id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-003506-ztqjo13e	Feng, Min	A balanced game: chicken macrophage response to ALV-J infection	2019-03-06		.txt	text/plain	5674	333	50	ALV-J infection induced strong innate immune responses in chicken MDM at 3 hpi, instead of 36 hpi, according to the analysis results of Gene Ontology and KEGG pathway. In our previous study, we found that primary chicken monocyte-derived macrophages (MDM) were susceptible to ALV-J and infection resulted in expression of immune-related genes [10] . In this study, RNA-seq analysis platform and gene overexpression verification were employed to analyze chicken MDM gene expression after ALV-J infection. According to published studies [21] [22] [23] , 94 and 23 differentially expressed interferon-stimulated genes (ISG) were identified in ALV-J-infected MDM at 3 hpi and 36 hpi, respectively (Additional file 6). Overexpression of CISH, EX-FABP and SOCS3 significantly increased the expression of ALV-J env gene at protein levels ( Figures 8A and B) and mRNA levels ( Figure 8C ) in chicken MDM cells at 3 hpi.	./cache/cord-003506-ztqjo13e.txt	./txt/cord-003506-ztqjo13e.txt