id author title date pages extension mime words sentences flesch summary cache txt cord-003961-gs75ebo4 Yin, Xin Hepatitis E Virus Entry 2019-09-20 .txt text/plain 5141 261 47 The enteric route of transmission, EM evidence of naked virions in the feces, and the lack of coding capacity for envelope proteins all suggest that HEV is a nonenveloped virus. The enteric route of transmission, EM evidence of naked virions in the feces, and the lack of coding capacity for envelope proteins all suggest that HEV is a nonenveloped virus. However, recent studies show that the virus released from infected cells and circulating in the blood adopts a membrane associated, "quasienveloped" form, named "eHEV" [10, 11, 22] (Figure 1b ). However, recent studies show that the virus released from infected cells and circulating in the blood adopts a membrane associated, "quasienveloped" form, named "eHEV" [10, 11, 22] (Figure 1b ). The available evidence suggests that naked and quasienveloped HEV particles use different mechanisms for cell entry, and that entry of eHEV requires lysosomal degradation of the viral membrane. ORF3 protein of hepatitis E virus is essential for virion release from infected cells ./cache/cord-003961-gs75ebo4.txt ./txt/cord-003961-gs75ebo4.txt