id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-295044-eva0soja	Hutson, Christina L.	Monkeypox Virus Infections in Small Animal Models for Evaluation of Anti-Poxvirus Agents	2010-12-20		.txt	text/plain	4656	223	52	The disease pathogenesis has been conjectured and modeled largely from animal studies; initial models were using ectromelia infection of mice; some kinetic observations of virus shedding and viremia have been made in human studies of smallpox and monkeypox. challenged adult common squirrels (Sciurus vulgaris) with 10 6 pfu of MPXV Z-249 (Congo Basin clade) via IN, oral or scarification routes of infection [9] . A follow-up study found the LD 50 for the prairie dog MPXV model is approximately a hundred-times lower for the Congo Basin clade compared to the West African clade (5.9 × 10 3 and 1.29 × 10 5 , respectively) [15] , utilizing an IN route of infection. A prairie dog animal model of systemic orthopoxvirus disease using West African and Congo Basin strains of monkeypox virus Dosage comparison of Congo Basin and West African strains of monkeypox virus using a prairie dog animal model of systemic orthopoxvirus disease	./cache/cord-295044-eva0soja.txt	./txt/cord-295044-eva0soja.txt