id author title date pages extension mime words sentences flesch summary cache txt cord-294842-aesiff1f Romero-Brey, Inés Membranous Replication Factories Induced by Plus-Strand RNA Viruses 2014-07-22 .txt text/plain 11038 520 40 Three-dimensional reconstructions of the WNV KUN replication sites revealed an intimate association of the rough ER (rER) with the bounding membrane of the VPs [20] (Figure 2B ), resembling the vesicles observed in DENV-infected cells. In cells infected with TBEV, one of the most important tick-transmitted viruses in Europe and Asia, virus particles and membrane-connected vesicles were also observed inside the ER [25] , similar to what was described for DENV and WNV KUN . Importantly, pulse-radiolabeling experiments localized sites of active RNA replication to the outer surface of single-membrane tubules [71] and isolation of the membranous replication factories and their subsequent visualization by EM revealed that they form rosette-like structures composed of virus-induced cytoplasmic vesicles [124] . Formation of plant RNA virus replication complexes on membranes: Role of an endoplasmic reticulum-targeted viral protein ./cache/cord-294842-aesiff1f.txt ./txt/cord-294842-aesiff1f.txt