id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-262904-0b0ljjq1	Lon, Jerome Rumdon	Prediction and evolution of B cell epitopes of surface protein in SARS-CoV-2	2020-10-29		.txt	text/plain	5006	263	53	It is worth mentioning that all 6 identified epitopes were conserved in nearly 3500 SARS-CoV-2 genomes, showing that it is helpful to obtain stable and long-acting epitopes under the condition of high frequency of amino acid mutation, which deserved further study at the experiment level. On this basis, we predicted the linear and conformational B cell epitopes, analyzed the conservation of the epitopes, the adaptability and other evolutionary characteristics of the surface protein, which provided a theoretical basis for the vaccine development and prevention of SARS-CoV-2. With the amino acid sequences of the surface protein of SARS-CoV-2 of NC_045512.2 as templates, we predicted the 3D structure of E and M protein through the online server SWISS-MODEL [10] based on homology modeling method, selected the optimal structure based on the template identity and GMQE value [10] , and the rationality of the structure was evaluated by Ramachandran plot [11] with PDBsum server.	./cache/cord-262904-0b0ljjq1.txt	./txt/cord-262904-0b0ljjq1.txt