id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-307364-j86t65qu	Uccellini, Lorenzo	Identification of a novel nidovirus in an outbreak of fatal respiratory disease in ball pythons (Python regius)	2014-08-08		.txt	text/plain	1917	110	45	In situ hybridization confirmed the presence of intracellular, intracytoplasmic viral nucleic acids in the lungs of infected snakes. Phylogenetic analysis based on a 1,136 amino acid segment of the polyprotein suggests that this virus may represent a new species in the subfamily Torovirinae. CONCLUSIONS: This report of a novel nidovirus in ball pythons may provide insight into the pathogenesis of respiratory disease in this species and enhances our knowledge of the diversity of nidoviruses. Here we report the discovery of a novel nidovirus in a collection of ball pythons (Python regius) in upstate New York with pneumonia, tracheitis and esophagitis. Based on the phylogenetic position and the genetic distances between In situ hybridization to a 934 nt fragment of the genomic polyprotein 1ab region was used to assess viral infection and distribution in the lung tissue. Identification of a novel nidovirus in an outbreak of fatal respiratory disease in ball pythons (Python regius)	./cache/cord-307364-j86t65qu.txt	./txt/cord-307364-j86t65qu.txt