id	sid	tid	token	lemma	pos
cord-002808-84np9brx	1	1	key	key	NN
cord-002808-84np9brx	1	2	:	:	:
cord-002808-84np9brx	2	1	cord-002808	cord-002808	NNP
cord-002808-84np9brx	2	2	-	-	HYPH
cord-002808-84np9brx	2	3	84np9brx	84np9brx	CD
cord-002808-84np9brx	2	4	authors	author	NNS
cord-002808-84np9brx	2	5	:	:	:
cord-002808-84np9brx	2	6	Campos	Campos	NNP
cord-002808-84np9brx	2	7	,	,	,
cord-002808-84np9brx	2	8	Samuel	Samuel	NNP
cord-002808-84np9brx	2	9	K.	K.	NNP
cord-002808-84np9brx	2	10	title	title	NN
cord-002808-84np9brx	2	11	:	:	:
cord-002808-84np9brx	2	12	Subcellular	Subcellular	NNP
cord-002808-84np9brx	2	13	Trafficking	trafficking	NN
cord-002808-84np9brx	2	14	of	of	IN
cord-002808-84np9brx	2	15	the	the	DT
cord-002808-84np9brx	2	16	Papillomavirus	Papillomavirus	NNP
cord-002808-84np9brx	2	17	Genome	Genome	NNP
cord-002808-84np9brx	2	18	during	during	IN
cord-002808-84np9brx	2	19	Initial	Initial	NNP
cord-002808-84np9brx	2	20	Infection	infection	NN
cord-002808-84np9brx	2	21	:	:	:
cord-002808-84np9brx	2	22	The	the	DT
cord-002808-84np9brx	2	23	Remarkable	Remarkable	NNP
cord-002808-84np9brx	2	24	Abilities	Abilities	NNPS
cord-002808-84np9brx	2	25	of	of	IN
cord-002808-84np9brx	2	26	Minor	Minor	NNP
cord-002808-84np9brx	2	27	Capsid	Capsid	NNP
cord-002808-84np9brx	2	28	Protein	Protein	NNP
cord-002808-84np9brx	2	29	L2	L2	NNP
cord-002808-84np9brx	2	30	date	date	NN
cord-002808-84np9brx	2	31	:	:	:
cord-002808-84np9brx	2	32	2017	2017	CD
cord-002808-84np9brx	2	33	-	-	HYPH
cord-002808-84np9brx	2	34	12	12	CD
cord-002808-84np9brx	2	35	-	-	HYPH
cord-002808-84np9brx	2	36	03	03	CD
cord-002808-84np9brx	2	37	journal	journal	NN
cord-002808-84np9brx	2	38	:	:	:
cord-002808-84np9brx	3	1	Viruses	virus	NNS
cord-002808-84np9brx	3	2	DOI	DOI	NNP
cord-002808-84np9brx	3	3	:	:	:
cord-002808-84np9brx	4	1	10.3390/	10.3390/	CD
cord-002808-84np9brx	5	1	v9120370	v9120370	NNP
cord-002808-84np9brx	5	2	sha	sha	NNP
cord-002808-84np9brx	5	3	:	:	:
cord-002808-84np9brx	6	1	26f219a1d536118b973f8948cd564b53beb649fe	26f219a1d536118b973f8948cd564b53beb649fe	NNP
cord-002808-84np9brx	6	2	doc_id	doc_id	CD
cord-002808-84np9brx	6	3	:	:	:
cord-002808-84np9brx	6	4	2808	2808	CD
cord-002808-84np9brx	6	5	cord_uid	cord_uid	NNS
cord-002808-84np9brx	6	6	:	:	:
cord-002808-84np9brx	7	1	84np9brx	84np9brx	CD
cord-002808-84np9brx	8	1	Since	since	IN
cord-002808-84np9brx	8	2	2012	2012	CD
cord-002808-84np9brx	8	3	,	,	,
cord-002808-84np9brx	8	4	our	-PRON-	PRP$
cord-002808-84np9brx	8	5	understanding	understanding	NN
cord-002808-84np9brx	8	6	of	of	IN
cord-002808-84np9brx	8	7	human	human	JJ
cord-002808-84np9brx	8	8	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	8	9	(	(	-LRB-
cord-002808-84np9brx	8	10	HPV	HPV	NNP
cord-002808-84np9brx	8	11	)	)	-RRB-
cord-002808-84np9brx	8	12	subcellular	subcellular	JJ
cord-002808-84np9brx	8	13	trafficking	trafficking	NN
cord-002808-84np9brx	8	14	has	have	VBZ
cord-002808-84np9brx	8	15	undergone	undergo	VBN
cord-002808-84np9brx	8	16	a	a	DT
cord-002808-84np9brx	8	17	drastic	drastic	JJ
cord-002808-84np9brx	8	18	paradigm	paradigm	NN
cord-002808-84np9brx	8	19	shift	shift	NN
cord-002808-84np9brx	8	20	.	.	.
cord-002808-84np9brx	9	1	Work	work	NN
cord-002808-84np9brx	9	2	from	from	IN
cord-002808-84np9brx	9	3	multiple	multiple	JJ
cord-002808-84np9brx	9	4	laboratories	laboratory	NNS
cord-002808-84np9brx	9	5	has	have	VBZ
cord-002808-84np9brx	9	6	revealed	reveal	VBN
cord-002808-84np9brx	9	7	that	that	IN
cord-002808-84np9brx	9	8	HPV	HPV	NNP
cord-002808-84np9brx	9	9	has	have	VBZ
cord-002808-84np9brx	9	10	evolved	evolve	VBN
cord-002808-84np9brx	9	11	a	a	DT
cord-002808-84np9brx	9	12	unique	unique	JJ
cord-002808-84np9brx	9	13	means	mean	NNS
cord-002808-84np9brx	9	14	to	to	TO
cord-002808-84np9brx	9	15	deliver	deliver	VB
cord-002808-84np9brx	9	16	its	-PRON-	PRP$
cord-002808-84np9brx	9	17	viral	viral	JJ
cord-002808-84np9brx	9	18	genome	genome	NN
cord-002808-84np9brx	9	19	(	(	-LRB-
cord-002808-84np9brx	9	20	vDNA	vdna	RB
cord-002808-84np9brx	9	21	)	)	-RRB-
cord-002808-84np9brx	9	22	to	to	IN
cord-002808-84np9brx	9	23	the	the	DT
cord-002808-84np9brx	9	24	cell	cell	NN
cord-002808-84np9brx	9	25	nucleus	nucleus	NN
cord-002808-84np9brx	9	26	,	,	,
cord-002808-84np9brx	9	27	relying	rely	VBG
cord-002808-84np9brx	9	28	on	on	IN
cord-002808-84np9brx	9	29	myriad	myriad	JJ
cord-002808-84np9brx	9	30	host	host	NN
cord-002808-84np9brx	9	31	cell	cell	NN
cord-002808-84np9brx	9	32	proteins	protein	NNS
cord-002808-84np9brx	9	33	and	and	CC
cord-002808-84np9brx	9	34	processes	process	NNS
cord-002808-84np9brx	9	35	.	.	.
cord-002808-84np9brx	10	1	The	the	DT
cord-002808-84np9brx	10	2	major	major	JJ
cord-002808-84np9brx	10	3	breakthrough	breakthrough	NN
cord-002808-84np9brx	10	4	finding	finding	NN
cord-002808-84np9brx	10	5	from	from	IN
cord-002808-84np9brx	10	6	these	these	DT
cord-002808-84np9brx	10	7	recent	recent	JJ
cord-002808-84np9brx	10	8	endeavors	endeavor	NNS
cord-002808-84np9brx	10	9	has	have	VBZ
cord-002808-84np9brx	10	10	been	be	VBN
cord-002808-84np9brx	10	11	the	the	DT
cord-002808-84np9brx	10	12	realization	realization	NN
cord-002808-84np9brx	10	13	of	of	IN
cord-002808-84np9brx	10	14	L2-dependent	L2-dependent	NNP
cord-002808-84np9brx	10	15	utilization	utilization	NN
cord-002808-84np9brx	10	16	of	of	IN
cord-002808-84np9brx	10	17	cellular	cellular	JJ
cord-002808-84np9brx	10	18	sorting	sorting	NN
cord-002808-84np9brx	10	19	factors	factor	NNS
cord-002808-84np9brx	10	20	for	for	IN
cord-002808-84np9brx	10	21	the	the	DT
cord-002808-84np9brx	10	22	retrograde	retrograde	JJ
cord-002808-84np9brx	10	23	transport	transport	NN
cord-002808-84np9brx	10	24	of	of	IN
cord-002808-84np9brx	10	25	vDNA	vdna	RB
cord-002808-84np9brx	10	26	away	away	RB
cord-002808-84np9brx	10	27	from	from	IN
cord-002808-84np9brx	10	28	degradative	degradative	JJ
cord-002808-84np9brx	10	29	endo	endo	NNP
cord-002808-84np9brx	10	30	/	/	SYM
cord-002808-84np9brx	10	31	lysosomal	lysosomal	JJ
cord-002808-84np9brx	10	32	compartments	compartment	NNS
cord-002808-84np9brx	10	33	to	to	IN
cord-002808-84np9brx	10	34	the	the	DT
cord-002808-84np9brx	10	35	Golgi	Golgi	NNP
cord-002808-84np9brx	10	36	,	,	,
cord-002808-84np9brx	10	37	prior	prior	RB
cord-002808-84np9brx	10	38	to	to	IN
cord-002808-84np9brx	10	39	mitosis	mitosis	NN
cord-002808-84np9brx	10	40	-	-	HYPH
cord-002808-84np9brx	10	41	dependent	dependent	JJ
cord-002808-84np9brx	10	42	nuclear	nuclear	JJ
cord-002808-84np9brx	10	43	accumulation	accumulation	NN
cord-002808-84np9brx	10	44	of	of	IN
cord-002808-84np9brx	10	45	L2	L2	NNP
cord-002808-84np9brx	10	46	/	/	SYM
cord-002808-84np9brx	10	47	vDNA	vdna	NN
cord-002808-84np9brx	10	48	.	.	.
cord-002808-84np9brx	11	1	An	an	DT
cord-002808-84np9brx	11	2	overview	overview	NN
cord-002808-84np9brx	11	3	of	of	IN
cord-002808-84np9brx	11	4	current	current	JJ
cord-002808-84np9brx	11	5	models	model	NNS
cord-002808-84np9brx	11	6	of	of	IN
cord-002808-84np9brx	11	7	HPV	HPV	NNP
cord-002808-84np9brx	11	8	entry	entry	NN
cord-002808-84np9brx	11	9	,	,	,
cord-002808-84np9brx	11	10	subcellular	subcellular	JJ
cord-002808-84np9brx	11	11	trafficking	trafficking	NN
cord-002808-84np9brx	11	12	,	,	,
cord-002808-84np9brx	11	13	and	and	CC
cord-002808-84np9brx	11	14	the	the	DT
cord-002808-84np9brx	11	15	role	role	NN
cord-002808-84np9brx	11	16	of	of	IN
cord-002808-84np9brx	11	17	L2	L2	NNP
cord-002808-84np9brx	11	18	during	during	IN
cord-002808-84np9brx	11	19	initial	initial	JJ
cord-002808-84np9brx	11	20	infection	infection	NN
cord-002808-84np9brx	11	21	is	be	VBZ
cord-002808-84np9brx	11	22	provided	provide	VBN
cord-002808-84np9brx	11	23	below	below	RB
cord-002808-84np9brx	11	24	,	,	,
cord-002808-84np9brx	11	25	highlighting	highlight	VBG
cord-002808-84np9brx	11	26	unresolved	unresolved	JJ
cord-002808-84np9brx	11	27	questions	question	NNS
cord-002808-84np9brx	11	28	and	and	CC
cord-002808-84np9brx	11	29	gaps	gap	NNS
cord-002808-84np9brx	11	30	in	in	IN
cord-002808-84np9brx	11	31	knowledge	knowledge	NN
cord-002808-84np9brx	11	32	.	.	.
cord-002808-84np9brx	12	1	HPVs	hpvs	CC
cord-002808-84np9brx	12	2	infect	infect	VB
cord-002808-84np9brx	12	3	and	and	CC
cord-002808-84np9brx	12	4	replicate	replicate	VB
cord-002808-84np9brx	12	5	in	in	IN
cord-002808-84np9brx	12	6	cutaneous	cutaneous	JJ
cord-002808-84np9brx	12	7	and	and	CC
cord-002808-84np9brx	12	8	mucosal	mucosal	JJ
cord-002808-84np9brx	12	9	epithelium	epithelium	NN
cord-002808-84np9brx	12	10	(	(	-LRB-
cord-002808-84np9brx	12	11	skin	skin	NN
cord-002808-84np9brx	12	12	and	and	CC
cord-002808-84np9brx	12	13	oral	oral	JJ
cord-002808-84np9brx	12	14	/	/	SYM
cord-002808-84np9brx	12	15	genital	genital	JJ
cord-002808-84np9brx	12	16	mucosa	mucosa	NN
cord-002808-84np9brx	12	17	)	)	-RRB-
cord-002808-84np9brx	12	18	.	.	.
cord-002808-84np9brx	13	1	Of	of	IN
cord-002808-84np9brx	13	2	the	the	DT
cord-002808-84np9brx	13	3	hundreds	hundred	NNS
cord-002808-84np9brx	13	4	of	of	IN
cord-002808-84np9brx	13	5	HPV	hpv	NN
cord-002808-84np9brx	13	6	types	type	NNS
cord-002808-84np9brx	13	7	[	[	-LRB-
cord-002808-84np9brx	13	8	1	1	CD
cord-002808-84np9brx	13	9	]	]	-RRB-
cord-002808-84np9brx	13	10	[	[	-LRB-
cord-002808-84np9brx	13	11	2	2	CD
cord-002808-84np9brx	13	12	]	]	-RRB-
cord-002808-84np9brx	13	13	[	[	-LRB-
cord-002808-84np9brx	13	14	3	3	CD
cord-002808-84np9brx	13	15	]	]	-RRB-
cord-002808-84np9brx	13	16	,	,	,
cord-002808-84np9brx	13	17	a	a	DT
cord-002808-84np9brx	13	18	set	set	NN
cord-002808-84np9brx	13	19	of	of	IN
cord-002808-84np9brx	13	20	about	about	RB
cord-002808-84np9brx	13	21	15	15	CD
cord-002808-84np9brx	13	22	HPV	HPV	NNP
cord-002808-84np9brx	13	23	"	"	``
cord-002808-84np9brx	13	24	high	high	JJ
cord-002808-84np9brx	13	25	-	-	HYPH
cord-002808-84np9brx	13	26	risk	risk	NN
cord-002808-84np9brx	13	27	"	"	''
cord-002808-84np9brx	13	28	types	type	NNS
cord-002808-84np9brx	13	29	are	be	VBP
cord-002808-84np9brx	13	30	associated	associate	VBN
cord-002808-84np9brx	13	31	with	with	IN
cord-002808-84np9brx	13	32	cervical	cervical	JJ
cord-002808-84np9brx	13	33	,	,	,
cord-002808-84np9brx	13	34	anogenital	anogenital	JJ
cord-002808-84np9brx	13	35	,	,	,
cord-002808-84np9brx	13	36	and	and	CC
cord-002808-84np9brx	13	37	oropharyngeal	oropharyngeal	JJ
cord-002808-84np9brx	13	38	cancers	cancer	NNS
cord-002808-84np9brx	13	39	.	.	.
cord-002808-84np9brx	14	1	An	an	DT
cord-002808-84np9brx	14	2	additional	additional	JJ
cord-002808-84np9brx	14	3	set	set	NN
cord-002808-84np9brx	14	4	of	of	IN
cord-002808-84np9brx	14	5	"	"	``
cord-002808-84np9brx	14	6	low	low	JJ
cord-002808-84np9brx	14	7	-	-	HYPH
cord-002808-84np9brx	14	8	risk	risk	NN
cord-002808-84np9brx	14	9	"	"	``
cord-002808-84np9brx	14	10	mucosal	mucosal	JJ
cord-002808-84np9brx	14	11	types	type	NNS
cord-002808-84np9brx	14	12	cause	cause	VBP
cord-002808-84np9brx	14	13	benign	benign	JJ
cord-002808-84np9brx	14	14	anogenital	anogenital	JJ
cord-002808-84np9brx	14	15	warts	wart	NNS
cord-002808-84np9brx	14	16	.	.	.
cord-002808-84np9brx	15	1	HPVs	HPVs	NNP
cord-002808-84np9brx	15	2	are	be	VBP
cord-002808-84np9brx	15	3	currently	currently	RB
cord-002808-84np9brx	15	4	the	the	DT
cord-002808-84np9brx	15	5	most	most	RBS
cord-002808-84np9brx	15	6	common	common	JJ
cord-002808-84np9brx	15	7	sexually	sexually	RB
cord-002808-84np9brx	15	8	transmitted	transmit	VBN
cord-002808-84np9brx	15	9	infection	infection	NN
cord-002808-84np9brx	15	10	,	,	,
cord-002808-84np9brx	15	11	and	and	CC
cord-002808-84np9brx	15	12	collectively	collectively	RB
cord-002808-84np9brx	15	13	,	,	,
cord-002808-84np9brx	15	14	these	these	DT
cord-002808-84np9brx	15	15	viruses	virus	NNS
cord-002808-84np9brx	15	16	account	account	VBP
cord-002808-84np9brx	15	17	for	for	IN
cord-002808-84np9brx	15	18	5	5	CD
cord-002808-84np9brx	15	19	%	%	NN
cord-002808-84np9brx	15	20	of	of	IN
cord-002808-84np9brx	15	21	cancers	cancer	NNS
cord-002808-84np9brx	15	22	worldwide	worldwide	RB
cord-002808-84np9brx	15	23	[	[	-LRB-
cord-002808-84np9brx	15	24	4	4	CD
cord-002808-84np9brx	15	25	]	]	-RRB-
cord-002808-84np9brx	16	1	[	[	-LRB-
cord-002808-84np9brx	16	2	5	5	CD
cord-002808-84np9brx	16	3	]	]	-RRB-
cord-002808-84np9brx	16	4	[	[	-LRB-
cord-002808-84np9brx	16	5	6	6	CD
cord-002808-84np9brx	16	6	]	]	-RRB-
cord-002808-84np9brx	16	7	.	.	.
cord-002808-84np9brx	17	1	As	as	IN
cord-002808-84np9brx	17	2	for	for	IN
cord-002808-84np9brx	17	3	most	most	JJS
cord-002808-84np9brx	17	4	other	other	JJ
cord-002808-84np9brx	17	5	DNA	dna	NN
cord-002808-84np9brx	17	6	viruses	virus	NNS
cord-002808-84np9brx	17	7	,	,	,
cord-002808-84np9brx	17	8	a	a	DT
cord-002808-84np9brx	17	9	successful	successful	JJ
cord-002808-84np9brx	17	10	HPV	hpv	NN
cord-002808-84np9brx	17	11	infection	infection	NN
cord-002808-84np9brx	17	12	requires	require	VBZ
cord-002808-84np9brx	17	13	that	that	IN
cord-002808-84np9brx	17	14	the	the	DT
cord-002808-84np9brx	17	15	viral	viral	JJ
cord-002808-84np9brx	17	16	genome	genome	NN
cord-002808-84np9brx	17	17	(	(	-LRB-
cord-002808-84np9brx	17	18	vDNA	vdna	LS
cord-002808-84np9brx	17	19	)	)	-RRB-
cord-002808-84np9brx	17	20	be	be	VB
cord-002808-84np9brx	17	21	transported	transport	VBN
cord-002808-84np9brx	17	22	from	from	IN
cord-002808-84np9brx	17	23	an	an	DT
cord-002808-84np9brx	17	24	extracellular	extracellular	JJ
cord-002808-84np9brx	17	25	encapsidated	encapsidated	JJ
cord-002808-84np9brx	17	26	state	state	NN
cord-002808-84np9brx	17	27	(	(	-LRB-
cord-002808-84np9brx	17	28	i.e.	i.e.	FW
cord-002808-84np9brx	17	29	,	,	,
cord-002808-84np9brx	17	30	viral	viral	JJ
cord-002808-84np9brx	17	31	particles	particle	NNS
cord-002808-84np9brx	17	32	)	)	-RRB-
cord-002808-84np9brx	17	33	to	to	IN
cord-002808-84np9brx	17	34	a	a	DT
cord-002808-84np9brx	17	35	free	free	JJ
cord-002808-84np9brx	17	36	unencapsidated	unencapsidate	VBN
cord-002808-84np9brx	17	37	state	state	NN
cord-002808-84np9brx	17	38	within	within	IN
cord-002808-84np9brx	17	39	the	the	DT
cord-002808-84np9brx	17	40	host	host	NN
cord-002808-84np9brx	17	41	cell	cell	NN
cord-002808-84np9brx	17	42	nucleus	nucleus	NN
cord-002808-84np9brx	17	43	,	,	,
cord-002808-84np9brx	17	44	to	to	TO
cord-002808-84np9brx	17	45	allow	allow	VB
cord-002808-84np9brx	17	46	for	for	IN
cord-002808-84np9brx	17	47	viral	viral	JJ
cord-002808-84np9brx	17	48	gene	gene	NN
cord-002808-84np9brx	17	49	expression	expression	NN
cord-002808-84np9brx	17	50	and	and	CC
cord-002808-84np9brx	17	51	vDNA	vdna	IN
cord-002808-84np9brx	17	52	replication	replication	NN
cord-002808-84np9brx	17	53	.	.	.
cord-002808-84np9brx	18	1	The	the	DT
cord-002808-84np9brx	18	2	non	non	JJ
cord-002808-84np9brx	18	3	-	-	JJ
cord-002808-84np9brx	18	4	enveloped	enveloped	JJ
cord-002808-84np9brx	18	5	HPV	HPV	NNP
cord-002808-84np9brx	18	6	capsid	capsid	NN
cord-002808-84np9brx	18	7	,	,	,
cord-002808-84np9brx	18	8	comprised	comprise	VBN
cord-002808-84np9brx	18	9	of	of	IN
cord-002808-84np9brx	18	10	two	two	CD
cord-002808-84np9brx	18	11	proteins	protein	NNS
cord-002808-84np9brx	18	12	(	(	-LRB-
cord-002808-84np9brx	18	13	L1	L1	NNP
cord-002808-84np9brx	18	14	and	and	CC
cord-002808-84np9brx	18	15	L2	L2	NNP
cord-002808-84np9brx	18	16	)	)	-RRB-
cord-002808-84np9brx	18	17	,	,	,
cord-002808-84np9brx	18	18	is	be	VBZ
cord-002808-84np9brx	18	19	the	the	DT
cord-002808-84np9brx	18	20	molecular	molecular	JJ
cord-002808-84np9brx	18	21	machine	machine	NN
cord-002808-84np9brx	18	22	that	that	WDT
cord-002808-84np9brx	18	23	accomplishes	accomplish	VBZ
cord-002808-84np9brx	18	24	this	this	DT
cord-002808-84np9brx	18	25	task	task	NN
cord-002808-84np9brx	18	26	.	.	.
cord-002808-84np9brx	19	1	Seventy	seventy	CD
cord-002808-84np9brx	19	2	-	-	HYPH
cord-002808-84np9brx	19	3	two	two	CD
cord-002808-84np9brx	19	4	pentamers	pentamer	NNS
cord-002808-84np9brx	19	5	of	of	IN
cord-002808-84np9brx	19	6	the	the	DT
cord-002808-84np9brx	19	7	major	major	JJ
cord-002808-84np9brx	19	8	capsid	capsid	NN
cord-002808-84np9brx	19	9	protein	protein	NN
cord-002808-84np9brx	19	10	L1	L1	NNP
cord-002808-84np9brx	19	11	form	form	NN
cord-002808-84np9brx	19	12	the	the	DT
cord-002808-84np9brx	19	13	55	55	CD
cord-002808-84np9brx	19	14	nm	nm	NN
cord-002808-84np9brx	19	15	icosahedral	icosahedral	JJ
cord-002808-84np9brx	19	16	particle	particle	NN
cord-002808-84np9brx	19	17	,	,	,
cord-002808-84np9brx	19	18	which	which	WDT
cord-002808-84np9brx	19	19	together	together	RB
cord-002808-84np9brx	19	20	with	with	IN
cord-002808-84np9brx	19	21	L2	L2	NNP
cord-002808-84np9brx	19	22	,	,	,
cord-002808-84np9brx	19	23	encapsidate	encapsidate	NNP
cord-002808-84np9brx	19	24	the	the	DT
cord-002808-84np9brx	19	25	vDNA	vdna	NN
cord-002808-84np9brx	19	26	.	.	.
cord-002808-84np9brx	20	1	The	the	DT
cord-002808-84np9brx	20	2	minor	minor	JJ
cord-002808-84np9brx	20	3	capsid	capsid	NN
cord-002808-84np9brx	20	4	protein	protein	NN
cord-002808-84np9brx	20	5	L2	L2	NNP
cord-002808-84np9brx	20	6	is	be	VBZ
cord-002808-84np9brx	20	7	present	present	JJ
cord-002808-84np9brx	20	8	in	in	IN
cord-002808-84np9brx	20	9	variable	variable	NN
cord-002808-84np9brx	20	10	,	,	,
cord-002808-84np9brx	20	11	but	but	CC
cord-002808-84np9brx	20	12	low	low	JJ
cord-002808-84np9brx	20	13	,	,	,
cord-002808-84np9brx	20	14	amounts	amount	VBZ
cord-002808-84np9brx	20	15	,	,	,
cord-002808-84np9brx	20	16	with	with	IN
cord-002808-84np9brx	20	17	a	a	DT
cord-002808-84np9brx	20	18	maximal	maximal	JJ
cord-002808-84np9brx	20	19	occupancy	occupancy	NN
cord-002808-84np9brx	20	20	of	of	IN
cord-002808-84np9brx	20	21	72	72	CD
cord-002808-84np9brx	20	22	molecules	molecule	NNS
cord-002808-84np9brx	20	23	per	per	IN
cord-002808-84np9brx	20	24	virion	virion	NN
cord-002808-84np9brx	20	25	[	[	-LRB-
cord-002808-84np9brx	20	26	7	7	CD
cord-002808-84np9brx	20	27	]	]	-RRB-
cord-002808-84np9brx	20	28	.	.	.
cord-002808-84np9brx	21	1	Most	Most	JJS
cord-002808-84np9brx	21	2	studies	study	NNS
cord-002808-84np9brx	21	3	report	report	VBP
cord-002808-84np9brx	21	4	a	a	DT
cord-002808-84np9brx	21	5	range	range	NN
cord-002808-84np9brx	21	6	between	between	IN
cord-002808-84np9brx	21	7	12	12	CD
cord-002808-84np9brx	21	8	and	and	CC
cord-002808-84np9brx	21	9	60	60	CD
cord-002808-84np9brx	21	10	molecules	molecule	NNS
cord-002808-84np9brx	21	11	of	of	IN
cord-002808-84np9brx	21	12	L2	l2	NN
cord-002808-84np9brx	21	13	per	per	IN
cord-002808-84np9brx	21	14	virion	virion	NN
cord-002808-84np9brx	21	15	[	[	-LRB-
cord-002808-84np9brx	21	16	7	7	CD
cord-002808-84np9brx	21	17	,	,	,
cord-002808-84np9brx	21	18	8	8	CD
cord-002808-84np9brx	21	19	]	]	-RRB-
cord-002808-84np9brx	21	20	,	,	,
cord-002808-84np9brx	21	21	and	and	CC
cord-002808-84np9brx	21	22	my	-PRON-	PRP$
cord-002808-84np9brx	21	23	lab	lab	NN
cord-002808-84np9brx	21	24	generally	generally	RB
cord-002808-84np9brx	21	25	estimates	estimate	VBZ
cord-002808-84np9brx	21	26	20	20	CD
cord-002808-84np9brx	21	27	-	-	SYM
cord-002808-84np9brx	21	28	40	40	CD
cord-002808-84np9brx	21	29	copies	copy	NNS
cord-002808-84np9brx	21	30	of	of	IN
cord-002808-84np9brx	21	31	L2	l2	NN
cord-002808-84np9brx	21	32	per	per	IN
cord-002808-84np9brx	21	33	particle	particle	NN
cord-002808-84np9brx	21	34	as	as	IN
cord-002808-84np9brx	21	35	measured	measure	VBN
cord-002808-84np9brx	21	36	by	by	IN
cord-002808-84np9brx	21	37	Coomassie	Coomassie	NNP
cord-002808-84np9brx	21	38	staining	staining	NN
cord-002808-84np9brx	21	39	of	of	IN
cord-002808-84np9brx	21	40	SDS	sds	NN
cord-002808-84np9brx	21	41	-	-	HYPH
cord-002808-84np9brx	21	42	PAGE	PAGE	NNP
cord-002808-84np9brx	21	43	gels	gel	NNS
cord-002808-84np9brx	21	44	and	and	CC
cord-002808-84np9brx	21	45	densitometry	densitometry	NN
cord-002808-84np9brx	21	46	.	.	.
cord-002808-84np9brx	22	1	Although	although	IN
cord-002808-84np9brx	22	2	CryoEM	CryoEM	NNP
cord-002808-84np9brx	22	3	reconstructions	reconstruction	NNS
cord-002808-84np9brx	22	4	indicate	indicate	VBP
cord-002808-84np9brx	22	5	that	that	IN
cord-002808-84np9brx	22	6	the	the	DT
cord-002808-84np9brx	22	7	bulk	bulk	NN
cord-002808-84np9brx	22	8	of	of	IN
cord-002808-84np9brx	22	9	L2	l2	NN
cord-002808-84np9brx	22	10	density	density	NN
cord-002808-84np9brx	22	11	resides	reside	VBZ
cord-002808-84np9brx	22	12	beneath	beneath	IN
cord-002808-84np9brx	22	13	the	the	DT
cord-002808-84np9brx	22	14	capsid	capsid	NN
cord-002808-84np9brx	22	15	surface	surface	NN
cord-002808-84np9brx	22	16	underneath	underneath	IN
cord-002808-84np9brx	22	17	the	the	DT
cord-002808-84np9brx	22	18	L1	L1	NNP
cord-002808-84np9brx	22	19	pentamers	pentamer	NNS
cord-002808-84np9brx	22	20	[	[	-LRB-
cord-002808-84np9brx	22	21	7	7	CD
cord-002808-84np9brx	22	22	]	]	-RRB-
cord-002808-84np9brx	22	23	,	,	,
cord-002808-84np9brx	22	24	it	-PRON-	PRP
cord-002808-84np9brx	22	25	is	be	VBZ
cord-002808-84np9brx	22	26	important	important	JJ
cord-002808-84np9brx	22	27	to	to	TO
cord-002808-84np9brx	22	28	remember	remember	VB
cord-002808-84np9brx	22	29	that	that	IN
cord-002808-84np9brx	22	30	regions	region	NNS
cord-002808-84np9brx	22	31	of	of	IN
cord-002808-84np9brx	22	32	L2	L2	NNP
cord-002808-84np9brx	22	33	are	be	VBP
cord-002808-84np9brx	22	34	known	know	VBN
cord-002808-84np9brx	22	35	to	to	TO
cord-002808-84np9brx	22	36	be	be	VB
cord-002808-84np9brx	22	37	exposed	expose	VBN
cord-002808-84np9brx	22	38	on	on	IN
cord-002808-84np9brx	22	39	the	the	DT
cord-002808-84np9brx	22	40	surface	surface	NN
cord-002808-84np9brx	22	41	of	of	IN
cord-002808-84np9brx	22	42	the	the	DT
cord-002808-84np9brx	22	43	virion	virion	NN
cord-002808-84np9brx	22	44	[	[	-LRB-
cord-002808-84np9brx	22	45	8	8	CD
cord-002808-84np9brx	22	46	]	]	-RRB-
cord-002808-84np9brx	22	47	[	[	-LRB-
cord-002808-84np9brx	22	48	9	9	CD
cord-002808-84np9brx	22	49	]	]	-RRB-
cord-002808-84np9brx	22	50	[	[	-LRB-
cord-002808-84np9brx	22	51	10	10	CD
cord-002808-84np9brx	22	52	]	]	-RRB-
cord-002808-84np9brx	22	53	.	.	.
cord-002808-84np9brx	23	1	Likewise	likewise	RB
cord-002808-84np9brx	23	2	,	,	,
cord-002808-84np9brx	23	3	it	-PRON-	PRP
cord-002808-84np9brx	23	4	is	be	VBZ
cord-002808-84np9brx	23	5	important	important	JJ
cord-002808-84np9brx	23	6	to	to	TO
cord-002808-84np9brx	23	7	consider	consider	VB
cord-002808-84np9brx	23	8	that	that	DT
cord-002808-84np9brx	23	9	individual	individual	JJ
cord-002808-84np9brx	23	10	L2	l2	NN
cord-002808-84np9brx	23	11	molecules	molecule	NNS
cord-002808-84np9brx	23	12	can	can	MD
cord-002808-84np9brx	23	13	likely	likely	RB
cord-002808-84np9brx	23	14	assume	assume	VB
cord-002808-84np9brx	23	15	different	different	JJ
cord-002808-84np9brx	23	16	conformations	conformation	NNS
cord-002808-84np9brx	23	17	or	or	CC
cord-002808-84np9brx	23	18	configurations	configuration	NNS
cord-002808-84np9brx	23	19	within	within	IN
cord-002808-84np9brx	23	20	the	the	DT
cord-002808-84np9brx	23	21	virion	virion	NN
cord-002808-84np9brx	23	22	,	,	,
cord-002808-84np9brx	23	23	although	although	IN
cord-002808-84np9brx	23	24	this	this	DT
cord-002808-84np9brx	23	25	has	have	VBZ
cord-002808-84np9brx	23	26	yet	yet	RB
cord-002808-84np9brx	23	27	to	to	TO
cord-002808-84np9brx	23	28	be	be	VB
cord-002808-84np9brx	23	29	proven	prove	VBN
cord-002808-84np9brx	23	30	.	.	.
cord-002808-84np9brx	24	1	It	-PRON-	PRP
cord-002808-84np9brx	24	2	should	should	MD
cord-002808-84np9brx	24	3	be	be	VB
cord-002808-84np9brx	24	4	noted	note	VBN
cord-002808-84np9brx	24	5	that	that	IN
cord-002808-84np9brx	24	6	many	many	JJ
cord-002808-84np9brx	24	7	of	of	IN
cord-002808-84np9brx	24	8	the	the	DT
cord-002808-84np9brx	24	9	findings	finding	NNS
cord-002808-84np9brx	24	10	summarized	summarize	VBN
cord-002808-84np9brx	24	11	in	in	IN
cord-002808-84np9brx	24	12	this	this	DT
cord-002808-84np9brx	24	13	review	review	NN
cord-002808-84np9brx	24	14	were	be	VBD
cord-002808-84np9brx	24	15	found	find	VBN
cord-002808-84np9brx	24	16	using	use	VBG
cord-002808-84np9brx	24	17	differentiation	differentiation	NN
cord-002808-84np9brx	24	18	-	-	HYPH
cord-002808-84np9brx	24	19	independent	independent	JJ
cord-002808-84np9brx	24	20	pseudovirus	pseudovirus	NN
cord-002808-84np9brx	24	21	(	(	-LRB-
cord-002808-84np9brx	24	22	PsV	PsV	NNP
cord-002808-84np9brx	24	23	)	)	-RRB-
cord-002808-84np9brx	24	24	or	or	CC
cord-002808-84np9brx	24	25	quasivirus	quasivirus	NNP
cord-002808-84np9brx	24	26	(	(	-LRB-
cord-002808-84np9brx	24	27	QsV	QsV	NNP
cord-002808-84np9brx	24	28	)	)	-RRB-
cord-002808-84np9brx	24	29	systems	system	NNS
cord-002808-84np9brx	24	30	for	for	IN
cord-002808-84np9brx	24	31	generating	generate	VBG
cord-002808-84np9brx	24	32	infectious	infectious	JJ
cord-002808-84np9brx	24	33	or	or	CC
cord-002808-84np9brx	24	34	reporter	reporter	NN
cord-002808-84np9brx	24	35	-	-	HYPH
cord-002808-84np9brx	24	36	containing	contain	VBG
cord-002808-84np9brx	24	37	HPV	hpv	NN
cord-002808-84np9brx	24	38	virions	virion	NNS
cord-002808-84np9brx	24	39	in	in	IN
cord-002808-84np9brx	24	40	293TT	293TT	NNP
cord-002808-84np9brx	24	41	cells	cell	NNS
cord-002808-84np9brx	24	42	[	[	-LRB-
cord-002808-84np9brx	24	43	16	16	CD
cord-002808-84np9brx	24	44	]	]	-RRB-
cord-002808-84np9brx	24	45	.	.	.
cord-002808-84np9brx	25	1	While	while	IN
cord-002808-84np9brx	25	2	more	more	JJR
cord-002808-84np9brx	25	3	"	"	``
cord-002808-84np9brx	25	4	native	native	JJ
cord-002808-84np9brx	25	5	"	"	''
cord-002808-84np9brx	25	6	systems	system	NNS
cord-002808-84np9brx	25	7	for	for	IN
cord-002808-84np9brx	25	8	the	the	DT
cord-002808-84np9brx	25	9	generation	generation	NN
cord-002808-84np9brx	25	10	of	of	IN
cord-002808-84np9brx	25	11	HPV	HPV	NNP
cord-002808-84np9brx	25	12	virions	virion	NNS
cord-002808-84np9brx	25	13	like	like	IN
cord-002808-84np9brx	25	14	organotypic	organotypic	JJ
cord-002808-84np9brx	25	15	raft	raft	NN
cord-002808-84np9brx	25	16	systems	system	NNS
cord-002808-84np9brx	25	17	might	may	MD
cord-002808-84np9brx	25	18	be	be	VB
cord-002808-84np9brx	25	19	ideal	ideal	JJ
cord-002808-84np9brx	25	20	,	,	,
cord-002808-84np9brx	25	21	the	the	DT
cord-002808-84np9brx	25	22	293TT	293TT	NNP
cord-002808-84np9brx	25	23	PsV	psv	NN
cord-002808-84np9brx	25	24	/	/	SYM
cord-002808-84np9brx	25	25	QsV	qsv	NN
cord-002808-84np9brx	25	26	system	system	NN
cord-002808-84np9brx	25	27	has	have	VBZ
cord-002808-84np9brx	25	28	been	be	VBN
cord-002808-84np9brx	25	29	invaluable	invaluable	JJ
cord-002808-84np9brx	25	30	for	for	IN
cord-002808-84np9brx	25	31	basic	basic	JJ
cord-002808-84np9brx	25	32	research	research	NN
cord-002808-84np9brx	25	33	on	on	IN
cord-002808-84np9brx	25	34	HPV	HPV	NNP
cord-002808-84np9brx	25	35	,	,	,
cord-002808-84np9brx	25	36	as	as	IN
cord-002808-84np9brx	25	37	the	the	DT
cord-002808-84np9brx	25	38	system	system	NN
cord-002808-84np9brx	25	39	enables	enable	VBZ
cord-002808-84np9brx	25	40	high	high	JJ
cord-002808-84np9brx	25	41	titer	titer	NN
cord-002808-84np9brx	25	42	production	production	NN
cord-002808-84np9brx	25	43	of	of	IN
cord-002808-84np9brx	25	44	highly	highly	RB
cord-002808-84np9brx	25	45	purified	purify	VBN
cord-002808-84np9brx	25	46	infectious	infectious	JJ
cord-002808-84np9brx	25	47	particles	particle	NNS
cord-002808-84np9brx	25	48	,	,	,
cord-002808-84np9brx	25	49	as	as	RB
cord-002808-84np9brx	25	50	well	well	RB
cord-002808-84np9brx	25	51	as	as	IN
cord-002808-84np9brx	25	52	the	the	DT
cord-002808-84np9brx	25	53	means	mean	NNS
cord-002808-84np9brx	25	54	to	to	TO
cord-002808-84np9brx	25	55	generate	generate	VB
cord-002808-84np9brx	25	56	virions	virion	NNS
cord-002808-84np9brx	25	57	that	that	WDT
cord-002808-84np9brx	25	58	package	package	NN
cord-002808-84np9brx	25	59	L2	l2	NN
cord-002808-84np9brx	25	60	fusions	fusion	NNS
cord-002808-84np9brx	25	61	,	,	,
cord-002808-84np9brx	25	62	noninfectious	noninfectious	JJ
cord-002808-84np9brx	25	63	L2	L2	NNP
cord-002808-84np9brx	25	64	mutants	mutant	NNS
cord-002808-84np9brx	25	65	,	,	,
cord-002808-84np9brx	25	66	and	and	CC
cord-002808-84np9brx	25	67	5-ethynyl-2′-deoxyuridine	5-ethynyl-2′-deoxyuridine	LS
cord-002808-84np9brx	25	68	(	(	-LRB-
cord-002808-84np9brx	25	69	EdU)-labeled	edu)-labele	VBN
cord-002808-84np9brx	25	70	vDNA	vdna	NN
cord-002808-84np9brx	25	71	for	for	IN
cord-002808-84np9brx	25	72	a	a	DT
cord-002808-84np9brx	25	73	variety	variety	NN
cord-002808-84np9brx	25	74	of	of	IN
cord-002808-84np9brx	25	75	experimental	experimental	JJ
cord-002808-84np9brx	25	76	systems	system	NNS
cord-002808-84np9brx	25	77	.	.	.
cord-002808-84np9brx	26	1	For	for	IN
cord-002808-84np9brx	26	2	a	a	DT
cord-002808-84np9brx	26	3	recent	recent	JJ
cord-002808-84np9brx	26	4	review	review	NN
cord-002808-84np9brx	26	5	on	on	IN
cord-002808-84np9brx	26	6	the	the	DT
cord-002808-84np9brx	26	7	differences	difference	NNS
cord-002808-84np9brx	26	8	between	between	IN
cord-002808-84np9brx	26	9	PsV	psv	NN
cord-002808-84np9brx	26	10	/	/	SYM
cord-002808-84np9brx	26	11	QsV	qsv	NN
cord-002808-84np9brx	26	12	and	and	CC
cord-002808-84np9brx	26	13	raft	raft	NN
cord-002808-84np9brx	26	14	-	-	HYPH
cord-002808-84np9brx	26	15	derived	derive	VBN
cord-002808-84np9brx	26	16	HPV	hpv	NN
cord-002808-84np9brx	26	17	,	,	,
cord-002808-84np9brx	26	18	see	see	VB
cord-002808-84np9brx	26	19	[	[	-LRB-
cord-002808-84np9brx	26	20	17	17	CD
cord-002808-84np9brx	26	21	]	]	-RRB-
cord-002808-84np9brx	26	22	.	.	.
cord-002808-84np9brx	27	1	Virion	virion	NN
cord-002808-84np9brx	27	2	binding	bind	VBG
cord-002808-84np9brx	27	3	to	to	IN
cord-002808-84np9brx	27	4	extracellular	extracellular	JJ
cord-002808-84np9brx	27	5	heparin	heparin	NN
cord-002808-84np9brx	27	6	sulfate	sulfate	NN
cord-002808-84np9brx	27	7	proteoglycans	proteoglycan	NNS
cord-002808-84np9brx	27	8	(	(	-LRB-
cord-002808-84np9brx	27	9	HSPGs	hspg	NNS
cord-002808-84np9brx	27	10	)	)	-RRB-
cord-002808-84np9brx	27	11	induces	induce	VBZ
cord-002808-84np9brx	27	12	conformational	conformational	JJ
cord-002808-84np9brx	27	13	changes	change	NNS
cord-002808-84np9brx	27	14	in	in	IN
cord-002808-84np9brx	27	15	both	both	CC
cord-002808-84np9brx	27	16	the	the	DT
cord-002808-84np9brx	27	17	L1	L1	NNP
cord-002808-84np9brx	27	18	and	and	CC
cord-002808-84np9brx	27	19	L2	L2	NNP
cord-002808-84np9brx	27	20	capsid	capsid	NN
cord-002808-84np9brx	27	21	proteins	protein	NNS
cord-002808-84np9brx	27	22	of	of	IN
cord-002808-84np9brx	27	23	the	the	DT
cord-002808-84np9brx	27	24	viral	viral	JJ
cord-002808-84np9brx	27	25	particle	particle	NN
cord-002808-84np9brx	27	26	,	,	,
cord-002808-84np9brx	27	27	and	and	CC
cord-002808-84np9brx	27	28	subsequent	subsequent	JJ
cord-002808-84np9brx	27	29	transfer	transfer	NN
cord-002808-84np9brx	27	30	of	of	IN
cord-002808-84np9brx	27	31	the	the	DT
cord-002808-84np9brx	27	32	virion	virion	NN
cord-002808-84np9brx	27	33	to	to	IN
cord-002808-84np9brx	27	34	a	a	DT
cord-002808-84np9brx	27	35	cell	cell	NN
cord-002808-84np9brx	27	36	surface	surface	NN
cord-002808-84np9brx	27	37	entry	entry	NN
cord-002808-84np9brx	27	38	receptor	receptor	NN
cord-002808-84np9brx	27	39	complex	complex	NN
cord-002808-84np9brx	27	40	[	[	-LRB-
cord-002808-84np9brx	27	41	18	18	CD
cord-002808-84np9brx	27	42	]	]	-RRB-
cord-002808-84np9brx	27	43	[	[	-LRB-
cord-002808-84np9brx	27	44	19	19	CD
cord-002808-84np9brx	27	45	]	]	-RRB-
cord-002808-84np9brx	27	46	[	[	-LRB-
cord-002808-84np9brx	27	47	20	20	CD
cord-002808-84np9brx	27	48	]	]	-RRB-
cord-002808-84np9brx	27	49	.	.	.
cord-002808-84np9brx	28	1	While	while	IN
cord-002808-84np9brx	28	2	bound	bind	VBN
cord-002808-84np9brx	28	3	,	,	,
cord-002808-84np9brx	28	4	cell	cell	NN
cord-002808-84np9brx	28	5	surface	surface	NN
cord-002808-84np9brx	28	6	kallekrein-8	kallekrein-8	NNP
cord-002808-84np9brx	28	7	(	(	-LRB-
cord-002808-84np9brx	28	8	KLK8	KLK8	NNP
cord-002808-84np9brx	28	9	)	)	-RRB-
cord-002808-84np9brx	28	10	and	and	CC
cord-002808-84np9brx	28	11	furin	furin	NN
cord-002808-84np9brx	28	12	cleave	cleave	VB
cord-002808-84np9brx	28	13	the	the	DT
cord-002808-84np9brx	28	14	L1	L1	NNP
cord-002808-84np9brx	28	15	and	and	CC
cord-002808-84np9brx	28	16	L2	L2	NNP
cord-002808-84np9brx	28	17	capsids	capsid	NNS
cord-002808-84np9brx	28	18	,	,	,
cord-002808-84np9brx	28	19	respectively	respectively	RB
cord-002808-84np9brx	28	20	,	,	,
cord-002808-84np9brx	28	21	an	an	DT
cord-002808-84np9brx	28	22	important	important	JJ
cord-002808-84np9brx	28	23	"	"	``
cord-002808-84np9brx	28	24	priming	prime	VBG
cord-002808-84np9brx	28	25	"	"	''
cord-002808-84np9brx	28	26	event	event	NN
cord-002808-84np9brx	28	27	that	that	WDT
cord-002808-84np9brx	28	28	ensures	ensure	VBZ
cord-002808-84np9brx	28	29	the	the	DT
cord-002808-84np9brx	28	30	proper	proper	JJ
cord-002808-84np9brx	28	31	subsequent	subsequent	JJ
cord-002808-84np9brx	28	32	subcellular	subcellular	JJ
cord-002808-84np9brx	28	33	trafficking	trafficking	NN
cord-002808-84np9brx	28	34	of	of	IN
cord-002808-84np9brx	28	35	L2	l2	NN
cord-002808-84np9brx	28	36	/	/	,
cord-002808-84np9brx	28	37	vDNA	vdna	NN
cord-002808-84np9brx	28	38	[	[	-LRB-
cord-002808-84np9brx	28	39	21	21	CD
cord-002808-84np9brx	28	40	]	]	-RRB-
cord-002808-84np9brx	28	41	[	[	-LRB-
cord-002808-84np9brx	28	42	22	22	CD
cord-002808-84np9brx	28	43	]	]	-RRB-
cord-002808-84np9brx	28	44	[	[	-LRB-
cord-002808-84np9brx	28	45	23	23	CD
cord-002808-84np9brx	28	46	]	]	-RRB-
cord-002808-84np9brx	28	47	.	.	.
cord-002808-84np9brx	29	1	Endocytosis	endocytosis	NN
cord-002808-84np9brx	29	2	of	of	IN
cord-002808-84np9brx	29	3	the	the	DT
cord-002808-84np9brx	29	4	virion	virion	NN
cord-002808-84np9brx	29	5	occurs	occur	VBZ
cord-002808-84np9brx	29	6	through	through	IN
cord-002808-84np9brx	29	7	an	an	DT
cord-002808-84np9brx	29	8	actin	actin	NN
cord-002808-84np9brx	29	9	-	-	HYPH
cord-002808-84np9brx	29	10	dependent	dependent	JJ
cord-002808-84np9brx	29	11	process	process	NN
cord-002808-84np9brx	29	12	with	with	IN
cord-002808-84np9brx	29	13	similarities	similarity	NNS
cord-002808-84np9brx	29	14	to	to	IN
cord-002808-84np9brx	29	15	macropinocytosis	macropinocytosis	NNP
cord-002808-84np9brx	29	16	[	[	-LRB-
cord-002808-84np9brx	29	17	24	24	CD
cord-002808-84np9brx	29	18	]	]	-RRB-
cord-002808-84np9brx	29	19	.	.	.
cord-002808-84np9brx	30	1	Tetraspanin	Tetraspanin	NNP
cord-002808-84np9brx	30	2	CD151	CD151	NNP
cord-002808-84np9brx	31	1	and	and	CC
cord-002808-84np9brx	31	2	its	-PRON-	PRP$
cord-002808-84np9brx	31	3	associated	associate	VBN
cord-002808-84np9brx	31	4	α3β1	α3β1	NNP
cord-002808-84np9brx	31	5	,	,	,
cord-002808-84np9brx	31	6	α6β1	α6β1	NNP
cord-002808-84np9brx	31	7	and	and	CC
cord-002808-84np9brx	31	8	α6β4	α6β4	VBG
cord-002808-84np9brx	31	9	integrin	integrin	JJ
cord-002808-84np9brx	31	10	partners	partner	NNS
cord-002808-84np9brx	31	11	,	,	,
cord-002808-84np9brx	31	12	growth	growth	NN
cord-002808-84np9brx	31	13	factor	factor	NN
cord-002808-84np9brx	31	14	receptor	receptor	NN
cord-002808-84np9brx	31	15	tyrosine	tyrosine	NN
cord-002808-84np9brx	31	16	kinases	kinase	NNS
cord-002808-84np9brx	31	17	,	,	,
cord-002808-84np9brx	31	18	annexin	annexin	NNP
cord-002808-84np9brx	31	19	A2	A2	NNP
cord-002808-84np9brx	31	20	,	,	,
cord-002808-84np9brx	31	21	and	and	CC
cord-002808-84np9brx	31	22	the	the	DT
cord-002808-84np9brx	31	23	cytoskeletal	cytoskeletal	JJ
cord-002808-84np9brx	31	24	adaptor	adaptor	NN
cord-002808-84np9brx	31	25	obscurin	obscurin	NN
cord-002808-84np9brx	31	26	-	-	HYPH
cord-002808-84np9brx	31	27	like	like	JJ
cord-002808-84np9brx	31	28	1	1	CD
cord-002808-84np9brx	32	1	(	(	-LRB-
cord-002808-84np9brx	32	2	OBSL1	OBSL1	NNP
cord-002808-84np9brx	32	3	)	)	-RRB-
cord-002808-84np9brx	32	4	have	have	VBP
cord-002808-84np9brx	32	5	been	be	VBN
cord-002808-84np9brx	32	6	implicated	implicate	VBN
cord-002808-84np9brx	32	7	in	in	IN
cord-002808-84np9brx	32	8	tetraspanin	tetraspanin	NN
cord-002808-84np9brx	32	9	-	-	HYPH
cord-002808-84np9brx	32	10	enriched	enrich	VBN
cord-002808-84np9brx	32	11	microdomain	microdomain	NN
cord-002808-84np9brx	32	12	(	(	-LRB-
cord-002808-84np9brx	32	13	TEM)-dependent	tem)-dependent	NN
cord-002808-84np9brx	32	14	HPV16	hpv16	NN
cord-002808-84np9brx	32	15	entry	entry	NN
cord-002808-84np9brx	32	16	[	[	-LRB-
cord-002808-84np9brx	32	17	25	25	CD
cord-002808-84np9brx	32	18	]	]	-RRB-
cord-002808-84np9brx	32	19	[	[	-LRB-
cord-002808-84np9brx	32	20	26	26	CD
cord-002808-84np9brx	32	21	]	]	-RRB-
cord-002808-84np9brx	32	22	[	[	-LRB-
cord-002808-84np9brx	32	23	27	27	CD
cord-002808-84np9brx	32	24	]	]	-RRB-
cord-002808-84np9brx	32	25	[	[	-LRB-
cord-002808-84np9brx	32	26	28	28	CD
cord-002808-84np9brx	32	27	]	]	-RRB-
cord-002808-84np9brx	32	28	[	[	-LRB-
cord-002808-84np9brx	32	29	29	29	CD
cord-002808-84np9brx	32	30	]	]	-RRB-
cord-002808-84np9brx	32	31	[	[	-LRB-
cord-002808-84np9brx	32	32	30	30	CD
cord-002808-84np9brx	32	33	]	]	-RRB-
cord-002808-84np9brx	32	34	[	[	-LRB-
cord-002808-84np9brx	32	35	31	31	CD
cord-002808-84np9brx	32	36	]	]	-RRB-
cord-002808-84np9brx	33	1	[	[	-LRB-
cord-002808-84np9brx	33	2	32	32	CD
cord-002808-84np9brx	33	3	]	]	-RRB-
cord-002808-84np9brx	34	1	(	(	-LRB-
cord-002808-84np9brx	34	2	Figure	figure	NN
cord-002808-84np9brx	34	3	2	2	CD
cord-002808-84np9brx	34	4	)	)	-RRB-
cord-002808-84np9brx	34	5	.	.	.
cord-002808-84np9brx	35	1	While	while	IN
cord-002808-84np9brx	35	2	endocytosis	endocytosis	NN
cord-002808-84np9brx	35	3	of	of	IN
cord-002808-84np9brx	35	4	individual	individual	JJ
cord-002808-84np9brx	35	5	cell	cell	NN
cord-002808-84np9brx	35	6	surface	surface	NN
cord-002808-84np9brx	35	7	-	-	HYPH
cord-002808-84np9brx	35	8	bound	bind	VBN
cord-002808-84np9brx	35	9	particles	particle	NNS
cord-002808-84np9brx	35	10	can	can	MD
cord-002808-84np9brx	35	11	be	be	VB
cord-002808-84np9brx	35	12	quite	quite	RB
cord-002808-84np9brx	35	13	rapid	rapid	JJ
cord-002808-84np9brx	35	14	,	,	,
cord-002808-84np9brx	35	15	overall	overall	JJ
cord-002808-84np9brx	35	16	bulk	bulk	JJ
cord-002808-84np9brx	35	17	populationlevel	populationlevel	NN
cord-002808-84np9brx	35	18	internalization	internalization	NN
cord-002808-84np9brx	35	19	is	be	VBZ
cord-002808-84np9brx	35	20	asynchronous	asynchronous	JJ
cord-002808-84np9brx	35	21	and	and	CC
cord-002808-84np9brx	35	22	slow	slow	JJ
cord-002808-84np9brx	35	23	,	,	,
cord-002808-84np9brx	35	24	occurring	occur	VBG
cord-002808-84np9brx	35	25	on	on	IN
cord-002808-84np9brx	35	26	the	the	DT
cord-002808-84np9brx	35	27	time	time	NN
cord-002808-84np9brx	35	28	scale	scale	NN
cord-002808-84np9brx	35	29	of	of	IN
cord-002808-84np9brx	35	30	many	many	JJ
cord-002808-84np9brx	35	31	hours	hour	NNS
cord-002808-84np9brx	35	32	[	[	-LRB-
cord-002808-84np9brx	35	33	24	24	CD
cord-002808-84np9brx	35	34	]	]	-RRB-
cord-002808-84np9brx	35	35	.	.	.
cord-002808-84np9brx	36	1	CD151	cd151	NN
cord-002808-84np9brx	36	2	and	and	CC
cord-002808-84np9brx	36	3	the	the	DT
cord-002808-84np9brx	36	4	associated	associated	JJ
cord-002808-84np9brx	36	5	TEMs	TEMs	NNPS
cord-002808-84np9brx	36	6	likely	likely	RB
cord-002808-84np9brx	36	7	coordinate	coordinate	VB
cord-002808-84np9brx	36	8	organization	organization	NN
cord-002808-84np9brx	36	9	and	and	CC
cord-002808-84np9brx	36	10	assembly	assembly	NN
cord-002808-84np9brx	36	11	of	of	IN
cord-002808-84np9brx	36	12	entry	entry	NN
cord-002808-84np9brx	36	13	receptor	receptor	NN
cord-002808-84np9brx	36	14	complexes	complex	NNS
cord-002808-84np9brx	36	15	;	;	:
cord-002808-84np9brx	36	16	once	once	RB
cord-002808-84np9brx	36	17	assembled	assemble	VBN
cord-002808-84np9brx	36	18	and	and	CC
cord-002808-84np9brx	36	19	bound	bind	VBN
cord-002808-84np9brx	36	20	to	to	IN
cord-002808-84np9brx	36	21	virion	virion	NN
cord-002808-84np9brx	36	22	,	,	,
cord-002808-84np9brx	36	23	these	these	DT
cord-002808-84np9brx	36	24	complexes	complex	NNS
cord-002808-84np9brx	36	25	facilitate	facilitate	VBP
cord-002808-84np9brx	36	26	rapid	rapid	JJ
cord-002808-84np9brx	36	27	entry	entry	NN
cord-002808-84np9brx	36	28	.	.	.
cord-002808-84np9brx	37	1	Similar	similar	JJ
cord-002808-84np9brx	37	2	scaffolding	scaffolding	NN
cord-002808-84np9brx	37	3	roles	role	NNS
cord-002808-84np9brx	37	4	for	for	IN
cord-002808-84np9brx	37	5	other	other	JJ
cord-002808-84np9brx	37	6	tetraspanins	tetraspanin	NNS
cord-002808-84np9brx	37	7	have	have	VBP
cord-002808-84np9brx	37	8	been	be	VBN
cord-002808-84np9brx	37	9	reported	report	VBN
cord-002808-84np9brx	37	10	for	for	IN
cord-002808-84np9brx	37	11	other	other	JJ
cord-002808-84np9brx	37	12	enveloped	envelop	VBN
cord-002808-84np9brx	37	13	and	and	CC
cord-002808-84np9brx	37	14	nonenveloped	nonenvelope	VBN
cord-002808-84np9brx	37	15	viruses	virus	NNS
cord-002808-84np9brx	37	16	[	[	-LRB-
cord-002808-84np9brx	37	17	33	33	CD
cord-002808-84np9brx	37	18	,	,	,
cord-002808-84np9brx	37	19	34	34	CD
cord-002808-84np9brx	37	20	]	]	-RRB-
cord-002808-84np9brx	37	21	.	.	.
cord-002808-84np9brx	38	1	It	-PRON-	PRP
cord-002808-84np9brx	38	2	should	should	MD
cord-002808-84np9brx	38	3	be	be	VB
cord-002808-84np9brx	38	4	noted	note	VBN
cord-002808-84np9brx	38	5	that	that	IN
cord-002808-84np9brx	38	6	many	many	JJ
cord-002808-84np9brx	38	7	of	of	IN
cord-002808-84np9brx	38	8	the	the	DT
cord-002808-84np9brx	38	9	findings	finding	NNS
cord-002808-84np9brx	38	10	summarized	summarize	VBN
cord-002808-84np9brx	38	11	in	in	IN
cord-002808-84np9brx	38	12	this	this	DT
cord-002808-84np9brx	38	13	review	review	NN
cord-002808-84np9brx	38	14	were	be	VBD
cord-002808-84np9brx	38	15	found	find	VBN
cord-002808-84np9brx	38	16	using	use	VBG
cord-002808-84np9brx	38	17	differentiation	differentiation	NN
cord-002808-84np9brx	38	18	-	-	HYPH
cord-002808-84np9brx	38	19	independent	independent	JJ
cord-002808-84np9brx	38	20	pseudovirus	pseudovirus	NN
cord-002808-84np9brx	38	21	(	(	-LRB-
cord-002808-84np9brx	38	22	PsV	PsV	NNP
cord-002808-84np9brx	38	23	)	)	-RRB-
cord-002808-84np9brx	38	24	or	or	CC
cord-002808-84np9brx	38	25	quasivirus	quasivirus	NNP
cord-002808-84np9brx	38	26	(	(	-LRB-
cord-002808-84np9brx	38	27	QsV	QsV	NNP
cord-002808-84np9brx	38	28	)	)	-RRB-
cord-002808-84np9brx	38	29	systems	system	NNS
cord-002808-84np9brx	38	30	for	for	IN
cord-002808-84np9brx	38	31	generating	generate	VBG
cord-002808-84np9brx	38	32	infectious	infectious	JJ
cord-002808-84np9brx	38	33	or	or	CC
cord-002808-84np9brx	38	34	reporter	reporter	NN
cord-002808-84np9brx	38	35	-	-	HYPH
cord-002808-84np9brx	38	36	containing	contain	VBG
cord-002808-84np9brx	38	37	HPV	hpv	NN
cord-002808-84np9brx	38	38	virions	virion	NNS
cord-002808-84np9brx	38	39	in	in	IN
cord-002808-84np9brx	38	40	293TT	293TT	NNP
cord-002808-84np9brx	38	41	cells	cell	NNS
cord-002808-84np9brx	38	42	[	[	-LRB-
cord-002808-84np9brx	38	43	16	16	CD
cord-002808-84np9brx	38	44	]	]	-RRB-
cord-002808-84np9brx	38	45	.	.	.
cord-002808-84np9brx	39	1	While	while	IN
cord-002808-84np9brx	39	2	more	more	JJR
cord-002808-84np9brx	39	3	"	"	``
cord-002808-84np9brx	39	4	native	native	JJ
cord-002808-84np9brx	39	5	"	"	''
cord-002808-84np9brx	39	6	systems	system	NNS
cord-002808-84np9brx	39	7	for	for	IN
cord-002808-84np9brx	39	8	the	the	DT
cord-002808-84np9brx	39	9	generation	generation	NN
cord-002808-84np9brx	39	10	of	of	IN
cord-002808-84np9brx	39	11	HPV	HPV	NNP
cord-002808-84np9brx	39	12	virions	virion	NNS
cord-002808-84np9brx	39	13	like	like	IN
cord-002808-84np9brx	39	14	organotypic	organotypic	JJ
cord-002808-84np9brx	39	15	raft	raft	NN
cord-002808-84np9brx	39	16	systems	system	NNS
cord-002808-84np9brx	39	17	might	may	MD
cord-002808-84np9brx	39	18	be	be	VB
cord-002808-84np9brx	39	19	ideal	ideal	JJ
cord-002808-84np9brx	39	20	,	,	,
cord-002808-84np9brx	39	21	the	the	DT
cord-002808-84np9brx	39	22	293TT	293TT	NNP
cord-002808-84np9brx	39	23	PsV	psv	NN
cord-002808-84np9brx	39	24	/	/	SYM
cord-002808-84np9brx	39	25	QsV	qsv	NN
cord-002808-84np9brx	39	26	system	system	NN
cord-002808-84np9brx	39	27	has	have	VBZ
cord-002808-84np9brx	39	28	been	be	VBN
cord-002808-84np9brx	39	29	invaluable	invaluable	JJ
cord-002808-84np9brx	39	30	for	for	IN
cord-002808-84np9brx	39	31	basic	basic	JJ
cord-002808-84np9brx	39	32	research	research	NN
cord-002808-84np9brx	39	33	on	on	IN
cord-002808-84np9brx	39	34	HPV	HPV	NNP
cord-002808-84np9brx	39	35	,	,	,
cord-002808-84np9brx	39	36	as	as	IN
cord-002808-84np9brx	39	37	the	the	DT
cord-002808-84np9brx	39	38	system	system	NN
cord-002808-84np9brx	39	39	enables	enable	VBZ
cord-002808-84np9brx	39	40	high	high	JJ
cord-002808-84np9brx	39	41	titer	titer	NN
cord-002808-84np9brx	39	42	production	production	NN
cord-002808-84np9brx	39	43	of	of	IN
cord-002808-84np9brx	39	44	highly	highly	RB
cord-002808-84np9brx	39	45	purified	purify	VBN
cord-002808-84np9brx	39	46	infectious	infectious	JJ
cord-002808-84np9brx	39	47	particles	particle	NNS
cord-002808-84np9brx	39	48	,	,	,
cord-002808-84np9brx	39	49	as	as	RB
cord-002808-84np9brx	39	50	well	well	RB
cord-002808-84np9brx	39	51	as	as	IN
cord-002808-84np9brx	39	52	the	the	DT
cord-002808-84np9brx	39	53	means	mean	NNS
cord-002808-84np9brx	39	54	to	to	TO
cord-002808-84np9brx	39	55	generate	generate	VB
cord-002808-84np9brx	39	56	virions	virion	NNS
cord-002808-84np9brx	39	57	that	that	WDT
cord-002808-84np9brx	39	58	package	package	NN
cord-002808-84np9brx	39	59	L2	l2	NN
cord-002808-84np9brx	39	60	fusions	fusion	NNS
cord-002808-84np9brx	39	61	,	,	,
cord-002808-84np9brx	39	62	non	non	JJ
cord-002808-84np9brx	39	63	-	-	JJ
cord-002808-84np9brx	39	64	infectious	infectious	JJ
cord-002808-84np9brx	39	65	L2	L2	NNP
cord-002808-84np9brx	39	66	mutants	mutant	NNS
cord-002808-84np9brx	39	67	,	,	,
cord-002808-84np9brx	39	68	and	and	CC
cord-002808-84np9brx	39	69	5-ethynyl-2	5-ethynyl-2	CD
cord-002808-84np9brx	39	70	-deoxyuridine	-deoxyuridine	JJ
cord-002808-84np9brx	39	71	(	(	-LRB-
cord-002808-84np9brx	39	72	EdU)-labeled	edu)-labele	VBN
cord-002808-84np9brx	39	73	vDNA	vdna	NN
cord-002808-84np9brx	39	74	for	for	IN
cord-002808-84np9brx	39	75	a	a	DT
cord-002808-84np9brx	39	76	variety	variety	NN
cord-002808-84np9brx	39	77	of	of	IN
cord-002808-84np9brx	39	78	experimental	experimental	JJ
cord-002808-84np9brx	39	79	systems	system	NNS
cord-002808-84np9brx	39	80	.	.	.
cord-002808-84np9brx	40	1	For	for	IN
cord-002808-84np9brx	40	2	a	a	DT
cord-002808-84np9brx	40	3	recent	recent	JJ
cord-002808-84np9brx	40	4	review	review	NN
cord-002808-84np9brx	40	5	on	on	IN
cord-002808-84np9brx	40	6	the	the	DT
cord-002808-84np9brx	40	7	differences	difference	NNS
cord-002808-84np9brx	40	8	between	between	IN
cord-002808-84np9brx	40	9	PsV	psv	NN
cord-002808-84np9brx	40	10	/	/	SYM
cord-002808-84np9brx	40	11	QsV	qsv	NN
cord-002808-84np9brx	40	12	and	and	CC
cord-002808-84np9brx	40	13	raft	raft	NN
cord-002808-84np9brx	40	14	-	-	HYPH
cord-002808-84np9brx	40	15	derived	derive	VBN
cord-002808-84np9brx	40	16	HPV	hpv	NN
cord-002808-84np9brx	40	17	,	,	,
cord-002808-84np9brx	40	18	see	see	VB
cord-002808-84np9brx	40	19	[	[	-LRB-
cord-002808-84np9brx	40	20	17	17	CD
cord-002808-84np9brx	40	21	]	]	-RRB-
cord-002808-84np9brx	40	22	.	.	.
cord-002808-84np9brx	41	1	Virion	virion	NN
cord-002808-84np9brx	41	2	binding	bind	VBG
cord-002808-84np9brx	41	3	to	to	IN
cord-002808-84np9brx	41	4	extracellular	extracellular	JJ
cord-002808-84np9brx	41	5	heparin	heparin	NN
cord-002808-84np9brx	41	6	sulfate	sulfate	NN
cord-002808-84np9brx	41	7	proteoglycans	proteoglycan	NNS
cord-002808-84np9brx	41	8	(	(	-LRB-
cord-002808-84np9brx	41	9	HSPGs	hspg	NNS
cord-002808-84np9brx	41	10	)	)	-RRB-
cord-002808-84np9brx	41	11	induces	induce	VBZ
cord-002808-84np9brx	41	12	conformational	conformational	JJ
cord-002808-84np9brx	41	13	changes	change	NNS
cord-002808-84np9brx	41	14	in	in	IN
cord-002808-84np9brx	41	15	both	both	CC
cord-002808-84np9brx	41	16	the	the	DT
cord-002808-84np9brx	41	17	L1	L1	NNP
cord-002808-84np9brx	41	18	and	and	CC
cord-002808-84np9brx	41	19	L2	L2	NNP
cord-002808-84np9brx	41	20	capsid	capsid	NN
cord-002808-84np9brx	41	21	proteins	protein	NNS
cord-002808-84np9brx	41	22	of	of	IN
cord-002808-84np9brx	41	23	the	the	DT
cord-002808-84np9brx	41	24	viral	viral	JJ
cord-002808-84np9brx	41	25	particle	particle	NN
cord-002808-84np9brx	41	26	,	,	,
cord-002808-84np9brx	41	27	and	and	CC
cord-002808-84np9brx	41	28	subsequent	subsequent	JJ
cord-002808-84np9brx	41	29	transfer	transfer	NN
cord-002808-84np9brx	41	30	of	of	IN
cord-002808-84np9brx	41	31	the	the	DT
cord-002808-84np9brx	41	32	virion	virion	NN
cord-002808-84np9brx	41	33	to	to	IN
cord-002808-84np9brx	41	34	a	a	DT
cord-002808-84np9brx	41	35	cell	cell	NN
cord-002808-84np9brx	41	36	surface	surface	NN
cord-002808-84np9brx	41	37	entry	entry	NN
cord-002808-84np9brx	41	38	receptor	receptor	NN
cord-002808-84np9brx	41	39	complex	complex	NN
cord-002808-84np9brx	41	40	[	[	-LRB-
cord-002808-84np9brx	41	41	18	18	CD
cord-002808-84np9brx	41	42	]	]	-RRB-
cord-002808-84np9brx	41	43	[	[	-LRB-
cord-002808-84np9brx	41	44	19	19	CD
cord-002808-84np9brx	41	45	]	]	-RRB-
cord-002808-84np9brx	41	46	[	[	-LRB-
cord-002808-84np9brx	41	47	20	20	CD
cord-002808-84np9brx	41	48	]	]	-RRB-
cord-002808-84np9brx	41	49	.	.	.
cord-002808-84np9brx	42	1	While	while	IN
cord-002808-84np9brx	42	2	bound	bind	VBN
cord-002808-84np9brx	42	3	,	,	,
cord-002808-84np9brx	42	4	cell	cell	NN
cord-002808-84np9brx	42	5	surface	surface	NN
cord-002808-84np9brx	42	6	kallekrein-8	kallekrein-8	NNP
cord-002808-84np9brx	42	7	(	(	-LRB-
cord-002808-84np9brx	42	8	KLK8	KLK8	NNP
cord-002808-84np9brx	42	9	)	)	-RRB-
cord-002808-84np9brx	42	10	and	and	CC
cord-002808-84np9brx	42	11	furin	furin	NN
cord-002808-84np9brx	42	12	cleave	cleave	VB
cord-002808-84np9brx	42	13	the	the	DT
cord-002808-84np9brx	42	14	L1	L1	NNP
cord-002808-84np9brx	42	15	and	and	CC
cord-002808-84np9brx	42	16	L2	L2	NNP
cord-002808-84np9brx	42	17	capsids	capsid	NNS
cord-002808-84np9brx	42	18	,	,	,
cord-002808-84np9brx	42	19	respectively	respectively	RB
cord-002808-84np9brx	42	20	,	,	,
cord-002808-84np9brx	42	21	an	an	DT
cord-002808-84np9brx	42	22	important	important	JJ
cord-002808-84np9brx	42	23	"	"	``
cord-002808-84np9brx	42	24	priming	prime	VBG
cord-002808-84np9brx	42	25	"	"	''
cord-002808-84np9brx	42	26	event	event	NN
cord-002808-84np9brx	42	27	that	that	WDT
cord-002808-84np9brx	42	28	ensures	ensure	VBZ
cord-002808-84np9brx	42	29	the	the	DT
cord-002808-84np9brx	42	30	proper	proper	JJ
cord-002808-84np9brx	42	31	subsequent	subsequent	JJ
cord-002808-84np9brx	42	32	subcellular	subcellular	JJ
cord-002808-84np9brx	42	33	trafficking	trafficking	NN
cord-002808-84np9brx	42	34	of	of	IN
cord-002808-84np9brx	42	35	L2	l2	NN
cord-002808-84np9brx	42	36	/	/	,
cord-002808-84np9brx	42	37	vDNA	vdna	NN
cord-002808-84np9brx	42	38	[	[	-LRB-
cord-002808-84np9brx	42	39	21	21	CD
cord-002808-84np9brx	42	40	]	]	-RRB-
cord-002808-84np9brx	42	41	[	[	-LRB-
cord-002808-84np9brx	42	42	22	22	CD
cord-002808-84np9brx	42	43	]	]	-RRB-
cord-002808-84np9brx	42	44	[	[	-LRB-
cord-002808-84np9brx	42	45	23	23	CD
cord-002808-84np9brx	42	46	]	]	-RRB-
cord-002808-84np9brx	42	47	.	.	.
cord-002808-84np9brx	43	1	Endocytosis	endocytosis	NN
cord-002808-84np9brx	43	2	of	of	IN
cord-002808-84np9brx	43	3	the	the	DT
cord-002808-84np9brx	43	4	virion	virion	NN
cord-002808-84np9brx	43	5	occurs	occur	VBZ
cord-002808-84np9brx	43	6	through	through	IN
cord-002808-84np9brx	43	7	an	an	DT
cord-002808-84np9brx	43	8	actin	actin	NN
cord-002808-84np9brx	43	9	-	-	HYPH
cord-002808-84np9brx	43	10	dependent	dependent	JJ
cord-002808-84np9brx	43	11	process	process	NN
cord-002808-84np9brx	43	12	with	with	IN
cord-002808-84np9brx	43	13	similarities	similarity	NNS
cord-002808-84np9brx	43	14	to	to	IN
cord-002808-84np9brx	43	15	macropinocytosis	macropinocytosis	NNP
cord-002808-84np9brx	43	16	[	[	-LRB-
cord-002808-84np9brx	43	17	24	24	CD
cord-002808-84np9brx	43	18	]	]	-RRB-
cord-002808-84np9brx	43	19	.	.	.
cord-002808-84np9brx	44	1	Tetraspanin	Tetraspanin	NNP
cord-002808-84np9brx	44	2	CD151	CD151	NNP
cord-002808-84np9brx	45	1	and	and	CC
cord-002808-84np9brx	45	2	its	-PRON-	PRP$
cord-002808-84np9brx	45	3	associated	associated	JJ
cord-002808-84np9brx	45	4	α	α	NN
cord-002808-84np9brx	45	5	3	3	CD
cord-002808-84np9brx	45	6	β	β	NN
cord-002808-84np9brx	45	7	1	1	CD
cord-002808-84np9brx	45	8	,	,	,
cord-002808-84np9brx	45	9	α	α	NN
cord-002808-84np9brx	45	10	6	6	CD
cord-002808-84np9brx	45	11	β	β	NN
cord-002808-84np9brx	45	12	1	1	CD
cord-002808-84np9brx	45	13	and	and	CC
cord-002808-84np9brx	45	14	α	α	NN
cord-002808-84np9brx	45	15	6	6	CD
cord-002808-84np9brx	45	16	β	β	NN
cord-002808-84np9brx	45	17	4	4	CD
cord-002808-84np9brx	45	18	integrin	integrin	NN
cord-002808-84np9brx	45	19	partners	partner	NNS
cord-002808-84np9brx	45	20	,	,	,
cord-002808-84np9brx	45	21	growth	growth	NN
cord-002808-84np9brx	45	22	factor	factor	NN
cord-002808-84np9brx	45	23	receptor	receptor	NN
cord-002808-84np9brx	45	24	tyrosine	tyrosine	NN
cord-002808-84np9brx	45	25	kinases	kinase	NNS
cord-002808-84np9brx	45	26	,	,	,
cord-002808-84np9brx	45	27	annexin	annexin	NNP
cord-002808-84np9brx	45	28	A2	A2	NNP
cord-002808-84np9brx	45	29	,	,	,
cord-002808-84np9brx	45	30	and	and	CC
cord-002808-84np9brx	45	31	the	the	DT
cord-002808-84np9brx	45	32	cytoskeletal	cytoskeletal	JJ
cord-002808-84np9brx	45	33	adaptor	adaptor	NN
cord-002808-84np9brx	45	34	obscurin	obscurin	NN
cord-002808-84np9brx	45	35	-	-	HYPH
cord-002808-84np9brx	45	36	like	like	JJ
cord-002808-84np9brx	45	37	1	1	CD
cord-002808-84np9brx	46	1	(	(	-LRB-
cord-002808-84np9brx	46	2	OBSL1	OBSL1	NNP
cord-002808-84np9brx	46	3	)	)	-RRB-
cord-002808-84np9brx	46	4	have	have	VBP
cord-002808-84np9brx	46	5	been	be	VBN
cord-002808-84np9brx	46	6	implicated	implicate	VBN
cord-002808-84np9brx	46	7	in	in	IN
cord-002808-84np9brx	46	8	tetraspanin	tetraspanin	NN
cord-002808-84np9brx	46	9	-	-	HYPH
cord-002808-84np9brx	46	10	enriched	enrich	VBN
cord-002808-84np9brx	46	11	microdomain	microdomain	NN
cord-002808-84np9brx	46	12	(	(	-LRB-
cord-002808-84np9brx	46	13	TEM)-dependent	tem)-dependent	NN
cord-002808-84np9brx	46	14	HPV16	hpv16	NN
cord-002808-84np9brx	46	15	entry	entry	NN
cord-002808-84np9brx	46	16	[	[	-LRB-
cord-002808-84np9brx	46	17	25	25	CD
cord-002808-84np9brx	46	18	]	]	-RRB-
cord-002808-84np9brx	46	19	[	[	-LRB-
cord-002808-84np9brx	46	20	26	26	CD
cord-002808-84np9brx	46	21	]	]	-RRB-
cord-002808-84np9brx	46	22	[	[	-LRB-
cord-002808-84np9brx	46	23	27	27	CD
cord-002808-84np9brx	46	24	]	]	-RRB-
cord-002808-84np9brx	46	25	[	[	-LRB-
cord-002808-84np9brx	46	26	28	28	CD
cord-002808-84np9brx	46	27	]	]	-RRB-
cord-002808-84np9brx	46	28	[	[	-LRB-
cord-002808-84np9brx	46	29	29	29	CD
cord-002808-84np9brx	46	30	]	]	-RRB-
cord-002808-84np9brx	46	31	[	[	-LRB-
cord-002808-84np9brx	46	32	30	30	CD
cord-002808-84np9brx	46	33	]	]	-RRB-
cord-002808-84np9brx	46	34	[	[	-LRB-
cord-002808-84np9brx	46	35	31	31	CD
cord-002808-84np9brx	46	36	]	]	-RRB-
cord-002808-84np9brx	47	1	[	[	-LRB-
cord-002808-84np9brx	47	2	32	32	CD
cord-002808-84np9brx	47	3	]	]	-RRB-
cord-002808-84np9brx	48	1	(	(	-LRB-
cord-002808-84np9brx	48	2	Figure	figure	NN
cord-002808-84np9brx	48	3	2	2	CD
cord-002808-84np9brx	48	4	)	)	-RRB-
cord-002808-84np9brx	48	5	.	.	.
cord-002808-84np9brx	49	1	While	while	IN
cord-002808-84np9brx	49	2	endocytosis	endocytosis	NN
cord-002808-84np9brx	49	3	of	of	IN
cord-002808-84np9brx	49	4	individual	individual	JJ
cord-002808-84np9brx	49	5	cell	cell	NN
cord-002808-84np9brx	49	6	surface	surface	NN
cord-002808-84np9brx	49	7	-	-	HYPH
cord-002808-84np9brx	49	8	bound	bind	VBN
cord-002808-84np9brx	49	9	particles	particle	NNS
cord-002808-84np9brx	49	10	can	can	MD
cord-002808-84np9brx	49	11	be	be	VB
cord-002808-84np9brx	49	12	quite	quite	RB
cord-002808-84np9brx	49	13	rapid	rapid	JJ
cord-002808-84np9brx	49	14	,	,	,
cord-002808-84np9brx	49	15	overall	overall	JJ
cord-002808-84np9brx	49	16	bulk	bulk	JJ
cord-002808-84np9brx	49	17	population	population	NN
cord-002808-84np9brx	49	18	-	-	HYPH
cord-002808-84np9brx	49	19	level	level	NN
cord-002808-84np9brx	49	20	internalization	internalization	NN
cord-002808-84np9brx	49	21	is	be	VBZ
cord-002808-84np9brx	49	22	asynchronous	asynchronous	JJ
cord-002808-84np9brx	49	23	and	and	CC
cord-002808-84np9brx	49	24	slow	slow	JJ
cord-002808-84np9brx	49	25	,	,	,
cord-002808-84np9brx	49	26	occurring	occur	VBG
cord-002808-84np9brx	49	27	on	on	IN
cord-002808-84np9brx	49	28	the	the	DT
cord-002808-84np9brx	49	29	time	time	NN
cord-002808-84np9brx	49	30	scale	scale	NN
cord-002808-84np9brx	49	31	of	of	IN
cord-002808-84np9brx	49	32	many	many	JJ
cord-002808-84np9brx	49	33	hours	hour	NNS
cord-002808-84np9brx	49	34	[	[	-LRB-
cord-002808-84np9brx	49	35	24	24	CD
cord-002808-84np9brx	49	36	]	]	-RRB-
cord-002808-84np9brx	49	37	.	.	.
cord-002808-84np9brx	50	1	CD151	cd151	NN
cord-002808-84np9brx	50	2	and	and	CC
cord-002808-84np9brx	50	3	the	the	DT
cord-002808-84np9brx	50	4	associated	associated	JJ
cord-002808-84np9brx	50	5	TEMs	TEMs	NNPS
cord-002808-84np9brx	50	6	likely	likely	RB
cord-002808-84np9brx	50	7	coordinate	coordinate	VB
cord-002808-84np9brx	50	8	organization	organization	NN
cord-002808-84np9brx	50	9	and	and	CC
cord-002808-84np9brx	50	10	assembly	assembly	NN
cord-002808-84np9brx	50	11	of	of	IN
cord-002808-84np9brx	50	12	entry	entry	NN
cord-002808-84np9brx	50	13	receptor	receptor	NN
cord-002808-84np9brx	50	14	complexes	complex	NNS
cord-002808-84np9brx	50	15	;	;	:
cord-002808-84np9brx	50	16	once	once	RB
cord-002808-84np9brx	50	17	assembled	assemble	VBN
cord-002808-84np9brx	50	18	and	and	CC
cord-002808-84np9brx	50	19	bound	bind	VBN
cord-002808-84np9brx	50	20	to	to	IN
cord-002808-84np9brx	50	21	virion	virion	NN
cord-002808-84np9brx	50	22	,	,	,
cord-002808-84np9brx	50	23	these	these	DT
cord-002808-84np9brx	50	24	complexes	complex	NNS
cord-002808-84np9brx	50	25	facilitate	facilitate	VBP
cord-002808-84np9brx	50	26	rapid	rapid	JJ
cord-002808-84np9brx	50	27	entry	entry	NN
cord-002808-84np9brx	50	28	.	.	.
cord-002808-84np9brx	51	1	Similar	similar	JJ
cord-002808-84np9brx	51	2	scaffolding	scaffolding	NN
cord-002808-84np9brx	51	3	roles	role	NNS
cord-002808-84np9brx	51	4	for	for	IN
cord-002808-84np9brx	51	5	other	other	JJ
cord-002808-84np9brx	51	6	tetraspanins	tetraspanin	NNS
cord-002808-84np9brx	51	7	have	have	VBP
cord-002808-84np9brx	51	8	been	be	VBN
cord-002808-84np9brx	51	9	reported	report	VBN
cord-002808-84np9brx	51	10	for	for	IN
cord-002808-84np9brx	51	11	other	other	JJ
cord-002808-84np9brx	51	12	enveloped	envelop	VBN
cord-002808-84np9brx	51	13	and	and	CC
cord-002808-84np9brx	51	14	nonenveloped	nonenvelope	VBN
cord-002808-84np9brx	51	15	viruses	virus	NNS
cord-002808-84np9brx	51	16	[	[	-LRB-
cord-002808-84np9brx	51	17	33	33	CD
cord-002808-84np9brx	51	18	,	,	,
cord-002808-84np9brx	51	19	34	34	CD
cord-002808-84np9brx	51	20	]	]	-RRB-
cord-002808-84np9brx	51	21	.	.	.
cord-002808-84np9brx	52	1	Early	early	JJ
cord-002808-84np9brx	52	2	subcellular	subcellular	JJ
cord-002808-84np9brx	52	3	trafficking	trafficking	NN
cord-002808-84np9brx	52	4	and	and	CC
cord-002808-84np9brx	52	5	uncoating	uncoating	NN
cord-002808-84np9brx	52	6	.	.	.
cord-002808-84np9brx	53	1	Internalized	internalize	VBN
cord-002808-84np9brx	53	2	virions	virion	NNS
cord-002808-84np9brx	53	3	,	,	,
cord-002808-84np9brx	53	4	primed	prime	VBN
cord-002808-84np9brx	53	5	by	by	IN
cord-002808-84np9brx	53	6	cleavage	cleavage	NN
cord-002808-84np9brx	53	7	on	on	IN
cord-002808-84np9brx	53	8	the	the	DT
cord-002808-84np9brx	53	9	cell	cell	NN
cord-002808-84np9brx	53	10	surface	surface	NN
cord-002808-84np9brx	53	11	,	,	,
cord-002808-84np9brx	53	12	enter	enter	VB
cord-002808-84np9brx	53	13	the	the	DT
cord-002808-84np9brx	53	14	endolysosomal	endolysosomal	JJ
cord-002808-84np9brx	53	15	pathway	pathway	NN
cord-002808-84np9brx	53	16	and	and	CC
cord-002808-84np9brx	53	17	begin	begin	VB
cord-002808-84np9brx	53	18	pH	ph	NN
cord-002808-84np9brx	53	19	-	-	HYPH
cord-002808-84np9brx	53	20	dependent	dependent	JJ
cord-002808-84np9brx	53	21	uncoating	uncoating	NN
cord-002808-84np9brx	53	22	and	and	CC
cord-002808-84np9brx	53	23	L2	L2	NNP
cord-002808-84np9brx	53	24	insertion	insertion	NN
cord-002808-84np9brx	53	25	/	/	SYM
cord-002808-84np9brx	53	26	penetration	penetration	NN
cord-002808-84np9brx	53	27	.	.	.
cord-002808-84np9brx	54	1	L2	L2	NNP
cord-002808-84np9brx	54	2	recruitment	recruitment	NN
cord-002808-84np9brx	54	3	of	of	IN
cord-002808-84np9brx	54	4	cytosolic	cytosolic	JJ
cord-002808-84np9brx	54	5	sorting	sorting	NN
cord-002808-84np9brx	54	6	factors	factor	NNS
cord-002808-84np9brx	54	7	including	include	VBG
cord-002808-84np9brx	54	8	sorting	sort	VBG
cord-002808-84np9brx	54	9	nexins	nexin	NNS
cord-002808-84np9brx	54	10	(	(	-LRB-
cord-002808-84np9brx	54	11	SNXs	SNXs	NNP
cord-002808-84np9brx	54	12	)	)	-RRB-
cord-002808-84np9brx	54	13	and	and	CC
cord-002808-84np9brx	54	14	retromer	retromer	NNP
cord-002808-84np9brx	54	15	modulates	modulate	VBZ
cord-002808-84np9brx	54	16	the	the	DT
cord-002808-84np9brx	54	17	trafficking	traffic	VBG
cord-002808-84np9brx	54	18	pathway	pathway	NN
cord-002808-84np9brx	54	19	.	.	.
cord-002808-84np9brx	55	1	Retromer	retromer	NN
cord-002808-84np9brx	55	2	binding	binding	NN
cord-002808-84np9brx	55	3	is	be	VBZ
cord-002808-84np9brx	55	4	important	important	JJ
cord-002808-84np9brx	55	5	for	for	IN
cord-002808-84np9brx	55	6	EE	EE	NNP
cord-002808-84np9brx	55	7	to	to	IN
cord-002808-84np9brx	55	8	LE	LE	NNP
cord-002808-84np9brx	55	9	/	/	SYM
cord-002808-84np9brx	55	10	MVB	MVB	NNP
cord-002808-84np9brx	55	11	transport	transport	NN
cord-002808-84np9brx	55	12	.	.	.
cord-002808-84np9brx	56	1	Retrograde	retrograde	JJ
cord-002808-84np9brx	56	2	transport	transport	NN
cord-002808-84np9brx	56	3	of	of	IN
cord-002808-84np9brx	56	4	L2	l2	NN
cord-002808-84np9brx	56	5	/	/	,
cord-002808-84np9brx	56	6	vDNA	vdna	NN
cord-002808-84np9brx	56	7	from	from	IN
cord-002808-84np9brx	56	8	LE	LE	NNP
cord-002808-84np9brx	56	9	/	/	SYM
cord-002808-84np9brx	56	10	MVBs	MVBs	NNP
cord-002808-84np9brx	56	11	to	to	IN
cord-002808-84np9brx	56	12	the	the	DT
cord-002808-84np9brx	56	13	trans	trans	NNP
cord-002808-84np9brx	56	14	-	-	NNP
cord-002808-84np9brx	56	15	Golgi	Golgi	NNP
cord-002808-84np9brx	56	16	network	network	NN
cord-002808-84np9brx	56	17	(	(	-LRB-
cord-002808-84np9brx	56	18	TGN	TGN	NNP
cord-002808-84np9brx	56	19	)	)	-RRB-
cord-002808-84np9brx	56	20	occurs	occur	VBZ
cord-002808-84np9brx	56	21	in	in	IN
cord-002808-84np9brx	56	22	a	a	DT
cord-002808-84np9brx	56	23	furin-	furin-	JJ
cord-002808-84np9brx	56	24	,	,	,
cord-002808-84np9brx	56	25	cyclophilin	cyclophilin	NNP
cord-002808-84np9brx	56	26	-	-	HYPH
cord-002808-84np9brx	56	27	γ	γ	NNP
cord-002808-84np9brx	56	28	-	-	HYPH
cord-002808-84np9brx	56	29	sec-	sec-	NN
cord-002808-84np9brx	56	30	,	,	,
cord-002808-84np9brx	56	31	and	and	CC
cord-002808-84np9brx	56	32	pH	ph	NN
cord-002808-84np9brx	56	33	-	-	HYPH
cord-002808-84np9brx	56	34	dependent	dependent	JJ
cord-002808-84np9brx	56	35	manner	manner	NN
cord-002808-84np9brx	56	36	.	.	.
cord-002808-84np9brx	57	1	Cleavage	cleavage	NN
cord-002808-84np9brx	57	2	of	of	IN
cord-002808-84np9brx	57	3	L2	l2	NN
cord-002808-84np9brx	57	4	by	by	IN
cord-002808-84np9brx	57	5	the	the	DT
cord-002808-84np9brx	57	6	host	host	NN
cord-002808-84np9brx	57	7	protease	protease	NN
cord-002808-84np9brx	57	8	furin	furin	NN
cord-002808-84np9brx	57	9	occurs	occur	VBZ
cord-002808-84np9brx	57	10	on	on	IN
cord-002808-84np9brx	57	11	the	the	DT
cord-002808-84np9brx	57	12	surface	surface	NN
cord-002808-84np9brx	57	13	of	of	IN
cord-002808-84np9brx	57	14	host	host	NN
cord-002808-84np9brx	57	15	cells	cell	NNS
cord-002808-84np9brx	57	16	and	and	CC
cord-002808-84np9brx	57	17	on	on	IN
cord-002808-84np9brx	57	18	the	the	DT
cord-002808-84np9brx	57	19	extracellular	extracellular	JJ
cord-002808-84np9brx	57	20	matrix	matrix	NN
cord-002808-84np9brx	57	21	(	(	-LRB-
cord-002808-84np9brx	57	22	ECM	ECM	NNP
cord-002808-84np9brx	57	23	)	)	-RRB-
cord-002808-84np9brx	57	24	in	in	IN
cord-002808-84np9brx	57	25	response	response	NN
cord-002808-84np9brx	57	26	to	to	IN
cord-002808-84np9brx	57	27	binding	bind	VBG
cord-002808-84np9brx	57	28	of	of	IN
cord-002808-84np9brx	57	29	the	the	DT
cord-002808-84np9brx	57	30	virion	virion	NN
cord-002808-84np9brx	57	31	to	to	IN
cord-002808-84np9brx	57	32	HSPGs	hspg	NNS
cord-002808-84np9brx	57	33	[	[	-LRB-
cord-002808-84np9brx	57	34	35	35	CD
cord-002808-84np9brx	57	35	]	]	-RRB-
cord-002808-84np9brx	57	36	.	.	.
cord-002808-84np9brx	58	1	This	this	DT
cord-002808-84np9brx	58	2	cleavage	cleavage	NN
cord-002808-84np9brx	58	3	occurs	occur	VBZ
cord-002808-84np9brx	58	4	C	c	NN
cord-002808-84np9brx	58	5	-	-	HYPH
cord-002808-84np9brx	58	6	terminal	terminal	NN
cord-002808-84np9brx	58	7	to	to	IN
cord-002808-84np9brx	58	8	the	the	DT
cord-002808-84np9brx	58	9	final	final	JJ
cord-002808-84np9brx	58	10	arginine	arginine	NN
cord-002808-84np9brx	58	11	residue	residue	NN
cord-002808-84np9brx	58	12	of	of	IN
cord-002808-84np9brx	58	13	a	a	DT
cord-002808-84np9brx	58	14	conserved	conserved	JJ
cord-002808-84np9brx	58	15	consensus	consensus	NN
cord-002808-84np9brx	58	16	site	site	NN
cord-002808-84np9brx	58	17	(	(	-LRB-
cord-002808-84np9brx	58	18	RTKR	RTKR	NNP
cord-002808-84np9brx	58	19	,	,	,
cord-002808-84np9brx	58	20	residues	residue	NNS
cord-002808-84np9brx	58	21	9	9	CD
cord-002808-84np9brx	58	22	-	-	SYM
cord-002808-84np9brx	58	23	12	12	CD
cord-002808-84np9brx	58	24	for	for	IN
cord-002808-84np9brx	58	25	HPV16	hpv16	ADD
cord-002808-84np9brx	58	26	)	)	-RRB-
cord-002808-84np9brx	58	27	,	,	,
cord-002808-84np9brx	58	28	removing	remove	VBG
cord-002808-84np9brx	58	29	twelve	twelve	CD
cord-002808-84np9brx	58	30	N	n	CD
cord-002808-84np9brx	58	31	-	-	HYPH
cord-002808-84np9brx	58	32	terminal	terminal	NN
cord-002808-84np9brx	58	33	residues	residue	NNS
cord-002808-84np9brx	58	34	of	of	IN
cord-002808-84np9brx	58	35	HPV16	hpv16	NN
cord-002808-84np9brx	58	36	L2	L2	NNP
cord-002808-84np9brx	58	37	[	[	-LRB-
cord-002808-84np9brx	58	38	36	36	CD
cord-002808-84np9brx	58	39	]	]	-RRB-
cord-002808-84np9brx	59	1	(	(	-LRB-
cord-002808-84np9brx	59	2	Figure	figure	NN
cord-002808-84np9brx	59	3	1	1	CD
cord-002808-84np9brx	59	4	)	)	-RRB-
cord-002808-84np9brx	59	5	.	.	.
cord-002808-84np9brx	60	1	The	the	DT
cord-002808-84np9brx	60	2	molecular	molecular	JJ
cord-002808-84np9brx	60	3	basis	basis	NN
cord-002808-84np9brx	60	4	for	for	IN
cord-002808-84np9brx	60	5	the	the	DT
cord-002808-84np9brx	60	6	requirement	requirement	NN
cord-002808-84np9brx	60	7	of	of	IN
cord-002808-84np9brx	60	8	this	this	DT
cord-002808-84np9brx	60	9	cleavage	cleavage	NN
cord-002808-84np9brx	60	10	remains	remain	VBZ
cord-002808-84np9brx	60	11	unknown	unknown	JJ
cord-002808-84np9brx	60	12	,	,	,
cord-002808-84np9brx	60	13	but	but	CC
cord-002808-84np9brx	60	14	inhibition	inhibition	NN
cord-002808-84np9brx	60	15	of	of	IN
cord-002808-84np9brx	60	16	cleavage	cleavage	NN
cord-002808-84np9brx	60	17	through	through	IN
cord-002808-84np9brx	60	18	mutation	mutation	NN
cord-002808-84np9brx	60	19	of	of	IN
cord-002808-84np9brx	60	20	the	the	DT
cord-002808-84np9brx	60	21	cleavage	cleavage	NN
cord-002808-84np9brx	60	22	site	site	NN
cord-002808-84np9brx	60	23	or	or	CC
cord-002808-84np9brx	60	24	by	by	IN
cord-002808-84np9brx	60	25	biochemical	biochemical	JJ
cord-002808-84np9brx	60	26	inhibition	inhibition	NN
cord-002808-84np9brx	60	27	of	of	IN
cord-002808-84np9brx	60	28	furin	furin	NN
cord-002808-84np9brx	60	29	results	result	NNS
cord-002808-84np9brx	60	30	in	in	IN
cord-002808-84np9brx	60	31	aberrant	aberrant	JJ
cord-002808-84np9brx	60	32	trafficking	trafficking	NN
cord-002808-84np9brx	60	33	of	of	IN
cord-002808-84np9brx	60	34	the	the	DT
cord-002808-84np9brx	60	35	L2	L2	NNP
cord-002808-84np9brx	60	36	/	/	SYM
cord-002808-84np9brx	60	37	vDNA	vdna	RB
cord-002808-84np9brx	60	38	complex	complex	JJ
cord-002808-84np9brx	60	39	and	and	CC
cord-002808-84np9brx	60	40	potent	potent	JJ
cord-002808-84np9brx	60	41	abrogation	abrogation	NN
cord-002808-84np9brx	60	42	of	of	IN
cord-002808-84np9brx	60	43	infection	infection	NN
cord-002808-84np9brx	60	44	[	[	-LRB-
cord-002808-84np9brx	60	45	23	23	CD
cord-002808-84np9brx	60	46	]	]	-RRB-
cord-002808-84np9brx	60	47	.	.	.
cord-002808-84np9brx	61	1	Cleavage	cleavage	NN
cord-002808-84np9brx	61	2	appears	appear	VBZ
cord-002808-84np9brx	61	3	to	to	TO
cord-002808-84np9brx	61	4	trigger	trigger	VB
cord-002808-84np9brx	61	5	a	a	DT
cord-002808-84np9brx	61	6	conformational	conformational	JJ
cord-002808-84np9brx	61	7	change	change	NN
cord-002808-84np9brx	61	8	in	in	IN
cord-002808-84np9brx	61	9	capsid	capsid	NN
cord-002808-84np9brx	61	10	and/or	and/or	CC
cord-002808-84np9brx	61	11	L2	L2	NNP
cord-002808-84np9brx	61	12	structure	structure	NN
cord-002808-84np9brx	61	13	,	,	,
cord-002808-84np9brx	61	14	as	as	IN
cord-002808-84np9brx	61	15	the	the	DT
cord-002808-84np9brx	61	16	conserved	conserved	JJ
cord-002808-84np9brx	61	17	and	and	CC
cord-002808-84np9brx	61	18	neutralizing	neutralize	VBG
cord-002808-84np9brx	61	19	RG-1	RG-1	NNP
cord-002808-84np9brx	61	20	epitope	epitope	NN
cord-002808-84np9brx	61	21	(	(	-LRB-
cord-002808-84np9brx	61	22	residues	residue	NNS
cord-002808-84np9brx	61	23	17	17	CD
cord-002808-84np9brx	61	24	-	-	SYM
cord-002808-84np9brx	61	25	36	36	CD
cord-002808-84np9brx	61	26	for	for	IN
cord-002808-84np9brx	61	27	HPV16	hpv16	ADD
cord-002808-84np9brx	61	28	[	[	-LRB-
cord-002808-84np9brx	61	29	37	37	CD
cord-002808-84np9brx	61	30	]	]	-RRB-
cord-002808-84np9brx	61	31	)	)	-RRB-
cord-002808-84np9brx	61	32	becomes	become	VBZ
cord-002808-84np9brx	61	33	accessible	accessible	JJ
cord-002808-84np9brx	61	34	to	to	IN
cord-002808-84np9brx	61	35	antibody	antibody	NN
cord-002808-84np9brx	61	36	staining	stain	VBG
cord-002808-84np9brx	61	37	shortly	shortly	RB
cord-002808-84np9brx	61	38	after	after	IN
cord-002808-84np9brx	61	39	virion	virion	NN
cord-002808-84np9brx	61	40	binding	bind	VBG
cord-002808-84np9brx	61	41	in	in	IN
cord-002808-84np9brx	61	42	a	a	DT
cord-002808-84np9brx	61	43	furin	furin	NN
cord-002808-84np9brx	61	44	-	-	HYPH
cord-002808-84np9brx	61	45	dependent	dependent	JJ
cord-002808-84np9brx	61	46	manner	manner	NN
cord-002808-84np9brx	61	47	[	[	-LRB-
cord-002808-84np9brx	61	48	38	38	CD
cord-002808-84np9brx	61	49	]	]	-RRB-
cord-002808-84np9brx	61	50	.	.	.
cord-002808-84np9brx	62	1	Cell	cell	NN
cord-002808-84np9brx	62	2	surface	surface	NN
cord-002808-84np9brx	62	3	cyclophilins	cyclophilin	NNS
cord-002808-84np9brx	62	4	(	(	-LRB-
cord-002808-84np9brx	62	5	peptidyl	peptidyl	NNP
cord-002808-84np9brx	62	6	-	-	HYPH
cord-002808-84np9brx	62	7	prolyl	prolyl	JJ
cord-002808-84np9brx	62	8	isomerases	isomerase	NNS
cord-002808-84np9brx	62	9	,	,	,
cord-002808-84np9brx	62	10	PPIs	ppi	NNS
cord-002808-84np9brx	62	11	)	)	-RRB-
cord-002808-84np9brx	62	12	also	also	RB
cord-002808-84np9brx	62	13	appear	appear	VBP
cord-002808-84np9brx	62	14	to	to	TO
cord-002808-84np9brx	62	15	modulate	modulate	VB
cord-002808-84np9brx	62	16	the	the	DT
cord-002808-84np9brx	62	17	conformation	conformation	NN
cord-002808-84np9brx	62	18	of	of	IN
cord-002808-84np9brx	62	19	L2	L2	NNP
cord-002808-84np9brx	62	20	,	,	,
cord-002808-84np9brx	62	21	as	as	IN
cord-002808-84np9brx	62	22	RG-1	RG-1	NNP
cord-002808-84np9brx	62	23	epitope	epitope	NN
cord-002808-84np9brx	62	24	exposure	exposure	NN
cord-002808-84np9brx	62	25	is	be	VBZ
cord-002808-84np9brx	62	26	sensitive	sensitive	JJ
cord-002808-84np9brx	62	27	to	to	IN
cord-002808-84np9brx	62	28	cyclosporine	cyclosporine	NNP
cord-002808-84np9brx	62	29	A	A	NNP
cord-002808-84np9brx	62	30	,	,	,
cord-002808-84np9brx	62	31	a	a	DT
cord-002808-84np9brx	62	32	broad	broad	JJ
cord-002808-84np9brx	62	33	PPI	PPI	NNP
cord-002808-84np9brx	62	34	inhibitor	inhibitor	NN
cord-002808-84np9brx	62	35	[	[	-LRB-
cord-002808-84np9brx	62	36	39	39	CD
cord-002808-84np9brx	62	37	]	]	-RRB-
cord-002808-84np9brx	62	38	.	.	.
cord-002808-84np9brx	63	1	RG-1	RG-1	NNP
cord-002808-84np9brx	64	1	epitope	epitope	NN
cord-002808-84np9brx	64	2	exposure	exposure	NN
cord-002808-84np9brx	64	3	was	be	VBD
cord-002808-84np9brx	64	4	initially	initially	RB
cord-002808-84np9brx	64	5	believed	believe	VBN
cord-002808-84np9brx	64	6	to	to	TO
cord-002808-84np9brx	64	7	be	be	VB
cord-002808-84np9brx	64	8	a	a	DT
cord-002808-84np9brx	64	9	convenient	convenient	JJ
cord-002808-84np9brx	64	10	marker	marker	NN
cord-002808-84np9brx	64	11	for	for	IN
cord-002808-84np9brx	64	12	furin	furin	NN
cord-002808-84np9brx	64	13	cleavage	cleavage	NN
cord-002808-84np9brx	64	14	,	,	,
cord-002808-84np9brx	64	15	and	and	CC
cord-002808-84np9brx	64	16	cyclophilins	cyclophilins	NNP
cord-002808-84np9brx	64	17	were	be	VBD
cord-002808-84np9brx	64	18	believed	believe	VBN
cord-002808-84np9brx	64	19	to	to	TO
cord-002808-84np9brx	64	20	control	control	VB
cord-002808-84np9brx	64	21	L2	L2	NNP
cord-002808-84np9brx	64	22	accessibility	accessibility	NN
cord-002808-84np9brx	64	23	and	and	CC
cord-002808-84np9brx	64	24	susceptibility	susceptibility	NN
cord-002808-84np9brx	64	25	to	to	IN
cord-002808-84np9brx	64	26	furin	furin	NN
cord-002808-84np9brx	64	27	,	,	,
cord-002808-84np9brx	64	28	but	but	CC
cord-002808-84np9brx	64	29	recent	recent	JJ
cord-002808-84np9brx	64	30	work	work	NN
cord-002808-84np9brx	64	31	disfavors	disfavor	VBZ
cord-002808-84np9brx	64	32	this	this	DT
cord-002808-84np9brx	64	33	idea	idea	NN
cord-002808-84np9brx	64	34	,	,	,
cord-002808-84np9brx	64	35	as	as	IN
cord-002808-84np9brx	64	36	furin	furin	NN
cord-002808-84np9brx	64	37	cleavage	cleavage	NN
cord-002808-84np9brx	64	38	still	still	RB
cord-002808-84np9brx	64	39	occurs	occur	VBZ
cord-002808-84np9brx	64	40	despite	despite	IN
cord-002808-84np9brx	64	41	PPI	PPI	NNP
cord-002808-84np9brx	64	42	inhibition	inhibition	NN
cord-002808-84np9brx	64	43	of	of	IN
cord-002808-84np9brx	64	44	RG-1	RG-1	NNP
cord-002808-84np9brx	64	45	exposure	exposure	NN
cord-002808-84np9brx	64	46	[	[	-LRB-
cord-002808-84np9brx	64	47	36	36	CD
cord-002808-84np9brx	64	48	]	]	-RRB-
cord-002808-84np9brx	64	49	.	.	.
cord-002808-84np9brx	65	1	Thus	thus	RB
cord-002808-84np9brx	65	2	,	,	,
cord-002808-84np9brx	65	3	while	while	IN
cord-002808-84np9brx	65	4	RG-1	RG-1	NNP
cord-002808-84np9brx	65	5	staining	staining	NN
cord-002808-84np9brx	65	6	is	be	VBZ
cord-002808-84np9brx	65	7	a	a	DT
cord-002808-84np9brx	65	8	convenient	convenient	JJ
cord-002808-84np9brx	65	9	marker	marker	NN
cord-002808-84np9brx	65	10	for	for	IN
cord-002808-84np9brx	65	11	an	an	DT
cord-002808-84np9brx	65	12	L2	L2	NNP
cord-002808-84np9brx	65	13	conformational	conformational	JJ
cord-002808-84np9brx	65	14	change	change	NN
cord-002808-84np9brx	65	15	that	that	WDT
cord-002808-84np9brx	65	16	is	be	VBZ
cord-002808-84np9brx	65	17	both	both	DT
cord-002808-84np9brx	65	18	furin	furin	NN
cord-002808-84np9brx	65	19	-	-	HYPH
cord-002808-84np9brx	65	20	and	and	CC
cord-002808-84np9brx	65	21	cyclophilin	cyclophilin	NN
cord-002808-84np9brx	65	22	-	-	HYPH
cord-002808-84np9brx	65	23	dependent	dependent	JJ
cord-002808-84np9brx	65	24	,	,	,
cord-002808-84np9brx	65	25	it	-PRON-	PRP
cord-002808-84np9brx	65	26	is	be	VBZ
cord-002808-84np9brx	65	27	not	not	RB
cord-002808-84np9brx	65	28	a	a	DT
cord-002808-84np9brx	65	29	direct	direct	JJ
cord-002808-84np9brx	65	30	readout	readout	NN
cord-002808-84np9brx	65	31	for	for	IN
cord-002808-84np9brx	65	32	furin	furin	NN
cord-002808-84np9brx	65	33	proteolysis	proteolysis	NN
cord-002808-84np9brx	65	34	of	of	IN
cord-002808-84np9brx	65	35	L2	L2	NNP
cord-002808-84np9brx	65	36	,	,	,
cord-002808-84np9brx	65	37	as	as	IN
cord-002808-84np9brx	65	38	cleavage	cleavage	NN
cord-002808-84np9brx	65	39	can	can	MD
cord-002808-84np9brx	65	40	occur	occur	VB
cord-002808-84np9brx	65	41	without	without	IN
cord-002808-84np9brx	65	42	RG-1	RG-1	NNP
cord-002808-84np9brx	65	43	exposure	exposure	NN
cord-002808-84np9brx	65	44	.	.	.
cord-002808-84np9brx	66	1	Shortly	shortly	RB
cord-002808-84np9brx	66	2	after	after	IN
cord-002808-84np9brx	66	3	entry	entry	NN
cord-002808-84np9brx	66	4	,	,	,
cord-002808-84np9brx	66	5	early	early	JJ
cord-002808-84np9brx	66	6	trafficking	trafficking	NN
cord-002808-84np9brx	66	7	of	of	IN
cord-002808-84np9brx	66	8	HPV	HPV	NNP
cord-002808-84np9brx	66	9	is	be	VBZ
cord-002808-84np9brx	66	10	modulated	modulate	VBN
cord-002808-84np9brx	66	11	by	by	IN
cord-002808-84np9brx	66	12	the	the	DT
cord-002808-84np9brx	66	13	tetraspanin	tetraspanin	NNP
cord-002808-84np9brx	66	14	CD63	CD63	NNP
cord-002808-84np9brx	66	15	and	and	CC
cord-002808-84np9brx	66	16	its	-PRON-	PRP$
cord-002808-84np9brx	66	17	partners	partner	NNS
cord-002808-84np9brx	67	1	syntenin	syntenin	NNP
cord-002808-84np9brx	67	2	/	/	SYM
cord-002808-84np9brx	67	3	ALIX	ALIX	NNP
cord-002808-84np9brx	67	4	[	[	-LRB-
cord-002808-84np9brx	67	5	40	40	CD
cord-002808-84np9brx	67	6	]	]	-RRB-
cord-002808-84np9brx	67	7	.	.	.
cord-002808-84np9brx	68	1	These	these	DT
cord-002808-84np9brx	68	2	molecules	molecule	NNS
cord-002808-84np9brx	68	3	are	be	VBP
cord-002808-84np9brx	68	4	necessary	necessary	JJ
cord-002808-84np9brx	68	5	for	for	IN
cord-002808-84np9brx	68	6	sorting	sort	VBG
cord-002808-84np9brx	68	7	of	of	IN
cord-002808-84np9brx	68	8	HPV	hpv	NN
cord-002808-84np9brx	68	9	virions	virion	NNS
cord-002808-84np9brx	68	10	from	from	IN
cord-002808-84np9brx	68	11	early	early	JJ
cord-002808-84np9brx	68	12	endosomes	endosome	NNS
cord-002808-84np9brx	68	13	(	(	-LRB-
cord-002808-84np9brx	68	14	EE	EE	NNP
cord-002808-84np9brx	68	15	)	)	-RRB-
cord-002808-84np9brx	68	16	into	into	IN
cord-002808-84np9brx	68	17	acidic	acidic	JJ
cord-002808-84np9brx	68	18	late	late	JJ
cord-002808-84np9brx	68	19	endosome	endosome	NN
cord-002808-84np9brx	68	20	(	(	-LRB-
cord-002808-84np9brx	68	21	LE	LE	NNP
cord-002808-84np9brx	68	22	)	)	-RRB-
cord-002808-84np9brx	68	23	and	and	CC
cord-002808-84np9brx	68	24	multivesicular	multivesicular	NNP
cord-002808-84np9brx	68	25	bodies	body	NNS
cord-002808-84np9brx	68	26	(	(	-LRB-
cord-002808-84np9brx	68	27	MVBs	MVBs	NNP
cord-002808-84np9brx	68	28	)	)	-RRB-
cord-002808-84np9brx	68	29	,	,	,
cord-002808-84np9brx	68	30	a	a	DT
cord-002808-84np9brx	68	31	prerequisite	prerequisite	NN
cord-002808-84np9brx	68	32	for	for	IN
cord-002808-84np9brx	68	33	capsid	capsid	NN
cord-002808-84np9brx	68	34	disassembly	disassembly	NN
cord-002808-84np9brx	68	35	,	,	,
cord-002808-84np9brx	68	36	uncoating	uncoating	NN
cord-002808-84np9brx	68	37	,	,	,
cord-002808-84np9brx	68	38	and	and	CC
cord-002808-84np9brx	68	39	segregation	segregation	NN
cord-002808-84np9brx	68	40	of	of	IN
cord-002808-84np9brx	68	41	L2	l2	NN
cord-002808-84np9brx	68	42	/	/	,
cord-002808-84np9brx	68	43	vDNA	vdna	NN
cord-002808-84np9brx	68	44	from	from	IN
cord-002808-84np9brx	68	45	L1	L1	NNP
cord-002808-84np9brx	68	46	(	(	-LRB-
cord-002808-84np9brx	68	47	Figure	figure	NN
cord-002808-84np9brx	68	48	2	2	CD
cord-002808-84np9brx	68	49	)	)	-RRB-
cord-002808-84np9brx	68	50	.	.	.
cord-002808-84np9brx	69	1	When	when	WRB
cord-002808-84np9brx	69	2	MVB	MVB	NNP
cord-002808-84np9brx	69	3	trafficking	trafficking	NN
cord-002808-84np9brx	69	4	of	of	IN
cord-002808-84np9brx	69	5	HPV	HPV	NNP
cord-002808-84np9brx	69	6	was	be	VBD
cord-002808-84np9brx	69	7	interrupted	interrupt	VBN
cord-002808-84np9brx	69	8	by	by	IN
cord-002808-84np9brx	69	9	knockdown	knockdown	NN
cord-002808-84np9brx	69	10	of	of	IN
cord-002808-84np9brx	69	11	either	either	DT
cord-002808-84np9brx	69	12	CD63	CD63	NNP
cord-002808-84np9brx	69	13	or	or	CC
cord-002808-84np9brx	69	14	syntenin	syntenin	NNP
cord-002808-84np9brx	69	15	,	,	,
cord-002808-84np9brx	69	16	subcellular	subcellular	JJ
cord-002808-84np9brx	69	17	transport	transport	NN
cord-002808-84np9brx	69	18	Cleavage	cleavage	NN
cord-002808-84np9brx	69	19	of	of	IN
cord-002808-84np9brx	69	20	L2	L2	NNP
cord-002808-84np9brx	69	21	by	by	IN
cord-002808-84np9brx	69	22	the	the	DT
cord-002808-84np9brx	69	23	host	host	NN
cord-002808-84np9brx	69	24	protease	protease	NN
cord-002808-84np9brx	69	25	furin	furin	NN
cord-002808-84np9brx	69	26	occurs	occur	VBZ
cord-002808-84np9brx	69	27	on	on	IN
cord-002808-84np9brx	69	28	the	the	DT
cord-002808-84np9brx	69	29	surface	surface	NN
cord-002808-84np9brx	69	30	of	of	IN
cord-002808-84np9brx	69	31	host	host	NN
cord-002808-84np9brx	69	32	cells	cell	NNS
cord-002808-84np9brx	69	33	and	and	CC
cord-002808-84np9brx	69	34	on	on	IN
cord-002808-84np9brx	69	35	the	the	DT
cord-002808-84np9brx	69	36	extracellular	extracellular	JJ
cord-002808-84np9brx	69	37	matrix	matrix	NN
cord-002808-84np9brx	69	38	(	(	-LRB-
cord-002808-84np9brx	69	39	ECM	ECM	NNP
cord-002808-84np9brx	69	40	)	)	-RRB-
cord-002808-84np9brx	69	41	in	in	IN
cord-002808-84np9brx	69	42	response	response	NN
cord-002808-84np9brx	69	43	to	to	IN
cord-002808-84np9brx	69	44	binding	bind	VBG
cord-002808-84np9brx	69	45	of	of	IN
cord-002808-84np9brx	69	46	the	the	DT
cord-002808-84np9brx	69	47	virion	virion	NN
cord-002808-84np9brx	69	48	to	to	IN
cord-002808-84np9brx	69	49	HSPGs	hspg	NNS
cord-002808-84np9brx	69	50	[	[	-LRB-
cord-002808-84np9brx	69	51	35	35	CD
cord-002808-84np9brx	69	52	]	]	-RRB-
cord-002808-84np9brx	69	53	.	.	.
cord-002808-84np9brx	70	1	This	this	DT
cord-002808-84np9brx	70	2	cleavage	cleavage	NN
cord-002808-84np9brx	70	3	occurs	occur	VBZ
cord-002808-84np9brx	70	4	C	c	NN
cord-002808-84np9brx	70	5	-	-	HYPH
cord-002808-84np9brx	70	6	terminal	terminal	NN
cord-002808-84np9brx	70	7	to	to	IN
cord-002808-84np9brx	70	8	the	the	DT
cord-002808-84np9brx	70	9	final	final	JJ
cord-002808-84np9brx	70	10	arginine	arginine	NN
cord-002808-84np9brx	70	11	residue	residue	NN
cord-002808-84np9brx	70	12	of	of	IN
cord-002808-84np9brx	70	13	a	a	DT
cord-002808-84np9brx	70	14	conserved	conserved	JJ
cord-002808-84np9brx	70	15	consensus	consensus	NN
cord-002808-84np9brx	70	16	site	site	NN
cord-002808-84np9brx	70	17	(	(	-LRB-
cord-002808-84np9brx	70	18	RTKR	RTKR	NNP
cord-002808-84np9brx	70	19	,	,	,
cord-002808-84np9brx	70	20	residues	residue	NNS
cord-002808-84np9brx	70	21	9	9	CD
cord-002808-84np9brx	70	22	-	-	SYM
cord-002808-84np9brx	70	23	12	12	CD
cord-002808-84np9brx	70	24	for	for	IN
cord-002808-84np9brx	70	25	HPV16	hpv16	ADD
cord-002808-84np9brx	70	26	)	)	-RRB-
cord-002808-84np9brx	70	27	,	,	,
cord-002808-84np9brx	70	28	removing	remove	VBG
cord-002808-84np9brx	70	29	twelve	twelve	CD
cord-002808-84np9brx	70	30	N	n	CD
cord-002808-84np9brx	70	31	-	-	HYPH
cord-002808-84np9brx	70	32	terminal	terminal	NN
cord-002808-84np9brx	70	33	residues	residue	NNS
cord-002808-84np9brx	70	34	of	of	IN
cord-002808-84np9brx	70	35	HPV16	hpv16	NN
cord-002808-84np9brx	70	36	L2	L2	NNP
cord-002808-84np9brx	70	37	[	[	-LRB-
cord-002808-84np9brx	70	38	36	36	CD
cord-002808-84np9brx	70	39	]	]	-RRB-
cord-002808-84np9brx	71	1	(	(	-LRB-
cord-002808-84np9brx	71	2	Figure	figure	NN
cord-002808-84np9brx	71	3	1	1	CD
cord-002808-84np9brx	71	4	)	)	-RRB-
cord-002808-84np9brx	71	5	.	.	.
cord-002808-84np9brx	72	1	The	the	DT
cord-002808-84np9brx	72	2	molecular	molecular	JJ
cord-002808-84np9brx	72	3	basis	basis	NN
cord-002808-84np9brx	72	4	for	for	IN
cord-002808-84np9brx	72	5	the	the	DT
cord-002808-84np9brx	72	6	requirement	requirement	NN
cord-002808-84np9brx	72	7	of	of	IN
cord-002808-84np9brx	72	8	this	this	DT
cord-002808-84np9brx	72	9	cleavage	cleavage	NN
cord-002808-84np9brx	72	10	remains	remain	VBZ
cord-002808-84np9brx	72	11	unknown	unknown	JJ
cord-002808-84np9brx	72	12	,	,	,
cord-002808-84np9brx	72	13	but	but	CC
cord-002808-84np9brx	72	14	inhibition	inhibition	NN
cord-002808-84np9brx	72	15	of	of	IN
cord-002808-84np9brx	72	16	cleavage	cleavage	NN
cord-002808-84np9brx	72	17	through	through	IN
cord-002808-84np9brx	72	18	mutation	mutation	NN
cord-002808-84np9brx	72	19	of	of	IN
cord-002808-84np9brx	72	20	the	the	DT
cord-002808-84np9brx	72	21	cleavage	cleavage	NN
cord-002808-84np9brx	72	22	site	site	NN
cord-002808-84np9brx	72	23	or	or	CC
cord-002808-84np9brx	72	24	by	by	IN
cord-002808-84np9brx	72	25	biochemical	biochemical	JJ
cord-002808-84np9brx	72	26	inhibition	inhibition	NN
cord-002808-84np9brx	72	27	of	of	IN
cord-002808-84np9brx	72	28	furin	furin	NN
cord-002808-84np9brx	72	29	results	result	NNS
cord-002808-84np9brx	72	30	in	in	IN
cord-002808-84np9brx	72	31	aberrant	aberrant	JJ
cord-002808-84np9brx	72	32	trafficking	trafficking	NN
cord-002808-84np9brx	72	33	of	of	IN
cord-002808-84np9brx	72	34	the	the	DT
cord-002808-84np9brx	72	35	L2	L2	NNP
cord-002808-84np9brx	72	36	/	/	SYM
cord-002808-84np9brx	72	37	vDNA	vdna	RB
cord-002808-84np9brx	72	38	complex	complex	JJ
cord-002808-84np9brx	72	39	and	and	CC
cord-002808-84np9brx	72	40	potent	potent	JJ
cord-002808-84np9brx	72	41	abrogation	abrogation	NN
cord-002808-84np9brx	72	42	of	of	IN
cord-002808-84np9brx	72	43	infection	infection	NN
cord-002808-84np9brx	72	44	[	[	-LRB-
cord-002808-84np9brx	72	45	23	23	CD
cord-002808-84np9brx	72	46	]	]	-RRB-
cord-002808-84np9brx	72	47	.	.	.
cord-002808-84np9brx	73	1	Cleavage	cleavage	NN
cord-002808-84np9brx	73	2	appears	appear	VBZ
cord-002808-84np9brx	73	3	to	to	TO
cord-002808-84np9brx	73	4	trigger	trigger	VB
cord-002808-84np9brx	73	5	a	a	DT
cord-002808-84np9brx	73	6	conformational	conformational	JJ
cord-002808-84np9brx	73	7	change	change	NN
cord-002808-84np9brx	73	8	in	in	IN
cord-002808-84np9brx	73	9	capsid	capsid	NN
cord-002808-84np9brx	73	10	and/or	and/or	CC
cord-002808-84np9brx	73	11	L2	L2	NNP
cord-002808-84np9brx	73	12	structure	structure	NN
cord-002808-84np9brx	73	13	,	,	,
cord-002808-84np9brx	73	14	as	as	IN
cord-002808-84np9brx	73	15	the	the	DT
cord-002808-84np9brx	73	16	conserved	conserved	JJ
cord-002808-84np9brx	73	17	and	and	CC
cord-002808-84np9brx	73	18	neutralizing	neutralize	VBG
cord-002808-84np9brx	73	19	RG-1	RG-1	NNP
cord-002808-84np9brx	73	20	epitope	epitope	NN
cord-002808-84np9brx	73	21	(	(	-LRB-
cord-002808-84np9brx	73	22	residues	residue	NNS
cord-002808-84np9brx	73	23	17	17	CD
cord-002808-84np9brx	73	24	-	-	SYM
cord-002808-84np9brx	73	25	36	36	CD
cord-002808-84np9brx	73	26	for	for	IN
cord-002808-84np9brx	73	27	HPV16	hpv16	ADD
cord-002808-84np9brx	73	28	[	[	-LRB-
cord-002808-84np9brx	73	29	37	37	CD
cord-002808-84np9brx	73	30	]	]	-RRB-
cord-002808-84np9brx	73	31	)	)	-RRB-
cord-002808-84np9brx	73	32	becomes	become	VBZ
cord-002808-84np9brx	73	33	accessible	accessible	JJ
cord-002808-84np9brx	73	34	to	to	IN
cord-002808-84np9brx	73	35	antibody	antibody	NN
cord-002808-84np9brx	73	36	staining	stain	VBG
cord-002808-84np9brx	73	37	shortly	shortly	RB
cord-002808-84np9brx	73	38	after	after	IN
cord-002808-84np9brx	73	39	virion	virion	NN
cord-002808-84np9brx	73	40	binding	bind	VBG
cord-002808-84np9brx	73	41	in	in	IN
cord-002808-84np9brx	73	42	a	a	DT
cord-002808-84np9brx	73	43	furin	furin	NN
cord-002808-84np9brx	73	44	-	-	HYPH
cord-002808-84np9brx	73	45	dependent	dependent	JJ
cord-002808-84np9brx	73	46	manner	manner	NN
cord-002808-84np9brx	73	47	[	[	-LRB-
cord-002808-84np9brx	73	48	38	38	CD
cord-002808-84np9brx	73	49	]	]	-RRB-
cord-002808-84np9brx	73	50	.	.	.
cord-002808-84np9brx	74	1	Cell	cell	NN
cord-002808-84np9brx	74	2	surface	surface	NN
cord-002808-84np9brx	74	3	cyclophilins	cyclophilin	NNS
cord-002808-84np9brx	74	4	(	(	-LRB-
cord-002808-84np9brx	74	5	peptidyl	peptidyl	NNP
cord-002808-84np9brx	74	6	-	-	HYPH
cord-002808-84np9brx	74	7	prolyl	prolyl	JJ
cord-002808-84np9brx	74	8	isomerases	isomerase	NNS
cord-002808-84np9brx	74	9	,	,	,
cord-002808-84np9brx	74	10	PPIs	ppi	NNS
cord-002808-84np9brx	74	11	)	)	-RRB-
cord-002808-84np9brx	74	12	also	also	RB
cord-002808-84np9brx	74	13	appear	appear	VBP
cord-002808-84np9brx	74	14	to	to	TO
cord-002808-84np9brx	74	15	modulate	modulate	VB
cord-002808-84np9brx	74	16	the	the	DT
cord-002808-84np9brx	74	17	conformation	conformation	NN
cord-002808-84np9brx	74	18	of	of	IN
cord-002808-84np9brx	74	19	L2	L2	NNP
cord-002808-84np9brx	74	20	,	,	,
cord-002808-84np9brx	74	21	as	as	IN
cord-002808-84np9brx	74	22	RG-1	RG-1	NNP
cord-002808-84np9brx	74	23	epitope	epitope	NN
cord-002808-84np9brx	74	24	exposure	exposure	NN
cord-002808-84np9brx	74	25	is	be	VBZ
cord-002808-84np9brx	74	26	sensitive	sensitive	JJ
cord-002808-84np9brx	74	27	to	to	IN
cord-002808-84np9brx	74	28	cyclosporine	cyclosporine	NNP
cord-002808-84np9brx	74	29	A	A	NNP
cord-002808-84np9brx	74	30	,	,	,
cord-002808-84np9brx	74	31	a	a	DT
cord-002808-84np9brx	74	32	broad	broad	JJ
cord-002808-84np9brx	74	33	PPI	PPI	NNP
cord-002808-84np9brx	74	34	inhibitor	inhibitor	NN
cord-002808-84np9brx	74	35	[	[	-LRB-
cord-002808-84np9brx	74	36	39	39	CD
cord-002808-84np9brx	74	37	]	]	-RRB-
cord-002808-84np9brx	74	38	.	.	.
cord-002808-84np9brx	75	1	RG-1	RG-1	NNP
cord-002808-84np9brx	76	1	epitope	epitope	NN
cord-002808-84np9brx	76	2	exposure	exposure	NN
cord-002808-84np9brx	76	3	was	be	VBD
cord-002808-84np9brx	76	4	initially	initially	RB
cord-002808-84np9brx	76	5	believed	believe	VBN
cord-002808-84np9brx	76	6	to	to	TO
cord-002808-84np9brx	76	7	be	be	VB
cord-002808-84np9brx	76	8	a	a	DT
cord-002808-84np9brx	76	9	convenient	convenient	JJ
cord-002808-84np9brx	76	10	marker	marker	NN
cord-002808-84np9brx	76	11	for	for	IN
cord-002808-84np9brx	76	12	furin	furin	NN
cord-002808-84np9brx	76	13	cleavage	cleavage	NN
cord-002808-84np9brx	76	14	,	,	,
cord-002808-84np9brx	76	15	and	and	CC
cord-002808-84np9brx	76	16	cyclophilins	cyclophilins	NNP
cord-002808-84np9brx	76	17	were	be	VBD
cord-002808-84np9brx	76	18	believed	believe	VBN
cord-002808-84np9brx	76	19	to	to	TO
cord-002808-84np9brx	76	20	control	control	VB
cord-002808-84np9brx	76	21	L2	L2	NNP
cord-002808-84np9brx	76	22	accessibility	accessibility	NN
cord-002808-84np9brx	76	23	and	and	CC
cord-002808-84np9brx	76	24	susceptibility	susceptibility	NN
cord-002808-84np9brx	76	25	to	to	IN
cord-002808-84np9brx	76	26	furin	furin	NN
cord-002808-84np9brx	76	27	,	,	,
cord-002808-84np9brx	76	28	but	but	CC
cord-002808-84np9brx	76	29	recent	recent	JJ
cord-002808-84np9brx	76	30	work	work	NN
cord-002808-84np9brx	76	31	disfavors	disfavor	VBZ
cord-002808-84np9brx	76	32	this	this	DT
cord-002808-84np9brx	76	33	idea	idea	NN
cord-002808-84np9brx	76	34	,	,	,
cord-002808-84np9brx	76	35	as	as	IN
cord-002808-84np9brx	76	36	furin	furin	NN
cord-002808-84np9brx	76	37	cleavage	cleavage	NN
cord-002808-84np9brx	76	38	still	still	RB
cord-002808-84np9brx	76	39	occurs	occur	VBZ
cord-002808-84np9brx	76	40	despite	despite	IN
cord-002808-84np9brx	76	41	PPI	PPI	NNP
cord-002808-84np9brx	76	42	inhibition	inhibition	NN
cord-002808-84np9brx	76	43	of	of	IN
cord-002808-84np9brx	76	44	RG-1	RG-1	NNP
cord-002808-84np9brx	76	45	exposure	exposure	NN
cord-002808-84np9brx	76	46	[	[	-LRB-
cord-002808-84np9brx	76	47	36	36	CD
cord-002808-84np9brx	76	48	]	]	-RRB-
cord-002808-84np9brx	76	49	.	.	.
cord-002808-84np9brx	77	1	Thus	thus	RB
cord-002808-84np9brx	77	2	,	,	,
cord-002808-84np9brx	77	3	while	while	IN
cord-002808-84np9brx	77	4	RG-1	RG-1	NNP
cord-002808-84np9brx	77	5	staining	staining	NN
cord-002808-84np9brx	77	6	is	be	VBZ
cord-002808-84np9brx	77	7	a	a	DT
cord-002808-84np9brx	77	8	convenient	convenient	JJ
cord-002808-84np9brx	77	9	marker	marker	NN
cord-002808-84np9brx	77	10	for	for	IN
cord-002808-84np9brx	77	11	an	an	DT
cord-002808-84np9brx	77	12	L2	L2	NNP
cord-002808-84np9brx	77	13	conformational	conformational	JJ
cord-002808-84np9brx	77	14	change	change	NN
cord-002808-84np9brx	77	15	that	that	WDT
cord-002808-84np9brx	77	16	is	be	VBZ
cord-002808-84np9brx	77	17	both	both	DT
cord-002808-84np9brx	77	18	furin	furin	NN
cord-002808-84np9brx	77	19	-	-	HYPH
cord-002808-84np9brx	77	20	and	and	CC
cord-002808-84np9brx	77	21	cyclophilin	cyclophilin	NN
cord-002808-84np9brx	77	22	-	-	HYPH
cord-002808-84np9brx	77	23	dependent	dependent	JJ
cord-002808-84np9brx	77	24	,	,	,
cord-002808-84np9brx	77	25	it	-PRON-	PRP
cord-002808-84np9brx	77	26	is	be	VBZ
cord-002808-84np9brx	77	27	not	not	RB
cord-002808-84np9brx	77	28	a	a	DT
cord-002808-84np9brx	77	29	direct	direct	JJ
cord-002808-84np9brx	77	30	readout	readout	NN
cord-002808-84np9brx	77	31	for	for	IN
cord-002808-84np9brx	77	32	furin	furin	NN
cord-002808-84np9brx	77	33	proteolysis	proteolysis	NN
cord-002808-84np9brx	77	34	of	of	IN
cord-002808-84np9brx	77	35	L2	L2	NNP
cord-002808-84np9brx	77	36	,	,	,
cord-002808-84np9brx	77	37	as	as	IN
cord-002808-84np9brx	77	38	cleavage	cleavage	NN
cord-002808-84np9brx	77	39	can	can	MD
cord-002808-84np9brx	77	40	occur	occur	VB
cord-002808-84np9brx	77	41	without	without	IN
cord-002808-84np9brx	77	42	RG-1	RG-1	NNP
cord-002808-84np9brx	77	43	exposure	exposure	NN
cord-002808-84np9brx	77	44	.	.	.
cord-002808-84np9brx	78	1	Shortly	shortly	RB
cord-002808-84np9brx	78	2	after	after	IN
cord-002808-84np9brx	78	3	entry	entry	NN
cord-002808-84np9brx	78	4	,	,	,
cord-002808-84np9brx	78	5	early	early	JJ
cord-002808-84np9brx	78	6	trafficking	trafficking	NN
cord-002808-84np9brx	78	7	of	of	IN
cord-002808-84np9brx	78	8	HPV	HPV	NNP
cord-002808-84np9brx	78	9	is	be	VBZ
cord-002808-84np9brx	78	10	modulated	modulate	VBN
cord-002808-84np9brx	78	11	by	by	IN
cord-002808-84np9brx	78	12	the	the	DT
cord-002808-84np9brx	78	13	tetraspanin	tetraspanin	NNP
cord-002808-84np9brx	78	14	CD63	CD63	NNP
cord-002808-84np9brx	78	15	and	and	CC
cord-002808-84np9brx	78	16	its	-PRON-	PRP$
cord-002808-84np9brx	78	17	partners	partner	NNS
cord-002808-84np9brx	79	1	syntenin	syntenin	NNP
cord-002808-84np9brx	79	2	/	/	SYM
cord-002808-84np9brx	79	3	ALIX	ALIX	NNP
cord-002808-84np9brx	79	4	[	[	-LRB-
cord-002808-84np9brx	79	5	40	40	CD
cord-002808-84np9brx	79	6	]	]	-RRB-
cord-002808-84np9brx	79	7	.	.	.
cord-002808-84np9brx	80	1	These	these	DT
cord-002808-84np9brx	80	2	molecules	molecule	NNS
cord-002808-84np9brx	80	3	are	be	VBP
cord-002808-84np9brx	80	4	necessary	necessary	JJ
cord-002808-84np9brx	80	5	for	for	IN
cord-002808-84np9brx	80	6	sorting	sort	VBG
cord-002808-84np9brx	80	7	of	of	IN
cord-002808-84np9brx	80	8	HPV	hpv	NN
cord-002808-84np9brx	80	9	virions	virion	NNS
cord-002808-84np9brx	80	10	from	from	IN
cord-002808-84np9brx	80	11	early	early	JJ
cord-002808-84np9brx	80	12	endosomes	endosome	NNS
cord-002808-84np9brx	80	13	(	(	-LRB-
cord-002808-84np9brx	80	14	EE	EE	NNP
cord-002808-84np9brx	80	15	)	)	-RRB-
cord-002808-84np9brx	80	16	into	into	IN
cord-002808-84np9brx	80	17	acidic	acidic	JJ
cord-002808-84np9brx	80	18	late	late	JJ
cord-002808-84np9brx	80	19	endosome	endosome	NN
cord-002808-84np9brx	80	20	(	(	-LRB-
cord-002808-84np9brx	80	21	LE	LE	NNP
cord-002808-84np9brx	80	22	)	)	-RRB-
cord-002808-84np9brx	80	23	and	and	CC
cord-002808-84np9brx	80	24	multivesicular	multivesicular	NNP
cord-002808-84np9brx	80	25	bodies	body	NNS
cord-002808-84np9brx	80	26	(	(	-LRB-
cord-002808-84np9brx	80	27	MVBs	MVBs	NNP
cord-002808-84np9brx	80	28	)	)	-RRB-
cord-002808-84np9brx	80	29	,	,	,
cord-002808-84np9brx	80	30	a	a	DT
cord-002808-84np9brx	80	31	prerequisite	prerequisite	NN
cord-002808-84np9brx	80	32	for	for	IN
cord-002808-84np9brx	80	33	capsid	capsid	NN
cord-002808-84np9brx	80	34	disassembly	disassembly	NN
cord-002808-84np9brx	80	35	,	,	,
cord-002808-84np9brx	80	36	uncoating	uncoating	NN
cord-002808-84np9brx	80	37	,	,	,
cord-002808-84np9brx	80	38	and	and	CC
cord-002808-84np9brx	80	39	segregation	segregation	NN
cord-002808-84np9brx	80	40	of	of	IN
cord-002808-84np9brx	80	41	L2	l2	NN
cord-002808-84np9brx	80	42	/	/	,
cord-002808-84np9brx	80	43	vDNA	vdna	NN
cord-002808-84np9brx	80	44	from	from	IN
cord-002808-84np9brx	80	45	L1	L1	NNP
cord-002808-84np9brx	80	46	(	(	-LRB-
cord-002808-84np9brx	80	47	Figure	figure	NN
cord-002808-84np9brx	80	48	2	2	CD
cord-002808-84np9brx	80	49	)	)	-RRB-
cord-002808-84np9brx	80	50	.	.	.
cord-002808-84np9brx	81	1	When	when	WRB
cord-002808-84np9brx	81	2	MVB	MVB	NNP
cord-002808-84np9brx	81	3	trafficking	trafficking	NN
cord-002808-84np9brx	81	4	of	of	IN
cord-002808-84np9brx	81	5	HPV	HPV	NNP
cord-002808-84np9brx	81	6	was	be	VBD
cord-002808-84np9brx	81	7	interrupted	interrupt	VBN
cord-002808-84np9brx	81	8	by	by	IN
cord-002808-84np9brx	81	9	knockdown	knockdown	NN
cord-002808-84np9brx	81	10	of	of	IN
cord-002808-84np9brx	81	11	either	either	DT
cord-002808-84np9brx	81	12	CD63	CD63	NNP
cord-002808-84np9brx	81	13	or	or	CC
cord-002808-84np9brx	81	14	syntenin	syntenin	NNP
cord-002808-84np9brx	81	15	,	,	,
cord-002808-84np9brx	81	16	subcellular	subcellular	JJ
cord-002808-84np9brx	81	17	transport	transport	NN
cord-002808-84np9brx	81	18	of	of	IN
cord-002808-84np9brx	81	19	L2	l2	NN
cord-002808-84np9brx	81	20	/	/	,
cord-002808-84np9brx	81	21	vDNA	vDNA	JJS
cord-002808-84np9brx	81	22	Viruses	virus	NNS
cord-002808-84np9brx	81	23	2017	2017	CD
cord-002808-84np9brx	81	24	,	,	,
cord-002808-84np9brx	81	25	9	9	CD
cord-002808-84np9brx	81	26	,	,	,
cord-002808-84np9brx	81	27	370	370	CD
cord-002808-84np9brx	81	28	4	4	CD
cord-002808-84np9brx	81	29	of	of	IN
cord-002808-84np9brx	81	30	18	18	CD
cord-002808-84np9brx	81	31	was	be	VBD
cord-002808-84np9brx	81	32	altered	alter	VBN
cord-002808-84np9brx	81	33	and	and	CC
cord-002808-84np9brx	81	34	infection	infection	NN
cord-002808-84np9brx	81	35	was	be	VBD
cord-002808-84np9brx	81	36	partially	partially	RB
cord-002808-84np9brx	81	37	blocked	block	VBN
cord-002808-84np9brx	81	38	,	,	,
cord-002808-84np9brx	81	39	demonstrating	demonstrate	VBG
cord-002808-84np9brx	81	40	a	a	DT
cord-002808-84np9brx	81	41	requirement	requirement	NN
cord-002808-84np9brx	81	42	for	for	IN
cord-002808-84np9brx	81	43	virion	virion	NN
cord-002808-84np9brx	81	44	transport	transport	NN
cord-002808-84np9brx	81	45	into	into	IN
cord-002808-84np9brx	81	46	MVBs	mvb	NNS
cord-002808-84np9brx	81	47	[	[	-LRB-
cord-002808-84np9brx	81	48	40	40	CD
cord-002808-84np9brx	81	49	]	]	-RRB-
cord-002808-84np9brx	81	50	.	.	.
cord-002808-84np9brx	82	1	Accordingly	accordingly	RB
cord-002808-84np9brx	82	2	,	,	,
cord-002808-84np9brx	82	3	components	component	NNS
cord-002808-84np9brx	82	4	of	of	IN
cord-002808-84np9brx	82	5	the	the	DT
cord-002808-84np9brx	82	6	ESCRT	ESCRT	NNP
cord-002808-84np9brx	82	7	machinery	machinery	NN
cord-002808-84np9brx	82	8	,	,	,
cord-002808-84np9brx	82	9	a	a	DT
cord-002808-84np9brx	82	10	group	group	NN
cord-002808-84np9brx	82	11	of	of	IN
cord-002808-84np9brx	82	12	cytosolic	cytosolic	JJ
cord-002808-84np9brx	82	13	multisubunit	multisubunit	NNP
cord-002808-84np9brx	82	14	complexes	complex	NNS
cord-002808-84np9brx	82	15	that	that	WDT
cord-002808-84np9brx	82	16	facilitate	facilitate	VBP
cord-002808-84np9brx	82	17	endosomal	endosomal	JJ
cord-002808-84np9brx	82	18	maturation	maturation	NN
cord-002808-84np9brx	82	19	and	and	CC
cord-002808-84np9brx	82	20	MVB	MVB	NNP
cord-002808-84np9brx	82	21	biogenesis	biogenesis	NN
cord-002808-84np9brx	82	22	,	,	,
cord-002808-84np9brx	82	23	are	be	VBP
cord-002808-84np9brx	82	24	involved	involve	VBN
cord-002808-84np9brx	82	25	in	in	IN
cord-002808-84np9brx	82	26	efficient	efficient	JJ
cord-002808-84np9brx	82	27	HPV	hpv	NN
cord-002808-84np9brx	82	28	infection	infection	NN
cord-002808-84np9brx	82	29	[	[	-LRB-
cord-002808-84np9brx	82	30	41	41	CD
cord-002808-84np9brx	82	31	,	,	,
cord-002808-84np9brx	82	32	42	42	CD
cord-002808-84np9brx	82	33	]	]	-RRB-
cord-002808-84np9brx	82	34	.	.	.
cord-002808-84np9brx	83	1	Endosomal	Endosomal	NNP
cord-002808-84np9brx	83	2	acidification	acidification	NN
cord-002808-84np9brx	83	3	is	be	VBZ
cord-002808-84np9brx	83	4	a	a	DT
cord-002808-84np9brx	83	5	strict	strict	JJ
cord-002808-84np9brx	83	6	requirement	requirement	NN
cord-002808-84np9brx	83	7	for	for	IN
cord-002808-84np9brx	83	8	HPV	hpv	NN
cord-002808-84np9brx	83	9	infection	infection	NN
cord-002808-84np9brx	83	10	[	[	-LRB-
cord-002808-84np9brx	83	11	24	24	CD
cord-002808-84np9brx	83	12	,	,	,
cord-002808-84np9brx	83	13	43	43	CD
cord-002808-84np9brx	83	14	,	,	,
cord-002808-84np9brx	83	15	44	44	CD
cord-002808-84np9brx	83	16	]	]	-RRB-
cord-002808-84np9brx	83	17	,	,	,
cord-002808-84np9brx	83	18	but	but	CC
cord-002808-84np9brx	83	19	it	-PRON-	PRP
cord-002808-84np9brx	83	20	remains	remain	VBZ
cord-002808-84np9brx	83	21	unclear	unclear	JJ
cord-002808-84np9brx	83	22	if	if	IN
cord-002808-84np9brx	83	23	it	-PRON-	PRP
cord-002808-84np9brx	83	24	is	be	VBZ
cord-002808-84np9brx	83	25	simply	simply	RB
cord-002808-84np9brx	83	26	needed	need	VBN
cord-002808-84np9brx	83	27	for	for	IN
cord-002808-84np9brx	83	28	proper	proper	JJ
cord-002808-84np9brx	83	29	endosomal	endosomal	JJ
cord-002808-84np9brx	83	30	maturation	maturation	NN
cord-002808-84np9brx	83	31	and	and	CC
cord-002808-84np9brx	83	32	MVB	MVB	NNP
cord-002808-84np9brx	83	33	biogenesis	biogenesis	NN
cord-002808-84np9brx	83	34	,	,	,
cord-002808-84np9brx	83	35	or	or	CC
cord-002808-84np9brx	83	36	if	if	IN
cord-002808-84np9brx	83	37	acidification	acidification	NN
cord-002808-84np9brx	83	38	itself	-PRON-	PRP
cord-002808-84np9brx	83	39	also	also	RB
cord-002808-84np9brx	83	40	triggers	trigger	VBZ
cord-002808-84np9brx	83	41	conformational	conformational	JJ
cord-002808-84np9brx	83	42	changes	change	NNS
cord-002808-84np9brx	83	43	in	in	IN
cord-002808-84np9brx	83	44	the	the	DT
cord-002808-84np9brx	83	45	HPV	HPV	NNP
cord-002808-84np9brx	83	46	capsid	capsid	NN
cord-002808-84np9brx	83	47	or	or	CC
cord-002808-84np9brx	83	48	host	host	NN
cord-002808-84np9brx	83	49	proteins	protein	NNS
cord-002808-84np9brx	83	50	that	that	WDT
cord-002808-84np9brx	83	51	are	be	VBP
cord-002808-84np9brx	83	52	required	require	VBN
cord-002808-84np9brx	83	53	for	for	IN
cord-002808-84np9brx	83	54	downstream	downstream	JJ
cord-002808-84np9brx	83	55	processes	process	NNS
cord-002808-84np9brx	83	56	like	like	IN
cord-002808-84np9brx	83	57	capsid	capsid	NN
cord-002808-84np9brx	83	58	uncoating	uncoating	NN
cord-002808-84np9brx	83	59	and	and	CC
cord-002808-84np9brx	83	60	vDNA	vdna	IN
cord-002808-84np9brx	83	61	trafficking	trafficking	NN
cord-002808-84np9brx	83	62	.	.	.
cord-002808-84np9brx	84	1	Acid	acid	NN
cord-002808-84np9brx	84	2	-	-	HYPH
cord-002808-84np9brx	84	3	dependent	dependent	JJ
cord-002808-84np9brx	84	4	cathepsin	cathepsin	NN
cord-002808-84np9brx	84	5	proteases	protease	NNS
cord-002808-84np9brx	84	6	further	far	RBR
cord-002808-84np9brx	84	7	cleave	cleave	VBP
cord-002808-84np9brx	84	8	and	and	CC
cord-002808-84np9brx	84	9	process	process	VB
cord-002808-84np9brx	84	10	the	the	DT
cord-002808-84np9brx	84	11	L1	L1	NNP
cord-002808-84np9brx	84	12	capsid	capsid	NN
cord-002808-84np9brx	84	13	within	within	IN
cord-002808-84np9brx	84	14	the	the	DT
cord-002808-84np9brx	84	15	endolysosomal	endolysosomal	JJ
cord-002808-84np9brx	84	16	compartments	compartment	NNS
cord-002808-84np9brx	84	17	.	.	.
cord-002808-84np9brx	85	1	Capsid	capsid	JJ
cord-002808-84np9brx	85	2	proteolysis	proteolysis	NN
cord-002808-84np9brx	85	3	and	and	CC
cord-002808-84np9brx	85	4	disassembly	disassembly	NN
cord-002808-84np9brx	85	5	can	can	MD
cord-002808-84np9brx	85	6	be	be	VB
cord-002808-84np9brx	85	7	visualized	visualize	VBN
cord-002808-84np9brx	85	8	by	by	IN
cord-002808-84np9brx	85	9	immunofluorescence	immunofluorescence	NN
cord-002808-84np9brx	85	10	with	with	IN
cord-002808-84np9brx	85	11	the	the	DT
cord-002808-84np9brx	85	12	monoclonal	monoclonal	JJ
cord-002808-84np9brx	85	13	antibody	antibody	NN
cord-002808-84np9brx	85	14	L1	L1	NNP
cord-002808-84np9brx	85	15	-	-	HYPH
cord-002808-84np9brx	85	16	7	7	CD
cord-002808-84np9brx	85	17	[	[	-LRB-
cord-002808-84np9brx	85	18	45	45	CD
cord-002808-84np9brx	85	19	]	]	-RRB-
cord-002808-84np9brx	85	20	,	,	,
cord-002808-84np9brx	85	21	specific	specific	JJ
cord-002808-84np9brx	85	22	for	for	IN
cord-002808-84np9brx	85	23	L1	L1	NNP
cord-002808-84np9brx	85	24	residues	residue	NNS
cord-002808-84np9brx	85	25	303	303	CD
cord-002808-84np9brx	85	26	-	-	HYPH
cord-002808-84np9brx	85	27	313	313	CD
cord-002808-84np9brx	85	28	,	,	,
cord-002808-84np9brx	85	29	located	locate	VBN
cord-002808-84np9brx	85	30	in	in	IN
cord-002808-84np9brx	85	31	central	central	JJ
cord-002808-84np9brx	85	32	cavities	cavity	NNS
cord-002808-84np9brx	85	33	underneath	underneath	IN
cord-002808-84np9brx	85	34	each	each	DT
cord-002808-84np9brx	85	35	of	of	IN
cord-002808-84np9brx	85	36	the	the	DT
cord-002808-84np9brx	85	37	L1	L1	NNP
cord-002808-84np9brx	85	38	pentamers	pentamer	NNS
cord-002808-84np9brx	85	39	.	.	.
cord-002808-84np9brx	86	1	This	this	DT
cord-002808-84np9brx	86	2	region	region	NN
cord-002808-84np9brx	86	3	is	be	VBZ
cord-002808-84np9brx	86	4	only	only	RB
cord-002808-84np9brx	86	5	available	available	JJ
cord-002808-84np9brx	86	6	for	for	IN
cord-002808-84np9brx	86	7	binding	bind	VBG
cord-002808-84np9brx	86	8	to	to	IN
cord-002808-84np9brx	86	9	L1	L1	NNP
cord-002808-84np9brx	86	10	-	-	HYPH
cord-002808-84np9brx	86	11	7	7	NNP
cord-002808-84np9brx	86	12	after	after	IN
cord-002808-84np9brx	86	13	capsid	capsid	NN
cord-002808-84np9brx	86	14	disassembly	disassembly	NN
cord-002808-84np9brx	86	15	;	;	:
cord-002808-84np9brx	86	16	around	around	IN
cord-002808-84np9brx	86	17	8	8	CD
cord-002808-84np9brx	86	18	h	h	NN
cord-002808-84np9brx	86	19	post	post	NN
cord-002808-84np9brx	86	20	infection	infection	NN
cord-002808-84np9brx	86	21	[	[	-LRB-
cord-002808-84np9brx	86	22	28	28	CD
cord-002808-84np9brx	86	23	]	]	-RRB-
cord-002808-84np9brx	86	24	.	.	.
cord-002808-84np9brx	87	1	While	while	IN
cord-002808-84np9brx	87	2	useful	useful	JJ
cord-002808-84np9brx	87	3	for	for	IN
cord-002808-84np9brx	87	4	marking	mark	VBG
cord-002808-84np9brx	87	5	capsid	capsid	NN
cord-002808-84np9brx	87	6	disassembly	disassembly	NN
cord-002808-84np9brx	87	7	,	,	,
cord-002808-84np9brx	87	8	L1	L1	NNP
cord-002808-84np9brx	87	9	-	-	HYPH
cord-002808-84np9brx	87	10	7	7	CD
cord-002808-84np9brx	87	11	reactivity	reactivity	NN
cord-002808-84np9brx	87	12	does	do	VBZ
cord-002808-84np9brx	87	13	not	not	RB
cord-002808-84np9brx	87	14	reveal	reveal	VB
cord-002808-84np9brx	87	15	true	true	JJ
cord-002808-84np9brx	87	16	infectious	infectious	JJ
cord-002808-84np9brx	87	17	uncoating	uncoating	NN
cord-002808-84np9brx	87	18	,	,	,
cord-002808-84np9brx	87	19	as	as	IN
cord-002808-84np9brx	87	20	staining	staining	NN
cord-002808-84np9brx	87	21	is	be	VBZ
cord-002808-84np9brx	87	22	blocked	block	VBN
cord-002808-84np9brx	87	23	by	by	IN
cord-002808-84np9brx	87	24	cathepsin	cathepsin	NN
cord-002808-84np9brx	87	25	inhibitors	inhibitor	NNS
cord-002808-84np9brx	87	26	with	with	IN
cord-002808-84np9brx	87	27	no	no	DT
cord-002808-84np9brx	87	28	effect	effect	NN
cord-002808-84np9brx	87	29	on	on	IN
cord-002808-84np9brx	87	30	infectivity	infectivity	NN
cord-002808-84np9brx	87	31	[	[	-LRB-
cord-002808-84np9brx	87	32	22	22	CD
cord-002808-84np9brx	87	33	]	]	-RRB-
cord-002808-84np9brx	87	34	.	.	.
cord-002808-84np9brx	88	1	Within	within	IN
cord-002808-84np9brx	88	2	LE	LE	NNP
cord-002808-84np9brx	88	3	/	/	SYM
cord-002808-84np9brx	88	4	MVBs	MVBs	NNP
cord-002808-84np9brx	88	5	the	the	DT
cord-002808-84np9brx	88	6	L2	L2	NNP
cord-002808-84np9brx	88	7	/	/	SYM
cord-002808-84np9brx	88	8	vDNA	vdna	NN
cord-002808-84np9brx	88	9	complex	complex	NNP
cord-002808-84np9brx	88	10	segregates	segregate	VBZ
cord-002808-84np9brx	88	11	away	away	RB
cord-002808-84np9brx	88	12	from	from	IN
cord-002808-84np9brx	88	13	the	the	DT
cord-002808-84np9brx	88	14	partially	partially	RB
cord-002808-84np9brx	88	15	degraded	degrade	VBN
cord-002808-84np9brx	88	16	L1	L1	NNP
cord-002808-84np9brx	88	17	capsid	capsid	NN
cord-002808-84np9brx	88	18	in	in	IN
cord-002808-84np9brx	88	19	a	a	DT
cord-002808-84np9brx	88	20	cyclophilin	cyclophilin	JJ
cord-002808-84np9brx	88	21	-	-	HYPH
cord-002808-84np9brx	88	22	dependent	dependent	JJ
cord-002808-84np9brx	88	23	manner	manner	NN
cord-002808-84np9brx	88	24	[	[	-LRB-
cord-002808-84np9brx	88	25	46	46	CD
cord-002808-84np9brx	88	26	]	]	-RRB-
cord-002808-84np9brx	88	27	.	.	.
cord-002808-84np9brx	89	1	The	the	DT
cord-002808-84np9brx	89	2	complex	complex	NN
cord-002808-84np9brx	89	3	then	then	RB
cord-002808-84np9brx	89	4	traffics	traffic	VBZ
cord-002808-84np9brx	89	5	to	to	IN
cord-002808-84np9brx	89	6	the	the	DT
cord-002808-84np9brx	89	7	trans	trans	NNP
cord-002808-84np9brx	89	8	-	-	NNP
cord-002808-84np9brx	89	9	Golgi	Golgi	NNP
cord-002808-84np9brx	89	10	network	network	NN
cord-002808-84np9brx	89	11	(	(	-LRB-
cord-002808-84np9brx	89	12	TGN	TGN	NNP
cord-002808-84np9brx	89	13	)	)	-RRB-
cord-002808-84np9brx	89	14	in	in	IN
cord-002808-84np9brx	89	15	a	a	DT
cord-002808-84np9brx	89	16	retromer	retromer	NN
cord-002808-84np9brx	89	17	-	-	HYPH
cord-002808-84np9brx	89	18	dependent	dependent	JJ
cord-002808-84np9brx	89	19	manner	manner	NN
cord-002808-84np9brx	89	20	[	[	-LRB-
cord-002808-84np9brx	89	21	23	23	CD
cord-002808-84np9brx	89	22	,	,	,
cord-002808-84np9brx	89	23	47	47	CD
cord-002808-84np9brx	89	24	,	,	,
cord-002808-84np9brx	89	25	48	48	CD
cord-002808-84np9brx	89	26	]	]	-RRB-
cord-002808-84np9brx	89	27	,	,	,
cord-002808-84np9brx	89	28	where	where	WRB
cord-002808-84np9brx	89	29	it	-PRON-	PRP
cord-002808-84np9brx	89	30	resides	reside	VBZ
cord-002808-84np9brx	89	31	until	until	IN
cord-002808-84np9brx	89	32	the	the	DT
cord-002808-84np9brx	89	33	onset	onset	NN
cord-002808-84np9brx	89	34	of	of	IN
cord-002808-84np9brx	89	35	mitosis	mitosis	NN
cord-002808-84np9brx	89	36	[	[	-LRB-
cord-002808-84np9brx	89	37	49	49	CD
cord-002808-84np9brx	89	38	]	]	-RRB-
cord-002808-84np9brx	90	1	[	[	-LRB-
cord-002808-84np9brx	90	2	50	50	CD
cord-002808-84np9brx	90	3	]	]	-RRB-
cord-002808-84np9brx	90	4	[	[	-LRB-
cord-002808-84np9brx	90	5	51	51	CD
cord-002808-84np9brx	90	6	]	]	-RRB-
cord-002808-84np9brx	90	7	.	.	.
cord-002808-84np9brx	91	1	Recent	recent	JJ
cord-002808-84np9brx	91	2	work	work	NN
cord-002808-84np9brx	91	3	has	have	VBZ
cord-002808-84np9brx	91	4	shown	show	VBN
cord-002808-84np9brx	91	5	that	that	IN
cord-002808-84np9brx	91	6	a	a	DT
cord-002808-84np9brx	91	7	fraction	fraction	NN
cord-002808-84np9brx	91	8	of	of	IN
cord-002808-84np9brx	91	9	the	the	DT
cord-002808-84np9brx	91	10	L1	L1	NNP
cord-002808-84np9brx	91	11	capsid	capsid	NN
cord-002808-84np9brx	91	12	,	,	,
cord-002808-84np9brx	91	13	in	in	IN
cord-002808-84np9brx	91	14	the	the	DT
cord-002808-84np9brx	91	15	form	form	NN
cord-002808-84np9brx	91	16	of	of	IN
cord-002808-84np9brx	91	17	conformationally	conformationally	RB
cord-002808-84np9brx	91	18	intact	intact	JJ
cord-002808-84np9brx	91	19	pentamers	pentamer	NNS
cord-002808-84np9brx	91	20	,	,	,
cord-002808-84np9brx	91	21	accompanies	accompany	VBZ
cord-002808-84np9brx	91	22	the	the	DT
cord-002808-84np9brx	91	23	L2	L2	NNP
cord-002808-84np9brx	91	24	/	/	,
cord-002808-84np9brx	91	25	vDNA	vdna	RB
cord-002808-84np9brx	91	26	complex	complex	JJ
cord-002808-84np9brx	91	27	to	to	IN
cord-002808-84np9brx	91	28	the	the	DT
cord-002808-84np9brx	91	29	TGN	TGN	NNP
cord-002808-84np9brx	91	30	and	and	CC
cord-002808-84np9brx	91	31	nucleus	nucleus	NN
cord-002808-84np9brx	91	32	,	,	,
cord-002808-84np9brx	91	33	but	but	CC
cord-002808-84np9brx	91	34	a	a	DT
cord-002808-84np9brx	91	35	functional	functional	JJ
cord-002808-84np9brx	91	36	role	role	NN
cord-002808-84np9brx	91	37	for	for	IN
cord-002808-84np9brx	91	38	these	these	DT
cord-002808-84np9brx	91	39	L1	L1	NNP
cord-002808-84np9brx	91	40	pentamers	pentamer	NNS
cord-002808-84np9brx	91	41	remains	remain	VBZ
cord-002808-84np9brx	91	42	unclear	unclear	JJ
cord-002808-84np9brx	91	43	[	[	-LRB-
cord-002808-84np9brx	91	44	52	52	CD
cord-002808-84np9brx	91	45	]	]	-RRB-
cord-002808-84np9brx	91	46	.	.	.
cord-002808-84np9brx	92	1	Colocalization	Colocalization	NNP
cord-002808-84np9brx	92	2	of	of	IN
cord-002808-84np9brx	92	3	L2	L2	NNP
cord-002808-84np9brx	92	4	/	/	,
cord-002808-84np9brx	92	5	vDNA	vdna	NN
cord-002808-84np9brx	92	6	with	with	IN
cord-002808-84np9brx	92	7	TGN	TGN	NNP
cord-002808-84np9brx	92	8	markers	marker	NNS
cord-002808-84np9brx	92	9	is	be	VBZ
cord-002808-84np9brx	92	10	well	well	RB
cord-002808-84np9brx	92	11	established	establish	VBN
cord-002808-84np9brx	92	12	,	,	,
cord-002808-84np9brx	92	13	but	but	CC
cord-002808-84np9brx	92	14	several	several	JJ
cord-002808-84np9brx	92	15	groups	group	NNS
cord-002808-84np9brx	92	16	have	have	VBP
cord-002808-84np9brx	92	17	reported	report	VBN
cord-002808-84np9brx	92	18	transport	transport	NN
cord-002808-84np9brx	92	19	of	of	IN
cord-002808-84np9brx	92	20	vDNA	vdna	DT
cord-002808-84np9brx	92	21	to	to	TO
cord-002808-84np9brx	92	22	more	more	RBR
cord-002808-84np9brx	92	23	distal	distal	JJ
cord-002808-84np9brx	92	24	retrograde	retrograde	JJ
cord-002808-84np9brx	92	25	sites	site	NNS
cord-002808-84np9brx	92	26	.	.	.
cord-002808-84np9brx	93	1	Partial	partial	JJ
cord-002808-84np9brx	93	2	colocalization	colocalization	NN
cord-002808-84np9brx	93	3	of	of	IN
cord-002808-84np9brx	93	4	vDNA	vdna	DT
cord-002808-84np9brx	93	5	with	with	IN
cord-002808-84np9brx	93	6	cis	cis	NNP
cord-002808-84np9brx	93	7	/	/	SYM
cord-002808-84np9brx	93	8	medial	medial	JJ
cord-002808-84np9brx	93	9	-	-	HYPH
cord-002808-84np9brx	93	10	Golgi	Golgi	NNP
cord-002808-84np9brx	93	11	markers	marker	NNS
cord-002808-84np9brx	93	12	like	like	IN
cord-002808-84np9brx	93	13	GM130	GM130	NNP
cord-002808-84np9brx	93	14	and	and	CC
cord-002808-84np9brx	93	15	giantin	giantin	NNP
cord-002808-84np9brx	93	16	has	have	VBZ
cord-002808-84np9brx	93	17	been	be	VBN
cord-002808-84np9brx	93	18	reported	report	VBN
cord-002808-84np9brx	93	19	[	[	-LRB-
cord-002808-84np9brx	93	20	23	23	CD
cord-002808-84np9brx	93	21	,	,	,
cord-002808-84np9brx	93	22	53	53	CD
cord-002808-84np9brx	93	23	]	]	-RRB-
cord-002808-84np9brx	93	24	.	.	.
cord-002808-84np9brx	94	1	Likewise	likewise	RB
cord-002808-84np9brx	94	2	,	,	,
cord-002808-84np9brx	94	3	sensitive	sensitive	JJ
cord-002808-84np9brx	94	4	techniques	technique	NNS
cord-002808-84np9brx	94	5	like	like	IN
cord-002808-84np9brx	94	6	the	the	DT
cord-002808-84np9brx	94	7	proximity	proximity	NN
cord-002808-84np9brx	94	8	ligation	ligation	NN
cord-002808-84np9brx	94	9	assay	assay	NN
cord-002808-84np9brx	94	10	[	[	-LRB-
cord-002808-84np9brx	94	11	54	54	CD
cord-002808-84np9brx	94	12	]	]	-RRB-
cord-002808-84np9brx	94	13	have	have	VBP
cord-002808-84np9brx	94	14	suggested	suggest	VBN
cord-002808-84np9brx	94	15	that	that	IN
cord-002808-84np9brx	94	16	L2	L2	NNP
cord-002808-84np9brx	94	17	/	/	SYM
cord-002808-84np9brx	94	18	vDNA	vdna	JJ
cord-002808-84np9brx	94	19	retrograde	retrograde	JJ
cord-002808-84np9brx	94	20	traffics	traffic	VBZ
cord-002808-84np9brx	94	21	past	past	IN
cord-002808-84np9brx	94	22	the	the	DT
cord-002808-84np9brx	94	23	Golgi	Golgi	NNP
cord-002808-84np9brx	94	24	to	to	IN
cord-002808-84np9brx	94	25	the	the	DT
cord-002808-84np9brx	94	26	ER	ER	NNP
cord-002808-84np9brx	94	27	[	[	-LRB-
cord-002808-84np9brx	94	28	55	55	CD
cord-002808-84np9brx	94	29	]	]	-RRB-
cord-002808-84np9brx	94	30	.	.	.
cord-002808-84np9brx	95	1	Whether	whether	IN
cord-002808-84np9brx	95	2	these	these	DT
cord-002808-84np9brx	95	3	represent	represent	VBP
cord-002808-84np9brx	95	4	primary	primary	JJ
cord-002808-84np9brx	95	5	or	or	CC
cord-002808-84np9brx	95	6	alternative	alternative	JJ
cord-002808-84np9brx	95	7	routes	route	NNS
cord-002808-84np9brx	95	8	of	of	IN
cord-002808-84np9brx	95	9	infection	infection	NN
cord-002808-84np9brx	95	10	,	,	,
cord-002808-84np9brx	95	11	or	or	CC
cord-002808-84np9brx	95	12	even	even	RB
cord-002808-84np9brx	95	13	unproductive	unproductive	JJ
cord-002808-84np9brx	95	14	dead	dead	JJ
cord-002808-84np9brx	95	15	ends	end	NNS
cord-002808-84np9brx	95	16	,	,	,
cord-002808-84np9brx	95	17	is	be	VBZ
cord-002808-84np9brx	95	18	not	not	RB
cord-002808-84np9brx	95	19	clear	clear	JJ
cord-002808-84np9brx	95	20	.	.	.
cord-002808-84np9brx	96	1	It	-PRON-	PRP
cord-002808-84np9brx	96	2	is	be	VBZ
cord-002808-84np9brx	96	3	worth	worth	JJ
cord-002808-84np9brx	96	4	noting	note	VBG
cord-002808-84np9brx	96	5	that	that	IN
cord-002808-84np9brx	96	6	the	the	DT
cord-002808-84np9brx	96	7	dynamic	dynamic	JJ
cord-002808-84np9brx	96	8	flux	flux	NN
cord-002808-84np9brx	96	9	of	of	IN
cord-002808-84np9brx	96	10	proteins	protein	NNS
cord-002808-84np9brx	96	11	within	within	IN
cord-002808-84np9brx	96	12	the	the	DT
cord-002808-84np9brx	96	13	secretory	secretory	JJ
cord-002808-84np9brx	96	14	compartments	compartment	NNS
cord-002808-84np9brx	96	15	makes	make	VBZ
cord-002808-84np9brx	96	16	it	-PRON-	PRP
cord-002808-84np9brx	96	17	difficult	difficult	JJ
cord-002808-84np9brx	96	18	to	to	TO
cord-002808-84np9brx	96	19	precisely	precisely	RB
cord-002808-84np9brx	96	20	determine	determine	VB
cord-002808-84np9brx	96	21	where	where	WRB
cord-002808-84np9brx	96	22	colocalization	colocalization	NN
cord-002808-84np9brx	96	23	is	be	VBZ
cord-002808-84np9brx	96	24	occurring	occur	VBG
cord-002808-84np9brx	96	25	by	by	IN
cord-002808-84np9brx	96	26	microscopy	microscopy	NNS
cord-002808-84np9brx	96	27	.	.	.
cord-002808-84np9brx	97	1	Many	many	JJ
cord-002808-84np9brx	97	2	ER	ER	NNP
cord-002808-84np9brx	97	3	proteins	protein	NNS
cord-002808-84np9brx	97	4	contain	contain	VBP
cord-002808-84np9brx	97	5	a	a	DT
cord-002808-84np9brx	97	6	C	c	NN
cord-002808-84np9brx	97	7	-	-	HYPH
cord-002808-84np9brx	97	8	terminal	terminal	NN
cord-002808-84np9brx	97	9	KDEL	KDEL	NNP
cord-002808-84np9brx	97	10	sequence	sequence	NN
cord-002808-84np9brx	97	11	,	,	,
cord-002808-84np9brx	97	12	and	and	CC
cord-002808-84np9brx	97	13	although	although	IN
cord-002808-84np9brx	97	14	they	-PRON-	PRP
cord-002808-84np9brx	97	15	are	be	VBP
cord-002808-84np9brx	97	16	maintained	maintain	VBN
cord-002808-84np9brx	97	17	within	within	IN
cord-002808-84np9brx	97	18	the	the	DT
cord-002808-84np9brx	97	19	ER	ER	NNP
cord-002808-84np9brx	97	20	at	at	IN
cord-002808-84np9brx	97	21	steady	steady	JJ
cord-002808-84np9brx	97	22	state	state	NN
cord-002808-84np9brx	97	23	,	,	,
cord-002808-84np9brx	97	24	they	-PRON-	PRP
cord-002808-84np9brx	97	25	are	be	VBP
cord-002808-84np9brx	97	26	constantly	constantly	RB
cord-002808-84np9brx	97	27	trafficking	traffic	VBG
cord-002808-84np9brx	97	28	into	into	IN
cord-002808-84np9brx	97	29	the	the	DT
cord-002808-84np9brx	97	30	Golgi	Golgi	NNP
cord-002808-84np9brx	97	31	,	,	,
cord-002808-84np9brx	97	32	where	where	WRB
cord-002808-84np9brx	97	33	they	-PRON-	PRP
cord-002808-84np9brx	97	34	must	must	MD
cord-002808-84np9brx	97	35	be	be	VB
cord-002808-84np9brx	97	36	recycled	recycle	VBN
cord-002808-84np9brx	97	37	back	back	RB
cord-002808-84np9brx	97	38	through	through	IN
cord-002808-84np9brx	97	39	KDEL	KDEL	NNP
cord-002808-84np9brx	97	40	cargo	cargo	NN
cord-002808-84np9brx	97	41	receptor	receptor	NN
cord-002808-84np9brx	97	42	[	[	-LRB-
cord-002808-84np9brx	97	43	56	56	CD
cord-002808-84np9brx	97	44	,	,	,
cord-002808-84np9brx	97	45	57	57	CD
cord-002808-84np9brx	97	46	]	]	-RRB-
cord-002808-84np9brx	97	47	.	.	.
cord-002808-84np9brx	98	1	Sensitive	sensitive	JJ
cord-002808-84np9brx	98	2	techniques	technique	NNS
cord-002808-84np9brx	98	3	like	like	IN
cord-002808-84np9brx	98	4	the	the	DT
cord-002808-84np9brx	98	5	proximity	proximity	NN
cord-002808-84np9brx	98	6	ligation	ligation	NN
cord-002808-84np9brx	98	7	assay	assay	NN
cord-002808-84np9brx	98	8	using	use	VBG
cord-002808-84np9brx	98	9	such	such	JJ
cord-002808-84np9brx	98	10	KDEL	KDEL	NNP
cord-002808-84np9brx	98	11	-	-	HYPH
cord-002808-84np9brx	98	12	containing	contain	VBG
cord-002808-84np9brx	98	13	ER	ER	NNP
cord-002808-84np9brx	98	14	proteins	protein	NNS
cord-002808-84np9brx	98	15	must	must	MD
cord-002808-84np9brx	98	16	therefore	therefore	RB
cord-002808-84np9brx	98	17	be	be	VB
cord-002808-84np9brx	98	18	interpreted	interpret	VBN
cord-002808-84np9brx	98	19	with	with	IN
cord-002808-84np9brx	98	20	caution	caution	NN
cord-002808-84np9brx	98	21	.	.	.
cord-002808-84np9brx	99	1	Since	since	IN
cord-002808-84np9brx	99	2	retrograde	retrograde	JJ
cord-002808-84np9brx	99	3	trafficking	trafficking	NN
cord-002808-84np9brx	99	4	of	of	IN
cord-002808-84np9brx	99	5	L2	l2	NN
cord-002808-84np9brx	99	6	/	/	,
cord-002808-84np9brx	99	7	vDNA	vdna	RB
cord-002808-84np9brx	99	8	to	to	IN
cord-002808-84np9brx	99	9	more	more	RBR
cord-002808-84np9brx	99	10	distal	distal	JJ
cord-002808-84np9brx	99	11	compartments	compartment	NNS
cord-002808-84np9brx	99	12	has	have	VBZ
cord-002808-84np9brx	99	13	not	not	RB
cord-002808-84np9brx	99	14	been	be	VBN
cord-002808-84np9brx	99	15	well	well	RB
cord-002808-84np9brx	99	16	established	establish	VBN
cord-002808-84np9brx	99	17	,	,	,
cord-002808-84np9brx	99	18	this	this	DT
cord-002808-84np9brx	99	19	review	review	NN
cord-002808-84np9brx	99	20	will	will	MD
cord-002808-84np9brx	99	21	simply	simply	RB
cord-002808-84np9brx	99	22	refer	refer	VB
cord-002808-84np9brx	99	23	to	to	IN
cord-002808-84np9brx	99	24	the	the	DT
cord-002808-84np9brx	99	25	final	final	JJ
cord-002808-84np9brx	99	26	retrograde	retrograde	JJ
cord-002808-84np9brx	99	27	destination	destination	NN
cord-002808-84np9brx	99	28	of	of	IN
cord-002808-84np9brx	100	1	L2	L2	NNP
cord-002808-84np9brx	100	2	/	/	,
cord-002808-84np9brx	100	3	vDNA	vdna	XX
cord-002808-84np9brx	100	4	as	as	IN
cord-002808-84np9brx	100	5	the	the	DT
cord-002808-84np9brx	100	6	"	"	``
cord-002808-84np9brx	100	7	TGN	TGN	NNP
cord-002808-84np9brx	100	8	"	"	''
cord-002808-84np9brx	100	9	.	.	.
cord-002808-84np9brx	101	1	The	the	DT
cord-002808-84np9brx	101	2	retromer	retromer	NN
cord-002808-84np9brx	101	3	,	,	,
cord-002808-84np9brx	101	4	a	a	DT
cord-002808-84np9brx	101	5	trimer	trimer	NN
cord-002808-84np9brx	101	6	of	of	IN
cord-002808-84np9brx	101	7	Vps26	Vps26	NNP
cord-002808-84np9brx	101	8	,	,	,
cord-002808-84np9brx	101	9	Vps29	Vps29	NNP
cord-002808-84np9brx	101	10	,	,	,
cord-002808-84np9brx	101	11	and	and	CC
cord-002808-84np9brx	101	12	Vps35	Vps35	NNP
cord-002808-84np9brx	101	13	,	,	,
cord-002808-84np9brx	101	14	is	be	VBZ
cord-002808-84np9brx	101	15	a	a	DT
cord-002808-84np9brx	101	16	cytosolic	cytosolic	JJ
cord-002808-84np9brx	101	17	sorting	sorting	NN
cord-002808-84np9brx	101	18	adaptor	adaptor	NN
cord-002808-84np9brx	101	19	complex	complex	NN
cord-002808-84np9brx	101	20	that	that	WDT
cord-002808-84np9brx	101	21	binds	bind	VBZ
cord-002808-84np9brx	101	22	to	to	IN
cord-002808-84np9brx	101	23	peptide	peptide	NN
cord-002808-84np9brx	101	24	motifs	motif	NNS
cord-002808-84np9brx	101	25	within	within	IN
cord-002808-84np9brx	101	26	the	the	DT
cord-002808-84np9brx	101	27	intracellular	intracellular	JJ
cord-002808-84np9brx	101	28	domains	domain	NNS
cord-002808-84np9brx	101	29	and	and	CC
cord-002808-84np9brx	101	30	cytosolic	cytosolic	JJ
cord-002808-84np9brx	101	31	tails	tail	NNS
cord-002808-84np9brx	101	32	of	of	IN
cord-002808-84np9brx	101	33	membrane	membrane	NN
cord-002808-84np9brx	101	34	-	-	HYPH
cord-002808-84np9brx	101	35	bound	bind	VBN
cord-002808-84np9brx	101	36	receptors	receptor	NNS
cord-002808-84np9brx	101	37	destined	destine	VBN
cord-002808-84np9brx	101	38	for	for	IN
cord-002808-84np9brx	101	39	the	the	DT
cord-002808-84np9brx	101	40	TGN	TGN	NNP
cord-002808-84np9brx	101	41	.	.	.
cord-002808-84np9brx	102	1	Retromer	Retromer	NNP
cord-002808-84np9brx	102	2	works	work	VBZ
cord-002808-84np9brx	102	3	in	in	IN
cord-002808-84np9brx	102	4	concert	concert	NN
cord-002808-84np9brx	102	5	with	with	IN
cord-002808-84np9brx	102	6	molecules	molecule	NNS
cord-002808-84np9brx	102	7	like	like	IN
cord-002808-84np9brx	102	8	Rab7b	Rab7b	NNP
cord-002808-84np9brx	102	9	,	,	,
cord-002808-84np9brx	102	10	Rab9a	Rab9a	NNP
cord-002808-84np9brx	102	11	,	,	,
cord-002808-84np9brx	102	12	and	and	CC
cord-002808-84np9brx	102	13	members	member	NNS
cord-002808-84np9brx	102	14	of	of	IN
cord-002808-84np9brx	102	15	the	the	DT
cord-002808-84np9brx	102	16	sorting	sort	VBG
cord-002808-84np9brx	102	17	nexin	nexin	NN
cord-002808-84np9brx	102	18	family	family	NN
cord-002808-84np9brx	102	19	,	,	,
cord-002808-84np9brx	102	20	including	include	VBG
cord-002808-84np9brx	102	21	SNX3	SNX3	NNP
cord-002808-84np9brx	102	22	,	,	,
cord-002808-84np9brx	102	23	SNX27	SNX27	NNP
cord-002808-84np9brx	102	24	,	,	,
cord-002808-84np9brx	102	25	and	and	CC
cord-002808-84np9brx	102	26	the	the	DT
cord-002808-84np9brx	102	27	BAR	bar	NN
cord-002808-84np9brx	102	28	-	-	HYPH
cord-002808-84np9brx	102	29	domain	domain	NN
cord-002808-84np9brx	102	30	sorting	sort	VBG
cord-002808-84np9brx	102	31	nexins	nexin	NNS
cord-002808-84np9brx	102	32	(	(	-LRB-
cord-002808-84np9brx	102	33	SNX	SNX	NNP
cord-002808-84np9brx	102	34	-	-	HYPH
cord-002808-84np9brx	102	35	BAR	BAR	NNP
cord-002808-84np9brx	102	36	)	)	-RRB-
cord-002808-84np9brx	102	37	,	,	,
cord-002808-84np9brx	102	38	to	to	TO
cord-002808-84np9brx	102	39	sort	sort	VB
cord-002808-84np9brx	102	40	cargos	cargo	NNS
cord-002808-84np9brx	102	41	from	from	IN
cord-002808-84np9brx	102	42	a	a	DT
cord-002808-84np9brx	102	43	variety	variety	NN
cord-002808-84np9brx	102	44	of	of	IN
cord-002808-84np9brx	102	45	endosomal	endosomal	NNP
cord-002808-84np9brx	102	46	compartments	compartment	NNS
cord-002808-84np9brx	102	47	to	to	IN
cord-002808-84np9brx	102	48	the	the	DT
cord-002808-84np9brx	102	49	TGN	TGN	NNP
cord-002808-84np9brx	102	50	[	[	-LRB-
cord-002808-84np9brx	102	51	58	58	CD
cord-002808-84np9brx	102	52	,	,	,
cord-002808-84np9brx	102	53	59	59	CD
cord-002808-84np9brx	102	54	]	]	-RRB-
cord-002808-84np9brx	102	55	.	.	.
cord-002808-84np9brx	103	1	L2	L2	NNP
cord-002808-84np9brx	103	2	contains	contain	VBZ
cord-002808-84np9brx	103	3	conserved	conserved	JJ
cord-002808-84np9brx	103	4	hydrophobic	hydrophobic	JJ
cord-002808-84np9brx	103	5	retromer	retromer	NN
cord-002808-84np9brx	103	6	-	-	HYPH
cord-002808-84np9brx	103	7	binding	bind	VBG
cord-002808-84np9brx	103	8	sites	site	NNS
cord-002808-84np9brx	103	9	near	near	IN
cord-002808-84np9brx	103	10	the	the	DT
cord-002808-84np9brx	103	11	C	C	NNP
cord-002808-84np9brx	103	12	-	-	HYPH
cord-002808-84np9brx	103	13	terminus	terminus	NN
cord-002808-84np9brx	103	14	(	(	-LRB-
cord-002808-84np9brx	103	15	FYL	FYL	NNP
cord-002808-84np9brx	103	16	at	at	IN
cord-002808-84np9brx	103	17	residues	residue	NNS
cord-002808-84np9brx	103	18	446	446	CD
cord-002808-84np9brx	103	19	-	-	SYM
cord-002808-84np9brx	103	20	448	448	CD
cord-002808-84np9brx	103	21	and	and	CC
cord-002808-84np9brx	103	22	YYML	YYML	NNP
cord-002808-84np9brx	103	23	at	at	IN
cord-002808-84np9brx	103	24	residues	residue	NNS
cord-002808-84np9brx	103	25	452	452	CD
cord-002808-84np9brx	103	26	-	-	SYM
cord-002808-84np9brx	103	27	455	455	CD
cord-002808-84np9brx	103	28	for	for	IN
cord-002808-84np9brx	103	29	HPV16	hpv16	NN
cord-002808-84np9brx	103	30	,	,	,
cord-002808-84np9brx	103	31	see	see	VB
cord-002808-84np9brx	103	32	Figure	figure	NN
cord-002808-84np9brx	103	33	1	1	CD
cord-002808-84np9brx	103	34	)	)	-RRB-
cord-002808-84np9brx	103	35	.	.	.
cord-002808-84np9brx	104	1	Mutation	mutation	NN
cord-002808-84np9brx	104	2	of	of	IN
cord-002808-84np9brx	104	3	these	these	DT
cord-002808-84np9brx	104	4	sites	site	NNS
cord-002808-84np9brx	104	5	prevents	prevent	VBZ
cord-002808-84np9brx	104	6	association	association	NNP
cord-002808-84np9brx	104	7	of	of	IN
cord-002808-84np9brx	104	8	L2	L2	NNP
cord-002808-84np9brx	104	9	with	with	IN
cord-002808-84np9brx	104	10	retromer	retromer	NN
cord-002808-84np9brx	104	11	,	,	,
cord-002808-84np9brx	104	12	and	and	CC
cord-002808-84np9brx	104	13	blocks	block	VBZ
cord-002808-84np9brx	104	14	the	the	DT
cord-002808-84np9brx	104	15	trafficking	trafficking	NN
cord-002808-84np9brx	104	16	of	of	IN
cord-002808-84np9brx	104	17	L2	l2	NN
cord-002808-84np9brx	104	18	/	/	,
cord-002808-84np9brx	104	19	vDNA	vdna	NN
cord-002808-84np9brx	104	20	to	to	IN
cord-002808-84np9brx	104	21	the	the	DT
cord-002808-84np9brx	104	22	TGN	TGN	NNP
cord-002808-84np9brx	104	23	,	,	,
cord-002808-84np9brx	104	24	instead	instead	RB
cord-002808-84np9brx	104	25	causing	cause	VBG
cord-002808-84np9brx	104	26	an	an	DT
cord-002808-84np9brx	104	27	accumulation	accumulation	NN
cord-002808-84np9brx	104	28	within	within	IN
cord-002808-84np9brx	104	29	EEA1-positive	EEA1-positive	NNP
cord-002808-84np9brx	104	30	endocytic	endocytic	JJ
cord-002808-84np9brx	104	31	compartments	compartment	NNS
cord-002808-84np9brx	104	32	[	[	-LRB-
cord-002808-84np9brx	104	33	48	48	CD
cord-002808-84np9brx	104	34	]	]	-RRB-
cord-002808-84np9brx	104	35	suggesting	suggest	VBG
cord-002808-84np9brx	104	36	a	a	DT
cord-002808-84np9brx	104	37	retromer	retromer	NN
cord-002808-84np9brx	104	38	-	-	HYPH
cord-002808-84np9brx	104	39	dependent	dependent	JJ
cord-002808-84np9brx	104	40	sorting	sort	VBG
cord-002808-84np9brx	104	41	event	event	NN
cord-002808-84np9brx	104	42	away	away	RB
cord-002808-84np9brx	104	43	from	from	IN
cord-002808-84np9brx	104	44	EE	EE	NNP
cord-002808-84np9brx	104	45	compartments	compartment	NNS
cord-002808-84np9brx	104	46	(	(	-LRB-
cord-002808-84np9brx	104	47	Figure	figure	NN
cord-002808-84np9brx	104	48	2	2	CD
cord-002808-84np9brx	104	49	)	)	-RRB-
cord-002808-84np9brx	104	50	.	.	.
cord-002808-84np9brx	105	1	Likewise	likewise	RB
cord-002808-84np9brx	105	2	,	,	,
cord-002808-84np9brx	105	3	siRNA	siRNA	NNP
cord-002808-84np9brx	105	4	knockdown	knockdown	NN
cord-002808-84np9brx	105	5	of	of	IN
cord-002808-84np9brx	105	6	retromer	retromer	NNP
cord-002808-84np9brx	105	7	components	component	NNS
cord-002808-84np9brx	105	8	also	also	RB
cord-002808-84np9brx	105	9	prevents	prevent	VBZ
cord-002808-84np9brx	105	10	L2	L2	NNP
cord-002808-84np9brx	105	11	/	/	,
cord-002808-84np9brx	105	12	vDNA	vdna	RB
cord-002808-84np9brx	105	13	from	from	IN
cord-002808-84np9brx	105	14	reaching	reach	VBG
cord-002808-84np9brx	105	15	the	the	DT
cord-002808-84np9brx	105	16	TGN	TGN	NNP
cord-002808-84np9brx	105	17	[	[	-LRB-
cord-002808-84np9brx	105	18	48	48	CD
cord-002808-84np9brx	105	19	]	]	-RRB-
cord-002808-84np9brx	105	20	.	.	.
cord-002808-84np9brx	106	1	In	in	IN
cord-002808-84np9brx	106	2	addition	addition	NN
cord-002808-84np9brx	106	3	to	to	IN
cord-002808-84np9brx	106	4	retromer	retromer	NNP
cord-002808-84np9brx	106	5	,	,	,
cord-002808-84np9brx	106	6	L2	L2	NNP
cord-002808-84np9brx	106	7	is	be	VBZ
cord-002808-84np9brx	106	8	capable	capable	JJ
cord-002808-84np9brx	106	9	of	of	IN
cord-002808-84np9brx	106	10	interaction	interaction	NN
cord-002808-84np9brx	106	11	with	with	IN
cord-002808-84np9brx	106	12	SNX17	SNX17	NNP
cord-002808-84np9brx	106	13	and	and	CC
cord-002808-84np9brx	106	14	SNX27	SNX27	NNP
cord-002808-84np9brx	106	15	to	to	TO
cord-002808-84np9brx	106	16	direct	direct	VB
cord-002808-84np9brx	106	17	endosomal	endosomal	NN
cord-002808-84np9brx	106	18	and	and	CC
cord-002808-84np9brx	106	19	retrograde	retrograde	JJ
cord-002808-84np9brx	106	20	trafficking	trafficking	NN
cord-002808-84np9brx	106	21	of	of	IN
cord-002808-84np9brx	106	22	the	the	DT
cord-002808-84np9brx	106	23	vDNA	vdna	JJ
cord-002808-84np9brx	106	24	[	[	-LRB-
cord-002808-84np9brx	106	25	60	60	CD
cord-002808-84np9brx	106	26	,	,	,
cord-002808-84np9brx	106	27	61	61	CD
cord-002808-84np9brx	106	28	]	]	-RRB-
cord-002808-84np9brx	106	29	.	.	.
cord-002808-84np9brx	107	1	The	the	DT
cord-002808-84np9brx	107	2	interaction	interaction	NN
cord-002808-84np9brx	107	3	with	with	IN
cord-002808-84np9brx	107	4	SNX17	SNX17	NNP
cord-002808-84np9brx	107	5	through	through	IN
cord-002808-84np9brx	107	6	a	a	DT
cord-002808-84np9brx	107	7	conserved	conserve	VBN
cord-002808-84np9brx	107	8	motif	motif	NN
cord-002808-84np9brx	107	9	(	(	-LRB-
cord-002808-84np9brx	107	10	NPxY	NPxY	NNP
cord-002808-84np9brx	107	11	,	,	,
cord-002808-84np9brx	107	12	residues	residue	VBZ
cord-002808-84np9brx	107	13	254	254	CD
cord-002808-84np9brx	107	14	-	-	SYM
cord-002808-84np9brx	107	15	257	257	CD
cord-002808-84np9brx	107	16	for	for	IN
cord-002808-84np9brx	107	17	HPV16	hpv16	ADD
cord-002808-84np9brx	107	18	,	,	,
cord-002808-84np9brx	107	19	see	see	VB
cord-002808-84np9brx	107	20	Figure	figure	NN
cord-002808-84np9brx	107	21	1	1	CD
cord-002808-84np9brx	107	22	)	)	-RRB-
cord-002808-84np9brx	107	23	is	be	VBZ
cord-002808-84np9brx	107	24	believed	believe	VBN
cord-002808-84np9brx	107	25	to	to	TO
cord-002808-84np9brx	107	26	occur	occur	VB
cord-002808-84np9brx	107	27	very	very	RB
cord-002808-84np9brx	107	28	early	early	RB
cord-002808-84np9brx	107	29	after	after	IN
cord-002808-84np9brx	107	30	entry	entry	NN
cord-002808-84np9brx	107	31	.	.	.
cord-002808-84np9brx	108	1	One	one	CD
cord-002808-84np9brx	108	2	recent	recent	JJ
cord-002808-84np9brx	108	3	study	study	NN
cord-002808-84np9brx	108	4	observed	observe	VBD
cord-002808-84np9brx	108	5	recruitment	recruitment	NN
cord-002808-84np9brx	108	6	of	of	IN
cord-002808-84np9brx	108	7	SNX17	SNX17	NNP
cord-002808-84np9brx	108	8	to	to	IN
cord-002808-84np9brx	108	9	HPV	hpv	NN
cord-002808-84np9brx	108	10	positive	positive	JJ
cord-002808-84np9brx	108	11	endosomes	endosome	NNS
cord-002808-84np9brx	108	12	by	by	IN
cord-002808-84np9brx	108	13	2	2	CD
cord-002808-84np9brx	108	14	h	h	NN
cord-002808-84np9brx	108	15	post	post	NN
cord-002808-84np9brx	108	16	infection	infection	NN
cord-002808-84np9brx	108	17	,	,	,
cord-002808-84np9brx	108	18	a	a	DT
cord-002808-84np9brx	108	19	phenotype	phenotype	NN
cord-002808-84np9brx	108	20	that	that	WDT
cord-002808-84np9brx	108	21	was	be	VBD
cord-002808-84np9brx	108	22	dependent	dependent	JJ
cord-002808-84np9brx	108	23	on	on	IN
cord-002808-84np9brx	108	24	the	the	DT
cord-002808-84np9brx	108	25	conserved	conserve	VBN
cord-002808-84np9brx	108	26	NPxY	npxy	JJ
cord-002808-84np9brx	108	27	motif	motif	NN
cord-002808-84np9brx	108	28	within	within	IN
cord-002808-84np9brx	108	29	L2	L2	NNP
cord-002808-84np9brx	108	30	[	[	-LRB-
cord-002808-84np9brx	108	31	62	62	CD
cord-002808-84np9brx	108	32	]	]	-RRB-
cord-002808-84np9brx	108	33	.	.	.
cord-002808-84np9brx	109	1	The	the	DT
cord-002808-84np9brx	109	2	SNX17-L2	SNX17-L2	NNP
cord-002808-84np9brx	109	3	interaction	interaction	NN
cord-002808-84np9brx	109	4	likely	likely	RB
cord-002808-84np9brx	109	5	promotes	promote	VBZ
cord-002808-84np9brx	109	6	retention	retention	NN
cord-002808-84np9brx	109	7	/	/	SYM
cord-002808-84np9brx	109	8	recycling	recycling	NN
cord-002808-84np9brx	109	9	Viruses	virus	NNS
cord-002808-84np9brx	109	10	2017	2017	CD
cord-002808-84np9brx	109	11	,	,	,
cord-002808-84np9brx	109	12	9	9	CD
cord-002808-84np9brx	109	13	,	,	,
cord-002808-84np9brx	109	14	370	370	CD
cord-002808-84np9brx	109	15	5	5	CD
cord-002808-84np9brx	109	16	of	of	IN
cord-002808-84np9brx	109	17	18	18	CD
cord-002808-84np9brx	109	18	of	of	IN
cord-002808-84np9brx	109	19	the	the	DT
cord-002808-84np9brx	109	20	L2	L2	NNP
cord-002808-84np9brx	109	21	/	/	,
cord-002808-84np9brx	109	22	vDNA	vdna	RB
cord-002808-84np9brx	109	23	complex	complex	NN
cord-002808-84np9brx	109	24	within	within	IN
cord-002808-84np9brx	109	25	the	the	DT
cord-002808-84np9brx	109	26	endosomal	endosomal	NNP
cord-002808-84np9brx	109	27	compartment	compartment	NN
cord-002808-84np9brx	109	28	,	,	,
cord-002808-84np9brx	109	29	preventing	prevent	VBG
cord-002808-84np9brx	109	30	the	the	DT
cord-002808-84np9brx	109	31	rapid	rapid	JJ
cord-002808-84np9brx	109	32	trafficking	trafficking	NN
cord-002808-84np9brx	109	33	and	and	CC
cord-002808-84np9brx	109	34	degradation	degradation	NN
cord-002808-84np9brx	109	35	of	of	IN
cord-002808-84np9brx	109	36	L2	l2	NN
cord-002808-84np9brx	109	37	/	/	,
cord-002808-84np9brx	109	38	vDNA	vdna	RB
cord-002808-84np9brx	109	39	within	within	IN
cord-002808-84np9brx	109	40	lysosomal	lysosomal	JJ
cord-002808-84np9brx	109	41	compartments	compartment	NNS
cord-002808-84np9brx	109	42	[	[	-LRB-
cord-002808-84np9brx	109	43	60	60	CD
cord-002808-84np9brx	109	44	]	]	-RRB-
cord-002808-84np9brx	109	45	.	.	.
cord-002808-84np9brx	110	1	Perhaps	perhaps	RB
cord-002808-84np9brx	110	2	the	the	DT
cord-002808-84np9brx	110	3	virion	virion	NN
cord-002808-84np9brx	110	4	requires	require	VBZ
cord-002808-84np9brx	110	5	a	a	DT
cord-002808-84np9brx	110	6	relatively	relatively	RB
cord-002808-84np9brx	110	7	long	long	JJ
cord-002808-84np9brx	110	8	retention	retention	NN
cord-002808-84np9brx	110	9	time	time	NN
cord-002808-84np9brx	110	10	in	in	IN
cord-002808-84np9brx	110	11	moderately	moderately	RB
cord-002808-84np9brx	110	12	acidic	acidic	JJ
cord-002808-84np9brx	110	13	EE	ee	NN
cord-002808-84np9brx	110	14	and	and	CC
cord-002808-84np9brx	110	15	LE	LE	NNP
cord-002808-84np9brx	110	16	/	/	SYM
cord-002808-84np9brx	110	17	MVB	MVB	NNP
cord-002808-84np9brx	110	18	environments	environment	NNS
cord-002808-84np9brx	110	19	for	for	IN
cord-002808-84np9brx	110	20	efficient	efficient	JJ
cord-002808-84np9brx	110	21	uncoating	uncoating	NN
cord-002808-84np9brx	110	22	,	,	,
cord-002808-84np9brx	110	23	partitioning	partitioning	NN
cord-002808-84np9brx	110	24	of	of	IN
cord-002808-84np9brx	110	25	the	the	DT
cord-002808-84np9brx	110	26	L2	L2	NNP
cord-002808-84np9brx	110	27	/	/	SYM
cord-002808-84np9brx	110	28	vDNA	vdna	RB
cord-002808-84np9brx	110	29	subviral	subviral	JJ
cord-002808-84np9brx	110	30	complex	complex	NN
cord-002808-84np9brx	110	31	from	from	IN
cord-002808-84np9brx	110	32	L1	L1	NNP
cord-002808-84np9brx	110	33	,	,	,
cord-002808-84np9brx	110	34	and/or	and/or	CC
cord-002808-84np9brx	110	35	recruitment	recruitment	NN
cord-002808-84np9brx	110	36	of	of	IN
cord-002808-84np9brx	110	37	the	the	DT
cord-002808-84np9brx	110	38	retromer	retromer	NN
cord-002808-84np9brx	110	39	?	?	.
cord-002808-84np9brx	111	1	Mutation	mutation	NN
cord-002808-84np9brx	111	2	of	of	IN
cord-002808-84np9brx	111	3	the	the	DT
cord-002808-84np9brx	111	4	NPxY	npxy	JJ
cord-002808-84np9brx	111	5	motif	motif	NN
cord-002808-84np9brx	111	6	or	or	CC
cord-002808-84np9brx	111	7	knockdown	knockdown	NN
cord-002808-84np9brx	111	8	of	of	IN
cord-002808-84np9brx	111	9	SNX17	SNX17	NNP
cord-002808-84np9brx	111	10	results	result	NNS
cord-002808-84np9brx	111	11	in	in	IN
cord-002808-84np9brx	111	12	aberrant	aberrant	JJ
cord-002808-84np9brx	111	13	L2	l2	NN
cord-002808-84np9brx	111	14	/	/	,
cord-002808-84np9brx	111	15	vDNA	vdna	NN
cord-002808-84np9brx	111	16	trafficking	trafficking	NN
cord-002808-84np9brx	111	17	and	and	CC
cord-002808-84np9brx	111	18	decreased	decrease	VBD
cord-002808-84np9brx	111	19	infectivity	infectivity	NN
cord-002808-84np9brx	111	20	[	[	-LRB-
cord-002808-84np9brx	111	21	60	60	CD
cord-002808-84np9brx	111	22	]	]	-RRB-
cord-002808-84np9brx	111	23	.	.	.
cord-002808-84np9brx	112	1	SNX17	SNX17	NNP
cord-002808-84np9brx	112	2	uses	use	VBZ
cord-002808-84np9brx	112	3	its	-PRON-	PRP$
cord-002808-84np9brx	112	4	FERM	FERM	NNP
cord-002808-84np9brx	112	5	domain	domain	NN
cord-002808-84np9brx	112	6	to	to	TO
cord-002808-84np9brx	112	7	bind	bind	VB
cord-002808-84np9brx	112	8	to	to	IN
cord-002808-84np9brx	112	9	cargo	cargo	NN
cord-002808-84np9brx	112	10	harboring	harbor	VBG
cord-002808-84np9brx	112	11	the	the	DT
cord-002808-84np9brx	112	12	NPxY	npxy	JJ
cord-002808-84np9brx	112	13	motif	motif	NN
cord-002808-84np9brx	112	14	.	.	.
cord-002808-84np9brx	113	1	SNX27	SNX27	NNP
cord-002808-84np9brx	113	2	is	be	VBZ
cord-002808-84np9brx	113	3	another	another	DT
cord-002808-84np9brx	113	4	FERM	FERM	NNP
cord-002808-84np9brx	113	5	domain	domain	NN
cord-002808-84np9brx	113	6	-	-	HYPH
cord-002808-84np9brx	113	7	containing	contain	VBG
cord-002808-84np9brx	113	8	SNX	SNX	NNP
cord-002808-84np9brx	113	9	involved	involve	VBN
cord-002808-84np9brx	113	10	in	in	IN
cord-002808-84np9brx	113	11	L2	L2	NNP
cord-002808-84np9brx	113	12	/	/	,
cord-002808-84np9brx	113	13	vDNA	vdna	NN
cord-002808-84np9brx	113	14	trafficking	trafficking	NN
cord-002808-84np9brx	113	15	but	but	CC
cord-002808-84np9brx	113	16	,	,	,
cord-002808-84np9brx	113	17	unlike	unlike	IN
cord-002808-84np9brx	113	18	SNX17	SNX17	NNP
cord-002808-84np9brx	113	19	,	,	,
cord-002808-84np9brx	113	20	SNX27	SNX27	NNP
cord-002808-84np9brx	113	21	does	do	VBZ
cord-002808-84np9brx	113	22	not	not	RB
cord-002808-84np9brx	113	23	interact	interact	VB
cord-002808-84np9brx	113	24	with	with	IN
cord-002808-84np9brx	113	25	L2	L2	NNP
cord-002808-84np9brx	113	26	through	through	IN
cord-002808-84np9brx	113	27	the	the	DT
cord-002808-84np9brx	113	28	conserved	conserve	VBN
cord-002808-84np9brx	113	29	NPxY	npxy	JJ
cord-002808-84np9brx	113	30	motif	motif	NN
cord-002808-84np9brx	113	31	.	.	.
cord-002808-84np9brx	114	1	In	in	IN
cord-002808-84np9brx	114	2	addition	addition	NN
cord-002808-84np9brx	114	3	to	to	IN
cord-002808-84np9brx	114	4	a	a	DT
cord-002808-84np9brx	114	5	FERM	FERM	NNP
cord-002808-84np9brx	114	6	domain	domain	NN
cord-002808-84np9brx	114	7	,	,	,
cord-002808-84np9brx	114	8	SNX27	SNX27	NNP
cord-002808-84np9brx	114	9	also	also	RB
cord-002808-84np9brx	114	10	contains	contain	VBZ
cord-002808-84np9brx	114	11	a	a	DT
cord-002808-84np9brx	114	12	PDZ	PDZ	NNP
cord-002808-84np9brx	114	13	domain	domain	NN
cord-002808-84np9brx	114	14	,	,	,
cord-002808-84np9brx	114	15	which	which	WDT
cord-002808-84np9brx	114	16	mediates	mediate	VBZ
cord-002808-84np9brx	114	17	interaction	interaction	NN
cord-002808-84np9brx	114	18	with	with	IN
cord-002808-84np9brx	114	19	L2	L2	NNP
cord-002808-84np9brx	114	20	through	through	IN
cord-002808-84np9brx	114	21	a	a	DT
cord-002808-84np9brx	114	22	non	non	JJ
cord-002808-84np9brx	114	23	-	-	JJ
cord-002808-84np9brx	114	24	canonical	canonical	JJ
cord-002808-84np9brx	114	25	PDZ	PDZ	NNP
cord-002808-84np9brx	114	26	ligand	ligand	NN
cord-002808-84np9brx	114	27	located	locate	VBN
cord-002808-84np9brx	114	28	somewhere	somewhere	RB
cord-002808-84np9brx	114	29	in	in	IN
cord-002808-84np9brx	114	30	between	between	IN
cord-002808-84np9brx	114	31	residues	residue	NNS
cord-002808-84np9brx	114	32	192	192	CD
cord-002808-84np9brx	114	33	-	-	SYM
cord-002808-84np9brx	114	34	292	292	CD
cord-002808-84np9brx	114	35	of	of	IN
cord-002808-84np9brx	114	36	HPV16	hpv16	NN
cord-002808-84np9brx	114	37	L2	L2	NNP
cord-002808-84np9brx	114	38	[	[	-LRB-
cord-002808-84np9brx	114	39	61	61	CD
cord-002808-84np9brx	114	40	]	]	-RRB-
cord-002808-84np9brx	114	41	.	.	.
cord-002808-84np9brx	115	1	Notably	notably	RB
cord-002808-84np9brx	115	2	,	,	,
cord-002808-84np9brx	115	3	both	both	CC
cord-002808-84np9brx	115	4	SNX17	SNX17	NNP
cord-002808-84np9brx	115	5	and	and	CC
cord-002808-84np9brx	115	6	SNX27	SNX27	NNP
cord-002808-84np9brx	115	7	have	have	VBP
cord-002808-84np9brx	115	8	been	be	VBN
cord-002808-84np9brx	115	9	implicated	implicate	VBN
cord-002808-84np9brx	115	10	in	in	IN
cord-002808-84np9brx	115	11	efficient	efficient	JJ
cord-002808-84np9brx	115	12	retrograde	retrograde	JJ
cord-002808-84np9brx	115	13	trafficking	trafficking	NN
cord-002808-84np9brx	115	14	through	through	IN
cord-002808-84np9brx	115	15	the	the	DT
cord-002808-84np9brx	115	16	retromer	retromer	NN
cord-002808-84np9brx	115	17	[	[	-LRB-
cord-002808-84np9brx	115	18	59	59	CD
cord-002808-84np9brx	115	19	,	,	,
cord-002808-84np9brx	115	20	63	63	CD
cord-002808-84np9brx	115	21	]	]	-RRB-
cord-002808-84np9brx	115	22	,	,	,
cord-002808-84np9brx	115	23	raising	raise	VBG
cord-002808-84np9brx	115	24	the	the	DT
cord-002808-84np9brx	115	25	possibility	possibility	NN
cord-002808-84np9brx	115	26	that	that	IN
cord-002808-84np9brx	115	27	cooperative	cooperative	JJ
cord-002808-84np9brx	115	28	interactions	interaction	NNS
cord-002808-84np9brx	115	29	of	of	IN
cord-002808-84np9brx	115	30	L2	l2	NN
cord-002808-84np9brx	115	31	with	with	IN
cord-002808-84np9brx	115	32	these	these	DT
cord-002808-84np9brx	115	33	SNXs	snx	NNS
cord-002808-84np9brx	115	34	may	may	MD
cord-002808-84np9brx	115	35	somehow	somehow	RB
cord-002808-84np9brx	115	36	promote	promote	VB
cord-002808-84np9brx	115	37	retromer	retromer	NN
cord-002808-84np9brx	115	38	-	-	HYPH
cord-002808-84np9brx	115	39	dependent	dependent	JJ
cord-002808-84np9brx	115	40	TGN	TGN	NNP
cord-002808-84np9brx	115	41	localization	localization	NN
cord-002808-84np9brx	115	42	.	.	.
cord-002808-84np9brx	116	1	Recent	recent	JJ
cord-002808-84np9brx	116	2	work	work	NN
cord-002808-84np9brx	116	3	has	have	VBZ
cord-002808-84np9brx	116	4	revealed	reveal	VBN
cord-002808-84np9brx	116	5	the	the	DT
cord-002808-84np9brx	116	6	existence	existence	NN
cord-002808-84np9brx	116	7	of	of	IN
cord-002808-84np9brx	116	8	an	an	DT
cord-002808-84np9brx	116	9	additional	additional	JJ
cord-002808-84np9brx	116	10	trimeric	trimeric	JJ
cord-002808-84np9brx	116	11	sorting	sorting	NN
cord-002808-84np9brx	116	12	complex	complex	NN
cord-002808-84np9brx	116	13	called	call	VBN
cord-002808-84np9brx	116	14	the	the	DT
cord-002808-84np9brx	116	15	retriever	retriever	NN
cord-002808-84np9brx	116	16	,	,	,
cord-002808-84np9brx	116	17	which	which	WDT
cord-002808-84np9brx	116	18	functions	function	VBZ
cord-002808-84np9brx	116	19	in	in	IN
cord-002808-84np9brx	116	20	concert	concert	NN
cord-002808-84np9brx	116	21	with	with	IN
cord-002808-84np9brx	116	22	SNX17	SNX17	NNP
cord-002808-84np9brx	116	23	,	,	,
cord-002808-84np9brx	116	24	the	the	DT
cord-002808-84np9brx	116	25	CCC	CCC	NNP
cord-002808-84np9brx	116	26	,	,	,
cord-002808-84np9brx	116	27	and	and	CC
cord-002808-84np9brx	116	28	WASH	wash	VB
cord-002808-84np9brx	116	29	complexes	complex	NNS
cord-002808-84np9brx	116	30	to	to	TO
cord-002808-84np9brx	116	31	sort	sort	VB
cord-002808-84np9brx	116	32	cargo	cargo	NN
cord-002808-84np9brx	116	33	from	from	IN
cord-002808-84np9brx	116	34	degradative	degradative	NNP
cord-002808-84np9brx	116	35	to	to	IN
cord-002808-84np9brx	116	36	recycling	recycling	NN
cord-002808-84np9brx	116	37	compartments	compartment	NNS
cord-002808-84np9brx	116	38	.	.	.
cord-002808-84np9brx	117	1	Retriever	Retriever	NNP
cord-002808-84np9brx	117	2	consists	consist	VBZ
cord-002808-84np9brx	117	3	of	of	IN
cord-002808-84np9brx	117	4	three	three	CD
cord-002808-84np9brx	117	5	subunits	subunit	NNS
cord-002808-84np9brx	117	6	-	-	,
cord-002808-84np9brx	117	7	DSCR3	dscr3	ADD
cord-002808-84np9brx	117	8	,	,	,
cord-002808-84np9brx	117	9	C16orf62	C16orf62	NNP
cord-002808-84np9brx	117	10	,	,	,
cord-002808-84np9brx	117	11	and	and	CC
cord-002808-84np9brx	117	12	Vps29	Vps29	NNP
cord-002808-84np9brx	117	13	,	,	,
cord-002808-84np9brx	117	14	a	a	DT
cord-002808-84np9brx	117	15	subunit	subunit	NN
cord-002808-84np9brx	117	16	in	in	IN
cord-002808-84np9brx	117	17	common	common	JJ
cord-002808-84np9brx	117	18	with	with	IN
cord-002808-84np9brx	117	19	the	the	DT
cord-002808-84np9brx	117	20	retromer	retromer	NN
cord-002808-84np9brx	117	21	[	[	-LRB-
cord-002808-84np9brx	117	22	64	64	CD
cord-002808-84np9brx	117	23	]	]	-RRB-
cord-002808-84np9brx	117	24	.	.	.
cord-002808-84np9brx	118	1	HPV	hpv	NN
cord-002808-84np9brx	118	2	infection	infection	NN
cord-002808-84np9brx	118	3	is	be	VBZ
cord-002808-84np9brx	118	4	decreased	decrease	VBN
cord-002808-84np9brx	118	5	upon	upon	IN
cord-002808-84np9brx	118	6	knockdown	knockdown	NN
cord-002808-84np9brx	118	7	of	of	IN
cord-002808-84np9brx	118	8	retriever	retriever	NN
cord-002808-84np9brx	118	9	components	component	NNS
cord-002808-84np9brx	118	10	DSCR3	dscr3	NN
cord-002808-84np9brx	118	11	and	and	CC
cord-002808-84np9brx	118	12	C16orf62	C16orf62	NNP
cord-002808-84np9brx	118	13	,	,	,
cord-002808-84np9brx	118	14	as	as	RB
cord-002808-84np9brx	118	15	well	well	RB
cord-002808-84np9brx	118	16	as	as	IN
cord-002808-84np9brx	118	17	CCC	CCC	NNP
cord-002808-84np9brx	118	18	components	component	NNS
cord-002808-84np9brx	118	19	CCDC	CCDC	NNP
cord-002808-84np9brx	118	20	22	22	CD
cord-002808-84np9brx	119	1	and	and	CC
cord-002808-84np9brx	119	2	CCDC93	CCDC93	NNP
cord-002808-84np9brx	119	3	,	,	,
cord-002808-84np9brx	119	4	suggesting	suggest	VBG
cord-002808-84np9brx	119	5	a	a	DT
cord-002808-84np9brx	119	6	role	role	NN
cord-002808-84np9brx	119	7	for	for	IN
cord-002808-84np9brx	119	8	this	this	DT
cord-002808-84np9brx	119	9	novel	novel	JJ
cord-002808-84np9brx	119	10	pathway	pathway	NN
cord-002808-84np9brx	119	11	in	in	IN
cord-002808-84np9brx	119	12	HPV	HPV	NNP
cord-002808-84np9brx	119	13	infection	infection	NN
cord-002808-84np9brx	119	14	[	[	-LRB-
cord-002808-84np9brx	119	15	64	64	CD
cord-002808-84np9brx	119	16	]	]	-RRB-
cord-002808-84np9brx	119	17	.	.	.
cord-002808-84np9brx	120	1	ESCRT	ESCRT	NNP
cord-002808-84np9brx	120	2	proteins	protein	NNS
cord-002808-84np9brx	120	3	,	,	,
cord-002808-84np9brx	120	4	tetraspanins	tetraspanin	NNS
cord-002808-84np9brx	120	5	,	,	,
cord-002808-84np9brx	120	6	SNXs	snx	NNS
cord-002808-84np9brx	120	7	,	,	,
cord-002808-84np9brx	120	8	and	and	CC
cord-002808-84np9brx	120	9	retromer	retromer	VB
cord-002808-84np9brx	120	10	all	all	DT
cord-002808-84np9brx	120	11	have	have	VBP
cord-002808-84np9brx	120	12	physiological	physiological	JJ
cord-002808-84np9brx	120	13	roles	role	NNS
cord-002808-84np9brx	120	14	in	in	IN
cord-002808-84np9brx	120	15	subcellular	subcellular	JJ
cord-002808-84np9brx	120	16	trafficking	trafficking	NN
cord-002808-84np9brx	120	17	and	and	CC
cord-002808-84np9brx	120	18	protein	protein	NN
cord-002808-84np9brx	120	19	transport	transport	NN
cord-002808-84np9brx	120	20	,	,	,
cord-002808-84np9brx	120	21	and	and	CC
cord-002808-84np9brx	120	22	thus	thus	RB
cord-002808-84np9brx	120	23	many	many	JJ
cord-002808-84np9brx	120	24	of	of	IN
cord-002808-84np9brx	120	25	these	these	DT
cord-002808-84np9brx	120	26	natural	natural	JJ
cord-002808-84np9brx	120	27	pathways	pathway	NNS
cord-002808-84np9brx	120	28	and	and	CC
cord-002808-84np9brx	120	29	components	component	NNS
cord-002808-84np9brx	120	30	are	be	VBP
cord-002808-84np9brx	120	31	exploited	exploit	VBN
cord-002808-84np9brx	120	32	and	and	CC
cord-002808-84np9brx	120	33	commandeered	commandeer	VBN
cord-002808-84np9brx	120	34	by	by	IN
cord-002808-84np9brx	120	35	different	different	JJ
cord-002808-84np9brx	120	36	viruses	virus	NNS
cord-002808-84np9brx	120	37	for	for	IN
cord-002808-84np9brx	120	38	entry	entry	NN
cord-002808-84np9brx	120	39	or	or	CC
cord-002808-84np9brx	120	40	assembly	assembly	NN
cord-002808-84np9brx	120	41	.	.	.
cord-002808-84np9brx	121	1	Perhaps	perhaps	RB
cord-002808-84np9brx	121	2	the	the	DT
cord-002808-84np9brx	121	3	most	most	RBS
cord-002808-84np9brx	121	4	mysterious	mysterious	JJ
cord-002808-84np9brx	121	5	host	host	NN
cord-002808-84np9brx	121	6	factor	factor	NN
cord-002808-84np9brx	121	7	necessary	necessary	JJ
cord-002808-84np9brx	121	8	for	for	IN
cord-002808-84np9brx	121	9	HPV	hpv	NN
cord-002808-84np9brx	121	10	infection	infection	NN
cord-002808-84np9brx	121	11	is	be	VBZ
cord-002808-84np9brx	121	12	the	the	DT
cord-002808-84np9brx	121	13	multisubunit	multisubunit	NNP
cord-002808-84np9brx	121	14	intramembrane	intramembrane	NNP
cord-002808-84np9brx	121	15	protease	protease	NNP
cord-002808-84np9brx	121	16	γ	γ	NNP
cord-002808-84np9brx	121	17	-	-	HYPH
cord-002808-84np9brx	121	18	secretase	secretase	NNP
cord-002808-84np9brx	121	19	(	(	-LRB-
cord-002808-84np9brx	121	20	γ	γ	NNP
cord-002808-84np9brx	121	21	-	-	HYPH
cord-002808-84np9brx	121	22	sec	sec	NNP
cord-002808-84np9brx	121	23	)	)	-RRB-
cord-002808-84np9brx	121	24	,	,	,
cord-002808-84np9brx	121	25	which	which	WDT
cord-002808-84np9brx	121	26	appears	appear	VBZ
cord-002808-84np9brx	121	27	to	to	TO
cord-002808-84np9brx	121	28	be	be	VB
cord-002808-84np9brx	121	29	a	a	DT
cord-002808-84np9brx	121	30	unique	unique	JJ
cord-002808-84np9brx	121	31	requirement	requirement	NN
cord-002808-84np9brx	121	32	of	of	IN
cord-002808-84np9brx	121	33	papillomaviruses	papillomaviruse	NNS
cord-002808-84np9brx	121	34	.	.	.
cord-002808-84np9brx	122	1	The	the	DT
cord-002808-84np9brx	122	2	γ	γ	NN
cord-002808-84np9brx	122	3	-	-	HYPH
cord-002808-84np9brx	122	4	sec	sec	NNP
cord-002808-84np9brx	122	5	complex	complex	NN
cord-002808-84np9brx	122	6	is	be	VBZ
cord-002808-84np9brx	122	7	a	a	DT
cord-002808-84np9brx	122	8	transmembrane	transmembrane	NN
cord-002808-84np9brx	122	9	protease	protease	NN
cord-002808-84np9brx	122	10	comprised	comprise	VBN
cord-002808-84np9brx	122	11	of	of	IN
cord-002808-84np9brx	122	12	four	four	CD
cord-002808-84np9brx	122	13	subunits	subunit	NNS
cord-002808-84np9brx	122	14	:	:	:
cord-002808-84np9brx	122	15	presenilin1/2	presenilin1/2	ADD
cord-002808-84np9brx	122	16	(	(	-LRB-
cord-002808-84np9brx	122	17	PS1/2	PS1/2	NNP
cord-002808-84np9brx	122	18	)	)	-RRB-
cord-002808-84np9brx	122	19	,	,	,
cord-002808-84np9brx	122	20	nicastrin	nicastrin	NNP
cord-002808-84np9brx	122	21	(	(	-LRB-
cord-002808-84np9brx	122	22	Nic	Nic	NNP
cord-002808-84np9brx	122	23	)	)	-RRB-
cord-002808-84np9brx	122	24	,	,	,
cord-002808-84np9brx	122	25	Aph1a	Aph1a	NNP
cord-002808-84np9brx	122	26	/	/	SYM
cord-002808-84np9brx	122	27	b	b	NN
cord-002808-84np9brx	122	28	,	,	,
cord-002808-84np9brx	122	29	and	and	CC
cord-002808-84np9brx	122	30	PEN2	PEN2	NNP
cord-002808-84np9brx	122	31	.	.	.
cord-002808-84np9brx	123	1	Two	two	CD
cord-002808-84np9brx	123	2	isoforms	isoform	NNS
cord-002808-84np9brx	123	3	exist	exist	VBP
cord-002808-84np9brx	123	4	for	for	IN
cord-002808-84np9brx	123	5	both	both	CC
cord-002808-84np9brx	123	6	PS	PS	NNP
cord-002808-84np9brx	123	7	and	and	CC
cord-002808-84np9brx	123	8	Aph1	Aph1	NNP
cord-002808-84np9brx	123	9	,	,	,
cord-002808-84np9brx	123	10	so	so	CC
cord-002808-84np9brx	123	11	there	there	EX
cord-002808-84np9brx	123	12	is	be	VBZ
cord-002808-84np9brx	123	13	heterogeneity	heterogeneity	NN
cord-002808-84np9brx	123	14	among	among	IN
cord-002808-84np9brx	123	15	cellular	cellular	JJ
cord-002808-84np9brx	123	16	γ	γ	NN
cord-002808-84np9brx	123	17	-	-	HYPH
cord-002808-84np9brx	123	18	sec	sec	NNP
cord-002808-84np9brx	123	19	complexes	complex	NNS
cord-002808-84np9brx	123	20	[	[	-LRB-
cord-002808-84np9brx	123	21	65	65	CD
cord-002808-84np9brx	123	22	]	]	-RRB-
cord-002808-84np9brx	123	23	.	.	.
cord-002808-84np9brx	124	1	γ	γ	NNP
cord-002808-84np9brx	124	2	-	-	HYPH
cord-002808-84np9brx	124	3	sec	sec	NNP
cord-002808-84np9brx	124	4	catalyzes	catalyze	VBZ
cord-002808-84np9brx	124	5	the	the	DT
cord-002808-84np9brx	124	6	intramembrane	intramembrane	NNP
cord-002808-84np9brx	124	7	cleavage	cleavage	NN
cord-002808-84np9brx	124	8	of	of	IN
cord-002808-84np9brx	124	9	TMDs	tmd	NNS
cord-002808-84np9brx	124	10	from	from	IN
cord-002808-84np9brx	124	11	a	a	DT
cord-002808-84np9brx	124	12	wide	wide	JJ
cord-002808-84np9brx	124	13	variety	variety	NN
cord-002808-84np9brx	124	14	of	of	IN
cord-002808-84np9brx	124	15	membrane	membrane	NN
cord-002808-84np9brx	124	16	proteins	protein	NNS
cord-002808-84np9brx	124	17	[	[	-LRB-
cord-002808-84np9brx	124	18	66	66	CD
cord-002808-84np9brx	124	19	]	]	-RRB-
cord-002808-84np9brx	124	20	,	,	,
cord-002808-84np9brx	124	21	and	and	CC
cord-002808-84np9brx	124	22	is	be	VBZ
cord-002808-84np9brx	124	23	perhaps	perhaps	RB
cord-002808-84np9brx	124	24	best	well	RBS
cord-002808-84np9brx	124	25	known	know	VBN
cord-002808-84np9brx	124	26	as	as	IN
cord-002808-84np9brx	124	27	an	an	DT
cord-002808-84np9brx	124	28	important	important	JJ
cord-002808-84np9brx	124	29	component	component	NN
cord-002808-84np9brx	124	30	of	of	IN
cord-002808-84np9brx	124	31	the	the	DT
cord-002808-84np9brx	124	32	Notch	notch	NN
cord-002808-84np9brx	124	33	signaling	signal	VBG
cord-002808-84np9brx	124	34	pathway	pathway	NN
cord-002808-84np9brx	124	35	and	and	CC
cord-002808-84np9brx	124	36	the	the	DT
cord-002808-84np9brx	124	37	biogenesis	biogenesis	NN
cord-002808-84np9brx	124	38	of	of	IN
cord-002808-84np9brx	124	39	Aβ	Aβ	NNP
cord-002808-84np9brx	124	40	peptides	peptide	NNS
cord-002808-84np9brx	124	41	from	from	IN
cord-002808-84np9brx	124	42	amyloid	amyloid	NN
cord-002808-84np9brx	124	43	precursor	precursor	NN
cord-002808-84np9brx	124	44	protein	protein	NN
cord-002808-84np9brx	124	45	(	(	-LRB-
cord-002808-84np9brx	124	46	APP	app	NN
cord-002808-84np9brx	124	47	)	)	-RRB-
cord-002808-84np9brx	125	1	[	[	-LRB-
cord-002808-84np9brx	125	2	67	67	CD
cord-002808-84np9brx	125	3	]	]	-RRB-
cord-002808-84np9brx	126	1	[	[	-LRB-
cord-002808-84np9brx	126	2	68	68	CD
cord-002808-84np9brx	126	3	]	]	-RRB-
cord-002808-84np9brx	126	4	[	[	-LRB-
cord-002808-84np9brx	126	5	69	69	CD
cord-002808-84np9brx	126	6	]	]	-RRB-
cord-002808-84np9brx	126	7	[	[	-LRB-
cord-002808-84np9brx	126	8	70	70	CD
cord-002808-84np9brx	126	9	]	]	-RRB-
cord-002808-84np9brx	126	10	.	.	.
cord-002808-84np9brx	127	1	Biochemical	biochemical	JJ
cord-002808-84np9brx	127	2	inhibition	inhibition	NN
cord-002808-84np9brx	127	3	of	of	IN
cord-002808-84np9brx	127	4	γ	γ	NNP
cord-002808-84np9brx	127	5	-	-	HYPH
cord-002808-84np9brx	127	6	sec	sec	NNP
cord-002808-84np9brx	127	7	or	or	CC
cord-002808-84np9brx	127	8	knockdown	knockdown	NN
cord-002808-84np9brx	127	9	of	of	IN
cord-002808-84np9brx	127	10	any	any	DT
cord-002808-84np9brx	127	11	of	of	IN
cord-002808-84np9brx	127	12	the	the	DT
cord-002808-84np9brx	127	13	four	four	CD
cord-002808-84np9brx	127	14	subunits	subunit	NNS
cord-002808-84np9brx	127	15	results	result	NNS
cord-002808-84np9brx	127	16	in	in	IN
cord-002808-84np9brx	127	17	a	a	DT
cord-002808-84np9brx	127	18	potent	potent	JJ
cord-002808-84np9brx	127	19	block	block	NN
cord-002808-84np9brx	127	20	of	of	IN
cord-002808-84np9brx	127	21	HPV	hpv	NN
cord-002808-84np9brx	127	22	infection	infection	NN
cord-002808-84np9brx	127	23	[	[	-LRB-
cord-002808-84np9brx	127	24	55	55	CD
cord-002808-84np9brx	127	25	,	,	,
cord-002808-84np9brx	127	26	71	71	CD
cord-002808-84np9brx	127	27	]	]	-RRB-
cord-002808-84np9brx	127	28	.	.	.
cord-002808-84np9brx	128	1	In	in	IN
cord-002808-84np9brx	128	2	a	a	DT
cord-002808-84np9brx	128	3	screen	screen	NN
cord-002808-84np9brx	128	4	of	of	IN
cord-002808-84np9brx	128	5	a	a	DT
cord-002808-84np9brx	128	6	diverse	diverse	JJ
cord-002808-84np9brx	128	7	panel	panel	NN
cord-002808-84np9brx	128	8	of	of	IN
cord-002808-84np9brx	128	9	34	34	CD
cord-002808-84np9brx	128	10	different	different	JJ
cord-002808-84np9brx	128	11	mucosal	mucosal	JJ
cord-002808-84np9brx	128	12	and	and	CC
cord-002808-84np9brx	128	13	cutaneous	cutaneous	JJ
cord-002808-84np9brx	128	14	HPV	hpv	NN
cord-002808-84np9brx	128	15	types	type	NNS
cord-002808-84np9brx	128	16	,	,	,
cord-002808-84np9brx	128	17	sensitivity	sensitivity	NN
cord-002808-84np9brx	128	18	to	to	IN
cord-002808-84np9brx	128	19	γ	γ	NNP
cord-002808-84np9brx	128	20	-	-	HYPH
cord-002808-84np9brx	128	21	sec	sec	NNP
cord-002808-84np9brx	128	22	inhibition	inhibition	NN
cord-002808-84np9brx	128	23	was	be	VBD
cord-002808-84np9brx	128	24	the	the	DT
cord-002808-84np9brx	128	25	most	most	RBS
cord-002808-84np9brx	128	26	conserved	conserve	VBN
cord-002808-84np9brx	128	27	feature	feature	NN
cord-002808-84np9brx	128	28	among	among	IN
cord-002808-84np9brx	128	29	the	the	DT
cord-002808-84np9brx	128	30	29	29	CD
cord-002808-84np9brx	128	31	alpha	alpha	NN
cord-002808-84np9brx	128	32	and	and	CC
cord-002808-84np9brx	128	33	5	5	CD
cord-002808-84np9brx	128	34	beta	beta	NN
cord-002808-84np9brx	128	35	HPV	HPV	NNP
cord-002808-84np9brx	128	36	types	type	NNS
cord-002808-84np9brx	128	37	tested	test	VBN
cord-002808-84np9brx	128	38	,	,	,
cord-002808-84np9brx	128	39	even	even	RB
cord-002808-84np9brx	128	40	higher	high	JJR
cord-002808-84np9brx	128	41	than	than	IN
cord-002808-84np9brx	128	42	sensitivity	sensitivity	NN
cord-002808-84np9brx	128	43	to	to	IN
cord-002808-84np9brx	128	44	furin	furin	NN
cord-002808-84np9brx	128	45	inhibition	inhibition	NN
cord-002808-84np9brx	128	46	[	[	-LRB-
cord-002808-84np9brx	128	47	72	72	CD
cord-002808-84np9brx	128	48	]	]	-RRB-
cord-002808-84np9brx	128	49	.	.	.
cord-002808-84np9brx	129	1	The	the	DT
cord-002808-84np9brx	129	2	molecular	molecular	JJ
cord-002808-84np9brx	129	3	basis	basis	NN
cord-002808-84np9brx	129	4	for	for	IN
cord-002808-84np9brx	129	5	the	the	DT
cord-002808-84np9brx	129	6	γ	γ	NNP
cord-002808-84np9brx	129	7	-	-	HYPH
cord-002808-84np9brx	129	8	sec	sec	NNP
cord-002808-84np9brx	129	9	requirement	requirement	NN
cord-002808-84np9brx	129	10	is	be	VBZ
cord-002808-84np9brx	129	11	unknown	unknown	JJ
cord-002808-84np9brx	129	12	,	,	,
cord-002808-84np9brx	129	13	but	but	CC
cord-002808-84np9brx	129	14	inhibition	inhibition	NN
cord-002808-84np9brx	129	15	of	of	IN
cord-002808-84np9brx	129	16	γ	γ	NNP
cord-002808-84np9brx	129	17	-	-	HYPH
cord-002808-84np9brx	129	18	sec	sec	NNP
cord-002808-84np9brx	129	19	activity	activity	NN
cord-002808-84np9brx	129	20	results	result	NNS
cord-002808-84np9brx	129	21	in	in	IN
cord-002808-84np9brx	129	22	a	a	DT
cord-002808-84np9brx	129	23	failure	failure	NN
cord-002808-84np9brx	129	24	of	of	IN
cord-002808-84np9brx	129	25	L2	l2	NN
cord-002808-84np9brx	129	26	/	/	,
cord-002808-84np9brx	129	27	vDNA	vdna	NN
cord-002808-84np9brx	129	28	to	to	TO
cord-002808-84np9brx	129	29	reach	reach	VB
cord-002808-84np9brx	129	30	the	the	DT
cord-002808-84np9brx	129	31	TGN	TGN	NNP
cord-002808-84np9brx	129	32	,	,	,
cord-002808-84np9brx	129	33	even	even	RB
cord-002808-84np9brx	129	34	though	though	IN
cord-002808-84np9brx	129	35	L2	L2	NNP
cord-002808-84np9brx	129	36	appears	appear	VBZ
cord-002808-84np9brx	129	37	to	to	TO
cord-002808-84np9brx	129	38	exit	exit	VB
cord-002808-84np9brx	129	39	EEA1	EEA1	NNP
cord-002808-84np9brx	129	40	positive	positive	JJ
cord-002808-84np9brx	129	41	endosomal	endosomal	NNP
cord-002808-84np9brx	129	42	compartments	compartment	NNS
cord-002808-84np9brx	129	43	[	[	-LRB-
cord-002808-84np9brx	129	44	55	55	CD
cord-002808-84np9brx	129	45	]	]	-RRB-
cord-002808-84np9brx	130	1	(	(	-LRB-
cord-002808-84np9brx	130	2	Figure	figure	NN
cord-002808-84np9brx	130	3	2	2	CD
cord-002808-84np9brx	130	4	)	)	-RRB-
cord-002808-84np9brx	130	5	.	.	.
cord-002808-84np9brx	131	1	This	this	DT
cord-002808-84np9brx	131	2	is	be	VBZ
cord-002808-84np9brx	131	3	in	in	IN
cord-002808-84np9brx	131	4	contrast	contrast	NN
cord-002808-84np9brx	131	5	to	to	IN
cord-002808-84np9brx	131	6	retromer	retromer	NNP
cord-002808-84np9brx	131	7	knockdown	knockdown	NN
cord-002808-84np9brx	131	8	,	,	,
cord-002808-84np9brx	131	9	which	which	WDT
cord-002808-84np9brx	131	10	causes	cause	VBZ
cord-002808-84np9brx	131	11	an	an	DT
cord-002808-84np9brx	131	12	accumulation	accumulation	NN
cord-002808-84np9brx	131	13	of	of	IN
cord-002808-84np9brx	131	14	vDNA	vdna	NN
cord-002808-84np9brx	131	15	within	within	IN
cord-002808-84np9brx	131	16	EEA1	EEA1	NNP
cord-002808-84np9brx	131	17	endosomes	endosome	NNS
cord-002808-84np9brx	131	18	[	[	-LRB-
cord-002808-84np9brx	131	19	48	48	CD
cord-002808-84np9brx	131	20	]	]	-RRB-
cord-002808-84np9brx	131	21	.	.	.
cord-002808-84np9brx	132	1	This	this	DT
cord-002808-84np9brx	132	2	may	may	MD
cord-002808-84np9brx	132	3	suggest	suggest	VB
cord-002808-84np9brx	132	4	that	that	IN
cord-002808-84np9brx	132	5	,	,	,
cord-002808-84np9brx	132	6	in	in	IN
cord-002808-84np9brx	132	7	the	the	DT
cord-002808-84np9brx	132	8	absence	absence	NN
cord-002808-84np9brx	132	9	of	of	IN
cord-002808-84np9brx	132	10	γ	γ	NNP
cord-002808-84np9brx	132	11	-	-	HYPH
cord-002808-84np9brx	132	12	sec	sec	NNP
cord-002808-84np9brx	132	13	activity	activity	NN
cord-002808-84np9brx	132	14	,	,	,
cord-002808-84np9brx	132	15	L2	L2	NNP
cord-002808-84np9brx	132	16	/	/	SYM
cord-002808-84np9brx	132	17	vDNA	vdna	RB
cord-002808-84np9brx	132	18	never	never	RB
cord-002808-84np9brx	132	19	exits	exit	VBZ
cord-002808-84np9brx	132	20	the	the	DT
cord-002808-84np9brx	132	21	MVB	MVB	NNP
cord-002808-84np9brx	132	22	/	/	SYM
cord-002808-84np9brx	132	23	LE	LE	NNP
cord-002808-84np9brx	132	24	compartments	compartment	NNS
cord-002808-84np9brx	132	25	,	,	,
cord-002808-84np9brx	132	26	and	and	CC
cord-002808-84np9brx	132	27	instead	instead	RB
cord-002808-84np9brx	132	28	continues	continue	VBZ
cord-002808-84np9brx	132	29	to	to	IN
cord-002808-84np9brx	132	30	lysosomes	lysosomes	VB
cord-002808-84np9brx	132	31	for	for	IN
cord-002808-84np9brx	132	32	degradation	degradation	NN
cord-002808-84np9brx	132	33	;	;	:
cord-002808-84np9brx	132	34	or	or	CC
cord-002808-84np9brx	132	35	that	that	IN
cord-002808-84np9brx	132	36	γ	γ	NNP
cord-002808-84np9brx	132	37	-	-	HYPH
cord-002808-84np9brx	132	38	sec	sec	NNP
cord-002808-84np9brx	132	39	controls	control	NNS
cord-002808-84np9brx	132	40	trafficking	trafficking	NN
cord-002808-84np9brx	132	41	of	of	IN
cord-002808-84np9brx	132	42	L2	l2	NN
cord-002808-84np9brx	132	43	/	/	,
cord-002808-84np9brx	132	44	vDNA	vdna	NN
cord-002808-84np9brx	132	45	to	to	IN
cord-002808-84np9brx	132	46	a	a	DT
cord-002808-84np9brx	132	47	discrete	discrete	JJ
cord-002808-84np9brx	132	48	intermediate	intermediate	JJ
cord-002808-84np9brx	132	49	compartment	compartment	NN
cord-002808-84np9brx	132	50	,	,	,
cord-002808-84np9brx	132	51	between	between	IN
cord-002808-84np9brx	132	52	the	the	DT
cord-002808-84np9brx	132	53	MVB	MVB	NNP
cord-002808-84np9brx	132	54	and	and	CC
cord-002808-84np9brx	132	55	the	the	DT
cord-002808-84np9brx	132	56	TGN	TGN	NNP
cord-002808-84np9brx	132	57	.	.	.
cord-002808-84np9brx	133	1	Consistent	consistent	JJ
cord-002808-84np9brx	133	2	with	with	IN
cord-002808-84np9brx	133	3	the	the	DT
cord-002808-84np9brx	133	4	observed	observed	JJ
cord-002808-84np9brx	133	5	effects	effect	NNS
cord-002808-84np9brx	133	6	on	on	IN
cord-002808-84np9brx	133	7	L2	L2	NNP
cord-002808-84np9brx	133	8	/	/	,
cord-002808-84np9brx	133	9	vDNA	vdna	NN
cord-002808-84np9brx	133	10	trafficking	trafficking	NN
cord-002808-84np9brx	133	11	,	,	,
cord-002808-84np9brx	133	12	HPV16	hpv16	NN
cord-002808-84np9brx	133	13	is	be	VBZ
cord-002808-84np9brx	133	14	only	only	RB
cord-002808-84np9brx	133	15	sensitive	sensitive	JJ
cord-002808-84np9brx	133	16	to	to	IN
cord-002808-84np9brx	133	17	γ	γ	NNP
cord-002808-84np9brx	133	18	-	-	HYPH
cord-002808-84np9brx	133	19	sec	sec	NNP
cord-002808-84np9brx	133	20	inhibition	inhibition	NN
cord-002808-84np9brx	133	21	during	during	IN
cord-002808-84np9brx	133	22	the	the	DT
cord-002808-84np9brx	133	23	first	first	JJ
cord-002808-84np9brx	133	24	6	6	CD
cord-002808-84np9brx	133	25	-	-	SYM
cord-002808-84np9brx	133	26	8	8	CD
cord-002808-84np9brx	133	27	h	h	NN
cord-002808-84np9brx	133	28	of	of	IN
cord-002808-84np9brx	133	29	infection	infection	NN
cord-002808-84np9brx	133	30	[	[	-LRB-
cord-002808-84np9brx	133	31	55	55	CD
cord-002808-84np9brx	133	32	]	]	-RRB-
cord-002808-84np9brx	133	33	,	,	,
cord-002808-84np9brx	133	34	and	and	CC
cord-002808-84np9brx	133	35	γ	γ	NNP
cord-002808-84np9brx	133	36	-	-	HYPH
cord-002808-84np9brx	133	37	sec	sec	NNP
cord-002808-84np9brx	133	38	inhibition	inhibition	NN
cord-002808-84np9brx	133	39	has	have	VBZ
cord-002808-84np9brx	133	40	no	no	DT
cord-002808-84np9brx	133	41	effect	effect	NN
cord-002808-84np9brx	133	42	on	on	IN
cord-002808-84np9brx	133	43	post	post	JJ
cord-002808-84np9brx	133	44	-	-	JJ
cord-002808-84np9brx	133	45	TGN	tgn	JJ
cord-002808-84np9brx	133	46	trafficking	trafficking	NN
cord-002808-84np9brx	133	47	of	of	IN
cord-002808-84np9brx	133	48	vDNA	vdna	DT
cord-002808-84np9brx	133	49	[	[	-LRB-
cord-002808-84np9brx	133	50	51	51	CD
cord-002808-84np9brx	133	51	]	]	-RRB-
cord-002808-84np9brx	133	52	.	.	.
cord-002808-84np9brx	134	1	Failure	failure	NN
cord-002808-84np9brx	134	2	of	of	IN
cord-002808-84np9brx	134	3	L2	L2	NNP
cord-002808-84np9brx	134	4	/	/	,
cord-002808-84np9brx	134	5	vDNA	vdna	NN
cord-002808-84np9brx	135	1	to	to	TO
cord-002808-84np9brx	135	2	reach	reach	VB
cord-002808-84np9brx	135	3	the	the	DT
cord-002808-84np9brx	135	4	TGN	TGN	NNP
cord-002808-84np9brx	135	5	in	in	IN
cord-002808-84np9brx	135	6	the	the	DT
cord-002808-84np9brx	135	7	absence	absence	NN
cord-002808-84np9brx	135	8	of	of	IN
cord-002808-84np9brx	135	9	γ	γ	NNP
cord-002808-84np9brx	135	10	-	-	HYPH
cord-002808-84np9brx	135	11	sec	sec	NNP
cord-002808-84np9brx	135	12	activity	activity	NN
cord-002808-84np9brx	135	13	means	mean	VBZ
cord-002808-84np9brx	135	14	that	that	IN
cord-002808-84np9brx	135	15	the	the	DT
cord-002808-84np9brx	135	16	retrograde	retrograde	JJ
cord-002808-84np9brx	135	17	trafficking	traffic	VBG
cord-002808-84np9brx	135	18	pathway	pathway	NN
cord-002808-84np9brx	135	19	utilized	utilize	VBN
cord-002808-84np9brx	135	20	by	by	IN
cord-002808-84np9brx	135	21	HPV	HPV	NNP
cord-002808-84np9brx	135	22	involves	involve	VBZ
cord-002808-84np9brx	135	23	more	more	JJR
cord-002808-84np9brx	135	24	than	than	IN
cord-002808-84np9brx	135	25	just	just	RB
cord-002808-84np9brx	135	26	the	the	DT
cord-002808-84np9brx	135	27	canonical	canonical	JJ
cord-002808-84np9brx	135	28	players	player	NNS
cord-002808-84np9brx	135	29	like	like	IN
cord-002808-84np9brx	135	30	retromer	retromer	NN
cord-002808-84np9brx	135	31	and	and	CC
cord-002808-84np9brx	135	32	SNXs	snx	NNS
cord-002808-84np9brx	135	33	,	,	,
cord-002808-84np9brx	135	34	suggesting	suggest	VBG
cord-002808-84np9brx	135	35	that	that	IN
cord-002808-84np9brx	135	36	new	new	JJ
cord-002808-84np9brx	135	37	γ	γ	NNP
cord-002808-84np9brx	135	38	-	-	HYPH
cord-002808-84np9brx	135	39	sec	sec	NNP
cord-002808-84np9brx	135	40	-	-	HYPH
cord-002808-84np9brx	135	41	dependent	dependent	JJ
cord-002808-84np9brx	135	42	retrograde	retrograde	JJ
cord-002808-84np9brx	135	43	pathways	pathway	NNS
cord-002808-84np9brx	135	44	may	may	MD
cord-002808-84np9brx	135	45	exist	exist	VB
cord-002808-84np9brx	135	46	and	and	CC
cord-002808-84np9brx	135	47	are	be	VBP
cord-002808-84np9brx	135	48	being	be	VBG
cord-002808-84np9brx	135	49	exploited	exploit	VBN
cord-002808-84np9brx	135	50	by	by	IN
cord-002808-84np9brx	135	51	papillomaviruses	papillomaviruse	NNS
cord-002808-84np9brx	135	52	.	.	.
cord-002808-84np9brx	136	1	The	the	DT
cord-002808-84np9brx	136	2	catalytic	catalytic	JJ
cord-002808-84np9brx	136	3	PS1/2	PS1/2	NNP
cord-002808-84np9brx	136	4	subunit	subunit	NN
cord-002808-84np9brx	136	5	of	of	IN
cord-002808-84np9brx	136	6	γ	γ	NNP
cord-002808-84np9brx	136	7	-	-	HYPH
cord-002808-84np9brx	136	8	sec	sec	NNP
cord-002808-84np9brx	136	9	are	be	VBP
cord-002808-84np9brx	136	10	known	know	VBN
cord-002808-84np9brx	136	11	to	to	TO
cord-002808-84np9brx	136	12	modulate	modulate	VB
cord-002808-84np9brx	136	13	protein	protein	NN
cord-002808-84np9brx	136	14	trafficking	trafficking	NN
cord-002808-84np9brx	136	15	,	,	,
cord-002808-84np9brx	136	16	lysosomal	lysosomal	JJ
cord-002808-84np9brx	136	17	maturation	maturation	NN
cord-002808-84np9brx	136	18	,	,	,
cord-002808-84np9brx	136	19	and	and	CC
cord-002808-84np9brx	136	20	Ca	Ca	NNP
cord-002808-84np9brx	136	21	2	2	CD
cord-002808-84np9brx	136	22	+	+	CC
cord-002808-84np9brx	136	23	homeostasis	homeostasis	NN
cord-002808-84np9brx	136	24	independently	independently	RB
cord-002808-84np9brx	136	25	of	of	IN
cord-002808-84np9brx	136	26	γ	γ	NNP
cord-002808-84np9brx	136	27	-	-	HYPH
cord-002808-84np9brx	136	28	sec	sec	NNP
cord-002808-84np9brx	136	29	-	-	HYPH
cord-002808-84np9brx	136	30	activity	activity	NN
cord-002808-84np9brx	136	31	,	,	,
cord-002808-84np9brx	136	32	but	but	CC
cord-002808-84np9brx	136	33	direct	direct	JJ
cord-002808-84np9brx	136	34	connections	connection	NNS
cord-002808-84np9brx	136	35	to	to	TO
cord-002808-84np9brx	136	36	retrograde	retrograde	VB
cord-002808-84np9brx	136	37	trafficking	traffic	VBG
cord-002808-84np9brx	136	38	pathways	pathway	NNS
cord-002808-84np9brx	137	1	are	be	VBP
cord-002808-84np9brx	137	2	scant	scant	JJ
cord-002808-84np9brx	137	3	[	[	-LRB-
cord-002808-84np9brx	137	4	73	73	CD
cord-002808-84np9brx	137	5	]	]	-RRB-
cord-002808-84np9brx	137	6	.	.	.
cord-002808-84np9brx	138	1	Retromer	Retromer	NNP
cord-002808-84np9brx	138	2	has	have	VBZ
cord-002808-84np9brx	138	3	,	,	,
cord-002808-84np9brx	138	4	however	however	RB
cord-002808-84np9brx	138	5	,	,	,
cord-002808-84np9brx	138	6	been	be	VBN
cord-002808-84np9brx	138	7	implicated	implicate	VBN
cord-002808-84np9brx	138	8	in	in	IN
cord-002808-84np9brx	138	9	retrograde	retrograde	JJ
cord-002808-84np9brx	138	10	-	-	HYPH
cord-002808-84np9brx	138	11	dependent	dependent	JJ
cord-002808-84np9brx	138	12	trafficking	trafficking	NN
cord-002808-84np9brx	138	13	and	and	CC
cord-002808-84np9brx	138	14	cleavage	cleavage	NN
cord-002808-84np9brx	138	15	of	of	IN
cord-002808-84np9brx	138	16	gamma	gamma	NNP
cord-002808-84np9brx	138	17	secretase	secretase	NNP
cord-002808-84np9brx	138	18	substrates	substrate	NNS
cord-002808-84np9brx	138	19	,	,	,
cord-002808-84np9brx	138	20	including	include	VBG
cord-002808-84np9brx	138	21	APP	app	NN
cord-002808-84np9brx	138	22	[	[	-LRB-
cord-002808-84np9brx	138	23	74	74	CD
cord-002808-84np9brx	138	24	,	,	,
cord-002808-84np9brx	138	25	75	75	CD
cord-002808-84np9brx	138	26	]	]	-RRB-
cord-002808-84np9brx	138	27	.	.	.
cord-002808-84np9brx	139	1	How	how	WRB
cord-002808-84np9brx	139	2	does	do	VBZ
cord-002808-84np9brx	139	3	L2	L2	NNP
cord-002808-84np9brx	139	4	,	,	,
cord-002808-84np9brx	139	5	the	the	DT
cord-002808-84np9brx	139	6	minor	minor	JJ
cord-002808-84np9brx	139	7	capsid	capsid	NN
cord-002808-84np9brx	139	8	protein	protein	NN
cord-002808-84np9brx	139	9	from	from	IN
cord-002808-84np9brx	139	10	a	a	DT
cord-002808-84np9brx	139	11	non	non	JJ
cord-002808-84np9brx	139	12	-	-	JJ
cord-002808-84np9brx	139	13	enveloped	enveloped	JJ
cord-002808-84np9brx	139	14	virus	virus	NN
cord-002808-84np9brx	139	15	,	,	,
cord-002808-84np9brx	139	16	complexed	complexe	VBN
cord-002808-84np9brx	139	17	with	with	IN
cord-002808-84np9brx	139	18	the	the	DT
cord-002808-84np9brx	139	19	vDNA	vdna	NN
cord-002808-84np9brx	139	20	within	within	IN
cord-002808-84np9brx	139	21	the	the	DT
cord-002808-84np9brx	139	22	lumen	lumen	NN
cord-002808-84np9brx	139	23	of	of	IN
cord-002808-84np9brx	139	24	intracellular	intracellular	JJ
cord-002808-84np9brx	139	25	vesicular	vesicular	JJ
cord-002808-84np9brx	139	26	compartments	compartment	NNS
cord-002808-84np9brx	139	27	,	,	,
cord-002808-84np9brx	139	28	interact	interact	VB
cord-002808-84np9brx	139	29	with	with	IN
cord-002808-84np9brx	139	30	a	a	DT
cord-002808-84np9brx	139	31	variety	variety	NN
cord-002808-84np9brx	139	32	of	of	IN
cord-002808-84np9brx	139	33	cytosolic	cytosolic	JJ
cord-002808-84np9brx	139	34	sorting	sorting	NN
cord-002808-84np9brx	139	35	molecules	molecule	NNS
cord-002808-84np9brx	139	36	to	to	TO
cord-002808-84np9brx	139	37	direct	direct	VB
cord-002808-84np9brx	139	38	its	-PRON-	PRP$
cord-002808-84np9brx	139	39	own	own	JJ
cord-002808-84np9brx	139	40	transport	transport	NN
cord-002808-84np9brx	139	41	to	to	IN
cord-002808-84np9brx	139	42	the	the	DT
cord-002808-84np9brx	139	43	TGN	TGN	NNP
cord-002808-84np9brx	139	44	?	?	.
cord-002808-84np9brx	140	1	Evidence	evidence	NN
cord-002808-84np9brx	140	2	from	from	IN
cord-002808-84np9brx	140	3	multiple	multiple	JJ
cord-002808-84np9brx	140	4	laboratories	laboratory	NNS
cord-002808-84np9brx	140	5	suggests	suggest	VBZ
cord-002808-84np9brx	140	6	that	that	IN
cord-002808-84np9brx	140	7	L2	L2	NNP
cord-002808-84np9brx	140	8	can	can	MD
cord-002808-84np9brx	140	9	interact	interact	VB
cord-002808-84np9brx	140	10	with	with	IN
cord-002808-84np9brx	140	11	and	and	CC
cord-002808-84np9brx	140	12	span	span	VB
cord-002808-84np9brx	140	13	across	across	IN
cord-002808-84np9brx	140	14	vesicular	vesicular	JJ
cord-002808-84np9brx	140	15	membranes	membrane	NNS
cord-002808-84np9brx	140	16	,	,	,
cord-002808-84np9brx	140	17	thereby	thereby	RB
cord-002808-84np9brx	140	18	allowing	allow	VBG
cord-002808-84np9brx	140	19	L2	L2	NNP
cord-002808-84np9brx	140	20	to	to	TO
cord-002808-84np9brx	140	21	gain	gain	VB
cord-002808-84np9brx	140	22	access	access	NN
cord-002808-84np9brx	140	23	to	to	IN
cord-002808-84np9brx	140	24	the	the	DT
cord-002808-84np9brx	140	25	cytosol	cytosol	NN
cord-002808-84np9brx	140	26	,	,	,
cord-002808-84np9brx	140	27	to	to	TO
cord-002808-84np9brx	140	28	recruit	recruit	VB
cord-002808-84np9brx	140	29	cytosolic	cytosolic	JJ
cord-002808-84np9brx	140	30	factors	factor	NNS
cord-002808-84np9brx	140	31	necessary	necessary	JJ
cord-002808-84np9brx	140	32	for	for	IN
cord-002808-84np9brx	140	33	retrograde	retrograde	JJ
cord-002808-84np9brx	140	34	trafficking	trafficking	NN
cord-002808-84np9brx	140	35	(	(	-LRB-
cord-002808-84np9brx	140	36	Figure	figure	NN
cord-002808-84np9brx	140	37	2	2	CD
cord-002808-84np9brx	140	38	)	)	-RRB-
cord-002808-84np9brx	140	39	.	.	.
cord-002808-84np9brx	141	1	Post	Post	NNP
cord-002808-84np9brx	141	2	-	-	JJ
cord-002808-84np9brx	141	3	TGN	TGN	NNP
cord-002808-84np9brx	141	4	transit	transit	NN
cord-002808-84np9brx	141	5	,	,	,
cord-002808-84np9brx	141	6	full	full	JJ
cord-002808-84np9brx	141	7	translocation	translocation	NN
cord-002808-84np9brx	141	8	across	across	IN
cord-002808-84np9brx	141	9	the	the	DT
cord-002808-84np9brx	141	10	limiting	limit	VBG
cord-002808-84np9brx	141	11	membrane	membrane	NN
cord-002808-84np9brx	141	12	,	,	,
cord-002808-84np9brx	141	13	and	and	CC
cord-002808-84np9brx	141	14	nuclear	nuclear	JJ
cord-002808-84np9brx	141	15	accumulation	accumulation	NN
cord-002808-84np9brx	141	16	of	of	IN
cord-002808-84np9brx	141	17	the	the	DT
cord-002808-84np9brx	141	18	L2	L2	NNP
cord-002808-84np9brx	141	19	/	/	SYM
cord-002808-84np9brx	141	20	vDNA	vdna	RB
cord-002808-84np9brx	141	21	complex	complex	NNP
cord-002808-84np9brx	141	22	requires	require	VBZ
cord-002808-84np9brx	141	23	mitosis	mitosis	NN
cord-002808-84np9brx	141	24	and	and	CC
cord-002808-84np9brx	141	25	is	be	VBZ
cord-002808-84np9brx	141	26	summarized	summarize	VBN
cord-002808-84np9brx	141	27	in	in	IN
cord-002808-84np9brx	141	28	greater	great	JJR
cord-002808-84np9brx	141	29	detail	detail	NN
cord-002808-84np9brx	141	30	in	in	IN
cord-002808-84np9brx	141	31	latter	latter	JJ
cord-002808-84np9brx	141	32	sections	section	NNS
cord-002808-84np9brx	141	33	of	of	IN
cord-002808-84np9brx	141	34	this	this	DT
cord-002808-84np9brx	141	35	review	review	NN
cord-002808-84np9brx	141	36	.	.	.
cord-002808-84np9brx	142	1	For	for	IN
cord-002808-84np9brx	142	2	the	the	DT
cord-002808-84np9brx	142	3	sake	sake	NN
cord-002808-84np9brx	142	4	of	of	IN
cord-002808-84np9brx	142	5	consistency	consistency	NN
cord-002808-84np9brx	142	6	within	within	IN
cord-002808-84np9brx	142	7	the	the	DT
cord-002808-84np9brx	142	8	field	field	NN
cord-002808-84np9brx	142	9	,	,	,
cord-002808-84np9brx	142	10	the	the	DT
cord-002808-84np9brx	142	11	following	following	JJ
cord-002808-84np9brx	142	12	nomenclature	nomenclature	NN
cord-002808-84np9brx	142	13	is	be	VBZ
cord-002808-84np9brx	142	14	proposed	propose	VBN
cord-002808-84np9brx	142	15	for	for	IN
cord-002808-84np9brx	142	16	the	the	DT
cord-002808-84np9brx	142	17	3-step	3-step	NNP
cord-002808-84np9brx	142	18	process	process	NN
cord-002808-84np9brx	142	19	describing	describe	VBG
cord-002808-84np9brx	142	20	L2	L2	NNP
cord-002808-84np9brx	142	21	's	's	POS
cord-002808-84np9brx	142	22	remarkable	remarkable	JJ
cord-002808-84np9brx	142	23	ability	ability	NN
cord-002808-84np9brx	142	24	to	to	TO
cord-002808-84np9brx	142	25	shift	shift	VB
cord-002808-84np9brx	142	26	from	from	IN
cord-002808-84np9brx	142	27	being	be	VBG
cord-002808-84np9brx	142	28	a	a	DT
cord-002808-84np9brx	142	29	soluble	soluble	JJ
cord-002808-84np9brx	142	30	protein	protein	NN
cord-002808-84np9brx	142	31	to	to	IN
cord-002808-84np9brx	142	32	a	a	DT
cord-002808-84np9brx	142	33	transmembrane	transmembrane	NN
cord-002808-84np9brx	142	34	protein	protein	NN
cord-002808-84np9brx	142	35	and	and	CC
cord-002808-84np9brx	142	36	back	back	NN
cord-002808-84np9brx	142	37	again	again	RB
cord-002808-84np9brx	142	38	:	:	:
cord-002808-84np9brx	142	39	(	(	-LRB-
cord-002808-84np9brx	142	40	1	1	LS
cord-002808-84np9brx	142	41	)	)	-RRB-
cord-002808-84np9brx	142	42	Insertion	insertion	NN
cord-002808-84np9brx	142	43	-	-	,
cord-002808-84np9brx	142	44	Within	within	IN
cord-002808-84np9brx	142	45	the	the	DT
cord-002808-84np9brx	142	46	lumen	lumen	NN
cord-002808-84np9brx	142	47	,	,	,
cord-002808-84np9brx	142	48	part(s	part(s	NNP
cord-002808-84np9brx	142	49	)	)	-RRB-
cord-002808-84np9brx	142	50	of	of	IN
cord-002808-84np9brx	142	51	L2	L2	NNP
cord-002808-84np9brx	142	52	insert(s	insert(s	NNP
cord-002808-84np9brx	142	53	)	)	-RRB-
cord-002808-84np9brx	142	54	into	into	IN
cord-002808-84np9brx	142	55	the	the	DT
cord-002808-84np9brx	142	56	local	local	JJ
cord-002808-84np9brx	142	57	membrane	membrane	NN
cord-002808-84np9brx	142	58	.	.	.
cord-002808-84np9brx	142	59	 	 	_SP
cord-002808-84np9brx	143	1	How	how	WRB
cord-002808-84np9brx	143	2	does	do	VBZ
cord-002808-84np9brx	143	3	the	the	DT
cord-002808-84np9brx	143	4	L2	L2	NNP
cord-002808-84np9brx	143	5	protein	protein	NN
cord-002808-84np9brx	143	6	initially	initially	RB
cord-002808-84np9brx	143	7	interact	interact	VBP
cord-002808-84np9brx	143	8	with	with	IN
cord-002808-84np9brx	143	9	and	and	CC
cord-002808-84np9brx	143	10	insert	insert	VB
cord-002808-84np9brx	143	11	into	into	IN
cord-002808-84np9brx	143	12	membranes	membrane	NNS
cord-002808-84np9brx	143	13	?	?	.
cord-002808-84np9brx	144	1	When	when	WRB
cord-002808-84np9brx	144	2	naturally	naturally	RB
cord-002808-84np9brx	144	3	or	or	CC
cord-002808-84np9brx	144	4	ectopically	ectopically	RB
cord-002808-84np9brx	144	5	expressed	express	VBN
cord-002808-84np9brx	144	6	,	,	,
cord-002808-84np9brx	144	7	L2	L2	NNP
cord-002808-84np9brx	144	8	is	be	VBZ
cord-002808-84np9brx	144	9	a	a	DT
cord-002808-84np9brx	144	10	soluble	soluble	JJ
cord-002808-84np9brx	144	11	nuclear	nuclear	JJ
cord-002808-84np9brx	144	12	protein	protein	NN
cord-002808-84np9brx	144	13	,	,	,
cord-002808-84np9brx	144	14	not	not	RB
cord-002808-84np9brx	144	15	a	a	DT
cord-002808-84np9brx	144	16	membrane	membrane	NN
cord-002808-84np9brx	144	17	protein	protein	NN
cord-002808-84np9brx	144	18	[	[	-LRB-
cord-002808-84np9brx	144	19	76	76	CD
cord-002808-84np9brx	144	20	,	,	,
cord-002808-84np9brx	144	21	77	77	CD
cord-002808-84np9brx	144	22	]	]	-RRB-
cord-002808-84np9brx	144	23	.	.	.
cord-002808-84np9brx	145	1	Yet	yet	RB
cord-002808-84np9brx	145	2	,	,	,
cord-002808-84np9brx	145	3	during	during	IN
cord-002808-84np9brx	145	4	infection	infection	NN
cord-002808-84np9brx	145	5	,	,	,
cord-002808-84np9brx	145	6	L2	L2	NNP
cord-002808-84np9brx	145	7	must	must	MD
cord-002808-84np9brx	145	8	somehow	somehow	RB
cord-002808-84np9brx	145	9	interact	interact	VB
cord-002808-84np9brx	145	10	with	with	IN
cord-002808-84np9brx	145	11	and	and	CC
cord-002808-84np9brx	145	12	cross	cross	NN
cord-002808-84np9brx	145	13	membranes	membrane	NNS
cord-002808-84np9brx	145	14	;	;	:
cord-002808-84np9brx	145	15	how	how	WRB
cord-002808-84np9brx	145	16	is	be	VBZ
cord-002808-84np9brx	145	17	this	this	DT
cord-002808-84np9brx	145	18	accomplished	accomplished	JJ
cord-002808-84np9brx	145	19	?	?	.
cord-002808-84np9brx	146	1	In	in	IN
cord-002808-84np9brx	146	2	2006	2006	CD
cord-002808-84np9brx	146	3	,	,	,
cord-002808-84np9brx	146	4	a	a	DT
cord-002808-84np9brx	146	5	conserved	conserved	JJ
cord-002808-84np9brx	146	6	"	"	``
cord-002808-84np9brx	146	7	membrane	membrane	NN
cord-002808-84np9brx	146	8	destabilizing	destabilize	VBG
cord-002808-84np9brx	146	9	peptide	peptide	NN
cord-002808-84np9brx	146	10	"	"	''
cord-002808-84np9brx	146	11	near	near	IN
cord-002808-84np9brx	146	12	the	the	DT
cord-002808-84np9brx	146	13	C	c	NN
cord-002808-84np9brx	146	14	-	-	HYPH
cord-002808-84np9brx	146	15	terminus	terminus	NN
cord-002808-84np9brx	146	16	of	of	IN
cord-002808-84np9brx	146	17	L2	L2	NNP
cord-002808-84np9brx	147	1	(	(	-LRB-
cord-002808-84np9brx	147	2	SYYMLRKRRKRLPY	SYYMLRKRRKRLPY	NNP
cord-002808-84np9brx	147	3	,	,	,
cord-002808-84np9brx	147	4	residues	residue	NNS
cord-002808-84np9brx	147	5	451	451	CD
cord-002808-84np9brx	147	6	-	-	SYM
cord-002808-84np9brx	147	7	464	464	CD
cord-002808-84np9brx	147	8	for	for	IN
cord-002808-84np9brx	147	9	HPV16	hpv16	NN
cord-002808-84np9brx	147	10	,	,	,
cord-002808-84np9brx	147	11	see	see	VB
cord-002808-84np9brx	147	12	Figure	figure	NN
cord-002808-84np9brx	147	13	1	1	CD
cord-002808-84np9brx	147	14	)	)	-RRB-
cord-002808-84np9brx	147	15	was	be	VBD
cord-002808-84np9brx	147	16	identified	identify	VBN
cord-002808-84np9brx	147	17	as	as	IN
cord-002808-84np9brx	147	18	having	have	VBG
cord-002808-84np9brx	147	19	a	a	DT
cord-002808-84np9brx	147	20	role	role	NN
cord-002808-84np9brx	147	21	in	in	IN
cord-002808-84np9brx	147	22	the	the	DT
cord-002808-84np9brx	147	23	endosomal	endosomal	NNP
cord-002808-84np9brx	147	24	escape	escape	NN
cord-002808-84np9brx	147	25	of	of	IN
cord-002808-84np9brx	147	26	L2	l2	NN
cord-002808-84np9brx	147	27	/	/	,
cord-002808-84np9brx	147	28	vDNA	vdna	NN
cord-002808-84np9brx	147	29	via	via	IN
cord-002808-84np9brx	147	30	membrane	membrane	NN
cord-002808-84np9brx	147	31	disruption	disruption	NN
cord-002808-84np9brx	147	32	or	or	CC
cord-002808-84np9brx	147	33	destabilization	destabilization	NN
cord-002808-84np9brx	147	34	[	[	-LRB-
cord-002808-84np9brx	147	35	78	78	CD
cord-002808-84np9brx	147	36	]	]	-RRB-
cord-002808-84np9brx	147	37	.	.	.
cord-002808-84np9brx	148	1	Using	use	VBG
cord-002808-84np9brx	148	2	synthetic	synthetic	JJ
cord-002808-84np9brx	148	3	C	c	NN
cord-002808-84np9brx	148	4	-	-	HYPH
cord-002808-84np9brx	148	5	terminal	terminal	NN
cord-002808-84np9brx	148	6	peptides	peptide	NNS
cord-002808-84np9brx	148	7	from	from	IN
cord-002808-84np9brx	148	8	HPV33	HPV33	NNP
cord-002808-84np9brx	148	9	L2	L2	NNP
cord-002808-84np9brx	148	10	,	,	,
cord-002808-84np9brx	148	11	containing	contain	VBG
cord-002808-84np9brx	148	12	the	the	DT
cord-002808-84np9brx	148	13	corresponding	correspond	VBG
cord-002808-84np9brx	148	14	membrane	membrane	NN
cord-002808-84np9brx	148	15	destabilization	destabilization	NN
cord-002808-84np9brx	148	16	moiety	moiety	NN
cord-002808-84np9brx	148	17	(	(	-LRB-
cord-002808-84np9brx	148	18	SYFILRRRRKRFPYFFTDVRVAA	SYFILRRRRKRFPYFFTDVRVAA	NNP
cord-002808-84np9brx	148	19	,	,	,
cord-002808-84np9brx	148	20	residues	residue	VBZ
cord-002808-84np9brx	148	21	445	445	CD
cord-002808-84np9brx	148	22	-	-	SYM
cord-002808-84np9brx	148	23	467	467	CD
cord-002808-84np9brx	148	24	)	)	-RRB-
cord-002808-84np9brx	148	25	,	,	,
cord-002808-84np9brx	148	26	in	in	IN
cord-002808-84np9brx	148	27	vitro	vitro	FW
cord-002808-84np9brx	148	28	cytotoxicity	cytotoxicity	NN
cord-002808-84np9brx	148	29	and	and	CC
cord-002808-84np9brx	148	30	propidium	propidium	NN
cord-002808-84np9brx	148	31	iodide	iodide	NN
cord-002808-84np9brx	148	32	uptake	uptake	NN
cord-002808-84np9brx	148	33	experiments	experiment	NNS
cord-002808-84np9brx	148	34	showed	show	VBD
cord-002808-84np9brx	148	35	a	a	DT
cord-002808-84np9brx	148	36	pH	ph	NN
cord-002808-84np9brx	148	37	-	-	HYPH
cord-002808-84np9brx	148	38	dependent	dependent	JJ
cord-002808-84np9brx	148	39	ability	ability	NN
cord-002808-84np9brx	148	40	to	to	TO
cord-002808-84np9brx	148	41	disrupt	disrupt	VB
cord-002808-84np9brx	148	42	cellular	cellular	JJ
cord-002808-84np9brx	148	43	membranes	membrane	NNS
cord-002808-84np9brx	148	44	.	.	.
cord-002808-84np9brx	149	1	While	while	IN
cord-002808-84np9brx	149	2	it	-PRON-	PRP
cord-002808-84np9brx	149	3	is	be	VBZ
cord-002808-84np9brx	149	4	possible	possible	JJ
cord-002808-84np9brx	149	5	that	that	IN
cord-002808-84np9brx	149	6	this	this	DT
cord-002808-84np9brx	149	7	C	c	NN
cord-002808-84np9brx	149	8	-	-	HYPH
cord-002808-84np9brx	149	9	terminal	terminal	NN
cord-002808-84np9brx	149	10	region	region	NN
cord-002808-84np9brx	149	11	aids	aids	NNP
cord-002808-84np9brx	149	12	in	in	IN
cord-002808-84np9brx	149	13	membrane	membrane	NN
cord-002808-84np9brx	149	14	insertion	insertion	NN
cord-002808-84np9brx	149	15	of	of	IN
cord-002808-84np9brx	149	16	L2	l2	NN
cord-002808-84np9brx	149	17	within	within	IN
cord-002808-84np9brx	149	18	the	the	DT
cord-002808-84np9brx	149	19	acidic	acidic	JJ
cord-002808-84np9brx	149	20	endosomes	endosome	NNS
cord-002808-84np9brx	149	21	,	,	,
cord-002808-84np9brx	149	22	it	-PRON-	PRP
cord-002808-84np9brx	149	23	is	be	VBZ
cord-002808-84np9brx	149	24	important	important	JJ
cord-002808-84np9brx	149	25	to	to	TO
cord-002808-84np9brx	149	26	note	note	VB
cord-002808-84np9brx	149	27	that	that	IN
cord-002808-84np9brx	149	28	a	a	DT
cord-002808-84np9brx	149	29	direct	direct	JJ
cord-002808-84np9brx	149	30	role	role	NN
cord-002808-84np9brx	149	31	in	in	IN
cord-002808-84np9brx	149	32	L2	L2	NNP
cord-002808-84np9brx	149	33	membrane	membrane	NN
cord-002808-84np9brx	149	34	insertion	insertion	NN
cord-002808-84np9brx	149	35	has	have	VBZ
cord-002808-84np9brx	149	36	yet	yet	RB
cord-002808-84np9brx	149	37	to	to	TO
cord-002808-84np9brx	149	38	be	be	VB
cord-002808-84np9brx	149	39	demonstrated	demonstrate	VBN
cord-002808-84np9brx	149	40	.	.	.
cord-002808-84np9brx	150	1	Regardless	regardless	RB
cord-002808-84np9brx	150	2	of	of	IN
cord-002808-84np9brx	150	3	how	how	WRB
cord-002808-84np9brx	150	4	L2	L2	NNP
cord-002808-84np9brx	150	5	initially	initially	RB
cord-002808-84np9brx	150	6	inserts	insert	VBZ
cord-002808-84np9brx	150	7	into	into	IN
cord-002808-84np9brx	150	8	membranes	membrane	NNS
cord-002808-84np9brx	150	9	during	during	IN
cord-002808-84np9brx	150	10	infection	infection	NN
cord-002808-84np9brx	150	11	,	,	,
cord-002808-84np9brx	150	12	multiple	multiple	JJ
cord-002808-84np9brx	150	13	groups	group	NNS
cord-002808-84np9brx	150	14	have	have	VBP
cord-002808-84np9brx	150	15	published	publish	VBN
cord-002808-84np9brx	150	16	indirect	indirect	JJ
cord-002808-84np9brx	150	17	evidence	evidence	NN
cord-002808-84np9brx	150	18	that	that	IN
cord-002808-84np9brx	150	19	L2	L2	NNP
cord-002808-84np9brx	150	20	interacts	interact	VBZ
cord-002808-84np9brx	150	21	with	with	IN
cord-002808-84np9brx	150	22	cytosolic	cytosolic	JJ
cord-002808-84np9brx	150	23	factors	factor	NNS
cord-002808-84np9brx	150	24	and	and	CC
cord-002808-84np9brx	150	25	thus	thus	RB
cord-002808-84np9brx	150	26	must	must	MD
cord-002808-84np9brx	150	27	protrude	protrude	VB
cord-002808-84np9brx	150	28	into	into	IN
cord-002808-84np9brx	150	29	the	the	DT
cord-002808-84np9brx	150	30	cytosol	cytosol	NN
cord-002808-84np9brx	150	31	across	across	IN
cord-002808-84np9brx	150	32	vesicular	vesicular	JJ
cord-002808-84np9brx	150	33	membranes	membrane	NNS
cord-002808-84np9brx	150	34	.	.	.
cord-002808-84np9brx	151	1	In	in	IN
cord-002808-84np9brx	151	2	2013	2013	CD
cord-002808-84np9brx	151	3	,	,	,
cord-002808-84np9brx	151	4	my	-PRON-	PRP$
cord-002808-84np9brx	151	5	laboratory	laboratory	NN
cord-002808-84np9brx	151	6	identified	identify	VBD
cord-002808-84np9brx	151	7	a	a	DT
cord-002808-84np9brx	151	8	glycine	glycine	NN
cord-002808-84np9brx	151	9	-	-	HYPH
cord-002808-84np9brx	151	10	rich	rich	JJ
cord-002808-84np9brx	151	11	transmembrane	transmembrane	NN
cord-002808-84np9brx	151	12	-	-	HYPH
cord-002808-84np9brx	151	13	like	like	JJ
cord-002808-84np9brx	151	14	domain	domain	NN
cord-002808-84np9brx	151	15	(	(	-LRB-
cord-002808-84np9brx	151	16	TMD	TMD	NNP
cord-002808-84np9brx	151	17	)	)	-RRB-
cord-002808-84np9brx	151	18	towards	towards	IN
cord-002808-84np9brx	151	19	the	the	DT
cord-002808-84np9brx	151	20	N	n	CD
cord-002808-84np9brx	151	21	-	-	HYPH
cord-002808-84np9brx	151	22	terminus	terminus	NN
cord-002808-84np9brx	151	23	of	of	IN
cord-002808-84np9brx	151	24	L2	L2	NNP
cord-002808-84np9brx	151	25	(	(	-LRB-
cord-002808-84np9brx	151	26	ILQYGSMGVFFGGLGIGTGSGTG	ILQYGSMGVFFGGLGIGTGSGTG	NNP
cord-002808-84np9brx	151	27	,	,	,
cord-002808-84np9brx	151	28	residues	residue	VBZ
cord-002808-84np9brx	151	29	45	45	CD
cord-002808-84np9brx	151	30	-	-	SYM
cord-002808-84np9brx	151	31	67	67	CD
cord-002808-84np9brx	151	32	of	of	IN
cord-002808-84np9brx	151	33	HPV16	hpv16	NN
cord-002808-84np9brx	151	34	,	,	,
cord-002808-84np9brx	151	35	see	see	VB
cord-002808-84np9brx	151	36	Figure	figure	NN
cord-002808-84np9brx	151	37	1	1	CD
cord-002808-84np9brx	151	38	)	)	-RRB-
cord-002808-84np9brx	151	39	[	[	-LRB-
cord-002808-84np9brx	151	40	79	79	CD
cord-002808-84np9brx	151	41	]	]	-RRB-
cord-002808-84np9brx	151	42	.	.	.
cord-002808-84np9brx	152	1	Taking	take	VBG
cord-002808-84np9brx	152	2	advantage	advantage	NN
cord-002808-84np9brx	152	3	of	of	IN
cord-002808-84np9brx	152	4	TMD	TMD	NNP
cord-002808-84np9brx	152	5	-	-	HYPH
cord-002808-84np9brx	152	6	flanking	flank	VBG
cord-002808-84np9brx	152	7	monoclonal	monoclonal	JJ
cord-002808-84np9brx	152	8	antibody	antibody	NN
cord-002808-84np9brx	152	9	epitopes	epitope	NNS
cord-002808-84np9brx	152	10	and	and	CC
cord-002808-84np9brx	152	11	using	use	VBG
cord-002808-84np9brx	152	12	elegant	elegant	JJ
cord-002808-84np9brx	152	13	immunofluorescence	immunofluorescence	NN
cord-002808-84np9brx	152	14	staining	stain	VBG
cord-002808-84np9brx	152	15	procedures	procedure	NNS
cord-002808-84np9brx	152	16	,	,	,
cord-002808-84np9brx	152	17	the	the	DT
cord-002808-84np9brx	152	18	Sapp	Sapp	NNP
cord-002808-84np9brx	152	19	laboratory	laboratory	NN
cord-002808-84np9brx	152	20	has	have	VBZ
cord-002808-84np9brx	152	21	since	since	IN
cord-002808-84np9brx	152	22	demonstrated	demonstrate	VBN
cord-002808-84np9brx	152	23	that	that	IN
cord-002808-84np9brx	152	24	L2	L2	NNP
cord-002808-84np9brx	152	25	utilizes	utilize	VBZ
cord-002808-84np9brx	152	26	this	this	DT
cord-002808-84np9brx	152	27	TMD	TMD	NNP
cord-002808-84np9brx	152	28	to	to	TO
cord-002808-84np9brx	152	29	span	span	VB
cord-002808-84np9brx	152	30	intracellular	intracellular	JJ
cord-002808-84np9brx	152	31	vesicular	vesicular	JJ
cord-002808-84np9brx	152	32	membranes	membrane	NNS
cord-002808-84np9brx	152	33	with	with	IN
cord-002808-84np9brx	152	34	residues	residue	NNS
cord-002808-84np9brx	152	35	C	c	NN
cord-002808-84np9brx	152	36	-	-	HYPH
cord-002808-84np9brx	152	37	terminal	terminal	NN
cord-002808-84np9brx	152	38	of	of	IN
cord-002808-84np9brx	152	39	the	the	DT
cord-002808-84np9brx	152	40	TMD	TMD	NNP
cord-002808-84np9brx	152	41	being	be	VBG
cord-002808-84np9brx	152	42	cytosolic	cytosolic	JJ
cord-002808-84np9brx	152	43	,	,	,
cord-002808-84np9brx	152	44	consistent	consistent	JJ
cord-002808-84np9brx	152	45	with	with	IN
cord-002808-84np9brx	152	46	a	a	DT
cord-002808-84np9brx	152	47	type	type	NN
cord-002808-84np9brx	152	48	-	-	:
cord-002808-84np9brx	152	49	I	i	NN
cord-002808-84np9brx	152	50	transmembrane	transmembrane	NN
cord-002808-84np9brx	152	51	topology	topology	NN
cord-002808-84np9brx	152	52	[	[	-LRB-
cord-002808-84np9brx	152	53	80	80	CD
cord-002808-84np9brx	152	54	]	]	-RRB-
cord-002808-84np9brx	152	55	.	.	.
cord-002808-84np9brx	153	1	Moreover	moreover	RB
cord-002808-84np9brx	153	2	,	,	,
cord-002808-84np9brx	153	3	additional	additional	JJ
cord-002808-84np9brx	153	4	data	datum	NNS
cord-002808-84np9brx	153	5	from	from	IN
cord-002808-84np9brx	153	6	the	the	DT
cord-002808-84np9brx	153	7	Sapp	Sapp	NNP
cord-002808-84np9brx	153	8	laboratory	laboratory	NN
cord-002808-84np9brx	153	9	suggest	suggest	VBP
cord-002808-84np9brx	153	10	the	the	DT
cord-002808-84np9brx	153	11	vDNA	vdna	RB
cord-002808-84np9brx	153	12	remains	remain	VBZ
cord-002808-84np9brx	153	13	lumenal	lumenal	JJ
cord-002808-84np9brx	153	14	within	within	IN
cord-002808-84np9brx	153	15	these	these	DT
cord-002808-84np9brx	153	16	intracellular	intracellular	JJ
cord-002808-84np9brx	153	17	vesicles	vesicle	NNS
cord-002808-84np9brx	153	18	[	[	-LRB-
cord-002808-84np9brx	153	19	81	81	CD
cord-002808-84np9brx	153	20	]	]	-RRB-
cord-002808-84np9brx	153	21	.	.	.
cord-002808-84np9brx	154	1	Exactly	exactly	RB
cord-002808-84np9brx	154	2	how	how	WRB
cord-002808-84np9brx	154	3	L2	L2	NNP
cord-002808-84np9brx	154	4	is	be	VBZ
cord-002808-84np9brx	154	5	able	able	JJ
cord-002808-84np9brx	154	6	to	to	TO
cord-002808-84np9brx	154	7	insert	insert	VB
cord-002808-84np9brx	154	8	into	into	IN
cord-002808-84np9brx	154	9	the	the	DT
cord-002808-84np9brx	154	10	membrane	membrane	NN
cord-002808-84np9brx	154	11	and	and	CC
cord-002808-84np9brx	154	12	span	span	NN
cord-002808-84np9brx	154	13	across	across	IN
cord-002808-84np9brx	154	14	remains	remain	NNS
cord-002808-84np9brx	154	15	unknown	unknown	JJ
cord-002808-84np9brx	154	16	,	,	,
cord-002808-84np9brx	154	17	but	but	CC
cord-002808-84np9brx	154	18	endosomal	endosomal	JJ
cord-002808-84np9brx	154	19	acidification	acidification	NN
cord-002808-84np9brx	154	20	seems	seem	VBZ
cord-002808-84np9brx	154	21	to	to	TO
cord-002808-84np9brx	154	22	be	be	VB
cord-002808-84np9brx	154	23	required	require	VBN
cord-002808-84np9brx	154	24	to	to	TO
cord-002808-84np9brx	154	25	adopt	adopt	VB
cord-002808-84np9brx	154	26	this	this	DT
cord-002808-84np9brx	154	27	conformation	conformation	NN
cord-002808-84np9brx	154	28	[	[	-LRB-
cord-002808-84np9brx	154	29	80	80	CD
cord-002808-84np9brx	154	30	]	]	-RRB-
cord-002808-84np9brx	154	31	,	,	,
cord-002808-84np9brx	154	32	although	although	IN
cord-002808-84np9brx	154	33	it	-PRON-	PRP
cord-002808-84np9brx	154	34	remains	remain	VBZ
cord-002808-84np9brx	154	35	to	to	TO
cord-002808-84np9brx	154	36	be	be	VB
cord-002808-84np9brx	154	37	determined	determine	VBN
cord-002808-84np9brx	154	38	if	if	IN
cord-002808-84np9brx	154	39	this	this	DT
cord-002808-84np9brx	154	40	may	may	MD
cord-002808-84np9brx	154	41	simply	simply	RB
cord-002808-84np9brx	154	42	reflect	reflect	VB
cord-002808-84np9brx	154	43	a	a	DT
cord-002808-84np9brx	154	44	requirement	requirement	NN
cord-002808-84np9brx	154	45	for	for	IN
cord-002808-84np9brx	154	46	L1	L1	NNP
cord-002808-84np9brx	154	47	capsid	capsid	NN
cord-002808-84np9brx	154	48	disassembly	disassembly	NN
cord-002808-84np9brx	154	49	or	or	CC
cord-002808-84np9brx	154	50	L1	L1	NNP
cord-002808-84np9brx	154	51	/	/	SYM
cord-002808-84np9brx	154	52	L2	l2	NN
cord-002808-84np9brx	154	53	partitioning	partitioning	NN
cord-002808-84np9brx	154	54	,	,	,
cord-002808-84np9brx	154	55	rather	rather	RB
cord-002808-84np9brx	154	56	than	than	IN
cord-002808-84np9brx	154	57	low	low	JJ
cord-002808-84np9brx	154	58	pH	pH	NNP
cord-002808-84np9brx	154	59	having	have	VBG
cord-002808-84np9brx	154	60	a	a	DT
cord-002808-84np9brx	154	61	direct	direct	JJ
cord-002808-84np9brx	154	62	effect	effect	NN
cord-002808-84np9brx	154	63	on	on	IN
cord-002808-84np9brx	154	64	L2	L2	NNP
cord-002808-84np9brx	154	65	protein	protein	NN
cord-002808-84np9brx	154	66	structure	structure	NN
cord-002808-84np9brx	154	67	or	or	CC
cord-002808-84np9brx	154	68	conformation	conformation	NN
cord-002808-84np9brx	154	69	.	.	.
cord-002808-84np9brx	155	1	Thus	thus	RB
cord-002808-84np9brx	155	2	,	,	,
cord-002808-84np9brx	155	3	virion	virion	NN
cord-002808-84np9brx	155	4	-	-	HYPH
cord-002808-84np9brx	155	5	associated	associate	VBN
cord-002808-84np9brx	155	6	L2	L2	NNP
cord-002808-84np9brx	155	7	appears	appear	VBZ
cord-002808-84np9brx	155	8	to	to	TO
cord-002808-84np9brx	155	9	be	be	VB
cord-002808-84np9brx	155	10	an	an	DT
cord-002808-84np9brx	155	11	inducible	inducible	JJ
cord-002808-84np9brx	155	12	transmembrane	transmembrane	NN
cord-002808-84np9brx	155	13	protein	protein	NN
cord-002808-84np9brx	155	14	,	,	,
cord-002808-84np9brx	155	15	with	with	IN
cord-002808-84np9brx	155	16	the	the	DT
cord-002808-84np9brx	155	17	ability	ability	NN
cord-002808-84np9brx	155	18	to	to	TO
cord-002808-84np9brx	155	19	insert	insert	VB
cord-002808-84np9brx	155	20	into	into	IN
cord-002808-84np9brx	155	21	membranes	membrane	NNS
cord-002808-84np9brx	155	22	and	and	CC
cord-002808-84np9brx	155	23	adopt	adopt	VB
cord-002808-84np9brx	155	24	a	a	DT
cord-002808-84np9brx	155	25	transmembrane	transmembrane	NN
cord-002808-84np9brx	155	26	configuration	configuration	NN
cord-002808-84np9brx	155	27	,	,	,
cord-002808-84np9brx	155	28	to	to	TO
cord-002808-84np9brx	155	29	drive	drive	VB
cord-002808-84np9brx	155	30	vDNA	vdna	RB
cord-002808-84np9brx	155	31	subcellular	subcellular	JJ
cord-002808-84np9brx	155	32	trafficking	trafficking	NN
cord-002808-84np9brx	155	33	by	by	IN
cord-002808-84np9brx	155	34	physically	physically	RB
cord-002808-84np9brx	155	35	linking	link	VBG
cord-002808-84np9brx	155	36	the	the	DT
cord-002808-84np9brx	155	37	lumenal	lumenal	NNP
cord-002808-84np9brx	155	38	vDNA	vdna	NN
cord-002808-84np9brx	155	39	to	to	TO
cord-002808-84np9brx	155	40	host	host	VB
cord-002808-84np9brx	155	41	cytosolic	cytosolic	JJ
cord-002808-84np9brx	155	42	sorting	sorting	NN
cord-002808-84np9brx	155	43	proteins	protein	NNS
cord-002808-84np9brx	155	44	(	(	-LRB-
cord-002808-84np9brx	155	45	Figure	figure	NN
cord-002808-84np9brx	155	46	2	2	CD
cord-002808-84np9brx	155	47	)	)	-RRB-
cord-002808-84np9brx	155	48	.	.	.
cord-002808-84np9brx	156	1	L2	L2	NNP
cord-002808-84np9brx	156	2	's	's	POS
cord-002808-84np9brx	156	3	function	function	NN
cord-002808-84np9brx	156	4	to	to	TO
cord-002808-84np9brx	156	5	facilitate	facilitate	VB
cord-002808-84np9brx	156	6	vDNA	vdna	DT
cord-002808-84np9brx	156	7	delivery	delivery	NN
cord-002808-84np9brx	156	8	across	across	IN
cord-002808-84np9brx	156	9	the	the	DT
cord-002808-84np9brx	156	10	limiting	limit	VBG
cord-002808-84np9brx	156	11	membrane	membrane	NN
cord-002808-84np9brx	156	12	is	be	VBZ
cord-002808-84np9brx	156	13	analogous	analogous	JJ
cord-002808-84np9brx	156	14	to	to	IN
cord-002808-84np9brx	156	15	that	that	DT
cord-002808-84np9brx	156	16	of	of	IN
cord-002808-84np9brx	156	17	many	many	JJ
cord-002808-84np9brx	156	18	bacterial	bacterial	JJ
cord-002808-84np9brx	156	19	toxins	toxin	NNS
cord-002808-84np9brx	156	20	,	,	,
cord-002808-84np9brx	156	21	which	which	WDT
cord-002808-84np9brx	156	22	penetrate	penetrate	VBP
cord-002808-84np9brx	156	23	intracellular	intracellular	JJ
cord-002808-84np9brx	156	24	membranes	membrane	NNS
cord-002808-84np9brx	156	25	and	and	CC
cord-002808-84np9brx	156	26	deliver	deliver	VBP
cord-002808-84np9brx	156	27	toxin	toxin	NN
cord-002808-84np9brx	156	28	domains	domain	NNS
cord-002808-84np9brx	156	29	to	to	IN
cord-002808-84np9brx	156	30	the	the	DT
cord-002808-84np9brx	156	31	cytosol	cytosol	NN
cord-002808-84np9brx	156	32	.	.	.
cord-002808-84np9brx	157	1	Many	many	JJ
cord-002808-84np9brx	157	2	of	of	IN
cord-002808-84np9brx	157	3	these	these	DT
cord-002808-84np9brx	157	4	bacterial	bacterial	JJ
cord-002808-84np9brx	157	5	toxins	toxin	NNS
cord-002808-84np9brx	157	6	including	include	VBG
cord-002808-84np9brx	157	7	diphtheria	diphtheria	NN
cord-002808-84np9brx	157	8	toxin	toxin	NN
cord-002808-84np9brx	157	9	,	,	,
cord-002808-84np9brx	157	10	anthrax	anthrax	NN
cord-002808-84np9brx	157	11	toxin	toxin	NN
cord-002808-84np9brx	157	12	protective	protective	JJ
cord-002808-84np9brx	157	13	antigen	antigen	NN
cord-002808-84np9brx	157	14	,	,	,
cord-002808-84np9brx	157	15	Shiga	Shiga	NNP
cord-002808-84np9brx	157	16	toxin	toxin	NN
cord-002808-84np9brx	157	17	,	,	,
cord-002808-84np9brx	157	18	and	and	CC
cord-002808-84np9brx	157	19	Pseudomonas	Pseudomonas	NNP
cord-002808-84np9brx	157	20	exotoxin	exotoxin	NN
cord-002808-84np9brx	158	1	A	a	DT
cord-002808-84np9brx	158	2	[	[	-LRB-
cord-002808-84np9brx	158	3	82	82	CD
cord-002808-84np9brx	158	4	,	,	,
cord-002808-84np9brx	158	5	83	83	CD
cord-002808-84np9brx	158	6	]	]	-RRB-
cord-002808-84np9brx	158	7	also	also	RB
cord-002808-84np9brx	158	8	rely	rely	VBP
cord-002808-84np9brx	158	9	on	on	IN
cord-002808-84np9brx	158	10	proteolytic	proteolytic	JJ
cord-002808-84np9brx	158	11	activation	activation	NN
cord-002808-84np9brx	158	12	by	by	IN
cord-002808-84np9brx	158	13	furin	furin	NN
cord-002808-84np9brx	158	14	and	and	CC
cord-002808-84np9brx	158	15	other	other	JJ
cord-002808-84np9brx	158	16	proteases	protease	NNS
cord-002808-84np9brx	158	17	to	to	TO
cord-002808-84np9brx	158	18	trigger	trigger	VB
cord-002808-84np9brx	158	19	conformational	conformational	JJ
cord-002808-84np9brx	158	20	changes	change	NNS
cord-002808-84np9brx	158	21	and	and	CC
cord-002808-84np9brx	158	22	structural	structural	JJ
cord-002808-84np9brx	158	23	rearrangements	rearrangement	NNS
cord-002808-84np9brx	158	24	that	that	WDT
cord-002808-84np9brx	158	25	underlie	underlie	VBP
cord-002808-84np9brx	158	26	toxin	toxin	NN
cord-002808-84np9brx	158	27	membrane	membrane	NN
cord-002808-84np9brx	158	28	insertion	insertion	NN
cord-002808-84np9brx	158	29	and	and	CC
cord-002808-84np9brx	158	30	penetration	penetration	NN
cord-002808-84np9brx	158	31	.	.	.
cord-002808-84np9brx	159	1	Given	give	VBN
cord-002808-84np9brx	159	2	the	the	DT
cord-002808-84np9brx	159	3	requirement	requirement	NN
cord-002808-84np9brx	159	4	for	for	IN
cord-002808-84np9brx	159	5	furin	furin	NN
cord-002808-84np9brx	159	6	in	in	IN
cord-002808-84np9brx	159	7	TGN	TGN	NNP
cord-002808-84np9brx	159	8	localization	localization	NN
cord-002808-84np9brx	159	9	of	of	IN
cord-002808-84np9brx	159	10	L2	L2	NNP
cord-002808-84np9brx	159	11	/	/	SYM
cord-002808-84np9brx	159	12	vDNA	vdna	UH
cord-002808-84np9brx	159	13	,	,	,
cord-002808-84np9brx	159	14	it	-PRON-	PRP
cord-002808-84np9brx	159	15	is	be	VBZ
cord-002808-84np9brx	159	16	very	very	RB
cord-002808-84np9brx	159	17	likely	likely	JJ
cord-002808-84np9brx	159	18	that	that	IN
cord-002808-84np9brx	159	19	cleavage	cleavage	NN
cord-002808-84np9brx	159	20	triggers	trigger	VBZ
cord-002808-84np9brx	159	21	a	a	DT
cord-002808-84np9brx	159	22	structural	structural	JJ
cord-002808-84np9brx	159	23	change	change	NN
cord-002808-84np9brx	159	24	that	that	WDT
cord-002808-84np9brx	159	25	enables	enable	VBZ
cord-002808-84np9brx	159	26	L2	L2	NNP
cord-002808-84np9brx	159	27	to	to	TO
cord-002808-84np9brx	159	28	insert	insert	VB
cord-002808-84np9brx	159	29	and	and	CC
cord-002808-84np9brx	159	30	protrude	protrude	VB
cord-002808-84np9brx	159	31	into	into	IN
cord-002808-84np9brx	159	32	the	the	DT
cord-002808-84np9brx	159	33	local	local	JJ
cord-002808-84np9brx	159	34	membrane	membrane	NN
cord-002808-84np9brx	159	35	via	via	IN
cord-002808-84np9brx	159	36	the	the	DT
cord-002808-84np9brx	159	37	TMD	TMD	NNP
cord-002808-84np9brx	159	38	to	to	TO
cord-002808-84np9brx	159	39	recruit	recruit	VB
cord-002808-84np9brx	159	40	cytosolic	cytosolic	JJ
cord-002808-84np9brx	159	41	SNXs	snx	NNS
cord-002808-84np9brx	159	42	and	and	CC
cord-002808-84np9brx	159	43	retromer	retromer	NN
cord-002808-84np9brx	159	44	.	.	.
cord-002808-84np9brx	160	1	Until	until	IN
cord-002808-84np9brx	160	2	structural	structural	JJ
cord-002808-84np9brx	160	3	data	datum	NNS
cord-002808-84np9brx	160	4	on	on	IN
cord-002808-84np9brx	160	5	L2	L2	NNP
cord-002808-84np9brx	160	6	is	be	VBZ
cord-002808-84np9brx	160	7	obtained	obtain	VBN
cord-002808-84np9brx	160	8	,	,	,
cord-002808-84np9brx	160	9	the	the	DT
cord-002808-84np9brx	160	10	nature	nature	NN
cord-002808-84np9brx	160	11	of	of	IN
cord-002808-84np9brx	160	12	any	any	DT
cord-002808-84np9brx	160	13	cleavage	cleavage	NN
cord-002808-84np9brx	160	14	-	-	HYPH
cord-002808-84np9brx	160	15	induced	induce	VBN
cord-002808-84np9brx	160	16	conformational	conformational	JJ
cord-002808-84np9brx	160	17	changes	change	NNS
cord-002808-84np9brx	160	18	will	will	MD
cord-002808-84np9brx	160	19	remain	remain	VB
cord-002808-84np9brx	160	20	elusive	elusive	JJ
cord-002808-84np9brx	160	21	.	.	.
cord-002808-84np9brx	161	1	Although	although	IN
cord-002808-84np9brx	161	2	direct	direct	JJ
cord-002808-84np9brx	161	3	evidence	evidence	NN
cord-002808-84np9brx	161	4	is	be	VBZ
cord-002808-84np9brx	161	5	lacking	lack	VBG
cord-002808-84np9brx	161	6	,	,	,
cord-002808-84np9brx	161	7	the	the	DT
cord-002808-84np9brx	161	8	TMD	TMD	NNP
cord-002808-84np9brx	161	9	itself	-PRON-	PRP
cord-002808-84np9brx	161	10	may	may	MD
cord-002808-84np9brx	161	11	play	play	VB
cord-002808-84np9brx	161	12	a	a	DT
cord-002808-84np9brx	161	13	role	role	NN
cord-002808-84np9brx	161	14	in	in	IN
cord-002808-84np9brx	161	15	the	the	DT
cord-002808-84np9brx	161	16	initial	initial	JJ
cord-002808-84np9brx	161	17	insertion	insertion	NN
cord-002808-84np9brx	161	18	of	of	IN
cord-002808-84np9brx	161	19	L2	l2	NN
cord-002808-84np9brx	161	20	into	into	IN
cord-002808-84np9brx	161	21	membranes	membrane	NNS
cord-002808-84np9brx	161	22	.	.	.
cord-002808-84np9brx	162	1	It	-PRON-	PRP
cord-002808-84np9brx	162	2	is	be	VBZ
cord-002808-84np9brx	162	3	noteworthy	noteworthy	JJ
cord-002808-84np9brx	162	4	that	that	IN
cord-002808-84np9brx	162	5	the	the	DT
cord-002808-84np9brx	162	6	L2	L2	NNP
cord-002808-84np9brx	162	7	TMD	TMD	NNP
cord-002808-84np9brx	162	8	is	be	VBZ
cord-002808-84np9brx	162	9	quite	quite	RB
cord-002808-84np9brx	162	10	similar	similar	JJ
cord-002808-84np9brx	162	11	to	to	IN
cord-002808-84np9brx	162	12	the	the	DT
cord-002808-84np9brx	162	13	fusion	fusion	NN
cord-002808-84np9brx	162	14	peptides	peptide	NNS
cord-002808-84np9brx	162	15	(	(	-LRB-
cord-002808-84np9brx	162	16	FPs	FPs	NNP
cord-002808-84np9brx	162	17	)	)	-RRB-
cord-002808-84np9brx	162	18	from	from	IN
cord-002808-84np9brx	162	19	many	many	JJ
cord-002808-84np9brx	162	20	type	type	NN
cord-002808-84np9brx	162	21	-	-	:
cord-002808-84np9brx	162	22	I	-PRON-	PRP
cord-002808-84np9brx	162	23	fusogenic	fusogenic	JJ
cord-002808-84np9brx	162	24	glycoproteins	glycoprotein	NNS
cord-002808-84np9brx	162	25	of	of	IN
cord-002808-84np9brx	162	26	enveloped	envelop	VBN
cord-002808-84np9brx	162	27	viruses	virus	NNS
cord-002808-84np9brx	162	28	of	of	IN
cord-002808-84np9brx	162	29	the	the	DT
cord-002808-84np9brx	162	30	Orthomyxoviridae	Orthomyxoviridae	NNP
cord-002808-84np9brx	162	31	,	,	,
cord-002808-84np9brx	162	32	Paramyxoviridae	Paramyxoviridae	NNP
cord-002808-84np9brx	162	33	,	,	,
cord-002808-84np9brx	162	34	and	and	CC
cord-002808-84np9brx	162	35	Retroviridae	Retroviridae	NNP
cord-002808-84np9brx	162	36	families	family	NNS
cord-002808-84np9brx	162	37	[	[	-LRB-
cord-002808-84np9brx	162	38	79	79	CD
cord-002808-84np9brx	162	39	]	]	-RRB-
cord-002808-84np9brx	162	40	.	.	.
cord-002808-84np9brx	163	1	These	these	DT
cord-002808-84np9brx	163	2	fusion	fusion	NN
cord-002808-84np9brx	163	3	peptides	peptide	NNS
cord-002808-84np9brx	163	4	generally	generally	RB
cord-002808-84np9brx	163	5	consist	consist	VBP
cord-002808-84np9brx	163	6	of~20	of~20	NNP
cord-002808-84np9brx	163	7	apolar	apolar	JJ
cord-002808-84np9brx	163	8	residues	residue	NNS
cord-002808-84np9brx	163	9	,	,	,
cord-002808-84np9brx	163	10	and	and	CC
cord-002808-84np9brx	163	11	are	be	VBP
cord-002808-84np9brx	163	12	typically	typically	RB
cord-002808-84np9brx	163	13	enriched	enrich	VBN
cord-002808-84np9brx	163	14	for	for	IN
cord-002808-84np9brx	163	15	glycine	glycine	NN
cord-002808-84np9brx	163	16	,	,	,
cord-002808-84np9brx	163	17	a	a	DT
cord-002808-84np9brx	163	18	composition	composition	NN
cord-002808-84np9brx	163	19	believed	believe	VBN
cord-002808-84np9brx	163	20	to	to	TO
cord-002808-84np9brx	163	21	impart	impart	VB
cord-002808-84np9brx	163	22	conformational	conformational	JJ
cord-002808-84np9brx	163	23	flexibility	flexibility	NN
cord-002808-84np9brx	163	24	.	.	.
cord-002808-84np9brx	164	1	The	the	DT
cord-002808-84np9brx	164	2	structurally	structurally	RB
cord-002808-84np9brx	164	3	dynamic	dynamic	JJ
cord-002808-84np9brx	164	4	nature	nature	NN
cord-002808-84np9brx	164	5	of	of	IN
cord-002808-84np9brx	164	6	these	these	DT
cord-002808-84np9brx	164	7	fusion	fusion	NN
cord-002808-84np9brx	164	8	peptides	peptide	NNS
cord-002808-84np9brx	164	9	is	be	VBZ
cord-002808-84np9brx	164	10	thought	think	VBN
cord-002808-84np9brx	164	11	to	to	TO
cord-002808-84np9brx	164	12	be	be	VB
cord-002808-84np9brx	164	13	critical	critical	JJ
cord-002808-84np9brx	164	14	for	for	IN
cord-002808-84np9brx	164	15	their	-PRON-	PRP$
cord-002808-84np9brx	164	16	ability	ability	NN
cord-002808-84np9brx	164	17	to	to	TO
cord-002808-84np9brx	164	18	partition	partition	VB
cord-002808-84np9brx	164	19	into	into	IN
cord-002808-84np9brx	164	20	and	and	CC
cord-002808-84np9brx	164	21	destabilize	destabilize	VB
cord-002808-84np9brx	164	22	local	local	JJ
cord-002808-84np9brx	164	23	membranes	membrane	NNS
cord-002808-84np9brx	164	24	[	[	-LRB-
cord-002808-84np9brx	164	25	84	84	CD
cord-002808-84np9brx	164	26	]	]	-RRB-
cord-002808-84np9brx	164	27	[	[	-LRB-
cord-002808-84np9brx	164	28	85	85	CD
cord-002808-84np9brx	164	29	]	]	-RRB-
cord-002808-84np9brx	164	30	[	[	-LRB-
cord-002808-84np9brx	164	31	86	86	CD
cord-002808-84np9brx	164	32	]	]	-RRB-
cord-002808-84np9brx	165	1	[	[	-LRB-
cord-002808-84np9brx	165	2	87	87	CD
cord-002808-84np9brx	165	3	]	]	-RRB-
cord-002808-84np9brx	165	4	.	.	.
cord-002808-84np9brx	166	1	It	-PRON-	PRP
cord-002808-84np9brx	166	2	is	be	VBZ
cord-002808-84np9brx	166	3	also	also	RB
cord-002808-84np9brx	166	4	noteworthy	noteworthy	JJ
cord-002808-84np9brx	166	5	that	that	IN
cord-002808-84np9brx	166	6	,	,	,
cord-002808-84np9brx	166	7	like	like	IN
cord-002808-84np9brx	166	8	L2	L2	NNP
cord-002808-84np9brx	166	9	,	,	,
cord-002808-84np9brx	166	10	these	these	DT
cord-002808-84np9brx	166	11	viral	viral	JJ
cord-002808-84np9brx	166	12	fusion	fusion	NN
cord-002808-84np9brx	166	13	proteins	protein	NNS
cord-002808-84np9brx	166	14	require	require	VBP
cord-002808-84np9brx	166	15	"	"	``
cord-002808-84np9brx	166	16	priming	priming	NN
cord-002808-84np9brx	166	17	"	"	''
cord-002808-84np9brx	166	18	by	by	IN
cord-002808-84np9brx	166	19	proteolytic	proteolytic	JJ
cord-002808-84np9brx	166	20	cleavage	cleavage	NN
cord-002808-84np9brx	166	21	and	and	CC
cord-002808-84np9brx	166	22	"	"	``
cord-002808-84np9brx	166	23	activation	activation	NN
cord-002808-84np9brx	166	24	"	"	''
cord-002808-84np9brx	166	25	by	by	IN
cord-002808-84np9brx	166	26	environmental	environmental	JJ
cord-002808-84np9brx	166	27	cues	cue	NNS
cord-002808-84np9brx	166	28	like	like	IN
cord-002808-84np9brx	166	29	low	low	JJ
cord-002808-84np9brx	166	30	pH	ph	NN
cord-002808-84np9brx	166	31	or	or	CC
cord-002808-84np9brx	166	32	receptor	receptor	NN
cord-002808-84np9brx	166	33	binding	bind	VBG
cord-002808-84np9brx	166	34	[	[	-LRB-
cord-002808-84np9brx	166	35	88	88	CD
cord-002808-84np9brx	166	36	]	]	-RRB-
cord-002808-84np9brx	166	37	.	.	.
cord-002808-84np9brx	167	1	It	-PRON-	PRP
cord-002808-84np9brx	167	2	is	be	VBZ
cord-002808-84np9brx	167	3	conceptually	conceptually	RB
cord-002808-84np9brx	167	4	challenging	challenging	JJ
cord-002808-84np9brx	167	5	to	to	TO
cord-002808-84np9brx	167	6	envision	envision	VB
cord-002808-84np9brx	167	7	how	how	WRB
cord-002808-84np9brx	167	8	L2	L2	NNP
cord-002808-84np9brx	167	9	could	could	MD
cord-002808-84np9brx	167	10	achieve	achieve	VB
cord-002808-84np9brx	167	11	a	a	DT
cord-002808-84np9brx	167	12	type	type	NN
cord-002808-84np9brx	167	13	-	-	:
cord-002808-84np9brx	167	14	I	i	NN
cord-002808-84np9brx	167	15	transmembrane	transmembrane	NN
cord-002808-84np9brx	167	16	state	state	NN
cord-002808-84np9brx	167	17	upon	upon	IN
cord-002808-84np9brx	167	18	insertion	insertion	NN
cord-002808-84np9brx	167	19	of	of	IN
cord-002808-84np9brx	167	20	its	-PRON-	PRP$
cord-002808-84np9brx	167	21	N	n	CD
cord-002808-84np9brx	167	22	-	-	HYPH
cord-002808-84np9brx	167	23	terminal	terminal	NN
cord-002808-84np9brx	167	24	TMD	TMD	NNP
cord-002808-84np9brx	167	25	-	-	HYPH
cord-002808-84np9brx	167	26	L2	L2	NNP
cord-002808-84np9brx	167	27	would	would	MD
cord-002808-84np9brx	167	28	have	have	VB
cord-002808-84np9brx	167	29	to	to	TO
cord-002808-84np9brx	167	30	essentially	essentially	RB
cord-002808-84np9brx	167	31	drag	drag	VB
cord-002808-84np9brx	167	32	400	400	CD
cord-002808-84np9brx	167	33	residues	residue	NNS
cord-002808-84np9brx	167	34	C	c	NN
cord-002808-84np9brx	167	35	-	-	HYPH
cord-002808-84np9brx	167	36	terminal	terminal	NN
cord-002808-84np9brx	167	37	to	to	IN
cord-002808-84np9brx	167	38	the	the	DT
cord-002808-84np9brx	167	39	TMD	TMD	NNP
cord-002808-84np9brx	167	40	across	across	IN
cord-002808-84np9brx	167	41	the	the	DT
cord-002808-84np9brx	167	42	membrane	membrane	NN
cord-002808-84np9brx	167	43	.	.	.
cord-002808-84np9brx	168	1	Perhaps	perhaps	RB
cord-002808-84np9brx	168	2	cooperative	cooperative	JJ
cord-002808-84np9brx	168	3	interactions	interaction	NNS
cord-002808-84np9brx	168	4	between	between	IN
cord-002808-84np9brx	168	5	the	the	DT
cord-002808-84np9brx	168	6	TMD	TMD	NNP
cord-002808-84np9brx	168	7	,	,	,
cord-002808-84np9brx	168	8	the	the	DT
cord-002808-84np9brx	168	9	C	c	NN
cord-002808-84np9brx	168	10	-	-	HYPH
cord-002808-84np9brx	168	11	terminal	terminal	NN
cord-002808-84np9brx	168	12	membrane	membrane	NN
cord-002808-84np9brx	168	13	disruption	disruption	NN
cord-002808-84np9brx	168	14	peptide	peptide	NN
cord-002808-84np9brx	168	15	,	,	,
cord-002808-84np9brx	168	16	and	and	CC
cord-002808-84np9brx	168	17	the	the	DT
cord-002808-84np9brx	168	18	membrane	membrane	NN
cord-002808-84np9brx	168	19	are	be	VBP
cord-002808-84np9brx	168	20	required	require	VBN
cord-002808-84np9brx	168	21	for	for	IN
cord-002808-84np9brx	168	22	insertion	insertion	NN
cord-002808-84np9brx	168	23	and	and	CC
cord-002808-84np9brx	168	24	protrusion	protrusion	NN
cord-002808-84np9brx	168	25	of	of	IN
cord-002808-84np9brx	168	26	L2	l2	NN
cord-002808-84np9brx	168	27	.	.	.
cord-002808-84np9brx	169	1	How	how	WRB
cord-002808-84np9brx	169	2	does	do	VBZ
cord-002808-84np9brx	169	3	γ	γ	NN
cord-002808-84np9brx	169	4	-	-	HYPH
cord-002808-84np9brx	169	5	sec	sec	NNP
cord-002808-84np9brx	169	6	facilitate	facilitate	VB
cord-002808-84np9brx	169	7	L2	L2	NNP
cord-002808-84np9brx	169	8	/	/	,
cord-002808-84np9brx	169	9	vDNA	vdna	NN
cord-002808-84np9brx	169	10	trafficking	trafficking	NN
cord-002808-84np9brx	169	11	?	?	.
cord-002808-84np9brx	170	1	No	no	DT
cord-002808-84np9brx	170	2	interaction	interaction	NN
cord-002808-84np9brx	170	3	between	between	IN
cord-002808-84np9brx	170	4	L2	L2	NNP
cord-002808-84np9brx	170	5	and	and	CC
cord-002808-84np9brx	170	6	the	the	DT
cord-002808-84np9brx	170	7	γ	γ	NNP
cord-002808-84np9brx	170	8	-	-	HYPH
cord-002808-84np9brx	170	9	sec	sec	NNP
cord-002808-84np9brx	170	10	complex	complex	NN
cord-002808-84np9brx	170	11	has	have	VBZ
cord-002808-84np9brx	170	12	been	be	VBN
cord-002808-84np9brx	170	13	reported	report	VBN
cord-002808-84np9brx	170	14	,	,	,
cord-002808-84np9brx	170	15	although	although	IN
cord-002808-84np9brx	170	16	it	-PRON-	PRP
cord-002808-84np9brx	170	17	is	be	VBZ
cord-002808-84np9brx	170	18	tempting	tempt	VBG
cord-002808-84np9brx	170	19	to	to	TO
cord-002808-84np9brx	170	20	envision	envision	VB
cord-002808-84np9brx	170	21	that	that	IN
cord-002808-84np9brx	170	22	L2	L2	NNP
cord-002808-84np9brx	170	23	could	could	MD
cord-002808-84np9brx	170	24	interact	interact	VB
cord-002808-84np9brx	170	25	with	with	IN
cord-002808-84np9brx	170	26	the	the	DT
cord-002808-84np9brx	170	27	complex	complex	NN
cord-002808-84np9brx	170	28	via	via	IN
cord-002808-84np9brx	170	29	its	-PRON-	PRP$
cord-002808-84np9brx	170	30	TMD	TMD	NNP
cord-002808-84np9brx	170	31	while	while	IN
cord-002808-84np9brx	170	32	protruding	protrude	VBG
cord-002808-84np9brx	170	33	through	through	IN
cord-002808-84np9brx	170	34	the	the	DT
cord-002808-84np9brx	170	35	membrane	membrane	NN
cord-002808-84np9brx	170	36	.	.	.
cord-002808-84np9brx	171	1	Alternatively	alternatively	RB
cord-002808-84np9brx	171	2	,	,	,
cord-002808-84np9brx	171	3	γ	γ	NN
cord-002808-84np9brx	171	4	-	-	HYPH
cord-002808-84np9brx	171	5	sec	sec	NNP
cord-002808-84np9brx	171	6	activity	activity	NN
cord-002808-84np9brx	171	7	could	could	MD
cord-002808-84np9brx	171	8	somehow	somehow	RB
cord-002808-84np9brx	171	9	be	be	VB
cord-002808-84np9brx	171	10	required	require	VBN
cord-002808-84np9brx	171	11	for	for	IN
cord-002808-84np9brx	171	12	L2	l2	NN
cord-002808-84np9brx	171	13	to	to	TO
cord-002808-84np9brx	171	14	initially	initially	RB
cord-002808-84np9brx	171	15	insert	insert	VB
cord-002808-84np9brx	171	16	into	into	IN
cord-002808-84np9brx	171	17	membranes	membrane	NNS
cord-002808-84np9brx	171	18	to	to	TO
cord-002808-84np9brx	171	19	achieve	achieve	VB
cord-002808-84np9brx	171	20	membrane	membrane	NN
cord-002808-84np9brx	171	21	protrusion	protrusion	NN
cord-002808-84np9brx	171	22	.	.	.
cord-002808-84np9brx	172	1	This	this	DT
cord-002808-84np9brx	172	2	latter	latter	JJ
cord-002808-84np9brx	172	3	possibility	possibility	NN
cord-002808-84np9brx	172	4	would	would	MD
cord-002808-84np9brx	172	5	be	be	VB
cord-002808-84np9brx	172	6	consistent	consistent	JJ
cord-002808-84np9brx	172	7	with	with	IN
cord-002808-84np9brx	172	8	the	the	DT
cord-002808-84np9brx	172	9	trafficking	traffic	VBG
cord-002808-84np9brx	172	10	defects	defect	NNS
cord-002808-84np9brx	172	11	observed	observe	VBN
cord-002808-84np9brx	172	12	upon	upon	IN
cord-002808-84np9brx	172	13	inhibition	inhibition	NN
cord-002808-84np9brx	172	14	of	of	IN
cord-002808-84np9brx	172	15	gamma	gamma	NNP
cord-002808-84np9brx	172	16	secretase	secretase	NNP
cord-002808-84np9brx	172	17	[	[	-LRB-
cord-002808-84np9brx	172	18	48	48	CD
cord-002808-84np9brx	172	19	]	]	-RRB-
cord-002808-84np9brx	172	20	,	,	,
cord-002808-84np9brx	172	21	as	as	IN
cord-002808-84np9brx	172	22	failure	failure	NN
cord-002808-84np9brx	172	23	to	to	TO
cord-002808-84np9brx	172	24	insert	insert	VB
cord-002808-84np9brx	172	25	and	and	CC
cord-002808-84np9brx	172	26	protrude	protrude	VB
cord-002808-84np9brx	172	27	through	through	IN
cord-002808-84np9brx	172	28	the	the	DT
cord-002808-84np9brx	172	29	membrane	membrane	NN
cord-002808-84np9brx	172	30	would	would	MD
cord-002808-84np9brx	172	31	be	be	VB
cord-002808-84np9brx	172	32	expected	expect	VBN
cord-002808-84np9brx	172	33	to	to	TO
cord-002808-84np9brx	172	34	block	block	VB
cord-002808-84np9brx	172	35	TGN	TGN	NNP
cord-002808-84np9brx	172	36	localization	localization	NN
cord-002808-84np9brx	172	37	,	,	,
cord-002808-84np9brx	172	38	and	and	CC
cord-002808-84np9brx	172	39	may	may	MD
cord-002808-84np9brx	172	40	instead	instead	RB
cord-002808-84np9brx	172	41	cause	cause	VB
cord-002808-84np9brx	172	42	trafficking	traffic	VBG
cord-002808-84np9brx	172	43	away	away	RB
cord-002808-84np9brx	172	44	from	from	IN
cord-002808-84np9brx	172	45	EEA1	EEA1	NNP
cord-002808-84np9brx	172	46	positive	positive	JJ
cord-002808-84np9brx	172	47	early	early	JJ
cord-002808-84np9brx	172	48	endosomes	endosome	NNS
cord-002808-84np9brx	172	49	into	into	IN
cord-002808-84np9brx	172	50	a	a	DT
cord-002808-84np9brx	172	51	degradative	degradative	JJ
cord-002808-84np9brx	172	52	lysosomal	lysosomal	JJ
cord-002808-84np9brx	172	53	pathway	pathway	NN
cord-002808-84np9brx	172	54	.	.	.
cord-002808-84np9brx	173	1	Although	although	IN
cord-002808-84np9brx	173	2	no	no	DT
cord-002808-84np9brx	173	3	evidence	evidence	NN
cord-002808-84np9brx	173	4	exists	exist	VBZ
cord-002808-84np9brx	173	5	supporting	support	VBG
cord-002808-84np9brx	173	6	a	a	DT
cord-002808-84np9brx	173	7	role	role	NN
cord-002808-84np9brx	173	8	for	for	IN
cord-002808-84np9brx	173	9	γ	γ	NNP
cord-002808-84np9brx	173	10	-	-	HYPH
cord-002808-84np9brx	173	11	sec	sec	NNP
cord-002808-84np9brx	173	12	in	in	IN
cord-002808-84np9brx	173	13	HPV	HPV	NNP
cord-002808-84np9brx	173	14	endocytosis	endocytosis	NN
cord-002808-84np9brx	173	15	,	,	,
cord-002808-84np9brx	173	16	it	-PRON-	PRP
cord-002808-84np9brx	173	17	has	have	VBZ
cord-002808-84np9brx	173	18	been	be	VBN
cord-002808-84np9brx	173	19	found	find	VBN
cord-002808-84np9brx	173	20	as	as	IN
cord-002808-84np9brx	173	21	part	part	NN
cord-002808-84np9brx	173	22	of	of	IN
cord-002808-84np9brx	173	23	a	a	DT
cord-002808-84np9brx	173	24	"	"	``
cord-002808-84np9brx	173	25	tetraspanin	tetraspanin	NNP
cord-002808-84np9brx	173	26	interactome	interactome	NNP
cord-002808-84np9brx	173	27	"	"	''
cord-002808-84np9brx	173	28	,	,	,
cord-002808-84np9brx	173	29	associated	associate	VBN
cord-002808-84np9brx	173	30	with	with	IN
cord-002808-84np9brx	173	31	many	many	JJ
cord-002808-84np9brx	173	32	of	of	IN
cord-002808-84np9brx	173	33	the	the	DT
cord-002808-84np9brx	173	34	same	same	JJ
cord-002808-84np9brx	173	35	molecules	molecule	NNS
cord-002808-84np9brx	173	36	believed	believe	VBN
cord-002808-84np9brx	173	37	to	to	TO
cord-002808-84np9brx	173	38	be	be	VB
cord-002808-84np9brx	173	39	part	part	NN
cord-002808-84np9brx	173	40	of	of	IN
cord-002808-84np9brx	173	41	the	the	DT
cord-002808-84np9brx	173	42	initial	initial	JJ
cord-002808-84np9brx	173	43	entry	entry	NN
cord-002808-84np9brx	173	44	receptor	receptor	NN
cord-002808-84np9brx	173	45	complex	complex	NN
cord-002808-84np9brx	173	46	,	,	,
cord-002808-84np9brx	173	47	including	include	VBG
cord-002808-84np9brx	173	48	tetraspanins	tetraspanins	NNP
cord-002808-84np9brx	173	49	CD9	CD9	NNP
cord-002808-84np9brx	173	50	and	and	CC
cord-002808-84np9brx	173	51	CD81	CD81	NNP
cord-002808-84np9brx	173	52	,	,	,
cord-002808-84np9brx	173	53	integrins	integrin	NNS
cord-002808-84np9brx	173	54	α3	α3	NN
cord-002808-84np9brx	173	55	and	and	CC
cord-002808-84np9brx	173	56	β1	β1	NNP
cord-002808-84np9brx	173	57	,	,	,
cord-002808-84np9brx	173	58	and	and	CC
cord-002808-84np9brx	173	59	annexin	annexin	NN
cord-002808-84np9brx	173	60	-	-	HYPH
cord-002808-84np9brx	173	61	A2	A2	NNP
cord-002808-84np9brx	173	62	[	[	-LRB-
cord-002808-84np9brx	173	63	89	89	CD
cord-002808-84np9brx	173	64	]	]	-RRB-
cord-002808-84np9brx	173	65	.	.	.
cord-002808-84np9brx	174	1	The	the	DT
cord-002808-84np9brx	174	2	γ	γ	NN
cord-002808-84np9brx	174	3	-	-	HYPH
cord-002808-84np9brx	174	4	sec	sec	NNP
cord-002808-84np9brx	174	5	complex	complex	NN
cord-002808-84np9brx	174	6	may	may	MD
cord-002808-84np9brx	174	7	therefore	therefore	RB
cord-002808-84np9brx	174	8	be	be	VB
cord-002808-84np9brx	174	9	present	present	JJ
cord-002808-84np9brx	174	10	locally	locally	RB
cord-002808-84np9brx	174	11	during	during	IN
cord-002808-84np9brx	174	12	uncoating	uncoating	NN
cord-002808-84np9brx	174	13	when	when	WRB
cord-002808-84np9brx	174	14	L2	L2	NNP
cord-002808-84np9brx	174	15	presumably	presumably	RB
cord-002808-84np9brx	174	16	adopts	adopt	VBZ
cord-002808-84np9brx	174	17	the	the	DT
cord-002808-84np9brx	174	18	protruding	protrude	VBG
cord-002808-84np9brx	174	19	conformation	conformation	NN
cord-002808-84np9brx	174	20	(	(	-LRB-
cord-002808-84np9brx	174	21	Figure	figure	NN
cord-002808-84np9brx	174	22	2	2	CD
cord-002808-84np9brx	174	23	)	)	-RRB-
cord-002808-84np9brx	174	24	.	.	.
cord-002808-84np9brx	175	1	In	in	IN
cord-002808-84np9brx	175	2	this	this	DT
cord-002808-84np9brx	175	3	scenario	scenario	NN
cord-002808-84np9brx	175	4	,	,	,
cord-002808-84np9brx	175	5	one	one	PRP
cord-002808-84np9brx	175	6	could	could	MD
cord-002808-84np9brx	175	7	also	also	RB
cord-002808-84np9brx	175	8	imagine	imagine	VB
cord-002808-84np9brx	175	9	L2	L2	NNP
cord-002808-84np9brx	175	10	actually	actually	RB
cord-002808-84np9brx	175	11	being	be	VBG
cord-002808-84np9brx	175	12	a	a	DT
cord-002808-84np9brx	175	13	substrate	substrate	NN
cord-002808-84np9brx	175	14	for	for	IN
cord-002808-84np9brx	175	15	γ	γ	NN
cord-002808-84np9brx	175	16	-	-	HYPH
cord-002808-84np9brx	175	17	sec	sec	NNP
cord-002808-84np9brx	175	18	cleavage	cleavage	NN
cord-002808-84np9brx	175	19	,	,	,
cord-002808-84np9brx	175	20	triggering	trigger	VBG
cord-002808-84np9brx	175	21	a	a	DT
cord-002808-84np9brx	175	22	conformational	conformational	JJ
cord-002808-84np9brx	175	23	change	change	NN
cord-002808-84np9brx	175	24	of	of	IN
cord-002808-84np9brx	175	25	some	some	DT
cord-002808-84np9brx	175	26	kind	kind	NN
cord-002808-84np9brx	175	27	upon	upon	IN
cord-002808-84np9brx	175	28	cleavage	cleavage	NN
cord-002808-84np9brx	175	29	of	of	IN
cord-002808-84np9brx	175	30	the	the	DT
cord-002808-84np9brx	175	31	L2	L2	NNP
cord-002808-84np9brx	175	32	TMD	TMD	NNP
cord-002808-84np9brx	175	33	.	.	.
cord-002808-84np9brx	176	1	While	while	IN
cord-002808-84np9brx	176	2	attractive	attractive	JJ
cord-002808-84np9brx	176	3	,	,	,
cord-002808-84np9brx	176	4	there	there	EX
cord-002808-84np9brx	176	5	is	be	VBZ
cord-002808-84np9brx	176	6	no	no	DT
cord-002808-84np9brx	176	7	published	publish	VBN
cord-002808-84np9brx	176	8	evidence	evidence	NN
cord-002808-84np9brx	176	9	supporting	support	VBG
cord-002808-84np9brx	176	10	this	this	DT
cord-002808-84np9brx	176	11	notion	notion	NN
cord-002808-84np9brx	176	12	.	.	.
cord-002808-84np9brx	177	1	This	this	DT
cord-002808-84np9brx	177	2	begs	beg	VBZ
cord-002808-84np9brx	177	3	the	the	DT
cord-002808-84np9brx	177	4	question	question	NN
cord-002808-84np9brx	177	5	-	-	:
cord-002808-84np9brx	177	6	if	if	IN
cord-002808-84np9brx	177	7	L2	L2	NNP
cord-002808-84np9brx	177	8	is	be	VBZ
cord-002808-84np9brx	177	9	not	not	RB
cord-002808-84np9brx	177	10	a	a	DT
cord-002808-84np9brx	177	11	substrate	substrate	NN
cord-002808-84np9brx	177	12	for	for	IN
cord-002808-84np9brx	177	13	γ	γ	NN
cord-002808-84np9brx	177	14	-	-	HYPH
cord-002808-84np9brx	177	15	sec	sec	NNP
cord-002808-84np9brx	177	16	then	then	RB
cord-002808-84np9brx	178	1	how	how	WRB
cord-002808-84np9brx	178	2	does	do	VBZ
cord-002808-84np9brx	178	3	inhibition	inhibition	NN
cord-002808-84np9brx	178	4	of	of	IN
cord-002808-84np9brx	178	5	γ	γ	NNP
cord-002808-84np9brx	178	6	-	-	HYPH
cord-002808-84np9brx	178	7	sec	sec	NNP
cord-002808-84np9brx	178	8	catalysis	catalysis	NN
cord-002808-84np9brx	178	9	affect	affect	VBP
cord-002808-84np9brx	178	10	L2	L2	NNP
cord-002808-84np9brx	178	11	/	/	,
cord-002808-84np9brx	178	12	vDNA	vdna	NN
cord-002808-84np9brx	178	13	trafficking	trafficking	NN
cord-002808-84np9brx	178	14	so	so	RB
cord-002808-84np9brx	178	15	drastically	drastically	RB
cord-002808-84np9brx	178	16	?	?	.
cord-002808-84np9brx	179	1	Perhaps	perhaps	RB
cord-002808-84np9brx	179	2	γ	γ	NN
cord-002808-84np9brx	179	3	-	-	HYPH
cord-002808-84np9brx	179	4	sec	sec	JJ
cord-002808-84np9brx	179	5	cleavage	cleavage	NN
cord-002808-84np9brx	179	6	of	of	IN
cord-002808-84np9brx	179	7	a	a	DT
cord-002808-84np9brx	179	8	cellular	cellular	JJ
cord-002808-84np9brx	179	9	protein	protein	NN
cord-002808-84np9brx	179	10	somehow	somehow	RB
cord-002808-84np9brx	179	11	modulates	modulate	VBZ
cord-002808-84np9brx	179	12	trafficking	trafficking	NN
cord-002808-84np9brx	179	13	,	,	,
cord-002808-84np9brx	179	14	or	or	CC
cord-002808-84np9brx	179	15	L2	L2	NNP
cord-002808-84np9brx	179	16	may	may	MD
cord-002808-84np9brx	179	17	actually	actually	RB
cord-002808-84np9brx	179	18	be	be	VB
cord-002808-84np9brx	179	19	a	a	DT
cord-002808-84np9brx	179	20	"	"	``
cord-002808-84np9brx	179	21	pseudosubstrate	pseudosubstrate	JJ
cord-002808-84np9brx	179	22	"	"	''
cord-002808-84np9brx	179	23	,	,	,
cord-002808-84np9brx	179	24	interacting	interact	VBG
cord-002808-84np9brx	179	25	with	with	IN
cord-002808-84np9brx	179	26	γ	γ	NNP
cord-002808-84np9brx	179	27	-	-	HYPH
cord-002808-84np9brx	179	28	sec	sec	NNP
cord-002808-84np9brx	179	29	without	without	IN
cord-002808-84np9brx	179	30	cleavage	cleavage	NN
cord-002808-84np9brx	179	31	.	.	.
cord-002808-84np9brx	180	1	TMD	TMD	NNP
cord-002808-84np9brx	180	2	substrates	substrate	NNS
cord-002808-84np9brx	180	3	of	of	IN
cord-002808-84np9brx	180	4	γ	γ	NNP
cord-002808-84np9brx	180	5	-	-	HYPH
cord-002808-84np9brx	180	6	sec	sec	NNP
cord-002808-84np9brx	180	7	are	be	VBP
cord-002808-84np9brx	180	8	believed	believe	VBN
cord-002808-84np9brx	180	9	to	to	IN
cord-002808-84np9brx	180	10	first	first	JJ
cord-002808-84np9brx	180	11	dock	dock	VB
cord-002808-84np9brx	180	12	into	into	IN
cord-002808-84np9brx	180	13	a	a	DT
cord-002808-84np9brx	180	14	substrate	substrate	NN
cord-002808-84np9brx	180	15	binding	bind	VBG
cord-002808-84np9brx	180	16	site	site	NN
cord-002808-84np9brx	180	17	prior	prior	RB
cord-002808-84np9brx	180	18	to	to	TO
cord-002808-84np9brx	180	19	transfer	transfer	VB
cord-002808-84np9brx	180	20	to	to	IN
cord-002808-84np9brx	180	21	the	the	DT
cord-002808-84np9brx	180	22	catalytic	catalytic	JJ
cord-002808-84np9brx	180	23	active	active	JJ
cord-002808-84np9brx	180	24	site	site	NN
cord-002808-84np9brx	180	25	for	for	IN
cord-002808-84np9brx	180	26	proteolysis	proteolysis	NN
cord-002808-84np9brx	180	27	[	[	-LRB-
cord-002808-84np9brx	180	28	90	90	CD
cord-002808-84np9brx	180	29	]	]	-RRB-
cord-002808-84np9brx	180	30	.	.	.
cord-002808-84np9brx	181	1	γ	γ	NNP
cord-002808-84np9brx	181	2	-	-	HYPH
cord-002808-84np9brx	181	3	sec	sec	NNP
cord-002808-84np9brx	181	4	inhibitors	inhibitor	NNS
cord-002808-84np9brx	181	5	perturb	perturb	VBP
cord-002808-84np9brx	181	6	the	the	DT
cord-002808-84np9brx	181	7	global	global	JJ
cord-002808-84np9brx	181	8	structure	structure	NN
cord-002808-84np9brx	181	9	of	of	IN
cord-002808-84np9brx	181	10	the	the	DT
cord-002808-84np9brx	181	11	γ	γ	NNP
cord-002808-84np9brx	181	12	-	-	HYPH
cord-002808-84np9brx	181	13	sec	sec	NNP
cord-002808-84np9brx	181	14	complex	complex	NN
cord-002808-84np9brx	181	15	and	and	CC
cord-002808-84np9brx	181	16	may	may	MD
cord-002808-84np9brx	181	17	therefore	therefore	RB
cord-002808-84np9brx	181	18	prevent	prevent	VB
cord-002808-84np9brx	181	19	initial	initial	JJ
cord-002808-84np9brx	181	20	substrate	substrate	NN
cord-002808-84np9brx	181	21	docking	dock	VBG
cord-002808-84np9brx	181	22	[	[	-LRB-
cord-002808-84np9brx	181	23	91	91	CD
cord-002808-84np9brx	181	24	,	,	,
cord-002808-84np9brx	181	25	92	92	CD
cord-002808-84np9brx	181	26	]	]	-RRB-
cord-002808-84np9brx	181	27	.	.	.
cord-002808-84np9brx	182	1	As	as	IN
cord-002808-84np9brx	182	2	discussed	discuss	VBN
cord-002808-84np9brx	182	3	above	above	RB
cord-002808-84np9brx	182	4	,	,	,
cord-002808-84np9brx	182	5	many	many	JJ
cord-002808-84np9brx	182	6	host	host	NN
cord-002808-84np9brx	182	7	proteins	protein	NNS
cord-002808-84np9brx	182	8	and	and	CC
cord-002808-84np9brx	182	9	pathways	pathway	NNS
cord-002808-84np9brx	182	10	are	be	VBP
cord-002808-84np9brx	182	11	expoited	expoite	VBN
cord-002808-84np9brx	182	12	by	by	IN
cord-002808-84np9brx	182	13	HPV	HPV	NNP
cord-002808-84np9brx	182	14	to	to	TO
cord-002808-84np9brx	182	15	facilitate	facilitate	VB
cord-002808-84np9brx	182	16	virion	virion	NN
cord-002808-84np9brx	182	17	trafficking	trafficking	NN
cord-002808-84np9brx	182	18	and	and	CC
cord-002808-84np9brx	182	19	viral	viral	JJ
cord-002808-84np9brx	182	20	infection	infection	NN
cord-002808-84np9brx	182	21	,	,	,
cord-002808-84np9brx	182	22	but	but	CC
cord-002808-84np9brx	182	23	some	some	DT
cord-002808-84np9brx	182	24	proteins	protein	NNS
cord-002808-84np9brx	182	25	can	can	MD
cord-002808-84np9brx	182	26	restrict	restrict	VB
cord-002808-84np9brx	182	27	HPV	HPV	NNP
cord-002808-84np9brx	182	28	infection	infection	NN
cord-002808-84np9brx	182	29	suggesting	suggest	VBG
cord-002808-84np9brx	182	30	an	an	DT
cord-002808-84np9brx	182	31	inherent	inherent	JJ
cord-002808-84np9brx	182	32	anti	anti	JJ
cord-002808-84np9brx	182	33	-	-	JJ
cord-002808-84np9brx	182	34	papillomaviral	papillomaviral	JJ
cord-002808-84np9brx	182	35	function	function	NN
cord-002808-84np9brx	182	36	.	.	.
cord-002808-84np9brx	183	1	The	the	DT
cord-002808-84np9brx	183	2	endosomal	endosomal	NNP
cord-002808-84np9brx	183	3	protein	protein	NN
cord-002808-84np9brx	183	4	stannin	stannin	NNP
cord-002808-84np9brx	183	5	restricts	restrict	VBZ
cord-002808-84np9brx	183	6	HPV	hpv	NN
cord-002808-84np9brx	183	7	infection	infection	NN
cord-002808-84np9brx	183	8	by	by	IN
cord-002808-84np9brx	183	9	rerouting	reroute	VBG
cord-002808-84np9brx	183	10	virions	virion	NNS
cord-002808-84np9brx	183	11	away	away	RB
cord-002808-84np9brx	183	12	from	from	IN
cord-002808-84np9brx	183	13	the	the	DT
cord-002808-84np9brx	183	14	TGN	TGN	NNP
cord-002808-84np9brx	183	15	to	to	TO
cord-002808-84np9brx	183	16	degradative	degradative	VB
cord-002808-84np9brx	183	17	compartments	compartment	NNS
cord-002808-84np9brx	183	18	[	[	-LRB-
cord-002808-84np9brx	183	19	93	93	CD
cord-002808-84np9brx	183	20	]	]	-RRB-
cord-002808-84np9brx	183	21	.	.	.
cord-002808-84np9brx	184	1	Similarly	similarly	RB
cord-002808-84np9brx	184	2	,	,	,
cord-002808-84np9brx	184	3	the	the	DT
cord-002808-84np9brx	184	4	α	α	NNP
cord-002808-84np9brx	184	5	-	-	HYPH
cord-002808-84np9brx	184	6	defensin	defensin	NNP
cord-002808-84np9brx	184	7	HD5	HD5	NNP
cord-002808-84np9brx	184	8	alters	alter	VBZ
cord-002808-84np9brx	184	9	L2	L2	NNP
cord-002808-84np9brx	184	10	/	/	SYM
cord-002808-84np9brx	184	11	vDNA	vdna	NN
cord-002808-84np9brx	184	12	trafficking	trafficking	NN
cord-002808-84np9brx	184	13	,	,	,
cord-002808-84np9brx	184	14	accelerating	accelerate	VBG
cord-002808-84np9brx	184	15	the	the	DT
cord-002808-84np9brx	184	16	degradation	degradation	NN
cord-002808-84np9brx	184	17	of	of	IN
cord-002808-84np9brx	184	18	virions	virion	NNS
cord-002808-84np9brx	184	19	within	within	IN
cord-002808-84np9brx	184	20	LE	LE	NNP
cord-002808-84np9brx	184	21	/	/	SYM
cord-002808-84np9brx	184	22	lysosomal	lysosomal	JJ
cord-002808-84np9brx	184	23	compartments	compartment	NNS
cord-002808-84np9brx	184	24	to	to	TO
cord-002808-84np9brx	184	25	restrict	restrict	VB
cord-002808-84np9brx	184	26	HPV	hpv	NN
cord-002808-84np9brx	184	27	infection	infection	NN
cord-002808-84np9brx	184	28	[	[	-LRB-
cord-002808-84np9brx	184	29	94	94	CD
cord-002808-84np9brx	184	30	]	]	-RRB-
cord-002808-84np9brx	184	31	.	.	.
cord-002808-84np9brx	185	1	Stannin	Stannin	NNP
cord-002808-84np9brx	185	2	appears	appear	VBZ
cord-002808-84np9brx	185	3	to	to	TO
cord-002808-84np9brx	185	4	work	work	VB
cord-002808-84np9brx	185	5	by	by	IN
cord-002808-84np9brx	185	6	blocking	block	VBG
cord-002808-84np9brx	185	7	association	association	NNP
cord-002808-84np9brx	185	8	of	of	IN
cord-002808-84np9brx	185	9	L2	L2	NNP
cord-002808-84np9brx	185	10	with	with	IN
cord-002808-84np9brx	185	11	retromer	retromer	NNP
cord-002808-84np9brx	185	12	,	,	,
cord-002808-84np9brx	185	13	to	to	TO
cord-002808-84np9brx	185	14	prevent	prevent	VB
cord-002808-84np9brx	185	15	retrograde	retrograde	JJ
cord-002808-84np9brx	185	16	trafficking	trafficking	NN
cord-002808-84np9brx	185	17	of	of	IN
cord-002808-84np9brx	185	18	L2	l2	NN
cord-002808-84np9brx	185	19	/	/	SYM
cord-002808-84np9brx	185	20	vDNA	vdna	NN
cord-002808-84np9brx	185	21	,	,	,
cord-002808-84np9brx	185	22	causing	cause	VBG
cord-002808-84np9brx	185	23	an	an	DT
cord-002808-84np9brx	185	24	increased	increase	VBN
cord-002808-84np9brx	185	25	accumulation	accumulation	NN
cord-002808-84np9brx	185	26	of	of	IN
cord-002808-84np9brx	185	27	L2	L2	NNP
cord-002808-84np9brx	185	28	/	/	,
cord-002808-84np9brx	185	29	vDNA	vdna	NN
cord-002808-84np9brx	185	30	in	in	IN
cord-002808-84np9brx	185	31	LAMP1-positive	LAMP1-positive	NNP
cord-002808-84np9brx	185	32	lysosomal	lysosomal	JJ
cord-002808-84np9brx	185	33	compartments	compartment	NNS
cord-002808-84np9brx	185	34	[	[	-LRB-
cord-002808-84np9brx	185	35	93	93	CD
cord-002808-84np9brx	185	36	]	]	-RRB-
cord-002808-84np9brx	185	37	.	.	.
cord-002808-84np9brx	186	1	This	this	DT
cord-002808-84np9brx	186	2	is	be	VBZ
cord-002808-84np9brx	186	3	in	in	IN
cord-002808-84np9brx	186	4	contrast	contrast	NN
cord-002808-84np9brx	186	5	to	to	IN
cord-002808-84np9brx	186	6	retromer	retromer	VB
cord-002808-84np9brx	186	7	knockdown	knockdown	NN
cord-002808-84np9brx	186	8	or	or	CC
cord-002808-84np9brx	186	9	mutation	mutation	NN
cord-002808-84np9brx	186	10	of	of	IN
cord-002808-84np9brx	186	11	retromer	retromer	NN
cord-002808-84np9brx	186	12	binding	binding	NN
cord-002808-84np9brx	186	13	sites	site	NNS
cord-002808-84np9brx	186	14	in	in	IN
cord-002808-84np9brx	186	15	L2	L2	NNP
cord-002808-84np9brx	186	16	,	,	,
cord-002808-84np9brx	186	17	which	which	WDT
cord-002808-84np9brx	186	18	instead	instead	RB
cord-002808-84np9brx	186	19	cause	cause	VBP
cord-002808-84np9brx	186	20	a	a	DT
cord-002808-84np9brx	186	21	trafficking	trafficking	NN
cord-002808-84np9brx	186	22	block	block	NN
cord-002808-84np9brx	186	23	within	within	IN
cord-002808-84np9brx	186	24	EEA1-positive	EEA1-positive	NNP
cord-002808-84np9brx	186	25	endosomal	endosomal	NNP
cord-002808-84np9brx	186	26	compartments	compartment	NNS
cord-002808-84np9brx	186	27	[	[	-LRB-
cord-002808-84np9brx	186	28	48	48	CD
cord-002808-84np9brx	186	29	]	]	-RRB-
cord-002808-84np9brx	186	30	.	.	.
cord-002808-84np9brx	187	1	Rather	rather	RB
cord-002808-84np9brx	187	2	than	than	IN
cord-002808-84np9brx	187	3	directly	directly	RB
cord-002808-84np9brx	187	4	inhibiting	inhibit	VBG
cord-002808-84np9brx	187	5	the	the	DT
cord-002808-84np9brx	187	6	L2-retromer	L2-retromer	NNP
cord-002808-84np9brx	187	7	association	association	NN
cord-002808-84np9brx	187	8	,	,	,
cord-002808-84np9brx	187	9	stannin	stannin	NNP
cord-002808-84np9brx	187	10	likely	likely	RB
cord-002808-84np9brx	187	11	blocks	block	VBZ
cord-002808-84np9brx	187	12	the	the	DT
cord-002808-84np9brx	187	13	insertion	insertion	NN
cord-002808-84np9brx	187	14	and	and	CC
cord-002808-84np9brx	187	15	protrusion	protrusion	NN
cord-002808-84np9brx	187	16	of	of	IN
cord-002808-84np9brx	187	17	L2	l2	NN
cord-002808-84np9brx	187	18	within	within	IN
cord-002808-84np9brx	187	19	vesicular	vesicular	JJ
cord-002808-84np9brx	187	20	membranes	membrane	NNS
cord-002808-84np9brx	187	21	to	to	TO
cord-002808-84np9brx	187	22	indirectly	indirectly	RB
cord-002808-84np9brx	187	23	prevent	prevent	VB
cord-002808-84np9brx	187	24	binding	binding	NN
cord-002808-84np9brx	187	25	and	and	CC
cord-002808-84np9brx	187	26	recruitment	recruitment	NN
cord-002808-84np9brx	187	27	of	of	IN
cord-002808-84np9brx	187	28	retromer	retromer	NNP
cord-002808-84np9brx	187	29	.	.	.
cord-002808-84np9brx	188	1	Similarly	similarly	RB
cord-002808-84np9brx	188	2	,	,	,
cord-002808-84np9brx	188	3	HD5	HD5	NNP
cord-002808-84np9brx	188	4	may	may	MD
cord-002808-84np9brx	188	5	induce	induce	VB
cord-002808-84np9brx	188	6	aberrant	aberrant	JJ
cord-002808-84np9brx	188	7	trafficking	trafficking	NN
cord-002808-84np9brx	188	8	of	of	IN
cord-002808-84np9brx	188	9	L2	l2	NN
cord-002808-84np9brx	188	10	/	/	,
cord-002808-84np9brx	188	11	vDNA	vdna	RB
cord-002808-84np9brx	188	12	by	by	IN
cord-002808-84np9brx	188	13	directly	directly	RB
cord-002808-84np9brx	188	14	binding	bind	VBG
cord-002808-84np9brx	188	15	the	the	DT
cord-002808-84np9brx	188	16	virion	virion	NN
cord-002808-84np9brx	188	17	to	to	TO
cord-002808-84np9brx	188	18	interfere	interfere	VB
cord-002808-84np9brx	188	19	with	with	IN
cord-002808-84np9brx	188	20	L2	l2	NN
cord-002808-84np9brx	188	21	insertion	insertion	NN
cord-002808-84np9brx	188	22	and	and	CC
cord-002808-84np9brx	188	23	protrusion	protrusion	NN
cord-002808-84np9brx	188	24	[	[	-LRB-
cord-002808-84np9brx	188	25	94	94	CD
cord-002808-84np9brx	188	26	]	]	-RRB-
cord-002808-84np9brx	188	27	.	.	.
cord-002808-84np9brx	189	1	Interestingly	interestingly	RB
cord-002808-84np9brx	189	2	,	,	,
cord-002808-84np9brx	189	3	interferon	interferon	NN
cord-002808-84np9brx	189	4	gamma	gamma	NN
cord-002808-84np9brx	189	5	has	have	VBZ
cord-002808-84np9brx	189	6	recently	recently	RB
cord-002808-84np9brx	189	7	been	be	VBN
cord-002808-84np9brx	189	8	found	find	VBN
cord-002808-84np9brx	189	9	to	to	TO
cord-002808-84np9brx	189	10	restrict	restrict	VB
cord-002808-84np9brx	189	11	HPV	hpv	NN
cord-002808-84np9brx	189	12	infection	infection	NN
cord-002808-84np9brx	189	13	in	in	IN
cord-002808-84np9brx	189	14	an	an	DT
cord-002808-84np9brx	189	15	L2-dependent	L2-dependent	NNP
cord-002808-84np9brx	189	16	and	and	CC
cord-002808-84np9brx	189	17	type	type	NN
cord-002808-84np9brx	189	18	-	-	HYPH
cord-002808-84np9brx	189	19	specific	specific	JJ
cord-002808-84np9brx	189	20	manner	manner	NN
cord-002808-84np9brx	189	21	,	,	,
cord-002808-84np9brx	189	22	decreasing	decrease	VBG
cord-002808-84np9brx	189	23	the	the	DT
cord-002808-84np9brx	189	24	proteolytic	proteolytic	JJ
cord-002808-84np9brx	189	25	degradation	degradation	NN
cord-002808-84np9brx	189	26	of	of	IN
cord-002808-84np9brx	189	27	L1	L1	NNP
cord-002808-84np9brx	189	28	capsid	capsid	NN
cord-002808-84np9brx	189	29	and	and	CC
cord-002808-84np9brx	189	30	causing	cause	VBG
cord-002808-84np9brx	189	31	a	a	DT
cord-002808-84np9brx	189	32	block	block	NN
cord-002808-84np9brx	189	33	of	of	IN
cord-002808-84np9brx	189	34	L2	l2	NN
cord-002808-84np9brx	189	35	/	/	,
cord-002808-84np9brx	189	36	vDNA	vdna	NN
cord-002808-84np9brx	189	37	in	in	IN
cord-002808-84np9brx	189	38	LE	LE	NNP
cord-002808-84np9brx	189	39	/	/	SYM
cord-002808-84np9brx	189	40	MVB	MVB	NNP
cord-002808-84np9brx	189	41	/	/	SYM
cord-002808-84np9brx	189	42	lysosomal	lysosomal	JJ
cord-002808-84np9brx	189	43	compartments	compartment	NNS
cord-002808-84np9brx	189	44	[	[	-LRB-
cord-002808-84np9brx	189	45	95	95	CD
cord-002808-84np9brx	189	46	]	]	-RRB-
cord-002808-84np9brx	189	47	.	.	.
cord-002808-84np9brx	190	1	Cathepsin	Cathepsin	NNP
cord-002808-84np9brx	190	2	proteases	protease	NNS
cord-002808-84np9brx	190	3	also	also	RB
cord-002808-84np9brx	190	4	appear	appear	VBP
cord-002808-84np9brx	190	5	to	to	TO
cord-002808-84np9brx	190	6	limit	limit	VB
cord-002808-84np9brx	190	7	HPV	HPV	NNP
cord-002808-84np9brx	190	8	,	,	,
cord-002808-84np9brx	190	9	as	as	IN
cord-002808-84np9brx	190	10	infection	infection	NN
cord-002808-84np9brx	190	11	is	be	VBZ
cord-002808-84np9brx	190	12	increased	increase	VBN
cord-002808-84np9brx	190	13	upon	upon	IN
cord-002808-84np9brx	190	14	genetic	genetic	JJ
cord-002808-84np9brx	190	15	knockout	knockout	NN
cord-002808-84np9brx	190	16	,	,	,
cord-002808-84np9brx	190	17	siRNA	siRNA	NNP
cord-002808-84np9brx	190	18	silencing	silencing	NN
cord-002808-84np9brx	190	19	,	,	,
cord-002808-84np9brx	190	20	or	or	CC
cord-002808-84np9brx	190	21	biochemical	biochemical	JJ
cord-002808-84np9brx	190	22	inhibition	inhibition	NN
cord-002808-84np9brx	190	23	[	[	-LRB-
cord-002808-84np9brx	190	24	22	22	CD
cord-002808-84np9brx	190	25	,	,	,
cord-002808-84np9brx	190	26	96	96	CD
cord-002808-84np9brx	190	27	]	]	-RRB-
cord-002808-84np9brx	190	28	;	;	:
cord-002808-84np9brx	190	29	this	this	DT
cord-002808-84np9brx	190	30	is	be	VBZ
cord-002808-84np9brx	190	31	contrary	contrary	JJ
cord-002808-84np9brx	190	32	to	to	IN
cord-002808-84np9brx	190	33	other	other	JJ
cord-002808-84np9brx	190	34	non	non	JJ
cord-002808-84np9brx	190	35	-	-	JJ
cord-002808-84np9brx	190	36	enveloped	enveloped	JJ
cord-002808-84np9brx	190	37	viruses	virus	NNS
cord-002808-84np9brx	190	38	,	,	,
cord-002808-84np9brx	190	39	like	like	IN
cord-002808-84np9brx	190	40	reoviruses	reovirus	NNS
cord-002808-84np9brx	190	41	and	and	CC
cord-002808-84np9brx	190	42	adeno	adeno	NN
cord-002808-84np9brx	190	43	-	-	HYPH
cord-002808-84np9brx	190	44	associated	associate	VBN
cord-002808-84np9brx	190	45	viruses	virus	NNS
cord-002808-84np9brx	190	46	,	,	,
cord-002808-84np9brx	190	47	which	which	WDT
cord-002808-84np9brx	190	48	depend	depend	VBP
cord-002808-84np9brx	190	49	on	on	IN
cord-002808-84np9brx	190	50	these	these	DT
cord-002808-84np9brx	190	51	endosomal	endosomal	NNP
cord-002808-84np9brx	190	52	proteases	protease	NNS
cord-002808-84np9brx	190	53	for	for	IN
cord-002808-84np9brx	190	54	uncoating	uncoate	VBG
cord-002808-84np9brx	190	55	[	[	-LRB-
cord-002808-84np9brx	190	56	97	97	CD
cord-002808-84np9brx	190	57	,	,	,
cord-002808-84np9brx	190	58	98	98	CD
cord-002808-84np9brx	190	59	]	]	-RRB-
cord-002808-84np9brx	190	60	.	.	.
cord-002808-84np9brx	191	1	Vimentin	Vimentin	NNP
cord-002808-84np9brx	191	2	is	be	VBZ
cord-002808-84np9brx	191	3	another	another	DT
cord-002808-84np9brx	191	4	recently	recently	RB
cord-002808-84np9brx	191	5	reported	report	VBN
cord-002808-84np9brx	191	6	inhibitory	inhibitory	JJ
cord-002808-84np9brx	191	7	factor	factor	NN
cord-002808-84np9brx	191	8	,	,	,
cord-002808-84np9brx	191	9	found	find	VBN
cord-002808-84np9brx	191	10	to	to	TO
cord-002808-84np9brx	191	11	limit	limit	VB
cord-002808-84np9brx	191	12	infection	infection	NN
cord-002808-84np9brx	191	13	at	at	IN
cord-002808-84np9brx	191	14	the	the	DT
cord-002808-84np9brx	191	15	level	level	NN
cord-002808-84np9brx	191	16	of	of	IN
cord-002808-84np9brx	191	17	viral	viral	JJ
cord-002808-84np9brx	191	18	entry	entry	NN
cord-002808-84np9brx	191	19	[	[	-LRB-
cord-002808-84np9brx	191	20	99	99	CD
cord-002808-84np9brx	191	21	]	]	-RRB-
cord-002808-84np9brx	191	22	.	.	.
cord-002808-84np9brx	192	1	Much	much	JJ
cord-002808-84np9brx	192	2	will	will	MD
cord-002808-84np9brx	192	3	be	be	VB
cord-002808-84np9brx	192	4	gained	gain	VBN
cord-002808-84np9brx	192	5	from	from	IN
cord-002808-84np9brx	192	6	further	further	JJ
cord-002808-84np9brx	192	7	mechanistic	mechanistic	JJ
cord-002808-84np9brx	192	8	studies	study	NNS
cord-002808-84np9brx	192	9	of	of	IN
cord-002808-84np9brx	192	10	these	these	DT
cord-002808-84np9brx	192	11	inhibitory	inhibitory	JJ
cord-002808-84np9brx	192	12	host	host	NN
cord-002808-84np9brx	192	13	factors	factor	NNS
cord-002808-84np9brx	192	14	.	.	.
cord-002808-84np9brx	193	1	Prior	prior	RB
cord-002808-84np9brx	193	2	to	to	IN
cord-002808-84np9brx	193	3	2013	2013	CD
cord-002808-84np9brx	193	4	,	,	,
cord-002808-84np9brx	193	5	the	the	DT
cord-002808-84np9brx	193	6	consensus	consensus	NN
cord-002808-84np9brx	193	7	view	view	NN
cord-002808-84np9brx	193	8	was	be	VBD
cord-002808-84np9brx	193	9	that	that	IN
cord-002808-84np9brx	193	10	the	the	DT
cord-002808-84np9brx	193	11	L2	L2	NNP
cord-002808-84np9brx	193	12	/	/	SYM
cord-002808-84np9brx	193	13	vDNA	vdna	RB
cord-002808-84np9brx	193	14	complex	complex	NNP
cord-002808-84np9brx	193	15	egressed	egress	VBD
cord-002808-84np9brx	193	16	from	from	IN
cord-002808-84np9brx	193	17	endosomal	endosomal	NNP
cord-002808-84np9brx	193	18	compartments	compartment	NNS
cord-002808-84np9brx	193	19	into	into	IN
cord-002808-84np9brx	193	20	the	the	DT
cord-002808-84np9brx	193	21	cytosol	cytosol	NN
cord-002808-84np9brx	193	22	,	,	,
cord-002808-84np9brx	193	23	as	as	IN
cord-002808-84np9brx	193	24	is	be	VBZ
cord-002808-84np9brx	193	25	the	the	DT
cord-002808-84np9brx	193	26	case	case	NN
cord-002808-84np9brx	193	27	for	for	IN
cord-002808-84np9brx	193	28	many	many	JJ
cord-002808-84np9brx	193	29	other	other	JJ
cord-002808-84np9brx	193	30	non	non	JJ
cord-002808-84np9brx	193	31	-	-	JJ
cord-002808-84np9brx	193	32	enveloped	enveloped	JJ
cord-002808-84np9brx	193	33	viruses	virus	NNS
cord-002808-84np9brx	193	34	[	[	-LRB-
cord-002808-84np9brx	193	35	100	100	CD
cord-002808-84np9brx	193	36	]	]	-RRB-
cord-002808-84np9brx	193	37	[	[	-LRB-
cord-002808-84np9brx	193	38	101	101	CD
cord-002808-84np9brx	193	39	]	]	-RRB-
cord-002808-84np9brx	193	40	[	[	-LRB-
cord-002808-84np9brx	193	41	102	102	CD
cord-002808-84np9brx	193	42	]	]	-RRB-
cord-002808-84np9brx	193	43	.	.	.
cord-002808-84np9brx	194	1	Thus	thus	RB
cord-002808-84np9brx	194	2	,	,	,
cord-002808-84np9brx	194	3	discovery	discovery	NN
cord-002808-84np9brx	194	4	of	of	IN
cord-002808-84np9brx	194	5	the	the	DT
cord-002808-84np9brx	194	6	TGN	TGN	NNP
cord-002808-84np9brx	194	7	as	as	IN
cord-002808-84np9brx	194	8	an	an	DT
cord-002808-84np9brx	194	9	important	important	JJ
cord-002808-84np9brx	194	10	stop	stop	NN
cord-002808-84np9brx	194	11	in	in	IN
cord-002808-84np9brx	194	12	the	the	DT
cord-002808-84np9brx	194	13	retrograde	retrograde	JJ
cord-002808-84np9brx	194	14	route	route	NN
cord-002808-84np9brx	194	15	of	of	IN
cord-002808-84np9brx	194	16	incoming	incoming	JJ
cord-002808-84np9brx	194	17	L2	L2	NNP
cord-002808-84np9brx	194	18	/	/	,
cord-002808-84np9brx	194	19	vDNA	vdna	NN
cord-002808-84np9brx	194	20	was	be	VBD
cord-002808-84np9brx	194	21	a	a	DT
cord-002808-84np9brx	194	22	major	major	JJ
cord-002808-84np9brx	194	23	advance	advance	NN
cord-002808-84np9brx	194	24	in	in	IN
cord-002808-84np9brx	194	25	the	the	DT
cord-002808-84np9brx	194	26	field	field	NN
cord-002808-84np9brx	194	27	[	[	-LRB-
cord-002808-84np9brx	194	28	23	23	CD
cord-002808-84np9brx	194	29	,	,	,
cord-002808-84np9brx	194	30	47	47	CD
cord-002808-84np9brx	194	31	]	]	-RRB-
cord-002808-84np9brx	194	32	.	.	.
cord-002808-84np9brx	195	1	Initially	initially	RB
cord-002808-84np9brx	195	2	,	,	,
cord-002808-84np9brx	195	3	the	the	DT
cord-002808-84np9brx	195	4	L2	L2	NNP
cord-002808-84np9brx	195	5	/	/	,
cord-002808-84np9brx	195	6	vDNA	vdna	RB
cord-002808-84np9brx	195	7	was	be	VBD
cord-002808-84np9brx	195	8	believed	believe	VBN
cord-002808-84np9brx	195	9	to	to	TO
cord-002808-84np9brx	195	10	penetrate	penetrate	VB
cord-002808-84np9brx	195	11	the	the	DT
cord-002808-84np9brx	195	12	TGN	TGN	NNP
cord-002808-84np9brx	195	13	directly	directly	RB
cord-002808-84np9brx	195	14	and	and	CC
cord-002808-84np9brx	195	15	wait	wait	VB
cord-002808-84np9brx	195	16	in	in	IN
cord-002808-84np9brx	195	17	the	the	DT
cord-002808-84np9brx	195	18	cytosol	cytosol	NN
cord-002808-84np9brx	195	19	prior	prior	RB
cord-002808-84np9brx	195	20	to	to	IN
cord-002808-84np9brx	195	21	nuclear	nuclear	JJ
cord-002808-84np9brx	195	22	entry	entry	NN
cord-002808-84np9brx	195	23	.	.	.
cord-002808-84np9brx	196	1	Cell	cell	NN
cord-002808-84np9brx	196	2	cycle	cycle	NN
cord-002808-84np9brx	196	3	progression	progression	NN
cord-002808-84np9brx	196	4	into	into	IN
cord-002808-84np9brx	196	5	mitosis	mitosis	NN
cord-002808-84np9brx	196	6	is	be	VBZ
cord-002808-84np9brx	196	7	known	know	VBN
cord-002808-84np9brx	196	8	to	to	TO
cord-002808-84np9brx	196	9	be	be	VB
cord-002808-84np9brx	196	10	important	important	JJ
cord-002808-84np9brx	196	11	for	for	IN
cord-002808-84np9brx	196	12	HPV	hpv	NN
cord-002808-84np9brx	196	13	infection	infection	NN
cord-002808-84np9brx	196	14	[	[	-LRB-
cord-002808-84np9brx	196	15	103	103	CD
cord-002808-84np9brx	196	16	]	]	-RRB-
cord-002808-84np9brx	196	17	,	,	,
cord-002808-84np9brx	196	18	and	and	CC
cord-002808-84np9brx	196	19	nuclear	nuclear	JJ
cord-002808-84np9brx	196	20	envelope	envelope	NN
cord-002808-84np9brx	196	21	breakdown	breakdown	NN
cord-002808-84np9brx	196	22	was	be	VBD
cord-002808-84np9brx	196	23	thought	think	VBN
cord-002808-84np9brx	196	24	to	to	TO
cord-002808-84np9brx	196	25	facilitate	facilitate	VB
cord-002808-84np9brx	196	26	L2	L2	NNP
cord-002808-84np9brx	196	27	/	/	,
cord-002808-84np9brx	196	28	vDNA	vdna	RB
cord-002808-84np9brx	196	29	transfer	transfer	NN
cord-002808-84np9brx	196	30	from	from	IN
cord-002808-84np9brx	196	31	the	the	DT
cord-002808-84np9brx	196	32	cytosol	cytosol	NN
cord-002808-84np9brx	196	33	into	into	IN
cord-002808-84np9brx	196	34	the	the	DT
cord-002808-84np9brx	196	35	nucleus	nucleus	NN
cord-002808-84np9brx	196	36	like	like	IN
cord-002808-84np9brx	196	37	some	some	DT
cord-002808-84np9brx	196	38	retroviruses	retrovirus	NNS
cord-002808-84np9brx	196	39	[	[	-LRB-
cord-002808-84np9brx	196	40	50	50	CD
cord-002808-84np9brx	196	41	,	,	,
cord-002808-84np9brx	196	42	104	104	CD
cord-002808-84np9brx	196	43	]	]	-RRB-
cord-002808-84np9brx	196	44	.	.	.
cord-002808-84np9brx	197	1	Recent	recent	JJ
cord-002808-84np9brx	197	2	work	work	NN
cord-002808-84np9brx	197	3	supports	support	VBZ
cord-002808-84np9brx	197	4	a	a	DT
cord-002808-84np9brx	197	5	model	model	NN
cord-002808-84np9brx	198	1	where	where	WRB
cord-002808-84np9brx	198	2	,	,	,
cord-002808-84np9brx	198	3	at	at	IN
cord-002808-84np9brx	198	4	the	the	DT
cord-002808-84np9brx	198	5	onset	onset	NN
cord-002808-84np9brx	198	6	of	of	IN
cord-002808-84np9brx	198	7	mitosis	mitosis	NN
cord-002808-84np9brx	198	8	,	,	,
cord-002808-84np9brx	198	9	when	when	WRB
cord-002808-84np9brx	198	10	the	the	DT
cord-002808-84np9brx	198	11	Golgi	Golgi	NNP
cord-002808-84np9brx	198	12	and	and	CC
cord-002808-84np9brx	198	13	TGN	TGN	NNP
cord-002808-84np9brx	198	14	naturally	naturally	RB
cord-002808-84np9brx	198	15	begins	begin	VBZ
cord-002808-84np9brx	198	16	to	to	TO
cord-002808-84np9brx	198	17	fragment	fragment	VB
cord-002808-84np9brx	198	18	and	and	CC
cord-002808-84np9brx	198	19	vesiculate	vesiculate	NN
cord-002808-84np9brx	198	20	,	,	,
cord-002808-84np9brx	198	21	the	the	DT
cord-002808-84np9brx	198	22	vesicle	vesicle	NN
cord-002808-84np9brx	198	23	-	-	HYPH
cord-002808-84np9brx	198	24	bound	bind	VBN
cord-002808-84np9brx	198	25	vDNA	vdna	WDT
cord-002808-84np9brx	198	26	egresses	egress	NNS
cord-002808-84np9brx	198	27	from	from	IN
cord-002808-84np9brx	198	28	what	what	WP
cord-002808-84np9brx	198	29	was	be	VBD
cord-002808-84np9brx	198	30	the	the	DT
cord-002808-84np9brx	198	31	interphase	interphase	NN
cord-002808-84np9brx	198	32	TGN	TGN	NNP
cord-002808-84np9brx	198	33	(	(	-LRB-
cord-002808-84np9brx	198	34	Figure	figure	NN
cord-002808-84np9brx	198	35	3	3	CD
cord-002808-84np9brx	198	36	)	)	-RRB-
cord-002808-84np9brx	198	37	.	.	.
cord-002808-84np9brx	199	1	The	the	DT
cord-002808-84np9brx	199	2	Sapp	Sapp	NNP
cord-002808-84np9brx	199	3	laboratory	laboratory	NN
cord-002808-84np9brx	199	4	pioneered	pioneer	VBD
cord-002808-84np9brx	199	5	an	an	DT
cord-002808-84np9brx	199	6	EdU	edu	NN
cord-002808-84np9brx	199	7	/	/	,
cord-002808-84np9brx	199	8	vDNA	vdna	JJ
cord-002808-84np9brx	199	9	staining	staining	NN
cord-002808-84np9brx	199	10	technique	technique	NN
cord-002808-84np9brx	199	11	based	base	VBN
cord-002808-84np9brx	199	12	on	on	IN
cord-002808-84np9brx	199	13	selective	selective	JJ
cord-002808-84np9brx	199	14	membrane	membrane	NN
cord-002808-84np9brx	199	15	permeabilization	permeabilization	NN
cord-002808-84np9brx	199	16	and	and	CC
cord-002808-84np9brx	199	17	sequential	sequential	JJ
cord-002808-84np9brx	199	18	EdU	edu	NN
cord-002808-84np9brx	199	19	labeling	label	VBG
cord-002808-84np9brx	199	20	to	to	TO
cord-002808-84np9brx	199	21	demonstrate	demonstrate	VB
cord-002808-84np9brx	199	22	the	the	DT
cord-002808-84np9brx	199	23	lumenal	lumenal	JJ
cord-002808-84np9brx	199	24	state	state	NN
cord-002808-84np9brx	199	25	of	of	IN
cord-002808-84np9brx	199	26	the	the	DT
cord-002808-84np9brx	199	27	vDNA	vdna	JJ
cord-002808-84np9brx	199	28	[	[	-LRB-
cord-002808-84np9brx	199	29	81	81	CD
cord-002808-84np9brx	199	30	]	]	-RRB-
cord-002808-84np9brx	199	31	.	.	.
cord-002808-84np9brx	200	1	While	while	IN
cord-002808-84np9brx	200	2	the	the	DT
cord-002808-84np9brx	200	3	exact	exact	JJ
cord-002808-84np9brx	200	4	nature	nature	NN
cord-002808-84np9brx	200	5	of	of	IN
cord-002808-84np9brx	200	6	these	these	DT
cord-002808-84np9brx	200	7	vesicles	vesicle	NNS
cord-002808-84np9brx	200	8	remains	remain	VBZ
cord-002808-84np9brx	200	9	unknown	unknown	JJ
cord-002808-84np9brx	200	10	,	,	,
cord-002808-84np9brx	200	11	immunofluorescence	immunofluorescence	NN
cord-002808-84np9brx	200	12	microscopy	microscopy	NN
cord-002808-84np9brx	200	13	reveals	reveal	VBZ
cord-002808-84np9brx	200	14	that	that	IN
cord-002808-84np9brx	200	15	these	these	DT
cord-002808-84np9brx	200	16	vDNA	vdna	RB
cord-002808-84np9brx	200	17	-	-	HYPH
cord-002808-84np9brx	200	18	containing	contain	VBG
cord-002808-84np9brx	200	19	vesicles	vesicle	NNS
cord-002808-84np9brx	200	20	stain	stain	VBP
cord-002808-84np9brx	200	21	negative	negative	JJ
cord-002808-84np9brx	200	22	for	for	IN
cord-002808-84np9brx	200	23	classical	classical	JJ
cord-002808-84np9brx	200	24	TGN	TGN	NNP
cord-002808-84np9brx	200	25	markers	marker	NNS
cord-002808-84np9brx	200	26	like	like	IN
cord-002808-84np9brx	200	27	TGN46	tgn46	NN
cord-002808-84np9brx	200	28	and	and	CC
cord-002808-84np9brx	200	29	p230	p230	NN
cord-002808-84np9brx	200	30	,	,	,
cord-002808-84np9brx	200	31	and	and	CC
cord-002808-84np9brx	200	32	appear	appear	VBP
cord-002808-84np9brx	200	33	to	to	TO
cord-002808-84np9brx	200	34	migrate	migrate	VB
cord-002808-84np9brx	200	35	along	along	IN
cord-002808-84np9brx	200	36	microtubules	microtubule	NNS
cord-002808-84np9brx	200	37	,	,	,
cord-002808-84np9brx	200	38	clustering	cluster	VBG
cord-002808-84np9brx	200	39	around	around	IN
cord-002808-84np9brx	200	40	the	the	DT
cord-002808-84np9brx	200	41	centrioles	centriole	NNS
cord-002808-84np9brx	200	42	during	during	IN
cord-002808-84np9brx	200	43	progression	progression	NN
cord-002808-84np9brx	200	44	from	from	IN
cord-002808-84np9brx	200	45	G2	G2	NNP
cord-002808-84np9brx	200	46	/	/	SYM
cord-002808-84np9brx	200	47	M	M	NNP
cord-002808-84np9brx	200	48	to	to	IN
cord-002808-84np9brx	200	49	prometaphase	prometaphase	NNP
cord-002808-84np9brx	200	50	[	[	-LRB-
cord-002808-84np9brx	200	51	51	51	CD
cord-002808-84np9brx	200	52	,	,	,
cord-002808-84np9brx	200	53	81	81	CD
cord-002808-84np9brx	200	54	]	]	-RRB-
cord-002808-84np9brx	200	55	.	.	.
cord-002808-84np9brx	201	1	L2	L2	NNP
cord-002808-84np9brx	201	2	likely	likely	RB
cord-002808-84np9brx	201	3	remains	remain	VBZ
cord-002808-84np9brx	201	4	in	in	IN
cord-002808-84np9brx	201	5	the	the	DT
cord-002808-84np9brx	201	6	protruding	protrude	VBG
cord-002808-84np9brx	201	7	conformation	conformation	NN
cord-002808-84np9brx	201	8	,	,	,
cord-002808-84np9brx	201	9	spanning	span	VBG
cord-002808-84np9brx	201	10	across	across	IN
cord-002808-84np9brx	201	11	the	the	DT
cord-002808-84np9brx	201	12	limiting	limit	VBG
cord-002808-84np9brx	201	13	membrane	membrane	NN
cord-002808-84np9brx	201	14	to	to	TO
cord-002808-84np9brx	201	15	coordinate	coordinate	VB
cord-002808-84np9brx	201	16	microtubule	microtubule	NN
cord-002808-84np9brx	201	17	-	-	HYPH
cord-002808-84np9brx	201	18	dependent	dependent	JJ
cord-002808-84np9brx	201	19	traffic	traffic	NN
cord-002808-84np9brx	201	20	of	of	IN
cord-002808-84np9brx	201	21	these	these	DT
cord-002808-84np9brx	201	22	vDNA	vdna	RB
cord-002808-84np9brx	201	23	-	-	HYPH
cord-002808-84np9brx	201	24	containing	contain	VBG
cord-002808-84np9brx	201	25	vesicles	vesicle	NNS
cord-002808-84np9brx	201	26	along	along	IN
cord-002808-84np9brx	201	27	the	the	DT
cord-002808-84np9brx	201	28	mitotic	mitotic	JJ
cord-002808-84np9brx	201	29	spindle	spindle	NN
cord-002808-84np9brx	201	30	[	[	-LRB-
cord-002808-84np9brx	201	31	81	81	CD
cord-002808-84np9brx	201	32	]	]	-RRB-
cord-002808-84np9brx	201	33	.	.	.
cord-002808-84np9brx	202	1	These	these	DT
cord-002808-84np9brx	202	2	vesicles	vesicle	NNS
cord-002808-84np9brx	202	3	eventually	eventually	RB
cord-002808-84np9brx	202	4	make	make	VBP
cord-002808-84np9brx	202	5	their	-PRON-	PRP$
cord-002808-84np9brx	202	6	way	way	NN
cord-002808-84np9brx	202	7	to	to	IN
cord-002808-84np9brx	202	8	the	the	DT
cord-002808-84np9brx	202	9	condensed	condense	VBN
cord-002808-84np9brx	202	10	chromosomes	chromosome	NNS
cord-002808-84np9brx	202	11	,	,	,
cord-002808-84np9brx	202	12	and	and	CC
cord-002808-84np9brx	202	13	by	by	IN
cord-002808-84np9brx	202	14	metaphase	metaphase	NN
cord-002808-84np9brx	202	15	,	,	,
cord-002808-84np9brx	202	16	vDNA	vdna	RB
cord-002808-84np9brx	202	17	can	can	MD
cord-002808-84np9brx	202	18	be	be	VB
cord-002808-84np9brx	202	19	seen	see	VBN
cord-002808-84np9brx	202	20	to	to	TO
cord-002808-84np9brx	202	21	be	be	VB
cord-002808-84np9brx	202	22	associated	associate	VBN
cord-002808-84np9brx	202	23	with	with	IN
cord-002808-84np9brx	202	24	and	and	CC
cord-002808-84np9brx	202	25	presumably	presumably	RB
cord-002808-84np9brx	202	26	bound	bind	VBN
cord-002808-84np9brx	202	27	to	to	IN
cord-002808-84np9brx	202	28	the	the	DT
cord-002808-84np9brx	202	29	host	host	NN
cord-002808-84np9brx	202	30	chromosomes	chromosome	NNS
cord-002808-84np9brx	202	31	[	[	-LRB-
cord-002808-84np9brx	202	32	49	49	CD
cord-002808-84np9brx	202	33	,	,	,
cord-002808-84np9brx	202	34	51	51	CD
cord-002808-84np9brx	202	35	,	,	,
cord-002808-84np9brx	202	36	81	81	CD
cord-002808-84np9brx	202	37	]	]	-RRB-
cord-002808-84np9brx	203	1	(	(	-LRB-
cord-002808-84np9brx	203	2	Figure	figure	NN
cord-002808-84np9brx	203	3	3	3	CD
cord-002808-84np9brx	203	4	)	)	-RRB-
cord-002808-84np9brx	203	5	.	.	.
cord-002808-84np9brx	204	1	From	from	IN
cord-002808-84np9brx	204	2	there	there	RB
cord-002808-84np9brx	204	3	,	,	,
cord-002808-84np9brx	204	4	the	the	DT
cord-002808-84np9brx	204	5	chromosome	chromosome	NN
cord-002808-84np9brx	204	6	-	-	HYPH
cord-002808-84np9brx	204	7	bound	bind	VBN
cord-002808-84np9brx	204	8	vDNA	vdna	WDT
cord-002808-84np9brx	204	9	is	be	VBZ
cord-002808-84np9brx	204	10	partitioned	partition	VBN
cord-002808-84np9brx	204	11	into	into	IN
cord-002808-84np9brx	204	12	daughter	daughter	NN
cord-002808-84np9brx	204	13	cells	cell	NNS
cord-002808-84np9brx	204	14	.	.	.
cord-002808-84np9brx	205	1	In	in	IN
cord-002808-84np9brx	205	2	this	this	DT
cord-002808-84np9brx	205	3	manner	manner	NN
cord-002808-84np9brx	205	4	,	,	,
cord-002808-84np9brx	205	5	infection	infection	NN
cord-002808-84np9brx	205	6	of	of	IN
cord-002808-84np9brx	205	7	both	both	DT
cord-002808-84np9brx	205	8	daughter	daughter	NN
cord-002808-84np9brx	205	9	cells	cell	NNS
cord-002808-84np9brx	205	10	is	be	VBZ
cord-002808-84np9brx	205	11	favored	favor	VBN
cord-002808-84np9brx	205	12	at	at	IN
cord-002808-84np9brx	205	13	an	an	DT
cord-002808-84np9brx	205	14	MOI	MOI	NNP
cord-002808-84np9brx	205	15	>	>	XX
cord-002808-84np9brx	205	16	2	2	CD
cord-002808-84np9brx	205	17	.	.	.
cord-002808-84np9brx	206	1	When	when	WRB
cord-002808-84np9brx	206	2	does	do	VBZ
cord-002808-84np9brx	206	3	the	the	DT
cord-002808-84np9brx	206	4	L2	L2	NNP
cord-002808-84np9brx	206	5	/	/	SYM
cord-002808-84np9brx	206	6	vDNA	vdna	RB
cord-002808-84np9brx	206	7	complex	complex	NN
cord-002808-84np9brx	206	8	fully	fully	RB
cord-002808-84np9brx	206	9	translocate	translocate	VBP
cord-002808-84np9brx	206	10	across	across	IN
cord-002808-84np9brx	206	11	the	the	DT
cord-002808-84np9brx	206	12	limiting	limit	VBG
cord-002808-84np9brx	206	13	membrane	membrane	NN
cord-002808-84np9brx	206	14	?	?	.
cord-002808-84np9brx	207	1	While	while	IN
cord-002808-84np9brx	207	2	useful	useful	JJ
cord-002808-84np9brx	207	3	for	for	IN
cord-002808-84np9brx	207	4	observing	observe	VBG
cord-002808-84np9brx	207	5	the	the	DT
cord-002808-84np9brx	207	6	trafficking	trafficking	NN
cord-002808-84np9brx	207	7	of	of	IN
cord-002808-84np9brx	207	8	vDNA	vdna	NN
cord-002808-84np9brx	207	9	during	during	IN
cord-002808-84np9brx	207	10	HPV	HPV	NNP
cord-002808-84np9brx	207	11	infection	infection	NN
cord-002808-84np9brx	207	12	,	,	,
cord-002808-84np9brx	207	13	standard	standard	JJ
cord-002808-84np9brx	207	14	subcellular	subcellular	JJ
cord-002808-84np9brx	207	15	localization	localization	NN
cord-002808-84np9brx	207	16	of	of	IN
cord-002808-84np9brx	207	17	EdU	edu	NN
cord-002808-84np9brx	207	18	-	-	HYPH
cord-002808-84np9brx	207	19	labeled	label	VBN
cord-002808-84np9brx	207	20	vDNA	vdna	RB
cord-002808-84np9brx	207	21	by	by	IN
cord-002808-84np9brx	207	22	microscopy	microscopy	NNS
cord-002808-84np9brx	207	23	is	be	VBZ
cord-002808-84np9brx	207	24	insufficient	insufficient	JJ
cord-002808-84np9brx	207	25	to	to	TO
cord-002808-84np9brx	207	26	reveal	reveal	VB
cord-002808-84np9brx	207	27	the	the	DT
cord-002808-84np9brx	207	28	actual	actual	JJ
cord-002808-84np9brx	207	29	translocation	translocation	NN
cord-002808-84np9brx	207	30	event	event	NN
cord-002808-84np9brx	207	31	.	.	.
cord-002808-84np9brx	208	1	Using	use	VBG
cord-002808-84np9brx	208	2	their	-PRON-	PRP$
cord-002808-84np9brx	208	3	specialized	specialized	JJ
cord-002808-84np9brx	208	4	immunofluorescence	immunofluorescence	NN
cord-002808-84np9brx	208	5	protocol	protocol	NN
cord-002808-84np9brx	208	6	for	for	IN
cord-002808-84np9brx	208	7	sequential	sequential	JJ
cord-002808-84np9brx	208	8	fluorophore	fluorophore	NN
cord-002808-84np9brx	208	9	-	-	HYPH
cord-002808-84np9brx	208	10	azide	azide	NN
cord-002808-84np9brx	208	11	conjugation	conjugation	NN
cord-002808-84np9brx	208	12	of	of	IN
cord-002808-84np9brx	208	13	EdU	edu	NN
cord-002808-84np9brx	208	14	-	-	HYPH
cord-002808-84np9brx	208	15	labeled	label	VBN
cord-002808-84np9brx	208	16	vDNA	vdna	RB
cord-002808-84np9brx	208	17	in	in	IN
cord-002808-84np9brx	208	18	differentially	differentially	RB
cord-002808-84np9brx	208	19	permeabilized	permeabilize	VBN
cord-002808-84np9brx	208	20	cells	cell	NNS
cord-002808-84np9brx	208	21	,	,	,
cord-002808-84np9brx	208	22	the	the	DT
cord-002808-84np9brx	208	23	Sapp	Sapp	NNP
cord-002808-84np9brx	208	24	laboratory	laboratory	NN
cord-002808-84np9brx	208	25	concluded	conclude	VBD
cord-002808-84np9brx	208	26	that	that	IN
cord-002808-84np9brx	208	27	vDNA	vdna	RB
cord-002808-84np9brx	208	28	became	become	VBD
cord-002808-84np9brx	208	29	cytosolic	cytosolic	JJ
cord-002808-84np9brx	208	30	sometime	sometime	RB
cord-002808-84np9brx	208	31	during	during	IN
cord-002808-84np9brx	208	32	G1	G1	NNP
cord-002808-84np9brx	208	33	,	,	,
cord-002808-84np9brx	208	34	well	well	RB
cord-002808-84np9brx	208	35	after	after	IN
cord-002808-84np9brx	208	36	mitosis	mitosis	NN
cord-002808-84np9brx	208	37	[	[	-LRB-
cord-002808-84np9brx	208	38	81	81	CD
cord-002808-84np9brx	208	39	]	]	-RRB-
cord-002808-84np9brx	208	40	.	.	.
cord-002808-84np9brx	209	1	In	in	IN
cord-002808-84np9brx	209	2	this	this	DT
cord-002808-84np9brx	209	3	model	model	NN
cord-002808-84np9brx	209	4	,	,	,
cord-002808-84np9brx	209	5	L2	L2	NNP
cord-002808-84np9brx	209	6	/	/	SYM
cord-002808-84np9brx	209	7	vDNA	vdna	RB
cord-002808-84np9brx	209	8	would	would	MD
cord-002808-84np9brx	209	9	reside	reside	VB
cord-002808-84np9brx	209	10	within	within	IN
cord-002808-84np9brx	209	11	these	these	DT
cord-002808-84np9brx	209	12	unique	unique	JJ
cord-002808-84np9brx	209	13	mitotic	mitotic	JJ
cord-002808-84np9brx	209	14	transport	transport	NN
cord-002808-84np9brx	209	15	vesicles	vesicle	NNS
cord-002808-84np9brx	209	16	,	,	,
cord-002808-84np9brx	209	17	bound	bind	VBN
cord-002808-84np9brx	209	18	to	to	IN
cord-002808-84np9brx	209	19	chromosomes	chromosome	NNS
cord-002808-84np9brx	209	20	for	for	IN
cord-002808-84np9brx	209	21	an	an	DT
cord-002808-84np9brx	209	22	extended	extended	JJ
cord-002808-84np9brx	209	23	period	period	NN
cord-002808-84np9brx	209	24	of	of	IN
cord-002808-84np9brx	209	25	time	time	NN
cord-002808-84np9brx	209	26	(	(	-LRB-
cord-002808-84np9brx	209	27	Figure	figure	NN
cord-002808-84np9brx	209	28	3	3	CD
cord-002808-84np9brx	209	29	)	)	-RRB-
cord-002808-84np9brx	209	30	,	,	,
cord-002808-84np9brx	209	31	until	until	IN
cord-002808-84np9brx	209	32	translocation	translocation	NN
cord-002808-84np9brx	209	33	occurred	occur	VBD
cord-002808-84np9brx	209	34	sometime	sometime	RB
cord-002808-84np9brx	209	35	in	in	IN
cord-002808-84np9brx	209	36	G1	G1	NNP
cord-002808-84np9brx	209	37	after	after	IN
cord-002808-84np9brx	209	38	completion	completion	NN
cord-002808-84np9brx	209	39	of	of	IN
cord-002808-84np9brx	209	40	mitosis	mitosis	NN
cord-002808-84np9brx	209	41	.	.	.
cord-002808-84np9brx	210	1	To	to	TO
cord-002808-84np9brx	210	2	better	better	RB
cord-002808-84np9brx	210	3	understand	understand	VB
cord-002808-84np9brx	210	4	translocation	translocation	NN
cord-002808-84np9brx	210	5	,	,	,
cord-002808-84np9brx	210	6	my	-PRON-	PRP$
cord-002808-84np9brx	210	7	laboratory	laboratory	NN
cord-002808-84np9brx	210	8	has	have	VBZ
cord-002808-84np9brx	210	9	developed	develop	VBN
cord-002808-84np9brx	210	10	an	an	DT
cord-002808-84np9brx	210	11	alternative	alternative	JJ
cord-002808-84np9brx	210	12	platform	platform	NN
cord-002808-84np9brx	210	13	to	to	TO
cord-002808-84np9brx	210	14	detect	detect	VB
cord-002808-84np9brx	210	15	and	and	CC
cord-002808-84np9brx	210	16	measure	measure	VB
cord-002808-84np9brx	210	17	this	this	DT
cord-002808-84np9brx	210	18	elusive	elusive	JJ
cord-002808-84np9brx	210	19	process	process	NN
cord-002808-84np9brx	210	20	.	.	.
cord-002808-84np9brx	211	1	Our	-PRON-	PRP$
cord-002808-84np9brx	211	2	system	system	NN
cord-002808-84np9brx	211	3	is	be	VBZ
cord-002808-84np9brx	211	4	based	base	VBN
cord-002808-84np9brx	211	5	on	on	IN
cord-002808-84np9brx	211	6	the	the	DT
cord-002808-84np9brx	211	7	biotin	biotin	NN
cord-002808-84np9brx	211	8	-	-	HYPH
cord-002808-84np9brx	211	9	protein	protein	NN
cord-002808-84np9brx	211	10	ligase	ligase	NN
cord-002808-84np9brx	211	11	BirA	BirA	NNP
cord-002808-84np9brx	211	12	,	,	,
cord-002808-84np9brx	211	13	from	from	IN
cord-002808-84np9brx	211	14	Escherichia	Escherichia	NNP
cord-002808-84np9brx	211	15	coli	coli	NNS
cord-002808-84np9brx	211	16	.	.	.
cord-002808-84np9brx	212	1	The	the	DT
cord-002808-84np9brx	212	2	BirA	BirA	NNP
cord-002808-84np9brx	212	3	enzyme	enzyme	NN
cord-002808-84np9brx	212	4	will	will	MD
cord-002808-84np9brx	212	5	covalently	covalently	RB
cord-002808-84np9brx	212	6	attach	attach	VB
cord-002808-84np9brx	212	7	a	a	DT
cord-002808-84np9brx	212	8	biotin	biotin	NN
cord-002808-84np9brx	212	9	molecule	molecule	NN
cord-002808-84np9brx	212	10	to	to	IN
cord-002808-84np9brx	212	11	a	a	DT
cord-002808-84np9brx	212	12	specific	specific	JJ
cord-002808-84np9brx	212	13	lysine	lysine	NN
cord-002808-84np9brx	212	14	residue	residue	NN
cord-002808-84np9brx	212	15	of	of	IN
cord-002808-84np9brx	212	16	a	a	DT
cord-002808-84np9brx	212	17	short	short	JJ
cord-002808-84np9brx	212	18	peptide	peptide	NN
cord-002808-84np9brx	212	19	substrate	substrate	NN
cord-002808-84np9brx	212	20	,	,	,
cord-002808-84np9brx	212	21	termed	term	VBD
cord-002808-84np9brx	212	22	the	the	DT
cord-002808-84np9brx	212	23	biotin	biotin	NN
cord-002808-84np9brx	212	24	acceptor	acceptor	NN
cord-002808-84np9brx	212	25	peptide	peptide	NN
cord-002808-84np9brx	212	26	(	(	-LRB-
cord-002808-84np9brx	212	27	BAP	BAP	NNP
cord-002808-84np9brx	212	28	)	)	-RRB-
cord-002808-84np9brx	212	29	.	.	.
cord-002808-84np9brx	213	1	The	the	DT
cord-002808-84np9brx	213	2	BAP	BAP	NNP
cord-002808-84np9brx	213	3	is	be	VBZ
cord-002808-84np9brx	213	4	a	a	DT
cord-002808-84np9brx	213	5	specific	specific	JJ
cord-002808-84np9brx	213	6	substrate	substrate	NN
cord-002808-84np9brx	213	7	for	for	IN
cord-002808-84np9brx	213	8	bacterial	bacterial	JJ
cord-002808-84np9brx	213	9	BirA	BirA	NNS
cord-002808-84np9brx	213	10	,	,	,
cord-002808-84np9brx	213	11	and	and	CC
cord-002808-84np9brx	213	12	is	be	VBZ
cord-002808-84np9brx	213	13	not	not	RB
cord-002808-84np9brx	213	14	recognized	recognize	VBN
cord-002808-84np9brx	213	15	by	by	IN
cord-002808-84np9brx	213	16	mammalian	mammalian	JJ
cord-002808-84np9brx	213	17	biotin	biotin	NN
cord-002808-84np9brx	213	18	-	-	HYPH
cord-002808-84np9brx	213	19	protein	protein	NN
cord-002808-84np9brx	213	20	ligases	ligase	NNS
cord-002808-84np9brx	213	21	[	[	-LRB-
cord-002808-84np9brx	213	22	51	51	CD
cord-002808-84np9brx	213	23	,	,	,
cord-002808-84np9brx	213	24	105	105	CD
cord-002808-84np9brx	213	25	]	]	-RRB-
cord-002808-84np9brx	213	26	.	.	.
cord-002808-84np9brx	214	1	By	by	IN
cord-002808-84np9brx	214	2	generating	generate	VBG
cord-002808-84np9brx	214	3	HPV	HPV	NNP
cord-002808-84np9brx	214	4	pseudoviruses	pseudoviruse	NNS
cord-002808-84np9brx	214	5	that	that	WDT
cord-002808-84np9brx	214	6	encapsidate	encapsidate	NNP
cord-002808-84np9brx	214	7	a	a	DT
cord-002808-84np9brx	214	8	functional	functional	JJ
cord-002808-84np9brx	214	9	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	214	10	fusion	fusion	NN
cord-002808-84np9brx	214	11	and	and	CC
cord-002808-84np9brx	214	12	a	a	DT
cord-002808-84np9brx	214	13	HaCaT	HaCaT	NNP
cord-002808-84np9brx	214	14	keratinocyte	keratinocyte	JJ
cord-002808-84np9brx	214	15	line	line	NN
cord-002808-84np9brx	214	16	that	that	WDT
cord-002808-84np9brx	214	17	stably	stably	RB
cord-002808-84np9brx	214	18	expresses	express	VBZ
cord-002808-84np9brx	214	19	a	a	DT
cord-002808-84np9brx	214	20	cytosolic	cytosolic	JJ
cord-002808-84np9brx	214	21	GFP	GFP	NNP
cord-002808-84np9brx	214	22	-	-	HYPH
cord-002808-84np9brx	214	23	BAP	BAP	NNP
cord-002808-84np9brx	214	24	fusion	fusion	NN
cord-002808-84np9brx	214	25	,	,	,
cord-002808-84np9brx	214	26	we	-PRON-	PRP
cord-002808-84np9brx	214	27	have	have	VBP
cord-002808-84np9brx	214	28	set	set	VBN
cord-002808-84np9brx	214	29	up	up	RP
cord-002808-84np9brx	214	30	a	a	DT
cord-002808-84np9brx	214	31	two	two	CD
cord-002808-84np9brx	214	32	-	-	HYPH
cord-002808-84np9brx	214	33	component	component	NN
cord-002808-84np9brx	214	34	compartmentalization	compartmentalization	NN
cord-002808-84np9brx	214	35	assay	assay	NN
cord-002808-84np9brx	214	36	to	to	TO
cord-002808-84np9brx	214	37	detect	detect	VB
cord-002808-84np9brx	214	38	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	214	39	translocation	translocation	NN
cord-002808-84np9brx	214	40	.	.	.
cord-002808-84np9brx	215	1	In	in	IN
cord-002808-84np9brx	215	2	this	this	DT
cord-002808-84np9brx	215	3	system	system	NN
cord-002808-84np9brx	215	4	,	,	,
cord-002808-84np9brx	215	5	lumenal	lumenal	NNP
cord-002808-84np9brx	215	6	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	215	7	is	be	VBZ
cord-002808-84np9brx	215	8	separated	separate	VBN
cord-002808-84np9brx	215	9	from	from	IN
cord-002808-84np9brx	215	10	the	the	DT
cord-002808-84np9brx	215	11	cytosolic	cytosolic	JJ
cord-002808-84np9brx	215	12	GFP	GFP	NNP
cord-002808-84np9brx	215	13	-	-	HYPH
cord-002808-84np9brx	215	14	BAP	BAP	NNP
cord-002808-84np9brx	215	15	substrate	substrate	NN
cord-002808-84np9brx	215	16	by	by	IN
cord-002808-84np9brx	215	17	limiting	limit	VBG
cord-002808-84np9brx	215	18	membranes	membrane	NNS
cord-002808-84np9brx	215	19	.	.	.
cord-002808-84np9brx	216	1	Only	only	RB
cord-002808-84np9brx	216	2	upon	upon	IN
cord-002808-84np9brx	216	3	translocation	translocation	NN
cord-002808-84np9brx	216	4	of	of	IN
cord-002808-84np9brx	216	5	L2	L2	NNP
cord-002808-84np9brx	216	6	will	will	MD
cord-002808-84np9brx	216	7	BirA	BirA	NNP
cord-002808-84np9brx	216	8	encounter	encounter	VB
cord-002808-84np9brx	216	9	the	the	DT
cord-002808-84np9brx	216	10	BAP	BAP	NNP
cord-002808-84np9brx	216	11	;	;	:
cord-002808-84np9brx	216	12	thus	thus	RB
cord-002808-84np9brx	216	13	,	,	,
cord-002808-84np9brx	216	14	biotinylation	biotinylation	NN
cord-002808-84np9brx	216	15	of	of	IN
cord-002808-84np9brx	216	16	GFP	GFP	NNP
cord-002808-84np9brx	216	17	-	-	HYPH
cord-002808-84np9brx	216	18	BAP	BAP	NNP
cord-002808-84np9brx	216	19	is	be	VBZ
cord-002808-84np9brx	216	20	a	a	DT
cord-002808-84np9brx	216	21	readout	readout	NN
cord-002808-84np9brx	216	22	for	for	IN
cord-002808-84np9brx	216	23	translocation	translocation	NN
cord-002808-84np9brx	216	24	.	.	.
cord-002808-84np9brx	217	1	However	however	RB
cord-002808-84np9brx	217	2	,	,	,
cord-002808-84np9brx	217	3	it	-PRON-	PRP
cord-002808-84np9brx	217	4	should	should	MD
cord-002808-84np9brx	217	5	be	be	VB
cord-002808-84np9brx	217	6	noted	note	VBN
cord-002808-84np9brx	217	7	that	that	IN
cord-002808-84np9brx	217	8	,	,	,
cord-002808-84np9brx	217	9	Using	use	VBG
cord-002808-84np9brx	217	10	this	this	DT
cord-002808-84np9brx	217	11	system	system	NN
cord-002808-84np9brx	217	12	,	,	,
cord-002808-84np9brx	217	13	we	-PRON-	PRP
cord-002808-84np9brx	217	14	found	find	VBD
cord-002808-84np9brx	217	15	that	that	IN
cord-002808-84np9brx	217	16	L2	L2	NNP
cord-002808-84np9brx	217	17	translocation	translocation	NN
cord-002808-84np9brx	217	18	required	require	VBD
cord-002808-84np9brx	217	19	TGN	TGN	NNP
cord-002808-84np9brx	217	20	localization	localization	NN
cord-002808-84np9brx	217	21	of	of	IN
cord-002808-84np9brx	217	22	L2	l2	NN
cord-002808-84np9brx	217	23	/	/	SYM
cord-002808-84np9brx	217	24	vDNA	vdna	NN
cord-002808-84np9brx	217	25	and	and	CC
cord-002808-84np9brx	217	26	cell	cell	NN
cord-002808-84np9brx	217	27	cycle	cycle	NN
cord-002808-84np9brx	217	28	progression	progression	NN
cord-002808-84np9brx	217	29	past	past	IN
cord-002808-84np9brx	217	30	G2	G2	NNP
cord-002808-84np9brx	217	31	/	/	SYM
cord-002808-84np9brx	217	32	M.	M.	NNP
cord-002808-84np9brx	217	33	Timecourse	Timecourse	NNP
cord-002808-84np9brx	217	34	experiments	experiment	NNS
cord-002808-84np9brx	217	35	with	with	IN
cord-002808-84np9brx	217	36	synchronized	synchronize	VBN
cord-002808-84np9brx	217	37	HaCaT	HaCaT	NNP
cord-002808-84np9brx	217	38	-	-	HYPH
cord-002808-84np9brx	217	39	GFP	GFP	NNP
cord-002808-84np9brx	217	40	-	-	HYPH
cord-002808-84np9brx	217	41	BAP	BAP	NNP
cord-002808-84np9brx	217	42	cells	cell	NNS
cord-002808-84np9brx	217	43	demonstrated	demonstrate	VBD
cord-002808-84np9brx	217	44	that	that	IN
cord-002808-84np9brx	217	45	the	the	DT
cord-002808-84np9brx	217	46	earliest	early	JJS
cord-002808-84np9brx	217	47	biotinylated	biotinylate	VBN
cord-002808-84np9brx	217	48	GFP	GFP	NNP
cord-002808-84np9brx	217	49	-	-	HYPH
cord-002808-84np9brx	217	50	BAP	BAP	NNP
cord-002808-84np9brx	217	51	signal	signal	NN
cord-002808-84np9brx	217	52	was	be	VBD
cord-002808-84np9brx	217	53	detected	detect	VBN
cord-002808-84np9brx	217	54	at	at	IN
cord-002808-84np9brx	217	55	or	or	CC
cord-002808-84np9brx	217	56	just	just	RB
cord-002808-84np9brx	217	57	prior	prior	RB
cord-002808-84np9brx	217	58	to	to	IN
cord-002808-84np9brx	217	59	the	the	DT
cord-002808-84np9brx	217	60	onset	onset	NN
cord-002808-84np9brx	217	61	of	of	IN
cord-002808-84np9brx	217	62	mitosis	mitosis	NN
cord-002808-84np9brx	217	63	.	.	.
cord-002808-84np9brx	218	1	Although	although	IN
cord-002808-84np9brx	218	2	these	these	DT
cord-002808-84np9brx	218	3	experiments	experiment	NNS
cord-002808-84np9brx	218	4	were	be	VBD
cord-002808-84np9brx	218	5	performed	perform	VBN
cord-002808-84np9brx	218	6	with	with	IN
cord-002808-84np9brx	218	7	a	a	DT
cord-002808-84np9brx	218	8	bulk	bulk	JJ
cord-002808-84np9brx	218	9	population	population	NN
cord-002808-84np9brx	218	10	,	,	,
cord-002808-84np9brx	218	11	we	-PRON-	PRP
cord-002808-84np9brx	218	12	believe	believe	VBP
cord-002808-84np9brx	218	13	it	-PRON-	PRP
cord-002808-84np9brx	218	14	suggests	suggest	VBZ
cord-002808-84np9brx	218	15	that	that	IN
cord-002808-84np9brx	218	16	L2	L2	NNP
cord-002808-84np9brx	218	17	translocation	translocation	NN
cord-002808-84np9brx	218	18	(	(	-LRB-
cord-002808-84np9brx	218	19	or	or	CC
cord-002808-84np9brx	218	20	at	at	IN
cord-002808-84np9brx	218	21	least	least	JJS
cord-002808-84np9brx	218	22	of	of	IN
cord-002808-84np9brx	218	23	the	the	DT
cord-002808-84np9brx	218	24	C	c	NN
cord-002808-84np9brx	218	25	-	-	HYPH
cord-002808-84np9brx	218	26	terminus	terminus	NN
cord-002808-84np9brx	218	27	of	of	IN
cord-002808-84np9brx	218	28	L2	L2	NNP
cord-002808-84np9brx	218	29	)	)	-RRB-
cord-002808-84np9brx	218	30	begins	begin	VBZ
cord-002808-84np9brx	218	31	during	during	IN
cord-002808-84np9brx	218	32	mitosis	mitosis	NN
cord-002808-84np9brx	218	33	(	(	-LRB-
cord-002808-84np9brx	218	34	Figure	figure	NN
cord-002808-84np9brx	218	35	3	3	CD
cord-002808-84np9brx	218	36	)	)	-RRB-
cord-002808-84np9brx	218	37	,	,	,
cord-002808-84np9brx	218	38	well	well	RB
cord-002808-84np9brx	218	39	before	before	IN
cord-002808-84np9brx	218	40	transition	transition	NN
cord-002808-84np9brx	218	41	into	into	IN
cord-002808-84np9brx	218	42	G1	G1	NNP
cord-002808-84np9brx	218	43	.	.	.
cord-002808-84np9brx	219	1	Moreover	moreover	RB
cord-002808-84np9brx	219	2	,	,	,
cord-002808-84np9brx	219	3	this	this	DT
cord-002808-84np9brx	219	4	timing	timing	NN
cord-002808-84np9brx	219	5	of	of	IN
cord-002808-84np9brx	219	6	L2	l2	NN
cord-002808-84np9brx	219	7	/	/	,
cord-002808-84np9brx	219	8	vDNA	vdna	NN
cord-002808-84np9brx	219	9	translocation	translocation	NN
cord-002808-84np9brx	219	10	would	would	MD
cord-002808-84np9brx	219	11	be	be	VB
cord-002808-84np9brx	219	12	consistent	consistent	JJ
cord-002808-84np9brx	219	13	with	with	IN
cord-002808-84np9brx	219	14	the	the	DT
cord-002808-84np9brx	219	15	visual	visual	JJ
cord-002808-84np9brx	219	16	"	"	``
cord-002808-84np9brx	219	17	jump	jump	NN
cord-002808-84np9brx	219	18	"	"	''
cord-002808-84np9brx	219	19	of	of	IN
cord-002808-84np9brx	219	20	vDNA	vdna	DT
cord-002808-84np9brx	219	21	from	from	IN
cord-002808-84np9brx	219	22	a	a	DT
cord-002808-84np9brx	219	23	punctate	punctate	NN
cord-002808-84np9brx	219	24	pericentriolar	pericentriolar	NNP
cord-002808-84np9brx	219	25	distribution	distribution	NN
cord-002808-84np9brx	219	26	in	in	IN
cord-002808-84np9brx	219	27	prometaphase	prometaphase	NN
cord-002808-84np9brx	219	28	to	to	IN
cord-002808-84np9brx	219	29	being	be	VBG
cord-002808-84np9brx	219	30	chromosome	chromosome	NN
cord-002808-84np9brx	219	31	-	-	HYPH
cord-002808-84np9brx	219	32	bound	bind	VBN
cord-002808-84np9brx	219	33	by	by	IN
cord-002808-84np9brx	219	34	metaphase	metaphase	NN
cord-002808-84np9brx	219	35	[	[	-LRB-
cord-002808-84np9brx	219	36	51	51	CD
cord-002808-84np9brx	219	37	]	]	-RRB-
cord-002808-84np9brx	219	38	.	.	.
cord-002808-84np9brx	220	1	The	the	DT
cord-002808-84np9brx	220	2	chromosome	chromosome	NN
cord-002808-84np9brx	220	3	binding	bind	VBG
cord-002808-84np9brx	220	4	ability	ability	NN
cord-002808-84np9brx	220	5	of	of	IN
cord-002808-84np9brx	220	6	L2	L2	NNP
cord-002808-84np9brx	220	7	was	be	VBD
cord-002808-84np9brx	220	8	first	first	RB
cord-002808-84np9brx	220	9	reported	report	VBN
cord-002808-84np9brx	220	10	in	in	IN
cord-002808-84np9brx	220	11	2014	2014	CD
cord-002808-84np9brx	220	12	[	[	-LRB-
cord-002808-84np9brx	220	13	50	50	CD
cord-002808-84np9brx	220	14	]	]	-RRB-
cord-002808-84np9brx	220	15	,	,	,
cord-002808-84np9brx	220	16	and	and	CC
cord-002808-84np9brx	220	17	since	since	IN
cord-002808-84np9brx	220	18	then	then	RB
cord-002808-84np9brx	220	19	,	,	,
cord-002808-84np9brx	220	20	the	the	DT
cord-002808-84np9brx	220	21	Schelhaas	Schelhaas	NNP
cord-002808-84np9brx	220	22	group	group	NN
cord-002808-84np9brx	220	23	has	have	VBZ
cord-002808-84np9brx	220	24	mapped	map	VBN
cord-002808-84np9brx	220	25	a	a	DT
cord-002808-84np9brx	220	26	minimal	minimal	JJ
cord-002808-84np9brx	220	27	chromatin	chromatin	NN
cord-002808-84np9brx	220	28	binding	bind	VBG
cord-002808-84np9brx	220	29	region	region	NN
cord-002808-84np9brx	220	30	(	(	-LRB-
cord-002808-84np9brx	220	31	CBR	CBR	NNP
cord-002808-84np9brx	220	32	,	,	,
cord-002808-84np9brx	220	33	residues	residue	VBZ
cord-002808-84np9brx	220	34	188	188	CD
cord-002808-84np9brx	220	35	-	-	SYM
cord-002808-84np9brx	220	36	334	334	CD
cord-002808-84np9brx	220	37	for	for	IN
cord-002808-84np9brx	220	38	HPV16	hpv16	ADD
cord-002808-84np9brx	220	39	)	)	-RRB-
cord-002808-84np9brx	220	40	within	within	IN
cord-002808-84np9brx	220	41	L2	L2	NNP
cord-002808-84np9brx	220	42	[	[	-LRB-
cord-002808-84np9brx	220	43	49	49	CD
cord-002808-84np9brx	220	44	]	]	-RRB-
cord-002808-84np9brx	220	45	.	.	.
cord-002808-84np9brx	221	1	Interestingly	interestingly	RB
cord-002808-84np9brx	221	2	,	,	,
cord-002808-84np9brx	221	3	the	the	DT
cord-002808-84np9brx	221	4	ability	ability	NN
cord-002808-84np9brx	221	5	of	of	IN
cord-002808-84np9brx	221	6	ectopically	ectopically	RB
cord-002808-84np9brx	221	7	expressed	express	VBN
cord-002808-84np9brx	221	8	L2-GFP	L2-GFP	NNP
cord-002808-84np9brx	221	9	fusion	fusion	NN
cord-002808-84np9brx	221	10	to	to	TO
cord-002808-84np9brx	221	11	associate	associate	VB
cord-002808-84np9brx	221	12	with	with	IN
cord-002808-84np9brx	221	13	mitotic	mitotic	JJ
cord-002808-84np9brx	221	14	chromatin	chromatin	NN
cord-002808-84np9brx	221	15	was	be	VBD
cord-002808-84np9brx	221	16	found	find	VBN
cord-002808-84np9brx	221	17	to	to	TO
cord-002808-84np9brx	221	18	require	require	VB
cord-002808-84np9brx	221	19	cell	cell	NN
cord-002808-84np9brx	221	20	cycle	cycle	NN
cord-002808-84np9brx	221	21	progression	progression	NN
cord-002808-84np9brx	221	22	into	into	IN
cord-002808-84np9brx	221	23	prometaphase	prometaphase	NN
cord-002808-84np9brx	221	24	.	.	.
cord-002808-84np9brx	222	1	This	this	DT
cord-002808-84np9brx	222	2	finding	finding	NN
cord-002808-84np9brx	222	3	is	be	VBZ
cord-002808-84np9brx	222	4	suggestive	suggestive	JJ
cord-002808-84np9brx	222	5	that	that	IN
cord-002808-84np9brx	222	6	either	either	CC
cord-002808-84np9brx	222	7	the	the	DT
cord-002808-84np9brx	222	8	interaction	interaction	NN
cord-002808-84np9brx	222	9	between	between	IN
cord-002808-84np9brx	222	10	L2	l2	NN
cord-002808-84np9brx	222	11	and	and	CC
cord-002808-84np9brx	222	12	mitotic	mitotic	JJ
cord-002808-84np9brx	222	13	chromatin	chromatin	NN
cord-002808-84np9brx	222	14	is	be	VBZ
cord-002808-84np9brx	222	15	indirect	indirect	JJ
cord-002808-84np9brx	222	16	,	,	,
cord-002808-84np9brx	222	17	requiring	require	VBG
cord-002808-84np9brx	222	18	a	a	DT
cord-002808-84np9brx	222	19	prometaphase	prometaphase	JJ
cord-002808-84np9brx	222	20	-	-	HYPH
cord-002808-84np9brx	222	21	specific	specific	JJ
cord-002808-84np9brx	222	22	factor	factor	NN
cord-002808-84np9brx	222	23	,	,	,
cord-002808-84np9brx	222	24	or	or	CC
cord-002808-84np9brx	222	25	that	that	IN
cord-002808-84np9brx	222	26	L2	L2	NNP
cord-002808-84np9brx	222	27	is	be	VBZ
cord-002808-84np9brx	222	28	post	post	JJ
cord-002808-84np9brx	222	29	-	-	JJ
cord-002808-84np9brx	222	30	translationally	translationally	RB
cord-002808-84np9brx	222	31	modified	modify	VBN
cord-002808-84np9brx	222	32	during	during	IN
cord-002808-84np9brx	222	33	prometaphase	prometaphase	NN
cord-002808-84np9brx	222	34	to	to	TO
cord-002808-84np9brx	222	35	somehow	somehow	RB
cord-002808-84np9brx	222	36	activate	activate	VB
cord-002808-84np9brx	222	37	its	-PRON-	PRP$
cord-002808-84np9brx	222	38	chromatin	chromatin	NN
cord-002808-84np9brx	222	39	binding	bind	VBG
cord-002808-84np9brx	222	40	ability	ability	NN
cord-002808-84np9brx	222	41	.	.	.
cord-002808-84np9brx	223	1	Substitution	substitution	NN
cord-002808-84np9brx	223	2	of	of	IN
cord-002808-84np9brx	223	3	specific	specific	JJ
cord-002808-84np9brx	223	4	residues	residue	NNS
cord-002808-84np9brx	223	5	(	(	-LRB-
cord-002808-84np9brx	223	6	IVAL	IVAL	NNP
cord-002808-84np9brx	223	7	;	;	:
cord-002808-84np9brx	223	8	286	286	CD
cord-002808-84np9brx	223	9	-	-	SYM
cord-002808-84np9brx	223	10	289	289	CD
cord-002808-84np9brx	223	11	,	,	,
cord-002808-84np9brx	223	12	R302/305	R302/305	NNP
cord-002808-84np9brx	223	13	,	,	,
cord-002808-84np9brx	223	14	and	and	CC
cord-002808-84np9brx	223	15	RTR	RTR	NNP
cord-002808-84np9brx	223	16	;	;	:
cord-002808-84np9brx	223	17	313	313	CD
cord-002808-84np9brx	223	18	-	-	SYM
cord-002808-84np9brx	223	19	315	315	CD
cord-002808-84np9brx	223	20	)	)	-RRB-
cord-002808-84np9brx	223	21	were	be	VBD
cord-002808-84np9brx	223	22	found	find	VBN
cord-002808-84np9brx	223	23	to	to	TO
cord-002808-84np9brx	223	24	completely	completely	RB
cord-002808-84np9brx	223	25	abrogate	abrogate	VB
cord-002808-84np9brx	223	26	the	the	DT
cord-002808-84np9brx	223	27	chromatin	chromatin	NN
cord-002808-84np9brx	223	28	binding	bind	VBG
cord-002808-84np9brx	223	29	activity	activity	NN
cord-002808-84np9brx	223	30	while	while	IN
cord-002808-84np9brx	223	31	mutation	mutation	NN
cord-002808-84np9brx	223	32	of	of	IN
cord-002808-84np9brx	223	33	RR396/397	rr396/397	NN
cord-002808-84np9brx	223	34	resulted	result	VBD
cord-002808-84np9brx	223	35	in	in	IN
cord-002808-84np9brx	223	36	a	a	DT
cord-002808-84np9brx	223	37	partial	partial	JJ
cord-002808-84np9brx	223	38	-	-	HYPH
cord-002808-84np9brx	223	39	inhibition	inhibition	NN
cord-002808-84np9brx	223	40	CBR	CBR	NNP
cord-002808-84np9brx	223	41	function	function	NN
cord-002808-84np9brx	223	42	.	.	.
cord-002808-84np9brx	224	1	When	when	WRB
cord-002808-84np9brx	224	2	these	these	DT
cord-002808-84np9brx	224	3	same	same	JJ
cord-002808-84np9brx	224	4	residues	residue	NNS
cord-002808-84np9brx	224	5	were	be	VBD
cord-002808-84np9brx	224	6	mutated	mutate	VBN
cord-002808-84np9brx	224	7	in	in	IN
cord-002808-84np9brx	224	8	reporter	reporter	NN
cord-002808-84np9brx	224	9	-	-	HYPH
cord-002808-84np9brx	224	10	expressing	express	VBG
cord-002808-84np9brx	224	11	PsV	psv	NN
cord-002808-84np9brx	224	12	,	,	,
cord-002808-84np9brx	224	13	packaged	package	VBN
cord-002808-84np9brx	224	14	with	with	IN
cord-002808-84np9brx	224	15	either	either	CC
cord-002808-84np9brx	224	16	L2	L2	NNP
cord-002808-84np9brx	224	17	or	or	CC
cord-002808-84np9brx	224	18	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	224	19	,	,	,
cord-002808-84np9brx	224	20	the	the	DT
cord-002808-84np9brx	224	21	same	same	JJ
cord-002808-84np9brx	224	22	phenotypes	phenotype	NNS
cord-002808-84np9brx	224	23	were	be	VBD
cord-002808-84np9brx	224	24	Upon	upon	IN
cord-002808-84np9brx	224	25	entry	entry	NN
cord-002808-84np9brx	224	26	into	into	IN
cord-002808-84np9brx	224	27	mitosis	mitosis	NN
cord-002808-84np9brx	224	28	,	,	,
cord-002808-84np9brx	224	29	L2	L2	NNP
cord-002808-84np9brx	224	30	/	/	SYM
cord-002808-84np9brx	224	31	vDNA	vdna	RB
cord-002808-84np9brx	224	32	remains	remain	VBZ
cord-002808-84np9brx	224	33	vesicle	vesicle	NN
cord-002808-84np9brx	224	34	-	-	HYPH
cord-002808-84np9brx	224	35	bound	bind	VBN
cord-002808-84np9brx	224	36	but	but	CC
cord-002808-84np9brx	224	37	loses	lose	VBZ
cord-002808-84np9brx	224	38	coincidence	coincidence	NN
cord-002808-84np9brx	224	39	with	with	IN
cord-002808-84np9brx	224	40	TGN	TGN	NNP
cord-002808-84np9brx	224	41	markers	marker	NNS
cord-002808-84np9brx	224	42	.	.	.
cord-002808-84np9brx	225	1	These	these	DT
cord-002808-84np9brx	225	2	L2	L2	NNP
cord-002808-84np9brx	225	3	/	/	SYM
cord-002808-84np9brx	225	4	vDNA	vdna	RB
cord-002808-84np9brx	225	5	-	-	HYPH
cord-002808-84np9brx	225	6	containing	contain	VBG
cord-002808-84np9brx	225	7	vesicles	vesicle	NNS
cord-002808-84np9brx	225	8	likely	likely	RB
cord-002808-84np9brx	225	9	travel	travel	VBP
cord-002808-84np9brx	225	10	along	along	IN
cord-002808-84np9brx	225	11	astral	astral	JJ
cord-002808-84np9brx	225	12	microtubules	microtubule	NNS
cord-002808-84np9brx	225	13	in	in	IN
cord-002808-84np9brx	225	14	the	the	DT
cord-002808-84np9brx	225	15	minus	minus	JJ
cord-002808-84np9brx	225	16	-	-	HYPH
cord-002808-84np9brx	225	17	end	end	NN
cord-002808-84np9brx	225	18	direction	direction	NN
cord-002808-84np9brx	225	19	towards	towards	IN
cord-002808-84np9brx	225	20	the	the	DT
cord-002808-84np9brx	225	21	centrosome	centrosome	NN
cord-002808-84np9brx	225	22	,	,	,
cord-002808-84np9brx	225	23	where	where	WRB
cord-002808-84np9brx	225	24	they	-PRON-	PRP
cord-002808-84np9brx	225	25	accumulate	accumulate	VBP
cord-002808-84np9brx	225	26	during	during	IN
cord-002808-84np9brx	225	27	prometaphase	prometaphase	NN
cord-002808-84np9brx	225	28	.	.	.
cord-002808-84np9brx	226	1	The	the	DT
cord-002808-84np9brx	226	2	vesicles	vesicle	NNS
cord-002808-84np9brx	226	3	likely	likely	RB
cord-002808-84np9brx	226	4	switch	switch	VBP
cord-002808-84np9brx	226	5	polarity	polarity	NN
cord-002808-84np9brx	226	6	and	and	CC
cord-002808-84np9brx	226	7	travel	travel	NN
cord-002808-84np9brx	226	8	along	along	IN
cord-002808-84np9brx	226	9	the	the	DT
cord-002808-84np9brx	226	10	spindle	spindle	NN
cord-002808-84np9brx	226	11	microtubules	microtubule	NNS
cord-002808-84np9brx	226	12	in	in	IN
cord-002808-84np9brx	226	13	the	the	DT
cord-002808-84np9brx	226	14	plus	plus	JJ
cord-002808-84np9brx	226	15	-	-	HYPH
cord-002808-84np9brx	226	16	end	end	NN
cord-002808-84np9brx	226	17	direction	direction	NN
cord-002808-84np9brx	226	18	to	to	TO
cord-002808-84np9brx	226	19	reach	reach	VB
cord-002808-84np9brx	226	20	the	the	DT
cord-002808-84np9brx	226	21	host	host	NN
cord-002808-84np9brx	226	22	chromosomes	chromosome	NNS
cord-002808-84np9brx	226	23	by	by	IN
cord-002808-84np9brx	226	24	metaphase	metaphase	NN
cord-002808-84np9brx	226	25	.	.	.
cord-002808-84np9brx	227	1	Chromosome	chromosome	NN
cord-002808-84np9brx	227	2	-	-	HYPH
cord-002808-84np9brx	227	3	bound	bind	VBN
cord-002808-84np9brx	227	4	L2	L2	NNP
cord-002808-84np9brx	227	5	/	/	,
cord-002808-84np9brx	227	6	vDNA	vdna	NN
cord-002808-84np9brx	227	7	partitions	partition	NNS
cord-002808-84np9brx	227	8	with	with	IN
cord-002808-84np9brx	227	9	host	host	NN
cord-002808-84np9brx	227	10	chromosomes	chromosome	NNS
cord-002808-84np9brx	227	11	,	,	,
cord-002808-84np9brx	227	12	eventually	eventually	RB
cord-002808-84np9brx	227	13	localizing	localize	VBG
cord-002808-84np9brx	227	14	to	to	IN
cord-002808-84np9brx	227	15	PML	PML	NNP
cord-002808-84np9brx	227	16	bodies	body	NNS
cord-002808-84np9brx	227	17	of	of	IN
cord-002808-84np9brx	227	18	the	the	DT
cord-002808-84np9brx	227	19	daughter	daughter	NN
cord-002808-84np9brx	227	20	cells	cell	NNS
cord-002808-84np9brx	227	21	.	.	.
cord-002808-84np9brx	228	1	Chromosome	chromosome	NN
cord-002808-84np9brx	228	2	binding	binding	NN
cord-002808-84np9brx	228	3	of	of	IN
cord-002808-84np9brx	228	4	L2	l2	NN
cord-002808-84np9brx	228	5	/	/	,
cord-002808-84np9brx	228	6	vDNA	vdna	RB
cord-002808-84np9brx	228	7	is	be	VBZ
cord-002808-84np9brx	228	8	through	through	IN
cord-002808-84np9brx	228	9	the	the	DT
cord-002808-84np9brx	228	10	chromatin	chromatin	NN
cord-002808-84np9brx	228	11	binding	bind	VBG
cord-002808-84np9brx	228	12	region	region	NN
cord-002808-84np9brx	228	13	(	(	-LRB-
cord-002808-84np9brx	228	14	CBR	CBR	NNP
cord-002808-84np9brx	228	15	)	)	-RRB-
cord-002808-84np9brx	228	16	of	of	IN
cord-002808-84np9brx	228	17	L2	L2	NNP
cord-002808-84np9brx	228	18	and	and	CC
cord-002808-84np9brx	228	19	mutation	mutation	NN
cord-002808-84np9brx	228	20	of	of	IN
cord-002808-84np9brx	228	21	this	this	DT
cord-002808-84np9brx	228	22	region	region	NN
cord-002808-84np9brx	228	23	causes	cause	VBZ
cord-002808-84np9brx	228	24	a	a	DT
cord-002808-84np9brx	228	25	block	block	NN
cord-002808-84np9brx	228	26	in	in	IN
cord-002808-84np9brx	228	27	translocation	translocation	NN
cord-002808-84np9brx	228	28	,	,	,
cord-002808-84np9brx	228	29	with	with	IN
cord-002808-84np9brx	228	30	vesicular	vesicular	JJ
cord-002808-84np9brx	228	31	L2	L2	NNP
cord-002808-84np9brx	228	32	/	/	,
cord-002808-84np9brx	228	33	vDNA	vdna	RB
cord-002808-84np9brx	228	34	becoming	become	VBG
cord-002808-84np9brx	228	35	reabsorbed	reabsorb	VBN
cord-002808-84np9brx	228	36	back	back	RB
cord-002808-84np9brx	228	37	into	into	IN
cord-002808-84np9brx	228	38	the	the	DT
cord-002808-84np9brx	228	39	nascent	nascent	JJ
cord-002808-84np9brx	228	40	Golgi	Golgi	NNP
cord-002808-84np9brx	228	41	after	after	IN
cord-002808-84np9brx	228	42	mitosis	mitosis	NN
cord-002808-84np9brx	228	43	.	.	.
cord-002808-84np9brx	229	1	Chromosome	chromosome	NN
cord-002808-84np9brx	229	2	-	-	HYPH
cord-002808-84np9brx	229	3	bound	bind	VBN
cord-002808-84np9brx	229	4	L2	l2	NN
cord-002808-84np9brx	229	5	/	/	,
cord-002808-84np9brx	229	6	vDNA	vdna	NN
cord-002808-84np9brx	229	7	may	may	MD
cord-002808-84np9brx	229	8	be	be	VB
cord-002808-84np9brx	229	9	in	in	IN
cord-002808-84np9brx	229	10	a	a	DT
cord-002808-84np9brx	229	11	membrane	membrane	NN
cord-002808-84np9brx	229	12	-	-	HYPH
cord-002808-84np9brx	229	13	bound	bind	VBN
cord-002808-84np9brx	229	14	vesiclular	vesiclular	JJ
cord-002808-84np9brx	229	15	state	state	NN
cord-002808-84np9brx	229	16	,	,	,
cord-002808-84np9brx	229	17	or	or	CC
cord-002808-84np9brx	229	18	may	may	MD
cord-002808-84np9brx	229	19	have	have	VB
cord-002808-84np9brx	229	20	penetrated	penetrate	VBN
cord-002808-84np9brx	229	21	the	the	DT
cord-002808-84np9brx	229	22	limiting	limit	VBG
cord-002808-84np9brx	229	23	membrane	membrane	NN
cord-002808-84np9brx	229	24	upon	upon	IN
cord-002808-84np9brx	229	25	chromosome	chromosome	NN
cord-002808-84np9brx	229	26	binding	binding	NN
cord-002808-84np9brx	229	27	,	,	,
cord-002808-84np9brx	229	28	further	further	JJ
cord-002808-84np9brx	229	29	work	work	NN
cord-002808-84np9brx	229	30	is	be	VBZ
cord-002808-84np9brx	229	31	needed	need	VBN
cord-002808-84np9brx	229	32	to	to	TO
cord-002808-84np9brx	229	33	clarify	clarify	VB
cord-002808-84np9brx	229	34	this	this	DT
cord-002808-84np9brx	229	35	stage	stage	NN
cord-002808-84np9brx	229	36	of	of	IN
cord-002808-84np9brx	229	37	the	the	DT
cord-002808-84np9brx	229	38	HPV	HPV	NNP
cord-002808-84np9brx	229	39	life	life	NN
cord-002808-84np9brx	229	40	cycle	cycle	NN
cord-002808-84np9brx	229	41	.	.	.
cord-002808-84np9brx	230	1	Using	use	VBG
cord-002808-84np9brx	230	2	this	this	DT
cord-002808-84np9brx	230	3	system	system	NN
cord-002808-84np9brx	230	4	,	,	,
cord-002808-84np9brx	230	5	we	-PRON-	PRP
cord-002808-84np9brx	230	6	found	find	VBD
cord-002808-84np9brx	230	7	that	that	IN
cord-002808-84np9brx	230	8	L2	L2	NNP
cord-002808-84np9brx	230	9	translocation	translocation	NN
cord-002808-84np9brx	230	10	required	require	VBD
cord-002808-84np9brx	230	11	TGN	TGN	NNP
cord-002808-84np9brx	230	12	localization	localization	NN
cord-002808-84np9brx	230	13	of	of	IN
cord-002808-84np9brx	230	14	L2	l2	NN
cord-002808-84np9brx	230	15	/	/	SYM
cord-002808-84np9brx	230	16	vDNA	vdna	NN
cord-002808-84np9brx	230	17	and	and	CC
cord-002808-84np9brx	230	18	cell	cell	NN
cord-002808-84np9brx	230	19	cycle	cycle	NN
cord-002808-84np9brx	230	20	progression	progression	NN
cord-002808-84np9brx	230	21	past	past	IN
cord-002808-84np9brx	230	22	G2	G2	NNP
cord-002808-84np9brx	230	23	/	/	SYM
cord-002808-84np9brx	230	24	M.	M.	NNP
cord-002808-84np9brx	230	25	Timecourse	Timecourse	NNP
cord-002808-84np9brx	230	26	experiments	experiment	NNS
cord-002808-84np9brx	230	27	with	with	IN
cord-002808-84np9brx	230	28	synchronized	synchronize	VBN
cord-002808-84np9brx	230	29	HaCaT	HaCaT	NNP
cord-002808-84np9brx	230	30	-	-	HYPH
cord-002808-84np9brx	230	31	GFP	GFP	NNP
cord-002808-84np9brx	230	32	-	-	HYPH
cord-002808-84np9brx	230	33	BAP	BAP	NNP
cord-002808-84np9brx	230	34	cells	cell	NNS
cord-002808-84np9brx	230	35	demonstrated	demonstrate	VBD
cord-002808-84np9brx	230	36	that	that	IN
cord-002808-84np9brx	230	37	the	the	DT
cord-002808-84np9brx	230	38	earliest	early	JJS
cord-002808-84np9brx	230	39	biotinylated	biotinylate	VBN
cord-002808-84np9brx	230	40	GFP	GFP	NNP
cord-002808-84np9brx	230	41	-	-	HYPH
cord-002808-84np9brx	230	42	BAP	BAP	NNP
cord-002808-84np9brx	230	43	signal	signal	NN
cord-002808-84np9brx	230	44	was	be	VBD
cord-002808-84np9brx	230	45	detected	detect	VBN
cord-002808-84np9brx	230	46	at	at	IN
cord-002808-84np9brx	230	47	or	or	CC
cord-002808-84np9brx	230	48	just	just	RB
cord-002808-84np9brx	230	49	prior	prior	RB
cord-002808-84np9brx	230	50	to	to	IN
cord-002808-84np9brx	230	51	the	the	DT
cord-002808-84np9brx	230	52	onset	onset	NN
cord-002808-84np9brx	230	53	of	of	IN
cord-002808-84np9brx	230	54	mitosis	mitosis	NN
cord-002808-84np9brx	230	55	.	.	.
cord-002808-84np9brx	231	1	Although	although	IN
cord-002808-84np9brx	231	2	these	these	DT
cord-002808-84np9brx	231	3	experiments	experiment	NNS
cord-002808-84np9brx	231	4	were	be	VBD
cord-002808-84np9brx	231	5	performed	perform	VBN
cord-002808-84np9brx	231	6	with	with	IN
cord-002808-84np9brx	231	7	a	a	DT
cord-002808-84np9brx	231	8	bulk	bulk	JJ
cord-002808-84np9brx	231	9	population	population	NN
cord-002808-84np9brx	231	10	,	,	,
cord-002808-84np9brx	231	11	we	-PRON-	PRP
cord-002808-84np9brx	231	12	believe	believe	VBP
cord-002808-84np9brx	231	13	it	-PRON-	PRP
cord-002808-84np9brx	231	14	suggests	suggest	VBZ
cord-002808-84np9brx	231	15	that	that	IN
cord-002808-84np9brx	231	16	L2	L2	NNP
cord-002808-84np9brx	231	17	translocation	translocation	NN
cord-002808-84np9brx	231	18	(	(	-LRB-
cord-002808-84np9brx	231	19	or	or	CC
cord-002808-84np9brx	231	20	at	at	IN
cord-002808-84np9brx	231	21	least	least	JJS
cord-002808-84np9brx	231	22	of	of	IN
cord-002808-84np9brx	231	23	the	the	DT
cord-002808-84np9brx	231	24	C	c	NN
cord-002808-84np9brx	231	25	-	-	HYPH
cord-002808-84np9brx	231	26	terminus	terminus	NN
cord-002808-84np9brx	231	27	of	of	IN
cord-002808-84np9brx	231	28	L2	L2	NNP
cord-002808-84np9brx	231	29	)	)	-RRB-
cord-002808-84np9brx	231	30	begins	begin	VBZ
cord-002808-84np9brx	231	31	during	during	IN
cord-002808-84np9brx	231	32	mitosis	mitosis	NN
cord-002808-84np9brx	231	33	(	(	-LRB-
cord-002808-84np9brx	231	34	Figure	figure	NN
cord-002808-84np9brx	231	35	3	3	CD
cord-002808-84np9brx	231	36	)	)	-RRB-
cord-002808-84np9brx	231	37	,	,	,
cord-002808-84np9brx	231	38	well	well	RB
cord-002808-84np9brx	231	39	before	before	IN
cord-002808-84np9brx	231	40	transition	transition	NN
cord-002808-84np9brx	231	41	into	into	IN
cord-002808-84np9brx	231	42	G1	G1	NNP
cord-002808-84np9brx	231	43	.	.	.
cord-002808-84np9brx	232	1	Moreover	moreover	RB
cord-002808-84np9brx	232	2	,	,	,
cord-002808-84np9brx	232	3	this	this	DT
cord-002808-84np9brx	232	4	timing	timing	NN
cord-002808-84np9brx	232	5	of	of	IN
cord-002808-84np9brx	232	6	L2	l2	NN
cord-002808-84np9brx	232	7	/	/	,
cord-002808-84np9brx	232	8	vDNA	vdna	NN
cord-002808-84np9brx	232	9	translocation	translocation	NN
cord-002808-84np9brx	232	10	would	would	MD
cord-002808-84np9brx	232	11	be	be	VB
cord-002808-84np9brx	232	12	consistent	consistent	JJ
cord-002808-84np9brx	232	13	with	with	IN
cord-002808-84np9brx	232	14	the	the	DT
cord-002808-84np9brx	232	15	visual	visual	JJ
cord-002808-84np9brx	232	16	"	"	``
cord-002808-84np9brx	232	17	jump	jump	NN
cord-002808-84np9brx	232	18	"	"	''
cord-002808-84np9brx	232	19	of	of	IN
cord-002808-84np9brx	232	20	vDNA	vdna	DT
cord-002808-84np9brx	232	21	from	from	IN
cord-002808-84np9brx	232	22	a	a	DT
cord-002808-84np9brx	232	23	punctate	punctate	NN
cord-002808-84np9brx	232	24	pericentriolar	pericentriolar	NNP
cord-002808-84np9brx	232	25	distribution	distribution	NN
cord-002808-84np9brx	232	26	in	in	IN
cord-002808-84np9brx	232	27	prometaphase	prometaphase	NN
cord-002808-84np9brx	232	28	to	to	IN
cord-002808-84np9brx	232	29	being	be	VBG
cord-002808-84np9brx	232	30	chromosome	chromosome	NN
cord-002808-84np9brx	232	31	-	-	HYPH
cord-002808-84np9brx	232	32	bound	bind	VBN
cord-002808-84np9brx	232	33	by	by	IN
cord-002808-84np9brx	232	34	metaphase	metaphase	NN
cord-002808-84np9brx	232	35	[	[	-LRB-
cord-002808-84np9brx	232	36	51	51	CD
cord-002808-84np9brx	232	37	]	]	-RRB-
cord-002808-84np9brx	232	38	.	.	.
cord-002808-84np9brx	233	1	The	the	DT
cord-002808-84np9brx	233	2	chromosome	chromosome	NN
cord-002808-84np9brx	233	3	binding	bind	VBG
cord-002808-84np9brx	233	4	ability	ability	NN
cord-002808-84np9brx	233	5	of	of	IN
cord-002808-84np9brx	233	6	L2	L2	NNP
cord-002808-84np9brx	233	7	was	be	VBD
cord-002808-84np9brx	233	8	first	first	RB
cord-002808-84np9brx	233	9	reported	report	VBN
cord-002808-84np9brx	233	10	in	in	IN
cord-002808-84np9brx	233	11	2014	2014	CD
cord-002808-84np9brx	233	12	[	[	-LRB-
cord-002808-84np9brx	233	13	50	50	CD
cord-002808-84np9brx	233	14	]	]	-RRB-
cord-002808-84np9brx	233	15	,	,	,
cord-002808-84np9brx	233	16	and	and	CC
cord-002808-84np9brx	233	17	since	since	IN
cord-002808-84np9brx	233	18	then	then	RB
cord-002808-84np9brx	233	19	,	,	,
cord-002808-84np9brx	233	20	the	the	DT
cord-002808-84np9brx	233	21	Schelhaas	Schelhaas	NNP
cord-002808-84np9brx	233	22	group	group	NN
cord-002808-84np9brx	233	23	has	have	VBZ
cord-002808-84np9brx	233	24	mapped	map	VBN
cord-002808-84np9brx	233	25	a	a	DT
cord-002808-84np9brx	233	26	minimal	minimal	JJ
cord-002808-84np9brx	233	27	chromatin	chromatin	NN
cord-002808-84np9brx	233	28	binding	bind	VBG
cord-002808-84np9brx	233	29	region	region	NN
cord-002808-84np9brx	233	30	(	(	-LRB-
cord-002808-84np9brx	233	31	CBR	CBR	NNP
cord-002808-84np9brx	233	32	,	,	,
cord-002808-84np9brx	233	33	residues	residue	VBZ
cord-002808-84np9brx	233	34	188	188	CD
cord-002808-84np9brx	233	35	-	-	SYM
cord-002808-84np9brx	233	36	334	334	CD
cord-002808-84np9brx	233	37	for	for	IN
cord-002808-84np9brx	233	38	HPV16	hpv16	ADD
cord-002808-84np9brx	233	39	)	)	-RRB-
cord-002808-84np9brx	233	40	within	within	IN
cord-002808-84np9brx	233	41	L2	L2	NNP
cord-002808-84np9brx	233	42	[	[	-LRB-
cord-002808-84np9brx	233	43	49	49	CD
cord-002808-84np9brx	233	44	]	]	-RRB-
cord-002808-84np9brx	233	45	.	.	.
cord-002808-84np9brx	234	1	Interestingly	interestingly	RB
cord-002808-84np9brx	234	2	,	,	,
cord-002808-84np9brx	234	3	the	the	DT
cord-002808-84np9brx	234	4	ability	ability	NN
cord-002808-84np9brx	234	5	of	of	IN
cord-002808-84np9brx	234	6	ectopically	ectopically	RB
cord-002808-84np9brx	234	7	expressed	express	VBN
cord-002808-84np9brx	234	8	L2-GFP	L2-GFP	NNP
cord-002808-84np9brx	234	9	fusion	fusion	NN
cord-002808-84np9brx	234	10	to	to	TO
cord-002808-84np9brx	234	11	associate	associate	VB
cord-002808-84np9brx	234	12	with	with	IN
cord-002808-84np9brx	234	13	mitotic	mitotic	JJ
cord-002808-84np9brx	234	14	chromatin	chromatin	NN
cord-002808-84np9brx	234	15	was	be	VBD
cord-002808-84np9brx	234	16	found	find	VBN
cord-002808-84np9brx	234	17	to	to	TO
cord-002808-84np9brx	234	18	require	require	VB
cord-002808-84np9brx	234	19	cell	cell	NN
cord-002808-84np9brx	234	20	cycle	cycle	NN
cord-002808-84np9brx	234	21	progression	progression	NN
cord-002808-84np9brx	234	22	into	into	IN
cord-002808-84np9brx	234	23	prometaphase	prometaphase	NN
cord-002808-84np9brx	234	24	.	.	.
cord-002808-84np9brx	235	1	This	this	DT
cord-002808-84np9brx	235	2	finding	finding	NN
cord-002808-84np9brx	235	3	is	be	VBZ
cord-002808-84np9brx	235	4	suggestive	suggestive	JJ
cord-002808-84np9brx	235	5	that	that	IN
cord-002808-84np9brx	235	6	either	either	CC
cord-002808-84np9brx	235	7	the	the	DT
cord-002808-84np9brx	235	8	interaction	interaction	NN
cord-002808-84np9brx	235	9	between	between	IN
cord-002808-84np9brx	235	10	L2	l2	NN
cord-002808-84np9brx	235	11	and	and	CC
cord-002808-84np9brx	235	12	mitotic	mitotic	JJ
cord-002808-84np9brx	235	13	chromatin	chromatin	NN
cord-002808-84np9brx	235	14	is	be	VBZ
cord-002808-84np9brx	235	15	indirect	indirect	JJ
cord-002808-84np9brx	235	16	,	,	,
cord-002808-84np9brx	235	17	requiring	require	VBG
cord-002808-84np9brx	235	18	a	a	DT
cord-002808-84np9brx	235	19	prometaphase	prometaphase	JJ
cord-002808-84np9brx	235	20	-	-	HYPH
cord-002808-84np9brx	235	21	specific	specific	JJ
cord-002808-84np9brx	235	22	factor	factor	NN
cord-002808-84np9brx	235	23	,	,	,
cord-002808-84np9brx	235	24	or	or	CC
cord-002808-84np9brx	235	25	that	that	IN
cord-002808-84np9brx	235	26	L2	L2	NNP
cord-002808-84np9brx	235	27	is	be	VBZ
cord-002808-84np9brx	235	28	post	post	JJ
cord-002808-84np9brx	235	29	-	-	JJ
cord-002808-84np9brx	235	30	translationally	translationally	RB
cord-002808-84np9brx	235	31	modified	modify	VBN
cord-002808-84np9brx	235	32	during	during	IN
cord-002808-84np9brx	235	33	prometaphase	prometaphase	NN
cord-002808-84np9brx	235	34	to	to	TO
cord-002808-84np9brx	235	35	somehow	somehow	RB
cord-002808-84np9brx	235	36	activate	activate	VB
cord-002808-84np9brx	235	37	its	-PRON-	PRP$
cord-002808-84np9brx	235	38	chromatin	chromatin	NN
cord-002808-84np9brx	235	39	binding	bind	VBG
cord-002808-84np9brx	235	40	ability	ability	NN
cord-002808-84np9brx	235	41	.	.	.
cord-002808-84np9brx	236	1	Substitution	substitution	NN
cord-002808-84np9brx	236	2	of	of	IN
cord-002808-84np9brx	236	3	specific	specific	JJ
cord-002808-84np9brx	236	4	residues	residue	NNS
cord-002808-84np9brx	236	5	(	(	-LRB-
cord-002808-84np9brx	236	6	IVAL	IVAL	NNP
cord-002808-84np9brx	236	7	;	;	:
cord-002808-84np9brx	236	8	286	286	CD
cord-002808-84np9brx	236	9	-	-	SYM
cord-002808-84np9brx	236	10	289	289	CD
cord-002808-84np9brx	236	11	,	,	,
cord-002808-84np9brx	236	12	R302/305	R302/305	NNP
cord-002808-84np9brx	236	13	,	,	,
cord-002808-84np9brx	236	14	and	and	CC
cord-002808-84np9brx	236	15	RTR	RTR	NNP
cord-002808-84np9brx	236	16	;	;	:
cord-002808-84np9brx	236	17	313	313	CD
cord-002808-84np9brx	236	18	-	-	SYM
cord-002808-84np9brx	236	19	315	315	CD
cord-002808-84np9brx	236	20	)	)	-RRB-
cord-002808-84np9brx	236	21	were	be	VBD
cord-002808-84np9brx	236	22	found	find	VBN
cord-002808-84np9brx	236	23	to	to	TO
cord-002808-84np9brx	236	24	completely	completely	RB
cord-002808-84np9brx	236	25	abrogate	abrogate	VB
cord-002808-84np9brx	236	26	the	the	DT
cord-002808-84np9brx	236	27	chromatin	chromatin	NN
cord-002808-84np9brx	236	28	binding	bind	VBG
cord-002808-84np9brx	236	29	activity	activity	NN
cord-002808-84np9brx	236	30	while	while	IN
cord-002808-84np9brx	236	31	mutation	mutation	NN
cord-002808-84np9brx	236	32	of	of	IN
cord-002808-84np9brx	236	33	RR396/397	rr396/397	NN
cord-002808-84np9brx	236	34	resulted	result	VBD
cord-002808-84np9brx	236	35	in	in	IN
cord-002808-84np9brx	236	36	a	a	DT
cord-002808-84np9brx	236	37	partial	partial	JJ
cord-002808-84np9brx	236	38	-	-	HYPH
cord-002808-84np9brx	236	39	inhibition	inhibition	NN
cord-002808-84np9brx	236	40	CBR	CBR	NNP
cord-002808-84np9brx	236	41	function	function	NN
cord-002808-84np9brx	236	42	.	.	.
cord-002808-84np9brx	237	1	When	when	WRB
cord-002808-84np9brx	237	2	these	these	DT
cord-002808-84np9brx	237	3	same	same	JJ
cord-002808-84np9brx	237	4	residues	residue	NNS
cord-002808-84np9brx	237	5	were	be	VBD
cord-002808-84np9brx	237	6	mutated	mutate	VBN
cord-002808-84np9brx	237	7	in	in	IN
cord-002808-84np9brx	237	8	reporter	reporter	NN
cord-002808-84np9brx	237	9	-	-	HYPH
cord-002808-84np9brx	237	10	expressing	express	VBG
cord-002808-84np9brx	237	11	PsV	psv	NN
cord-002808-84np9brx	237	12	,	,	,
cord-002808-84np9brx	237	13	packaged	package	VBN
cord-002808-84np9brx	237	14	with	with	IN
cord-002808-84np9brx	237	15	either	either	CC
cord-002808-84np9brx	237	16	L2	L2	NNP
cord-002808-84np9brx	237	17	or	or	CC
cord-002808-84np9brx	237	18	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	237	19	,	,	,
cord-002808-84np9brx	237	20	the	the	DT
cord-002808-84np9brx	237	21	same	same	JJ
cord-002808-84np9brx	237	22	phenotypes	phenotype	NNS
cord-002808-84np9brx	237	23	were	be	VBD
cord-002808-84np9brx	237	24	observed	observe	VBN
cord-002808-84np9brx	237	25	-	-	:
cord-002808-84np9brx	237	26	infectivity	infectivity	NN
cord-002808-84np9brx	237	27	and	and	CC
cord-002808-84np9brx	237	28	translocation	translocation	NN
cord-002808-84np9brx	237	29	were	be	VBD
cord-002808-84np9brx	237	30	completely	completely	RB
cord-002808-84np9brx	237	31	blocked	block	VBN
cord-002808-84np9brx	237	32	for	for	IN
cord-002808-84np9brx	237	33	IVAL	IVAL	NNP
cord-002808-84np9brx	237	34	;	;	:
cord-002808-84np9brx	237	35	286	286	CD
cord-002808-84np9brx	237	36	-	-	SYM
cord-002808-84np9brx	237	37	289	289	CD
cord-002808-84np9brx	237	38	,	,	,
cord-002808-84np9brx	237	39	R302/305	R302/305	NNP
cord-002808-84np9brx	237	40	,	,	,
cord-002808-84np9brx	237	41	and	and	CC
cord-002808-84np9brx	237	42	RTR	RTR	NNP
cord-002808-84np9brx	237	43	;	;	:
cord-002808-84np9brx	237	44	313	313	CD
cord-002808-84np9brx	237	45	-	-	SYM
cord-002808-84np9brx	237	46	315	315	CD
cord-002808-84np9brx	237	47	and	and	CC
cord-002808-84np9brx	237	48	partially	partially	RB
cord-002808-84np9brx	237	49	blocked	block	VBN
cord-002808-84np9brx	237	50	for	for	IN
cord-002808-84np9brx	237	51	RR396/397	rr396/397	NN
cord-002808-84np9brx	237	52	[	[	-LRB-
cord-002808-84np9brx	237	53	49	49	CD
cord-002808-84np9brx	237	54	,	,	,
cord-002808-84np9brx	237	55	51	51	CD
cord-002808-84np9brx	237	56	]	]	-RRB-
cord-002808-84np9brx	237	57	.	.	.
cord-002808-84np9brx	238	1	The	the	DT
cord-002808-84np9brx	238	2	striking	striking	JJ
cord-002808-84np9brx	238	3	correlation	correlation	NN
cord-002808-84np9brx	238	4	between	between	IN
cord-002808-84np9brx	238	5	the	the	DT
cord-002808-84np9brx	238	6	ability	ability	NN
cord-002808-84np9brx	238	7	of	of	IN
cord-002808-84np9brx	238	8	L2	L2	NNP
cord-002808-84np9brx	238	9	to	to	TO
cord-002808-84np9brx	238	10	bind	bind	VB
cord-002808-84np9brx	238	11	chromatin	chromatin	NN
cord-002808-84np9brx	238	12	and	and	CC
cord-002808-84np9brx	238	13	to	to	TO
cord-002808-84np9brx	238	14	translocate	translocate	VB
cord-002808-84np9brx	238	15	during	during	IN
cord-002808-84np9brx	238	16	infection	infection	NN
cord-002808-84np9brx	238	17	supports	support	VBZ
cord-002808-84np9brx	238	18	a	a	DT
cord-002808-84np9brx	238	19	model	model	NN
cord-002808-84np9brx	238	20	whereby	whereby	WRB
cord-002808-84np9brx	238	21	chromatin	chromatin	NN
cord-002808-84np9brx	238	22	binding	binding	NN
cord-002808-84np9brx	238	23	is	be	VBZ
cord-002808-84np9brx	238	24	required	require	VBN
cord-002808-84np9brx	238	25	for	for	IN
cord-002808-84np9brx	238	26	L2	l2	NN
cord-002808-84np9brx	238	27	translocation	translocation	NN
cord-002808-84np9brx	238	28	[	[	-LRB-
cord-002808-84np9brx	238	29	49	49	CD
cord-002808-84np9brx	238	30	,	,	,
cord-002808-84np9brx	238	31	51	51	CD
cord-002808-84np9brx	238	32	]	]	-RRB-
cord-002808-84np9brx	238	33	.	.	.
cord-002808-84np9brx	239	1	A	a	DT
cord-002808-84np9brx	239	2	mechanistic	mechanistic	JJ
cord-002808-84np9brx	239	3	linkage	linkage	NN
cord-002808-84np9brx	239	4	between	between	IN
cord-002808-84np9brx	239	5	these	these	DT
cord-002808-84np9brx	239	6	processes	process	NNS
cord-002808-84np9brx	239	7	favors	favor	VBZ
cord-002808-84np9brx	239	8	a	a	DT
cord-002808-84np9brx	239	9	model	model	NN
cord-002808-84np9brx	239	10	where	where	WRB
cord-002808-84np9brx	239	11	translocation	translocation	NN
cord-002808-84np9brx	239	12	of	of	IN
cord-002808-84np9brx	239	13	L2	L2	NNP
cord-002808-84np9brx	239	14	/	/	SYM
cord-002808-84np9brx	239	15	vDNA	vdna	NN
cord-002808-84np9brx	239	16	out	out	IN
cord-002808-84np9brx	239	17	of	of	IN
cord-002808-84np9brx	239	18	the	the	DT
cord-002808-84np9brx	239	19	mitotic	mitotic	JJ
cord-002808-84np9brx	239	20	vesicles	vesicle	NNS
cord-002808-84np9brx	239	21	occurs	occur	VBZ
cord-002808-84np9brx	239	22	while	while	IN
cord-002808-84np9brx	239	23	these	these	DT
cord-002808-84np9brx	239	24	compartments	compartment	NNS
cord-002808-84np9brx	239	25	encounter	encounter	VBP
cord-002808-84np9brx	239	26	mitotic	mitotic	JJ
cord-002808-84np9brx	239	27	chromosomes	chromosome	NNS
cord-002808-84np9brx	239	28	during	during	IN
cord-002808-84np9brx	239	29	prometaphase	prometaphase	NN
cord-002808-84np9brx	239	30	,	,	,
cord-002808-84np9brx	239	31	and	and	CC
cord-002808-84np9brx	239	32	is	be	VBZ
cord-002808-84np9brx	239	33	supported	support	VBN
cord-002808-84np9brx	239	34	by	by	IN
cord-002808-84np9brx	239	35	appearance	appearance	NN
cord-002808-84np9brx	239	36	of	of	IN
cord-002808-84np9brx	239	37	translocation	translocation	NN
cord-002808-84np9brx	239	38	signal	signal	NN
cord-002808-84np9brx	239	39	in	in	IN
cord-002808-84np9brx	239	40	timecourse	timecourse	NN
cord-002808-84np9brx	239	41	experiments	experiment	NNS
cord-002808-84np9brx	239	42	[	[	-LRB-
cord-002808-84np9brx	239	43	51	51	CD
cord-002808-84np9brx	239	44	]	]	-RRB-
cord-002808-84np9brx	239	45	.	.	.
cord-002808-84np9brx	240	1	While	while	IN
cord-002808-84np9brx	240	2	further	further	JJ
cord-002808-84np9brx	240	3	work	work	NN
cord-002808-84np9brx	240	4	is	be	VBZ
cord-002808-84np9brx	240	5	needed	need	VBN
cord-002808-84np9brx	240	6	to	to	TO
cord-002808-84np9brx	240	7	validate	validate	VB
cord-002808-84np9brx	240	8	one	one	CD
cord-002808-84np9brx	240	9	model	model	NN
cord-002808-84np9brx	240	10	over	over	IN
cord-002808-84np9brx	240	11	another	another	DT
cord-002808-84np9brx	240	12	,	,	,
cord-002808-84np9brx	240	13	it	-PRON-	PRP
cord-002808-84np9brx	240	14	should	should	MD
cord-002808-84np9brx	240	15	be	be	VB
cord-002808-84np9brx	240	16	noted	note	VBN
cord-002808-84np9brx	240	17	that	that	IN
cord-002808-84np9brx	240	18	the	the	DT
cord-002808-84np9brx	240	19	two	two	CD
cord-002808-84np9brx	240	20	models	model	NNS
cord-002808-84np9brx	240	21	do	do	VBP
cord-002808-84np9brx	240	22	not	not	RB
cord-002808-84np9brx	240	23	have	have	VB
cord-002808-84np9brx	240	24	to	to	TO
cord-002808-84np9brx	240	25	be	be	VB
cord-002808-84np9brx	240	26	mutually	mutually	RB
cord-002808-84np9brx	240	27	exclusive	exclusive	JJ
cord-002808-84np9brx	240	28	.	.	.
cord-002808-84np9brx	241	1	Translocation	Translocation	NNP
cord-002808-84np9brx	241	2	studies	study	NNS
cord-002808-84np9brx	241	3	based	base	VBN
cord-002808-84np9brx	241	4	on	on	IN
cord-002808-84np9brx	241	5	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	241	6	may	may	MD
cord-002808-84np9brx	241	7	in	in	IN
cord-002808-84np9brx	241	8	fact	fact	NN
cord-002808-84np9brx	241	9	only	only	RB
cord-002808-84np9brx	241	10	be	be	VB
cord-002808-84np9brx	241	11	revealing	reveal	VBG
cord-002808-84np9brx	241	12	exposure	exposure	NN
cord-002808-84np9brx	241	13	of	of	IN
cord-002808-84np9brx	241	14	the	the	DT
cord-002808-84np9brx	241	15	L2	L2	NNP
cord-002808-84np9brx	241	16	C	C	NNP
cord-002808-84np9brx	241	17	-	-	HYPH
cord-002808-84np9brx	241	18	terminus	terminus	NN
cord-002808-84np9brx	241	19	,	,	,
cord-002808-84np9brx	241	20	and	and	CC
cord-002808-84np9brx	241	21	full	full	JJ
cord-002808-84np9brx	241	22	translocation	translocation	NN
cord-002808-84np9brx	241	23	of	of	IN
cord-002808-84np9brx	241	24	vDNA	vdna	DT
cord-002808-84np9brx	241	25	could	could	MD
cord-002808-84np9brx	241	26	be	be	VB
cord-002808-84np9brx	241	27	occurring	occur	VBG
cord-002808-84np9brx	241	28	at	at	IN
cord-002808-84np9brx	241	29	a	a	DT
cord-002808-84np9brx	241	30	later	later	JJ
cord-002808-84np9brx	241	31	time	time	NN
cord-002808-84np9brx	241	32	post	post	NN
cord-002808-84np9brx	241	33	-	-	JJ
cord-002808-84np9brx	241	34	mitosis	mitosis	JJ
cord-002808-84np9brx	241	35	,	,	,
cord-002808-84np9brx	241	36	as	as	IN
cord-002808-84np9brx	241	37	suggested	suggest	VBN
cord-002808-84np9brx	241	38	by	by	IN
cord-002808-84np9brx	241	39	the	the	DT
cord-002808-84np9brx	241	40	Sapp	Sapp	NNP
cord-002808-84np9brx	241	41	laboratory	laboratory	NN
cord-002808-84np9brx	241	42	.	.	.
cord-002808-84np9brx	242	1	Alternatively	alternatively	RB
cord-002808-84np9brx	242	2	,	,	,
cord-002808-84np9brx	242	3	the	the	DT
cord-002808-84np9brx	242	4	nature	nature	NN
cord-002808-84np9brx	242	5	of	of	IN
cord-002808-84np9brx	242	6	these	these	DT
cord-002808-84np9brx	242	7	vesicles	vesicle	NNS
cord-002808-84np9brx	242	8	is	be	VBZ
cord-002808-84np9brx	242	9	unknown	unknown	JJ
cord-002808-84np9brx	242	10	,	,	,
cord-002808-84np9brx	242	11	and	and	CC
cord-002808-84np9brx	242	12	if	if	IN
cord-002808-84np9brx	242	13	their	-PRON-	PRP$
cord-002808-84np9brx	242	14	lipid	lipid	NN
cord-002808-84np9brx	242	15	composition	composition	NN
cord-002808-84np9brx	242	16	and	and	CC
cord-002808-84np9brx	242	17	detergent	detergent	NN
cord-002808-84np9brx	242	18	solubility	solubility	NN
cord-002808-84np9brx	242	19	changes	change	NNS
cord-002808-84np9brx	242	20	during	during	IN
cord-002808-84np9brx	242	21	mitosis	mitosis	NN
cord-002808-84np9brx	242	22	,	,	,
cord-002808-84np9brx	242	23	it	-PRON-	PRP
cord-002808-84np9brx	242	24	could	could	MD
cord-002808-84np9brx	242	25	affect	affect	VB
cord-002808-84np9brx	242	26	sequential	sequential	JJ
cord-002808-84np9brx	242	27	labeling	labeling	NN
cord-002808-84np9brx	242	28	efficiency	efficiency	NN
cord-002808-84np9brx	242	29	or	or	CC
cord-002808-84np9brx	242	30	EdU	edu	NN
cord-002808-84np9brx	242	31	-	-	HYPH
cord-002808-84np9brx	242	32	labeled	label	VBN
cord-002808-84np9brx	242	33	vDNA	vdna	IN
cord-002808-84np9brx	242	34	availability	availability	NN
cord-002808-84np9brx	242	35	to	to	IN
cord-002808-84np9brx	242	36	fluorophore	fluorophore	NN
cord-002808-84np9brx	242	37	-	-	HYPH
cord-002808-84np9brx	242	38	azides	azide	NNS
cord-002808-84np9brx	242	39	after	after	IN
cord-002808-84np9brx	242	40	differential	differential	JJ
cord-002808-84np9brx	242	41	detergent	detergent	NN
cord-002808-84np9brx	242	42	permeabilization	permeabilization	NN
cord-002808-84np9brx	242	43	.	.	.
cord-002808-84np9brx	243	1	As	as	IN
cord-002808-84np9brx	243	2	mentioned	mention	VBN
cord-002808-84np9brx	243	3	above	above	RB
cord-002808-84np9brx	243	4	,	,	,
cord-002808-84np9brx	243	5	immunofluorescence	immunofluorescence	NN
cord-002808-84np9brx	243	6	staining	staining	NN
cord-002808-84np9brx	243	7	with	with	IN
cord-002808-84np9brx	243	8	mAbs	mabs	NN
cord-002808-84np9brx	243	9	specific	specific	JJ
cord-002808-84np9brx	243	10	for	for	IN
cord-002808-84np9brx	243	11	L2	L2	NNP
cord-002808-84np9brx	243	12	epitopes	epitope	NNS
cord-002808-84np9brx	243	13	flanking	flank	VBG
cord-002808-84np9brx	243	14	the	the	DT
cord-002808-84np9brx	243	15	TMD	TMD	NNP
cord-002808-84np9brx	243	16	suggest	suggest	VBP
cord-002808-84np9brx	243	17	a	a	DT
cord-002808-84np9brx	243	18	type	type	NN
cord-002808-84np9brx	243	19	-	-	:
cord-002808-84np9brx	243	20	I	-PRON-	PRP
cord-002808-84np9brx	243	21	topology	topology	NN
cord-002808-84np9brx	243	22	for	for	IN
cord-002808-84np9brx	243	23	L2	l2	NN
cord-002808-84np9brx	243	24	protrusion	protrusion	NN
cord-002808-84np9brx	243	25	,	,	,
cord-002808-84np9brx	243	26	with	with	IN
cord-002808-84np9brx	243	27	the	the	DT
cord-002808-84np9brx	243	28	N	N	NNP
cord-002808-84np9brx	243	29	-	-	HYPH
cord-002808-84np9brx	243	30	terminal~45	terminal~45	JJ
cord-002808-84np9brx	243	31	residues	residue	NNS
cord-002808-84np9brx	243	32	being	be	VBG
cord-002808-84np9brx	243	33	lumenal	lumenal	JJ
cord-002808-84np9brx	243	34	,	,	,
cord-002808-84np9brx	243	35	a~25	a~25	NN
cord-002808-84np9brx	243	36	residue	residue	NN
cord-002808-84np9brx	243	37	TMD	TMD	NNP
cord-002808-84np9brx	243	38	,	,	,
cord-002808-84np9brx	243	39	and	and	CC
cord-002808-84np9brx	243	40	the	the	DT
cord-002808-84np9brx	243	41	C	C	NNP
cord-002808-84np9brx	243	42	-	-	HYPH
cord-002808-84np9brx	243	43	terminal~400	terminal~400	NN
cord-002808-84np9brx	243	44	residues	residue	NNS
cord-002808-84np9brx	243	45	being	be	VBG
cord-002808-84np9brx	243	46	cytosolic	cytosolic	JJ
cord-002808-84np9brx	243	47	[	[	-LRB-
cord-002808-84np9brx	243	48	80	80	CD
cord-002808-84np9brx	243	49	]	]	-RRB-
cord-002808-84np9brx	244	1	(	(	-LRB-
cord-002808-84np9brx	244	2	Figure	figure	NN
cord-002808-84np9brx	244	3	4	4	CD
cord-002808-84np9brx	244	4	)	)	-RRB-
cord-002808-84np9brx	244	5	.	.	.
cord-002808-84np9brx	245	1	This	this	DT
cord-002808-84np9brx	245	2	topology	topology	NN
cord-002808-84np9brx	245	3	is	be	VBZ
cord-002808-84np9brx	245	4	in	in	IN
cord-002808-84np9brx	245	5	agreement	agreement	NN
cord-002808-84np9brx	245	6	with	with	IN
cord-002808-84np9brx	245	7	the	the	DT
cord-002808-84np9brx	245	8	placement	placement	NN
cord-002808-84np9brx	245	9	of	of	IN
cord-002808-84np9brx	245	10	known	know	VBN
cord-002808-84np9brx	245	11	SNX17	SNX17	NNP
cord-002808-84np9brx	245	12	and	and	CC
cord-002808-84np9brx	245	13	retromer	retromer	NN
cord-002808-84np9brx	245	14	binding	binding	NN
cord-002808-84np9brx	245	15	motifs	motif	NNS
cord-002808-84np9brx	245	16	within	within	IN
cord-002808-84np9brx	245	17	L2	L2	NNP
cord-002808-84np9brx	245	18	,	,	,
cord-002808-84np9brx	245	19	as	as	RB
cord-002808-84np9brx	245	20	well	well	RB
cord-002808-84np9brx	245	21	as	as	IN
cord-002808-84np9brx	245	22	the	the	DT
cord-002808-84np9brx	245	23	newly	newly	RB
cord-002808-84np9brx	245	24	defined	define	VBN
cord-002808-84np9brx	245	25	CBR	CBR	NNP
cord-002808-84np9brx	245	26	(	(	-LRB-
cord-002808-84np9brx	245	27	Figure	figure	NN
cord-002808-84np9brx	245	28	1	1	CD
cord-002808-84np9brx	245	29	)	)	-RRB-
cord-002808-84np9brx	245	30	.	.	.
cord-002808-84np9brx	246	1	However	however	RB
cord-002808-84np9brx	246	2	,	,	,
cord-002808-84np9brx	246	3	translocation	translocation	NN
cord-002808-84np9brx	246	4	studies	study	NNS
cord-002808-84np9brx	246	5	with	with	IN
cord-002808-84np9brx	246	6	PsV	psv	NN
cord-002808-84np9brx	246	7	encapsidating	encapsidate	VBG
cord-002808-84np9brx	246	8	the	the	DT
cord-002808-84np9brx	246	9	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	246	10	fusion	fusion	NN
cord-002808-84np9brx	246	11	are	be	VBP
cord-002808-84np9brx	246	12	suggestive	suggestive	JJ
cord-002808-84np9brx	246	13	of	of	IN
cord-002808-84np9brx	246	14	a	a	DT
cord-002808-84np9brx	246	15	different	different	JJ
cord-002808-84np9brx	246	16	topology	topology	NN
cord-002808-84np9brx	246	17	for	for	IN
cord-002808-84np9brx	246	18	L2	L2	NNP
cord-002808-84np9brx	246	19	.	.	.
cord-002808-84np9brx	247	1	HPV	hpv	NN
cord-002808-84np9brx	247	2	infection	infection	NN
cord-002808-84np9brx	247	3	in	in	IN
cord-002808-84np9brx	247	4	the	the	DT
cord-002808-84np9brx	247	5	presence	presence	NN
cord-002808-84np9brx	247	6	of	of	IN
cord-002808-84np9brx	247	7	S	s	NN
cord-002808-84np9brx	247	8	-	-	HYPH
cord-002808-84np9brx	247	9	phase	phase	NN
cord-002808-84np9brx	247	10	blockers	blocker	NNS
cord-002808-84np9brx	247	11	like	like	IN
cord-002808-84np9brx	247	12	aphidicolin	aphidicolin	JJ
cord-002808-84np9brx	247	13	traps	trap	NNS
cord-002808-84np9brx	248	1	incoming	incoming	JJ
cord-002808-84np9brx	248	2	L2	L2	NNP
cord-002808-84np9brx	248	3	/	/	,
cord-002808-84np9brx	248	4	vDNA	vdna	NN
cord-002808-84np9brx	248	5	at	at	IN
cord-002808-84np9brx	248	6	the	the	DT
cord-002808-84np9brx	248	7	TGN	TGN	NNP
cord-002808-84np9brx	248	8	,	,	,
cord-002808-84np9brx	248	9	likely	likely	JJ
cord-002808-84np9brx	248	10	in	in	IN
cord-002808-84np9brx	248	11	the	the	DT
cord-002808-84np9brx	248	12	protruding	protrude	VBG
cord-002808-84np9brx	248	13	conformation	conformation	NN
cord-002808-84np9brx	248	14	[	[	-LRB-
cord-002808-84np9brx	248	15	51	51	CD
cord-002808-84np9brx	248	16	]	]	-RRB-
cord-002808-84np9brx	248	17	.	.	.
cord-002808-84np9brx	249	1	This	this	DT
cord-002808-84np9brx	249	2	block	block	NN
cord-002808-84np9brx	249	3	is	be	VBZ
cord-002808-84np9brx	249	4	reversible	reversible	JJ
cord-002808-84np9brx	249	5	,	,	,
cord-002808-84np9brx	249	6	as	as	IN
cord-002808-84np9brx	249	7	removal	removal	NN
cord-002808-84np9brx	249	8	of	of	IN
cord-002808-84np9brx	249	9	the	the	DT
cord-002808-84np9brx	249	10	drug	drug	NN
cord-002808-84np9brx	249	11	releases	release	VBZ
cord-002808-84np9brx	249	12	cell	cell	NN
cord-002808-84np9brx	249	13	cycle	cycle	NN
cord-002808-84np9brx	249	14	inhibition	inhibition	NN
cord-002808-84np9brx	249	15	and	and	CC
cord-002808-84np9brx	249	16	enables	enable	VBZ
cord-002808-84np9brx	249	17	synchronized	synchronize	VBN
cord-002808-84np9brx	249	18	egress	egress	NN
cord-002808-84np9brx	249	19	and	and	CC
cord-002808-84np9brx	249	20	translocation	translocation	NN
cord-002808-84np9brx	249	21	of	of	IN
cord-002808-84np9brx	249	22	L2	L2	NNP
cord-002808-84np9brx	249	23	/	/	SYM
cord-002808-84np9brx	249	24	vDNA	vdna	NN
cord-002808-84np9brx	249	25	out	out	IN
cord-002808-84np9brx	249	26	of	of	IN
cord-002808-84np9brx	249	27	the	the	DT
cord-002808-84np9brx	249	28	TGN	TGN	NNP
cord-002808-84np9brx	249	29	upon	upon	IN
cord-002808-84np9brx	249	30	entry	entry	NN
cord-002808-84np9brx	249	31	into	into	IN
cord-002808-84np9brx	249	32	mitosis	mitosis	NN
cord-002808-84np9brx	249	33	[	[	-LRB-
cord-002808-84np9brx	249	34	51	51	CD
cord-002808-84np9brx	249	35	]	]	-RRB-
cord-002808-84np9brx	249	36	.	.	.
cord-002808-84np9brx	250	1	This	this	DT
cord-002808-84np9brx	250	2	data	data	NN
cord-002808-84np9brx	250	3	,	,	,
cord-002808-84np9brx	250	4	however	however	RB
cord-002808-84np9brx	250	5	,	,	,
cord-002808-84np9brx	250	6	is	be	VBZ
cord-002808-84np9brx	250	7	not	not	RB
cord-002808-84np9brx	250	8	in	in	IN
cord-002808-84np9brx	250	9	agreement	agreement	NN
cord-002808-84np9brx	250	10	with	with	IN
cord-002808-84np9brx	250	11	a	a	DT
cord-002808-84np9brx	250	12	strict	strict	JJ
cord-002808-84np9brx	250	13	type	type	NN
cord-002808-84np9brx	250	14	-	-	:
cord-002808-84np9brx	250	15	I	i	NN
cord-002808-84np9brx	250	16	membrane	membrane	NN
cord-002808-84np9brx	250	17	topology	topology	NN
cord-002808-84np9brx	250	18	for	for	IN
cord-002808-84np9brx	250	19	L2	L2	NNP
cord-002808-84np9brx	250	20	.	.	.
cord-002808-84np9brx	251	1	The	the	DT
cord-002808-84np9brx	251	2	lack	lack	NN
cord-002808-84np9brx	251	3	of	of	IN
cord-002808-84np9brx	251	4	translocation	translocation	NN
cord-002808-84np9brx	251	5	signal	signal	NN
cord-002808-84np9brx	251	6	in	in	IN
cord-002808-84np9brx	251	7	the	the	DT
cord-002808-84np9brx	251	8	presence	presence	NN
cord-002808-84np9brx	251	9	of	of	IN
cord-002808-84np9brx	251	10	aphidicolin	aphidicolin	NNP
cord-002808-84np9brx	251	11	implies	imply	VBZ
cord-002808-84np9brx	251	12	that	that	IN
cord-002808-84np9brx	251	13	the	the	DT
cord-002808-84np9brx	251	14	C	C	NNP
cord-002808-84np9brx	251	15	-	-	HYPH
cord-002808-84np9brx	251	16	terminus	terminus	NN
cord-002808-84np9brx	251	17	of	of	IN
cord-002808-84np9brx	251	18	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	251	19	is	be	VBZ
cord-002808-84np9brx	251	20	not	not	RB
cord-002808-84np9brx	251	21	cytosolic	cytosolic	JJ
cord-002808-84np9brx	251	22	,	,	,
cord-002808-84np9brx	251	23	as	as	IN
cord-002808-84np9brx	251	24	it	-PRON-	PRP
cord-002808-84np9brx	251	25	would	would	MD
cord-002808-84np9brx	251	26	be	be	VB
cord-002808-84np9brx	251	27	in	in	IN
cord-002808-84np9brx	251	28	a	a	DT
cord-002808-84np9brx	251	29	type	type	NN
cord-002808-84np9brx	251	30	-	-	:
cord-002808-84np9brx	251	31	I	-PRON-	PRP
cord-002808-84np9brx	251	32	topology	topology	NN
cord-002808-84np9brx	251	33	.	.	.
cord-002808-84np9brx	252	1	Rather	rather	RB
cord-002808-84np9brx	252	2	,	,	,
cord-002808-84np9brx	252	3	it	-PRON-	PRP
cord-002808-84np9brx	252	4	suggests	suggest	VBZ
cord-002808-84np9brx	252	5	that	that	IN
cord-002808-84np9brx	252	6	BirA	BirA	NNP
cord-002808-84np9brx	252	7	is	be	VBZ
cord-002808-84np9brx	252	8	either	either	CC
cord-002808-84np9brx	252	9	lumenal	lumenal	JJ
cord-002808-84np9brx	252	10	or	or	CC
cord-002808-84np9brx	252	11	is	be	VBZ
cord-002808-84np9brx	252	12	somehow	somehow	RB
cord-002808-84np9brx	252	13	obstructed	obstruct	VBN
cord-002808-84np9brx	252	14	from	from	IN
cord-002808-84np9brx	252	15	engaging	engage	VBG
cord-002808-84np9brx	252	16	the	the	DT
cord-002808-84np9brx	252	17	GFP	GFP	NNP
cord-002808-84np9brx	252	18	-	-	HYPH
cord-002808-84np9brx	252	19	BAP	BAP	NNP
cord-002808-84np9brx	252	20	substrate	substrate	NN
cord-002808-84np9brx	252	21	when	when	WRB
cord-002808-84np9brx	252	22	L2	L2	NNP
cord-002808-84np9brx	252	23	is	be	VBZ
cord-002808-84np9brx	252	24	protruding	protrude	VBG
cord-002808-84np9brx	252	25	from	from	IN
cord-002808-84np9brx	252	26	endosomal	endosomal	NNP
cord-002808-84np9brx	252	27	and	and	CC
cord-002808-84np9brx	252	28	TGN	TGN	NNP
cord-002808-84np9brx	252	29	compartments	compartment	NNS
cord-002808-84np9brx	252	30	,	,	,
cord-002808-84np9brx	252	31	only	only	RB
cord-002808-84np9brx	252	32	becoming	become	VBG
cord-002808-84np9brx	252	33	accessible	accessible	JJ
cord-002808-84np9brx	252	34	to	to	IN
cord-002808-84np9brx	252	35	the	the	DT
cord-002808-84np9brx	252	36	cytosol	cytosol	NN
cord-002808-84np9brx	252	37	upon	upon	IN
cord-002808-84np9brx	252	38	entry	entry	NN
cord-002808-84np9brx	252	39	into	into	IN
cord-002808-84np9brx	252	40	mitosis	mitosis	NN
cord-002808-84np9brx	252	41	.	.	.
cord-002808-84np9brx	253	1	A	a	DT
cord-002808-84np9brx	253	2	double	double	JJ
cord-002808-84np9brx	253	3	-	-	HYPH
cord-002808-84np9brx	253	4	pass	pass	NN
cord-002808-84np9brx	253	5	topology	topology	NN
cord-002808-84np9brx	253	6	of	of	IN
cord-002808-84np9brx	253	7	protruding	protrude	VBG
cord-002808-84np9brx	253	8	L2-BirA	L2-BirA	NNS
cord-002808-84np9brx	253	9	would	would	MD
cord-002808-84np9brx	253	10	result	result	VB
cord-002808-84np9brx	253	11	in	in	IN
cord-002808-84np9brx	253	12	a	a	DT
cord-002808-84np9brx	253	13	lumenal	lumenal	JJ
cord-002808-84np9brx	253	14	C	c	NN
cord-002808-84np9brx	253	15	-	-	HYPH
cord-002808-84np9brx	253	16	terminal	terminal	NN
cord-002808-84np9brx	253	17	BirA	BirA	NNP
cord-002808-84np9brx	253	18	(	(	-LRB-
cord-002808-84np9brx	253	19	Figure	Figure	NNP
cord-002808-84np9brx	253	20	4	4	CD
cord-002808-84np9brx	253	21	)	)	-RRB-
cord-002808-84np9brx	253	22	.	.	.
cord-002808-84np9brx	254	1	It	-PRON-	PRP
cord-002808-84np9brx	254	2	should	should	MD
cord-002808-84np9brx	254	3	be	be	VB
cord-002808-84np9brx	254	4	noted	note	VBN
cord-002808-84np9brx	254	5	that	that	IN
cord-002808-84np9brx	254	6	the	the	DT
cord-002808-84np9brx	254	7	C	C	NNP
cord-002808-84np9brx	254	8	-	-	HYPH
cord-002808-84np9brx	254	9	terminal	terminal	NN
cord-002808-84np9brx	254	10	membrane	membrane	NN
cord-002808-84np9brx	254	11	destabilization	destabilization	NN
cord-002808-84np9brx	254	12	peptide	peptide	NN
cord-002808-84np9brx	254	13	bears	bear	VBZ
cord-002808-84np9brx	254	14	no	no	DT
cord-002808-84np9brx	254	15	resemblance	resemblance	NN
cord-002808-84np9brx	254	16	to	to	IN
cord-002808-84np9brx	254	17	a	a	DT
cord-002808-84np9brx	254	18	conventional	conventional	JJ
cord-002808-84np9brx	254	19	TMD	TMD	NNP
cord-002808-84np9brx	254	20	,	,	,
cord-002808-84np9brx	254	21	and	and	CC
cord-002808-84np9brx	254	22	no	no	DT
cord-002808-84np9brx	254	23	other	other	JJ
cord-002808-84np9brx	254	24	membrane	membrane	NN
cord-002808-84np9brx	254	25	-	-	HYPH
cord-002808-84np9brx	254	26	spanning	span	VBG
cord-002808-84np9brx	254	27	regions	region	NNS
cord-002808-84np9brx	254	28	of	of	IN
cord-002808-84np9brx	254	29	L2	L2	NNP
cord-002808-84np9brx	254	30	have	have	VBP
cord-002808-84np9brx	254	31	been	be	VBN
cord-002808-84np9brx	254	32	identified	identify	VBN
cord-002808-84np9brx	254	33	,	,	,
cord-002808-84np9brx	254	34	so	so	CC
cord-002808-84np9brx	254	35	it	-PRON-	PRP
cord-002808-84np9brx	254	36	is	be	VBZ
cord-002808-84np9brx	254	37	unclear	unclear	JJ
cord-002808-84np9brx	254	38	how	how	WRB
cord-002808-84np9brx	254	39	L2	L2	NNP
cord-002808-84np9brx	254	40	could	could	MD
cord-002808-84np9brx	254	41	span	span	VB
cord-002808-84np9brx	254	42	the	the	DT
cord-002808-84np9brx	254	43	membrane	membrane	NN
cord-002808-84np9brx	254	44	twice	twice	RB
cord-002808-84np9brx	254	45	to	to	TO
cord-002808-84np9brx	254	46	keep	keep	VB
cord-002808-84np9brx	254	47	the	the	DT
cord-002808-84np9brx	254	48	C	C	NNP
cord-002808-84np9brx	254	49	-	-	HYPH
cord-002808-84np9brx	254	50	terminal	terminal	NN
cord-002808-84np9brx	254	51	BirA	BirA	NNP
cord-002808-84np9brx	254	52	fusion	fusion	NN
cord-002808-84np9brx	254	53	lumenal	lumenal	NNP
cord-002808-84np9brx	254	54	.	.	.
cord-002808-84np9brx	255	1	Membrane	membrane	NN
cord-002808-84np9brx	255	2	-	-	HYPH
cord-002808-84np9brx	255	3	spanning	span	VBG
cord-002808-84np9brx	255	4	bacterial	bacterial	JJ
cord-002808-84np9brx	255	5	toxins	toxin	NNS
cord-002808-84np9brx	255	6	,	,	,
cord-002808-84np9brx	255	7	including	include	VBG
cord-002808-84np9brx	255	8	anthrax	anthrax	NN
cord-002808-84np9brx	255	9	toxin	toxin	NN
cord-002808-84np9brx	255	10	,	,	,
cord-002808-84np9brx	255	11	Diphtheria	Diphtheria	NNP
cord-002808-84np9brx	255	12	toxin	toxin	NN
cord-002808-84np9brx	255	13	,	,	,
cord-002808-84np9brx	255	14	botulinum	botulinum	NN
cord-002808-84np9brx	255	15	toxin	toxin	NN
cord-002808-84np9brx	255	16	,	,	,
cord-002808-84np9brx	255	17	tetanus	tetanus	NN
cord-002808-84np9brx	255	18	toxin	toxin	NN
cord-002808-84np9brx	255	19	,	,	,
cord-002808-84np9brx	255	20	and	and	CC
cord-002808-84np9brx	255	21	Clostridium	clostridium	NN
cord-002808-84np9brx	255	22	difficile	difficile	NN
cord-002808-84np9brx	255	23	toxins	toxin	NNS
cord-002808-84np9brx	255	24	,	,	,
cord-002808-84np9brx	255	25	form	form	NN
cord-002808-84np9brx	255	26	pores	pore	NNS
cord-002808-84np9brx	255	27	through	through	IN
cord-002808-84np9brx	255	28	which	which	WDT
cord-002808-84np9brx	255	29	they	-PRON-	PRP
cord-002808-84np9brx	255	30	can	can	MD
cord-002808-84np9brx	255	31	extrude	extrude	VB
cord-002808-84np9brx	255	32	themselves	-PRON-	PRP
cord-002808-84np9brx	255	33	into	into	IN
cord-002808-84np9brx	255	34	the	the	DT
cord-002808-84np9brx	255	35	cytosol	cytosol	NN
cord-002808-84np9brx	255	36	by	by	IN
cord-002808-84np9brx	255	37	a	a	DT
cord-002808-84np9brx	255	38	variety	variety	NN
cord-002808-84np9brx	255	39	of	of	IN
cord-002808-84np9brx	255	40	protein	protein	NN
cord-002808-84np9brx	255	41	translocation	translocation	NN
cord-002808-84np9brx	255	42	mechanisms	mechanism	NNS
cord-002808-84np9brx	255	43	[	[	-LRB-
cord-002808-84np9brx	255	44	106	106	CD
cord-002808-84np9brx	255	45	,	,	,
cord-002808-84np9brx	255	46	107	107	CD
cord-002808-84np9brx	255	47	]	]	-RRB-
cord-002808-84np9brx	255	48	.	.	.
cord-002808-84np9brx	256	1	Oligomerization	Oligomerization	NNP
cord-002808-84np9brx	256	2	of	of	IN
cord-002808-84np9brx	256	3	individual	individual	JJ
cord-002808-84np9brx	256	4	L2	l2	NN
cord-002808-84np9brx	256	5	molecules	molecule	NNS
cord-002808-84np9brx	256	6	,	,	,
cord-002808-84np9brx	256	7	each	each	DT
cord-002808-84np9brx	256	8	with	with	IN
cord-002808-84np9brx	256	9	a	a	DT
cord-002808-84np9brx	256	10	single	single	JJ
cord-002808-84np9brx	256	11	membrane	membrane	NN
cord-002808-84np9brx	256	12	-	-	HYPH
cord-002808-84np9brx	256	13	spanning	span	VBG
cord-002808-84np9brx	256	14	TMD	TMD	NNP
cord-002808-84np9brx	256	15	,	,	,
cord-002808-84np9brx	256	16	could	could	MD
cord-002808-84np9brx	256	17	theoretically	theoretically	RB
cord-002808-84np9brx	256	18	enable	enable	VB
cord-002808-84np9brx	256	19	a	a	DT
cord-002808-84np9brx	256	20	double	double	JJ
cord-002808-84np9brx	256	21	-	-	HYPH
cord-002808-84np9brx	256	22	pass	pass	NN
cord-002808-84np9brx	256	23	topology	topology	NN
cord-002808-84np9brx	256	24	by	by	IN
cord-002808-84np9brx	256	25	extrusion	extrusion	NN
cord-002808-84np9brx	256	26	of	of	IN
cord-002808-84np9brx	256	27	the	the	DT
cord-002808-84np9brx	256	28	L2	L2	NNP
cord-002808-84np9brx	256	29	C	C	NNP
cord-002808-84np9brx	256	30	-	-	HYPH
cord-002808-84np9brx	256	31	termini	termini	NNP
cord-002808-84np9brx	256	32	back	back	RB
cord-002808-84np9brx	256	33	into	into	IN
cord-002808-84np9brx	256	34	the	the	DT
cord-002808-84np9brx	256	35	lumen	lumen	NN
cord-002808-84np9brx	256	36	through	through	IN
cord-002808-84np9brx	256	37	such	such	PDT
cord-002808-84np9brx	256	38	a	a	DT
cord-002808-84np9brx	256	39	pore	pore	NN
cord-002808-84np9brx	256	40	.	.	.
cord-002808-84np9brx	257	1	This	this	DT
cord-002808-84np9brx	257	2	hypothetical	hypothetical	JJ
cord-002808-84np9brx	257	3	configuration	configuration	NN
cord-002808-84np9brx	257	4	would	would	MD
cord-002808-84np9brx	257	5	place	place	VB
cord-002808-84np9brx	257	6	a	a	DT
cord-002808-84np9brx	257	7	central	central	JJ
cord-002808-84np9brx	257	8	portion	portion	NN
cord-002808-84np9brx	257	9	of	of	IN
cord-002808-84np9brx	257	10	L2	l2	NN
cord-002808-84np9brx	257	11	within	within	IN
cord-002808-84np9brx	257	12	the	the	DT
cord-002808-84np9brx	257	13	cytosol	cytosol	NN
cord-002808-84np9brx	257	14	to	to	TO
cord-002808-84np9brx	257	15	recruit	recruit	VB
cord-002808-84np9brx	257	16	sorting	sorting	NN
cord-002808-84np9brx	257	17	factors	factor	NNS
cord-002808-84np9brx	257	18	and	and	CC
cord-002808-84np9brx	257	19	direct	direct	JJ
cord-002808-84np9brx	257	20	traffic	traffic	NN
cord-002808-84np9brx	257	21	of	of	IN
cord-002808-84np9brx	257	22	the	the	DT
cord-002808-84np9brx	257	23	associated	associate	VBN
cord-002808-84np9brx	257	24	vDNA	vDNA	.
cord-002808-84np9brx	258	1	(	(	-LRB-
cord-002808-84np9brx	258	2	Figure	figure	NN
cord-002808-84np9brx	258	3	4	4	CD
cord-002808-84np9brx	258	4	)	)	-RRB-
cord-002808-84np9brx	258	5	.	.	.
cord-002808-84np9brx	259	1	It	-PRON-	PRP
cord-002808-84np9brx	259	2	should	should	MD
cord-002808-84np9brx	259	3	also	also	RB
cord-002808-84np9brx	259	4	be	be	VB
cord-002808-84np9brx	259	5	noted	note	VBN
cord-002808-84np9brx	259	6	that	that	IN
cord-002808-84np9brx	259	7	such	such	PDT
cord-002808-84np9brx	259	8	a	a	DT
cord-002808-84np9brx	259	9	double	double	JJ
cord-002808-84np9brx	259	10	-	-	HYPH
cord-002808-84np9brx	259	11	pass	pass	NN
cord-002808-84np9brx	259	12	topology	topology	NN
cord-002808-84np9brx	259	13	would	would	MD
cord-002808-84np9brx	259	14	still	still	RB
cord-002808-84np9brx	259	15	be	be	VB
cord-002808-84np9brx	259	16	consistent	consistent	JJ
cord-002808-84np9brx	259	17	with	with	IN
cord-002808-84np9brx	259	18	the	the	DT
cord-002808-84np9brx	259	19	immunofluorescence	immunofluorescence	NN
cord-002808-84np9brx	259	20	data	datum	NNS
cord-002808-84np9brx	259	21	supporting	support	VBG
cord-002808-84np9brx	259	22	a	a	DT
cord-002808-84np9brx	259	23	type	type	NN
cord-002808-84np9brx	259	24	-	-	:
cord-002808-84np9brx	259	25	I	i	NN
cord-002808-84np9brx	259	26	topology	topology	NN
cord-002808-84np9brx	259	27	[	[	-LRB-
cord-002808-84np9brx	259	28	80	80	CD
cord-002808-84np9brx	259	29	]	]	-RRB-
cord-002808-84np9brx	259	30	.	.	.
cord-002808-84np9brx	260	1	Clearly	clearly	RB
cord-002808-84np9brx	260	2	,	,	,
cord-002808-84np9brx	260	3	much	much	RB
cord-002808-84np9brx	260	4	more	more	JJR
cord-002808-84np9brx	260	5	work	work	NN
cord-002808-84np9brx	260	6	is	be	VBZ
cord-002808-84np9brx	260	7	needed	need	VBN
cord-002808-84np9brx	260	8	to	to	TO
cord-002808-84np9brx	260	9	understand	understand	VB
cord-002808-84np9brx	260	10	the	the	DT
cord-002808-84np9brx	260	11	protruding	protrude	VBG
cord-002808-84np9brx	260	12	conformation	conformation	NN
cord-002808-84np9brx	260	13	of	of	IN
cord-002808-84np9brx	260	14	L2	L2	NNP
cord-002808-84np9brx	260	15	during	during	IN
cord-002808-84np9brx	260	16	HPV	HPV	NNP
cord-002808-84np9brx	260	17	infection	infection	NN
cord-002808-84np9brx	260	18	.	.	.
cord-002808-84np9brx	261	1	into	into	IN
cord-002808-84np9brx	261	2	mitosis	mitosis	NN
cord-002808-84np9brx	261	3	[	[	-LRB-
cord-002808-84np9brx	261	4	51	51	CD
cord-002808-84np9brx	261	5	]	]	-RRB-
cord-002808-84np9brx	261	6	.	.	.
cord-002808-84np9brx	262	1	This	this	DT
cord-002808-84np9brx	262	2	data	data	NN
cord-002808-84np9brx	262	3	,	,	,
cord-002808-84np9brx	262	4	however	however	RB
cord-002808-84np9brx	262	5	,	,	,
cord-002808-84np9brx	262	6	is	be	VBZ
cord-002808-84np9brx	262	7	not	not	RB
cord-002808-84np9brx	262	8	in	in	IN
cord-002808-84np9brx	262	9	agreement	agreement	NN
cord-002808-84np9brx	262	10	with	with	IN
cord-002808-84np9brx	262	11	a	a	DT
cord-002808-84np9brx	262	12	strict	strict	JJ
cord-002808-84np9brx	262	13	type	type	NN
cord-002808-84np9brx	262	14	-	-	:
cord-002808-84np9brx	262	15	I	i	NN
cord-002808-84np9brx	262	16	membrane	membrane	NN
cord-002808-84np9brx	262	17	topology	topology	NN
cord-002808-84np9brx	262	18	for	for	IN
cord-002808-84np9brx	262	19	L2	L2	NNP
cord-002808-84np9brx	262	20	.	.	.
cord-002808-84np9brx	263	1	The	the	DT
cord-002808-84np9brx	263	2	lack	lack	NN
cord-002808-84np9brx	263	3	of	of	IN
cord-002808-84np9brx	263	4	translocation	translocation	NN
cord-002808-84np9brx	263	5	signal	signal	NN
cord-002808-84np9brx	263	6	in	in	IN
cord-002808-84np9brx	263	7	the	the	DT
cord-002808-84np9brx	263	8	presence	presence	NN
cord-002808-84np9brx	263	9	of	of	IN
cord-002808-84np9brx	263	10	aphidicolin	aphidicolin	NNP
cord-002808-84np9brx	263	11	implies	imply	VBZ
cord-002808-84np9brx	263	12	that	that	IN
cord-002808-84np9brx	263	13	the	the	DT
cord-002808-84np9brx	263	14	C	C	NNP
cord-002808-84np9brx	263	15	-	-	HYPH
cord-002808-84np9brx	263	16	terminus	terminus	NN
cord-002808-84np9brx	263	17	of	of	IN
cord-002808-84np9brx	263	18	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	263	19	is	be	VBZ
cord-002808-84np9brx	263	20	not	not	RB
cord-002808-84np9brx	263	21	cytosolic	cytosolic	JJ
cord-002808-84np9brx	263	22	,	,	,
cord-002808-84np9brx	263	23	as	as	IN
cord-002808-84np9brx	263	24	it	-PRON-	PRP
cord-002808-84np9brx	263	25	would	would	MD
cord-002808-84np9brx	263	26	be	be	VB
cord-002808-84np9brx	263	27	in	in	IN
cord-002808-84np9brx	263	28	a	a	DT
cord-002808-84np9brx	263	29	type	type	NN
cord-002808-84np9brx	263	30	-	-	:
cord-002808-84np9brx	263	31	I	-PRON-	PRP
cord-002808-84np9brx	263	32	topology	topology	NN
cord-002808-84np9brx	263	33	.	.	.
cord-002808-84np9brx	264	1	Rather	rather	RB
cord-002808-84np9brx	264	2	,	,	,
cord-002808-84np9brx	264	3	it	-PRON-	PRP
cord-002808-84np9brx	264	4	suggests	suggest	VBZ
cord-002808-84np9brx	264	5	that	that	IN
cord-002808-84np9brx	264	6	BirA	BirA	NNP
cord-002808-84np9brx	264	7	is	be	VBZ
cord-002808-84np9brx	264	8	either	either	CC
cord-002808-84np9brx	264	9	lumenal	lumenal	JJ
cord-002808-84np9brx	264	10	or	or	CC
cord-002808-84np9brx	264	11	is	be	VBZ
cord-002808-84np9brx	264	12	somehow	somehow	RB
cord-002808-84np9brx	264	13	obstructed	obstruct	VBN
cord-002808-84np9brx	264	14	from	from	IN
cord-002808-84np9brx	264	15	engaging	engage	VBG
cord-002808-84np9brx	264	16	the	the	DT
cord-002808-84np9brx	264	17	GFP	GFP	NNP
cord-002808-84np9brx	264	18	-	-	HYPH
cord-002808-84np9brx	264	19	BAP	BAP	NNP
cord-002808-84np9brx	264	20	substrate	substrate	NN
cord-002808-84np9brx	264	21	when	when	WRB
cord-002808-84np9brx	264	22	L2	L2	NNP
cord-002808-84np9brx	264	23	is	be	VBZ
cord-002808-84np9brx	264	24	protruding	protrude	VBG
cord-002808-84np9brx	264	25	from	from	IN
cord-002808-84np9brx	264	26	endosomal	endosomal	NNP
cord-002808-84np9brx	264	27	and	and	CC
cord-002808-84np9brx	264	28	TGN	TGN	NNP
cord-002808-84np9brx	264	29	compartments	compartment	NNS
cord-002808-84np9brx	264	30	,	,	,
cord-002808-84np9brx	264	31	only	only	RB
cord-002808-84np9brx	264	32	becoming	become	VBG
cord-002808-84np9brx	264	33	accessible	accessible	JJ
cord-002808-84np9brx	264	34	to	to	IN
cord-002808-84np9brx	264	35	the	the	DT
cord-002808-84np9brx	264	36	cytosol	cytosol	NN
cord-002808-84np9brx	264	37	upon	upon	IN
cord-002808-84np9brx	264	38	entry	entry	NN
cord-002808-84np9brx	264	39	into	into	IN
cord-002808-84np9brx	264	40	mitosis	mitosis	NN
cord-002808-84np9brx	264	41	.	.	.
cord-002808-84np9brx	265	1	A	a	DT
cord-002808-84np9brx	265	2	double	double	JJ
cord-002808-84np9brx	265	3	-	-	HYPH
cord-002808-84np9brx	265	4	pass	pass	NN
cord-002808-84np9brx	265	5	topology	topology	NN
cord-002808-84np9brx	265	6	of	of	IN
cord-002808-84np9brx	265	7	protruding	protrude	VBG
cord-002808-84np9brx	265	8	L2-BirA	L2-BirA	NNS
cord-002808-84np9brx	265	9	would	would	MD
cord-002808-84np9brx	265	10	result	result	VB
cord-002808-84np9brx	265	11	in	in	IN
cord-002808-84np9brx	265	12	a	a	DT
cord-002808-84np9brx	265	13	lumenal	lumenal	JJ
cord-002808-84np9brx	265	14	C	c	NN
cord-002808-84np9brx	265	15	-	-	HYPH
cord-002808-84np9brx	265	16	terminal	terminal	NN
cord-002808-84np9brx	265	17	BirA	BirA	NNP
cord-002808-84np9brx	265	18	(	(	-LRB-
cord-002808-84np9brx	265	19	Figure	Figure	NNP
cord-002808-84np9brx	265	20	4	4	CD
cord-002808-84np9brx	265	21	)	)	-RRB-
cord-002808-84np9brx	265	22	.	.	.
cord-002808-84np9brx	266	1	immunofluorescence	immunofluorescence	NN
cord-002808-84np9brx	266	2	and	and	CC
cord-002808-84np9brx	266	3	trypsin	trypsin	JJ
cord-002808-84np9brx	266	4	susceptibility	susceptibility	NN
cord-002808-84np9brx	266	5	data	datum	NNS
cord-002808-84np9brx	266	6	[	[	-LRB-
cord-002808-84np9brx	266	7	80	80	CD
cord-002808-84np9brx	266	8	]	]	-RRB-
cord-002808-84np9brx	266	9	.	.	.
cord-002808-84np9brx	267	1	(	(	-LRB-
cord-002808-84np9brx	267	2	A	a	NN
cord-002808-84np9brx	267	3	)	)	-RRB-
cord-002808-84np9brx	268	1	In	in	IN
cord-002808-84np9brx	268	2	the	the	DT
cord-002808-84np9brx	268	3	type	type	NN
cord-002808-84np9brx	268	4	-	-	:
cord-002808-84np9brx	268	5	I	i	NN
cord-002808-84np9brx	268	6	model	model	NN
cord-002808-84np9brx	268	7	,	,	,
cord-002808-84np9brx	268	8	the	the	DT
cord-002808-84np9brx	268	9	N	n	CD
cord-002808-84np9brx	268	10	-	-	HYPH
cord-002808-84np9brx	268	11	terminus	terminus	NN
cord-002808-84np9brx	268	12	remains	remain	VBZ
cord-002808-84np9brx	268	13	lumenal	lumenal	JJ
cord-002808-84np9brx	268	14	with	with	IN
cord-002808-84np9brx	268	15	all	all	DT
cord-002808-84np9brx	268	16	~400	~400	NN
cord-002808-84np9brx	268	17	residues	residue	NNS
cord-002808-84np9brx	268	18	downstream	downstream	RB
cord-002808-84np9brx	268	19	of	of	IN
cord-002808-84np9brx	268	20	the	the	DT
cord-002808-84np9brx	268	21	TMD	TMD	NNP
cord-002808-84np9brx	268	22	being	be	VBG
cord-002808-84np9brx	268	23	cytosolic	cytosolic	JJ
cord-002808-84np9brx	268	24	to	to	TO
cord-002808-84np9brx	268	25	recruit	recruit	VB
cord-002808-84np9brx	268	26	sorting	sorting	NN
cord-002808-84np9brx	268	27	factors	factor	NNS
cord-002808-84np9brx	268	28	.	.	.
cord-002808-84np9brx	269	1	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	269	2	would	would	MD
cord-002808-84np9brx	269	3	be	be	VB
cord-002808-84np9brx	269	4	expected	expect	VBN
cord-002808-84np9brx	269	5	to	to	TO
cord-002808-84np9brx	269	6	biotinylate	biotinylate	VB
cord-002808-84np9brx	269	7	substrate	substrate	NN
cord-002808-84np9brx	269	8	in	in	IN
cord-002808-84np9brx	269	9	this	this	DT
cord-002808-84np9brx	269	10	model	model	NN
cord-002808-84np9brx	269	11	,	,	,
cord-002808-84np9brx	269	12	contradicting	contradict	VBG
cord-002808-84np9brx	269	13	the	the	DT
cord-002808-84np9brx	269	14	actual	actual	JJ
cord-002808-84np9brx	269	15	data	datum	NNS
cord-002808-84np9brx	269	16	[	[	-LRB-
cord-002808-84np9brx	269	17	51	51	CD
cord-002808-84np9brx	269	18	]	]	-RRB-
cord-002808-84np9brx	269	19	.	.	.
cord-002808-84np9brx	270	1	(	(	-LRB-
cord-002808-84np9brx	270	2	B	b	NN
cord-002808-84np9brx	270	3	)	)	-RRB-
cord-002808-84np9brx	271	1	In	in	IN
cord-002808-84np9brx	271	2	the	the	DT
cord-002808-84np9brx	271	3	double	double	JJ
cord-002808-84np9brx	271	4	-	-	HYPH
cord-002808-84np9brx	271	5	pass	pass	NN
cord-002808-84np9brx	271	6	model	model	NN
cord-002808-84np9brx	271	7	,	,	,
cord-002808-84np9brx	271	8	both	both	CC
cord-002808-84np9brx	271	9	the	the	DT
cord-002808-84np9brx	271	10	N	N	NNP
cord-002808-84np9brx	271	11	-	-	HYPH
cord-002808-84np9brx	271	12	and	and	CC
cord-002808-84np9brx	271	13	C	C	NNP
cord-002808-84np9brx	271	14	-	-	HYPH
cord-002808-84np9brx	271	15	termini	termini	NNP
cord-002808-84np9brx	271	16	would	would	MD
cord-002808-84np9brx	271	17	be	be	VB
cord-002808-84np9brx	271	18	lumenal	lumenal	JJ
cord-002808-84np9brx	271	19	,	,	,
cord-002808-84np9brx	271	20	with	with	IN
cord-002808-84np9brx	271	21	the	the	DT
cord-002808-84np9brx	271	22	bulk	bulk	NN
cord-002808-84np9brx	271	23	of	of	IN
cord-002808-84np9brx	271	24	L2	L2	NNP
cord-002808-84np9brx	271	25	being	be	VBG
cord-002808-84np9brx	271	26	cytosolic	cytosolic	JJ
cord-002808-84np9brx	271	27	.	.	.
cord-002808-84np9brx	272	1	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	272	2	would	would	MD
cord-002808-84np9brx	272	3	not	not	RB
cord-002808-84np9brx	272	4	be	be	VB
cord-002808-84np9brx	272	5	expected	expect	VBN
cord-002808-84np9brx	272	6	to	to	TO
cord-002808-84np9brx	272	7	biotinylate	biotinylate	VB
cord-002808-84np9brx	272	8	substrate	substrate	NN
cord-002808-84np9brx	272	9	as	as	IN
cord-002808-84np9brx	272	10	observed	observe	VBN
cord-002808-84np9brx	272	11	.	.	.
cord-002808-84np9brx	273	1	However	however	RB
cord-002808-84np9brx	273	2	,	,	,
cord-002808-84np9brx	273	3	the	the	DT
cord-002808-84np9brx	273	4	means	mean	NNS
cord-002808-84np9brx	273	5	by	by	IN
cord-002808-84np9brx	273	6	which	which	WDT
cord-002808-84np9brx	273	7	L2	L2	NNP
cord-002808-84np9brx	273	8	spans	span	VBZ
cord-002808-84np9brx	273	9	the	the	DT
cord-002808-84np9brx	273	10	membrane	membrane	NN
cord-002808-84np9brx	273	11	a	a	DT
cord-002808-84np9brx	273	12	second	second	JJ
cord-002808-84np9brx	273	13	time	time	NN
cord-002808-84np9brx	273	14	is	be	VBZ
cord-002808-84np9brx	273	15	difficult	difficult	JJ
cord-002808-84np9brx	273	16	to	to	TO
cord-002808-84np9brx	273	17	conceptualize	conceptualize	VB
cord-002808-84np9brx	273	18	,	,	,
cord-002808-84np9brx	273	19	as	as	IN
cord-002808-84np9brx	273	20	the	the	DT
cord-002808-84np9brx	273	21	protein	protein	NN
cord-002808-84np9brx	273	22	only	only	RB
cord-002808-84np9brx	273	23	has	have	VBZ
cord-002808-84np9brx	273	24	one	one	CD
cord-002808-84np9brx	273	25	TMD	TMD	NNP
cord-002808-84np9brx	273	26	towards	towards	IN
cord-002808-84np9brx	273	27	the	the	DT
cord-002808-84np9brx	273	28	N	n	CD
cord-002808-84np9brx	273	29	-	-	HYPH
cord-002808-84np9brx	273	30	terminus	terminus	NN
cord-002808-84np9brx	273	31	[	[	-LRB-
cord-002808-84np9brx	273	32	79	79	CD
cord-002808-84np9brx	273	33	]	]	-RRB-
cord-002808-84np9brx	273	34	.	.	.
cord-002808-84np9brx	274	1	In	in	IN
cord-002808-84np9brx	274	2	vitro	vitro	FW
cord-002808-84np9brx	274	3	data	datum	NNS
cord-002808-84np9brx	274	4	suggest	suggest	VBP
cord-002808-84np9brx	274	5	both	both	CC
cord-002808-84np9brx	274	6	the	the	DT
cord-002808-84np9brx	274	7	N	N	NNP
cord-002808-84np9brx	274	8	-	-	HYPH
cord-002808-84np9brx	274	9	and	and	CC
cord-002808-84np9brx	274	10	C	C	NNP
cord-002808-84np9brx	274	11	-	-	HYPH
cord-002808-84np9brx	274	12	termini	termini	NNP
cord-002808-84np9brx	274	13	are	be	VBP
cord-002808-84np9brx	274	14	capable	capable	JJ
cord-002808-84np9brx	274	15	of	of	IN
cord-002808-84np9brx	274	16	non	non	JJ
cord-002808-84np9brx	274	17	-	-	JJ
cord-002808-84np9brx	274	18	speciific	speciific	JJ
cord-002808-84np9brx	274	19	dsDNA	dsdna	RB
cord-002808-84np9brx	274	20	binding	bind	VBG
cord-002808-84np9brx	274	21	through	through	IN
cord-002808-84np9brx	274	22	electrostatic	electrostatic	JJ
cord-002808-84np9brx	274	23	interactions	interaction	NNS
cord-002808-84np9brx	274	24	[	[	-LRB-
cord-002808-84np9brx	274	25	12	12	CD
cord-002808-84np9brx	274	26	,	,	,
cord-002808-84np9brx	274	27	14	14	CD
cord-002808-84np9brx	274	28	]	]	-RRB-
cord-002808-84np9brx	274	29	.	.	.
cord-002808-84np9brx	275	1	immunofluorescence	immunofluorescence	NN
cord-002808-84np9brx	275	2	and	and	CC
cord-002808-84np9brx	275	3	trypsin	trypsin	JJ
cord-002808-84np9brx	275	4	susceptibility	susceptibility	NN
cord-002808-84np9brx	275	5	data	datum	NNS
cord-002808-84np9brx	275	6	[	[	-LRB-
cord-002808-84np9brx	275	7	80	80	CD
cord-002808-84np9brx	275	8	]	]	-RRB-
cord-002808-84np9brx	275	9	.	.	.
cord-002808-84np9brx	276	1	(	(	-LRB-
cord-002808-84np9brx	276	2	A	a	NN
cord-002808-84np9brx	276	3	)	)	-RRB-
cord-002808-84np9brx	277	1	In	in	IN
cord-002808-84np9brx	277	2	the	the	DT
cord-002808-84np9brx	277	3	type	type	NN
cord-002808-84np9brx	277	4	-	-	:
cord-002808-84np9brx	277	5	I	i	NN
cord-002808-84np9brx	277	6	model	model	NN
cord-002808-84np9brx	277	7	,	,	,
cord-002808-84np9brx	277	8	the	the	DT
cord-002808-84np9brx	277	9	N	n	CD
cord-002808-84np9brx	277	10	-	-	HYPH
cord-002808-84np9brx	277	11	terminus	terminus	NN
cord-002808-84np9brx	277	12	remains	remain	VBZ
cord-002808-84np9brx	277	13	lumenal	lumenal	JJ
cord-002808-84np9brx	277	14	with	with	IN
cord-002808-84np9brx	277	15	all~400	all~400	NN
cord-002808-84np9brx	277	16	residues	residue	NNS
cord-002808-84np9brx	277	17	downstream	downstream	RB
cord-002808-84np9brx	277	18	of	of	IN
cord-002808-84np9brx	277	19	the	the	DT
cord-002808-84np9brx	277	20	TMD	TMD	NNP
cord-002808-84np9brx	277	21	being	be	VBG
cord-002808-84np9brx	277	22	cytosolic	cytosolic	JJ
cord-002808-84np9brx	277	23	to	to	TO
cord-002808-84np9brx	277	24	recruit	recruit	VB
cord-002808-84np9brx	277	25	sorting	sorting	NN
cord-002808-84np9brx	277	26	factors	factor	NNS
cord-002808-84np9brx	277	27	.	.	.
cord-002808-84np9brx	278	1	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	278	2	would	would	MD
cord-002808-84np9brx	278	3	be	be	VB
cord-002808-84np9brx	278	4	expected	expect	VBN
cord-002808-84np9brx	278	5	to	to	TO
cord-002808-84np9brx	278	6	biotinylate	biotinylate	VB
cord-002808-84np9brx	278	7	substrate	substrate	NN
cord-002808-84np9brx	278	8	in	in	IN
cord-002808-84np9brx	278	9	this	this	DT
cord-002808-84np9brx	278	10	model	model	NN
cord-002808-84np9brx	278	11	,	,	,
cord-002808-84np9brx	278	12	contradicting	contradict	VBG
cord-002808-84np9brx	278	13	the	the	DT
cord-002808-84np9brx	278	14	actual	actual	JJ
cord-002808-84np9brx	278	15	data	datum	NNS
cord-002808-84np9brx	278	16	[	[	-LRB-
cord-002808-84np9brx	278	17	51	51	CD
cord-002808-84np9brx	278	18	]	]	-RRB-
cord-002808-84np9brx	278	19	.	.	.
cord-002808-84np9brx	279	1	(	(	-LRB-
cord-002808-84np9brx	279	2	B	b	NN
cord-002808-84np9brx	279	3	)	)	-RRB-
cord-002808-84np9brx	280	1	In	in	IN
cord-002808-84np9brx	280	2	the	the	DT
cord-002808-84np9brx	280	3	double	double	JJ
cord-002808-84np9brx	280	4	-	-	HYPH
cord-002808-84np9brx	280	5	pass	pass	NN
cord-002808-84np9brx	280	6	model	model	NN
cord-002808-84np9brx	280	7	,	,	,
cord-002808-84np9brx	280	8	both	both	CC
cord-002808-84np9brx	280	9	the	the	DT
cord-002808-84np9brx	280	10	N	N	NNP
cord-002808-84np9brx	280	11	-	-	HYPH
cord-002808-84np9brx	280	12	and	and	CC
cord-002808-84np9brx	280	13	C	C	NNP
cord-002808-84np9brx	280	14	-	-	HYPH
cord-002808-84np9brx	280	15	termini	termini	NNP
cord-002808-84np9brx	280	16	would	would	MD
cord-002808-84np9brx	280	17	be	be	VB
cord-002808-84np9brx	280	18	lumenal	lumenal	JJ
cord-002808-84np9brx	280	19	,	,	,
cord-002808-84np9brx	280	20	with	with	IN
cord-002808-84np9brx	280	21	the	the	DT
cord-002808-84np9brx	280	22	bulk	bulk	NN
cord-002808-84np9brx	280	23	of	of	IN
cord-002808-84np9brx	280	24	L2	L2	NNP
cord-002808-84np9brx	280	25	being	be	VBG
cord-002808-84np9brx	280	26	cytosolic	cytosolic	JJ
cord-002808-84np9brx	280	27	.	.	.
cord-002808-84np9brx	281	1	L2-BirA	L2-BirA	NNP
cord-002808-84np9brx	281	2	would	would	MD
cord-002808-84np9brx	281	3	not	not	RB
cord-002808-84np9brx	281	4	be	be	VB
cord-002808-84np9brx	281	5	expected	expect	VBN
cord-002808-84np9brx	281	6	to	to	TO
cord-002808-84np9brx	281	7	biotinylate	biotinylate	VB
cord-002808-84np9brx	281	8	substrate	substrate	NN
cord-002808-84np9brx	281	9	as	as	IN
cord-002808-84np9brx	281	10	observed	observe	VBN
cord-002808-84np9brx	281	11	.	.	.
cord-002808-84np9brx	282	1	However	however	RB
cord-002808-84np9brx	282	2	,	,	,
cord-002808-84np9brx	282	3	the	the	DT
cord-002808-84np9brx	282	4	means	mean	NNS
cord-002808-84np9brx	282	5	by	by	IN
cord-002808-84np9brx	282	6	which	which	WDT
cord-002808-84np9brx	282	7	L2	L2	NNP
cord-002808-84np9brx	282	8	spans	span	VBZ
cord-002808-84np9brx	282	9	the	the	DT
cord-002808-84np9brx	282	10	membrane	membrane	NN
cord-002808-84np9brx	282	11	a	a	DT
cord-002808-84np9brx	282	12	second	second	JJ
cord-002808-84np9brx	282	13	time	time	NN
cord-002808-84np9brx	282	14	is	be	VBZ
cord-002808-84np9brx	282	15	difficult	difficult	JJ
cord-002808-84np9brx	282	16	to	to	TO
cord-002808-84np9brx	282	17	conceptualize	conceptualize	VB
cord-002808-84np9brx	282	18	,	,	,
cord-002808-84np9brx	282	19	as	as	IN
cord-002808-84np9brx	282	20	the	the	DT
cord-002808-84np9brx	282	21	protein	protein	NN
cord-002808-84np9brx	282	22	only	only	RB
cord-002808-84np9brx	282	23	has	have	VBZ
cord-002808-84np9brx	282	24	one	one	CD
cord-002808-84np9brx	282	25	TMD	TMD	NNP
cord-002808-84np9brx	282	26	towards	towards	IN
cord-002808-84np9brx	282	27	the	the	DT
cord-002808-84np9brx	282	28	N	n	CD
cord-002808-84np9brx	282	29	-	-	HYPH
cord-002808-84np9brx	282	30	terminus	terminus	NN
cord-002808-84np9brx	282	31	[	[	-LRB-
cord-002808-84np9brx	282	32	79	79	CD
cord-002808-84np9brx	282	33	]	]	-RRB-
cord-002808-84np9brx	282	34	.	.	.
cord-002808-84np9brx	283	1	In	in	IN
cord-002808-84np9brx	283	2	vitro	vitro	FW
cord-002808-84np9brx	283	3	data	datum	NNS
cord-002808-84np9brx	283	4	suggest	suggest	VBP
cord-002808-84np9brx	283	5	both	both	CC
cord-002808-84np9brx	283	6	the	the	DT
cord-002808-84np9brx	283	7	N	N	NNP
cord-002808-84np9brx	283	8	-	-	HYPH
cord-002808-84np9brx	283	9	and	and	CC
cord-002808-84np9brx	283	10	C	C	NNP
cord-002808-84np9brx	283	11	-	-	HYPH
cord-002808-84np9brx	283	12	termini	termini	NNP
cord-002808-84np9brx	283	13	are	be	VBP
cord-002808-84np9brx	283	14	capable	capable	JJ
cord-002808-84np9brx	283	15	of	of	IN
cord-002808-84np9brx	283	16	non	non	JJ
cord-002808-84np9brx	283	17	-	-	JJ
cord-002808-84np9brx	283	18	speciific	speciific	JJ
cord-002808-84np9brx	283	19	dsDNA	dsdna	RB
cord-002808-84np9brx	283	20	binding	bind	VBG
cord-002808-84np9brx	283	21	through	through	IN
cord-002808-84np9brx	283	22	electrostatic	electrostatic	JJ
cord-002808-84np9brx	283	23	interactions	interaction	NNS
cord-002808-84np9brx	283	24	[	[	-LRB-
cord-002808-84np9brx	283	25	12	12	CD
cord-002808-84np9brx	283	26	,	,	,
cord-002808-84np9brx	283	27	14	14	CD
cord-002808-84np9brx	283	28	]	]	-RRB-
cord-002808-84np9brx	283	29	.	.	.
cord-002808-84np9brx	284	1	Regardless	regardless	RB
cord-002808-84np9brx	284	2	of	of	IN
cord-002808-84np9brx	284	3	the	the	DT
cord-002808-84np9brx	284	4	precise	precise	JJ
cord-002808-84np9brx	284	5	mechanisms	mechanism	NNS
cord-002808-84np9brx	284	6	of	of	IN
cord-002808-84np9brx	284	7	L2	l2	NN
cord-002808-84np9brx	284	8	translocation	translocation	NN
cord-002808-84np9brx	284	9	,	,	,
cord-002808-84np9brx	284	10	the	the	DT
cord-002808-84np9brx	284	11	minor	minor	JJ
cord-002808-84np9brx	284	12	capsid	capsid	NN
cord-002808-84np9brx	284	13	protein	protein	NN
cord-002808-84np9brx	284	14	eventually	eventually	RB
cord-002808-84np9brx	284	15	leaves	leave	VBZ
cord-002808-84np9brx	284	16	vesicular	vesicular	JJ
cord-002808-84np9brx	284	17	compartments	compartment	NNS
cord-002808-84np9brx	284	18	and	and	CC
cord-002808-84np9brx	284	19	is	be	VBZ
cord-002808-84np9brx	284	20	seen	see	VBN
cord-002808-84np9brx	284	21	along	along	IN
cord-002808-84np9brx	284	22	with	with	IN
cord-002808-84np9brx	284	23	vDNA	vdna	RB
cord-002808-84np9brx	284	24	within	within	IN
cord-002808-84np9brx	284	25	interphase	interphase	NN
cord-002808-84np9brx	284	26	nuclei	nucleus	NNS
cord-002808-84np9brx	284	27	of	of	IN
cord-002808-84np9brx	284	28	infected	infected	JJ
cord-002808-84np9brx	284	29	cells	cell	NNS
cord-002808-84np9brx	284	30	,	,	,
cord-002808-84np9brx	284	31	localized	localize	VBN
cord-002808-84np9brx	284	32	to	to	TO
cord-002808-84np9brx	284	33	punctate	punctate	VB
cord-002808-84np9brx	284	34	nuclear	nuclear	JJ
cord-002808-84np9brx	284	35	foci	foci	NN
cord-002808-84np9brx	284	36	called	call	VBN
cord-002808-84np9brx	284	37	promyelocytic	promyelocytic	JJ
cord-002808-84np9brx	284	38	leukemia	leukemia	NN
cord-002808-84np9brx	284	39	(	(	-LRB-
cord-002808-84np9brx	284	40	PML	PML	NNP
cord-002808-84np9brx	284	41	)	)	-RRB-
cord-002808-84np9brx	284	42	nuclear	nuclear	JJ
cord-002808-84np9brx	284	43	domains	domain	NNS
cord-002808-84np9brx	284	44	,	,	,
cord-002808-84np9brx	284	45	also	also	RB
cord-002808-84np9brx	284	46	known	know	VBN
cord-002808-84np9brx	284	47	as	as	IN
cord-002808-84np9brx	284	48	PML	PML	NNP
cord-002808-84np9brx	284	49	oncogenic	oncogenic	JJ
cord-002808-84np9brx	284	50	domains	domain	NNS
cord-002808-84np9brx	284	51	(	(	-LRB-
cord-002808-84np9brx	284	52	PODS	PODS	NNP
cord-002808-84np9brx	284	53	)	)	-RRB-
cord-002808-84np9brx	284	54	,	,	,
cord-002808-84np9brx	284	55	or	or	CC
cord-002808-84np9brx	284	56	ND10	ND10	NNP
cord-002808-84np9brx	284	57	bodies	body	NNS
cord-002808-84np9brx	284	58	[	[	-LRB-
cord-002808-84np9brx	284	59	108	108	CD
cord-002808-84np9brx	284	60	]	]	-RRB-
cord-002808-84np9brx	284	61	.	.	.
cord-002808-84np9brx	285	1	PML	PML	NNP
cord-002808-84np9brx	285	2	bodies	body	NNS
cord-002808-84np9brx	285	3	are	be	VBP
cord-002808-84np9brx	285	4	small	small	JJ
cord-002808-84np9brx	285	5	nuclear	nuclear	JJ
cord-002808-84np9brx	285	6	structures	structure	NNS
cord-002808-84np9brx	285	7	,	,	,
cord-002808-84np9brx	285	8	organized	organize	VBN
cord-002808-84np9brx	285	9	by	by	IN
cord-002808-84np9brx	285	10	the	the	DT
cord-002808-84np9brx	285	11	PML	PML	NNP
cord-002808-84np9brx	285	12	protein	protein	NN
cord-002808-84np9brx	285	13	for	for	IN
cord-002808-84np9brx	285	14	which	which	WDT
cord-002808-84np9brx	285	15	they	-PRON-	PRP
cord-002808-84np9brx	285	16	are	be	VBP
cord-002808-84np9brx	285	17	named	name	VBN
cord-002808-84np9brx	285	18	.	.	.
cord-002808-84np9brx	286	1	These	these	DT
cord-002808-84np9brx	286	2	dynamic	dynamic	JJ
cord-002808-84np9brx	286	3	domains	domain	NNS
cord-002808-84np9brx	286	4	are	be	VBP
cord-002808-84np9brx	286	5	present	present	JJ
cord-002808-84np9brx	286	6	in	in	IN
cord-002808-84np9brx	286	7	most	most	JJS
cord-002808-84np9brx	286	8	cells	cell	NNS
cord-002808-84np9brx	286	9	,	,	,
cord-002808-84np9brx	286	10	and	and	CC
cord-002808-84np9brx	286	11	are	be	VBP
cord-002808-84np9brx	286	12	assembled	assemble	VBN
cord-002808-84np9brx	286	13	and	and	CC
cord-002808-84np9brx	286	14	remodeled	remodel	VBN
cord-002808-84np9brx	286	15	in	in	IN
cord-002808-84np9brx	286	16	response	response	NN
cord-002808-84np9brx	286	17	to	to	IN
cord-002808-84np9brx	286	18	a	a	DT
cord-002808-84np9brx	286	19	variety	variety	NN
cord-002808-84np9brx	286	20	of	of	IN
cord-002808-84np9brx	286	21	cellular	cellular	JJ
cord-002808-84np9brx	286	22	stresses	stress	NNS
cord-002808-84np9brx	286	23	,	,	,
cord-002808-84np9brx	286	24	including	include	VBG
cord-002808-84np9brx	286	25	infection	infection	NN
cord-002808-84np9brx	286	26	,	,	,
cord-002808-84np9brx	287	1	innate	innate	JJ
cord-002808-84np9brx	287	2	immune	immune	JJ
cord-002808-84np9brx	287	3	triggers	trigger	NNS
cord-002808-84np9brx	287	4	/	/	SYM
cord-002808-84np9brx	287	5	interferon	interferon	NN
cord-002808-84np9brx	287	6	(	(	-LRB-
cord-002808-84np9brx	287	7	IFN	IFN	NNP
cord-002808-84np9brx	287	8	)	)	-RRB-
cord-002808-84np9brx	287	9	,	,	,
cord-002808-84np9brx	287	10	heat	heat	NN
cord-002808-84np9brx	287	11	shock	shock	NN
cord-002808-84np9brx	287	12	,	,	,
cord-002808-84np9brx	287	13	DNA	dna	NN
cord-002808-84np9brx	287	14	damage	damage	NN
cord-002808-84np9brx	287	15	pathways	pathway	NNS
cord-002808-84np9brx	287	16	,	,	,
cord-002808-84np9brx	287	17	and	and	CC
cord-002808-84np9brx	287	18	metabolic	metabolic	JJ
cord-002808-84np9brx	287	19	stress	stress	NN
cord-002808-84np9brx	287	20	[	[	-LRB-
cord-002808-84np9brx	287	21	109	109	CD
cord-002808-84np9brx	287	22	]	]	-RRB-
cord-002808-84np9brx	287	23	[	[	-LRB-
cord-002808-84np9brx	287	24	110	110	CD
cord-002808-84np9brx	287	25	]	]	-RRB-
cord-002808-84np9brx	287	26	[	[	-LRB-
cord-002808-84np9brx	287	27	111	111	CD
cord-002808-84np9brx	287	28	]	]	-RRB-
cord-002808-84np9brx	287	29	.	.	.
cord-002808-84np9brx	288	1	PML	PML	NNP
cord-002808-84np9brx	288	2	bodies	body	NNS
cord-002808-84np9brx	288	3	modulate	modulate	VBP
cord-002808-84np9brx	288	4	a	a	DT
cord-002808-84np9brx	288	5	wide	wide	JJ
cord-002808-84np9brx	288	6	variety	variety	NN
cord-002808-84np9brx	288	7	of	of	IN
cord-002808-84np9brx	288	8	cellular	cellular	JJ
cord-002808-84np9brx	288	9	responses	response	NNS
cord-002808-84np9brx	288	10	via	via	IN
cord-002808-84np9brx	288	11	recruitment	recruitment	NN
cord-002808-84np9brx	288	12	,	,	,
cord-002808-84np9brx	288	13	retention	retention	NN
cord-002808-84np9brx	288	14	,	,	,
cord-002808-84np9brx	288	15	and	and	CC
cord-002808-84np9brx	288	16	modification	modification	NN
cord-002808-84np9brx	288	17	of	of	IN
cord-002808-84np9brx	288	18	numerous	numerous	JJ
cord-002808-84np9brx	288	19	proteins	protein	NNS
cord-002808-84np9brx	288	20	including	include	VBG
cord-002808-84np9brx	288	21	the	the	DT
cord-002808-84np9brx	288	22	transcriptional	transcriptional	JJ
cord-002808-84np9brx	288	23	repressor	repressor	NN
cord-002808-84np9brx	288	24	Daxx	Daxx	NNP
cord-002808-84np9brx	288	25	,	,	,
cord-002808-84np9brx	288	26	tumor	tumor	NN
cord-002808-84np9brx	288	27	suppressor	suppressor	NN
cord-002808-84np9brx	288	28	Sp100	Sp100	NNS
cord-002808-84np9brx	288	29	,	,	,
cord-002808-84np9brx	288	30	transcriptional	transcriptional	JJ
cord-002808-84np9brx	288	31	regulator	regulator	NN
cord-002808-84np9brx	288	32	ATRX	ATRX	NNP
cord-002808-84np9brx	288	33	,	,	,
cord-002808-84np9brx	288	34	DNA	dna	NN
cord-002808-84np9brx	288	35	helicase	helicase	NN
cord-002808-84np9brx	288	36	BLM	BLM	NNP
cord-002808-84np9brx	288	37	,	,	,
cord-002808-84np9brx	288	38	kinase	kinase	NN
cord-002808-84np9brx	288	39	HIPK2	hipk2	UH
cord-002808-84np9brx	288	40	,	,	,
cord-002808-84np9brx	288	41	and	and	CC
cord-002808-84np9brx	288	42	a	a	DT
cord-002808-84np9brx	288	43	multitude	multitude	NN
cord-002808-84np9brx	288	44	of	of	IN
cord-002808-84np9brx	288	45	other	other	JJ
cord-002808-84np9brx	288	46	host	host	NN
cord-002808-84np9brx	288	47	proteins	protein	NNS
cord-002808-84np9brx	288	48	.	.	.
cord-002808-84np9brx	289	1	The	the	DT
cord-002808-84np9brx	289	2	PML	PML	NNP
cord-002808-84np9brx	289	3	protein	protein	NN
cord-002808-84np9brx	289	4	,	,	,
cord-002808-84np9brx	289	5	which	which	WDT
cord-002808-84np9brx	289	6	has	have	VBZ
cord-002808-84np9brx	289	7	many	many	JJ
cord-002808-84np9brx	289	8	different	different	JJ
cord-002808-84np9brx	289	9	isoforms	isoform	NNS
cord-002808-84np9brx	289	10	,	,	,
cord-002808-84np9brx	289	11	is	be	VBZ
cord-002808-84np9brx	289	12	critical	critical	JJ
cord-002808-84np9brx	289	13	to	to	IN
cord-002808-84np9brx	289	14	the	the	DT
cord-002808-84np9brx	289	15	assembly	assembly	NN
cord-002808-84np9brx	289	16	of	of	IN
cord-002808-84np9brx	289	17	PML	PML	NNP
cord-002808-84np9brx	289	18	bodies	body	NNS
cord-002808-84np9brx	289	19	and	and	CC
cord-002808-84np9brx	289	20	recruitment	recruitment	NN
cord-002808-84np9brx	289	21	of	of	IN
cord-002808-84np9brx	289	22	host	host	NN
cord-002808-84np9brx	289	23	proteins	protein	NNS
cord-002808-84np9brx	289	24	to	to	IN
cord-002808-84np9brx	289	25	these	these	DT
cord-002808-84np9brx	289	26	foci	focus	NNS
cord-002808-84np9brx	289	27	[	[	-LRB-
cord-002808-84np9brx	289	28	112	112	CD
cord-002808-84np9brx	289	29	]	]	-RRB-
cord-002808-84np9brx	289	30	.	.	.
cord-002808-84np9brx	290	1	Many	many	JJ
cord-002808-84np9brx	290	2	PML	PML	NNP
cord-002808-84np9brx	290	3	-	-	HYPH
cord-002808-84np9brx	290	4	associated	associate	VBN
cord-002808-84np9brx	290	5	proteins	protein	NNS
cord-002808-84np9brx	290	6	are	be	VBP
cord-002808-84np9brx	290	7	either	either	CC
cord-002808-84np9brx	290	8	directly	directly	RB
cord-002808-84np9brx	290	9	conjugated	conjugate	VBN
cord-002808-84np9brx	290	10	to	to	IN
cord-002808-84np9brx	290	11	small	small	JJ
cord-002808-84np9brx	290	12	ubiquitin	ubiquitin	NN
cord-002808-84np9brx	290	13	-	-	HYPH
cord-002808-84np9brx	290	14	like	like	JJ
cord-002808-84np9brx	290	15	modifier	modifier	NN
cord-002808-84np9brx	290	16	(	(	-LRB-
cord-002808-84np9brx	290	17	SUMO	SUMO	NNP
cord-002808-84np9brx	290	18	)	)	-RRB-
cord-002808-84np9brx	290	19	proteins	protein	NNS
cord-002808-84np9brx	290	20	or	or	CC
cord-002808-84np9brx	290	21	contain	contain	VBP
cord-002808-84np9brx	290	22	short	short	JJ
cord-002808-84np9brx	290	23	linear	linear	JJ
cord-002808-84np9brx	290	24	SUMO	sumo	NN
cord-002808-84np9brx	290	25	-	-	HYPH
cord-002808-84np9brx	290	26	interaction	interaction	NN
cord-002808-84np9brx	290	27	motifs	motif	NNS
cord-002808-84np9brx	290	28	(	(	-LRB-
cord-002808-84np9brx	290	29	SIMs	sim	NNS
cord-002808-84np9brx	290	30	)	)	-RRB-
cord-002808-84np9brx	290	31	,	,	,
cord-002808-84np9brx	290	32	or	or	CC
cord-002808-84np9brx	290	33	both	both	DT
cord-002808-84np9brx	290	34	.	.	.
cord-002808-84np9brx	291	1	In	in	IN
cord-002808-84np9brx	291	2	addition	addition	NN
cord-002808-84np9brx	291	3	to	to	IN
cord-002808-84np9brx	291	4	PML	PML	NNP
cord-002808-84np9brx	291	5	oligomerization	oligomerization	NN
cord-002808-84np9brx	291	6	,	,	,
cord-002808-84np9brx	291	7	SUMOylation	sumoylation	NN
cord-002808-84np9brx	291	8	and	and	CC
cord-002808-84np9brx	291	9	SUMO	SUMO	NNP
cord-002808-84np9brx	291	10	-	-	HYPH
cord-002808-84np9brx	291	11	SIM	sim	NN
cord-002808-84np9brx	291	12	networks	network	NNS
cord-002808-84np9brx	291	13	are	be	VBP
cord-002808-84np9brx	291	14	believed	believe	VBN
cord-002808-84np9brx	291	15	to	to	TO
cord-002808-84np9brx	291	16	be	be	VB
cord-002808-84np9brx	291	17	important	important	JJ
cord-002808-84np9brx	291	18	to	to	IN
cord-002808-84np9brx	291	19	PML	PML	NNP
cord-002808-84np9brx	291	20	assembly	assembly	NN
cord-002808-84np9brx	291	21	and	and	CC
cord-002808-84np9brx	291	22	dynamics	dynamic	NNS
cord-002808-84np9brx	291	23	[	[	-LRB-
cord-002808-84np9brx	291	24	113	113	CD
cord-002808-84np9brx	291	25	]	]	-RRB-
cord-002808-84np9brx	291	26	.	.	.
cord-002808-84np9brx	292	1	Given	give	VBN
cord-002808-84np9brx	292	2	the	the	DT
cord-002808-84np9brx	292	3	role	role	NN
cord-002808-84np9brx	292	4	of	of	IN
cord-002808-84np9brx	292	5	PML	PML	NNP
cord-002808-84np9brx	292	6	bodies	body	NNS
cord-002808-84np9brx	292	7	in	in	IN
cord-002808-84np9brx	292	8	innate	innate	JJ
cord-002808-84np9brx	292	9	antiviral	antiviral	JJ
cord-002808-84np9brx	292	10	responses	response	NNS
cord-002808-84np9brx	292	11	,	,	,
cord-002808-84np9brx	292	12	many	many	JJ
cord-002808-84np9brx	292	13	viruses	virus	NNS
cord-002808-84np9brx	292	14	have	have	VBP
cord-002808-84np9brx	292	15	been	be	VBN
cord-002808-84np9brx	292	16	shown	show	VBN
cord-002808-84np9brx	292	17	to	to	TO
cord-002808-84np9brx	292	18	target	target	VB
cord-002808-84np9brx	292	19	PML	PML	NNP
cord-002808-84np9brx	292	20	bodies	body	NNS
cord-002808-84np9brx	292	21	or	or	CC
cord-002808-84np9brx	292	22	induce	induce	VB
cord-002808-84np9brx	292	23	degradation	degradation	NN
cord-002808-84np9brx	292	24	or	or	CC
cord-002808-84np9brx	292	25	remodeling	remodeling	NN
cord-002808-84np9brx	292	26	of	of	IN
cord-002808-84np9brx	292	27	specific	specific	JJ
cord-002808-84np9brx	292	28	PML	PML	NNP
cord-002808-84np9brx	292	29	components	component	NNS
cord-002808-84np9brx	292	30	[	[	-LRB-
cord-002808-84np9brx	292	31	114	114	CD
cord-002808-84np9brx	292	32	,	,	,
cord-002808-84np9brx	292	33	115	115	CD
cord-002808-84np9brx	292	34	]	]	-RRB-
cord-002808-84np9brx	292	35	.	.	.
cord-002808-84np9brx	293	1	PML	PML	NNP
cord-002808-84np9brx	293	2	bodies	body	NNS
cord-002808-84np9brx	293	3	have	have	VBP
cord-002808-84np9brx	293	4	been	be	VBN
cord-002808-84np9brx	293	5	shown	show	VBN
cord-002808-84np9brx	293	6	to	to	TO
cord-002808-84np9brx	293	7	be	be	VB
cord-002808-84np9brx	293	8	important	important	JJ
cord-002808-84np9brx	293	9	for	for	IN
cord-002808-84np9brx	293	10	efficient	efficient	JJ
cord-002808-84np9brx	293	11	infection	infection	NN
cord-002808-84np9brx	293	12	from	from	IN
cord-002808-84np9brx	293	13	reporter	reporter	NN
cord-002808-84np9brx	293	14	-	-	HYPH
cord-002808-84np9brx	293	15	expressing	express	VBG
cord-002808-84np9brx	293	16	HPV16	hpv16	NN
cord-002808-84np9brx	293	17	pseudoviruses	pseudoviruse	NNS
cord-002808-84np9brx	293	18	,	,	,
cord-002808-84np9brx	293	19	as	as	RB
cord-002808-84np9brx	293	20	well	well	RB
cord-002808-84np9brx	293	21	as	as	IN
cord-002808-84np9brx	293	22	authentic	authentic	JJ
cord-002808-84np9brx	293	23	BPV	BPV	NNP
cord-002808-84np9brx	293	24	virions	virion	NNS
cord-002808-84np9brx	293	25	[	[	-LRB-
cord-002808-84np9brx	293	26	108	108	CD
cord-002808-84np9brx	293	27	]	]	-RRB-
cord-002808-84np9brx	293	28	,	,	,
cord-002808-84np9brx	293	29	suggesting	suggest	VBG
cord-002808-84np9brx	293	30	that	that	IN
cord-002808-84np9brx	293	31	the	the	DT
cord-002808-84np9brx	293	32	vDNA	vdna	NN
cord-002808-84np9brx	293	33	is	be	VBZ
cord-002808-84np9brx	293	34	actively	actively	RB
cord-002808-84np9brx	293	35	targeted	target	VBN
cord-002808-84np9brx	293	36	to	to	IN
cord-002808-84np9brx	293	37	these	these	DT
cord-002808-84np9brx	293	38	sites	site	NNS
cord-002808-84np9brx	293	39	by	by	IN
cord-002808-84np9brx	293	40	L2	L2	NNP
cord-002808-84np9brx	293	41	upon	upon	IN
cord-002808-84np9brx	293	42	infection	infection	NN
cord-002808-84np9brx	293	43	.	.	.
cord-002808-84np9brx	294	1	Ectopically	Ectopically	NNP
cord-002808-84np9brx	294	2	expressed	express	VBD
cord-002808-84np9brx	294	3	L2	L2	NNP
cord-002808-84np9brx	294	4	can	can	MD
cord-002808-84np9brx	294	5	localize	localize	VB
cord-002808-84np9brx	294	6	to	to	IN
cord-002808-84np9brx	294	7	PML	PML	NNP
cord-002808-84np9brx	294	8	bodies	body	NNS
cord-002808-84np9brx	294	9	,	,	,
cord-002808-84np9brx	294	10	remodeling	remodel	VBG
cord-002808-84np9brx	294	11	them	-PRON-	PRP
cord-002808-84np9brx	294	12	through	through	IN
cord-002808-84np9brx	294	13	recruitment	recruitment	NN
cord-002808-84np9brx	294	14	of	of	IN
cord-002808-84np9brx	294	15	Daxx	Daxx	NNP
cord-002808-84np9brx	294	16	and	and	CC
cord-002808-84np9brx	294	17	depletion	depletion	NN
cord-002808-84np9brx	294	18	of	of	IN
cord-002808-84np9brx	294	19	Sp100	Sp100	NNS
cord-002808-84np9brx	294	20	[	[	-LRB-
cord-002808-84np9brx	294	21	116	116	CD
cord-002808-84np9brx	294	22	]	]	-RRB-
cord-002808-84np9brx	294	23	.	.	.
cord-002808-84np9brx	295	1	In	in	IN
cord-002808-84np9brx	295	2	older	old	JJR
cord-002808-84np9brx	295	3	studies	study	NNS
cord-002808-84np9brx	295	4	,	,	,
cord-002808-84np9brx	295	5	the	the	DT
cord-002808-84np9brx	295	6	ability	ability	NN
cord-002808-84np9brx	295	7	of	of	IN
cord-002808-84np9brx	295	8	GFP	GFP	NNP
cord-002808-84np9brx	295	9	-	-	HYPH
cord-002808-84np9brx	295	10	L2	L2	NNP
cord-002808-84np9brx	295	11	fusions	fusion	NNS
cord-002808-84np9brx	295	12	to	to	TO
cord-002808-84np9brx	295	13	localize	localize	VB
cord-002808-84np9brx	295	14	and	and	CC
cord-002808-84np9brx	295	15	induce	induce	VB
cord-002808-84np9brx	295	16	remodeling	remodeling	NN
cord-002808-84np9brx	295	17	of	of	IN
cord-002808-84np9brx	295	18	PML	PML	NNP
cord-002808-84np9brx	295	19	bodies	body	NNS
cord-002808-84np9brx	295	20	was	be	VBD
cord-002808-84np9brx	295	21	mapped	map	VBN
cord-002808-84np9brx	295	22	to	to	IN
cord-002808-84np9brx	295	23	a	a	DT
cord-002808-84np9brx	295	24	C	c	NN
cord-002808-84np9brx	295	25	-	-	HYPH
cord-002808-84np9brx	295	26	terminal	terminal	NN
cord-002808-84np9brx	295	27	region	region	NN
cord-002808-84np9brx	295	28	of	of	IN
cord-002808-84np9brx	295	29	L2	L2	NNP
cord-002808-84np9brx	295	30	(	(	-LRB-
cord-002808-84np9brx	295	31	residues	residue	NNS
cord-002808-84np9brx	295	32	360	360	CD
cord-002808-84np9brx	295	33	-	-	HYPH
cord-002808-84np9brx	295	34	420	420	CD
cord-002808-84np9brx	295	35	for	for	IN
cord-002808-84np9brx	295	36	HPV33	HPV33	NNP
cord-002808-84np9brx	295	37	)	)	-RRB-
cord-002808-84np9brx	295	38	[	[	-LRB-
cord-002808-84np9brx	295	39	117	117	CD
cord-002808-84np9brx	295	40	]	]	-RRB-
cord-002808-84np9brx	295	41	.	.	.
cord-002808-84np9brx	296	1	L2	L2	NNP
cord-002808-84np9brx	296	2	can	can	MD
cord-002808-84np9brx	296	3	itself	-PRON-	PRP
cord-002808-84np9brx	296	4	be	be	VB
cord-002808-84np9brx	296	5	SUMOylated	sumoylate	VBN
cord-002808-84np9brx	296	6	at	at	IN
cord-002808-84np9brx	296	7	a	a	DT
cord-002808-84np9brx	296	8	conserved	conserved	JJ
cord-002808-84np9brx	296	9	lysine	lysine	NN
cord-002808-84np9brx	296	10	residue	residue	NN
cord-002808-84np9brx	296	11	(	(	-LRB-
cord-002808-84np9brx	296	12	K35	K35	NNP
cord-002808-84np9brx	296	13	for	for	IN
cord-002808-84np9brx	296	14	HPV16	hpv16	ADD
cord-002808-84np9brx	296	15	)	)	-RRB-
cord-002808-84np9brx	296	16	when	when	WRB
cord-002808-84np9brx	296	17	ectopically	ectopically	RB
cord-002808-84np9brx	296	18	expressed	express	VBN
cord-002808-84np9brx	296	19	,	,	,
cord-002808-84np9brx	296	20	but	but	CC
cord-002808-84np9brx	296	21	recent	recent	JJ
cord-002808-84np9brx	296	22	work	work	NN
cord-002808-84np9brx	296	23	suggests	suggest	VBZ
cord-002808-84np9brx	296	24	this	this	DT
cord-002808-84np9brx	296	25	modification	modification	NN
cord-002808-84np9brx	296	26	is	be	VBZ
cord-002808-84np9brx	296	27	not	not	RB
cord-002808-84np9brx	296	28	important	important	JJ
cord-002808-84np9brx	296	29	for	for	IN
cord-002808-84np9brx	296	30	PML	PML	NNP
cord-002808-84np9brx	296	31	body	body	NN
cord-002808-84np9brx	296	32	localization	localization	NN
cord-002808-84np9brx	296	33	[	[	-LRB-
cord-002808-84np9brx	296	34	118	118	CD
cord-002808-84np9brx	296	35	,	,	,
cord-002808-84np9brx	296	36	119	119	CD
cord-002808-84np9brx	296	37	]	]	-RRB-
cord-002808-84np9brx	296	38	.	.	.
cord-002808-84np9brx	297	1	Rather	rather	RB
cord-002808-84np9brx	297	2	,	,	,
cord-002808-84np9brx	297	3	a	a	DT
cord-002808-84np9brx	297	4	moderately	moderately	RB
cord-002808-84np9brx	297	5	conserved	conserve	VBN
cord-002808-84np9brx	297	6	SIM	sim	NN
cord-002808-84np9brx	297	7	(	(	-LRB-
cord-002808-84np9brx	297	8	DIVAL	DIVAL	NNP
cord-002808-84np9brx	297	9	,	,	,
cord-002808-84np9brx	297	10	residues	residue	VBZ
cord-002808-84np9brx	297	11	285	285	CD
cord-002808-84np9brx	297	12	-	-	HYPH
cord-002808-84np9brx	297	13	289	289	CD
cord-002808-84np9brx	297	14	for	for	IN
cord-002808-84np9brx	297	15	HPV16	hpv16	ADD
cord-002808-84np9brx	297	16	,	,	,
cord-002808-84np9brx	297	17	see	see	VB
cord-002808-84np9brx	297	18	Figure	figure	NN
cord-002808-84np9brx	297	19	1	1	CD
cord-002808-84np9brx	297	20	)	)	-RRB-
cord-002808-84np9brx	297	21	has	have	VBZ
cord-002808-84np9brx	297	22	been	be	VBN
cord-002808-84np9brx	297	23	implicated	implicate	VBN
cord-002808-84np9brx	297	24	in	in	IN
cord-002808-84np9brx	297	25	PML	PML	NNP
cord-002808-84np9brx	297	26	localization	localization	NN
cord-002808-84np9brx	297	27	of	of	IN
cord-002808-84np9brx	297	28	ectopically	ectopically	RB
cord-002808-84np9brx	297	29	expressed	express	VBN
cord-002808-84np9brx	297	30	untagged	untagged	JJ
cord-002808-84np9brx	297	31	full	full	JJ
cord-002808-84np9brx	297	32	length	length	NN
cord-002808-84np9brx	297	33	,	,	,
cord-002808-84np9brx	297	34	L2	L2	NNP
cord-002808-84np9brx	297	35	[	[	-LRB-
cord-002808-84np9brx	297	36	118	118	CD
cord-002808-84np9brx	297	37	]	]	-RRB-
cord-002808-84np9brx	297	38	.	.	.
cord-002808-84np9brx	298	1	Precise	precise	JJ
cord-002808-84np9brx	298	2	mechanisms	mechanism	NNS
cord-002808-84np9brx	298	3	of	of	IN
cord-002808-84np9brx	298	4	L2-dependent	L2-dependent	NNP
cord-002808-84np9brx	298	5	PML	PML	NNP
cord-002808-84np9brx	298	6	body	body	NN
cord-002808-84np9brx	298	7	remodeling	remodeling	NN
cord-002808-84np9brx	298	8	have	have	VBP
cord-002808-84np9brx	298	9	yet	yet	RB
cord-002808-84np9brx	298	10	to	to	TO
cord-002808-84np9brx	298	11	be	be	VB
cord-002808-84np9brx	298	12	worked	work	VBN
cord-002808-84np9brx	298	13	out	out	RP
cord-002808-84np9brx	298	14	but	but	CC
cord-002808-84np9brx	298	15	ectopic	ectopic	JJ
cord-002808-84np9brx	298	16	overexpression	overexpression	NN
cord-002808-84np9brx	298	17	studies	study	NNS
cord-002808-84np9brx	298	18	must	must	MD
cord-002808-84np9brx	298	19	be	be	VB
cord-002808-84np9brx	298	20	interpreted	interpret	VBN
cord-002808-84np9brx	298	21	with	with	IN
cord-002808-84np9brx	298	22	caution	caution	NN
cord-002808-84np9brx	298	23	since	since	IN
cord-002808-84np9brx	298	24	the	the	DT
cord-002808-84np9brx	298	25	mode	mode	NN
cord-002808-84np9brx	298	26	of	of	IN
cord-002808-84np9brx	298	27	L2	L2	NNP
cord-002808-84np9brx	298	28	gene	gene	NN
cord-002808-84np9brx	298	29	transfection	transfection	NN
cord-002808-84np9brx	298	30	/	/	SYM
cord-002808-84np9brx	298	31	delivery	delivery	NN
cord-002808-84np9brx	298	32	has	have	VBZ
cord-002808-84np9brx	298	33	been	be	VBN
cord-002808-84np9brx	298	34	shown	show	VBN
cord-002808-84np9brx	298	35	to	to	IN
cord-002808-84np9brx	298	36	heavily	heavily	RB
cord-002808-84np9brx	298	37	influence	influence	VB
cord-002808-84np9brx	298	38	nuclear	nuclear	JJ
cord-002808-84np9brx	298	39	/	/	SYM
cord-002808-84np9brx	298	40	PML	PML	NNP
cord-002808-84np9brx	298	41	localization	localization	NN
cord-002808-84np9brx	298	42	of	of	IN
cord-002808-84np9brx	298	43	L2	l2	NN
cord-002808-84np9brx	298	44	[	[	-LRB-
cord-002808-84np9brx	298	45	120	120	CD
cord-002808-84np9brx	298	46	]	]	-RRB-
cord-002808-84np9brx	298	47	.	.	.
cord-002808-84np9brx	299	1	Recent	recent	JJ
cord-002808-84np9brx	299	2	work	work	NN
cord-002808-84np9brx	299	3	suggests	suggest	VBZ
cord-002808-84np9brx	299	4	that	that	IN
cord-002808-84np9brx	299	5	the	the	DT
cord-002808-84np9brx	299	6	PML	PML	NNP
cord-002808-84np9brx	299	7	component	component	NN
cord-002808-84np9brx	299	8	Sp100	Sp100	NNS
cord-002808-84np9brx	299	9	restricts	restrict	VBZ
cord-002808-84np9brx	299	10	HPV	hpv	NN
cord-002808-84np9brx	299	11	transcription	transcription	NN
cord-002808-84np9brx	299	12	and	and	CC
cord-002808-84np9brx	299	13	vDNA	vdna	IN
cord-002808-84np9brx	299	14	replication	replication	NN
cord-002808-84np9brx	299	15	[	[	-LRB-
cord-002808-84np9brx	299	16	121	121	CD
cord-002808-84np9brx	299	17	]	]	-RRB-
cord-002808-84np9brx	299	18	,	,	,
cord-002808-84np9brx	299	19	favoring	favor	VBG
cord-002808-84np9brx	299	20	a	a	DT
cord-002808-84np9brx	299	21	model	model	NN
cord-002808-84np9brx	299	22	whereby	whereby	WRB
cord-002808-84np9brx	299	23	incoming	incoming	JJ
cord-002808-84np9brx	299	24	L2	L2	NNP
cord-002808-84np9brx	299	25	might	may	MD
cord-002808-84np9brx	299	26	promote	promote	VB
cord-002808-84np9brx	299	27	a	a	DT
cord-002808-84np9brx	299	28	nuclear	nuclear	JJ
cord-002808-84np9brx	299	29	environment	environment	NN
cord-002808-84np9brx	299	30	conducive	conducive	JJ
cord-002808-84np9brx	299	31	for	for	IN
cord-002808-84np9brx	299	32	early	early	JJ
cord-002808-84np9brx	299	33	HPV	hpv	NN
cord-002808-84np9brx	299	34	gene	gene	NN
cord-002808-84np9brx	299	35	transcription	transcription	NN
cord-002808-84np9brx	299	36	and	and	CC
cord-002808-84np9brx	299	37	genome	genome	NN
cord-002808-84np9brx	299	38	maintenance	maintenance	NN
cord-002808-84np9brx	299	39	in	in	IN
cord-002808-84np9brx	299	40	basal	basal	NN
cord-002808-84np9brx	299	41	cells	cell	NNS
cord-002808-84np9brx	299	42	.	.	.
cord-002808-84np9brx	300	1	During	during	IN
cord-002808-84np9brx	300	2	cell	cell	NN
cord-002808-84np9brx	300	3	division	division	NN
cord-002808-84np9brx	300	4	,	,	,
cord-002808-84np9brx	300	5	PML	PML	NNP
cord-002808-84np9brx	300	6	bodies	body	NNS
cord-002808-84np9brx	300	7	show	show	VBP
cord-002808-84np9brx	300	8	increased	increase	VBN
cord-002808-84np9brx	300	9	dynamics	dynamic	NNS
cord-002808-84np9brx	300	10	and	and	CC
cord-002808-84np9brx	300	11	disperse	disperse	VB
cord-002808-84np9brx	300	12	into	into	IN
cord-002808-84np9brx	300	13	the	the	DT
cord-002808-84np9brx	300	14	cytosol	cytosol	NN
cord-002808-84np9brx	300	15	during	during	IN
cord-002808-84np9brx	300	16	open	open	JJ
cord-002808-84np9brx	300	17	mitosis	mitosis	NN
cord-002808-84np9brx	300	18	.	.	.
cord-002808-84np9brx	301	1	Only	only	RB
cord-002808-84np9brx	301	2	after	after	IN
cord-002808-84np9brx	301	3	exit	exit	NN
cord-002808-84np9brx	301	4	from	from	IN
cord-002808-84np9brx	301	5	mitosis	mitosis	NN
cord-002808-84np9brx	301	6	and	and	CC
cord-002808-84np9brx	301	7	reformation	reformation	NN
cord-002808-84np9brx	301	8	of	of	IN
cord-002808-84np9brx	301	9	the	the	DT
cord-002808-84np9brx	301	10	nuclear	nuclear	JJ
cord-002808-84np9brx	301	11	envelope	envelope	NN
cord-002808-84np9brx	301	12	are	be	VBP
cord-002808-84np9brx	301	13	PML	PML	NNP
cord-002808-84np9brx	301	14	bodies	body	NNS
cord-002808-84np9brx	301	15	assembled	assemble	VBN
cord-002808-84np9brx	301	16	de	de	FW
cord-002808-84np9brx	301	17	novo	novo	NNP
cord-002808-84np9brx	301	18	,	,	,
cord-002808-84np9brx	301	19	and	and	CC
cord-002808-84np9brx	301	20	recruitment	recruitment	NN
cord-002808-84np9brx	301	21	of	of	IN
cord-002808-84np9brx	301	22	Daxx	Daxx	NNP
cord-002808-84np9brx	301	23	and	and	CC
cord-002808-84np9brx	301	24	Sp100	Sp100	NNP
cord-002808-84np9brx	301	25	is	be	VBZ
cord-002808-84np9brx	301	26	observed	observe	VBN
cord-002808-84np9brx	301	27	[	[	-LRB-
cord-002808-84np9brx	301	28	122	122	CD
cord-002808-84np9brx	301	29	]	]	-RRB-
cord-002808-84np9brx	301	30	.	.	.
cord-002808-84np9brx	302	1	Whether	whether	IN
cord-002808-84np9brx	302	2	L2	L2	NNP
cord-002808-84np9brx	302	3	recruits	recruit	VBZ
cord-002808-84np9brx	302	4	PML	PML	NNP
cord-002808-84np9brx	302	5	to	to	TO
cord-002808-84np9brx	302	6	nucleate	nucleate	VB
cord-002808-84np9brx	302	7	de	de	NNP
cord-002808-84np9brx	302	8	novo	novo	NNP
cord-002808-84np9brx	302	9	assembly	assembly	NNP
cord-002808-84np9brx	302	10	of	of	IN
cord-002808-84np9brx	302	11	PML	PML	NNP
cord-002808-84np9brx	302	12	bodies	body	NNS
cord-002808-84np9brx	302	13	in	in	IN
cord-002808-84np9brx	302	14	the	the	DT
cord-002808-84np9brx	302	15	vicinity	vicinity	NN
cord-002808-84np9brx	302	16	of	of	IN
cord-002808-84np9brx	302	17	the	the	DT
cord-002808-84np9brx	302	18	vDNA	vdna	JJ
cord-002808-84np9brx	302	19	after	after	IN
cord-002808-84np9brx	302	20	mitosis	mitosis	NN
cord-002808-84np9brx	302	21	or	or	CC
cord-002808-84np9brx	302	22	whether	whether	IN
cord-002808-84np9brx	302	23	the	the	DT
cord-002808-84np9brx	302	24	L2	L2	NNP
cord-002808-84np9brx	302	25	/	/	,
cord-002808-84np9brx	302	26	vDNA	vdna	RB
cord-002808-84np9brx	302	27	complex	complex	NNP
cord-002808-84np9brx	302	28	is	be	VBZ
cord-002808-84np9brx	302	29	targeted	target	VBN
cord-002808-84np9brx	302	30	to	to	IN
cord-002808-84np9brx	302	31	newly	newly	RB
cord-002808-84np9brx	302	32	formed	form	VBN
cord-002808-84np9brx	302	33	PML	PML	NNP
cord-002808-84np9brx	302	34	bodies	body	NNS
cord-002808-84np9brx	302	35	in	in	IN
cord-002808-84np9brx	302	36	early	early	JJ
cord-002808-84np9brx	302	37	G1	G1	NNP
cord-002808-84np9brx	302	38	remains	remain	VBZ
cord-002808-84np9brx	302	39	to	to	TO
cord-002808-84np9brx	302	40	be	be	VB
cord-002808-84np9brx	302	41	determined	determine	VBN
cord-002808-84np9brx	302	42	.	.	.
cord-002808-84np9brx	303	1	Likewise	likewise	RB
cord-002808-84np9brx	303	2	,	,	,
cord-002808-84np9brx	303	3	much	much	RB
cord-002808-84np9brx	303	4	remains	remain	VBZ
cord-002808-84np9brx	303	5	to	to	TO
cord-002808-84np9brx	303	6	be	be	VB
cord-002808-84np9brx	303	7	discovered	discover	VBN
cord-002808-84np9brx	303	8	regarding	regard	VBG
cord-002808-84np9brx	303	9	preferential	preferential	JJ
cord-002808-84np9brx	303	10	remodeling	remodeling	NN
cord-002808-84np9brx	303	11	of	of	IN
cord-002808-84np9brx	303	12	PML	PML	NNP
cord-002808-84np9brx	303	13	components	component	NNS
cord-002808-84np9brx	303	14	like	like	IN
cord-002808-84np9brx	303	15	Daxx	Daxx	NNP
cord-002808-84np9brx	303	16	and	and	CC
cord-002808-84np9brx	303	17	Sp100	sp100	NN
cord-002808-84np9brx	303	18	immediately	immediately	RB
cord-002808-84np9brx	303	19	after	after	IN
cord-002808-84np9brx	303	20	mitotic	mitotic	JJ
cord-002808-84np9brx	303	21	translocation	translocation	NN
cord-002808-84np9brx	303	22	of	of	IN
cord-002808-84np9brx	303	23	L2	L2	NNP
cord-002808-84np9brx	303	24	/	/	SYM
cord-002808-84np9brx	303	25	vDNA	vdna	NN
cord-002808-84np9brx	303	26	,	,	,
cord-002808-84np9brx	303	27	and	and	CC
cord-002808-84np9brx	303	28	the	the	DT
cord-002808-84np9brx	303	29	consequences	consequence	NNS
cord-002808-84np9brx	303	30	of	of	IN
cord-002808-84np9brx	303	31	this	this	DT
cord-002808-84np9brx	303	32	remodeling	remodeling	NN
cord-002808-84np9brx	303	33	for	for	IN
cord-002808-84np9brx	303	34	infection	infection	NN
cord-002808-84np9brx	303	35	,	,	,
cord-002808-84np9brx	303	36	immune	immune	JJ
cord-002808-84np9brx	303	37	evasion	evasion	NN
cord-002808-84np9brx	303	38	,	,	,
cord-002808-84np9brx	303	39	and	and	CC
cord-002808-84np9brx	303	40	viral	viral	JJ
cord-002808-84np9brx	303	41	persistence	persistence	NN
cord-002808-84np9brx	303	42	.	.	.
cord-002808-84np9brx	304	1	In	in	IN
cord-002808-84np9brx	304	2	addition	addition	NN
cord-002808-84np9brx	304	3	to	to	IN
cord-002808-84np9brx	304	4	role(s	role(s	NNP
cord-002808-84np9brx	304	5	)	)	-RRB-
cord-002808-84np9brx	304	6	in	in	IN
cord-002808-84np9brx	304	7	vDNA	vdna	JJ
cord-002808-84np9brx	304	8	packaging	packaging	NN
cord-002808-84np9brx	304	9	,	,	,
cord-002808-84np9brx	304	10	virion	virion	NN
cord-002808-84np9brx	304	11	assembly	assembly	NN
cord-002808-84np9brx	304	12	,	,	,
cord-002808-84np9brx	304	13	and	and	CC
cord-002808-84np9brx	304	14	particle	particle	NN
cord-002808-84np9brx	304	15	stability	stability	NN
cord-002808-84np9brx	304	16	[	[	-LRB-
cord-002808-84np9brx	304	17	11	11	CD
cord-002808-84np9brx	304	18	]	]	-RRB-
cord-002808-84np9brx	304	19	,	,	,
cord-002808-84np9brx	304	20	minor	minor	JJ
cord-002808-84np9brx	304	21	capsid	capsid	NN
cord-002808-84np9brx	304	22	protein	protein	NN
cord-002808-84np9brx	304	23	L2	L2	NNP
cord-002808-84np9brx	304	24	is	be	VBZ
cord-002808-84np9brx	304	25	tasked	task	VBN
cord-002808-84np9brx	304	26	with	with	IN
cord-002808-84np9brx	304	27	ensuring	ensure	VBG
cord-002808-84np9brx	304	28	nuclear	nuclear	JJ
cord-002808-84np9brx	304	29	delivery	delivery	NN
cord-002808-84np9brx	304	30	of	of	IN
cord-002808-84np9brx	304	31	the	the	DT
cord-002808-84np9brx	304	32	vDNA	vdna	NN
cord-002808-84np9brx	304	33	during	during	IN
cord-002808-84np9brx	304	34	HPV	HPV	NNP
cord-002808-84np9brx	304	35	infection	infection	NN
cord-002808-84np9brx	304	36	.	.	.
cord-002808-84np9brx	305	1	This	this	DT
cord-002808-84np9brx	305	2	feat	feat	NN
cord-002808-84np9brx	305	3	is	be	VBZ
cord-002808-84np9brx	305	4	accomplished	accomplish	VBN
cord-002808-84np9brx	305	5	via	via	IN
cord-002808-84np9brx	305	6	some	some	DT
cord-002808-84np9brx	305	7	remarkable	remarkable	JJ
cord-002808-84np9brx	305	8	means	mean	NNS
cord-002808-84np9brx	305	9	for	for	IN
cord-002808-84np9brx	305	10	a	a	DT
cord-002808-84np9brx	305	11	viral	viral	JJ
cord-002808-84np9brx	305	12	capsid	capsid	NN
cord-002808-84np9brx	305	13	protein	protein	NN
cord-002808-84np9brx	305	14	present	present	JJ
cord-002808-84np9brx	305	15	in	in	IN
cord-002808-84np9brx	305	16	low	low	JJ
cord-002808-84np9brx	305	17	copy	copy	NN
cord-002808-84np9brx	305	18	numbers	number	NNS
cord-002808-84np9brx	305	19	.	.	.
cord-002808-84np9brx	306	1	L2	L2	NNP
cord-002808-84np9brx	306	2	is	be	VBZ
cord-002808-84np9brx	306	3	able	able	JJ
cord-002808-84np9brx	306	4	to	to	TO
cord-002808-84np9brx	306	5	partition	partition	VB
cord-002808-84np9brx	306	6	vDNA	vdna	RB
cord-002808-84np9brx	306	7	away	away	RB
cord-002808-84np9brx	306	8	from	from	IN
cord-002808-84np9brx	306	9	degradative	degradative	NNP
cord-002808-84np9brx	306	10	endolysosomal	endolysosomal	NNP
cord-002808-84np9brx	306	11	compartments	compartment	NNS
cord-002808-84np9brx	306	12	,	,	,
cord-002808-84np9brx	306	13	instead	instead	RB
cord-002808-84np9brx	306	14	diverting	divert	VBG
cord-002808-84np9brx	306	15	it	-PRON-	PRP
cord-002808-84np9brx	306	16	to	to	IN
cord-002808-84np9brx	306	17	the	the	DT
cord-002808-84np9brx	306	18	TGN	TGN	NNP
cord-002808-84np9brx	306	19	.	.	.
cord-002808-84np9brx	307	1	L2	L2	NNP
cord-002808-84np9brx	307	2	does	do	VBZ
cord-002808-84np9brx	307	3	this	this	DT
cord-002808-84np9brx	307	4	by	by	IN
cord-002808-84np9brx	307	5	possessing	possess	VBG
cord-002808-84np9brx	307	6	properties	property	NNS
cord-002808-84np9brx	307	7	of	of	IN
cord-002808-84np9brx	307	8	an	an	DT
cord-002808-84np9brx	307	9	"	"	``
cord-002808-84np9brx	307	10	inducible	inducible	JJ
cord-002808-84np9brx	307	11	transmembrane	transmembrane	NN
cord-002808-84np9brx	307	12	"	"	''
cord-002808-84np9brx	307	13	protein	protein	NN
cord-002808-84np9brx	307	14	,	,	,
cord-002808-84np9brx	307	15	with	with	IN
cord-002808-84np9brx	307	16	the	the	DT
cord-002808-84np9brx	307	17	ability	ability	NN
cord-002808-84np9brx	307	18	to	to	TO
cord-002808-84np9brx	307	19	insert	insert	VB
cord-002808-84np9brx	307	20	into	into	IN
cord-002808-84np9brx	307	21	and	and	CC
cord-002808-84np9brx	307	22	protrude	protrude	VB
cord-002808-84np9brx	307	23	across	across	IN
cord-002808-84np9brx	307	24	local	local	JJ
cord-002808-84np9brx	307	25	vesicular	vesicular	JJ
cord-002808-84np9brx	307	26	membranes	membrane	NNS
cord-002808-84np9brx	307	27	using	use	VBG
cord-002808-84np9brx	307	28	a	a	DT
cord-002808-84np9brx	307	29	transmembrane	transmembrane	NN
cord-002808-84np9brx	307	30	-	-	HYPH
cord-002808-84np9brx	307	31	like	like	JJ
cord-002808-84np9brx	307	32	domain	domain	NN
cord-002808-84np9brx	307	33	.	.	.
cord-002808-84np9brx	308	1	Portions	portion	NNS
cord-002808-84np9brx	308	2	of	of	IN
cord-002808-84np9brx	308	3	L2	L2	NNP
cord-002808-84np9brx	308	4	containing	contain	VBG
cord-002808-84np9brx	308	5	conserved	conserved	JJ
cord-002808-84np9brx	308	6	sorting	sorting	NN
cord-002808-84np9brx	308	7	motifs	motif	NNS
cord-002808-84np9brx	308	8	are	be	VBP
cord-002808-84np9brx	308	9	exposed	expose	VBN
cord-002808-84np9brx	308	10	to	to	IN
cord-002808-84np9brx	308	11	the	the	DT
cord-002808-84np9brx	308	12	cytosol	cytosol	NN
cord-002808-84np9brx	308	13	,	,	,
cord-002808-84np9brx	308	14	recruiting	recruit	VBG
cord-002808-84np9brx	308	15	cellular	cellular	JJ
cord-002808-84np9brx	308	16	sorting	sorting	NN
cord-002808-84np9brx	308	17	factors	factor	NNS
cord-002808-84np9brx	308	18	that	that	WDT
cord-002808-84np9brx	308	19	dictate	dictate	VBP
cord-002808-84np9brx	308	20	retrograde	retrograde	JJ
cord-002808-84np9brx	308	21	trafficking	trafficking	NN
cord-002808-84np9brx	308	22	of	of	IN
cord-002808-84np9brx	308	23	L2	l2	NN
cord-002808-84np9brx	308	24	/	/	,
cord-002808-84np9brx	308	25	vDNA	vdna	NN
cord-002808-84np9brx	308	26	to	to	IN
cord-002808-84np9brx	308	27	the	the	DT
cord-002808-84np9brx	308	28	TGN	TGN	NNP
cord-002808-84np9brx	308	29	.	.	.
cord-002808-84np9brx	309	1	Upon	upon	IN
cord-002808-84np9brx	309	2	entry	entry	NN
cord-002808-84np9brx	309	3	into	into	IN
cord-002808-84np9brx	309	4	mitosis	mitosis	NN
cord-002808-84np9brx	309	5	,	,	,
cord-002808-84np9brx	309	6	the	the	DT
cord-002808-84np9brx	309	7	vesicular	vesicular	JJ
cord-002808-84np9brx	309	8	L2	L2	NNP
cord-002808-84np9brx	309	9	/	/	,
cord-002808-84np9brx	309	10	vDNA	vdna	RB
cord-002808-84np9brx	309	11	complex	complex	JJ
cord-002808-84np9brx	309	12	separates	separate	VBZ
cord-002808-84np9brx	309	13	from	from	IN
cord-002808-84np9brx	309	14	the	the	DT
cord-002808-84np9brx	309	15	dispersed	disperse	VBN
cord-002808-84np9brx	309	16	Golgi	Golgi	NNP
cord-002808-84np9brx	309	17	towards	towards	IN
cord-002808-84np9brx	309	18	the	the	DT
cord-002808-84np9brx	309	19	pericentriolar	pericentriolar	JJ
cord-002808-84np9brx	309	20	region	region	NN
cord-002808-84np9brx	309	21	and	and	CC
cord-002808-84np9brx	309	22	by	by	IN
cord-002808-84np9brx	309	23	metaphase	metaphase	NN
cord-002808-84np9brx	309	24	the	the	DT
cord-002808-84np9brx	309	25	vDNA	vdna	NN
cord-002808-84np9brx	309	26	can	can	MD
cord-002808-84np9brx	309	27	be	be	VB
cord-002808-84np9brx	309	28	seen	see	VBN
cord-002808-84np9brx	309	29	to	to	TO
cord-002808-84np9brx	309	30	be	be	VB
cord-002808-84np9brx	309	31	associated	associate	VBN
cord-002808-84np9brx	309	32	with	with	IN
cord-002808-84np9brx	309	33	condensed	condensed	JJ
cord-002808-84np9brx	309	34	chromosomes	chromosome	NNS
cord-002808-84np9brx	309	35	.	.	.
cord-002808-84np9brx	310	1	Whether	whether	IN
cord-002808-84np9brx	310	2	the	the	DT
cord-002808-84np9brx	310	3	visual	visual	JJ
cord-002808-84np9brx	310	4	association	association	NN
cord-002808-84np9brx	310	5	of	of	IN
cord-002808-84np9brx	310	6	vDNA	vdna	DT
cord-002808-84np9brx	310	7	with	with	IN
cord-002808-84np9brx	310	8	mitotic	mitotic	JJ
cord-002808-84np9brx	310	9	chromosomes	chromosome	NNS
cord-002808-84np9brx	310	10	represents	represent	VBZ
cord-002808-84np9brx	310	11	full	full	JJ
cord-002808-84np9brx	310	12	translocation	translocation	NN
cord-002808-84np9brx	310	13	of	of	IN
cord-002808-84np9brx	310	14	L2	L2	NNP
cord-002808-84np9brx	310	15	/	/	,
cord-002808-84np9brx	310	16	vDNA	vdna	RB
cord-002808-84np9brx	310	17	across	across	IN
cord-002808-84np9brx	310	18	limiting	limit	VBG
cord-002808-84np9brx	310	19	membranes	membrane	NNS
cord-002808-84np9brx	310	20	,	,	,
cord-002808-84np9brx	310	21	or	or	CC
cord-002808-84np9brx	310	22	simply	simply	RB
cord-002808-84np9brx	310	23	vDNA	vdna	RB
cord-002808-84np9brx	310	24	-	-	HYPH
cord-002808-84np9brx	310	25	filled	fill	VBN
cord-002808-84np9brx	310	26	post	post	NN
cord-002808-84np9brx	310	27	-	-	JJ
cord-002808-84np9brx	310	28	Golgi	golgi	JJ
cord-002808-84np9brx	310	29	vesicles	vesicle	NNS
cord-002808-84np9brx	310	30	bound	bind	VBN
cord-002808-84np9brx	310	31	to	to	IN
cord-002808-84np9brx	310	32	chromosomes	chromosome	NNS
cord-002808-84np9brx	310	33	,	,	,
cord-002808-84np9brx	310	34	remains	remain	VBZ
cord-002808-84np9brx	310	35	to	to	TO
cord-002808-84np9brx	310	36	be	be	VB
cord-002808-84np9brx	310	37	shown	show	VBN
cord-002808-84np9brx	310	38	.	.	.
cord-002808-84np9brx	311	1	Together	together	RB
cord-002808-84np9brx	311	2	with	with	IN
cord-002808-84np9brx	311	3	recent	recent	JJ
cord-002808-84np9brx	311	4	work	work	NN
cord-002808-84np9brx	311	5	on	on	IN
cord-002808-84np9brx	311	6	the	the	DT
cord-002808-84np9brx	311	7	chromatin	chromatin	NN
cord-002808-84np9brx	311	8	-	-	HYPH
cord-002808-84np9brx	311	9	binding	bind	VBG
cord-002808-84np9brx	311	10	abilities	ability	NNS
cord-002808-84np9brx	311	11	of	of	IN
cord-002808-84np9brx	311	12	L2	l2	NN
cord-002808-84np9brx	311	13	,	,	,
cord-002808-84np9brx	311	14	translocation	translocation	NN
cord-002808-84np9brx	311	15	studies	study	NNS
cord-002808-84np9brx	311	16	using	use	VBG
cord-002808-84np9brx	311	17	a	a	DT
cord-002808-84np9brx	311	18	novel	novel	JJ
cord-002808-84np9brx	311	19	BirA	bira	NN
cord-002808-84np9brx	311	20	-	-	HYPH
cord-002808-84np9brx	311	21	based	base	VBN
cord-002808-84np9brx	311	22	approach	approach	NN
cord-002808-84np9brx	311	23	suggest	suggest	VBP
cord-002808-84np9brx	311	24	that	that	IN
cord-002808-84np9brx	311	25	chromatin	chromatin	NN
cord-002808-84np9brx	311	26	binding	binding	NN
cord-002808-84np9brx	311	27	is	be	VBZ
cord-002808-84np9brx	311	28	necessary	necessary	JJ
cord-002808-84np9brx	311	29	for	for	IN
cord-002808-84np9brx	311	30	translocation	translocation	NN
cord-002808-84np9brx	311	31	.	.	.
cord-002808-84np9brx	312	1	Timecourse	timecourse	NN
cord-002808-84np9brx	312	2	experiments	experiment	NNS
cord-002808-84np9brx	312	3	with	with	IN
cord-002808-84np9brx	312	4	synchronized	synchronized	JJ
cord-002808-84np9brx	312	5	cells	cell	NNS
cord-002808-84np9brx	312	6	suggest	suggest	VBP
cord-002808-84np9brx	312	7	that	that	IN
cord-002808-84np9brx	312	8	translocation	translocation	NN
cord-002808-84np9brx	312	9	is	be	VBZ
cord-002808-84np9brx	312	10	concurrent	concurrent	JJ
cord-002808-84np9brx	312	11	with	with	IN
cord-002808-84np9brx	312	12	or	or	CC
cord-002808-84np9brx	312	13	slightly	slightly	RB
cord-002808-84np9brx	312	14	after	after	IN
cord-002808-84np9brx	312	15	the	the	DT
cord-002808-84np9brx	312	16	onset	onset	NN
cord-002808-84np9brx	312	17	of	of	IN
cord-002808-84np9brx	312	18	mitosis	mitosis	NN
cord-002808-84np9brx	312	19	.	.	.
cord-002808-84np9brx	313	1	In	in	IN
cord-002808-84np9brx	313	2	contrast	contrast	NN
cord-002808-84np9brx	313	3	,	,	,
cord-002808-84np9brx	313	4	sequential	sequential	JJ
cord-002808-84np9brx	313	5	fluor	fluor	NNP
cord-002808-84np9brx	313	6	-	-	HYPH
cord-002808-84np9brx	313	7	azide	azide	NN
cord-002808-84np9brx	313	8	conjugation	conjugation	NN
cord-002808-84np9brx	313	9	of	of	IN
cord-002808-84np9brx	313	10	EdU	edu	NN
cord-002808-84np9brx	313	11	-	-	HYPH
cord-002808-84np9brx	313	12	labeled	label	VBN
cord-002808-84np9brx	313	13	vDNA	vdna	RB
cord-002808-84np9brx	313	14	after	after	IN
cord-002808-84np9brx	313	15	differential	differential	JJ
cord-002808-84np9brx	313	16	detergent	detergent	NN
cord-002808-84np9brx	313	17	permeabilization	permeabilization	NN
cord-002808-84np9brx	313	18	suggests	suggest	VBZ
cord-002808-84np9brx	313	19	that	that	IN
cord-002808-84np9brx	313	20	translocation	translocation	NN
cord-002808-84np9brx	313	21	,	,	,
cord-002808-84np9brx	313	22	as	as	IN
cord-002808-84np9brx	313	23	defined	define	VBN
cord-002808-84np9brx	313	24	by	by	IN
cord-002808-84np9brx	313	25	the	the	DT
cord-002808-84np9brx	313	26	liberation	liberation	NN
cord-002808-84np9brx	313	27	of	of	IN
cord-002808-84np9brx	313	28	vDNA	vdna	NN
cord-002808-84np9brx	313	29	from	from	IN
cord-002808-84np9brx	313	30	membrane	membrane	NN
cord-002808-84np9brx	313	31	-	-	HYPH
cord-002808-84np9brx	313	32	bound	bind	VBN
cord-002808-84np9brx	313	33	compartments	compartment	NNS
cord-002808-84np9brx	313	34	,	,	,
cord-002808-84np9brx	313	35	occurs	occur	VBZ
cord-002808-84np9brx	313	36	post	post	NN
cord-002808-84np9brx	313	37	-	-	JJ
cord-002808-84np9brx	313	38	mitosis	mitosis	NN
cord-002808-84np9brx	313	39	in	in	IN
cord-002808-84np9brx	313	40	G1	G1	NNP
cord-002808-84np9brx	313	41	.	.	.
cord-002808-84np9brx	314	1	Regardless	regardless	RB
cord-002808-84np9brx	314	2	of	of	IN
cord-002808-84np9brx	314	3	the	the	DT
cord-002808-84np9brx	314	4	specific	specific	JJ
cord-002808-84np9brx	314	5	mechanisms	mechanism	NNS
cord-002808-84np9brx	314	6	and	and	CC
cord-002808-84np9brx	314	7	timing	timing	NN
cord-002808-84np9brx	314	8	of	of	IN
cord-002808-84np9brx	314	9	translocation	translocation	NN
cord-002808-84np9brx	314	10	,	,	,
cord-002808-84np9brx	314	11	L2	L2	NNP
cord-002808-84np9brx	314	12	/	/	,
cord-002808-84np9brx	314	13	vDNA	vdna	RB
cord-002808-84np9brx	314	14	localizes	localize	VBZ
cord-002808-84np9brx	314	15	to	to	IN
cord-002808-84np9brx	314	16	PML	PML	NNP
cord-002808-84np9brx	314	17	bodies	body	NNS
cord-002808-84np9brx	314	18	of	of	IN
cord-002808-84np9brx	314	19	the	the	DT
cord-002808-84np9brx	314	20	daughter	daughter	NN
cord-002808-84np9brx	314	21	cells	cell	NNS
cord-002808-84np9brx	314	22	and	and	CC
cord-002808-84np9brx	314	23	likely	likely	JJ
cord-002808-84np9brx	314	24	functions	function	NNS
cord-002808-84np9brx	314	25	to	to	TO
cord-002808-84np9brx	314	26	promote	promote	VB
cord-002808-84np9brx	314	27	efficient	efficient	JJ
cord-002808-84np9brx	314	28	viral	viral	JJ
cord-002808-84np9brx	314	29	gene	gene	NN
cord-002808-84np9brx	314	30	expression	expression	NN
cord-002808-84np9brx	314	31	.	.	.
cord-002808-84np9brx	315	1	Additional	additional	JJ
cord-002808-84np9brx	315	2	efforts	effort	NNS
cord-002808-84np9brx	315	3	are	be	VBP
cord-002808-84np9brx	315	4	needed	need	VBN
cord-002808-84np9brx	315	5	to	to	TO
cord-002808-84np9brx	315	6	further	further	RB
cord-002808-84np9brx	315	7	define	define	VB
cord-002808-84np9brx	315	8	the	the	DT
cord-002808-84np9brx	315	9	mechanisms	mechanism	NNS
cord-002808-84np9brx	315	10	of	of	IN
cord-002808-84np9brx	315	11	L2	L2	NNP
cord-002808-84np9brx	315	12	's	's	POS
cord-002808-84np9brx	315	13	remarkable	remarkable	JJ
cord-002808-84np9brx	315	14	abilities	ability	NNS
cord-002808-84np9brx	315	15	.	.	.
cord-002808-84np9brx	316	1	Structural	structural	JJ
cord-002808-84np9brx	316	2	studies	study	NNS
cord-002808-84np9brx	316	3	are	be	VBP
cord-002808-84np9brx	316	4	needed	need	VBN
cord-002808-84np9brx	316	5	to	to	TO
cord-002808-84np9brx	316	6	understand	understand	VB
cord-002808-84np9brx	316	7	the	the	DT
cord-002808-84np9brx	316	8	nature	nature	NN
cord-002808-84np9brx	316	9	of	of	IN
cord-002808-84np9brx	316	10	the	the	DT
cord-002808-84np9brx	316	11	L2	L2	NNP
cord-002808-84np9brx	316	12	/	/	,
cord-002808-84np9brx	316	13	vDNA	vdna	RB
cord-002808-84np9brx	316	14	complex	complex	NN
cord-002808-84np9brx	316	15	within	within	IN
cord-002808-84np9brx	316	16	viral	viral	JJ
cord-002808-84np9brx	316	17	particles	particle	NNS
cord-002808-84np9brx	316	18	,	,	,
cord-002808-84np9brx	316	19	the	the	DT
cord-002808-84np9brx	316	20	molecular	molecular	JJ
cord-002808-84np9brx	316	21	basis	basis	NN
cord-002808-84np9brx	316	22	underlying	underlie	VBG
cord-002808-84np9brx	316	23	the	the	DT
cord-002808-84np9brx	316	24	requirement	requirement	NN
cord-002808-84np9brx	316	25	for	for	IN
cord-002808-84np9brx	316	26	furin	furin	NN
cord-002808-84np9brx	316	27	,	,	,
cord-002808-84np9brx	316	28	the	the	DT
cord-002808-84np9brx	316	29	consequences	consequence	NNS
cord-002808-84np9brx	316	30	of	of	IN
cord-002808-84np9brx	316	31	cleavage	cleavage	NN
cord-002808-84np9brx	316	32	,	,	,
cord-002808-84np9brx	316	33	and	and	CC
cord-002808-84np9brx	316	34	the	the	DT
cord-002808-84np9brx	316	35	mechanisms	mechanism	NNS
cord-002808-84np9brx	316	36	of	of	IN
cord-002808-84np9brx	316	37	L2-membrane	L2-membrane	NNP
cord-002808-84np9brx	316	38	interaction	interaction	NN
cord-002808-84np9brx	316	39	.	.	.
cord-002808-84np9brx	317	1	Further	further	JJ
cord-002808-84np9brx	317	2	work	work	NN
cord-002808-84np9brx	317	3	is	be	VBZ
cord-002808-84np9brx	317	4	needed	need	VBN
cord-002808-84np9brx	317	5	to	to	TO
cord-002808-84np9brx	317	6	understand	understand	VB
cord-002808-84np9brx	317	7	and	and	CC
cord-002808-84np9brx	317	8	define	define	VB
cord-002808-84np9brx	317	9	the	the	DT
cord-002808-84np9brx	317	10	nature	nature	NN
cord-002808-84np9brx	317	11	of	of	IN
cord-002808-84np9brx	317	12	L2	l2	NN
cord-002808-84np9brx	317	13	protrusion	protrusion	NN
cord-002808-84np9brx	317	14	through	through	IN
cord-002808-84np9brx	317	15	limiting	limit	VBG
cord-002808-84np9brx	317	16	membranes	membrane	NNS
cord-002808-84np9brx	317	17	,	,	,
cord-002808-84np9brx	317	18	specifically	specifically	RB
cord-002808-84np9brx	317	19	the	the	DT
cord-002808-84np9brx	317	20	topology	topology	NN
cord-002808-84np9brx	317	21	of	of	IN
cord-002808-84np9brx	317	22	L2	l2	NN
cord-002808-84np9brx	317	23	within	within	IN
cord-002808-84np9brx	317	24	these	these	DT
cord-002808-84np9brx	317	25	membranes	membrane	NNS
cord-002808-84np9brx	317	26	,	,	,
cord-002808-84np9brx	317	27	and	and	CC
cord-002808-84np9brx	317	28	to	to	IN
cord-002808-84np9brx	317	29	identity	identity	NN
cord-002808-84np9brx	317	30	any	any	DT
cord-002808-84np9brx	317	31	host	host	NN
cord-002808-84np9brx	317	32	proteins	protein	NNS
cord-002808-84np9brx	317	33	that	that	WDT
cord-002808-84np9brx	317	34	may	may	MD
cord-002808-84np9brx	317	35	be	be	VB
cord-002808-84np9brx	317	36	necessary	necessary	JJ
cord-002808-84np9brx	317	37	for	for	IN
cord-002808-84np9brx	317	38	L2-membrane	L2-membrane	NNP
cord-002808-84np9brx	317	39	insertion	insertion	NN
cord-002808-84np9brx	317	40	and	and	CC
cord-002808-84np9brx	317	41	protrusion	protrusion	NN
cord-002808-84np9brx	317	42	.	.	.
cord-002808-84np9brx	318	1	More	More	JJR
cord-002808-84np9brx	318	2	work	work	NN
cord-002808-84np9brx	318	3	is	be	VBZ
cord-002808-84np9brx	318	4	necessary	necessary	JJ
cord-002808-84np9brx	318	5	to	to	TO
cord-002808-84np9brx	318	6	identify	identify	VB
cord-002808-84np9brx	318	7	the	the	DT
cord-002808-84np9brx	318	8	nature	nature	NN
cord-002808-84np9brx	318	9	of	of	IN
cord-002808-84np9brx	318	10	the	the	DT
cord-002808-84np9brx	318	11	post	post	JJ
cord-002808-84np9brx	318	12	-	-	JJ
cord-002808-84np9brx	318	13	Golgi	golgi	JJ
cord-002808-84np9brx	318	14	vesicles	vesicle	NNS
cord-002808-84np9brx	318	15	in	in	IN
cord-002808-84np9brx	318	16	which	which	WDT
cord-002808-84np9brx	318	17	L2	L2	NNP
cord-002808-84np9brx	318	18	resides	reside	VBZ
cord-002808-84np9brx	318	19	upon	upon	IN
cord-002808-84np9brx	318	20	entry	entry	NN
cord-002808-84np9brx	318	21	into	into	IN
cord-002808-84np9brx	318	22	mitosis	mitosis	NN
cord-002808-84np9brx	318	23	,	,	,
cord-002808-84np9brx	318	24	and	and	CC
cord-002808-84np9brx	318	25	again	again	RB
cord-002808-84np9brx	318	26	to	to	TO
cord-002808-84np9brx	318	27	define	define	VB
cord-002808-84np9brx	318	28	the	the	DT
cord-002808-84np9brx	318	29	host	host	NN
cord-002808-84np9brx	318	30	proteins	protein	NNS
cord-002808-84np9brx	318	31	that	that	WDT
cord-002808-84np9brx	318	32	may	may	MD
cord-002808-84np9brx	318	33	be	be	VB
cord-002808-84np9brx	318	34	interacting	interact	VBG
cord-002808-84np9brx	318	35	with	with	IN
cord-002808-84np9brx	318	36	L2	L2	NNP
cord-002808-84np9brx	318	37	to	to	TO
cord-002808-84np9brx	318	38	enable	enable	VB
cord-002808-84np9brx	318	39	subcellular	subcellular	JJ
cord-002808-84np9brx	318	40	transport	transport	NN
cord-002808-84np9brx	318	41	of	of	IN
cord-002808-84np9brx	318	42	these	these	DT
cord-002808-84np9brx	318	43	compartments	compartment	NNS
cord-002808-84np9brx	318	44	and	and	CC
cord-002808-84np9brx	318	45	eventual	eventual	JJ
cord-002808-84np9brx	318	46	translocation	translocation	NN
cord-002808-84np9brx	318	47	.	.	.
cord-002808-84np9brx	319	1	Elucidation	elucidation	NN
cord-002808-84np9brx	319	2	of	of	IN
cord-002808-84np9brx	319	3	the	the	DT
cord-002808-84np9brx	319	4	timing	timing	NN
cord-002808-84np9brx	319	5	and	and	CC
cord-002808-84np9brx	319	6	mechanisms	mechanism	NNS
cord-002808-84np9brx	319	7	of	of	IN
cord-002808-84np9brx	319	8	actual	actual	JJ
cord-002808-84np9brx	319	9	L2	l2	NN
cord-002808-84np9brx	319	10	/	/	,
cord-002808-84np9brx	319	11	vDNA	vdna	NN
cord-002808-84np9brx	319	12	translocation	translocation	NN
cord-002808-84np9brx	319	13	will	will	MD
cord-002808-84np9brx	319	14	require	require	VB
cord-002808-84np9brx	319	15	new	new	JJ
cord-002808-84np9brx	319	16	approaches	approach	NNS
cord-002808-84np9brx	319	17	.	.	.
cord-002808-84np9brx	320	1	Finally	finally	RB
cord-002808-84np9brx	320	2	,	,	,
cord-002808-84np9brx	320	3	the	the	DT
cord-002808-84np9brx	320	4	precise	precise	JJ
cord-002808-84np9brx	320	5	role(s	role(s	NNP
cord-002808-84np9brx	320	6	)	)	-RRB-
cord-002808-84np9brx	320	7	of	of	IN
cord-002808-84np9brx	320	8	virion	virion	NN
cord-002808-84np9brx	320	9	-	-	HYPH
cord-002808-84np9brx	320	10	derived	derive	VBN
cord-002808-84np9brx	320	11	L2	l2	NN
cord-002808-84np9brx	320	12	in	in	IN
cord-002808-84np9brx	320	13	the	the	DT
cord-002808-84np9brx	320	14	remodeling	remodeling	NN
cord-002808-84np9brx	320	15	of	of	IN
cord-002808-84np9brx	320	16	PML	PML	NNP
cord-002808-84np9brx	320	17	bodies	body	NNS
cord-002808-84np9brx	320	18	,	,	,
cord-002808-84np9brx	320	19	establishment	establishment	NN
cord-002808-84np9brx	320	20	of	of	IN
cord-002808-84np9brx	320	21	infection	infection	NN
cord-002808-84np9brx	320	22	,	,	,
cord-002808-84np9brx	320	23	initial	initial	JJ
cord-002808-84np9brx	320	24	viral	viral	JJ
cord-002808-84np9brx	320	25	gene	gene	NN
cord-002808-84np9brx	320	26	expression	expression	NN
cord-002808-84np9brx	320	27	,	,	,
cord-002808-84np9brx	320	28	and	and	CC
cord-002808-84np9brx	320	29	potential	potential	JJ
cord-002808-84np9brx	320	30	immunoevasion	immunoevasion	NN
cord-002808-84np9brx	320	31	all	all	DT
cord-002808-84np9brx	320	32	represent	represent	VBP
cord-002808-84np9brx	320	33	exciting	exciting	JJ
cord-002808-84np9brx	320	34	avenues	avenue	NNS
cord-002808-84np9brx	320	35	of	of	IN
cord-002808-84np9brx	320	36	future	future	JJ
cord-002808-84np9brx	320	37	endeavors	endeavor	NNS
cord-002808-84np9brx	320	38	.	.	.
cord-002808-84np9brx	321	1	Deep	deep	JJ
cord-002808-84np9brx	321	2	sequencing	sequencing	NN
cord-002808-84np9brx	321	3	extends	extend	VBZ
cord-002808-84np9brx	321	4	the	the	DT
cord-002808-84np9brx	321	5	diversity	diversity	NN
cord-002808-84np9brx	321	6	of	of	IN
cord-002808-84np9brx	321	7	human	human	JJ
cord-002808-84np9brx	321	8	papillomaviruses	papillomaviruse	NNS
cord-002808-84np9brx	321	9	in	in	IN
cord-002808-84np9brx	321	10	human	human	JJ
cord-002808-84np9brx	321	11	skin	skin	NN
cord-002808-84np9brx	321	12	Evolution	evolution	NN
cord-002808-84np9brx	321	13	of	of	IN
cord-002808-84np9brx	321	14	the	the	DT
cord-002808-84np9brx	321	15	papillomaviridae	papillomaviridae	NN
cord-002808-84np9brx	322	1	The	the	DT
cord-002808-84np9brx	322	2	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	322	3	episteme	episteme	FW
cord-002808-84np9brx	322	4	:	:	:
cord-002808-84np9brx	322	5	A	a	DT
cord-002808-84np9brx	322	6	major	major	JJ
cord-002808-84np9brx	322	7	update	update	NN
cord-002808-84np9brx	322	8	to	to	IN
cord-002808-84np9brx	322	9	the	the	DT
cord-002808-84np9brx	322	10	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	322	11	sequence	sequence	NN
cord-002808-84np9brx	322	12	database	database	NN
cord-002808-84np9brx	322	13	The	the	DT
cord-002808-84np9brx	322	14	biology	biology	NN
cord-002808-84np9brx	322	15	and	and	CC
cord-002808-84np9brx	322	16	life	life	NN
cord-002808-84np9brx	322	17	-	-	HYPH
cord-002808-84np9brx	322	18	cycle	cycle	NN
cord-002808-84np9brx	322	19	of	of	IN
cord-002808-84np9brx	322	20	human	human	JJ
cord-002808-84np9brx	322	21	papillomaviruses	papillomaviruse	NNS
cord-002808-84np9brx	322	22	Global	global	JJ
cord-002808-84np9brx	322	23	burden	burden	NN
cord-002808-84np9brx	322	24	of	of	IN
cord-002808-84np9brx	322	25	human	human	JJ
cord-002808-84np9brx	322	26	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	322	27	and	and	CC
cord-002808-84np9brx	322	28	related	related	JJ
cord-002808-84np9brx	322	29	diseases	disease	NNS
cord-002808-84np9brx	323	1	Carcinogenic	carcinogenic	JJ
cord-002808-84np9brx	323	2	human	human	JJ
cord-002808-84np9brx	323	3	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	323	4	infection	infection	NN
cord-002808-84np9brx	323	5	Arrangement	Arrangement	NNP
cord-002808-84np9brx	323	6	of	of	IN
cord-002808-84np9brx	323	7	L2	L2	NNP
cord-002808-84np9brx	323	8	within	within	IN
cord-002808-84np9brx	323	9	the	the	DT
cord-002808-84np9brx	323	10	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	323	11	capsid	capsid	NN
cord-002808-84np9brx	323	12	Antibody	Antibody	NNP
cord-002808-84np9brx	323	13	competition	competition	NN
cord-002808-84np9brx	323	14	reveals	reveal	VBZ
cord-002808-84np9brx	323	15	surface	surface	NN
cord-002808-84np9brx	323	16	location	location	NN
cord-002808-84np9brx	323	17	of	of	IN
cord-002808-84np9brx	323	18	HPV	HPV	NNP
cord-002808-84np9brx	323	19	L2	L2	NNP
cord-002808-84np9brx	323	20	minor	minor	JJ
cord-002808-84np9brx	323	21	capsid	capsid	NN
cord-002808-84np9brx	323	22	protein	protein	NN
cord-002808-84np9brx	323	23	residues	residue	VBZ
cord-002808-84np9brx	323	24	17	17	CD
cord-002808-84np9brx	323	25	-	-	SYM
cord-002808-84np9brx	323	26	36	36	CD
cord-002808-84np9brx	323	27	Cross	cross	NN
cord-002808-84np9brx	323	28	-	-	NN
cord-002808-84np9brx	323	29	neutralization	neutralization	NN
cord-002808-84np9brx	323	30	of	of	IN
cord-002808-84np9brx	323	31	cutaneous	cutaneous	JJ
cord-002808-84np9brx	323	32	and	and	CC
cord-002808-84np9brx	323	33	mucosal	mucosal	JJ
cord-002808-84np9brx	323	34	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	323	35	types	type	NNS
cord-002808-84np9brx	323	36	with	with	IN
cord-002808-84np9brx	323	37	anti	anti	JJ
cord-002808-84np9brx	323	38	-	-	JJ
cord-002808-84np9brx	323	39	sera	sera	JJ
cord-002808-84np9brx	323	40	to	to	IN
cord-002808-84np9brx	323	41	the	the	DT
cord-002808-84np9brx	323	42	amino	amino	NN
cord-002808-84np9brx	323	43	terminus	terminus	NN
cord-002808-84np9brx	323	44	of	of	IN
cord-002808-84np9brx	323	45	L2	L2	NNP
cord-002808-84np9brx	323	46	Neutralization	Neutralization	NNP
cord-002808-84np9brx	323	47	of	of	IN
cord-002808-84np9brx	323	48	HPV16	HPV16	NNP
cord-002808-84np9brx	323	49	,	,	,
cord-002808-84np9brx	323	50	18	18	CD
cord-002808-84np9brx	323	51	,	,	,
cord-002808-84np9brx	323	52	31	31	CD
cord-002808-84np9brx	323	53	,	,	,
cord-002808-84np9brx	323	54	and	and	CC
cord-002808-84np9brx	323	55	58	58	CD
cord-002808-84np9brx	323	56	pseudovirions	pseudovirion	NNS
cord-002808-84np9brx	323	57	with	with	IN
cord-002808-84np9brx	323	58	antisera	antisera	NN
cord-002808-84np9brx	323	59	induced	induce	VBN
cord-002808-84np9brx	323	60	by	by	IN
cord-002808-84np9brx	323	61	immunizing	immunize	VBG
cord-002808-84np9brx	323	62	rabbits	rabbit	NNS
cord-002808-84np9brx	323	63	with	with	IN
cord-002808-84np9brx	323	64	synthetic	synthetic	JJ
cord-002808-84np9brx	323	65	peptides	peptide	NNS
cord-002808-84np9brx	323	66	representing	represent	VBG
cord-002808-84np9brx	323	67	segments	segment	NNS
cord-002808-84np9brx	323	68	of	of	IN
cord-002808-84np9brx	323	69	the	the	DT
cord-002808-84np9brx	323	70	HPV16	hpv16	NN
cord-002808-84np9brx	323	71	minor	minor	JJ
cord-002808-84np9brx	323	72	capsid	capsid	NN
cord-002808-84np9brx	323	73	protein	protein	NN
cord-002808-84np9brx	323	74	L2	L2	NNP
cord-002808-84np9brx	323	75	surface	surface	NN
cord-002808-84np9brx	323	76	region	region	NN
cord-002808-84np9brx	323	77	L2	L2	NNP
cord-002808-84np9brx	323	78	,	,	,
cord-002808-84np9brx	323	79	the	the	DT
cord-002808-84np9brx	323	80	minor	minor	JJ
cord-002808-84np9brx	323	81	capsid	capsid	NN
cord-002808-84np9brx	323	82	protein	protein	NN
cord-002808-84np9brx	323	83	of	of	IN
cord-002808-84np9brx	323	84	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	324	1	The	the	DT
cord-002808-84np9brx	324	2	L2	L2	NNP
cord-002808-84np9brx	324	3	minor	minor	JJ
cord-002808-84np9brx	324	4	capsid	capsid	NN
cord-002808-84np9brx	324	5	protein	protein	NN
cord-002808-84np9brx	324	6	of	of	IN
cord-002808-84np9brx	324	7	low	low	JJ
cord-002808-84np9brx	324	8	-	-	HYPH
cord-002808-84np9brx	324	9	risk	risk	NN
cord-002808-84np9brx	324	10	human	human	JJ
cord-002808-84np9brx	324	11	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	324	12	type	type	NN
cord-002808-84np9brx	324	13	11	11	CD
cord-002808-84np9brx	324	14	interacts	interact	VBZ
cord-002808-84np9brx	324	15	with	with	IN
cord-002808-84np9brx	324	16	host	host	NN
cord-002808-84np9brx	324	17	nuclear	nuclear	JJ
cord-002808-84np9brx	324	18	import	import	NN
cord-002808-84np9brx	324	19	receptors	receptor	NNS
cord-002808-84np9brx	324	20	and	and	CC
cord-002808-84np9brx	324	21	viral	viral	JJ
cord-002808-84np9brx	324	22	DNA	dna	NN
cord-002808-84np9brx	325	1	The	the	DT
cord-002808-84np9brx	325	2	positively	positively	RB
cord-002808-84np9brx	325	3	charged	charge	VBN
cord-002808-84np9brx	325	4	termini	terminus	NNS
cord-002808-84np9brx	325	5	of	of	IN
cord-002808-84np9brx	325	6	L2	L2	NNP
cord-002808-84np9brx	325	7	minor	minor	JJ
cord-002808-84np9brx	325	8	capsid	capsid	NN
cord-002808-84np9brx	325	9	protein	protein	NN
cord-002808-84np9brx	325	10	required	require	VBN
cord-002808-84np9brx	325	11	for	for	IN
cord-002808-84np9brx	325	12	bovine	bovine	JJ
cord-002808-84np9brx	325	13	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	325	14	infection	infection	NN
cord-002808-84np9brx	325	15	function	function	NN
cord-002808-84np9brx	325	16	separately	separately	RB
cord-002808-84np9brx	325	17	in	in	IN
cord-002808-84np9brx	325	18	nuclear	nuclear	JJ
cord-002808-84np9brx	325	19	import	import	NN
cord-002808-84np9brx	325	20	and	and	CC
cord-002808-84np9brx	325	21	DNA	DNA	NNP
cord-002808-84np9brx	325	22	binding	bind	VBG
cord-002808-84np9brx	325	23	Nuclear	nuclear	JJ
cord-002808-84np9brx	325	24	import	import	NN
cord-002808-84np9brx	325	25	strategies	strategy	NNS
cord-002808-84np9brx	325	26	of	of	IN
cord-002808-84np9brx	325	27	high	high	JJ
cord-002808-84np9brx	325	28	-	-	HYPH
cord-002808-84np9brx	325	29	risk	risk	NN
cord-002808-84np9brx	325	30	HPV18	HPV18	NNP
cord-002808-84np9brx	325	31	L2	L2	NNP
cord-002808-84np9brx	325	32	minor	minor	JJ
cord-002808-84np9brx	325	33	capsid	capsid	NN
cord-002808-84np9brx	325	34	protein	protein	NN
cord-002808-84np9brx	325	35	Interaction	Interaction	NNP
cord-002808-84np9brx	325	36	of	of	IN
cord-002808-84np9brx	325	37	human	human	JJ
cord-002808-84np9brx	325	38	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	325	39	(	(	-LRB-
cord-002808-84np9brx	325	40	HPV	HPV	NNP
cord-002808-84np9brx	325	41	)	)	-RRB-
cord-002808-84np9brx	325	42	type	type	NN
cord-002808-84np9brx	325	43	16	16	CD
cord-002808-84np9brx	325	44	capsid	capsid	NN
cord-002808-84np9brx	325	45	proteins	protein	NNS
cord-002808-84np9brx	325	46	with	with	IN
cord-002808-84np9brx	325	47	HPV	HPV	NNP
cord-002808-84np9brx	325	48	DNA	DNA	NNP
cord-002808-84np9brx	325	49	requires	require	VBZ
cord-002808-84np9brx	325	50	an	an	DT
cord-002808-84np9brx	325	51	intact	intact	JJ
cord-002808-84np9brx	325	52	L2	L2	NNP
cord-002808-84np9brx	325	53	N	N	NNP
cord-002808-84np9brx	325	54	-	-	HYPH
cord-002808-84np9brx	325	55	terminal	terminal	NN
cord-002808-84np9brx	325	56	sequence	sequence	NN
cord-002808-84np9brx	325	57	Production	production	NN
cord-002808-84np9brx	325	58	of	of	IN
cord-002808-84np9brx	325	59	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	325	60	-	-	HYPH
cord-002808-84np9brx	325	61	based	base	VBN
cord-002808-84np9brx	325	62	gene	gene	NN
cord-002808-84np9brx	325	63	transfer	transfer	NN
cord-002808-84np9brx	325	64	vectors	vector	NNS
cord-002808-84np9brx	325	65	Papillomavirus	papillomavirus	NN
cord-002808-84np9brx	325	66	infectious	infectious	JJ
cord-002808-84np9brx	325	67	pathways	pathway	NNS
cord-002808-84np9brx	325	68	:	:	:
cord-002808-84np9brx	326	1	A	a	DT
cord-002808-84np9brx	326	2	comparison	comparison	NN
cord-002808-84np9brx	326	3	of	of	IN
cord-002808-84np9brx	326	4	systems	system	NNS
cord-002808-84np9brx	326	5	HPV	HPV	NNP
cord-002808-84np9brx	326	6	entry	entry	NN
cord-002808-84np9brx	326	7	into	into	IN
cord-002808-84np9brx	326	8	cells	cell	NNS
cord-002808-84np9brx	326	9	Concepts	concept	NNS
cord-002808-84np9brx	326	10	of	of	IN
cord-002808-84np9brx	326	11	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	326	12	entry	entry	NN
cord-002808-84np9brx	326	13	into	into	IN
cord-002808-84np9brx	326	14	host	host	NN
cord-002808-84np9brx	326	15	cells	cell	NNS
cord-002808-84np9brx	326	16	Cruising	cruise	VBG
cord-002808-84np9brx	326	17	the	the	DT
cord-002808-84np9brx	326	18	cellular	cellular	JJ
cord-002808-84np9brx	326	19	highways	highway	NNS
cord-002808-84np9brx	326	20	:	:	:
cord-002808-84np9brx	326	21	How	how	WRB
cord-002808-84np9brx	326	22	human	human	JJ
cord-002808-84np9brx	326	23	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	326	24	travels	travel	VBZ
cord-002808-84np9brx	326	25	from	from	IN
cord-002808-84np9brx	326	26	the	the	DT
cord-002808-84np9brx	326	27	surface	surface	NN
cord-002808-84np9brx	326	28	to	to	IN
cord-002808-84np9brx	326	29	the	the	DT
cord-002808-84np9brx	326	30	nucleus	nucleus	NN
cord-002808-84np9brx	326	31	Cleavage	cleavage	NN
cord-002808-84np9brx	326	32	of	of	IN
cord-002808-84np9brx	326	33	the	the	DT
cord-002808-84np9brx	326	34	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	326	35	minor	minor	JJ
cord-002808-84np9brx	326	36	capsid	capsid	NN
cord-002808-84np9brx	326	37	protein	protein	NN
cord-002808-84np9brx	326	38	,	,	,
cord-002808-84np9brx	326	39	L2	L2	NNP
cord-002808-84np9brx	326	40	,	,	,
cord-002808-84np9brx	326	41	at	at	IN
cord-002808-84np9brx	326	42	a	a	DT
cord-002808-84np9brx	326	43	furin	furin	NN
cord-002808-84np9brx	326	44	consensus	consensus	NN
cord-002808-84np9brx	326	45	site	site	NN
cord-002808-84np9brx	326	46	is	be	VBZ
cord-002808-84np9brx	326	47	necessary	necessary	JJ
cord-002808-84np9brx	326	48	for	for	IN
cord-002808-84np9brx	326	49	infection	infection	NN
cord-002808-84np9brx	326	50	Kallikrein-8	Kallikrein-8	NNP
cord-002808-84np9brx	327	1	proteolytically	proteolytically	NNP
cord-002808-84np9brx	327	2	processes	process	VBZ
cord-002808-84np9brx	327	3	human	human	JJ
cord-002808-84np9brx	327	4	papillomaviruses	papillomaviruse	NNS
cord-002808-84np9brx	327	5	in	in	IN
cord-002808-84np9brx	327	6	the	the	DT
cord-002808-84np9brx	327	7	extracellular	extracellular	JJ
cord-002808-84np9brx	327	8	space	space	NN
cord-002808-84np9brx	327	9	to	to	TO
cord-002808-84np9brx	327	10	facilitate	facilitate	VB
cord-002808-84np9brx	327	11	entry	entry	NN
cord-002808-84np9brx	327	12	into	into	IN
cord-002808-84np9brx	327	13	host	host	NN
cord-002808-84np9brx	327	14	cells	cell	NNS
cord-002808-84np9brx	327	15	Identification	identification	NN
cord-002808-84np9brx	327	16	of	of	IN
cord-002808-84np9brx	327	17	a	a	DT
cord-002808-84np9brx	327	18	role	role	NN
cord-002808-84np9brx	327	19	for	for	IN
cord-002808-84np9brx	327	20	the	the	DT
cord-002808-84np9brx	327	21	trans	trans	NNP
cord-002808-84np9brx	327	22	-	-	NNP
cord-002808-84np9brx	327	23	Golgi	Golgi	NNP
cord-002808-84np9brx	327	24	network	network	NN
cord-002808-84np9brx	327	25	in	in	IN
cord-002808-84np9brx	327	26	human	human	JJ
cord-002808-84np9brx	327	27	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	327	28	16	16	CD
cord-002808-84np9brx	327	29	pseudovirus	pseudovirus	JJ
cord-002808-84np9brx	327	30	infection	infection	NN
cord-002808-84np9brx	327	31	Entry	Entry	NNP
cord-002808-84np9brx	327	32	of	of	IN
cord-002808-84np9brx	327	33	human	human	JJ
cord-002808-84np9brx	327	34	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	327	35	type	type	NN
cord-002808-84np9brx	327	36	16	16	CD
cord-002808-84np9brx	327	37	by	by	IN
cord-002808-84np9brx	327	38	actin	actin	NN
cord-002808-84np9brx	327	39	-	-	HYPH
cord-002808-84np9brx	327	40	dependent	dependent	JJ
cord-002808-84np9brx	327	41	,	,	,
cord-002808-84np9brx	327	42	clathrin	clathrin	NN
cord-002808-84np9brx	327	43	-	-	HYPH
cord-002808-84np9brx	327	44	and	and	CC
cord-002808-84np9brx	327	45	lipid	lipid	JJ
cord-002808-84np9brx	327	46	raft	raft	NN
cord-002808-84np9brx	327	47	-	-	HYPH
cord-002808-84np9brx	327	48	independent	independent	JJ
cord-002808-84np9brx	327	49	endocytosis	endocytosis	NN
cord-002808-84np9brx	327	50	HPV16	hpv16	NN
cord-002808-84np9brx	327	51	infection	infection	NN
cord-002808-84np9brx	327	52	of	of	IN
cord-002808-84np9brx	327	53	HaCaTs	hacat	NNS
cord-002808-84np9brx	328	1	is	be	VBZ
cord-002808-84np9brx	328	2	dependent	dependent	JJ
cord-002808-84np9brx	328	3	on	on	IN
cord-002808-84np9brx	328	4	β4	β4	NNP
cord-002808-84np9brx	328	5	integrin	integrin	NNP
cord-002808-84np9brx	328	6	,	,	,
cord-002808-84np9brx	328	7	and	and	CC
cord-002808-84np9brx	328	8	α6	α6	NNP
cord-002808-84np9brx	328	9	integrin	integrin	NN
cord-002808-84np9brx	328	10	processing	process	VBG
cord-002808-84np9brx	328	11	Annexin	Annexin	NNP
cord-002808-84np9brx	328	12	A2	A2	NNP
cord-002808-84np9brx	328	13	and	and	CC
cord-002808-84np9brx	328	14	S100A10	s100a10	NN
cord-002808-84np9brx	329	1	regulate	regulate	VB
cord-002808-84np9brx	329	2	human	human	JJ
cord-002808-84np9brx	329	3	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	329	4	type	type	NN
cord-002808-84np9brx	329	5	16	16	CD
cord-002808-84np9brx	329	6	entry	entry	NN
cord-002808-84np9brx	329	7	and	and	CC
cord-002808-84np9brx	329	8	intracellular	intracellular	JJ
cord-002808-84np9brx	329	9	trafficking	trafficking	NN
cord-002808-84np9brx	329	10	in	in	IN
cord-002808-84np9brx	329	11	human	human	JJ
cord-002808-84np9brx	329	12	keratinocytes	keratinocyte	NNS
cord-002808-84np9brx	330	1	Tetraspanin	Tetraspanin	NNP
cord-002808-84np9brx	330	2	CD151	CD151	NNP
cord-002808-84np9brx	330	3	mediates	mediate	VBZ
cord-002808-84np9brx	330	4	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	330	5	type	type	NN
cord-002808-84np9brx	330	6	16	16	CD
cord-002808-84np9brx	330	7	endocytosis	endocytosis	NN
cord-002808-84np9brx	330	8	Clathrin	Clathrin	NNP
cord-002808-84np9brx	330	9	-	-	HYPH
cord-002808-84np9brx	330	10	and	and	CC
cord-002808-84np9brx	330	11	caveolin	caveolin	JJ
cord-002808-84np9brx	330	12	-	-	HYPH
cord-002808-84np9brx	330	13	independent	independent	JJ
cord-002808-84np9brx	330	14	entry	entry	NN
cord-002808-84np9brx	330	15	of	of	IN
cord-002808-84np9brx	330	16	human	human	JJ
cord-002808-84np9brx	330	17	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	330	18	type	type	NN
cord-002808-84np9brx	330	19	16-Involvement	16-involvement	CD
cord-002808-84np9brx	330	20	of	of	IN
cord-002808-84np9brx	330	21	tetraspanin	tetraspanin	NN
cord-002808-84np9brx	330	22	-	-	HYPH
cord-002808-84np9brx	330	23	enriched	enrich	VBN
cord-002808-84np9brx	330	24	microdomains	microdomain	NNS
cord-002808-84np9brx	330	25	(	(	-LRB-
cord-002808-84np9brx	330	26	tems	tem	NNS
cord-002808-84np9brx	330	27	)	)	-RRB-
cord-002808-84np9brx	330	28	Human	human	JJ
cord-002808-84np9brx	330	29	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	330	30	types	type	NNS
cord-002808-84np9brx	330	31	16	16	CD
cord-002808-84np9brx	330	32	,	,	,
cord-002808-84np9brx	330	33	18	18	CD
cord-002808-84np9brx	330	34	,	,	,
cord-002808-84np9brx	330	35	and	and	CC
cord-002808-84np9brx	330	36	31	31	CD
cord-002808-84np9brx	330	37	share	share	NN
cord-002808-84np9brx	330	38	similar	similar	JJ
cord-002808-84np9brx	330	39	endocytic	endocytic	JJ
cord-002808-84np9brx	330	40	requirements	requirement	NNS
cord-002808-84np9brx	330	41	for	for	IN
cord-002808-84np9brx	330	42	entry	entry	NN
cord-002808-84np9brx	330	43	Essential	essential	JJ
cord-002808-84np9brx	330	44	roles	role	NNS
cord-002808-84np9brx	330	45	for	for	IN
cord-002808-84np9brx	330	46	soluble	soluble	JJ
cord-002808-84np9brx	330	47	virion	virion	NN
cord-002808-84np9brx	330	48	-	-	HYPH
cord-002808-84np9brx	330	49	associated	associate	VBN
cord-002808-84np9brx	330	50	heparan	heparan	NN
cord-002808-84np9brx	330	51	sulfonated	sulfonate	VBN
cord-002808-84np9brx	330	52	proteoglycans	proteoglycan	NNS
cord-002808-84np9brx	330	53	and	and	CC
cord-002808-84np9brx	330	54	growth	growth	NN
cord-002808-84np9brx	330	55	factors	factor	NNS
cord-002808-84np9brx	330	56	in	in	IN
cord-002808-84np9brx	330	57	human	human	JJ
cord-002808-84np9brx	330	58	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	330	59	infections	infection	NNS
cord-002808-84np9brx	331	1	The	the	DT
cord-002808-84np9brx	331	2	S100A10	s100a10	NN
cord-002808-84np9brx	331	3	subunit	subunit	NN
cord-002808-84np9brx	331	4	of	of	IN
cord-002808-84np9brx	331	5	the	the	DT
cord-002808-84np9brx	331	6	annexin	annexin	NNP
cord-002808-84np9brx	331	7	A2	A2	NNP
cord-002808-84np9brx	331	8	heterotetramer	heterotetramer	NNP
cord-002808-84np9brx	331	9	facilitates	facilitate	VBZ
cord-002808-84np9brx	331	10	L2-mediated	l2-mediate	VBN
cord-002808-84np9brx	331	11	human	human	JJ
cord-002808-84np9brx	331	12	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	331	13	infection	infection	NN
cord-002808-84np9brx	332	1	The	the	DT
cord-002808-84np9brx	332	2	cytoskeletal	cytoskeletal	JJ
cord-002808-84np9brx	332	3	adaptor	adaptor	NN
cord-002808-84np9brx	332	4	obscurin	obscurin	NN
cord-002808-84np9brx	332	5	-	-	HYPH
cord-002808-84np9brx	332	6	like	like	JJ
cord-002808-84np9brx	332	7	1	1	CD
cord-002808-84np9brx	332	8	interacts	interact	VBZ
cord-002808-84np9brx	332	9	with	with	IN
cord-002808-84np9brx	332	10	the	the	DT
cord-002808-84np9brx	332	11	human	human	JJ
cord-002808-84np9brx	332	12	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	332	13	16	16	CD
cord-002808-84np9brx	332	14	(	(	-LRB-
cord-002808-84np9brx	332	15	HPV16	hpv16	NN
cord-002808-84np9brx	332	16	)	)	-RRB-
cord-002808-84np9brx	333	1	capsid	capsid	NNP
cord-002808-84np9brx	333	2	protein	protein	NN
cord-002808-84np9brx	333	3	L2	L2	NNP
cord-002808-84np9brx	333	4	and	and	CC
cord-002808-84np9brx	333	5	is	be	VBZ
cord-002808-84np9brx	333	6	required	require	VBN
cord-002808-84np9brx	333	7	for	for	IN
cord-002808-84np9brx	333	8	HPV16	hpv16	ADD
cord-002808-84np9brx	333	9	endocytosis	endocytosis	NN
cord-002808-84np9brx	334	1	The	the	DT
cord-002808-84np9brx	334	2	tetraspanin	tetraspanin	NNP
cord-002808-84np9brx	334	3	CD9	CD9	NNP
cord-002808-84np9brx	334	4	facilitates	facilitate	VBZ
cord-002808-84np9brx	334	5	mers	mers	NN
cord-002808-84np9brx	334	6	-	-	HYPH
cord-002808-84np9brx	334	7	coronavirus	coronavirus	NN
cord-002808-84np9brx	334	8	entry	entry	NN
cord-002808-84np9brx	334	9	by	by	IN
cord-002808-84np9brx	334	10	scaffolding	scaffold	VBG
cord-002808-84np9brx	334	11	host	host	NN
cord-002808-84np9brx	334	12	cell	cell	NN
cord-002808-84np9brx	334	13	receptors	receptor	NNS
cord-002808-84np9brx	334	14	and	and	CC
cord-002808-84np9brx	334	15	proteases	protease	NNS
cord-002808-84np9brx	334	16	CD81	CD81	NNP
cord-002808-84np9brx	334	17	and	and	CC
cord-002808-84np9brx	334	18	hepatitis	hepatitis	NN
cord-002808-84np9brx	334	19	c	c	NN
cord-002808-84np9brx	334	20	virus	virus	NN
cord-002808-84np9brx	334	21	(	(	-LRB-
cord-002808-84np9brx	334	22	HCV	HCV	NNP
cord-002808-84np9brx	334	23	)	)	-RRB-
cord-002808-84np9brx	334	24	infection	infection	NN
cord-002808-84np9brx	334	25	.	.	.
cord-002808-84np9brx	335	1	Viruses	virus	NNS
cord-002808-84np9brx	336	1	The	the	DT
cord-002808-84np9brx	336	2	role	role	NN
cord-002808-84np9brx	336	3	of	of	IN
cord-002808-84np9brx	336	4	furin	furin	NN
cord-002808-84np9brx	336	5	in	in	IN
cord-002808-84np9brx	336	6	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	336	7	infection	infection	NN
cord-002808-84np9brx	336	8	Furin	Furin	NNP
cord-002808-84np9brx	336	9	cleavage	cleavage	NN
cord-002808-84np9brx	336	10	of	of	IN
cord-002808-84np9brx	336	11	L2	l2	NN
cord-002808-84np9brx	336	12	during	during	IN
cord-002808-84np9brx	336	13	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	336	14	infection	infection	NN
cord-002808-84np9brx	336	15	:	:	:
cord-002808-84np9brx	336	16	Minimal	minimal	JJ
cord-002808-84np9brx	336	17	dependence	dependence	NN
cord-002808-84np9brx	336	18	on	on	IN
cord-002808-84np9brx	336	19	cyclophilins	cyclophilins	NNP
cord-002808-84np9brx	336	20	A	A	NNP
cord-002808-84np9brx	336	21	protective	protective	JJ
cord-002808-84np9brx	336	22	and	and	CC
cord-002808-84np9brx	336	23	broadly	broadly	RB
cord-002808-84np9brx	336	24	cross	cross	VB
cord-002808-84np9brx	336	25	-	-	JJ
cord-002808-84np9brx	336	26	neutralizing	neutralize	VBG
cord-002808-84np9brx	336	27	epitope	epitope	NN
cord-002808-84np9brx	336	28	of	of	IN
cord-002808-84np9brx	336	29	human	human	JJ
cord-002808-84np9brx	336	30	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	336	31	L2	L2	NNP
cord-002808-84np9brx	336	32	Mechanisms	Mechanisms	NNPS
cord-002808-84np9brx	336	33	of	of	IN
cord-002808-84np9brx	336	34	human	human	JJ
cord-002808-84np9brx	336	35	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	336	36	type	type	NN
cord-002808-84np9brx	336	37	16	16	CD
cord-002808-84np9brx	336	38	neutralization	neutralization	NN
cord-002808-84np9brx	336	39	by	by	IN
cord-002808-84np9brx	336	40	L2	L2	NNP
cord-002808-84np9brx	336	41	cross	cross	NN
cord-002808-84np9brx	336	42	-	-	JJ
cord-002808-84np9brx	336	43	neutralizing	neutralize	VBG
cord-002808-84np9brx	336	44	and	and	CC
cord-002808-84np9brx	336	45	L1	L1	NNP
cord-002808-84np9brx	336	46	type	type	NN
cord-002808-84np9brx	336	47	-	-	HYPH
cord-002808-84np9brx	336	48	specific	specific	JJ
cord-002808-84np9brx	336	49	antibodies	antibody	NNS
cord-002808-84np9brx	336	50	Target	Target	NNP
cord-002808-84np9brx	336	51	cell	cell	NN
cord-002808-84np9brx	336	52	cyclophilins	cyclophilin	NNS
cord-002808-84np9brx	336	53	facilitate	facilitate	VBP
cord-002808-84np9brx	336	54	human	human	JJ
cord-002808-84np9brx	336	55	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	336	56	type	type	NN
cord-002808-84np9brx	336	57	16	16	CD
cord-002808-84np9brx	336	58	infection	infection	NN
cord-002808-84np9brx	337	1	The	the	DT
cord-002808-84np9brx	337	2	CD63-syntenin-1	CD63-syntenin-1	NNP
cord-002808-84np9brx	337	3	complex	complex	JJ
cord-002808-84np9brx	337	4	controls	control	NNS
cord-002808-84np9brx	338	1	post	post	JJ
cord-002808-84np9brx	338	2	-	-	JJ
cord-002808-84np9brx	338	3	endocytic	endocytic	JJ
cord-002808-84np9brx	338	4	trafficking	trafficking	NN
cord-002808-84np9brx	338	5	of	of	IN
cord-002808-84np9brx	338	6	oncogenic	oncogenic	JJ
cord-002808-84np9brx	338	7	human	human	JJ
cord-002808-84np9brx	338	8	papillomaviruses	papillomaviruse	NNS
cord-002808-84np9brx	338	9	Human	human	JJ
cord-002808-84np9brx	338	10	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	338	11	infection	infection	NN
cord-002808-84np9brx	338	12	requires	require	VBZ
cord-002808-84np9brx	338	13	the	the	DT
cord-002808-84np9brx	338	14	TSG101	TSG101	NNP
cord-002808-84np9brx	338	15	component	component	NN
cord-002808-84np9brx	338	16	of	of	IN
cord-002808-84np9brx	338	17	the	the	DT
cord-002808-84np9brx	338	18	ESCRT	ESCRT	NNP
cord-002808-84np9brx	338	19	machinery	machinery	NN
cord-002808-84np9brx	339	1	The	the	DT
cord-002808-84np9brx	339	2	VPS4	VPS4	NNP
cord-002808-84np9brx	339	3	component	component	NN
cord-002808-84np9brx	339	4	of	of	IN
cord-002808-84np9brx	339	5	the	the	DT
cord-002808-84np9brx	339	6	ESCRT	ESCRT	NNP
cord-002808-84np9brx	339	7	machinery	machinery	NN
cord-002808-84np9brx	339	8	plays	play	VBZ
cord-002808-84np9brx	339	9	an	an	DT
cord-002808-84np9brx	339	10	essential	essential	JJ
cord-002808-84np9brx	339	11	role	role	NN
cord-002808-84np9brx	339	12	in	in	IN
cord-002808-84np9brx	339	13	hpv	hpv	NN
cord-002808-84np9brx	339	14	infectious	infectious	JJ
cord-002808-84np9brx	339	15	entry	entry	NN
cord-002808-84np9brx	339	16	and	and	CC
cord-002808-84np9brx	339	17	capsid	capsid	NN
cord-002808-84np9brx	339	18	disassembly	disassembly	NN
cord-002808-84np9brx	339	19	Inhibition	inhibition	NN
cord-002808-84np9brx	339	20	by	by	IN
cord-002808-84np9brx	339	21	cellular	cellular	JJ
cord-002808-84np9brx	339	22	vacuolar	vacuolar	NN
cord-002808-84np9brx	340	1	ATPase	ATPase	NNP
cord-002808-84np9brx	340	2	impairs	impair	VBZ
cord-002808-84np9brx	340	3	human	human	JJ
cord-002808-84np9brx	340	4	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	340	5	uncoating	uncoating	NN
cord-002808-84np9brx	340	6	and	and	CC
cord-002808-84np9brx	340	7	infection	infection	NN
cord-002808-84np9brx	340	8	Caveolin-1-dependent	caveolin-1-dependent	VBP
cord-002808-84np9brx	340	9	infectious	infectious	JJ
cord-002808-84np9brx	340	10	entry	entry	NN
cord-002808-84np9brx	340	11	of	of	IN
cord-002808-84np9brx	340	12	human	human	JJ
cord-002808-84np9brx	340	13	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	340	14	type	type	NN
cord-002808-84np9brx	340	15	31	31	CD
cord-002808-84np9brx	340	16	in	in	IN
cord-002808-84np9brx	340	17	human	human	JJ
cord-002808-84np9brx	340	18	keratinocytes	keratinocyte	NNS
cord-002808-84np9brx	340	19	proceeds	proceed	VBZ
cord-002808-84np9brx	340	20	to	to	IN
cord-002808-84np9brx	340	21	the	the	DT
cord-002808-84np9brx	340	22	endosomal	endosomal	NNP
cord-002808-84np9brx	340	23	pathway	pathway	NN
cord-002808-84np9brx	340	24	for	for	IN
cord-002808-84np9brx	340	25	pH	ph	NN
cord-002808-84np9brx	340	26	-	-	HYPH
cord-002808-84np9brx	340	27	dependent	dependent	JJ
cord-002808-84np9brx	340	28	uncoating	uncoate	VBG
cord-002808-84np9brx	340	29	Analysis	Analysis	NNP
cord-002808-84np9brx	340	30	of	of	IN
cord-002808-84np9brx	340	31	type	type	NN
cord-002808-84np9brx	340	32	-	-	HYPH
cord-002808-84np9brx	340	33	restricted	restrict	VBN
cord-002808-84np9brx	340	34	and	and	CC
cord-002808-84np9brx	340	35	cross	cross	JJ
cord-002808-84np9brx	340	36	-	-	JJ
cord-002808-84np9brx	340	37	reactive	reactive	JJ
cord-002808-84np9brx	340	38	epitopes	epitope	NNS
cord-002808-84np9brx	340	39	on	on	IN
cord-002808-84np9brx	340	40	virus	virus	NN
cord-002808-84np9brx	340	41	-	-	HYPH
cord-002808-84np9brx	340	42	like	like	JJ
cord-002808-84np9brx	340	43	particles	particle	NNS
cord-002808-84np9brx	340	44	of	of	IN
cord-002808-84np9brx	340	45	human	human	JJ
cord-002808-84np9brx	340	46	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	340	47	type	type	NN
cord-002808-84np9brx	340	48	33	33	CD
cord-002808-84np9brx	340	49	and	and	CC
cord-002808-84np9brx	340	50	in	in	IN
cord-002808-84np9brx	340	51	infected	infected	JJ
cord-002808-84np9brx	340	52	tissues	tissue	NNS
cord-002808-84np9brx	340	53	using	use	VBG
cord-002808-84np9brx	340	54	monoclonal	monoclonal	JJ
cord-002808-84np9brx	340	55	antibodies	antibody	NNS
cord-002808-84np9brx	340	56	to	to	IN
cord-002808-84np9brx	340	57	the	the	DT
cord-002808-84np9brx	340	58	major	major	JJ
cord-002808-84np9brx	340	59	capsid	capsid	NN
cord-002808-84np9brx	340	60	protein	protein	NN
cord-002808-84np9brx	340	61	Cyclophilins	Cyclophilins	NNP
cord-002808-84np9brx	340	62	facilitate	facilitate	VBP
cord-002808-84np9brx	340	63	dissociation	dissociation	NN
cord-002808-84np9brx	340	64	of	of	IN
cord-002808-84np9brx	340	65	the	the	DT
cord-002808-84np9brx	340	66	human	human	JJ
cord-002808-84np9brx	340	67	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	340	68	type	type	NN
cord-002808-84np9brx	340	69	16	16	CD
cord-002808-84np9brx	340	70	capsid	capsid	NN
cord-002808-84np9brx	340	71	protein	protein	NN
cord-002808-84np9brx	340	72	L1	L1	NNP
cord-002808-84np9brx	340	73	from	from	IN
cord-002808-84np9brx	340	74	the	the	DT
cord-002808-84np9brx	340	75	L2	L2	NNP
cord-002808-84np9brx	340	76	/	/	SYM
cord-002808-84np9brx	340	77	DNA	dna	NN
cord-002808-84np9brx	340	78	complex	complex	JJ
cord-002808-84np9brx	340	79	following	follow	VBG
cord-002808-84np9brx	340	80	virus	virus	NN
cord-002808-84np9brx	340	81	entry	entry	NN
cord-002808-84np9brx	340	82	Genome	Genome	NNP
cord-002808-84np9brx	340	83	-	-	HYPH
cord-002808-84np9brx	340	84	wide	wide	JJ
cord-002808-84np9brx	340	85	siRNA	siRNA	NNP
cord-002808-84np9brx	340	86	screen	screen	NN
cord-002808-84np9brx	340	87	identifies	identify	VBZ
cord-002808-84np9brx	340	88	the	the	DT
cord-002808-84np9brx	340	89	retromer	retromer	NN
cord-002808-84np9brx	340	90	as	as	IN
cord-002808-84np9brx	340	91	a	a	DT
cord-002808-84np9brx	340	92	cellular	cellular	JJ
cord-002808-84np9brx	340	93	entry	entry	NN
cord-002808-84np9brx	340	94	factor	factor	NN
cord-002808-84np9brx	340	95	for	for	IN
cord-002808-84np9brx	340	96	human	human	JJ
cord-002808-84np9brx	340	97	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	340	98	Direct	direct	JJ
cord-002808-84np9brx	340	99	binding	binding	NN
cord-002808-84np9brx	340	100	of	of	IN
cord-002808-84np9brx	340	101	retromer	retromer	NN
cord-002808-84np9brx	340	102	to	to	IN
cord-002808-84np9brx	340	103	human	human	JJ
cord-002808-84np9brx	340	104	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	340	105	type	type	NN
cord-002808-84np9brx	341	1	16	16	CD
cord-002808-84np9brx	341	2	minor	minor	JJ
cord-002808-84np9brx	341	3	capsid	capsid	NN
cord-002808-84np9brx	341	4	protein	protein	NN
cord-002808-84np9brx	341	5	L2	L2	NNP
cord-002808-84np9brx	341	6	mediates	mediate	VBZ
cord-002808-84np9brx	341	7	endosome	endosome	NN
cord-002808-84np9brx	341	8	exit	exit	NN
cord-002808-84np9brx	341	9	during	during	IN
cord-002808-84np9brx	341	10	viral	viral	JJ
cord-002808-84np9brx	341	11	infection	infection	NN
cord-002808-84np9brx	342	1	A	a	DT
cord-002808-84np9brx	342	2	central	central	JJ
cord-002808-84np9brx	342	3	region	region	NN
cord-002808-84np9brx	342	4	in	in	IN
cord-002808-84np9brx	342	5	the	the	DT
cord-002808-84np9brx	342	6	minor	minor	JJ
cord-002808-84np9brx	342	7	capsid	capsid	NN
cord-002808-84np9brx	342	8	protein	protein	NN
cord-002808-84np9brx	342	9	of	of	IN
cord-002808-84np9brx	342	10	papillomaviruses	papillomaviruse	NNS
cord-002808-84np9brx	342	11	facilitates	facilitate	VBZ
cord-002808-84np9brx	342	12	viral	viral	JJ
cord-002808-84np9brx	342	13	genome	genome	NN
cord-002808-84np9brx	342	14	tethering	tethering	NN
cord-002808-84np9brx	342	15	and	and	CC
cord-002808-84np9brx	342	16	membrane	membrane	NN
cord-002808-84np9brx	342	17	penetration	penetration	NN
cord-002808-84np9brx	342	18	for	for	IN
cord-002808-84np9brx	342	19	mitotic	mitotic	JJ
cord-002808-84np9brx	342	20	nuclear	nuclear	JJ
cord-002808-84np9brx	342	21	entry	entry	NN
cord-002808-84np9brx	343	1	Large	large	JJ
cord-002808-84np9brx	343	2	scale	scale	NN
cord-002808-84np9brx	343	3	RNAi	RNAi	NNS
cord-002808-84np9brx	343	4	reveals	reveal	VBZ
cord-002808-84np9brx	343	5	the	the	DT
cord-002808-84np9brx	343	6	requirement	requirement	NN
cord-002808-84np9brx	343	7	of	of	IN
cord-002808-84np9brx	343	8	nuclear	nuclear	JJ
cord-002808-84np9brx	343	9	envelope	envelope	NN
cord-002808-84np9brx	343	10	breakdown	breakdown	NN
cord-002808-84np9brx	343	11	for	for	IN
cord-002808-84np9brx	343	12	nuclear	nuclear	JJ
cord-002808-84np9brx	343	13	import	import	NN
cord-002808-84np9brx	343	14	of	of	IN
cord-002808-84np9brx	343	15	human	human	JJ
cord-002808-84np9brx	343	16	papillomaviruses	papillomaviruse	NNS
cord-002808-84np9brx	343	17	Translocation	Translocation	NNP
cord-002808-84np9brx	343	18	of	of	IN
cord-002808-84np9brx	343	19	the	the	DT
cord-002808-84np9brx	343	20	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	343	21	L2	L2	NNP
cord-002808-84np9brx	343	22	/	/	,
cord-002808-84np9brx	343	23	vDNA	vdna	RB
cord-002808-84np9brx	343	24	complex	complex	NN
cord-002808-84np9brx	343	25	across	across	IN
cord-002808-84np9brx	343	26	the	the	DT
cord-002808-84np9brx	343	27	limiting	limit	VBG
cord-002808-84np9brx	343	28	membrane	membrane	NN
cord-002808-84np9brx	343	29	requires	require	VBZ
cord-002808-84np9brx	343	30	the	the	DT
cord-002808-84np9brx	343	31	onset	onset	NN
cord-002808-84np9brx	343	32	of	of	IN
cord-002808-84np9brx	343	33	mitosis	mitosis	NN
cord-002808-84np9brx	343	34	Human	human	JJ
cord-002808-84np9brx	343	35	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	343	36	major	major	JJ
cord-002808-84np9brx	343	37	capsid	capsid	NN
cord-002808-84np9brx	343	38	protein	protein	NN
cord-002808-84np9brx	343	39	L1	L1	NNP
cord-002808-84np9brx	343	40	remains	remain	VBZ
cord-002808-84np9brx	343	41	associated	associate	VBN
cord-002808-84np9brx	343	42	with	with	IN
cord-002808-84np9brx	343	43	the	the	DT
cord-002808-84np9brx	343	44	incoming	incoming	JJ
cord-002808-84np9brx	343	45	viral	viral	JJ
cord-002808-84np9brx	343	46	genome	genome	NN
cord-002808-84np9brx	343	47	throughout	throughout	IN
cord-002808-84np9brx	343	48	the	the	DT
cord-002808-84np9brx	343	49	entry	entry	NN
cord-002808-84np9brx	343	50	process	process	NN
cord-002808-84np9brx	343	51	Identification	identification	NN
cord-002808-84np9brx	343	52	of	of	IN
cord-002808-84np9brx	343	53	TrappC8	trappc8	NN
cord-002808-84np9brx	343	54	as	as	IN
cord-002808-84np9brx	343	55	a	a	DT
cord-002808-84np9brx	343	56	host	host	NN
cord-002808-84np9brx	343	57	factor	factor	NN
cord-002808-84np9brx	343	58	required	require	VBN
cord-002808-84np9brx	343	59	for	for	IN
cord-002808-84np9brx	343	60	human	human	JJ
cord-002808-84np9brx	343	61	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	343	62	cell	cell	NN
cord-002808-84np9brx	343	63	entry	entry	NN
cord-002808-84np9brx	343	64	Application	Application	NNP
cord-002808-84np9brx	343	65	of	of	IN
cord-002808-84np9brx	343	66	the	the	DT
cord-002808-84np9brx	343	67	proximity	proximity	NN
cord-002808-84np9brx	343	68	-	-	HYPH
cord-002808-84np9brx	343	69	dependent	dependent	JJ
cord-002808-84np9brx	343	70	assay	assay	NN
cord-002808-84np9brx	343	71	and	and	CC
cord-002808-84np9brx	343	72	fluorescence	fluorescence	NN
cord-002808-84np9brx	343	73	imaging	imaging	NN
cord-002808-84np9brx	343	74	approaches	approach	NNS
cord-002808-84np9brx	343	75	to	to	TO
cord-002808-84np9brx	343	76	study	study	VB
cord-002808-84np9brx	343	77	viral	viral	JJ
cord-002808-84np9brx	343	78	entry	entry	NN
cord-002808-84np9brx	343	79	pathways	pathway	NNS
cord-002808-84np9brx	344	1	Vesicular	vesicular	JJ
cord-002808-84np9brx	344	2	trafficking	trafficking	NN
cord-002808-84np9brx	344	3	of	of	IN
cord-002808-84np9brx	344	4	incoming	incoming	JJ
cord-002808-84np9brx	344	5	human	human	JJ
cord-002808-84np9brx	344	6	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	344	7	16	16	CD
cord-002808-84np9brx	344	8	to	to	IN
cord-002808-84np9brx	344	9	the	the	DT
cord-002808-84np9brx	344	10	Golgi	Golgi	NNP
cord-002808-84np9brx	344	11	apparatus	apparatus	NN
cord-002808-84np9brx	344	12	and	and	CC
cord-002808-84np9brx	344	13	endoplasmic	endoplasmic	NN
cord-002808-84np9brx	344	14	reticulum	reticulum	NN
cord-002808-84np9brx	344	15	requires	require	VBZ
cord-002808-84np9brx	344	16	γ	γ	NN
cord-002808-84np9brx	344	17	-	-	HYPH
cord-002808-84np9brx	344	18	secretase	secretase	NNP
cord-002808-84np9brx	344	19	activity	activity	NN
cord-002808-84np9brx	345	1	Protein	protein	NN
cord-002808-84np9brx	345	2	sorting	sort	VBG
cord-002808-84np9brx	345	3	at	at	IN
cord-002808-84np9brx	345	4	the	the	DT
cord-002808-84np9brx	345	5	ER	ER	NNP
cord-002808-84np9brx	345	6	-	-	HYPH
cord-002808-84np9brx	345	7	Golgi	Golgi	NNP
cord-002808-84np9brx	345	8	interface	interface	NN
cord-002808-84np9brx	345	9	Golgi	Golgi	NNP
cord-002808-84np9brx	345	10	enzymes	enzyme	NNS
cord-002808-84np9brx	345	11	do	do	VBP
cord-002808-84np9brx	345	12	not	not	RB
cord-002808-84np9brx	345	13	cycle	cycle	VB
cord-002808-84np9brx	345	14	through	through	IN
cord-002808-84np9brx	345	15	the	the	DT
cord-002808-84np9brx	345	16	endoplasmic	endoplasmic	NN
cord-002808-84np9brx	345	17	reticulum	reticulum	NN
cord-002808-84np9brx	345	18	during	during	IN
cord-002808-84np9brx	345	19	protein	protein	NN
cord-002808-84np9brx	345	20	secretion	secretion	NN
cord-002808-84np9brx	345	21	or	or	CC
cord-002808-84np9brx	345	22	mitosis	mitosis	NN
cord-002808-84np9brx	345	23	Retromer	Retromer	NNP
cord-002808-84np9brx	345	24	:	:	:
cord-002808-84np9brx	346	1	A	a	DT
cord-002808-84np9brx	346	2	master	master	NN
cord-002808-84np9brx	346	3	conductor	conductor	NN
cord-002808-84np9brx	346	4	of	of	IN
cord-002808-84np9brx	346	5	endosome	endosome	NN
cord-002808-84np9brx	346	6	sorting	sort	VBG
cord-002808-84np9brx	346	7	Human	human	JJ
cord-002808-84np9brx	346	8	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	346	9	L2	l2	NN
cord-002808-84np9brx	346	10	facilitates	facilitate	VBZ
cord-002808-84np9brx	346	11	viral	viral	JJ
cord-002808-84np9brx	346	12	escape	escape	NN
cord-002808-84np9brx	346	13	from	from	IN
cord-002808-84np9brx	346	14	late	late	JJ
cord-002808-84np9brx	346	15	endosomes	endosome	NNS
cord-002808-84np9brx	346	16	via	via	IN
cord-002808-84np9brx	346	17	sorting	sort	VBG
cord-002808-84np9brx	346	18	nexin	nexin	NN
cord-002808-84np9brx	346	19	17	17	CD
cord-002808-84np9brx	346	20	A	a	DT
cord-002808-84np9brx	346	21	novel	novel	NN
cord-002808-84np9brx	347	1	PDZ	PDZ	NNP
cord-002808-84np9brx	347	2	domain	domain	NN
cord-002808-84np9brx	347	3	interaction	interaction	NN
cord-002808-84np9brx	347	4	mediates	mediate	VBZ
cord-002808-84np9brx	347	5	the	the	DT
cord-002808-84np9brx	347	6	binding	binding	NN
cord-002808-84np9brx	347	7	between	between	IN
cord-002808-84np9brx	347	8	human	human	JJ
cord-002808-84np9brx	347	9	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	347	10	16	16	CD
cord-002808-84np9brx	347	11	L2	l2	NN
cord-002808-84np9brx	347	12	and	and	CC
cord-002808-84np9brx	347	13	sorting	sort	VBG
cord-002808-84np9brx	347	14	nexin	nexin	NN
cord-002808-84np9brx	347	15	27	27	CD
cord-002808-84np9brx	347	16	and	and	CC
cord-002808-84np9brx	347	17	modulates	modulate	VBZ
cord-002808-84np9brx	347	18	virion	virion	NN
cord-002808-84np9brx	347	19	trafficking	traffic	VBG
cord-002808-84np9brx	347	20	Characterizing	characterize	VBG
cord-002808-84np9brx	347	21	the	the	DT
cord-002808-84np9brx	347	22	spatio	spatio	JJ
cord-002808-84np9brx	347	23	-	-	HYPH
cord-002808-84np9brx	347	24	temporal	temporal	JJ
cord-002808-84np9brx	347	25	role	role	NN
cord-002808-84np9brx	347	26	of	of	IN
cord-002808-84np9brx	347	27	sorting	sort	VBG
cord-002808-84np9brx	347	28	nexin	nexin	NN
cord-002808-84np9brx	347	29	17	17	CD
cord-002808-84np9brx	347	30	in	in	IN
cord-002808-84np9brx	347	31	human	human	JJ
cord-002808-84np9brx	347	32	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	347	33	trafficking	traffic	VBG
cord-002808-84np9brx	347	34	SNX17	SNX17	NNP
cord-002808-84np9brx	347	35	regulates	regulate	VBZ
cord-002808-84np9brx	347	36	notch	notch	JJ
cord-002808-84np9brx	347	37	pathway	pathway	NN
cord-002808-84np9brx	347	38	and	and	CC
cord-002808-84np9brx	347	39	pancreas	pancreas	NN
cord-002808-84np9brx	347	40	development	development	NN
cord-002808-84np9brx	347	41	through	through	IN
cord-002808-84np9brx	347	42	the	the	DT
cord-002808-84np9brx	347	43	retromer	retromer	NN
cord-002808-84np9brx	347	44	-	-	HYPH
cord-002808-84np9brx	347	45	dependent	dependent	JJ
cord-002808-84np9brx	347	46	recycling	recycling	NN
cord-002808-84np9brx	347	47	of	of	IN
cord-002808-84np9brx	347	48	jag1	jag1	NNP
cord-002808-84np9brx	347	49	Retriever	Retriever	NNP
cord-002808-84np9brx	347	50	is	be	VBZ
cord-002808-84np9brx	347	51	a	a	DT
cord-002808-84np9brx	347	52	multiprotein	multiprotein	NN
cord-002808-84np9brx	347	53	complex	complex	NN
cord-002808-84np9brx	347	54	for	for	IN
cord-002808-84np9brx	347	55	retromer	retromer	NN
cord-002808-84np9brx	347	56	-	-	HYPH
cord-002808-84np9brx	347	57	independent	independent	JJ
cord-002808-84np9brx	347	58	endosomal	endosomal	NNP
cord-002808-84np9brx	347	59	cargo	cargo	NN
cord-002808-84np9brx	347	60	recycling	recycling	NN
cord-002808-84np9brx	347	61	Presenilins	Presenilins	NNP
cord-002808-84np9brx	347	62	and	and	CC
cord-002808-84np9brx	347	63	γ	γ	NN
cord-002808-84np9brx	347	64	-	-	HYPH
cord-002808-84np9brx	347	65	secretase	secretase	NNP
cord-002808-84np9brx	347	66	:	:	:
cord-002808-84np9brx	347	67	Structure	structure	NN
cord-002808-84np9brx	347	68	,	,	,
cord-002808-84np9brx	347	69	function	function	NN
cord-002808-84np9brx	347	70	,	,	,
cord-002808-84np9brx	347	71	and	and	CC
cord-002808-84np9brx	347	72	role	role	NN
cord-002808-84np9brx	347	73	in	in	IN
cord-002808-84np9brx	347	74	alzheimer	alzheimer	NNP
cord-002808-84np9brx	347	75	disease	disease	NNP
cord-002808-84np9brx	347	76	.	.	.
cord-002808-84np9brx	348	1	Cold	Cold	NNP
cord-002808-84np9brx	348	2	Spring	Spring	NNP
cord-002808-84np9brx	348	3	Harb	Harb	NNP
cord-002808-84np9brx	348	4	Substrate	Substrate	NNP
cord-002808-84np9brx	348	5	specificity	specificity	NN
cord-002808-84np9brx	348	6	of	of	IN
cord-002808-84np9brx	348	7	γ	γ	NN
cord-002808-84np9brx	348	8	-	-	HYPH
cord-002808-84np9brx	348	9	secretase	secretase	NNP
cord-002808-84np9brx	348	10	and	and	CC
cord-002808-84np9brx	348	11	other	other	JJ
cord-002808-84np9brx	348	12	intramembrane	intramembrane	NNP
cord-002808-84np9brx	348	13	proteases	protease	NNS
cord-002808-84np9brx	349	1	A	a	DT
cord-002808-84np9brx	349	2	greek	greek	JJ
cord-002808-84np9brx	349	3	tragedy	tragedy	NN
cord-002808-84np9brx	349	4	:	:	:
cord-002808-84np9brx	350	1	The	the	DT
cord-002808-84np9brx	350	2	growing	grow	VBG
cord-002808-84np9brx	350	3	complexity	complexity	NN
cord-002808-84np9brx	350	4	of	of	IN
cord-002808-84np9brx	350	5	alzheimer	alzheimer	NNP
cord-002808-84np9brx	350	6	amyloid	amyloid	NNP
cord-002808-84np9brx	350	7	precursor	precursor	NN
cord-002808-84np9brx	350	8	protein	protein	NN
cord-002808-84np9brx	350	9	proteolysis	proteolysis	NNP
cord-002808-84np9brx	351	1	A	a	DT
cord-002808-84np9brx	352	1	presenilin-1-dependent	presenilin-1-dependent	NNP
cord-002808-84np9brx	352	2	gamma	gamma	NN
cord-002808-84np9brx	352	3	-	-	HYPH
cord-002808-84np9brx	352	4	secretase	secretase	JJ
cord-002808-84np9brx	352	5	-	-	HYPH
cord-002808-84np9brx	352	6	like	like	JJ
cord-002808-84np9brx	352	7	protease	protease	NN
cord-002808-84np9brx	352	8	mediates	mediate	VBZ
cord-002808-84np9brx	352	9	release	release	NN
cord-002808-84np9brx	352	10	of	of	IN
cord-002808-84np9brx	352	11	notch	notch	NN
cord-002808-84np9brx	352	12	intracellular	intracellular	JJ
cord-002808-84np9brx	352	13	domain	domain	NN
cord-002808-84np9brx	352	14	Total	total	JJ
cord-002808-84np9brx	352	15	inactivation	inactivation	NN
cord-002808-84np9brx	352	16	of	of	IN
cord-002808-84np9brx	352	17	gamma	gamma	NN
cord-002808-84np9brx	352	18	-	-	HYPH
cord-002808-84np9brx	352	19	secretase	secretase	JJ
cord-002808-84np9brx	352	20	activity	activity	NN
cord-002808-84np9brx	352	21	in	in	IN
cord-002808-84np9brx	352	22	presenilin	presenilin	NN
cord-002808-84np9brx	352	23	-	-	HYPH
cord-002808-84np9brx	352	24	deficient	deficient	JJ
cord-002808-84np9brx	352	25	embryonic	embryonic	JJ
cord-002808-84np9brx	352	26	stem	stem	NN
cord-002808-84np9brx	352	27	cells	cell	NNS
cord-002808-84np9brx	353	1	Presenilins	presenilin	NNS
cord-002808-84np9brx	353	2	are	be	VBP
cord-002808-84np9brx	353	3	required	require	VBN
cord-002808-84np9brx	353	4	for	for	IN
cord-002808-84np9brx	353	5	γ	γ	NN
cord-002808-84np9brx	353	6	-	-	HYPH
cord-002808-84np9brx	353	7	secretase	secretase	NNP
cord-002808-84np9brx	353	8	cleavage	cleavage	NN
cord-002808-84np9brx	353	9	of	of	IN
cord-002808-84np9brx	353	10	β	β	NN
cord-002808-84np9brx	353	11	-	-	HYPH
cord-002808-84np9brx	353	12	APP	app	NN
cord-002808-84np9brx	353	13	and	and	CC
cord-002808-84np9brx	353	14	transmembrane	transmembrane	NN
cord-002808-84np9brx	353	15	cleavage	cleavage	NN
cord-002808-84np9brx	353	16	of	of	IN
cord-002808-84np9brx	353	17	Notch-1	Notch-1	NNP
cord-002808-84np9brx	353	18	Papillomavirus	Papillomavirus	NNP
cord-002808-84np9brx	353	19	infection	infection	NN
cord-002808-84np9brx	353	20	requires	require	VBZ
cord-002808-84np9brx	353	21	gamma	gamma	NN
cord-002808-84np9brx	353	22	secretase	secretase	NNP
cord-002808-84np9brx	353	23	Impact	Impact	NNP
cord-002808-84np9brx	353	24	of	of	IN
cord-002808-84np9brx	353	25	inhibitors	inhibitor	NNS
cord-002808-84np9brx	353	26	and	and	CC
cord-002808-84np9brx	353	27	L2	L2	NNP
cord-002808-84np9brx	353	28	antibodies	antibody	NNS
cord-002808-84np9brx	353	29	upon	upon	IN
cord-002808-84np9brx	353	30	the	the	DT
cord-002808-84np9brx	353	31	infectivity	infectivity	NN
cord-002808-84np9brx	353	32	of	of	IN
cord-002808-84np9brx	353	33	diverse	diverse	JJ
cord-002808-84np9brx	353	34	alpha	alpha	NN
cord-002808-84np9brx	353	35	and	and	CC
cord-002808-84np9brx	353	36	beta	beta	JJ
cord-002808-84np9brx	353	37	human	human	JJ
cord-002808-84np9brx	353	38	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	353	39	types	type	NNS
cord-002808-84np9brx	353	40	Beyond	beyond	IN
cord-002808-84np9brx	353	41	γ	γ	NN
cord-002808-84np9brx	353	42	-	-	HYPH
cord-002808-84np9brx	353	43	secretase	secretase	NNP
cord-002808-84np9brx	353	44	activity	activity	NN
cord-002808-84np9brx	353	45	:	:	:
cord-002808-84np9brx	353	46	The	the	DT
cord-002808-84np9brx	353	47	multifunctional	multifunctional	JJ
cord-002808-84np9brx	353	48	nature	nature	NN
cord-002808-84np9brx	353	49	of	of	IN
cord-002808-84np9brx	353	50	presenilins	presenilin	NNS
cord-002808-84np9brx	353	51	in	in	IN
cord-002808-84np9brx	353	52	cell	cell	NN
cord-002808-84np9brx	353	53	signalling	signal	VBG
cord-002808-84np9brx	353	54	pathways	pathway	NNS
cord-002808-84np9brx	353	55	Amyloid	Amyloid	NNP
cord-002808-84np9brx	353	56	precursor	precursor	NN
cord-002808-84np9brx	353	57	protein	protein	NN
cord-002808-84np9brx	353	58	(	(	-LRB-
cord-002808-84np9brx	353	59	APP	app	NN
cord-002808-84np9brx	353	60	)	)	-RRB-
cord-002808-84np9brx	353	61	traffics	traffic	VBZ
cord-002808-84np9brx	353	62	from	from	IN
cord-002808-84np9brx	353	63	the	the	DT
cord-002808-84np9brx	353	64	cell	cell	NN
cord-002808-84np9brx	353	65	surface	surface	NN
cord-002808-84np9brx	353	66	via	via	IN
cord-002808-84np9brx	353	67	endosomes	endosome	NNS
cord-002808-84np9brx	353	68	for	for	IN
cord-002808-84np9brx	353	69	amyloid	amyloid	NN
cord-002808-84np9brx	353	70	β	β	NNP
cord-002808-84np9brx	353	71	(	(	-LRB-
cord-002808-84np9brx	353	72	Aβ	aβ	NN
cord-002808-84np9brx	353	73	)	)	-RRB-
cord-002808-84np9brx	353	74	production	production	NN
cord-002808-84np9brx	353	75	in	in	IN
cord-002808-84np9brx	353	76	the	the	DT
cord-002808-84np9brx	353	77	trans	trans	NNP
cord-002808-84np9brx	353	78	-	-	NNP
cord-002808-84np9brx	353	79	Golgi	Golgi	NNP
cord-002808-84np9brx	353	80	network	network	NN
cord-002808-84np9brx	353	81	Sorting	sort	VBG
cord-002808-84np9brx	353	82	through	through	IN
cord-002808-84np9brx	353	83	the	the	DT
cord-002808-84np9brx	353	84	cell	cell	NN
cord-002808-84np9brx	353	85	biology	biology	NN
cord-002808-84np9brx	353	86	of	of	IN
cord-002808-84np9brx	353	87	alzheimer	alzheimer	NNP
cord-002808-84np9brx	353	88	's	's	POS
cord-002808-84np9brx	353	89	disease	disease	NN
cord-002808-84np9brx	353	90	:	:	:
cord-002808-84np9brx	354	1	Intracellular	Intracellular	NNP
cord-002808-84np9brx	354	2	pathways	pathway	NNS
cord-002808-84np9brx	354	3	to	to	TO
cord-002808-84np9brx	354	4	pathogenesis	pathogenesis	VB
cord-002808-84np9brx	354	5	Expression	expression	NN
cord-002808-84np9brx	354	6	of	of	IN
cord-002808-84np9brx	354	7	the	the	DT
cord-002808-84np9brx	354	8	L2	L2	NNP
cord-002808-84np9brx	354	9	and	and	CC
cord-002808-84np9brx	354	10	E7	E7	NNP
cord-002808-84np9brx	354	11	genes	gene	NNS
cord-002808-84np9brx	354	12	of	of	IN
cord-002808-84np9brx	354	13	the	the	DT
cord-002808-84np9brx	354	14	human	human	JJ
cord-002808-84np9brx	354	15	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	354	16	type	type	NN
cord-002808-84np9brx	354	17	16	16	CD
cord-002808-84np9brx	354	18	in	in	IN
cord-002808-84np9brx	354	19	female	female	JJ
cord-002808-84np9brx	354	20	genital	genital	JJ
cord-002808-84np9brx	354	21	dysplasias	dysplasias	NNP
cord-002808-84np9brx	354	22	Self	self	NN
cord-002808-84np9brx	354	23	-	-	HYPH
cord-002808-84np9brx	354	24	assembly	assembly	NNP
cord-002808-84np9brx	354	25	of	of	IN
cord-002808-84np9brx	354	26	human	human	JJ
cord-002808-84np9brx	354	27	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	354	28	type	type	NN
cord-002808-84np9brx	354	29	1	1	CD
cord-002808-84np9brx	354	30	capsids	capsid	NNS
cord-002808-84np9brx	354	31	by	by	IN
cord-002808-84np9brx	354	32	expression	expression	NN
cord-002808-84np9brx	354	33	of	of	IN
cord-002808-84np9brx	354	34	the	the	DT
cord-002808-84np9brx	354	35	L1	L1	NNP
cord-002808-84np9brx	354	36	protein	protein	NN
cord-002808-84np9brx	354	37	alone	alone	RB
cord-002808-84np9brx	354	38	or	or	CC
cord-002808-84np9brx	354	39	by	by	IN
cord-002808-84np9brx	354	40	coexpression	coexpression	NN
cord-002808-84np9brx	354	41	of	of	IN
cord-002808-84np9brx	354	42	the	the	DT
cord-002808-84np9brx	354	43	L1	L1	NNP
cord-002808-84np9brx	354	44	and	and	CC
cord-002808-84np9brx	354	45	L2	L2	NNP
cord-002808-84np9brx	354	46	capsid	capsid	NN
cord-002808-84np9brx	354	47	proteins	protein	NNS
cord-002808-84np9brx	355	1	A	a	DT
cord-002808-84np9brx	355	2	membrane	membrane	NN
cord-002808-84np9brx	355	3	-	-	HYPH
cord-002808-84np9brx	355	4	destabilizing	destabilize	VBG
cord-002808-84np9brx	355	5	peptide	peptide	NN
cord-002808-84np9brx	355	6	in	in	IN
cord-002808-84np9brx	355	7	capsid	capsid	JJ
cord-002808-84np9brx	355	8	protein	protein	NN
cord-002808-84np9brx	355	9	L2	L2	NNP
cord-002808-84np9brx	355	10	is	be	VBZ
cord-002808-84np9brx	355	11	required	require	VBN
cord-002808-84np9brx	355	12	for	for	IN
cord-002808-84np9brx	355	13	egress	egress	NN
cord-002808-84np9brx	355	14	of	of	IN
cord-002808-84np9brx	355	15	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	355	16	genomes	genome	NNS
cord-002808-84np9brx	355	17	from	from	IN
cord-002808-84np9brx	355	18	endosomes	endosome	NNS
cord-002808-84np9brx	355	19	A	a	DT
cord-002808-84np9brx	355	20	transmembrane	transmembrane	NN
cord-002808-84np9brx	355	21	domain	domain	NN
cord-002808-84np9brx	355	22	and	and	CC
cord-002808-84np9brx	355	23	GxxxG	GxxxG	NNP
cord-002808-84np9brx	355	24	motifs	motif	NNS
cord-002808-84np9brx	355	25	within	within	IN
cord-002808-84np9brx	355	26	L2	L2	NNP
cord-002808-84np9brx	355	27	are	be	VBP
cord-002808-84np9brx	355	28	essential	essential	JJ
cord-002808-84np9brx	355	29	for	for	IN
cord-002808-84np9brx	355	30	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	355	31	infection	infection	NN
cord-002808-84np9brx	355	32	Topography	Topography	NNP
cord-002808-84np9brx	355	33	of	of	IN
cord-002808-84np9brx	355	34	the	the	DT
cord-002808-84np9brx	355	35	human	human	JJ
cord-002808-84np9brx	355	36	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	355	37	minor	minor	JJ
cord-002808-84np9brx	355	38	capsid	capsid	NN
cord-002808-84np9brx	355	39	protein	protein	NN
cord-002808-84np9brx	355	40	L2	l2	NN
cord-002808-84np9brx	355	41	during	during	IN
cord-002808-84np9brx	355	42	vesicular	vesicular	JJ
cord-002808-84np9brx	355	43	trafficking	trafficking	NN
cord-002808-84np9brx	355	44	of	of	IN
cord-002808-84np9brx	355	45	infectious	infectious	JJ
cord-002808-84np9brx	355	46	entry	entry	NN
cord-002808-84np9brx	356	1	Incoming	incoming	JJ
cord-002808-84np9brx	356	2	human	human	JJ
cord-002808-84np9brx	356	3	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	356	4	type	type	NN
cord-002808-84np9brx	356	5	16	16	CD
cord-002808-84np9brx	356	6	genome	genome	NN
cord-002808-84np9brx	356	7	resides	reside	VBZ
cord-002808-84np9brx	356	8	in	in	IN
cord-002808-84np9brx	356	9	a	a	DT
cord-002808-84np9brx	356	10	vesicular	vesicular	JJ
cord-002808-84np9brx	356	11	compartment	compartment	NN
cord-002808-84np9brx	356	12	throughout	throughout	IN
cord-002808-84np9brx	356	13	mitosis	mitosis	NN
cord-002808-84np9brx	357	1	Furin	furin	NN
cord-002808-84np9brx	357	2	-	-	HYPH
cord-002808-84np9brx	357	3	induced	induce	VBN
cord-002808-84np9brx	357	4	cleavage	cleavage	NN
cord-002808-84np9brx	357	5	and	and	CC
cord-002808-84np9brx	357	6	activation	activation	NN
cord-002808-84np9brx	357	7	of	of	IN
cord-002808-84np9brx	357	8	shiga	shiga	JJ
cord-002808-84np9brx	357	9	toxin	toxin	NN
cord-002808-84np9brx	357	10	Proteolytic	Proteolytic	NNP
cord-002808-84np9brx	357	11	activation	activation	NN
cord-002808-84np9brx	357	12	of	of	IN
cord-002808-84np9brx	357	13	bacterial	bacterial	JJ
cord-002808-84np9brx	357	14	toxins	toxin	NNS
cord-002808-84np9brx	357	15	by	by	IN
cord-002808-84np9brx	357	16	eukaryotic	eukaryotic	JJ
cord-002808-84np9brx	357	17	cells	cell	NNS
cord-002808-84np9brx	357	18	is	be	VBZ
cord-002808-84np9brx	357	19	performed	perform	VBN
cord-002808-84np9brx	357	20	by	by	IN
cord-002808-84np9brx	357	21	furin	furin	NN
cord-002808-84np9brx	357	22	and	and	CC
cord-002808-84np9brx	357	23	by	by	IN
cord-002808-84np9brx	357	24	additional	additional	JJ
cord-002808-84np9brx	357	25	cellular	cellular	JJ
cord-002808-84np9brx	357	26	proteases	protease	NNS
cord-002808-84np9brx	357	27	Fusion	fusion	NN
cord-002808-84np9brx	357	28	peptides	peptide	NNS
cord-002808-84np9brx	357	29	and	and	CC
cord-002808-84np9brx	357	30	the	the	DT
cord-002808-84np9brx	357	31	mechanism	mechanism	NN
cord-002808-84np9brx	357	32	of	of	IN
cord-002808-84np9brx	357	33	viral	viral	JJ
cord-002808-84np9brx	357	34	fusion	fusion	NN
cord-002808-84np9brx	357	35	Structure	structure	NN
cord-002808-84np9brx	357	36	and	and	CC
cord-002808-84np9brx	357	37	function	function	NN
cord-002808-84np9brx	357	38	of	of	IN
cord-002808-84np9brx	357	39	membrane	membrane	NN
cord-002808-84np9brx	357	40	fusion	fusion	NN
cord-002808-84np9brx	357	41	peptides	peptide	NNS
cord-002808-84np9brx	358	1	The	the	DT
cord-002808-84np9brx	358	2	complete	complete	JJ
cord-002808-84np9brx	358	3	influenza	influenza	NN
cord-002808-84np9brx	358	4	hemagglutinin	hemagglutinin	NN
cord-002808-84np9brx	358	5	fusion	fusion	NN
cord-002808-84np9brx	358	6	domain	domain	NN
cord-002808-84np9brx	358	7	adopts	adopt	VBZ
cord-002808-84np9brx	358	8	a	a	DT
cord-002808-84np9brx	358	9	tight	tight	JJ
cord-002808-84np9brx	358	10	helical	helical	JJ
cord-002808-84np9brx	358	11	hairpin	hairpin	NN
cord-002808-84np9brx	358	12	arrangement	arrangement	NN
cord-002808-84np9brx	358	13	at	at	IN
cord-002808-84np9brx	358	14	the	the	DT
cord-002808-84np9brx	358	15	lipid	lipid	NN
cord-002808-84np9brx	358	16	:	:	:
cord-002808-84np9brx	358	17	Water	water	NN
cord-002808-84np9brx	358	18	interface	interface	NN
cord-002808-84np9brx	358	19	De	De	NNP
cord-002808-84np9brx	358	20	novo	novo	NN
cord-002808-84np9brx	358	21	design	design	NN
cord-002808-84np9brx	358	22	of	of	IN
cord-002808-84np9brx	358	23	conformationally	conformationally	RB
cord-002808-84np9brx	358	24	flexible	flexible	JJ
cord-002808-84np9brx	358	25	transmembrane	transmembrane	NN
cord-002808-84np9brx	358	26	peptides	peptide	NNS
cord-002808-84np9brx	358	27	driving	drive	VBG
cord-002808-84np9brx	358	28	membrane	membrane	NN
cord-002808-84np9brx	358	29	fusion	fusion	NN
cord-002808-84np9brx	358	30	Structures	structure	NNS
cord-002808-84np9brx	358	31	and	and	CC
cord-002808-84np9brx	358	32	mechanisms	mechanism	NNS
cord-002808-84np9brx	358	33	of	of	IN
cord-002808-84np9brx	358	34	viral	viral	JJ
cord-002808-84np9brx	358	35	membrane	membrane	NN
cord-002808-84np9brx	358	36	fusion	fusion	NN
cord-002808-84np9brx	358	37	proteins	protein	NNS
cord-002808-84np9brx	358	38	:	:	:
cord-002808-84np9brx	359	1	Multiple	multiple	JJ
cord-002808-84np9brx	359	2	variations	variation	NNS
cord-002808-84np9brx	359	3	on	on	IN
cord-002808-84np9brx	359	4	a	a	DT
cord-002808-84np9brx	359	5	common	common	JJ
cord-002808-84np9brx	359	6	theme	theme	NN
cord-002808-84np9brx	359	7	Analysis	Analysis	NNP
cord-002808-84np9brx	359	8	of	of	IN
cord-002808-84np9brx	359	9	the	the	DT
cord-002808-84np9brx	359	10	γ	γ	NNP
cord-002808-84np9brx	359	11	-	-	HYPH
cord-002808-84np9brx	359	12	secretase	secretase	NNP
cord-002808-84np9brx	359	13	interactome	interactome	NNP
cord-002808-84np9brx	359	14	and	and	CC
cord-002808-84np9brx	359	15	validation	validation	NN
cord-002808-84np9brx	359	16	of	of	IN
cord-002808-84np9brx	359	17	its	-PRON-	PRP$
cord-002808-84np9brx	359	18	association	association	NN
cord-002808-84np9brx	359	19	with	with	IN
cord-002808-84np9brx	359	20	tetraspanin	tetraspanin	NNP
cord-002808-84np9brx	359	21	-	-	HYPH
cord-002808-84np9brx	359	22	enriched	enrich	VBN
cord-002808-84np9brx	359	23	microdomains	microdomain	NNS
cord-002808-84np9brx	359	24	Structure	Structure	NNP
cord-002808-84np9brx	359	25	,	,	,
cord-002808-84np9brx	359	26	mechanism	mechanism	NN
cord-002808-84np9brx	359	27	and	and	CC
cord-002808-84np9brx	359	28	inhibition	inhibition	NN
cord-002808-84np9brx	359	29	of	of	IN
cord-002808-84np9brx	359	30	gamma	gamma	NN
cord-002808-84np9brx	359	31	-	-	HYPH
cord-002808-84np9brx	359	32	secretase	secretase	NN
cord-002808-84np9brx	359	33	and	and	CC
cord-002808-84np9brx	359	34	presenilin	presenilin	NN
cord-002808-84np9brx	359	35	-	-	HYPH
cord-002808-84np9brx	359	36	like	like	JJ
cord-002808-84np9brx	359	37	proteases	protease	NNS
cord-002808-84np9brx	359	38	Differential	differential	JJ
cord-002808-84np9brx	359	39	effects	effect	NNS
cord-002808-84np9brx	359	40	of	of	IN
cord-002808-84np9brx	359	41	inhibitors	inhibitor	NNS
cord-002808-84np9brx	359	42	on	on	IN
cord-002808-84np9brx	359	43	the	the	DT
cord-002808-84np9brx	359	44	γ	γ	NNP
cord-002808-84np9brx	359	45	-	-	HYPH
cord-002808-84np9brx	359	46	secretase	secretase	NNP
cord-002808-84np9brx	359	47	complex	complex	NN
cord-002808-84np9brx	359	48	.	.	.
cord-002808-84np9brx	360	1	Mechanistic	mechanistic	JJ
cord-002808-84np9brx	360	2	implications	implication	NNS
cord-002808-84np9brx	361	1	Structural	structural	JJ
cord-002808-84np9brx	361	2	biology	biology	NN
cord-002808-84np9brx	361	3	of	of	IN
cord-002808-84np9brx	361	4	presenilin	presenilin	NN
cord-002808-84np9brx	361	5	1	1	CD
cord-002808-84np9brx	361	6	complexes	complex	NNS
cord-002808-84np9brx	362	1	The	the	DT
cord-002808-84np9brx	362	2	cellular	cellular	JJ
cord-002808-84np9brx	362	3	endosomal	endosomal	NNP
cord-002808-84np9brx	362	4	protein	protein	NN
cord-002808-84np9brx	362	5	stannin	stannin	NNP
cord-002808-84np9brx	362	6	inhibits	inhibit	VBZ
cord-002808-84np9brx	362	7	intracellular	intracellular	JJ
cord-002808-84np9brx	362	8	trafficking	trafficking	NN
cord-002808-84np9brx	362	9	of	of	IN
cord-002808-84np9brx	362	10	human	human	JJ
cord-002808-84np9brx	362	11	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	362	12	during	during	IN
cord-002808-84np9brx	363	1	virus	virus	NN
cord-002808-84np9brx	363	2	entry	entry	NN
cord-002808-84np9brx	363	3	α	α	NNP
cord-002808-84np9brx	363	4	-	-	HYPH
cord-002808-84np9brx	363	5	defensin	defensin	NNP
cord-002808-84np9brx	363	6	HD5	HD5	NNP
cord-002808-84np9brx	363	7	inhibits	inhibit	VBZ
cord-002808-84np9brx	363	8	human	human	JJ
cord-002808-84np9brx	363	9	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	363	10	16	16	CD
cord-002808-84np9brx	363	11	infection	infection	NN
cord-002808-84np9brx	363	12	via	via	IN
cord-002808-84np9brx	363	13	capsid	capsid	JJ
cord-002808-84np9brx	363	14	stabilization	stabilization	NN
cord-002808-84np9brx	363	15	and	and	CC
cord-002808-84np9brx	363	16	redirection	redirection	NN
cord-002808-84np9brx	363	17	to	to	IN
cord-002808-84np9brx	363	18	the	the	DT
cord-002808-84np9brx	363	19	lysosome	lysosome	NN
cord-002808-84np9brx	364	1	Interferon	interferon	NN
cord-002808-84np9brx	364	2	gamma	gamma	NN
cord-002808-84np9brx	364	3	prevents	prevent	VBZ
cord-002808-84np9brx	364	4	infectious	infectious	JJ
cord-002808-84np9brx	364	5	entry	entry	NN
cord-002808-84np9brx	364	6	of	of	IN
cord-002808-84np9brx	364	7	human	human	JJ
cord-002808-84np9brx	364	8	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	364	9	16	16	CD
cord-002808-84np9brx	364	10	via	via	IN
cord-002808-84np9brx	364	11	an	an	DT
cord-002808-84np9brx	364	12	L2-dependent	L2-dependent	NNP
cord-002808-84np9brx	364	13	mechanism	mechanism	NN
cord-002808-84np9brx	364	14	Human	human	JJ
cord-002808-84np9brx	364	15	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	364	16	type	type	NN
cord-002808-84np9brx	364	17	16	16	CD
cord-002808-84np9brx	364	18	does	do	VBZ
cord-002808-84np9brx	364	19	not	not	RB
cord-002808-84np9brx	364	20	require	require	VB
cord-002808-84np9brx	364	21	cathepsin	cathepsin	NN
cord-002808-84np9brx	364	22	L	l	NN
cord-002808-84np9brx	364	23	or	or	CC
cord-002808-84np9brx	364	24	B	b	NN
cord-002808-84np9brx	364	25	for	for	IN
cord-002808-84np9brx	364	26	infection	infection	NN
cord-002808-84np9brx	365	1	A	a	DT
cord-002808-84np9brx	365	2	two	two	CD
cord-002808-84np9brx	365	3	-	-	HYPH
cord-002808-84np9brx	365	4	hybrid	hybrid	NN
cord-002808-84np9brx	365	5	screen	screen	NN
cord-002808-84np9brx	365	6	identifies	identify	VBZ
cord-002808-84np9brx	365	7	cathepsins	cathepsin	NNS
cord-002808-84np9brx	365	8	B	B	NNP
cord-002808-84np9brx	365	9	and	and	CC
cord-002808-84np9brx	365	10	L	L	NNP
cord-002808-84np9brx	365	11	as	as	IN
cord-002808-84np9brx	365	12	uncoating	uncoating	NN
cord-002808-84np9brx	365	13	factors	factor	NNS
cord-002808-84np9brx	365	14	for	for	IN
cord-002808-84np9brx	365	15	adeno	adeno	NN
cord-002808-84np9brx	365	16	-	-	HYPH
cord-002808-84np9brx	365	17	associated	associate	VBN
cord-002808-84np9brx	365	18	virus	virus	NN
cord-002808-84np9brx	365	19	2	2	CD
cord-002808-84np9brx	365	20	and	and	CC
cord-002808-84np9brx	365	21	8	8	CD
cord-002808-84np9brx	365	22	Cathepsin	Cathepsin	NNP
cord-002808-84np9brx	365	23	L	L	NNP
cord-002808-84np9brx	365	24	and	and	CC
cord-002808-84np9brx	365	25	cathepsin	cathepsin	NN
cord-002808-84np9brx	365	26	B	b	NN
cord-002808-84np9brx	366	1	mediate	mediate	VB
cord-002808-84np9brx	366	2	reovirus	reovirus	NNP
cord-002808-84np9brx	366	3	disassembly	disassembly	NN
cord-002808-84np9brx	366	4	in	in	IN
cord-002808-84np9brx	366	5	murine	murine	JJ
cord-002808-84np9brx	366	6	fibroblast	fibroblast	NN
cord-002808-84np9brx	366	7	cells	cell	NNS
cord-002808-84np9brx	367	1	Vimentin	Vimentin	NNP
cord-002808-84np9brx	367	2	modulates	modulate	VBZ
cord-002808-84np9brx	367	3	infectious	infectious	JJ
cord-002808-84np9brx	367	4	internalization	internalization	NN
cord-002808-84np9brx	367	5	of	of	IN
cord-002808-84np9brx	367	6	human	human	JJ
cord-002808-84np9brx	367	7	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	367	8	16	16	CD
cord-002808-84np9brx	367	9	pseudovirions	pseudovirion	NNS
cord-002808-84np9brx	367	10	Current	current	JJ
cord-002808-84np9brx	367	11	understanding	understanding	NN
cord-002808-84np9brx	367	12	of	of	IN
cord-002808-84np9brx	367	13	the	the	DT
cord-002808-84np9brx	367	14	mechanism	mechanism	NN
cord-002808-84np9brx	367	15	of	of	IN
cord-002808-84np9brx	367	16	HPV	HPV	NNP
cord-002808-84np9brx	367	17	infection	infection	NN
cord-002808-84np9brx	368	1	How	how	WRB
cord-002808-84np9brx	368	2	viruses	virus	NNS
cord-002808-84np9brx	368	3	enter	enter	VBP
cord-002808-84np9brx	368	4	animal	animal	NN
cord-002808-84np9brx	368	5	cells	cell	NNS
cord-002808-84np9brx	368	6	Penetration	penetration	NN
cord-002808-84np9brx	368	7	of	of	IN
cord-002808-84np9brx	368	8	nonenveloped	nonenveloped	JJ
cord-002808-84np9brx	368	9	viruses	virus	NNS
cord-002808-84np9brx	368	10	into	into	IN
cord-002808-84np9brx	368	11	the	the	DT
cord-002808-84np9brx	368	12	cytoplasm	cytoplasm	JJ
cord-002808-84np9brx	368	13	Establishment	Establishment	NNP
cord-002808-84np9brx	368	14	of	of	IN
cord-002808-84np9brx	368	15	human	human	JJ
cord-002808-84np9brx	368	16	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	368	17	infection	infection	NN
cord-002808-84np9brx	368	18	requires	require	VBZ
cord-002808-84np9brx	368	19	cell	cell	NN
cord-002808-84np9brx	368	20	cycle	cycle	NN
cord-002808-84np9brx	368	21	progression	progression	NN
cord-002808-84np9brx	368	22	Passage	passage	NN
cord-002808-84np9brx	368	23	through	through	IN
cord-002808-84np9brx	368	24	mitosis	mitosis	NN
cord-002808-84np9brx	368	25	is	be	VBZ
cord-002808-84np9brx	368	26	required	require	VBN
cord-002808-84np9brx	368	27	for	for	IN
cord-002808-84np9brx	368	28	oncoretroviruses	oncoretroviruse	NNS
cord-002808-84np9brx	368	29	but	but	CC
cord-002808-84np9brx	368	30	not	not	RB
cord-002808-84np9brx	368	31	for	for	IN
cord-002808-84np9brx	368	32	the	the	DT
cord-002808-84np9brx	368	33	human	human	JJ
cord-002808-84np9brx	368	34	immunodeficiency	immunodeficiency	NN
cord-002808-84np9brx	368	35	virus	virus	NN
cord-002808-84np9brx	368	36	Use	use	NN
cord-002808-84np9brx	368	37	of	of	IN
cord-002808-84np9brx	368	38	peptide	peptide	JJ
cord-002808-84np9brx	368	39	libraries	library	NNS
cord-002808-84np9brx	368	40	to	to	TO
cord-002808-84np9brx	368	41	map	map	VB
cord-002808-84np9brx	368	42	the	the	DT
cord-002808-84np9brx	368	43	substrate	substrate	JJ
cord-002808-84np9brx	368	44	specificity	specificity	NN
cord-002808-84np9brx	368	45	of	of	IN
cord-002808-84np9brx	368	46	a	a	DT
cord-002808-84np9brx	368	47	peptide	peptide	NN
cord-002808-84np9brx	368	48	-	-	HYPH
cord-002808-84np9brx	368	49	modifying	modify	VBG
cord-002808-84np9brx	368	50	enzyme	enzyme	NN
cord-002808-84np9brx	368	51	:	:	:
cord-002808-84np9brx	368	52	A	a	DT
cord-002808-84np9brx	368	53	13	13	CD
cord-002808-84np9brx	368	54	residue	residue	NN
cord-002808-84np9brx	368	55	consensus	consensus	NN
cord-002808-84np9brx	368	56	peptide	peptide	NN
cord-002808-84np9brx	368	57	specifies	specify	VBZ
cord-002808-84np9brx	368	58	biotinylation	biotinylation	NN
cord-002808-84np9brx	368	59	in	in	IN
cord-002808-84np9brx	368	60	Escherichia	Escherichia	NNP
cord-002808-84np9brx	368	61	coli	coli	NNS
cord-002808-84np9brx	368	62	Mechanism	mechanism	NN
cord-002808-84np9brx	368	63	of	of	IN
cord-002808-84np9brx	368	64	diphtheria	diphtheria	NN
cord-002808-84np9brx	368	65	toxin	toxin	NN
cord-002808-84np9brx	368	66	catalytic	catalytic	JJ
cord-002808-84np9brx	368	67	domain	domain	NN
cord-002808-84np9brx	368	68	delivery	delivery	NN
cord-002808-84np9brx	368	69	to	to	IN
cord-002808-84np9brx	368	70	the	the	DT
cord-002808-84np9brx	368	71	eukaryotic	eukaryotic	JJ
cord-002808-84np9brx	368	72	cell	cell	NN
cord-002808-84np9brx	368	73	cytosol	cytosol	NN
cord-002808-84np9brx	368	74	and	and	CC
cord-002808-84np9brx	368	75	the	the	DT
cord-002808-84np9brx	368	76	cellular	cellular	JJ
cord-002808-84np9brx	368	77	factors	factor	NNS
cord-002808-84np9brx	368	78	that	that	WDT
cord-002808-84np9brx	368	79	directly	directly	RB
cord-002808-84np9brx	368	80	participate	participate	VBP
cord-002808-84np9brx	368	81	in	in	IN
cord-002808-84np9brx	368	82	the	the	DT
cord-002808-84np9brx	368	83	process	process	NN
cord-002808-84np9brx	368	84	On	on	IN
cord-002808-84np9brx	368	85	the	the	DT
cord-002808-84np9brx	368	86	translocation	translocation	NN
cord-002808-84np9brx	368	87	of	of	IN
cord-002808-84np9brx	368	88	botulinum	botulinum	NN
cord-002808-84np9brx	368	89	and	and	CC
cord-002808-84np9brx	368	90	tetanus	tetanus	NN
cord-002808-84np9brx	368	91	neurotoxins	neurotoxin	NNS
cord-002808-84np9brx	368	92	across	across	IN
cord-002808-84np9brx	368	93	the	the	DT
cord-002808-84np9brx	368	94	membrane	membrane	NN
cord-002808-84np9brx	368	95	of	of	IN
cord-002808-84np9brx	368	96	acidic	acidic	JJ
cord-002808-84np9brx	368	97	intracellular	intracellular	JJ
cord-002808-84np9brx	368	98	compartments	compartment	NNS
cord-002808-84np9brx	368	99	Establishment	Establishment	NNP
cord-002808-84np9brx	368	100	of	of	IN
cord-002808-84np9brx	368	101	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	368	102	infection	infection	NN
cord-002808-84np9brx	368	103	is	be	VBZ
cord-002808-84np9brx	368	104	enhanced	enhance	VBN
cord-002808-84np9brx	368	105	by	by	IN
cord-002808-84np9brx	368	106	promyelocytic	promyelocytic	JJ
cord-002808-84np9brx	368	107	leukemia	leukemia	NN
cord-002808-84np9brx	368	108	protein	protein	NN
cord-002808-84np9brx	368	109	(	(	-LRB-
cord-002808-84np9brx	368	110	PML	PML	NNP
cord-002808-84np9brx	368	111	)	)	-RRB-
cord-002808-84np9brx	368	112	expression	expression	NN
cord-002808-84np9brx	369	1	PML	PML	NNP
cord-002808-84np9brx	369	2	nuclear	nuclear	JJ
cord-002808-84np9brx	369	3	bodies	body	NNS
cord-002808-84np9brx	370	1	PML	PML	NNP
cord-002808-84np9brx	370	2	nuclear	nuclear	JJ
cord-002808-84np9brx	370	3	bodies	body	NNS
cord-002808-84np9brx	370	4	:	:	:
cord-002808-84np9brx	370	5	Regulation	regulation	NN
cord-002808-84np9brx	370	6	,	,	,
cord-002808-84np9brx	370	7	function	function	NN
cord-002808-84np9brx	370	8	and	and	CC
cord-002808-84np9brx	370	9	therapeutic	therapeutic	JJ
cord-002808-84np9brx	370	10	perspectives	perspective	NNS
cord-002808-84np9brx	371	1	Emerging	emerge	VBG
cord-002808-84np9brx	371	2	role	role	NN
cord-002808-84np9brx	371	3	of	of	IN
cord-002808-84np9brx	371	4	PML	PML	NNP
cord-002808-84np9brx	371	5	nuclear	nuclear	JJ
cord-002808-84np9brx	371	6	bodies	body	NNS
cord-002808-84np9brx	371	7	in	in	IN
cord-002808-84np9brx	371	8	innate	innate	JJ
cord-002808-84np9brx	371	9	immune	immune	NN
cord-002808-84np9brx	371	10	signaling	signal	VBG
cord-002808-84np9brx	371	11	Dynamics	dynamic	NNS
cord-002808-84np9brx	371	12	of	of	IN
cord-002808-84np9brx	371	13	component	component	NN
cord-002808-84np9brx	371	14	exchange	exchange	NN
cord-002808-84np9brx	371	15	at	at	IN
cord-002808-84np9brx	371	16	PML	PML	NNP
cord-002808-84np9brx	371	17	nuclear	nuclear	JJ
cord-002808-84np9brx	371	18	bodies	body	NNS
cord-002808-84np9brx	372	1	Oxidative	oxidative	JJ
cord-002808-84np9brx	372	2	stress	stress	NN
cord-002808-84np9brx	372	3	-	-	HYPH
cord-002808-84np9brx	372	4	induced	induce	VBN
cord-002808-84np9brx	372	5	assembly	assembly	NN
cord-002808-84np9brx	372	6	of	of	IN
cord-002808-84np9brx	372	7	pml	pml	NNP
cord-002808-84np9brx	372	8	nuclear	nuclear	JJ
cord-002808-84np9brx	372	9	bodies	body	NNS
cord-002808-84np9brx	372	10	controls	control	VBZ
cord-002808-84np9brx	372	11	sumoylation	sumoylation	NN
cord-002808-84np9brx	372	12	of	of	IN
cord-002808-84np9brx	372	13	partner	partner	NN
cord-002808-84np9brx	372	14	proteins	protein	NNS
cord-002808-84np9brx	372	15	DNA	dna	NN
cord-002808-84np9brx	372	16	viruses	virus	NNS
cord-002808-84np9brx	372	17	and	and	CC
cord-002808-84np9brx	372	18	viral	viral	JJ
cord-002808-84np9brx	372	19	proteins	protein	NNS
cord-002808-84np9brx	372	20	that	that	WDT
cord-002808-84np9brx	372	21	interact	interact	VBP
cord-002808-84np9brx	372	22	with	with	IN
cord-002808-84np9brx	372	23	PML	PML	NNP
cord-002808-84np9brx	372	24	nuclear	nuclear	JJ
cord-002808-84np9brx	372	25	bodies	body	NNS
cord-002808-84np9brx	372	26	PML	PML	NNP
cord-002808-84np9brx	372	27	and	and	CC
cord-002808-84np9brx	372	28	PML	PML	NNP
cord-002808-84np9brx	372	29	nuclear	nuclear	JJ
cord-002808-84np9brx	372	30	bodies	body	NNS
cord-002808-84np9brx	372	31	:	:	:
cord-002808-84np9brx	372	32	Implications	implication	NNS
cord-002808-84np9brx	372	33	in	in	IN
cord-002808-84np9brx	372	34	antiviral	antiviral	JJ
cord-002808-84np9brx	372	35	defence	defence	NN
cord-002808-84np9brx	372	36	Reorganization	Reorganization	NNP
cord-002808-84np9brx	372	37	of	of	IN
cord-002808-84np9brx	372	38	nuclear	nuclear	JJ
cord-002808-84np9brx	372	39	domain	domain	NN
cord-002808-84np9brx	372	40	10	10	CD
cord-002808-84np9brx	372	41	induced	induce	VBN
cord-002808-84np9brx	372	42	by	by	IN
cord-002808-84np9brx	372	43	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	372	44	capsid	capsid	NN
cord-002808-84np9brx	372	45	protein	protein	NN
cord-002808-84np9brx	372	46	L2	L2	NNP
cord-002808-84np9brx	372	47	Dissection	Dissection	NNP
cord-002808-84np9brx	372	48	of	of	IN
cord-002808-84np9brx	372	49	human	human	JJ
cord-002808-84np9brx	372	50	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	372	51	type	type	NN
cord-002808-84np9brx	372	52	33	33	CD
cord-002808-84np9brx	372	53	L2	l2	NN
cord-002808-84np9brx	372	54	domains	domain	NNS
cord-002808-84np9brx	372	55	involved	involve	VBN
cord-002808-84np9brx	372	56	in	in	IN
cord-002808-84np9brx	372	57	nuclear	nuclear	JJ
cord-002808-84np9brx	372	58	domains	domain	NNS
cord-002808-84np9brx	372	59	(	(	-LRB-
cord-002808-84np9brx	372	60	ND	ND	NNP
cord-002808-84np9brx	372	61	)	)	-RRB-
cord-002808-84np9brx	372	62	10	10	CD
cord-002808-84np9brx	372	63	homing	homing	NN
cord-002808-84np9brx	372	64	and	and	CC
cord-002808-84np9brx	372	65	reorganization	reorganization	NN
cord-002808-84np9brx	373	1	An	an	DT
cord-002808-84np9brx	373	2	L2	l2	NN
cord-002808-84np9brx	373	3	sumo	sumo	NN
cord-002808-84np9brx	373	4	interacting	interact	VBG
cord-002808-84np9brx	373	5	motif	motif	NN
cord-002808-84np9brx	373	6	is	be	VBZ
cord-002808-84np9brx	373	7	important	important	JJ
cord-002808-84np9brx	373	8	for	for	IN
cord-002808-84np9brx	373	9	PML	PML	NNP
cord-002808-84np9brx	373	10	localization	localization	NN
cord-002808-84np9brx	373	11	and	and	CC
cord-002808-84np9brx	373	12	infection	infection	NN
cord-002808-84np9brx	373	13	of	of	IN
cord-002808-84np9brx	373	14	human	human	JJ
cord-002808-84np9brx	373	15	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	373	16	type	type	NN
cord-002808-84np9brx	373	17	16	16	CD
cord-002808-84np9brx	373	18	Modification	modification	NN
cord-002808-84np9brx	373	19	of	of	IN
cord-002808-84np9brx	373	20	human	human	JJ
cord-002808-84np9brx	373	21	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	373	22	minor	minor	JJ
cord-002808-84np9brx	373	23	capsid	capsid	NN
cord-002808-84np9brx	373	24	protein	protein	NN
cord-002808-84np9brx	373	25	L2	l2	NN
cord-002808-84np9brx	373	26	by	by	IN
cord-002808-84np9brx	373	27	sumoylation	sumoylation	NN
cord-002808-84np9brx	373	28	Factors	factor	NNS
cord-002808-84np9brx	373	29	influencing	influence	VBG
cord-002808-84np9brx	373	30	subcellular	subcellular	JJ
cord-002808-84np9brx	373	31	localization	localization	NN
cord-002808-84np9brx	373	32	of	of	IN
cord-002808-84np9brx	373	33	the	the	DT
cord-002808-84np9brx	373	34	human	human	JJ
cord-002808-84np9brx	373	35	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	373	36	L2	L2	NNP
cord-002808-84np9brx	373	37	minor	minor	JJ
cord-002808-84np9brx	373	38	structural	structural	JJ
cord-002808-84np9brx	373	39	protein	protein	NN
cord-002808-84np9brx	373	40	Sp100	Sp100	NNP
cord-002808-84np9brx	374	1	provides	provide	VBZ
cord-002808-84np9brx	374	2	intrinsic	intrinsic	JJ
cord-002808-84np9brx	374	3	immunity	immunity	NN
cord-002808-84np9brx	374	4	against	against	IN
cord-002808-84np9brx	374	5	human	human	JJ
cord-002808-84np9brx	374	6	papillomavirus	papillomavirus	NN
cord-002808-84np9brx	374	7	infection	infection	NN
cord-002808-84np9brx	374	8	Live	live	VBP
cord-002808-84np9brx	374	9	cell	cell	NN
cord-002808-84np9brx	374	10	dynamics	dynamic	NNS
cord-002808-84np9brx	374	11	of	of	IN
cord-002808-84np9brx	374	12	promyelocytic	promyelocytic	NNP
cord-002808-84np9brx	374	13	leukemia	leukemia	NN
cord-002808-84np9brx	374	14	nuclear	nuclear	JJ
cord-002808-84np9brx	374	15	bodies	body	NNS
cord-002808-84np9brx	374	16	upon	upon	IN
cord-002808-84np9brx	374	17	entry	entry	NN
cord-002808-84np9brx	374	18	into	into	IN
cord-002808-84np9brx	374	19	and	and	CC
cord-002808-84np9brx	374	20	exit	exit	NN
cord-002808-84np9brx	374	21	from	from	IN
cord-002808-84np9brx	374	22	mitosis	mitosis	NN
cord-002808-84np9brx	375	1	Sincere	sincere	JJ
cord-002808-84np9brx	375	2	apologies	apology	NNS
cord-002808-84np9brx	375	3	to	to	IN
cord-002808-84np9brx	375	4	all	all	DT
cord-002808-84np9brx	375	5	whose	whose	WP$
cord-002808-84np9brx	375	6	work	work	NN
cord-002808-84np9brx	375	7	was	be	VBD
cord-002808-84np9brx	375	8	neither	neither	CC
cord-002808-84np9brx	375	9	discussed	discuss	VBN
cord-002808-84np9brx	375	10	nor	nor	CC
cord-002808-84np9brx	375	11	cited	cite	VBN
cord-002808-84np9brx	375	12	due	due	IN
cord-002808-84np9brx	375	13	to	to	IN
cord-002808-84np9brx	375	14	space	space	NN
cord-002808-84np9brx	375	15	limitations	limitation	NNS
cord-002808-84np9brx	375	16	.	.	.
cord-002808-84np9brx	376	1	I	-PRON-	PRP
cord-002808-84np9brx	376	2	thank	thank	VBP
cord-002808-84np9brx	376	3	Koenraad	Koenraad	NNP
cord-002808-84np9brx	376	4	Van	Van	NNP
cord-002808-84np9brx	376	5	Doorslaer	Doorslaer	NNP
cord-002808-84np9brx	376	6	,	,	,
cord-002808-84np9brx	376	7	Brittany	Brittany	NNP
cord-002808-84np9brx	376	8	Forte	Forte	NNP
cord-002808-84np9brx	376	9	,	,	,
cord-002808-84np9brx	376	10	Shuaizhi	Shuaizhi	NNP
cord-002808-84np9brx	376	11	Li	Li	NNP
cord-002808-84np9brx	376	12	,	,	,
cord-002808-84np9brx	376	13	and	and	CC
cord-002808-84np9brx	376	14	Matthew	Matthew	NNP
cord-002808-84np9brx	376	15	Bronnimann	Bronnimann	NNP
cord-002808-84np9brx	376	16	for	for	IN
cord-002808-84np9brx	376	17	critical	critical	JJ
cord-002808-84np9brx	376	18	reading	reading	NN
cord-002808-84np9brx	376	19	of	of	IN
cord-002808-84np9brx	376	20	the	the	DT
cord-002808-84np9brx	376	21	manuscript	manuscript	NN
cord-002808-84np9brx	376	22	.	.	.
cord-002808-84np9brx	377	1	Samuel	Samuel	NNP
cord-002808-84np9brx	377	2	K.	K.	NNP
cord-002808-84np9brx	377	3	Campos	Campos	NNP
cord-002808-84np9brx	377	4	is	be	VBZ
cord-002808-84np9brx	377	5	supported	support	VBN
cord-002808-84np9brx	377	6	by	by	IN
cord-002808-84np9brx	377	7	grant	grant	NN
cord-002808-84np9brx	377	8	1R01AI108751	1r01ai108751	CD
cord-002808-84np9brx	377	9	from	from	IN
cord-002808-84np9brx	377	10	the	the	DT
cord-002808-84np9brx	377	11	National	National	NNP
cord-002808-84np9brx	377	12	Institute	Institute	NNP
cord-002808-84np9brx	377	13	for	for	IN
cord-002808-84np9brx	377	14	Allergy	Allergy	NNP
cord-002808-84np9brx	377	15	and	and	CC
cord-002808-84np9brx	377	16	Infectious	Infectious	NNP
cord-002808-84np9brx	377	17	Diseases	Diseases	NNPS
cord-002808-84np9brx	377	18	.	.	.