id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324617-yok7mh70	Andreata-Santos, Robert	Transcutaneous Administration of Dengue Vaccines	2020-05-06		.txt	text/plain	6337	283	44	Vaccines against type 2 Dengue virus particles (DENV2 New Guinea C (NGC) strain) combined with enterotoxigenic Escherichia coli (ETEC) heat-labile toxin (LT) were administered to BALB/c mice in a three-dose immunization regimen via the TC route. Our results showed that mice vaccinated either via the TC or ID routes developed similar protective immunity, as measured after lethal challenges with the DENV2 NGC strain. The addition of LT1 to the vaccines significantly enhanced the DENV2-specific serum IgG responses elicited in the mice immunized via the TC or ID route, with the maximal values reached two weeks after the third vaccine dose ( Figure 1A ,B). The ID-immunized mice showed significant differences in DENV2-specific serum IgG responses in the presence of LT1, particularly in the group immunized with 50 µg of the tested antigen ( Figure 1D ). The ID-immunized mice showed significant differences in DENV2-specific serum IgG responses in the presence of LT1, particularly in the group immunized with 50 µg of the tested antigen ( Figure 1D ).	./cache/cord-324617-yok7mh70.txt	./txt/cord-324617-yok7mh70.txt