id author title date pages extension mime words sentences flesch summary cache txt cord-297834-me1ajoyb Schountz, Tony Hantavirus Immunology of Rodent Reservoirs: Current Status and Future Directions 2014-03-14 .txt text/plain 6425 334 38 The immune response is energetically expensive for wild animals, thus the findings of experimental studies will be critical for understanding the ecoimmunology of reservoir hosts of hantaviruses [6, 7] , and experiments using wild rodents in natural or semi-natural environments [8, 9] will be required to validate laboratory findings. Currently, three laboratory infection systems have been developed to study hantavirus infections of reservoir hosts: Seoul virus (SEOV) infection of the Norway rat (Rattus norvegicus), Puumala virus (PUUV) infection of the bank vole (Myodes glareolus), and Sin Nombre virus (SNV) infection of the deer mouse (Peromyscus maniculatus) [12, 14, 16] . Experimental data have also shown that patterns of the expression of genes related to the immune response are different in infected males and females [32] , and it is likely these differences have important roles in hantavirus ecology. ./cache/cord-297834-me1ajoyb.txt ./txt/cord-297834-me1ajoyb.txt