id author title date pages extension mime words sentences flesch summary cache txt cord-258536-qnn9hp8e Cong, Yingying The Interaction between Nidovirales and Autophagy Components 2017-07-11 .txt text/plain 6566 358 44 The nsp proteins interfere with the host defenses but also induce the formation of double-membrane vesicles (DMVs) and convoluted membranes, on which they collectively form the replication-transcription complexes (RTCs) [19, 20] (Figure 2 , steps 2, 3, and 4). These complexes mediate the synthesis of the genomic RNA and a nested set of subgenomic RNAs that directs the translation of the structural proteins (the nucleocapsid N protein, the membrane M protein, the envelope E protein and the spike S protein) and some accessory proteins, like the hemagglutinin esterase in the case of Severe Acute Respiratory Syndrome (SARS)-CoV or Mouse Hepatitis Virus (MHV) [21] [22] [23] (Figure 2 , steps 5 and 6). Infected cells displayed the presence of a higher number of autophagosome-like double-membrane vesicles, an accumulation of green fluorescent protein (GFP)-LC3-positive puncta and higher levels of lipidated LC3, indicating an induction of autophagy [57] . ./cache/cord-258536-qnn9hp8e.txt ./txt/cord-258536-qnn9hp8e.txt