id author title date pages extension mime words sentences flesch summary cache txt cord-351228-hpo8bboi Wasilenko, Shawn T. Is there a Role for Cyclophilin Inhibitors in the Management of Primary Biliary Cirrhosis? 2013-01-24 .txt text/plain 4260 210 36 Herein, we discuss the evidence supporting the role of MMTV-like human betaretrovirus in the development of PBC and de novo AIH and speculate on the possibility that the agent may be associated with disease following transplantation. Nevertheless, a major conclusion of most series documenting outcomes in patients with PBC following liver transplantation is that CsA is associated with a lower incidence of recurrent disease [10] [11] [12] [13] [14] [15] [16] 18] . Other agents, such as hepatitis C virus (HCV) rely on cyclophilin A interactions with viral components of the replication complex to produce RNA transcripts, a process also blocked by CsA [64] [65] [66] [67] [68] [69] [70] [71] . Cyclosporine A protects against primary biliary cirrhosis recurrence after liver transplantation Long-term follow-up after recurrence of primary biliary cirrhosis after liver transplantation in 100 patients De novo autoimmune hepatitis following liver transplantation for primary biliary cirrhosis ./cache/cord-351228-hpo8bboi.txt ./txt/cord-351228-hpo8bboi.txt