id author title date pages extension mime words sentences flesch summary cache txt cord-354114-frdsct44 Vogel, Liesbeth Pathogenic characteristics of persistent feline enteric coronavirus infection in cats 2010-07-23 .txt text/plain 5339 266 53 FECV is associated with asymptomatic persistent enteric infections, while FIPV causes feline infectious peritonitis (FIP), a usually fatal systemic disease in domestic cats and some wild Felidae. Faecal virus, i.e. genomic RNA, was detected during persistent FECV infection only in the large intestine, downstream of the appendix, and could occasionally be observed also in the blood. The cats were monitored for clinical signs, body weight, faecal virus shedding and serum antibody titres for 70 days post inoculation. In all animals, the amount of virus in the faeces subsequently increased within two days to peak levels of 10 6 -10 8 genomes/lL faeces, after which shedding remained high for an extended period until day 16 and day 23 post inoculation in FECV UCD and FECV RM infected cats, respectively. In order to determine in which part(s) of the gut virus was present during viral persistence, we screened the contents of the entire intestines of two FECV UCD infected cats. ./cache/cord-354114-frdsct44.txt ./txt/cord-354114-frdsct44.txt