate	VBZ
cord-263699-gosqpg3k	349	59	in	in	IN
cord-263699-gosqpg3k	349	60	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	349	61	replication	replication	NN
cord-263699-gosqpg3k	349	62	Coupling	Coupling	NNP
cord-263699-gosqpg3k	349	63	of	of	IN
cord-263699-gosqpg3k	349	64	replication	replication	NN
cord-263699-gosqpg3k	349	65	and	and	CC
cord-263699-gosqpg3k	349	66	assembly	assembly	NN
cord-263699-gosqpg3k	349	67	in	in	IN
cord-263699-gosqpg3k	349	68	flaviviruses	flavivirus	NNS
cord-263699-gosqpg3k	350	1	Dengue	dengue	NN
cord-263699-gosqpg3k	350	2	virus	virus	NN
cord-263699-gosqpg3k	350	3	capsid	capsid	NN
cord-263699-gosqpg3k	350	4	protein	protein	NN
cord-263699-gosqpg3k	350	5	usurps	usurp	VBZ
cord-263699-gosqpg3k	350	6	lipid	lipid	NN
cord-263699-gosqpg3k	350	7	droplets	droplet	NNS
cord-263699-gosqpg3k	350	8	for	for	IN
cord-263699-gosqpg3k	350	9	viral	viral	JJ
cord-263699-gosqpg3k	350	10	particle	particle	NN
cord-263699-gosqpg3k	350	11	formation	formation	NN
cord-263699-gosqpg3k	350	12	Quantitative	quantitative	JJ
cord-263699-gosqpg3k	350	13	proteomic	proteomic	JJ
cord-263699-gosqpg3k	350	14	analysis	analysis	NN
cord-263699-gosqpg3k	350	15	of	of	IN
cord-263699-gosqpg3k	350	16	host	host	NN
cord-263699-gosqpg3k	350	17	-	-	HYPH
cord-263699-gosqpg3k	350	18	virus	virus	NN
cord-263699-gosqpg3k	350	19	interactions	interaction	NNS
cord-263699-gosqpg3k	350	20	reveals	reveal	VBZ
cord-263699-gosqpg3k	350	21	a	a	DT
cord-263699-gosqpg3k	350	22	role	role	NN
cord-263699-gosqpg3k	350	23	for	for	IN
cord-263699-gosqpg3k	350	24	Golgi	Golgi	NNP
cord-263699-gosqpg3k	350	25	brefeldin	brefeldin	NNP
cord-263699-gosqpg3k	351	1	A	a	DT
cord-263699-gosqpg3k	351	2	resistance	resistance	NN
cord-263699-gosqpg3k	351	3	Factor	factor	NN
cord-263699-gosqpg3k	351	4	1	1	CD
cord-263699-gosqpg3k	351	5	(	(	-LRB-
cord-263699-gosqpg3k	351	6	GBF1	GBF1	NNP
cord-263699-gosqpg3k	351	7	)	)	-RRB-
cord-263699-gosqpg3k	351	8	in	in	IN
cord-263699-gosqpg3k	351	9	dengue	dengue	NN
cord-263699-gosqpg3k	351	10	Infection	Infection	NNP
cord-263699-gosqpg3k	351	11	Class	Class	NNP
cord-263699-gosqpg3k	351	12	II	II	NNP
cord-263699-gosqpg3k	351	13	ADP	adp	NN
cord-263699-gosqpg3k	351	14	-	-	HYPH
cord-263699-gosqpg3k	351	15	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	351	16	factors	factor	NNS
cord-263699-gosqpg3k	351	17	are	be	VBP
cord-263699-gosqpg3k	351	18	required	require	VBN
cord-263699-gosqpg3k	351	19	for	for	IN
cord-263699-gosqpg3k	351	20	efficient	efficient	JJ
cord-263699-gosqpg3k	351	21	secretion	secretion	NN
cord-263699-gosqpg3k	351	22	of	of	IN
cord-263699-gosqpg3k	351	23	dengue	dengue	NN
cord-263699-gosqpg3k	351	24	viruses	virus	NNS
cord-263699-gosqpg3k	352	1	Brefeldin	Brefeldin	NNP
cord-263699-gosqpg3k	352	2	A	A	NNP
cord-263699-gosqpg3k	352	3	and	and	CC
cord-263699-gosqpg3k	352	4	cytochalasin	cytochalasin	NNP
cord-263699-gosqpg3k	352	5	B	B	NNP
cord-263699-gosqpg3k	352	6	reduce	reduce	VB
cord-263699-gosqpg3k	352	7	dengue	dengue	NN
cord-263699-gosqpg3k	352	8	virus	virus	NN
cord-263699-gosqpg3k	352	9	replication	replication	NN
cord-263699-gosqpg3k	352	10	in	in	IN
cord-263699-gosqpg3k	352	11	cell	cell	NN
cord-263699-gosqpg3k	352	12	cultures	culture	NNS
cord-263699-gosqpg3k	352	13	but	but	CC
cord-263699-gosqpg3k	352	14	do	do	VBP
cord-263699-gosqpg3k	352	15	not	not	RB
cord-263699-gosqpg3k	352	16	protect	protect	VB
cord-263699-gosqpg3k	352	17	mice	mouse	NNS
cord-263699-gosqpg3k	352	18	against	against	IN
cord-263699-gosqpg3k	352	19	viral	viral	JJ
cord-263699-gosqpg3k	352	20	challenge	challenge	NN
cord-263699-gosqpg3k	353	1	Viperin	Viperin	NNP
cord-263699-gosqpg3k	353	2	is	be	VBZ
cord-263699-gosqpg3k	353	3	induced	induce	VBN
cord-263699-gosqpg3k	353	4	following	follow	VBG
cord-263699-gosqpg3k	353	5	dengue	dengue	NN
cord-263699-gosqpg3k	353	6	virus	virus	NN
cord-263699-gosqpg3k	353	7	type-2	type-2	NNP
cord-263699-gosqpg3k	353	8	(	(	-LRB-
cord-263699-gosqpg3k	353	9	DENV-2	DENV-2	NNP
cord-263699-gosqpg3k	353	10	)	)	-RRB-
cord-263699-gosqpg3k	353	11	infection	infection	NN
cord-263699-gosqpg3k	353	12	and	and	CC
cord-263699-gosqpg3k	353	13	has	have	VBZ
cord-263699-gosqpg3k	353	14	anti	anti	JJ
cord-263699-gosqpg3k	353	15	-	-	JJ
cord-263699-gosqpg3k	353	16	viral	viral	JJ
cord-263699-gosqpg3k	353	17	actions	action	NNS
cord-263699-gosqpg3k	353	18	requiring	require	VBG
cord-263699-gosqpg3k	353	19	the	the	DT
cord-263699-gosqpg3k	353	20	C	c	NN
cord-263699-gosqpg3k	353	21	-	-	HYPH
cord-263699-gosqpg3k	353	22	terminal	terminal	JJ
cord-263699-gosqpg3k	353	23	end	end	NN
cord-263699-gosqpg3k	353	24	of	of	IN
cord-263699-gosqpg3k	353	25	viperin	viperin	NNP
cord-263699-gosqpg3k	354	1	The	the	DT
cord-263699-gosqpg3k	354	2	Interferon	interferon	NN
cord-263699-gosqpg3k	354	3	-	-	HYPH
cord-263699-gosqpg3k	354	4	inducible	inducible	JJ
cord-263699-gosqpg3k	354	5	gene	gene	NN
cord-263699-gosqpg3k	354	6	viperin	viperin	NNP
cord-263699-gosqpg3k	354	7	restricts	restrict	VBZ
cord-263699-gosqpg3k	354	8	West	West	NNP
cord-263699-gosqpg3k	354	9	Nile	Nile	NNP
cord-263699-gosqpg3k	354	10	virus	virus	NN
cord-263699-gosqpg3k	354	11	pathogenesis	pathogenesis	NN
cord-263699-gosqpg3k	354	12	Role	role	NN
cord-263699-gosqpg3k	354	13	of	of	IN
cord-263699-gosqpg3k	354	14	Rab	Rab	NNP
cord-263699-gosqpg3k	354	15	GTPases	GTPases	NNP
cord-263699-gosqpg3k	354	16	in	in	IN
cord-263699-gosqpg3k	354	17	membrane	membrane	NN
cord-263699-gosqpg3k	354	18	traffic	traffic	NN
cord-263699-gosqpg3k	354	19	and	and	CC
cord-263699-gosqpg3k	354	20	cell	cell	NN
cord-263699-gosqpg3k	354	21	physiology	physiology	NN
cord-263699-gosqpg3k	354	22	Hepatitis	Hepatitis	NNP
cord-263699-gosqpg3k	354	23	C	C	NNP
cord-263699-gosqpg3k	354	24	virus	virus	NN
cord-263699-gosqpg3k	354	25	:	:	:
cord-263699-gosqpg3k	354	26	Virology	virology	NN
cord-263699-gosqpg3k	354	27	and	and	CC
cord-263699-gosqpg3k	354	28	life	life	NN
cord-263699-gosqpg3k	354	29	cycle	cycle	NN
cord-263699-gosqpg3k	354	30	Hepatitis	Hepatitis	NNP
cord-263699-gosqpg3k	354	31	C	C	NNP
cord-263699-gosqpg3k	354	32	Virus	Virus	NNP
cord-263699-gosqpg3k	354	33	RNA	RNA	NNP
cord-263699-gosqpg3k	354	34	replication	replication	NN
cord-263699-gosqpg3k	354	35	and	and	CC
cord-263699-gosqpg3k	354	36	assembly	assembly	NN
cord-263699-gosqpg3k	354	37	:	:	:
cord-263699-gosqpg3k	355	1	Living	live	VBG
cord-263699-gosqpg3k	355	2	on	on	IN
cord-263699-gosqpg3k	355	3	the	the	DT
cord-263699-gosqpg3k	355	4	fat	fat	NN
cord-263699-gosqpg3k	355	5	of	of	IN
cord-263699-gosqpg3k	355	6	the	the	DT
cord-263699-gosqpg3k	355	7	land	land	NN
cord-263699-gosqpg3k	355	8	Expression	Expression	NNP
cord-263699-gosqpg3k	355	9	of	of	IN
cord-263699-gosqpg3k	355	10	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	355	11	C	C	NNP
cord-263699-gosqpg3k	355	12	virus	virus	NN
cord-263699-gosqpg3k	355	13	proteins	protein	NNS
cord-263699-gosqpg3k	355	14	induces	induce	VBZ
cord-263699-gosqpg3k	355	15	distinct	distinct	JJ
cord-263699-gosqpg3k	355	16	membrane	membrane	NN
cord-263699-gosqpg3k	355	17	alterations	alteration	NNS
cord-263699-gosqpg3k	355	18	including	include	VBG
cord-263699-gosqpg3k	355	19	a	a	DT
cord-263699-gosqpg3k	355	20	candidate	candidate	NN
cord-263699-gosqpg3k	355	21	viral	viral	JJ
cord-263699-gosqpg3k	355	22	replication	replication	NN
cord-263699-gosqpg3k	355	23	complex	complex	JJ
cord-263699-gosqpg3k	355	24	Three	three	CD
cord-263699-gosqpg3k	355	25	-	-	HYPH
cord-263699-gosqpg3k	355	26	dimensional	dimensional	JJ
cord-263699-gosqpg3k	355	27	architecture	architecture	NN
cord-263699-gosqpg3k	355	28	and	and	CC
cord-263699-gosqpg3k	355	29	biogenesis	biogenesis	NN
cord-263699-gosqpg3k	355	30	of	of	IN
cord-263699-gosqpg3k	355	31	membrane	membrane	NN
cord-263699-gosqpg3k	355	32	structures	structure	NNS
cord-263699-gosqpg3k	355	33	associated	associate	VBN
cord-263699-gosqpg3k	355	34	with	with	IN
cord-263699-gosqpg3k	355	35	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	355	36	C	C	NNP
cord-263699-gosqpg3k	355	37	virus	virus	NN
cord-263699-gosqpg3k	355	38	replication	replication	NN
cord-263699-gosqpg3k	355	39	Hepatitis	Hepatitis	NNP
cord-263699-gosqpg3k	355	40	C	C	NNP
cord-263699-gosqpg3k	355	41	virus	virus	NN
cord-263699-gosqpg3k	355	42	:	:	:
cord-263699-gosqpg3k	355	43	Life	life	NN
cord-263699-gosqpg3k	355	44	cycle	cycle	NN
cord-263699-gosqpg3k	355	45	in	in	IN
cord-263699-gosqpg3k	355	46	cells	cell	NNS
cord-263699-gosqpg3k	355	47	,	,	,
cord-263699-gosqpg3k	355	48	infection	infection	NN
cord-263699-gosqpg3k	355	49	and	and	CC
cord-263699-gosqpg3k	355	50	host	host	NN
cord-263699-gosqpg3k	355	51	response	response	NN
cord-263699-gosqpg3k	355	52	,	,	,
cord-263699-gosqpg3k	355	53	and	and	CC
cord-263699-gosqpg3k	355	54	analysis	analysis	NN
cord-263699-gosqpg3k	355	55	of	of	IN
cord-263699-gosqpg3k	355	56	molecular	molecular	JJ
cord-263699-gosqpg3k	355	57	markers	marker	NNS
cord-263699-gosqpg3k	355	58	influencing	influence	VBG
cord-263699-gosqpg3k	355	59	the	the	DT
cord-263699-gosqpg3k	355	60	outcome	outcome	NN
cord-263699-gosqpg3k	355	61	of	of	IN
cord-263699-gosqpg3k	355	62	infection	infection	NN
cord-263699-gosqpg3k	355	63	and	and	CC
cord-263699-gosqpg3k	355	64	response	response	NN
cord-263699-gosqpg3k	355	65	to	to	IN
cord-263699-gosqpg3k	355	66	therapy	therapy	NN
cord-263699-gosqpg3k	355	67	Role	role	NN
cord-263699-gosqpg3k	355	68	for	for	IN
cord-263699-gosqpg3k	355	69	ADP	ADP	NNP
cord-263699-gosqpg3k	355	70	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	355	71	factor	factor	NN
cord-263699-gosqpg3k	355	72	1	1	CD
cord-263699-gosqpg3k	355	73	in	in	IN
cord-263699-gosqpg3k	355	74	the	the	DT
cord-263699-gosqpg3k	355	75	regulation	regulation	NN
cord-263699-gosqpg3k	355	76	of	of	IN
cord-263699-gosqpg3k	355	77	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	355	78	C	C	NNP
cord-263699-gosqpg3k	355	79	virus	virus	NN
cord-263699-gosqpg3k	355	80	replication	replication	NN
cord-263699-gosqpg3k	355	81	Identification	Identification	NNP
cord-263699-gosqpg3k	355	82	of	of	IN
cord-263699-gosqpg3k	355	83	class	class	NN
cord-263699-gosqpg3k	355	84	II	II	NNP
cord-263699-gosqpg3k	355	85	ADP	adp	NN
cord-263699-gosqpg3k	355	86	-	-	HYPH
cord-263699-gosqpg3k	355	87	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	355	88	factors	factor	NNS
cord-263699-gosqpg3k	355	89	as	as	IN
cord-263699-gosqpg3k	355	90	cellular	cellular	JJ
cord-263699-gosqpg3k	355	91	factors	factor	NNS
cord-263699-gosqpg3k	355	92	required	require	VBN
cord-263699-gosqpg3k	355	93	for	for	IN
cord-263699-gosqpg3k	355	94	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	355	95	C	C	NNP
cord-263699-gosqpg3k	355	96	virus	virus	NN
cord-263699-gosqpg3k	355	97	replication	replication	NN
cord-263699-gosqpg3k	355	98	Arf1	Arf1	NNP
cord-263699-gosqpg3k	355	99	activation	activation	NN
cord-263699-gosqpg3k	355	100	dissociates	dissociate	VBZ
cord-263699-gosqpg3k	355	101	ADRP	ADRP	NNP
cord-263699-gosqpg3k	355	102	from	from	IN
cord-263699-gosqpg3k	355	103	lipid	lipid	NN
cord-263699-gosqpg3k	355	104	droplets	droplet	NNS
cord-263699-gosqpg3k	355	105	to	to	TO
cord-263699-gosqpg3k	355	106	promote	promote	VB
cord-263699-gosqpg3k	355	107	HCV	HCV	NNP
cord-263699-gosqpg3k	355	108	assembly	assembly	NN
cord-263699-gosqpg3k	355	109	Cellular	cellular	JJ
cord-263699-gosqpg3k	355	110	lipid	lipid	NN
cord-263699-gosqpg3k	355	111	droplets	droplet	NNS
cord-263699-gosqpg3k	355	112	and	and	CC
cord-263699-gosqpg3k	355	113	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	355	114	C	C	NNP
cord-263699-gosqpg3k	355	115	virus	virus	NN
cord-263699-gosqpg3k	355	116	life	life	NN
cord-263699-gosqpg3k	355	117	cycle	cycle	NN
cord-263699-gosqpg3k	355	118	Cellular	cellular	JJ
cord-263699-gosqpg3k	355	119	determinants	determinant	NNS
cord-263699-gosqpg3k	355	120	of	of	IN
cord-263699-gosqpg3k	355	121	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	355	122	C	C	NNP
cord-263699-gosqpg3k	355	123	virus	virus	NN
cord-263699-gosqpg3k	355	124	assembly	assembly	NN
cord-263699-gosqpg3k	355	125	,	,	,
cord-263699-gosqpg3k	355	126	maturation	maturation	NN
cord-263699-gosqpg3k	355	127	,	,	,
cord-263699-gosqpg3k	355	128	degradation	degradation	NN
cord-263699-gosqpg3k	355	129	,	,	,
cord-263699-gosqpg3k	355	130	and	and	CC
cord-263699-gosqpg3k	355	131	secretion	secretion	NN
cord-263699-gosqpg3k	355	132	Hepatitis	Hepatitis	NNP
cord-263699-gosqpg3k	355	133	C	C	NNP
cord-263699-gosqpg3k	355	134	virus	virus	NN
cord-263699-gosqpg3k	355	135	replication	replication	NN
cord-263699-gosqpg3k	355	136	and	and	CC
cord-263699-gosqpg3k	355	137	Golgi	Golgi	NNP
cord-263699-gosqpg3k	355	138	function	function	NN
cord-263699-gosqpg3k	355	139	in	in	IN
cord-263699-gosqpg3k	355	140	brefeldin	brefeldin	NNP
cord-263699-gosqpg3k	355	141	A	A	NNP
cord-263699-gosqpg3k	355	142	-	-	HYPH
cord-263699-gosqpg3k	355	143	resistant	resistant	JJ
cord-263699-gosqpg3k	355	144	hepatoma	hepatoma	NN
cord-263699-gosqpg3k	355	145	-	-	HYPH
cord-263699-gosqpg3k	355	146	derived	derive	VBN
cord-263699-gosqpg3k	355	147	cells	cell	NNS
cord-263699-gosqpg3k	355	148	Hepatitis	Hepatitis	NNP
cord-263699-gosqpg3k	355	149	C	C	NNP
cord-263699-gosqpg3k	355	150	virus	virus	NN
cord-263699-gosqpg3k	356	1	NS5A	NS5A	NNP
cord-263699-gosqpg3k	356	2	hijacks	hijack	VBZ
cord-263699-gosqpg3k	356	3	ArfGAP1	arfgap1	NN
cord-263699-gosqpg3k	356	4	to	to	TO
cord-263699-gosqpg3k	356	5	maintain	maintain	VB
cord-263699-gosqpg3k	356	6	a	a	DT
cord-263699-gosqpg3k	356	7	phosphatidylinositol	phosphatidylinositol	JJ
cord-263699-gosqpg3k	356	8	4-phosphate	4-phosphate	CD
cord-263699-gosqpg3k	356	9	-	-	HYPH
cord-263699-gosqpg3k	356	10	enriched	enrich	VBN
cord-263699-gosqpg3k	356	11	microenvironment	microenvironment	NN
cord-263699-gosqpg3k	356	12	Phosphatidylinositol	Phosphatidylinositol	NNP
cord-263699-gosqpg3k	356	13	4-kinases	4-kinases	CD
cord-263699-gosqpg3k	356	14	:	:	:
cord-263699-gosqpg3k	357	1	Old	old	JJ
cord-263699-gosqpg3k	357	2	enzymes	enzyme	NNS
cord-263699-gosqpg3k	357	3	with	with	IN
cord-263699-gosqpg3k	357	4	emerging	emerge	VBG
cord-263699-gosqpg3k	357	5	functions	function	NNS
cord-263699-gosqpg3k	357	6	Functional	functional	JJ
cord-263699-gosqpg3k	357	7	and	and	CC
cord-263699-gosqpg3k	357	8	physical	physical	JJ
cord-263699-gosqpg3k	357	9	interaction	interaction	NN
cord-263699-gosqpg3k	357	10	between	between	IN
cord-263699-gosqpg3k	357	11	the	the	DT
cord-263699-gosqpg3k	357	12	Arf	Arf	NNP
cord-263699-gosqpg3k	357	13	Activator	Activator	NNP
cord-263699-gosqpg3k	357	14	GBF1	GBF1	NNP
cord-263699-gosqpg3k	357	15	and	and	CC
cord-263699-gosqpg3k	357	16	hepatitis	hepatitis	NN
cord-263699-gosqpg3k	357	17	C	C	NNP
cord-263699-gosqpg3k	357	18	virus	virus	NN
cord-263699-gosqpg3k	357	19	NS3	ns3	RB
cord-263699-gosqpg3k	357	20	Protein	Protein	NNP
cord-263699-gosqpg3k	357	21	Inhibition	Inhibition	NNP
cord-263699-gosqpg3k	357	22	of	of	IN
cord-263699-gosqpg3k	357	23	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	357	24	RNA	RNA	NNP
cord-263699-gosqpg3k	357	25	synthesis	synthesis	NN
cord-263699-gosqpg3k	357	26	by	by	IN
cord-263699-gosqpg3k	357	27	brefeldin	brefeldin	NNP
cord-263699-gosqpg3k	358	1	A	a	DT
cord-263699-gosqpg3k	358	2	Brefeldin	Brefeldin	NNP
cord-263699-gosqpg3k	358	3	A	A	NNP
cord-263699-gosqpg3k	358	4	inhibits	inhibit	VBZ
cord-263699-gosqpg3k	359	1	cell	cell	NN
cord-263699-gosqpg3k	359	2	-	-	HYPH
cord-263699-gosqpg3k	359	3	free	free	JJ
cord-263699-gosqpg3k	359	4	,	,	,
cord-263699-gosqpg3k	359	5	de	de	FW
cord-263699-gosqpg3k	359	6	novo	novo	NNP
cord-263699-gosqpg3k	359	7	synthesis	synthesis	NN
cord-263699-gosqpg3k	359	8	of	of	IN
cord-263699-gosqpg3k	359	9	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	359	10	COPI	COPI	NNP
cord-263699-gosqpg3k	359	11	is	be	VBZ
cord-263699-gosqpg3k	359	12	required	require	VBN
cord-263699-gosqpg3k	359	13	for	for	IN
cord-263699-gosqpg3k	359	14	enterovirus	enterovirus	NN
cord-263699-gosqpg3k	359	15	71	71	CD
cord-263699-gosqpg3k	359	16	replication	replication	NN
cord-263699-gosqpg3k	359	17	Differential	Differential	NNP
cord-263699-gosqpg3k	359	18	Requirements	requirement	NNS
cord-263699-gosqpg3k	359	19	for	for	IN
cord-263699-gosqpg3k	359	20	COPI	COPI	NNP
cord-263699-gosqpg3k	359	21	coats	coat	NNS
cord-263699-gosqpg3k	359	22	in	in	IN
cord-263699-gosqpg3k	359	23	formation	formation	NN
cord-263699-gosqpg3k	359	24	of	of	IN
cord-263699-gosqpg3k	359	25	replication	replication	NN
cord-263699-gosqpg3k	359	26	complexes	complex	NNS
cord-263699-gosqpg3k	359	27	among	among	IN
cord-263699-gosqpg3k	359	28	three	three	CD
cord-263699-gosqpg3k	359	29	genera	genus	NNS
cord-263699-gosqpg3k	359	30	of	of	IN
cord-263699-gosqpg3k	359	31	Picornaviridae	Picornaviridae	NNP
cord-263699-gosqpg3k	359	32	Subcellular	Subcellular	NNP
cord-263699-gosqpg3k	359	33	distribution	distribution	NN
cord-263699-gosqpg3k	359	34	of	of	IN
cord-263699-gosqpg3k	359	35	the	the	DT
cord-263699-gosqpg3k	359	36	foot	foot	NN
cord-263699-gosqpg3k	359	37	-	-	HYPH
cord-263699-gosqpg3k	359	38	and	and	CC
cord-263699-gosqpg3k	359	39	-	-	HYPH
cord-263699-gosqpg3k	359	40	mouth	mouth	NN
cord-263699-gosqpg3k	359	41	disease	disease	NN
cord-263699-gosqpg3k	359	42	virus	virus	NN
cord-263699-gosqpg3k	359	43	3A	3A	NNP
cord-263699-gosqpg3k	359	44	protein	protein	NN
cord-263699-gosqpg3k	359	45	in	in	IN
cord-263699-gosqpg3k	359	46	cells	cell	NNS
cord-263699-gosqpg3k	359	47	infected	infect	VBN
cord-263699-gosqpg3k	359	48	with	with	IN
cord-263699-gosqpg3k	359	49	viruses	virus	NNS
cord-263699-gosqpg3k	359	50	encoding	encode	VBG
cord-263699-gosqpg3k	359	51	wild	wild	JJ
cord-263699-gosqpg3k	359	52	-	-	HYPH
cord-263699-gosqpg3k	359	53	type	type	NN
cord-263699-gosqpg3k	359	54	and	and	CC
cord-263699-gosqpg3k	359	55	bovine	bovine	NN
cord-263699-gosqpg3k	359	56	-	-	HYPH
cord-263699-gosqpg3k	359	57	attenuated	attenuated	JJ
cord-263699-gosqpg3k	359	58	forms	form	NNS
cord-263699-gosqpg3k	359	59	of	of	IN
cord-263699-gosqpg3k	359	60	3A	3A	NNP
cord-263699-gosqpg3k	359	61	Hijacking	hijacking	NN
cord-263699-gosqpg3k	359	62	components	component	NNS
cord-263699-gosqpg3k	359	63	of	of	IN
cord-263699-gosqpg3k	359	64	the	the	DT
cord-263699-gosqpg3k	359	65	cellular	cellular	JJ
cord-263699-gosqpg3k	359	66	secretory	secretory	JJ
cord-263699-gosqpg3k	359	67	pathway	pathway	NN
cord-263699-gosqpg3k	359	68	for	for	IN
cord-263699-gosqpg3k	359	69	replication	replication	NN
cord-263699-gosqpg3k	359	70	of	of	IN
cord-263699-gosqpg3k	359	71	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	359	72	RNA	RNA	NNP
cord-263699-gosqpg3k	359	73	A	a	DT
cord-263699-gosqpg3k	359	74	viral	viral	JJ
cord-263699-gosqpg3k	359	75	protein	protein	NN
cord-263699-gosqpg3k	359	76	that	that	WDT
cord-263699-gosqpg3k	359	77	blocks	block	VBZ
cord-263699-gosqpg3k	359	78	Arf1-mediated	arf1-mediate	VBN
cord-263699-gosqpg3k	359	79	COP	cop	NN
cord-263699-gosqpg3k	360	1	-I	-i	DT
cord-263699-gosqpg3k	360	2	assembly	assembly	NN
cord-263699-gosqpg3k	360	3	by	by	IN
cord-263699-gosqpg3k	360	4	inhibiting	inhibit	VBG
cord-263699-gosqpg3k	360	5	the	the	DT
cord-263699-gosqpg3k	360	6	guanine	guanine	NN
cord-263699-gosqpg3k	360	7	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	360	8	exchange	exchange	NN
cord-263699-gosqpg3k	360	9	factor	factor	NN
cord-263699-gosqpg3k	360	10	GBF1	GBF1	NNP
cord-263699-gosqpg3k	360	11	A	a	DT
cord-263699-gosqpg3k	360	12	Proline	proline	NN
cord-263699-gosqpg3k	360	13	-	-	HYPH
cord-263699-gosqpg3k	360	14	rich	rich	JJ
cord-263699-gosqpg3k	360	15	region	region	NN
cord-263699-gosqpg3k	360	16	in	in	IN
cord-263699-gosqpg3k	360	17	the	the	DT
cord-263699-gosqpg3k	360	18	coxackievirus	coxackievirus	NNP
cord-263699-gosqpg3k	361	1	3A	3A	NNP
cord-263699-gosqpg3k	361	2	protein	protein	NNP
cord-263699-gosqpg3k	361	3	is	be	VBZ
cord-263699-gosqpg3k	361	4	required	require	VBN
cord-263699-gosqpg3k	361	5	for	for	IN
cord-263699-gosqpg3k	361	6	the	the	DT
cord-263699-gosqpg3k	361	7	protein	protein	NN
cord-263699-gosqpg3k	361	8	to	to	TO
cord-263699-gosqpg3k	361	9	inhibit	inhibit	VB
cord-263699-gosqpg3k	361	10	endoplasmic	endoplasmic	NN
cord-263699-gosqpg3k	361	11	reticulum	reticulum	NN
cord-263699-gosqpg3k	361	12	to	to	IN
cord-263699-gosqpg3k	361	13	Golgi	Golgi	NNP
cord-263699-gosqpg3k	361	14	transport	transport	NN
cord-263699-gosqpg3k	361	15	Effects	effect	NNS
cord-263699-gosqpg3k	361	16	of	of	IN
cord-263699-gosqpg3k	361	17	picornavirus	picornavirus	NNP
cord-263699-gosqpg3k	361	18	3A	3A	NNP
cord-263699-gosqpg3k	361	19	proteins	protein	NNS
cord-263699-gosqpg3k	361	20	on	on	IN
cord-263699-gosqpg3k	361	21	protein	protein	NN
cord-263699-gosqpg3k	361	22	transport	transport	NN
cord-263699-gosqpg3k	361	23	and	and	CC
cord-263699-gosqpg3k	361	24	GBF1-dependent	GBF1-dependent	NNP
cord-263699-gosqpg3k	361	25	COP-	COP-	NNP
cord-263699-gosqpg3k	362	1	I	-PRON-	PRP
cord-263699-gosqpg3k	362	2	recruitment	recruitment	VBP
cord-263699-gosqpg3k	362	3	Molecular	molecular	JJ
cord-263699-gosqpg3k	362	4	determinants	determinant	NNS
cord-263699-gosqpg3k	362	5	of	of	IN
cord-263699-gosqpg3k	362	6	the	the	DT
cord-263699-gosqpg3k	362	7	interaction	interaction	NN
cord-263699-gosqpg3k	362	8	between	between	IN
cord-263699-gosqpg3k	362	9	coxsackievirus	coxsackievirus	NNP
cord-263699-gosqpg3k	362	10	protein	protein	NNP
cord-263699-gosqpg3k	362	11	3A	3A	NNP
cord-263699-gosqpg3k	362	12	and	and	CC
cord-263699-gosqpg3k	363	1	guanine	guanine	NNP
cord-263699-gosqpg3k	363	2	nucleotide	nucleotide	JJ
cord-263699-gosqpg3k	363	3	exchange	exchange	NN
cord-263699-gosqpg3k	363	4	factor	factor	NN
cord-263699-gosqpg3k	363	5	GBF1	GBF1	NNP
cord-263699-gosqpg3k	363	6	Poliovirus	Poliovirus	NNP
cord-263699-gosqpg3k	363	7	proteins	protein	NNS
cord-263699-gosqpg3k	363	8	induce	induce	VBP
cord-263699-gosqpg3k	363	9	membrane	membrane	NN
cord-263699-gosqpg3k	363	10	association	association	NN
cord-263699-gosqpg3k	363	11	of	of	IN
cord-263699-gosqpg3k	363	12	GTPase	GTPase	NNP
cord-263699-gosqpg3k	363	13	ADP	ADP	NNP
cord-263699-gosqpg3k	363	14	-	-	HYPH
cord-263699-gosqpg3k	363	15	ribosylation	ribosylation	NN
cord-263699-gosqpg3k	363	16	factor	factor	NN
cord-263699-gosqpg3k	363	17	Inhibition	inhibition	NN
cord-263699-gosqpg3k	363	18	of	of	IN
cord-263699-gosqpg3k	363	19	cellular	cellular	JJ
cord-263699-gosqpg3k	363	20	protein	protein	NN
cord-263699-gosqpg3k	363	21	secretion	secretion	NN
cord-263699-gosqpg3k	363	22	by	by	IN
cord-263699-gosqpg3k	363	23	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	363	24	proteins	protein	NNS
cord-263699-gosqpg3k	363	25	2B	2b	CD
cord-263699-gosqpg3k	363	26	and	and	CC
cord-263699-gosqpg3k	363	27	3A	3A	NNP
cord-263699-gosqpg3k	363	28	Rewiring	Rewiring	NNP
cord-263699-gosqpg3k	363	29	of	of	IN
cord-263699-gosqpg3k	363	30	cellular	cellular	JJ
cord-263699-gosqpg3k	363	31	membrane	membrane	NN
cord-263699-gosqpg3k	363	32	homeostasis	homeostasis	NN
cord-263699-gosqpg3k	363	33	by	by	IN
cord-263699-gosqpg3k	363	34	picornaviruses	picornaviruses	NNP
cord-263699-gosqpg3k	363	35	Phospholipid	Phospholipid	NNP
cord-263699-gosqpg3k	363	36	synthesis	synthesis	NN
cord-263699-gosqpg3k	363	37	fueled	fuel	VBN
cord-263699-gosqpg3k	363	38	by	by	IN
cord-263699-gosqpg3k	363	39	lipid	lipid	NN
cord-263699-gosqpg3k	363	40	droplets	droplet	NNS
cord-263699-gosqpg3k	363	41	drives	drive	VBZ
cord-263699-gosqpg3k	363	42	the	the	DT
cord-263699-gosqpg3k	363	43	structural	structural	JJ
cord-263699-gosqpg3k	363	44	development	development	NN
cord-263699-gosqpg3k	363	45	of	of	IN
cord-263699-gosqpg3k	363	46	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	363	47	replication	replication	NN
cord-263699-gosqpg3k	363	48	organelles	organelle	NNS
cord-263699-gosqpg3k	363	49	Coatomer	Coatomer	NNP
cord-263699-gosqpg3k	363	50	-	-	HYPH
cord-263699-gosqpg3k	363	51	dependent	dependent	JJ
cord-263699-gosqpg3k	363	52	protein	protein	NN
cord-263699-gosqpg3k	363	53	delivery	delivery	NN
cord-263699-gosqpg3k	363	54	to	to	IN
cord-263699-gosqpg3k	363	55	lipid	lipid	NN
cord-263699-gosqpg3k	363	56	droplets	droplet	NNS
cord-263699-gosqpg3k	363	57	Involvement	Involvement	NNP
cord-263699-gosqpg3k	363	58	of	of	IN
cord-263699-gosqpg3k	363	59	membrane	membrane	NN
cord-263699-gosqpg3k	363	60	traffic	traffic	NN
cord-263699-gosqpg3k	363	61	in	in	IN
cord-263699-gosqpg3k	363	62	the	the	DT
cord-263699-gosqpg3k	363	63	replication	replication	NN
cord-263699-gosqpg3k	363	64	of	of	IN
cord-263699-gosqpg3k	363	65	poliovirus	poliovirus	NN
cord-263699-gosqpg3k	363	66	genomes	genome	NNS
cord-263699-gosqpg3k	363	67	:	:	:
cord-263699-gosqpg3k	363	68	Effects	effect	NNS
cord-263699-gosqpg3k	363	69	of	of	IN
cord-263699-gosqpg3k	363	70	brefeldin	brefeldin	NNP
cord-263699-gosqpg3k	363	71	A.	a.	NN
cord-263699-gosqpg3k	363	72	Virology	Virology	NNP
cord-263699-gosqpg3k	364	1	ACBD3-mediated	acbd3-mediated	CD
cord-263699-gosqpg3k	364	2	recruitment	recruitment	NN
cord-263699-gosqpg3k	364	3	of	of	IN
cord-263699-gosqpg3k	364	4	PI4	PI4	NNP
cord-263699-gosqpg3k	364	5	KB	KB	NNP
cord-263699-gosqpg3k	364	6	to	to	IN
cord-263699-gosqpg3k	364	7	picornavirus	picornavirus	NNP
cord-263699-gosqpg3k	364	8	RNA	RNA	NNP
cord-263699-gosqpg3k	364	9	replication	replication	NN
cord-263699-gosqpg3k	364	10	sites	site	NNS
cord-263699-gosqpg3k	364	11	Fields	Fields	NNP
cord-263699-gosqpg3k	364	12	Virology	Virology	NNP
cord-263699-gosqpg3k	364	13	Spatial	Spatial	NNP
cord-263699-gosqpg3k	364	14	and	and	CC
cord-263699-gosqpg3k	364	15	temporal	temporal	JJ
cord-263699-gosqpg3k	364	16	analysis	analysis	NN
cord-263699-gosqpg3k	364	17	of	of	IN
cord-263699-gosqpg3k	364	18	alphavirus	alphavirus	NNP
cord-263699-gosqpg3k	364	19	replication	replication	NN
cord-263699-gosqpg3k	364	20	and	and	CC
cord-263699-gosqpg3k	364	21	assembly	assembly	NN
cord-263699-gosqpg3k	364	22	in	in	IN
cord-263699-gosqpg3k	364	23	mammalian	mammalian	JJ
cord-263699-gosqpg3k	364	24	and	and	CC
cord-263699-gosqpg3k	364	25	mosquito	mosquito	NN
cord-263699-gosqpg3k	364	26	cells	cell	NNS
cord-263699-gosqpg3k	364	27	Requirement	Requirement	NNP
cord-263699-gosqpg3k	364	28	of	of	IN
cord-263699-gosqpg3k	364	29	the	the	DT
cord-263699-gosqpg3k	364	30	vesicular	vesicular	JJ
cord-263699-gosqpg3k	364	31	system	system	NN
cord-263699-gosqpg3k	364	32	for	for	IN
cord-263699-gosqpg3k	364	33	membrane	membrane	NN
cord-263699-gosqpg3k	364	34	permeabilization	permeabilization	NN
cord-263699-gosqpg3k	364	35	by	by	IN
cord-263699-gosqpg3k	364	36	Sindbis	Sindbis	NNP
cord-263699-gosqpg3k	364	37	virus	virus	NN
cord-263699-gosqpg3k	364	38	Emerging	emerge	VBG
cord-263699-gosqpg3k	364	39	role	role	NN
cord-263699-gosqpg3k	364	40	of	of	IN
cord-263699-gosqpg3k	364	41	lipid	lipid	NN
cord-263699-gosqpg3k	364	42	droplets	droplet	NNS
cord-263699-gosqpg3k	364	43	in	in	IN
cord-263699-gosqpg3k	364	44	Aedes	Aedes	NNP
cord-263699-gosqpg3k	364	45	aegypti	aegypti	NN
cord-263699-gosqpg3k	364	46	immune	immune	JJ
cord-263699-gosqpg3k	364	47	response	response	NN
cord-263699-gosqpg3k	364	48	against	against	IN
cord-263699-gosqpg3k	364	49	bacteria	bacteria	NNS
cord-263699-gosqpg3k	364	50	and	and	CC
cord-263699-gosqpg3k	364	51	dengue	dengue	NN
cord-263699-gosqpg3k	364	52	virus	virus	NN
cord-263699-gosqpg3k	364	53	Hepatitis	hepatitis	NN
cord-263699-gosqpg3k	364	54	E	E	NNP
cord-263699-gosqpg3k	364	55	virus	virus	NN
cord-263699-gosqpg3k	364	56	Fields	Fields	NNP
cord-263699-gosqpg3k	364	57	Virology	Virology	NNP
cord-263699-gosqpg3k	365	1	An	an	DT
cord-263699-gosqpg3k	365	2	overview	overview	NN
cord-263699-gosqpg3k	365	3	of	of	IN
cord-263699-gosqpg3k	365	4	their	-PRON-	PRP$
cord-263699-gosqpg3k	365	5	replication	replication	NN
cord-263699-gosqpg3k	365	6	and	and	CC
cord-263699-gosqpg3k	365	7	pathogenesis	pathogenesis	NN
cord-263699-gosqpg3k	365	8	Dominant	dominant	JJ
cord-263699-gosqpg3k	365	9	inhibitory	inhibitory	JJ
cord-263699-gosqpg3k	365	10	mutants	mutant	NNS
cord-263699-gosqpg3k	365	11	of	of	IN
cord-263699-gosqpg3k	365	12	Arf1	Arf1	NNP
cord-263699-gosqpg3k	365	13	block	block	NN
cord-263699-gosqpg3k	365	14	endoplasmic	endoplasmic	NN
cord-263699-gosqpg3k	365	15	reticulum	reticulum	NN
cord-263699-gosqpg3k	365	16	to	to	IN
cord-263699-gosqpg3k	365	17	Golgi	Golgi	NNP
cord-263699-gosqpg3k	365	18	transport	transport	NN
cord-263699-gosqpg3k	365	19	and	and	CC
cord-263699-gosqpg3k	365	20	trigger	trigger	NN
cord-263699-gosqpg3k	365	21	disassembly	disassembly	NN
cord-263699-gosqpg3k	365	22	of	of	IN
cord-263699-gosqpg3k	365	23	the	the	DT
cord-263699-gosqpg3k	365	24	Golgi	Golgi	NNP
cord-263699-gosqpg3k	365	25	apparatus	apparatus	NN
cord-263699-gosqpg3k	365	26	Fields	Fields	NNP
cord-263699-gosqpg3k	365	27	Virology	Virology	NNP
cord-263699-gosqpg3k	366	1	Brefeldin	Brefeldin	NNP
cord-263699-gosqpg3k	366	2	A	A	NNP
cord-263699-gosqpg3k	367	1	blocks	block	VBZ
cord-263699-gosqpg3k	367	2	protein	protein	NN
cord-263699-gosqpg3k	367	3	glycosylation	glycosylation	NN
cord-263699-gosqpg3k	367	4	and	and	CC
cord-263699-gosqpg3k	367	5	RNA	RNA	NNP
cord-263699-gosqpg3k	367	6	replication	replication	NN
cord-263699-gosqpg3k	367	7	of	of	IN
cord-263699-gosqpg3k	367	8	vesicular	vesicular	JJ
cord-263699-gosqpg3k	367	9	stomatitis	stomatitis	NN
cord-263699-gosqpg3k	367	10	virus	virus	NN
cord-263699-gosqpg3k	367	11	Genetic	genetic	JJ
cord-263699-gosqpg3k	367	12	inactivation	inactivation	NN
cord-263699-gosqpg3k	367	13	of	of	IN
cord-263699-gosqpg3k	367	14	COPI	COPI	NNP
cord-263699-gosqpg3k	367	15	coatomer	coatomer	VBP
cord-263699-gosqpg3k	367	16	separately	separately	RB
cord-263699-gosqpg3k	367	17	inhibits	inhibit	VBZ
cord-263699-gosqpg3k	367	18	vesicular	vesicular	JJ
cord-263699-gosqpg3k	367	19	stomatitis	stomatitis	NN
cord-263699-gosqpg3k	367	20	virus	virus	NN
cord-263699-gosqpg3k	367	21	entry	entry	NN
cord-263699-gosqpg3k	367	22	and	and	CC
cord-263699-gosqpg3k	367	23	gene	gene	NN
cord-263699-gosqpg3k	367	24	expression	expression	NN
cord-263699-gosqpg3k	368	1	An	an	DT
cord-263699-gosqpg3k	368	2	outbreak	outbreak	NN
cord-263699-gosqpg3k	368	3	of	of	IN
cord-263699-gosqpg3k	368	4	Chandipura	Chandipura	NNP
cord-263699-gosqpg3k	368	5	virus	virus	NN
cord-263699-gosqpg3k	368	6	encephalitis	encephalitis	RB
cord-263699-gosqpg3k	368	7	in	in	IN
cord-263699-gosqpg3k	368	8	the	the	DT
cord-263699-gosqpg3k	368	9	eastern	eastern	JJ
cord-263699-gosqpg3k	368	10	districts	district	NNS
cord-263699-gosqpg3k	368	11	of	of	IN
cord-263699-gosqpg3k	368	12	Gujarat	Gujarat	NNP
cord-263699-gosqpg3k	368	13	state	state	NN
cord-263699-gosqpg3k	368	14	Chandipura	Chandipura	NNP
cord-263699-gosqpg3k	368	15	virus	virus	NN
cord-263699-gosqpg3k	368	16	encephalitis	encephalitis	JJ
cord-263699-gosqpg3k	368	17	outbreak	outbreak	NN
cord-263699-gosqpg3k	368	18	among	among	IN
cord-263699-gosqpg3k	368	19	children	child	NNS
cord-263699-gosqpg3k	368	20	in	in	IN
cord-263699-gosqpg3k	368	21	Nagpur	Nagpur	NNP
cord-263699-gosqpg3k	368	22	division	division	NN
cord-263699-gosqpg3k	368	23	Predicting	predict	VBG
cord-263699-gosqpg3k	368	24	the	the	DT
cord-263699-gosqpg3k	368	25	host	host	NN
cord-263699-gosqpg3k	368	26	protein	protein	NN
cord-263699-gosqpg3k	368	27	interactors	interactor	NNS
cord-263699-gosqpg3k	368	28	of	of	IN
cord-263699-gosqpg3k	368	29	Chandipura	Chandipura	NNP
cord-263699-gosqpg3k	368	30	virus	virus	NN
cord-263699-gosqpg3k	368	31	using	use	VBG
cord-263699-gosqpg3k	368	32	a	a	DT
cord-263699-gosqpg3k	368	33	structural	structural	JJ
cord-263699-gosqpg3k	368	34	similarity	similarity	NN
cord-263699-gosqpg3k	368	35	-	-	HYPH
cord-263699-gosqpg3k	368	36	based	base	VBN
cord-263699-gosqpg3k	368	37	approach	approach	NN
cord-263699-gosqpg3k	368	38	Protein	Protein	NNP
cord-263699-gosqpg3k	368	39	expression	expression	NN
cord-263699-gosqpg3k	368	40	redirects	redirect	VBZ
cord-263699-gosqpg3k	368	41	vesicular	vesicular	JJ
cord-263699-gosqpg3k	368	42	stomatitis	stomatitis	NN
cord-263699-gosqpg3k	368	43	virus	virus	NN
cord-263699-gosqpg3k	368	44	RNA	RNA	NNP
cord-263699-gosqpg3k	368	45	synthesis	synthesis	NN
cord-263699-gosqpg3k	368	46	to	to	IN
cord-263699-gosqpg3k	368	47	cytoplasmic	cytoplasmic	JJ
cord-263699-gosqpg3k	368	48	inclusions	inclusion	NNS
cord-263699-gosqpg3k	369	1	Cytoplasmic	Cytoplasmic	NNP
cord-263699-gosqpg3k	369	2	coat	coat	NN
cord-263699-gosqpg3k	369	3	proteins	protein	NNS
cord-263699-gosqpg3k	369	4	involved	involve	VBN
cord-263699-gosqpg3k	369	5	in	in	IN
cord-263699-gosqpg3k	369	6	endosome	endosome	NN
cord-263699-gosqpg3k	369	7	function	function	NN
cord-263699-gosqpg3k	370	1	Influenza	Influenza	NNP
cord-263699-gosqpg3k	370	2	A	a	DT
cord-263699-gosqpg3k	370	3	virus	virus	NN
cord-263699-gosqpg3k	370	4	cell	cell	NN
cord-263699-gosqpg3k	370	5	entry	entry	NN
cord-263699-gosqpg3k	370	6	,	,	,
cord-263699-gosqpg3k	370	7	replication	replication	NN
cord-263699-gosqpg3k	370	8	,	,	,
cord-263699-gosqpg3k	370	9	virion	virion	NN
cord-263699-gosqpg3k	370	10	assembly	assembly	NN
cord-263699-gosqpg3k	370	11	and	and	CC
cord-263699-gosqpg3k	370	12	movement	movement	NN
cord-263699-gosqpg3k	370	13	Fields	Fields	NNP
cord-263699-gosqpg3k	370	14	Virology	Virology	NNP
cord-263699-gosqpg3k	371	1	A	a	DT
cord-263699-gosqpg3k	372	1	Rab11-and	Rab11-and	NNP
cord-263699-gosqpg3k	372	2	microtubule	microtubule	NN
cord-263699-gosqpg3k	372	3	-	-	HYPH
cord-263699-gosqpg3k	372	4	dependent	dependent	JJ
cord-263699-gosqpg3k	372	5	mechanism	mechanism	NN
cord-263699-gosqpg3k	372	6	for	for	IN
cord-263699-gosqpg3k	372	7	cytoplasmic	cytoplasmic	JJ
cord-263699-gosqpg3k	372	8	transport	transport	NN
cord-263699-gosqpg3k	372	9	of	of	IN
cord-263699-gosqpg3k	372	10	influenza	influenza	NN
cord-263699-gosqpg3k	372	11	A	a	DT
cord-263699-gosqpg3k	372	12	Virus	Virus	NNP
cord-263699-gosqpg3k	372	13	viral	viral	JJ
cord-263699-gosqpg3k	372	14	RNA	RNA	NNP
cord-263699-gosqpg3k	372	15	Apical	Apical	NNP
cord-263699-gosqpg3k	372	16	transport	transport	NN
cord-263699-gosqpg3k	372	17	of	of	IN
cord-263699-gosqpg3k	372	18	influenza	influenza	NN
cord-263699-gosqpg3k	372	19	A	a	DT
cord-263699-gosqpg3k	372	20	virus	virus	NN
cord-263699-gosqpg3k	372	21	ribonucleoprotein	ribonucleoprotein	NN
cord-263699-gosqpg3k	372	22	requires	require	VBZ
cord-263699-gosqpg3k	372	23	Rab11-positive	rab11-positive	JJ
cord-263699-gosqpg3k	372	24	recycling	recycling	NN
cord-263699-gosqpg3k	372	25	endosome	endosome	NN
cord-263699-gosqpg3k	372	26	Influenza	Influenza	NNP
cord-263699-gosqpg3k	372	27	virus	virus	NN
cord-263699-gosqpg3k	372	28	genome	genome	NN
cord-263699-gosqpg3k	372	29	reaches	reach	VBZ
cord-263699-gosqpg3k	372	30	the	the	DT
cord-263699-gosqpg3k	372	31	plasma	plasma	NN
cord-263699-gosqpg3k	372	32	membrane	membrane	NN
cord-263699-gosqpg3k	372	33	via	via	IN
cord-263699-gosqpg3k	372	34	a	a	DT
cord-263699-gosqpg3k	372	35	modified	modify	VBN
cord-263699-gosqpg3k	372	36	endoplasmic	endoplasmic	NN
cord-263699-gosqpg3k	372	37	reticulum	reticulum	NN
cord-263699-gosqpg3k	372	38	and	and	CC
cord-263699-gosqpg3k	372	39	Rab11-dependent	rab11-dependent	NN
cord-263699-gosqpg3k	372	40	vesicles	vesicle	NNS
cord-263699-gosqpg3k	372	41	Involvement	Involvement	NNP
cord-263699-gosqpg3k	372	42	of	of	IN
cord-263699-gosqpg3k	372	43	vesicular	vesicular	JJ
cord-263699-gosqpg3k	372	44	trafficking	trafficking	NN
cord-263699-gosqpg3k	372	45	system	system	NN
cord-263699-gosqpg3k	372	46	in	in	IN
cord-263699-gosqpg3k	372	47	membrane	membrane	NN
cord-263699-gosqpg3k	372	48	targeting	target	VBG
cord-263699-gosqpg3k	372	49	of	of	IN
cord-263699-gosqpg3k	372	50	the	the	DT
cord-263699-gosqpg3k	372	51	progeny	progeny	NN
cord-263699-gosqpg3k	372	52	influenza	influenza	NN
cord-263699-gosqpg3k	372	53	virus	virus	NN
cord-263699-gosqpg3k	372	54	genome	genome	NN
cord-263699-gosqpg3k	372	55	.	.	.
cord-263699-gosqpg3k	373	1	Microbes	microbe	NNS
cord-263699-gosqpg3k	373	2	Infect	infect	VBP
cord-263699-gosqpg3k	374	1	Human	human	JJ
cord-263699-gosqpg3k	374	2	host	host	NN
cord-263699-gosqpg3k	374	3	factors	factor	NNS
cord-263699-gosqpg3k	374	4	required	require	VBN
cord-263699-gosqpg3k	374	5	for	for	IN
cord-263699-gosqpg3k	374	6	influenza	influenza	NN
cord-263699-gosqpg3k	374	7	virus	virus	NN
cord-263699-gosqpg3k	374	8	replication	replication	NN
cord-263699-gosqpg3k	374	9	Fields	Fields	NNP
cord-263699-gosqpg3k	374	10	Virology	Virology	NNP
cord-263699-gosqpg3k	374	11	Rotavirus	rotavirus	NN
cord-263699-gosqpg3k	374	12	Proteins	Proteins	NNPS
cord-263699-gosqpg3k	374	13	VP7	vp7	NN
cord-263699-gosqpg3k	374	14	,	,	,
cord-263699-gosqpg3k	374	15	NS28	NS28	NNP
cord-263699-gosqpg3k	374	16	,	,	,
cord-263699-gosqpg3k	374	17	and	and	CC
cord-263699-gosqpg3k	374	18	VP4	vp4	JJ
cord-263699-gosqpg3k	374	19	form	form	NN
cord-263699-gosqpg3k	374	20	oligomeric	oligomeric	JJ
cord-263699-gosqpg3k	374	21	structures	structure	NNS
cord-263699-gosqpg3k	375	1	A	a	DT
cord-263699-gosqpg3k	375	2	systems	system	NNS
cord-263699-gosqpg3k	375	3	survey	survey	NN
cord-263699-gosqpg3k	375	4	of	of	IN
cord-263699-gosqpg3k	375	5	progressive	progressive	JJ
cord-263699-gosqpg3k	375	6	host	host	NN
cord-263699-gosqpg3k	375	7	-	-	HYPH
cord-263699-gosqpg3k	375	8	cell	cell	NN
cord-263699-gosqpg3k	375	9	reorganization	reorganization	NN
cord-263699-gosqpg3k	375	10	during	during	IN
cord-263699-gosqpg3k	375	11	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	375	12	infection	infection	NN
cord-263699-gosqpg3k	375	13	Genome	Genome	NNP
cord-263699-gosqpg3k	375	14	-	-	HYPH
cord-263699-gosqpg3k	375	15	wide	wide	JJ
cord-263699-gosqpg3k	375	16	RNAi	RNAi	NNS
cord-263699-gosqpg3k	375	17	screen	screen	NN
cord-263699-gosqpg3k	375	18	reveals	reveal	VBZ
cord-263699-gosqpg3k	375	19	a	a	DT
cord-263699-gosqpg3k	375	20	role	role	NN
cord-263699-gosqpg3k	375	21	for	for	IN
cord-263699-gosqpg3k	375	22	the	the	DT
cord-263699-gosqpg3k	375	23	ESCRT	ESCRT	NNP
cord-263699-gosqpg3k	375	24	complex	complex	NN
cord-263699-gosqpg3k	375	25	in	in	IN
cord-263699-gosqpg3k	375	26	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	375	27	cell	cell	NN
cord-263699-gosqpg3k	375	28	entry	entry	NN
cord-263699-gosqpg3k	375	29	Effect	effect	NN
cord-263699-gosqpg3k	375	30	of	of	IN
cord-263699-gosqpg3k	375	31	brefeldin	brefeldin	NNS
cord-263699-gosqpg3k	375	32	A	A	NNP
cord-263699-gosqpg3k	375	33	on	on	IN
cord-263699-gosqpg3k	375	34	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	375	35	assembly	assembly	NN
cord-263699-gosqpg3k	375	36	and	and	CC
cord-263699-gosqpg3k	375	37	oligosaccharide	oligosaccharide	NN
cord-263699-gosqpg3k	375	38	processing	processing	NN
cord-263699-gosqpg3k	375	39	Dissecting	dissect	VBG
cord-263699-gosqpg3k	375	40	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	375	41	particle	particle	NN
cord-263699-gosqpg3k	375	42	-	-	HYPH
cord-263699-gosqpg3k	375	43	raft	raft	NN
cord-263699-gosqpg3k	375	44	interaction	interaction	NN
cord-263699-gosqpg3k	375	45	with	with	IN
cord-263699-gosqpg3k	375	46	small	small	JJ
cord-263699-gosqpg3k	375	47	interfering	interfere	VBG
cord-263699-gosqpg3k	375	48	RNAs	rna	NNS
cord-263699-gosqpg3k	375	49	:	:	:
cord-263699-gosqpg3k	375	50	Insights	insight	NNS
cord-263699-gosqpg3k	375	51	into	into	IN
cord-263699-gosqpg3k	375	52	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	375	53	transit	transit	NN
cord-263699-gosqpg3k	375	54	through	through	IN
cord-263699-gosqpg3k	375	55	the	the	DT
cord-263699-gosqpg3k	375	56	secretory	secretory	JJ
cord-263699-gosqpg3k	375	57	pathway	pathway	NN
cord-263699-gosqpg3k	375	58	Effects	effect	NNS
cord-263699-gosqpg3k	375	59	of	of	IN
cord-263699-gosqpg3k	375	60	tunicamycin	tunicamycin	NNS
cord-263699-gosqpg3k	375	61	on	on	IN
cord-263699-gosqpg3k	375	62	rotavirus	rotavirus	JJ
cord-263699-gosqpg3k	375	63	morphogenesis	morphogenesis	NN
cord-263699-gosqpg3k	375	64	and	and	CC
cord-263699-gosqpg3k	375	65	infectivity	infectivity	NN
cord-263699-gosqpg3k	376	1	This	this	DT
cord-263699-gosqpg3k	376	2	article	article	NN
cord-263699-gosqpg3k	376	3	is	be	VBZ
cord-263699-gosqpg3k	376	4	an	an	DT
cord-263699-gosqpg3k	376	5	open	open	JJ
cord-263699-gosqpg3k	376	6	access	access	NN
cord-263699-gosqpg3k	376	7	article	article	NN
cord-263699-gosqpg3k	376	8	distributed	distribute	VBN
cord-263699-gosqpg3k	376	9	under	under	IN
cord-263699-gosqpg3k	376	10	the	the	DT
cord-263699-gosqpg3k	376	11	terms	term	NNS
cord-263699-gosqpg3k	376	12	and	and	CC
cord-263699-gosqpg3k	376	13	conditions	condition	NNS
cord-263699-gosqpg3k	376	14	of	of	IN
cord-263699-gosqpg3k	376	15	the	the	DT
cord-263699-gosqpg3k	376	16	Creative	Creative	NNP
cord-263699-gosqpg3k	376	17	Commons	Commons	NNP
cord-263699-gosqpg3k	376	18	Attribution	Attribution	NNP
cord-263699-gosqpg3k	376	19	(	(	-LRB-
cord-263699-gosqpg3k	376	20	CC	CC	NNP
cord-263699-gosqpg3k	376	21	BY	by	IN
cord-263699-gosqpg3k	376	22	)	)	-RRB-
cord-263699-gosqpg3k	376	23	license	license	NN
cord-263699-gosqpg3k	377	1	The	the	DT
cord-263699-gosqpg3k	377	2	authors	author	NNS
cord-263699-gosqpg3k	377	3	declare	declare	VBP
cord-263699-gosqpg3k	377	4	no	no	DT
cord-263699-gosqpg3k	377	5	conflict	conflict	NN
cord-263699-gosqpg3k	377	6	of	of	IN
cord-263699-gosqpg3k	377	7	interest	interest	NN
cord-263699-gosqpg3k	377	8	.	.	.
cord-263699-gosqpg3k	378	1	The	the	DT
cord-263699-gosqpg3k	378	2	funders	funder	NNS
cord-263699-gosqpg3k	378	3	had	have	VBD
cord-263699-gosqpg3k	378	4	no	no	DT
cord-263699-gosqpg3k	378	5	role	role	NN
cord-263699-gosqpg3k	378	6	in	in	IN
cord-263699-gosqpg3k	378	7	the	the	DT
cord-263699-gosqpg3k	378	8	design	design	NN
cord-263699-gosqpg3k	378	9	of	of	IN
cord-263699-gosqpg3k	378	10	the	the	DT
cord-263699-gosqpg3k	378	11	study	study	NN
cord-263699-gosqpg3k	378	12	;	;	:
cord-263699-gosqpg3k	378	13	in	in	IN
cord-263699-gosqpg3k	378	14	the	the	DT
cord-263699-gosqpg3k	378	15	collection	collection	NN
cord-263699-gosqpg3k	378	16	,	,	,
cord-263699-gosqpg3k	378	17	analyses	analysis	NNS
cord-263699-gosqpg3k	378	18	,	,	,
cord-263699-gosqpg3k	378	19	or	or	CC
cord-263699-gosqpg3k	378	20	interpretation	interpretation	NN
cord-263699-gosqpg3k	378	21	of	of	IN
cord-263699-gosqpg3k	378	22	data	datum	NNS
cord-263699-gosqpg3k	378	23	;	;	:
cord-263699-gosqpg3k	378	24	in	in	IN
cord-263699-gosqpg3k	378	25	the	the	DT
cord-263699-gosqpg3k	378	26	writing	writing	NN
cord-263699-gosqpg3k	378	27	of	of	IN
cord-263699-gosqpg3k	378	28	the	the	DT
cord-263699-gosqpg3k	378	29	manuscript	manuscript	NN
cord-263699-gosqpg3k	378	30	,	,	,
cord-263699-gosqpg3k	378	31	or	or	CC
cord-263699-gosqpg3k	378	32	in	in	IN
cord-263699-gosqpg3k	378	33	the	the	DT
cord-263699-gosqpg3k	378	34	decision	decision	NN
cord-263699-gosqpg3k	378	35	to	to	TO
cord-263699-gosqpg3k	378	36	publish	publish	VB
cord-263699-gosqpg3k	378	37	the	the	DT
cord-263699-gosqpg3k	378	38	results	result	NNS
cord-263699-gosqpg3k	378	39	.	.	.