id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-258935-tatae3hs	Lin, Wenyao	A baculovirus dual expression system-based vaccine confers complete protection against lethal challenge with H9N2 avian influenza virus in mice	2011-06-04		.txt	text/plain	3590	165	45	title: A baculovirus dual expression system-based vaccine confers complete protection against lethal challenge with H9N2 avian influenza virus in mice To evaluate the potency of the recombinant baculovirus BV-Dual-HA against lethal influenza virus challenge, the immunized mice were challenged with 50 MLD 50 of H9N2 V strain on day 42. Most mice vaccinated with pc-HA, AcMNPV-WT, or PBS had detectable lung virus titers A B Figure 3 Antibody responses in immunized mice with BV-Dual-HA. From these results, it is obvious that immunization with BV-Dual-HA can induce a robust antibody response and confer complete protection against lethal virus challenge in a mouse model, indicating that BV-Dual-HA is potential candidate vaccine that can prevent and control the pandemic spread of the H9N2 influenza virus. Baculovirus induces an innate immune response and confers protection from lethal influenza virus infection in mice A pseudotype baculovirus-mediated vaccine confers protective immunity against lethal challenge with H5N1 avian influenza virus in mice and chickens	./cache/cord-258935-tatae3hs.txt	./txt/cord-258935-tatae3hs.txt