id author title date pages extension mime words sentences flesch summary cache txt cord-269531-7gy4epzo Kumar, Pankaj Proteomic analysis of purified turkey adenovirus 3 virions 2015-07-09 .txt text/plain 4332 270 40 To develop a better understanding of virus-host interactions, we performed a comprehensive proteomic analysis of proteinase K treated purified TAdV-3 virions isolated from spleens of infected turkeys, by utilizing one-dimensional liquid chromatography mass spectrometry. The LC-MS/MS analysis of proteinase K treated CsCl 2 density gradient purified TAdV-3 virions identified eleven virus-encoded proteins (hexon, pVI, pVII, penton base, pVIII, sialidase, IIIA, adenain, pX, IVa2 and DBP) previously reported to be in other adenoviruses (Table 3 and Figure 3A ) [16] . In addition, five host proteins namely, vitronectin, collagen alpha-3 (VI) chain, collagen alpha-2 (VI) chain, tyrosine protein phosphatase and turkey heterophil peptide 2 (THP-2) were only detected in proteinase K treated TAdV-3 virions. The proteomic analysis of proteinase K treated purified virions identified eleven cellular proteins incorporated in TAdV-3, which have been identified in other viruses (Table 4 ). In addition, proteomic analysis identified seven host proteins incorporated in TAdV-3 virions (Table 4) , which have not been identified so far in any other virus. ./cache/cord-269531-7gy4epzo.txt ./txt/cord-269531-7gy4epzo.txt