id	sid	tid	token	lemma	pos
cord-293938-40zyv1h8	1	1	key	key	JJ
cord-293938-40zyv1h8	1	2	:	:	:
cord-293938-40zyv1h8	1	3	cord-293938	cord-293938	NNP
cord-293938-40zyv1h8	1	4	-	-	HYPH
cord-293938-40zyv1h8	1	5	40zyv1h8	40zyv1h8	CD
cord-293938-40zyv1h8	2	1	authors	author	NNS
cord-293938-40zyv1h8	2	2	:	:	:
cord-293938-40zyv1h8	2	3	Jonsdottir	Jonsdottir	NNP
cord-293938-40zyv1h8	2	4	,	,	,
cord-293938-40zyv1h8	2	5	Hulda	Hulda	NNP
cord-293938-40zyv1h8	2	6	R.	R.	NNP
cord-293938-40zyv1h8	2	7	;	;	:
cord-293938-40zyv1h8	2	8	Dijkman	Dijkman	NNP
cord-293938-40zyv1h8	2	9	,	,	,
cord-293938-40zyv1h8	2	10	Ronald	Ronald	NNP
cord-293938-40zyv1h8	2	11	title	title	NN
cord-293938-40zyv1h8	2	12	:	:	:
cord-293938-40zyv1h8	2	13	Coronaviruses	Coronaviruses	NNP
cord-293938-40zyv1h8	2	14	and	and	CC
cord-293938-40zyv1h8	2	15	the	the	DT
cord-293938-40zyv1h8	2	16	human	human	JJ
cord-293938-40zyv1h8	2	17	airway	airway	NN
cord-293938-40zyv1h8	2	18	:	:	:
cord-293938-40zyv1h8	2	19	a	a	DT
cord-293938-40zyv1h8	2	20	universal	universal	JJ
cord-293938-40zyv1h8	2	21	system	system	NN
cord-293938-40zyv1h8	2	22	for	for	IN
cord-293938-40zyv1h8	2	23	virus	virus	NN
cord-293938-40zyv1h8	2	24	-	-	HYPH
cord-293938-40zyv1h8	2	25	host	host	NN
cord-293938-40zyv1h8	2	26	interaction	interaction	NN
cord-293938-40zyv1h8	2	27	studies	study	NNS
cord-293938-40zyv1h8	2	28	date	date	NN
cord-293938-40zyv1h8	2	29	:	:	:
cord-293938-40zyv1h8	2	30	2016	2016	CD
cord-293938-40zyv1h8	2	31	-	-	HYPH
cord-293938-40zyv1h8	2	32	02	02	CD
cord-293938-40zyv1h8	2	33	-	-	HYPH
cord-293938-40zyv1h8	2	34	06	06	CD
cord-293938-40zyv1h8	2	35	journal	journal	NN
cord-293938-40zyv1h8	2	36	:	:	:
cord-293938-40zyv1h8	3	1	Virol	Virol	NNP
cord-293938-40zyv1h8	3	2	J	J	NNP
cord-293938-40zyv1h8	3	3	DOI	DOI	NNP
cord-293938-40zyv1h8	3	4	:	:	:
cord-293938-40zyv1h8	4	1	10.1186	10.1186	CD
cord-293938-40zyv1h8	4	2	/	/	SYM
cord-293938-40zyv1h8	4	3	s12985	s12985	NN
cord-293938-40zyv1h8	4	4	-	-	HYPH
cord-293938-40zyv1h8	4	5	016	016	CD
cord-293938-40zyv1h8	4	6	-	-	HYPH
cord-293938-40zyv1h8	4	7	0479	0479	CD
cord-293938-40zyv1h8	4	8	-	-	SYM
cord-293938-40zyv1h8	4	9	5	5	CD
cord-293938-40zyv1h8	4	10	sha	sha	NN
cord-293938-40zyv1h8	4	11	:	:	:
cord-293938-40zyv1h8	4	12	a1dde82e18ad108c7eedb452d50a661e647b7cf2	a1dde82e18ad108c7eedb452d50a661e647b7cf2	NNP
cord-293938-40zyv1h8	4	13	doc_id	doc_id	NNP
cord-293938-40zyv1h8	4	14	:	:	:
cord-293938-40zyv1h8	4	15	293938	293938	CD
cord-293938-40zyv1h8	4	16	cord_uid	cord_uid	FW
cord-293938-40zyv1h8	4	17	:	:	:
cord-293938-40zyv1h8	5	1	40zyv1h8	40zyv1h8	CD
cord-293938-40zyv1h8	5	2	Human	human	JJ
cord-293938-40zyv1h8	5	3	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	5	4	(	(	-LRB-
cord-293938-40zyv1h8	5	5	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	5	6	)	)	-RRB-
cord-293938-40zyv1h8	5	7	are	be	VBP
cord-293938-40zyv1h8	5	8	large	large	JJ
cord-293938-40zyv1h8	5	9	RNA	RNA	NNP
cord-293938-40zyv1h8	5	10	viruses	virus	NNS
cord-293938-40zyv1h8	5	11	that	that	WDT
cord-293938-40zyv1h8	5	12	infect	infect	VBP
cord-293938-40zyv1h8	5	13	the	the	DT
cord-293938-40zyv1h8	5	14	human	human	JJ
cord-293938-40zyv1h8	5	15	respiratory	respiratory	JJ
cord-293938-40zyv1h8	5	16	tract	tract	NN
cord-293938-40zyv1h8	5	17	.	.	.
cord-293938-40zyv1h8	6	1	The	the	DT
cord-293938-40zyv1h8	6	2	emergence	emergence	NN
cord-293938-40zyv1h8	6	3	of	of	IN
cord-293938-40zyv1h8	6	4	both	both	CC
cord-293938-40zyv1h8	6	5	Severe	severe	JJ
cord-293938-40zyv1h8	6	6	Acute	acute	JJ
cord-293938-40zyv1h8	6	7	Respiratory	Respiratory	NNP
cord-293938-40zyv1h8	6	8	Syndrome	Syndrome	NNP
cord-293938-40zyv1h8	6	9	and	and	CC
cord-293938-40zyv1h8	6	10	Middle	Middle	NNP
cord-293938-40zyv1h8	6	11	East	East	NNP
cord-293938-40zyv1h8	6	12	Respiratory	respiratory	JJ
cord-293938-40zyv1h8	6	13	syndrome	syndrome	NN
cord-293938-40zyv1h8	6	14	CoVs	CoVs	NNP
cord-293938-40zyv1h8	6	15	as	as	RB
cord-293938-40zyv1h8	6	16	well	well	RB
cord-293938-40zyv1h8	6	17	as	as	IN
cord-293938-40zyv1h8	6	18	the	the	DT
cord-293938-40zyv1h8	6	19	yearly	yearly	JJ
cord-293938-40zyv1h8	6	20	circulation	circulation	NN
cord-293938-40zyv1h8	6	21	of	of	IN
cord-293938-40zyv1h8	6	22	four	four	CD
cord-293938-40zyv1h8	6	23	common	common	JJ
cord-293938-40zyv1h8	6	24	CoVs	CoVs	NNP
cord-293938-40zyv1h8	6	25	highlights	highlight	VBZ
cord-293938-40zyv1h8	6	26	the	the	DT
cord-293938-40zyv1h8	6	27	importance	importance	NN
cord-293938-40zyv1h8	6	28	of	of	IN
cord-293938-40zyv1h8	6	29	elucidating	elucidate	VBG
cord-293938-40zyv1h8	6	30	the	the	DT
cord-293938-40zyv1h8	6	31	different	different	JJ
cord-293938-40zyv1h8	6	32	mechanisms	mechanism	NNS
cord-293938-40zyv1h8	6	33	employed	employ	VBN
cord-293938-40zyv1h8	6	34	by	by	IN
cord-293938-40zyv1h8	6	35	these	these	DT
cord-293938-40zyv1h8	6	36	viruses	virus	NNS
cord-293938-40zyv1h8	6	37	to	to	TO
cord-293938-40zyv1h8	6	38	evade	evade	VB
cord-293938-40zyv1h8	6	39	the	the	DT
cord-293938-40zyv1h8	6	40	host	host	NN
cord-293938-40zyv1h8	6	41	immune	immune	JJ
cord-293938-40zyv1h8	6	42	response	response	NN
cord-293938-40zyv1h8	6	43	,	,	,
cord-293938-40zyv1h8	6	44	determine	determine	VB
cord-293938-40zyv1h8	6	45	their	-PRON-	PRP$
cord-293938-40zyv1h8	6	46	tropism	tropism	NN
cord-293938-40zyv1h8	6	47	and	and	CC
cord-293938-40zyv1h8	6	48	identify	identify	VB
cord-293938-40zyv1h8	6	49	antiviral	antiviral	JJ
cord-293938-40zyv1h8	6	50	compounds	compound	NNS
cord-293938-40zyv1h8	6	51	.	.	.
cord-293938-40zyv1h8	7	1	Various	various	JJ
cord-293938-40zyv1h8	7	2	animal	animal	NN
cord-293938-40zyv1h8	7	3	models	model	NNS
cord-293938-40zyv1h8	7	4	have	have	VBP
cord-293938-40zyv1h8	7	5	been	be	VBN
cord-293938-40zyv1h8	7	6	established	establish	VBN
cord-293938-40zyv1h8	7	7	to	to	TO
cord-293938-40zyv1h8	7	8	investigate	investigate	VB
cord-293938-40zyv1h8	7	9	HCoV	HCoV	NNP
cord-293938-40zyv1h8	7	10	infection	infection	NN
cord-293938-40zyv1h8	7	11	,	,	,
cord-293938-40zyv1h8	7	12	including	include	VBG
cord-293938-40zyv1h8	7	13	mice	mouse	NNS
cord-293938-40zyv1h8	7	14	and	and	CC
cord-293938-40zyv1h8	7	15	non	non	JJ
cord-293938-40zyv1h8	7	16	-	-	JJ
cord-293938-40zyv1h8	7	17	human	human	JJ
cord-293938-40zyv1h8	7	18	primates	primate	NNS
cord-293938-40zyv1h8	7	19	.	.	.
cord-293938-40zyv1h8	8	1	To	to	TO
cord-293938-40zyv1h8	8	2	establish	establish	VB
cord-293938-40zyv1h8	8	3	a	a	DT
cord-293938-40zyv1h8	8	4	link	link	NN
cord-293938-40zyv1h8	8	5	between	between	IN
cord-293938-40zyv1h8	8	6	the	the	DT
cord-293938-40zyv1h8	8	7	research	research	NN
cord-293938-40zyv1h8	8	8	conducted	conduct	VBN
cord-293938-40zyv1h8	8	9	in	in	IN
cord-293938-40zyv1h8	8	10	animal	animal	NN
cord-293938-40zyv1h8	8	11	models	model	NNS
cord-293938-40zyv1h8	8	12	and	and	CC
cord-293938-40zyv1h8	8	13	humans	human	NNS
cord-293938-40zyv1h8	8	14	,	,	,
cord-293938-40zyv1h8	8	15	an	an	DT
cord-293938-40zyv1h8	8	16	organotypic	organotypic	JJ
cord-293938-40zyv1h8	8	17	human	human	JJ
cord-293938-40zyv1h8	8	18	airway	airway	NN
cord-293938-40zyv1h8	8	19	culture	culture	NN
cord-293938-40zyv1h8	8	20	system	system	NN
cord-293938-40zyv1h8	8	21	,	,	,
cord-293938-40zyv1h8	8	22	that	that	WDT
cord-293938-40zyv1h8	8	23	recapitulates	recapitulate	VBZ
cord-293938-40zyv1h8	8	24	the	the	DT
cord-293938-40zyv1h8	8	25	human	human	JJ
cord-293938-40zyv1h8	8	26	airway	airway	NN
cord-293938-40zyv1h8	8	27	epithelium	epithelium	NN
cord-293938-40zyv1h8	8	28	,	,	,
cord-293938-40zyv1h8	8	29	has	have	VBZ
cord-293938-40zyv1h8	8	30	been	be	VBN
cord-293938-40zyv1h8	8	31	developed	develop	VBN
cord-293938-40zyv1h8	8	32	.	.	.
cord-293938-40zyv1h8	9	1	Currently	currently	RB
cord-293938-40zyv1h8	9	2	,	,	,
cord-293938-40zyv1h8	9	3	different	different	JJ
cord-293938-40zyv1h8	9	4	cell	cell	NN
cord-293938-40zyv1h8	9	5	culture	culture	NN
cord-293938-40zyv1h8	9	6	systems	system	NNS
cord-293938-40zyv1h8	9	7	are	be	VBP
cord-293938-40zyv1h8	9	8	available	available	JJ
cord-293938-40zyv1h8	9	9	to	to	TO
cord-293938-40zyv1h8	9	10	recapitulate	recapitulate	VB
cord-293938-40zyv1h8	9	11	the	the	DT
cord-293938-40zyv1h8	9	12	human	human	NNP
cord-293938-40zyv1h8	9	13	airways	airway	NNS
cord-293938-40zyv1h8	9	14	,	,	,
cord-293938-40zyv1h8	9	15	including	include	VBG
cord-293938-40zyv1h8	9	16	the	the	DT
cord-293938-40zyv1h8	9	17	Air	Air	NNP
cord-293938-40zyv1h8	9	18	-	-	HYPH
cord-293938-40zyv1h8	9	19	Liquid	Liquid	NNP
cord-293938-40zyv1h8	9	20	Interface	interface	NN
cord-293938-40zyv1h8	9	21	(	(	-LRB-
cord-293938-40zyv1h8	9	22	ALI	ALI	NNP
cord-293938-40zyv1h8	9	23	)	)	-RRB-
cord-293938-40zyv1h8	9	24	human	human	JJ
cord-293938-40zyv1h8	9	25	airway	airway	NN
cord-293938-40zyv1h8	9	26	epithelium	epithelium	NN
cord-293938-40zyv1h8	9	27	(	(	-LRB-
cord-293938-40zyv1h8	9	28	HAE	HAE	NNP
cord-293938-40zyv1h8	9	29	)	)	-RRB-
cord-293938-40zyv1h8	9	30	model	model	NN
cord-293938-40zyv1h8	9	31	.	.	.
cord-293938-40zyv1h8	10	1	Tracheobronchial	Tracheobronchial	NNP
cord-293938-40zyv1h8	10	2	HAE	HAE	NNP
cord-293938-40zyv1h8	10	3	cultures	culture	NNS
cord-293938-40zyv1h8	10	4	recapitulate	recapitulate	VBP
cord-293938-40zyv1h8	10	5	the	the	DT
cord-293938-40zyv1h8	10	6	primary	primary	JJ
cord-293938-40zyv1h8	10	7	entry	entry	NN
cord-293938-40zyv1h8	10	8	point	point	NN
cord-293938-40zyv1h8	10	9	of	of	IN
cord-293938-40zyv1h8	10	10	human	human	JJ
cord-293938-40zyv1h8	10	11	respiratory	respiratory	JJ
cord-293938-40zyv1h8	10	12	viruses	virus	NNS
cord-293938-40zyv1h8	10	13	while	while	IN
cord-293938-40zyv1h8	10	14	the	the	DT
cord-293938-40zyv1h8	10	15	alveolar	alveolar	NN
cord-293938-40zyv1h8	10	16	model	model	NN
cord-293938-40zyv1h8	10	17	allows	allow	VBZ
cord-293938-40zyv1h8	10	18	for	for	IN
cord-293938-40zyv1h8	10	19	elucidation	elucidation	NN
cord-293938-40zyv1h8	10	20	of	of	IN
cord-293938-40zyv1h8	10	21	mechanisms	mechanism	NNS
cord-293938-40zyv1h8	10	22	involved	involve	VBN
cord-293938-40zyv1h8	10	23	in	in	IN
cord-293938-40zyv1h8	10	24	viral	viral	JJ
cord-293938-40zyv1h8	10	25	infection	infection	NN
cord-293938-40zyv1h8	10	26	and	and	CC
cord-293938-40zyv1h8	10	27	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	10	28	in	in	IN
cord-293938-40zyv1h8	10	29	the	the	DT
cord-293938-40zyv1h8	10	30	alveoli	alveolus	NNS
cord-293938-40zyv1h8	10	31	.	.	.
cord-293938-40zyv1h8	11	1	These	these	DT
cord-293938-40zyv1h8	11	2	organotypic	organotypic	JJ
cord-293938-40zyv1h8	11	3	human	human	JJ
cord-293938-40zyv1h8	11	4	airway	airway	NN
cord-293938-40zyv1h8	11	5	cultures	culture	NNS
cord-293938-40zyv1h8	11	6	represent	represent	VBP
cord-293938-40zyv1h8	11	7	a	a	DT
cord-293938-40zyv1h8	11	8	universal	universal	JJ
cord-293938-40zyv1h8	11	9	platform	platform	NN
cord-293938-40zyv1h8	11	10	to	to	TO
cord-293938-40zyv1h8	11	11	study	study	VB
cord-293938-40zyv1h8	11	12	respiratory	respiratory	JJ
cord-293938-40zyv1h8	11	13	virus	virus	NN
cord-293938-40zyv1h8	11	14	-	-	HYPH
cord-293938-40zyv1h8	11	15	host	host	NN
cord-293938-40zyv1h8	11	16	interaction	interaction	NN
cord-293938-40zyv1h8	11	17	by	by	IN
cord-293938-40zyv1h8	11	18	offering	offer	VBG
cord-293938-40zyv1h8	11	19	more	more	RBR
cord-293938-40zyv1h8	11	20	detailed	detailed	JJ
cord-293938-40zyv1h8	11	21	insights	insight	NNS
cord-293938-40zyv1h8	11	22	compared	compare	VBN
cord-293938-40zyv1h8	11	23	to	to	IN
cord-293938-40zyv1h8	11	24	cell	cell	NN
cord-293938-40zyv1h8	11	25	lines	line	NNS
cord-293938-40zyv1h8	11	26	.	.	.
cord-293938-40zyv1h8	12	1	Additionally	additionally	RB
cord-293938-40zyv1h8	12	2	,	,	,
cord-293938-40zyv1h8	12	3	the	the	DT
cord-293938-40zyv1h8	12	4	epidemic	epidemic	NN
cord-293938-40zyv1h8	12	5	potential	potential	NN
cord-293938-40zyv1h8	12	6	of	of	IN
cord-293938-40zyv1h8	12	7	this	this	DT
cord-293938-40zyv1h8	12	8	virus	virus	NN
cord-293938-40zyv1h8	12	9	family	family	NN
cord-293938-40zyv1h8	12	10	highlights	highlight	VBZ
cord-293938-40zyv1h8	12	11	the	the	DT
cord-293938-40zyv1h8	12	12	need	need	NN
cord-293938-40zyv1h8	12	13	for	for	IN
cord-293938-40zyv1h8	12	14	both	both	DT
cord-293938-40zyv1h8	12	15	vaccines	vaccine	NNS
cord-293938-40zyv1h8	12	16	and	and	CC
cord-293938-40zyv1h8	12	17	antivirals	antiviral	NNS
cord-293938-40zyv1h8	12	18	.	.	.
cord-293938-40zyv1h8	13	1	No	no	DT
cord-293938-40zyv1h8	13	2	commercial	commercial	JJ
cord-293938-40zyv1h8	13	3	vaccine	vaccine	NN
cord-293938-40zyv1h8	13	4	is	be	VBZ
cord-293938-40zyv1h8	13	5	available	available	JJ
cord-293938-40zyv1h8	13	6	but	but	CC
cord-293938-40zyv1h8	13	7	various	various	JJ
cord-293938-40zyv1h8	13	8	effective	effective	JJ
cord-293938-40zyv1h8	13	9	antivirals	antiviral	NNS
cord-293938-40zyv1h8	13	10	have	have	VBP
cord-293938-40zyv1h8	13	11	been	be	VBN
cord-293938-40zyv1h8	13	12	identified	identify	VBN
cord-293938-40zyv1h8	13	13	,	,	,
cord-293938-40zyv1h8	13	14	some	some	DT
cord-293938-40zyv1h8	13	15	with	with	IN
cord-293938-40zyv1h8	13	16	potential	potential	NN
cord-293938-40zyv1h8	13	17	for	for	IN
cord-293938-40zyv1h8	13	18	human	human	JJ
cord-293938-40zyv1h8	13	19	treatment	treatment	NN
cord-293938-40zyv1h8	13	20	.	.	.
cord-293938-40zyv1h8	14	1	These	these	DT
cord-293938-40zyv1h8	14	2	morphological	morphological	JJ
cord-293938-40zyv1h8	14	3	airway	airway	NN
cord-293938-40zyv1h8	14	4	cultures	culture	NNS
cord-293938-40zyv1h8	14	5	are	be	VBP
cord-293938-40zyv1h8	14	6	also	also	RB
cord-293938-40zyv1h8	14	7	well	well	RB
cord-293938-40zyv1h8	14	8	suited	suited	JJ
cord-293938-40zyv1h8	14	9	for	for	IN
cord-293938-40zyv1h8	14	10	the	the	DT
cord-293938-40zyv1h8	14	11	identification	identification	NN
cord-293938-40zyv1h8	14	12	of	of	IN
cord-293938-40zyv1h8	14	13	antivirals	antiviral	NNS
cord-293938-40zyv1h8	14	14	,	,	,
cord-293938-40zyv1h8	14	15	evaluation	evaluation	NN
cord-293938-40zyv1h8	14	16	of	of	IN
cord-293938-40zyv1h8	14	17	compound	compound	NN
cord-293938-40zyv1h8	14	18	toxicity	toxicity	NN
cord-293938-40zyv1h8	14	19	and	and	CC
cord-293938-40zyv1h8	14	20	viral	viral	JJ
cord-293938-40zyv1h8	14	21	inhibition	inhibition	NN
cord-293938-40zyv1h8	14	22	.	.	.
cord-293938-40zyv1h8	15	1	Respiratory	respiratory	JJ
cord-293938-40zyv1h8	15	2	diseases	disease	NNS
cord-293938-40zyv1h8	15	3	caused	cause	VBN
cord-293938-40zyv1h8	15	4	by	by	IN
cord-293938-40zyv1h8	15	5	human	human	JJ
cord-293938-40zyv1h8	15	6	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	15	7	infection	infection	NN
cord-293938-40zyv1h8	15	8	are	be	VBP
cord-293938-40zyv1h8	15	9	of	of	IN
cord-293938-40zyv1h8	15	10	both	both	CC
cord-293938-40zyv1h8	15	11	medical	medical	JJ
cord-293938-40zyv1h8	15	12	and	and	CC
cord-293938-40zyv1h8	15	13	socio	socio	JJ
cord-293938-40zyv1h8	15	14	-	-	HYPH
cord-293938-40zyv1h8	15	15	economic	economic	JJ
cord-293938-40zyv1h8	15	16	importance	importance	NN
cord-293938-40zyv1h8	15	17	.	.	.
cord-293938-40zyv1h8	16	1	Currently	currently	RB
cord-293938-40zyv1h8	16	2	,	,	,
cord-293938-40zyv1h8	16	3	they	-PRON-	PRP
cord-293938-40zyv1h8	16	4	are	be	VBP
cord-293938-40zyv1h8	16	5	studied	study	VBN
cord-293938-40zyv1h8	16	6	in	in	IN
cord-293938-40zyv1h8	16	7	various	various	JJ
cord-293938-40zyv1h8	16	8	model	model	NN
cord-293938-40zyv1h8	16	9	systems	system	NNS
cord-293938-40zyv1h8	16	10	,	,	,
cord-293938-40zyv1h8	16	11	ranging	range	VBG
cord-293938-40zyv1h8	16	12	from	from	IN
cord-293938-40zyv1h8	16	13	cell	cell	NN
cord-293938-40zyv1h8	16	14	lines	line	NNS
cord-293938-40zyv1h8	16	15	to	to	IN
cord-293938-40zyv1h8	16	16	animal	animal	NN
cord-293938-40zyv1h8	16	17	models	model	NNS
cord-293938-40zyv1h8	16	18	.	.	.
cord-293938-40zyv1h8	17	1	Originally	originally	RB
cord-293938-40zyv1h8	17	2	,	,	,
cord-293938-40zyv1h8	17	3	the	the	DT
cord-293938-40zyv1h8	17	4	importance	importance	NN
cord-293938-40zyv1h8	17	5	of	of	IN
cord-293938-40zyv1h8	17	6	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	17	7	in	in	IN
cord-293938-40zyv1h8	17	8	the	the	DT
cord-293938-40zyv1h8	17	9	burden	burden	NN
cord-293938-40zyv1h8	17	10	of	of	IN
cord-293938-40zyv1h8	17	11	human	human	JJ
cord-293938-40zyv1h8	17	12	disease	disease	NN
cord-293938-40zyv1h8	17	13	was	be	VBD
cord-293938-40zyv1h8	17	14	underestimated	underestimate	VBN
cord-293938-40zyv1h8	17	15	and	and	CC
cord-293938-40zyv1h8	17	16	as	as	IN
cord-293938-40zyv1h8	17	17	a	a	DT
cord-293938-40zyv1h8	17	18	result	result	NN
cord-293938-40zyv1h8	17	19	,	,	,
cord-293938-40zyv1h8	17	20	no	no	DT
cord-293938-40zyv1h8	17	21	general	general	JJ
cord-293938-40zyv1h8	17	22	therapy	therapy	NN
cord-293938-40zyv1h8	17	23	exists	exist	VBZ
cord-293938-40zyv1h8	17	24	to	to	TO
cord-293938-40zyv1h8	17	25	treat	treat	VB
cord-293938-40zyv1h8	17	26	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	17	27	induced	induce	VBN
cord-293938-40zyv1h8	17	28	disease	disease	NN
cord-293938-40zyv1h8	17	29	in	in	IN
cord-293938-40zyv1h8	17	30	humans	human	NNS
cord-293938-40zyv1h8	17	31	.	.	.
cord-293938-40zyv1h8	18	1	Furthermore	furthermore	RB
cord-293938-40zyv1h8	18	2	,	,	,
cord-293938-40zyv1h8	18	3	no	no	DT
cord-293938-40zyv1h8	18	4	commercial	commercial	JJ
cord-293938-40zyv1h8	18	5	vaccine	vaccine	NN
cord-293938-40zyv1h8	18	6	is	be	VBZ
cord-293938-40zyv1h8	18	7	available	available	JJ
cord-293938-40zyv1h8	18	8	leaving	leave	VBG
cord-293938-40zyv1h8	18	9	the	the	DT
cord-293938-40zyv1h8	18	10	human	human	JJ
cord-293938-40zyv1h8	18	11	population	population	NN
cord-293938-40zyv1h8	18	12	vulnerable	vulnerable	JJ
cord-293938-40zyv1h8	18	13	to	to	IN
cord-293938-40zyv1h8	18	14	emerging	emerge	VBG
cord-293938-40zyv1h8	18	15	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	18	16	infections	infection	NNS
cord-293938-40zyv1h8	18	17	.	.	.
cord-293938-40zyv1h8	19	1	Both	both	DT
cord-293938-40zyv1h8	19	2	the	the	DT
cord-293938-40zyv1h8	19	3	Severe	severe	JJ
cord-293938-40zyv1h8	19	4	Acute	acute	JJ
cord-293938-40zyv1h8	19	5	Respiratory	Respiratory	NNP
cord-293938-40zyv1h8	19	6	Syndrome	Syndrome	NNP
cord-293938-40zyv1h8	19	7	and	and	CC
cord-293938-40zyv1h8	19	8	Middle	Middle	NNP
cord-293938-40zyv1h8	19	9	East	East	NNP
cord-293938-40zyv1h8	19	10	Respiratory	Respiratory	NNP
cord-293938-40zyv1h8	19	11	Syndrome	Syndrome	NNP
cord-293938-40zyv1h8	19	12	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	19	13	have	have	VBP
cord-293938-40zyv1h8	19	14	recently	recently	RB
cord-293938-40zyv1h8	19	15	crossed	cross	VBN
cord-293938-40zyv1h8	19	16	the	the	DT
cord-293938-40zyv1h8	19	17	species	specie	NNS
cord-293938-40zyv1h8	19	18	barrier	barrier	NN
cord-293938-40zyv1h8	19	19	and	and	CC
cord-293938-40zyv1h8	19	20	entered	enter	VBD
cord-293938-40zyv1h8	19	21	the	the	DT
cord-293938-40zyv1h8	19	22	human	human	JJ
cord-293938-40zyv1h8	19	23	population	population	NN
cord-293938-40zyv1h8	19	24	to	to	TO
cord-293938-40zyv1h8	19	25	cause	cause	VB
cord-293938-40zyv1h8	19	26	severe	severe	JJ
cord-293938-40zyv1h8	19	27	disease	disease	NN
cord-293938-40zyv1h8	19	28	.	.	.
cord-293938-40zyv1h8	20	1	In	in	IN
cord-293938-40zyv1h8	20	2	this	this	DT
cord-293938-40zyv1h8	20	3	review	review	NN
cord-293938-40zyv1h8	20	4	,	,	,
cord-293938-40zyv1h8	20	5	we	-PRON-	PRP
cord-293938-40zyv1h8	20	6	summarize	summarize	VBP
cord-293938-40zyv1h8	20	7	the	the	DT
cord-293938-40zyv1h8	20	8	current	current	JJ
cord-293938-40zyv1h8	20	9	knowledge	knowledge	NN
cord-293938-40zyv1h8	20	10	on	on	IN
cord-293938-40zyv1h8	20	11	human	human	JJ
cord-293938-40zyv1h8	20	12	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	20	13	infection	infection	NN
cord-293938-40zyv1h8	20	14	emphasizing	emphasize	VBG
cord-293938-40zyv1h8	20	15	the	the	DT
cord-293938-40zyv1h8	20	16	usefulness	usefulness	NN
cord-293938-40zyv1h8	20	17	of	of	IN
cord-293938-40zyv1h8	20	18	organotypic	organotypic	JJ
cord-293938-40zyv1h8	20	19	human	human	JJ
cord-293938-40zyv1h8	20	20	airway	airway	NN
cord-293938-40zyv1h8	20	21	cultures	culture	NNS
cord-293938-40zyv1h8	20	22	as	as	IN
cord-293938-40zyv1h8	20	23	a	a	DT
cord-293938-40zyv1h8	20	24	model	model	NN
cord-293938-40zyv1h8	20	25	system	system	NN
cord-293938-40zyv1h8	20	26	.	.	.
cord-293938-40zyv1h8	21	1	Coronaviruses	Coronaviruses	NNP
cord-293938-40zyv1h8	21	2	(	(	-LRB-
cord-293938-40zyv1h8	21	3	CoVs	CoVs	NNP
cord-293938-40zyv1h8	21	4	)	)	-RRB-
cord-293938-40zyv1h8	21	5	,	,	,
cord-293938-40zyv1h8	21	6	a	a	DT
cord-293938-40zyv1h8	21	7	subfamily	subfamily	NN
cord-293938-40zyv1h8	21	8	of	of	IN
cord-293938-40zyv1h8	21	9	the	the	DT
cord-293938-40zyv1h8	21	10	Coronaviridae	Coronaviridae	NNP
cord-293938-40zyv1h8	21	11	family	family	NN
cord-293938-40zyv1h8	21	12	,	,	,
cord-293938-40zyv1h8	21	13	are	be	VBP
cord-293938-40zyv1h8	21	14	positive	positive	JJ
cord-293938-40zyv1h8	21	15	strand	strand	NN
cord-293938-40zyv1h8	21	16	RNA	rna	NN
cord-293938-40zyv1h8	21	17	viruses	virus	NNS
cord-293938-40zyv1h8	21	18	with	with	IN
cord-293938-40zyv1h8	21	19	the	the	DT
cord-293938-40zyv1h8	21	20	largest	large	JJS
cord-293938-40zyv1h8	21	21	genome	genome	NN
cord-293938-40zyv1h8	21	22	of	of	IN
cord-293938-40zyv1h8	21	23	all	all	DT
cord-293938-40zyv1h8	21	24	known	know	VBN
cord-293938-40zyv1h8	21	25	RNA	rna	NN
cord-293938-40zyv1h8	21	26	viruses	virus	NNS
cord-293938-40zyv1h8	21	27	(	(	-LRB-
cord-293938-40zyv1h8	21	28	≥27	≥27	IN
cord-293938-40zyv1h8	21	29	Kb	Kb	NNP
cord-293938-40zyv1h8	21	30	)	)	-RRB-
cord-293938-40zyv1h8	21	31	.	.	.
cord-293938-40zyv1h8	22	1	The	the	DT
cord-293938-40zyv1h8	22	2	genomic	genomic	JJ
cord-293938-40zyv1h8	22	3	RNA	rna	NN
cord-293938-40zyv1h8	22	4	is	be	VBZ
cord-293938-40zyv1h8	22	5	capped	cap	VBN
cord-293938-40zyv1h8	22	6	,	,	,
cord-293938-40zyv1h8	22	7	polyadenylated	polyadenylated	JJ
cord-293938-40zyv1h8	22	8	and	and	CC
cord-293938-40zyv1h8	22	9	associated	associate	VBN
cord-293938-40zyv1h8	22	10	with	with	IN
cord-293938-40zyv1h8	22	11	nucleocapsid	nucleocapsid	NN
cord-293938-40zyv1h8	22	12	proteins	protein	NNS
cord-293938-40zyv1h8	22	13	within	within	IN
cord-293938-40zyv1h8	22	14	an	an	DT
cord-293938-40zyv1h8	22	15	enveloped	envelop	VBN
cord-293938-40zyv1h8	22	16	virion	virion	NN
cord-293938-40zyv1h8	22	17	.	.	.
cord-293938-40zyv1h8	23	1	The	the	DT
cord-293938-40zyv1h8	23	2	envelope	envelope	NN
cord-293938-40zyv1h8	23	3	is	be	VBZ
cord-293938-40zyv1h8	23	4	covered	cover	VBN
cord-293938-40zyv1h8	23	5	by	by	IN
cord-293938-40zyv1h8	23	6	the	the	DT
cord-293938-40zyv1h8	23	7	characteristic	characteristic	JJ
cord-293938-40zyv1h8	23	8	surface	surface	NN
cord-293938-40zyv1h8	23	9	glycoprotein	glycoprotein	NN
cord-293938-40zyv1h8	23	10	that	that	WDT
cord-293938-40zyv1h8	23	11	gives	give	VBZ
cord-293938-40zyv1h8	23	12	the	the	DT
cord-293938-40zyv1h8	23	13	virus	virus	NN
cord-293938-40zyv1h8	23	14	particles	particle	VBZ
cord-293938-40zyv1h8	23	15	their	-PRON-	PRP$
cord-293938-40zyv1h8	23	16	characteristic	characteristic	JJ
cord-293938-40zyv1h8	23	17	crown	crown	NN
cord-293938-40zyv1h8	23	18	-	-	HYPH
cord-293938-40zyv1h8	23	19	like	like	JJ
cord-293938-40zyv1h8	23	20	(	(	-LRB-
cord-293938-40zyv1h8	23	21	latin	latin	NNP
cord-293938-40zyv1h8	23	22	:	:	:
cord-293938-40zyv1h8	23	23	corona	corona	NN
cord-293938-40zyv1h8	23	24	)	)	-RRB-
cord-293938-40zyv1h8	23	25	appearance	appearance	NN
cord-293938-40zyv1h8	23	26	[	[	-LRB-
cord-293938-40zyv1h8	23	27	1	1	CD
cord-293938-40zyv1h8	23	28	]	]	-RRB-
cord-293938-40zyv1h8	23	29	.	.	.
cord-293938-40zyv1h8	24	1	All	all	DT
cord-293938-40zyv1h8	24	2	CoVs	CoVs	NNP
cord-293938-40zyv1h8	24	3	share	share	VBP
cord-293938-40zyv1h8	24	4	a	a	DT
cord-293938-40zyv1h8	24	5	common	common	JJ
cord-293938-40zyv1h8	24	6	genome	genome	NN
cord-293938-40zyv1h8	24	7	organization	organization	NN
cord-293938-40zyv1h8	24	8	where	where	WRB
cord-293938-40zyv1h8	24	9	the	the	DT
cord-293938-40zyv1h8	24	10	replicase	replicase	NNP
cord-293938-40zyv1h8	24	11	gene	gene	NN
cord-293938-40zyv1h8	24	12	encompasses	encompass	VBZ
cord-293938-40zyv1h8	24	13	the	the	DT
cord-293938-40zyv1h8	24	14	5′-two	5′-two	CD
cord-293938-40zyv1h8	24	15	thirds	third	NNS
cord-293938-40zyv1h8	24	16	of	of	IN
cord-293938-40zyv1h8	24	17	the	the	DT
cord-293938-40zyv1h8	24	18	genome	genome	NN
cord-293938-40zyv1h8	24	19	and	and	CC
cord-293938-40zyv1h8	24	20	is	be	VBZ
cord-293938-40zyv1h8	24	21	comprised	comprise	VBN
cord-293938-40zyv1h8	24	22	of	of	IN
cord-293938-40zyv1h8	24	23	two	two	CD
cord-293938-40zyv1h8	24	24	overlapping	overlap	VBG
cord-293938-40zyv1h8	24	25	open	open	JJ
cord-293938-40zyv1h8	24	26	reading	reading	NN
cord-293938-40zyv1h8	24	27	frames	frame	NNS
cord-293938-40zyv1h8	24	28	(	(	-LRB-
cord-293938-40zyv1h8	24	29	ORFs	ORFs	NNP
cord-293938-40zyv1h8	24	30	)	)	-RRB-
cord-293938-40zyv1h8	24	31	,	,	,
cord-293938-40zyv1h8	24	32	ORF1a	ORF1a	NNP
cord-293938-40zyv1h8	24	33	and	and	CC
cord-293938-40zyv1h8	24	34	ORF1b	ORF1b	NNP
cord-293938-40zyv1h8	24	35	that	that	WDT
cord-293938-40zyv1h8	24	36	encode	encode	VBP
cord-293938-40zyv1h8	24	37	for	for	IN
cord-293938-40zyv1h8	24	38	up	up	IN
cord-293938-40zyv1h8	24	39	to	to	TO
cord-293938-40zyv1h8	24	40	16	16	CD
cord-293938-40zyv1h8	24	41	non	non	JJ
cord-293938-40zyv1h8	24	42	-	-	JJ
cord-293938-40zyv1h8	24	43	structural	structural	JJ
cord-293938-40zyv1h8	24	44	proteins	protein	NNS
cord-293938-40zyv1h8	24	45	.	.	.
cord-293938-40zyv1h8	25	1	The	the	DT
cord-293938-40zyv1h8	25	2	structural	structural	JJ
cord-293938-40zyv1h8	25	3	gene	gene	NN
cord-293938-40zyv1h8	25	4	region	region	NN
cord-293938-40zyv1h8	25	5	,	,	,
cord-293938-40zyv1h8	25	6	which	which	WDT
cord-293938-40zyv1h8	25	7	covers	cover	VBZ
cord-293938-40zyv1h8	25	8	the	the	DT
cord-293938-40zyv1h8	25	9	3′-third	3′-third	CD
cord-293938-40zyv1h8	25	10	of	of	IN
cord-293938-40zyv1h8	25	11	the	the	DT
cord-293938-40zyv1h8	25	12	genome	genome	NN
cord-293938-40zyv1h8	25	13	,	,	,
cord-293938-40zyv1h8	25	14	encodes	encode	VBZ
cord-293938-40zyv1h8	25	15	the	the	DT
cord-293938-40zyv1h8	25	16	canonical	canonical	JJ
cord-293938-40zyv1h8	25	17	set	set	NN
cord-293938-40zyv1h8	25	18	of	of	IN
cord-293938-40zyv1h8	25	19	structural	structural	JJ
cord-293938-40zyv1h8	25	20	protein	protein	NN
cord-293938-40zyv1h8	25	21	genes	gene	NNS
cord-293938-40zyv1h8	25	22	in	in	IN
cord-293938-40zyv1h8	25	23	the	the	DT
cord-293938-40zyv1h8	25	24	order	order	NN
cord-293938-40zyv1h8	25	25	5′	5′	CD
cord-293938-40zyv1h8	25	26	-spike	-spike	.
cord-293938-40zyv1h8	25	27	(	(	-LRB-
cord-293938-40zyv1h8	25	28	S	s	NN
cord-293938-40zyv1h8	25	29	)	)	-RRB-
cord-293938-40zyv1h8	26	1	-envelope	-envelope	:
cord-293938-40zyv1h8	27	1	(	(	-LRB-
cord-293938-40zyv1h8	27	2	E	e	NN
cord-293938-40zyv1h8	27	3	)	)	-RRB-
cord-293938-40zyv1h8	27	4	-membrane	-membrane	ADD
cord-293938-40zyv1h8	28	1	(	(	-LRB-
cord-293938-40zyv1h8	28	2	M	M	NNP
cord-293938-40zyv1h8	28	3	)	)	-RRB-
cord-293938-40zyv1h8	28	4	and	and	CC
cord-293938-40zyv1h8	28	5	nucleocapsid	nucleocapsid	NN
cord-293938-40zyv1h8	28	6	(	(	-LRB-
cord-293938-40zyv1h8	28	7	N	n	NN
cord-293938-40zyv1h8	28	8	)	)	-RRB-
cord-293938-40zyv1h8	29	1	-3′.	-3′.	.
cord-293938-40zyv1h8	30	1	The	the	DT
cord-293938-40zyv1h8	30	2	structural	structural	JJ
cord-293938-40zyv1h8	30	3	gene	gene	NN
cord-293938-40zyv1h8	30	4	region	region	NN
cord-293938-40zyv1h8	30	5	also	also	RB
cord-293938-40zyv1h8	30	6	harbors	harbor	VBZ
cord-293938-40zyv1h8	30	7	several	several	JJ
cord-293938-40zyv1h8	30	8	ORFs	orf	NNS
cord-293938-40zyv1h8	30	9	that	that	WDT
cord-293938-40zyv1h8	30	10	are	be	VBP
cord-293938-40zyv1h8	30	11	interspersed	intersperse	VBN
cord-293938-40zyv1h8	30	12	along	along	IN
cord-293938-40zyv1h8	30	13	the	the	DT
cord-293938-40zyv1h8	30	14	structural	structural	JJ
cord-293938-40zyv1h8	30	15	protein	protein	NN
cord-293938-40zyv1h8	30	16	coding	code	VBG
cord-293938-40zyv1h8	30	17	genes	gene	NNS
cord-293938-40zyv1h8	30	18	.	.	.
cord-293938-40zyv1h8	31	1	The	the	DT
cord-293938-40zyv1h8	31	2	number	number	NN
cord-293938-40zyv1h8	31	3	and	and	CC
cord-293938-40zyv1h8	31	4	location	location	NN
cord-293938-40zyv1h8	31	5	of	of	IN
cord-293938-40zyv1h8	31	6	these	these	DT
cord-293938-40zyv1h8	31	7	accessory	accessory	NN
cord-293938-40zyv1h8	31	8	ORFs	orfs	NN
cord-293938-40zyv1h8	31	9	vary	vary	VBP
cord-293938-40zyv1h8	31	10	between	between	IN
cord-293938-40zyv1h8	31	11	the	the	DT
cord-293938-40zyv1h8	31	12	CoV	cov	NN
cord-293938-40zyv1h8	31	13	species	specie	NNS
cord-293938-40zyv1h8	31	14	[	[	-LRB-
cord-293938-40zyv1h8	31	15	2	2	CD
cord-293938-40zyv1h8	31	16	,	,	,
cord-293938-40zyv1h8	31	17	3	3	CD
cord-293938-40zyv1h8	31	18	]	]	-RRB-
cord-293938-40zyv1h8	31	19	.	.	.
cord-293938-40zyv1h8	32	1	In	in	IN
cord-293938-40zyv1h8	32	2	animals	animal	NNS
cord-293938-40zyv1h8	32	3	,	,	,
cord-293938-40zyv1h8	32	4	CoV	cov	NN
cord-293938-40zyv1h8	32	5	infections	infection	NNS
cord-293938-40zyv1h8	32	6	are	be	VBP
cord-293938-40zyv1h8	32	7	mainly	mainly	RB
cord-293938-40zyv1h8	32	8	associated	associate	VBN
cord-293938-40zyv1h8	32	9	with	with	IN
cord-293938-40zyv1h8	32	10	respiratory	respiratory	JJ
cord-293938-40zyv1h8	32	11	and	and	CC
cord-293938-40zyv1h8	32	12	enteric	enteric	JJ
cord-293938-40zyv1h8	32	13	disease	disease	NN
cord-293938-40zyv1h8	32	14	and	and	CC
cord-293938-40zyv1h8	32	15	can	can	MD
cord-293938-40zyv1h8	32	16	have	have	VB
cord-293938-40zyv1h8	32	17	large	large	JJ
cord-293938-40zyv1h8	32	18	economical	economical	JJ
cord-293938-40zyv1h8	32	19	impact	impact	NN
cord-293938-40zyv1h8	32	20	on	on	IN
cord-293938-40zyv1h8	32	21	the	the	DT
cord-293938-40zyv1h8	32	22	veterinary	veterinary	JJ
cord-293938-40zyv1h8	32	23	industry	industry	NN
cord-293938-40zyv1h8	32	24	,	,	,
cord-293938-40zyv1h8	32	25	e.g.	e.g.	IN
cord-293938-40zyv1h8	32	26	Porcine	Porcine	NNP
cord-293938-40zyv1h8	32	27	Epidemic	Epidemic	NNP
cord-293938-40zyv1h8	32	28	Diarrhea	diarrhea	NN
cord-293938-40zyv1h8	32	29	Virus	virus	NN
cord-293938-40zyv1h8	32	30	(	(	-LRB-
cord-293938-40zyv1h8	32	31	PEDV	PEDV	NNP
cord-293938-40zyv1h8	32	32	)	)	-RRB-
cord-293938-40zyv1h8	32	33	causes	cause	VBZ
cord-293938-40zyv1h8	32	34	gastrointestinal	gastrointestinal	JJ
cord-293938-40zyv1h8	32	35	disease	disease	NN
cord-293938-40zyv1h8	32	36	in	in	IN
cord-293938-40zyv1h8	32	37	pigs	pig	NNS
cord-293938-40zyv1h8	32	38	[	[	-LRB-
cord-293938-40zyv1h8	32	39	4	4	CD
cord-293938-40zyv1h8	32	40	]	]	-RRB-
cord-293938-40zyv1h8	33	1	,	,	,
cord-293938-40zyv1h8	33	2	Infectious	Infectious	NNP
cord-293938-40zyv1h8	33	3	Bronchitis	Bronchitis	NNP
cord-293938-40zyv1h8	33	4	Virus	Virus	NNP
cord-293938-40zyv1h8	33	5	(	(	-LRB-
cord-293938-40zyv1h8	33	6	IBV	IBV	NNP
cord-293938-40zyv1h8	33	7	)	)	-RRB-
cord-293938-40zyv1h8	33	8	causes	cause	VBZ
cord-293938-40zyv1h8	33	9	severe	severe	JJ
cord-293938-40zyv1h8	33	10	kidney	kidney	NN
cord-293938-40zyv1h8	33	11	and	and	CC
cord-293938-40zyv1h8	33	12	respiratory	respiratory	JJ
cord-293938-40zyv1h8	33	13	disease	disease	NN
cord-293938-40zyv1h8	33	14	in	in	IN
cord-293938-40zyv1h8	33	15	chicken	chicken	NN
cord-293938-40zyv1h8	33	16	[	[	-LRB-
cord-293938-40zyv1h8	33	17	5	5	CD
cord-293938-40zyv1h8	33	18	]	]	-RRB-
cord-293938-40zyv1h8	33	19	and	and	CC
cord-293938-40zyv1h8	33	20	Bovine	Bovine	NNP
cord-293938-40zyv1h8	33	21	Coronavirus	Coronavirus	NNP
cord-293938-40zyv1h8	33	22	(	(	-LRB-
cord-293938-40zyv1h8	33	23	BCoV	BCoV	NNP
cord-293938-40zyv1h8	33	24	)	)	-RRB-
cord-293938-40zyv1h8	33	25	causes	cause	VBZ
cord-293938-40zyv1h8	33	26	both	both	DT
cord-293938-40zyv1h8	33	27	respiratory	respiratory	JJ
cord-293938-40zyv1h8	33	28	disease	disease	NN
cord-293938-40zyv1h8	33	29	and	and	CC
cord-293938-40zyv1h8	33	30	diarrhea	diarrhea	NN
cord-293938-40zyv1h8	33	31	in	in	IN
cord-293938-40zyv1h8	33	32	cattle	cattle	NNS
cord-293938-40zyv1h8	33	33	[	[	-LRB-
cord-293938-40zyv1h8	33	34	6	6	CD
cord-293938-40zyv1h8	33	35	]	]	-RRB-
cord-293938-40zyv1h8	33	36	.	.	.
cord-293938-40zyv1h8	34	1	Additionally	additionally	RB
cord-293938-40zyv1h8	34	2	,	,	,
cord-293938-40zyv1h8	34	3	CoV	cov	NN
cord-293938-40zyv1h8	34	4	infections	infection	NNS
cord-293938-40zyv1h8	34	5	can	can	MD
cord-293938-40zyv1h8	34	6	have	have	VB
cord-293938-40zyv1h8	34	7	other	other	JJ
cord-293938-40zyv1h8	34	8	disease	disease	NN
cord-293938-40zyv1h8	34	9	manifestations	manifestation	NNS
cord-293938-40zyv1h8	34	10	,	,	,
cord-293938-40zyv1h8	34	11	such	such	JJ
cord-293938-40zyv1h8	34	12	as	as	IN
cord-293938-40zyv1h8	34	13	central	central	JJ
cord-293938-40zyv1h8	34	14	nervous	nervous	JJ
cord-293938-40zyv1h8	34	15	system	system	NN
cord-293938-40zyv1h8	34	16	(	(	-LRB-
cord-293938-40zyv1h8	34	17	CNS	CNS	NNP
cord-293938-40zyv1h8	34	18	)	)	-RRB-
cord-293938-40zyv1h8	34	19	involvement	involvement	NN
cord-293938-40zyv1h8	34	20	,	,	,
cord-293938-40zyv1h8	34	21	hepatitis	hepatitis	NN
cord-293938-40zyv1h8	34	22	and	and	CC
cord-293938-40zyv1h8	34	23	peritonitis	peritonitis	NN
cord-293938-40zyv1h8	34	24	[	[	-LRB-
cord-293938-40zyv1h8	34	25	7	7	CD
cord-293938-40zyv1h8	34	26	]	]	-RRB-
cord-293938-40zyv1h8	35	1	[	[	-LRB-
cord-293938-40zyv1h8	35	2	8	8	CD
cord-293938-40zyv1h8	35	3	]	]	-RRB-
cord-293938-40zyv1h8	35	4	[	[	-LRB-
cord-293938-40zyv1h8	35	5	9	9	CD
cord-293938-40zyv1h8	35	6	]	]	-RRB-
cord-293938-40zyv1h8	35	7	[	[	-LRB-
cord-293938-40zyv1h8	35	8	10	10	CD
cord-293938-40zyv1h8	35	9	]	]	-RRB-
cord-293938-40zyv1h8	35	10	.	.	.
cord-293938-40zyv1h8	36	1	In	in	IN
cord-293938-40zyv1h8	36	2	humans	human	NNS
cord-293938-40zyv1h8	36	3	,	,	,
cord-293938-40zyv1h8	36	4	CoV	cov	NN
cord-293938-40zyv1h8	36	5	infections	infection	NNS
cord-293938-40zyv1h8	36	6	are	be	VBP
cord-293938-40zyv1h8	36	7	mainly	mainly	RB
cord-293938-40zyv1h8	36	8	associated	associate	VBN
cord-293938-40zyv1h8	36	9	with	with	IN
cord-293938-40zyv1h8	36	10	respiratory	respiratory	JJ
cord-293938-40zyv1h8	36	11	diseases	disease	NNS
cord-293938-40zyv1h8	36	12	that	that	WDT
cord-293938-40zyv1h8	36	13	are	be	VBP
cord-293938-40zyv1h8	36	14	considered	consider	VBN
cord-293938-40zyv1h8	36	15	to	to	TO
cord-293938-40zyv1h8	36	16	have	have	VB
cord-293938-40zyv1h8	36	17	a	a	DT
cord-293938-40zyv1h8	36	18	large	large	JJ
cord-293938-40zyv1h8	36	19	impact	impact	NN
cord-293938-40zyv1h8	36	20	on	on	IN
cord-293938-40zyv1h8	36	21	the	the	DT
cord-293938-40zyv1h8	36	22	economy	economy	NN
cord-293938-40zyv1h8	36	23	due	due	JJ
cord-293938-40zyv1h8	36	24	to	to	IN
cord-293938-40zyv1h8	36	25	reduced	reduce	VBN
cord-293938-40zyv1h8	36	26	productivity	productivity	NN
cord-293938-40zyv1h8	36	27	of	of	IN
cord-293938-40zyv1h8	36	28	the	the	DT
cord-293938-40zyv1h8	36	29	working	work	VBG
cord-293938-40zyv1h8	36	30	population	population	NN
cord-293938-40zyv1h8	36	31	.	.	.
cord-293938-40zyv1h8	37	1	Currently	currently	RB
cord-293938-40zyv1h8	37	2	,	,	,
cord-293938-40zyv1h8	37	3	6	6	CD
cord-293938-40zyv1h8	37	4	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	37	5	that	that	WDT
cord-293938-40zyv1h8	37	6	cause	cause	VBP
cord-293938-40zyv1h8	37	7	disease	disease	NN
cord-293938-40zyv1h8	37	8	in	in	IN
cord-293938-40zyv1h8	37	9	humans	human	NNS
cord-293938-40zyv1h8	37	10	have	have	VBP
cord-293938-40zyv1h8	37	11	been	be	VBN
cord-293938-40zyv1h8	37	12	discovered	discover	VBN
cord-293938-40zyv1h8	37	13	.	.	.
cord-293938-40zyv1h8	38	1	Four	four	CD
cord-293938-40zyv1h8	38	2	of	of	IN
cord-293938-40zyv1h8	38	3	those	those	DT
cord-293938-40zyv1h8	38	4	are	be	VBP
cord-293938-40zyv1h8	38	5	commonly	commonly	RB
cord-293938-40zyv1h8	38	6	circulating	circulate	VBG
cord-293938-40zyv1h8	38	7	and	and	CC
cord-293938-40zyv1h8	38	8	two	two	CD
cord-293938-40zyv1h8	38	9	have	have	VBP
cord-293938-40zyv1h8	38	10	caused	cause	VBN
cord-293938-40zyv1h8	38	11	epidemics	epidemic	NNS
cord-293938-40zyv1h8	38	12	of	of	IN
cord-293938-40zyv1h8	38	13	severe	severe	JJ
cord-293938-40zyv1h8	38	14	acute	acute	JJ
cord-293938-40zyv1h8	38	15	respiratory	respiratory	JJ
cord-293938-40zyv1h8	38	16	disease	disease	NN
cord-293938-40zyv1h8	38	17	.	.	.
cord-293938-40zyv1h8	39	1	The	the	DT
cord-293938-40zyv1h8	39	2	first	first	JJ
cord-293938-40zyv1h8	39	3	human	human	JJ
cord-293938-40zyv1h8	39	4	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	39	5	(	(	-LRB-
cord-293938-40zyv1h8	39	6	HCoV	HCoV	NNP
cord-293938-40zyv1h8	39	7	)	)	-RRB-
cord-293938-40zyv1h8	39	8	,	,	,
cord-293938-40zyv1h8	39	9	B814	B814	NNP
cord-293938-40zyv1h8	39	10	,	,	,
cord-293938-40zyv1h8	39	11	was	be	VBD
cord-293938-40zyv1h8	39	12	described	describe	VBN
cord-293938-40zyv1h8	39	13	in	in	IN
cord-293938-40zyv1h8	39	14	1965	1965	CD
cord-293938-40zyv1h8	39	15	.	.	.
cord-293938-40zyv1h8	40	1	In	in	IN
cord-293938-40zyv1h8	40	2	the	the	DT
cord-293938-40zyv1h8	40	3	following	follow	VBG
cord-293938-40zyv1h8	40	4	years	year	NNS
cord-293938-40zyv1h8	40	5	,	,	,
cord-293938-40zyv1h8	40	6	over	over	IN
cord-293938-40zyv1h8	40	7	30	30	CD
cord-293938-40zyv1h8	40	8	additional	additional	JJ
cord-293938-40zyv1h8	40	9	strains	strain	NNS
cord-293938-40zyv1h8	40	10	were	be	VBD
cord-293938-40zyv1h8	40	11	characterized	characterize	VBN
cord-293938-40zyv1h8	40	12	.	.	.
cord-293938-40zyv1h8	41	1	Ten	ten	CD
cord-293938-40zyv1h8	41	2	of	of	IN
cord-293938-40zyv1h8	41	3	those	those	DT
cord-293938-40zyv1h8	41	4	strains	strain	NNS
cord-293938-40zyv1h8	41	5	could	could	MD
cord-293938-40zyv1h8	41	6	only	only	RB
cord-293938-40zyv1h8	41	7	be	be	VB
cord-293938-40zyv1h8	41	8	isolated	isolate	VBN
cord-293938-40zyv1h8	41	9	from	from	IN
cord-293938-40zyv1h8	41	10	primary	primary	JJ
cord-293938-40zyv1h8	41	11	embryonic	embryonic	JJ
cord-293938-40zyv1h8	41	12	tracheal	tracheal	JJ
cord-293938-40zyv1h8	41	13	organ	organ	NN
cord-293938-40zyv1h8	41	14	culture	culture	NN
cord-293938-40zyv1h8	41	15	.	.	.
cord-293938-40zyv1h8	42	1	Others	other	NNS
cord-293938-40zyv1h8	42	2	were	be	VBD
cord-293938-40zyv1h8	42	3	readily	readily	RB
cord-293938-40zyv1h8	42	4	isolated	isolate	VBN
cord-293938-40zyv1h8	42	5	from	from	IN
cord-293938-40zyv1h8	42	6	monolayer	monolayer	NN
cord-293938-40zyv1h8	42	7	cultures	culture	NNS
cord-293938-40zyv1h8	42	8	and	and	CC
cord-293938-40zyv1h8	42	9	were	be	VBD
cord-293938-40zyv1h8	42	10	antigenically	antigenically	RB
cord-293938-40zyv1h8	42	11	related	relate	VBN
cord-293938-40zyv1h8	42	12	to	to	IN
cord-293938-40zyv1h8	42	13	the	the	DT
cord-293938-40zyv1h8	42	14	prototype	prototype	NN
cord-293938-40zyv1h8	42	15	strain	strain	VB
cord-293938-40zyv1h8	42	16	HCoV-229E.	HCoV-229E.	NNP
cord-293938-40zyv1h8	42	17	HCoV	HCoV	NNP
cord-293938-40zyv1h8	42	18	-	-	HYPH
cord-293938-40zyv1h8	42	19	OC43	OC43	NNP
cord-293938-40zyv1h8	42	20	,	,	,
cord-293938-40zyv1h8	42	21	for	for	IN
cord-293938-40zyv1h8	42	22	organ	organ	NN
cord-293938-40zyv1h8	42	23	culture	culture	NN
cord-293938-40zyv1h8	42	24	43	43	CD
cord-293938-40zyv1h8	42	25	,	,	,
cord-293938-40zyv1h8	42	26	was	be	VBD
cord-293938-40zyv1h8	42	27	isolated	isolate	VBN
cord-293938-40zyv1h8	42	28	and	and	CC
cord-293938-40zyv1h8	42	29	found	find	VBN
cord-293938-40zyv1h8	42	30	to	to	TO
cord-293938-40zyv1h8	42	31	be	be	VB
cord-293938-40zyv1h8	42	32	distinct	distinct	JJ
cord-293938-40zyv1h8	42	33	from	from	IN
cord-293938-40zyv1h8	42	34	the	the	DT
cord-293938-40zyv1h8	42	35	229E	229e	CD
cord-293938-40zyv1h8	42	36	prototype	prototype	NN
cord-293938-40zyv1h8	42	37	strain	strain	NN
cord-293938-40zyv1h8	42	38	[	[	-LRB-
cord-293938-40zyv1h8	42	39	11	11	CD
cord-293938-40zyv1h8	42	40	,	,	,
cord-293938-40zyv1h8	42	41	12	12	CD
cord-293938-40zyv1h8	42	42	]	]	-RRB-
cord-293938-40zyv1h8	42	43	.	.	.
cord-293938-40zyv1h8	43	1	In	in	IN
cord-293938-40zyv1h8	43	2	the	the	DT
cord-293938-40zyv1h8	43	3	subsequent	subsequent	JJ
cord-293938-40zyv1h8	43	4	decades	decade	NNS
cord-293938-40zyv1h8	43	5	,	,	,
cord-293938-40zyv1h8	43	6	research	research	NN
cord-293938-40zyv1h8	43	7	on	on	IN
cord-293938-40zyv1h8	43	8	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	43	9	would	would	MD
cord-293938-40zyv1h8	43	10	center	center	VB
cord-293938-40zyv1h8	43	11	on	on	IN
cord-293938-40zyv1h8	43	12	these	these	DT
cord-293938-40zyv1h8	43	13	two	two	CD
cord-293938-40zyv1h8	43	14	distinct	distinct	JJ
cord-293938-40zyv1h8	43	15	viruses	virus	NNS
cord-293938-40zyv1h8	43	16	.	.	.
cord-293938-40zyv1h8	44	1	However	however	RB
cord-293938-40zyv1h8	44	2	,	,	,
cord-293938-40zyv1h8	44	3	in	in	IN
cord-293938-40zyv1h8	44	4	2002	2002	CD
cord-293938-40zyv1h8	44	5	,	,	,
cord-293938-40zyv1h8	44	6	an	an	DT
cord-293938-40zyv1h8	44	7	unknown	unknown	JJ
cord-293938-40zyv1h8	44	8	respiratory	respiratory	JJ
cord-293938-40zyv1h8	44	9	illness	illness	NN
cord-293938-40zyv1h8	44	10	,	,	,
cord-293938-40zyv1h8	44	11	termed	term	VBN
cord-293938-40zyv1h8	44	12	Severe	severe	JJ
cord-293938-40zyv1h8	44	13	Acute	acute	JJ
cord-293938-40zyv1h8	44	14	Respiratory	Respiratory	NNP
cord-293938-40zyv1h8	44	15	Syndrome	Syndrome	NNP
cord-293938-40zyv1h8	44	16	(	(	-LRB-
cord-293938-40zyv1h8	44	17	SARS	SARS	NNP
cord-293938-40zyv1h8	44	18	)	)	-RRB-
cord-293938-40zyv1h8	44	19	,	,	,
cord-293938-40zyv1h8	44	20	surfaced	surface	VBD
cord-293938-40zyv1h8	44	21	in	in	IN
cord-293938-40zyv1h8	44	22	Asia	Asia	NNP
cord-293938-40zyv1h8	44	23	.	.	.
cord-293938-40zyv1h8	45	1	Research	research	NN
cord-293938-40zyv1h8	45	2	determined	determine	VBD
cord-293938-40zyv1h8	45	3	it	-PRON-	PRP
cord-293938-40zyv1h8	45	4	to	to	TO
cord-293938-40zyv1h8	45	5	be	be	VB
cord-293938-40zyv1h8	45	6	caused	cause	VBN
cord-293938-40zyv1h8	45	7	by	by	IN
cord-293938-40zyv1h8	45	8	a	a	DT
cord-293938-40zyv1h8	45	9	novel	novel	JJ
cord-293938-40zyv1h8	45	10	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	45	11	[	[	-LRB-
cord-293938-40zyv1h8	45	12	13	13	CD
cord-293938-40zyv1h8	45	13	,	,	,
cord-293938-40zyv1h8	45	14	14	14	CD
cord-293938-40zyv1h8	45	15	]	]	-RRB-
cord-293938-40zyv1h8	45	16	.	.	.
cord-293938-40zyv1h8	46	1	At	at	IN
cord-293938-40zyv1h8	46	2	the	the	DT
cord-293938-40zyv1h8	46	3	end	end	NN
cord-293938-40zyv1h8	46	4	of	of	IN
cord-293938-40zyv1h8	46	5	the	the	DT
cord-293938-40zyv1h8	46	6	epidemic	epidemic	NN
cord-293938-40zyv1h8	46	7	,	,	,
cord-293938-40zyv1h8	46	8	this	this	DT
cord-293938-40zyv1h8	46	9	virus	virus	NN
cord-293938-40zyv1h8	46	10	had	have	VBD
cord-293938-40zyv1h8	46	11	infected	infect	VBN
cord-293938-40zyv1h8	46	12	over	over	IN
cord-293938-40zyv1h8	46	13	8000	8000	CD
cord-293938-40zyv1h8	46	14	people	people	NNS
cord-293938-40zyv1h8	46	15	,	,	,
cord-293938-40zyv1h8	46	16	most	most	JJS
cord-293938-40zyv1h8	46	17	in	in	IN
cord-293938-40zyv1h8	46	18	China	China	NNP
cord-293938-40zyv1h8	46	19	,	,	,
cord-293938-40zyv1h8	46	20	and	and	CC
cord-293938-40zyv1h8	46	21	caused	cause	VBD
cord-293938-40zyv1h8	46	22	774	774	CD
cord-293938-40zyv1h8	46	23	deaths	death	NNS
cord-293938-40zyv1h8	46	24	[	[	-LRB-
cord-293938-40zyv1h8	46	25	15	15	CD
cord-293938-40zyv1h8	46	26	]	]	-RRB-
cord-293938-40zyv1h8	46	27	.	.	.
cord-293938-40zyv1h8	47	1	Following	follow	VBG
cord-293938-40zyv1h8	47	2	the	the	DT
cord-293938-40zyv1h8	47	3	discovery	discovery	NN
cord-293938-40zyv1h8	47	4	of	of	IN
cord-293938-40zyv1h8	47	5	this	this	DT
cord-293938-40zyv1h8	47	6	virus	virus	NN
cord-293938-40zyv1h8	47	7	,	,	,
cord-293938-40zyv1h8	47	8	two	two	CD
cord-293938-40zyv1h8	47	9	additional	additional	JJ
cord-293938-40zyv1h8	47	10	CoVs	covs	NN
cord-293938-40zyv1h8	47	11	causing	cause	VBG
cord-293938-40zyv1h8	47	12	human	human	JJ
cord-293938-40zyv1h8	47	13	disease	disease	NN
cord-293938-40zyv1h8	47	14	were	be	VBD
cord-293938-40zyv1h8	47	15	identified	identify	VBN
cord-293938-40zyv1h8	47	16	.	.	.
cord-293938-40zyv1h8	48	1	HCoV	HCoV	NNP
cord-293938-40zyv1h8	49	1	-NL63	-NL63	:
cord-293938-40zyv1h8	49	2	was	be	VBD
cord-293938-40zyv1h8	49	3	isolated	isolate	VBN
cord-293938-40zyv1h8	49	4	in	in	IN
cord-293938-40zyv1h8	49	5	the	the	DT
cord-293938-40zyv1h8	49	6	Netherlands	Netherlands	NNP
cord-293938-40zyv1h8	49	7	in	in	IN
cord-293938-40zyv1h8	49	8	2004	2004	CD
cord-293938-40zyv1h8	49	9	from	from	IN
cord-293938-40zyv1h8	49	10	an	an	DT
cord-293938-40zyv1h8	49	11	infant	infant	NN
cord-293938-40zyv1h8	49	12	with	with	IN
cord-293938-40zyv1h8	49	13	bronchiolitis	bronchiolitis	NN
cord-293938-40zyv1h8	49	14	[	[	-LRB-
cord-293938-40zyv1h8	49	15	16	16	CD
cord-293938-40zyv1h8	49	16	]	]	-RRB-
cord-293938-40zyv1h8	49	17	and	and	CC
cord-293938-40zyv1h8	49	18	HCoV	HCoV	NNP
cord-293938-40zyv1h8	49	19	-	-	HYPH
cord-293938-40zyv1h8	49	20	HKU1	HKU1	NNP
cord-293938-40zyv1h8	49	21	in	in	IN
cord-293938-40zyv1h8	49	22	2005	2005	CD
cord-293938-40zyv1h8	49	23	from	from	IN
cord-293938-40zyv1h8	49	24	a	a	DT
cord-293938-40zyv1h8	49	25	patient	patient	NN
cord-293938-40zyv1h8	49	26	with	with	IN
cord-293938-40zyv1h8	49	27	pneumonia	pneumonia	NN
cord-293938-40zyv1h8	49	28	in	in	IN
cord-293938-40zyv1h8	49	29	Hong	Hong	NNP
cord-293938-40zyv1h8	49	30	Kong	Kong	NNP
cord-293938-40zyv1h8	49	31	[	[	-LRB-
cord-293938-40zyv1h8	49	32	17	17	CD
cord-293938-40zyv1h8	49	33	]	]	-RRB-
cord-293938-40zyv1h8	49	34	.	.	.
cord-293938-40zyv1h8	50	1	In	in	IN
cord-293938-40zyv1h8	50	2	2012	2012	CD
cord-293938-40zyv1h8	50	3	,	,	,
cord-293938-40zyv1h8	50	4	another	another	DT
cord-293938-40zyv1h8	50	5	respiratory	respiratory	JJ
cord-293938-40zyv1h8	50	6	HCoV	hcov	NN
cord-293938-40zyv1h8	50	7	,	,	,
cord-293938-40zyv1h8	50	8	Middle	Middle	NNP
cord-293938-40zyv1h8	50	9	East	East	NNP
cord-293938-40zyv1h8	50	10	Respiratory	Respiratory	NNP
cord-293938-40zyv1h8	50	11	(	(	-LRB-
cord-293938-40zyv1h8	50	12	MERS)-CoV	MERS)-CoV	NNP
cord-293938-40zyv1h8	50	13	,	,	,
cord-293938-40zyv1h8	50	14	was	be	VBD
cord-293938-40zyv1h8	50	15	isolated	isolate	VBN
cord-293938-40zyv1h8	50	16	from	from	IN
cord-293938-40zyv1h8	50	17	a	a	DT
cord-293938-40zyv1h8	50	18	patient	patient	NN
cord-293938-40zyv1h8	50	19	with	with	IN
cord-293938-40zyv1h8	50	20	pneumonia	pneumonia	NN
cord-293938-40zyv1h8	50	21	in	in	IN
cord-293938-40zyv1h8	50	22	Saudi	Saudi	NNP
cord-293938-40zyv1h8	50	23	-	-	HYPH
cord-293938-40zyv1h8	50	24	Arabia	Arabia	NNP
cord-293938-40zyv1h8	50	25	[	[	-LRB-
cord-293938-40zyv1h8	50	26	18	18	CD
cord-293938-40zyv1h8	50	27	]	]	-RRB-
cord-293938-40zyv1h8	50	28	.	.	.
cord-293938-40zyv1h8	51	1	Unlike	unlike	IN
cord-293938-40zyv1h8	51	2	SARS	SARS	NNP
cord-293938-40zyv1h8	51	3	-	-	HYPH
cord-293938-40zyv1h8	51	4	CoV	CoV	NNP
cord-293938-40zyv1h8	51	5	,	,	,
cord-293938-40zyv1h8	51	6	this	this	DT
cord-293938-40zyv1h8	51	7	virus	virus	NN
cord-293938-40zyv1h8	51	8	is	be	VBZ
cord-293938-40zyv1h8	51	9	still	still	RB
cord-293938-40zyv1h8	51	10	intermittently	intermittently	RB
cord-293938-40zyv1h8	51	11	present	present	JJ
cord-293938-40zyv1h8	51	12	in	in	IN
cord-293938-40zyv1h8	51	13	the	the	DT
cord-293938-40zyv1h8	51	14	human	human	JJ
cord-293938-40zyv1h8	51	15	population	population	NN
cord-293938-40zyv1h8	51	16	and	and	CC
cord-293938-40zyv1h8	51	17	most	most	RBS
cord-293938-40zyv1h8	51	18	recently	recently	RB
cord-293938-40zyv1h8	51	19	caused	cause	VBD
cord-293938-40zyv1h8	51	20	a	a	DT
cord-293938-40zyv1h8	51	21	large	large	JJ
cord-293938-40zyv1h8	51	22	outbreak	outbreak	NN
cord-293938-40zyv1h8	51	23	in	in	IN
cord-293938-40zyv1h8	51	24	South	South	NNP
cord-293938-40zyv1h8	51	25	-	-	HYPH
cord-293938-40zyv1h8	51	26	Korea	Korea	NNP
cord-293938-40zyv1h8	51	27	[	[	-LRB-
cord-293938-40zyv1h8	51	28	19	19	CD
cord-293938-40zyv1h8	51	29	]	]	-RRB-
cord-293938-40zyv1h8	51	30	.	.	.
cord-293938-40zyv1h8	52	1	To	to	IN
cord-293938-40zyv1h8	52	2	date	date	NN
cord-293938-40zyv1h8	52	3	,	,	,
cord-293938-40zyv1h8	52	4	there	there	EX
cord-293938-40zyv1h8	52	5	have	have	VBP
cord-293938-40zyv1h8	52	6	been	be	VBN
cord-293938-40zyv1h8	52	7	over	over	IN
cord-293938-40zyv1h8	52	8	1600	1600	CD
cord-293938-40zyv1h8	52	9	cases	case	NNS
cord-293938-40zyv1h8	52	10	and	and	CC
cord-293938-40zyv1h8	52	11	almost	almost	RB
cord-293938-40zyv1h8	52	12	600	600	CD
cord-293938-40zyv1h8	52	13	deaths	death	NNS
cord-293938-40zyv1h8	52	14	related	relate	VBN
cord-293938-40zyv1h8	52	15	to	to	IN
cord-293938-40zyv1h8	52	16	MERS	MERS	NNP
cord-293938-40zyv1h8	52	17	-	-	HYPH
cord-293938-40zyv1h8	52	18	CoV	CoV	NNP
cord-293938-40zyv1h8	52	19	infection	infection	NN
cord-293938-40zyv1h8	52	20	[	[	-LRB-
cord-293938-40zyv1h8	52	21	20	20	CD
cord-293938-40zyv1h8	52	22	]	]	-RRB-
cord-293938-40zyv1h8	52	23	.	.	.
cord-293938-40zyv1h8	53	1	Out	out	IN
cord-293938-40zyv1h8	53	2	of	of	IN
cord-293938-40zyv1h8	53	3	the	the	DT
cord-293938-40zyv1h8	53	4	6	6	CD
cord-293938-40zyv1h8	53	5	known	know	VBN
cord-293938-40zyv1h8	53	6	human	human	JJ
cord-293938-40zyv1h8	53	7	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	53	8	,	,	,
cord-293938-40zyv1h8	53	9	HCoV-229E	HCoV-229E	NNP
cord-293938-40zyv1h8	53	10	,	,	,
cord-293938-40zyv1h8	53	11	HCoV	HCoV	NNP
cord-293938-40zyv1h8	53	12	-	-	HYPH
cord-293938-40zyv1h8	53	13	OC43	OC43	NNP
cord-293938-40zyv1h8	53	14	,	,	,
cord-293938-40zyv1h8	53	15	HCoV	HCoV	NNP
cord-293938-40zyv1h8	53	16	-	-	HYPH
cord-293938-40zyv1h8	53	17	NL63	NL63	NNP
cord-293938-40zyv1h8	53	18	and	and	CC
cord-293938-40zyv1h8	53	19	HCoV	HCoV	NNP
cord-293938-40zyv1h8	53	20	-	-	HYPH
cord-293938-40zyv1h8	53	21	HKU1	HKU1	NNP
cord-293938-40zyv1h8	53	22	are	be	VBP
cord-293938-40zyv1h8	53	23	commonly	commonly	RB
cord-293938-40zyv1h8	53	24	circulating	circulate	VBG
cord-293938-40zyv1h8	53	25	in	in	IN
cord-293938-40zyv1h8	53	26	the	the	DT
cord-293938-40zyv1h8	53	27	human	human	JJ
cord-293938-40zyv1h8	53	28	population	population	NN
cord-293938-40zyv1h8	53	29	and	and	CC
cord-293938-40zyv1h8	53	30	usually	usually	RB
cord-293938-40zyv1h8	53	31	cause	cause	VB
cord-293938-40zyv1h8	53	32	general	general	JJ
cord-293938-40zyv1h8	53	33	respiratory	respiratory	JJ
cord-293938-40zyv1h8	53	34	illness	illness	NN
cord-293938-40zyv1h8	53	35	and	and	CC
cord-293938-40zyv1h8	53	36	cold	cold	JJ
cord-293938-40zyv1h8	53	37	symptoms	symptom	NNS
cord-293938-40zyv1h8	53	38	in	in	IN
cord-293938-40zyv1h8	53	39	healthy	healthy	JJ
cord-293938-40zyv1h8	53	40	individuals	individual	NNS
cord-293938-40zyv1h8	53	41	[	[	-LRB-
cord-293938-40zyv1h8	53	42	21	21	CD
cord-293938-40zyv1h8	53	43	]	]	-RRB-
cord-293938-40zyv1h8	53	44	[	[	-LRB-
cord-293938-40zyv1h8	53	45	22	22	CD
cord-293938-40zyv1h8	53	46	]	]	-RRB-
cord-293938-40zyv1h8	53	47	[	[	-LRB-
cord-293938-40zyv1h8	53	48	23	23	CD
cord-293938-40zyv1h8	53	49	]	]	-RRB-
cord-293938-40zyv1h8	53	50	.	.	.
cord-293938-40zyv1h8	54	1	Like	like	IN
cord-293938-40zyv1h8	54	2	influenza	influenza	NN
cord-293938-40zyv1h8	54	3	,	,	,
cord-293938-40zyv1h8	54	4	these	these	DT
cord-293938-40zyv1h8	54	5	viruses	virus	NNS
cord-293938-40zyv1h8	54	6	are	be	VBP
cord-293938-40zyv1h8	54	7	capable	capable	JJ
cord-293938-40zyv1h8	54	8	of	of	IN
cord-293938-40zyv1h8	54	9	causing	cause	VBG
cord-293938-40zyv1h8	54	10	more	more	RBR
cord-293938-40zyv1h8	54	11	severe	severe	JJ
cord-293938-40zyv1h8	54	12	disease	disease	NN
cord-293938-40zyv1h8	54	13	in	in	IN
cord-293938-40zyv1h8	54	14	the	the	DT
cord-293938-40zyv1h8	54	15	immunocompromised	immunocompromised	JJ
cord-293938-40zyv1h8	54	16	and	and	CC
cord-293938-40zyv1h8	54	17	the	the	DT
cord-293938-40zyv1h8	54	18	elderly	elderly	JJ
cord-293938-40zyv1h8	54	19	[	[	-LRB-
cord-293938-40zyv1h8	54	20	24	24	CD
cord-293938-40zyv1h8	54	21	]	]	-RRB-
cord-293938-40zyv1h8	54	22	.	.	.
cord-293938-40zyv1h8	55	1	They	-PRON-	PRP
cord-293938-40zyv1h8	55	2	infect	infect	VBP
cord-293938-40zyv1h8	55	3	the	the	DT
cord-293938-40zyv1h8	55	4	human	human	JJ
cord-293938-40zyv1h8	55	5	airway	airway	NN
cord-293938-40zyv1h8	55	6	from	from	IN
cord-293938-40zyv1h8	55	7	the	the	DT
cord-293938-40zyv1h8	55	8	luminal	luminal	JJ
cord-293938-40zyv1h8	55	9	side	side	NN
cord-293938-40zyv1h8	55	10	and	and	CC
cord-293938-40zyv1h8	55	11	progeny	progeny	NN
cord-293938-40zyv1h8	55	12	viruses	virus	NNS
cord-293938-40zyv1h8	55	13	are	be	VBP
cord-293938-40zyv1h8	55	14	released	release	VBN
cord-293938-40zyv1h8	55	15	from	from	IN
cord-293938-40zyv1h8	55	16	the	the	DT
cord-293938-40zyv1h8	55	17	same	same	JJ
cord-293938-40zyv1h8	55	18	side	side	NN
cord-293938-40zyv1h8	55	19	facilitating	facilitate	VBG
cord-293938-40zyv1h8	55	20	spread	spread	VBD
cord-293938-40zyv1h8	55	21	through	through	IN
cord-293938-40zyv1h8	55	22	coughing	coughing	NN
cord-293938-40zyv1h8	55	23	and	and	CC
cord-293938-40zyv1h8	55	24	sneezing	sneeze	VBG
cord-293938-40zyv1h8	55	25	[	[	-LRB-
cord-293938-40zyv1h8	55	26	25	25	CD
cord-293938-40zyv1h8	55	27	,	,	,
cord-293938-40zyv1h8	55	28	26	26	CD
cord-293938-40zyv1h8	55	29	]	]	-RRB-
cord-293938-40zyv1h8	55	30	.	.	.
cord-293938-40zyv1h8	56	1	These	these	DT
cord-293938-40zyv1h8	56	2	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	56	3	are	be	VBP
cord-293938-40zyv1h8	56	4	responsible	responsible	JJ
cord-293938-40zyv1h8	56	5	for	for	IN
cord-293938-40zyv1h8	56	6	approximately	approximately	RB
cord-293938-40zyv1h8	56	7	5	5	CD
cord-293938-40zyv1h8	56	8	-	-	SYM
cord-293938-40zyv1h8	56	9	10	10	CD
cord-293938-40zyv1h8	56	10	%	%	NN
cord-293938-40zyv1h8	56	11	of	of	IN
cord-293938-40zyv1h8	56	12	all	all	DT
cord-293938-40zyv1h8	56	13	upper	upper	JJ
cord-293938-40zyv1h8	56	14	and	and	CC
cord-293938-40zyv1h8	56	15	lower	low	JJR
cord-293938-40zyv1h8	56	16	respiratory	respiratory	JJ
cord-293938-40zyv1h8	56	17	tract	tract	NN
cord-293938-40zyv1h8	56	18	infections	infection	NNS
cord-293938-40zyv1h8	56	19	[	[	-LRB-
cord-293938-40zyv1h8	56	20	27	27	CD
cord-293938-40zyv1h8	56	21	]	]	-RRB-
cord-293938-40zyv1h8	57	1	[	[	-LRB-
cord-293938-40zyv1h8	57	2	28	28	CD
cord-293938-40zyv1h8	57	3	]	]	-RRB-
cord-293938-40zyv1h8	58	1	[	[	-LRB-
cord-293938-40zyv1h8	58	2	29	29	CD
cord-293938-40zyv1h8	58	3	]	]	-RRB-
cord-293938-40zyv1h8	59	1	but	but	CC
cord-293938-40zyv1h8	59	2	the	the	DT
cord-293938-40zyv1h8	59	3	interactions	interaction	NNS
cord-293938-40zyv1h8	59	4	between	between	IN
cord-293938-40zyv1h8	59	5	them	-PRON-	PRP
cord-293938-40zyv1h8	59	6	and	and	CC
cord-293938-40zyv1h8	59	7	their	-PRON-	PRP$
cord-293938-40zyv1h8	59	8	natural	natural	JJ
cord-293938-40zyv1h8	59	9	host	host	NN
cord-293938-40zyv1h8	59	10	cells	cell	NNS
cord-293938-40zyv1h8	59	11	are	be	VBP
cord-293938-40zyv1h8	59	12	poorly	poorly	RB
cord-293938-40zyv1h8	59	13	understood	understand	VBN
cord-293938-40zyv1h8	59	14	.	.	.
cord-293938-40zyv1h8	60	1	Currently	currently	RB
cord-293938-40zyv1h8	60	2	,	,	,
cord-293938-40zyv1h8	60	3	it	-PRON-	PRP
cord-293938-40zyv1h8	60	4	is	be	VBZ
cord-293938-40zyv1h8	60	5	hypothesized	hypothesize	VBN
cord-293938-40zyv1h8	60	6	that	that	IN
cord-293938-40zyv1h8	60	7	most	most	JJS
cord-293938-40zyv1h8	60	8	of	of	IN
cord-293938-40zyv1h8	60	9	the	the	DT
cord-293938-40zyv1h8	60	10	human	human	JJ
cord-293938-40zyv1h8	60	11	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	60	12	may	may	MD
cord-293938-40zyv1h8	60	13	have	have	VB
cord-293938-40zyv1h8	60	14	originated	originate	VBN
cord-293938-40zyv1h8	60	15	from	from	IN
cord-293938-40zyv1h8	60	16	bats	bat	NNS
cord-293938-40zyv1h8	60	17	[	[	-LRB-
cord-293938-40zyv1h8	60	18	30	30	CD
cord-293938-40zyv1h8	60	19	,	,	,
cord-293938-40zyv1h8	60	20	31	31	CD
cord-293938-40zyv1h8	60	21	]	]	-RRB-
cord-293938-40zyv1h8	60	22	.	.	.
cord-293938-40zyv1h8	61	1	For	for	IN
cord-293938-40zyv1h8	61	2	example	example	NN
cord-293938-40zyv1h8	61	3	,	,	,
cord-293938-40zyv1h8	61	4	HCoV-229E	HCoV-229E	NNP
cord-293938-40zyv1h8	61	5	is	be	VBZ
cord-293938-40zyv1h8	61	6	believed	believe	VBN
cord-293938-40zyv1h8	61	7	to	to	TO
cord-293938-40zyv1h8	61	8	originate	originate	VB
cord-293938-40zyv1h8	61	9	from	from	IN
cord-293938-40zyv1h8	61	10	African	african	JJ
cord-293938-40zyv1h8	61	11	hipposiderid	hipposiderid	NN
cord-293938-40zyv1h8	61	12	bats	bat	NNS
cord-293938-40zyv1h8	61	13	possibly	possibly	RB
cord-293938-40zyv1h8	61	14	using	use	VBG
cord-293938-40zyv1h8	61	15	camelids	camelid	NNS
cord-293938-40zyv1h8	61	16	as	as	IN
cord-293938-40zyv1h8	61	17	intermediate	intermediate	JJ
cord-293938-40zyv1h8	61	18	hosts	host	NNS
cord-293938-40zyv1h8	61	19	[	[	-LRB-
cord-293938-40zyv1h8	61	20	32	32	CD
cord-293938-40zyv1h8	61	21	]	]	-RRB-
cord-293938-40zyv1h8	61	22	.	.	.
cord-293938-40zyv1h8	62	1	In	in	IN
cord-293938-40zyv1h8	62	2	the	the	DT
cord-293938-40zyv1h8	62	3	last	last	JJ
cord-293938-40zyv1h8	62	4	15	15	CD
cord-293938-40zyv1h8	62	5	years	year	NNS
cord-293938-40zyv1h8	62	6	,	,	,
cord-293938-40zyv1h8	62	7	two	two	CD
cord-293938-40zyv1h8	62	8	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	62	9	have	have	VBP
cord-293938-40zyv1h8	62	10	crossed	cross	VBN
cord-293938-40zyv1h8	62	11	the	the	DT
cord-293938-40zyv1h8	62	12	species	specie	NNS
cord-293938-40zyv1h8	62	13	barrier	barrier	NN
cord-293938-40zyv1h8	62	14	and	and	CC
cord-293938-40zyv1h8	62	15	caused	cause	VBD
cord-293938-40zyv1h8	62	16	severe	severe	JJ
cord-293938-40zyv1h8	62	17	and	and	CC
cord-293938-40zyv1h8	62	18	fatal	fatal	JJ
cord-293938-40zyv1h8	62	19	disease	disease	NN
cord-293938-40zyv1h8	62	20	in	in	IN
cord-293938-40zyv1h8	62	21	humans	human	NNS
cord-293938-40zyv1h8	62	22	.	.	.
cord-293938-40zyv1h8	63	1	SARS	SARS	NNP
cord-293938-40zyv1h8	63	2	-	-	HYPH
cord-293938-40zyv1h8	63	3	CoV	CoV	NNP
cord-293938-40zyv1h8	63	4	surfaced	surface	VBD
cord-293938-40zyv1h8	63	5	in	in	IN
cord-293938-40zyv1h8	63	6	2002	2002	CD
cord-293938-40zyv1h8	63	7	and	and	CC
cord-293938-40zyv1h8	63	8	MERS	MERS	NNP
cord-293938-40zyv1h8	63	9	-	-	HYPH
cord-293938-40zyv1h8	63	10	CoV	CoV	NNP
cord-293938-40zyv1h8	63	11	in	in	IN
cord-293938-40zyv1h8	63	12	2012	2012	CD
cord-293938-40zyv1h8	63	13	[	[	-LRB-
cord-293938-40zyv1h8	63	14	13	13	CD
cord-293938-40zyv1h8	63	15	,	,	,
cord-293938-40zyv1h8	63	16	14	14	CD
cord-293938-40zyv1h8	63	17	,	,	,
cord-293938-40zyv1h8	63	18	18	18	CD
cord-293938-40zyv1h8	63	19	]	]	-RRB-
cord-293938-40zyv1h8	63	20	.	.	.
cord-293938-40zyv1h8	64	1	As	as	IN
cord-293938-40zyv1h8	64	2	opposed	oppose	VBN
cord-293938-40zyv1h8	64	3	to	to	IN
cord-293938-40zyv1h8	64	4	the	the	DT
cord-293938-40zyv1h8	64	5	commonly	commonly	RB
cord-293938-40zyv1h8	64	6	circulating	circulate	VBG
cord-293938-40zyv1h8	64	7	viruses	virus	NNS
cord-293938-40zyv1h8	64	8	,	,	,
cord-293938-40zyv1h8	64	9	which	which	WDT
cord-293938-40zyv1h8	64	10	generally	generally	RB
cord-293938-40zyv1h8	64	11	only	only	RB
cord-293938-40zyv1h8	64	12	cause	cause	VBP
cord-293938-40zyv1h8	64	13	mild	mild	JJ
cord-293938-40zyv1h8	64	14	respiratory	respiratory	JJ
cord-293938-40zyv1h8	64	15	symptoms	symptom	NNS
cord-293938-40zyv1h8	64	16	,	,	,
cord-293938-40zyv1h8	64	17	these	these	DT
cord-293938-40zyv1h8	64	18	viruses	virus	NNS
cord-293938-40zyv1h8	64	19	presented	present	VBN
cord-293938-40zyv1h8	64	20	with	with	IN
cord-293938-40zyv1h8	64	21	higher	high	JJR
cord-293938-40zyv1h8	64	22	case	case	NN
cord-293938-40zyv1h8	64	23	fatality	fatality	NN
cord-293938-40zyv1h8	64	24	ratios	ratio	NNS
cord-293938-40zyv1h8	64	25	,	,	,
cord-293938-40zyv1h8	64	26	around	around	IN
cord-293938-40zyv1h8	64	27	10	10	CD
cord-293938-40zyv1h8	64	28	and	and	CC
cord-293938-40zyv1h8	64	29	20	20	CD
cord-293938-40zyv1h8	64	30	-	-	SYM
cord-293938-40zyv1h8	64	31	50	50	CD
cord-293938-40zyv1h8	64	32	%	%	NN
cord-293938-40zyv1h8	64	33	respectively	respectively	RB
cord-293938-40zyv1h8	64	34	[	[	-LRB-
cord-293938-40zyv1h8	64	35	33	33	CD
cord-293938-40zyv1h8	64	36	,	,	,
cord-293938-40zyv1h8	64	37	34	34	CD
cord-293938-40zyv1h8	64	38	]	]	-RRB-
cord-293938-40zyv1h8	64	39	.	.	.
cord-293938-40zyv1h8	65	1	Currently	currently	RB
cord-293938-40zyv1h8	65	2	,	,	,
cord-293938-40zyv1h8	65	3	there	there	EX
cord-293938-40zyv1h8	65	4	is	be	VBZ
cord-293938-40zyv1h8	65	5	abundant	abundant	JJ
cord-293938-40zyv1h8	65	6	phylogenetic	phylogenetic	JJ
cord-293938-40zyv1h8	65	7	evidence	evidence	NN
cord-293938-40zyv1h8	65	8	for	for	IN
cord-293938-40zyv1h8	65	9	the	the	DT
cord-293938-40zyv1h8	65	10	bat	bat	NN
cord-293938-40zyv1h8	65	11	origin	origin	NN
cord-293938-40zyv1h8	65	12	of	of	IN
cord-293938-40zyv1h8	65	13	SARS	SARS	NNP
cord-293938-40zyv1h8	65	14	-	-	HYPH
cord-293938-40zyv1h8	65	15	CoV	CoV	NNP
cord-293938-40zyv1h8	65	16	,	,	,
cord-293938-40zyv1h8	65	17	based	base	VBN
cord-293938-40zyv1h8	65	18	on	on	IN
cord-293938-40zyv1h8	65	19	sequences	sequence	NNS
cord-293938-40zyv1h8	65	20	of	of	IN
cord-293938-40zyv1h8	65	21	SARS	SARS	NNP
cord-293938-40zyv1h8	65	22	-	-	HYPH
cord-293938-40zyv1h8	65	23	like	like	JJ
cord-293938-40zyv1h8	65	24	viruses	virus	NNS
cord-293938-40zyv1h8	65	25	found	find	VBN
cord-293938-40zyv1h8	65	26	among	among	IN
cord-293938-40zyv1h8	65	27	bats	bat	NNS
cord-293938-40zyv1h8	65	28	in	in	IN
cord-293938-40zyv1h8	65	29	the	the	DT
cord-293938-40zyv1h8	65	30	recent	recent	JJ
cord-293938-40zyv1h8	65	31	years	year	NNS
cord-293938-40zyv1h8	65	32	[	[	-LRB-
cord-293938-40zyv1h8	65	33	35	35	CD
cord-293938-40zyv1h8	65	34	]	]	-RRB-
cord-293938-40zyv1h8	66	1	[	[	-LRB-
cord-293938-40zyv1h8	66	2	36	36	CD
cord-293938-40zyv1h8	66	3	]	]	-RRB-
cord-293938-40zyv1h8	66	4	[	[	-LRB-
cord-293938-40zyv1h8	66	5	37	37	CD
cord-293938-40zyv1h8	66	6	]	]	-RRB-
cord-293938-40zyv1h8	66	7	.	.	.
cord-293938-40zyv1h8	67	1	The	the	DT
cord-293938-40zyv1h8	67	2	initial	initial	JJ
cord-293938-40zyv1h8	67	3	transmissions	transmission	NNS
cord-293938-40zyv1h8	67	4	of	of	IN
cord-293938-40zyv1h8	67	5	SARS	SARS	NNP
cord-293938-40zyv1h8	67	6	-	-	HYPH
cord-293938-40zyv1h8	67	7	CoV	CoV	NNP
cord-293938-40zyv1h8	67	8	from	from	IN
cord-293938-40zyv1h8	67	9	animals	animal	NNS
cord-293938-40zyv1h8	67	10	to	to	IN
cord-293938-40zyv1h8	67	11	humans	human	NNS
cord-293938-40zyv1h8	67	12	were	be	VBD
cord-293938-40zyv1h8	67	13	traced	trace	VBN
cord-293938-40zyv1h8	67	14	back	back	RB
cord-293938-40zyv1h8	67	15	to	to	IN
cord-293938-40zyv1h8	67	16	the	the	DT
cord-293938-40zyv1h8	67	17	live	live	JJ
cord-293938-40zyv1h8	67	18	animal	animal	NN
cord-293938-40zyv1h8	67	19	wet	wet	JJ
cord-293938-40zyv1h8	67	20	markets	market	NNS
cord-293938-40zyv1h8	67	21	and	and	CC
cord-293938-40zyv1h8	67	22	it	-PRON-	PRP
cord-293938-40zyv1h8	67	23	was	be	VBD
cord-293938-40zyv1h8	67	24	hypothesized	hypothesize	VBN
cord-293938-40zyv1h8	67	25	that	that	IN
cord-293938-40zyv1h8	67	26	the	the	DT
cord-293938-40zyv1h8	67	27	virus	virus	NN
cord-293938-40zyv1h8	67	28	made	make	VBD
cord-293938-40zyv1h8	67	29	its	-PRON-	PRP$
cord-293938-40zyv1h8	67	30	way	way	NN
cord-293938-40zyv1h8	67	31	into	into	IN
cord-293938-40zyv1h8	67	32	the	the	DT
cord-293938-40zyv1h8	67	33	human	human	JJ
cord-293938-40zyv1h8	67	34	population	population	NN
cord-293938-40zyv1h8	67	35	using	use	VBG
cord-293938-40zyv1h8	67	36	the	the	DT
cord-293938-40zyv1h8	67	37	civet	civet	NN
cord-293938-40zyv1h8	67	38	cat	cat	NN
cord-293938-40zyv1h8	67	39	as	as	IN
cord-293938-40zyv1h8	67	40	an	an	DT
cord-293938-40zyv1h8	67	41	intermediate	intermediate	JJ
cord-293938-40zyv1h8	67	42	host	host	NN
cord-293938-40zyv1h8	67	43	.	.	.
cord-293938-40zyv1h8	68	1	However	however	RB
cord-293938-40zyv1h8	68	2	,	,	,
cord-293938-40zyv1h8	68	3	successful	successful	JJ
cord-293938-40zyv1h8	68	4	isolation	isolation	NN
cord-293938-40zyv1h8	68	5	of	of	IN
cord-293938-40zyv1h8	68	6	SARS	SARS	NNP
cord-293938-40zyv1h8	68	7	-	-	HYPH
cord-293938-40zyv1h8	68	8	like	like	JJ
cord-293938-40zyv1h8	68	9	viruses	virus	NNS
cord-293938-40zyv1h8	68	10	from	from	IN
cord-293938-40zyv1h8	68	11	bats	bat	NNS
cord-293938-40zyv1h8	68	12	[	[	-LRB-
cord-293938-40zyv1h8	68	13	38	38	CD
cord-293938-40zyv1h8	68	14	]	]	-RRB-
cord-293938-40zyv1h8	68	15	and	and	CC
cord-293938-40zyv1h8	68	16	the	the	DT
cord-293938-40zyv1h8	68	17	fact	fact	NN
cord-293938-40zyv1h8	68	18	that	that	IN
cord-293938-40zyv1h8	68	19	a	a	DT
cord-293938-40zyv1h8	68	20	contemporary	contemporary	JJ
cord-293938-40zyv1h8	68	21	bat	bat	NN
cord-293938-40zyv1h8	68	22	SARS	SARS	NNP
cord-293938-40zyv1h8	68	23	-	-	HYPH
cord-293938-40zyv1h8	68	24	like	like	JJ
cord-293938-40zyv1h8	68	25	virus	virus	NN
cord-293938-40zyv1h8	68	26	can	can	MD
cord-293938-40zyv1h8	68	27	infect	infect	VB
cord-293938-40zyv1h8	68	28	human	human	JJ
cord-293938-40zyv1h8	68	29	airway	airway	NN
cord-293938-40zyv1h8	68	30	cultures	culture	NNS
cord-293938-40zyv1h8	68	31	[	[	-LRB-
cord-293938-40zyv1h8	68	32	39	39	CD
cord-293938-40zyv1h8	68	33	]	]	-RRB-
cord-293938-40zyv1h8	68	34	suggest	suggest	VBP
cord-293938-40zyv1h8	68	35	that	that	IN
cord-293938-40zyv1h8	68	36	an	an	DT
cord-293938-40zyv1h8	68	37	intermediate	intermediate	JJ
cord-293938-40zyv1h8	68	38	host	host	NN
cord-293938-40zyv1h8	68	39	between	between	IN
cord-293938-40zyv1h8	68	40	humans	human	NNS
cord-293938-40zyv1h8	68	41	and	and	CC
cord-293938-40zyv1h8	68	42	bat	bat	NN
cord-293938-40zyv1h8	68	43	might	may	MD
cord-293938-40zyv1h8	68	44	not	not	RB
cord-293938-40zyv1h8	68	45	have	have	VB
cord-293938-40zyv1h8	68	46	been	be	VBN
cord-293938-40zyv1h8	68	47	needed	need	VBN
cord-293938-40zyv1h8	68	48	for	for	IN
cord-293938-40zyv1h8	68	49	the	the	DT
cord-293938-40zyv1h8	68	50	transmission	transmission	NN
cord-293938-40zyv1h8	68	51	of	of	IN
cord-293938-40zyv1h8	68	52	SARS	SARS	NNP
cord-293938-40zyv1h8	69	1	-CoV.	-cov.	ADD
cord-293938-40zyv1h8	70	1	The	the	DT
cord-293938-40zyv1h8	70	2	evolutionary	evolutionary	JJ
cord-293938-40zyv1h8	70	3	origin	origin	NN
cord-293938-40zyv1h8	70	4	of	of	IN
cord-293938-40zyv1h8	70	5	MERS	MERS	NNP
cord-293938-40zyv1h8	70	6	-	-	HYPH
cord-293938-40zyv1h8	70	7	CoV	CoV	NNP
cord-293938-40zyv1h8	70	8	is	be	VBZ
cord-293938-40zyv1h8	70	9	less	less	RBR
cord-293938-40zyv1h8	70	10	clear	clear	JJ
cord-293938-40zyv1h8	70	11	but	but	CC
cord-293938-40zyv1h8	70	12	it	-PRON-	PRP
cord-293938-40zyv1h8	70	13	has	have	VBZ
cord-293938-40zyv1h8	70	14	been	be	VBN
cord-293938-40zyv1h8	70	15	speculated	speculate	VBN
cord-293938-40zyv1h8	70	16	to	to	TO
cord-293938-40zyv1h8	70	17	be	be	VB
cord-293938-40zyv1h8	70	18	bats	bat	NNS
cord-293938-40zyv1h8	70	19	as	as	RB
cord-293938-40zyv1h8	70	20	well	well	RB
cord-293938-40zyv1h8	70	21	.	.	.
cord-293938-40zyv1h8	71	1	Characterization	characterization	NN
cord-293938-40zyv1h8	71	2	of	of	IN
cord-293938-40zyv1h8	71	3	an	an	DT
cord-293938-40zyv1h8	71	4	African	african	JJ
cord-293938-40zyv1h8	71	5	bat	bat	NN
cord-293938-40zyv1h8	71	6	virus	virus	NN
cord-293938-40zyv1h8	71	7	closely	closely	RB
cord-293938-40zyv1h8	71	8	related	relate	VBN
cord-293938-40zyv1h8	71	9	to	to	IN
cord-293938-40zyv1h8	71	10	MERS	MERS	NNP
cord-293938-40zyv1h8	71	11	-	-	HYPH
cord-293938-40zyv1h8	71	12	CoV	CoV	NNP
cord-293938-40zyv1h8	71	13	shows	show	VBZ
cord-293938-40zyv1h8	71	14	that	that	IN
cord-293938-40zyv1h8	71	15	both	both	CC
cord-293938-40zyv1h8	71	16	the	the	DT
cord-293938-40zyv1h8	71	17	human	human	JJ
cord-293938-40zyv1h8	71	18	and	and	CC
cord-293938-40zyv1h8	71	19	camel	camel	NN
cord-293938-40zyv1h8	71	20	strains	strain	NNS
cord-293938-40zyv1h8	71	21	belong	belong	VBP
cord-293938-40zyv1h8	71	22	to	to	IN
cord-293938-40zyv1h8	71	23	the	the	DT
cord-293938-40zyv1h8	71	24	same	same	JJ
cord-293938-40zyv1h8	71	25	viral	viral	JJ
cord-293938-40zyv1h8	71	26	species	specie	NNS
cord-293938-40zyv1h8	71	27	and	and	CC
cord-293938-40zyv1h8	72	1	phylogenetic	phylogenetic	NNP
cord-293938-40zyv1h8	72	2	analysis	analysis	NN
cord-293938-40zyv1h8	72	3	suggests	suggest	VBZ
cord-293938-40zyv1h8	72	4	that	that	IN
cord-293938-40zyv1h8	72	5	MERS	MERS	NNP
cord-293938-40zyv1h8	72	6	-	-	HYPH
cord-293938-40zyv1h8	72	7	CoV	cov	NN
cord-293938-40zyv1h8	72	8	infection	infection	NN
cord-293938-40zyv1h8	72	9	in	in	IN
cord-293938-40zyv1h8	72	10	camels	camel	NNS
cord-293938-40zyv1h8	72	11	predates	predate	VBZ
cord-293938-40zyv1h8	72	12	that	that	IN
cord-293938-40zyv1h8	72	13	in	in	IN
cord-293938-40zyv1h8	72	14	humans	human	NNS
cord-293938-40zyv1h8	72	15	,	,	,
cord-293938-40zyv1h8	72	16	suggesting	suggest	VBG
cord-293938-40zyv1h8	72	17	that	that	IN
cord-293938-40zyv1h8	72	18	camels	camel	NNS
cord-293938-40zyv1h8	72	19	infect	infect	VBP
cord-293938-40zyv1h8	72	20	humans	human	NNS
cord-293938-40zyv1h8	72	21	and	and	CC
cord-293938-40zyv1h8	72	22	not	not	RB
cord-293938-40zyv1h8	72	23	the	the	DT
cord-293938-40zyv1h8	72	24	other	other	JJ
cord-293938-40zyv1h8	72	25	way	way	NN
cord-293938-40zyv1h8	72	26	around	around	RB
cord-293938-40zyv1h8	72	27	.	.	.
cord-293938-40zyv1h8	73	1	Furthermore	furthermore	RB
cord-293938-40zyv1h8	73	2	,	,	,
cord-293938-40zyv1h8	73	3	the	the	DT
cord-293938-40zyv1h8	73	4	bat	bat	NN
cord-293938-40zyv1h8	73	5	virus	virus	NN
cord-293938-40zyv1h8	73	6	roots	root	VBZ
cord-293938-40zyv1h8	73	7	the	the	DT
cord-293938-40zyv1h8	73	8	phylogenetic	phylogenetic	JJ
cord-293938-40zyv1h8	73	9	tree	tree	NN
cord-293938-40zyv1h8	73	10	providing	provide	VBG
cord-293938-40zyv1h8	73	11	further	further	JJ
cord-293938-40zyv1h8	73	12	evidence	evidence	NN
cord-293938-40zyv1h8	73	13	for	for	IN
cord-293938-40zyv1h8	73	14	the	the	DT
cord-293938-40zyv1h8	73	15	bat	bat	NN
cord-293938-40zyv1h8	73	16	origin	origin	NN
cord-293938-40zyv1h8	73	17	of	of	IN
cord-293938-40zyv1h8	73	18	MERS	MERS	NNP
cord-293938-40zyv1h8	73	19	-	-	HYPH
cord-293938-40zyv1h8	73	20	CoV	CoV	NNP
cord-293938-40zyv1h8	73	21	[	[	-LRB-
cord-293938-40zyv1h8	73	22	40	40	CD
cord-293938-40zyv1h8	73	23	]	]	-RRB-
cord-293938-40zyv1h8	73	24	.	.	.
cord-293938-40zyv1h8	74	1	Additionally	additionally	RB
cord-293938-40zyv1h8	74	2	,	,	,
cord-293938-40zyv1h8	74	3	human	human	JJ
cord-293938-40zyv1h8	74	4	-	-	HYPH
cord-293938-40zyv1h8	74	5	tohuman	tohuman	NN
cord-293938-40zyv1h8	74	6	transmission	transmission	NN
cord-293938-40zyv1h8	74	7	,	,	,
cord-293938-40zyv1h8	74	8	although	although	IN
cord-293938-40zyv1h8	74	9	not	not	RB
cord-293938-40zyv1h8	74	10	robust	robust	JJ
cord-293938-40zyv1h8	74	11	,	,	,
cord-293938-40zyv1h8	74	12	seems	seem	VBZ
cord-293938-40zyv1h8	74	13	to	to	TO
cord-293938-40zyv1h8	74	14	happen	happen	VB
cord-293938-40zyv1h8	74	15	simultaneously	simultaneously	RB
cord-293938-40zyv1h8	74	16	as	as	IN
cord-293938-40zyv1h8	74	17	camel	camel	NN
cord-293938-40zyv1h8	74	18	-	-	HYPH
cord-293938-40zyv1h8	74	19	to	to	IN
cord-293938-40zyv1h8	74	20	-	-	HYPH
cord-293938-40zyv1h8	74	21	human	human	JJ
cord-293938-40zyv1h8	74	22	transmission	transmission	NN
cord-293938-40zyv1h8	74	23	.	.	.
cord-293938-40zyv1h8	75	1	Therefore	therefore	RB
cord-293938-40zyv1h8	75	2	,	,	,
cord-293938-40zyv1h8	75	3	any	any	DT
cord-293938-40zyv1h8	75	4	further	further	JJ
cord-293938-40zyv1h8	75	5	adaptation	adaptation	NN
cord-293938-40zyv1h8	75	6	of	of	IN
cord-293938-40zyv1h8	75	7	MERS	MERS	NNP
cord-293938-40zyv1h8	75	8	-	-	HYPH
cord-293938-40zyv1h8	75	9	CoV	CoV	NNP
cord-293938-40zyv1h8	75	10	to	to	IN
cord-293938-40zyv1h8	75	11	the	the	DT
cord-293938-40zyv1h8	75	12	human	human	JJ
cord-293938-40zyv1h8	75	13	host	host	NN
cord-293938-40zyv1h8	75	14	must	must	MD
cord-293938-40zyv1h8	75	15	be	be	VB
cord-293938-40zyv1h8	75	16	monitored	monitor	VBN
cord-293938-40zyv1h8	75	17	carefully	carefully	RB
cord-293938-40zyv1h8	75	18	and	and	CC
cord-293938-40zyv1h8	75	19	intermediate	intermediate	JJ
cord-293938-40zyv1h8	75	20	hosts	host	NNS
cord-293938-40zyv1h8	75	21	identified	identify	VBD
cord-293938-40zyv1h8	75	22	[	[	-LRB-
cord-293938-40zyv1h8	75	23	41	41	CD
cord-293938-40zyv1h8	75	24	]	]	-RRB-
cord-293938-40zyv1h8	75	25	.	.	.
cord-293938-40zyv1h8	76	1	Many	many	JJ
cord-293938-40zyv1h8	76	2	bat	bat	NN
cord-293938-40zyv1h8	76	3	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	76	4	have	have	VBP
cord-293938-40zyv1h8	76	5	been	be	VBN
cord-293938-40zyv1h8	76	6	identified	identify	VBN
cord-293938-40zyv1h8	76	7	in	in	IN
cord-293938-40zyv1h8	76	8	the	the	DT
cord-293938-40zyv1h8	76	9	recent	recent	JJ
cord-293938-40zyv1h8	76	10	years	year	NNS
cord-293938-40zyv1h8	76	11	further	further	RB
cord-293938-40zyv1h8	76	12	highlighting	highlight	VBG
cord-293938-40zyv1h8	76	13	the	the	DT
cord-293938-40zyv1h8	76	14	zoonotic	zoonotic	JJ
cord-293938-40zyv1h8	76	15	potential	potential	NN
cord-293938-40zyv1h8	76	16	of	of	IN
cord-293938-40zyv1h8	76	17	this	this	DT
cord-293938-40zyv1h8	76	18	family	family	NN
cord-293938-40zyv1h8	76	19	of	of	IN
cord-293938-40zyv1h8	76	20	viruses	virus	NNS
cord-293938-40zyv1h8	76	21	[	[	-LRB-
cord-293938-40zyv1h8	76	22	30	30	CD
cord-293938-40zyv1h8	76	23	]	]	-RRB-
cord-293938-40zyv1h8	76	24	.	.	.
cord-293938-40zyv1h8	77	1	Given	give	VBN
cord-293938-40zyv1h8	77	2	the	the	DT
cord-293938-40zyv1h8	77	3	documented	document	VBN
cord-293938-40zyv1h8	77	4	history	history	NN
cord-293938-40zyv1h8	77	5	of	of	IN
cord-293938-40zyv1h8	77	6	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	77	7	overcoming	overcome	VBG
cord-293938-40zyv1h8	77	8	the	the	DT
cord-293938-40zyv1h8	77	9	species	specie	NNS
cord-293938-40zyv1h8	77	10	barrier	barrier	NN
cord-293938-40zyv1h8	77	11	and	and	CC
cord-293938-40zyv1h8	77	12	causing	cause	VBG
cord-293938-40zyv1h8	77	13	severe	severe	JJ
cord-293938-40zyv1h8	77	14	disease	disease	NN
cord-293938-40zyv1h8	77	15	in	in	IN
cord-293938-40zyv1h8	77	16	humans	human	NNS
cord-293938-40zyv1h8	77	17	,	,	,
cord-293938-40zyv1h8	77	18	it	-PRON-	PRP
cord-293938-40zyv1h8	77	19	is	be	VBZ
cord-293938-40zyv1h8	77	20	important	important	JJ
cord-293938-40zyv1h8	77	21	to	to	TO
cord-293938-40zyv1h8	77	22	investigate	investigate	VB
cord-293938-40zyv1h8	77	23	the	the	DT
cord-293938-40zyv1h8	77	24	zoonotic	zoonotic	JJ
cord-293938-40zyv1h8	77	25	potential	potential	NN
cord-293938-40zyv1h8	77	26	of	of	IN
cord-293938-40zyv1h8	77	27	close	close	JJ
cord-293938-40zyv1h8	77	28	evolutionary	evolutionary	JJ
cord-293938-40zyv1h8	77	29	relatives	relative	NNS
cord-293938-40zyv1h8	77	30	of	of	IN
cord-293938-40zyv1h8	77	31	common	common	JJ
cord-293938-40zyv1h8	77	32	HCoVs	hcovs	NN
cord-293938-40zyv1h8	77	33	in	in	IN
cord-293938-40zyv1h8	77	34	a	a	DT
cord-293938-40zyv1h8	77	35	culture	culture	NN
cord-293938-40zyv1h8	77	36	model	model	NN
cord-293938-40zyv1h8	77	37	that	that	WDT
cord-293938-40zyv1h8	77	38	recapitulates	recapitulate	VBZ
cord-293938-40zyv1h8	77	39	the	the	DT
cord-293938-40zyv1h8	77	40	aspects	aspect	NNS
cord-293938-40zyv1h8	77	41	of	of	IN
cord-293938-40zyv1h8	77	42	the	the	DT
cord-293938-40zyv1h8	77	43	human	human	JJ
cord-293938-40zyv1h8	77	44	airway	airway	NN
cord-293938-40zyv1h8	77	45	,	,	,
cord-293938-40zyv1h8	77	46	e.g.	e.g.	RB
cord-293938-40zyv1h8	77	47	morphology	morphology	NN
cord-293938-40zyv1h8	77	48	and	and	CC
cord-293938-40zyv1h8	77	49	receptor	receptor	NN
cord-293938-40zyv1h8	77	50	distribution	distribution	NN
cord-293938-40zyv1h8	77	51	.	.	.
cord-293938-40zyv1h8	78	1	It	-PRON-	PRP
cord-293938-40zyv1h8	78	2	's	be	VBZ
cord-293938-40zyv1h8	78	3	important	important	JJ
cord-293938-40zyv1h8	78	4	to	to	TO
cord-293938-40zyv1h8	78	5	study	study	VB
cord-293938-40zyv1h8	78	6	the	the	DT
cord-293938-40zyv1h8	78	7	mechanisms	mechanism	NNS
cord-293938-40zyv1h8	78	8	of	of	IN
cord-293938-40zyv1h8	78	9	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	78	10	and	and	CC
cord-293938-40zyv1h8	78	11	the	the	DT
cord-293938-40zyv1h8	78	12	evolution	evolution	NN
cord-293938-40zyv1h8	78	13	of	of	IN
cord-293938-40zyv1h8	78	14	zoonotic	zoonotic	JJ
cord-293938-40zyv1h8	78	15	viruses	virus	NNS
cord-293938-40zyv1h8	78	16	in	in	IN
cord-293938-40zyv1h8	78	17	detail	detail	NN
cord-293938-40zyv1h8	78	18	in	in	IN
cord-293938-40zyv1h8	78	19	order	order	NN
cord-293938-40zyv1h8	78	20	to	to	TO
cord-293938-40zyv1h8	78	21	identify	identify	VB
cord-293938-40zyv1h8	78	22	molecular	molecular	JJ
cord-293938-40zyv1h8	78	23	determinants	determinant	NNS
cord-293938-40zyv1h8	78	24	that	that	WDT
cord-293938-40zyv1h8	78	25	affect	affect	VBP
cord-293938-40zyv1h8	78	26	either	either	CC
cord-293938-40zyv1h8	78	27	transmission	transmission	NN
cord-293938-40zyv1h8	78	28	or	or	CC
cord-293938-40zyv1h8	78	29	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	78	30	.	.	.
cord-293938-40zyv1h8	79	1	It	-PRON-	PRP
cord-293938-40zyv1h8	79	2	's	be	VBZ
cord-293938-40zyv1h8	79	3	also	also	RB
cord-293938-40zyv1h8	79	4	important	important	JJ
cord-293938-40zyv1h8	79	5	to	to	TO
cord-293938-40zyv1h8	79	6	elucidate	elucidate	VB
cord-293938-40zyv1h8	79	7	whether	whether	IN
cord-293938-40zyv1h8	79	8	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	79	9	currently	currently	RB
cord-293938-40zyv1h8	79	10	circulating	circulate	VBG
cord-293938-40zyv1h8	79	11	in	in	IN
cord-293938-40zyv1h8	79	12	animals	animal	NNS
cord-293938-40zyv1h8	79	13	are	be	VBP
cord-293938-40zyv1h8	79	14	a	a	DT
cord-293938-40zyv1h8	79	15	potential	potential	JJ
cord-293938-40zyv1h8	79	16	danger	danger	NN
cord-293938-40zyv1h8	79	17	to	to	IN
cord-293938-40zyv1h8	79	18	the	the	DT
cord-293938-40zyv1h8	79	19	human	human	JJ
cord-293938-40zyv1h8	79	20	population	population	NN
cord-293938-40zyv1h8	79	21	.	.	.
cord-293938-40zyv1h8	80	1	All	all	DT
cord-293938-40zyv1h8	80	2	of	of	IN
cord-293938-40zyv1h8	80	3	the	the	DT
cord-293938-40zyv1h8	80	4	known	know	VBN
cord-293938-40zyv1h8	80	5	cellular	cellular	JJ
cord-293938-40zyv1h8	80	6	receptors	receptor	NNS
cord-293938-40zyv1h8	80	7	of	of	IN
cord-293938-40zyv1h8	80	8	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	80	9	belong	belong	VBP
cord-293938-40zyv1h8	80	10	to	to	IN
cord-293938-40zyv1h8	80	11	the	the	DT
cord-293938-40zyv1h8	80	12	same	same	JJ
cord-293938-40zyv1h8	80	13	protein	protein	NN
cord-293938-40zyv1h8	80	14	family	family	NN
cord-293938-40zyv1h8	80	15	,	,	,
cord-293938-40zyv1h8	80	16	the	the	DT
cord-293938-40zyv1h8	80	17	membrane	membrane	NN
cord-293938-40zyv1h8	80	18	ectopeptidases	ectopeptidase	NNS
cord-293938-40zyv1h8	80	19	.	.	.
cord-293938-40zyv1h8	81	1	Interestingly	interestingly	RB
cord-293938-40zyv1h8	81	2	,	,	,
cord-293938-40zyv1h8	81	3	the	the	DT
cord-293938-40zyv1h8	81	4	catalytic	catalytic	JJ
cord-293938-40zyv1h8	81	5	activity	activity	NN
cord-293938-40zyv1h8	81	6	of	of	IN
cord-293938-40zyv1h8	81	7	these	these	DT
cord-293938-40zyv1h8	81	8	peptidases	peptidase	NNS
cord-293938-40zyv1h8	81	9	is	be	VBZ
cord-293938-40zyv1h8	81	10	not	not	RB
cord-293938-40zyv1h8	81	11	required	require	VBN
cord-293938-40zyv1h8	81	12	for	for	IN
cord-293938-40zyv1h8	81	13	viral	viral	JJ
cord-293938-40zyv1h8	81	14	entry	entry	NN
cord-293938-40zyv1h8	81	15	but	but	CC
cord-293938-40zyv1h8	81	16	rather	rather	RB
cord-293938-40zyv1h8	81	17	the	the	DT
cord-293938-40zyv1h8	81	18	co	co	NN
cord-293938-40zyv1h8	81	19	-	-	NN
cord-293938-40zyv1h8	81	20	expression	expression	NN
cord-293938-40zyv1h8	81	21	of	of	IN
cord-293938-40zyv1h8	81	22	other	other	JJ
cord-293938-40zyv1h8	81	23	host	host	NN
cord-293938-40zyv1h8	81	24	peptidases	peptidase	NNS
cord-293938-40zyv1h8	81	25	activates	activate	VBZ
cord-293938-40zyv1h8	81	26	the	the	DT
cord-293938-40zyv1h8	81	27	HCoV	hcov	NN
cord-293938-40zyv1h8	81	28	spike	spike	NN
cord-293938-40zyv1h8	81	29	proteins	protein	NNS
cord-293938-40zyv1h8	81	30	[	[	-LRB-
cord-293938-40zyv1h8	81	31	42	42	CD
cord-293938-40zyv1h8	81	32	,	,	,
cord-293938-40zyv1h8	81	33	43	43	CD
cord-293938-40zyv1h8	81	34	]	]	-RRB-
cord-293938-40zyv1h8	81	35	.	.	.
cord-293938-40zyv1h8	82	1	It	-PRON-	PRP
cord-293938-40zyv1h8	82	2	has	have	VBZ
cord-293938-40zyv1h8	82	3	been	be	VBN
cord-293938-40zyv1h8	82	4	established	establish	VBN
cord-293938-40zyv1h8	82	5	that	that	IN
cord-293938-40zyv1h8	82	6	the	the	DT
cord-293938-40zyv1h8	82	7	human	human	JJ
cord-293938-40zyv1h8	82	8	transmembrane	transmembrane	NN
cord-293938-40zyv1h8	82	9	serine	serine	NN
cord-293938-40zyv1h8	82	10	proteases	protease	NNS
cord-293938-40zyv1h8	82	11	TMPRSSII	TMPRSSII	NNP
cord-293938-40zyv1h8	82	12	and	and	CC
cord-293938-40zyv1h8	82	13	HAT	HAT	NNP
cord-293938-40zyv1h8	82	14	cleave	cleave	VBP
cord-293938-40zyv1h8	82	15	and	and	CC
cord-293938-40zyv1h8	82	16	activate	activate	VBP
cord-293938-40zyv1h8	82	17	the	the	DT
cord-293938-40zyv1h8	82	18	HCoV-229E	HCoV-229E	NNP
cord-293938-40zyv1h8	82	19	,	,	,
cord-293938-40zyv1h8	82	20	SARS	SARS	NNP
cord-293938-40zyv1h8	82	21	-	-	:
cord-293938-40zyv1h8	82	22	and	and	CC
cord-293938-40zyv1h8	82	23	MERS	MERS	NNP
cord-293938-40zyv1h8	82	24	-	-	HYPH
cord-293938-40zyv1h8	82	25	CoV	cov	NN
cord-293938-40zyv1h8	82	26	spike	spike	NN
cord-293938-40zyv1h8	82	27	proteins	protein	NNS
cord-293938-40zyv1h8	82	28	during	during	IN
cord-293938-40zyv1h8	82	29	viral	viral	JJ
cord-293938-40zyv1h8	82	30	entry	entry	NN
cord-293938-40zyv1h8	82	31	[	[	-LRB-
cord-293938-40zyv1h8	82	32	44	44	CD
cord-293938-40zyv1h8	82	33	,	,	,
cord-293938-40zyv1h8	82	34	45	45	CD
cord-293938-40zyv1h8	82	35	]	]	-RRB-
cord-293938-40zyv1h8	82	36	.	.	.
cord-293938-40zyv1h8	83	1	Out	out	IN
cord-293938-40zyv1h8	83	2	of	of	IN
cord-293938-40zyv1h8	83	3	the	the	DT
cord-293938-40zyv1h8	83	4	four	four	CD
cord-293938-40zyv1h8	83	5	commonly	commonly	RB
cord-293938-40zyv1h8	83	6	circulating	circulate	VBG
cord-293938-40zyv1h8	83	7	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	83	8	,	,	,
cord-293938-40zyv1h8	83	9	HCoV-229E	HCoV-229E	NNP
cord-293938-40zyv1h8	83	10	is	be	VBZ
cord-293938-40zyv1h8	83	11	the	the	DT
cord-293938-40zyv1h8	83	12	only	only	JJ
cord-293938-40zyv1h8	83	13	one	one	CD
cord-293938-40zyv1h8	83	14	that	that	WDT
cord-293938-40zyv1h8	83	15	infects	infect	VBZ
cord-293938-40zyv1h8	83	16	non	non	JJ
cord-293938-40zyv1h8	83	17	-	-	JJ
cord-293938-40zyv1h8	83	18	ciliated	ciliated	JJ
cord-293938-40zyv1h8	83	19	cells	cell	NNS
cord-293938-40zyv1h8	83	20	using	use	VBG
cord-293938-40zyv1h8	83	21	the	the	DT
cord-293938-40zyv1h8	83	22	human	human	JJ
cord-293938-40zyv1h8	83	23	Aminopeptidase	Aminopeptidase	NNP
cord-293938-40zyv1h8	83	24	N	N	NNP
cord-293938-40zyv1h8	83	25	(	(	-LRB-
cord-293938-40zyv1h8	83	26	hAPN	hapn	NN
cord-293938-40zyv1h8	83	27	)	)	-RRB-
cord-293938-40zyv1h8	83	28	as	as	IN
cord-293938-40zyv1h8	83	29	its	-PRON-	PRP$
cord-293938-40zyv1h8	83	30	receptor	receptor	NN
cord-293938-40zyv1h8	83	31	[	[	-LRB-
cord-293938-40zyv1h8	83	32	46	46	CD
cord-293938-40zyv1h8	83	33	]	]	-RRB-
cord-293938-40zyv1h8	83	34	.	.	.
cord-293938-40zyv1h8	84	1	This	this	DT
cord-293938-40zyv1h8	84	2	peptidase	peptidase	NN
cord-293938-40zyv1h8	84	3	is	be	VBZ
cord-293938-40zyv1h8	84	4	predominantly	predominantly	RB
cord-293938-40zyv1h8	84	5	expressed	express	VBN
cord-293938-40zyv1h8	84	6	on	on	IN
cord-293938-40zyv1h8	84	7	non	non	JJ
cord-293938-40zyv1h8	84	8	-	-	JJ
cord-293938-40zyv1h8	84	9	ciliated	ciliated	JJ
cord-293938-40zyv1h8	84	10	cells	cell	NNS
cord-293938-40zyv1h8	84	11	in	in	IN
cord-293938-40zyv1h8	84	12	the	the	DT
cord-293938-40zyv1h8	84	13	human	human	JJ
cord-293938-40zyv1h8	84	14	bronchus	bronchus	NN
cord-293938-40zyv1h8	84	15	[	[	-LRB-
cord-293938-40zyv1h8	84	16	47	47	CD
cord-293938-40zyv1h8	84	17	]	]	-RRB-
cord-293938-40zyv1h8	84	18	.	.	.
cord-293938-40zyv1h8	85	1	SARS	SARS	NNP
cord-293938-40zyv1h8	85	2	-	-	HYPH
cord-293938-40zyv1h8	85	3	CoV	CoV	NNP
cord-293938-40zyv1h8	85	4	and	and	CC
cord-293938-40zyv1h8	85	5	HCoV	HCoV	NNP
cord-293938-40zyv1h8	86	1	-NL63	-NL63	:
cord-293938-40zyv1h8	86	2	both	both	DT
cord-293938-40zyv1h8	86	3	utilize	utilize	VB
cord-293938-40zyv1h8	86	4	the	the	DT
cord-293938-40zyv1h8	86	5	Angiotensin	Angiotensin	NNP
cord-293938-40zyv1h8	86	6	Converting	Converting	NNP
cord-293938-40zyv1h8	86	7	Enzyme	Enzyme	NNP
cord-293938-40zyv1h8	86	8	2	2	CD
cord-293938-40zyv1h8	86	9	(	(	-LRB-
cord-293938-40zyv1h8	86	10	ACE2	ACE2	NNP
cord-293938-40zyv1h8	86	11	)	)	-RRB-
cord-293938-40zyv1h8	86	12	for	for	IN
cord-293938-40zyv1h8	86	13	cellular	cellular	JJ
cord-293938-40zyv1h8	86	14	binding	binding	NN
cord-293938-40zyv1h8	86	15	[	[	-LRB-
cord-293938-40zyv1h8	86	16	48	48	CD
cord-293938-40zyv1h8	86	17	,	,	,
cord-293938-40zyv1h8	86	18	49	49	CD
cord-293938-40zyv1h8	86	19	]	]	-RRB-
cord-293938-40zyv1h8	86	20	.	.	.
cord-293938-40zyv1h8	87	1	ACE2	ACE2	NNP
cord-293938-40zyv1h8	87	2	is	be	VBZ
cord-293938-40zyv1h8	87	3	expressed	express	VBN
cord-293938-40zyv1h8	87	4	on	on	IN
cord-293938-40zyv1h8	87	5	ciliated	ciliated	JJ
cord-293938-40zyv1h8	87	6	bronchial	bronchial	JJ
cord-293938-40zyv1h8	87	7	cells	cell	NNS
cord-293938-40zyv1h8	87	8	along	along	IN
cord-293938-40zyv1h8	87	9	with	with	IN
cord-293938-40zyv1h8	87	10	endothelial	endothelial	JJ
cord-293938-40zyv1h8	87	11	cells	cell	NNS
cord-293938-40zyv1h8	87	12	and	and	CC
cord-293938-40zyv1h8	87	13	both	both	DT
cord-293938-40zyv1h8	87	14	type	type	NN
cord-293938-40zyv1h8	87	15	I	-PRON-	PRP
cord-293938-40zyv1h8	87	16	and	and	CC
cord-293938-40zyv1h8	87	17	II	ii	CD
cord-293938-40zyv1h8	87	18	alveolar	alveolar	NN
cord-293938-40zyv1h8	87	19	cells	cell	NNS
cord-293938-40zyv1h8	87	20	[	[	-LRB-
cord-293938-40zyv1h8	87	21	50	50	CD
cord-293938-40zyv1h8	87	22	]	]	-RRB-
cord-293938-40zyv1h8	87	23	.	.	.
cord-293938-40zyv1h8	88	1	MERS	MERS	NNP
cord-293938-40zyv1h8	88	2	-	-	HYPH
cord-293938-40zyv1h8	88	3	CoV	CoV	NNP
cord-293938-40zyv1h8	88	4	was	be	VBD
cord-293938-40zyv1h8	88	5	found	find	VBN
cord-293938-40zyv1h8	88	6	to	to	TO
cord-293938-40zyv1h8	88	7	use	use	VB
cord-293938-40zyv1h8	88	8	a	a	DT
cord-293938-40zyv1h8	88	9	different	different	JJ
cord-293938-40zyv1h8	88	10	receptor	receptor	NN
cord-293938-40zyv1h8	88	11	than	than	IN
cord-293938-40zyv1h8	88	12	SARS	SARS	NNP
cord-293938-40zyv1h8	88	13	-	-	HYPH
cord-293938-40zyv1h8	88	14	CoV	CoV	NNP
cord-293938-40zyv1h8	88	15	,	,	,
cord-293938-40zyv1h8	88	16	namely	namely	RB
cord-293938-40zyv1h8	88	17	the	the	DT
cord-293938-40zyv1h8	88	18	dipeptyl	dipeptyl	NN
cord-293938-40zyv1h8	88	19	-	-	HYPH
cord-293938-40zyv1h8	88	20	peptidase	peptidase	NN
cord-293938-40zyv1h8	88	21	4	4	CD
cord-293938-40zyv1h8	88	22	(	(	-LRB-
cord-293938-40zyv1h8	88	23	DPP4	DPP4	NNP
cord-293938-40zyv1h8	88	24	)	)	-RRB-
cord-293938-40zyv1h8	88	25	[	[	-LRB-
cord-293938-40zyv1h8	88	26	51	51	CD
cord-293938-40zyv1h8	88	27	]	]	-RRB-
cord-293938-40zyv1h8	88	28	.	.	.
cord-293938-40zyv1h8	89	1	DPP4	DPP4	NNP
cord-293938-40zyv1h8	89	2	is	be	VBZ
cord-293938-40zyv1h8	89	3	widely	widely	RB
cord-293938-40zyv1h8	89	4	expressed	express	VBN
cord-293938-40zyv1h8	89	5	in	in	IN
cord-293938-40zyv1h8	89	6	endothelial	endothelial	JJ
cord-293938-40zyv1h8	89	7	cells	cell	NNS
cord-293938-40zyv1h8	89	8	and	and	CC
cord-293938-40zyv1h8	89	9	various	various	JJ
cord-293938-40zyv1h8	89	10	epithelial	epithelial	JJ
cord-293938-40zyv1h8	89	11	tissues	tissue	NNS
cord-293938-40zyv1h8	89	12	in	in	IN
cord-293938-40zyv1h8	89	13	the	the	DT
cord-293938-40zyv1h8	89	14	human	human	JJ
cord-293938-40zyv1h8	89	15	body	body	NN
cord-293938-40zyv1h8	89	16	[	[	-LRB-
cord-293938-40zyv1h8	89	17	52	52	CD
cord-293938-40zyv1h8	89	18	]	]	-RRB-
cord-293938-40zyv1h8	89	19	.	.	.
cord-293938-40zyv1h8	90	1	In	in	IN
cord-293938-40zyv1h8	90	2	ex	ex	FW
cord-293938-40zyv1h8	90	3	vivo	vivo	NNP
cord-293938-40zyv1h8	90	4	human	human	JJ
cord-293938-40zyv1h8	90	5	lung	lung	NN
cord-293938-40zyv1h8	90	6	organ	organ	NN
cord-293938-40zyv1h8	90	7	cultures	culture	NNS
cord-293938-40zyv1h8	90	8	,	,	,
cord-293938-40zyv1h8	90	9	different	different	JJ
cord-293938-40zyv1h8	90	10	tropism	tropism	NN
cord-293938-40zyv1h8	90	11	of	of	IN
cord-293938-40zyv1h8	90	12	SARS	SARS	NNP
cord-293938-40zyv1h8	90	13	-	-	:
cord-293938-40zyv1h8	90	14	and	and	CC
cord-293938-40zyv1h8	90	15	MERS	MERS	NNP
cord-293938-40zyv1h8	90	16	-	-	HYPH
cord-293938-40zyv1h8	90	17	CoVs	CoVs	NNP
cord-293938-40zyv1h8	90	18	was	be	VBD
cord-293938-40zyv1h8	90	19	observed	observe	VBN
cord-293938-40zyv1h8	90	20	.	.	.
cord-293938-40zyv1h8	91	1	MERS	MERS	NNP
cord-293938-40zyv1h8	91	2	-	-	HYPH
cord-293938-40zyv1h8	91	3	CoV	CoV	NNP
cord-293938-40zyv1h8	91	4	can	can	MD
cord-293938-40zyv1h8	91	5	actively	actively	RB
cord-293938-40zyv1h8	91	6	replicate	replicate	VB
cord-293938-40zyv1h8	91	7	in	in	IN
cord-293938-40zyv1h8	91	8	both	both	CC
cord-293938-40zyv1h8	91	9	bronchial	bronchial	JJ
cord-293938-40zyv1h8	91	10	and	and	CC
cord-293938-40zyv1h8	91	11	alveolar	alveolar	JJ
cord-293938-40zyv1h8	91	12	tissue	tissue	NN
cord-293938-40zyv1h8	91	13	while	while	IN
cord-293938-40zyv1h8	91	14	SARS	SARS	NNP
cord-293938-40zyv1h8	91	15	-	-	HYPH
cord-293938-40zyv1h8	91	16	CoV	CoV	NNP
cord-293938-40zyv1h8	91	17	primarily	primarily	RB
cord-293938-40zyv1h8	91	18	replicates	replicate	VBZ
cord-293938-40zyv1h8	91	19	in	in	IN
cord-293938-40zyv1h8	91	20	alveolar	alveolar	JJ
cord-293938-40zyv1h8	91	21	tissue	tissue	NN
cord-293938-40zyv1h8	91	22	[	[	-LRB-
cord-293938-40zyv1h8	91	23	53	53	CD
cord-293938-40zyv1h8	91	24	]	]	-RRB-
cord-293938-40zyv1h8	91	25	.	.	.
cord-293938-40zyv1h8	92	1	The	the	DT
cord-293938-40zyv1h8	92	2	wide	wide	JJ
cord-293938-40zyv1h8	92	3	cellular	cellular	JJ
cord-293938-40zyv1h8	92	4	tropism	tropism	NN
cord-293938-40zyv1h8	92	5	of	of	IN
cord-293938-40zyv1h8	92	6	MERS	MERS	NNP
cord-293938-40zyv1h8	92	7	-	-	HYPH
cord-293938-40zyv1h8	92	8	CoV	CoV	NNP
cord-293938-40zyv1h8	92	9	might	may	MD
cord-293938-40zyv1h8	92	10	contribute	contribute	VB
cord-293938-40zyv1h8	92	11	to	to	IN
cord-293938-40zyv1h8	92	12	its	-PRON-	PRP$
cord-293938-40zyv1h8	92	13	associated	associated	JJ
cord-293938-40zyv1h8	92	14	disease	disease	NN
cord-293938-40zyv1h8	92	15	severity	severity	NN
cord-293938-40zyv1h8	92	16	and	and	CC
cord-293938-40zyv1h8	92	17	high	high	JJ
cord-293938-40zyv1h8	92	18	mortality	mortality	NN
cord-293938-40zyv1h8	92	19	rate	rate	NN
cord-293938-40zyv1h8	92	20	whereas	whereas	IN
cord-293938-40zyv1h8	92	21	the	the	DT
cord-293938-40zyv1h8	92	22	alveolar	alveolar	JJ
cord-293938-40zyv1h8	92	23	replication	replication	NN
cord-293938-40zyv1h8	92	24	of	of	IN
cord-293938-40zyv1h8	92	25	SARS	SARS	NNP
cord-293938-40zyv1h8	92	26	-	-	HYPH
cord-293938-40zyv1h8	92	27	CoV	CoV	NNP
cord-293938-40zyv1h8	92	28	would	would	MD
cord-293938-40zyv1h8	92	29	explain	explain	VB
cord-293938-40zyv1h8	92	30	why	why	WRB
cord-293938-40zyv1h8	92	31	it	-PRON-	PRP
cord-293938-40zyv1h8	92	32	generally	generally	RB
cord-293938-40zyv1h8	92	33	presents	present	VBZ
cord-293938-40zyv1h8	92	34	with	with	IN
cord-293938-40zyv1h8	92	35	pneumonia	pneumonia	NN
cord-293938-40zyv1h8	92	36	.	.	.
cord-293938-40zyv1h8	93	1	The	the	DT
cord-293938-40zyv1h8	93	2	cellular	cellular	JJ
cord-293938-40zyv1h8	93	3	surface	surface	NN
cord-293938-40zyv1h8	93	4	receptors	receptor	NNS
cord-293938-40zyv1h8	93	5	for	for	IN
cord-293938-40zyv1h8	93	6	HCoV	HCoV	NNP
cord-293938-40zyv1h8	93	7	-	-	HYPH
cord-293938-40zyv1h8	93	8	OC43	OC43	NNP
cord-293938-40zyv1h8	93	9	and	and	CC
cord-293938-40zyv1h8	93	10	HCoV	HCoV	NNP
cord-293938-40zyv1h8	93	11	-	-	HYPH
cord-293938-40zyv1h8	93	12	HKU1	HKU1	NNP
cord-293938-40zyv1h8	93	13	are	be	VBP
cord-293938-40zyv1h8	93	14	currently	currently	RB
cord-293938-40zyv1h8	93	15	unknown	unknown	JJ
cord-293938-40zyv1h8	93	16	but	but	CC
cord-293938-40zyv1h8	93	17	receptor	receptor	NN
cord-293938-40zyv1h8	93	18	determinants	determinant	NNS
cord-293938-40zyv1h8	93	19	for	for	IN
cord-293938-40zyv1h8	93	20	these	these	DT
cord-293938-40zyv1h8	93	21	two	two	CD
cord-293938-40zyv1h8	93	22	viruses	virus	NNS
cord-293938-40zyv1h8	93	23	have	have	VBP
cord-293938-40zyv1h8	93	24	been	be	VBN
cord-293938-40zyv1h8	93	25	identified	identify	VBN
cord-293938-40zyv1h8	93	26	as	as	IN
cord-293938-40zyv1h8	93	27	N	n	CD
cord-293938-40zyv1h8	93	28	-	-	HYPH
cord-293938-40zyv1h8	93	29	acetyl-9-O	acetyl-9-o	NN
cord-293938-40zyv1h8	93	30	-	-	HYPH
cord-293938-40zyv1h8	93	31	acetylneuraminic	acetylneuraminic	JJ
cord-293938-40zyv1h8	93	32	acid	acid	NN
cord-293938-40zyv1h8	93	33	and	and	CC
cord-293938-40zyv1h8	93	34	O	O	NNP
cord-293938-40zyv1h8	93	35	-	-	HYPH
cord-293938-40zyv1h8	93	36	Acetylated	Acetylated	NNP
cord-293938-40zyv1h8	93	37	Sialic	Sialic	NNP
cord-293938-40zyv1h8	93	38	acid	acid	NN
cord-293938-40zyv1h8	93	39	,	,	,
cord-293938-40zyv1h8	93	40	respectively	respectively	RB
cord-293938-40zyv1h8	93	41	[	[	-LRB-
cord-293938-40zyv1h8	93	42	54	54	CD
cord-293938-40zyv1h8	93	43	,	,	,
cord-293938-40zyv1h8	93	44	55	55	CD
cord-293938-40zyv1h8	93	45	]	]	-RRB-
cord-293938-40zyv1h8	93	46	.	.	.
cord-293938-40zyv1h8	94	1	All	all	DT
cord-293938-40zyv1h8	94	2	of	of	IN
cord-293938-40zyv1h8	94	3	these	these	DT
cord-293938-40zyv1h8	94	4	viruses	virus	NNS
cord-293938-40zyv1h8	94	5	can	can	MD
cord-293938-40zyv1h8	94	6	be	be	VB
cord-293938-40zyv1h8	94	7	successfully	successfully	RB
cord-293938-40zyv1h8	94	8	cultured	culture	VBN
cord-293938-40zyv1h8	94	9	and	and	CC
cord-293938-40zyv1h8	94	10	investigated	investigate	VBN
cord-293938-40zyv1h8	94	11	in	in	IN
cord-293938-40zyv1h8	94	12	HAE	HAE	NNP
cord-293938-40zyv1h8	94	13	cultures	culture	NNS
cord-293938-40zyv1h8	94	14	[	[	-LRB-
cord-293938-40zyv1h8	94	15	56	56	CD
cord-293938-40zyv1h8	94	16	,	,	,
cord-293938-40zyv1h8	94	17	57	57	CD
cord-293938-40zyv1h8	94	18	]	]	-RRB-
cord-293938-40zyv1h8	94	19	.	.	.
cord-293938-40zyv1h8	95	1	The	the	DT
cord-293938-40zyv1h8	95	2	discovery	discovery	NN
cord-293938-40zyv1h8	95	3	of	of	IN
cord-293938-40zyv1h8	95	4	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	95	5	,	,	,
cord-293938-40zyv1h8	95	6	their	-PRON-	PRP$
cord-293938-40zyv1h8	95	7	receptor	receptor	NN
cord-293938-40zyv1h8	95	8	usage	usage	NN
cord-293938-40zyv1h8	95	9	,	,	,
cord-293938-40zyv1h8	95	10	cell	cell	NN
cord-293938-40zyv1h8	95	11	tropism	tropism	NN
cord-293938-40zyv1h8	95	12	and	and	CC
cord-293938-40zyv1h8	95	13	receptor	receptor	NN
cord-293938-40zyv1h8	95	14	binding	bind	VBG
cord-293938-40zyv1h8	95	15	domain	domain	NN
cord-293938-40zyv1h8	95	16	(	(	-LRB-
cord-293938-40zyv1h8	95	17	RBD	RBD	NNP
cord-293938-40zyv1h8	95	18	)	)	-RRB-
cord-293938-40zyv1h8	95	19	is	be	VBZ
cord-293938-40zyv1h8	95	20	summarized	summarize	VBN
cord-293938-40zyv1h8	95	21	in	in	IN
cord-293938-40zyv1h8	95	22	Table	Table	NNP
cord-293938-40zyv1h8	95	23	1	1	CD
cord-293938-40zyv1h8	95	24	.	.	.
cord-293938-40zyv1h8	96	1	Furthermore	furthermore	RB
cord-293938-40zyv1h8	96	2	,	,	,
cord-293938-40zyv1h8	96	3	established	establish	VBN
cord-293938-40zyv1h8	96	4	reverse	reverse	JJ
cord-293938-40zyv1h8	96	5	genetic	genetic	JJ
cord-293938-40zyv1h8	96	6	systems	system	NNS
cord-293938-40zyv1h8	96	7	for	for	IN
cord-293938-40zyv1h8	96	8	HCoV-229E	HCoV-229E	NNP
cord-293938-40zyv1h8	96	9	[	[	-LRB-
cord-293938-40zyv1h8	96	10	58	58	CD
cord-293938-40zyv1h8	96	11	]	]	-RRB-
cord-293938-40zyv1h8	96	12	,	,	,
cord-293938-40zyv1h8	96	13	HCoV	HCoV	NNP
cord-293938-40zyv1h8	96	14	-	-	HYPH
cord-293938-40zyv1h8	96	15	OC43	OC43	NNP
cord-293938-40zyv1h8	96	16	[	[	-LRB-
cord-293938-40zyv1h8	96	17	59	59	CD
cord-293938-40zyv1h8	96	18	]	]	-RRB-
cord-293938-40zyv1h8	96	19	and	and	CC
cord-293938-40zyv1h8	97	1	HCoV	HCoV	NNP
cord-293938-40zyv1h8	98	1	-NL63	-NL63	:
cord-293938-40zyv1h8	99	1	[	[	-LRB-
cord-293938-40zyv1h8	99	2	60	60	CD
cord-293938-40zyv1h8	99	3	]	]	-RRB-
cord-293938-40zyv1h8	99	4	allow	allow	VB
cord-293938-40zyv1h8	99	5	for	for	IN
cord-293938-40zyv1h8	99	6	controlled	control	VBN
cord-293938-40zyv1h8	99	7	virus	virus	NN
cord-293938-40zyv1h8	99	8	mutation	mutation	NN
cord-293938-40zyv1h8	99	9	and	and	CC
cord-293938-40zyv1h8	99	10	fluorescent	fluorescent	NN
cord-293938-40zyv1h8	99	11	transgene	transgene	NN
cord-293938-40zyv1h8	99	12	insertion	insertion	NN
cord-293938-40zyv1h8	99	13	to	to	TO
cord-293938-40zyv1h8	99	14	better	better	RB
cord-293938-40zyv1h8	99	15	understand	understand	VB
cord-293938-40zyv1h8	99	16	the	the	DT
cord-293938-40zyv1h8	99	17	interaction	interaction	NN
cord-293938-40zyv1h8	99	18	of	of	IN
cord-293938-40zyv1h8	99	19	these	these	DT
cord-293938-40zyv1h8	99	20	viruses	virus	NNS
cord-293938-40zyv1h8	99	21	with	with	IN
cord-293938-40zyv1h8	99	22	their	-PRON-	PRP$
cord-293938-40zyv1h8	99	23	pulmonary	pulmonary	JJ
cord-293938-40zyv1h8	99	24	host	host	NN
cord-293938-40zyv1h8	99	25	cells	cell	NNS
cord-293938-40zyv1h8	99	26	.	.	.
cord-293938-40zyv1h8	100	1	Traditionally	traditionally	RB
cord-293938-40zyv1h8	100	2	,	,	,
cord-293938-40zyv1h8	100	3	respiratory	respiratory	JJ
cord-293938-40zyv1h8	100	4	viruses	virus	NNS
cord-293938-40zyv1h8	100	5	are	be	VBP
cord-293938-40zyv1h8	100	6	studied	study	VBN
cord-293938-40zyv1h8	100	7	in	in	IN
cord-293938-40zyv1h8	100	8	animal	animal	NN
cord-293938-40zyv1h8	100	9	models	model	NNS
cord-293938-40zyv1h8	100	10	,	,	,
cord-293938-40zyv1h8	100	11	usually	usually	RB
cord-293938-40zyv1h8	100	12	mice	mouse	NNS
cord-293938-40zyv1h8	100	13	and	and	CC
cord-293938-40zyv1h8	100	14	ferrets	ferret	NNS
cord-293938-40zyv1h8	100	15	[	[	-LRB-
cord-293938-40zyv1h8	100	16	48	48	CD
cord-293938-40zyv1h8	100	17	,	,	,
cord-293938-40zyv1h8	100	18	61	61	CD
cord-293938-40zyv1h8	100	19	]	]	-RRB-
cord-293938-40zyv1h8	100	20	.	.	.
cord-293938-40zyv1h8	101	1	However	however	RB
cord-293938-40zyv1h8	101	2	,	,	,
cord-293938-40zyv1h8	101	3	it	-PRON-	PRP
cord-293938-40zyv1h8	101	4	is	be	VBZ
cord-293938-40zyv1h8	101	5	not	not	RB
cord-293938-40zyv1h8	101	6	always	always	RB
cord-293938-40zyv1h8	101	7	possible	possible	JJ
cord-293938-40zyv1h8	101	8	to	to	TO
cord-293938-40zyv1h8	101	9	correctly	correctly	RB
cord-293938-40zyv1h8	101	10	recapitulate	recapitulate	VB
cord-293938-40zyv1h8	101	11	human	human	JJ
cord-293938-40zyv1h8	101	12	infection	infection	NN
cord-293938-40zyv1h8	101	13	and	and	CC
cord-293938-40zyv1h8	101	14	disease	disease	NN
cord-293938-40zyv1h8	101	15	in	in	IN
cord-293938-40zyv1h8	101	16	animal	animal	NN
cord-293938-40zyv1h8	101	17	models	model	NNS
cord-293938-40zyv1h8	101	18	.	.	.
cord-293938-40zyv1h8	102	1	The	the	DT
cord-293938-40zyv1h8	102	2	establishment	establishment	NN
cord-293938-40zyv1h8	102	3	of	of	IN
cord-293938-40zyv1h8	102	4	transgenic	transgenic	JJ
cord-293938-40zyv1h8	102	5	animal	animal	NN
cord-293938-40zyv1h8	102	6	models	model	NNS
cord-293938-40zyv1h8	102	7	for	for	IN
cord-293938-40zyv1h8	102	8	human	human	JJ
cord-293938-40zyv1h8	102	9	disease	disease	NN
cord-293938-40zyv1h8	102	10	is	be	VBZ
cord-293938-40zyv1h8	102	11	attainable	attainable	JJ
cord-293938-40zyv1h8	102	12	when	when	WRB
cord-293938-40zyv1h8	102	13	either	either	CC
cord-293938-40zyv1h8	102	14	the	the	DT
cord-293938-40zyv1h8	102	15	virus	virus	NN
cord-293938-40zyv1h8	102	16	receptor	receptor	NN
cord-293938-40zyv1h8	102	17	has	have	VBZ
cord-293938-40zyv1h8	102	18	been	be	VBN
cord-293938-40zyv1h8	102	19	identified	identify	VBN
cord-293938-40zyv1h8	102	20	,	,	,
cord-293938-40zyv1h8	102	21	which	which	WDT
cord-293938-40zyv1h8	102	22	is	be	VBZ
cord-293938-40zyv1h8	102	23	not	not	RB
cord-293938-40zyv1h8	102	24	the	the	DT
cord-293938-40zyv1h8	102	25	case	case	NN
cord-293938-40zyv1h8	102	26	for	for	IN
cord-293938-40zyv1h8	102	27	all	all	DT
cord-293938-40zyv1h8	102	28	HCoVs	hcovs	CD
cord-293938-40zyv1h8	102	29	,	,	,
cord-293938-40zyv1h8	102	30	or	or	CC
cord-293938-40zyv1h8	102	31	when	when	WRB
cord-293938-40zyv1h8	102	32	viruses	virus	NNS
cord-293938-40zyv1h8	102	33	can	can	MD
cord-293938-40zyv1h8	102	34	be	be	VB
cord-293938-40zyv1h8	102	35	adapted	adapt	VBN
cord-293938-40zyv1h8	102	36	to	to	IN
cord-293938-40zyv1h8	102	37	a	a	DT
cord-293938-40zyv1h8	102	38	different	different	JJ
cord-293938-40zyv1h8	102	39	host	host	NN
cord-293938-40zyv1h8	102	40	.	.	.
cord-293938-40zyv1h8	103	1	An	an	DT
cord-293938-40zyv1h8	103	2	adapted	adapt	VBN
cord-293938-40zyv1h8	103	3	human	human	JJ
cord-293938-40zyv1h8	103	4	virus	virus	NN
cord-293938-40zyv1h8	103	5	may	may	MD
cord-293938-40zyv1h8	103	6	not	not	RB
cord-293938-40zyv1h8	103	7	share	share	VB
cord-293938-40zyv1h8	103	8	the	the	DT
cord-293938-40zyv1h8	103	9	same	same	JJ
cord-293938-40zyv1h8	103	10	properties	property	NNS
cord-293938-40zyv1h8	103	11	as	as	IN
cord-293938-40zyv1h8	103	12	the	the	DT
cord-293938-40zyv1h8	103	13	original	original	JJ
cord-293938-40zyv1h8	103	14	human	human	JJ
cord-293938-40zyv1h8	103	15	virus	virus	NN
cord-293938-40zyv1h8	103	16	.	.	.
cord-293938-40zyv1h8	104	1	SARS	SARS	NNP
cord-293938-40zyv1h8	104	2	-	-	HYPH
cord-293938-40zyv1h8	104	3	CoV	CoV	NNP
cord-293938-40zyv1h8	104	4	was	be	VBD
cord-293938-40zyv1h8	104	5	found	find	VBN
cord-293938-40zyv1h8	104	6	to	to	TO
cord-293938-40zyv1h8	104	7	replicate	replicate	VB
cord-293938-40zyv1h8	104	8	naturally	naturally	RB
cord-293938-40zyv1h8	104	9	in	in	IN
cord-293938-40zyv1h8	104	10	various	various	JJ
cord-293938-40zyv1h8	104	11	strains	strain	NNS
cord-293938-40zyv1h8	104	12	of	of	IN
cord-293938-40zyv1h8	104	13	inbred	inbred	JJ
cord-293938-40zyv1h8	104	14	mice	mouse	NNS
cord-293938-40zyv1h8	104	15	but	but	CC
cord-293938-40zyv1h8	104	16	to	to	TO
cord-293938-40zyv1h8	104	17	enhance	enhance	VB
cord-293938-40zyv1h8	104	18	clinical	clinical	JJ
cord-293938-40zyv1h8	104	19	signs	sign	NNS
cord-293938-40zyv1h8	104	20	of	of	IN
cord-293938-40zyv1h8	104	21	disease	disease	NN
cord-293938-40zyv1h8	104	22	the	the	DT
cord-293938-40zyv1h8	104	23	hACE2	hace2	NN
cord-293938-40zyv1h8	104	24	was	be	VBD
cord-293938-40zyv1h8	104	25	introduced	introduce	VBN
cord-293938-40zyv1h8	104	26	into	into	IN
cord-293938-40zyv1h8	104	27	these	these	DT
cord-293938-40zyv1h8	104	28	mice	mouse	NNS
cord-293938-40zyv1h8	104	29	.	.	.
cord-293938-40zyv1h8	105	1	This	this	DT
cord-293938-40zyv1h8	105	2	resulted	result	VBD
cord-293938-40zyv1h8	105	3	in	in	IN
cord-293938-40zyv1h8	105	4	murine	murine	JJ
cord-293938-40zyv1h8	105	5	models	model	NNS
cord-293938-40zyv1h8	105	6	with	with	IN
cord-293938-40zyv1h8	105	7	varying	vary	VBG
cord-293938-40zyv1h8	105	8	degree	degree	NN
cord-293938-40zyv1h8	105	9	of	of	IN
cord-293938-40zyv1h8	105	10	human	human	JJ
cord-293938-40zyv1h8	105	11	disease	disease	NN
cord-293938-40zyv1h8	105	12	similarity	similarity	NN
cord-293938-40zyv1h8	105	13	.	.	.
cord-293938-40zyv1h8	106	1	Since	since	IN
cord-293938-40zyv1h8	106	2	SARS	SARS	NNP
cord-293938-40zyv1h8	106	3	-	-	HYPH
cord-293938-40zyv1h8	106	4	CoV	CoV	NNP
cord-293938-40zyv1h8	106	5	already	already	RB
cord-293938-40zyv1h8	106	6	replicated	replicate	VBD
cord-293938-40zyv1h8	106	7	in	in	IN
cord-293938-40zyv1h8	106	8	mouse	mouse	NN
cord-293938-40zyv1h8	106	9	cells	cell	NNS
cord-293938-40zyv1h8	106	10	,	,	,
cord-293938-40zyv1h8	106	11	adapting	adapt	VBG
cord-293938-40zyv1h8	106	12	it	-PRON-	PRP
cord-293938-40zyv1h8	106	13	to	to	IN
cord-293938-40zyv1h8	106	14	the	the	DT
cord-293938-40zyv1h8	106	15	murine	murine	JJ
cord-293938-40zyv1h8	106	16	host	host	NN
cord-293938-40zyv1h8	106	17	was	be	VBD
cord-293938-40zyv1h8	106	18	quite	quite	RB
cord-293938-40zyv1h8	106	19	successful	successful	JJ
cord-293938-40zyv1h8	106	20	.	.	.
cord-293938-40zyv1h8	107	1	This	this	DT
cord-293938-40zyv1h8	107	2	resulted	result	VBD
cord-293938-40zyv1h8	107	3	in	in	IN
cord-293938-40zyv1h8	107	4	three	three	CD
cord-293938-40zyv1h8	107	5	mouse	mouse	NN
cord-293938-40zyv1h8	107	6	adapted	adapt	VBD
cord-293938-40zyv1h8	107	7	strains	strain	NNS
cord-293938-40zyv1h8	107	8	that	that	WDT
cord-293938-40zyv1h8	107	9	caused	cause	VBD
cord-293938-40zyv1h8	107	10	disease	disease	NN
cord-293938-40zyv1h8	107	11	in	in	IN
cord-293938-40zyv1h8	107	12	mice	mouse	NNS
cord-293938-40zyv1h8	107	13	similar	similar	JJ
cord-293938-40zyv1h8	107	14	to	to	IN
cord-293938-40zyv1h8	107	15	severe	severe	JJ
cord-293938-40zyv1h8	107	16	SARS	SARS	NNP
cord-293938-40zyv1h8	107	17	-	-	HYPH
cord-293938-40zyv1h8	107	18	CoV	cov	NN
cord-293938-40zyv1h8	107	19	cases	case	NNS
cord-293938-40zyv1h8	107	20	in	in	IN
cord-293938-40zyv1h8	107	21	humans	human	NNS
cord-293938-40zyv1h8	107	22	[	[	-LRB-
cord-293938-40zyv1h8	107	23	62	62	CD
cord-293938-40zyv1h8	107	24	]	]	-RRB-
cord-293938-40zyv1h8	107	25	.	.	.
cord-293938-40zyv1h8	108	1	In	in	IN
cord-293938-40zyv1h8	108	2	an	an	DT
cord-293938-40zyv1h8	108	3	effort	effort	NN
cord-293938-40zyv1h8	108	4	to	to	TO
cord-293938-40zyv1h8	108	5	establish	establish	VB
cord-293938-40zyv1h8	108	6	a	a	DT
cord-293938-40zyv1h8	108	7	mouse	mouse	NN
cord-293938-40zyv1h8	108	8	model	model	NN
cord-293938-40zyv1h8	108	9	for	for	IN
cord-293938-40zyv1h8	108	10	HCoV-229E	HCoV-229E	NNP
cord-293938-40zyv1h8	108	11	infection	infection	NN
cord-293938-40zyv1h8	108	12	transgenic	transgenic	JJ
cord-293938-40zyv1h8	108	13	hAPN	hapn	NN
cord-293938-40zyv1h8	108	14	mice	mouse	NNS
cord-293938-40zyv1h8	108	15	were	be	VBD
cord-293938-40zyv1h8	108	16	created	create	VBN
cord-293938-40zyv1h8	108	17	.	.	.
cord-293938-40zyv1h8	109	1	However	however	RB
cord-293938-40zyv1h8	109	2	,	,	,
cord-293938-40zyv1h8	109	3	the	the	DT
cord-293938-40zyv1h8	109	4	insertion	insertion	NN
cord-293938-40zyv1h8	109	5	of	of	IN
cord-293938-40zyv1h8	109	6	the	the	DT
cord-293938-40zyv1h8	109	7	hAPN	hapn	NN
cord-293938-40zyv1h8	109	8	into	into	IN
cord-293938-40zyv1h8	109	9	mouse	mouse	NN
cord-293938-40zyv1h8	109	10	cells	cell	NNS
cord-293938-40zyv1h8	109	11	is	be	VBZ
cord-293938-40zyv1h8	109	12	not	not	RB
cord-293938-40zyv1h8	109	13	enough	enough	JJ
cord-293938-40zyv1h8	109	14	to	to	TO
cord-293938-40zyv1h8	109	15	establish	establish	VB
cord-293938-40zyv1h8	109	16	robust	robust	JJ
cord-293938-40zyv1h8	109	17	HCoV-229E	HCoV-229E	NNP
cord-293938-40zyv1h8	109	18	infection	infection	NN
cord-293938-40zyv1h8	109	19	in	in	IN
cord-293938-40zyv1h8	109	20	vivo	vivo	NN
cord-293938-40zyv1h8	109	21	.	.	.
cord-293938-40zyv1h8	110	1	Nevertheless	nevertheless	RB
cord-293938-40zyv1h8	110	2	,	,	,
cord-293938-40zyv1h8	110	3	cells	cell	NNS
cord-293938-40zyv1h8	110	4	isolated	isolate	VBN
cord-293938-40zyv1h8	110	5	from	from	IN
cord-293938-40zyv1h8	110	6	these	these	DT
cord-293938-40zyv1h8	110	7	transgenic	transgenic	JJ
cord-293938-40zyv1h8	110	8	animals	animal	NNS
cord-293938-40zyv1h8	110	9	could	could	MD
cord-293938-40zyv1h8	110	10	be	be	VB
cord-293938-40zyv1h8	110	11	infected	infect	VBN
cord-293938-40zyv1h8	110	12	in	in	IN
cord-293938-40zyv1h8	110	13	vitro	vitro	FW
cord-293938-40zyv1h8	110	14	[	[	-LRB-
cord-293938-40zyv1h8	110	15	63	63	CD
cord-293938-40zyv1h8	110	16	,	,	,
cord-293938-40zyv1h8	110	17	64	64	CD
cord-293938-40zyv1h8	110	18	]	]	-RRB-
cord-293938-40zyv1h8	110	19	.	.	.
cord-293938-40zyv1h8	111	1	The	the	DT
cord-293938-40zyv1h8	111	2	emergence	emergence	NN
cord-293938-40zyv1h8	111	3	of	of	IN
cord-293938-40zyv1h8	111	4	both	both	DT
cord-293938-40zyv1h8	111	5	SARS	SARS	NNP
cord-293938-40zyv1h8	111	6	-	-	:
cord-293938-40zyv1h8	111	7	and	and	CC
cord-293938-40zyv1h8	111	8	MERS	MERS	NNP
cord-293938-40zyv1h8	111	9	-	-	HYPH
cord-293938-40zyv1h8	111	10	CoVs	CoVs	NNP
cord-293938-40zyv1h8	111	11	emphasized	emphasize	VBD
cord-293938-40zyv1h8	111	12	the	the	DT
cord-293938-40zyv1h8	111	13	importance	importance	NN
cord-293938-40zyv1h8	111	14	of	of	IN
cord-293938-40zyv1h8	111	15	establishing	establish	VBG
cord-293938-40zyv1h8	111	16	animal	animal	NN
cord-293938-40zyv1h8	111	17	models	model	NNS
cord-293938-40zyv1h8	111	18	for	for	IN
cord-293938-40zyv1h8	111	19	human	human	JJ
cord-293938-40zyv1h8	111	20	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	111	21	.	.	.
cord-293938-40zyv1h8	112	1	Currently	currently	RB
cord-293938-40zyv1h8	112	2	,	,	,
cord-293938-40zyv1h8	112	3	a	a	DT
cord-293938-40zyv1h8	112	4	few	few	JJ
cord-293938-40zyv1h8	112	5	animal	animal	NN
cord-293938-40zyv1h8	112	6	models	model	NNS
cord-293938-40zyv1h8	112	7	for	for	IN
cord-293938-40zyv1h8	112	8	MERS	MERS	NNP
cord-293938-40zyv1h8	112	9	-	-	HYPH
cord-293938-40zyv1h8	112	10	CoV	CoV	NNP
cord-293938-40zyv1h8	112	11	have	have	VBP
cord-293938-40zyv1h8	112	12	been	be	VBN
cord-293938-40zyv1h8	112	13	established	establish	VBN
cord-293938-40zyv1h8	112	14	.	.	.
cord-293938-40zyv1h8	113	1	Mice	mouse	NNS
cord-293938-40zyv1h8	113	2	carry	carry	VBP
cord-293938-40zyv1h8	113	3	their	-PRON-	PRP$
cord-293938-40zyv1h8	113	4	own	own	JJ
cord-293938-40zyv1h8	113	5	variant	variant	NN
cord-293938-40zyv1h8	113	6	of	of	IN
cord-293938-40zyv1h8	113	7	the	the	DT
cord-293938-40zyv1h8	113	8	viral	viral	JJ
cord-293938-40zyv1h8	113	9	receptor	receptor	NN
cord-293938-40zyv1h8	113	10	DDP4	DDP4	NNP
cord-293938-40zyv1h8	113	11	that	that	WDT
cord-293938-40zyv1h8	113	12	differs	differ	VBZ
cord-293938-40zyv1h8	113	13	from	from	IN
cord-293938-40zyv1h8	113	14	the	the	DT
cord-293938-40zyv1h8	113	15	human	human	NN
cord-293938-40zyv1h8	113	16	in	in	IN
cord-293938-40zyv1h8	113	17	regions	region	NNS
cord-293938-40zyv1h8	113	18	important	important	JJ
cord-293938-40zyv1h8	113	19	for	for	IN
cord-293938-40zyv1h8	113	20	MERS	MERS	NNP
cord-293938-40zyv1h8	113	21	-	-	HYPH
cord-293938-40zyv1h8	113	22	CoV	cov	NN
cord-293938-40zyv1h8	113	23	spike	spike	NN
cord-293938-40zyv1h8	113	24	interaction	interaction	NN
cord-293938-40zyv1h8	113	25	and	and	CC
cord-293938-40zyv1h8	113	26	by	by	IN
cord-293938-40zyv1h8	113	27	replacing	replace	VBG
cord-293938-40zyv1h8	113	28	this	this	DT
cord-293938-40zyv1h8	113	29	receptor	receptor	NN
cord-293938-40zyv1h8	113	30	with	with	IN
cord-293938-40zyv1h8	113	31	the	the	DT
cord-293938-40zyv1h8	113	32	human	human	JJ
cord-293938-40zyv1h8	113	33	one	one	NN
cord-293938-40zyv1h8	113	34	,	,	,
cord-293938-40zyv1h8	113	35	MERS	MERS	NNP
cord-293938-40zyv1h8	113	36	-	-	HYPH
cord-293938-40zyv1h8	113	37	CoV	CoV	NNP
cord-293938-40zyv1h8	113	38	can	can	MD
cord-293938-40zyv1h8	113	39	infect	infect	VB
cord-293938-40zyv1h8	113	40	mouse	mouse	NN
cord-293938-40zyv1h8	113	41	cells	cell	NNS
cord-293938-40zyv1h8	113	42	but	but	CC
cord-293938-40zyv1h8	113	43	the	the	DT
cord-293938-40zyv1h8	113	44	method	method	NN
cord-293938-40zyv1h8	113	45	of	of	IN
cord-293938-40zyv1h8	113	46	hDPP4	hdpp4	ADD
cord-293938-40zyv1h8	113	47	insertion	insertion	NN
cord-293938-40zyv1h8	113	48	has	have	VBZ
cord-293938-40zyv1h8	113	49	an	an	DT
cord-293938-40zyv1h8	113	50	effect	effect	NN
cord-293938-40zyv1h8	113	51	on	on	IN
cord-293938-40zyv1h8	113	52	the	the	DT
cord-293938-40zyv1h8	113	53	degree	degree	NN
cord-293938-40zyv1h8	113	54	of	of	IN
cord-293938-40zyv1h8	113	55	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	113	56	observed	observe	VBN
cord-293938-40zyv1h8	113	57	in	in	IN
cord-293938-40zyv1h8	113	58	these	these	DT
cord-293938-40zyv1h8	113	59	mice	mouse	NNS
cord-293938-40zyv1h8	113	60	[	[	-LRB-
cord-293938-40zyv1h8	113	61	65	65	CD
cord-293938-40zyv1h8	113	62	,	,	,
cord-293938-40zyv1h8	113	63	66	66	CD
cord-293938-40zyv1h8	113	64	]	]	-RRB-
cord-293938-40zyv1h8	113	65	.	.	.
cord-293938-40zyv1h8	114	1	Various	various	JJ
cord-293938-40zyv1h8	114	2	non	non	JJ
cord-293938-40zyv1h8	114	3	-	-	JJ
cord-293938-40zyv1h8	114	4	human	human	JJ
cord-293938-40zyv1h8	114	5	primates	primate	NNS
cord-293938-40zyv1h8	114	6	(	(	-LRB-
cord-293938-40zyv1h8	114	7	NHPs	NHPs	NNP
cord-293938-40zyv1h8	114	8	)	)	-RRB-
cord-293938-40zyv1h8	114	9	can	can	MD
cord-293938-40zyv1h8	114	10	be	be	VB
cord-293938-40zyv1h8	114	11	naturally	naturally	RB
cord-293938-40zyv1h8	114	12	infected	infect	VBN
cord-293938-40zyv1h8	114	13	with	with	IN
cord-293938-40zyv1h8	114	14	both	both	DT
cord-293938-40zyv1h8	114	15	SARS	SARS	NNP
cord-293938-40zyv1h8	114	16	-	-	:
cord-293938-40zyv1h8	114	17	and	and	CC
cord-293938-40zyv1h8	114	18	MERS	MERS	NNP
cord-293938-40zyv1h8	114	19	-	-	HYPH
cord-293938-40zyv1h8	114	20	CoVs	CoVs	NNP
cord-293938-40zyv1h8	114	21	.	.	.
cord-293938-40zyv1h8	115	1	However	however	RB
cord-293938-40zyv1h8	115	2	,	,	,
cord-293938-40zyv1h8	115	3	disease	disease	NN
cord-293938-40zyv1h8	115	4	presentation	presentation	NN
cord-293938-40zyv1h8	115	5	and	and	CC
cord-293938-40zyv1h8	115	6	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	115	7	differs	differ	VBZ
cord-293938-40zyv1h8	115	8	between	between	IN
cord-293938-40zyv1h8	115	9	the	the	DT
cord-293938-40zyv1h8	115	10	different	different	JJ
cord-293938-40zyv1h8	115	11	subspecies	subspecie	NNS
cord-293938-40zyv1h8	115	12	and	and	CC
cord-293938-40zyv1h8	115	13	NHP	NHP	NNP
cord-293938-40zyv1h8	115	14	models	model	NNS
cord-293938-40zyv1h8	115	15	are	be	VBP
cord-293938-40zyv1h8	115	16	expensive	expensive	JJ
cord-293938-40zyv1h8	115	17	,	,	,
cord-293938-40zyv1h8	115	18	although	although	IN
cord-293938-40zyv1h8	115	19	ideal	ideal	JJ
cord-293938-40zyv1h8	115	20	to	to	TO
cord-293938-40zyv1h8	115	21	study	study	VB
cord-293938-40zyv1h8	115	22	human	human	JJ
cord-293938-40zyv1h8	115	23	infection	infection	NN
cord-293938-40zyv1h8	115	24	due	due	IN
cord-293938-40zyv1h8	115	25	to	to	IN
cord-293938-40zyv1h8	115	26	their	-PRON-	PRP$
cord-293938-40zyv1h8	115	27	genetic	genetic	JJ
cord-293938-40zyv1h8	115	28	similarity	similarity	NN
cord-293938-40zyv1h8	115	29	[	[	-LRB-
cord-293938-40zyv1h8	115	30	62	62	CD
cord-293938-40zyv1h8	115	31	]	]	-RRB-
cord-293938-40zyv1h8	115	32	.	.	.
cord-293938-40zyv1h8	116	1	To	to	TO
cord-293938-40zyv1h8	116	2	establish	establish	VB
cord-293938-40zyv1h8	116	3	a	a	DT
cord-293938-40zyv1h8	116	4	link	link	NN
cord-293938-40zyv1h8	116	5	between	between	IN
cord-293938-40zyv1h8	116	6	the	the	DT
cord-293938-40zyv1h8	116	7	research	research	NN
cord-293938-40zyv1h8	116	8	conducted	conduct	VBN
cord-293938-40zyv1h8	116	9	in	in	IN
cord-293938-40zyv1h8	116	10	animal	animal	NN
cord-293938-40zyv1h8	116	11	models	model	NNS
cord-293938-40zyv1h8	116	12	and	and	CC
cord-293938-40zyv1h8	116	13	humans	human	NNS
cord-293938-40zyv1h8	116	14	,	,	,
cord-293938-40zyv1h8	116	15	an	an	DT
cord-293938-40zyv1h8	116	16	organotypic	organotypic	JJ
cord-293938-40zyv1h8	116	17	airway	airway	NN
cord-293938-40zyv1h8	116	18	culture	culture	NN
cord-293938-40zyv1h8	116	19	system	system	NN
cord-293938-40zyv1h8	116	20	resembling	resemble	VBG
cord-293938-40zyv1h8	116	21	the	the	DT
cord-293938-40zyv1h8	116	22	human	human	JJ
cord-293938-40zyv1h8	116	23	airway	airway	NN
cord-293938-40zyv1h8	116	24	epithelium	epithelium	NN
cord-293938-40zyv1h8	116	25	has	have	VBZ
cord-293938-40zyv1h8	116	26	been	be	VBN
cord-293938-40zyv1h8	116	27	developed	develop	VBN
cord-293938-40zyv1h8	116	28	.	.	.
cord-293938-40zyv1h8	117	1	This	this	DT
cord-293938-40zyv1h8	117	2	model	model	NN
cord-293938-40zyv1h8	117	3	is	be	VBZ
cord-293938-40zyv1h8	117	4	a	a	DT
cord-293938-40zyv1h8	117	5	universal	universal	JJ
cord-293938-40zyv1h8	117	6	platform	platform	NN
cord-293938-40zyv1h8	117	7	to	to	TO
cord-293938-40zyv1h8	117	8	study	study	VB
cord-293938-40zyv1h8	117	9	human	human	JJ
cord-293938-40zyv1h8	117	10	respiratory	respiratory	JJ
cord-293938-40zyv1h8	117	11	viruses	virus	NNS
cord-293938-40zyv1h8	117	12	[	[	-LRB-
cord-293938-40zyv1h8	117	13	67	67	CD
cord-293938-40zyv1h8	117	14	]	]	-RRB-
cord-293938-40zyv1h8	117	15	[	[	-LRB-
cord-293938-40zyv1h8	117	16	68	68	CD
cord-293938-40zyv1h8	117	17	]	]	-RRB-
cord-293938-40zyv1h8	117	18	[	[	-LRB-
cord-293938-40zyv1h8	117	19	69	69	CD
cord-293938-40zyv1h8	117	20	]	]	-RRB-
cord-293938-40zyv1h8	117	21	[	[	-LRB-
cord-293938-40zyv1h8	117	22	70	70	CD
cord-293938-40zyv1h8	117	23	]	]	-RRB-
cord-293938-40zyv1h8	117	24	.	.	.
cord-293938-40zyv1h8	118	1	They	-PRON-	PRP
cord-293938-40zyv1h8	118	2	have	have	VBP
cord-293938-40zyv1h8	118	3	been	be	VBN
cord-293938-40zyv1h8	118	4	used	use	VBN
cord-293938-40zyv1h8	118	5	successfully	successfully	RB
cord-293938-40zyv1h8	118	6	for	for	IN
cord-293938-40zyv1h8	118	7	infection	infection	NN
cord-293938-40zyv1h8	118	8	studies	study	NNS
cord-293938-40zyv1h8	118	9	with	with	IN
cord-293938-40zyv1h8	118	10	all	all	DT
cord-293938-40zyv1h8	118	11	known	know	VBN
cord-293938-40zyv1h8	118	12	human	human	JJ
cord-293938-40zyv1h8	118	13	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	118	14	[	[	-LRB-
cord-293938-40zyv1h8	118	15	56	56	CD
cord-293938-40zyv1h8	118	16	,	,	,
cord-293938-40zyv1h8	118	17	57	57	CD
cord-293938-40zyv1h8	118	18	]	]	-RRB-
cord-293938-40zyv1h8	118	19	.	.	.
cord-293938-40zyv1h8	119	1	Furthermore	furthermore	RB
cord-293938-40zyv1h8	119	2	,	,	,
cord-293938-40zyv1h8	119	3	the	the	DT
cord-293938-40zyv1h8	119	4	cultures	culture	NNS
cord-293938-40zyv1h8	119	5	can	can	MD
cord-293938-40zyv1h8	119	6	be	be	VB
cord-293938-40zyv1h8	119	7	inoculated	inoculate	VBN
cord-293938-40zyv1h8	119	8	with	with	IN
cord-293938-40zyv1h8	119	9	a	a	DT
cord-293938-40zyv1h8	119	10	low	low	JJ
cord-293938-40zyv1h8	119	11	infectious	infectious	JJ
cord-293938-40zyv1h8	119	12	dosage	dosage	NN
cord-293938-40zyv1h8	119	13	to	to	TO
cord-293938-40zyv1h8	119	14	mimic	mimic	VB
cord-293938-40zyv1h8	119	15	natural	natural	JJ
cord-293938-40zyv1h8	119	16	infection	infection	NN
cord-293938-40zyv1h8	119	17	in	in	IN
cord-293938-40zyv1h8	119	18	the	the	DT
cord-293938-40zyv1h8	119	19	human	human	JJ
cord-293938-40zyv1h8	119	20	airway	airway	NN
cord-293938-40zyv1h8	119	21	.	.	.
cord-293938-40zyv1h8	120	1	Whereas	whereas	IN
cord-293938-40zyv1h8	120	2	,	,	,
cord-293938-40zyv1h8	120	3	animal	animal	NN
cord-293938-40zyv1h8	120	4	models	model	NNS
cord-293938-40zyv1h8	120	5	often	often	RB
cord-293938-40zyv1h8	120	6	require	require	VBP
cord-293938-40zyv1h8	120	7	both	both	DT
cord-293938-40zyv1h8	120	8	high	high	JJ
cord-293938-40zyv1h8	120	9	dosage	dosage	NN
cord-293938-40zyv1h8	120	10	and	and	CC
cord-293938-40zyv1h8	120	11	artificial	artificial	JJ
cord-293938-40zyv1h8	120	12	inoculation	inoculation	NN
cord-293938-40zyv1h8	120	13	routes	route	NNS
cord-293938-40zyv1h8	120	14	.	.	.
cord-293938-40zyv1h8	121	1	Organotypic	Organotypic	NNP
cord-293938-40zyv1h8	121	2	cell	cell	NN
cord-293938-40zyv1h8	121	3	cultures	culture	NNS
cord-293938-40zyv1h8	121	4	are	be	VBP
cord-293938-40zyv1h8	121	5	becoming	become	VBG
cord-293938-40zyv1h8	121	6	increasingly	increasingly	RB
cord-293938-40zyv1h8	121	7	common	common	JJ
cord-293938-40zyv1h8	121	8	.	.	.
cord-293938-40zyv1h8	122	1	Different	different	JJ
cord-293938-40zyv1h8	122	2	cell	cell	NN
cord-293938-40zyv1h8	122	3	culture	culture	NN
cord-293938-40zyv1h8	122	4	models	model	NNS
cord-293938-40zyv1h8	122	5	exist	exist	VBP
cord-293938-40zyv1h8	122	6	to	to	TO
cord-293938-40zyv1h8	122	7	depict	depict	VB
cord-293938-40zyv1h8	122	8	different	different	JJ
cord-293938-40zyv1h8	122	9	epithelial	epithelial	JJ
cord-293938-40zyv1h8	122	10	tissues	tissue	NNS
cord-293938-40zyv1h8	122	11	[	[	-LRB-
cord-293938-40zyv1h8	122	12	71	71	CD
cord-293938-40zyv1h8	122	13	]	]	-RRB-
cord-293938-40zyv1h8	122	14	.	.	.
cord-293938-40zyv1h8	123	1	These	these	DT
cord-293938-40zyv1h8	123	2	cultures	culture	NNS
cord-293938-40zyv1h8	123	3	closely	closely	RB
cord-293938-40zyv1h8	123	4	resemble	resemble	VBP
cord-293938-40zyv1h8	123	5	their	-PRON-	PRP$
cord-293938-40zyv1h8	123	6	tissue	tissue	NN
cord-293938-40zyv1h8	123	7	of	of	IN
cord-293938-40zyv1h8	123	8	origin	origin	NN
cord-293938-40zyv1h8	123	9	and	and	CC
cord-293938-40zyv1h8	123	10	contain	contain	VBP
cord-293938-40zyv1h8	123	11	various	various	JJ
cord-293938-40zyv1h8	123	12	different	different	JJ
cord-293938-40zyv1h8	123	13	cell	cell	NN
cord-293938-40zyv1h8	123	14	types	type	NNS
cord-293938-40zyv1h8	123	15	with	with	IN
cord-293938-40zyv1h8	123	16	distinctive	distinctive	JJ
cord-293938-40zyv1h8	123	17	roles	role	NNS
cord-293938-40zyv1h8	123	18	in	in	IN
cord-293938-40zyv1h8	123	19	the	the	DT
cord-293938-40zyv1h8	123	20	polarized	polarized	JJ
cord-293938-40zyv1h8	123	21	tissue	tissue	NN
cord-293938-40zyv1h8	123	22	.	.	.
cord-293938-40zyv1h8	124	1	Currently	currently	RB
cord-293938-40zyv1h8	124	2	,	,	,
cord-293938-40zyv1h8	124	3	various	various	JJ
cord-293938-40zyv1h8	124	4	organotypic	organotypic	JJ
cord-293938-40zyv1h8	124	5	cell	cell	NN
cord-293938-40zyv1h8	124	6	culture	culture	NN
cord-293938-40zyv1h8	124	7	models	model	NNS
cord-293938-40zyv1h8	124	8	exist	exist	VBP
cord-293938-40zyv1h8	124	9	to	to	TO
cord-293938-40zyv1h8	124	10	represent	represent	VB
cord-293938-40zyv1h8	124	11	the	the	DT
cord-293938-40zyv1h8	124	12	different	different	JJ
cord-293938-40zyv1h8	124	13	areas	area	NNS
cord-293938-40zyv1h8	124	14	of	of	IN
cord-293938-40zyv1h8	124	15	the	the	DT
cord-293938-40zyv1h8	124	16	human	human	NNP
cord-293938-40zyv1h8	124	17	airways	airways	NNP
cord-293938-40zyv1h8	124	18	.	.	.
cord-293938-40zyv1h8	125	1	The	the	DT
cord-293938-40zyv1h8	125	2	human	human	JJ
cord-293938-40zyv1h8	125	3	lungs	lung	NNS
cord-293938-40zyv1h8	125	4	span	span	VBP
cord-293938-40zyv1h8	125	5	a	a	DT
cord-293938-40zyv1h8	125	6	long	long	JJ
cord-293938-40zyv1h8	125	7	anatomical	anatomical	JJ
cord-293938-40zyv1h8	125	8	distance	distance	NN
cord-293938-40zyv1h8	125	9	and	and	CC
cord-293938-40zyv1h8	125	10	carry	carry	VB
cord-293938-40zyv1h8	125	11	out	out	RP
cord-293938-40zyv1h8	125	12	different	different	JJ
cord-293938-40zyv1h8	125	13	functions	function	NNS
cord-293938-40zyv1h8	125	14	depending	depend	VBG
cord-293938-40zyv1h8	125	15	on	on	IN
cord-293938-40zyv1h8	125	16	anatomical	anatomical	JJ
cord-293938-40zyv1h8	125	17	location	location	NN
cord-293938-40zyv1h8	125	18	[	[	-LRB-
cord-293938-40zyv1h8	125	19	72	72	CD
cord-293938-40zyv1h8	125	20	,	,	,
cord-293938-40zyv1h8	125	21	73	73	CD
cord-293938-40zyv1h8	125	22	]	]	-RRB-
cord-293938-40zyv1h8	125	23	.	.	.
cord-293938-40zyv1h8	126	1	The	the	DT
cord-293938-40zyv1h8	126	2	structure	structure	NN
cord-293938-40zyv1h8	126	3	of	of	IN
cord-293938-40zyv1h8	126	4	the	the	DT
cord-293938-40zyv1h8	126	5	epithelium	epithelium	NN
cord-293938-40zyv1h8	126	6	also	also	RB
cord-293938-40zyv1h8	126	7	differs	differ	VBZ
cord-293938-40zyv1h8	126	8	the	the	DT
cord-293938-40zyv1h8	126	9	further	further	JJ
cord-293938-40zyv1h8	126	10	you	-PRON-	PRP
cord-293938-40zyv1h8	126	11	descend	descend	VBP
cord-293938-40zyv1h8	126	12	into	into	IN
cord-293938-40zyv1h8	126	13	the	the	DT
cord-293938-40zyv1h8	126	14	airways	airway	NNS
cord-293938-40zyv1h8	126	15	.	.	.
cord-293938-40zyv1h8	127	1	Tracheal	Tracheal	NNP
cord-293938-40zyv1h8	127	2	and	and	CC
cord-293938-40zyv1h8	127	3	bronchial	bronchial	JJ
cord-293938-40zyv1h8	127	4	epithelium	epithelium	NN
cord-293938-40zyv1h8	127	5	is	be	VBZ
cord-293938-40zyv1h8	127	6	columnar	columnar	JJ
cord-293938-40zyv1h8	127	7	and	and	CC
cord-293938-40zyv1h8	127	8	pseudostratified	pseudostratified	JJ
cord-293938-40zyv1h8	127	9	,	,	,
cord-293938-40zyv1h8	127	10	with	with	IN
cord-293938-40zyv1h8	127	11	every	every	DT
cord-293938-40zyv1h8	127	12	cell	cell	NN
cord-293938-40zyv1h8	127	13	in	in	IN
cord-293938-40zyv1h8	127	14	contact	contact	NN
cord-293938-40zyv1h8	127	15	with	with	IN
cord-293938-40zyv1h8	127	16	the	the	DT
cord-293938-40zyv1h8	127	17	basement	basement	NN
cord-293938-40zyv1h8	127	18	membrane	membrane	NN
cord-293938-40zyv1h8	127	19	,	,	,
cord-293938-40zyv1h8	127	20	while	while	IN
cord-293938-40zyv1h8	127	21	the	the	DT
cord-293938-40zyv1h8	127	22	epithelium	epithelium	NN
cord-293938-40zyv1h8	127	23	in	in	IN
cord-293938-40zyv1h8	127	24	the	the	DT
cord-293938-40zyv1h8	127	25	alveoli	alveolus	NNS
cord-293938-40zyv1h8	127	26	is	be	VBZ
cord-293938-40zyv1h8	127	27	comprised	comprise	VBN
cord-293938-40zyv1h8	127	28	of	of	IN
cord-293938-40zyv1h8	127	29	a	a	DT
cord-293938-40zyv1h8	127	30	single	single	JJ
cord-293938-40zyv1h8	127	31	cell	cell	NN
cord-293938-40zyv1h8	127	32	layer	layer	NN
cord-293938-40zyv1h8	127	33	to	to	TO
cord-293938-40zyv1h8	127	34	facilitate	facilitate	VB
cord-293938-40zyv1h8	127	35	air	air	NN
cord-293938-40zyv1h8	127	36	-	-	HYPH
cord-293938-40zyv1h8	127	37	exchange	exchange	NN
cord-293938-40zyv1h8	127	38	[	[	-LRB-
cord-293938-40zyv1h8	127	39	74	74	CD
cord-293938-40zyv1h8	127	40	]	]	-RRB-
cord-293938-40zyv1h8	127	41	.	.	.
cord-293938-40zyv1h8	128	1	Tracheobronchial	tracheobronchial	JJ
cord-293938-40zyv1h8	128	2	cells	cell	NNS
cord-293938-40zyv1h8	128	3	are	be	VBP
cord-293938-40zyv1h8	128	4	one	one	CD
cord-293938-40zyv1h8	128	5	of	of	IN
cord-293938-40zyv1h8	128	6	the	the	DT
cord-293938-40zyv1h8	128	7	first	first	JJ
cord-293938-40zyv1h8	128	8	targets	target	NNS
cord-293938-40zyv1h8	128	9	of	of	IN
cord-293938-40zyv1h8	128	10	human	human	JJ
cord-293938-40zyv1h8	128	11	respiratory	respiratory	JJ
cord-293938-40zyv1h8	128	12	viruses	virus	NNS
cord-293938-40zyv1h8	128	13	and	and	CC
cord-293938-40zyv1h8	128	14	can	can	MD
cord-293938-40zyv1h8	128	15	be	be	VB
cord-293938-40zyv1h8	128	16	cultured	culture	VBN
cord-293938-40zyv1h8	128	17	in	in	IN
cord-293938-40zyv1h8	128	18	airliquid	airliquid	JJ
cord-293938-40zyv1h8	128	19	interface	interface	NN
cord-293938-40zyv1h8	128	20	(	(	-LRB-
cord-293938-40zyv1h8	128	21	ALI	ALI	NNP
cord-293938-40zyv1h8	128	22	)	)	-RRB-
cord-293938-40zyv1h8	128	23	where	where	WRB
cord-293938-40zyv1h8	128	24	the	the	DT
cord-293938-40zyv1h8	128	25	apical	apical	JJ
cord-293938-40zyv1h8	128	26	side	side	NN
cord-293938-40zyv1h8	128	27	of	of	IN
cord-293938-40zyv1h8	128	28	the	the	DT
cord-293938-40zyv1h8	128	29	cell	cell	NN
cord-293938-40zyv1h8	128	30	layer	layer	NN
cord-293938-40zyv1h8	128	31	is	be	VBZ
cord-293938-40zyv1h8	128	32	exposed	expose	VBN
cord-293938-40zyv1h8	128	33	to	to	IN
cord-293938-40zyv1h8	128	34	air	air	NN
cord-293938-40zyv1h8	128	35	while	while	IN
cord-293938-40zyv1h8	128	36	the	the	DT
cord-293938-40zyv1h8	128	37	basolateral	basolateral	JJ
cord-293938-40zyv1h8	128	38	side	side	NN
cord-293938-40zyv1h8	128	39	is	be	VBZ
cord-293938-40zyv1h8	128	40	submerged	submerge	VBN
cord-293938-40zyv1h8	128	41	in	in	IN
cord-293938-40zyv1h8	128	42	medium	medium	NN
cord-293938-40zyv1h8	128	43	.	.	.
cord-293938-40zyv1h8	129	1	Tracheobronchial	tracheobronchial	JJ
cord-293938-40zyv1h8	129	2	cells	cell	NNS
cord-293938-40zyv1h8	129	3	cultured	culture	VBN
cord-293938-40zyv1h8	129	4	in	in	IN
cord-293938-40zyv1h8	129	5	that	that	DT
cord-293938-40zyv1h8	129	6	way	way	NN
cord-293938-40zyv1h8	129	7	form	form	VB
cord-293938-40zyv1h8	129	8	a	a	DT
cord-293938-40zyv1h8	129	9	pseudostratified	pseudostratified	JJ
cord-293938-40zyv1h8	129	10	epithelial	epithelial	JJ
cord-293938-40zyv1h8	129	11	layer	layer	NN
cord-293938-40zyv1h8	129	12	that	that	WDT
cord-293938-40zyv1h8	129	13	both	both	CC
cord-293938-40zyv1h8	129	14	morphologically	morphologically	RB
cord-293938-40zyv1h8	129	15	and	and	CC
cord-293938-40zyv1h8	129	16	functionally	functionally	RB
cord-293938-40zyv1h8	129	17	resembles	resemble	VBZ
cord-293938-40zyv1h8	129	18	the	the	DT
cord-293938-40zyv1h8	129	19	human	human	JJ
cord-293938-40zyv1h8	129	20	upper	upper	JJ
cord-293938-40zyv1h8	129	21	conducting	conduct	VBG
cord-293938-40zyv1h8	129	22	airway	airway	NN
cord-293938-40zyv1h8	129	23	(	(	-LRB-
cord-293938-40zyv1h8	129	24	Fig	Fig	NNP
cord-293938-40zyv1h8	129	25	.	.	.
cord-293938-40zyv1h8	129	26	1a	1a	CD
cord-293938-40zyv1h8	129	27	)	)	-RRB-
cord-293938-40zyv1h8	129	28	[	[	-LRB-
cord-293938-40zyv1h8	129	29	75	75	CD
cord-293938-40zyv1h8	129	30	,	,	,
cord-293938-40zyv1h8	129	31	76	76	CD
cord-293938-40zyv1h8	129	32	]	]	-RRB-
cord-293938-40zyv1h8	129	33	.	.	.
cord-293938-40zyv1h8	130	1	After	after	IN
cord-293938-40zyv1h8	130	2	differentiation	differentiation	NN
cord-293938-40zyv1h8	130	3	,	,	,
cord-293938-40zyv1h8	130	4	these	these	DT
cord-293938-40zyv1h8	130	5	cultures	culture	NNS
cord-293938-40zyv1h8	130	6	contain	contain	VBP
cord-293938-40zyv1h8	130	7	many	many	JJ
cord-293938-40zyv1h8	130	8	different	different	JJ
cord-293938-40zyv1h8	130	9	cell	cell	NN
cord-293938-40zyv1h8	130	10	types	type	NNS
cord-293938-40zyv1h8	130	11	such	such	JJ
cord-293938-40zyv1h8	130	12	as	as	IN
cord-293938-40zyv1h8	130	13	basal	basal	NN
cord-293938-40zyv1h8	130	14	,	,	,
cord-293938-40zyv1h8	130	15	ciliated	ciliated	JJ
cord-293938-40zyv1h8	130	16	and	and	CC
cord-293938-40zyv1h8	130	17	goblet	goblet	NN
cord-293938-40zyv1h8	130	18	cells	cell	NNS
cord-293938-40zyv1h8	130	19	.	.	.
cord-293938-40zyv1h8	131	1	They	-PRON-	PRP
cord-293938-40zyv1h8	131	2	also	also	RB
cord-293938-40zyv1h8	131	3	produce	produce	VBP
cord-293938-40zyv1h8	131	4	protective	protective	JJ
cord-293938-40zyv1h8	131	5	mucus	mucus	NN
cord-293938-40zyv1h8	131	6	,	,	,
cord-293938-40zyv1h8	131	7	much	much	RB
cord-293938-40zyv1h8	131	8	like	like	IN
cord-293938-40zyv1h8	131	9	in	in	IN
cord-293938-40zyv1h8	131	10	vivo	vivo	NN
cord-293938-40zyv1h8	131	11	epithelium	epithelium	NN
cord-293938-40zyv1h8	131	12	.	.	.
cord-293938-40zyv1h8	132	1	When	when	WRB
cord-293938-40zyv1h8	132	2	compared	compare	VBN
cord-293938-40zyv1h8	132	3	to	to	IN
cord-293938-40zyv1h8	132	4	primary	primary	JJ
cord-293938-40zyv1h8	132	5	bronchial	bronchial	JJ
cord-293938-40zyv1h8	132	6	cells	cell	NNS
cord-293938-40zyv1h8	132	7	in	in	IN
cord-293938-40zyv1h8	132	8	submerged	submerge	VBN
cord-293938-40zyv1h8	132	9	two	two	CD
cord-293938-40zyv1h8	132	10	-	-	HYPH
cord-293938-40zyv1h8	132	11	dimensional	dimensional	JJ
cord-293938-40zyv1h8	132	12	culture	culture	NN
cord-293938-40zyv1h8	132	13	,	,	,
cord-293938-40zyv1h8	132	14	the	the	DT
cord-293938-40zyv1h8	132	15	gene	gene	NN
cord-293938-40zyv1h8	132	16	expression	expression	NN
cord-293938-40zyv1h8	132	17	of	of	IN
cord-293938-40zyv1h8	132	18	primary	primary	JJ
cord-293938-40zyv1h8	132	19	ALI	ALI	NNP
cord-293938-40zyv1h8	132	20	cultures	culture	NNS
cord-293938-40zyv1h8	132	21	differs	differ	VBZ
cord-293938-40zyv1h8	132	22	significantly	significantly	RB
cord-293938-40zyv1h8	132	23	.	.	.
cord-293938-40zyv1h8	133	1	However	however	RB
cord-293938-40zyv1h8	133	2	,	,	,
cord-293938-40zyv1h8	133	3	the	the	DT
cord-293938-40zyv1h8	133	4	expression	expression	NN
cord-293938-40zyv1h8	133	5	pattern	pattern	NN
cord-293938-40zyv1h8	133	6	of	of	IN
cord-293938-40zyv1h8	133	7	primary	primary	JJ
cord-293938-40zyv1h8	133	8	human	human	JJ
cord-293938-40zyv1h8	133	9	bronchial	bronchial	NN
cord-293938-40zyv1h8	133	10	ALI	ALI	NNP
cord-293938-40zyv1h8	133	11	cultures	culture	NNS
cord-293938-40zyv1h8	133	12	is	be	VBZ
cord-293938-40zyv1h8	133	13	comparable	comparable	JJ
cord-293938-40zyv1h8	133	14	to	to	IN
cord-293938-40zyv1h8	133	15	that	that	DT
cord-293938-40zyv1h8	133	16	of	of	IN
cord-293938-40zyv1h8	133	17	in	in	IN
cord-293938-40zyv1h8	133	18	vivo	vivo	NN
cord-293938-40zyv1h8	133	19	epithelium	epithelium	NN
cord-293938-40zyv1h8	133	20	.	.	.
cord-293938-40zyv1h8	134	1	The	the	DT
cord-293938-40zyv1h8	134	2	human	human	JJ
cord-293938-40zyv1h8	134	3	bronchial	bronchial	JJ
cord-293938-40zyv1h8	134	4	cell	cell	NN
cord-293938-40zyv1h8	134	5	line	line	NN
cord-293938-40zyv1h8	134	6	Calu-3	Calu-3	NNP
cord-293938-40zyv1h8	134	7	has	have	VBZ
cord-293938-40zyv1h8	134	8	been	be	VBN
cord-293938-40zyv1h8	134	9	used	use	VBN
cord-293938-40zyv1h8	134	10	as	as	IN
cord-293938-40zyv1h8	134	11	a	a	DT
cord-293938-40zyv1h8	134	12	culture	culture	NN
cord-293938-40zyv1h8	134	13	model	model	NN
cord-293938-40zyv1h8	134	14	for	for	IN
cord-293938-40zyv1h8	134	15	respiratory	respiratory	JJ
cord-293938-40zyv1h8	134	16	epithelium	epithelium	NN
cord-293938-40zyv1h8	134	17	but	but	CC
cord-293938-40zyv1h8	134	18	its	-PRON-	PRP$
cord-293938-40zyv1h8	134	19	gene	gene	NN
cord-293938-40zyv1h8	134	20	expression	expression	NN
cord-293938-40zyv1h8	134	21	in	in	IN
cord-293938-40zyv1h8	134	22	ALI	ALI	NNP
cord-293938-40zyv1h8	134	23	cultures	culture	NNS
cord-293938-40zyv1h8	134	24	is	be	VBZ
cord-293938-40zyv1h8	134	25	more	more	RBR
cord-293938-40zyv1h8	134	26	similar	similar	JJ
cord-293938-40zyv1h8	134	27	to	to	IN
cord-293938-40zyv1h8	134	28	submerged	submerged	JJ
cord-293938-40zyv1h8	134	29	bronchial	bronchial	JJ
cord-293938-40zyv1h8	134	30	cell	cell	NN
cord-293938-40zyv1h8	134	31	cultures	culture	NNS
cord-293938-40zyv1h8	134	32	than	than	IN
cord-293938-40zyv1h8	134	33	differentiated	differentiated	JJ
cord-293938-40zyv1h8	134	34	epithelium	epithelium	NN
cord-293938-40zyv1h8	134	35	[	[	-LRB-
cord-293938-40zyv1h8	134	36	77	77	CD
cord-293938-40zyv1h8	134	37	]	]	-RRB-
cord-293938-40zyv1h8	134	38	.	.	.
cord-293938-40zyv1h8	135	1	disruption	disruption	NN
cord-293938-40zyv1h8	135	2	of	of	IN
cord-293938-40zyv1h8	135	3	the	the	DT
cord-293938-40zyv1h8	135	4	cell	cell	NN
cord-293938-40zyv1h8	135	5	layer	layer	NN
cord-293938-40zyv1h8	135	6	[	[	-LRB-
cord-293938-40zyv1h8	135	7	57	57	CD
cord-293938-40zyv1h8	135	8	]	]	-RRB-
cord-293938-40zyv1h8	135	9	.	.	.
cord-293938-40zyv1h8	136	1	Therefore	therefore	RB
cord-293938-40zyv1h8	136	2	,	,	,
cord-293938-40zyv1h8	136	3	the	the	DT
cord-293938-40zyv1h8	136	4	primary	primary	JJ
cord-293938-40zyv1h8	136	5	tracheobronchial	tracheobronchial	NN
cord-293938-40zyv1h8	136	6	ALI	ALI	NNP
cord-293938-40zyv1h8	136	7	culture	culture	NN
cord-293938-40zyv1h8	136	8	model	model	NN
cord-293938-40zyv1h8	136	9	is	be	VBZ
cord-293938-40zyv1h8	136	10	especially	especially	RB
cord-293938-40zyv1h8	136	11	fitting	fitting	JJ
cord-293938-40zyv1h8	136	12	for	for	IN
cord-293938-40zyv1h8	136	13	human	human	JJ
cord-293938-40zyv1h8	136	14	respiratory	respiratory	JJ
cord-293938-40zyv1h8	136	15	virus	virus	NN
cord-293938-40zyv1h8	136	16	research	research	NN
cord-293938-40zyv1h8	136	17	since	since	IN
cord-293938-40zyv1h8	136	18	it	-PRON-	PRP
cord-293938-40zyv1h8	136	19	accurately	accurately	RB
cord-293938-40zyv1h8	136	20	recapitulates	recapitulate	VBZ
cord-293938-40zyv1h8	136	21	the	the	DT
cord-293938-40zyv1h8	136	22	primary	primary	JJ
cord-293938-40zyv1h8	136	23	entry	entry	NN
cord-293938-40zyv1h8	136	24	point	point	NN
cord-293938-40zyv1h8	136	25	for	for	IN
cord-293938-40zyv1h8	136	26	these	these	DT
cord-293938-40zyv1h8	136	27	viruses	virus	NNS
cord-293938-40zyv1h8	136	28	.	.	.
cord-293938-40zyv1h8	137	1	By	by	IN
cord-293938-40zyv1h8	137	2	using	use	VBG
cord-293938-40zyv1h8	137	3	these	these	DT
cord-293938-40zyv1h8	137	4	cultures	culture	NNS
cord-293938-40zyv1h8	137	5	,	,	,
cord-293938-40zyv1h8	137	6	virus	virus	NN
cord-293938-40zyv1h8	137	7	replication	replication	NN
cord-293938-40zyv1h8	137	8	and	and	CC
cord-293938-40zyv1h8	137	9	host	host	NN
cord-293938-40zyv1h8	137	10	interactions	interaction	NNS
cord-293938-40zyv1h8	137	11	can	can	MD
cord-293938-40zyv1h8	137	12	be	be	VB
cord-293938-40zyv1h8	137	13	studied	study	VBN
cord-293938-40zyv1h8	137	14	in	in	IN
cord-293938-40zyv1h8	137	15	natural	natural	JJ
cord-293938-40zyv1h8	137	16	target	target	NN
cord-293938-40zyv1h8	137	17	cells	cell	NNS
cord-293938-40zyv1h8	137	18	.	.	.
cord-293938-40zyv1h8	138	1	Further	further	RB
cord-293938-40zyv1h8	138	2	establishing	establish	VBG
cord-293938-40zyv1h8	138	3	the	the	DT
cord-293938-40zyv1h8	138	4	usefulness	usefulness	NN
cord-293938-40zyv1h8	138	5	of	of	IN
cord-293938-40zyv1h8	138	6	this	this	DT
cord-293938-40zyv1h8	138	7	system	system	NN
cord-293938-40zyv1h8	138	8	HCoV	HCoV	NNP
cord-293938-40zyv1h8	138	9	-	-	HYPH
cord-293938-40zyv1h8	138	10	HKU1	HKU1	NNP
cord-293938-40zyv1h8	138	11	was	be	VBD
cord-293938-40zyv1h8	138	12	propagated	propagate	VBN
cord-293938-40zyv1h8	138	13	for	for	IN
cord-293938-40zyv1h8	138	14	the	the	DT
cord-293938-40zyv1h8	138	15	first	first	JJ
cord-293938-40zyv1h8	138	16	time	time	NN
cord-293938-40zyv1h8	138	17	in	in	IN
cord-293938-40zyv1h8	138	18	ciliated	ciliated	JJ
cord-293938-40zyv1h8	138	19	cells	cell	NNS
cord-293938-40zyv1h8	138	20	of	of	IN
cord-293938-40zyv1h8	138	21	bronchial	bronchial	JJ
cord-293938-40zyv1h8	138	22	HAE	HAE	NNP
cord-293938-40zyv1h8	138	23	cultures	culture	NNS
cord-293938-40zyv1h8	138	24	in	in	IN
cord-293938-40zyv1h8	138	25	2010	2010	CD
cord-293938-40zyv1h8	138	26	after	after	IN
cord-293938-40zyv1h8	138	27	culturing	culture	VBG
cord-293938-40zyv1h8	138	28	it	-PRON-	PRP
cord-293938-40zyv1h8	138	29	in	in	IN
cord-293938-40zyv1h8	138	30	conventional	conventional	JJ
cord-293938-40zyv1h8	138	31	cell	cell	NN
cord-293938-40zyv1h8	138	32	lines	line	NNS
cord-293938-40zyv1h8	138	33	had	have	VBD
cord-293938-40zyv1h8	138	34	failed	fail	VBN
cord-293938-40zyv1h8	138	35	[	[	-LRB-
cord-293938-40zyv1h8	138	36	26	26	CD
cord-293938-40zyv1h8	138	37	]	]	-RRB-
cord-293938-40zyv1h8	138	38	.	.	.
cord-293938-40zyv1h8	139	1	Alveolar	alveolar	JJ
cord-293938-40zyv1h8	139	2	epithelial	epithelial	JJ
cord-293938-40zyv1h8	139	3	ALI	ALI	NNP
cord-293938-40zyv1h8	139	4	cultures	culture	NNS
cord-293938-40zyv1h8	139	5	(	(	-LRB-
cord-293938-40zyv1h8	139	6	Fig	fig	NN
cord-293938-40zyv1h8	139	7	.	.	.
cord-293938-40zyv1h8	139	8	1b	1b	CD
cord-293938-40zyv1h8	139	9	)	)	-RRB-
cord-293938-40zyv1h8	139	10	can	can	MD
cord-293938-40zyv1h8	139	11	also	also	RB
cord-293938-40zyv1h8	139	12	be	be	VB
cord-293938-40zyv1h8	139	13	used	use	VBN
cord-293938-40zyv1h8	139	14	for	for	IN
cord-293938-40zyv1h8	139	15	virus	virus	NN
cord-293938-40zyv1h8	139	16	-	-	HYPH
cord-293938-40zyv1h8	139	17	host	host	NN
cord-293938-40zyv1h8	139	18	interaction	interaction	NN
cord-293938-40zyv1h8	139	19	studies	study	NNS
cord-293938-40zyv1h8	139	20	and	and	CC
cord-293938-40zyv1h8	139	21	are	be	VBP
cord-293938-40zyv1h8	139	22	especially	especially	RB
cord-293938-40zyv1h8	139	23	applicable	applicable	JJ
cord-293938-40zyv1h8	139	24	when	when	WRB
cord-293938-40zyv1h8	139	25	a	a	DT
cord-293938-40zyv1h8	139	26	viral	viral	JJ
cord-293938-40zyv1h8	139	27	infection	infection	NN
cord-293938-40zyv1h8	139	28	causes	cause	VBZ
cord-293938-40zyv1h8	139	29	pneumonia	pneumonia	NN
cord-293938-40zyv1h8	139	30	and	and	CC
cord-293938-40zyv1h8	139	31	alveolar	alveolar	NN
cord-293938-40zyv1h8	139	32	damage	damage	NN
cord-293938-40zyv1h8	139	33	[	[	-LRB-
cord-293938-40zyv1h8	139	34	79	79	CD
cord-293938-40zyv1h8	139	35	]	]	-RRB-
cord-293938-40zyv1h8	139	36	.	.	.
cord-293938-40zyv1h8	140	1	HCoV	HCoV	NNP
cord-293938-40zyv1h8	140	2	-	-	HYPH
cord-293938-40zyv1h8	140	3	HKU1	HKU1	NNP
cord-293938-40zyv1h8	140	4	has	have	VBZ
cord-293938-40zyv1h8	140	5	also	also	RB
cord-293938-40zyv1h8	140	6	been	be	VBN
cord-293938-40zyv1h8	140	7	propagated	propagate	VBN
cord-293938-40zyv1h8	140	8	in	in	IN
cord-293938-40zyv1h8	140	9	alveolar	alveolar	NN
cord-293938-40zyv1h8	140	10	HAE	HAE	NNP
cord-293938-40zyv1h8	140	11	cultures	culture	NNS
cord-293938-40zyv1h8	140	12	and	and	CC
cord-293938-40zyv1h8	140	13	exhibits	exhibit	VBZ
cord-293938-40zyv1h8	140	14	a	a	DT
cord-293938-40zyv1h8	140	15	strong	strong	JJ
cord-293938-40zyv1h8	140	16	tropism	tropism	NN
cord-293938-40zyv1h8	140	17	for	for	IN
cord-293938-40zyv1h8	140	18	alveolar	alveolar	JJ
cord-293938-40zyv1h8	140	19	type	type	NN
cord-293938-40zyv1h8	140	20	II	ii	CD
cord-293938-40zyv1h8	140	21	cells	cell	NNS
cord-293938-40zyv1h8	140	22	and	and	CC
cord-293938-40zyv1h8	140	23	causes	cause	VBZ
cord-293938-40zyv1h8	140	24	large	large	JJ
cord-293938-40zyv1h8	140	25	syncytia	syncytia	NN
cord-293938-40zyv1h8	140	26	formation	formation	NN
cord-293938-40zyv1h8	140	27	upon	upon	IN
cord-293938-40zyv1h8	140	28	infection	infection	NN
cord-293938-40zyv1h8	140	29	[	[	-LRB-
cord-293938-40zyv1h8	140	30	80	80	CD
cord-293938-40zyv1h8	140	31	]	]	-RRB-
cord-293938-40zyv1h8	140	32	.	.	.
cord-293938-40zyv1h8	141	1	When	when	WRB
cord-293938-40zyv1h8	141	2	compared	compare	VBN
cord-293938-40zyv1h8	141	3	to	to	IN
cord-293938-40zyv1h8	141	4	traditional	traditional	JJ
cord-293938-40zyv1h8	141	5	two	two	CD
cord-293938-40zyv1h8	141	6	dimensional	dimensional	JJ
cord-293938-40zyv1h8	141	7	cell	cell	NN
cord-293938-40zyv1h8	141	8	cultures	culture	NNS
cord-293938-40zyv1h8	141	9	,	,	,
cord-293938-40zyv1h8	141	10	the	the	DT
cord-293938-40zyv1h8	141	11	HAE	HAE	NNP
cord-293938-40zyv1h8	141	12	cultures	culture	NNS
cord-293938-40zyv1h8	141	13	are	be	VBP
cord-293938-40zyv1h8	141	14	more	more	RBR
cord-293938-40zyv1h8	141	15	cumbersome	cumbersome	JJ
cord-293938-40zyv1h8	141	16	and	and	CC
cord-293938-40zyv1h8	141	17	their	-PRON-	PRP$
cord-293938-40zyv1h8	141	18	preparation	preparation	NN
cord-293938-40zyv1h8	141	19	is	be	VBZ
cord-293938-40zyv1h8	141	20	time	time	NN
cord-293938-40zyv1h8	141	21	consuming	consume	VBG
cord-293938-40zyv1h8	141	22	but	but	CC
cord-293938-40zyv1h8	141	23	they	-PRON-	PRP
cord-293938-40zyv1h8	141	24	do	do	VBP
cord-293938-40zyv1h8	141	25	have	have	VB
cord-293938-40zyv1h8	141	26	an	an	DT
cord-293938-40zyv1h8	141	27	advantage	advantage	NN
cord-293938-40zyv1h8	141	28	over	over	IN
cord-293938-40zyv1h8	141	29	traditional	traditional	JJ
cord-293938-40zyv1h8	141	30	monolayer	monolayer	NN
cord-293938-40zyv1h8	141	31	cell	cell	NN
cord-293938-40zyv1h8	141	32	cultures	culture	NNS
cord-293938-40zyv1h8	141	33	when	when	WRB
cord-293938-40zyv1h8	141	34	it	-PRON-	PRP
cord-293938-40zyv1h8	141	35	comes	come	VBZ
cord-293938-40zyv1h8	141	36	to	to	IN
cord-293938-40zyv1h8	141	37	virus	virus	NN
cord-293938-40zyv1h8	141	38	-	-	HYPH
cord-293938-40zyv1h8	141	39	host	host	NN
cord-293938-40zyv1h8	141	40	interaction	interaction	NN
cord-293938-40zyv1h8	141	41	studies	study	NNS
cord-293938-40zyv1h8	141	42	.	.	.
cord-293938-40zyv1h8	142	1	Different	different	JJ
cord-293938-40zyv1h8	142	2	types	type	NNS
cord-293938-40zyv1h8	142	3	of	of	IN
cord-293938-40zyv1h8	142	4	ALI	ALI	NNP
cord-293938-40zyv1h8	142	5	cultures	culture	NNS
cord-293938-40zyv1h8	142	6	used	use	VBN
cord-293938-40zyv1h8	142	7	for	for	IN
cord-293938-40zyv1h8	142	8	virus	virus	NN
cord-293938-40zyv1h8	142	9	research	research	NN
cord-293938-40zyv1h8	142	10	are	be	VBP
cord-293938-40zyv1h8	142	11	summarized	summarize	VBN
cord-293938-40zyv1h8	142	12	in	in	IN
cord-293938-40zyv1h8	142	13	Table	Table	NNP
cord-293938-40zyv1h8	142	14	2	2	CD
cord-293938-40zyv1h8	142	15	.	.	.
cord-293938-40zyv1h8	143	1	Within	within	IN
cord-293938-40zyv1h8	143	2	the	the	DT
cord-293938-40zyv1h8	143	3	respiratory	respiratory	JJ
cord-293938-40zyv1h8	143	4	epithelium	epithelium	NN
cord-293938-40zyv1h8	143	5	the	the	DT
cord-293938-40zyv1h8	143	6	innate	innate	JJ
cord-293938-40zyv1h8	143	7	immune	immune	JJ
cord-293938-40zyv1h8	143	8	system	system	NN
cord-293938-40zyv1h8	143	9	has	have	VBZ
cord-293938-40zyv1h8	143	10	a	a	DT
cord-293938-40zyv1h8	143	11	major	major	JJ
cord-293938-40zyv1h8	143	12	protective	protective	JJ
cord-293938-40zyv1h8	143	13	role	role	NN
cord-293938-40zyv1h8	143	14	as	as	IN
cord-293938-40zyv1h8	143	15	the	the	DT
cord-293938-40zyv1h8	143	16	first	first	JJ
cord-293938-40zyv1h8	143	17	line	line	NN
cord-293938-40zyv1h8	143	18	of	of	IN
cord-293938-40zyv1h8	143	19	defense	defense	NN
cord-293938-40zyv1h8	143	20	against	against	IN
cord-293938-40zyv1h8	143	21	respiratory	respiratory	JJ
cord-293938-40zyv1h8	143	22	pathogens	pathogen	NNS
cord-293938-40zyv1h8	143	23	.	.	.
cord-293938-40zyv1h8	144	1	In	in	IN
cord-293938-40zyv1h8	144	2	particular	particular	JJ
cord-293938-40zyv1h8	144	3	,	,	,
cord-293938-40zyv1h8	144	4	the	the	DT
cord-293938-40zyv1h8	144	5	interferon	interferon	NN
cord-293938-40zyv1h8	144	6	(	(	-LRB-
cord-293938-40zyv1h8	144	7	IFN	IFN	NNP
cord-293938-40zyv1h8	144	8	)	)	-RRB-
cord-293938-40zyv1h8	144	9	system	system	NN
cord-293938-40zyv1h8	144	10	orchestrates	orchestrate	VBZ
cord-293938-40zyv1h8	144	11	hundreds	hundred	NNS
cord-293938-40zyv1h8	144	12	of	of	IN
cord-293938-40zyv1h8	144	13	different	different	JJ
cord-293938-40zyv1h8	144	14	cellular	cellular	JJ
cord-293938-40zyv1h8	144	15	effector	effector	NN
cord-293938-40zyv1h8	144	16	proteins	protein	NNS
cord-293938-40zyv1h8	144	17	that	that	WDT
cord-293938-40zyv1h8	144	18	(	(	-LRB-
cord-293938-40zyv1h8	144	19	i	i	NN
cord-293938-40zyv1h8	144	20	)	)	-RRB-
cord-293938-40zyv1h8	144	21	protect	protect	VB
cord-293938-40zyv1h8	144	22	the	the	DT
cord-293938-40zyv1h8	144	23	epithelial	epithelial	JJ
cord-293938-40zyv1h8	144	24	barrier	barrier	NN
cord-293938-40zyv1h8	144	25	by	by	IN
cord-293938-40zyv1h8	144	26	altering	alter	VBG
cord-293938-40zyv1h8	144	27	the	the	DT
cord-293938-40zyv1h8	144	28	physiological	physiological	JJ
cord-293938-40zyv1h8	144	29	and	and	CC
cord-293938-40zyv1h8	144	30	cellular	cellular	JJ
cord-293938-40zyv1h8	144	31	environment	environment	NN
cord-293938-40zyv1h8	144	32	,	,	,
cord-293938-40zyv1h8	144	33	(	(	-LRB-
cord-293938-40zyv1h8	144	34	ii	ii	NN
cord-293938-40zyv1h8	144	35	)	)	-RRB-
cord-293938-40zyv1h8	144	36	impair	impair	VBP
cord-293938-40zyv1h8	144	37	virus	virus	NN
cord-293938-40zyv1h8	144	38	propagation	propagation	NN
cord-293938-40zyv1h8	144	39	,	,	,
cord-293938-40zyv1h8	144	40	spread	spread	NN
cord-293938-40zyv1h8	144	41	and	and	CC
cord-293938-40zyv1h8	144	42	transmission	transmission	NN
cord-293938-40zyv1h8	144	43	,	,	,
cord-293938-40zyv1h8	144	44	and	and	CC
cord-293938-40zyv1h8	144	45	(	(	-LRB-
cord-293938-40zyv1h8	144	46	iii	iii	NN
cord-293938-40zyv1h8	144	47	)	)	-RRB-
cord-293938-40zyv1h8	144	48	shape	shape	VB
cord-293938-40zyv1h8	144	49	the	the	DT
cord-293938-40zyv1h8	144	50	host	host	NN
cord-293938-40zyv1h8	144	51	's	's	POS
cord-293938-40zyv1h8	144	52	adaptive	adaptive	JJ
cord-293938-40zyv1h8	144	53	immune	immune	JJ
cord-293938-40zyv1h8	144	54	response	response	NN
cord-293938-40zyv1h8	144	55	.	.	.
cord-293938-40zyv1h8	145	1	Recent	recent	JJ
cord-293938-40zyv1h8	145	2	publications	publication	NNS
cord-293938-40zyv1h8	145	3	have	have	VBP
cord-293938-40zyv1h8	145	4	demonstrated	demonstrate	VBN
cord-293938-40zyv1h8	145	5	that	that	IN
cord-293938-40zyv1h8	145	6	the	the	DT
cord-293938-40zyv1h8	145	7	innate	innate	JJ
cord-293938-40zyv1h8	145	8	immune	immune	JJ
cord-293938-40zyv1h8	145	9	system	system	NN
cord-293938-40zyv1h8	145	10	is	be	VBZ
cord-293938-40zyv1h8	145	11	functional	functional	JJ
cord-293938-40zyv1h8	145	12	in	in	IN
cord-293938-40zyv1h8	145	13	the	the	DT
cord-293938-40zyv1h8	145	14	HAE	HAE	NNP
cord-293938-40zyv1h8	145	15	cell	cell	NN
cord-293938-40zyv1h8	145	16	culture	culture	NN
cord-293938-40zyv1h8	145	17	system	system	NN
cord-293938-40zyv1h8	145	18	and	and	CC
cord-293938-40zyv1h8	145	19	that	that	IN
cord-293938-40zyv1h8	145	20	most	most	JJS
cord-293938-40zyv1h8	145	21	pathogen	pathogen	NN
cord-293938-40zyv1h8	145	22	recognition	recognition	NN
cord-293938-40zyv1h8	145	23	receptors	receptor	NNS
cord-293938-40zyv1h8	145	24	are	be	VBP
cord-293938-40zyv1h8	145	25	expressed	express	VBN
cord-293938-40zyv1h8	145	26	and	and	CC
cord-293938-40zyv1h8	145	27	up	up	RB
cord-293938-40zyv1h8	145	28	-	-	HYPH
cord-293938-40zyv1h8	145	29	regulated	regulate	VBN
cord-293938-40zyv1h8	145	30	upon	upon	IN
cord-293938-40zyv1h8	145	31	treatment	treatment	NN
cord-293938-40zyv1h8	145	32	with	with	IN
cord-293938-40zyv1h8	145	33	exogenous	exogenous	JJ
cord-293938-40zyv1h8	145	34	stimuli	stimulus	NNS
cord-293938-40zyv1h8	145	35	[	[	-LRB-
cord-293938-40zyv1h8	145	36	57	57	CD
cord-293938-40zyv1h8	145	37	,	,	,
cord-293938-40zyv1h8	145	38	81	81	CD
cord-293938-40zyv1h8	145	39	]	]	-RRB-
cord-293938-40zyv1h8	145	40	.	.	.
cord-293938-40zyv1h8	146	1	In	in	IN
cord-293938-40zyv1h8	146	2	general	general	JJ
cord-293938-40zyv1h8	146	3	,	,	,
cord-293938-40zyv1h8	146	4	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	146	5	do	do	VBP
cord-293938-40zyv1h8	146	6	not	not	RB
cord-293938-40zyv1h8	146	7	elicit	elicit	VB
cord-293938-40zyv1h8	146	8	a	a	DT
cord-293938-40zyv1h8	146	9	strong	strong	JJ
cord-293938-40zyv1h8	146	10	innate	innate	JJ
cord-293938-40zyv1h8	146	11	immune	immune	JJ
cord-293938-40zyv1h8	146	12	response	response	NN
cord-293938-40zyv1h8	146	13	in	in	IN
cord-293938-40zyv1h8	146	14	primary	primary	JJ
cord-293938-40zyv1h8	146	15	target	target	NN
cord-293938-40zyv1h8	146	16	cells	cell	NNS
cord-293938-40zyv1h8	146	17	of	of	IN
cord-293938-40zyv1h8	146	18	the	the	DT
cord-293938-40zyv1h8	146	19	human	human	JJ
cord-293938-40zyv1h8	146	20	airway	airway	NN
cord-293938-40zyv1h8	146	21	early	early	RB
cord-293938-40zyv1h8	146	22	during	during	IN
cord-293938-40zyv1h8	146	23	infection	infection	NN
cord-293938-40zyv1h8	146	24	.	.	.
cord-293938-40zyv1h8	147	1	Despite	despite	IN
cord-293938-40zyv1h8	147	2	the	the	DT
cord-293938-40zyv1h8	147	3	presence	presence	NN
cord-293938-40zyv1h8	147	4	of	of	IN
cord-293938-40zyv1h8	147	5	all	all	DT
cord-293938-40zyv1h8	147	6	major	major	JJ
cord-293938-40zyv1h8	147	7	pathogen	pathogen	NN
cord-293938-40zyv1h8	147	8	recognition	recognition	NN
cord-293938-40zyv1h8	147	9	receptors	receptor	NNS
cord-293938-40zyv1h8	147	10	,	,	,
cord-293938-40zyv1h8	147	11	no	no	DT
cord-293938-40zyv1h8	147	12	elevated	elevated	JJ
cord-293938-40zyv1h8	147	13	expression	expression	NN
cord-293938-40zyv1h8	147	14	of	of	IN
cord-293938-40zyv1h8	147	15	IFN	IFN	NNP
cord-293938-40zyv1h8	147	16	beta	beta	NN
cord-293938-40zyv1h8	147	17	,	,	,
cord-293938-40zyv1h8	147	18	pro	pro	JJ
cord-293938-40zyv1h8	147	19	-	-	JJ
cord-293938-40zyv1h8	147	20	inflammatory	inflammatory	JJ
cord-293938-40zyv1h8	147	21	cytokines	cytokine	NNS
cord-293938-40zyv1h8	147	22	or	or	CC
cord-293938-40zyv1h8	147	23	interferon	interferon	NN
cord-293938-40zyv1h8	147	24	stimulated	stimulate	VBD
cord-293938-40zyv1h8	147	25	genes	gene	NNS
cord-293938-40zyv1h8	147	26	can	can	MD
cord-293938-40zyv1h8	147	27	be	be	VB
cord-293938-40zyv1h8	147	28	observed	observe	VBN
cord-293938-40zyv1h8	147	29	up	up	IN
cord-293938-40zyv1h8	147	30	to	to	TO
cord-293938-40zyv1h8	147	31	12	12	CD
cord-293938-40zyv1h8	147	32	h	h	NN
cord-293938-40zyv1h8	147	33	post	post	NN
cord-293938-40zyv1h8	147	34	-	-	NN
cord-293938-40zyv1h8	147	35	infection	infection	NN
cord-293938-40zyv1h8	147	36	in	in	IN
cord-293938-40zyv1h8	147	37	HAEs	hae	NNS
cord-293938-40zyv1h8	147	38	infected	infect	VBN
cord-293938-40zyv1h8	147	39	with	with	IN
cord-293938-40zyv1h8	147	40	HCoV-229E	HCoV-229E	NNP
cord-293938-40zyv1h8	147	41	,	,	,
cord-293938-40zyv1h8	147	42	MERS	MERS	NNP
cord-293938-40zyv1h8	147	43	-	-	HYPH
cord-293938-40zyv1h8	147	44	or	or	CC
cord-293938-40zyv1h8	147	45	SARS	SARS	NNP
cord-293938-40zyv1h8	147	46	-	-	HYPH
cord-293938-40zyv1h8	147	47	CoVs	CoVs	NNP
cord-293938-40zyv1h8	147	48	[	[	-LRB-
cord-293938-40zyv1h8	147	49	57	57	CD
cord-293938-40zyv1h8	147	50	]	]	-RRB-
cord-293938-40zyv1h8	147	51	.	.	.
cord-293938-40zyv1h8	148	1	This	this	DT
cord-293938-40zyv1h8	148	2	is	be	VBZ
cord-293938-40zyv1h8	148	3	most	most	RBS
cord-293938-40zyv1h8	148	4	likely	likely	JJ
cord-293938-40zyv1h8	148	5	due	due	IN
cord-293938-40zyv1h8	148	6	to	to	IN
cord-293938-40zyv1h8	148	7	the	the	DT
cord-293938-40zyv1h8	148	8	intrinsic	intrinsic	JJ
cord-293938-40zyv1h8	148	9	CoV	cov	NN
cord-293938-40zyv1h8	148	10	properties	property	NNS
cord-293938-40zyv1h8	148	11	harbored	harbor	VBN
cord-293938-40zyv1h8	148	12	in	in	IN
cord-293938-40zyv1h8	148	13	the	the	DT
cord-293938-40zyv1h8	148	14	replicative	replicative	JJ
cord-293938-40zyv1h8	148	15	non	non	JJ
cord-293938-40zyv1h8	148	16	-	-	JJ
cord-293938-40zyv1h8	148	17	structural	structural	JJ
cord-293938-40zyv1h8	148	18	proteins	protein	NNS
cord-293938-40zyv1h8	148	19	that	that	WDT
cord-293938-40zyv1h8	148	20	actively	actively	RB
cord-293938-40zyv1h8	148	21	aid	aid	VBP
cord-293938-40zyv1h8	148	22	in	in	IN
cord-293938-40zyv1h8	148	23	avoiding	avoid	VBG
cord-293938-40zyv1h8	148	24	recognition	recognition	NN
cord-293938-40zyv1h8	148	25	by	by	IN
cord-293938-40zyv1h8	148	26	the	the	DT
cord-293938-40zyv1h8	148	27	host	host	NN
cord-293938-40zyv1h8	148	28	innate	innate	JJ
cord-293938-40zyv1h8	148	29	immune	immune	JJ
cord-293938-40zyv1h8	148	30	system	system	NN
cord-293938-40zyv1h8	148	31	.	.	.
cord-293938-40zyv1h8	149	1	For	for	IN
cord-293938-40zyv1h8	149	2	example	example	NN
cord-293938-40zyv1h8	149	3	,	,	,
cord-293938-40zyv1h8	149	4	the	the	DT
cord-293938-40zyv1h8	149	5	5′	5′	CD
cord-293938-40zyv1h8	149	6	termini	terminus	NNS
cord-293938-40zyv1h8	149	7	of	of	IN
cord-293938-40zyv1h8	149	8	the	the	DT
cord-293938-40zyv1h8	149	9	viral	viral	JJ
cord-293938-40zyv1h8	149	10	mRNA	mrna	NN
cord-293938-40zyv1h8	149	11	are	be	VBP
cord-293938-40zyv1h8	149	12	capped	cap	VBN
cord-293938-40zyv1h8	149	13	making	make	VBG
cord-293938-40zyv1h8	149	14	them	-PRON-	PRP
cord-293938-40zyv1h8	149	15	indistinguishable	indistinguishable	JJ
cord-293938-40zyv1h8	149	16	from	from	IN
cord-293938-40zyv1h8	149	17	the	the	DT
cord-293938-40zyv1h8	149	18	host	host	NN
cord-293938-40zyv1h8	149	19	cellular	cellular	JJ
cord-293938-40zyv1h8	149	20	mRNAs	mrnas	CD
cord-293938-40zyv1h8	150	1	and	and	CC
cord-293938-40zyv1h8	150	2	no	no	RB
cord-293938-40zyv1h8	150	3	longer	long	RBR
cord-293938-40zyv1h8	150	4	detectable	detectable	JJ
cord-293938-40zyv1h8	150	5	by	by	IN
cord-293938-40zyv1h8	150	6	cellular	cellular	JJ
cord-293938-40zyv1h8	150	7	sensors	sensor	NNS
cord-293938-40zyv1h8	150	8	.	.	.
cord-293938-40zyv1h8	151	1	Furthermore	furthermore	RB
cord-293938-40zyv1h8	151	2	,	,	,
cord-293938-40zyv1h8	151	3	CoV	cov	NN
cord-293938-40zyv1h8	151	4	replication	replication	NN
cord-293938-40zyv1h8	151	5	is	be	VBZ
cord-293938-40zyv1h8	151	6	associated	associate	VBN
cord-293938-40zyv1h8	151	7	with	with	IN
cord-293938-40zyv1h8	151	8	the	the	DT
cord-293938-40zyv1h8	151	9	appearance	appearance	NN
cord-293938-40zyv1h8	151	10	of	of	IN
cord-293938-40zyv1h8	151	11	double	double	JJ
cord-293938-40zyv1h8	151	12	membrane	membrane	NN
cord-293938-40zyv1h8	151	13	vesicles	vesicle	NNS
cord-293938-40zyv1h8	151	14	(	(	-LRB-
cord-293938-40zyv1h8	151	15	DMVs	dmv	NNS
cord-293938-40zyv1h8	151	16	)	)	-RRB-
cord-293938-40zyv1h8	151	17	in	in	IN
cord-293938-40zyv1h8	151	18	the	the	DT
cord-293938-40zyv1h8	151	19	host	host	NN
cord-293938-40zyv1h8	151	20	cell	cell	NN
cord-293938-40zyv1h8	151	21	cytoplasm	cytoplasm	NN
cord-293938-40zyv1h8	151	22	,	,	,
cord-293938-40zyv1h8	151	23	which	which	WDT
cord-293938-40zyv1h8	151	24	might	may	MD
cord-293938-40zyv1h8	151	25	serve	serve	VB
cord-293938-40zyv1h8	151	26	as	as	IN
cord-293938-40zyv1h8	151	27	a	a	DT
cord-293938-40zyv1h8	151	28	protective	protective	JJ
cord-293938-40zyv1h8	151	29	shield	shield	NN
cord-293938-40zyv1h8	151	30	for	for	IN
cord-293938-40zyv1h8	151	31	viral	viral	JJ
cord-293938-40zyv1h8	151	32	RNA	RNA	NNP
cord-293938-40zyv1h8	151	33	to	to	TO
cord-293938-40zyv1h8	151	34	prevent	prevent	VB
cord-293938-40zyv1h8	151	35	recognition	recognition	NN
cord-293938-40zyv1h8	151	36	by	by	IN
cord-293938-40zyv1h8	151	37	cytoplasmic	cytoplasmic	JJ
cord-293938-40zyv1h8	151	38	RNA	RNA	NNP
cord-293938-40zyv1h8	151	39	sensors	sensor	NNS
cord-293938-40zyv1h8	151	40	[	[	-LRB-
cord-293938-40zyv1h8	151	41	82	82	CD
cord-293938-40zyv1h8	151	42	]	]	-RRB-
cord-293938-40zyv1h8	151	43	[	[	-LRB-
cord-293938-40zyv1h8	151	44	83	83	CD
cord-293938-40zyv1h8	151	45	]	]	-RRB-
cord-293938-40zyv1h8	151	46	[	[	-LRB-
cord-293938-40zyv1h8	151	47	84	84	CD
cord-293938-40zyv1h8	151	48	]	]	-RRB-
cord-293938-40zyv1h8	151	49	[	[	-LRB-
cord-293938-40zyv1h8	151	50	85	85	CD
cord-293938-40zyv1h8	151	51	]	]	-RRB-
cord-293938-40zyv1h8	151	52	.	.	.
cord-293938-40zyv1h8	152	1	In	in	IN
cord-293938-40zyv1h8	152	2	addition	addition	NN
cord-293938-40zyv1h8	152	3	to	to	IN
cord-293938-40zyv1h8	152	4	the	the	DT
cord-293938-40zyv1h8	152	5	non	non	JJ
cord-293938-40zyv1h8	152	6	-	-	JJ
cord-293938-40zyv1h8	152	7	structural	structural	JJ
cord-293938-40zyv1h8	152	8	proteins	protein	NNS
cord-293938-40zyv1h8	152	9	,	,	,
cord-293938-40zyv1h8	152	10	various	various	JJ
cord-293938-40zyv1h8	152	11	CoV	cov	NN
cord-293938-40zyv1h8	152	12	accessory	accessory	NN
cord-293938-40zyv1h8	152	13	proteins	protein	NNS
cord-293938-40zyv1h8	152	14	have	have	VBP
cord-293938-40zyv1h8	152	15	been	be	VBN
cord-293938-40zyv1h8	152	16	discovered	discover	VBN
cord-293938-40zyv1h8	152	17	to	to	TO
cord-293938-40zyv1h8	152	18	inhibit	inhibit	VB
cord-293938-40zyv1h8	152	19	interferon	interferon	NN
cord-293938-40zyv1h8	152	20	signaling	signal	VBG
cord-293938-40zyv1h8	152	21	at	at	IN
cord-293938-40zyv1h8	152	22	different	different	JJ
cord-293938-40zyv1h8	152	23	stages	stage	NNS
cord-293938-40zyv1h8	152	24	of	of	IN
cord-293938-40zyv1h8	152	25	the	the	DT
cord-293938-40zyv1h8	152	26	host	host	NN
cord-293938-40zyv1h8	152	27	innate	innate	JJ
cord-293938-40zyv1h8	152	28	immune	immune	JJ
cord-293938-40zyv1h8	152	29	response	response	NN
cord-293938-40zyv1h8	152	30	.	.	.
cord-293938-40zyv1h8	153	1	For	for	IN
cord-293938-40zyv1h8	153	2	example	example	NN
cord-293938-40zyv1h8	153	3	,	,	,
cord-293938-40zyv1h8	153	4	MERS	MERS	NNP
cord-293938-40zyv1h8	153	5	-	-	HYPH
cord-293938-40zyv1h8	153	6	CoV	CoV	NNP
cord-293938-40zyv1h8	153	7	accessory	accessory	NN
cord-293938-40zyv1h8	153	8	protein	protein	NN
cord-293938-40zyv1h8	153	9	4a	4a	CD
cord-293938-40zyv1h8	153	10	inhibits	inhibit	VBZ
cord-293938-40zyv1h8	153	11	innate	innate	JJ
cord-293938-40zyv1h8	153	12	antiviral	antiviral	JJ
cord-293938-40zyv1h8	153	13	signaling	signal	VBG
cord-293938-40zyv1h8	153	14	by	by	IN
cord-293938-40zyv1h8	153	15	suppressing	suppress	VBG
cord-293938-40zyv1h8	153	16	the	the	DT
cord-293938-40zyv1h8	153	17	activation	activation	NN
cord-293938-40zyv1h8	153	18	of	of	IN
cord-293938-40zyv1h8	153	19	MDA5	MDA5	NNP
cord-293938-40zyv1h8	153	20	and	and	CC
cord-293938-40zyv1h8	153	21	RIGI	RIGI	NNP
cord-293938-40zyv1h8	153	22	[	[	-LRB-
cord-293938-40zyv1h8	153	23	86	86	CD
cord-293938-40zyv1h8	153	24	,	,	,
cord-293938-40zyv1h8	153	25	87	87	CD
cord-293938-40zyv1h8	153	26	]	]	-RRB-
cord-293938-40zyv1h8	153	27	whereas	whereas	IN
cord-293938-40zyv1h8	153	28	4b	4b	NNS
cord-293938-40zyv1h8	153	29	inhibits	inhibit	VBZ
cord-293938-40zyv1h8	153	30	the	the	DT
cord-293938-40zyv1h8	153	31	induction	induction	NN
cord-293938-40zyv1h8	153	32	of	of	IN
cord-293938-40zyv1h8	153	33	the	the	DT
cord-293938-40zyv1h8	153	34	IFN	IFN	NNP
cord-293938-40zyv1h8	153	35	-	-	HYPH
cord-293938-40zyv1h8	153	36	beta	beta	NN
cord-293938-40zyv1h8	153	37	promoter	promoter	NN
cord-293938-40zyv1h8	153	38	[	[	-LRB-
cord-293938-40zyv1h8	153	39	88	88	CD
cord-293938-40zyv1h8	153	40	]	]	-RRB-
cord-293938-40zyv1h8	153	41	.	.	.
cord-293938-40zyv1h8	154	1	While	while	IN
cord-293938-40zyv1h8	154	2	ORF	ORF	NNP
cord-293938-40zyv1h8	154	3	4a	4a	CD
cord-293938-40zyv1h8	154	4	and	and	CC
cord-293938-40zyv1h8	154	5	4b	4b	NNS
cord-293938-40zyv1h8	154	6	are	be	VBP
cord-293938-40zyv1h8	154	7	IFN	IFN	NNP
cord-293938-40zyv1h8	154	8	antagonists	antagonist	NNS
cord-293938-40zyv1h8	154	9	in	in	IN
cord-293938-40zyv1h8	154	10	the	the	DT
cord-293938-40zyv1h8	154	11	genome	genome	NN
cord-293938-40zyv1h8	154	12	of	of	IN
cord-293938-40zyv1h8	154	13	MERS	MERS	NNP
cord-293938-40zyv1h8	154	14	-	-	HYPH
cord-293938-40zyv1h8	154	15	CoV	CoV	NNP
cord-293938-40zyv1h8	154	16	,	,	,
cord-293938-40zyv1h8	154	17	SARS	SARS	NNP
cord-293938-40zyv1h8	154	18	-	-	HYPH
cord-293938-40zyv1h8	154	19	CoV	CoV	NNP
cord-293938-40zyv1h8	154	20	ORF3b	ORF3b	NNP
cord-293938-40zyv1h8	154	21	antagonizes	antagonize	VBZ
cord-293938-40zyv1h8	154	22	IFN	IFN	NNP
cord-293938-40zyv1h8	154	23	signaling	signal	VBG
cord-293938-40zyv1h8	154	24	through	through	IN
cord-293938-40zyv1h8	154	25	MAVS	MAVS	NNP
cord-293938-40zyv1h8	154	26	/	/	SYM
cord-293938-40zyv1h8	154	27	RIGI	RIGI	NNP
cord-293938-40zyv1h8	154	28	[	[	-LRB-
cord-293938-40zyv1h8	154	29	89	89	CD
cord-293938-40zyv1h8	154	30	]	]	-RRB-
cord-293938-40zyv1h8	154	31	.	.	.
cord-293938-40zyv1h8	155	1	Whereas	whereas	IN
cord-293938-40zyv1h8	155	2	SARS	SARS	NNP
cord-293938-40zyv1h8	155	3	-	-	HYPH
cord-293938-40zyv1h8	155	4	CoV	CoV	NNP
cord-293938-40zyv1h8	155	5	ORF6	ORF6	NNP
cord-293938-40zyv1h8	155	6	disrupts	disrupt	VBZ
cord-293938-40zyv1h8	155	7	IFN	IFN	NNP
cord-293938-40zyv1h8	155	8	signaling	signal	VBG
cord-293938-40zyv1h8	155	9	by	by	IN
cord-293938-40zyv1h8	155	10	blocking	block	VBG
cord-293938-40zyv1h8	155	11	the	the	DT
cord-293938-40zyv1h8	155	12	nuclear	nuclear	JJ
cord-293938-40zyv1h8	155	13	translocation	translocation	NN
cord-293938-40zyv1h8	155	14	of	of	IN
cord-293938-40zyv1h8	155	15	STAT1	stat1	NN
cord-293938-40zyv1h8	155	16	[	[	-LRB-
cord-293938-40zyv1h8	155	17	89	89	CD
cord-293938-40zyv1h8	155	18	,	,	,
cord-293938-40zyv1h8	155	19	90	90	CD
cord-293938-40zyv1h8	155	20	]	]	-RRB-
cord-293938-40zyv1h8	155	21	.	.	.
cord-293938-40zyv1h8	156	1	These	these	DT
cord-293938-40zyv1h8	156	2	discoveries	discovery	NNS
cord-293938-40zyv1h8	156	3	highlight	highlight	VBP
cord-293938-40zyv1h8	156	4	that	that	IN
cord-293938-40zyv1h8	156	5	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	156	6	employ	employ	VBP
cord-293938-40zyv1h8	156	7	similar	similar	JJ
cord-293938-40zyv1h8	156	8	yet	yet	CC
cord-293938-40zyv1h8	156	9	different	different	JJ
cord-293938-40zyv1h8	156	10	strategies	strategy	NNS
cord-293938-40zyv1h8	156	11	 	 	_SP
cord-293938-40zyv1h8	156	12	Despite	despite	IN
cord-293938-40zyv1h8	156	13	that	that	IN
cord-293938-40zyv1h8	156	14	respiratory	respiratory	JJ
cord-293938-40zyv1h8	156	15	infections	infection	NNS
cord-293938-40zyv1h8	156	16	with	with	IN
cord-293938-40zyv1h8	156	17	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	156	18	can	can	MD
cord-293938-40zyv1h8	156	19	result	result	VB
cord-293938-40zyv1h8	156	20	in	in	IN
cord-293938-40zyv1h8	156	21	severe	severe	JJ
cord-293938-40zyv1h8	156	22	respiratory	respiratory	JJ
cord-293938-40zyv1h8	156	23	disease	disease	NN
cord-293938-40zyv1h8	156	24	there	there	EX
cord-293938-40zyv1h8	156	25	are	be	VBP
cord-293938-40zyv1h8	156	26	currently	currently	RB
cord-293938-40zyv1h8	156	27	no	no	DT
cord-293938-40zyv1h8	156	28	effective	effective	JJ
cord-293938-40zyv1h8	156	29	prophylactic	prophylactic	JJ
cord-293938-40zyv1h8	156	30	or	or	CC
cord-293938-40zyv1h8	156	31	therapeutic	therapeutic	JJ
cord-293938-40zyv1h8	156	32	treatment	treatment	NN
cord-293938-40zyv1h8	156	33	options	option	NNS
cord-293938-40zyv1h8	156	34	available	available	JJ
cord-293938-40zyv1h8	156	35	.	.	.
cord-293938-40zyv1h8	157	1	However	however	RB
cord-293938-40zyv1h8	157	2	,	,	,
cord-293938-40zyv1h8	157	3	the	the	DT
cord-293938-40zyv1h8	157	4	emergence	emergence	NN
cord-293938-40zyv1h8	157	5	of	of	IN
cord-293938-40zyv1h8	157	6	novel	novel	NN
cord-293938-40zyv1h8	157	7	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	157	8	has	have	VBZ
cord-293938-40zyv1h8	157	9	emphasized	emphasize	VBN
cord-293938-40zyv1h8	157	10	the	the	DT
cord-293938-40zyv1h8	157	11	need	need	NN
cord-293938-40zyv1h8	157	12	to	to	TO
cord-293938-40zyv1h8	157	13	develop	develop	VB
cord-293938-40zyv1h8	157	14	effective	effective	JJ
cord-293938-40zyv1h8	157	15	treatment	treatment	NN
cord-293938-40zyv1h8	157	16	options	option	NNS
cord-293938-40zyv1h8	157	17	.	.	.
cord-293938-40zyv1h8	158	1	For	for	IN
cord-293938-40zyv1h8	158	2	example	example	NN
cord-293938-40zyv1h8	158	3	,	,	,
cord-293938-40zyv1h8	158	4	vaccines	vaccine	NNS
cord-293938-40zyv1h8	158	5	using	use	VBG
cord-293938-40zyv1h8	158	6	the	the	DT
cord-293938-40zyv1h8	158	7	spike	spike	NN
cord-293938-40zyv1h8	158	8	proteins	protein	NNS
cord-293938-40zyv1h8	158	9	of	of	IN
cord-293938-40zyv1h8	158	10	both	both	DT
cord-293938-40zyv1h8	158	11	SARS	SARS	NNP
cord-293938-40zyv1h8	158	12	-	-	:
cord-293938-40zyv1h8	158	13	and	and	CC
cord-293938-40zyv1h8	158	14	MERS	MERS	NNP
cord-293938-40zyv1h8	158	15	-	-	HYPH
cord-293938-40zyv1h8	158	16	CoVs	CoVs	NNP
cord-293938-40zyv1h8	158	17	have	have	VBP
cord-293938-40zyv1h8	158	18	proven	prove	VBN
cord-293938-40zyv1h8	158	19	protective	protective	JJ
cord-293938-40zyv1h8	158	20	in	in	IN
cord-293938-40zyv1h8	158	21	animal	animal	NN
cord-293938-40zyv1h8	158	22	models	model	NNS
cord-293938-40zyv1h8	158	23	[	[	-LRB-
cord-293938-40zyv1h8	158	24	91	91	CD
cord-293938-40zyv1h8	158	25	,	,	,
cord-293938-40zyv1h8	158	26	92	92	CD
cord-293938-40zyv1h8	158	27	]	]	-RRB-
cord-293938-40zyv1h8	158	28	suggesting	suggest	VBG
cord-293938-40zyv1h8	158	29	that	that	IN
cord-293938-40zyv1h8	158	30	a	a	DT
cord-293938-40zyv1h8	158	31	vaccine	vaccine	NN
cord-293938-40zyv1h8	158	32	against	against	IN
cord-293938-40zyv1h8	158	33	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	158	34	for	for	IN
cord-293938-40zyv1h8	158	35	human	human	JJ
cord-293938-40zyv1h8	158	36	use	use	NN
cord-293938-40zyv1h8	158	37	might	may	MD
cord-293938-40zyv1h8	158	38	be	be	VB
cord-293938-40zyv1h8	158	39	achievable	achievable	JJ
cord-293938-40zyv1h8	158	40	.	.	.
cord-293938-40zyv1h8	159	1	Additionally	additionally	RB
cord-293938-40zyv1h8	159	2	,	,	,
cord-293938-40zyv1h8	159	3	various	various	JJ
cord-293938-40zyv1h8	159	4	drugs	drug	NNS
cord-293938-40zyv1h8	159	5	that	that	WDT
cord-293938-40zyv1h8	159	6	inhibit	inhibit	VBP
cord-293938-40zyv1h8	159	7	HCoV	hcov	NN
cord-293938-40zyv1h8	159	8	infection	infection	NN
cord-293938-40zyv1h8	159	9	at	at	IN
cord-293938-40zyv1h8	159	10	different	different	JJ
cord-293938-40zyv1h8	159	11	stages	stage	NNS
cord-293938-40zyv1h8	159	12	of	of	IN
cord-293938-40zyv1h8	159	13	the	the	DT
cord-293938-40zyv1h8	159	14	replication	replication	NN
cord-293938-40zyv1h8	159	15	cycle	cycle	NN
cord-293938-40zyv1h8	159	16	have	have	VBP
cord-293938-40zyv1h8	159	17	been	be	VBN
cord-293938-40zyv1h8	159	18	reported	report	VBN
cord-293938-40zyv1h8	159	19	and	and	CC
cord-293938-40zyv1h8	159	20	some	some	DT
cord-293938-40zyv1h8	159	21	could	could	MD
cord-293938-40zyv1h8	159	22	potentially	potentially	RB
cord-293938-40zyv1h8	159	23	serve	serve	VB
cord-293938-40zyv1h8	159	24	as	as	IN
cord-293938-40zyv1h8	159	25	treatment	treatment	NN
cord-293938-40zyv1h8	159	26	options	option	NNS
cord-293938-40zyv1h8	159	27	for	for	IN
cord-293938-40zyv1h8	159	28	HCoV	hcov	NN
cord-293938-40zyv1h8	159	29	associated	associate	VBN
cord-293938-40zyv1h8	159	30	severe	severe	JJ
cord-293938-40zyv1h8	159	31	respiratory	respiratory	JJ
cord-293938-40zyv1h8	159	32	disease	disease	NN
cord-293938-40zyv1h8	159	33	.	.	.
cord-293938-40zyv1h8	160	1	For	for	IN
cord-293938-40zyv1h8	160	2	example	example	NN
cord-293938-40zyv1h8	160	3	,	,	,
cord-293938-40zyv1h8	160	4	patients	patient	NNS
cord-293938-40zyv1h8	160	5	presenting	present	VBG
cord-293938-40zyv1h8	160	6	with	with	IN
cord-293938-40zyv1h8	160	7	severe	severe	JJ
cord-293938-40zyv1h8	160	8	respiratory	respiratory	JJ
cord-293938-40zyv1h8	160	9	disease	disease	NN
cord-293938-40zyv1h8	160	10	,	,	,
cord-293938-40zyv1h8	160	11	caused	cause	VBN
cord-293938-40zyv1h8	160	12	by	by	IN
cord-293938-40zyv1h8	160	13	SARS	SARS	NNP
cord-293938-40zyv1h8	160	14	-	-	:
cord-293938-40zyv1h8	160	15	or	or	CC
cord-293938-40zyv1h8	160	16	MERS	MERS	NNP
cord-293938-40zyv1h8	160	17	-	-	HYPH
cord-293938-40zyv1h8	160	18	CoVs	CoVs	NNP
cord-293938-40zyv1h8	160	19	,	,	,
cord-293938-40zyv1h8	160	20	are	be	VBP
cord-293938-40zyv1h8	160	21	generally	generally	RB
cord-293938-40zyv1h8	160	22	treated	treat	VBN
cord-293938-40zyv1h8	160	23	with	with	IN
cord-293938-40zyv1h8	160	24	steroids	steroid	NNS
cord-293938-40zyv1h8	160	25	and	and	CC
cord-293938-40zyv1h8	160	26	interferon	interferon	NN
cord-293938-40zyv1h8	160	27	,	,	,
cord-293938-40zyv1h8	160	28	sometimes	sometimes	RB
cord-293938-40zyv1h8	160	29	in	in	IN
cord-293938-40zyv1h8	160	30	combination	combination	NN
cord-293938-40zyv1h8	160	31	with	with	IN
cord-293938-40zyv1h8	160	32	the	the	DT
cord-293938-40zyv1h8	160	33	antiviral	antiviral	JJ
cord-293938-40zyv1h8	160	34	drug	drug	NN
cord-293938-40zyv1h8	160	35	Ribavirin	Ribavirin	NNP
cord-293938-40zyv1h8	160	36	[	[	-LRB-
cord-293938-40zyv1h8	160	37	93	93	CD
cord-293938-40zyv1h8	160	38	]	]	-RRB-
cord-293938-40zyv1h8	160	39	[	[	-LRB-
cord-293938-40zyv1h8	160	40	94	94	CD
cord-293938-40zyv1h8	160	41	]	]	-RRB-
cord-293938-40zyv1h8	160	42	[	[	-LRB-
cord-293938-40zyv1h8	160	43	95	95	CD
cord-293938-40zyv1h8	160	44	]	]	-RRB-
cord-293938-40zyv1h8	160	45	[	[	-LRB-
cord-293938-40zyv1h8	160	46	96	96	CD
cord-293938-40zyv1h8	160	47	]	]	-RRB-
cord-293938-40zyv1h8	160	48	.	.	.
cord-293938-40zyv1h8	161	1	This	this	DT
cord-293938-40zyv1h8	161	2	treatment	treatment	NN
cord-293938-40zyv1h8	161	3	,	,	,
cord-293938-40zyv1h8	161	4	however	however	RB
cord-293938-40zyv1h8	161	5	,	,	,
cord-293938-40zyv1h8	161	6	is	be	VBZ
cord-293938-40zyv1h8	161	7	not	not	RB
cord-293938-40zyv1h8	161	8	especially	especially	RB
cord-293938-40zyv1h8	161	9	effective	effective	JJ
cord-293938-40zyv1h8	161	10	highlighting	highlight	VBG
cord-293938-40zyv1h8	161	11	the	the	DT
cord-293938-40zyv1h8	161	12	need	need	NN
cord-293938-40zyv1h8	161	13	for	for	IN
cord-293938-40zyv1h8	161	14	HCoV	hcov	ADD
cord-293938-40zyv1h8	161	15	specific	specific	JJ
cord-293938-40zyv1h8	161	16	antivirals	antiviral	NNS
cord-293938-40zyv1h8	161	17	.	.	.
cord-293938-40zyv1h8	162	1	Many	many	JJ
cord-293938-40zyv1h8	162	2	different	different	JJ
cord-293938-40zyv1h8	162	3	compounds	compound	NNS
cord-293938-40zyv1h8	162	4	have	have	VBP
cord-293938-40zyv1h8	162	5	been	be	VBN
cord-293938-40zyv1h8	162	6	determined	determine	VBN
cord-293938-40zyv1h8	162	7	to	to	TO
cord-293938-40zyv1h8	162	8	have	have	VB
cord-293938-40zyv1h8	162	9	anti	anti	JJ
cord-293938-40zyv1h8	162	10	-	-	JJ
cord-293938-40zyv1h8	162	11	HCoV	hcov	JJ
cord-293938-40zyv1h8	162	12	activity	activity	NN
cord-293938-40zyv1h8	162	13	.	.	.
cord-293938-40zyv1h8	163	1	For	for	IN
cord-293938-40zyv1h8	163	2	example	example	NN
cord-293938-40zyv1h8	163	3	,	,	,
cord-293938-40zyv1h8	163	4	protease	protease	NN
cord-293938-40zyv1h8	163	5	inhibitors	inhibitor	NNS
cord-293938-40zyv1h8	163	6	which	which	WDT
cord-293938-40zyv1h8	163	7	suppress	suppress	VBP
cord-293938-40zyv1h8	163	8	HCoV	HCoV	NNP
cord-293938-40zyv1h8	163	9	entry	entry	NN
cord-293938-40zyv1h8	163	10	[	[	-LRB-
cord-293938-40zyv1h8	163	11	97	97	CD
cord-293938-40zyv1h8	163	12	]	]	-RRB-
cord-293938-40zyv1h8	163	13	[	[	-LRB-
cord-293938-40zyv1h8	163	14	98	98	CD
cord-293938-40zyv1h8	163	15	]	]	-RRB-
cord-293938-40zyv1h8	163	16	[	[	-LRB-
cord-293938-40zyv1h8	163	17	99	99	CD
cord-293938-40zyv1h8	163	18	]	]	-RRB-
cord-293938-40zyv1h8	163	19	,	,	,
cord-293938-40zyv1h8	163	20	Cyclosporin	Cyclosporin	NNP
cord-293938-40zyv1h8	163	21	A	A	NNP
cord-293938-40zyv1h8	163	22	(	(	-LRB-
cord-293938-40zyv1h8	163	23	CsA	csa	NN
cord-293938-40zyv1h8	163	24	)	)	-RRB-
cord-293938-40zyv1h8	163	25	treatment	treatment	NN
cord-293938-40zyv1h8	163	26	blocks	block	VBZ
cord-293938-40zyv1h8	163	27	the	the	DT
cord-293938-40zyv1h8	163	28	replication	replication	NN
cord-293938-40zyv1h8	163	29	of	of	IN
cord-293938-40zyv1h8	163	30	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	163	31	from	from	IN
cord-293938-40zyv1h8	163	32	all	all	DT
cord-293938-40zyv1h8	163	33	subgroups	subgroup	NNS
cord-293938-40zyv1h8	163	34	[	[	-LRB-
cord-293938-40zyv1h8	163	35	100	100	CD
cord-293938-40zyv1h8	163	36	]	]	-RRB-
cord-293938-40zyv1h8	163	37	and	and	CC
cord-293938-40zyv1h8	163	38	non	non	JJ
cord-293938-40zyv1h8	163	39	-	-	JJ
cord-293938-40zyv1h8	163	40	immunosuppressive	immunosuppressive	JJ
cord-293938-40zyv1h8	163	41	derivatives	derivative	NNS
cord-293938-40zyv1h8	163	42	of	of	IN
cord-293938-40zyv1h8	163	43	CsA	CsA	NNP
cord-293938-40zyv1h8	163	44	represent	represent	VBP
cord-293938-40zyv1h8	163	45	a	a	DT
cord-293938-40zyv1h8	163	46	possible	possible	JJ
cord-293938-40zyv1h8	163	47	therapeutic	therapeutic	JJ
cord-293938-40zyv1h8	163	48	option	option	NN
cord-293938-40zyv1h8	163	49	for	for	IN
cord-293938-40zyv1h8	163	50	both	both	CC
cord-293938-40zyv1h8	163	51	human	human	JJ
cord-293938-40zyv1h8	163	52	and	and	CC
cord-293938-40zyv1h8	163	53	animal	animal	NN
cord-293938-40zyv1h8	163	54	CoV	cov	NN
cord-293938-40zyv1h8	163	55	infections	infection	NNS
cord-293938-40zyv1h8	163	56	.	.	.
cord-293938-40zyv1h8	164	1	HCoV	HCoV	NNP
cord-293938-40zyv1h8	164	2	infection	infection	NN
cord-293938-40zyv1h8	164	3	can	can	MD
cord-293938-40zyv1h8	164	4	also	also	RB
cord-293938-40zyv1h8	164	5	be	be	VB
cord-293938-40zyv1h8	164	6	inhibited	inhibit	VBN
cord-293938-40zyv1h8	164	7	by	by	IN
cord-293938-40zyv1h8	164	8	pre	pre	JJ
cord-293938-40zyv1h8	164	9	-	-	JJ
cord-293938-40zyv1h8	164	10	treating	treat	VBG
cord-293938-40zyv1h8	164	11	HAE	HAE	NNP
cord-293938-40zyv1h8	164	12	cultures	culture	NNS
cord-293938-40zyv1h8	164	13	with	with	IN
cord-293938-40zyv1h8	164	14	either	either	DT
cord-293938-40zyv1h8	164	15	recombinant	recombinant	JJ
cord-293938-40zyv1h8	164	16	IFN	IFN	NNP
cord-293938-40zyv1h8	164	17	alpha	alpha	NN
cord-293938-40zyv1h8	164	18	or	or	CC
cord-293938-40zyv1h8	164	19	lambda	lambda	NN
cord-293938-40zyv1h8	164	20	[	[	-LRB-
cord-293938-40zyv1h8	164	21	57	57	CD
cord-293938-40zyv1h8	164	22	]	]	-RRB-
cord-293938-40zyv1h8	164	23	.	.	.
cord-293938-40zyv1h8	165	1	Similar	similar	JJ
cord-293938-40zyv1h8	165	2	effect	effect	NN
cord-293938-40zyv1h8	165	3	has	have	VBZ
cord-293938-40zyv1h8	165	4	also	also	RB
cord-293938-40zyv1h8	165	5	been	be	VBN
cord-293938-40zyv1h8	165	6	shown	show	VBN
cord-293938-40zyv1h8	165	7	for	for	IN
cord-293938-40zyv1h8	165	8	recombinant	recombinant	JJ
cord-293938-40zyv1h8	165	9	IFN	IFN	NNP
cord-293938-40zyv1h8	165	10	alpha	alpha	NN
cord-293938-40zyv1h8	165	11	and	and	CC
cord-293938-40zyv1h8	165	12	beta	beta	NN
cord-293938-40zyv1h8	165	13	which	which	WDT
cord-293938-40zyv1h8	165	14	could	could	MD
cord-293938-40zyv1h8	165	15	inhibit	inhibit	VB
cord-293938-40zyv1h8	165	16	MERS	MERS	NNP
cord-293938-40zyv1h8	165	17	-	-	HYPH
cord-293938-40zyv1h8	165	18	CoV	CoV	NNP
cord-293938-40zyv1h8	165	19	in	in	IN
cord-293938-40zyv1h8	165	20	ex	ex	FW
cord-293938-40zyv1h8	165	21	vivo	vivo	NN
cord-293938-40zyv1h8	165	22	lung	lung	NN
cord-293938-40zyv1h8	165	23	cultures	culture	NNS
cord-293938-40zyv1h8	165	24	[	[	-LRB-
cord-293938-40zyv1h8	165	25	53	53	CD
cord-293938-40zyv1h8	165	26	]	]	-RRB-
cord-293938-40zyv1h8	165	27	.	.	.
cord-293938-40zyv1h8	166	1	As	as	IN
cord-293938-40zyv1h8	166	2	previously	previously	RB
cord-293938-40zyv1h8	166	3	described	describe	VBN
cord-293938-40zyv1h8	166	4	,	,	,
cord-293938-40zyv1h8	166	5	IFN	IFN	NNP
cord-293938-40zyv1h8	166	6	treatment	treatment	NN
cord-293938-40zyv1h8	166	7	of	of	IN
cord-293938-40zyv1h8	166	8	active	active	JJ
cord-293938-40zyv1h8	166	9	HCoV	hcov	NN
cord-293938-40zyv1h8	166	10	infection	infection	NN
cord-293938-40zyv1h8	166	11	is	be	VBZ
cord-293938-40zyv1h8	166	12	not	not	RB
cord-293938-40zyv1h8	166	13	particularly	particularly	RB
cord-293938-40zyv1h8	166	14	effective	effective	JJ
cord-293938-40zyv1h8	166	15	in	in	IN
cord-293938-40zyv1h8	166	16	vivo	vivo	NN
cord-293938-40zyv1h8	166	17	.	.	.
cord-293938-40zyv1h8	167	1	Therefore	therefore	RB
cord-293938-40zyv1h8	167	2	,	,	,
cord-293938-40zyv1h8	167	3	the	the	DT
cord-293938-40zyv1h8	167	4	use	use	NN
cord-293938-40zyv1h8	167	5	of	of	IN
cord-293938-40zyv1h8	167	6	IFN	IFN	NNP
cord-293938-40zyv1h8	167	7	in	in	IN
cord-293938-40zyv1h8	167	8	humans	human	NNS
cord-293938-40zyv1h8	167	9	might	may	MD
cord-293938-40zyv1h8	167	10	be	be	VB
cord-293938-40zyv1h8	167	11	limited	limit	VBN
cord-293938-40zyv1h8	167	12	to	to	IN
cord-293938-40zyv1h8	167	13	prophylactic	prophylactic	JJ
cord-293938-40zyv1h8	167	14	treatment	treatment	NN
cord-293938-40zyv1h8	167	15	of	of	IN
cord-293938-40zyv1h8	167	16	exposed	expose	VBN
cord-293938-40zyv1h8	167	17	persons	person	NNS
cord-293938-40zyv1h8	167	18	and/or	and/or	CC
cord-293938-40zyv1h8	167	19	health	health	NN
cord-293938-40zyv1h8	167	20	care	care	NN
cord-293938-40zyv1h8	167	21	workers	worker	NNS
cord-293938-40zyv1h8	167	22	treating	treat	VBG
cord-293938-40zyv1h8	167	23	infected	infect	VBN
cord-293938-40zyv1h8	167	24	patients	patient	NNS
cord-293938-40zyv1h8	167	25	.	.	.
cord-293938-40zyv1h8	168	1	Screenings	screening	NNS
cord-293938-40zyv1h8	168	2	of	of	IN
cord-293938-40zyv1h8	168	3	compound	compound	NN
cord-293938-40zyv1h8	168	4	libraries	library	NNS
cord-293938-40zyv1h8	168	5	have	have	VBP
cord-293938-40zyv1h8	168	6	also	also	RB
cord-293938-40zyv1h8	168	7	resulted	result	VBN
cord-293938-40zyv1h8	168	8	in	in	IN
cord-293938-40zyv1h8	168	9	the	the	DT
cord-293938-40zyv1h8	168	10	identification	identification	NN
cord-293938-40zyv1h8	168	11	of	of	IN
cord-293938-40zyv1h8	168	12	some	some	DT
cord-293938-40zyv1h8	168	13	HCoV	hcov	CD
cord-293938-40zyv1h8	168	14	specific	specific	JJ
cord-293938-40zyv1h8	168	15	antivirals	antiviral	NNS
cord-293938-40zyv1h8	168	16	.	.	.
cord-293938-40zyv1h8	169	1	For	for	IN
cord-293938-40zyv1h8	169	2	example	example	NN
cord-293938-40zyv1h8	169	3	,	,	,
cord-293938-40zyv1h8	169	4	a	a	DT
cord-293938-40zyv1h8	169	5	novel	novel	JJ
cord-293938-40zyv1h8	169	6	small	small	JJ
cord-293938-40zyv1h8	169	7	compound	compound	NN
cord-293938-40zyv1h8	169	8	inhibitor	inhibitor	NN
cord-293938-40zyv1h8	169	9	(	(	-LRB-
cord-293938-40zyv1h8	169	10	K22	K22	NNP
cord-293938-40zyv1h8	169	11	)	)	-RRB-
cord-293938-40zyv1h8	169	12	has	have	VBZ
cord-293938-40zyv1h8	169	13	been	be	VBN
cord-293938-40zyv1h8	169	14	identified	identify	VBN
cord-293938-40zyv1h8	169	15	,	,	,
cord-293938-40zyv1h8	169	16	and	and	CC
cord-293938-40zyv1h8	169	17	showed	show	VBD
cord-293938-40zyv1h8	169	18	to	to	TO
cord-293938-40zyv1h8	169	19	be	be	VB
cord-293938-40zyv1h8	169	20	effective	effective	JJ
cord-293938-40zyv1h8	169	21	against	against	IN
cord-293938-40zyv1h8	169	22	a	a	DT
cord-293938-40zyv1h8	169	23	broad	broad	JJ
cord-293938-40zyv1h8	169	24	spectrum	spectrum	NN
cord-293938-40zyv1h8	169	25	of	of	IN
cord-293938-40zyv1h8	169	26	CoVs	CoVs	NNP
cord-293938-40zyv1h8	169	27	and	and	CC
cord-293938-40zyv1h8	169	28	could	could	MD
cord-293938-40zyv1h8	169	29	inhibit	inhibit	VB
cord-293938-40zyv1h8	169	30	both	both	DT
cord-293938-40zyv1h8	169	31	HCoV-229E	HCoV-229E	NNS
cord-293938-40zyv1h8	169	32	and	and	CC
cord-293938-40zyv1h8	169	33	MERS	MERS	NNP
cord-293938-40zyv1h8	169	34	-	-	HYPH
cord-293938-40zyv1h8	169	35	CoV	CoV	NNP
cord-293938-40zyv1h8	169	36	in	in	IN
cord-293938-40zyv1h8	169	37	HAE	HAE	NNP
cord-293938-40zyv1h8	169	38	cultures	culture	NNS
cord-293938-40zyv1h8	169	39	[	[	-LRB-
cord-293938-40zyv1h8	169	40	101	101	CD
cord-293938-40zyv1h8	169	41	]	]	-RRB-
cord-293938-40zyv1h8	169	42	.	.	.
cord-293938-40zyv1h8	170	1	Additionally	additionally	RB
cord-293938-40zyv1h8	170	2	,	,	,
cord-293938-40zyv1h8	170	3	HCoV	HCoV	NNP
cord-293938-40zyv1h8	170	4	-	-	HYPH
cord-293938-40zyv1h8	170	5	NL63	NL63	NNP
cord-293938-40zyv1h8	170	6	has	have	VBZ
cord-293938-40zyv1h8	170	7	been	be	VBN
cord-293938-40zyv1h8	170	8	inhibited	inhibit	VBN
cord-293938-40zyv1h8	170	9	in	in	IN
cord-293938-40zyv1h8	170	10	HAE	HAE	NNP
cord-293938-40zyv1h8	170	11	cultures	culture	NNS
cord-293938-40zyv1h8	170	12	with	with	IN
cord-293938-40zyv1h8	170	13	polymer	polymer	NN
cord-293938-40zyv1h8	170	14	-	-	HYPH
cord-293938-40zyv1h8	170	15	based	base	VBN
cord-293938-40zyv1h8	170	16	compounds	compound	NNS
cord-293938-40zyv1h8	170	17	[	[	-LRB-
cord-293938-40zyv1h8	170	18	102	102	CD
cord-293938-40zyv1h8	170	19	]	]	-RRB-
cord-293938-40zyv1h8	170	20	.	.	.
cord-293938-40zyv1h8	171	1	To	to	IN
cord-293938-40zyv1h8	171	2	date	date	NN
cord-293938-40zyv1h8	171	3	,	,	,
cord-293938-40zyv1h8	171	4	most	most	JJS
cord-293938-40zyv1h8	171	5	treatment	treatment	NN
cord-293938-40zyv1h8	171	6	and	and	CC
cord-293938-40zyv1h8	171	7	inhibitor	inhibitor	NN
cord-293938-40zyv1h8	171	8	studies	study	NNS
cord-293938-40zyv1h8	171	9	have	have	VBP
cord-293938-40zyv1h8	171	10	been	be	VBN
cord-293938-40zyv1h8	171	11	conducted	conduct	VBN
cord-293938-40zyv1h8	171	12	in	in	IN
cord-293938-40zyv1h8	171	13	HCoV	HCoV	NNP
cord-293938-40zyv1h8	171	14	susceptible	susceptible	JJ
cord-293938-40zyv1h8	171	15	cell	cell	NN
cord-293938-40zyv1h8	171	16	lines	line	NNS
cord-293938-40zyv1h8	171	17	.	.	.
cord-293938-40zyv1h8	172	1	However	however	RB
cord-293938-40zyv1h8	172	2	,	,	,
cord-293938-40zyv1h8	172	3	the	the	DT
cord-293938-40zyv1h8	172	4	HAE	HAE	NNP
cord-293938-40zyv1h8	172	5	cultures	culture	NNS
cord-293938-40zyv1h8	172	6	represent	represent	VBP
cord-293938-40zyv1h8	172	7	an	an	DT
cord-293938-40zyv1h8	172	8	ideal	ideal	JJ
cord-293938-40zyv1h8	172	9	system	system	NN
cord-293938-40zyv1h8	172	10	to	to	TO
cord-293938-40zyv1h8	172	11	test	test	VB
cord-293938-40zyv1h8	172	12	the	the	DT
cord-293938-40zyv1h8	172	13	application	application	NN
cord-293938-40zyv1h8	172	14	and	and	CC
cord-293938-40zyv1h8	172	15	efficacy	efficacy	NN
cord-293938-40zyv1h8	172	16	of	of	IN
cord-293938-40zyv1h8	172	17	those	those	DT
cord-293938-40zyv1h8	172	18	already	already	RB
cord-293938-40zyv1h8	172	19	identified	identify	VBN
cord-293938-40zyv1h8	172	20	,	,	,
cord-293938-40zyv1h8	172	21	and	and	CC
cord-293938-40zyv1h8	172	22	new	new	JJ
cord-293938-40zyv1h8	172	23	,	,	,
cord-293938-40zyv1h8	172	24	antiviral	antiviral	JJ
cord-293938-40zyv1h8	172	25	compounds	compound	NNS
cord-293938-40zyv1h8	172	26	against	against	IN
cord-293938-40zyv1h8	172	27	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	172	28	in	in	IN
cord-293938-40zyv1h8	172	29	cells	cell	NNS
cord-293938-40zyv1h8	172	30	that	that	WDT
cord-293938-40zyv1h8	172	31	represent	represent	VBP
cord-293938-40zyv1h8	172	32	the	the	DT
cord-293938-40zyv1h8	172	33	primary	primary	JJ
cord-293938-40zyv1h8	172	34	site	site	NN
cord-293938-40zyv1h8	172	35	of	of	IN
cord-293938-40zyv1h8	172	36	replication	replication	NN
cord-293938-40zyv1h8	172	37	.	.	.
cord-293938-40zyv1h8	173	1	Furthermore	furthermore	RB
cord-293938-40zyv1h8	173	2	,	,	,
cord-293938-40zyv1h8	173	3	the	the	DT
cord-293938-40zyv1h8	173	4	HAE	HAE	NNP
cord-293938-40zyv1h8	173	5	cultures	culture	NNS
cord-293938-40zyv1h8	173	6	are	be	VBP
cord-293938-40zyv1h8	173	7	heterogenous	heterogenous	JJ
cord-293938-40zyv1h8	173	8	,	,	,
cord-293938-40zyv1h8	173	9	containing	contain	VBG
cord-293938-40zyv1h8	173	10	many	many	JJ
cord-293938-40zyv1h8	173	11	different	different	JJ
cord-293938-40zyv1h8	173	12	cellular	cellular	JJ
cord-293938-40zyv1h8	173	13	sub	sub	NN
cord-293938-40zyv1h8	173	14	-	-	NNS
cord-293938-40zyv1h8	173	15	populations	population	NNS
cord-293938-40zyv1h8	173	16	,	,	,
cord-293938-40zyv1h8	173	17	and	and	CC
cord-293938-40zyv1h8	173	18	would	would	MD
cord-293938-40zyv1h8	173	19	allow	allow	VB
cord-293938-40zyv1h8	173	20	for	for	IN
cord-293938-40zyv1h8	173	21	the	the	DT
cord-293938-40zyv1h8	173	22	evaluation	evaluation	NN
cord-293938-40zyv1h8	173	23	of	of	IN
cord-293938-40zyv1h8	173	24	compound	compound	NN
cord-293938-40zyv1h8	173	25	toxicity	toxicity	NN
cord-293938-40zyv1h8	173	26	and	and	CC
cord-293938-40zyv1h8	173	27	effect	effect	NN
cord-293938-40zyv1h8	173	28	in	in	IN
cord-293938-40zyv1h8	173	29	a	a	DT
cord-293938-40zyv1h8	173	30	differentiated	differentiated	JJ
cord-293938-40zyv1h8	173	31	layer	layer	NN
cord-293938-40zyv1h8	173	32	similar	similar	JJ
cord-293938-40zyv1h8	173	33	to	to	IN
cord-293938-40zyv1h8	173	34	human	human	JJ
cord-293938-40zyv1h8	173	35	airway	airway	NN
cord-293938-40zyv1h8	173	36	epithelium	epithelium	NN
cord-293938-40zyv1h8	173	37	.	.	.
cord-293938-40zyv1h8	174	1	Compounds	compound	NNS
cord-293938-40zyv1h8	174	2	already	already	RB
cord-293938-40zyv1h8	174	3	shown	show	VBN
cord-293938-40zyv1h8	174	4	to	to	TO
cord-293938-40zyv1h8	174	5	inhibit	inhibit	VB
cord-293938-40zyv1h8	174	6	HCoVs	hcovs	NN
cord-293938-40zyv1h8	174	7	in	in	IN
cord-293938-40zyv1h8	174	8	cell	cell	NN
cord-293938-40zyv1h8	174	9	lines	line	NNS
cord-293938-40zyv1h8	174	10	should	should	MD
cord-293938-40zyv1h8	174	11	be	be	VB
cord-293938-40zyv1h8	174	12	applied	apply	VBN
cord-293938-40zyv1h8	174	13	to	to	IN
cord-293938-40zyv1h8	174	14	HAE	HAE	NNP
cord-293938-40zyv1h8	174	15	cultures	culture	NNS
cord-293938-40zyv1h8	174	16	as	as	RB
cord-293938-40zyv1h8	174	17	well	well	RB
cord-293938-40zyv1h8	174	18	before	before	IN
cord-293938-40zyv1h8	174	19	any	any	DT
cord-293938-40zyv1h8	174	20	animal	animal	NN
cord-293938-40zyv1h8	174	21	or	or	CC
cord-293938-40zyv1h8	174	22	human	human	JJ
cord-293938-40zyv1h8	174	23	trials	trial	NNS
cord-293938-40zyv1h8	174	24	.	.	.
cord-293938-40zyv1h8	175	1	HCoV	HCoV	NNP
cord-293938-40zyv1h8	175	2	induced	induce	VBN
cord-293938-40zyv1h8	175	3	respiratory	respiratory	JJ
cord-293938-40zyv1h8	175	4	diseases	disease	NNS
cord-293938-40zyv1h8	175	5	are	be	VBP
cord-293938-40zyv1h8	175	6	of	of	IN
cord-293938-40zyv1h8	175	7	both	both	CC
cord-293938-40zyv1h8	175	8	medical	medical	JJ
cord-293938-40zyv1h8	175	9	and	and	CC
cord-293938-40zyv1h8	175	10	socio	socio	JJ
cord-293938-40zyv1h8	175	11	-	-	HYPH
cord-293938-40zyv1h8	175	12	economic	economic	JJ
cord-293938-40zyv1h8	175	13	importance	importance	NN
cord-293938-40zyv1h8	175	14	.	.	.
cord-293938-40zyv1h8	176	1	The	the	DT
cord-293938-40zyv1h8	176	2	emergence	emergence	NN
cord-293938-40zyv1h8	176	3	of	of	IN
cord-293938-40zyv1h8	176	4	SARS	SARS	NNP
cord-293938-40zyv1h8	176	5	-	-	:
cord-293938-40zyv1h8	176	6	and	and	CC
cord-293938-40zyv1h8	176	7	MERS	MERS	NNP
cord-293938-40zyv1h8	176	8	-	-	HYPH
cord-293938-40zyv1h8	176	9	CoV	CoV	NNP
cord-293938-40zyv1h8	176	10	and	and	CC
cord-293938-40zyv1h8	176	11	the	the	DT
cord-293938-40zyv1h8	176	12	yearly	yearly	JJ
cord-293938-40zyv1h8	176	13	circulation	circulation	NN
cord-293938-40zyv1h8	176	14	of	of	IN
cord-293938-40zyv1h8	176	15	the	the	DT
cord-293938-40zyv1h8	176	16	four	four	CD
cord-293938-40zyv1h8	176	17	common	common	JJ
cord-293938-40zyv1h8	176	18	HCoVs	hcovs	CD
cord-293938-40zyv1h8	176	19	highlight	highlight	VBP
cord-293938-40zyv1h8	176	20	the	the	DT
cord-293938-40zyv1h8	176	21	importance	importance	NN
cord-293938-40zyv1h8	176	22	of	of	IN
cord-293938-40zyv1h8	176	23	elucidating	elucidate	VBG
cord-293938-40zyv1h8	176	24	the	the	DT
cord-293938-40zyv1h8	176	25	different	different	JJ
cord-293938-40zyv1h8	176	26	mechanisms	mechanism	NNS
cord-293938-40zyv1h8	176	27	employed	employ	VBN
cord-293938-40zyv1h8	176	28	by	by	IN
cord-293938-40zyv1h8	176	29	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	176	30	to	to	TO
cord-293938-40zyv1h8	176	31	evade	evade	VB
cord-293938-40zyv1h8	176	32	the	the	DT
cord-293938-40zyv1h8	176	33	host	host	NN
cord-293938-40zyv1h8	176	34	immune	immune	JJ
cord-293938-40zyv1h8	176	35	system	system	NN
cord-293938-40zyv1h8	176	36	as	as	RB
cord-293938-40zyv1h8	176	37	well	well	RB
cord-293938-40zyv1h8	176	38	as	as	IN
cord-293938-40zyv1h8	176	39	identifying	identify	VBG
cord-293938-40zyv1h8	176	40	antiviral	antiviral	JJ
cord-293938-40zyv1h8	176	41	compounds	compound	NNS
cord-293938-40zyv1h8	176	42	and	and	CC
cord-293938-40zyv1h8	176	43	human	human	JJ
cord-293938-40zyv1h8	176	44	vaccine	vaccine	NN
cord-293938-40zyv1h8	176	45	candidates	candidate	NNS
cord-293938-40zyv1h8	176	46	.	.	.
cord-293938-40zyv1h8	177	1	The	the	DT
cord-293938-40zyv1h8	177	2	HAE	HAE	NNP
cord-293938-40zyv1h8	177	3	culture	culture	NN
cord-293938-40zyv1h8	177	4	system	system	NN
cord-293938-40zyv1h8	177	5	is	be	VBZ
cord-293938-40zyv1h8	177	6	based	base	VBN
cord-293938-40zyv1h8	177	7	on	on	IN
cord-293938-40zyv1h8	177	8	primary	primary	JJ
cord-293938-40zyv1h8	177	9	human	human	JJ
cord-293938-40zyv1h8	177	10	cells	cell	NNS
cord-293938-40zyv1h8	177	11	offering	offer	VBG
cord-293938-40zyv1h8	177	12	a	a	DT
cord-293938-40zyv1h8	177	13	unique	unique	JJ
cord-293938-40zyv1h8	177	14	platform	platform	NN
cord-293938-40zyv1h8	177	15	to	to	TO
cord-293938-40zyv1h8	177	16	study	study	VB
cord-293938-40zyv1h8	177	17	respiratory	respiratory	JJ
cord-293938-40zyv1h8	177	18	viruses	virus	NNS
cord-293938-40zyv1h8	177	19	in	in	IN
cord-293938-40zyv1h8	177	20	cells	cell	NNS
cord-293938-40zyv1h8	177	21	representing	represent	VBG
cord-293938-40zyv1h8	177	22	the	the	DT
cord-293938-40zyv1h8	177	23	primary	primary	JJ
cord-293938-40zyv1h8	177	24	entry	entry	NN
cord-293938-40zyv1h8	177	25	point	point	NN
cord-293938-40zyv1h8	177	26	of	of	IN
cord-293938-40zyv1h8	177	27	these	these	DT
cord-293938-40zyv1h8	177	28	viruses	virus	NNS
cord-293938-40zyv1h8	177	29	,	,	,
cord-293938-40zyv1h8	177	30	bronchial	bronchial	JJ
cord-293938-40zyv1h8	177	31	epithelial	epithelial	JJ
cord-293938-40zyv1h8	177	32	cells	cell	NNS
cord-293938-40zyv1h8	177	33	,	,	,
cord-293938-40zyv1h8	177	34	or	or	CC
cord-293938-40zyv1h8	177	35	investigate	investigate	VB
cord-293938-40zyv1h8	177	36	the	the	DT
cord-293938-40zyv1h8	177	37	interaction	interaction	NN
cord-293938-40zyv1h8	177	38	of	of	IN
cord-293938-40zyv1h8	177	39	HCoVs	HCoVs	NNP
cord-293938-40zyv1h8	177	40	and	and	CC
cord-293938-40zyv1h8	177	41	the	the	DT
cord-293938-40zyv1h8	177	42	distal	distal	JJ
cord-293938-40zyv1h8	177	43	airways	airways	NNPS
cord-293938-40zyv1h8	177	44	,	,	,
cord-293938-40zyv1h8	177	45	in	in	IN
cord-293938-40zyv1h8	177	46	type	type	NN
cord-293938-40zyv1h8	177	47	I	-PRON-	PRP
cord-293938-40zyv1h8	177	48	and	and	CC
cord-293938-40zyv1h8	177	49	II	ii	CD
cord-293938-40zyv1h8	177	50	alveolar	alveolar	NN
cord-293938-40zyv1h8	177	51	cells	cell	NNS
cord-293938-40zyv1h8	177	52	.	.	.
cord-293938-40zyv1h8	178	1	Additionally	additionally	RB
cord-293938-40zyv1h8	178	2	,	,	,
cord-293938-40zyv1h8	178	3	the	the	DT
cord-293938-40zyv1h8	178	4	inclusion	inclusion	NN
cord-293938-40zyv1h8	178	5	of	of	IN
cord-293938-40zyv1h8	178	6	airway	airway	JJ
cord-293938-40zyv1h8	178	7	epithelial	epithelial	JJ
cord-293938-40zyv1h8	178	8	cultures	culture	NNS
cord-293938-40zyv1h8	178	9	for	for	IN
cord-293938-40zyv1h8	178	10	other	other	JJ
cord-293938-40zyv1h8	178	11	species	specie	NNS
cord-293938-40zyv1h8	178	12	enables	enable	VBZ
cord-293938-40zyv1h8	178	13	the	the	DT
cord-293938-40zyv1h8	178	14	study	study	NN
cord-293938-40zyv1h8	178	15	of	of	IN
cord-293938-40zyv1h8	178	16	zoonosis	zoonosis	NN
cord-293938-40zyv1h8	178	17	and	and	CC
cord-293938-40zyv1h8	178	18	animal	animal	NN
cord-293938-40zyv1h8	178	19	-	-	HYPH
cord-293938-40zyv1h8	178	20	to	to	IN
cord-293938-40zyv1h8	178	21	-	-	HYPH
cord-293938-40zyv1h8	178	22	human	human	JJ
cord-293938-40zyv1h8	178	23	transmission	transmission	NN
cord-293938-40zyv1h8	178	24	.	.	.
cord-293938-40zyv1h8	179	1	Currently	currently	RB
cord-293938-40zyv1h8	179	2	,	,	,
cord-293938-40zyv1h8	179	3	many	many	JJ
cord-293938-40zyv1h8	179	4	aspects	aspect	NNS
cord-293938-40zyv1h8	179	5	of	of	IN
cord-293938-40zyv1h8	179	6	HCoV	hcov	NN
cord-293938-40zyv1h8	179	7	infection	infection	NN
cord-293938-40zyv1h8	179	8	and	and	CC
cord-293938-40zyv1h8	179	9	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	179	10	remain	remain	VBP
cord-293938-40zyv1h8	179	11	to	to	TO
cord-293938-40zyv1h8	179	12	be	be	VB
cord-293938-40zyv1h8	179	13	determined	determine	VBN
cord-293938-40zyv1h8	179	14	.	.	.
cord-293938-40zyv1h8	180	1	The	the	DT
cord-293938-40zyv1h8	180	2	HAE	HAE	NNP
cord-293938-40zyv1h8	180	3	culture	culture	NN
cord-293938-40zyv1h8	180	4	system	system	NN
cord-293938-40zyv1h8	180	5	,	,	,
cord-293938-40zyv1h8	180	6	both	both	CC
cord-293938-40zyv1h8	180	7	tracheobronchial	tracheobronchial	JJ
cord-293938-40zyv1h8	180	8	and	and	CC
cord-293938-40zyv1h8	180	9	alveolar	alveolar	NN
cord-293938-40zyv1h8	180	10	,	,	,
cord-293938-40zyv1h8	180	11	represents	represent	VBZ
cord-293938-40zyv1h8	180	12	a	a	DT
cord-293938-40zyv1h8	180	13	unique	unique	JJ
cord-293938-40zyv1h8	180	14	platform	platform	NN
cord-293938-40zyv1h8	180	15	to	to	TO
cord-293938-40zyv1h8	180	16	study	study	VB
cord-293938-40zyv1h8	180	17	virus	virus	NN
cord-293938-40zyv1h8	180	18	-	-	HYPH
cord-293938-40zyv1h8	180	19	host	host	NN
cord-293938-40zyv1h8	180	20	interaction	interaction	NN
cord-293938-40zyv1h8	180	21	in	in	IN
cord-293938-40zyv1h8	180	22	natural	natural	JJ
cord-293938-40zyv1h8	180	23	target	target	NN
cord-293938-40zyv1h8	180	24	cells	cell	NNS
cord-293938-40zyv1h8	180	25	at	at	IN
cord-293938-40zyv1h8	180	26	the	the	DT
cord-293938-40zyv1h8	180	27	molecular	molecular	JJ
cord-293938-40zyv1h8	180	28	level	level	NN
cord-293938-40zyv1h8	180	29	.	.	.
cord-293938-40zyv1h8	181	1	These	these	DT
cord-293938-40zyv1h8	181	2	cultures	culture	NNS
cord-293938-40zyv1h8	181	3	are	be	VBP
cord-293938-40zyv1h8	181	4	becoming	become	VBG
cord-293938-40zyv1h8	181	5	more	more	RBR
cord-293938-40zyv1h8	181	6	common	common	JJ
cord-293938-40zyv1h8	181	7	and	and	CC
cord-293938-40zyv1h8	181	8	more	more	RBR
cord-293938-40zyv1h8	181	9	relevant	relevant	JJ
cord-293938-40zyv1h8	181	10	to	to	TO
cord-293938-40zyv1h8	181	11	HCoV	hcov	VB
cord-293938-40zyv1h8	181	12	research	research	NN
cord-293938-40zyv1h8	181	13	.	.	.
cord-293938-40zyv1h8	182	1	Especially	especially	RB
cord-293938-40zyv1h8	182	2	,	,	,
cord-293938-40zyv1h8	182	3	for	for	IN
cord-293938-40zyv1h8	182	4	those	those	DT
cord-293938-40zyv1h8	182	5	viruses	virus	NNS
cord-293938-40zyv1h8	182	6	for	for	IN
cord-293938-40zyv1h8	182	7	which	which	WDT
cord-293938-40zyv1h8	182	8	there	there	EX
cord-293938-40zyv1h8	182	9	is	be	VBZ
cord-293938-40zyv1h8	182	10	no	no	DT
cord-293938-40zyv1h8	182	11	animal	animal	NN
cord-293938-40zyv1h8	182	12	model	model	NN
cord-293938-40zyv1h8	182	13	,	,	,
cord-293938-40zyv1h8	182	14	as	as	IN
cord-293938-40zyv1h8	182	15	they	-PRON-	PRP
cord-293938-40zyv1h8	182	16	provide	provide	VBP
cord-293938-40zyv1h8	182	17	an	an	DT
cord-293938-40zyv1h8	182	18	organotypic	organotypic	JJ
cord-293938-40zyv1h8	182	19	substitute	substitute	NN
cord-293938-40zyv1h8	182	20	for	for	IN
cord-293938-40zyv1h8	182	21	virushost	virushost	NN
cord-293938-40zyv1h8	182	22	interaction	interaction	NN
cord-293938-40zyv1h8	182	23	studies	study	NNS
cord-293938-40zyv1h8	182	24	.	.	.
cord-293938-40zyv1h8	182	25	 	 	_SP
cord-293938-40zyv1h8	183	1	The	the	DT
cord-293938-40zyv1h8	183	2	authors	author	NNS
cord-293938-40zyv1h8	183	3	declare	declare	VBP
cord-293938-40zyv1h8	183	4	no	no	DT
cord-293938-40zyv1h8	183	5	competing	compete	VBG
cord-293938-40zyv1h8	183	6	interests	interest	NNS
cord-293938-40zyv1h8	183	7	.	.	.
cord-293938-40zyv1h8	184	1	Authors	author	NNS
cord-293938-40zyv1h8	184	2	'	'	POS
cord-293938-40zyv1h8	184	3	contribution	contribution	NN
cord-293938-40zyv1h8	184	4	HRJ	HRJ	NNP
cord-293938-40zyv1h8	184	5	wrote	write	VBD
cord-293938-40zyv1h8	184	6	the	the	DT
cord-293938-40zyv1h8	184	7	review	review	NN
cord-293938-40zyv1h8	184	8	,	,	,
cord-293938-40zyv1h8	184	9	designed	design	VBN
cord-293938-40zyv1h8	184	10	tables	table	NNS
cord-293938-40zyv1h8	184	11	and	and	CC
cord-293938-40zyv1h8	184	12	figures	figure	NNS
cord-293938-40zyv1h8	184	13	.	.	.
cord-293938-40zyv1h8	185	1	RD	RD	NNP
cord-293938-40zyv1h8	185	2	revised	revise	VBD
cord-293938-40zyv1h8	185	3	the	the	DT
cord-293938-40zyv1h8	185	4	text	text	NN
cord-293938-40zyv1h8	185	5	,	,	,
cord-293938-40zyv1h8	185	6	tables	table	NNS
cord-293938-40zyv1h8	185	7	and	and	CC
cord-293938-40zyv1h8	185	8	figures	figure	NNS
cord-293938-40zyv1h8	185	9	.	.	.
cord-293938-40zyv1h8	186	1	Both	both	DT
cord-293938-40zyv1h8	186	2	authors	author	NNS
cord-293938-40zyv1h8	186	3	read	read	VBP
cord-293938-40zyv1h8	186	4	and	and	CC
cord-293938-40zyv1h8	186	5	approved	approve	VBD
cord-293938-40zyv1h8	186	6	the	the	DT
cord-293938-40zyv1h8	186	7	final	final	JJ
cord-293938-40zyv1h8	186	8	manuscript	manuscript	NN
cord-293938-40zyv1h8	186	9	.	.	.
cord-293938-40zyv1h8	187	1	This	this	DT
cord-293938-40zyv1h8	187	2	work	work	NN
cord-293938-40zyv1h8	187	3	was	be	VBD
cord-293938-40zyv1h8	187	4	supported	support	VBN
cord-293938-40zyv1h8	187	5	by	by	IN
cord-293938-40zyv1h8	187	6	the	the	DT
cord-293938-40zyv1h8	187	7	3R	3R	NNP
cord-293938-40zyv1h8	187	8	Foundation	Foundation	NNP
cord-293938-40zyv1h8	187	9	,	,	,
cord-293938-40zyv1h8	187	10	Switzerland	Switzerland	NNP
cord-293938-40zyv1h8	187	11	(	(	-LRB-
cord-293938-40zyv1h8	187	12	project	project	NN
cord-293938-40zyv1h8	187	13	128	128	CD
cord-293938-40zyv1h8	187	14	-	-	SYM
cord-293938-40zyv1h8	187	15	11	11	CD
cord-293938-40zyv1h8	187	16	)	)	-RRB-
cord-293938-40zyv1h8	187	17	and	and	CC
cord-293938-40zyv1h8	187	18	the	the	DT
cord-293938-40zyv1h8	187	19	University	University	NNP
cord-293938-40zyv1h8	187	20	of	of	IN
cord-293938-40zyv1h8	187	21	Bern	Bern	NNP
cord-293938-40zyv1h8	187	22	Initiator	Initiator	NNP
cord-293938-40zyv1h8	187	23	Grant	Grant	NNP
cord-293938-40zyv1h8	187	24	.	.	.
cord-293938-40zyv1h8	188	1	Received	receive	VBN
cord-293938-40zyv1h8	188	2	:	:	:
cord-293938-40zyv1h8	188	3	17	17	CD
cord-293938-40zyv1h8	188	4	December	December	NNP
cord-293938-40zyv1h8	188	5	2015	2015	CD
cord-293938-40zyv1h8	189	1	Accepted	accept	VBN
cord-293938-40zyv1h8	189	2	:	:	:
cord-293938-40zyv1h8	190	1	27	27	CD
cord-293938-40zyv1h8	190	2	January	January	NNP
cord-293938-40zyv1h8	190	3	2016	2016	CD
cord-293938-40zyv1h8	190	4	Coronaviruses	Coronaviruses	NNPS
cord-293938-40zyv1h8	190	5	:	:	:
cord-293938-40zyv1h8	190	6	an	an	DT
cord-293938-40zyv1h8	190	7	overview	overview	NN
cord-293938-40zyv1h8	190	8	of	of	IN
cord-293938-40zyv1h8	190	9	their	-PRON-	PRP$
cord-293938-40zyv1h8	190	10	replication	replication	NN
cord-293938-40zyv1h8	190	11	and	and	CC
cord-293938-40zyv1h8	190	12	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	190	13	Coronavirus	Coronavirus	NNP
cord-293938-40zyv1h8	190	14	genome	genome	NN
cord-293938-40zyv1h8	190	15	structure	structure	NN
cord-293938-40zyv1h8	190	16	and	and	CC
cord-293938-40zyv1h8	190	17	replication	replication	NN
cord-293938-40zyv1h8	190	18	The	the	DT
cord-293938-40zyv1h8	190	19	Genome	Genome	NNP
cord-293938-40zyv1h8	190	20	Organization	Organization	NNP
cord-293938-40zyv1h8	190	21	of	of	IN
cord-293938-40zyv1h8	190	22	the	the	DT
cord-293938-40zyv1h8	190	23	Nidovirales	Nidovirales	NNPS
cord-293938-40zyv1h8	190	24	:	:	:
cord-293938-40zyv1h8	190	25	Similarities	similarity	NNS
cord-293938-40zyv1h8	190	26	and	and	CC
cord-293938-40zyv1h8	190	27	Differences	difference	NNS
cord-293938-40zyv1h8	190	28	between	between	IN
cord-293938-40zyv1h8	190	29	Arteri-	Arteri-	NNP
cord-293938-40zyv1h8	190	30	,	,	,
cord-293938-40zyv1h8	190	31	Toro-	Toro-	NNP
cord-293938-40zyv1h8	190	32	,	,	,
cord-293938-40zyv1h8	190	33	and	and	CC
cord-293938-40zyv1h8	190	34	Coronaviruses	Coronaviruses	NNP
cord-293938-40zyv1h8	190	35	A	a	DT
cord-293938-40zyv1h8	190	36	new	new	JJ
cord-293938-40zyv1h8	190	37	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	190	38	-	-	HYPH
cord-293938-40zyv1h8	190	39	like	like	JJ
cord-293938-40zyv1h8	190	40	particle	particle	NN
cord-293938-40zyv1h8	190	41	associated	associate	VBN
cord-293938-40zyv1h8	190	42	with	with	IN
cord-293938-40zyv1h8	190	43	diarrhea	diarrhea	NN
cord-293938-40zyv1h8	190	44	in	in	IN
cord-293938-40zyv1h8	190	45	swine	swine	NN
cord-293938-40zyv1h8	190	46	A	a	DT
cord-293938-40zyv1h8	190	47	nomenclature	nomenclature	NN
cord-293938-40zyv1h8	190	48	for	for	IN
cord-293938-40zyv1h8	190	49	avian	avian	JJ
cord-293938-40zyv1h8	190	50	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	190	51	isolates	isolate	NNS
cord-293938-40zyv1h8	190	52	and	and	CC
cord-293938-40zyv1h8	190	53	the	the	DT
cord-293938-40zyv1h8	190	54	question	question	NN
cord-293938-40zyv1h8	190	55	of	of	IN
cord-293938-40zyv1h8	190	56	species	species	NN
cord-293938-40zyv1h8	190	57	status	status	NN
cord-293938-40zyv1h8	190	58	Enteric	enteric	JJ
cord-293938-40zyv1h8	190	59	disease	disease	NN
cord-293938-40zyv1h8	190	60	in	in	IN
cord-293938-40zyv1h8	190	61	postweaned	postweaned	JJ
cord-293938-40zyv1h8	190	62	beef	beef	NN
cord-293938-40zyv1h8	190	63	calves	calf	NNS
cord-293938-40zyv1h8	190	64	associated	associate	VBN
cord-293938-40zyv1h8	190	65	with	with	IN
cord-293938-40zyv1h8	190	66	Bovine	bovine	JJ
cord-293938-40zyv1h8	190	67	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	190	68	clade	clade	NN
cord-293938-40zyv1h8	190	69	2	2	CD
cord-293938-40zyv1h8	190	70	Cleavage	cleavage	NN
cord-293938-40zyv1h8	190	71	of	of	IN
cord-293938-40zyv1h8	190	72	a	a	DT
cord-293938-40zyv1h8	190	73	Neuroinvasive	Neuroinvasive	NNP
cord-293938-40zyv1h8	190	74	Human	Human	NNP
cord-293938-40zyv1h8	190	75	Respiratory	Respiratory	NNP
cord-293938-40zyv1h8	190	76	Virus	virus	NN
cord-293938-40zyv1h8	190	77	Spike	spike	NN
cord-293938-40zyv1h8	190	78	Glycoprotein	Glycoprotein	NNP
cord-293938-40zyv1h8	190	79	by	by	IN
cord-293938-40zyv1h8	190	80	Proprotein	Proprotein	NNP
cord-293938-40zyv1h8	190	81	Convertases	Convertases	NNP
cord-293938-40zyv1h8	190	82	Modulates	modulate	VBZ
cord-293938-40zyv1h8	191	1	Neurovirulence	Neurovirulence	NNP
cord-293938-40zyv1h8	191	2	and	and	CC
cord-293938-40zyv1h8	191	3	Virus	Virus	NNP
cord-293938-40zyv1h8	191	4	Spread	Spread	VBD
cord-293938-40zyv1h8	191	5	within	within	IN
cord-293938-40zyv1h8	191	6	the	the	DT
cord-293938-40zyv1h8	191	7	Central	Central	NNP
cord-293938-40zyv1h8	191	8	Nervous	Nervous	NNP
cord-293938-40zyv1h8	191	9	System	System	NNP
cord-293938-40zyv1h8	192	1	The	the	DT
cord-293938-40zyv1h8	192	2	chemokine	chemokine	NN
cord-293938-40zyv1h8	192	3	receptor	receptor	NN
cord-293938-40zyv1h8	192	4	CXCR2	CXCR2	NNS
cord-293938-40zyv1h8	192	5	and	and	CC
cord-293938-40zyv1h8	192	6	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	192	7	-	-	HYPH
cord-293938-40zyv1h8	192	8	induced	induce	VBN
cord-293938-40zyv1h8	192	9	neurologic	neurologic	JJ
cord-293938-40zyv1h8	192	10	disease	disease	NN
cord-293938-40zyv1h8	192	11	Acute	acute	JJ
cord-293938-40zyv1h8	192	12	hepatic	hepatic	JJ
cord-293938-40zyv1h8	192	13	failure	failure	NN
cord-293938-40zyv1h8	192	14	in	in	IN
cord-293938-40zyv1h8	192	15	IFN	IFN	NNP
cord-293938-40zyv1h8	192	16	-	-	HYPH
cord-293938-40zyv1h8	192	17	gamma	gamma	NN
cord-293938-40zyv1h8	192	18	-	-	HYPH
cord-293938-40zyv1h8	192	19	deficient	deficient	JJ
cord-293938-40zyv1h8	192	20	BALB	BALB	NNP
cord-293938-40zyv1h8	192	21	/	/	SYM
cord-293938-40zyv1h8	192	22	c	c	NN
cord-293938-40zyv1h8	192	23	mice	mouse	NNS
cord-293938-40zyv1h8	193	1	after	after	IN
cord-293938-40zyv1h8	193	2	murine	murine	JJ
cord-293938-40zyv1h8	193	3	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	193	4	infection	infection	NN
cord-293938-40zyv1h8	193	5	Detection	detection	NN
cord-293938-40zyv1h8	193	6	of	of	IN
cord-293938-40zyv1h8	193	7	feline	feline	JJ
cord-293938-40zyv1h8	193	8	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	193	9	spike	spike	NN
cord-293938-40zyv1h8	193	10	gene	gene	NN
cord-293938-40zyv1h8	193	11	mutations	mutation	NNS
cord-293938-40zyv1h8	193	12	as	as	IN
cord-293938-40zyv1h8	193	13	a	a	DT
cord-293938-40zyv1h8	193	14	tool	tool	NN
cord-293938-40zyv1h8	193	15	to	to	TO
cord-293938-40zyv1h8	193	16	diagnose	diagnose	VB
cord-293938-40zyv1h8	193	17	feline	feline	JJ
cord-293938-40zyv1h8	193	18	infectious	infectious	JJ
cord-293938-40zyv1h8	193	19	peritonitis	peritonitis	NN
cord-293938-40zyv1h8	193	20	A	a	DT
cord-293938-40zyv1h8	193	21	new	new	JJ
cord-293938-40zyv1h8	193	22	virus	virus	NN
cord-293938-40zyv1h8	193	23	isolated	isolate	VBN
cord-293938-40zyv1h8	193	24	from	from	IN
cord-293938-40zyv1h8	193	25	the	the	DT
cord-293938-40zyv1h8	193	26	human	human	JJ
cord-293938-40zyv1h8	193	27	respiratory	respiratory	JJ
cord-293938-40zyv1h8	193	28	tract	tract	NN
cord-293938-40zyv1h8	193	29	Recovery	recovery	NN
cord-293938-40zyv1h8	193	30	in	in	IN
cord-293938-40zyv1h8	193	31	tracheal	tracheal	JJ
cord-293938-40zyv1h8	193	32	organ	organ	NN
cord-293938-40zyv1h8	193	33	cultures	culture	NNS
cord-293938-40zyv1h8	193	34	of	of	IN
cord-293938-40zyv1h8	193	35	novel	novel	NN
cord-293938-40zyv1h8	193	36	viruses	virus	NNS
cord-293938-40zyv1h8	193	37	from	from	IN
cord-293938-40zyv1h8	193	38	patients	patient	NNS
cord-293938-40zyv1h8	193	39	with	with	IN
cord-293938-40zyv1h8	193	40	respiratory	respiratory	JJ
cord-293938-40zyv1h8	193	41	disease	disease	NN
cord-293938-40zyv1h8	193	42	Identification	identification	NN
cord-293938-40zyv1h8	193	43	of	of	IN
cord-293938-40zyv1h8	193	44	a	a	DT
cord-293938-40zyv1h8	193	45	novel	novel	JJ
cord-293938-40zyv1h8	193	46	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	193	47	in	in	IN
cord-293938-40zyv1h8	193	48	patients	patient	NNS
cord-293938-40zyv1h8	193	49	with	with	IN
cord-293938-40zyv1h8	193	50	severe	severe	JJ
cord-293938-40zyv1h8	193	51	acute	acute	JJ
cord-293938-40zyv1h8	193	52	respiratory	respiratory	JJ
cord-293938-40zyv1h8	193	53	syndrome	syndrome	NN
cord-293938-40zyv1h8	193	54	Characterization	characterization	NN
cord-293938-40zyv1h8	193	55	of	of	IN
cord-293938-40zyv1h8	193	56	a	a	DT
cord-293938-40zyv1h8	193	57	novel	novel	JJ
cord-293938-40zyv1h8	193	58	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	193	59	associated	associate	VBN
cord-293938-40zyv1h8	193	60	with	with	IN
cord-293938-40zyv1h8	193	61	severe	severe	JJ
cord-293938-40zyv1h8	193	62	acute	acute	JJ
cord-293938-40zyv1h8	193	63	respiratory	respiratory	JJ
cord-293938-40zyv1h8	193	64	syndrome	syndrome	NN
cord-293938-40zyv1h8	193	65	Summary	summary	NN
cord-293938-40zyv1h8	193	66	of	of	IN
cord-293938-40zyv1h8	193	67	probable	probable	JJ
cord-293938-40zyv1h8	193	68	SARS	SARS	NNP
cord-293938-40zyv1h8	193	69	cases	case	NNS
cord-293938-40zyv1h8	193	70	with	with	IN
cord-293938-40zyv1h8	193	71	onset	onset	NN
cord-293938-40zyv1h8	193	72	of	of	IN
cord-293938-40zyv1h8	193	73	illness	illness	NN
cord-293938-40zyv1h8	193	74	from	from	IN
cord-293938-40zyv1h8	193	75	1	1	CD
cord-293938-40zyv1h8	193	76	Identification	Identification	NNP
cord-293938-40zyv1h8	193	77	of	of	IN
cord-293938-40zyv1h8	193	78	a	a	DT
cord-293938-40zyv1h8	193	79	new	new	JJ
cord-293938-40zyv1h8	193	80	human	human	JJ
cord-293938-40zyv1h8	193	81	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	193	82	Characterization	characterization	NN
cord-293938-40zyv1h8	193	83	and	and	CC
cord-293938-40zyv1h8	193	84	complete	complete	JJ
cord-293938-40zyv1h8	193	85	genome	genome	NN
cord-293938-40zyv1h8	193	86	sequence	sequence	NN
cord-293938-40zyv1h8	193	87	of	of	IN
cord-293938-40zyv1h8	193	88	a	a	DT
cord-293938-40zyv1h8	193	89	novel	novel	JJ
cord-293938-40zyv1h8	193	90	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	193	91	,	,	,
cord-293938-40zyv1h8	193	92	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	193	93	HKU1	HKU1	NNP
cord-293938-40zyv1h8	193	94	,	,	,
cord-293938-40zyv1h8	193	95	from	from	IN
cord-293938-40zyv1h8	193	96	patients	patient	NNS
cord-293938-40zyv1h8	193	97	with	with	IN
cord-293938-40zyv1h8	193	98	pneumonia	pneumonia	NN
cord-293938-40zyv1h8	193	99	Isolation	isolation	NN
cord-293938-40zyv1h8	193	100	of	of	IN
cord-293938-40zyv1h8	193	101	a	a	DT
cord-293938-40zyv1h8	193	102	novel	novel	JJ
cord-293938-40zyv1h8	193	103	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	193	104	from	from	IN
cord-293938-40zyv1h8	193	105	a	a	DT
cord-293938-40zyv1h8	193	106	man	man	NN
cord-293938-40zyv1h8	193	107	with	with	IN
cord-293938-40zyv1h8	193	108	pneumonia	pneumonia	NN
cord-293938-40zyv1h8	193	109	in	in	IN
cord-293938-40zyv1h8	193	110	Saudi	Saudi	NNP
cord-293938-40zyv1h8	193	111	Arabia	Arabia	NNP
cord-293938-40zyv1h8	193	112	Middle	Middle	NNP
cord-293938-40zyv1h8	193	113	East	East	NNP
cord-293938-40zyv1h8	193	114	Respiratory	Respiratory	NNP
cord-293938-40zyv1h8	193	115	Syndrome	Syndrome	NNP
cord-293938-40zyv1h8	193	116	Coronavirus	Coronavirus	NNP
cord-293938-40zyv1h8	193	117	Outbreak	outbreak	NN
cord-293938-40zyv1h8	193	118	in	in	IN
cord-293938-40zyv1h8	193	119	the	the	DT
cord-293938-40zyv1h8	193	120	Republic	Republic	NNP
cord-293938-40zyv1h8	193	121	of	of	IN
cord-293938-40zyv1h8	193	122	Korea	Korea	NNP
cord-293938-40zyv1h8	193	123	Effects	Effects	NNPS
cord-293938-40zyv1h8	193	124	of	of	IN
cord-293938-40zyv1h8	193	125	a	a	DT
cord-293938-40zyv1h8	193	126	"	"	``
cord-293938-40zyv1h8	193	127	new	new	JJ
cord-293938-40zyv1h8	193	128	"	"	''
cord-293938-40zyv1h8	193	129	human	human	JJ
cord-293938-40zyv1h8	193	130	respiratory	respiratory	JJ
cord-293938-40zyv1h8	193	131	virus	virus	NN
cord-293938-40zyv1h8	193	132	in	in	IN
cord-293938-40zyv1h8	193	133	volunteers	volunteer	NNS
cord-293938-40zyv1h8	193	134	Enzyme	Enzyme	NNP
cord-293938-40zyv1h8	193	135	-	-	HYPH
cord-293938-40zyv1h8	193	136	linked	link	VBN
cord-293938-40zyv1h8	193	137	immunosorbent	immunosorbent	JJ
cord-293938-40zyv1h8	193	138	assay	assay	NN
cord-293938-40zyv1h8	193	139	for	for	IN
cord-293938-40zyv1h8	193	140	detection	detection	NN
cord-293938-40zyv1h8	193	141	of	of	IN
cord-293938-40zyv1h8	193	142	antibody	antibody	NN
cord-293938-40zyv1h8	193	143	in	in	IN
cord-293938-40zyv1h8	193	144	volunteers	volunteer	NNS
cord-293938-40zyv1h8	193	145	experimentally	experimentally	RB
cord-293938-40zyv1h8	193	146	infected	infect	VBN
cord-293938-40zyv1h8	193	147	with	with	IN
cord-293938-40zyv1h8	193	148	human	human	JJ
cord-293938-40zyv1h8	193	149	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	193	150	strain	strain	VB
cord-293938-40zyv1h8	193	151	229	229	CD
cord-293938-40zyv1h8	193	152	E	e	NN
cord-293938-40zyv1h8	194	1	The	the	DT
cord-293938-40zyv1h8	194	2	behaviour	behaviour	NN
cord-293938-40zyv1h8	194	3	of	of	IN
cord-293938-40zyv1h8	194	4	recent	recent	JJ
cord-293938-40zyv1h8	194	5	isolates	isolate	NNS
cord-293938-40zyv1h8	194	6	of	of	IN
cord-293938-40zyv1h8	194	7	human	human	JJ
cord-293938-40zyv1h8	194	8	respiratory	respiratory	JJ
cord-293938-40zyv1h8	194	9	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	194	10	in	in	IN
cord-293938-40zyv1h8	194	11	vitro	vitro	FW
cord-293938-40zyv1h8	194	12	and	and	CC
cord-293938-40zyv1h8	194	13	in	in	IN
cord-293938-40zyv1h8	194	14	volunteers	volunteer	NNS
cord-293938-40zyv1h8	194	15	:	:	:
cord-293938-40zyv1h8	194	16	evidence	evidence	NN
cord-293938-40zyv1h8	194	17	of	of	IN
cord-293938-40zyv1h8	194	18	heterogeneity	heterogeneity	NN
cord-293938-40zyv1h8	194	19	among	among	IN
cord-293938-40zyv1h8	194	20	229E	229e	CD
cord-293938-40zyv1h8	194	21	-	-	HYPH
cord-293938-40zyv1h8	194	22	related	relate	VBN
cord-293938-40zyv1h8	194	23	strains	strain	NNS
cord-293938-40zyv1h8	195	1	The	the	DT
cord-293938-40zyv1h8	195	2	"	"	``
cord-293938-40zyv1h8	195	3	common	common	JJ
cord-293938-40zyv1h8	195	4	cold	cold	NN
cord-293938-40zyv1h8	195	5	"	"	''
cord-293938-40zyv1h8	195	6	in	in	IN
cord-293938-40zyv1h8	195	7	frail	frail	JJ
cord-293938-40zyv1h8	195	8	older	old	JJR
cord-293938-40zyv1h8	195	9	persons	person	NNS
cord-293938-40zyv1h8	195	10	:	:	:
cord-293938-40zyv1h8	195	11	impact	impact	NN
cord-293938-40zyv1h8	195	12	of	of	IN
cord-293938-40zyv1h8	195	13	rhinovirus	rhinovirus	NN
cord-293938-40zyv1h8	195	14	and	and	CC
cord-293938-40zyv1h8	195	15	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	195	16	in	in	IN
cord-293938-40zyv1h8	195	17	a	a	DT
cord-293938-40zyv1h8	195	18	senior	senior	JJ
cord-293938-40zyv1h8	195	19	daycare	daycare	NN
cord-293938-40zyv1h8	195	20	center	center	NN
cord-293938-40zyv1h8	195	21	Human	Human	NNP
cord-293938-40zyv1h8	195	22	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	195	23	229E	229e	CD
cord-293938-40zyv1h8	195	24	infects	infect	VBZ
cord-293938-40zyv1h8	195	25	polarized	polarized	JJ
cord-293938-40zyv1h8	195	26	airway	airway	NN
cord-293938-40zyv1h8	195	27	epithelia	epithelium	NNS
cord-293938-40zyv1h8	195	28	from	from	IN
cord-293938-40zyv1h8	195	29	the	the	DT
cord-293938-40zyv1h8	195	30	apical	apical	JJ
cord-293938-40zyv1h8	195	31	surface	surface	NN
cord-293938-40zyv1h8	195	32	Culturing	culture	VBG
cord-293938-40zyv1h8	195	33	the	the	DT
cord-293938-40zyv1h8	195	34	unculturable	unculturable	JJ
cord-293938-40zyv1h8	195	35	:	:	:
cord-293938-40zyv1h8	195	36	human	human	JJ
cord-293938-40zyv1h8	195	37	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	195	38	HKU1	hku1	CD
cord-293938-40zyv1h8	195	39	infects	infect	VBZ
cord-293938-40zyv1h8	195	40	,	,	,
cord-293938-40zyv1h8	195	41	replicates	replicate	VBZ
cord-293938-40zyv1h8	195	42	,	,	,
cord-293938-40zyv1h8	195	43	and	and	CC
cord-293938-40zyv1h8	195	44	produces	produce	VBZ
cord-293938-40zyv1h8	195	45	progeny	progeny	JJ
cord-293938-40zyv1h8	195	46	virions	virion	NNS
cord-293938-40zyv1h8	195	47	in	in	IN
cord-293938-40zyv1h8	195	48	human	human	JJ
cord-293938-40zyv1h8	195	49	ciliated	ciliated	JJ
cord-293938-40zyv1h8	195	50	airway	airway	NN
cord-293938-40zyv1h8	195	51	epithelial	epithelial	JJ
cord-293938-40zyv1h8	195	52	cell	cell	NN
cord-293938-40zyv1h8	195	53	cultures	culture	NNS
cord-293938-40zyv1h8	195	54	Human	Human	NNP
cord-293938-40zyv1h8	195	55	Coronavirus	Coronavirus	NNP
cord-293938-40zyv1h8	195	56	-	-	HYPH
cord-293938-40zyv1h8	195	57	Associated	Associated	NNP
cord-293938-40zyv1h8	195	58	Influenza	Influenza	NNP
cord-293938-40zyv1h8	195	59	-	-	HYPH
cord-293938-40zyv1h8	195	60	Like	Like	NNP
cord-293938-40zyv1h8	195	61	Illness	Illness	NNP
cord-293938-40zyv1h8	195	62	in	in	IN
cord-293938-40zyv1h8	195	63	the	the	DT
cord-293938-40zyv1h8	195	64	Community	Community	NNP
cord-293938-40zyv1h8	195	65	Setting	set	VBG
cord-293938-40zyv1h8	195	66	in	in	IN
cord-293938-40zyv1h8	195	67	Peru	Peru	NNP
cord-293938-40zyv1h8	195	68	High	high	JJ
cord-293938-40zyv1h8	195	69	incidence	incidence	NN
cord-293938-40zyv1h8	195	70	but	but	CC
cord-293938-40zyv1h8	195	71	low	low	JJ
cord-293938-40zyv1h8	195	72	burden	burden	NN
cord-293938-40zyv1h8	195	73	of	of	IN
cord-293938-40zyv1h8	195	74	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	195	75	and	and	CC
cord-293938-40zyv1h8	195	76	preferential	preferential	JJ
cord-293938-40zyv1h8	195	77	associations	association	NNS
cord-293938-40zyv1h8	195	78	between	between	IN
cord-293938-40zyv1h8	195	79	respiratory	respiratory	JJ
cord-293938-40zyv1h8	195	80	viruses	virus	NNS
cord-293938-40zyv1h8	196	1	The	the	DT
cord-293938-40zyv1h8	196	2	pediatric	pediatric	JJ
cord-293938-40zyv1h8	196	3	burden	burden	NN
cord-293938-40zyv1h8	196	4	of	of	IN
cord-293938-40zyv1h8	196	5	human	human	JJ
cord-293938-40zyv1h8	196	6	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	196	7	evaluated	evaluate	VBN
cord-293938-40zyv1h8	196	8	for	for	IN
cord-293938-40zyv1h8	196	9	twenty	twenty	CD
cord-293938-40zyv1h8	196	10	years	year	NNS
cord-293938-40zyv1h8	196	11	Ecology	ecology	NN
cord-293938-40zyv1h8	196	12	,	,	,
cord-293938-40zyv1h8	196	13	evolution	evolution	NN
cord-293938-40zyv1h8	196	14	and	and	CC
cord-293938-40zyv1h8	196	15	classification	classification	NN
cord-293938-40zyv1h8	196	16	of	of	IN
cord-293938-40zyv1h8	196	17	bat	bat	NN
cord-293938-40zyv1h8	196	18	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	196	19	in	in	IN
cord-293938-40zyv1h8	196	20	the	the	DT
cord-293938-40zyv1h8	196	21	aftermath	aftermath	NN
cord-293938-40zyv1h8	196	22	of	of	IN
cord-293938-40zyv1h8	196	23	SARS	SARS	NNP
cord-293938-40zyv1h8	196	24	Evidence	Evidence	NNP
cord-293938-40zyv1h8	196	25	supporting	support	VBG
cord-293938-40zyv1h8	196	26	a	a	DT
cord-293938-40zyv1h8	196	27	zoonotic	zoonotic	JJ
cord-293938-40zyv1h8	196	28	origin	origin	NN
cord-293938-40zyv1h8	196	29	of	of	IN
cord-293938-40zyv1h8	196	30	human	human	JJ
cord-293938-40zyv1h8	196	31	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	196	32	strain	strain	VBP
cord-293938-40zyv1h8	196	33	NL63	NL63	NNP
cord-293938-40zyv1h8	196	34	Evidence	evidence	NN
cord-293938-40zyv1h8	196	35	for	for	IN
cord-293938-40zyv1h8	196	36	an	an	DT
cord-293938-40zyv1h8	196	37	Ancestral	Ancestral	NNP
cord-293938-40zyv1h8	196	38	Association	Association	NNP
cord-293938-40zyv1h8	196	39	of	of	IN
cord-293938-40zyv1h8	196	40	Human	Human	NNP
cord-293938-40zyv1h8	196	41	Coronavirus	Coronavirus	NNP
cord-293938-40zyv1h8	196	42	229E	229e	CD
cord-293938-40zyv1h8	196	43	with	with	IN
cord-293938-40zyv1h8	196	44	Bats	bat	NNS
cord-293938-40zyv1h8	196	45	Estimating	estimate	VBG
cord-293938-40zyv1h8	196	46	the	the	DT
cord-293938-40zyv1h8	196	47	risk	risk	NN
cord-293938-40zyv1h8	196	48	of	of	IN
cord-293938-40zyv1h8	196	49	Middle	Middle	NNP
cord-293938-40zyv1h8	196	50	East	East	NNP
cord-293938-40zyv1h8	196	51	respiratory	respiratory	JJ
cord-293938-40zyv1h8	196	52	syndrome	syndrome	NN
cord-293938-40zyv1h8	196	53	(	(	-LRB-
cord-293938-40zyv1h8	196	54	MERS	MERS	NNP
cord-293938-40zyv1h8	196	55	)	)	-RRB-
cord-293938-40zyv1h8	196	56	death	death	NN
cord-293938-40zyv1h8	196	57	during	during	IN
cord-293938-40zyv1h8	196	58	the	the	DT
cord-293938-40zyv1h8	196	59	course	course	NN
cord-293938-40zyv1h8	196	60	of	of	IN
cord-293938-40zyv1h8	196	61	the	the	DT
cord-293938-40zyv1h8	196	62	outbreak	outbreak	NN
cord-293938-40zyv1h8	196	63	in	in	IN
cord-293938-40zyv1h8	196	64	the	the	DT
cord-293938-40zyv1h8	196	65	Republic	Republic	NNP
cord-293938-40zyv1h8	196	66	of	of	IN
cord-293938-40zyv1h8	196	67	Korea	Korea	NNP
cord-293938-40zyv1h8	197	1	The	the	DT
cord-293938-40zyv1h8	197	2	emergence	emergence	NN
cord-293938-40zyv1h8	197	3	of	of	IN
cord-293938-40zyv1h8	197	4	the	the	DT
cord-293938-40zyv1h8	197	5	Middle	Middle	NNP
cord-293938-40zyv1h8	197	6	East	East	NNP
cord-293938-40zyv1h8	197	7	Respiratory	Respiratory	NNP
cord-293938-40zyv1h8	197	8	Syndrome	Syndrome	NNP
cord-293938-40zyv1h8	197	9	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	197	10	(	(	-LRB-
cord-293938-40zyv1h8	197	11	MERS	MERS	NNP
cord-293938-40zyv1h8	197	12	-	-	HYPH
cord-293938-40zyv1h8	197	13	CoV	CoV	NNP
cord-293938-40zyv1h8	197	14	)	)	-RRB-
cord-293938-40zyv1h8	197	15	.	.	.
cord-293938-40zyv1h8	198	1	Pathogens	pathogen	NNS
cord-293938-40zyv1h8	198	2	and	and	CC
cord-293938-40zyv1h8	198	3	disease	disease	NN
cord-293938-40zyv1h8	198	4	ORF8-Related	orf8-relate	VBD
cord-293938-40zyv1h8	198	5	Genetic	genetic	JJ
cord-293938-40zyv1h8	198	6	Evidence	evidence	NN
cord-293938-40zyv1h8	198	7	for	for	IN
cord-293938-40zyv1h8	198	8	Chinese	chinese	JJ
cord-293938-40zyv1h8	198	9	Horseshoe	Horseshoe	NNP
cord-293938-40zyv1h8	198	10	Bats	Bats	NNPS
cord-293938-40zyv1h8	198	11	as	as	IN
cord-293938-40zyv1h8	198	12	the	the	DT
cord-293938-40zyv1h8	198	13	Source	source	NN
cord-293938-40zyv1h8	198	14	of	of	IN
cord-293938-40zyv1h8	198	15	Human	Human	NNP
cord-293938-40zyv1h8	198	16	Severe	Severe	NNP
cord-293938-40zyv1h8	198	17	Acute	acute	JJ
cord-293938-40zyv1h8	198	18	Respiratory	Respiratory	NNP
cord-293938-40zyv1h8	198	19	Syndrome	Syndrome	NNP
cord-293938-40zyv1h8	198	20	Coronavirus	Coronavirus	NNP
cord-293938-40zyv1h8	198	21	Identification	Identification	NNP
cord-293938-40zyv1h8	198	22	of	of	IN
cord-293938-40zyv1h8	198	23	diverse	diverse	JJ
cord-293938-40zyv1h8	198	24	alphacoronaviruses	alphacoronaviruse	NNS
cord-293938-40zyv1h8	198	25	and	and	CC
cord-293938-40zyv1h8	198	26	genomic	genomic	JJ
cord-293938-40zyv1h8	198	27	characterization	characterization	NN
cord-293938-40zyv1h8	198	28	of	of	IN
cord-293938-40zyv1h8	198	29	a	a	DT
cord-293938-40zyv1h8	198	30	novel	novel	JJ
cord-293938-40zyv1h8	198	31	severe	severe	JJ
cord-293938-40zyv1h8	198	32	acute	acute	JJ
cord-293938-40zyv1h8	198	33	respiratory	respiratory	JJ
cord-293938-40zyv1h8	198	34	syndrome	syndrome	NN
cord-293938-40zyv1h8	198	35	-	-	HYPH
cord-293938-40zyv1h8	198	36	like	like	JJ
cord-293938-40zyv1h8	198	37	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	198	38	from	from	IN
cord-293938-40zyv1h8	198	39	bats	bat	NNS
cord-293938-40zyv1h8	198	40	in	in	IN
cord-293938-40zyv1h8	198	41	China	China	NNP
cord-293938-40zyv1h8	198	42	Novel	Novel	NNP
cord-293938-40zyv1h8	198	43	SARS	SARS	NNP
cord-293938-40zyv1h8	198	44	-	-	HYPH
cord-293938-40zyv1h8	198	45	like	like	JJ
cord-293938-40zyv1h8	198	46	betacoronaviruses	betacoronaviruse	NNS
cord-293938-40zyv1h8	198	47	in	in	IN
cord-293938-40zyv1h8	198	48	bats	bat	NNS
cord-293938-40zyv1h8	198	49	,	,	,
cord-293938-40zyv1h8	198	50	China	China	NNP
cord-293938-40zyv1h8	198	51	Isolation	Isolation	NNP
cord-293938-40zyv1h8	198	52	and	and	CC
cord-293938-40zyv1h8	198	53	characterization	characterization	NN
cord-293938-40zyv1h8	198	54	of	of	IN
cord-293938-40zyv1h8	198	55	a	a	DT
cord-293938-40zyv1h8	198	56	bat	bat	NN
cord-293938-40zyv1h8	198	57	SARS	SARS	NNP
cord-293938-40zyv1h8	198	58	-	-	HYPH
cord-293938-40zyv1h8	198	59	like	like	JJ
cord-293938-40zyv1h8	198	60	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	198	61	that	that	WDT
cord-293938-40zyv1h8	198	62	uses	use	VBZ
cord-293938-40zyv1h8	198	63	the	the	DT
cord-293938-40zyv1h8	198	64	ACE2	ACE2	NNP
cord-293938-40zyv1h8	198	65	receptor	receptor	NN
cord-293938-40zyv1h8	198	66	A	a	DT
cord-293938-40zyv1h8	198	67	SARS	SARS	NNP
cord-293938-40zyv1h8	198	68	-	-	HYPH
cord-293938-40zyv1h8	198	69	like	like	JJ
cord-293938-40zyv1h8	198	70	cluster	cluster	NN
cord-293938-40zyv1h8	198	71	of	of	IN
cord-293938-40zyv1h8	198	72	circulating	circulate	VBG
cord-293938-40zyv1h8	198	73	bat	bat	NN
cord-293938-40zyv1h8	198	74	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	198	75	shows	show	VBZ
cord-293938-40zyv1h8	198	76	potential	potential	NN
cord-293938-40zyv1h8	198	77	for	for	IN
cord-293938-40zyv1h8	198	78	human	human	JJ
cord-293938-40zyv1h8	198	79	emergence	emergence	NN
cord-293938-40zyv1h8	198	80	Rooting	root	VBG
cord-293938-40zyv1h8	198	81	the	the	DT
cord-293938-40zyv1h8	198	82	phylogenetic	phylogenetic	JJ
cord-293938-40zyv1h8	198	83	tree	tree	NN
cord-293938-40zyv1h8	198	84	of	of	IN
cord-293938-40zyv1h8	198	85	middle	middle	NNP
cord-293938-40zyv1h8	198	86	East	East	NNP
cord-293938-40zyv1h8	198	87	respiratory	respiratory	JJ
cord-293938-40zyv1h8	198	88	syndrome	syndrome	NN
cord-293938-40zyv1h8	198	89	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	198	90	by	by	IN
cord-293938-40zyv1h8	198	91	characterization	characterization	NN
cord-293938-40zyv1h8	198	92	of	of	IN
cord-293938-40zyv1h8	198	93	a	a	DT
cord-293938-40zyv1h8	198	94	conspecific	conspecific	JJ
cord-293938-40zyv1h8	198	95	virus	virus	NN
cord-293938-40zyv1h8	198	96	from	from	IN
cord-293938-40zyv1h8	198	97	an	an	DT
cord-293938-40zyv1h8	198	98	African	african	JJ
cord-293938-40zyv1h8	198	99	bat	bat	NN
cord-293938-40zyv1h8	198	100	Spread	spread	NN
cord-293938-40zyv1h8	198	101	,	,	,
cord-293938-40zyv1h8	198	102	circulation	circulation	NN
cord-293938-40zyv1h8	198	103	,	,	,
cord-293938-40zyv1h8	198	104	and	and	CC
cord-293938-40zyv1h8	198	105	evolution	evolution	NN
cord-293938-40zyv1h8	198	106	of	of	IN
cord-293938-40zyv1h8	198	107	the	the	DT
cord-293938-40zyv1h8	198	108	Middle	Middle	NNP
cord-293938-40zyv1h8	198	109	East	East	NNP
cord-293938-40zyv1h8	199	1	respiratory	respiratory	JJ
cord-293938-40zyv1h8	199	2	syndrome	syndrome	NN
cord-293938-40zyv1h8	199	3	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	199	4	Ready	ready	JJ
cord-293938-40zyv1h8	199	5	,	,	,
cord-293938-40zyv1h8	199	6	set	set	VBN
cord-293938-40zyv1h8	199	7	,	,	,
cord-293938-40zyv1h8	199	8	fuse	fuse	NN
cord-293938-40zyv1h8	199	9	!	!	.
cord-293938-40zyv1h8	200	1	The	the	DT
cord-293938-40zyv1h8	200	2	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	200	3	spike	spike	NN
cord-293938-40zyv1h8	200	4	protein	protein	NN
cord-293938-40zyv1h8	200	5	and	and	CC
cord-293938-40zyv1h8	200	6	acquisition	acquisition	NN
cord-293938-40zyv1h8	200	7	of	of	IN
cord-293938-40zyv1h8	200	8	fusion	fusion	NN
cord-293938-40zyv1h8	200	9	competence	competence	NN
cord-293938-40zyv1h8	200	10	Membrane	Membrane	NNP
cord-293938-40zyv1h8	200	11	ectopeptidases	ectopeptidase	NNS
cord-293938-40zyv1h8	200	12	targeted	target	VBN
cord-293938-40zyv1h8	200	13	by	by	IN
cord-293938-40zyv1h8	200	14	human	human	JJ
cord-293938-40zyv1h8	200	15	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	200	16	.	.	.
cord-293938-40zyv1h8	201	1	Current	current	JJ
cord-293938-40zyv1h8	201	2	Opinion	Opinion	NNP
cord-293938-40zyv1h8	201	3	in	in	IN
cord-293938-40zyv1h8	201	4	Virology	Virology	NNP
cord-293938-40zyv1h8	201	5	TMPRSS2	TMPRSS2	NNP
cord-293938-40zyv1h8	201	6	activates	activate	VBZ
cord-293938-40zyv1h8	201	7	the	the	DT
cord-293938-40zyv1h8	201	8	human	human	JJ
cord-293938-40zyv1h8	201	9	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	201	10	229E	229e	CD
cord-293938-40zyv1h8	201	11	for	for	IN
cord-293938-40zyv1h8	201	12	cathepsin	cathepsin	NN
cord-293938-40zyv1h8	201	13	-	-	HYPH
cord-293938-40zyv1h8	201	14	independent	independent	JJ
cord-293938-40zyv1h8	201	15	host	host	NN
cord-293938-40zyv1h8	201	16	cell	cell	NN
cord-293938-40zyv1h8	201	17	entry	entry	NN
cord-293938-40zyv1h8	201	18	and	and	CC
cord-293938-40zyv1h8	201	19	is	be	VBZ
cord-293938-40zyv1h8	201	20	expressed	express	VBN
cord-293938-40zyv1h8	201	21	in	in	IN
cord-293938-40zyv1h8	201	22	viral	viral	JJ
cord-293938-40zyv1h8	201	23	target	target	NN
cord-293938-40zyv1h8	201	24	cells	cell	NNS
cord-293938-40zyv1h8	201	25	in	in	IN
cord-293938-40zyv1h8	201	26	the	the	DT
cord-293938-40zyv1h8	201	27	respiratory	respiratory	JJ
cord-293938-40zyv1h8	201	28	epithelium	epithelium	NN
cord-293938-40zyv1h8	201	29	Evidence	evidence	NN
cord-293938-40zyv1h8	201	30	that	that	IN
cord-293938-40zyv1h8	201	31	TMPRSS2	TMPRSS2	NNP
cord-293938-40zyv1h8	201	32	activates	activate	VBZ
cord-293938-40zyv1h8	201	33	the	the	DT
cord-293938-40zyv1h8	201	34	severe	severe	JJ
cord-293938-40zyv1h8	201	35	acute	acute	JJ
cord-293938-40zyv1h8	201	36	respiratory	respiratory	JJ
cord-293938-40zyv1h8	201	37	syndrome	syndrome	NN
cord-293938-40zyv1h8	201	38	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	201	39	spike	spike	NN
cord-293938-40zyv1h8	201	40	protein	protein	NN
cord-293938-40zyv1h8	201	41	for	for	IN
cord-293938-40zyv1h8	201	42	membrane	membrane	NN
cord-293938-40zyv1h8	201	43	fusion	fusion	NN
cord-293938-40zyv1h8	201	44	and	and	CC
cord-293938-40zyv1h8	201	45	reduces	reduce	VBZ
cord-293938-40zyv1h8	201	46	viral	viral	JJ
cord-293938-40zyv1h8	201	47	control	control	NN
cord-293938-40zyv1h8	201	48	by	by	IN
cord-293938-40zyv1h8	201	49	the	the	DT
cord-293938-40zyv1h8	201	50	humoral	humoral	JJ
cord-293938-40zyv1h8	201	51	immune	immune	JJ
cord-293938-40zyv1h8	201	52	response	response	NN
cord-293938-40zyv1h8	202	1	Human	human	JJ
cord-293938-40zyv1h8	202	2	aminopeptidase	aminopeptidase	NN
cord-293938-40zyv1h8	202	3	N	N	NNP
cord-293938-40zyv1h8	202	4	is	be	VBZ
cord-293938-40zyv1h8	202	5	a	a	DT
cord-293938-40zyv1h8	202	6	receptor	receptor	NN
cord-293938-40zyv1h8	202	7	for	for	IN
cord-293938-40zyv1h8	202	8	human	human	JJ
cord-293938-40zyv1h8	202	9	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	202	10	229E	229e	CD
cord-293938-40zyv1h8	202	11	Expression	expression	NN
cord-293938-40zyv1h8	202	12	of	of	IN
cord-293938-40zyv1h8	202	13	aminopeptidase	aminopeptidase	NN
cord-293938-40zyv1h8	202	14	N	n	NN
cord-293938-40zyv1h8	202	15	and	and	CC
cord-293938-40zyv1h8	202	16	dipeptidyl	dipeptidyl	JJ
cord-293938-40zyv1h8	202	17	peptidase	peptidase	NN
cord-293938-40zyv1h8	202	18	IV	IV	NNP
cord-293938-40zyv1h8	202	19	in	in	IN
cord-293938-40zyv1h8	202	20	the	the	DT
cord-293938-40zyv1h8	202	21	healthy	healthy	JJ
cord-293938-40zyv1h8	202	22	and	and	CC
cord-293938-40zyv1h8	202	23	asthmatic	asthmatic	JJ
cord-293938-40zyv1h8	202	24	bronchus	bronchus	NN
cord-293938-40zyv1h8	202	25	Severe	severe	JJ
cord-293938-40zyv1h8	203	1	acute	acute	JJ
cord-293938-40zyv1h8	203	2	respiratory	respiratory	JJ
cord-293938-40zyv1h8	203	3	syndrome	syndrome	NN
cord-293938-40zyv1h8	203	4	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	203	5	infection	infection	NN
cord-293938-40zyv1h8	203	6	of	of	IN
cord-293938-40zyv1h8	203	7	mice	mouse	NNS
cord-293938-40zyv1h8	203	8	transgenic	transgenic	JJ
cord-293938-40zyv1h8	203	9	for	for	IN
cord-293938-40zyv1h8	203	10	the	the	DT
cord-293938-40zyv1h8	203	11	human	human	JJ
cord-293938-40zyv1h8	203	12	Angiotensin	Angiotensin	NNP
cord-293938-40zyv1h8	203	13	-	-	HYPH
cord-293938-40zyv1h8	203	14	converting	convert	VBG
cord-293938-40zyv1h8	203	15	enzyme	enzyme	NN
cord-293938-40zyv1h8	203	16	2	2	CD
cord-293938-40zyv1h8	203	17	virus	virus	NN
cord-293938-40zyv1h8	203	18	receptor	receptor	NN
cord-293938-40zyv1h8	203	19	Human	human	JJ
cord-293938-40zyv1h8	203	20	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	203	21	NL63	NL63	NNP
cord-293938-40zyv1h8	203	22	employs	employ	VBZ
cord-293938-40zyv1h8	203	23	the	the	DT
cord-293938-40zyv1h8	203	24	severe	severe	JJ
cord-293938-40zyv1h8	203	25	acute	acute	JJ
cord-293938-40zyv1h8	203	26	respiratory	respiratory	JJ
cord-293938-40zyv1h8	203	27	syndrome	syndrome	NN
cord-293938-40zyv1h8	203	28	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	203	29	receptor	receptor	NN
cord-293938-40zyv1h8	203	30	for	for	IN
cord-293938-40zyv1h8	203	31	cellular	cellular	JJ
cord-293938-40zyv1h8	203	32	entry	entry	NN
cord-293938-40zyv1h8	203	33	Tissue	tissue	NN
cord-293938-40zyv1h8	203	34	distribution	distribution	NN
cord-293938-40zyv1h8	203	35	of	of	IN
cord-293938-40zyv1h8	203	36	ACE2	ACE2	NNP
cord-293938-40zyv1h8	203	37	protein	protein	NN
cord-293938-40zyv1h8	203	38	,	,	,
cord-293938-40zyv1h8	203	39	the	the	DT
cord-293938-40zyv1h8	203	40	functional	functional	JJ
cord-293938-40zyv1h8	203	41	receptor	receptor	NN
cord-293938-40zyv1h8	203	42	for	for	IN
cord-293938-40zyv1h8	203	43	SARS	SARS	NNP
cord-293938-40zyv1h8	203	44	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	203	45	.	.	.
cord-293938-40zyv1h8	204	1	A	a	DT
cord-293938-40zyv1h8	204	2	first	first	JJ
cord-293938-40zyv1h8	204	3	step	step	NN
cord-293938-40zyv1h8	204	4	in	in	IN
cord-293938-40zyv1h8	204	5	understanding	understanding	NN
cord-293938-40zyv1h8	205	1	SARS	SARS	NNP
cord-293938-40zyv1h8	205	2	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	205	3	Dipeptidyl	Dipeptidyl	NNP
cord-293938-40zyv1h8	205	4	peptidase	peptidase	NN
cord-293938-40zyv1h8	205	5	4	4	CD
cord-293938-40zyv1h8	205	6	is	be	VBZ
cord-293938-40zyv1h8	205	7	a	a	DT
cord-293938-40zyv1h8	205	8	functional	functional	JJ
cord-293938-40zyv1h8	205	9	receptor	receptor	NN
cord-293938-40zyv1h8	205	10	for	for	IN
cord-293938-40zyv1h8	205	11	the	the	DT
cord-293938-40zyv1h8	205	12	emerging	emerge	VBG
cord-293938-40zyv1h8	205	13	human	human	JJ
cord-293938-40zyv1h8	205	14	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	205	15	-	-	HYPH
cord-293938-40zyv1h8	205	16	EMC	EMC	NNP
cord-293938-40zyv1h8	205	17	Dipeptidyl	Dipeptidyl	NNP
cord-293938-40zyv1h8	205	18	-	-	HYPH
cord-293938-40zyv1h8	205	19	peptidase	peptidase	NN
cord-293938-40zyv1h8	205	20	IV	IV	NNP
cord-293938-40zyv1h8	205	21	from	from	IN
cord-293938-40zyv1h8	205	22	bench	bench	NN
cord-293938-40zyv1h8	205	23	to	to	IN
cord-293938-40zyv1h8	205	24	bedside	bedside	NN
cord-293938-40zyv1h8	205	25	:	:	:
cord-293938-40zyv1h8	206	1	an	an	DT
cord-293938-40zyv1h8	206	2	update	update	NN
cord-293938-40zyv1h8	206	3	on	on	IN
cord-293938-40zyv1h8	206	4	structural	structural	JJ
cord-293938-40zyv1h8	206	5	properties	property	NNS
cord-293938-40zyv1h8	206	6	,	,	,
cord-293938-40zyv1h8	206	7	functions	function	NNS
cord-293938-40zyv1h8	206	8	,	,	,
cord-293938-40zyv1h8	206	9	and	and	CC
cord-293938-40zyv1h8	206	10	clinical	clinical	JJ
cord-293938-40zyv1h8	206	11	aspects	aspect	NNS
cord-293938-40zyv1h8	206	12	of	of	IN
cord-293938-40zyv1h8	206	13	the	the	DT
cord-293938-40zyv1h8	206	14	enzyme	enzyme	NN
cord-293938-40zyv1h8	206	15	DPP	DPP	NNP
cord-293938-40zyv1h8	206	16	IV	IV	NNP
cord-293938-40zyv1h8	206	17	Tropism	tropism	NN
cord-293938-40zyv1h8	206	18	of	of	IN
cord-293938-40zyv1h8	206	19	and	and	CC
cord-293938-40zyv1h8	206	20	innate	innate	JJ
cord-293938-40zyv1h8	206	21	immune	immune	JJ
cord-293938-40zyv1h8	206	22	responses	response	NNS
cord-293938-40zyv1h8	206	23	to	to	IN
cord-293938-40zyv1h8	206	24	the	the	DT
cord-293938-40zyv1h8	206	25	novel	novel	JJ
cord-293938-40zyv1h8	206	26	human	human	JJ
cord-293938-40zyv1h8	206	27	betacoronavirus	betacoronavirus	NN
cord-293938-40zyv1h8	206	28	lineage	lineage	NN
cord-293938-40zyv1h8	206	29	C	C	NNP
cord-293938-40zyv1h8	206	30	virus	virus	NN
cord-293938-40zyv1h8	206	31	in	in	IN
cord-293938-40zyv1h8	206	32	human	human	JJ
cord-293938-40zyv1h8	206	33	ex	ex	FW
cord-293938-40zyv1h8	206	34	vivo	vivo	NN
cord-293938-40zyv1h8	206	35	respiratory	respiratory	JJ
cord-293938-40zyv1h8	206	36	organ	organ	NN
cord-293938-40zyv1h8	206	37	cultures	culture	NNS
cord-293938-40zyv1h8	206	38	Human	Human	NNP
cord-293938-40zyv1h8	206	39	Coronavirus	Coronavirus	NNP
cord-293938-40zyv1h8	206	40	HKU1	HKU1	NNP
cord-293938-40zyv1h8	206	41	Spike	Spike	NNP
cord-293938-40zyv1h8	206	42	Protein	protein	NN
cord-293938-40zyv1h8	206	43	Uses	use	VBZ
cord-293938-40zyv1h8	206	44	O	O	NNP
cord-293938-40zyv1h8	206	45	-	-	HYPH
cord-293938-40zyv1h8	206	46	Acetylated	Acetylated	NNP
cord-293938-40zyv1h8	206	47	Sialic	Sialic	NNP
cord-293938-40zyv1h8	206	48	Acid	Acid	NNP
cord-293938-40zyv1h8	206	49	as	as	IN
cord-293938-40zyv1h8	206	50	an	an	DT
cord-293938-40zyv1h8	206	51	Attachment	Attachment	NNP
cord-293938-40zyv1h8	206	52	Receptor	Receptor	NNP
cord-293938-40zyv1h8	206	53	Determinant	Determinant	NNP
cord-293938-40zyv1h8	206	54	and	and	CC
cord-293938-40zyv1h8	206	55	Employs	employ	VBZ
cord-293938-40zyv1h8	206	56	Hemagglutinin	Hemagglutinin	NNP
cord-293938-40zyv1h8	206	57	-	-	HYPH
cord-293938-40zyv1h8	206	58	Esterase	Esterase	NNP
cord-293938-40zyv1h8	206	59	Protein	Protein	NNP
cord-293938-40zyv1h8	206	60	as	as	IN
cord-293938-40zyv1h8	206	61	a	a	DT
cord-293938-40zyv1h8	206	62	Receptor	receptor	NN
cord-293938-40zyv1h8	206	63	-	-	HYPH
cord-293938-40zyv1h8	206	64	Destroying	destroy	VBG
cord-293938-40zyv1h8	206	65	Enzyme	Enzyme	NNP
cord-293938-40zyv1h8	206	66	Analysis	Analysis	NNP
cord-293938-40zyv1h8	206	67	of	of	IN
cord-293938-40zyv1h8	206	68	cellular	cellular	JJ
cord-293938-40zyv1h8	206	69	receptors	receptor	NNS
cord-293938-40zyv1h8	206	70	for	for	IN
cord-293938-40zyv1h8	206	71	human	human	JJ
cord-293938-40zyv1h8	206	72	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	206	73	OC43	OC43	NNP
cord-293938-40zyv1h8	206	74	Isolation	Isolation	NNP
cord-293938-40zyv1h8	206	75	and	and	CC
cord-293938-40zyv1h8	206	76	characterization	characterization	NN
cord-293938-40zyv1h8	206	77	of	of	IN
cord-293938-40zyv1h8	206	78	current	current	JJ
cord-293938-40zyv1h8	206	79	human	human	JJ
cord-293938-40zyv1h8	206	80	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	206	81	strains	strain	NNS
cord-293938-40zyv1h8	206	82	in	in	IN
cord-293938-40zyv1h8	206	83	primary	primary	JJ
cord-293938-40zyv1h8	206	84	human	human	JJ
cord-293938-40zyv1h8	206	85	epithelial	epithelial	JJ
cord-293938-40zyv1h8	206	86	cell	cell	NN
cord-293938-40zyv1h8	206	87	cultures	culture	NNS
cord-293938-40zyv1h8	206	88	reveal	reveal	VBP
cord-293938-40zyv1h8	206	89	differences	difference	NNS
cord-293938-40zyv1h8	206	90	in	in	IN
cord-293938-40zyv1h8	206	91	target	target	NN
cord-293938-40zyv1h8	206	92	cell	cell	NN
cord-293938-40zyv1h8	206	93	tropism	tropism	NN
cord-293938-40zyv1h8	206	94	Efficient	efficient	JJ
cord-293938-40zyv1h8	206	95	replication	replication	NN
cord-293938-40zyv1h8	206	96	of	of	IN
cord-293938-40zyv1h8	206	97	the	the	DT
cord-293938-40zyv1h8	206	98	novel	novel	JJ
cord-293938-40zyv1h8	206	99	human	human	JJ
cord-293938-40zyv1h8	206	100	betacoronavirus	betacoronavirus	NNP
cord-293938-40zyv1h8	206	101	EMC	EMC	NNP
cord-293938-40zyv1h8	206	102	on	on	IN
cord-293938-40zyv1h8	206	103	primary	primary	JJ
cord-293938-40zyv1h8	206	104	human	human	JJ
cord-293938-40zyv1h8	206	105	epithelium	epithelium	NN
cord-293938-40zyv1h8	206	106	highlights	highlight	VBZ
cord-293938-40zyv1h8	206	107	its	-PRON-	PRP$
cord-293938-40zyv1h8	206	108	zoonotic	zoonotic	JJ
cord-293938-40zyv1h8	206	109	potential	potential	JJ
cord-293938-40zyv1h8	206	110	Infectious	Infectious	NNP
cord-293938-40zyv1h8	206	111	RNA	RNA	NNP
cord-293938-40zyv1h8	206	112	transcribed	transcribe	VBN
cord-293938-40zyv1h8	206	113	in	in	IN
cord-293938-40zyv1h8	206	114	vitro	vitro	FW
cord-293938-40zyv1h8	206	115	from	from	IN
cord-293938-40zyv1h8	206	116	a	a	DT
cord-293938-40zyv1h8	206	117	cDNA	cdna	NN
cord-293938-40zyv1h8	206	118	copy	copy	NN
cord-293938-40zyv1h8	206	119	of	of	IN
cord-293938-40zyv1h8	206	120	the	the	DT
cord-293938-40zyv1h8	206	121	human	human	JJ
cord-293938-40zyv1h8	206	122	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	206	123	genome	genome	NN
cord-293938-40zyv1h8	206	124	cloned	clone	VBN
cord-293938-40zyv1h8	206	125	in	in	IN
cord-293938-40zyv1h8	206	126	vaccinia	vaccinia	NN
cord-293938-40zyv1h8	206	127	virus	virus	NN
cord-293938-40zyv1h8	206	128	Recovery	recovery	NN
cord-293938-40zyv1h8	206	129	of	of	IN
cord-293938-40zyv1h8	206	130	a	a	DT
cord-293938-40zyv1h8	206	131	neurovirulent	neurovirulent	NN
cord-293938-40zyv1h8	206	132	human	human	JJ
cord-293938-40zyv1h8	206	133	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	206	134	OC43	OC43	NNP
cord-293938-40zyv1h8	206	135	from	from	IN
cord-293938-40zyv1h8	206	136	an	an	DT
cord-293938-40zyv1h8	206	137	infectious	infectious	JJ
cord-293938-40zyv1h8	206	138	cDNA	cdna	NN
cord-293938-40zyv1h8	206	139	clone	clone	NN
cord-293938-40zyv1h8	206	140	Systematic	systematic	JJ
cord-293938-40zyv1h8	206	141	assembly	assembly	NN
cord-293938-40zyv1h8	206	142	of	of	IN
cord-293938-40zyv1h8	206	143	a	a	DT
cord-293938-40zyv1h8	206	144	full	full	JJ
cord-293938-40zyv1h8	206	145	-	-	HYPH
cord-293938-40zyv1h8	206	146	length	length	NN
cord-293938-40zyv1h8	206	147	infectious	infectious	JJ
cord-293938-40zyv1h8	206	148	clone	clone	NN
cord-293938-40zyv1h8	206	149	of	of	IN
cord-293938-40zyv1h8	206	150	human	human	JJ
cord-293938-40zyv1h8	206	151	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	206	152	NL63	NL63	NNP
cord-293938-40zyv1h8	206	153	Animal	Animal	NNP
cord-293938-40zyv1h8	206	154	models	model	NNS
cord-293938-40zyv1h8	206	155	for	for	IN
cord-293938-40zyv1h8	206	156	the	the	DT
cord-293938-40zyv1h8	206	157	study	study	NN
cord-293938-40zyv1h8	206	158	of	of	IN
cord-293938-40zyv1h8	206	159	influenza	influenza	NN
cord-293938-40zyv1h8	206	160	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	206	161	and	and	CC
cord-293938-40zyv1h8	206	162	therapy	therapy	NN
cord-293938-40zyv1h8	206	163	Animal	Animal	NNP
cord-293938-40zyv1h8	206	164	models	model	NNS
cord-293938-40zyv1h8	206	165	for	for	IN
cord-293938-40zyv1h8	206	166	SARS	SARS	NNP
cord-293938-40zyv1h8	206	167	and	and	CC
cord-293938-40zyv1h8	206	168	MERS	MERS	NNP
cord-293938-40zyv1h8	207	1	coronaviruses	coronaviruses	NNP
cord-293938-40zyv1h8	207	2	Development	Development	NNP
cord-293938-40zyv1h8	207	3	of	of	IN
cord-293938-40zyv1h8	207	4	a	a	DT
cord-293938-40zyv1h8	207	5	transgenic	transgenic	JJ
cord-293938-40zyv1h8	207	6	mouse	mouse	NN
cord-293938-40zyv1h8	207	7	model	model	NN
cord-293938-40zyv1h8	207	8	susceptible	susceptible	JJ
cord-293938-40zyv1h8	207	9	to	to	IN
cord-293938-40zyv1h8	207	10	human	human	JJ
cord-293938-40zyv1h8	207	11	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	207	12	229E	229e	CD
cord-293938-40zyv1h8	207	13	Cells	cell	NNS
cord-293938-40zyv1h8	207	14	of	of	IN
cord-293938-40zyv1h8	207	15	human	human	JJ
cord-293938-40zyv1h8	207	16	aminopeptidase	aminopeptidase	NN
cord-293938-40zyv1h8	208	1	N	N	NNP
cord-293938-40zyv1h8	208	2	(	(	-LRB-
cord-293938-40zyv1h8	208	3	CD13	CD13	NNP
cord-293938-40zyv1h8	208	4	)	)	-RRB-
cord-293938-40zyv1h8	208	5	transgenic	transgenic	JJ
cord-293938-40zyv1h8	208	6	mice	mouse	NNS
cord-293938-40zyv1h8	208	7	are	be	VBP
cord-293938-40zyv1h8	208	8	infected	infect	VBN
cord-293938-40zyv1h8	208	9	by	by	IN
cord-293938-40zyv1h8	208	10	human	human	JJ
cord-293938-40zyv1h8	208	11	coronavirus-229E	coronavirus-229E	NNS
cord-293938-40zyv1h8	208	12	in	in	IN
cord-293938-40zyv1h8	208	13	vitro	vitro	FW
cord-293938-40zyv1h8	208	14	,	,	,
cord-293938-40zyv1h8	208	15	but	but	CC
cord-293938-40zyv1h8	208	16	not	not	RB
cord-293938-40zyv1h8	208	17	in	in	IN
cord-293938-40zyv1h8	208	18	vivo	vivo	NNP
cord-293938-40zyv1h8	208	19	Rapid	rapid	JJ
cord-293938-40zyv1h8	208	20	generation	generation	NN
cord-293938-40zyv1h8	208	21	of	of	IN
cord-293938-40zyv1h8	208	22	a	a	DT
cord-293938-40zyv1h8	208	23	mouse	mouse	NN
cord-293938-40zyv1h8	208	24	model	model	NN
cord-293938-40zyv1h8	208	25	for	for	IN
cord-293938-40zyv1h8	208	26	Middle	Middle	NNP
cord-293938-40zyv1h8	208	27	East	East	NNP
cord-293938-40zyv1h8	208	28	respiratory	respiratory	JJ
cord-293938-40zyv1h8	208	29	syndrome	syndrome	NN
cord-293938-40zyv1h8	208	30	Generation	generation	NN
cord-293938-40zyv1h8	208	31	of	of	IN
cord-293938-40zyv1h8	208	32	a	a	DT
cord-293938-40zyv1h8	208	33	transgenic	transgenic	JJ
cord-293938-40zyv1h8	208	34	mouse	mouse	NN
cord-293938-40zyv1h8	208	35	model	model	NN
cord-293938-40zyv1h8	208	36	of	of	IN
cord-293938-40zyv1h8	208	37	Middle	Middle	NNP
cord-293938-40zyv1h8	208	38	East	East	NNP
cord-293938-40zyv1h8	208	39	respiratory	respiratory	JJ
cord-293938-40zyv1h8	208	40	syndrome	syndrome	NN
cord-293938-40zyv1h8	208	41	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	208	42	infection	infection	NN
cord-293938-40zyv1h8	208	43	and	and	CC
cord-293938-40zyv1h8	208	44	disease	disease	NN
cord-293938-40zyv1h8	208	45	Human	Human	NNP
cord-293938-40zyv1h8	208	46	parainfluenza	parainfluenza	NNP
cord-293938-40zyv1h8	208	47	virus	virus	NN
cord-293938-40zyv1h8	208	48	serotypes	serotype	NNS
cord-293938-40zyv1h8	208	49	differ	differ	VBP
cord-293938-40zyv1h8	208	50	in	in	IN
cord-293938-40zyv1h8	208	51	their	-PRON-	PRP$
cord-293938-40zyv1h8	208	52	kinetics	kinetic	NNS
cord-293938-40zyv1h8	208	53	of	of	IN
cord-293938-40zyv1h8	208	54	replication	replication	NN
cord-293938-40zyv1h8	208	55	and	and	CC
cord-293938-40zyv1h8	208	56	cytokine	cytokine	JJ
cord-293938-40zyv1h8	208	57	secretion	secretion	NN
cord-293938-40zyv1h8	208	58	in	in	IN
cord-293938-40zyv1h8	208	59	human	human	JJ
cord-293938-40zyv1h8	208	60	tracheobronchial	tracheobronchial	JJ
cord-293938-40zyv1h8	208	61	airway	airway	NN
cord-293938-40zyv1h8	208	62	epithelium	epithelium	NN
cord-293938-40zyv1h8	208	63	Human	Human	NNP
cord-293938-40zyv1h8	208	64	bocavirus	bocavirus	NN
cord-293938-40zyv1h8	208	65	1	1	CD
cord-293938-40zyv1h8	208	66	infects	infect	VBZ
cord-293938-40zyv1h8	208	67	commercially	commercially	RB
cord-293938-40zyv1h8	208	68	available	available	JJ
cord-293938-40zyv1h8	208	69	primary	primary	JJ
cord-293938-40zyv1h8	208	70	human	human	JJ
cord-293938-40zyv1h8	208	71	airway	airway	NN
cord-293938-40zyv1h8	208	72	epithelium	epithelium	NN
cord-293938-40zyv1h8	208	73	cultures	culture	NNS
cord-293938-40zyv1h8	208	74	productively	productively	RB
cord-293938-40zyv1h8	208	75	Infection	infection	NN
cord-293938-40zyv1h8	208	76	of	of	IN
cord-293938-40zyv1h8	208	77	human	human	JJ
cord-293938-40zyv1h8	208	78	airway	airway	NN
cord-293938-40zyv1h8	208	79	epithelium	epithelium	NN
cord-293938-40zyv1h8	208	80	by	by	IN
cord-293938-40zyv1h8	208	81	human	human	JJ
cord-293938-40zyv1h8	208	82	and	and	CC
cord-293938-40zyv1h8	208	83	avian	avian	JJ
cord-293938-40zyv1h8	208	84	strains	strain	NNS
cord-293938-40zyv1h8	208	85	of	of	IN
cord-293938-40zyv1h8	208	86	influenza	influenza	NN
cord-293938-40zyv1h8	209	1	a	a	DT
cord-293938-40zyv1h8	209	2	virus	virus	NN
cord-293938-40zyv1h8	209	3	Human	Human	NNP
cord-293938-40zyv1h8	209	4	bocavirus	bocavirus	NN
cord-293938-40zyv1h8	209	5	can	can	MD
cord-293938-40zyv1h8	209	6	be	be	VB
cord-293938-40zyv1h8	209	7	cultured	culture	VBN
cord-293938-40zyv1h8	209	8	in	in	IN
cord-293938-40zyv1h8	209	9	differentiated	differentiated	JJ
cord-293938-40zyv1h8	209	10	human	human	JJ
cord-293938-40zyv1h8	209	11	airway	airway	NN
cord-293938-40zyv1h8	209	12	epithelial	epithelial	JJ
cord-293938-40zyv1h8	209	13	cells	cell	NNS
cord-293938-40zyv1h8	209	14	Non	non	JJ
cord-293938-40zyv1h8	209	15	-	-	JJ
cord-293938-40zyv1h8	209	16	animal	animal	JJ
cord-293938-40zyv1h8	209	17	models	model	NNS
cord-293938-40zyv1h8	209	18	of	of	IN
cord-293938-40zyv1h8	209	19	epithelial	epithelial	JJ
cord-293938-40zyv1h8	209	20	barriers	barrier	NNS
cord-293938-40zyv1h8	209	21	(	(	-LRB-
cord-293938-40zyv1h8	209	22	skin	skin	NN
cord-293938-40zyv1h8	209	23	,	,	,
cord-293938-40zyv1h8	209	24	intestine	intestine	NN
cord-293938-40zyv1h8	209	25	and	and	CC
cord-293938-40zyv1h8	209	26	lung	lung	NN
cord-293938-40zyv1h8	209	27	)	)	-RRB-
cord-293938-40zyv1h8	209	28	in	in	IN
cord-293938-40zyv1h8	209	29	research	research	NN
cord-293938-40zyv1h8	209	30	,	,	,
cord-293938-40zyv1h8	209	31	industrial	industrial	JJ
cord-293938-40zyv1h8	209	32	applications	application	NNS
cord-293938-40zyv1h8	209	33	and	and	CC
cord-293938-40zyv1h8	209	34	regulatory	regulatory	JJ
cord-293938-40zyv1h8	209	35	toxicology	toxicology	NN
cord-293938-40zyv1h8	209	36	Airway	Airway	NNP
cord-293938-40zyv1h8	209	37	epithelial	epithelial	JJ
cord-293938-40zyv1h8	209	38	cells	cell	NNS
cord-293938-40zyv1h8	209	39	:	:	:
cord-293938-40zyv1h8	209	40	current	current	JJ
cord-293938-40zyv1h8	209	41	concepts	concept	NNS
cord-293938-40zyv1h8	209	42	and	and	CC
cord-293938-40zyv1h8	209	43	challenges	challenge	VBZ
cord-293938-40zyv1h8	209	44	Alveolar	alveolar	JJ
cord-293938-40zyv1h8	209	45	development	development	NN
cord-293938-40zyv1h8	209	46	and	and	CC
cord-293938-40zyv1h8	209	47	disease	disease	NN
cord-293938-40zyv1h8	209	48	Building	Building	NNP
cord-293938-40zyv1h8	209	49	and	and	CC
cord-293938-40zyv1h8	209	50	maintaining	maintain	VBG
cord-293938-40zyv1h8	209	51	the	the	DT
cord-293938-40zyv1h8	209	52	epithelium	epithelium	NN
cord-293938-40zyv1h8	209	53	of	of	IN
cord-293938-40zyv1h8	209	54	the	the	DT
cord-293938-40zyv1h8	209	55	lung	lung	NN
cord-293938-40zyv1h8	209	56	Serial	serial	JJ
cord-293938-40zyv1h8	209	57	culturing	culturing	NN
cord-293938-40zyv1h8	209	58	of	of	IN
cord-293938-40zyv1h8	209	59	human	human	JJ
cord-293938-40zyv1h8	209	60	bronchial	bronchial	JJ
cord-293938-40zyv1h8	209	61	epithelial	epithelial	JJ
cord-293938-40zyv1h8	209	62	cells	cell	NNS
cord-293938-40zyv1h8	209	63	derived	derive	VBN
cord-293938-40zyv1h8	209	64	from	from	IN
cord-293938-40zyv1h8	209	65	biopsies	biopsy	NNS
cord-293938-40zyv1h8	209	66	Ciliogenesis	Ciliogenesis	NNP
cord-293938-40zyv1h8	209	67	in	in	IN
cord-293938-40zyv1h8	209	68	human	human	JJ
cord-293938-40zyv1h8	209	69	bronchial	bronchial	JJ
cord-293938-40zyv1h8	209	70	epithelial	epithelial	JJ
cord-293938-40zyv1h8	209	71	cells	cell	NNS
cord-293938-40zyv1h8	209	72	cultured	culture	VBN
cord-293938-40zyv1h8	209	73	at	at	IN
cord-293938-40zyv1h8	209	74	the	the	DT
cord-293938-40zyv1h8	209	75	air	air	NN
cord-293938-40zyv1h8	209	76	-	-	HYPH
cord-293938-40zyv1h8	209	77	liquid	liquid	NN
cord-293938-40zyv1h8	209	78	interface	interface	NN
cord-293938-40zyv1h8	210	1	The	the	DT
cord-293938-40zyv1h8	210	2	air	air	NN
cord-293938-40zyv1h8	210	3	-	-	HYPH
cord-293938-40zyv1h8	210	4	liquid	liquid	NN
cord-293938-40zyv1h8	210	5	interface	interface	NN
cord-293938-40zyv1h8	210	6	and	and	CC
cord-293938-40zyv1h8	210	7	use	use	NN
cord-293938-40zyv1h8	210	8	of	of	IN
cord-293938-40zyv1h8	210	9	primary	primary	JJ
cord-293938-40zyv1h8	210	10	cell	cell	NN
cord-293938-40zyv1h8	210	11	cultures	culture	NNS
cord-293938-40zyv1h8	210	12	are	be	VBP
cord-293938-40zyv1h8	210	13	important	important	JJ
cord-293938-40zyv1h8	210	14	to	to	TO
cord-293938-40zyv1h8	210	15	recapitulate	recapitulate	VB
cord-293938-40zyv1h8	210	16	the	the	DT
cord-293938-40zyv1h8	210	17	transcriptional	transcriptional	JJ
cord-293938-40zyv1h8	210	18	profile	profile	NN
cord-293938-40zyv1h8	210	19	of	of	IN
cord-293938-40zyv1h8	210	20	in	in	IN
cord-293938-40zyv1h8	210	21	vivo	vivo	NNP
cord-293938-40zyv1h8	210	22	airway	airway	NN
cord-293938-40zyv1h8	210	23	epithelia	epithelium	NNS
cord-293938-40zyv1h8	210	24	Bilateral	bilateral	JJ
cord-293938-40zyv1h8	210	25	entry	entry	NN
cord-293938-40zyv1h8	210	26	and	and	CC
cord-293938-40zyv1h8	210	27	release	release	NN
cord-293938-40zyv1h8	210	28	of	of	IN
cord-293938-40zyv1h8	210	29	Middle	Middle	NNP
cord-293938-40zyv1h8	210	30	East	East	NNP
cord-293938-40zyv1h8	210	31	respiratory	respiratory	JJ
cord-293938-40zyv1h8	210	32	syndrome	syndrome	NN
cord-293938-40zyv1h8	210	33	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	211	1	induces	induce	VBZ
cord-293938-40zyv1h8	211	2	profound	profound	JJ
cord-293938-40zyv1h8	211	3	apoptosis	apoptosis	NN
cord-293938-40zyv1h8	211	4	of	of	IN
cord-293938-40zyv1h8	211	5	human	human	JJ
cord-293938-40zyv1h8	211	6	bronchial	bronchial	JJ
cord-293938-40zyv1h8	211	7	epithelial	epithelial	JJ
cord-293938-40zyv1h8	211	8	cells	cell	NNS
cord-293938-40zyv1h8	212	1	Innate	innate	JJ
cord-293938-40zyv1h8	212	2	immune	immune	JJ
cord-293938-40zyv1h8	212	3	response	response	NN
cord-293938-40zyv1h8	212	4	of	of	IN
cord-293938-40zyv1h8	212	5	human	human	JJ
cord-293938-40zyv1h8	212	6	alveolar	alveolar	NN
cord-293938-40zyv1h8	212	7	type	type	NN
cord-293938-40zyv1h8	212	8	II	II	NNP
cord-293938-40zyv1h8	212	9	cells	cell	NNS
cord-293938-40zyv1h8	212	10	infected	infect	VBN
cord-293938-40zyv1h8	212	11	with	with	IN
cord-293938-40zyv1h8	212	12	severe	severe	JJ
cord-293938-40zyv1h8	212	13	acute	acute	JJ
cord-293938-40zyv1h8	212	14	respiratory	respiratory	JJ
cord-293938-40zyv1h8	212	15	syndrome	syndrome	NN
cord-293938-40zyv1h8	212	16	-	-	HYPH
cord-293938-40zyv1h8	212	17	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	212	18	Human	human	JJ
cord-293938-40zyv1h8	212	19	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	212	20	HKU1	hku1	CD
cord-293938-40zyv1h8	212	21	infection	infection	NN
cord-293938-40zyv1h8	212	22	of	of	IN
cord-293938-40zyv1h8	212	23	primary	primary	JJ
cord-293938-40zyv1h8	212	24	human	human	JJ
cord-293938-40zyv1h8	212	25	type	type	NN
cord-293938-40zyv1h8	212	26	II	ii	CD
cord-293938-40zyv1h8	212	27	alveolar	alveolar	NN
cord-293938-40zyv1h8	212	28	epithelial	epithelial	JJ
cord-293938-40zyv1h8	212	29	cells	cell	NNS
cord-293938-40zyv1h8	212	30	:	:	:
cord-293938-40zyv1h8	212	31	cytopathic	cytopathic	JJ
cord-293938-40zyv1h8	212	32	effects	effect	NNS
cord-293938-40zyv1h8	212	33	and	and	CC
cord-293938-40zyv1h8	212	34	innate	innate	JJ
cord-293938-40zyv1h8	212	35	immune	immune	JJ
cord-293938-40zyv1h8	212	36	response	response	NN
cord-293938-40zyv1h8	213	1	Transcriptome	Transcriptome	NNP
cord-293938-40zyv1h8	213	2	analysis	analysis	NN
cord-293938-40zyv1h8	213	3	reveals	reveal	VBZ
cord-293938-40zyv1h8	213	4	a	a	DT
cord-293938-40zyv1h8	213	5	classical	classical	JJ
cord-293938-40zyv1h8	213	6	interferon	interferon	NN
cord-293938-40zyv1h8	213	7	signature	signature	NN
cord-293938-40zyv1h8	213	8	induced	induce	VBN
cord-293938-40zyv1h8	213	9	by	by	IN
cord-293938-40zyv1h8	213	10	IFNlambda4	IFNlambda4	NNP
cord-293938-40zyv1h8	213	11	in	in	IN
cord-293938-40zyv1h8	213	12	human	human	JJ
cord-293938-40zyv1h8	213	13	primary	primary	JJ
cord-293938-40zyv1h8	213	14	cells	cell	NNS
cord-293938-40zyv1h8	214	1	SARS	SARS	NNP
cord-293938-40zyv1h8	214	2	-	-	HYPH
cord-293938-40zyv1h8	214	3	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	214	4	replication	replication	NN
cord-293938-40zyv1h8	214	5	/	/	SYM
cord-293938-40zyv1h8	214	6	transcription	transcription	NN
cord-293938-40zyv1h8	214	7	complexes	complex	NNS
cord-293938-40zyv1h8	214	8	are	be	VBP
cord-293938-40zyv1h8	214	9	membrane	membrane	NN
cord-293938-40zyv1h8	214	10	-	-	HYPH
cord-293938-40zyv1h8	214	11	protected	protect	VBN
cord-293938-40zyv1h8	214	12	and	and	CC
cord-293938-40zyv1h8	214	13	need	need	VB
cord-293938-40zyv1h8	214	14	a	a	DT
cord-293938-40zyv1h8	214	15	host	host	NN
cord-293938-40zyv1h8	214	16	factor	factor	NN
cord-293938-40zyv1h8	214	17	for	for	IN
cord-293938-40zyv1h8	214	18	activity	activity	NN
cord-293938-40zyv1h8	214	19	in	in	IN
cord-293938-40zyv1h8	214	20	vitro	vitro	FW
cord-293938-40zyv1h8	214	21	SARS	SARS	NNP
cord-293938-40zyv1h8	214	22	-	-	HYPH
cord-293938-40zyv1h8	214	23	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	214	24	replication	replication	NN
cord-293938-40zyv1h8	214	25	is	be	VBZ
cord-293938-40zyv1h8	214	26	supported	support	VBN
cord-293938-40zyv1h8	214	27	by	by	IN
cord-293938-40zyv1h8	214	28	a	a	DT
cord-293938-40zyv1h8	214	29	reticulovesicular	reticulovesicular	JJ
cord-293938-40zyv1h8	214	30	network	network	NN
cord-293938-40zyv1h8	214	31	of	of	IN
cord-293938-40zyv1h8	214	32	modified	modify	VBN
cord-293938-40zyv1h8	214	33	endoplasmic	endoplasmic	NN
cord-293938-40zyv1h8	214	34	reticulum	reticulum	NN
cord-293938-40zyv1h8	214	35	2'-O	2'-o	CD
cord-293938-40zyv1h8	214	36	methylation	methylation	NN
cord-293938-40zyv1h8	214	37	of	of	IN
cord-293938-40zyv1h8	214	38	the	the	DT
cord-293938-40zyv1h8	214	39	viral	viral	JJ
cord-293938-40zyv1h8	214	40	mRNA	mRNA	NNP
cord-293938-40zyv1h8	214	41	cap	cap	NN
cord-293938-40zyv1h8	214	42	evades	evade	VBZ
cord-293938-40zyv1h8	214	43	host	host	NN
cord-293938-40zyv1h8	214	44	restriction	restriction	NN
cord-293938-40zyv1h8	214	45	by	by	IN
cord-293938-40zyv1h8	214	46	IFIT	IFIT	NNP
cord-293938-40zyv1h8	214	47	family	family	NN
cord-293938-40zyv1h8	214	48	members	member	NNS
cord-293938-40zyv1h8	215	1	Ribose	ribose	NN
cord-293938-40zyv1h8	215	2	2'-O	2'-o	CD
cord-293938-40zyv1h8	215	3	-	-	HYPH
cord-293938-40zyv1h8	215	4	methylation	methylation	NN
cord-293938-40zyv1h8	215	5	provides	provide	VBZ
cord-293938-40zyv1h8	215	6	a	a	DT
cord-293938-40zyv1h8	215	7	molecular	molecular	JJ
cord-293938-40zyv1h8	215	8	signature	signature	NN
cord-293938-40zyv1h8	215	9	for	for	IN
cord-293938-40zyv1h8	215	10	the	the	DT
cord-293938-40zyv1h8	215	11	distinction	distinction	NN
cord-293938-40zyv1h8	215	12	of	of	IN
cord-293938-40zyv1h8	215	13	self	self	NN
cord-293938-40zyv1h8	215	14	and	and	CC
cord-293938-40zyv1h8	215	15	non	non	JJ
cord-293938-40zyv1h8	215	16	-	-	JJ
cord-293938-40zyv1h8	215	17	self	self	JJ
cord-293938-40zyv1h8	215	18	mRNA	mrna	NN
cord-293938-40zyv1h8	215	19	dependent	dependent	JJ
cord-293938-40zyv1h8	215	20	on	on	IN
cord-293938-40zyv1h8	215	21	the	the	DT
cord-293938-40zyv1h8	215	22	RNA	RNA	NNP
cord-293938-40zyv1h8	215	23	sensor	sensor	NN
cord-293938-40zyv1h8	216	1	Mda5	Mda5	NNP
cord-293938-40zyv1h8	216	2	Middle	Middle	NNP
cord-293938-40zyv1h8	216	3	east	east	JJ
cord-293938-40zyv1h8	216	4	respiratory	respiratory	JJ
cord-293938-40zyv1h8	216	5	syndrome	syndrome	NN
cord-293938-40zyv1h8	216	6	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	216	7	4a	4a	CD
cord-293938-40zyv1h8	216	8	protein	protein	NN
cord-293938-40zyv1h8	216	9	is	be	VBZ
cord-293938-40zyv1h8	216	10	a	a	DT
cord-293938-40zyv1h8	216	11	double	double	RB
cord-293938-40zyv1h8	216	12	-	-	HYPH
cord-293938-40zyv1h8	216	13	stranded	stranded	JJ
cord-293938-40zyv1h8	216	14	RNAbinding	rnabinding	NN
cord-293938-40zyv1h8	216	15	protein	protein	NN
cord-293938-40zyv1h8	216	16	that	that	WDT
cord-293938-40zyv1h8	216	17	suppresses	suppress	VBZ
cord-293938-40zyv1h8	216	18	PACT	pact	NN
cord-293938-40zyv1h8	216	19	-	-	HYPH
cord-293938-40zyv1h8	216	20	induced	induce	VBN
cord-293938-40zyv1h8	216	21	activation	activation	NN
cord-293938-40zyv1h8	216	22	of	of	IN
cord-293938-40zyv1h8	216	23	RIG	rig	NN
cord-293938-40zyv1h8	216	24	-	-	:
cord-293938-40zyv1h8	216	25	I	I	NNP
cord-293938-40zyv1h8	216	26	and	and	CC
cord-293938-40zyv1h8	216	27	MDA5	MDA5	NNP
cord-293938-40zyv1h8	216	28	in	in	IN
cord-293938-40zyv1h8	216	29	the	the	DT
cord-293938-40zyv1h8	216	30	innate	innate	JJ
cord-293938-40zyv1h8	216	31	antiviral	antiviral	JJ
cord-293938-40zyv1h8	216	32	response	response	NN
cord-293938-40zyv1h8	216	33	Middle	Middle	NNP
cord-293938-40zyv1h8	216	34	East	East	NNP
cord-293938-40zyv1h8	216	35	respiratory	respiratory	JJ
cord-293938-40zyv1h8	216	36	syndrome	syndrome	NN
cord-293938-40zyv1h8	216	37	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	216	38	accessory	accessory	NN
cord-293938-40zyv1h8	216	39	protein	protein	NN
cord-293938-40zyv1h8	216	40	4a	4a	CD
cord-293938-40zyv1h8	216	41	is	be	VBZ
cord-293938-40zyv1h8	216	42	a	a	DT
cord-293938-40zyv1h8	216	43	type	type	NN
cord-293938-40zyv1h8	217	1	I	-PRON-	PRP
cord-293938-40zyv1h8	217	2	interferon	interferon	VBD
cord-293938-40zyv1h8	217	3	antagonist	antagonist	NN
cord-293938-40zyv1h8	218	1	The	the	DT
cord-293938-40zyv1h8	218	2	ORF4b	orf4b	RB
cord-293938-40zyv1h8	218	3	-	-	HYPH
cord-293938-40zyv1h8	218	4	encoded	encode	VBN
cord-293938-40zyv1h8	218	5	accessory	accessory	NN
cord-293938-40zyv1h8	218	6	proteins	protein	NNS
cord-293938-40zyv1h8	218	7	of	of	IN
cord-293938-40zyv1h8	218	8	Middle	Middle	NNP
cord-293938-40zyv1h8	218	9	East	East	NNP
cord-293938-40zyv1h8	218	10	respiratory	respiratory	JJ
cord-293938-40zyv1h8	218	11	syndrome	syndrome	NN
cord-293938-40zyv1h8	218	12	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	218	13	and	and	CC
cord-293938-40zyv1h8	218	14	two	two	CD
cord-293938-40zyv1h8	218	15	related	related	JJ
cord-293938-40zyv1h8	218	16	bat	bat	NN
cord-293938-40zyv1h8	218	17	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	218	18	localize	localize	VBP
cord-293938-40zyv1h8	218	19	to	to	IN
cord-293938-40zyv1h8	218	20	the	the	DT
cord-293938-40zyv1h8	218	21	nucleus	nucleus	NN
cord-293938-40zyv1h8	218	22	and	and	CC
cord-293938-40zyv1h8	218	23	inhibit	inhibit	VB
cord-293938-40zyv1h8	218	24	innate	innate	JJ
cord-293938-40zyv1h8	218	25	immune	immune	JJ
cord-293938-40zyv1h8	218	26	signalling	signal	VBG
cord-293938-40zyv1h8	218	27	Severe	severe	JJ
cord-293938-40zyv1h8	218	28	acute	acute	JJ
cord-293938-40zyv1h8	218	29	respiratory	respiratory	JJ
cord-293938-40zyv1h8	218	30	syndrome	syndrome	NN
cord-293938-40zyv1h8	218	31	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	218	32	open	open	JJ
cord-293938-40zyv1h8	218	33	reading	reading	NN
cord-293938-40zyv1h8	218	34	frame	frame	NN
cord-293938-40zyv1h8	218	35	(	(	-LRB-
cord-293938-40zyv1h8	218	36	ORF	ORF	NNP
cord-293938-40zyv1h8	218	37	)	)	-RRB-
cord-293938-40zyv1h8	218	38	3b	3b	NNP
cord-293938-40zyv1h8	218	39	,	,	,
cord-293938-40zyv1h8	218	40	ORF	ORF	NNP
cord-293938-40zyv1h8	218	41	6	6	CD
cord-293938-40zyv1h8	218	42	,	,	,
cord-293938-40zyv1h8	218	43	and	and	CC
cord-293938-40zyv1h8	218	44	nucleocapsid	nucleocapsid	NN
cord-293938-40zyv1h8	218	45	proteins	protein	NNS
cord-293938-40zyv1h8	218	46	function	function	VBP
cord-293938-40zyv1h8	218	47	as	as	IN
cord-293938-40zyv1h8	218	48	interferon	interferon	NN
cord-293938-40zyv1h8	218	49	antagonists	antagonist	NNS
cord-293938-40zyv1h8	219	1	Severe	severe	JJ
cord-293938-40zyv1h8	219	2	acute	acute	JJ
cord-293938-40zyv1h8	219	3	respiratory	respiratory	JJ
cord-293938-40zyv1h8	219	4	syndrome	syndrome	NN
cord-293938-40zyv1h8	219	5	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	219	6	ORF6	ORF6	NNP
cord-293938-40zyv1h8	219	7	antagonizes	antagonize	VBZ
cord-293938-40zyv1h8	219	8	STAT1	stat1	NN
cord-293938-40zyv1h8	219	9	function	function	NN
cord-293938-40zyv1h8	219	10	by	by	IN
cord-293938-40zyv1h8	219	11	sequestering	sequester	VBG
cord-293938-40zyv1h8	219	12	nuclear	nuclear	JJ
cord-293938-40zyv1h8	219	13	import	import	NN
cord-293938-40zyv1h8	219	14	factors	factor	NNS
cord-293938-40zyv1h8	219	15	on	on	IN
cord-293938-40zyv1h8	219	16	the	the	DT
cord-293938-40zyv1h8	219	17	rough	rough	JJ
cord-293938-40zyv1h8	219	18	endoplasmic	endoplasmic	NN
cord-293938-40zyv1h8	219	19	reticulum	reticulum	NN
cord-293938-40zyv1h8	219	20	/	/	SYM
cord-293938-40zyv1h8	219	21	Golgi	Golgi	NNP
cord-293938-40zyv1h8	219	22	membrane	membrane	NN
cord-293938-40zyv1h8	219	23	Severe	severe	JJ
cord-293938-40zyv1h8	219	24	acute	acute	JJ
cord-293938-40zyv1h8	219	25	respiratory	respiratory	JJ
cord-293938-40zyv1h8	219	26	syndrome	syndrome	NN
cord-293938-40zyv1h8	219	27	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	219	28	spike	spike	NN
cord-293938-40zyv1h8	219	29	protein	protein	NN
cord-293938-40zyv1h8	219	30	expressed	express	VBN
cord-293938-40zyv1h8	219	31	by	by	IN
cord-293938-40zyv1h8	219	32	attenuated	attenuated	JJ
cord-293938-40zyv1h8	219	33	vaccinia	vaccinia	NN
cord-293938-40zyv1h8	219	34	virus	virus	NN
cord-293938-40zyv1h8	219	35	protectively	protectively	RB
cord-293938-40zyv1h8	219	36	immunizes	immunize	VBZ
cord-293938-40zyv1h8	219	37	mice	mouse	NNS
cord-293938-40zyv1h8	219	38	Protective	protective	JJ
cord-293938-40zyv1h8	219	39	efficacy	efficacy	NN
cord-293938-40zyv1h8	219	40	of	of	IN
cord-293938-40zyv1h8	219	41	recombinant	recombinant	JJ
cord-293938-40zyv1h8	219	42	modified	modify	VBN
cord-293938-40zyv1h8	219	43	vaccinia	vaccinia	NN
cord-293938-40zyv1h8	219	44	virus	virus	NN
cord-293938-40zyv1h8	219	45	Ankara	Ankara	NNP
cord-293938-40zyv1h8	219	46	delivering	deliver	VBG
cord-293938-40zyv1h8	219	47	Middle	Middle	NNP
cord-293938-40zyv1h8	219	48	East	East	NNP
cord-293938-40zyv1h8	219	49	respiratory	respiratory	JJ
cord-293938-40zyv1h8	219	50	syndrome	syndrome	NN
cord-293938-40zyv1h8	219	51	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	219	52	spike	spike	NN
cord-293938-40zyv1h8	219	53	glycoprotein	glycoprotein	NN
cord-293938-40zyv1h8	219	54	Ribavirin	ribavirin	NN
cord-293938-40zyv1h8	219	55	and	and	CC
cord-293938-40zyv1h8	219	56	interferon	interferon	NN
cord-293938-40zyv1h8	219	57	therapy	therapy	NN
cord-293938-40zyv1h8	219	58	in	in	IN
cord-293938-40zyv1h8	219	59	patients	patient	NNS
cord-293938-40zyv1h8	219	60	infected	infect	VBN
cord-293938-40zyv1h8	219	61	with	with	IN
cord-293938-40zyv1h8	219	62	the	the	DT
cord-293938-40zyv1h8	219	63	Middle	Middle	NNP
cord-293938-40zyv1h8	219	64	East	East	NNP
cord-293938-40zyv1h8	219	65	respiratory	respiratory	JJ
cord-293938-40zyv1h8	219	66	syndrome	syndrome	NN
cord-293938-40zyv1h8	219	67	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	219	68	:	:	:
cord-293938-40zyv1h8	219	69	an	an	DT
cord-293938-40zyv1h8	219	70	observational	observational	JJ
cord-293938-40zyv1h8	219	71	study	study	NN
cord-293938-40zyv1h8	219	72	Hostdirected	hostdirecte	VBN
cord-293938-40zyv1h8	219	73	therapies	therapy	NNS
cord-293938-40zyv1h8	219	74	for	for	IN
cord-293938-40zyv1h8	219	75	improving	improve	VBG
cord-293938-40zyv1h8	219	76	poor	poor	JJ
cord-293938-40zyv1h8	219	77	treatment	treatment	NN
cord-293938-40zyv1h8	219	78	outcomes	outcome	NNS
cord-293938-40zyv1h8	219	79	associated	associate	VBN
cord-293938-40zyv1h8	219	80	with	with	IN
cord-293938-40zyv1h8	219	81	the	the	DT
cord-293938-40zyv1h8	219	82	middle	middle	NNP
cord-293938-40zyv1h8	219	83	east	east	NNP
cord-293938-40zyv1h8	219	84	respiratory	respiratory	JJ
cord-293938-40zyv1h8	219	85	syndrome	syndrome	NN
cord-293938-40zyv1h8	219	86	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	219	87	infections	infection	NNS
cord-293938-40zyv1h8	219	88	Ribavirin	ribavirin	RB
cord-293938-40zyv1h8	219	89	and	and	CC
cord-293938-40zyv1h8	219	90	interferon	interferon	NN
cord-293938-40zyv1h8	220	1	alfa-2a	alfa-2a	JJ
cord-293938-40zyv1h8	220	2	for	for	IN
cord-293938-40zyv1h8	220	3	severe	severe	JJ
cord-293938-40zyv1h8	220	4	Middle	Middle	NNP
cord-293938-40zyv1h8	220	5	East	East	NNP
cord-293938-40zyv1h8	220	6	respiratory	respiratory	JJ
cord-293938-40zyv1h8	220	7	syndrome	syndrome	NN
cord-293938-40zyv1h8	220	8	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	220	9	infection	infection	NN
cord-293938-40zyv1h8	220	10	:	:	:
cord-293938-40zyv1h8	220	11	a	a	DT
cord-293938-40zyv1h8	220	12	retrospective	retrospective	JJ
cord-293938-40zyv1h8	220	13	cohort	cohort	NN
cord-293938-40zyv1h8	220	14	study	study	NN
cord-293938-40zyv1h8	220	15	IFN	IFN	NNP
cord-293938-40zyv1h8	220	16	-	-	HYPH
cord-293938-40zyv1h8	220	17	alpha2a	alpha2a	NNP
cord-293938-40zyv1h8	221	1	or	or	CC
cord-293938-40zyv1h8	221	2	IFN	IFN	NNP
cord-293938-40zyv1h8	221	3	-	-	HYPH
cord-293938-40zyv1h8	221	4	beta1a	beta1a	NNP
cord-293938-40zyv1h8	221	5	in	in	IN
cord-293938-40zyv1h8	221	6	combination	combination	NN
cord-293938-40zyv1h8	221	7	with	with	IN
cord-293938-40zyv1h8	221	8	ribavirin	ribavirin	NN
cord-293938-40zyv1h8	221	9	to	to	TO
cord-293938-40zyv1h8	221	10	treat	treat	VB
cord-293938-40zyv1h8	221	11	Middle	Middle	NNP
cord-293938-40zyv1h8	221	12	East	East	NNP
cord-293938-40zyv1h8	221	13	respiratory	respiratory	JJ
cord-293938-40zyv1h8	221	14	syndrome	syndrome	NN
cord-293938-40zyv1h8	221	15	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	221	16	pneumonia	pneumonia	NN
cord-293938-40zyv1h8	221	17	:	:	:
cord-293938-40zyv1h8	222	1	a	a	DT
cord-293938-40zyv1h8	222	2	retrospective	retrospective	JJ
cord-293938-40zyv1h8	222	3	study	study	NN
cord-293938-40zyv1h8	222	4	Simultaneous	simultaneous	JJ
cord-293938-40zyv1h8	222	5	treatment	treatment	NN
cord-293938-40zyv1h8	222	6	of	of	IN
cord-293938-40zyv1h8	222	7	human	human	JJ
cord-293938-40zyv1h8	222	8	bronchial	bronchial	JJ
cord-293938-40zyv1h8	222	9	epithelial	epithelial	JJ
cord-293938-40zyv1h8	222	10	cells	cell	NNS
cord-293938-40zyv1h8	222	11	with	with	IN
cord-293938-40zyv1h8	222	12	serine	serine	NN
cord-293938-40zyv1h8	222	13	and	and	CC
cord-293938-40zyv1h8	222	14	cysteine	cysteine	NN
cord-293938-40zyv1h8	222	15	protease	protease	NN
cord-293938-40zyv1h8	222	16	inhibitors	inhibitor	NNS
cord-293938-40zyv1h8	222	17	prevents	prevent	VBZ
cord-293938-40zyv1h8	222	18	severe	severe	JJ
cord-293938-40zyv1h8	222	19	acute	acute	JJ
cord-293938-40zyv1h8	222	20	respiratory	respiratory	JJ
cord-293938-40zyv1h8	222	21	syndrome	syndrome	NN
cord-293938-40zyv1h8	222	22	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	222	23	entry	entry	NN
cord-293938-40zyv1h8	222	24	Proteolytic	Proteolytic	NNP
cord-293938-40zyv1h8	222	25	activation	activation	NN
cord-293938-40zyv1h8	222	26	of	of	IN
cord-293938-40zyv1h8	222	27	the	the	DT
cord-293938-40zyv1h8	222	28	SARS	SARS	NNP
cord-293938-40zyv1h8	222	29	-	-	HYPH
cord-293938-40zyv1h8	222	30	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	222	31	spike	spike	NN
cord-293938-40zyv1h8	222	32	protein	protein	NN
cord-293938-40zyv1h8	222	33	:	:	:
cord-293938-40zyv1h8	222	34	cutting	cut	VBG
cord-293938-40zyv1h8	222	35	enzymes	enzyme	NNS
cord-293938-40zyv1h8	222	36	at	at	IN
cord-293938-40zyv1h8	222	37	the	the	DT
cord-293938-40zyv1h8	222	38	cutting	cutting	JJ
cord-293938-40zyv1h8	222	39	edge	edge	NN
cord-293938-40zyv1h8	222	40	of	of	IN
cord-293938-40zyv1h8	222	41	antiviral	antiviral	JJ
cord-293938-40zyv1h8	222	42	research	research	NN
cord-293938-40zyv1h8	223	1	The	the	DT
cord-293938-40zyv1h8	223	2	SARS	SARS	NNP
cord-293938-40zyv1h8	223	3	-	-	HYPH
cord-293938-40zyv1h8	223	4	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	223	5	papain	papain	NN
cord-293938-40zyv1h8	223	6	-	-	HYPH
cord-293938-40zyv1h8	223	7	like	like	JJ
cord-293938-40zyv1h8	223	8	protease	protease	NN
cord-293938-40zyv1h8	223	9	:	:	:
cord-293938-40zyv1h8	223	10	structure	structure	NN
cord-293938-40zyv1h8	223	11	,	,	,
cord-293938-40zyv1h8	223	12	function	function	NN
cord-293938-40zyv1h8	223	13	and	and	CC
cord-293938-40zyv1h8	223	14	inhibition	inhibition	NN
cord-293938-40zyv1h8	223	15	by	by	IN
cord-293938-40zyv1h8	223	16	designed	design	VBN
cord-293938-40zyv1h8	223	17	antiviral	antiviral	JJ
cord-293938-40zyv1h8	223	18	compounds	compound	NNS
cord-293938-40zyv1h8	224	1	The	the	DT
cord-293938-40zyv1h8	224	2	SARS	SARS	NNP
cord-293938-40zyv1h8	224	3	-	-	HYPH
cord-293938-40zyv1h8	224	4	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	224	5	-	-	HYPH
cord-293938-40zyv1h8	224	6	host	host	NN
cord-293938-40zyv1h8	224	7	interactome	interactome	NNP
cord-293938-40zyv1h8	224	8	:	:	:
cord-293938-40zyv1h8	225	1	identification	identification	NN
cord-293938-40zyv1h8	225	2	of	of	IN
cord-293938-40zyv1h8	225	3	cyclophilins	cyclophilins	NNP
cord-293938-40zyv1h8	225	4	as	as	IN
cord-293938-40zyv1h8	225	5	target	target	NN
cord-293938-40zyv1h8	225	6	for	for	IN
cord-293938-40zyv1h8	225	7	pan	pan	NN
cord-293938-40zyv1h8	225	8	-	-	JJ
cord-293938-40zyv1h8	225	9	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	225	10	inhibitors	inhibitor	NNS
cord-293938-40zyv1h8	225	11	Targeting	target	VBG
cord-293938-40zyv1h8	225	12	membrane	membrane	NN
cord-293938-40zyv1h8	225	13	-	-	HYPH
cord-293938-40zyv1h8	225	14	bound	bind	VBN
cord-293938-40zyv1h8	225	15	viral	viral	JJ
cord-293938-40zyv1h8	225	16	RNA	RNA	NNP
cord-293938-40zyv1h8	225	17	synthesis	synthesis	NN
cord-293938-40zyv1h8	225	18	reveals	reveal	VBZ
cord-293938-40zyv1h8	225	19	potent	potent	JJ
cord-293938-40zyv1h8	225	20	inhibition	inhibition	NN
cord-293938-40zyv1h8	225	21	of	of	IN
cord-293938-40zyv1h8	225	22	diverse	diverse	JJ
cord-293938-40zyv1h8	225	23	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	225	24	including	include	VBG
cord-293938-40zyv1h8	225	25	the	the	DT
cord-293938-40zyv1h8	225	26	Middle	Middle	NNP
cord-293938-40zyv1h8	225	27	East	East	NNP
cord-293938-40zyv1h8	225	28	respiratory	respiratory	JJ
cord-293938-40zyv1h8	225	29	syndrome	syndrome	NN
cord-293938-40zyv1h8	225	30	virus	virus	NN
cord-293938-40zyv1h8	225	31	Novel	Novel	NNP
cord-293938-40zyv1h8	225	32	polymeric	polymeric	JJ
cord-293938-40zyv1h8	225	33	inhibitors	inhibitor	NNS
cord-293938-40zyv1h8	225	34	of	of	IN
cord-293938-40zyv1h8	225	35	HCoV	HCoV	NNP
cord-293938-40zyv1h8	225	36	-	-	HYPH
cord-293938-40zyv1h8	225	37	NL63	NL63	NNP
cord-293938-40zyv1h8	225	38	Isolation	Isolation	NNP
cord-293938-40zyv1h8	225	39	from	from	IN
cord-293938-40zyv1h8	225	40	man	man	NN
cord-293938-40zyv1h8	225	41	of	of	IN
cord-293938-40zyv1h8	225	42	"	"	``
cord-293938-40zyv1h8	225	43	avian	avian	JJ
cord-293938-40zyv1h8	225	44	infectious	infectious	JJ
cord-293938-40zyv1h8	225	45	bronchitis	bronchitis	NN
cord-293938-40zyv1h8	225	46	virus	virus	NN
cord-293938-40zyv1h8	225	47	-	-	:
cord-293938-40zyv1h8	225	48	like	like	JJ
cord-293938-40zyv1h8	225	49	"	"	``
cord-293938-40zyv1h8	225	50	viruses	virus	NNS
cord-293938-40zyv1h8	225	51	(	(	-LRB-
cord-293938-40zyv1h8	225	52	coronaviruses	coronaviruse	NNS
cord-293938-40zyv1h8	225	53	)	)	-RRB-
cord-293938-40zyv1h8	225	54	similar	similar	JJ
cord-293938-40zyv1h8	225	55	to	to	IN
cord-293938-40zyv1h8	225	56	229E	229e	CD
cord-293938-40zyv1h8	225	57	virus	virus	NN
cord-293938-40zyv1h8	225	58	,	,	,
cord-293938-40zyv1h8	225	59	with	with	IN
cord-293938-40zyv1h8	225	60	some	some	DT
cord-293938-40zyv1h8	225	61	epidemiological	epidemiological	JJ
cord-293938-40zyv1h8	225	62	observations	observation	NNS
cord-293938-40zyv1h8	225	63	Human	human	JJ
cord-293938-40zyv1h8	225	64	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	225	65	229E	229e	CD
cord-293938-40zyv1h8	225	66	:	:	:
cord-293938-40zyv1h8	226	1	receptor	receptor	NN
cord-293938-40zyv1h8	226	2	binding	bind	VBG
cord-293938-40zyv1h8	226	3	domain	domain	NN
cord-293938-40zyv1h8	226	4	and	and	CC
cord-293938-40zyv1h8	226	5	neutralization	neutralization	NN
cord-293938-40zyv1h8	226	6	by	by	IN
cord-293938-40zyv1h8	226	7	soluble	soluble	JJ
cord-293938-40zyv1h8	226	8	receptor	receptor	NN
cord-293938-40zyv1h8	226	9	at	at	IN
cord-293938-40zyv1h8	226	10	37	37	CD
cord-293938-40zyv1h8	226	11	degrees	degree	NNS
cord-293938-40zyv1h8	226	12	C	c	NN
cord-293938-40zyv1h8	226	13	Growth	growth	NN
cord-293938-40zyv1h8	226	14	in	in	IN
cord-293938-40zyv1h8	226	15	suckling	suckle	VBG
cord-293938-40zyv1h8	226	16	-	-	HYPH
cord-293938-40zyv1h8	226	17	mouse	mouse	NN
cord-293938-40zyv1h8	226	18	brain	brain	NN
cord-293938-40zyv1h8	226	19	of	of	IN
cord-293938-40zyv1h8	226	20	"	"	``
cord-293938-40zyv1h8	226	21	IBV	IBV	NNP
cord-293938-40zyv1h8	226	22	-	-	HYPH
cord-293938-40zyv1h8	226	23	like	like	JJ
cord-293938-40zyv1h8	226	24	"	"	''
cord-293938-40zyv1h8	226	25	viruses	virus	NNS
cord-293938-40zyv1h8	226	26	from	from	IN
cord-293938-40zyv1h8	226	27	patients	patient	NNS
cord-293938-40zyv1h8	226	28	with	with	IN
cord-293938-40zyv1h8	226	29	upper	upper	JJ
cord-293938-40zyv1h8	226	30	respiratory	respiratory	JJ
cord-293938-40zyv1h8	226	31	tract	tract	NN
cord-293938-40zyv1h8	226	32	disease	disease	NN
cord-293938-40zyv1h8	227	1	The	the	DT
cord-293938-40zyv1h8	227	2	SARS	SARS	NNP
cord-293938-40zyv1h8	227	3	-	-	HYPH
cord-293938-40zyv1h8	227	4	CoV	CoV	NNP
cord-293938-40zyv1h8	227	5	S	S	NNP
cord-293938-40zyv1h8	227	6	glycoprotein	glycoprotein	NN
cord-293938-40zyv1h8	227	7	:	:	:
cord-293938-40zyv1h8	227	8	expression	expression	NN
cord-293938-40zyv1h8	227	9	and	and	CC
cord-293938-40zyv1h8	227	10	functional	functional	JJ
cord-293938-40zyv1h8	227	11	characterization	characterization	NN
cord-293938-40zyv1h8	227	12	Identification	identification	NN
cord-293938-40zyv1h8	227	13	of	of	IN
cord-293938-40zyv1h8	227	14	residues	residue	NNS
cord-293938-40zyv1h8	227	15	in	in	IN
cord-293938-40zyv1h8	227	16	the	the	DT
cord-293938-40zyv1h8	227	17	receptor	receptor	NN
cord-293938-40zyv1h8	227	18	-	-	HYPH
cord-293938-40zyv1h8	227	19	binding	bind	VBG
cord-293938-40zyv1h8	227	20	domain	domain	NN
cord-293938-40zyv1h8	227	21	(	(	-LRB-
cord-293938-40zyv1h8	227	22	RBD	RBD	NNP
cord-293938-40zyv1h8	227	23	)	)	-RRB-
cord-293938-40zyv1h8	227	24	of	of	IN
cord-293938-40zyv1h8	227	25	the	the	DT
cord-293938-40zyv1h8	227	26	spike	spike	NN
cord-293938-40zyv1h8	227	27	protein	protein	NN
cord-293938-40zyv1h8	227	28	of	of	IN
cord-293938-40zyv1h8	227	29	human	human	JJ
cord-293938-40zyv1h8	227	30	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	228	1	NL63	NL63	NNP
cord-293938-40zyv1h8	229	1	that	that	WDT
cord-293938-40zyv1h8	229	2	are	be	VBP
cord-293938-40zyv1h8	229	3	critical	critical	JJ
cord-293938-40zyv1h8	229	4	for	for	IN
cord-293938-40zyv1h8	229	5	the	the	DT
cord-293938-40zyv1h8	229	6	RBD	RBD	NNP
cord-293938-40zyv1h8	229	7	-	-	HYPH
cord-293938-40zyv1h8	229	8	ACE2	ACE2	NNP
cord-293938-40zyv1h8	229	9	receptor	receptor	NN
cord-293938-40zyv1h8	229	10	interaction	interaction	NN
cord-293938-40zyv1h8	229	11	The	the	DT
cord-293938-40zyv1h8	229	12	receptor	receptor	NN
cord-293938-40zyv1h8	229	13	binding	bind	VBG
cord-293938-40zyv1h8	229	14	domain	domain	NN
cord-293938-40zyv1h8	229	15	of	of	IN
cord-293938-40zyv1h8	229	16	the	the	DT
cord-293938-40zyv1h8	229	17	new	new	JJ
cord-293938-40zyv1h8	229	18	Middle	Middle	NNP
cord-293938-40zyv1h8	229	19	East	East	NNP
cord-293938-40zyv1h8	229	20	respiratory	respiratory	JJ
cord-293938-40zyv1h8	229	21	syndrome	syndrome	NN
cord-293938-40zyv1h8	229	22	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	229	23	maps	map	VBZ
cord-293938-40zyv1h8	229	24	to	to	IN
cord-293938-40zyv1h8	229	25	a	a	DT
cord-293938-40zyv1h8	229	26	231-residue	231-residue	CD
cord-293938-40zyv1h8	229	27	region	region	NN
cord-293938-40zyv1h8	229	28	in	in	IN
cord-293938-40zyv1h8	229	29	the	the	DT
cord-293938-40zyv1h8	229	30	spike	spike	NN
cord-293938-40zyv1h8	229	31	protein	protein	NN
cord-293938-40zyv1h8	229	32	that	that	WDT
cord-293938-40zyv1h8	229	33	efficiently	efficiently	RB
cord-293938-40zyv1h8	229	34	elicits	elicit	VBZ
cord-293938-40zyv1h8	229	35	neutralizing	neutralize	VBG
cord-293938-40zyv1h8	229	36	antibodies	antibody	NNS
cord-293938-40zyv1h8	229	37	SARS	SARS	NNP
cord-293938-40zyv1h8	229	38	-	-	HYPH
cord-293938-40zyv1h8	229	39	CoV	cov	NN
cord-293938-40zyv1h8	229	40	replication	replication	NN
cord-293938-40zyv1h8	229	41	and	and	CC
cord-293938-40zyv1h8	229	42	pathogenesis	pathogenesis	NN
cord-293938-40zyv1h8	229	43	in	in	IN
cord-293938-40zyv1h8	229	44	an	an	DT
cord-293938-40zyv1h8	229	45	in	in	FW
cord-293938-40zyv1h8	229	46	vitro	vitro	FW
cord-293938-40zyv1h8	229	47	model	model	NN
cord-293938-40zyv1h8	229	48	of	of	IN
cord-293938-40zyv1h8	229	49	the	the	DT
cord-293938-40zyv1h8	229	50	human	human	JJ
cord-293938-40zyv1h8	229	51	conducting	conduct	VBG
cord-293938-40zyv1h8	229	52	airway	airway	NN
cord-293938-40zyv1h8	229	53	epithelium	epithelium	NN
cord-293938-40zyv1h8	229	54	Cell	Cell	NNP
cord-293938-40zyv1h8	229	55	host	host	NN
cord-293938-40zyv1h8	229	56	response	response	NN
cord-293938-40zyv1h8	229	57	to	to	IN
cord-293938-40zyv1h8	229	58	infection	infection	NN
cord-293938-40zyv1h8	229	59	with	with	IN
cord-293938-40zyv1h8	229	60	novel	novel	JJ
cord-293938-40zyv1h8	229	61	human	human	JJ
cord-293938-40zyv1h8	229	62	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	229	63	EMC	EMC	NNP
cord-293938-40zyv1h8	229	64	predicts	predict	VBZ
cord-293938-40zyv1h8	229	65	potential	potential	JJ
cord-293938-40zyv1h8	229	66	antivirals	antiviral	NNS
cord-293938-40zyv1h8	229	67	and	and	CC
cord-293938-40zyv1h8	229	68	important	important	JJ
cord-293938-40zyv1h8	229	69	differences	difference	NNS
cord-293938-40zyv1h8	229	70	with	with	IN
cord-293938-40zyv1h8	229	71	SARS	SARS	NNP
cord-293938-40zyv1h8	229	72	coronavirus	coronavirus	NN
cord-293938-40zyv1h8	229	73	Dipeptidyl	Dipeptidyl	NNP
cord-293938-40zyv1h8	229	74	peptidase	peptidase	NN
cord-293938-40zyv1h8	229	75	4	4	CD
cord-293938-40zyv1h8	229	76	distribution	distribution	NN
cord-293938-40zyv1h8	229	77	in	in	IN
cord-293938-40zyv1h8	229	78	the	the	DT
cord-293938-40zyv1h8	229	79	human	human	JJ
cord-293938-40zyv1h8	229	80	respiratory	respiratory	JJ
cord-293938-40zyv1h8	229	81	tract	tract	NN
cord-293938-40zyv1h8	229	82	:	:	:
cord-293938-40zyv1h8	229	83	implications	implication	NNS
cord-293938-40zyv1h8	229	84	for	for	IN
cord-293938-40zyv1h8	229	85	the	the	DT
cord-293938-40zyv1h8	229	86	Middle	Middle	NNP
cord-293938-40zyv1h8	229	87	East	East	NNP
cord-293938-40zyv1h8	229	88	respiratory	respiratory	JJ
cord-293938-40zyv1h8	229	89	syndrome	syndrome	NN
cord-293938-40zyv1h8	230	1	We	-PRON-	PRP
cord-293938-40zyv1h8	230	2	would	would	MD
cord-293938-40zyv1h8	230	3	like	like	VB
cord-293938-40zyv1h8	230	4	to	to	TO
cord-293938-40zyv1h8	230	5	thank	thank	VB
cord-293938-40zyv1h8	230	6	Prof.	Prof.	NNP
cord-293938-40zyv1h8	230	7	Dr.	Dr.	NNP
cord-293938-40zyv1h8	230	8	Volker	Volker	NNP
cord-293938-40zyv1h8	230	9	Thiel	Thiel	NNP
cord-293938-40zyv1h8	230	10	for	for	IN
cord-293938-40zyv1h8	230	11	his	-PRON-	PRP$
cord-293938-40zyv1h8	230	12	careful	careful	JJ
cord-293938-40zyv1h8	230	13	review	review	NN
cord-293938-40zyv1h8	230	14	of	of	IN
cord-293938-40zyv1h8	230	15	the	the	DT
cord-293938-40zyv1h8	230	16	manuscript	manuscript	NN
cord-293938-40zyv1h8	230	17	and	and	CC
cord-293938-40zyv1h8	230	18	Dr.	Dr.	NNP
cord-293938-40zyv1h8	230	19	Eveline	Eveline	NNP
cord-293938-40zyv1h8	230	20	Kindler	Kindler	NNP
cord-293938-40zyv1h8	230	21	for	for	IN
cord-293938-40zyv1h8	230	22	providing	provide	VBG
cord-293938-40zyv1h8	230	23	components	component	NNS
cord-293938-40zyv1h8	230	24	for	for	IN
cord-293938-40zyv1h8	230	25	figures	figure	NNS
cord-293938-40zyv1h8	230	26	.	.	.
cord-293938-40zyv1h8	231	1	•	•	NNP
cord-293938-40zyv1h8	232	1	We	-PRON-	PRP
cord-293938-40zyv1h8	232	2	accept	accept	VBP
cord-293938-40zyv1h8	232	3	pre	pre	JJ
cord-293938-40zyv1h8	232	4	-	-	JJ
cord-293938-40zyv1h8	232	5	submission	submission	JJ
cord-293938-40zyv1h8	232	6	inquiries	inquiry	NNS
cord-293938-40zyv1h8	233	1	•	•	NNP
cord-293938-40zyv1h8	234	1	Our	-PRON-	PRP$
cord-293938-40zyv1h8	234	2	selector	selector	NN
cord-293938-40zyv1h8	234	3	tool	tool	NN
cord-293938-40zyv1h8	234	4	helps	help	VBZ
cord-293938-40zyv1h8	234	5	you	-PRON-	PRP
cord-293938-40zyv1h8	234	6	to	to	TO
cord-293938-40zyv1h8	234	7	find	find	VB
cord-293938-40zyv1h8	234	8	the	the	DT
cord-293938-40zyv1h8	234	9	most	most	RBS
cord-293938-40zyv1h8	234	10	relevant	relevant	JJ
cord-293938-40zyv1h8	234	11	journal	journal	NN
cord-293938-40zyv1h8	234	12	Submit	submit	VB
cord-293938-40zyv1h8	234	13	your	-PRON-	PRP$
cord-293938-40zyv1h8	234	14	next	next	JJ
cord-293938-40zyv1h8	234	15	manuscript	manuscript	NN
cord-293938-40zyv1h8	234	16	to	to	IN
cord-293938-40zyv1h8	234	17	BioMed	BioMed	NNP
cord-293938-40zyv1h8	234	18	Central	Central	NNP
cord-293938-40zyv1h8	234	19	and	and	CC
cord-293938-40zyv1h8	234	20	we	-PRON-	PRP
cord-293938-40zyv1h8	234	21	will	will	MD
cord-293938-40zyv1h8	234	22	help	help	VB
cord-293938-40zyv1h8	234	23	you	-PRON-	PRP
cord-293938-40zyv1h8	234	24	at	at	IN
cord-293938-40zyv1h8	234	25	every	every	DT
cord-293938-40zyv1h8	234	26	step	step	NN
cord-293938-40zyv1h8	234	27	:	:	: