id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-292581-6ipzvryb	Alagarasu, Kalichamy	Elevated levels of vitamin D and deficiency of mannose binding lectin in dengue hemorrhagic fever	2012-05-04		.txt	text/plain	3742	208	51	BACKGROUND: Altered plasma concentrations of vitamin D and mannose binding lectin (MBL), components of innate immunity, have been shown to be associated with the pathogenesis of viral infections. The objective of the present study was to find out whether plasma concentrations of MBL and vitamin D are different in patients with dengue fever (DF) and dengue hemorrhagic fever (DHF). Therefore, we investigated the levels of plasma vitamin D and MBL in dengue infected patients in the context of disease severity and immune status. When the patients were grouped based on immune status and disease severity, secondary DHF cases had significantly higher concentrations of vitamin D as compared to secondary DF cases (P < 0.050). Analysis of circulating concentrations of MBL in dengue cases and healthy controls revealed no significant difference between the two groups suggesting that the MBL mediated pathway of complement activation might be inhibited or may not be induced during DENV infection.	./cache/cord-292581-6ipzvryb.txt	./txt/cord-292581-6ipzvryb.txt