id	sid	tid	token	lemma	pos
cord-312119-wzcas4zd	1	1	key	key	NN
cord-312119-wzcas4zd	1	2	:	:	:
cord-312119-wzcas4zd	1	3	cord-312119-wzcas4zd	cord-312119-wzcas4zd	.
cord-312119-wzcas4zd	2	1	authors	author	NNS
cord-312119-wzcas4zd	2	2	:	:	:
cord-312119-wzcas4zd	2	3	Lu	Lu	NNP
cord-312119-wzcas4zd	2	4	,	,	,
cord-312119-wzcas4zd	2	5	Ti	Ti	NNP
cord-312119-wzcas4zd	2	6	;	;	:
cord-312119-wzcas4zd	2	7	Seo	Seo	NNP
cord-312119-wzcas4zd	2	8	,	,	,
cord-312119-wzcas4zd	2	9	Hyesuk	Hyesuk	NNP
cord-312119-wzcas4zd	2	10	;	;	:
cord-312119-wzcas4zd	2	11	Moxley	Moxley	NNP
cord-312119-wzcas4zd	2	12	,	,	,
cord-312119-wzcas4zd	2	13	Rodney	Rodney	NNP
cord-312119-wzcas4zd	2	14	A.	A.	NNP
cord-312119-wzcas4zd	2	15	;	;	:
cord-312119-wzcas4zd	2	16	Zhang	Zhang	NNP
cord-312119-wzcas4zd	2	17	,	,	,
cord-312119-wzcas4zd	3	1	Weiping	Weiping	NNP
cord-312119-wzcas4zd	3	2	title	title	NN
cord-312119-wzcas4zd	3	3	:	:	:
cord-312119-wzcas4zd	3	4	Mapping	map	VBG
cord-312119-wzcas4zd	3	5	the	the	DT
cord-312119-wzcas4zd	3	6	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	3	7	epitopes	epitope	NNS
cord-312119-wzcas4zd	3	8	of	of	IN
cord-312119-wzcas4zd	3	9	F18	F18	NNP
cord-312119-wzcas4zd	3	10	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	3	11	adhesin	adhesin	NN
cord-312119-wzcas4zd	3	12	subunit	subunit	NN
cord-312119-wzcas4zd	3	13	FedF	FedF	NNP
cord-312119-wzcas4zd	3	14	of	of	IN
cord-312119-wzcas4zd	3	15	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	3	16	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	3	17	coli	coli	NNS
cord-312119-wzcas4zd	3	18	(	(	-LRB-
cord-312119-wzcas4zd	3	19	ETEC	ETEC	NNP
cord-312119-wzcas4zd	3	20	)	)	-RRB-
cord-312119-wzcas4zd	3	21	date	date	NN
cord-312119-wzcas4zd	3	22	:	:	:
cord-312119-wzcas4zd	3	23	2019	2019	CD
cord-312119-wzcas4zd	3	24	-	-	HYPH
cord-312119-wzcas4zd	3	25	02	02	CD
cord-312119-wzcas4zd	3	26	-	-	HYPH
cord-312119-wzcas4zd	3	27	06	06	CD
cord-312119-wzcas4zd	3	28	journal	journal	NN
cord-312119-wzcas4zd	3	29	:	:	:
cord-312119-wzcas4zd	4	1	Vet	Vet	NNP
cord-312119-wzcas4zd	4	2	Microbiol	Microbiol	NNP
cord-312119-wzcas4zd	4	3	DOI	DOI	NNP
cord-312119-wzcas4zd	4	4	:	:	:
cord-312119-wzcas4zd	4	5	10.1016	10.1016	CD
cord-312119-wzcas4zd	4	6	/	/	SYM
cord-312119-wzcas4zd	4	7	j.vetmic.2019.02.015	j.vetmic.2019.02.015	CD
cord-312119-wzcas4zd	4	8	sha	sha	NNP
cord-312119-wzcas4zd	4	9	:	:	:
cord-312119-wzcas4zd	4	10	20e79fc5f7893e8decf5f86711ab3ea1802346e2	20e79fc5f7893e8decf5f86711ab3ea1802346e2	CD
cord-312119-wzcas4zd	4	11	doc_id	doc_id	CD
cord-312119-wzcas4zd	4	12	:	:	:
cord-312119-wzcas4zd	4	13	312119	312119	CD
cord-312119-wzcas4zd	4	14	cord_uid	cord_uid	NNS
cord-312119-wzcas4zd	4	15	:	:	:
cord-312119-wzcas4zd	4	16	wzcas4zd	wzcas4zd	NNP
cord-312119-wzcas4zd	4	17	K88	K88	NNP
cord-312119-wzcas4zd	4	18	and	and	CC
cord-312119-wzcas4zd	4	19	F18	F18	NNP
cord-312119-wzcas4zd	4	20	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	4	21	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	4	22	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	4	23	coli	coli	NNS
cord-312119-wzcas4zd	4	24	(	(	-LRB-
cord-312119-wzcas4zd	4	25	ETEC	ETEC	NNP
cord-312119-wzcas4zd	4	26	)	)	-RRB-
cord-312119-wzcas4zd	5	1	are	be	VBP
cord-312119-wzcas4zd	5	2	the	the	DT
cord-312119-wzcas4zd	5	3	major	major	JJ
cord-312119-wzcas4zd	5	4	causes	cause	NNS
cord-312119-wzcas4zd	5	5	of	of	IN
cord-312119-wzcas4zd	5	6	post	post	JJ
cord-312119-wzcas4zd	5	7	-	-	JJ
cord-312119-wzcas4zd	5	8	weaning	weaning	JJ
cord-312119-wzcas4zd	5	9	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	5	10	(	(	-LRB-
cord-312119-wzcas4zd	5	11	PWD	pwd	NN
cord-312119-wzcas4zd	5	12	)	)	-RRB-
cord-312119-wzcas4zd	5	13	in	in	IN
cord-312119-wzcas4zd	5	14	pigs	pig	NNS
cord-312119-wzcas4zd	5	15	.	.	.
cord-312119-wzcas4zd	6	1	A	a	DT
cord-312119-wzcas4zd	6	2	vaccine	vaccine	NN
cord-312119-wzcas4zd	6	3	that	that	WDT
cord-312119-wzcas4zd	6	4	induces	induce	VBZ
cord-312119-wzcas4zd	6	5	broad	broad	JJ
cord-312119-wzcas4zd	6	6	immunity	immunity	NN
cord-312119-wzcas4zd	6	7	to	to	TO
cord-312119-wzcas4zd	6	8	prevent	prevent	VB
cord-312119-wzcas4zd	6	9	K88	K88	NNP
cord-312119-wzcas4zd	6	10	and	and	CC
cord-312119-wzcas4zd	6	11	F18	f18	JJ
cord-312119-wzcas4zd	6	12	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	6	13	ETEC	etec	JJ
cord-312119-wzcas4zd	6	14	bacterial	bacterial	JJ
cord-312119-wzcas4zd	6	15	attachment	attachment	NN
cord-312119-wzcas4zd	6	16	and	and	CC
cord-312119-wzcas4zd	6	17	colonization	colonization	NN
cord-312119-wzcas4zd	6	18	in	in	IN
cord-312119-wzcas4zd	6	19	pig	pig	NN
cord-312119-wzcas4zd	6	20	small	small	JJ
cord-312119-wzcas4zd	6	21	intestines	intestine	NNS
cord-312119-wzcas4zd	6	22	and	and	CC
cord-312119-wzcas4zd	6	23	to	to	TO
cord-312119-wzcas4zd	6	24	neutralize	neutralize	VB
cord-312119-wzcas4zd	6	25	enterotoxin	enterotoxin	NNP
cord-312119-wzcas4zd	6	26	enterotoxicity	enterotoxicity	NN
cord-312119-wzcas4zd	6	27	would	would	MD
cord-312119-wzcas4zd	6	28	be	be	VB
cord-312119-wzcas4zd	6	29	effective	effective	JJ
cord-312119-wzcas4zd	6	30	for	for	IN
cord-312119-wzcas4zd	6	31	PWD	pwd	NN
cord-312119-wzcas4zd	6	32	.	.	.
cord-312119-wzcas4zd	7	1	Structure	structure	NN
cord-312119-wzcas4zd	7	2	-	-	HYPH
cord-312119-wzcas4zd	7	3	based	base	VBN
cord-312119-wzcas4zd	7	4	multiepitope	multiepitope	NN
cord-312119-wzcas4zd	7	5	-	-	HYPH
cord-312119-wzcas4zd	7	6	fusion	fusion	NN
cord-312119-wzcas4zd	7	7	-	-	HYPH
cord-312119-wzcas4zd	7	8	antigen	antigen	NN
cord-312119-wzcas4zd	7	9	(	(	-LRB-
cord-312119-wzcas4zd	7	10	MEFA	MEFA	NNP
cord-312119-wzcas4zd	7	11	)	)	-RRB-
cord-312119-wzcas4zd	7	12	technology	technology	NN
cord-312119-wzcas4zd	7	13	using	use	VBG
cord-312119-wzcas4zd	7	14	a	a	DT
cord-312119-wzcas4zd	7	15	backbone	backbone	NN
cord-312119-wzcas4zd	7	16	immunogen	immunogen	NN
cord-312119-wzcas4zd	7	17	to	to	TO
cord-312119-wzcas4zd	7	18	present	present	VB
cord-312119-wzcas4zd	7	19	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	7	20	epitopes	epitope	NNS
cord-312119-wzcas4zd	7	21	of	of	IN
cord-312119-wzcas4zd	7	22	representing	represent	VBG
cord-312119-wzcas4zd	7	23	virulence	virulence	NN
cord-312119-wzcas4zd	7	24	factors	factor	NNS
cord-312119-wzcas4zd	7	25	capacitates	capacitate	VBZ
cord-312119-wzcas4zd	7	26	development	development	NN
cord-312119-wzcas4zd	7	27	of	of	IN
cord-312119-wzcas4zd	7	28	broadly	broadly	RB
cord-312119-wzcas4zd	7	29	protective	protective	JJ
cord-312119-wzcas4zd	7	30	ETEC	etec	JJ
cord-312119-wzcas4zd	7	31	vaccines	vaccine	NNS
cord-312119-wzcas4zd	7	32	.	.	.
cord-312119-wzcas4zd	8	1	Neutralizing	neutralize	VBG
cord-312119-wzcas4zd	8	2	epitopes	epitope	NNS
cord-312119-wzcas4zd	8	3	have	have	VBP
cord-312119-wzcas4zd	8	4	been	be	VBN
cord-312119-wzcas4zd	8	5	identified	identify	VBN
cord-312119-wzcas4zd	8	6	from	from	IN
cord-312119-wzcas4zd	8	7	K88	K88	NNP
cord-312119-wzcas4zd	8	8	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	8	9	adhesin	adhesin	NN
cord-312119-wzcas4zd	8	10	(	(	-LRB-
cord-312119-wzcas4zd	8	11	FaeG	FaeG	NNP
cord-312119-wzcas4zd	8	12	)	)	-RRB-
cord-312119-wzcas4zd	8	13	and	and	CC
cord-312119-wzcas4zd	8	14	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	8	15	but	but	CC
cord-312119-wzcas4zd	8	16	not	not	RB
cord-312119-wzcas4zd	8	17	F18	F18	NNP
cord-312119-wzcas4zd	8	18	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	8	19	adhesin	adhesin	NN
cord-312119-wzcas4zd	8	20	.	.	.
cord-312119-wzcas4zd	9	1	In	in	IN
cord-312119-wzcas4zd	9	2	this	this	DT
cord-312119-wzcas4zd	9	3	study	study	NN
cord-312119-wzcas4zd	9	4	,	,	,
cord-312119-wzcas4zd	9	5	we	-PRON-	PRP
cord-312119-wzcas4zd	9	6	in	in	IN
cord-312119-wzcas4zd	9	7	silico	silico	NNS
cord-312119-wzcas4zd	9	8	identified	identify	VBD
cord-312119-wzcas4zd	9	9	immunodominant	immunodominant	JJ
cord-312119-wzcas4zd	9	10	epitopes	epitope	NNS
cord-312119-wzcas4zd	9	11	from	from	IN
cord-312119-wzcas4zd	9	12	F18ac	F18ac	NNP
cord-312119-wzcas4zd	9	13	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	9	14	subunit	subunit	NN
cord-312119-wzcas4zd	9	15	FedF	FedF	NNP
cord-312119-wzcas4zd	9	16	which	which	WDT
cord-312119-wzcas4zd	9	17	plays	play	VBZ
cord-312119-wzcas4zd	9	18	a	a	DT
cord-312119-wzcas4zd	9	19	critical	critical	JJ
cord-312119-wzcas4zd	9	20	role	role	NN
cord-312119-wzcas4zd	9	21	in	in	IN
cord-312119-wzcas4zd	9	22	F18	f18	JJ
cord-312119-wzcas4zd	9	23	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	9	24	adherence	adherence	NN
cord-312119-wzcas4zd	9	25	,	,	,
cord-312119-wzcas4zd	9	26	genetically	genetically	RB
cord-312119-wzcas4zd	9	27	fused	fuse	VBN
cord-312119-wzcas4zd	9	28	each	each	DT
cord-312119-wzcas4zd	9	29	epitope	epitope	NN
cord-312119-wzcas4zd	9	30	to	to	IN
cord-312119-wzcas4zd	9	31	a	a	DT
cord-312119-wzcas4zd	9	32	carrier	carrier	NN
cord-312119-wzcas4zd	9	33	,	,	,
cord-312119-wzcas4zd	9	34	examined	examine	VBD
cord-312119-wzcas4zd	9	35	immunogenicity	immunogenicity	NN
cord-312119-wzcas4zd	9	36	of	of	IN
cord-312119-wzcas4zd	9	37	each	each	DT
cord-312119-wzcas4zd	9	38	epitope	epitope	NN
cord-312119-wzcas4zd	9	39	fusion	fusion	NN
cord-312119-wzcas4zd	9	40	,	,	,
cord-312119-wzcas4zd	9	41	and	and	CC
cord-312119-wzcas4zd	9	42	determined	determine	VBD
cord-312119-wzcas4zd	9	43	epitope	epitope	NN
cord-312119-wzcas4zd	9	44	-	-	HYPH
cord-312119-wzcas4zd	9	45	derived	derive	VBN
cord-312119-wzcas4zd	9	46	antibodies	antibody	NNS
cord-312119-wzcas4zd	9	47	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	9	48	activities	activity	NNS
cord-312119-wzcas4zd	9	49	against	against	IN
cord-312119-wzcas4zd	9	50	F18	f18	JJ
cord-312119-wzcas4zd	9	51	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	9	52	adherence	adherence	NN
cord-312119-wzcas4zd	9	53	.	.	.
cord-312119-wzcas4zd	10	1	Data	datum	NNS
cord-312119-wzcas4zd	10	2	showed	show	VBD
cord-312119-wzcas4zd	10	3	that	that	IN
cord-312119-wzcas4zd	10	4	seven	seven	CD
cord-312119-wzcas4zd	10	5	immune	immune	JJ
cord-312119-wzcas4zd	10	6	-	-	HYPH
cord-312119-wzcas4zd	10	7	dominant	dominant	JJ
cord-312119-wzcas4zd	10	8	epitopes	epitope	NNS
cord-312119-wzcas4zd	10	9	were	be	VBD
cord-312119-wzcas4zd	10	10	identified	identify	VBN
cord-312119-wzcas4zd	10	11	from	from	IN
cord-312119-wzcas4zd	10	12	FedF	FedF	NNP
cord-312119-wzcas4zd	10	13	subunit	subunit	NN
cord-312119-wzcas4zd	10	14	.	.	.
cord-312119-wzcas4zd	11	1	Fused	fuse	VBN
cord-312119-wzcas4zd	11	2	to	to	IN
cord-312119-wzcas4zd	11	3	heterologous	heterologous	JJ
cord-312119-wzcas4zd	11	4	human	human	JJ
cord-312119-wzcas4zd	11	5	ETEC	etec	JJ
cord-312119-wzcas4zd	11	6	adhesin	adhesin	NN
cord-312119-wzcas4zd	11	7	subunit	subunit	NN
cord-312119-wzcas4zd	11	8	CfaB	CfaB	NNP
cord-312119-wzcas4zd	11	9	,	,	,
cord-312119-wzcas4zd	11	10	epitope	epitope	NN
cord-312119-wzcas4zd	11	11	fusions	fusion	NNS
cord-312119-wzcas4zd	11	12	induced	induce	VBD
cord-312119-wzcas4zd	11	13	anti	anti	JJ
cord-312119-wzcas4zd	11	14	-	-	JJ
cord-312119-wzcas4zd	11	15	F18	f18	JJ
cord-312119-wzcas4zd	11	16	antibodies	antibody	NNS
cord-312119-wzcas4zd	11	17	in	in	IN
cord-312119-wzcas4zd	11	18	subcutaneously	subcutaneously	RB
cord-312119-wzcas4zd	11	19	immunized	immunize	VBN
cord-312119-wzcas4zd	11	20	mice	mouse	NNS
cord-312119-wzcas4zd	11	21	.	.	.
cord-312119-wzcas4zd	12	1	Moreover	moreover	RB
cord-312119-wzcas4zd	12	2	,	,	,
cord-312119-wzcas4zd	12	3	antibodies	antibody	NNS
cord-312119-wzcas4zd	12	4	derived	derive	VBN
cord-312119-wzcas4zd	12	5	from	from	IN
cord-312119-wzcas4zd	12	6	each	each	DT
cord-312119-wzcas4zd	12	7	fusion	fusion	NN
cord-312119-wzcas4zd	12	8	significantly	significantly	RB
cord-312119-wzcas4zd	12	9	blocked	block	VBD
cord-312119-wzcas4zd	12	10	adherence	adherence	NN
cord-312119-wzcas4zd	12	11	of	of	IN
cord-312119-wzcas4zd	12	12	a	a	DT
cord-312119-wzcas4zd	12	13	F18-fimbrial	F18-fimbrial	NNP
cord-312119-wzcas4zd	12	14	E.	E.	NNP
cord-312119-wzcas4zd	12	15	coli	coli	NNS
cord-312119-wzcas4zd	12	16	bacteria	bacteria	NNS
cord-312119-wzcas4zd	12	17	to	to	IN
cord-312119-wzcas4zd	12	18	pig	pig	NN
cord-312119-wzcas4zd	12	19	intestinal	intestinal	JJ
cord-312119-wzcas4zd	12	20	cell	cell	NN
cord-312119-wzcas4zd	12	21	line	line	NN
cord-312119-wzcas4zd	12	22	IPEC	IPEC	NNP
cord-312119-wzcas4zd	12	23	-	-	HYPH
cord-312119-wzcas4zd	12	24	J2	J2	NNP
cord-312119-wzcas4zd	12	25	.	.	.
cord-312119-wzcas4zd	13	1	While	while	IN
cord-312119-wzcas4zd	13	2	all	all	DT
cord-312119-wzcas4zd	13	3	seven	seven	CD
cord-312119-wzcas4zd	13	4	epitopes	epitope	NNS
cord-312119-wzcas4zd	13	5	exhibited	exhibit	VBN
cord-312119-wzcas4zd	13	6	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	13	7	activity	activity	NN
cord-312119-wzcas4zd	13	8	,	,	,
cord-312119-wzcas4zd	13	9	results	result	NNS
cord-312119-wzcas4zd	13	10	from	from	IN
cord-312119-wzcas4zd	13	11	this	this	DT
cord-312119-wzcas4zd	13	12	study	study	NN
cord-312119-wzcas4zd	13	13	identified	identify	VBD
cord-312119-wzcas4zd	13	14	FedF	FedF	NNP
cord-312119-wzcas4zd	13	15	epitopes	epitope	NNS
cord-312119-wzcas4zd	13	16	#	#	$
cord-312119-wzcas4zd	13	17	3	3	CD
cord-312119-wzcas4zd	13	18	(	(	-LRB-
cord-312119-wzcas4zd	13	19	IPSSSGTLTCQAGT	IPSSSGTLTCQAGT	NNP
cord-312119-wzcas4zd	13	20	)	)	-RRB-
cord-312119-wzcas4zd	13	21	and	and	CC
cord-312119-wzcas4zd	13	22	#	#	$
cord-312119-wzcas4zd	13	23	7	7	CD
cord-312119-wzcas4zd	14	1	(	(	-LRB-
cord-312119-wzcas4zd	14	2	QPDATGSWYD	qpdatgswyd	NN
cord-312119-wzcas4zd	14	3	)	)	-RRB-
cord-312119-wzcas4zd	15	1	the	the	DT
cord-312119-wzcas4zd	15	2	most	most	RBS
cord-312119-wzcas4zd	15	3	effective	effective	JJ
cord-312119-wzcas4zd	15	4	for	for	IN
cord-312119-wzcas4zd	15	5	antibodies	antibody	NNS
cord-312119-wzcas4zd	15	6	against	against	IN
cord-312119-wzcas4zd	15	7	F18	f18	JJ
cord-312119-wzcas4zd	15	8	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	15	9	adherence	adherence	NN
cord-312119-wzcas4zd	15	10	,	,	,
cord-312119-wzcas4zd	15	11	and	and	CC
cord-312119-wzcas4zd	15	12	suggested	suggest	VBD
cord-312119-wzcas4zd	15	13	their	-PRON-	PRP$
cord-312119-wzcas4zd	15	14	future	future	JJ
cord-312119-wzcas4zd	15	15	application	application	NN
cord-312119-wzcas4zd	15	16	in	in	IN
cord-312119-wzcas4zd	15	17	PWD	pwd	NN
cord-312119-wzcas4zd	15	18	vaccine	vaccine	NN
cord-312119-wzcas4zd	15	19	development	development	NN
cord-312119-wzcas4zd	15	20	.	.	.
cord-312119-wzcas4zd	16	1	Post	post	JJ
cord-312119-wzcas4zd	16	2	-	-	JJ
cord-312119-wzcas4zd	16	3	weaning	wean	VBG
cord-312119-wzcas4zd	16	4	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	16	5	(	(	-LRB-
cord-312119-wzcas4zd	16	6	PWD	pwd	NN
cord-312119-wzcas4zd	16	7	)	)	-RRB-
cord-312119-wzcas4zd	16	8	is	be	VBZ
cord-312119-wzcas4zd	16	9	one	one	CD
cord-312119-wzcas4zd	16	10	of	of	IN
cord-312119-wzcas4zd	16	11	the	the	DT
cord-312119-wzcas4zd	16	12	most	most	RBS
cord-312119-wzcas4zd	16	13	important	important	JJ
cord-312119-wzcas4zd	16	14	swine	swine	NN
cord-312119-wzcas4zd	16	15	diseases	disease	NNS
cord-312119-wzcas4zd	16	16	(	(	-LRB-
cord-312119-wzcas4zd	16	17	Fairbrother	Fairbrother	NNP
cord-312119-wzcas4zd	16	18	et	et	NNP
cord-312119-wzcas4zd	16	19	al	al	NNP
cord-312119-wzcas4zd	16	20	.	.	NNP
cord-312119-wzcas4zd	16	21	,	,	,
cord-312119-wzcas4zd	16	22	2005	2005	CD
cord-312119-wzcas4zd	16	23	;	;	:
cord-312119-wzcas4zd	16	24	USDA	USDA	NNP
cord-312119-wzcas4zd	16	25	,	,	,
cord-312119-wzcas4zd	16	26	2002	2002	CD
cord-312119-wzcas4zd	16	27	)	)	-RRB-
cord-312119-wzcas4zd	16	28	.	.	.
cord-312119-wzcas4zd	17	1	Piglets	piglet	NNS
cord-312119-wzcas4zd	17	2	commonly	commonly	RB
cord-312119-wzcas4zd	17	3	develop	develop	VBP
cord-312119-wzcas4zd	17	4	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	17	5	3	3	CD
cord-312119-wzcas4zd	17	6	-	-	SYM
cord-312119-wzcas4zd	17	7	10	10	CD
cord-312119-wzcas4zd	17	8	days	day	NNS
cord-312119-wzcas4zd	17	9	after	after	IN
cord-312119-wzcas4zd	17	10	they	-PRON-	PRP
cord-312119-wzcas4zd	17	11	are	be	VBP
cord-312119-wzcas4zd	17	12	weaned	wean	VBN
cord-312119-wzcas4zd	17	13	,	,	,
cord-312119-wzcas4zd	17	14	a	a	DT
cord-312119-wzcas4zd	17	15	clinical	clinical	JJ
cord-312119-wzcas4zd	17	16	condition	condition	NN
cord-312119-wzcas4zd	17	17	called	call	VBN
cord-312119-wzcas4zd	17	18	PWD	pwd	NN
cord-312119-wzcas4zd	17	19	.	.	.
cord-312119-wzcas4zd	18	1	PWD	PWD	NNP
cord-312119-wzcas4zd	18	2	is	be	VBZ
cord-312119-wzcas4zd	18	3	mainly	mainly	RB
cord-312119-wzcas4zd	18	4	caused	cause	VBN
cord-312119-wzcas4zd	18	5	by	by	IN
cord-312119-wzcas4zd	18	6	pathogenic	pathogenic	JJ
cord-312119-wzcas4zd	18	7	bacteria	bacteria	NNS
cord-312119-wzcas4zd	18	8	and	and	CC
cord-312119-wzcas4zd	18	9	viruses	virus	NNS
cord-312119-wzcas4zd	18	10	including	include	VBG
cord-312119-wzcas4zd	18	11	diarrheagenic	diarrheagenic	NNP
cord-312119-wzcas4zd	18	12	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	18	13	coli	coli	NNS
cord-312119-wzcas4zd	18	14	,	,	,
cord-312119-wzcas4zd	18	15	coronaviruses	coronaviruse	NNS
cord-312119-wzcas4zd	18	16	[	[	-LRB-
cord-312119-wzcas4zd	18	17	transmissible	transmissible	JJ
cord-312119-wzcas4zd	18	18	gastroenteritis	gastroenteritis	NN
cord-312119-wzcas4zd	18	19	(	(	-LRB-
cord-312119-wzcas4zd	18	20	TGE	TGE	NNP
cord-312119-wzcas4zd	18	21	)	)	-RRB-
cord-312119-wzcas4zd	18	22	and	and	CC
cord-312119-wzcas4zd	18	23	porcine	porcine	JJ
cord-312119-wzcas4zd	18	24	epidemic	epidemic	NN
cord-312119-wzcas4zd	18	25	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	18	26	virus	virus	NN
cord-312119-wzcas4zd	18	27	(	(	-LRB-
cord-312119-wzcas4zd	18	28	PEDV	PEDV	NNP
cord-312119-wzcas4zd	18	29	)	)	-RRB-
cord-312119-wzcas4zd	18	30	]	]	-RRB-
cord-312119-wzcas4zd	18	31	and	and	CC
cord-312119-wzcas4zd	18	32	rotaviruses	rotavirus	NNS
cord-312119-wzcas4zd	18	33	;	;	:
cord-312119-wzcas4zd	18	34	however	however	RB
cord-312119-wzcas4zd	18	35	,	,	,
cord-312119-wzcas4zd	18	36	diarrheagenic	diarrheagenic	NNP
cord-312119-wzcas4zd	18	37	E.	E.	NNP
cord-312119-wzcas4zd	18	38	coli	coli	NNS
cord-312119-wzcas4zd	18	39	have	have	VBP
cord-312119-wzcas4zd	18	40	a	a	DT
cord-312119-wzcas4zd	18	41	central	central	JJ
cord-312119-wzcas4zd	18	42	role	role	NN
cord-312119-wzcas4zd	18	43	in	in	IN
cord-312119-wzcas4zd	18	44	the	the	DT
cord-312119-wzcas4zd	18	45	etiology	etiology	NN
cord-312119-wzcas4zd	18	46	of	of	IN
cord-312119-wzcas4zd	18	47	PWD	pwd	NN
cord-312119-wzcas4zd	18	48	(	(	-LRB-
cord-312119-wzcas4zd	18	49	Hampson	Hampson	NNP
cord-312119-wzcas4zd	18	50	,	,	,
cord-312119-wzcas4zd	18	51	1994	1994	CD
cord-312119-wzcas4zd	18	52	)	)	-RRB-
cord-312119-wzcas4zd	18	53	.	.	.
cord-312119-wzcas4zd	19	1	PWD	pwd	NN
cord-312119-wzcas4zd	19	2	causes	cause	VBZ
cord-312119-wzcas4zd	19	3	weight	weight	NN
cord-312119-wzcas4zd	19	4	loss	loss	NN
cord-312119-wzcas4zd	19	5	,	,	,
cord-312119-wzcas4zd	19	6	slow	slow	JJ
cord-312119-wzcas4zd	19	7	growth	growth	NN
cord-312119-wzcas4zd	19	8	and	and	CC
cord-312119-wzcas4zd	19	9	acute	acute	JJ
cord-312119-wzcas4zd	19	10	death	death	NN
cord-312119-wzcas4zd	19	11	in	in	IN
cord-312119-wzcas4zd	19	12	recently	recently	RB
cord-312119-wzcas4zd	19	13	weaned	wean	VBN
cord-312119-wzcas4zd	19	14	pigs	pig	NNS
cord-312119-wzcas4zd	19	15	,	,	,
cord-312119-wzcas4zd	19	16	resulting	result	VBG
cord-312119-wzcas4zd	19	17	in	in	IN
cord-312119-wzcas4zd	19	18	economic	economic	JJ
cord-312119-wzcas4zd	19	19	losses	loss	NNS
cord-312119-wzcas4zd	19	20	to	to	IN
cord-312119-wzcas4zd	19	21	swine	swine	NN
cord-312119-wzcas4zd	19	22	producers	producer	NNS
cord-312119-wzcas4zd	19	23	in	in	IN
cord-312119-wzcas4zd	19	24	the	the	DT
cord-312119-wzcas4zd	19	25	US	US	NNP
cord-312119-wzcas4zd	19	26	and	and	CC
cord-312119-wzcas4zd	19	27	other	other	JJ
cord-312119-wzcas4zd	19	28	countries	country	NNS
cord-312119-wzcas4zd	19	29	(	(	-LRB-
cord-312119-wzcas4zd	19	30	Haesebrouck	Haesebrouck	NNP
cord-312119-wzcas4zd	19	31	et	et	NNP
cord-312119-wzcas4zd	19	32	al	al	NNP
cord-312119-wzcas4zd	19	33	.	.	NNP
cord-312119-wzcas4zd	19	34	,	,	,
cord-312119-wzcas4zd	19	35	2004	2004	CD
cord-312119-wzcas4zd	19	36	;	;	:
cord-312119-wzcas4zd	19	37	Nagy	Nagy	NNP
cord-312119-wzcas4zd	19	38	and	and	CC
cord-312119-wzcas4zd	19	39	Fekete	Fekete	NNP
cord-312119-wzcas4zd	19	40	,	,	,
cord-312119-wzcas4zd	19	41	1999	1999	CD
cord-312119-wzcas4zd	19	42	;	;	:
cord-312119-wzcas4zd	19	43	Verdonck	Verdonck	NNP
cord-312119-wzcas4zd	19	44	et	et	NNP
cord-312119-wzcas4zd	19	45	al	al	NNP
cord-312119-wzcas4zd	19	46	.	.	NNP
cord-312119-wzcas4zd	19	47	,	,	,
cord-312119-wzcas4zd	19	48	2002	2002	CD
cord-312119-wzcas4zd	19	49	;	;	:
cord-312119-wzcas4zd	19	50	Vu	Vu	NNP
cord-312119-wzcas4zd	19	51	-	-	HYPH
cord-312119-wzcas4zd	19	52	Khac	Khac	NNP
cord-312119-wzcas4zd	19	53	et	et	NNP
cord-312119-wzcas4zd	19	54	al	al	NNP
cord-312119-wzcas4zd	19	55	.	.	NNP
cord-312119-wzcas4zd	19	56	,	,	,
cord-312119-wzcas4zd	19	57	2007	2007	CD
cord-312119-wzcas4zd	19	58	)	)	-RRB-
cord-312119-wzcas4zd	19	59	.	.	.
cord-312119-wzcas4zd	20	1	Diarrhea	diarrhea	NN
cord-312119-wzcas4zd	20	2	is	be	VBZ
cord-312119-wzcas4zd	20	3	also	also	RB
cord-312119-wzcas4zd	20	4	a	a	DT
cord-312119-wzcas4zd	20	5	main	main	JJ
cord-312119-wzcas4zd	20	6	reason	reason	NN
cord-312119-wzcas4zd	20	7	for	for	IN
cord-312119-wzcas4zd	20	8	using	use	VBG
cord-312119-wzcas4zd	20	9	antibiotics	antibiotic	NNS
cord-312119-wzcas4zd	20	10	on	on	IN
cord-312119-wzcas4zd	20	11	swine	swine	NN
cord-312119-wzcas4zd	20	12	farms	farm	NNS
cord-312119-wzcas4zd	20	13	.	.	.
cord-312119-wzcas4zd	21	1	Antibiotic	antibiotic	JJ
cord-312119-wzcas4zd	21	2	exposure	exposure	NN
cord-312119-wzcas4zd	21	3	is	be	VBZ
cord-312119-wzcas4zd	21	4	linked	link	VBN
cord-312119-wzcas4zd	21	5	to	to	IN
cord-312119-wzcas4zd	21	6	antimicrobial	antimicrobial	JJ
cord-312119-wzcas4zd	21	7	resistance	resistance	NN
cord-312119-wzcas4zd	21	8	(	(	-LRB-
cord-312119-wzcas4zd	21	9	AMR	AMR	NNP
cord-312119-wzcas4zd	21	10	)	)	-RRB-
cord-312119-wzcas4zd	21	11	,	,	,
cord-312119-wzcas4zd	21	12	casting	cast	VBG
cord-312119-wzcas4zd	21	13	a	a	DT
cord-312119-wzcas4zd	21	14	major	major	JJ
cord-312119-wzcas4zd	21	15	concern	concern	NN
cord-312119-wzcas4zd	21	16	for	for	IN
cord-312119-wzcas4zd	21	17	animal	animal	NN
cord-312119-wzcas4zd	21	18	and	and	CC
cord-312119-wzcas4zd	21	19	human	human	JJ
cord-312119-wzcas4zd	21	20	health	health	NN
cord-312119-wzcas4zd	21	21	(	(	-LRB-
cord-312119-wzcas4zd	21	22	Docic	Docic	NNP
cord-312119-wzcas4zd	21	23	and	and	CC
cord-312119-wzcas4zd	21	24	Bilkei	Bilkei	NNP
cord-312119-wzcas4zd	21	25	,	,	,
cord-312119-wzcas4zd	21	26	2003	2003	CD
cord-312119-wzcas4zd	21	27	;	;	:
cord-312119-wzcas4zd	21	28	Mishra	Mishra	NNP
cord-312119-wzcas4zd	21	29	et	et	NNP
cord-312119-wzcas4zd	21	30	al	al	NNP
cord-312119-wzcas4zd	21	31	.	.	NNP
cord-312119-wzcas4zd	21	32	,	,	,
cord-312119-wzcas4zd	21	33	2012	2012	CD
cord-312119-wzcas4zd	21	34	;	;	:
cord-312119-wzcas4zd	21	35	Torjesen	Torjesen	NNP
cord-312119-wzcas4zd	21	36	,	,	,
cord-312119-wzcas4zd	21	37	2016	2016	CD
cord-312119-wzcas4zd	21	38	)	)	-RRB-
cord-312119-wzcas4zd	21	39	.	.	.
cord-312119-wzcas4zd	22	1	However	however	RB
cord-312119-wzcas4zd	22	2	,	,	,
cord-312119-wzcas4zd	22	3	a	a	DT
cord-312119-wzcas4zd	22	4	ban	ban	NN
cord-312119-wzcas4zd	22	5	on	on	IN
cord-312119-wzcas4zd	22	6	the	the	DT
cord-312119-wzcas4zd	22	7	use	use	NN
cord-312119-wzcas4zd	22	8	of	of	IN
cord-312119-wzcas4zd	22	9	food	food	NN
cord-312119-wzcas4zd	22	10	animal	animal	NN
cord-312119-wzcas4zd	22	11	growth	growth	NN
cord-312119-wzcas4zd	22	12	promoting	promote	VBG
cord-312119-wzcas4zd	22	13	antibiotics	antibiotic	NNS
cord-312119-wzcas4zd	22	14	in	in	IN
cord-312119-wzcas4zd	22	15	Scandinavia	Scandinavia	NNP
cord-312119-wzcas4zd	22	16	and	and	CC
cord-312119-wzcas4zd	22	17	Europe	Europe	NNP
cord-312119-wzcas4zd	22	18	spiked	spike	VBD
cord-312119-wzcas4zd	22	19	PWD	pwd	NN
cord-312119-wzcas4zd	22	20	outbreaks	outbreak	NNS
cord-312119-wzcas4zd	22	21	(	(	-LRB-
cord-312119-wzcas4zd	22	22	Casewell	Casewell	NNP
cord-312119-wzcas4zd	22	23	et	et	FW
cord-312119-wzcas4zd	22	24	al	al	NNP
cord-312119-wzcas4zd	22	25	.	.	NNP
cord-312119-wzcas4zd	22	26	,	,	,
cord-312119-wzcas4zd	22	27	2003	2003	CD
cord-312119-wzcas4zd	22	28	)	)	-RRB-
cord-312119-wzcas4zd	22	29	,	,	,
cord-312119-wzcas4zd	22	30	urgently	urgently	RB
cord-312119-wzcas4zd	22	31	calling	call	VBG
cord-312119-wzcas4zd	22	32	for	for	IN
cord-312119-wzcas4zd	22	33	alternative	alternative	JJ
cord-312119-wzcas4zd	22	34	effective	effective	JJ
cord-312119-wzcas4zd	22	35	prevention	prevention	NN
cord-312119-wzcas4zd	22	36	strategies	strategy	NNS
cord-312119-wzcas4zd	22	37	against	against	IN
cord-312119-wzcas4zd	22	38	PWD	pwd	NN
cord-312119-wzcas4zd	22	39	.	.	.
cord-312119-wzcas4zd	23	1	Vaccination	vaccination	NN
cord-312119-wzcas4zd	23	2	would	would	MD
cord-312119-wzcas4zd	23	3	be	be	VB
cord-312119-wzcas4zd	23	4	the	the	DT
cord-312119-wzcas4zd	23	5	most	most	RBS
cord-312119-wzcas4zd	23	6	economical	economical	JJ
cord-312119-wzcas4zd	23	7	and	and	CC
cord-312119-wzcas4zd	23	8	likely	likely	JJ
cord-312119-wzcas4zd	23	9	effective	effective	JJ
cord-312119-wzcas4zd	23	10	approach	approach	NN
cord-312119-wzcas4zd	23	11	to	to	TO
cord-312119-wzcas4zd	23	12	control	control	VB
cord-312119-wzcas4zd	23	13	PWD	pwd	NN
cord-312119-wzcas4zd	23	14	and	and	CC
cord-312119-wzcas4zd	23	15	an	an	DT
cord-312119-wzcas4zd	23	16	effective	effective	JJ
cord-312119-wzcas4zd	23	17	means	mean	NNS
cord-312119-wzcas4zd	23	18	to	to	TO
cord-312119-wzcas4zd	23	19	reduce	reduce	VB
cord-312119-wzcas4zd	23	20	the	the	DT
cord-312119-wzcas4zd	23	21	use	use	NN
cord-312119-wzcas4zd	23	22	of	of	IN
cord-312119-wzcas4zd	23	23	antibiotics	antibiotic	NNS
cord-312119-wzcas4zd	23	24	.	.	.
cord-312119-wzcas4zd	24	1	Though	though	IN
cord-312119-wzcas4zd	24	2	there	there	EX
cord-312119-wzcas4zd	24	3	are	be	VBP
cord-312119-wzcas4zd	24	4	products	product	NNS
cord-312119-wzcas4zd	24	5	on	on	IN
cord-312119-wzcas4zd	24	6	the	the	DT
cord-312119-wzcas4zd	24	7	market	market	NN
cord-312119-wzcas4zd	24	8	,	,	,
cord-312119-wzcas4zd	24	9	truly	truly	RB
cord-312119-wzcas4zd	24	10	effective	effective	JJ
cord-312119-wzcas4zd	24	11	PWD	pwd	NN
cord-312119-wzcas4zd	24	12	vaccines	vaccine	NNS
cord-312119-wzcas4zd	24	13	are	be	VBP
cord-312119-wzcas4zd	24	14	urgently	urgently	RB
cord-312119-wzcas4zd	24	15	needed	need	VBN
cord-312119-wzcas4zd	24	16	(	(	-LRB-
cord-312119-wzcas4zd	24	17	Fairbrother	Fairbrother	NNP
cord-312119-wzcas4zd	24	18	et	et	NNP
cord-312119-wzcas4zd	24	19	al	al	NNP
cord-312119-wzcas4zd	24	20	.	.	NNP
cord-312119-wzcas4zd	24	21	,	,	,
cord-312119-wzcas4zd	24	22	2005	2005	CD
cord-312119-wzcas4zd	24	23	;	;	:
cord-312119-wzcas4zd	25	1	Melkebeek	Melkebeek	NNP
cord-312119-wzcas4zd	25	2	et	et	NNP
cord-312119-wzcas4zd	25	3	al	al	NNP
cord-312119-wzcas4zd	25	4	.	.	NNP
cord-312119-wzcas4zd	25	5	,	,	,
cord-312119-wzcas4zd	25	6	2013	2013	CD
cord-312119-wzcas4zd	25	7	;	;	:
cord-312119-wzcas4zd	25	8	Zhang	Zhang	NNP
cord-312119-wzcas4zd	25	9	,	,	,
cord-312119-wzcas4zd	25	10	2014	2014	CD
cord-312119-wzcas4zd	25	11	)	)	-RRB-
cord-312119-wzcas4zd	25	12	.	.	.
cord-312119-wzcas4zd	26	1	Of	of	IN
cord-312119-wzcas4zd	26	2	the	the	DT
cord-312119-wzcas4zd	26	3	diarrheagenic	diarrheagenic	JJ
cord-312119-wzcas4zd	26	4	E.	E.	NNP
cord-312119-wzcas4zd	26	5	coli	coli	NNS
cord-312119-wzcas4zd	26	6	,	,	,
cord-312119-wzcas4zd	26	7	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	26	8	E.	E.	NNP
cord-312119-wzcas4zd	26	9	coli	coli	NNS
cord-312119-wzcas4zd	26	10	(	(	-LRB-
cord-312119-wzcas4zd	26	11	ETEC	ETEC	NNP
cord-312119-wzcas4zd	26	12	)	)	-RRB-
cord-312119-wzcas4zd	26	13	is	be	VBZ
cord-312119-wzcas4zd	26	14	the	the	DT
cord-312119-wzcas4zd	26	15	most	most	RBS
cord-312119-wzcas4zd	26	16	common	common	JJ
cord-312119-wzcas4zd	26	17	cause	cause	NN
cord-312119-wzcas4zd	26	18	of	of	IN
cord-312119-wzcas4zd	26	19	PWD	pwd	NN
cord-312119-wzcas4zd	26	20	,	,	,
cord-312119-wzcas4zd	26	21	though	though	IN
cord-312119-wzcas4zd	26	22	the	the	DT
cord-312119-wzcas4zd	26	23	stress	stress	NN
cord-312119-wzcas4zd	26	24	of	of	IN
cord-312119-wzcas4zd	26	25	weaning	weaning	NN
cord-312119-wzcas4zd	26	26	,	,	,
cord-312119-wzcas4zd	26	27	absence	absence	NN
cord-312119-wzcas4zd	26	28	of	of	IN
cord-312119-wzcas4zd	26	29	maternally	maternally	RB
cord-312119-wzcas4zd	26	30	-	-	HYPH
cord-312119-wzcas4zd	26	31	derived	derive	VBN
cord-312119-wzcas4zd	26	32	enteric	enteric	JJ
cord-312119-wzcas4zd	26	33	antibodies	antibody	NNS
cord-312119-wzcas4zd	26	34	,	,	,
cord-312119-wzcas4zd	26	35	and	and	CC
cord-312119-wzcas4zd	26	36	dietary	dietary	JJ
cord-312119-wzcas4zd	26	37	change	change	NN
cord-312119-wzcas4zd	26	38	are	be	VBP
cord-312119-wzcas4zd	26	39	important	important	JJ
cord-312119-wzcas4zd	26	40	but	but	CC
cord-312119-wzcas4zd	26	41	indirect	indirect	JJ
cord-312119-wzcas4zd	26	42	factors	factor	NNS
cord-312119-wzcas4zd	26	43	of	of	IN
cord-312119-wzcas4zd	26	44	clinical	clinical	JJ
cord-312119-wzcas4zd	26	45	PWD	pwd	NN
cord-312119-wzcas4zd	26	46	(	(	-LRB-
cord-312119-wzcas4zd	26	47	Fairbrother	Fairbrother	NNP
cord-312119-wzcas4zd	26	48	et	et	NNP
cord-312119-wzcas4zd	26	49	al	al	NNP
cord-312119-wzcas4zd	26	50	.	.	NNP
cord-312119-wzcas4zd	26	51	,	,	,
cord-312119-wzcas4zd	26	52	2005	2005	CD
cord-312119-wzcas4zd	26	53	)	)	-RRB-
cord-312119-wzcas4zd	26	54	.	.	.
cord-312119-wzcas4zd	27	1	ETEC	ETEC	NNP
cord-312119-wzcas4zd	27	2	strains	strain	NNS
cord-312119-wzcas4zd	27	3	causing	cause	VBG
cord-312119-wzcas4zd	27	4	PWD	pwd	NN
cord-312119-wzcas4zd	27	5	produce	produce	VBP
cord-312119-wzcas4zd	27	6	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	27	7	and	and	CC
cord-312119-wzcas4zd	27	8	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	27	9	.	.	.
cord-312119-wzcas4zd	28	1	Fimbriae	fimbria	NNS
cord-312119-wzcas4zd	28	2	promote	promote	VBP
cord-312119-wzcas4zd	28	3	initial	initial	JJ
cord-312119-wzcas4zd	28	4	attachment	attachment	NN
cord-312119-wzcas4zd	28	5	to	to	TO
cord-312119-wzcas4zd	28	6	host	host	VB
cord-312119-wzcas4zd	28	7	cell	cell	NN
cord-312119-wzcas4zd	28	8	receptors	receptor	NNS
cord-312119-wzcas4zd	28	9	,	,	,
cord-312119-wzcas4zd	28	10	enabling	enable	VBG
cord-312119-wzcas4zd	28	11	colonization	colonization	NN
cord-312119-wzcas4zd	28	12	(	(	-LRB-
cord-312119-wzcas4zd	28	13	Smith	Smith	NNP
cord-312119-wzcas4zd	28	14	and	and	CC
cord-312119-wzcas4zd	28	15	Linggood	Linggood	NNP
cord-312119-wzcas4zd	28	16	,	,	,
cord-312119-wzcas4zd	28	17	1971	1971	CD
cord-312119-wzcas4zd	28	18	)	)	-RRB-
cord-312119-wzcas4zd	28	19	;	;	,
cord-312119-wzcas4zd	28	20	colonized	colonize	VBN
cord-312119-wzcas4zd	28	21	ETEC	ETEC	NNP
cord-312119-wzcas4zd	28	22	bacteria	bacteria	NNS
cord-312119-wzcas4zd	28	23	deliver	deliver	VBP
cord-312119-wzcas4zd	28	24	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	28	25	to	to	TO
cord-312119-wzcas4zd	28	26	host	host	VB
cord-312119-wzcas4zd	28	27	enterocytes	enterocyte	NNS
cord-312119-wzcas4zd	28	28	,	,	,
cord-312119-wzcas4zd	28	29	causing	cause	VBG
cord-312119-wzcas4zd	28	30	water	water	NN
cord-312119-wzcas4zd	28	31	and	and	CC
cord-312119-wzcas4zd	28	32	electrolyte	electrolyte	NN
cord-312119-wzcas4zd	28	33	hypersecretion	hypersecretion	NN
cord-312119-wzcas4zd	28	34	and	and	CC
cord-312119-wzcas4zd	28	35	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	28	36	(	(	-LRB-
cord-312119-wzcas4zd	28	37	Nataro	Nataro	NNP
cord-312119-wzcas4zd	28	38	and	and	CC
cord-312119-wzcas4zd	28	39	Kaper	Kaper	NNP
cord-312119-wzcas4zd	28	40	,	,	,
cord-312119-wzcas4zd	28	41	1998	1998	CD
cord-312119-wzcas4zd	28	42	)	)	-RRB-
cord-312119-wzcas4zd	28	43	.	.	.
cord-312119-wzcas4zd	29	1	Thus	thus	RB
cord-312119-wzcas4zd	29	2	,	,	,
cord-312119-wzcas4zd	29	3	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	29	4	and	and	CC
cord-312119-wzcas4zd	29	5	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	29	6	are	be	VBP
cord-312119-wzcas4zd	29	7	the	the	DT
cord-312119-wzcas4zd	29	8	major	major	JJ
cord-312119-wzcas4zd	29	9	virulence	virulence	NN
cord-312119-wzcas4zd	29	10	determinants	determinant	NNS
cord-312119-wzcas4zd	29	11	of	of	IN
cord-312119-wzcas4zd	29	12	ETEC	ETEC	NNP
cord-312119-wzcas4zd	29	13	,	,	,
cord-312119-wzcas4zd	29	14	and	and	CC
cord-312119-wzcas4zd	29	15	have	have	VBP
cord-312119-wzcas4zd	29	16	been	be	VBN
cord-312119-wzcas4zd	29	17	targeted	target	VBN
cord-312119-wzcas4zd	29	18	in	in	IN
cord-312119-wzcas4zd	29	19	intervention	intervention	NN
cord-312119-wzcas4zd	29	20	strategies	strategy	NNS
cord-312119-wzcas4zd	29	21	.	.	.
cord-312119-wzcas4zd	30	1	T	T	NNP
cord-312119-wzcas4zd	30	2	ETEC	ETEC	NNP
cord-312119-wzcas4zd	30	3	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	30	4	and	and	CC
cord-312119-wzcas4zd	30	5	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	30	6	are	be	VBP
cord-312119-wzcas4zd	30	7	immunologically	immunologically	RB
cord-312119-wzcas4zd	30	8	heterogeneous	heterogeneous	JJ
cord-312119-wzcas4zd	31	1	(	(	-LRB-
cord-312119-wzcas4zd	31	2	Gaastra	Gaastra	NNP
cord-312119-wzcas4zd	31	3	and	and	CC
cord-312119-wzcas4zd	31	4	de	de	NNP
cord-312119-wzcas4zd	31	5	Graaf	Graaf	NNP
cord-312119-wzcas4zd	31	6	,	,	,
cord-312119-wzcas4zd	31	7	1982	1982	CD
cord-312119-wzcas4zd	31	8	)	)	-RRB-
cord-312119-wzcas4zd	31	9	.	.	.
cord-312119-wzcas4zd	32	1	Fimbriae	Fimbriae	NNP
cord-312119-wzcas4zd	32	2	of	of	IN
cord-312119-wzcas4zd	32	3	ETEC	ETEC	NNP
cord-312119-wzcas4zd	32	4	causing	cause	VBG
cord-312119-wzcas4zd	32	5	PWD	pwd	NN
cord-312119-wzcas4zd	32	6	include	include	VBP
cord-312119-wzcas4zd	32	7	K88	K88	NNP
cord-312119-wzcas4zd	32	8	(	(	-LRB-
cord-312119-wzcas4zd	32	9	F4	F4	NNP
cord-312119-wzcas4zd	32	10	)	)	-RRB-
cord-312119-wzcas4zd	32	11	and	and	CC
cord-312119-wzcas4zd	32	12	F18	F18	NNP
cord-312119-wzcas4zd	32	13	,	,	,
cord-312119-wzcas4zd	32	14	and	and	CC
cord-312119-wzcas4zd	32	15	occasionally	occasionally	RB
cord-312119-wzcas4zd	32	16	K99	K99	NNP
cord-312119-wzcas4zd	32	17	(	(	-LRB-
cord-312119-wzcas4zd	32	18	F5	F5	NNP
cord-312119-wzcas4zd	32	19	)	)	-RRB-
cord-312119-wzcas4zd	32	20	,	,	,
cord-312119-wzcas4zd	32	21	987	987	CD
cord-312119-wzcas4zd	32	22	P	p	NN
cord-312119-wzcas4zd	32	23	(	(	-LRB-
cord-312119-wzcas4zd	32	24	F6	F6	NNP
cord-312119-wzcas4zd	32	25	)	)	-RRB-
cord-312119-wzcas4zd	32	26	and	and	CC
cord-312119-wzcas4zd	32	27	F41	F41	NNP
cord-312119-wzcas4zd	32	28	(	(	-LRB-
cord-312119-wzcas4zd	32	29	F7	f7	NN
cord-312119-wzcas4zd	32	30	)	)	-RRB-
cord-312119-wzcas4zd	32	31	(	(	-LRB-
cord-312119-wzcas4zd	32	32	Awad	Awad	NNP
cord-312119-wzcas4zd	32	33	-	-	HYPH
cord-312119-wzcas4zd	32	34	Masalmeh	Masalmeh	NNP
cord-312119-wzcas4zd	32	35	et	et	NNP
cord-312119-wzcas4zd	32	36	al	al	NNP
cord-312119-wzcas4zd	32	37	.	.	NNP
cord-312119-wzcas4zd	32	38	,	,	,
cord-312119-wzcas4zd	32	39	1982	1982	CD
cord-312119-wzcas4zd	32	40	;	;	:
cord-312119-wzcas4zd	32	41	Casey	Casey	NNP
cord-312119-wzcas4zd	32	42	and	and	CC
cord-312119-wzcas4zd	32	43	Moon	Moon	NNP
cord-312119-wzcas4zd	32	44	,	,	,
cord-312119-wzcas4zd	32	45	1990	1990	CD
cord-312119-wzcas4zd	32	46	;	;	:
cord-312119-wzcas4zd	32	47	Frydendahl	Frydendahl	NNP
cord-312119-wzcas4zd	32	48	,	,	,
cord-312119-wzcas4zd	32	49	2002	2002	CD
cord-312119-wzcas4zd	32	50	;	;	:
cord-312119-wzcas4zd	32	51	Moseley	Moseley	NNP
cord-312119-wzcas4zd	32	52	et	et	NNP
cord-312119-wzcas4zd	32	53	al	al	NNP
cord-312119-wzcas4zd	32	54	.	.	NNP
cord-312119-wzcas4zd	32	55	,	,	,
cord-312119-wzcas4zd	32	56	1986	1986	CD
cord-312119-wzcas4zd	32	57	;	;	:
cord-312119-wzcas4zd	32	58	Nagy	Nagy	NNP
cord-312119-wzcas4zd	32	59	et	et	NNP
cord-312119-wzcas4zd	32	60	al	al	NNP
cord-312119-wzcas4zd	32	61	.	.	NNP
cord-312119-wzcas4zd	32	62	,	,	,
cord-312119-wzcas4zd	32	63	1977	1977	CD
cord-312119-wzcas4zd	32	64	;	;	:
cord-312119-wzcas4zd	32	65	Zhang	Zhang	NNP
cord-312119-wzcas4zd	32	66	et	et	NNP
cord-312119-wzcas4zd	32	67	al	al	NNP
cord-312119-wzcas4zd	32	68	.	.	NNP
cord-312119-wzcas4zd	32	69	,	,	,
cord-312119-wzcas4zd	32	70	2007	2007	CD
cord-312119-wzcas4zd	32	71	)	)	-RRB-
cord-312119-wzcas4zd	32	72	.	.	.
cord-312119-wzcas4zd	33	1	Enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	33	2	produced	produce	VBN
cord-312119-wzcas4zd	33	3	by	by	IN
cord-312119-wzcas4zd	33	4	ETEC	ETEC	NNP
cord-312119-wzcas4zd	33	5	are	be	VBP
cord-312119-wzcas4zd	33	6	heat	heat	NN
cord-312119-wzcas4zd	33	7	-	-	HYPH
cord-312119-wzcas4zd	33	8	labile	labile	JJ
cord-312119-wzcas4zd	33	9	toxin	toxin	NN
cord-312119-wzcas4zd	33	10	(	(	-LRB-
cord-312119-wzcas4zd	33	11	LT	LT	NNP
cord-312119-wzcas4zd	33	12	)	)	-RRB-
cord-312119-wzcas4zd	33	13	,	,	,
cord-312119-wzcas4zd	33	14	heat	heat	NN
cord-312119-wzcas4zd	33	15	-	-	HYPH
cord-312119-wzcas4zd	33	16	stable	stable	JJ
cord-312119-wzcas4zd	33	17	toxin	toxin	NN
cord-312119-wzcas4zd	33	18	type	type	NN
cord-312119-wzcas4zd	33	19	I	-PRON-	PRP
cord-312119-wzcas4zd	33	20	(	(	-LRB-
cord-312119-wzcas4zd	33	21	STa	STa	NNP
cord-312119-wzcas4zd	33	22	)	)	-RRB-
cord-312119-wzcas4zd	33	23	,	,	,
cord-312119-wzcas4zd	33	24	heat	heat	NN
cord-312119-wzcas4zd	33	25	-	-	HYPH
cord-312119-wzcas4zd	33	26	stable	stable	JJ
cord-312119-wzcas4zd	33	27	toxin	toxin	NN
cord-312119-wzcas4zd	33	28	type	type	NN
cord-312119-wzcas4zd	33	29	II	II	NNP
cord-312119-wzcas4zd	33	30	(	(	-LRB-
cord-312119-wzcas4zd	33	31	STb	STb	NNP
cord-312119-wzcas4zd	33	32	)	)	-RRB-
cord-312119-wzcas4zd	33	33	,	,	,
cord-312119-wzcas4zd	33	34	Shiga	Shiga	NNP
cord-312119-wzcas4zd	33	35	toxin	toxin	NN
cord-312119-wzcas4zd	33	36	2e	2e	CD
cord-312119-wzcas4zd	33	37	(	(	-LRB-
cord-312119-wzcas4zd	33	38	Stx2e	Stx2e	NNP
cord-312119-wzcas4zd	33	39	)	)	-RRB-
cord-312119-wzcas4zd	33	40	and	and	CC
cord-312119-wzcas4zd	33	41	enteroaggregative	enteroaggregative	JJ
cord-312119-wzcas4zd	33	42	heat	heat	NN
cord-312119-wzcas4zd	33	43	-	-	HYPH
cord-312119-wzcas4zd	33	44	stable	stable	JJ
cord-312119-wzcas4zd	33	45	toxin	toxin	NN
cord-312119-wzcas4zd	33	46	type	type	NN
cord-312119-wzcas4zd	33	47	1	1	CD
cord-312119-wzcas4zd	33	48	(	(	-LRB-
cord-312119-wzcas4zd	33	49	EAST1	east1	NN
cord-312119-wzcas4zd	33	50	)	)	-RRB-
cord-312119-wzcas4zd	33	51	(	(	-LRB-
cord-312119-wzcas4zd	33	52	Frydendahl	Frydendahl	NNP
cord-312119-wzcas4zd	33	53	,	,	,
cord-312119-wzcas4zd	33	54	2002	2002	CD
cord-312119-wzcas4zd	33	55	;	;	:
cord-312119-wzcas4zd	33	56	Lee	Lee	NNP
cord-312119-wzcas4zd	33	57	et	et	NNP
cord-312119-wzcas4zd	33	58	al	al	NNP
cord-312119-wzcas4zd	33	59	.	.	NNP
cord-312119-wzcas4zd	33	60	,	,	,
cord-312119-wzcas4zd	33	61	1983	1983	CD
cord-312119-wzcas4zd	33	62	;	;	.
cord-312119-wzcas4zd	34	1	Moon	Moon	NNP
cord-312119-wzcas4zd	34	2	et	et	NNP
cord-312119-wzcas4zd	34	3	al	al	NNP
cord-312119-wzcas4zd	34	4	.	.	.
cord-312119-wzcas4zd	35	1	,	,	,
cord-312119-wzcas4zd	35	2	1980	1980	CD
cord-312119-wzcas4zd	35	3	;	;	:
cord-312119-wzcas4zd	35	4	Nakazawa	Nakazawa	NNP
cord-312119-wzcas4zd	35	5	et	et	FW
cord-312119-wzcas4zd	35	6	al	al	NNP
cord-312119-wzcas4zd	35	7	.	.	NNP
cord-312119-wzcas4zd	35	8	,	,	,
cord-312119-wzcas4zd	35	9	1987	1987	CD
cord-312119-wzcas4zd	35	10	;	;	.
cord-312119-wzcas4zd	36	1	Osek	Osek	NNP
cord-312119-wzcas4zd	36	2	,	,	,
cord-312119-wzcas4zd	36	3	1999b	1999b	CD
cord-312119-wzcas4zd	36	4	;	;	:
cord-312119-wzcas4zd	36	5	Zhang	Zhang	NNP
cord-312119-wzcas4zd	36	6	et	et	NNP
cord-312119-wzcas4zd	36	7	al	al	NNP
cord-312119-wzcas4zd	36	8	.	.	NNP
cord-312119-wzcas4zd	36	9	,	,	,
cord-312119-wzcas4zd	36	10	2007	2007	CD
cord-312119-wzcas4zd	36	11	)	)	-RRB-
cord-312119-wzcas4zd	36	12	.	.	.
cord-312119-wzcas4zd	37	1	Clinical	clinical	JJ
cord-312119-wzcas4zd	37	2	observations	observation	NNS
cord-312119-wzcas4zd	37	3	and	and	CC
cord-312119-wzcas4zd	37	4	epidemiological	epidemiological	JJ
cord-312119-wzcas4zd	37	5	studies	study	NNS
cord-312119-wzcas4zd	37	6	indicate	indicate	VBP
cord-312119-wzcas4zd	37	7	that	that	IN
cord-312119-wzcas4zd	37	8	a	a	DT
cord-312119-wzcas4zd	37	9	typical	typical	JJ
cord-312119-wzcas4zd	37	10	ETEC	etec	JJ
cord-312119-wzcas4zd	37	11	strain	strain	NN
cord-312119-wzcas4zd	37	12	expresses	express	VBZ
cord-312119-wzcas4zd	37	13	one	one	CD
cord-312119-wzcas4zd	37	14	and	and	CC
cord-312119-wzcas4zd	37	15	occasionally	occasionally	RB
cord-312119-wzcas4zd	37	16	two	two	CD
cord-312119-wzcas4zd	37	17	types	type	NNS
cord-312119-wzcas4zd	37	18	of	of	IN
cord-312119-wzcas4zd	37	19	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	37	20	and	and	CC
cord-312119-wzcas4zd	37	21	one	one	CD
cord-312119-wzcas4zd	37	22	,	,	,
cord-312119-wzcas4zd	37	23	two	two	CD
cord-312119-wzcas4zd	37	24	or	or	CC
cord-312119-wzcas4zd	37	25	more	more	JJR
cord-312119-wzcas4zd	37	26	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	37	27	(	(	-LRB-
cord-312119-wzcas4zd	37	28	Francis	Francis	NNP
cord-312119-wzcas4zd	37	29	,	,	,
cord-312119-wzcas4zd	37	30	2002	2002	CD
cord-312119-wzcas4zd	37	31	;	;	:
cord-312119-wzcas4zd	37	32	Frydendahl	Frydendahl	NNPS
cord-312119-wzcas4zd	37	33	,	,	,
cord-312119-wzcas4zd	37	34	2002	2002	CD
cord-312119-wzcas4zd	37	35	;	;	:
cord-312119-wzcas4zd	38	1	Zhang	Zhang	NNP
cord-312119-wzcas4zd	38	2	et	et	NNP
cord-312119-wzcas4zd	38	3	al	al	NNP
cord-312119-wzcas4zd	38	4	.	.	NNP
cord-312119-wzcas4zd	38	5	,	,	,
cord-312119-wzcas4zd	38	6	2007	2007	CD
cord-312119-wzcas4zd	38	7	)	)	-RRB-
cord-312119-wzcas4zd	38	8	.	.	.
cord-312119-wzcas4zd	39	1	Laboratory	laboratory	JJ
cord-312119-wzcas4zd	39	2	experimental	experimental	JJ
cord-312119-wzcas4zd	39	3	studies	study	NNS
cord-312119-wzcas4zd	39	4	demonstrated	demonstrate	VBD
cord-312119-wzcas4zd	39	5	that	that	IN
cord-312119-wzcas4zd	39	6	an	an	DT
cord-312119-wzcas4zd	39	7	ETEC	ETEC	NNP
cord-312119-wzcas4zd	39	8	strain	strain	NN
cord-312119-wzcas4zd	39	9	expressing	express	VBG
cord-312119-wzcas4zd	39	10	one	one	CD
cord-312119-wzcas4zd	39	11	type	type	NN
cord-312119-wzcas4zd	39	12	of	of	IN
cord-312119-wzcas4zd	39	13	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	39	14	and	and	CC
cord-312119-wzcas4zd	39	15	LT	LT	NNP
cord-312119-wzcas4zd	39	16	,	,	,
cord-312119-wzcas4zd	39	17	STb	STb	NNS
cord-312119-wzcas4zd	39	18	,	,	,
cord-312119-wzcas4zd	39	19	or	or	CC
cord-312119-wzcas4zd	39	20	STa	sta	NN
cord-312119-wzcas4zd	39	21	enterotoxin	enterotoxin	NN
cord-312119-wzcas4zd	39	22	causes	cause	VBZ
cord-312119-wzcas4zd	39	23	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	39	24	in	in	IN
cord-312119-wzcas4zd	39	25	young	young	JJ
cord-312119-wzcas4zd	39	26	pigs	pig	NNS
cord-312119-wzcas4zd	40	1	(	(	-LRB-
cord-312119-wzcas4zd	40	2	Berberov	Berberov	NNP
cord-312119-wzcas4zd	40	3	et	et	NNP
cord-312119-wzcas4zd	40	4	al	al	NNP
cord-312119-wzcas4zd	40	5	.	.	NNP
cord-312119-wzcas4zd	40	6	,	,	,
cord-312119-wzcas4zd	40	7	2004	2004	CD
cord-312119-wzcas4zd	41	1	;	;	:
cord-312119-wzcas4zd	41	2	Erume	Erume	NNP
cord-312119-wzcas4zd	41	3	et	et	NNP
cord-312119-wzcas4zd	41	4	al	al	NNP
cord-312119-wzcas4zd	41	5	.	.	.
cord-312119-wzcas4zd	42	1	,	,	,
cord-312119-wzcas4zd	42	2	2008	2008	CD
cord-312119-wzcas4zd	42	3	;	;	:
cord-312119-wzcas4zd	42	4	Zhang	Zhang	NNP
cord-312119-wzcas4zd	42	5	et	et	NNP
cord-312119-wzcas4zd	42	6	al	al	NNP
cord-312119-wzcas4zd	42	7	.	.	.
cord-312119-wzcas4zd	43	1	,	,	,
cord-312119-wzcas4zd	43	2	2006	2006	CD
cord-312119-wzcas4zd	43	3	Zhang	Zhang	NNP
cord-312119-wzcas4zd	43	4	et	et	NNP
cord-312119-wzcas4zd	43	5	al	al	NNP
cord-312119-wzcas4zd	43	6	.	.	NNP
cord-312119-wzcas4zd	43	7	,	,	,
cord-312119-wzcas4zd	43	8	,	,	,
cord-312119-wzcas4zd	43	9	2008	2008	CD
cord-312119-wzcas4zd	43	10	.	.	.
cord-312119-wzcas4zd	44	1	The	the	DT
cord-312119-wzcas4zd	44	2	optimal	optimal	JJ
cord-312119-wzcas4zd	44	3	prevention	prevention	NN
cord-312119-wzcas4zd	44	4	approach	approach	NN
cord-312119-wzcas4zd	44	5	would	would	MD
cord-312119-wzcas4zd	44	6	be	be	VB
cord-312119-wzcas4zd	44	7	to	to	TO
cord-312119-wzcas4zd	44	8	block	block	VB
cord-312119-wzcas4zd	44	9	attachment	attachment	NN
cord-312119-wzcas4zd	44	10	of	of	IN
cord-312119-wzcas4zd	44	11	different	different	JJ
cord-312119-wzcas4zd	44	12	ETEC	ETEC	NNP
cord-312119-wzcas4zd	44	13	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	44	14	to	to	TO
cord-312119-wzcas4zd	44	15	host	host	VB
cord-312119-wzcas4zd	44	16	receptors	receptor	NNS
cord-312119-wzcas4zd	44	17	and	and	CC
cord-312119-wzcas4zd	44	18	to	to	TO
cord-312119-wzcas4zd	44	19	eliminate	eliminate	VB
cord-312119-wzcas4zd	44	20	enterotoxicity	enterotoxicity	NN
cord-312119-wzcas4zd	44	21	of	of	IN
cord-312119-wzcas4zd	44	22	major	major	JJ
cord-312119-wzcas4zd	44	23	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	44	24	(	(	-LRB-
cord-312119-wzcas4zd	44	25	LT	LT	NNP
cord-312119-wzcas4zd	44	26	,	,	,
cord-312119-wzcas4zd	44	27	STs	STs	NNP
cord-312119-wzcas4zd	44	28	)	)	-RRB-
cord-312119-wzcas4zd	44	29	to	to	TO
cord-312119-wzcas4zd	44	30	host	host	VB
cord-312119-wzcas4zd	44	31	cells	cell	NNS
cord-312119-wzcas4zd	44	32	(	(	-LRB-
cord-312119-wzcas4zd	44	33	Walker	Walker	NNP
cord-312119-wzcas4zd	44	34	,	,	,
cord-312119-wzcas4zd	44	35	2005	2005	CD
cord-312119-wzcas4zd	44	36	;	;	:
cord-312119-wzcas4zd	44	37	Zhang	Zhang	NNP
cord-312119-wzcas4zd	44	38	,	,	,
cord-312119-wzcas4zd	44	39	2014	2014	CD
cord-312119-wzcas4zd	44	40	;	;	:
cord-312119-wzcas4zd	44	41	Zhang	Zhang	NNP
cord-312119-wzcas4zd	44	42	and	and	CC
cord-312119-wzcas4zd	44	43	Sack	Sack	NNP
cord-312119-wzcas4zd	44	44	,	,	,
cord-312119-wzcas4zd	44	45	2012	2012	CD
cord-312119-wzcas4zd	44	46	)	)	-RRB-
cord-312119-wzcas4zd	44	47	.	.	.
cord-312119-wzcas4zd	45	1	Blocking	block	VBG
cord-312119-wzcas4zd	45	2	attachment	attachment	NN
cord-312119-wzcas4zd	45	3	of	of	IN
cord-312119-wzcas4zd	45	4	all	all	DT
cord-312119-wzcas4zd	45	5	ETEC	etec	JJ
cord-312119-wzcas4zd	45	6	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	45	7	and	and	CC
cord-312119-wzcas4zd	45	8	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	45	9	against	against	IN
cord-312119-wzcas4zd	45	10	enterotoxicity	enterotoxicity	NN
cord-312119-wzcas4zd	45	11	of	of	IN
cord-312119-wzcas4zd	45	12	LT	LT	NNP
cord-312119-wzcas4zd	45	13	and	and	CC
cord-312119-wzcas4zd	45	14	STs	STs	NNPS
cord-312119-wzcas4zd	45	15	have	have	VBP
cord-312119-wzcas4zd	45	16	proven	prove	VBN
cord-312119-wzcas4zd	45	17	very	very	RB
cord-312119-wzcas4zd	45	18	challenging	challenging	JJ
cord-312119-wzcas4zd	45	19	.	.	.
cord-312119-wzcas4zd	46	1	However	however	RB
cord-312119-wzcas4zd	46	2	,	,	,
cord-312119-wzcas4zd	46	3	a	a	DT
cord-312119-wzcas4zd	46	4	recent	recent	JJ
cord-312119-wzcas4zd	46	5	breakthrough	breakthrough	NN
cord-312119-wzcas4zd	46	6	in	in	IN
cord-312119-wzcas4zd	46	7	antigen	antigen	NN
cord-312119-wzcas4zd	46	8	preparation	preparation	NN
cord-312119-wzcas4zd	46	9	by	by	IN
cord-312119-wzcas4zd	46	10	using	use	VBG
cord-312119-wzcas4zd	46	11	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	46	12	epitopes	epitope	NNS
cord-312119-wzcas4zd	46	13	and	and	CC
cord-312119-wzcas4zd	46	14	multiepitope	multiepitope	NN
cord-312119-wzcas4zd	46	15	-	-	HYPH
cord-312119-wzcas4zd	46	16	fusion	fusion	NN
cord-312119-wzcas4zd	46	17	-	-	HYPH
cord-312119-wzcas4zd	46	18	antigen	antigen	NN
cord-312119-wzcas4zd	46	19	(	(	-LRB-
cord-312119-wzcas4zd	46	20	MEFA	MEFA	NNP
cord-312119-wzcas4zd	46	21	)	)	-RRB-
cord-312119-wzcas4zd	46	22	technology	technology	NN
cord-312119-wzcas4zd	46	23	makes	make	VBZ
cord-312119-wzcas4zd	46	24	completion	completion	NN
cord-312119-wzcas4zd	46	25	of	of	IN
cord-312119-wzcas4zd	46	26	such	such	PDT
cord-312119-wzcas4zd	46	27	a	a	DT
cord-312119-wzcas4zd	46	28	task	task	NN
cord-312119-wzcas4zd	46	29	feasible	feasible	JJ
cord-312119-wzcas4zd	46	30	Nandre	Nandre	NNP
cord-312119-wzcas4zd	46	31	et	et	FW
cord-312119-wzcas4zd	46	32	al	al	NNP
cord-312119-wzcas4zd	46	33	.	.	.
cord-312119-wzcas4zd	47	1	,	,	,
cord-312119-wzcas4zd	47	2	2016	2016	CD
cord-312119-wzcas4zd	48	1	Ruan	Ruan	NNP
cord-312119-wzcas4zd	48	2	et	et	NNP
cord-312119-wzcas4zd	48	3	al	al	NNP
cord-312119-wzcas4zd	48	4	.	.	NNP
cord-312119-wzcas4zd	48	5	,	,	,
cord-312119-wzcas4zd	48	6	2014a	2014a	CD
cord-312119-wzcas4zd	48	7	.	.	.
cord-312119-wzcas4zd	49	1	Additionally	additionally	RB
cord-312119-wzcas4zd	49	2	,	,	,
cord-312119-wzcas4zd	49	3	molecular	molecular	JJ
cord-312119-wzcas4zd	49	4	epidemiological	epidemiological	JJ
cord-312119-wzcas4zd	49	5	studies	study	NNS
cord-312119-wzcas4zd	49	6	showed	show	VBD
cord-312119-wzcas4zd	49	7	that	that	IN
cord-312119-wzcas4zd	49	8	the	the	DT
cord-312119-wzcas4zd	49	9	vast	vast	JJ
cord-312119-wzcas4zd	49	10	majority	majority	NN
cord-312119-wzcas4zd	49	11	of	of	IN
cord-312119-wzcas4zd	49	12	ETEC	etec	JJ
cord-312119-wzcas4zd	49	13	strains	strain	NNS
cord-312119-wzcas4zd	49	14	causing	cause	VBG
cord-312119-wzcas4zd	49	15	PWD	pwd	NN
cord-312119-wzcas4zd	49	16	express	express	VBP
cord-312119-wzcas4zd	49	17	K88	K88	NNP
cord-312119-wzcas4zd	49	18	or	or	CC
cord-312119-wzcas4zd	49	19	F18	F18	NNP
cord-312119-wzcas4zd	49	20	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	49	21	in	in	IN
cord-312119-wzcas4zd	49	22	conjunction	conjunction	NN
cord-312119-wzcas4zd	49	23	with	with	IN
cord-312119-wzcas4zd	49	24	2	2	CD
cord-312119-wzcas4zd	49	25	-	-	SYM
cord-312119-wzcas4zd	49	26	3	3	CD
cord-312119-wzcas4zd	49	27	toxins	toxin	NNS
cord-312119-wzcas4zd	49	28	(	(	-LRB-
cord-312119-wzcas4zd	49	29	Frydendahl	Frydendahl	NNP
cord-312119-wzcas4zd	49	30	,	,	,
cord-312119-wzcas4zd	49	31	2002	2002	CD
cord-312119-wzcas4zd	49	32	;	;	:
cord-312119-wzcas4zd	49	33	Zhang	Zhang	NNP
cord-312119-wzcas4zd	49	34	et	et	NNP
cord-312119-wzcas4zd	49	35	al	al	NNP
cord-312119-wzcas4zd	49	36	.	.	NNP
cord-312119-wzcas4zd	49	37	,	,	,
cord-312119-wzcas4zd	49	38	2007	2007	CD
cord-312119-wzcas4zd	49	39	)	)	-RRB-
cord-312119-wzcas4zd	49	40	.	.	.
cord-312119-wzcas4zd	50	1	In	in	IN
cord-312119-wzcas4zd	50	2	the	the	DT
cord-312119-wzcas4zd	50	3	US	US	NNP
cord-312119-wzcas4zd	50	4	,	,	,
cord-312119-wzcas4zd	50	5	over	over	IN
cord-312119-wzcas4zd	50	6	95	95	CD
cord-312119-wzcas4zd	50	7	%	%	NN
cord-312119-wzcas4zd	50	8	of	of	IN
cord-312119-wzcas4zd	50	9	PWD	pwd	NN
cord-312119-wzcas4zd	50	10	cases	case	NNS
cord-312119-wzcas4zd	50	11	are	be	VBP
cord-312119-wzcas4zd	50	12	caused	cause	VBN
cord-312119-wzcas4zd	50	13	by	by	IN
cord-312119-wzcas4zd	50	14	K88	K88	NNP
cord-312119-wzcas4zd	50	15	or	or	CC
cord-312119-wzcas4zd	50	16	F18	F18	NNP
cord-312119-wzcas4zd	50	17	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	50	18	ETEC	ETEC	NNP
cord-312119-wzcas4zd	50	19	strains	strain	NNS
cord-312119-wzcas4zd	50	20	(	(	-LRB-
cord-312119-wzcas4zd	50	21	Francis	Francis	NNP
cord-312119-wzcas4zd	50	22	,	,	,
cord-312119-wzcas4zd	50	23	2002	2002	CD
cord-312119-wzcas4zd	50	24	;	;	:
cord-312119-wzcas4zd	51	1	Zhang	Zhang	NNP
cord-312119-wzcas4zd	51	2	et	et	NNP
cord-312119-wzcas4zd	51	3	al	al	NNP
cord-312119-wzcas4zd	51	4	.	.	NNP
cord-312119-wzcas4zd	51	5	,	,	,
cord-312119-wzcas4zd	51	6	2007	2007	CD
cord-312119-wzcas4zd	51	7	)	)	-RRB-
cord-312119-wzcas4zd	51	8	.	.	.
cord-312119-wzcas4zd	52	1	Thus	thus	RB
cord-312119-wzcas4zd	52	2	,	,	,
cord-312119-wzcas4zd	52	3	blocking	block	VBG
cord-312119-wzcas4zd	52	4	attachment	attachment	NN
cord-312119-wzcas4zd	52	5	of	of	IN
cord-312119-wzcas4zd	52	6	K88	K88	NNP
cord-312119-wzcas4zd	52	7	and	and	CC
cord-312119-wzcas4zd	52	8	F18	F18	NNP
cord-312119-wzcas4zd	52	9	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	52	10	to	to	TO
cord-312119-wzcas4zd	52	11	enterocyte	enterocyte	VB
cord-312119-wzcas4zd	52	12	receptors	receptor	NNS
cord-312119-wzcas4zd	52	13	would	would	MD
cord-312119-wzcas4zd	52	14	be	be	VB
cord-312119-wzcas4zd	52	15	an	an	DT
cord-312119-wzcas4zd	52	16	effective	effective	JJ
cord-312119-wzcas4zd	52	17	means	mean	NNS
cord-312119-wzcas4zd	52	18	to	to	TO
cord-312119-wzcas4zd	52	19	prevent	prevent	VB
cord-312119-wzcas4zd	52	20	ETEC	etec	JJ
cord-312119-wzcas4zd	52	21	colonization	colonization	NN
cord-312119-wzcas4zd	52	22	.	.	.
cord-312119-wzcas4zd	53	1	Neutralizing	neutralize	VBG
cord-312119-wzcas4zd	53	2	epitopes	epitope	NNS
cord-312119-wzcas4zd	53	3	from	from	IN
cord-312119-wzcas4zd	53	4	K88	K88	NNP
cord-312119-wzcas4zd	53	5	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	53	6	adhesin	adhesin	NN
cord-312119-wzcas4zd	53	7	FaeG	FaeG	NNP
cord-312119-wzcas4zd	53	8	(	(	-LRB-
cord-312119-wzcas4zd	53	9	Lu	Lu	NNP
cord-312119-wzcas4zd	53	10	and	and	CC
cord-312119-wzcas4zd	53	11	Zhang	Zhang	NNP
cord-312119-wzcas4zd	53	12	,	,	,
cord-312119-wzcas4zd	53	13	2017	2017	CD
cord-312119-wzcas4zd	53	14	)	)	-RRB-
cord-312119-wzcas4zd	53	15	and	and	CC
cord-312119-wzcas4zd	53	16	toxins	toxin	NNS
cord-312119-wzcas4zd	53	17	including	include	VBG
cord-312119-wzcas4zd	53	18	LT	LT	NNP
cord-312119-wzcas4zd	53	19	(	(	-LRB-
cord-312119-wzcas4zd	53	20	Huang	Huang	NNP
cord-312119-wzcas4zd	53	21	et	et	NNP
cord-312119-wzcas4zd	53	22	al	al	NNP
cord-312119-wzcas4zd	53	23	.	.	NNP
cord-312119-wzcas4zd	53	24	,	,	,
cord-312119-wzcas4zd	53	25	2018	2018	CD
cord-312119-wzcas4zd	53	26	)	)	-RRB-
cord-312119-wzcas4zd	53	27	,	,	,
cord-312119-wzcas4zd	53	28	STa	sta	JJ
cord-312119-wzcas4zd	53	29	(	(	-LRB-
cord-312119-wzcas4zd	53	30	Rausch	Rausch	NNP
cord-312119-wzcas4zd	53	31	et	et	NNP
cord-312119-wzcas4zd	53	32	al	al	NNP
cord-312119-wzcas4zd	53	33	.	.	NNP
cord-312119-wzcas4zd	53	34	,	,	,
cord-312119-wzcas4zd	53	35	2017	2017	CD
cord-312119-wzcas4zd	53	36	;	;	:
cord-312119-wzcas4zd	53	37	Ruan	Ruan	NNP
cord-312119-wzcas4zd	53	38	et	et	NNP
cord-312119-wzcas4zd	53	39	al	al	NNP
cord-312119-wzcas4zd	53	40	.	.	NNP
cord-312119-wzcas4zd	53	41	,	,	,
cord-312119-wzcas4zd	53	42	2014b	2014b	CD
cord-312119-wzcas4zd	53	43	;	;	:
cord-312119-wzcas4zd	53	44	Zhang	Zhang	NNP
cord-312119-wzcas4zd	53	45	et	et	NNP
cord-312119-wzcas4zd	53	46	al	al	NNP
cord-312119-wzcas4zd	53	47	.	.	NNP
cord-312119-wzcas4zd	53	48	,	,	,
cord-312119-wzcas4zd	53	49	2010	2010	CD
cord-312119-wzcas4zd	53	50	)	)	-RRB-
cord-312119-wzcas4zd	53	51	,	,	,
cord-312119-wzcas4zd	53	52	and	and	CC
cord-312119-wzcas4zd	53	53	STb	stb	JJ
cord-312119-wzcas4zd	53	54	(	(	-LRB-
cord-312119-wzcas4zd	53	55	Rausch	Rausch	NNP
cord-312119-wzcas4zd	53	56	et	et	NNP
cord-312119-wzcas4zd	53	57	al	al	NNP
cord-312119-wzcas4zd	53	58	.	.	NNP
cord-312119-wzcas4zd	53	59	,	,	,
cord-312119-wzcas4zd	53	60	2017	2017	CD
cord-312119-wzcas4zd	53	61	)	)	-RRB-
cord-312119-wzcas4zd	53	62	were	be	VBD
cord-312119-wzcas4zd	53	63	identified	identify	VBN
cord-312119-wzcas4zd	53	64	.	.	.
cord-312119-wzcas4zd	54	1	However	however	RB
cord-312119-wzcas4zd	54	2	,	,	,
cord-312119-wzcas4zd	54	3	epitopes	epitope	NNS
cord-312119-wzcas4zd	54	4	from	from	IN
cord-312119-wzcas4zd	54	5	F18	F18	NNP
cord-312119-wzcas4zd	54	6	adhesive	adhesive	NN
cord-312119-wzcas4zd	54	7	subunit	subunit	NN
cord-312119-wzcas4zd	54	8	FedF	FedF	NNP
cord-312119-wzcas4zd	54	9	are	be	VBP
cord-312119-wzcas4zd	54	10	not	not	RB
cord-312119-wzcas4zd	54	11	mapped	map	VBN
cord-312119-wzcas4zd	54	12	and	and	CC
cord-312119-wzcas4zd	54	13	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	54	14	epitopes	epitope	NNS
cord-312119-wzcas4zd	54	15	have	have	VBP
cord-312119-wzcas4zd	54	16	not	not	RB
cord-312119-wzcas4zd	54	17	been	be	VBN
cord-312119-wzcas4zd	54	18	identified	identify	VBN
cord-312119-wzcas4zd	54	19	.	.	.
cord-312119-wzcas4zd	55	1	With	with	IN
cord-312119-wzcas4zd	55	2	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	55	3	epitopes	epitope	NNS
cord-312119-wzcas4zd	55	4	identified	identify	VBN
cord-312119-wzcas4zd	55	5	from	from	IN
cord-312119-wzcas4zd	55	6	all	all	DT
cord-312119-wzcas4zd	55	7	ETEC	etec	JJ
cord-312119-wzcas4zd	55	8	virulence	virulence	NN
cord-312119-wzcas4zd	55	9	determinants	determinant	NNS
cord-312119-wzcas4zd	55	10	,	,	,
cord-312119-wzcas4zd	55	11	we	-PRON-	PRP
cord-312119-wzcas4zd	55	12	should	should	MD
cord-312119-wzcas4zd	55	13	be	be	VB
cord-312119-wzcas4zd	55	14	able	able	JJ
cord-312119-wzcas4zd	55	15	to	to	TO
cord-312119-wzcas4zd	55	16	apply	apply	VB
cord-312119-wzcas4zd	55	17	the	the	DT
cord-312119-wzcas4zd	55	18	MEFA	MEFA	NNP
cord-312119-wzcas4zd	55	19	technology	technology	NN
cord-312119-wzcas4zd	55	20	to	to	TO
cord-312119-wzcas4zd	55	21	develop	develop	VB
cord-312119-wzcas4zd	55	22	a	a	DT
cord-312119-wzcas4zd	55	23	broadly	broadly	RB
cord-312119-wzcas4zd	55	24	protective	protective	JJ
cord-312119-wzcas4zd	55	25	vaccine	vaccine	NN
cord-312119-wzcas4zd	55	26	against	against	IN
cord-312119-wzcas4zd	55	27	PWD	PWD	NNP
cord-312119-wzcas4zd	55	28	.	.	.
cord-312119-wzcas4zd	56	1	In	in	IN
cord-312119-wzcas4zd	56	2	this	this	DT
cord-312119-wzcas4zd	56	3	study	study	NN
cord-312119-wzcas4zd	56	4	,	,	,
cord-312119-wzcas4zd	56	5	we	-PRON-	PRP
cord-312119-wzcas4zd	56	6	in	in	IN
cord-312119-wzcas4zd	56	7	silico	silico	NNS
cord-312119-wzcas4zd	56	8	identified	identify	VBD
cord-312119-wzcas4zd	56	9	immunodominant	immunodominant	JJ
cord-312119-wzcas4zd	56	10	epitopes	epitope	NNS
cord-312119-wzcas4zd	56	11	from	from	IN
cord-312119-wzcas4zd	56	12	F18	F18	NNP
cord-312119-wzcas4zd	56	13	FedF	FedF	NNP
cord-312119-wzcas4zd	56	14	subunit	subunit	NN
cord-312119-wzcas4zd	56	15	,	,	,
cord-312119-wzcas4zd	56	16	fused	fuse	VBN
cord-312119-wzcas4zd	56	17	individual	individual	JJ
cord-312119-wzcas4zd	56	18	epitopes	epitope	NNS
cord-312119-wzcas4zd	56	19	to	to	IN
cord-312119-wzcas4zd	56	20	protein	protein	NN
cord-312119-wzcas4zd	56	21	carrier	carrier	NN
cord-312119-wzcas4zd	56	22	CfaB	CfaB	NNP
cord-312119-wzcas4zd	56	23	(	(	-LRB-
cord-312119-wzcas4zd	56	24	a	a	DT
cord-312119-wzcas4zd	56	25	structural	structural	JJ
cord-312119-wzcas4zd	56	26	subunit	subunit	NN
cord-312119-wzcas4zd	56	27	of	of	IN
cord-312119-wzcas4zd	56	28	heterologous	heterologous	JJ
cord-312119-wzcas4zd	56	29	human	human	JJ
cord-312119-wzcas4zd	56	30	ETEC	ETEC	NNP
cord-312119-wzcas4zd	56	31	fimbria	fimbria	NNP
cord-312119-wzcas4zd	56	32	CFA	CFA	NNP
cord-312119-wzcas4zd	56	33	/	/	SYM
cord-312119-wzcas4zd	56	34	I	I	NNP
cord-312119-wzcas4zd	56	35	)	)	-RRB-
cord-312119-wzcas4zd	56	36	,	,	.
cord-312119-wzcas4zd	57	1	immunized	immunize	VBN
cord-312119-wzcas4zd	57	2	mice	mouse	NNS
cord-312119-wzcas4zd	57	3	with	with	IN
cord-312119-wzcas4zd	57	4	each	each	DT
cord-312119-wzcas4zd	57	5	epitope	epitope	NN
cord-312119-wzcas4zd	57	6	fusion	fusion	NN
cord-312119-wzcas4zd	57	7	protein	protein	NN
cord-312119-wzcas4zd	57	8	,	,	,
cord-312119-wzcas4zd	57	9	measured	measure	VBN
cord-312119-wzcas4zd	57	10	mouse	mouse	NN
cord-312119-wzcas4zd	57	11	anti	anti	JJ
cord-312119-wzcas4zd	57	12	-	-	JJ
cord-312119-wzcas4zd	57	13	F18	f18	JJ
cord-312119-wzcas4zd	57	14	antibody	antibody	NN
cord-312119-wzcas4zd	57	15	response	response	NN
cord-312119-wzcas4zd	57	16	,	,	,
cord-312119-wzcas4zd	57	17	and	and	CC
cord-312119-wzcas4zd	57	18	examined	examine	VBD
cord-312119-wzcas4zd	57	19	epitope	epitope	NN
cord-312119-wzcas4zd	57	20	-	-	HYPH
cord-312119-wzcas4zd	57	21	derived	derive	VBN
cord-312119-wzcas4zd	57	22	antibodies	antibody	NNS
cord-312119-wzcas4zd	57	23	for	for	IN
cord-312119-wzcas4zd	57	24	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	57	25	activities	activity	NNS
cord-312119-wzcas4zd	57	26	against	against	IN
cord-312119-wzcas4zd	57	27	F18	F18	NNP
cord-312119-wzcas4zd	57	28	fimbria	fimbria	NN
cord-312119-wzcas4zd	57	29	adherence	adherence	NN
cord-312119-wzcas4zd	57	30	to	to	TO
cord-312119-wzcas4zd	57	31	determine	determine	VB
cord-312119-wzcas4zd	57	32	FedF	FedF	NNP
cord-312119-wzcas4zd	57	33	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	57	34	epitopes	epitope	NNS
cord-312119-wzcas4zd	57	35	.	.	.
cord-312119-wzcas4zd	58	1	Bacterial	bacterial	JJ
cord-312119-wzcas4zd	58	2	strains	strain	NNS
cord-312119-wzcas4zd	58	3	and	and	CC
cord-312119-wzcas4zd	58	4	plasmids	plasmid	NNS
cord-312119-wzcas4zd	58	5	used	use	VBN
cord-312119-wzcas4zd	58	6	in	in	IN
cord-312119-wzcas4zd	58	7	this	this	DT
cord-312119-wzcas4zd	58	8	study	study	NN
cord-312119-wzcas4zd	58	9	are	be	VBP
cord-312119-wzcas4zd	58	10	listed	list	VBN
cord-312119-wzcas4zd	58	11	in	in	IN
cord-312119-wzcas4zd	58	12	Table	Table	NNP
cord-312119-wzcas4zd	58	13	1	1	CD
cord-312119-wzcas4zd	58	14	.	.	.
cord-312119-wzcas4zd	59	1	Recombinant	recombinant	JJ
cord-312119-wzcas4zd	59	2	CfaB	CfaB	NNP
cord-312119-wzcas4zd	59	3	strain	strain	NN
cord-312119-wzcas4zd	59	4	9477	9477	CD
cord-312119-wzcas4zd	60	1	(	(	-LRB-
cord-312119-wzcas4zd	60	2	Ruan	Ruan	NNP
cord-312119-wzcas4zd	60	3	et	et	NNP
cord-312119-wzcas4zd	60	4	al	al	NNP
cord-312119-wzcas4zd	60	5	.	.	NNP
cord-312119-wzcas4zd	60	6	,	,	,
cord-312119-wzcas4zd	60	7	2015	2015	CD
cord-312119-wzcas4zd	60	8	)	)	-RRB-
cord-312119-wzcas4zd	60	9	were	be	VBD
cord-312119-wzcas4zd	60	10	used	use	VBN
cord-312119-wzcas4zd	60	11	as	as	IN
cord-312119-wzcas4zd	60	12	DNA	dna	NN
cord-312119-wzcas4zd	60	13	templates	template	NNS
cord-312119-wzcas4zd	60	14	for	for	IN
cord-312119-wzcas4zd	60	15	CfaB	CfaB	NNP
cord-312119-wzcas4zd	60	16	gene	gene	NN
cord-312119-wzcas4zd	60	17	PCR	pcr	NN
cord-312119-wzcas4zd	60	18	amplification	amplification	NN
cord-312119-wzcas4zd	60	19	.	.	.
cord-312119-wzcas4zd	61	1	CfaB	cfab	NN
cord-312119-wzcas4zd	61	2	-	-	HYPH
cord-312119-wzcas4zd	61	3	epitope	epitope	NN
cord-312119-wzcas4zd	61	4	fusion	fusion	NN
cord-312119-wzcas4zd	61	5	genes	gene	NNS
cord-312119-wzcas4zd	61	6	were	be	VBD
cord-312119-wzcas4zd	61	7	cloned	clone	VBN
cord-312119-wzcas4zd	61	8	in	in	IN
cord-312119-wzcas4zd	61	9	vector	vector	NN
cord-312119-wzcas4zd	61	10	pET28α	pet28α	NN
cord-312119-wzcas4zd	61	11	(	(	-LRB-
cord-312119-wzcas4zd	61	12	Novagen	Novagen	NNP
cord-312119-wzcas4zd	61	13	,	,	,
cord-312119-wzcas4zd	61	14	Madison	Madison	NNP
cord-312119-wzcas4zd	61	15	,	,	,
cord-312119-wzcas4zd	61	16	WI	WI	NNP
cord-312119-wzcas4zd	61	17	)	)	-RRB-
cord-312119-wzcas4zd	61	18	and	and	CC
cord-312119-wzcas4zd	61	19	expressed	express	VBN
cord-312119-wzcas4zd	61	20	in	in	IN
cord-312119-wzcas4zd	61	21	E.	E.	NNP
cord-312119-wzcas4zd	61	22	coli	coli	NNS
cord-312119-wzcas4zd	61	23	BL21-CodonPlus	bl21-codonplus	CC
cord-312119-wzcas4zd	62	1	(	(	-LRB-
cord-312119-wzcas4zd	62	2	DE3	DE3	NNP
cord-312119-wzcas4zd	62	3	)	)	-RRB-
cord-312119-wzcas4zd	62	4	.	.	.
cord-312119-wzcas4zd	63	1	F18	f18	JJ
cord-312119-wzcas4zd	63	2	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	63	3	E.	E.	NNP
cord-312119-wzcas4zd	63	4	coli	coli	NNS
cord-312119-wzcas4zd	63	5	field	field	NN
cord-312119-wzcas4zd	63	6	isolate	isolate	VBP
cord-312119-wzcas4zd	63	7	8516	8516	CD
cord-312119-wzcas4zd	63	8	was	be	VBD
cord-312119-wzcas4zd	63	9	used	use	VBN
cord-312119-wzcas4zd	63	10	in	in	IN
cord-312119-wzcas4zd	63	11	antibody	antibody	NN
cord-312119-wzcas4zd	63	12	adherence	adherence	NN
cord-312119-wzcas4zd	63	13	inhibition	inhibition	NN
cord-312119-wzcas4zd	63	14	assay	assay	NN
cord-312119-wzcas4zd	63	15	.	.	.
cord-312119-wzcas4zd	64	1	Immunodominant	Immunodominant	NNP
cord-312119-wzcas4zd	64	2	epitopes	epitope	NNS
cord-312119-wzcas4zd	64	3	from	from	IN
cord-312119-wzcas4zd	64	4	F18	F18	NNP
cord-312119-wzcas4zd	64	5	FedF	FedF	NNP
cord-312119-wzcas4zd	64	6	subunit	subunit	NN
cord-312119-wzcas4zd	64	7	protein	protein	NN
cord-312119-wzcas4zd	64	8	was	be	VBD
cord-312119-wzcas4zd	64	9	in	in	IN
cord-312119-wzcas4zd	64	10	silico	silico	NNS
cord-312119-wzcas4zd	64	11	identified	identify	VBN
cord-312119-wzcas4zd	64	12	with	with	IN
cord-312119-wzcas4zd	64	13	B	b	NN
cord-312119-wzcas4zd	64	14	-	-	HYPH
cord-312119-wzcas4zd	64	15	cell	cell	NN
cord-312119-wzcas4zd	64	16	epitope	epitope	NN
cord-312119-wzcas4zd	64	17	prediction	prediction	NN
cord-312119-wzcas4zd	64	18	programs	program	NNS
cord-312119-wzcas4zd	64	19	(	(	-LRB-
cord-312119-wzcas4zd	64	20	Larsen	Larsen	NNP
cord-312119-wzcas4zd	64	21	et	et	NNP
cord-312119-wzcas4zd	64	22	al	al	NNP
cord-312119-wzcas4zd	64	23	.	.	NNP
cord-312119-wzcas4zd	64	24	,	,	,
cord-312119-wzcas4zd	64	25	2006	2006	CD
cord-312119-wzcas4zd	64	26	;	;	:
cord-312119-wzcas4zd	64	27	Saha	Saha	NNP
cord-312119-wzcas4zd	64	28	and	and	CC
cord-312119-wzcas4zd	64	29	Raghava	Raghava	NNP
cord-312119-wzcas4zd	64	30	,	,	,
cord-312119-wzcas4zd	64	31	2007	2007	CD
cord-312119-wzcas4zd	64	32	(	(	-LRB-
cord-312119-wzcas4zd	64	33	Table	table	NN
cord-312119-wzcas4zd	64	34	2	2	CD
cord-312119-wzcas4zd	64	35	)	)	-RRB-
cord-312119-wzcas4zd	64	36	,	,	,
cord-312119-wzcas4zd	64	37	as	as	IN
cord-312119-wzcas4zd	64	38	we	-PRON-	PRP
cord-312119-wzcas4zd	64	39	previously	previously	RB
cord-312119-wzcas4zd	64	40	described	describe	VBD
cord-312119-wzcas4zd	64	41	Huang	Huang	NNP
cord-312119-wzcas4zd	64	42	et	et	FW
cord-312119-wzcas4zd	64	43	al	al	NNP
cord-312119-wzcas4zd	64	44	.	.	NNP
cord-312119-wzcas4zd	64	45	,	,	,
cord-312119-wzcas4zd	64	46	2018	2018	CD
cord-312119-wzcas4zd	64	47	;	;	:
cord-312119-wzcas4zd	64	48	Lu	Lu	NNP
cord-312119-wzcas4zd	64	49	and	and	CC
cord-312119-wzcas4zd	64	50	Zhang	Zhang	NNP
cord-312119-wzcas4zd	64	51	,	,	,
cord-312119-wzcas4zd	64	52	2017	2017	CD
cord-312119-wzcas4zd	64	53	)	)	-RRB-
cord-312119-wzcas4zd	64	54	.	.	.
cord-312119-wzcas4zd	65	1	PCR	PCR	NNP
cord-312119-wzcas4zd	65	2	generated	generate	VBD
cord-312119-wzcas4zd	65	3	CfaB	cfab	NN
cord-312119-wzcas4zd	65	4	-	-	HYPH
cord-312119-wzcas4zd	65	5	epitope	epitope	NN
cord-312119-wzcas4zd	65	6	fusion	fusion	NN
cord-312119-wzcas4zd	65	7	genes	gene	NNS
cord-312119-wzcas4zd	65	8	were	be	VBD
cord-312119-wzcas4zd	65	9	digested	digest	VBN
cord-312119-wzcas4zd	65	10	with	with	IN
cord-312119-wzcas4zd	65	11	NheI	NheI	NNP
cord-312119-wzcas4zd	65	12	and	and	CC
cord-312119-wzcas4zd	65	13	EagI	EagI	NNP
cord-312119-wzcas4zd	65	14	restriction	restriction	NN
cord-312119-wzcas4zd	65	15	enzymes	enzyme	NNS
cord-312119-wzcas4zd	65	16	(	(	-LRB-
cord-312119-wzcas4zd	65	17	New	New	NNP
cord-312119-wzcas4zd	65	18	England	England	NNP
cord-312119-wzcas4zd	65	19	BioLabs	BioLabs	NNP
cord-312119-wzcas4zd	65	20	,	,	,
cord-312119-wzcas4zd	65	21	Ipswich	Ipswich	NNP
cord-312119-wzcas4zd	65	22	,	,	,
cord-312119-wzcas4zd	65	23	MA	MA	NNP
cord-312119-wzcas4zd	65	24	)	)	-RRB-
cord-312119-wzcas4zd	65	25	,	,	,
cord-312119-wzcas4zd	65	26	and	and	CC
cord-312119-wzcas4zd	65	27	were	be	VBD
cord-312119-wzcas4zd	65	28	cloned	clone	VBN
cord-312119-wzcas4zd	65	29	into	into	IN
cord-312119-wzcas4zd	65	30	pET28a	pet28a	JJ
cord-312119-wzcas4zd	65	31	vector	vector	NN
cord-312119-wzcas4zd	65	32	.	.	.
cord-312119-wzcas4zd	66	1	Recombinant	recombinant	JJ
cord-312119-wzcas4zd	66	2	CfaB	CfaB	NNP
cord-312119-wzcas4zd	66	3	-	-	HYPH
cord-312119-wzcas4zd	66	4	epitope	epitope	NN
cord-312119-wzcas4zd	66	5	(	(	-LRB-
cord-312119-wzcas4zd	66	6	CfaB	CfaB	NNP
cord-312119-wzcas4zd	66	7	-	-	HYPH
cord-312119-wzcas4zd	66	8	FedF	FedF	NNP
cord-312119-wzcas4zd	66	9	-	-	HYPH
cord-312119-wzcas4zd	66	10	ep	ep	NNP
cord-312119-wzcas4zd	66	11	)	)	-RRB-
cord-312119-wzcas4zd	66	12	fusion	fusion	NN
cord-312119-wzcas4zd	66	13	proteins	protein	NNS
cord-312119-wzcas4zd	66	14	expressed	express	VBN
cord-312119-wzcas4zd	66	15	by	by	IN
cord-312119-wzcas4zd	66	16	E.	E.	NNP
cord-312119-wzcas4zd	66	17	coli	coli	NNS
cord-312119-wzcas4zd	67	1	BL21	BL21	NNP
cord-312119-wzcas4zd	67	2	(	(	-LRB-
cord-312119-wzcas4zd	67	3	DE3	DE3	NNP
cord-312119-wzcas4zd	67	4	)	)	-RRB-
cord-312119-wzcas4zd	67	5	were	be	VBD
cord-312119-wzcas4zd	67	6	extracted	extract	VBN
cord-312119-wzcas4zd	67	7	with	with	IN
cord-312119-wzcas4zd	67	8	bacterial	bacterial	JJ
cord-312119-wzcas4zd	67	9	protein	protein	NN
cord-312119-wzcas4zd	67	10	extraction	extraction	NN
cord-312119-wzcas4zd	67	11	reagent	reagent	NN
cord-312119-wzcas4zd	67	12	(	(	-LRB-
cord-312119-wzcas4zd	67	13	B	b	NN
cord-312119-wzcas4zd	67	14	-	-	HYPH
cord-312119-wzcas4zd	67	15	PER	per	NN
cord-312119-wzcas4zd	67	16	;	;	:
cord-312119-wzcas4zd	67	17	Thermo	Thermo	NNP
cord-312119-wzcas4zd	67	18	Fisher	Fisher	NNP
cord-312119-wzcas4zd	67	19	Scientific	Scientific	NNP
cord-312119-wzcas4zd	67	20	,	,	,
cord-312119-wzcas4zd	67	21	Rochester	Rochester	NNP
cord-312119-wzcas4zd	67	22	,	,	,
cord-312119-wzcas4zd	67	23	NY	NY	NNP
cord-312119-wzcas4zd	67	24	)	)	-RRB-
cord-312119-wzcas4zd	67	25	and	and	CC
cord-312119-wzcas4zd	67	26	refolded	refolde	VBD
cord-312119-wzcas4zd	67	27	as	as	IN
cord-312119-wzcas4zd	67	28	we	-PRON-	PRP
cord-312119-wzcas4zd	67	29	previously	previously	RB
cord-312119-wzcas4zd	67	30	described	describe	VBD
cord-312119-wzcas4zd	67	31	(	(	-LRB-
cord-312119-wzcas4zd	67	32	Huang	Huang	NNP
cord-312119-wzcas4zd	67	33	et	et	NNP
cord-312119-wzcas4zd	67	34	al	al	NNP
cord-312119-wzcas4zd	67	35	.	.	NNP
cord-312119-wzcas4zd	67	36	,	,	,
cord-312119-wzcas4zd	67	37	2018	2018	CD
cord-312119-wzcas4zd	67	38	;	;	:
cord-312119-wzcas4zd	67	39	Nandre	Nandre	NNP
cord-312119-wzcas4zd	67	40	et	et	IN
cord-312119-wzcas4zd	67	41	al	al	NNP
cord-312119-wzcas4zd	67	42	.	.	NNP
cord-312119-wzcas4zd	67	43	,	,	,
cord-312119-wzcas4zd	67	44	2016	2016	CD
cord-312119-wzcas4zd	67	45	;	;	:
cord-312119-wzcas4zd	67	46	Rausch	Rausch	NNP
cord-312119-wzcas4zd	67	47	et	et	NNP
cord-312119-wzcas4zd	67	48	al	al	NNP
cord-312119-wzcas4zd	67	49	.	.	NNP
cord-312119-wzcas4zd	67	50	,	,	,
cord-312119-wzcas4zd	67	51	2017	2017	CD
cord-312119-wzcas4zd	67	52	)	)	-RRB-
cord-312119-wzcas4zd	67	53	.	.	.
cord-312119-wzcas4zd	68	1	Refolded	refolded	JJ
cord-312119-wzcas4zd	68	2	fusion	fusion	NN
cord-312119-wzcas4zd	68	3	proteins	protein	NNS
cord-312119-wzcas4zd	68	4	were	be	VBD
cord-312119-wzcas4zd	68	5	examined	examine	VBN
cord-312119-wzcas4zd	68	6	in	in	IN
cord-312119-wzcas4zd	68	7	SDS	SDS	NNP
cord-312119-wzcas4zd	68	8	-	-	HYPH
cord-312119-wzcas4zd	68	9	PAGE	PAGE	NNP
cord-312119-wzcas4zd	68	10	with	with	IN
cord-312119-wzcas4zd	68	11	Coomassie	Coomassie	NNP
cord-312119-wzcas4zd	68	12	blue	blue	JJ
cord-312119-wzcas4zd	68	13	staining	staining	NN
cord-312119-wzcas4zd	68	14	,	,	,
cord-312119-wzcas4zd	68	15	and	and	CC
cord-312119-wzcas4zd	68	16	were	be	VBD
cord-312119-wzcas4zd	68	17	characterized	characterize	VBN
cord-312119-wzcas4zd	68	18	in	in	IN
cord-312119-wzcas4zd	68	19	Western	western	JJ
cord-312119-wzcas4zd	68	20	blot	blot	NN
cord-312119-wzcas4zd	68	21	or	or	CC
cord-312119-wzcas4zd	68	22	direct	direct	JJ
cord-312119-wzcas4zd	68	23	ELISAs	elisa	NNS
cord-312119-wzcas4zd	68	24	with	with	IN
cord-312119-wzcas4zd	68	25	anti	anti	JJ
cord-312119-wzcas4zd	68	26	-	-	JJ
cord-312119-wzcas4zd	68	27	F18	f18	JJ
cord-312119-wzcas4zd	68	28	mouse	mouse	NN
cord-312119-wzcas4zd	68	29	antiserum	antiserum	NN
cord-312119-wzcas4zd	68	30	.	.	.
cord-312119-wzcas4zd	69	1	Additionally	additionally	RB
cord-312119-wzcas4zd	69	2	,	,	,
cord-312119-wzcas4zd	69	3	each	each	DT
cord-312119-wzcas4zd	69	4	CfaB	cfab	NN
cord-312119-wzcas4zd	69	5	-	-	HYPH
cord-312119-wzcas4zd	69	6	epitope	epitope	NN
cord-312119-wzcas4zd	69	7	fusion	fusion	NN
cord-312119-wzcas4zd	69	8	protein	protein	NN
cord-312119-wzcas4zd	69	9	was	be	VBD
cord-312119-wzcas4zd	69	10	investigated	investigate	VBN
cord-312119-wzcas4zd	69	11	for	for	IN
cord-312119-wzcas4zd	69	12	blocking	block	VBG
cord-312119-wzcas4zd	69	13	F18	F18	NNP
cord-312119-wzcas4zd	69	14	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	69	15	from	from	IN
cord-312119-wzcas4zd	69	16	reacting	react	VBG
cord-312119-wzcas4zd	69	17	with	with	IN
cord-312119-wzcas4zd	69	18	anti	anti	JJ
cord-312119-wzcas4zd	69	19	-	-	JJ
cord-312119-wzcas4zd	69	20	F18	f18	JJ
cord-312119-wzcas4zd	69	21	antiserum	antiserum	NN
cord-312119-wzcas4zd	69	22	in	in	IN
cord-312119-wzcas4zd	69	23	competitive	competitive	JJ
cord-312119-wzcas4zd	69	24	ELISAs	elisa	NNS
cord-312119-wzcas4zd	69	25	.	.	.
cord-312119-wzcas4zd	70	1	Four	four	CD
cord-312119-wzcas4zd	70	2	μg	μg	XX
cord-312119-wzcas4zd	71	1	CfaB	cfab	NN
cord-312119-wzcas4zd	71	2	-	-	HYPH
cord-312119-wzcas4zd	71	3	epitope	epitope	NN
cord-312119-wzcas4zd	71	4	fusion	fusion	NN
cord-312119-wzcas4zd	71	5	protein	protein	NN
cord-312119-wzcas4zd	71	6	was	be	VBD
cord-312119-wzcas4zd	71	7	incubated	incubate	VBN
cord-312119-wzcas4zd	71	8	with	with	IN
cord-312119-wzcas4zd	71	9	mouse	mouse	NN
cord-312119-wzcas4zd	71	10	anti	anti	JJ
cord-312119-wzcas4zd	71	11	-	-	JJ
cord-312119-wzcas4zd	71	12	F18	f18	JJ
cord-312119-wzcas4zd	71	13	serum	serum	NN
cord-312119-wzcas4zd	71	14	dilutions	dilution	NNS
cord-312119-wzcas4zd	71	15	(	(	-LRB-
cord-312119-wzcas4zd	71	16	1:4,000	1:4,000	CD
cord-312119-wzcas4zd	71	17	to	to	TO
cord-312119-wzcas4zd	71	18	1:32,000	1:32,000	CD
cord-312119-wzcas4zd	71	19	)	)	-RRB-
cord-312119-wzcas4zd	71	20	for	for	IN
cord-312119-wzcas4zd	71	21	30	30	CD
cord-312119-wzcas4zd	71	22	min	min	NN
cord-312119-wzcas4zd	71	23	at	at	IN
cord-312119-wzcas4zd	71	24	room	room	NN
cord-312119-wzcas4zd	71	25	temperature	temperature	NN
cord-312119-wzcas4zd	71	26	.	.	.
cord-312119-wzcas4zd	72	1	Each	each	DT
cord-312119-wzcas4zd	72	2	mixture	mixture	NN
cord-312119-wzcas4zd	72	3	was	be	VBD
cord-312119-wzcas4zd	72	4	added	add	VBN
cord-312119-wzcas4zd	72	5	to	to	IN
cord-312119-wzcas4zd	72	6	ELISA	ELISA	NNP
cord-312119-wzcas4zd	72	7	plate	plate	NN
cord-312119-wzcas4zd	72	8	wells	well	NNS
cord-312119-wzcas4zd	72	9	coated	coat	VBN
cord-312119-wzcas4zd	72	10	with	with	IN
cord-312119-wzcas4zd	72	11	F18	F18	NNP
cord-312119-wzcas4zd	72	12	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	72	13	(	(	-LRB-
cord-312119-wzcas4zd	72	14	50	50	CD
cord-312119-wzcas4zd	72	15	ng	ng	NN
cord-312119-wzcas4zd	72	16	per	per	IN
cord-312119-wzcas4zd	72	17	well	well	NN
cord-312119-wzcas4zd	72	18	)	)	-RRB-
cord-312119-wzcas4zd	72	19	.	.	.
cord-312119-wzcas4zd	73	1	Incubated	incubate	VBN
cord-312119-wzcas4zd	73	2	at	at	IN
cord-312119-wzcas4zd	73	3	37⁰C	37⁰c	CD
cord-312119-wzcas4zd	73	4	for	for	IN
cord-312119-wzcas4zd	73	5	1	1	CD
cord-312119-wzcas4zd	73	6	h	h	NNP
cord-312119-wzcas4zd	73	7	,	,	,
cord-312119-wzcas4zd	73	8	wells	well	NNS
cord-312119-wzcas4zd	73	9	were	be	VBD
cord-312119-wzcas4zd	73	10	washed	wash	VBN
cord-312119-wzcas4zd	73	11	with	with	IN
cord-312119-wzcas4zd	73	12	PBS-0.05	pbs-0.05	JJ
cord-312119-wzcas4zd	73	13	%	%	NN
cord-312119-wzcas4zd	73	14	tween-20	tween-20	CD
cord-312119-wzcas4zd	73	15	(	(	-LRB-
cord-312119-wzcas4zd	73	16	PBST	PBST	NNP
cord-312119-wzcas4zd	73	17	)	)	-RRB-
cord-312119-wzcas4zd	73	18	,	,	,
cord-312119-wzcas4zd	73	19	and	and	CC
cord-312119-wzcas4zd	73	20	incubated	incubate	VBN
cord-312119-wzcas4zd	73	21	with	with	IN
cord-312119-wzcas4zd	73	22	horseradish	horseradish	NN
cord-312119-wzcas4zd	73	23	peroxidase	peroxidase	NN
cord-312119-wzcas4zd	73	24	(	(	-LRB-
cord-312119-wzcas4zd	73	25	HRP)-conjugated	HRP)-conjugated	NNP
cord-312119-wzcas4zd	73	26	goat	goat	NN
cord-312119-wzcas4zd	73	27	-	-	HYPH
cord-312119-wzcas4zd	73	28	anti	anti	JJ
cord-312119-wzcas4zd	73	29	-	-	JJ
cord-312119-wzcas4zd	73	30	mouse	mouse	JJ
cord-312119-wzcas4zd	73	31	IgG	igg	NN
cord-312119-wzcas4zd	73	32	(	(	-LRB-
cord-312119-wzcas4zd	73	33	1:3000	1:3000	CD
cord-312119-wzcas4zd	73	34	;	;	:
cord-312119-wzcas4zd	73	35	Sigma	Sigma	NNP
cord-312119-wzcas4zd	73	36	,	,	,
cord-312119-wzcas4zd	73	37	St.	St.	NNP
cord-312119-wzcas4zd	73	38	Louis	Louis	NNP
cord-312119-wzcas4zd	73	39	,	,	,
cord-312119-wzcas4zd	73	40	MO	MO	NNP
cord-312119-wzcas4zd	73	41	)	)	-RRB-
cord-312119-wzcas4zd	73	42	.	.	.
cord-312119-wzcas4zd	74	1	OD	OD	NNP
cord-312119-wzcas4zd	74	2	600	600	CD
cord-312119-wzcas4zd	74	3	was	be	VBD
cord-312119-wzcas4zd	74	4	measured	measure	VBN
cord-312119-wzcas4zd	74	5	after	after	IN
cord-312119-wzcas4zd	74	6	exposure	exposure	NN
cord-312119-wzcas4zd	74	7	to	to	IN
cord-312119-wzcas4zd	74	8	3,3′,5,5′-tetramethylbenidine	3,3′,5,5′-tetramethylbenidine	CD
cord-312119-wzcas4zd	74	9	(	(	-LRB-
cord-312119-wzcas4zd	74	10	TMB	tmb	NN
cord-312119-wzcas4zd	74	11	;	;	:
cord-312119-wzcas4zd	74	12	KPL	KPL	NNP
cord-312119-wzcas4zd	74	13	,	,	,
cord-312119-wzcas4zd	74	14	Gaithersburg	Gaithersburg	NNP
cord-312119-wzcas4zd	74	15	,	,	,
cord-312119-wzcas4zd	74	16	MD	MD	NNP
cord-312119-wzcas4zd	74	17	)	)	-RRB-
cord-312119-wzcas4zd	74	18	for	for	IN
cord-312119-wzcas4zd	74	19	30	30	CD
cord-312119-wzcas4zd	74	20	min	min	NN
cord-312119-wzcas4zd	74	21	at	at	IN
cord-312119-wzcas4zd	74	22	room	room	NN
cord-312119-wzcas4zd	74	23	temperature	temperature	NN
cord-312119-wzcas4zd	74	24	.	.	.
cord-312119-wzcas4zd	75	1	Furthermore	furthermore	RB
cord-312119-wzcas4zd	75	2	,	,	,
cord-312119-wzcas4zd	75	3	CfaB	cfab	NN
cord-312119-wzcas4zd	75	4	-	-	HYPH
cord-312119-wzcas4zd	75	5	epitope	epitope	NN
cord-312119-wzcas4zd	75	6	fusions	fusion	NNS
cord-312119-wzcas4zd	75	7	were	be	VBD
cord-312119-wzcas4zd	75	8	examined	examine	VBN
cord-312119-wzcas4zd	75	9	as	as	IN
cord-312119-wzcas4zd	75	10	competitive	competitive	JJ
cord-312119-wzcas4zd	75	11	agents	agent	NNS
cord-312119-wzcas4zd	75	12	to	to	TO
cord-312119-wzcas4zd	75	13	prevent	prevent	VB
cord-312119-wzcas4zd	75	14	anti	anti	JJ
cord-312119-wzcas4zd	75	15	-	-	JJ
cord-312119-wzcas4zd	75	16	F18	f18	JJ
cord-312119-wzcas4zd	75	17	antibodies	antibody	NNS
cord-312119-wzcas4zd	75	18	from	from	IN
cord-312119-wzcas4zd	75	19	inhibiting	inhibit	VBG
cord-312119-wzcas4zd	75	20	adherence	adherence	NN
cord-312119-wzcas4zd	75	21	of	of	IN
cord-312119-wzcas4zd	75	22	F18fimbrial	f18fimbrial	JJ
cord-312119-wzcas4zd	75	23	bacteria	bacteria	NNS
cord-312119-wzcas4zd	75	24	to	to	IN
cord-312119-wzcas4zd	75	25	pig	pig	NN
cord-312119-wzcas4zd	75	26	intestine	intestine	NN
cord-312119-wzcas4zd	75	27	cell	cell	NN
cord-312119-wzcas4zd	75	28	line	line	NN
cord-312119-wzcas4zd	75	29	IPEC-2	ipec-2	NN
cord-312119-wzcas4zd	75	30	.	.	.
cord-312119-wzcas4zd	76	1	Since	since	IN
cord-312119-wzcas4zd	76	2	protective	protective	JJ
cord-312119-wzcas4zd	76	3	anti	anti	JJ
cord-312119-wzcas4zd	76	4	-	-	JJ
cord-312119-wzcas4zd	76	5	F18	f18	JJ
cord-312119-wzcas4zd	76	6	antibodies	antibody	NNS
cord-312119-wzcas4zd	76	7	inhibit	inhibit	VBP
cord-312119-wzcas4zd	76	8	adherence	adherence	NN
cord-312119-wzcas4zd	76	9	of	of	IN
cord-312119-wzcas4zd	76	10	F18-fimbiral	F18-fimbiral	NNP
cord-312119-wzcas4zd	76	11	E.	E.	NNP
cord-312119-wzcas4zd	76	12	coli	coli	NNS
cord-312119-wzcas4zd	76	13	to	to	TO
cord-312119-wzcas4zd	76	14	host	host	VB
cord-312119-wzcas4zd	76	15	receptors	receptor	NNS
cord-312119-wzcas4zd	76	16	,	,	,
cord-312119-wzcas4zd	76	17	conformational	conformational	JJ
cord-312119-wzcas4zd	76	18	F18	f18	JJ
cord-312119-wzcas4zd	76	19	epitopes	epitope	NNS
cord-312119-wzcas4zd	76	20	react	react	VBP
cord-312119-wzcas4zd	76	21	with	with	IN
cord-312119-wzcas4zd	76	22	anti	anti	JJ
cord-312119-wzcas4zd	76	23	-	-	JJ
cord-312119-wzcas4zd	76	24	F18	f18	JJ
cord-312119-wzcas4zd	76	25	antibodies	antibody	NNS
cord-312119-wzcas4zd	76	26	(	(	-LRB-
cord-312119-wzcas4zd	76	27	derived	derive	VBN
cord-312119-wzcas4zd	76	28	from	from	IN
cord-312119-wzcas4zd	76	29	F18	F18	NNP
cord-312119-wzcas4zd	76	30	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	76	31	)	)	-RRB-
cord-312119-wzcas4zd	76	32	thus	thus	RB
cord-312119-wzcas4zd	76	33	abolish	abolish	VB
cord-312119-wzcas4zd	76	34	antibodies	antibody	NNS
cord-312119-wzcas4zd	76	35	from	from	IN
cord-312119-wzcas4zd	76	36	adherence	adherence	NN
cord-312119-wzcas4zd	76	37	inhibition	inhibition	NN
cord-312119-wzcas4zd	76	38	.	.	.
cord-312119-wzcas4zd	77	1	Nearly	nearly	RB
cord-312119-wzcas4zd	77	2	identical	identical	JJ
cord-312119-wzcas4zd	77	3	to	to	IN
cord-312119-wzcas4zd	77	4	antibody	antibody	NN
cord-312119-wzcas4zd	77	5	adherence	adherence	NN
cord-312119-wzcas4zd	77	6	inhibition	inhibition	NN
cord-312119-wzcas4zd	77	7	assay	assay	NN
cord-312119-wzcas4zd	77	8	previously	previously	RB
cord-312119-wzcas4zd	77	9	described	describe	VBD
cord-312119-wzcas4zd	77	10	(	(	-LRB-
cord-312119-wzcas4zd	77	11	Rausch	Rausch	NNP
cord-312119-wzcas4zd	77	12	et	et	NNP
cord-312119-wzcas4zd	77	13	al	al	NNP
cord-312119-wzcas4zd	77	14	.	.	NNP
cord-312119-wzcas4zd	77	15	,	,	,
cord-312119-wzcas4zd	77	16	2017	2017	CD
cord-312119-wzcas4zd	77	17	;	;	:
cord-312119-wzcas4zd	77	18	Ruan	Ruan	NNP
cord-312119-wzcas4zd	77	19	and	and	CC
cord-312119-wzcas4zd	77	20	Zhang	Zhang	NNP
cord-312119-wzcas4zd	77	21	,	,	,
cord-312119-wzcas4zd	77	22	2013	2013	CD
cord-312119-wzcas4zd	77	23	Ruan	Ruan	NNP
cord-312119-wzcas4zd	77	24	et	et	NNP
cord-312119-wzcas4zd	77	25	al	al	NNP
cord-312119-wzcas4zd	77	26	.	.	NNP
cord-312119-wzcas4zd	77	27	,	,	,
cord-312119-wzcas4zd	77	28	2014a	2014a	CD
cord-312119-wzcas4zd	77	29	,	,	,
cord-312119-wzcas4zd	77	30	2011	2011	CD
cord-312119-wzcas4zd	77	31	,	,	,
cord-312119-wzcas4zd	77	32	except	except	IN
cord-312119-wzcas4zd	77	33	the	the	DT
cord-312119-wzcas4zd	77	34	addition	addition	NN
cord-312119-wzcas4zd	77	35	of	of	IN
cord-312119-wzcas4zd	77	36	CfaB	cfab	NN
cord-312119-wzcas4zd	77	37	-	-	HYPH
cord-312119-wzcas4zd	77	38	epitope	epitope	NN
cord-312119-wzcas4zd	77	39	fusions	fusion	NNS
cord-312119-wzcas4zd	77	40	as	as	IN
cord-312119-wzcas4zd	77	41	the	the	DT
cord-312119-wzcas4zd	77	42	competitive	competitive	JJ
cord-312119-wzcas4zd	77	43	agent	agent	NN
cord-312119-wzcas4zd	77	44	,	,	,
cord-312119-wzcas4zd	77	45	this	this	DT
cord-312119-wzcas4zd	77	46	assay	assay	NN
cord-312119-wzcas4zd	77	47	measured	measure	VBD
cord-312119-wzcas4zd	77	48	interference	interference	NN
cord-312119-wzcas4zd	77	49	of	of	IN
cord-312119-wzcas4zd	77	50	CfaB	cfab	NN
cord-312119-wzcas4zd	77	51	-	-	HYPH
cord-312119-wzcas4zd	77	52	epitope	epitope	NN
cord-312119-wzcas4zd	77	53	fusion	fusion	NN
cord-312119-wzcas4zd	77	54	protein	protein	NN
cord-312119-wzcas4zd	77	55	to	to	IN
cord-312119-wzcas4zd	77	56	anti	anti	JJ
cord-312119-wzcas4zd	77	57	-	-	JJ
cord-312119-wzcas4zd	77	58	F18	f18	JJ
cord-312119-wzcas4zd	77	59	antibodies	antibody	NNS
cord-312119-wzcas4zd	77	60	in	in	IN
cord-312119-wzcas4zd	77	61	inhibiting	inhibit	VBG
cord-312119-wzcas4zd	77	62	F18	F18	NNP
cord-312119-wzcas4zd	77	63	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	77	64	adherence	adherence	NN
cord-312119-wzcas4zd	77	65	to	to	TO
cord-312119-wzcas4zd	77	66	target	target	VB
cord-312119-wzcas4zd	77	67	host	host	NN
cord-312119-wzcas4zd	77	68	cells	cell	NNS
cord-312119-wzcas4zd	77	69	.	.	.
cord-312119-wzcas4zd	78	1	Ten	ten	CD
cord-312119-wzcas4zd	78	2	ug	ug	NNP
cord-312119-wzcas4zd	78	3	CfaB	CfaB	NNP
cord-312119-wzcas4zd	78	4	-	-	HYPH
cord-312119-wzcas4zd	78	5	epitope	epitope	NN
cord-312119-wzcas4zd	78	6	fusion	fusion	NN
cord-312119-wzcas4zd	78	7	protein	protein	NN
cord-312119-wzcas4zd	78	8	together	together	RB
cord-312119-wzcas4zd	78	9	with	with	IN
cord-312119-wzcas4zd	78	10	1.5	1.5	CD
cord-312119-wzcas4zd	78	11	×	×	NN
cord-312119-wzcas4zd	78	12	10	10	CD
cord-312119-wzcas4zd	78	13	6	6	CD
cord-312119-wzcas4zd	79	1	CFU	CFU	NNP
cord-312119-wzcas4zd	79	2	F18-fimbrial	F18-fimbrial	NNP
cord-312119-wzcas4zd	79	3	E.	E.	NNP
cord-312119-wzcas4zd	79	4	coli	coli	NNS
cord-312119-wzcas4zd	79	5	bacteria	bacteria	NNS
cord-312119-wzcas4zd	79	6	8516	8516	CD
cord-312119-wzcas4zd	79	7	were	be	VBD
cord-312119-wzcas4zd	79	8	mixed	mix	VBN
cord-312119-wzcas4zd	79	9	with	with	IN
cord-312119-wzcas4zd	79	10	25	25	CD
cord-312119-wzcas4zd	79	11	μl	μl	IN
cord-312119-wzcas4zd	79	12	mouse	mouse	NN
cord-312119-wzcas4zd	79	13	anti	anti	JJ
cord-312119-wzcas4zd	79	14	-	-	JJ
cord-312119-wzcas4zd	79	15	F18	f18	JJ
cord-312119-wzcas4zd	79	16	antiserum	antiserum	NN
cord-312119-wzcas4zd	79	17	and	and	CC
cord-312119-wzcas4zd	79	18	incubated	incubate	VBN
cord-312119-wzcas4zd	79	19	at	at	IN
cord-312119-wzcas4zd	79	20	room	room	NN
cord-312119-wzcas4zd	79	21	temperature	temperature	NN
cord-312119-wzcas4zd	79	22	for	for	IN
cord-312119-wzcas4zd	79	23	 	 	_SP
cord-312119-wzcas4zd	79	24	Each	each	DT
cord-312119-wzcas4zd	79	25	CfaB	CfaB	NNP
cord-312119-wzcas4zd	79	26	-	-	HYPH
cord-312119-wzcas4zd	79	27	epitope	epitope	NN
cord-312119-wzcas4zd	79	28	fusion	fusion	NN
cord-312119-wzcas4zd	79	29	protein	protein	NN
cord-312119-wzcas4zd	79	30	was	be	VBD
cord-312119-wzcas4zd	79	31	used	use	VBN
cord-312119-wzcas4zd	79	32	to	to	TO
cord-312119-wzcas4zd	79	33	subcutaneously	subcutaneously	RB
cord-312119-wzcas4zd	79	34	immunize	immunize	VB
cord-312119-wzcas4zd	79	35	mice	mouse	NNS
cord-312119-wzcas4zd	79	36	.	.	.
cord-312119-wzcas4zd	80	1	A	a	DT
cord-312119-wzcas4zd	80	2	group	group	NN
cord-312119-wzcas4zd	80	3	of	of	IN
cord-312119-wzcas4zd	80	4	five	five	CD
cord-312119-wzcas4zd	80	5	8-week	8-week	CD
cord-312119-wzcas4zd	80	6	old	old	JJ
cord-312119-wzcas4zd	80	7	female	female	JJ
cord-312119-wzcas4zd	80	8	BALB	BALB	NNP
cord-312119-wzcas4zd	80	9	/	/	SYM
cord-312119-wzcas4zd	80	10	c	c	NN
cord-312119-wzcas4zd	80	11	mice	mouse	NNS
cord-312119-wzcas4zd	80	12	was	be	VBD
cord-312119-wzcas4zd	80	13	each	each	DT
cord-312119-wzcas4zd	80	14	administered	administer	VBN
cord-312119-wzcas4zd	80	15	with	with	IN
cord-312119-wzcas4zd	80	16	40	40	CD
cord-312119-wzcas4zd	80	17	μg	μg	NNP
cord-312119-wzcas4zd	80	18	CfaB	CfaB	NNP
cord-312119-wzcas4zd	80	19	-	-	HYPH
cord-312119-wzcas4zd	80	20	epitope	epitope	NN
cord-312119-wzcas4zd	80	21	fusion	fusion	NN
cord-312119-wzcas4zd	80	22	protein	protein	NN
cord-312119-wzcas4zd	80	23	(	(	-LRB-
cord-312119-wzcas4zd	80	24	in	in	IN
cord-312119-wzcas4zd	80	25	25	25	CD
cord-312119-wzcas4zd	80	26	μl	μl	NNS
cord-312119-wzcas4zd	80	27	)	)	-RRB-
cord-312119-wzcas4zd	80	28	,	,	,
cord-312119-wzcas4zd	80	29	adjuvanted	adjuvante	VBN
cord-312119-wzcas4zd	80	30	with	with	IN
cord-312119-wzcas4zd	80	31	1	1	CD
cord-312119-wzcas4zd	80	32	μg	μg	NNP
cord-312119-wzcas4zd	80	33	dmLT	dmLT	NNP
cord-312119-wzcas4zd	80	34	(	(	-LRB-
cord-312119-wzcas4zd	80	35	double	double	JJ
cord-312119-wzcas4zd	80	36	mutant	mutant	JJ
cord-312119-wzcas4zd	80	37	LT	LT	NNP
cord-312119-wzcas4zd	80	38	,	,	,
cord-312119-wzcas4zd	80	39	LT	LT	NNP
cord-312119-wzcas4zd	80	40	R192G	R192G	NNP
cord-312119-wzcas4zd	80	41	/	/	SYM
cord-312119-wzcas4zd	80	42	L211A	L211A	NNP
cord-312119-wzcas4zd	80	43	;	;	:
cord-312119-wzcas4zd	80	44	provided	provide	VBN
cord-312119-wzcas4zd	80	45	by	by	IN
cord-312119-wzcas4zd	80	46	PATH	path	NN
cord-312119-wzcas4zd	80	47	)	)	-RRB-
cord-312119-wzcas4zd	80	48	.	.	.
cord-312119-wzcas4zd	81	1	Immunized	immunized	JJ
cord-312119-wzcas4zd	81	2	mice	mouse	NNS
cord-312119-wzcas4zd	81	3	received	receive	VBD
cord-312119-wzcas4zd	81	4	two	two	CD
cord-312119-wzcas4zd	81	5	boosters	booster	NNS
cord-312119-wzcas4zd	81	6	of	of	IN
cord-312119-wzcas4zd	81	7	the	the	DT
cord-312119-wzcas4zd	81	8	primary	primary	JJ
cord-312119-wzcas4zd	81	9	dose	dose	NN
cord-312119-wzcas4zd	81	10	at	at	IN
cord-312119-wzcas4zd	81	11	the	the	DT
cord-312119-wzcas4zd	81	12	interval	interval	NN
cord-312119-wzcas4zd	81	13	of	of	IN
cord-312119-wzcas4zd	81	14	two	two	CD
cord-312119-wzcas4zd	81	15	weeks	week	NNS
cord-312119-wzcas4zd	81	16	.	.	.
cord-312119-wzcas4zd	82	1	A	a	DT
cord-312119-wzcas4zd	82	2	group	group	NN
cord-312119-wzcas4zd	82	3	of	of	IN
cord-312119-wzcas4zd	82	4	mice	mouse	NNS
cord-312119-wzcas4zd	82	5	without	without	IN
cord-312119-wzcas4zd	82	6	injection	injection	NN
cord-312119-wzcas4zd	82	7	was	be	VBD
cord-312119-wzcas4zd	82	8	used	use	VBN
cord-312119-wzcas4zd	82	9	as	as	IN
cord-312119-wzcas4zd	82	10	the	the	DT
cord-312119-wzcas4zd	82	11	negative	negative	JJ
cord-312119-wzcas4zd	82	12	control	control	NN
cord-312119-wzcas4zd	82	13	.	.	.
cord-312119-wzcas4zd	83	1	Mouse	mouse	NN
cord-312119-wzcas4zd	83	2	serum	serum	NN
cord-312119-wzcas4zd	83	3	samples	sample	NNS
cord-312119-wzcas4zd	83	4	collected	collect	VBN
cord-312119-wzcas4zd	83	5	before	before	IN
cord-312119-wzcas4zd	83	6	the	the	DT
cord-312119-wzcas4zd	83	7	primary	primary	NN
cord-312119-wzcas4zd	83	8	and	and	CC
cord-312119-wzcas4zd	83	9	two	two	CD
cord-312119-wzcas4zd	83	10	weeks	week	NNS
cord-312119-wzcas4zd	83	11	after	after	IN
cord-312119-wzcas4zd	83	12	the	the	DT
cord-312119-wzcas4zd	83	13	final	final	JJ
cord-312119-wzcas4zd	83	14	booster	booster	NN
cord-312119-wzcas4zd	83	15	were	be	VBD
cord-312119-wzcas4zd	83	16	used	use	VBN
cord-312119-wzcas4zd	83	17	to	to	TO
cord-312119-wzcas4zd	83	18	prepare	prepare	VB
cord-312119-wzcas4zd	83	19	serum	serum	NN
cord-312119-wzcas4zd	83	20	samples	sample	NNS
cord-312119-wzcas4zd	83	21	.	.	.
cord-312119-wzcas4zd	84	1	Mouse	mouse	NN
cord-312119-wzcas4zd	84	2	serum	serum	NN
cord-312119-wzcas4zd	84	3	samples	sample	NNS
cord-312119-wzcas4zd	84	4	were	be	VBD
cord-312119-wzcas4zd	84	5	stored	store	VBN
cord-312119-wzcas4zd	84	6	at	at	IN
cord-312119-wzcas4zd	84	7	-80⁰C	-80⁰c	NN
cord-312119-wzcas4zd	84	8	until	until	IN
cord-312119-wzcas4zd	84	9	use	use	NN
cord-312119-wzcas4zd	84	10	.	.	.
cord-312119-wzcas4zd	85	1	Mouse	mouse	NN
cord-312119-wzcas4zd	85	2	immunization	immunization	NN
cord-312119-wzcas4zd	85	3	complied	comply	VBD
cord-312119-wzcas4zd	85	4	with	with	IN
cord-312119-wzcas4zd	85	5	Animal	Animal	NNP
cord-312119-wzcas4zd	85	6	Welfare	Welfare	NNP
cord-312119-wzcas4zd	85	7	Act	Act	NNP
cord-312119-wzcas4zd	85	8	under	under	IN
cord-312119-wzcas4zd	85	9	1996	1996	CD
cord-312119-wzcas4zd	85	10	National	National	NNP
cord-312119-wzcas4zd	85	11	Research	Research	NNP
cord-312119-wzcas4zd	85	12	Council	Council	NNP
cord-312119-wzcas4zd	85	13	Guidance	Guidance	NNP
cord-312119-wzcas4zd	85	14	and	and	CC
cord-312119-wzcas4zd	85	15	was	be	VBD
cord-312119-wzcas4zd	85	16	approved	approve	VBN
cord-312119-wzcas4zd	85	17	by	by	IN
cord-312119-wzcas4zd	85	18	Kansas	Kansas	NNP
cord-312119-wzcas4zd	85	19	State	State	NNP
cord-312119-wzcas4zd	85	20	University	University	NNP
cord-312119-wzcas4zd	85	21	Institutional	Institutional	NNP
cord-312119-wzcas4zd	85	22	Animal	Animal	NNP
cord-312119-wzcas4zd	85	23	Care	Care	NNP
cord-312119-wzcas4zd	85	24	and	and	CC
cord-312119-wzcas4zd	85	25	Use	Use	NNP
cord-312119-wzcas4zd	85	26	committee	committee	NN
cord-312119-wzcas4zd	85	27	(	(	-LRB-
cord-312119-wzcas4zd	85	28	protocol	protocol	NN
cord-312119-wzcas4zd	85	29	#	#	$
cord-312119-wzcas4zd	85	30	3879	3879	CD
cord-312119-wzcas4zd	85	31	)	)	-RRB-
cord-312119-wzcas4zd	85	32	.	.	.
cord-312119-wzcas4zd	86	1	Serum	serum	NN
cord-312119-wzcas4zd	86	2	samples	sample	NNS
cord-312119-wzcas4zd	86	3	from	from	IN
cord-312119-wzcas4zd	86	4	each	each	DT
cord-312119-wzcas4zd	86	5	immunized	immunize	VBN
cord-312119-wzcas4zd	86	6	or	or	CC
cord-312119-wzcas4zd	86	7	control	control	NN
cord-312119-wzcas4zd	86	8	mouse	mouse	NN
cord-312119-wzcas4zd	86	9	were	be	VBD
cord-312119-wzcas4zd	86	10	titrated	titrate	VBN
cord-312119-wzcas4zd	86	11	for	for	IN
cord-312119-wzcas4zd	86	12	anti	anti	JJ
cord-312119-wzcas4zd	86	13	-	-	JJ
cord-312119-wzcas4zd	86	14	F18	f18	JJ
cord-312119-wzcas4zd	86	15	IgG	igg	NN
cord-312119-wzcas4zd	86	16	antibodies	antibody	NNS
cord-312119-wzcas4zd	86	17	as	as	IN
cord-312119-wzcas4zd	86	18	we	-PRON-	PRP
cord-312119-wzcas4zd	86	19	previously	previously	RB
cord-312119-wzcas4zd	86	20	described	describe	VBD
cord-312119-wzcas4zd	86	21	(	(	-LRB-
cord-312119-wzcas4zd	86	22	Rausch	Rausch	NNP
cord-312119-wzcas4zd	86	23	et	et	NNP
cord-312119-wzcas4zd	86	24	al	al	NNP
cord-312119-wzcas4zd	86	25	.	.	NNP
cord-312119-wzcas4zd	86	26	,	,	,
cord-312119-wzcas4zd	86	27	2017	2017	CD
cord-312119-wzcas4zd	86	28	;	;	:
cord-312119-wzcas4zd	86	29	Ruan	Ruan	NNP
cord-312119-wzcas4zd	86	30	and	and	CC
cord-312119-wzcas4zd	86	31	Zhang	Zhang	NNP
cord-312119-wzcas4zd	86	32	,	,	,
cord-312119-wzcas4zd	86	33	2013	2013	CD
cord-312119-wzcas4zd	86	34	;	;	:
cord-312119-wzcas4zd	86	35	Ruan	Ruan	NNP
cord-312119-wzcas4zd	86	36	et	et	NNP
cord-312119-wzcas4zd	86	37	al	al	NNP
cord-312119-wzcas4zd	86	38	.	.	NNP
cord-312119-wzcas4zd	86	39	,	,	,
cord-312119-wzcas4zd	86	40	2011	2011	CD
cord-312119-wzcas4zd	86	41	)	)	-RRB-
cord-312119-wzcas4zd	86	42	.	.	.
cord-312119-wzcas4zd	87	1	Briefly	briefly	RB
cord-312119-wzcas4zd	87	2	,	,	,
cord-312119-wzcas4zd	87	3	wells	well	NNS
cord-312119-wzcas4zd	87	4	of	of	IN
cord-312119-wzcas4zd	87	5	2HB	2hb	CD
cord-312119-wzcas4zd	87	6	plates	plate	NNS
cord-312119-wzcas4zd	87	7	(	(	-LRB-
cord-312119-wzcas4zd	87	8	Fisher	Fisher	NNP
cord-312119-wzcas4zd	87	9	Scientific	Scientific	NNP
cord-312119-wzcas4zd	87	10	)	)	-RRB-
cord-312119-wzcas4zd	87	11	coated	coat	VBD
cord-312119-wzcas4zd	87	12	with	with	IN
cord-312119-wzcas4zd	87	13	heat	heat	NN
cord-312119-wzcas4zd	87	14	-	-	HYPH
cord-312119-wzcas4zd	87	15	extracted	extract	VBN
cord-312119-wzcas4zd	87	16	F18	F18	NNP
cord-312119-wzcas4zd	87	17	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	87	18	(	(	-LRB-
cord-312119-wzcas4zd	87	19	100	100	CD
cord-312119-wzcas4zd	87	20	ng	ng	NN
cord-312119-wzcas4zd	87	21	per	per	IN
cord-312119-wzcas4zd	87	22	well	well	NN
cord-312119-wzcas4zd	87	23	)	)	-RRB-
cord-312119-wzcas4zd	87	24	were	be	VBD
cord-312119-wzcas4zd	87	25	incubated	incubate	VBN
cord-312119-wzcas4zd	87	26	with	with	IN
cord-312119-wzcas4zd	87	27	mouse	mouse	NN
cord-312119-wzcas4zd	87	28	serum	serum	NN
cord-312119-wzcas4zd	87	29	binary	binary	JJ
cord-312119-wzcas4zd	87	30	dilutions	dilution	NNS
cord-312119-wzcas4zd	87	31	(	(	-LRB-
cord-312119-wzcas4zd	87	32	1:400	1:400	CD
cord-312119-wzcas4zd	87	33	to	to	IN
cord-312119-wzcas4zd	87	34	1:128,000	1:128,000	CD
cord-312119-wzcas4zd	87	35	)	)	-RRB-
cord-312119-wzcas4zd	87	36	as	as	IN
cord-312119-wzcas4zd	87	37	primary	primary	JJ
cord-312119-wzcas4zd	87	38	antibodies	antibody	NNS
cord-312119-wzcas4zd	87	39	and	and	CC
cord-312119-wzcas4zd	87	40	then	then	RB
cord-312119-wzcas4zd	87	41	HRP	HRP	NNP
cord-312119-wzcas4zd	87	42	-	-	HYPH
cord-312119-wzcas4zd	87	43	conjugated	conjugate	VBN
cord-312119-wzcas4zd	87	44	goat	goat	NN
cord-312119-wzcas4zd	87	45	-	-	HYPH
cord-312119-wzcas4zd	87	46	anti	anti	JJ
cord-312119-wzcas4zd	87	47	-	-	JJ
cord-312119-wzcas4zd	87	48	mouse	mouse	JJ
cord-312119-wzcas4zd	87	49	IgG	igg	NN
cord-312119-wzcas4zd	87	50	(	(	-LRB-
cord-312119-wzcas4zd	87	51	1:3000	1:3000	CD
cord-312119-wzcas4zd	87	52	)	)	-RRB-
cord-312119-wzcas4zd	88	1	as	as	IN
cord-312119-wzcas4zd	88	2	secondary	secondary	JJ
cord-312119-wzcas4zd	88	3	antibodies	antibody	NNS
cord-312119-wzcas4zd	88	4	.	.	.
cord-312119-wzcas4zd	89	1	OD	OD	NNP
cord-312119-wzcas4zd	89	2	650	650	CD
cord-312119-wzcas4zd	89	3	measured	measure	VBD
cord-312119-wzcas4zd	89	4	after	after	IN
cord-312119-wzcas4zd	89	5	exposure	exposure	NN
cord-312119-wzcas4zd	89	6	to	to	IN
cord-312119-wzcas4zd	89	7	TMB	TMB	NNP
cord-312119-wzcas4zd	89	8	were	be	VBD
cord-312119-wzcas4zd	89	9	converted	convert	VBN
cord-312119-wzcas4zd	89	10	to	to	IN
cord-312119-wzcas4zd	89	11	antibody	antibody	NN
cord-312119-wzcas4zd	89	12	titers	titer	NNS
cord-312119-wzcas4zd	89	13	,	,	,
cord-312119-wzcas4zd	89	14	in	in	IN
cord-312119-wzcas4zd	89	15	a	a	DT
cord-312119-wzcas4zd	89	16	log	log	NN
cord-312119-wzcas4zd	89	17	10	10	CD
cord-312119-wzcas4zd	89	18	scale	scale	NN
cord-312119-wzcas4zd	89	19	.	.	.
cord-312119-wzcas4zd	90	1	Mouse	mouse	NN
cord-312119-wzcas4zd	90	2	serum	serum	NN
cord-312119-wzcas4zd	90	3	samples	sample	NNS
cord-312119-wzcas4zd	90	4	from	from	IN
cord-312119-wzcas4zd	90	5	the	the	DT
cord-312119-wzcas4zd	90	6	groups	group	NNS
cord-312119-wzcas4zd	90	7	immunized	immunize	VBN
cord-312119-wzcas4zd	90	8	with	with	IN
cord-312119-wzcas4zd	90	9	each	each	DT
cord-312119-wzcas4zd	90	10	CfaBepitope	CfaBepitope	NNP
cord-312119-wzcas4zd	90	11	fusion	fusion	NN
cord-312119-wzcas4zd	90	12	were	be	VBD
cord-312119-wzcas4zd	90	13	examined	examine	VBN
cord-312119-wzcas4zd	90	14	for	for	IN
cord-312119-wzcas4zd	90	15	antibody	antibody	NN
cord-312119-wzcas4zd	90	16	adherence	adherence	NN
cord-312119-wzcas4zd	90	17	inhibition	inhibition	NN
cord-312119-wzcas4zd	90	18	using	use	VBG
cord-312119-wzcas4zd	90	19	F18-fimbrial	F18-fimbrial	NNP
cord-312119-wzcas4zd	90	20	E.	E.	NNP
cord-312119-wzcas4zd	90	21	coli	coli	NNS
cord-312119-wzcas4zd	90	22	bacteria	bacteria	NNS
cord-312119-wzcas4zd	90	23	8516	8516	CD
cord-312119-wzcas4zd	90	24	and	and	CC
cord-312119-wzcas4zd	90	25	IPEC	IPEC	NNP
cord-312119-wzcas4zd	90	26	-	-	HYPH
cord-312119-wzcas4zd	90	27	J2	j2	NN
cord-312119-wzcas4zd	90	28	cells	cell	NNS
cord-312119-wzcas4zd	90	29	.	.	.
cord-312119-wzcas4zd	91	1	Briefly	briefly	RB
cord-312119-wzcas4zd	91	2	,	,	,
cord-312119-wzcas4zd	91	3	3	3	CD
cord-312119-wzcas4zd	91	4	×	×	NN
cord-312119-wzcas4zd	91	5	10	10	CD
cord-312119-wzcas4zd	91	6	6	6	CD
cord-312119-wzcas4zd	91	7	(	(	-LRB-
cord-312119-wzcas4zd	91	8	CFUs	CFUs	NNP
cord-312119-wzcas4zd	91	9	)	)	-RRB-
cord-312119-wzcas4zd	91	10	bacteria	bacteria	NNS
cord-312119-wzcas4zd	91	11	8516	8516	CD
cord-312119-wzcas4zd	91	12	exposed	expose	VBN
cord-312119-wzcas4zd	91	13	to	to	IN
cord-312119-wzcas4zd	91	14	30	30	CD
cord-312119-wzcas4zd	91	15	μl	μl	NN
cord-312119-wzcas4zd	91	16	serum	serum	NN
cord-312119-wzcas4zd	91	17	pooled	pool	VBN
cord-312119-wzcas4zd	91	18	from	from	IN
cord-312119-wzcas4zd	91	19	each	each	DT
cord-312119-wzcas4zd	91	20	immunization	immunization	NN
cord-312119-wzcas4zd	91	21	group	group	NN
cord-312119-wzcas4zd	91	22	or	or	CC
cord-312119-wzcas4zd	91	23	the	the	DT
cord-312119-wzcas4zd	91	24	control	control	NN
cord-312119-wzcas4zd	91	25	group	group	NN
cord-312119-wzcas4zd	91	26	were	be	VBD
cord-312119-wzcas4zd	91	27	added	add	VBN
cord-312119-wzcas4zd	91	28	to	to	IN
cord-312119-wzcas4zd	91	29	IPEC	IPEC	NNP
cord-312119-wzcas4zd	91	30	-	-	HYPH
cord-312119-wzcas4zd	91	31	J2	j2	NN
cord-312119-wzcas4zd	91	32	cell	cell	NN
cord-312119-wzcas4zd	91	33	(	(	-LRB-
cord-312119-wzcas4zd	91	34	1.5	1.5	CD
cord-312119-wzcas4zd	91	35	×	×	NN
cord-312119-wzcas4zd	91	36	10	10	CD
cord-312119-wzcas4zd	91	37	5	5	CD
cord-312119-wzcas4zd	91	38	per	per	IN
cord-312119-wzcas4zd	91	39	well	well	RB
cord-312119-wzcas4zd	91	40	)	)	-RRB-
cord-312119-wzcas4zd	91	41	and	and	CC
cord-312119-wzcas4zd	91	42	cultured	culture	VBN
cord-312119-wzcas4zd	91	43	for	for	IN
cord-312119-wzcas4zd	91	44	1	1	CD
cord-312119-wzcas4zd	91	45	h	h	NN
cord-312119-wzcas4zd	91	46	in	in	IN
cord-312119-wzcas4zd	91	47	a	a	DT
cord-312119-wzcas4zd	91	48	CO	CO	NNP
cord-312119-wzcas4zd	91	49	2	2	CD
cord-312119-wzcas4zd	91	50	incubator	incubator	NN
cord-312119-wzcas4zd	91	51	.	.	.
cord-312119-wzcas4zd	92	1	After	after	IN
cord-312119-wzcas4zd	92	2	washes	wash	NNS
cord-312119-wzcas4zd	92	3	with	with	IN
cord-312119-wzcas4zd	92	4	PBS	PBS	NNP
cord-312119-wzcas4zd	92	5	to	to	TO
cord-312119-wzcas4zd	92	6	remove	remove	VB
cord-312119-wzcas4zd	92	7	non	non	JJ
cord-312119-wzcas4zd	92	8	-	-	JJ
cord-312119-wzcas4zd	92	9	adherent	adherent	JJ
cord-312119-wzcas4zd	92	10	bacteria	bacteria	NNS
cord-312119-wzcas4zd	92	11	,	,	,
cord-312119-wzcas4zd	92	12	cells	cell	NNS
cord-312119-wzcas4zd	92	13	were	be	VBD
cord-312119-wzcas4zd	92	14	dislodged	dislodge	VBN
cord-312119-wzcas4zd	92	15	,	,	,
cord-312119-wzcas4zd	92	16	lysed	lyse	VBN
cord-312119-wzcas4zd	92	17	,	,	,
cord-312119-wzcas4zd	92	18	then	then	RB
cord-312119-wzcas4zd	92	19	diluted	dilute	VBN
cord-312119-wzcas4zd	92	20	,	,	,
cord-312119-wzcas4zd	92	21	and	and	CC
cord-312119-wzcas4zd	92	22	plated	plate	VBN
cord-312119-wzcas4zd	92	23	on	on	IN
cord-312119-wzcas4zd	92	24	agar	agar	JJ
cord-312119-wzcas4zd	92	25	plates	plate	NNS
cord-312119-wzcas4zd	92	26	for	for	IN
cord-312119-wzcas4zd	92	27	8516	8516	CD
cord-312119-wzcas4zd	92	28	bacteria	bacteria	NNS
cord-312119-wzcas4zd	92	29	counting	count	VBG
cord-312119-wzcas4zd	92	30	(	(	-LRB-
cord-312119-wzcas4zd	92	31	CFUs	CFUs	NNP
cord-312119-wzcas4zd	92	32	)	)	-RRB-
cord-312119-wzcas4zd	92	33	after	after	IN
cord-312119-wzcas4zd	92	34	overnight	overnight	JJ
cord-312119-wzcas4zd	92	35	growth	growth	NN
cord-312119-wzcas4zd	92	36	at	at	IN
cord-312119-wzcas4zd	92	37	37⁰C.	37⁰c.	NN
cord-312119-wzcas4zd	92	38	Neutralizing	neutralize	VBG
cord-312119-wzcas4zd	92	39	epitopes	epitope	NNS
cord-312119-wzcas4zd	92	40	were	be	VBD
cord-312119-wzcas4zd	92	41	identified	identify	VBN
cord-312119-wzcas4zd	92	42	if	if	IN
cord-312119-wzcas4zd	92	43	mouse	mouse	NN
cord-312119-wzcas4zd	92	44	serum	serum	NN
cord-312119-wzcas4zd	92	45	samples	sample	NNS
cord-312119-wzcas4zd	92	46	derived	derive	VBN
cord-312119-wzcas4zd	92	47	from	from	IN
cord-312119-wzcas4zd	92	48	the	the	DT
cord-312119-wzcas4zd	92	49	fusion	fusion	NN
cord-312119-wzcas4zd	92	50	protein	protein	NN
cord-312119-wzcas4zd	92	51	showed	show	VBD
cord-312119-wzcas4zd	92	52	significant	significant	JJ
cord-312119-wzcas4zd	92	53	inhibition	inhibition	NN
cord-312119-wzcas4zd	92	54	against	against	IN
cord-312119-wzcas4zd	92	55	adherence	adherence	NN
cord-312119-wzcas4zd	92	56	from	from	IN
cord-312119-wzcas4zd	92	57	F18-fimbrial	F18-fimbrial	NNP
cord-312119-wzcas4zd	92	58	E.	E.	NNP
cord-312119-wzcas4zd	92	59	coli	coli	NNS
cord-312119-wzcas4zd	92	60	bacteria	bacteria	NNS
cord-312119-wzcas4zd	92	61	,	,	,
cord-312119-wzcas4zd	92	62	compared	compare	VBN
cord-312119-wzcas4zd	92	63	to	to	IN
cord-312119-wzcas4zd	92	64	the	the	DT
cord-312119-wzcas4zd	92	65	control	control	NN
cord-312119-wzcas4zd	92	66	mouse	mouse	NN
cord-312119-wzcas4zd	92	67	serum	serum	NN
cord-312119-wzcas4zd	92	68	samples	sample	NNS
cord-312119-wzcas4zd	92	69	.	.	.
cord-312119-wzcas4zd	93	1	Data	datum	NNS
cord-312119-wzcas4zd	93	2	were	be	VBD
cord-312119-wzcas4zd	93	3	analyzed	analyze	VBN
cord-312119-wzcas4zd	93	4	statistically	statistically	RB
cord-312119-wzcas4zd	93	5	using	use	VBG
cord-312119-wzcas4zd	93	6	GraphPad	GraphPad	NNP
cord-312119-wzcas4zd	93	7	prism	prism	NN
cord-312119-wzcas4zd	93	8	software	software	NN
cord-312119-wzcas4zd	93	9	version	version	NN
cord-312119-wzcas4zd	93	10	7.0	7.0	CD
cord-312119-wzcas4zd	93	11	(	(	-LRB-
cord-312119-wzcas4zd	93	12	La	La	NNP
cord-312119-wzcas4zd	93	13	Jolla	Jolla	NNP
cord-312119-wzcas4zd	93	14	,	,	,
cord-312119-wzcas4zd	93	15	CA	CA	NNP
cord-312119-wzcas4zd	93	16	)	)	-RRB-
cord-312119-wzcas4zd	93	17	.	.	.
cord-312119-wzcas4zd	94	1	ANOVA	ANOVA	NNP
cord-312119-wzcas4zd	94	2	(	(	-LRB-
cord-312119-wzcas4zd	94	3	Two	two	CD
cord-312119-wzcas4zd	94	4	-	-	HYPH
cord-312119-wzcas4zd	94	5	way	way	NN
cord-312119-wzcas4zd	94	6	)	)	-RRB-
cord-312119-wzcas4zd	94	7	was	be	VBD
cord-312119-wzcas4zd	94	8	used	use	VBN
cord-312119-wzcas4zd	94	9	to	to	TO
cord-312119-wzcas4zd	94	10	compare	compare	VB
cord-312119-wzcas4zd	94	11	data	datum	NNS
cord-312119-wzcas4zd	94	12	of	of	IN
cord-312119-wzcas4zd	94	13	competitive	competitive	JJ
cord-312119-wzcas4zd	94	14	ELISA	ELISA	NNP
cord-312119-wzcas4zd	94	15	of	of	IN
cord-312119-wzcas4zd	94	16	screening	screen	VBG
cord-312119-wzcas4zd	94	17	each	each	DT
cord-312119-wzcas4zd	94	18	CfaB	cfab	NN
cord-312119-wzcas4zd	94	19	-	-	HYPH
cord-312119-wzcas4zd	94	20	epitope	epitope	NN
cord-312119-wzcas4zd	94	21	fusion	fusion	NN
cord-312119-wzcas4zd	94	22	protein	protein	NN
cord-312119-wzcas4zd	94	23	competing	compete	VBG
cord-312119-wzcas4zd	94	24	against	against	IN
cord-312119-wzcas4zd	94	25	F18	F18	NNP
cord-312119-wzcas4zd	94	26	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	94	27	for	for	IN
cord-312119-wzcas4zd	94	28	reactivity	reactivity	NN
cord-312119-wzcas4zd	94	29	with	with	IN
cord-312119-wzcas4zd	94	30	anti	anti	JJ
cord-312119-wzcas4zd	94	31	-	-	JJ
cord-312119-wzcas4zd	94	32	F18	f18	JJ
cord-312119-wzcas4zd	94	33	antiserum	antiserum	NN
cord-312119-wzcas4zd	94	34	,	,	,
cord-312119-wzcas4zd	94	35	whereas	whereas	IN
cord-312119-wzcas4zd	94	36	ANOVA	ANOVA	NNP
cord-312119-wzcas4zd	94	37	(	(	-LRB-
cord-312119-wzcas4zd	94	38	One	one	CD
cord-312119-wzcas4zd	94	39	-	-	HYPH
cord-312119-wzcas4zd	94	40	way	way	NN
cord-312119-wzcas4zd	94	41	)	)	-RRB-
cord-312119-wzcas4zd	94	42	was	be	VBD
cord-312119-wzcas4zd	94	43	performed	perform	VBN
cord-312119-wzcas4zd	94	44	to	to	TO
cord-312119-wzcas4zd	94	45	analyze	analyze	VB
cord-312119-wzcas4zd	94	46	Cfab	Cfab	NNP
cord-312119-wzcas4zd	94	47	-	-	HYPH
cord-312119-wzcas4zd	94	48	epitope	epitope	NN
cord-312119-wzcas4zd	94	49	fusions	fusion	NNS
cord-312119-wzcas4zd	94	50	in	in	IN
cord-312119-wzcas4zd	94	51	competitive	competitive	JJ
cord-312119-wzcas4zd	94	52	bacteria	bacteria	NNS
cord-312119-wzcas4zd	94	53	adherence	adherence	NN
cord-312119-wzcas4zd	94	54	inhibition	inhibition	NN
cord-312119-wzcas4zd	94	55	assay	assay	NN
cord-312119-wzcas4zd	94	56	,	,	,
cord-312119-wzcas4zd	94	57	mouse	mouse	NN
cord-312119-wzcas4zd	94	58	serum	serum	NN
cord-312119-wzcas4zd	94	59	anti	anti	JJ
cord-312119-wzcas4zd	94	60	-	-	JJ
cord-312119-wzcas4zd	94	61	F18	f18	JJ
cord-312119-wzcas4zd	94	62	IgG	igg	NN
cord-312119-wzcas4zd	94	63	antibody	antibody	NN
cord-312119-wzcas4zd	94	64	titration	titration	NN
cord-312119-wzcas4zd	94	65	and	and	CC
cord-312119-wzcas4zd	94	66	antibody	antibody	NN
cord-312119-wzcas4zd	94	67	adherence	adherence	NN
cord-312119-wzcas4zd	94	68	inhibition	inhibition	NN
cord-312119-wzcas4zd	94	69	assay	assay	NN
cord-312119-wzcas4zd	94	70	data	datum	NNS
cord-312119-wzcas4zd	94	71	.	.	.
cord-312119-wzcas4zd	95	1	The	the	DT
cord-312119-wzcas4zd	95	2	mean	mean	JJ
cord-312119-wzcas4zd	95	3	±	±	NNP
cord-312119-wzcas4zd	95	4	standard	standard	JJ
cord-312119-wzcas4zd	95	5	deviation	deviation	NN
cord-312119-wzcas4zd	95	6	(	(	-LRB-
cord-312119-wzcas4zd	95	7	SD	sd	NN
cord-312119-wzcas4zd	95	8	)	)	-RRB-
cord-312119-wzcas4zd	95	9	was	be	VBD
cord-312119-wzcas4zd	95	10	used	use	VBN
cord-312119-wzcas4zd	95	11	to	to	TO
cord-312119-wzcas4zd	95	12	express	express	VB
cord-312119-wzcas4zd	95	13	the	the	DT
cord-312119-wzcas4zd	95	14	results	result	NNS
cord-312119-wzcas4zd	95	15	;	;	:
cord-312119-wzcas4zd	95	16	a	a	DT
cord-312119-wzcas4zd	95	17	p	p	NN
cord-312119-wzcas4zd	95	18	value	value	NN
cord-312119-wzcas4zd	95	19	of	of	IN
cord-312119-wzcas4zd	95	20	<	<	NNP
cord-312119-wzcas4zd	95	21	0.05	0.05	CD
cord-312119-wzcas4zd	95	22	indicated	indicate	VBD
cord-312119-wzcas4zd	95	23	differences	difference	NNS
cord-312119-wzcas4zd	95	24	significant	significant	JJ
cord-312119-wzcas4zd	95	25	.	.	.
cord-312119-wzcas4zd	96	1	A	a	DT
cord-312119-wzcas4zd	96	2	total	total	NN
cord-312119-wzcas4zd	96	3	of	of	IN
cord-312119-wzcas4zd	96	4	seven	seven	CD
cord-312119-wzcas4zd	96	5	immunodominant	immunodominant	JJ
cord-312119-wzcas4zd	96	6	epitopes	epitope	NNS
cord-312119-wzcas4zd	96	7	were	be	VBD
cord-312119-wzcas4zd	96	8	in	in	IN
cord-312119-wzcas4zd	96	9	silico	silico	NNS
cord-312119-wzcas4zd	96	10	identified	identify	VBN
cord-312119-wzcas4zd	96	11	,	,	,
cord-312119-wzcas4zd	96	12	at	at	IN
cord-312119-wzcas4zd	96	13	the	the	DT
cord-312119-wzcas4zd	96	14	length	length	NN
cord-312119-wzcas4zd	96	15	ranged	range	VBD
cord-312119-wzcas4zd	96	16	from	from	IN
cord-312119-wzcas4zd	96	17	10	10	CD
cord-312119-wzcas4zd	96	18	to	to	TO
cord-312119-wzcas4zd	96	19	14	14	CD
cord-312119-wzcas4zd	96	20	amino	amino	JJ
cord-312119-wzcas4zd	96	21	acids	acid	NNS
cord-312119-wzcas4zd	96	22	(	(	-LRB-
cord-312119-wzcas4zd	96	23	Table	Table	NNP
cord-312119-wzcas4zd	96	24	3	3	CD
cord-312119-wzcas4zd	96	25	)	)	-RRB-
cord-312119-wzcas4zd	96	26	.	.	.
cord-312119-wzcas4zd	97	1	All	all	DT
cord-312119-wzcas4zd	97	2	seven	seven	CD
cord-312119-wzcas4zd	97	3	epitopes	epitope	NNS
cord-312119-wzcas4zd	97	4	are	be	VBP
cord-312119-wzcas4zd	97	5	discontinuous	discontinuous	JJ
cord-312119-wzcas4zd	97	6	,	,	,
cord-312119-wzcas4zd	97	7	surface	surface	NN
cord-312119-wzcas4zd	97	8	-	-	HYPH
cord-312119-wzcas4zd	97	9	exposed	expose	VBN
cord-312119-wzcas4zd	97	10	,	,	,
cord-312119-wzcas4zd	97	11	and	and	CC
cord-312119-wzcas4zd	97	12	located	locate	VBN
cord-312119-wzcas4zd	97	13	on	on	IN
cord-312119-wzcas4zd	97	14	ẞ	ß	NN
cord-312119-wzcas4zd	97	15	sheets	sheet	NNS
cord-312119-wzcas4zd	97	16	or	or	CC
cord-312119-wzcas4zd	97	17	α	α	NN
cord-312119-wzcas4zd	97	18	-	-	HYPH
cord-312119-wzcas4zd	97	19	helix	helix	NN
cord-312119-wzcas4zd	97	20	extension	extension	NN
cord-312119-wzcas4zd	98	1	(	(	-LRB-
cord-312119-wzcas4zd	98	2	Fig	Fig	NNP
cord-312119-wzcas4zd	98	3	.	.	NNP
cord-312119-wzcas4zd	98	4	1	1	CD
cord-312119-wzcas4zd	98	5	)	)	-RRB-
cord-312119-wzcas4zd	98	6	.	.	.
cord-312119-wzcas4zd	99	1	Seven	seven	CD
cord-312119-wzcas4zd	99	2	CfaB	cfab	NN
cord-312119-wzcas4zd	99	3	-	-	HYPH
cord-312119-wzcas4zd	99	4	epitope	epitope	NN
cord-312119-wzcas4zd	99	5	fusions	fusion	NNS
cord-312119-wzcas4zd	99	6	were	be	VBD
cord-312119-wzcas4zd	99	7	constructed	construct	VBN
cord-312119-wzcas4zd	99	8	,	,	,
cord-312119-wzcas4zd	99	9	designed	design	VBN
cord-312119-wzcas4zd	99	10	as	as	IN
cord-312119-wzcas4zd	99	11	CfaB	CfaB	NNP
cord-312119-wzcas4zd	99	12	-	-	HYPH
cord-312119-wzcas4zd	99	13	FedF	FedF	NNP
cord-312119-wzcas4zd	99	14	-	-	HYPH
cord-312119-wzcas4zd	99	15	ep1	ep1	NN
cord-312119-wzcas4zd	99	16	,	,	,
cord-312119-wzcas4zd	99	17	CfaB	CfaB	NNP
cord-312119-wzcas4zd	99	18	-	-	HYPH
cord-312119-wzcas4zd	99	19	FedF	FedF	NNP
cord-312119-wzcas4zd	99	20	-	-	HYPH
cord-312119-wzcas4zd	99	21	ep2	ep2	NNP
cord-312119-wzcas4zd	99	22	,	,	,
cord-312119-wzcas4zd	99	23	CfaB	CfaB	NNP
cord-312119-wzcas4zd	99	24	-	-	HYPH
cord-312119-wzcas4zd	99	25	FedF	FedF	NNP
cord-312119-wzcas4zd	99	26	-	-	HYPH
cord-312119-wzcas4zd	99	27	ep3	ep3	NNP
cord-312119-wzcas4zd	99	28	,	,	,
cord-312119-wzcas4zd	99	29	CfaB	CfaB	NNP
cord-312119-wzcas4zd	99	30	-	-	HYPH
cord-312119-wzcas4zd	99	31	FedF	FedF	NNP
cord-312119-wzcas4zd	99	32	-	-	HYPH
cord-312119-wzcas4zd	99	33	ep4	ep4	NNP
cord-312119-wzcas4zd	99	34	,	,	,
cord-312119-wzcas4zd	99	35	CfaB	CfaB	NNP
cord-312119-wzcas4zd	99	36	-	-	HYPH
cord-312119-wzcas4zd	99	37	FedF-	FedF-	NNS
cord-312119-wzcas4zd	99	38	T.	t.	NN
cord-312119-wzcas4zd	99	39	Lu	Lu	NNP
cord-312119-wzcas4zd	99	40	et	et	FW
cord-312119-wzcas4zd	99	41	al	al	NNP
cord-312119-wzcas4zd	99	42	.	.	.
cord-312119-wzcas4zd	100	1	Veterinary	Veterinary	NNP
cord-312119-wzcas4zd	100	2	Microbiology	Microbiology	NNP
cord-312119-wzcas4zd	100	3	230	230	CD
cord-312119-wzcas4zd	100	4	(	(	-LRB-
cord-312119-wzcas4zd	100	5	2019	2019	CD
cord-312119-wzcas4zd	100	6	)	)	-RRB-
cord-312119-wzcas4zd	101	1	171	171	CD
cord-312119-wzcas4zd	101	2	-	-	SYM
cord-312119-wzcas4zd	101	3	177	177	CD
cord-312119-wzcas4zd	101	4	ep5	ep5	NNP
cord-312119-wzcas4zd	101	5	,	,	,
cord-312119-wzcas4zd	101	6	CfaB	CfaB	NNP
cord-312119-wzcas4zd	101	7	-	-	HYPH
cord-312119-wzcas4zd	101	8	FedF	FedF	NNP
cord-312119-wzcas4zd	101	9	-	-	HYPH
cord-312119-wzcas4zd	101	10	ep6	ep6	NNP
cord-312119-wzcas4zd	101	11	,	,	,
cord-312119-wzcas4zd	101	12	and	and	CC
cord-312119-wzcas4zd	101	13	CfaB	CfaB	NNP
cord-312119-wzcas4zd	101	14	-	-	HYPH
cord-312119-wzcas4zd	101	15	FedF	FedF	NNP
cord-312119-wzcas4zd	101	16	-	-	HYPH
cord-312119-wzcas4zd	101	17	ep7	ep7	NNP
cord-312119-wzcas4zd	101	18	(	(	-LRB-
cord-312119-wzcas4zd	101	19	Fig	Fig	NNP
cord-312119-wzcas4zd	101	20	.	.	.
cord-312119-wzcas4zd	101	21	S1	S1	NNP
cord-312119-wzcas4zd	101	22	)	)	-RRB-
cord-312119-wzcas4zd	101	23	.	.	.
cord-312119-wzcas4zd	102	1	Epitope	epitope	NN
cord-312119-wzcas4zd	102	2	fusion	fusion	NN
cord-312119-wzcas4zd	102	3	protein	protein	NN
cord-312119-wzcas4zd	102	4	were	be	VBD
cord-312119-wzcas4zd	102	5	extracted	extract	VBN
cord-312119-wzcas4zd	102	6	and	and	CC
cord-312119-wzcas4zd	102	7	refolded	refolde	VBN
cord-312119-wzcas4zd	102	8	(	(	-LRB-
cord-312119-wzcas4zd	102	9	Fig	Fig	NNP
cord-312119-wzcas4zd	102	10	.	.	.
cord-312119-wzcas4zd	102	11	2A	2a	CD
cord-312119-wzcas4zd	102	12	)	)	-RRB-
cord-312119-wzcas4zd	102	13	,	,	,
cord-312119-wzcas4zd	102	14	and	and	CC
cord-312119-wzcas4zd	102	15	recognized	recognize	VBN
cord-312119-wzcas4zd	102	16	by	by	IN
cord-312119-wzcas4zd	102	17	anti	anti	JJ
cord-312119-wzcas4zd	102	18	-	-	JJ
cord-312119-wzcas4zd	102	19	F18	f18	JJ
cord-312119-wzcas4zd	102	20	mouse	mouse	NN
cord-312119-wzcas4zd	102	21	antiserum	antiserum	NN
cord-312119-wzcas4zd	102	22	(	(	-LRB-
cord-312119-wzcas4zd	102	23	Fig	Fig	NNP
cord-312119-wzcas4zd	102	24	.	.	.
cord-312119-wzcas4zd	102	25	2B	2b	CD
cord-312119-wzcas4zd	102	26	)	)	-RRB-
cord-312119-wzcas4zd	102	27	.	.	.
cord-312119-wzcas4zd	103	1	Additionally	additionally	RB
cord-312119-wzcas4zd	103	2	,	,	,
cord-312119-wzcas4zd	103	3	when	when	WRB
cord-312119-wzcas4zd	103	4	coated	coat	VBN
cord-312119-wzcas4zd	103	5	on	on	IN
cord-312119-wzcas4zd	103	6	ELISA	ELISA	NNP
cord-312119-wzcas4zd	103	7	plates	plate	NNS
cord-312119-wzcas4zd	103	8	,	,	,
cord-312119-wzcas4zd	103	9	each	each	DT
cord-312119-wzcas4zd	103	10	of	of	IN
cord-312119-wzcas4zd	103	11	these	these	DT
cord-312119-wzcas4zd	103	12	seven	seven	CD
cord-312119-wzcas4zd	103	13	fusion	fusion	NN
cord-312119-wzcas4zd	103	14	proteins	protein	NNS
cord-312119-wzcas4zd	103	15	reacted	react	VBD
cord-312119-wzcas4zd	103	16	with	with	IN
cord-312119-wzcas4zd	103	17	anti	anti	JJ
cord-312119-wzcas4zd	103	18	-	-	JJ
cord-312119-wzcas4zd	103	19	F18	f18	JJ
cord-312119-wzcas4zd	103	20	antiserum	antiserum	NN
cord-312119-wzcas4zd	103	21	(	(	-LRB-
cord-312119-wzcas4zd	103	22	Fig	Fig	NNP
cord-312119-wzcas4zd	103	23	.	.	.
cord-312119-wzcas4zd	103	24	2C	2C	NNP
cord-312119-wzcas4zd	103	25	)	)	-RRB-
cord-312119-wzcas4zd	103	26	.	.	.
cord-312119-wzcas4zd	104	1	Additionally	additionally	RB
cord-312119-wzcas4zd	104	2	,	,	,
cord-312119-wzcas4zd	104	3	competitive	competitive	JJ
cord-312119-wzcas4zd	104	4	ELISAs	elisa	NNS
cord-312119-wzcas4zd	104	5	using	use	VBG
cord-312119-wzcas4zd	104	6	F18	F18	NNP
cord-312119-wzcas4zd	104	7	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	104	8	as	as	IN
cord-312119-wzcas4zd	104	9	the	the	DT
cord-312119-wzcas4zd	104	10	coating	coating	NN
cord-312119-wzcas4zd	104	11	antigen	antigen	NN
cord-312119-wzcas4zd	104	12	showed	show	VBD
cord-312119-wzcas4zd	104	13	that	that	IN
cord-312119-wzcas4zd	104	14	CfaB	cfab	NN
cord-312119-wzcas4zd	104	15	-	-	HYPH
cord-312119-wzcas4zd	104	16	epitope	epitope	NN
cord-312119-wzcas4zd	104	17	fusion	fusion	NN
cord-312119-wzcas4zd	104	18	proteins	protein	NNS
cord-312119-wzcas4zd	104	19	competed	compete	VBD
cord-312119-wzcas4zd	104	20	with	with	IN
cord-312119-wzcas4zd	104	21	coated	coated	JJ
cord-312119-wzcas4zd	104	22	F18	F18	NNP
cord-312119-wzcas4zd	104	23	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	104	24	for	for	IN
cord-312119-wzcas4zd	104	25	binding	bind	VBG
cord-312119-wzcas4zd	104	26	to	to	IN
cord-312119-wzcas4zd	104	27	anti	anti	JJ
cord-312119-wzcas4zd	104	28	-	-	JJ
cord-312119-wzcas4zd	104	29	F18	f18	JJ
cord-312119-wzcas4zd	104	30	antiserum	antiserum	NN
cord-312119-wzcas4zd	104	31	(	(	-LRB-
cord-312119-wzcas4zd	104	32	Fig	Fig	NNP
cord-312119-wzcas4zd	104	33	.	.	.
cord-312119-wzcas4zd	104	34	3A	3A	NNP
cord-312119-wzcas4zd	104	35	)	)	-RRB-
cord-312119-wzcas4zd	104	36	.	.	.
cord-312119-wzcas4zd	105	1	OD	OD	NNP
cord-312119-wzcas4zd	105	2	readings	reading	NNS
cord-312119-wzcas4zd	105	3	were	be	VBD
cord-312119-wzcas4zd	105	4	significantly	significantly	RB
cord-312119-wzcas4zd	105	5	lower	low	JJR
cord-312119-wzcas4zd	105	6	in	in	IN
cord-312119-wzcas4zd	105	7	wells	well	NNS
cord-312119-wzcas4zd	105	8	with	with	IN
cord-312119-wzcas4zd	105	9	the	the	DT
cord-312119-wzcas4zd	105	10	addition	addition	NN
cord-312119-wzcas4zd	105	11	of	of	IN
cord-312119-wzcas4zd	105	12	individual	individual	JJ
cord-312119-wzcas4zd	105	13	CfaBepitope	CfaBepitope	NNP
cord-312119-wzcas4zd	105	14	fusion	fusion	NN
cord-312119-wzcas4zd	105	15	proteins	protein	NNS
cord-312119-wzcas4zd	105	16	or	or	CC
cord-312119-wzcas4zd	105	17	F18	F18	NNP
cord-312119-wzcas4zd	105	18	fimbria	fimbria	NN
cord-312119-wzcas4zd	105	19	(	(	-LRB-
cord-312119-wzcas4zd	105	20	p	p	NN
cord-312119-wzcas4zd	105	21	<	<	XX
cord-312119-wzcas4zd	105	22	0.01	0.01	CD
cord-312119-wzcas4zd	105	23	;	;	:
cord-312119-wzcas4zd	105	24	as	as	IN
cord-312119-wzcas4zd	105	25	the	the	DT
cord-312119-wzcas4zd	105	26	positive	positive	JJ
cord-312119-wzcas4zd	105	27	control	control	NN
cord-312119-wzcas4zd	105	28	)	)	-RRB-
cord-312119-wzcas4zd	105	29	,	,	,
cord-312119-wzcas4zd	105	30	confirming	confirm	VBG
cord-312119-wzcas4zd	105	31	FedF	FedF	NNP
cord-312119-wzcas4zd	105	32	epitopes	epitope	NNS
cord-312119-wzcas4zd	105	33	presented	present	VBN
cord-312119-wzcas4zd	105	34	in	in	IN
cord-312119-wzcas4zd	105	35	the	the	DT
cord-312119-wzcas4zd	105	36	fusion	fusion	NN
cord-312119-wzcas4zd	105	37	proteins	protein	NNS
cord-312119-wzcas4zd	105	38	retained	retain	VBD
cord-312119-wzcas4zd	105	39	native	native	JJ
cord-312119-wzcas4zd	105	40	antigenic	antigenic	JJ
cord-312119-wzcas4zd	105	41	conformation	conformation	NN
cord-312119-wzcas4zd	105	42	.	.	.
cord-312119-wzcas4zd	106	1	More	more	RBR
cord-312119-wzcas4zd	106	2	importantly	importantly	RB
cord-312119-wzcas4zd	106	3	,	,	,
cord-312119-wzcas4zd	106	4	CfaB	cfab	NN
cord-312119-wzcas4zd	106	5	-	-	HYPH
cord-312119-wzcas4zd	106	6	epitope	epitope	NN
cord-312119-wzcas4zd	106	7	fusion	fusion	NN
cord-312119-wzcas4zd	106	8	proteins	protein	NNS
cord-312119-wzcas4zd	106	9	bound	bind	VBN
cord-312119-wzcas4zd	106	10	to	to	IN
cord-312119-wzcas4zd	106	11	anti	anti	JJ
cord-312119-wzcas4zd	106	12	-	-	JJ
cord-312119-wzcas4zd	106	13	F18	f18	JJ
cord-312119-wzcas4zd	106	14	antiserum	antiserum	NN
cord-312119-wzcas4zd	106	15	and	and	CC
cord-312119-wzcas4zd	106	16	reduced	reduce	VBN
cord-312119-wzcas4zd	106	17	anti	anti	JJ
cord-312119-wzcas4zd	106	18	-	-	JJ
cord-312119-wzcas4zd	106	19	F18	f18	JJ
cord-312119-wzcas4zd	106	20	antibodies	antibody	NNS
cord-312119-wzcas4zd	106	21	from	from	IN
cord-312119-wzcas4zd	106	22	inhibiting	inhibit	VBG
cord-312119-wzcas4zd	106	23	the	the	DT
cord-312119-wzcas4zd	106	24	adherence	adherence	NN
cord-312119-wzcas4zd	106	25	F18-fimbrial	F18-fimbrial	NNP
cord-312119-wzcas4zd	106	26	E.	E.	NNP
cord-312119-wzcas4zd	106	27	coli	coli	NNS
cord-312119-wzcas4zd	106	28	bacteria	bacteria	NNS
cord-312119-wzcas4zd	106	29	to	to	IN
cord-312119-wzcas4zd	106	30	pig	pig	NN
cord-312119-wzcas4zd	106	31	cell	cell	NN
cord-312119-wzcas4zd	106	32	line	line	NN
cord-312119-wzcas4zd	106	33	IPEC	IPEC	NNP
cord-312119-wzcas4zd	106	34	-	-	HYPH
cord-312119-wzcas4zd	106	35	J2	J2	NNP
cord-312119-wzcas4zd	106	36	(	(	-LRB-
cord-312119-wzcas4zd	106	37	Fig	Fig	NNP
cord-312119-wzcas4zd	106	38	.	.	.
cord-312119-wzcas4zd	106	39	3B	3B	NNP
cord-312119-wzcas4zd	106	40	)	)	-RRB-
cord-312119-wzcas4zd	106	41	.	.	.
cord-312119-wzcas4zd	107	1	The	the	DT
cord-312119-wzcas4zd	107	2	addition	addition	NN
cord-312119-wzcas4zd	107	3	of	of	IN
cord-312119-wzcas4zd	107	4	CfaB	CfaB	NNP
cord-312119-wzcas4zd	107	5	-	-	HYPH
cord-312119-wzcas4zd	107	6	FedF	FedF	NNP
cord-312119-wzcas4zd	107	7	-	-	HYPH
cord-312119-wzcas4zd	107	8	ep1	ep1	NN
cord-312119-wzcas4zd	107	9	or	or	CC
cord-312119-wzcas4zd	107	10	CfaB	CfaB	NNP
cord-312119-wzcas4zd	107	11	-	-	HYPH
cord-312119-wzcas4zd	107	12	FedF	FedF	NNP
cord-312119-wzcas4zd	107	13	-	-	HYPH
cord-312119-wzcas4zd	107	14	ep3	ep3	NNP
cord-312119-wzcas4zd	107	15	fusion	fusion	NN
cord-312119-wzcas4zd	107	16	significantly	significantly	RB
cord-312119-wzcas4zd	107	17	reduced	reduce	VBN
cord-312119-wzcas4zd	107	18	anti	anti	JJ
cord-312119-wzcas4zd	107	19	-	-	JJ
cord-312119-wzcas4zd	107	20	F18	f18	JJ
cord-312119-wzcas4zd	107	21	antiserum	antiserum	NN
cord-312119-wzcas4zd	107	22	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	107	23	activity	activity	NN
cord-312119-wzcas4zd	107	24	for	for	IN
cord-312119-wzcas4zd	107	25	blocking	block	VBG
cord-312119-wzcas4zd	107	26	the	the	DT
cord-312119-wzcas4zd	107	27	adherence	adherence	NN
cord-312119-wzcas4zd	107	28	of	of	IN
cord-312119-wzcas4zd	107	29	8516	8516	CD
cord-312119-wzcas4zd	107	30	bacteria	bacteria	NNS
cord-312119-wzcas4zd	107	31	to	to	IN
cord-312119-wzcas4zd	107	32	IPEC	IPEC	NNP
cord-312119-wzcas4zd	107	33	-	-	HYPH
cord-312119-wzcas4zd	107	34	J2	j2	NN
cord-312119-wzcas4zd	107	35	cells	cell	NNS
cord-312119-wzcas4zd	107	36	(	(	-LRB-
cord-312119-wzcas4zd	107	37	p	p	NN
cord-312119-wzcas4zd	107	38	<	<	XX
cord-312119-wzcas4zd	107	39	0.05	0.05	CD
cord-312119-wzcas4zd	107	40	)	)	-RRB-
cord-312119-wzcas4zd	107	41	when	when	WRB
cord-312119-wzcas4zd	107	42	compared	compare	VBN
cord-312119-wzcas4zd	107	43	to	to	IN
cord-312119-wzcas4zd	107	44	other	other	JJ
cord-312119-wzcas4zd	107	45	epitope	epitope	NN
cord-312119-wzcas4zd	107	46	fusions	fusion	NNS
cord-312119-wzcas4zd	107	47	,	,	,
cord-312119-wzcas4zd	107	48	shown	show	VBN
cord-312119-wzcas4zd	107	49	more	more	JJR
cord-312119-wzcas4zd	107	50	bacteria	bacteria	NNS
cord-312119-wzcas4zd	107	51	adhered	adhere	VBN
cord-312119-wzcas4zd	107	52	to	to	IN
cord-312119-wzcas4zd	107	53	IPEC	IPEC	NNP
cord-312119-wzcas4zd	107	54	-	-	HYPH
cord-312119-wzcas4zd	107	55	J2	j2	NN
cord-312119-wzcas4zd	107	56	cells	cell	NNS
cord-312119-wzcas4zd	107	57	(	(	-LRB-
cord-312119-wzcas4zd	107	58	Fig	fig	NN
cord-312119-wzcas4zd	107	59	.	.	.
cord-312119-wzcas4zd	107	60	3B	3B	NNP
cord-312119-wzcas4zd	107	61	)	)	-RRB-
cord-312119-wzcas4zd	107	62	.	.	.
cord-312119-wzcas4zd	108	1	Mice	mouse	NNS
cord-312119-wzcas4zd	108	2	immunized	immunize	VBN
cord-312119-wzcas4zd	108	3	with	with	IN
cord-312119-wzcas4zd	108	4	CfaB	cfab	NN
cord-312119-wzcas4zd	108	5	-	-	HYPH
cord-312119-wzcas4zd	108	6	epitope	epitope	NN
cord-312119-wzcas4zd	108	7	fusion	fusion	NN
cord-312119-wzcas4zd	108	8	proteins	protein	NNS
cord-312119-wzcas4zd	108	9	had	have	VBD
cord-312119-wzcas4zd	108	10	anti	anti	JJ
cord-312119-wzcas4zd	108	11	-	-	JJ
cord-312119-wzcas4zd	108	12	F18	f18	JJ
cord-312119-wzcas4zd	108	13	IgG	igg	NN
cord-312119-wzcas4zd	108	14	antibody	antibody	NN
cord-312119-wzcas4zd	108	15	titers	titer	NNS
cord-312119-wzcas4zd	108	16	detected	detect	VBD
cord-312119-wzcas4zd	108	17	in	in	IN
cord-312119-wzcas4zd	108	18	serum	serum	NN
cord-312119-wzcas4zd	108	19	samples	sample	NNS
cord-312119-wzcas4zd	108	20	at	at	IN
cord-312119-wzcas4zd	108	21	3.65	3.65	CD
cord-312119-wzcas4zd	108	22	±	±	CD
cord-312119-wzcas4zd	108	23	0.39	0.39	CD
cord-312119-wzcas4zd	108	24	(	(	-LRB-
cord-312119-wzcas4zd	108	25	CfaB	CfaB	NNP
cord-312119-wzcas4zd	108	26	-	-	HYPH
cord-312119-wzcas4zd	108	27	FedF	FedF	NNP
cord-312119-wzcas4zd	108	28	-	-	HYPH
cord-312119-wzcas4zd	108	29	ep1	ep1	NNP
cord-312119-wzcas4zd	108	30	)	)	-RRB-
cord-312119-wzcas4zd	108	31	,	,	,
cord-312119-wzcas4zd	108	32	2.42	2.42	CD
cord-312119-wzcas4zd	108	33	±	±	CD
cord-312119-wzcas4zd	108	34	0.536	0.536	CD
cord-312119-wzcas4zd	109	1	(	(	-LRB-
cord-312119-wzcas4zd	109	2	CfaB	CfaB	NNP
cord-312119-wzcas4zd	109	3	-	-	HYPH
cord-312119-wzcas4zd	109	4	FedF	FedF	NNP
cord-312119-wzcas4zd	109	5	-	-	HYPH
cord-312119-wzcas4zd	109	6	ep2	ep2	NNP
cord-312119-wzcas4zd	109	7	)	)	-RRB-
cord-312119-wzcas4zd	109	8	,	,	,
cord-312119-wzcas4zd	109	9	3.65	3.65	CD
cord-312119-wzcas4zd	109	10	±	±	CD
cord-312119-wzcas4zd	109	11	0.148	0.148	CD
cord-312119-wzcas4zd	110	1	(	(	-LRB-
cord-312119-wzcas4zd	110	2	CfaB	CfaB	NNP
cord-312119-wzcas4zd	110	3	-	-	HYPH
cord-312119-wzcas4zd	110	4	FedF	FedF	NNP
cord-312119-wzcas4zd	110	5	-	-	HYPH
cord-312119-wzcas4zd	110	6	ep3	ep3	NNP
cord-312119-wzcas4zd	110	7	)	)	-RRB-
cord-312119-wzcas4zd	110	8	,	,	.
cord-312119-wzcas4zd	111	1	3.21	3.21	CD
cord-312119-wzcas4zd	111	2	±	±	CD
cord-312119-wzcas4zd	111	3	0.484	0.484	CD
cord-312119-wzcas4zd	112	1	(	(	-LRB-
cord-312119-wzcas4zd	112	2	CfaB	CfaB	NNP
cord-312119-wzcas4zd	112	3	-	-	HYPH
cord-312119-wzcas4zd	112	4	FedF	FedF	NNP
cord-312119-wzcas4zd	112	5	-	-	HYPH
cord-312119-wzcas4zd	112	6	ep4	ep4	NNP
cord-312119-wzcas4zd	112	7	)	)	-RRB-
cord-312119-wzcas4zd	112	8	,	,	,
cord-312119-wzcas4zd	112	9	3.68	3.68	CD
cord-312119-wzcas4zd	112	10	±	±	CD
cord-312119-wzcas4zd	112	11	0.373	0.373	CD
cord-312119-wzcas4zd	112	12	(	(	-LRB-
cord-312119-wzcas4zd	112	13	CfaB	CfaB	NNP
cord-312119-wzcas4zd	112	14	-	-	HYPH
cord-312119-wzcas4zd	112	15	FedF	FedF	NNP
cord-312119-wzcas4zd	112	16	-	-	HYPH
cord-312119-wzcas4zd	112	17	ep5	ep5	NNP
cord-312119-wzcas4zd	112	18	)	)	-RRB-
cord-312119-wzcas4zd	112	19	,	,	,
cord-312119-wzcas4zd	112	20	3.61	3.61	CD
cord-312119-wzcas4zd	112	21	±	±	CD
cord-312119-wzcas4zd	112	22	0.308	0.308	CD
cord-312119-wzcas4zd	112	23	(	(	-LRB-
cord-312119-wzcas4zd	112	24	CfaB	CfaB	NNP
cord-312119-wzcas4zd	112	25	-	-	HYPH
cord-312119-wzcas4zd	112	26	FedF	FedF	NNP
cord-312119-wzcas4zd	112	27	-	-	HYPH
cord-312119-wzcas4zd	112	28	ep6	ep6	NNP
cord-312119-wzcas4zd	112	29	)	)	-RRB-
cord-312119-wzcas4zd	112	30	,	,	,
cord-312119-wzcas4zd	112	31	and	and	CC
cord-312119-wzcas4zd	112	32	3.45	3.45	CD
cord-312119-wzcas4zd	112	33	±	±	CD
cord-312119-wzcas4zd	112	34	0.471	0.471	CD
cord-312119-wzcas4zd	112	35	(	(	-LRB-
cord-312119-wzcas4zd	112	36	CfaB	CfaB	NNP
cord-312119-wzcas4zd	112	37	-	-	HYPH
cord-312119-wzcas4zd	112	38	FedF	FedF	NNP
cord-312119-wzcas4zd	112	39	-	-	HYPH
cord-312119-wzcas4zd	112	40	ep7	ep7	NNP
cord-312119-wzcas4zd	112	41	)	)	-RRB-
cord-312119-wzcas4zd	113	1	(	(	-LRB-
cord-312119-wzcas4zd	113	2	Fig	Fig	NNP
cord-312119-wzcas4zd	113	3	.	.	.
cord-312119-wzcas4zd	113	4	4A	4a	CD
cord-312119-wzcas4zd	113	5	)	)	-RRB-
cord-312119-wzcas4zd	113	6	.	.	.
cord-312119-wzcas4zd	114	1	No	no	DT
cord-312119-wzcas4zd	114	2	anti	anti	JJ
cord-312119-wzcas4zd	114	3	-	-	JJ
cord-312119-wzcas4zd	114	4	F18	f18	JJ
cord-312119-wzcas4zd	114	5	antibodies	antibody	NNS
cord-312119-wzcas4zd	114	6	detected	detect	VBN
cord-312119-wzcas4zd	114	7	in	in	IN
cord-312119-wzcas4zd	114	8	the	the	DT
cord-312119-wzcas4zd	114	9	serum	serum	NN
cord-312119-wzcas4zd	114	10	of	of	IN
cord-312119-wzcas4zd	114	11	the	the	DT
cord-312119-wzcas4zd	114	12	control	control	NN
cord-312119-wzcas4zd	114	13	mice	mouse	NNS
cord-312119-wzcas4zd	114	14	or	or	CC
cord-312119-wzcas4zd	114	15	from	from	IN
cord-312119-wzcas4zd	114	16	the	the	DT
cord-312119-wzcas4zd	114	17	serum	serum	NN
cord-312119-wzcas4zd	114	18	collected	collect	VBN
cord-312119-wzcas4zd	114	19	prior	prior	RB
cord-312119-wzcas4zd	114	20	to	to	IN
cord-312119-wzcas4zd	114	21	the	the	DT
cord-312119-wzcas4zd	114	22	primary	primary	JJ
cord-312119-wzcas4zd	114	23	immunization	immunization	NN
cord-312119-wzcas4zd	114	24	.	.	.
cord-312119-wzcas4zd	115	1	Anti	anti	JJ
cord-312119-wzcas4zd	115	2	-	-	JJ
cord-312119-wzcas4zd	115	3	F18	f18	JJ
cord-312119-wzcas4zd	115	4	IgG	igg	NN
cord-312119-wzcas4zd	115	5	titers	titer	NNS
cord-312119-wzcas4zd	115	6	in	in	IN
cord-312119-wzcas4zd	115	7	the	the	DT
cord-312119-wzcas4zd	115	8	group	group	NN
cord-312119-wzcas4zd	115	9	immunized	immunize	VBN
cord-312119-wzcas4zd	115	10	with	with	IN
cord-312119-wzcas4zd	115	11	CfaB	CfaB	NNP
cord-312119-wzcas4zd	115	12	-	-	HYPH
cord-312119-wzcas4zd	115	13	FedF	FedF	NNP
cord-312119-wzcas4zd	115	14	-	-	HYPH
cord-312119-wzcas4zd	115	15	ep2	ep2	NNP
cord-312119-wzcas4zd	115	16	were	be	VBD
cord-312119-wzcas4zd	115	17	significantly	significantly	RB
cord-312119-wzcas4zd	115	18	lower	low	JJR
cord-312119-wzcas4zd	115	19	than	than	IN
cord-312119-wzcas4zd	115	20	the	the	DT
cord-312119-wzcas4zd	115	21	titers	titer	NNS
cord-312119-wzcas4zd	115	22	of	of	IN
cord-312119-wzcas4zd	115	23	the	the	DT
cord-312119-wzcas4zd	115	24	groups	group	NNS
cord-312119-wzcas4zd	115	25	immunized	immunize	VBN
cord-312119-wzcas4zd	115	26	with	with	IN
cord-312119-wzcas4zd	115	27	the	the	DT
cord-312119-wzcas4zd	115	28	other	other	JJ
cord-312119-wzcas4zd	115	29	CfaB	cfab	NN
cord-312119-wzcas4zd	115	30	-	-	HYPH
cord-312119-wzcas4zd	115	31	epitope	epitope	NN
cord-312119-wzcas4zd	115	32	fusions	fusion	NNS
cord-312119-wzcas4zd	115	33	(	(	-LRB-
cord-312119-wzcas4zd	115	34	p	p	NN
cord-312119-wzcas4zd	115	35	<	<	XX
cord-312119-wzcas4zd	115	36	0.01	0.01	CD
cord-312119-wzcas4zd	115	37	)	)	-RRB-
cord-312119-wzcas4zd	115	38	.	.	.
cord-312119-wzcas4zd	115	39	 	 	_SP
cord-312119-wzcas4zd	116	1	Serum	serum	NN
cord-312119-wzcas4zd	116	2	samples	sample	NNS
cord-312119-wzcas4zd	116	3	of	of	IN
cord-312119-wzcas4zd	116	4	the	the	DT
cord-312119-wzcas4zd	116	5	mice	mouse	NNS
cord-312119-wzcas4zd	116	6	immunized	immunize	VBN
cord-312119-wzcas4zd	116	7	with	with	IN
cord-312119-wzcas4zd	116	8	CfaB	cfab	NN
cord-312119-wzcas4zd	116	9	-	-	HYPH
cord-312119-wzcas4zd	116	10	epitope	epitope	NN
cord-312119-wzcas4zd	116	11	fusion	fusion	NN
cord-312119-wzcas4zd	116	12	proteins	protein	NNS
cord-312119-wzcas4zd	116	13	exhibited	exhibit	VBD
cord-312119-wzcas4zd	116	14	adherence	adherence	NN
cord-312119-wzcas4zd	116	15	inhibition	inhibition	NN
cord-312119-wzcas4zd	116	16	activities	activity	NNS
cord-312119-wzcas4zd	116	17	against	against	IN
cord-312119-wzcas4zd	116	18	F18-fimbrial	F18-fimbrial	NNP
cord-312119-wzcas4zd	116	19	E.	E.	NNP
cord-312119-wzcas4zd	116	20	coli	coli	NNS
cord-312119-wzcas4zd	116	21	8516	8516	CD
cord-312119-wzcas4zd	117	1	(	(	-LRB-
cord-312119-wzcas4zd	117	2	Fig	Fig	NNP
cord-312119-wzcas4zd	117	3	.	.	.
cord-312119-wzcas4zd	117	4	4B	4b	CD
cord-312119-wzcas4zd	117	5	)	)	-RRB-
cord-312119-wzcas4zd	117	6	.	.	.
cord-312119-wzcas4zd	118	1	Treated	treat	VBN
cord-312119-wzcas4zd	118	2	with	with	IN
cord-312119-wzcas4zd	118	3	the	the	DT
cord-312119-wzcas4zd	118	4	serum	serum	NN
cord-312119-wzcas4zd	118	5	of	of	IN
cord-312119-wzcas4zd	118	6	mice	mouse	NNS
cord-312119-wzcas4zd	118	7	immunized	immunize	VBN
cord-312119-wzcas4zd	118	8	with	with	IN
cord-312119-wzcas4zd	118	9	CfaB	CfaB	NNP
cord-312119-wzcas4zd	118	10	-	-	HYPH
cord-312119-wzcas4zd	118	11	FedF	FedF	NNP
cord-312119-wzcas4zd	118	12	-	-	HYPH
cord-312119-wzcas4zd	118	13	ep3	ep3	NNP
cord-312119-wzcas4zd	118	14	(	(	-LRB-
cord-312119-wzcas4zd	118	15	15	15	CD
cord-312119-wzcas4zd	118	16	±	±	CD
cord-312119-wzcas4zd	118	17	3.5	3.5	CD
cord-312119-wzcas4zd	118	18	,	,	,
cord-312119-wzcas4zd	118	19	%	%	NN
cord-312119-wzcas4zd	118	20	)	)	-RRB-
cord-312119-wzcas4zd	118	21	or	or	CC
cord-312119-wzcas4zd	118	22	CfaB	CfaB	NNP
cord-312119-wzcas4zd	118	23	-	-	HYPH
cord-312119-wzcas4zd	118	24	FedF	FedF	NNP
cord-312119-wzcas4zd	118	25	-	-	HYPH
cord-312119-wzcas4zd	118	26	ep7	ep7	NNP
cord-312119-wzcas4zd	118	27	(	(	-LRB-
cord-312119-wzcas4zd	118	28	16.6	16.6	CD
cord-312119-wzcas4zd	118	29	±	±	NNP
cord-312119-wzcas4zd	118	30	5	5	CD
cord-312119-wzcas4zd	118	31	,	,	,
cord-312119-wzcas4zd	118	32	%	%	NN
cord-312119-wzcas4zd	118	33	)	)	-RRB-
cord-312119-wzcas4zd	118	34	,	,	,
cord-312119-wzcas4zd	118	35	8516	8516	CD
cord-312119-wzcas4zd	118	36	had	have	VBD
cord-312119-wzcas4zd	118	37	the	the	DT
cord-312119-wzcas4zd	118	38	fewest	few	JJS
cord-312119-wzcas4zd	118	39	bacteria	bacteria	NNS
cord-312119-wzcas4zd	118	40	adherent	adherent	JJ
cord-312119-wzcas4zd	118	41	to	to	IN
cord-312119-wzcas4zd	118	42	IPEC	IPEC	NNP
cord-312119-wzcas4zd	118	43	-	-	HYPH
cord-312119-wzcas4zd	118	44	J2	j2	NN
cord-312119-wzcas4zd	118	45	cells	cell	NNS
cord-312119-wzcas4zd	118	46	.	.	.
cord-312119-wzcas4zd	119	1	One	one	CD
cord-312119-wzcas4zd	119	2	-	-	HYPH
cord-312119-wzcas4zd	119	3	way	way	NN
cord-312119-wzcas4zd	119	4	ANOVA	anova	NN
cord-312119-wzcas4zd	119	5	test	test	NN
cord-312119-wzcas4zd	119	6	indicated	indicate	VBD
cord-312119-wzcas4zd	119	7	that	that	IN
cord-312119-wzcas4zd	119	8	serum	serum	NN
cord-312119-wzcas4zd	119	9	antibodies	antibody	NNS
cord-312119-wzcas4zd	119	10	of	of	IN
cord-312119-wzcas4zd	119	11	the	the	DT
cord-312119-wzcas4zd	119	12	mice	mouse	NNS
cord-312119-wzcas4zd	119	13	immunized	immunize	VBN
cord-312119-wzcas4zd	119	14	with	with	IN
cord-312119-wzcas4zd	119	15	CfaB	CfaB	NNP
cord-312119-wzcas4zd	119	16	-	-	HYPH
cord-312119-wzcas4zd	119	17	FedF	FedF	NNP
cord-312119-wzcas4zd	119	18	-	-	HYPH
cord-312119-wzcas4zd	119	19	ep3	ep3	NNP
cord-312119-wzcas4zd	119	20	or	or	CC
cord-312119-wzcas4zd	119	21	CfaB	CfaB	NNP
cord-312119-wzcas4zd	119	22	-	-	HYPH
cord-312119-wzcas4zd	119	23	FedF	FedF	NNP
cord-312119-wzcas4zd	119	24	-	-	HYPH
cord-312119-wzcas4zd	119	25	ep7	ep7	NNP
cord-312119-wzcas4zd	119	26	were	be	VBD
cord-312119-wzcas4zd	119	27	most	most	RBS
cord-312119-wzcas4zd	119	28	effective	effective	JJ
cord-312119-wzcas4zd	119	29	in	in	IN
cord-312119-wzcas4zd	119	30	inhibiting	inhibit	VBG
cord-312119-wzcas4zd	119	31	8516	8516	CD
cord-312119-wzcas4zd	119	32	adherence	adherence	NN
cord-312119-wzcas4zd	119	33	.	.	.
cord-312119-wzcas4zd	120	1	Vaccination	vaccination	NN
cord-312119-wzcas4zd	120	2	with	with	IN
cord-312119-wzcas4zd	120	3	live	live	JJ
cord-312119-wzcas4zd	120	4	and	and	CC
cord-312119-wzcas4zd	120	5	subunit	subunit	NN
cord-312119-wzcas4zd	120	6	vaccines	vaccine	NNS
cord-312119-wzcas4zd	120	7	has	have	VBZ
cord-312119-wzcas4zd	120	8	been	be	VBN
cord-312119-wzcas4zd	120	9	explored	explore	VBN
cord-312119-wzcas4zd	120	10	in	in	IN
cord-312119-wzcas4zd	120	11	the	the	DT
cord-312119-wzcas4zd	120	12	past	past	JJ
cord-312119-wzcas4zd	120	13	decades	decade	NNS
cord-312119-wzcas4zd	120	14	,	,	,
cord-312119-wzcas4zd	120	15	and	and	CC
cord-312119-wzcas4zd	120	16	remains	remain	VBZ
cord-312119-wzcas4zd	120	17	the	the	DT
cord-312119-wzcas4zd	120	18	most	most	RBS
cord-312119-wzcas4zd	120	19	promising	promising	JJ
cord-312119-wzcas4zd	120	20	for	for	IN
cord-312119-wzcas4zd	120	21	PWD	pwd	NN
cord-312119-wzcas4zd	120	22	prevention	prevention	NN
cord-312119-wzcas4zd	121	1	(	(	-LRB-
cord-312119-wzcas4zd	121	2	Fairbrother	Fairbrother	NNP
cord-312119-wzcas4zd	121	3	et	et	NNP
cord-312119-wzcas4zd	121	4	al	al	NNP
cord-312119-wzcas4zd	121	5	.	.	.
cord-312119-wzcas4zd	122	1	,	,	,
cord-312119-wzcas4zd	122	2	2005	2005	CD
cord-312119-wzcas4zd	122	3	;	;	:
cord-312119-wzcas4zd	122	4	Melkebeek	Melkebeek	NNP
cord-312119-wzcas4zd	122	5	et	et	NNP
cord-312119-wzcas4zd	122	6	al	al	NNP
cord-312119-wzcas4zd	122	7	.	.	NNP
cord-312119-wzcas4zd	122	8	,	,	,
cord-312119-wzcas4zd	122	9	2013	2013	CD
cord-312119-wzcas4zd	122	10	)	)	-RRB-
cord-312119-wzcas4zd	122	11	.	.	.
cord-312119-wzcas4zd	123	1	Since	since	IN
cord-312119-wzcas4zd	123	2	ETEC	etec	JJ
cord-312119-wzcas4zd	123	3	strains	strain	NNS
cord-312119-wzcas4zd	123	4	expressing	express	VBG
cord-312119-wzcas4zd	123	5	K88	K88	NNP
cord-312119-wzcas4zd	123	6	or	or	CC
cord-312119-wzcas4zd	123	7	F18	F18	NNP
cord-312119-wzcas4zd	123	8	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	123	9	cause	cause	VB
cord-312119-wzcas4zd	123	10	nearly	nearly	RB
cord-312119-wzcas4zd	123	11	all	all	DT
cord-312119-wzcas4zd	123	12	PWD	pwd	NN
cord-312119-wzcas4zd	123	13	cases	case	NNS
cord-312119-wzcas4zd	123	14	,	,	,
cord-312119-wzcas4zd	123	15	F18	F18	NNP
cord-312119-wzcas4zd	123	16	and	and	CC
cord-312119-wzcas4zd	123	17	K88	K88	NNP
cord-312119-wzcas4zd	123	18	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	123	19	have	have	VBP
cord-312119-wzcas4zd	123	20	been	be	VBN
cord-312119-wzcas4zd	123	21	the	the	DT
cord-312119-wzcas4zd	123	22	main	main	JJ
cord-312119-wzcas4zd	123	23	targets	target	NNS
cord-312119-wzcas4zd	123	24	in	in	IN
cord-312119-wzcas4zd	123	25	vaccine	vaccine	NN
cord-312119-wzcas4zd	123	26	development	development	NN
cord-312119-wzcas4zd	123	27	.	.	.
cord-312119-wzcas4zd	124	1	While	while	IN
cord-312119-wzcas4zd	124	2	oral	oral	JJ
cord-312119-wzcas4zd	124	3	administration	administration	NN
cord-312119-wzcas4zd	124	4	of	of	IN
cord-312119-wzcas4zd	124	5	purified	purify	VBN
cord-312119-wzcas4zd	124	6	K88	K88	NNP
cord-312119-wzcas4zd	124	7	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	124	8	induced	induce	VBN
cord-312119-wzcas4zd	124	9	K88-specific	K88-specific	NNP
cord-312119-wzcas4zd	124	10	antibodies	antibody	NNS
cord-312119-wzcas4zd	124	11	and	and	CC
cord-312119-wzcas4zd	124	12	protected	protect	VBN
cord-312119-wzcas4zd	124	13	pigs	pig	NNS
cord-312119-wzcas4zd	124	14	against	against	IN
cord-312119-wzcas4zd	124	15	a	a	DT
cord-312119-wzcas4zd	124	16	homologous	homologous	JJ
cord-312119-wzcas4zd	124	17	challenge	challenge	NN
cord-312119-wzcas4zd	124	18	(	(	-LRB-
cord-312119-wzcas4zd	124	19	Van	Van	NNP
cord-312119-wzcas4zd	124	20	den	den	NN
cord-312119-wzcas4zd	124	21	Broeck	Broeck	NNP
cord-312119-wzcas4zd	124	22	et	et	NNP
cord-312119-wzcas4zd	124	23	al	al	NNP
cord-312119-wzcas4zd	124	24	.	.	NNP
cord-312119-wzcas4zd	124	25	,	,	,
cord-312119-wzcas4zd	124	26	1999a	1999a	CD
cord-312119-wzcas4zd	124	27	,	,	,
cord-312119-wzcas4zd	124	28	b	b	LS
cord-312119-wzcas4zd	124	29	)	)	-RRB-
cord-312119-wzcas4zd	124	30	,	,	,
cord-312119-wzcas4zd	124	31	administration	administration	NN
cord-312119-wzcas4zd	124	32	of	of	IN
cord-312119-wzcas4zd	124	33	purified	purify	VBN
cord-312119-wzcas4zd	124	34	F18	F18	NNP
cord-312119-wzcas4zd	124	35	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	124	36	did	do	VBD
cord-312119-wzcas4zd	124	37	not	not	RB
cord-312119-wzcas4zd	124	38	induce	induce	VB
cord-312119-wzcas4zd	124	39	protective	protective	JJ
cord-312119-wzcas4zd	124	40	immunity	immunity	NN
cord-312119-wzcas4zd	124	41	against	against	IN
cord-312119-wzcas4zd	124	42	F18	f18	JJ
cord-312119-wzcas4zd	124	43	ETEC	etec	JJ
cord-312119-wzcas4zd	124	44	challenge	challenge	NN
cord-312119-wzcas4zd	124	45	in	in	IN
cord-312119-wzcas4zd	124	46	pigs	pig	NNS
cord-312119-wzcas4zd	124	47	.	.	.
cord-312119-wzcas4zd	125	1	Similarly	similarly	RB
cord-312119-wzcas4zd	125	2	,	,	,
cord-312119-wzcas4zd	125	3	live	live	JJ
cord-312119-wzcas4zd	125	4	vaccine	vaccine	NN
cord-312119-wzcas4zd	125	5	candidates	candidate	NNS
cord-312119-wzcas4zd	125	6	derived	derive	VBN
cord-312119-wzcas4zd	125	7	from	from	IN
cord-312119-wzcas4zd	125	8	avirulent	avirulent	JJ
cord-312119-wzcas4zd	125	9	E.	E.	NNP
cord-312119-wzcas4zd	125	10	coli	coli	NNS
cord-312119-wzcas4zd	125	11	field	field	NN
cord-312119-wzcas4zd	125	12	isolates	isolate	NNS
cord-312119-wzcas4zd	125	13	expressing	express	VBG
cord-312119-wzcas4zd	125	14	K88	K88	NNP
cord-312119-wzcas4zd	125	15	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	125	16	induced	induce	VBN
cord-312119-wzcas4zd	125	17	K88specific	K88specific	NNP
cord-312119-wzcas4zd	125	18	antibodies	antibody	NNS
cord-312119-wzcas4zd	125	19	and	and	CC
cord-312119-wzcas4zd	125	20	protected	protect	VBN
cord-312119-wzcas4zd	125	21	against	against	IN
cord-312119-wzcas4zd	125	22	colonization	colonization	NN
cord-312119-wzcas4zd	125	23	by	by	IN
cord-312119-wzcas4zd	125	24	a	a	DT
cord-312119-wzcas4zd	125	25	K88	K88	NNP
cord-312119-wzcas4zd	125	26	ETEC	etec	JJ
cord-312119-wzcas4zd	125	27	challenge	challenge	NN
cord-312119-wzcas4zd	125	28	strain	strain	NN
cord-312119-wzcas4zd	125	29	(	(	-LRB-
cord-312119-wzcas4zd	125	30	Bianchi	Bianchi	NNP
cord-312119-wzcas4zd	125	31	et	et	NNP
cord-312119-wzcas4zd	125	32	al	al	NNP
cord-312119-wzcas4zd	125	33	.	.	NNP
cord-312119-wzcas4zd	125	34	,	,	,
cord-312119-wzcas4zd	125	35	1996	1996	CD
cord-312119-wzcas4zd	125	36	;	;	:
cord-312119-wzcas4zd	125	37	Francis	Francis	NNP
cord-312119-wzcas4zd	125	38	and	and	CC
cord-312119-wzcas4zd	125	39	Willgohs	Willgohs	NNP
cord-312119-wzcas4zd	125	40	,	,	,
cord-312119-wzcas4zd	125	41	1991	1991	CD
cord-312119-wzcas4zd	125	42	;	;	:
cord-312119-wzcas4zd	125	43	Fuentes	Fuentes	NNPS
cord-312119-wzcas4zd	125	44	et	et	NNP
cord-312119-wzcas4zd	125	45	al	al	NNP
cord-312119-wzcas4zd	125	46	.	.	NNP
cord-312119-wzcas4zd	125	47	,	,	,
cord-312119-wzcas4zd	125	48	2004	2004	CD
cord-312119-wzcas4zd	125	49	Santiago	Santiago	NNP
cord-312119-wzcas4zd	125	50	-	-	HYPH
cord-312119-wzcas4zd	125	51	Mateo	Mateo	NNP
cord-312119-wzcas4zd	125	52	et	et	NNP
cord-312119-wzcas4zd	125	53	al	al	NNP
cord-312119-wzcas4zd	125	54	.	.	NNP
cord-312119-wzcas4zd	125	55	,	,	,
cord-312119-wzcas4zd	125	56	2012	2012	CD
cord-312119-wzcas4zd	125	57	.	.	.
cord-312119-wzcas4zd	126	1	However	however	RB
cord-312119-wzcas4zd	126	2	,	,	,
cord-312119-wzcas4zd	126	3	live	live	JJ
cord-312119-wzcas4zd	126	4	strains	strain	NNS
cord-312119-wzcas4zd	126	5	expressing	express	VBG
cord-312119-wzcas4zd	126	6	F18	F18	NNP
cord-312119-wzcas4zd	126	7	were	be	VBD
cord-312119-wzcas4zd	126	8	not	not	RB
cord-312119-wzcas4zd	126	9	effective	effective	JJ
cord-312119-wzcas4zd	126	10	in	in	IN
cord-312119-wzcas4zd	126	11	the	the	DT
cord-312119-wzcas4zd	126	12	induction	induction	NN
cord-312119-wzcas4zd	126	13	of	of	IN
cord-312119-wzcas4zd	126	14	an	an	DT
cord-312119-wzcas4zd	126	15	F18-specific	F18-specific	NNP
cord-312119-wzcas4zd	126	16	Fig	Fig	NNP
cord-312119-wzcas4zd	126	17	.	.	.
cord-312119-wzcas4zd	127	1	3	3	LS
cord-312119-wzcas4zd	127	2	.	.	.
cord-312119-wzcas4zd	128	1	Competitive	competitive	JJ
cord-312119-wzcas4zd	128	2	ELISA	ELISA	NNP
cord-312119-wzcas4zd	128	3	and	and	CC
cord-312119-wzcas4zd	128	4	bacteria	bacteria	NNS
cord-312119-wzcas4zd	128	5	adherence	adherence	NN
cord-312119-wzcas4zd	128	6	inhibition	inhibition	NN
cord-312119-wzcas4zd	128	7	assay	assay	NN
cord-312119-wzcas4zd	128	8	to	to	TO
cord-312119-wzcas4zd	128	9	show	show	VB
cord-312119-wzcas4zd	128	10	CfaB	cfab	NN
cord-312119-wzcas4zd	128	11	-	-	HYPH
cord-312119-wzcas4zd	128	12	epitope	epitope	NN
cord-312119-wzcas4zd	128	13	fusion	fusion	NN
cord-312119-wzcas4zd	128	14	proteins	protein	NNS
cord-312119-wzcas4zd	128	15	blocking	block	VBG
cord-312119-wzcas4zd	128	16	binding	binding	NN
cord-312119-wzcas4zd	128	17	of	of	IN
cord-312119-wzcas4zd	128	18	anti	anti	JJ
cord-312119-wzcas4zd	128	19	-	-	JJ
cord-312119-wzcas4zd	128	20	F18	f18	JJ
cord-312119-wzcas4zd	128	21	antiserum	antiserum	NN
cord-312119-wzcas4zd	128	22	with	with	IN
cord-312119-wzcas4zd	128	23	F18	F18	NNP
cord-312119-wzcas4zd	128	24	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	128	25	or	or	CC
cord-312119-wzcas4zd	128	26	F18-fimbrial	F18-fimbrial	NNP
cord-312119-wzcas4zd	128	27	E.	E.	NNP
cord-312119-wzcas4zd	128	28	coli	coli	NNS
cord-312119-wzcas4zd	128	29	bacteria	bacteria	NNS
cord-312119-wzcas4zd	128	30	8516	8516	CD
cord-312119-wzcas4zd	128	31	.	.	.
cord-312119-wzcas4zd	129	1	A	a	DT
cord-312119-wzcas4zd	129	2	:	:	:
cord-312119-wzcas4zd	129	3	competitive	competitive	JJ
cord-312119-wzcas4zd	129	4	ELISAs	elisa	NNS
cord-312119-wzcas4zd	129	5	with	with	IN
cord-312119-wzcas4zd	129	6	F18	F18	NNP
cord-312119-wzcas4zd	129	7	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	129	8	as	as	IN
cord-312119-wzcas4zd	129	9	the	the	DT
cord-312119-wzcas4zd	129	10	coating	coating	NN
cord-312119-wzcas4zd	129	11	antigen	antigen	NN
cord-312119-wzcas4zd	129	12	,	,	,
cord-312119-wzcas4zd	129	13	and	and	CC
cord-312119-wzcas4zd	129	14	each	each	DT
cord-312119-wzcas4zd	129	15	CfaB	cfab	NN
cord-312119-wzcas4zd	129	16	-	-	HYPH
cord-312119-wzcas4zd	129	17	epitope	epitope	NN
cord-312119-wzcas4zd	129	18	fusion	fusion	NN
cord-312119-wzcas4zd	129	19	protein	protein	NN
cord-312119-wzcas4zd	129	20	as	as	IN
cord-312119-wzcas4zd	129	21	the	the	DT
cord-312119-wzcas4zd	129	22	competing	compete	VBG
cord-312119-wzcas4zd	129	23	agent	agent	NN
cord-312119-wzcas4zd	129	24	.	.	.
cord-312119-wzcas4zd	130	1	Anti	anti	JJ
cord-312119-wzcas4zd	130	2	-	-	JJ
cord-312119-wzcas4zd	130	3	F18	f18	JJ
cord-312119-wzcas4zd	130	4	antiserum	antiserum	NN
cord-312119-wzcas4zd	130	5	dilutions	dilution	NNS
cord-312119-wzcas4zd	130	6	from	from	IN
cord-312119-wzcas4zd	130	7	1:4,000	1:4,000	CD
cord-312119-wzcas4zd	130	8	to	to	TO
cord-312119-wzcas4zd	130	9	1:32,000	1:32,000	CD
cord-312119-wzcas4zd	130	10	were	be	VBD
cord-312119-wzcas4zd	130	11	used	use	VBN
cord-312119-wzcas4zd	130	12	.	.	.
cord-312119-wzcas4zd	131	1	B	b	NN
cord-312119-wzcas4zd	131	2	:	:	:
cord-312119-wzcas4zd	132	1	antibody	antibody	NN
cord-312119-wzcas4zd	132	2	adherence	adherence	NN
cord-312119-wzcas4zd	132	3	inhibition	inhibition	NN
cord-312119-wzcas4zd	132	4	assay	assay	NN
cord-312119-wzcas4zd	132	5	using	use	VBG
cord-312119-wzcas4zd	132	6	anti	anti	JJ
cord-312119-wzcas4zd	132	7	-	-	JJ
cord-312119-wzcas4zd	132	8	F18	f18	JJ
cord-312119-wzcas4zd	132	9	antiserum	antiserum	NN
cord-312119-wzcas4zd	132	10	as	as	IN
cord-312119-wzcas4zd	132	11	the	the	DT
cord-312119-wzcas4zd	132	12	antibodies	antibody	NNS
cord-312119-wzcas4zd	132	13	to	to	TO
cord-312119-wzcas4zd	132	14	inhibit	inhibit	VB
cord-312119-wzcas4zd	132	15	F18fimbiral	F18fimbiral	NNP
cord-312119-wzcas4zd	132	16	E.	E.	NNP
cord-312119-wzcas4zd	132	17	coli	coli	NNS
cord-312119-wzcas4zd	132	18	strain	strain	NN
cord-312119-wzcas4zd	132	19	8516	8516	CD
cord-312119-wzcas4zd	132	20	binding	bind	VBG
cord-312119-wzcas4zd	132	21	to	to	IN
cord-312119-wzcas4zd	132	22	F-18	F-18	NNP
cord-312119-wzcas4zd	132	23	receptor	receptor	NN
cord-312119-wzcas4zd	132	24	positive	positive	JJ
cord-312119-wzcas4zd	132	25	pig	pig	NN
cord-312119-wzcas4zd	132	26	intestine	intestine	NN
cord-312119-wzcas4zd	132	27	cell	cell	NN
cord-312119-wzcas4zd	132	28	line	line	NN
cord-312119-wzcas4zd	132	29	IPEC	IPEC	NNP
cord-312119-wzcas4zd	132	30	-	-	HYPH
cord-312119-wzcas4zd	132	31	J2	J2	NNP
cord-312119-wzcas4zd	132	32	,	,	,
cord-312119-wzcas4zd	132	33	and	and	CC
cord-312119-wzcas4zd	132	34	each	each	DT
cord-312119-wzcas4zd	132	35	CfaB	cfab	NN
cord-312119-wzcas4zd	132	36	-	-	HYPH
cord-312119-wzcas4zd	132	37	epitope	epitope	NN
cord-312119-wzcas4zd	132	38	fusion	fusion	NN
cord-312119-wzcas4zd	132	39	protein	protein	NN
cord-312119-wzcas4zd	132	40	as	as	IN
cord-312119-wzcas4zd	132	41	the	the	DT
cord-312119-wzcas4zd	132	42	agent	agent	NN
cord-312119-wzcas4zd	132	43	to	to	TO
cord-312119-wzcas4zd	132	44	compete	compete	VB
cord-312119-wzcas4zd	132	45	for	for	IN
cord-312119-wzcas4zd	132	46	anti	anti	JJ
cord-312119-wzcas4zd	132	47	-	-	JJ
cord-312119-wzcas4zd	132	48	F18	f18	JJ
cord-312119-wzcas4zd	132	49	antiserum	antiserum	NN
cord-312119-wzcas4zd	132	50	thus	thus	RB
cord-312119-wzcas4zd	132	51	to	to	TO
cord-312119-wzcas4zd	132	52	prevent	prevent	VB
cord-312119-wzcas4zd	132	53	anti	anti	JJ
cord-312119-wzcas4zd	132	54	-	-	JJ
cord-312119-wzcas4zd	132	55	F18	f18	JJ
cord-312119-wzcas4zd	132	56	antiserum	antiserum	NN
cord-312119-wzcas4zd	132	57	from	from	IN
cord-312119-wzcas4zd	132	58	blocking	block	VBG
cord-312119-wzcas4zd	132	59	the	the	DT
cord-312119-wzcas4zd	132	60	binding	binding	NN
cord-312119-wzcas4zd	132	61	between	between	IN
cord-312119-wzcas4zd	132	62	8516	8516	CD
cord-312119-wzcas4zd	132	63	bacteria	bacteria	NNS
cord-312119-wzcas4zd	132	64	to	to	IN
cord-312119-wzcas4zd	132	65	OPEC	OPEC	NNP
cord-312119-wzcas4zd	132	66	-	-	HYPH
cord-312119-wzcas4zd	132	67	J2	J2	NNP
cord-312119-wzcas4zd	132	68	cells	cell	NNS
cord-312119-wzcas4zd	132	69	.	.	.
cord-312119-wzcas4zd	133	1	PBS	PBS	NNP
cord-312119-wzcas4zd	133	2	,	,	,
cord-312119-wzcas4zd	133	3	no	no	DT
cord-312119-wzcas4zd	133	4	competing	compete	VBG
cord-312119-wzcas4zd	133	5	agent	agent	NN
cord-312119-wzcas4zd	133	6	and	and	CC
cord-312119-wzcas4zd	133	7	no	no	DT
cord-312119-wzcas4zd	133	8	anti	anti	JJ
cord-312119-wzcas4zd	133	9	-	-	JJ
cord-312119-wzcas4zd	133	10	F18	f18	JJ
cord-312119-wzcas4zd	133	11	antiserum	antiserum	NN
cord-312119-wzcas4zd	133	12	;	;	:
cord-312119-wzcas4zd	133	13	control	control	NN
cord-312119-wzcas4zd	133	14	,	,	,
cord-312119-wzcas4zd	133	15	control	control	NN
cord-312119-wzcas4zd	133	16	mouse	mouse	NN
cord-312119-wzcas4zd	133	17	serum	serum	NN
cord-312119-wzcas4zd	133	18	only	only	RB
cord-312119-wzcas4zd	133	19	;	;	:
cord-312119-wzcas4zd	133	20	anti	anti	JJ
cord-312119-wzcas4zd	133	21	-	-	NNP
cord-312119-wzcas4zd	133	22	F18	f18	JJ
cord-312119-wzcas4zd	133	23	,	,	,
cord-312119-wzcas4zd	133	24	no	no	DT
cord-312119-wzcas4zd	133	25	competing	compete	VBG
cord-312119-wzcas4zd	133	26	agent	agent	NN
cord-312119-wzcas4zd	134	1	but	but	CC
cord-312119-wzcas4zd	134	2	with	with	IN
cord-312119-wzcas4zd	134	3	anti	anti	JJ
cord-312119-wzcas4zd	134	4	-	-	JJ
cord-312119-wzcas4zd	134	5	F18	f18	JJ
cord-312119-wzcas4zd	134	6	antiserum	antiserum	NN
cord-312119-wzcas4zd	134	7	.	.	.
cord-312119-wzcas4zd	135	1	Fig	Fig	NNP
cord-312119-wzcas4zd	135	2	.	.	NNP
cord-312119-wzcas4zd	135	3	4	4	CD
cord-312119-wzcas4zd	135	4	.	.	.
cord-312119-wzcas4zd	136	1	Mouse	mouse	NN
cord-312119-wzcas4zd	136	2	serum	serum	NN
cord-312119-wzcas4zd	136	3	anti	anti	JJ
cord-312119-wzcas4zd	136	4	-	-	JJ
cord-312119-wzcas4zd	136	5	F18	f18	JJ
cord-312119-wzcas4zd	136	6	antibody	antibody	NN
cord-312119-wzcas4zd	136	7	titration	titration	NN
cord-312119-wzcas4zd	136	8	and	and	CC
cord-312119-wzcas4zd	136	9	antibody	antibody	NN
cord-312119-wzcas4zd	136	10	adherence	adherence	NN
cord-312119-wzcas4zd	136	11	inhibition	inhibition	NN
cord-312119-wzcas4zd	136	12	assay	assay	NN
cord-312119-wzcas4zd	136	13	.	.	.
cord-312119-wzcas4zd	137	1	A	a	LS
cord-312119-wzcas4zd	137	2	:	:	:
cord-312119-wzcas4zd	137	3	anti	anti	JJ
cord-312119-wzcas4zd	137	4	-	-	JJ
cord-312119-wzcas4zd	137	5	F18	f18	JJ
cord-312119-wzcas4zd	137	6	IgG	igg	NN
cord-312119-wzcas4zd	137	7	titers	titer	NNS
cord-312119-wzcas4zd	137	8	(	(	-LRB-
cord-312119-wzcas4zd	137	9	in	in	IN
cord-312119-wzcas4zd	137	10	log	log	NN
cord-312119-wzcas4zd	137	11	10	10	CD
cord-312119-wzcas4zd	137	12	)	)	-RRB-
cord-312119-wzcas4zd	137	13	from	from	IN
cord-312119-wzcas4zd	137	14	serum	serum	NN
cord-312119-wzcas4zd	137	15	samples	sample	NNS
cord-312119-wzcas4zd	137	16	of	of	IN
cord-312119-wzcas4zd	137	17	the	the	DT
cord-312119-wzcas4zd	137	18	mice	mouse	NNS
cord-312119-wzcas4zd	137	19	immunized	immunize	VBN
cord-312119-wzcas4zd	137	20	with	with	IN
cord-312119-wzcas4zd	137	21	each	each	DT
cord-312119-wzcas4zd	137	22	CfaB	cfab	NN
cord-312119-wzcas4zd	137	23	-	-	HYPH
cord-312119-wzcas4zd	137	24	epitope	epitope	NN
cord-312119-wzcas4zd	137	25	fusion	fusion	NN
cord-312119-wzcas4zd	137	26	protein	protein	NN
cord-312119-wzcas4zd	137	27	;	;	.
cord-312119-wzcas4zd	138	1	no	no	DT
cord-312119-wzcas4zd	138	2	anti	anti	JJ
cord-312119-wzcas4zd	138	3	-	-	JJ
cord-312119-wzcas4zd	138	4	F18	f18	JJ
cord-312119-wzcas4zd	138	5	IgG	igg	NN
cord-312119-wzcas4zd	138	6	titer	titer	NN
cord-312119-wzcas4zd	138	7	detected	detect	VBD
cord-312119-wzcas4zd	138	8	from	from	IN
cord-312119-wzcas4zd	138	9	the	the	DT
cord-312119-wzcas4zd	138	10	negative	negative	JJ
cord-312119-wzcas4zd	138	11	control	control	NN
cord-312119-wzcas4zd	138	12	mice	mouse	NNS
cord-312119-wzcas4zd	138	13	.	.	.
cord-312119-wzcas4zd	139	1	B	b	NN
cord-312119-wzcas4zd	139	2	:	:	:
cord-312119-wzcas4zd	139	3	mouse	mouse	NN
cord-312119-wzcas4zd	139	4	serum	serum	NN
cord-312119-wzcas4zd	139	5	antibody	antibody	NN
cord-312119-wzcas4zd	139	6	inhibition	inhibition	NN
cord-312119-wzcas4zd	139	7	assays	assay	NNS
cord-312119-wzcas4zd	139	8	to	to	TO
cord-312119-wzcas4zd	139	9	show	show	VB
cord-312119-wzcas4zd	139	10	epitopederived	epitopederived	JJ
cord-312119-wzcas4zd	139	11	antibodies	antibody	NNS
cord-312119-wzcas4zd	139	12	against	against	IN
cord-312119-wzcas4zd	139	13	adherence	adherence	NN
cord-312119-wzcas4zd	139	14	(	(	-LRB-
cord-312119-wzcas4zd	139	15	in	in	IN
cord-312119-wzcas4zd	139	16	%	%	NN
cord-312119-wzcas4zd	139	17	)	)	-RRB-
cord-312119-wzcas4zd	139	18	of	of	IN
cord-312119-wzcas4zd	139	19	F-18	F-18	NNP
cord-312119-wzcas4zd	139	20	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	139	21	E.	E.	NNP
cord-312119-wzcas4zd	139	22	coli	coli	NNS
cord-312119-wzcas4zd	139	23	bacteria	bacteria	NNS
cord-312119-wzcas4zd	139	24	8561	8561	CD
cord-312119-wzcas4zd	139	25	to	to	IN
cord-312119-wzcas4zd	139	26	IPEC	IPEC	NNP
cord-312119-wzcas4zd	139	27	-	-	HYPH
cord-312119-wzcas4zd	139	28	J2	j2	NN
cord-312119-wzcas4zd	139	29	cells	cell	NNS
cord-312119-wzcas4zd	139	30	.	.	.
cord-312119-wzcas4zd	140	1	PBS	PBS	NNP
cord-312119-wzcas4zd	140	2	,	,	,
cord-312119-wzcas4zd	140	3	no	no	DT
cord-312119-wzcas4zd	140	4	mouse	mouse	NN
cord-312119-wzcas4zd	140	5	serum	serum	NN
cord-312119-wzcas4zd	140	6	;	;	:
cord-312119-wzcas4zd	140	7	control	control	NN
cord-312119-wzcas4zd	140	8	,	,	,
cord-312119-wzcas4zd	140	9	negative	negative	JJ
cord-312119-wzcas4zd	140	10	control	control	NN
cord-312119-wzcas4zd	140	11	mouse	mouse	NN
cord-312119-wzcas4zd	140	12	serum	serum	NN
cord-312119-wzcas4zd	140	13	;	;	:
cord-312119-wzcas4zd	140	14	anti	anti	JJ
cord-312119-wzcas4zd	140	15	-	-	NNP
cord-312119-wzcas4zd	140	16	F18	f18	JJ
cord-312119-wzcas4zd	140	17	,	,	,
cord-312119-wzcas4zd	140	18	serum	serum	NN
cord-312119-wzcas4zd	140	19	samples	sample	NNS
cord-312119-wzcas4zd	140	20	of	of	IN
cord-312119-wzcas4zd	140	21	mice	mouse	NNS
cord-312119-wzcas4zd	140	22	immunized	immunize	VBN
cord-312119-wzcas4zd	140	23	with	with	IN
cord-312119-wzcas4zd	140	24	F18	F18	NNP
cord-312119-wzcas4zd	140	25	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	140	26	.	.	.
cord-312119-wzcas4zd	141	1	T.	T.	NNP
cord-312119-wzcas4zd	141	2	Lu	Lu	NNP
cord-312119-wzcas4zd	141	3	et	et	FW
cord-312119-wzcas4zd	141	4	al	al	NNP
cord-312119-wzcas4zd	141	5	.	.	.
cord-312119-wzcas4zd	142	1	Veterinary	Veterinary	NNP
cord-312119-wzcas4zd	142	2	Microbiology	Microbiology	NNP
cord-312119-wzcas4zd	142	3	230	230	CD
cord-312119-wzcas4zd	142	4	(	(	-LRB-
cord-312119-wzcas4zd	142	5	2019	2019	CD
cord-312119-wzcas4zd	142	6	)	)	-RRB-
cord-312119-wzcas4zd	142	7	171	171	CD
cord-312119-wzcas4zd	142	8	-	-	SYM
cord-312119-wzcas4zd	142	9	177	177	CD
cord-312119-wzcas4zd	142	10	immune	immune	JJ
cord-312119-wzcas4zd	142	11	response	response	NN
cord-312119-wzcas4zd	142	12	,	,	,
cord-312119-wzcas4zd	142	13	nor	nor	CC
cord-312119-wzcas4zd	142	14	protective	protective	JJ
cord-312119-wzcas4zd	142	15	against	against	IN
cord-312119-wzcas4zd	142	16	challenge	challenge	NN
cord-312119-wzcas4zd	142	17	with	with	IN
cord-312119-wzcas4zd	142	18	an	an	DT
cord-312119-wzcas4zd	142	19	F18	F18	NNP
cord-312119-wzcas4zd	142	20	ETEC	etec	JJ
cord-312119-wzcas4zd	142	21	strain	strain	NN
cord-312119-wzcas4zd	142	22	(	(	-LRB-
cord-312119-wzcas4zd	142	23	Bertschinger	Bertschinger	NNP
cord-312119-wzcas4zd	142	24	et	et	NNP
cord-312119-wzcas4zd	142	25	al	al	NNP
cord-312119-wzcas4zd	142	26	.	.	NNP
cord-312119-wzcas4zd	142	27	,	,	,
cord-312119-wzcas4zd	142	28	2000	2000	CD
cord-312119-wzcas4zd	142	29	;	;	:
cord-312119-wzcas4zd	142	30	Coddens	Coddens	NNP
cord-312119-wzcas4zd	142	31	et	et	NNP
cord-312119-wzcas4zd	142	32	al	al	NNP
cord-312119-wzcas4zd	142	33	.	.	NNP
cord-312119-wzcas4zd	142	34	,	,	,
cord-312119-wzcas4zd	142	35	2007	2007	CD
cord-312119-wzcas4zd	142	36	)	)	-RRB-
cord-312119-wzcas4zd	142	37	.	.	.
cord-312119-wzcas4zd	143	1	F18	F18	NNP
cord-312119-wzcas4zd	143	2	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	143	3	,	,	,
cord-312119-wzcas4zd	143	4	previously	previously	RB
cord-312119-wzcas4zd	143	5	known	know	VBN
cord-312119-wzcas4zd	143	6	as	as	IN
cord-312119-wzcas4zd	143	7	F107	F107	NNP
cord-312119-wzcas4zd	143	8	,	,	,
cord-312119-wzcas4zd	143	9	2134	2134	CD
cord-312119-wzcas4zd	143	10	P	p	NN
cord-312119-wzcas4zd	143	11	and	and	CC
cord-312119-wzcas4zd	143	12	8813	8813	CD
cord-312119-wzcas4zd	143	13	,	,	,
cord-312119-wzcas4zd	143	14	consist	consist	VBP
cord-312119-wzcas4zd	143	15	of	of	IN
cord-312119-wzcas4zd	143	16	two	two	CD
cord-312119-wzcas4zd	143	17	antigenic	antigenic	JJ
cord-312119-wzcas4zd	143	18	variants	variant	NNS
cord-312119-wzcas4zd	143	19	:	:	:
cord-312119-wzcas4zd	144	1	F18ac	F18ac	NNP
cord-312119-wzcas4zd	144	2	and	and	CC
cord-312119-wzcas4zd	144	3	F18ab	F18ab	NNP
cord-312119-wzcas4zd	144	4	Nagy	Nagy	NNP
cord-312119-wzcas4zd	144	5	et	et	NNP
cord-312119-wzcas4zd	144	6	al	al	NNP
cord-312119-wzcas4zd	144	7	.	.	NNP
cord-312119-wzcas4zd	144	8	,	,	,
cord-312119-wzcas4zd	144	9	1997	1997	CD
cord-312119-wzcas4zd	144	10	)	)	-RRB-
cord-312119-wzcas4zd	144	11	,	,	,
cord-312119-wzcas4zd	144	12	and	and	CC
cord-312119-wzcas4zd	144	13	are	be	VBP
cord-312119-wzcas4zd	144	14	associated	associate	VBN
cord-312119-wzcas4zd	144	15	with	with	IN
cord-312119-wzcas4zd	144	16	PWD	pwd	NN
cord-312119-wzcas4zd	144	17	and	and	CC
cord-312119-wzcas4zd	144	18	edema	edema	NN
cord-312119-wzcas4zd	144	19	disease	disease	NN
cord-312119-wzcas4zd	144	20	in	in	IN
cord-312119-wzcas4zd	144	21	young	young	JJ
cord-312119-wzcas4zd	144	22	pigs	pig	NNS
cord-312119-wzcas4zd	144	23	respectively	respectively	RB
cord-312119-wzcas4zd	144	24	(	(	-LRB-
cord-312119-wzcas4zd	144	25	Amezcua	Amezcua	NNP
cord-312119-wzcas4zd	144	26	et	et	FW
cord-312119-wzcas4zd	144	27	al	al	NNP
cord-312119-wzcas4zd	144	28	.	.	NNP
cord-312119-wzcas4zd	144	29	,	,	,
cord-312119-wzcas4zd	144	30	2002	2002	CD
cord-312119-wzcas4zd	144	31	;	;	:
cord-312119-wzcas4zd	144	32	Frydendahl	Frydendahl	NNPS
cord-312119-wzcas4zd	144	33	,	,	,
cord-312119-wzcas4zd	144	34	2002	2002	CD
cord-312119-wzcas4zd	144	35	;	;	:
cord-312119-wzcas4zd	144	36	Osek	Osek	NNP
cord-312119-wzcas4zd	144	37	,	,	,
cord-312119-wzcas4zd	144	38	1999a	1999a	CD
cord-312119-wzcas4zd	144	39	;	;	:
cord-312119-wzcas4zd	144	40	Post	Post	NNP
cord-312119-wzcas4zd	144	41	et	et	FW
cord-312119-wzcas4zd	144	42	al	al	NNP
cord-312119-wzcas4zd	144	43	.	.	NNP
cord-312119-wzcas4zd	144	44	,	,	,
cord-312119-wzcas4zd	144	45	2000	2000	CD
cord-312119-wzcas4zd	144	46	)	)	-RRB-
cord-312119-wzcas4zd	144	47	.	.	.
cord-312119-wzcas4zd	145	1	The	the	DT
cord-312119-wzcas4zd	145	2	major	major	JJ
cord-312119-wzcas4zd	145	3	structural	structural	JJ
cord-312119-wzcas4zd	145	4	subunit	subunit	NN
cord-312119-wzcas4zd	145	5	of	of	IN
cord-312119-wzcas4zd	145	6	F18	F18	NNP
cord-312119-wzcas4zd	145	7	is	be	VBZ
cord-312119-wzcas4zd	145	8	FedA	FedA	NNP
cord-312119-wzcas4zd	145	9	,	,	,
cord-312119-wzcas4zd	145	10	but	but	CC
cord-312119-wzcas4zd	145	11	the	the	DT
cord-312119-wzcas4zd	145	12	adhesive	adhesive	JJ
cord-312119-wzcas4zd	145	13	minor	minor	JJ
cord-312119-wzcas4zd	145	14	subunit	subunit	NN
cord-312119-wzcas4zd	145	15	FedF	FedF	NNP
cord-312119-wzcas4zd	145	16	plays	play	VBZ
cord-312119-wzcas4zd	145	17	a	a	DT
cord-312119-wzcas4zd	145	18	central	central	JJ
cord-312119-wzcas4zd	145	19	role	role	NN
cord-312119-wzcas4zd	145	20	in	in	IN
cord-312119-wzcas4zd	145	21	binding	bind	VBG
cord-312119-wzcas4zd	145	22	to	to	IN
cord-312119-wzcas4zd	145	23	host	host	VB
cord-312119-wzcas4zd	145	24	receptors	receptor	NNS
cord-312119-wzcas4zd	146	1	(	(	-LRB-
cord-312119-wzcas4zd	146	2	Imberechts	Imberechts	NNP
cord-312119-wzcas4zd	146	3	et	et	NNP
cord-312119-wzcas4zd	146	4	al	al	NNP
cord-312119-wzcas4zd	146	5	.	.	NNP
cord-312119-wzcas4zd	146	6	,	,	,
cord-312119-wzcas4zd	146	7	1996	1996	CD
cord-312119-wzcas4zd	147	1	;	;	:
cord-312119-wzcas4zd	147	2	Smeds	Smeds	NNP
cord-312119-wzcas4zd	147	3	et	et	NNP
cord-312119-wzcas4zd	147	4	al	al	NNP
cord-312119-wzcas4zd	147	5	.	.	.
cord-312119-wzcas4zd	148	1	,	,	,
cord-312119-wzcas4zd	148	2	2001	2001	CD
cord-312119-wzcas4zd	149	1	Smeds	Smeds	NNP
cord-312119-wzcas4zd	149	2	et	et	NNP
cord-312119-wzcas4zd	149	3	al	al	NNP
cord-312119-wzcas4zd	149	4	.	.	NNP
cord-312119-wzcas4zd	149	5	,	,	,
cord-312119-wzcas4zd	149	6	,	,	,
cord-312119-wzcas4zd	149	7	2003	2003	CD
cord-312119-wzcas4zd	149	8	,	,	,
cord-312119-wzcas4zd	149	9	and	and	CC
cord-312119-wzcas4zd	149	10	is	be	VBZ
cord-312119-wzcas4zd	149	11	highly	highly	RB
cord-312119-wzcas4zd	149	12	conserved	conserve	VBN
cord-312119-wzcas4zd	149	13	among	among	IN
cord-312119-wzcas4zd	149	14	F18	f18	JJ
cord-312119-wzcas4zd	149	15	strains	strain	NNS
cord-312119-wzcas4zd	149	16	.	.	.
cord-312119-wzcas4zd	150	1	A	a	DT
cord-312119-wzcas4zd	150	2	LT	LT	NNP
cord-312119-wzcas4zd	150	3	-	-	HYPH
cord-312119-wzcas4zd	150	4	K88-F18	K88-F18	NNP
cord-312119-wzcas4zd	150	5	tripartite	tripartite	JJ
cord-312119-wzcas4zd	150	6	antigen	antigen	NN
cord-312119-wzcas4zd	150	7	that	that	WDT
cord-312119-wzcas4zd	150	8	includes	include	VBZ
cord-312119-wzcas4zd	150	9	FedF	FedF	NNP
cord-312119-wzcas4zd	150	10	peptide	peptide	NN
cord-312119-wzcas4zd	150	11	(	(	-LRB-
cord-312119-wzcas4zd	150	12	60	60	CD
cord-312119-wzcas4zd	150	13	th	th	XX
cord-312119-wzcas4zd	150	14	-109	-109	NN
cord-312119-wzcas4zd	150	15	th	th	XX
cord-312119-wzcas4zd	150	16	aa	aa	NNP
cord-312119-wzcas4zd	150	17	)	)	-RRB-
cord-312119-wzcas4zd	150	18	,	,	,
cord-312119-wzcas4zd	150	19	as	as	IN
cord-312119-wzcas4zd	150	20	a	a	DT
cord-312119-wzcas4zd	150	21	recombinant	recombinant	JJ
cord-312119-wzcas4zd	150	22	protein	protein	NN
cord-312119-wzcas4zd	150	23	administered	administer	VBN
cord-312119-wzcas4zd	150	24	intramuscularly	intramuscularly	RB
cord-312119-wzcas4zd	151	1	(	(	-LRB-
cord-312119-wzcas4zd	151	2	Ruan	Ruan	NNP
cord-312119-wzcas4zd	151	3	et	et	NNP
cord-312119-wzcas4zd	151	4	al	al	NNP
cord-312119-wzcas4zd	151	5	.	.	NNP
cord-312119-wzcas4zd	151	6	,	,	,
cord-312119-wzcas4zd	151	7	2011	2011	CD
cord-312119-wzcas4zd	151	8	)	)	-RRB-
cord-312119-wzcas4zd	151	9	or	or	CC
cord-312119-wzcas4zd	151	10	a	a	DT
cord-312119-wzcas4zd	151	11	holotoxin	holotoxin	JJ
cord-312119-wzcas4zd	151	12	-	-	HYPH
cord-312119-wzcas4zd	151	13	structured	structure	VBN
cord-312119-wzcas4zd	151	14	protein	protein	NN
cord-312119-wzcas4zd	151	15	expressed	express	VBN
cord-312119-wzcas4zd	151	16	by	by	IN
cord-312119-wzcas4zd	151	17	a	a	DT
cord-312119-wzcas4zd	151	18	live	live	JJ
cord-312119-wzcas4zd	151	19	E.	E.	NNP
cord-312119-wzcas4zd	151	20	coli	coli	NNS
cord-312119-wzcas4zd	151	21	strain	strain	NN
cord-312119-wzcas4zd	151	22	when	when	WRB
cord-312119-wzcas4zd	151	23	given	give	VBN
cord-312119-wzcas4zd	151	24	orally	orally	RB
cord-312119-wzcas4zd	151	25	(	(	-LRB-
cord-312119-wzcas4zd	151	26	Ruan	Ruan	NNP
cord-312119-wzcas4zd	151	27	and	and	CC
cord-312119-wzcas4zd	151	28	Zhang	Zhang	NNP
cord-312119-wzcas4zd	151	29	,	,	,
cord-312119-wzcas4zd	151	30	2013	2013	CD
cord-312119-wzcas4zd	151	31	)	)	-RRB-
cord-312119-wzcas4zd	151	32	,	,	,
cord-312119-wzcas4zd	151	33	induced	induce	VBN
cord-312119-wzcas4zd	151	34	antibodies	antibody	NNS
cord-312119-wzcas4zd	151	35	blocking	block	VBG
cord-312119-wzcas4zd	151	36	adherence	adherence	NN
cord-312119-wzcas4zd	151	37	of	of	IN
cord-312119-wzcas4zd	151	38	K88-and	k88-and	NN
cord-312119-wzcas4zd	152	1	F18-fimbrial	f18-fimbrial	JJ
cord-312119-wzcas4zd	152	2	ETEC	etec	JJ
cord-312119-wzcas4zd	152	3	bacteria	bacteria	NNS
cord-312119-wzcas4zd	152	4	and	and	CC
cord-312119-wzcas4zd	152	5	protecting	protect	VBG
cord-312119-wzcas4zd	152	6	pigs	pig	NNS
cord-312119-wzcas4zd	152	7	against	against	IN
cord-312119-wzcas4zd	152	8	K88-fimbrial	k88-fimbrial	JJ
cord-312119-wzcas4zd	152	9	ETEC	etec	JJ
cord-312119-wzcas4zd	152	10	challenge	challenge	NN
cord-312119-wzcas4zd	152	11	.	.	.
cord-312119-wzcas4zd	153	1	This	this	DT
cord-312119-wzcas4zd	153	2	tripartite	tripartite	JJ
cord-312119-wzcas4zd	153	3	PWD	pwd	NN
cord-312119-wzcas4zd	153	4	vaccine	vaccine	NN
cord-312119-wzcas4zd	153	5	candidate	candidate	NN
cord-312119-wzcas4zd	153	6	was	be	VBD
cord-312119-wzcas4zd	153	7	not	not	RB
cord-312119-wzcas4zd	153	8	examined	examine	VBN
cord-312119-wzcas4zd	153	9	for	for	IN
cord-312119-wzcas4zd	153	10	efficacy	efficacy	NN
cord-312119-wzcas4zd	153	11	against	against	IN
cord-312119-wzcas4zd	153	12	F18-fimbrial	f18-fimbrial	JJ
cord-312119-wzcas4zd	153	13	ETEC	etec	JJ
cord-312119-wzcas4zd	153	14	challenge	challenge	NN
cord-312119-wzcas4zd	153	15	due	due	JJ
cord-312119-wzcas4zd	153	16	to	to	IN
cord-312119-wzcas4zd	153	17	difficulty	difficulty	NN
cord-312119-wzcas4zd	153	18	in	in	IN
cord-312119-wzcas4zd	153	19	identifying	identify	VBG
cord-312119-wzcas4zd	153	20	F18	f18	JJ
cord-312119-wzcas4zd	153	21	susceptible	susceptible	JJ
cord-312119-wzcas4zd	153	22	pigs	pig	NNS
cord-312119-wzcas4zd	153	23	,	,	,
cord-312119-wzcas4zd	153	24	and	and	CC
cord-312119-wzcas4zd	153	25	also	also	RB
cord-312119-wzcas4zd	153	26	needs	need	VBZ
cord-312119-wzcas4zd	153	27	to	to	TO
cord-312119-wzcas4zd	153	28	carry	carry	VB
cord-312119-wzcas4zd	153	29	toxin	toxin	NN
cord-312119-wzcas4zd	153	30	antigens	antigen	NNS
cord-312119-wzcas4zd	153	31	to	to	TO
cord-312119-wzcas4zd	153	32	induce	induce	VB
cord-312119-wzcas4zd	153	33	protective	protective	JJ
cord-312119-wzcas4zd	153	34	antitoxin	antitoxin	NN
cord-312119-wzcas4zd	153	35	antibodies	antibody	NNS
cord-312119-wzcas4zd	153	36	for	for	IN
cord-312119-wzcas4zd	153	37	effective	effective	JJ
cord-312119-wzcas4zd	153	38	protection	protection	NN
cord-312119-wzcas4zd	153	39	against	against	IN
cord-312119-wzcas4zd	153	40	PWD	PWD	NNP
cord-312119-wzcas4zd	153	41	.	.	.
cord-312119-wzcas4zd	154	1	Incorporating	incorporate	VBG
cord-312119-wzcas4zd	154	2	antigenic	antigenic	JJ
cord-312119-wzcas4zd	154	3	elements	element	NNS
cord-312119-wzcas4zd	154	4	of	of	IN
cord-312119-wzcas4zd	154	5	all	all	DT
cord-312119-wzcas4zd	154	6	virulence	virulence	NN
cord-312119-wzcas4zd	154	7	determinants	determinant	NNS
cord-312119-wzcas4zd	154	8	into	into	IN
cord-312119-wzcas4zd	154	9	a	a	DT
cord-312119-wzcas4zd	154	10	PWD	pwd	NN
cord-312119-wzcas4zd	154	11	vaccine	vaccine	NN
cord-312119-wzcas4zd	154	12	product	product	NN
cord-312119-wzcas4zd	154	13	for	for	IN
cord-312119-wzcas4zd	154	14	effective	effective	JJ
cord-312119-wzcas4zd	154	15	protection	protection	NN
cord-312119-wzcas4zd	154	16	against	against	IN
cord-312119-wzcas4zd	154	17	heterogeneous	heterogeneous	JJ
cord-312119-wzcas4zd	154	18	ETEC	etec	JJ
cord-312119-wzcas4zd	154	19	strains	strain	NNS
cord-312119-wzcas4zd	154	20	is	be	VBZ
cord-312119-wzcas4zd	154	21	challenging	challenging	JJ
cord-312119-wzcas4zd	154	22	.	.	.
cord-312119-wzcas4zd	155	1	Structural	structural	JJ
cord-312119-wzcas4zd	155	2	based	base	VBN
cord-312119-wzcas4zd	155	3	MEFA	MEFA	NNP
cord-312119-wzcas4zd	155	4	platform	platform	NN
cord-312119-wzcas4zd	155	5	allows	allow	VBZ
cord-312119-wzcas4zd	155	6	a	a	DT
cord-312119-wzcas4zd	155	7	backbone	backbone	NN
cord-312119-wzcas4zd	155	8	immunogen	immunogen	NN
cord-312119-wzcas4zd	155	9	to	to	TO
cord-312119-wzcas4zd	155	10	present	present	VB
cord-312119-wzcas4zd	155	11	multiple	multiple	JJ
cord-312119-wzcas4zd	155	12	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	155	13	epitopes	epitope	NNS
cord-312119-wzcas4zd	155	14	for	for	IN
cord-312119-wzcas4zd	155	15	broad	broad	JJ
cord-312119-wzcas4zd	155	16	immunity	immunity	NN
cord-312119-wzcas4zd	155	17	.	.	.
cord-312119-wzcas4zd	156	1	With	with	IN
cord-312119-wzcas4zd	156	2	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	156	3	epitopes	epitope	NNS
cord-312119-wzcas4zd	156	4	from	from	IN
cord-312119-wzcas4zd	156	5	K88	K88	NNP
cord-312119-wzcas4zd	156	6	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	156	7	adhesin	adhesin	NN
cord-312119-wzcas4zd	156	8	subunit	subunit	NN
cord-312119-wzcas4zd	156	9	FaeG	FaeG	NNP
cord-312119-wzcas4zd	156	10	,	,	,
cord-312119-wzcas4zd	156	11	toxins	toxin	NNS
cord-312119-wzcas4zd	156	12	including	include	VBG
cord-312119-wzcas4zd	156	13	LT	LT	NNP
cord-312119-wzcas4zd	156	14	,	,	,
cord-312119-wzcas4zd	156	15	STa	sta	NN
cord-312119-wzcas4zd	156	16	and	and	CC
cord-312119-wzcas4zd	156	17	STb	STb	NNS
cord-312119-wzcas4zd	156	18	are	be	VBP
cord-312119-wzcas4zd	156	19	already	already	RB
cord-312119-wzcas4zd	156	20	identified	identify	VBN
cord-312119-wzcas4zd	156	21	,	,	,
cord-312119-wzcas4zd	156	22	we	-PRON-	PRP
cord-312119-wzcas4zd	156	23	need	need	VBP
cord-312119-wzcas4zd	156	24	to	to	TO
cord-312119-wzcas4zd	156	25	identify	identify	VB
cord-312119-wzcas4zd	156	26	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	156	27	epitopes	epitope	NNS
cord-312119-wzcas4zd	156	28	from	from	IN
cord-312119-wzcas4zd	156	29	F18	F18	NNP
cord-312119-wzcas4zd	156	30	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	156	31	adhesin	adhesin	NN
cord-312119-wzcas4zd	156	32	subunit	subunit	NN
cord-312119-wzcas4zd	156	33	FedF	FedF	NNP
cord-312119-wzcas4zd	156	34	in	in	IN
cord-312119-wzcas4zd	156	35	order	order	NN
cord-312119-wzcas4zd	156	36	to	to	TO
cord-312119-wzcas4zd	156	37	have	have	VB
cord-312119-wzcas4zd	156	38	a	a	DT
cord-312119-wzcas4zd	156	39	PWD	pwd	NN
cord-312119-wzcas4zd	156	40	vaccine	vaccine	NN
cord-312119-wzcas4zd	156	41	candidate	candidate	NN
cord-312119-wzcas4zd	156	42	for	for	IN
cord-312119-wzcas4zd	156	43	immunity	immunity	NN
cord-312119-wzcas4zd	156	44	against	against	IN
cord-312119-wzcas4zd	156	45	all	all	DT
cord-312119-wzcas4zd	156	46	ETEC	etec	JJ
cord-312119-wzcas4zd	156	47	virulence	virulence	NN
cord-312119-wzcas4zd	156	48	determinants	determinant	NNS
cord-312119-wzcas4zd	156	49	.	.	.
cord-312119-wzcas4zd	157	1	Results	result	NNS
cord-312119-wzcas4zd	157	2	from	from	IN
cord-312119-wzcas4zd	157	3	the	the	DT
cord-312119-wzcas4zd	157	4	current	current	JJ
cord-312119-wzcas4zd	157	5	study	study	NN
cord-312119-wzcas4zd	157	6	indicated	indicate	VBD
cord-312119-wzcas4zd	157	7	that	that	IN
cord-312119-wzcas4zd	157	8	epitope	epitope	NN
cord-312119-wzcas4zd	157	9	#	#	NN
cord-312119-wzcas4zd	157	10	3	3	CD
cord-312119-wzcas4zd	157	11	(	(	-LRB-
cord-312119-wzcas4zd	157	12	IPSSGTLTCQAGT	IPSSGTLTCQAGT	NNP
cord-312119-wzcas4zd	157	13	)	)	-RRB-
cord-312119-wzcas4zd	157	14	and	and	CC
cord-312119-wzcas4zd	157	15	epitope	epitope	NN
cord-312119-wzcas4zd	157	16	#	#	$
cord-312119-wzcas4zd	157	17	7	7	CD
cord-312119-wzcas4zd	157	18	(	(	-LRB-
cord-312119-wzcas4zd	157	19	QPDA	QPDA	NNP
cord-312119-wzcas4zd	157	20	-	-	HYPH
cord-312119-wzcas4zd	157	21	TGSWYD	TGSWYD	NNP
cord-312119-wzcas4zd	157	22	)	)	-RRB-
cord-312119-wzcas4zd	157	23	are	be	VBP
cord-312119-wzcas4zd	157	24	the	the	DT
cord-312119-wzcas4zd	157	25	top	top	JJ
cord-312119-wzcas4zd	157	26	candidates	candidate	NNS
cord-312119-wzcas4zd	157	27	of	of	IN
cord-312119-wzcas4zd	157	28	F18	f18	JJ
cord-312119-wzcas4zd	157	29	adhesin	adhesin	NN
cord-312119-wzcas4zd	157	30	subunit	subunit	NN
cord-312119-wzcas4zd	157	31	FedF	FedF	NNP
cord-312119-wzcas4zd	157	32	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	157	33	epitopes	epitope	NNS
cord-312119-wzcas4zd	157	34	.	.	.
cord-312119-wzcas4zd	158	1	Imbedding	imbed	VBG
cord-312119-wzcas4zd	158	2	these	these	DT
cord-312119-wzcas4zd	158	3	two	two	CD
cord-312119-wzcas4zd	158	4	FedF	FedF	NNP
cord-312119-wzcas4zd	158	5	epitopes	epitope	NNS
cord-312119-wzcas4zd	158	6	into	into	IN
cord-312119-wzcas4zd	158	7	a	a	DT
cord-312119-wzcas4zd	158	8	MEFA	MEFA	NNP
cord-312119-wzcas4zd	158	9	that	that	WDT
cord-312119-wzcas4zd	158	10	uses	use	VBZ
cord-312119-wzcas4zd	158	11	a	a	DT
cord-312119-wzcas4zd	158	12	LT	LT	NNP
cord-312119-wzcas4zd	158	13	toxoid	toxoid	NN
cord-312119-wzcas4zd	158	14	as	as	IN
cord-312119-wzcas4zd	158	15	backbone	backbone	NN
cord-312119-wzcas4zd	158	16	and	and	CC
cord-312119-wzcas4zd	158	17	presents	present	VBZ
cord-312119-wzcas4zd	158	18	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	158	19	epitopes	epitope	NNS
cord-312119-wzcas4zd	158	20	of	of	IN
cord-312119-wzcas4zd	158	21	F18	F18	NNP
cord-312119-wzcas4zd	158	22	,	,	,
cord-312119-wzcas4zd	158	23	LT	LT	NNP
cord-312119-wzcas4zd	158	24	,	,	,
cord-312119-wzcas4zd	158	25	STa	sta	NN
cord-312119-wzcas4zd	158	26	and	and	CC
cord-312119-wzcas4zd	158	27	STb	STb	NNS
cord-312119-wzcas4zd	158	28	,	,	,
cord-312119-wzcas4zd	158	29	we	-PRON-	PRP
cord-312119-wzcas4zd	158	30	are	be	VBP
cord-312119-wzcas4zd	158	31	a	a	DT
cord-312119-wzcas4zd	158	32	step	step	NN
cord-312119-wzcas4zd	158	33	closer	close	RBR
cord-312119-wzcas4zd	158	34	for	for	IN
cord-312119-wzcas4zd	158	35	a	a	DT
cord-312119-wzcas4zd	158	36	broadly	broadly	RB
cord-312119-wzcas4zd	158	37	protective	protective	JJ
cord-312119-wzcas4zd	158	38	PWD	pwd	NN
cord-312119-wzcas4zd	158	39	vaccine	vaccine	NN
cord-312119-wzcas4zd	158	40	,	,	,
cord-312119-wzcas4zd	158	41	though	though	IN
cord-312119-wzcas4zd	158	42	future	future	JJ
cord-312119-wzcas4zd	158	43	challenge	challenge	NN
cord-312119-wzcas4zd	158	44	studies	study	NNS
cord-312119-wzcas4zd	158	45	are	be	VBP
cord-312119-wzcas4zd	158	46	needed	need	VBN
cord-312119-wzcas4zd	158	47	to	to	TO
cord-312119-wzcas4zd	158	48	confirm	confirm	VB
cord-312119-wzcas4zd	158	49	whether	whether	IN
cord-312119-wzcas4zd	158	50	antibodies	antibody	NNS
cord-312119-wzcas4zd	158	51	derived	derive	VBN
cord-312119-wzcas4zd	158	52	from	from	IN
cord-312119-wzcas4zd	158	53	these	these	DT
cord-312119-wzcas4zd	158	54	FedF	FedF	NNP
cord-312119-wzcas4zd	158	55	epitopes	epitope	NNS
cord-312119-wzcas4zd	158	56	are	be	VBP
cord-312119-wzcas4zd	158	57	protective	protective	JJ
cord-312119-wzcas4zd	158	58	against	against	IN
cord-312119-wzcas4zd	158	59	F18	F18	NNP
cord-312119-wzcas4zd	158	60	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	158	61	attachment	attachment	NN
cord-312119-wzcas4zd	158	62	and	and	CC
cord-312119-wzcas4zd	158	63	colonization	colonization	NN
cord-312119-wzcas4zd	158	64	.	.	.
cord-312119-wzcas4zd	159	1	In	in	IN
cord-312119-wzcas4zd	159	2	conclusion	conclusion	NN
cord-312119-wzcas4zd	159	3	,	,	,
cord-312119-wzcas4zd	159	4	seven	seven	CD
cord-312119-wzcas4zd	159	5	epitopes	epitope	NNS
cord-312119-wzcas4zd	159	6	identified	identify	VBN
cord-312119-wzcas4zd	159	7	from	from	IN
cord-312119-wzcas4zd	159	8	F18	F18	NNP
cord-312119-wzcas4zd	159	9	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	159	10	adhesin	adhesin	NN
cord-312119-wzcas4zd	159	11	subunit	subunit	NN
cord-312119-wzcas4zd	159	12	FedF	FedF	NNP
cord-312119-wzcas4zd	159	13	retained	retain	VBD
cord-312119-wzcas4zd	159	14	native	native	JJ
cord-312119-wzcas4zd	159	15	antigenicity	antigenicity	NN
cord-312119-wzcas4zd	159	16	after	after	IN
cord-312119-wzcas4zd	159	17	being	be	VBG
cord-312119-wzcas4zd	159	18	fused	fuse	VBN
cord-312119-wzcas4zd	159	19	to	to	IN
cord-312119-wzcas4zd	159	20	heterologous	heterologous	JJ
cord-312119-wzcas4zd	159	21	carrier	carrier	NN
cord-312119-wzcas4zd	159	22	CfaB	CfaB	NNP
cord-312119-wzcas4zd	159	23	protein	protein	NN
cord-312119-wzcas4zd	159	24	,	,	,
cord-312119-wzcas4zd	159	25	indicated	indicate	VBN
cord-312119-wzcas4zd	159	26	by	by	IN
cord-312119-wzcas4zd	159	27	each	each	DT
cord-312119-wzcas4zd	159	28	epitope	epitope	NN
cord-312119-wzcas4zd	159	29	fusion	fusion	NN
cord-312119-wzcas4zd	159	30	protein	protein	NN
cord-312119-wzcas4zd	159	31	recognized	recognize	VBN
cord-312119-wzcas4zd	159	32	by	by	IN
cord-312119-wzcas4zd	159	33	anti	anti	JJ
cord-312119-wzcas4zd	159	34	-	-	JJ
cord-312119-wzcas4zd	159	35	F18	f18	JJ
cord-312119-wzcas4zd	159	36	antiserum	antiserum	NN
cord-312119-wzcas4zd	159	37	but	but	CC
cord-312119-wzcas4zd	159	38	also	also	RB
cord-312119-wzcas4zd	159	39	ability	ability	VBP
cord-312119-wzcas4zd	159	40	to	to	TO
cord-312119-wzcas4zd	159	41	compete	compete	VB
cord-312119-wzcas4zd	159	42	with	with	IN
cord-312119-wzcas4zd	159	43	F18	F18	NNP
cord-312119-wzcas4zd	159	44	fimbria	fimbria	NN
cord-312119-wzcas4zd	159	45	for	for	IN
cord-312119-wzcas4zd	159	46	binding	bind	VBG
cord-312119-wzcas4zd	159	47	to	to	IN
cord-312119-wzcas4zd	159	48	anti	anti	JJ
cord-312119-wzcas4zd	159	49	-	-	JJ
cord-312119-wzcas4zd	159	50	F18	f18	JJ
cord-312119-wzcas4zd	159	51	antibodies	antibody	NNS
cord-312119-wzcas4zd	159	52	or	or	CC
cord-312119-wzcas4zd	159	53	to	to	TO
cord-312119-wzcas4zd	159	54	reduce	reduce	VB
cord-312119-wzcas4zd	159	55	anti-18	anti-18	NN
cord-312119-wzcas4zd	159	56	antibodies	antibody	NNS
cord-312119-wzcas4zd	159	57	from	from	IN
cord-312119-wzcas4zd	159	58	inhibiting	inhibit	VBG
cord-312119-wzcas4zd	159	59	adherence	adherence	NN
cord-312119-wzcas4zd	159	60	of	of	IN
cord-312119-wzcas4zd	159	61	E.	E.	NNP
cord-312119-wzcas4zd	159	62	coli	coli	NNS
cord-312119-wzcas4zd	159	63	bacteria	bacteria	NNS
cord-312119-wzcas4zd	159	64	expressing	express	VBG
cord-312119-wzcas4zd	159	65	F18	F18	NNP
cord-312119-wzcas4zd	159	66	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	159	67	.	.	.
cord-312119-wzcas4zd	160	1	Moreover	moreover	RB
cord-312119-wzcas4zd	160	2	,	,	,
cord-312119-wzcas4zd	160	3	each	each	DT
cord-312119-wzcas4zd	160	4	CfaB	cfab	NN
cord-312119-wzcas4zd	160	5	-	-	HYPH
cord-312119-wzcas4zd	160	6	epitope	epitope	NN
cord-312119-wzcas4zd	160	7	fusion	fusion	NN
cord-312119-wzcas4zd	160	8	protein	protein	NN
cord-312119-wzcas4zd	160	9	induced	induce	VBD
cord-312119-wzcas4zd	160	10	antibodies	antibody	NNS
cord-312119-wzcas4zd	160	11	specific	specific	JJ
cord-312119-wzcas4zd	160	12	to	to	IN
cord-312119-wzcas4zd	160	13	F18	F18	NNP
cord-312119-wzcas4zd	160	14	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	160	15	in	in	IN
cord-312119-wzcas4zd	160	16	subcutaneously	subcutaneously	RB
cord-312119-wzcas4zd	160	17	immunized	immunize	VBN
cord-312119-wzcas4zd	160	18	mice	mouse	NNS
cord-312119-wzcas4zd	160	19	.	.	.
cord-312119-wzcas4zd	161	1	More	more	RBR
cord-312119-wzcas4zd	161	2	importantly	importantly	RB
cord-312119-wzcas4zd	161	3	,	,	,
cord-312119-wzcas4zd	161	4	derived	derive	VBN
cord-312119-wzcas4zd	161	5	antibodies	antibody	NNS
cord-312119-wzcas4zd	161	6	showed	show	VBD
cord-312119-wzcas4zd	161	7	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	161	8	activities	activity	NNS
cord-312119-wzcas4zd	161	9	against	against	IN
cord-312119-wzcas4zd	161	10	F18	F18	NNP
cord-312119-wzcas4zd	161	11	fimbria	fimbria	NN
cord-312119-wzcas4zd	161	12	adherence	adherence	NN
cord-312119-wzcas4zd	161	13	to	to	IN
cord-312119-wzcas4zd	161	14	pig	pig	NN
cord-312119-wzcas4zd	161	15	intestine	intestine	NN
cord-312119-wzcas4zd	161	16	cell	cell	NN
cord-312119-wzcas4zd	161	17	line	line	NN
cord-312119-wzcas4zd	161	18	IPEC	IPEC	NNP
cord-312119-wzcas4zd	161	19	-	-	HYPH
cord-312119-wzcas4zd	161	20	J2	J2	NNP
cord-312119-wzcas4zd	161	21	.	.	.
cord-312119-wzcas4zd	162	1	Among	among	IN
cord-312119-wzcas4zd	162	2	seven	seven	CD
cord-312119-wzcas4zd	162	3	FedF	FedF	NNP
cord-312119-wzcas4zd	162	4	epitopes	epitope	NNS
cord-312119-wzcas4zd	162	5	that	that	WDT
cord-312119-wzcas4zd	162	6	induce	induce	VBP
cord-312119-wzcas4zd	162	7	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	162	8	anti	anti	JJ
cord-312119-wzcas4zd	162	9	-	-	JJ
cord-312119-wzcas4zd	162	10	F18	f18	JJ
cord-312119-wzcas4zd	162	11	antibodies	antibody	NNS
cord-312119-wzcas4zd	162	12	,	,	,
cord-312119-wzcas4zd	162	13	epitope	epitope	NN
cord-312119-wzcas4zd	162	14	3	3	CD
cord-312119-wzcas4zd	162	15	and	and	CC
cord-312119-wzcas4zd	162	16	epitope	epitope	NN
cord-312119-wzcas4zd	162	17	7	7	CD
cord-312119-wzcas4zd	162	18	displayed	display	VBD
cord-312119-wzcas4zd	162	19	better	well	RBR
cord-312119-wzcas4zd	162	20	in	in	IN
cord-312119-wzcas4zd	162	21	inducing	induce	VBG
cord-312119-wzcas4zd	162	22	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	162	23	anti	anti	JJ
cord-312119-wzcas4zd	162	24	-	-	JJ
cord-312119-wzcas4zd	162	25	F18	f18	JJ
cord-312119-wzcas4zd	162	26	antibodies	antibody	NNS
cord-312119-wzcas4zd	162	27	,	,	,
cord-312119-wzcas4zd	162	28	suggesting	suggest	VBG
cord-312119-wzcas4zd	162	29	their	-PRON-	PRP$
cord-312119-wzcas4zd	162	30	potential	potential	JJ
cord-312119-wzcas4zd	162	31	application	application	NN
cord-312119-wzcas4zd	162	32	in	in	IN
cord-312119-wzcas4zd	162	33	vaccine	vaccine	NN
cord-312119-wzcas4zd	162	34	development	development	NN
cord-312119-wzcas4zd	162	35	against	against	IN
cord-312119-wzcas4zd	162	36	PWD	PWD	NNP
cord-312119-wzcas4zd	162	37	.	.	.
cord-312119-wzcas4zd	163	1	Authors	author	NNS
cord-312119-wzcas4zd	163	2	declare	declare	VBP
cord-312119-wzcas4zd	163	3	no	no	DT
cord-312119-wzcas4zd	163	4	conflict	conflict	NN
cord-312119-wzcas4zd	163	5	of	of	IN
cord-312119-wzcas4zd	163	6	interests	interest	NNS
cord-312119-wzcas4zd	163	7	from	from	IN
cord-312119-wzcas4zd	163	8	this	this	DT
cord-312119-wzcas4zd	163	9	study	study	NN
cord-312119-wzcas4zd	163	10	.	.	.
cord-312119-wzcas4zd	164	1	Drs	Drs	NNP
cord-312119-wzcas4zd	164	2	.	.	.
cord-312119-wzcas4zd	165	1	Zhang	Zhang	NNP
cord-312119-wzcas4zd	165	2	and	and	CC
cord-312119-wzcas4zd	165	3	Moxley	Moxley	NNP
cord-312119-wzcas4zd	165	4	are	be	VBP
cord-312119-wzcas4zd	165	5	developing	develop	VBG
cord-312119-wzcas4zd	165	6	a	a	DT
cord-312119-wzcas4zd	165	7	broadly	broadly	RB
cord-312119-wzcas4zd	165	8	protective	protective	JJ
cord-312119-wzcas4zd	165	9	vaccine	vaccine	NN
cord-312119-wzcas4zd	165	10	against	against	IN
cord-312119-wzcas4zd	165	11	PWD	PWD	NNP
cord-312119-wzcas4zd	165	12	.	.	.
cord-312119-wzcas4zd	166	1	Presentation	presentation	NN
cord-312119-wzcas4zd	166	2	of	of	IN
cord-312119-wzcas4zd	166	3	postweaning	postweane	VBG
cord-312119-wzcas4zd	166	4	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	166	5	coli	coli	NNS
cord-312119-wzcas4zd	166	6	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	166	7	in	in	IN
cord-312119-wzcas4zd	166	8	southern	southern	JJ
cord-312119-wzcas4zd	166	9	Ontario	Ontario	NNP
cord-312119-wzcas4zd	166	10	,	,	,
cord-312119-wzcas4zd	166	11	prevalence	prevalence	NN
cord-312119-wzcas4zd	166	12	of	of	IN
cord-312119-wzcas4zd	166	13	hemolytic	hemolytic	JJ
cord-312119-wzcas4zd	166	14	E.	E.	NNP
cord-312119-wzcas4zd	166	15	Coli	Coli	NNP
cord-312119-wzcas4zd	166	16	serogroups	serogroup	NNS
cord-312119-wzcas4zd	166	17	involved	involve	VBN
cord-312119-wzcas4zd	166	18	,	,	,
cord-312119-wzcas4zd	166	19	and	and	CC
cord-312119-wzcas4zd	166	20	their	-PRON-	PRP$
cord-312119-wzcas4zd	166	21	antimicrobial	antimicrobial	JJ
cord-312119-wzcas4zd	166	22	resistance	resistance	NN
cord-312119-wzcas4zd	166	23	patterns	pattern	NNS
cord-312119-wzcas4zd	166	24	Pilus	Pilus	NNP
cord-312119-wzcas4zd	166	25	production	production	NN
cord-312119-wzcas4zd	166	26	,	,	,
cord-312119-wzcas4zd	166	27	hemagglutination	hemagglutination	NN
cord-312119-wzcas4zd	166	28	,	,	,
cord-312119-wzcas4zd	166	29	and	and	CC
cord-312119-wzcas4zd	166	30	adhesion	adhesion	NN
cord-312119-wzcas4zd	166	31	by	by	IN
cord-312119-wzcas4zd	166	32	porcine	porcine	JJ
cord-312119-wzcas4zd	166	33	strains	strain	NNS
cord-312119-wzcas4zd	166	34	of	of	IN
cord-312119-wzcas4zd	166	35	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	166	36	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	166	37	coli	coli	NNS
cord-312119-wzcas4zd	166	38	lacking	lack	VBG
cord-312119-wzcas4zd	166	39	K88	K88	NNP
cord-312119-wzcas4zd	166	40	,	,	,
cord-312119-wzcas4zd	166	41	K99	K99	NNP
cord-312119-wzcas4zd	166	42	,	,	,
cord-312119-wzcas4zd	166	43	and	and	CC
cord-312119-wzcas4zd	166	44	987P	987p	CD
cord-312119-wzcas4zd	166	45	antigens	antigen	NNS
cord-312119-wzcas4zd	166	46	Exploring	explore	VBG
cord-312119-wzcas4zd	166	47	the	the	DT
cord-312119-wzcas4zd	166	48	extremes	extreme	NNS
cord-312119-wzcas4zd	166	49	of	of	IN
cord-312119-wzcas4zd	166	50	sequence	sequence	NN
cord-312119-wzcas4zd	166	51	/	/	SYM
cord-312119-wzcas4zd	166	52	structure	structure	NN
cord-312119-wzcas4zd	166	53	space	space	NN
cord-312119-wzcas4zd	166	54	with	with	IN
cord-312119-wzcas4zd	166	55	ensemble	ensemble	NN
cord-312119-wzcas4zd	166	56	fold	fold	NN
cord-312119-wzcas4zd	166	57	recognition	recognition	NN
cord-312119-wzcas4zd	166	58	in	in	IN
cord-312119-wzcas4zd	166	59	the	the	DT
cord-312119-wzcas4zd	166	60	program	program	NN
cord-312119-wzcas4zd	166	61	Phyre	Phyre	NNP
cord-312119-wzcas4zd	166	62	Relative	Relative	NNP
cord-312119-wzcas4zd	166	63	importance	importance	NN
cord-312119-wzcas4zd	166	64	of	of	IN
cord-312119-wzcas4zd	166	65	heat	heat	NN
cord-312119-wzcas4zd	166	66	-	-	HYPH
cord-312119-wzcas4zd	166	67	labile	labile	JJ
cord-312119-wzcas4zd	166	68	enterotoxin	enterotoxin	NN
cord-312119-wzcas4zd	166	69	in	in	IN
cord-312119-wzcas4zd	166	70	the	the	DT
cord-312119-wzcas4zd	166	71	causation	causation	NN
cord-312119-wzcas4zd	166	72	of	of	IN
cord-312119-wzcas4zd	166	73	severe	severe	JJ
cord-312119-wzcas4zd	166	74	diarrheal	diarrheal	JJ
cord-312119-wzcas4zd	166	75	disease	disease	NN
cord-312119-wzcas4zd	166	76	in	in	IN
cord-312119-wzcas4zd	166	77	the	the	DT
cord-312119-wzcas4zd	166	78	gnotobiotic	gnotobiotic	JJ
cord-312119-wzcas4zd	166	79	piglet	piglet	NN
cord-312119-wzcas4zd	166	80	model	model	NN
cord-312119-wzcas4zd	166	81	by	by	IN
cord-312119-wzcas4zd	166	82	a	a	DT
cord-312119-wzcas4zd	166	83	strain	strain	NN
cord-312119-wzcas4zd	166	84	of	of	IN
cord-312119-wzcas4zd	166	85	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	166	86	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	166	87	coli	coli	NNS
cord-312119-wzcas4zd	166	88	that	that	WDT
cord-312119-wzcas4zd	166	89	produces	produce	VBZ
cord-312119-wzcas4zd	166	90	multiple	multiple	JJ
cord-312119-wzcas4zd	166	91	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	166	92	Active	active	JJ
cord-312119-wzcas4zd	166	93	oral	oral	JJ
cord-312119-wzcas4zd	166	94	immunization	immunization	NN
cord-312119-wzcas4zd	166	95	of	of	IN
cord-312119-wzcas4zd	166	96	suckling	suckle	VBG
cord-312119-wzcas4zd	166	97	piglets	piglet	NNS
cord-312119-wzcas4zd	166	98	to	to	TO
cord-312119-wzcas4zd	166	99	prevent	prevent	VB
cord-312119-wzcas4zd	166	100	colonization	colonization	NN
cord-312119-wzcas4zd	166	101	after	after	IN
cord-312119-wzcas4zd	166	102	weaning	wean	VBG
cord-312119-wzcas4zd	166	103	by	by	IN
cord-312119-wzcas4zd	166	104	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	166	105	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	166	106	coli	coli	NNS
cord-312119-wzcas4zd	166	107	with	with	IN
cord-312119-wzcas4zd	166	108	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	166	109	F18	F18	NNP
cord-312119-wzcas4zd	166	110	Parenteral	Parenteral	NNP
cord-312119-wzcas4zd	166	111	vaccination	vaccination	NN
cord-312119-wzcas4zd	166	112	of	of	IN
cord-312119-wzcas4zd	166	113	mice	mouse	NNS
cord-312119-wzcas4zd	166	114	and	and	CC
cord-312119-wzcas4zd	166	115	piglets	piglet	NNS
cord-312119-wzcas4zd	166	116	with	with	IN
cord-312119-wzcas4zd	166	117	F4	F4	NNP
cord-312119-wzcas4zd	166	118	+	+	CC
cord-312119-wzcas4zd	166	119	Escherichia	escherichia	NN
cord-312119-wzcas4zd	166	120	coli	coli	NNS
cord-312119-wzcas4zd	166	121	suppresses	suppress	VBZ
cord-312119-wzcas4zd	166	122	the	the	DT
cord-312119-wzcas4zd	166	123	enteric	enteric	JJ
cord-312119-wzcas4zd	166	124	anti	anti	JJ
cord-312119-wzcas4zd	166	125	-	-	JJ
cord-312119-wzcas4zd	166	126	F4	f4	JJ
cord-312119-wzcas4zd	166	127	response	response	NN
cord-312119-wzcas4zd	166	128	upon	upon	IN
cord-312119-wzcas4zd	166	129	oral	oral	JJ
cord-312119-wzcas4zd	166	130	infection	infection	NN
cord-312119-wzcas4zd	167	1	The	the	DT
cord-312119-wzcas4zd	167	2	European	european	JJ
cord-312119-wzcas4zd	167	3	ban	ban	NN
cord-312119-wzcas4zd	167	4	on	on	IN
cord-312119-wzcas4zd	167	5	growth	growth	NN
cord-312119-wzcas4zd	167	6	-	-	HYPH
cord-312119-wzcas4zd	167	7	promoting	promote	VBG
cord-312119-wzcas4zd	167	8	antibiotics	antibiotic	NNS
cord-312119-wzcas4zd	167	9	and	and	CC
cord-312119-wzcas4zd	167	10	emerging	emerge	VBG
cord-312119-wzcas4zd	167	11	consequences	consequence	NNS
cord-312119-wzcas4zd	167	12	for	for	IN
cord-312119-wzcas4zd	167	13	human	human	JJ
cord-312119-wzcas4zd	167	14	and	and	CC
cord-312119-wzcas4zd	167	15	animal	animal	NN
cord-312119-wzcas4zd	167	16	health	health	NN
cord-312119-wzcas4zd	167	17	Genetic	genetic	JJ
cord-312119-wzcas4zd	167	18	characterization	characterization	NN
cord-312119-wzcas4zd	167	19	and	and	CC
cord-312119-wzcas4zd	167	20	virulence	virulence	NN
cord-312119-wzcas4zd	167	21	of	of	IN
cord-312119-wzcas4zd	167	22	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	167	23	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	167	24	coli	coli	VBZ
cord-312119-wzcas4zd	167	25	mutants	mutant	NNS
cord-312119-wzcas4zd	167	26	which	which	WDT
cord-312119-wzcas4zd	167	27	have	have	VBP
cord-312119-wzcas4zd	167	28	lost	lose	VBN
cord-312119-wzcas4zd	167	29	virulence	virulence	NN
cord-312119-wzcas4zd	167	30	genes	gene	NNS
cord-312119-wzcas4zd	167	31	in	in	IN
cord-312119-wzcas4zd	167	32	vivo	vivo	NN
cord-312119-wzcas4zd	168	1	The	the	DT
cord-312119-wzcas4zd	168	2	age	age	NN
cord-312119-wzcas4zd	168	3	-	-	HYPH
cord-312119-wzcas4zd	168	4	dependent	dependent	JJ
cord-312119-wzcas4zd	168	5	expression	expression	NN
cord-312119-wzcas4zd	168	6	of	of	IN
cord-312119-wzcas4zd	168	7	the	the	DT
cord-312119-wzcas4zd	168	8	F18	F18	NNP
cord-312119-wzcas4zd	168	9	+	+	CC
cord-312119-wzcas4zd	168	10	E.	E.	NNP
cord-312119-wzcas4zd	168	11	coli	coli	VBZ
cord-312119-wzcas4zd	168	12	receptor	receptor	NN
cord-312119-wzcas4zd	168	13	on	on	IN
cord-312119-wzcas4zd	168	14	porcine	porcine	JJ
cord-312119-wzcas4zd	168	15	gut	gut	NN
cord-312119-wzcas4zd	168	16	epithelial	epithelial	JJ
cord-312119-wzcas4zd	168	17	cells	cell	NNS
cord-312119-wzcas4zd	168	18	is	be	VBZ
cord-312119-wzcas4zd	168	19	positively	positively	RB
cord-312119-wzcas4zd	168	20	correlated	correlate	VBN
cord-312119-wzcas4zd	168	21	with	with	IN
cord-312119-wzcas4zd	168	22	the	the	DT
cord-312119-wzcas4zd	168	23	presence	presence	NN
cord-312119-wzcas4zd	168	24	of	of	IN
cord-312119-wzcas4zd	168	25	histo	histo	JJ
cord-312119-wzcas4zd	168	26	-	-	HYPH
cord-312119-wzcas4zd	168	27	blood	blood	NN
cord-312119-wzcas4zd	168	28	group	group	NN
cord-312119-wzcas4zd	168	29	antigens	antigen	NNS
cord-312119-wzcas4zd	168	30	Differences	difference	NNS
cord-312119-wzcas4zd	168	31	in	in	IN
cord-312119-wzcas4zd	168	32	antibiotic	antibiotic	JJ
cord-312119-wzcas4zd	168	33	resistance	resistance	NN
cord-312119-wzcas4zd	168	34	in	in	IN
cord-312119-wzcas4zd	168	35	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	168	36	coli	coli	NNS
cord-312119-wzcas4zd	168	37	,	,	,
cord-312119-wzcas4zd	168	38	isolated	isolate	VBN
cord-312119-wzcas4zd	168	39	from	from	IN
cord-312119-wzcas4zd	168	40	East	east	JJ
cord-312119-wzcas4zd	168	41	-	-	HYPH
cord-312119-wzcas4zd	168	42	European	european	JJ
cord-312119-wzcas4zd	168	43	swine	swine	NN
cord-312119-wzcas4zd	168	44	herds	herd	NNS
cord-312119-wzcas4zd	168	45	with	with	IN
cord-312119-wzcas4zd	168	46	or	or	CC
cord-312119-wzcas4zd	168	47	without	without	IN
cord-312119-wzcas4zd	168	48	prophylactic	prophylactic	JJ
cord-312119-wzcas4zd	168	49	use	use	NN
cord-312119-wzcas4zd	168	50	of	of	IN
cord-312119-wzcas4zd	168	51	antibiotics	antibiotic	NNS
cord-312119-wzcas4zd	168	52	MEFA	MEFA	NNP
cord-312119-wzcas4zd	169	1	(	(	-LRB-
cord-312119-wzcas4zd	169	2	multiepitope	multiepitope	NNP
cord-312119-wzcas4zd	169	3	fusion	fusion	NN
cord-312119-wzcas4zd	169	4	antigen)-Novel	antigen)-Novel	HYPH
cord-312119-wzcas4zd	169	5	technology	technology	NN
cord-312119-wzcas4zd	169	6	for	for	IN
cord-312119-wzcas4zd	169	7	structural	structural	JJ
cord-312119-wzcas4zd	169	8	vaccinology	vaccinology	NN
cord-312119-wzcas4zd	169	9	,	,	,
cord-312119-wzcas4zd	169	10	proof	proof	NN
cord-312119-wzcas4zd	169	11	from	from	IN
cord-312119-wzcas4zd	169	12	computational	computational	JJ
cord-312119-wzcas4zd	169	13	and	and	CC
cord-312119-wzcas4zd	169	14	empirical	empirical	JJ
cord-312119-wzcas4zd	169	15	immunogenicity	immunogenicity	NN
cord-312119-wzcas4zd	169	16	characterization	characterization	NN
cord-312119-wzcas4zd	169	17	of	of	IN
cord-312119-wzcas4zd	169	18	an	an	DT
cord-312119-wzcas4zd	169	19	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	169	20	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	169	21	coli	coli	NNS
cord-312119-wzcas4zd	169	22	(	(	-LRB-
cord-312119-wzcas4zd	169	23	ETEC	ETEC	NNP
cord-312119-wzcas4zd	169	24	)	)	-RRB-
cord-312119-wzcas4zd	169	25	adhesin	adhesin	NNP
cord-312119-wzcas4zd	169	26	MEFA	MEFA	NNP
cord-312119-wzcas4zd	169	27	Genetic	Genetic	NNP
cord-312119-wzcas4zd	169	28	fusion	fusion	NN
cord-312119-wzcas4zd	169	29	protein	protein	NN
cord-312119-wzcas4zd	169	30	3xSTa	3xsta	NN
cord-312119-wzcas4zd	169	31	-	-	HYPH
cord-312119-wzcas4zd	169	32	ovalbumin	ovalbumin	NNP
cord-312119-wzcas4zd	169	33	is	be	VBZ
cord-312119-wzcas4zd	169	34	an	an	DT
cord-312119-wzcas4zd	169	35	effective	effective	JJ
cord-312119-wzcas4zd	169	36	coating	coating	NN
cord-312119-wzcas4zd	169	37	antigen	antigen	NN
cord-312119-wzcas4zd	169	38	in	in	IN
cord-312119-wzcas4zd	169	39	ELISA	ELISA	NNP
cord-312119-wzcas4zd	169	40	to	to	TO
cord-312119-wzcas4zd	169	41	titrate	titrate	VB
cord-312119-wzcas4zd	169	42	anti	anti	JJ
cord-312119-wzcas4zd	169	43	-	-	JJ
cord-312119-wzcas4zd	169	44	STa	sta	JJ
cord-312119-wzcas4zd	169	45	antibodies	antibody	NNS
cord-312119-wzcas4zd	170	1	Comparison	comparison	NN
cord-312119-wzcas4zd	170	2	of	of	IN
cord-312119-wzcas4zd	170	3	the	the	DT
cord-312119-wzcas4zd	170	4	contributions	contribution	NNS
cord-312119-wzcas4zd	170	5	of	of	IN
cord-312119-wzcas4zd	170	6	heat	heat	NN
cord-312119-wzcas4zd	170	7	-	-	HYPH
cord-312119-wzcas4zd	170	8	labile	labile	JJ
cord-312119-wzcas4zd	170	9	enterotoxin	enterotoxin	JJ
cord-312119-wzcas4zd	170	10	and	and	CC
cord-312119-wzcas4zd	170	11	heatstable	heatstable	JJ
cord-312119-wzcas4zd	170	12	enterotoxin	enterotoxin	NNP
cord-312119-wzcas4zd	170	13	b	b	NNP
cord-312119-wzcas4zd	170	14	to	to	IN
cord-312119-wzcas4zd	170	15	the	the	DT
cord-312119-wzcas4zd	170	16	virulence	virulence	NN
cord-312119-wzcas4zd	170	17	of	of	IN
cord-312119-wzcas4zd	170	18	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	170	19	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	170	20	coli	coli	NNS
cord-312119-wzcas4zd	170	21	in	in	IN
cord-312119-wzcas4zd	170	22	F4ac	f4ac	JJ
cord-312119-wzcas4zd	170	23	receptor	receptor	NN
cord-312119-wzcas4zd	170	24	-	-	HYPH
cord-312119-wzcas4zd	170	25	positive	positive	JJ
cord-312119-wzcas4zd	170	26	young	young	JJ
cord-312119-wzcas4zd	170	27	pigs	pig	NNS
cord-312119-wzcas4zd	170	28	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	170	29	coli	coli	NNS
cord-312119-wzcas4zd	170	30	in	in	IN
cord-312119-wzcas4zd	170	31	postweaning	postweane	VBG
cord-312119-wzcas4zd	170	32	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	170	33	in	in	IN
cord-312119-wzcas4zd	170	34	pigs	pig	NNS
cord-312119-wzcas4zd	170	35	:	:	:
cord-312119-wzcas4zd	170	36	an	an	DT
cord-312119-wzcas4zd	170	37	update	update	NN
cord-312119-wzcas4zd	170	38	on	on	IN
cord-312119-wzcas4zd	170	39	bacterial	bacterial	JJ
cord-312119-wzcas4zd	170	40	types	type	NNS
cord-312119-wzcas4zd	170	41	,	,	,
cord-312119-wzcas4zd	170	42	pathogenesis	pathogenesis	NN
cord-312119-wzcas4zd	170	43	,	,	,
cord-312119-wzcas4zd	170	44	and	and	CC
cord-312119-wzcas4zd	170	45	prevention	prevention	NN
cord-312119-wzcas4zd	170	46	strategies	strategy	NNS
cord-312119-wzcas4zd	170	47	Enterotoxigenic	Enterotoxigenic	NNP
cord-312119-wzcas4zd	170	48	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	170	49	coli	coli	VBZ
cord-312119-wzcas4zd	170	50	infection	infection	NN
cord-312119-wzcas4zd	170	51	in	in	IN
cord-312119-wzcas4zd	170	52	pigs	pig	NNS
cord-312119-wzcas4zd	170	53	and	and	CC
cord-312119-wzcas4zd	170	54	its	-PRON-	PRP$
cord-312119-wzcas4zd	170	55	diagnosis	diagnosis	NN
cord-312119-wzcas4zd	170	56	Evaluation	evaluation	NN
cord-312119-wzcas4zd	170	57	of	of	IN
cord-312119-wzcas4zd	170	58	a	a	DT
cord-312119-wzcas4zd	170	59	live	live	JJ
cord-312119-wzcas4zd	170	60	avirulent	avirulent	NN
cord-312119-wzcas4zd	170	61	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	170	62	coli	coli	VBZ
cord-312119-wzcas4zd	170	63	vaccine	vaccine	NN
cord-312119-wzcas4zd	170	64	for	for	IN
cord-312119-wzcas4zd	170	65	K88	K88	NNP
cord-312119-wzcas4zd	171	1	+	+	CC
cord-312119-wzcas4zd	171	2	,	,	,
cord-312119-wzcas4zd	171	3	LT+	LT+	NNP
cord-312119-wzcas4zd	171	4	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	171	5	colibacillosis	colibacillosis	NN
cord-312119-wzcas4zd	171	6	in	in	IN
cord-312119-wzcas4zd	171	7	weaned	wean	VBN
cord-312119-wzcas4zd	171	8	pigs	pig	NNS
cord-312119-wzcas4zd	171	9	Prevalence	prevalence	NN
cord-312119-wzcas4zd	171	10	of	of	IN
cord-312119-wzcas4zd	171	11	serogroups	serogroup	NNS
cord-312119-wzcas4zd	171	12	and	and	CC
cord-312119-wzcas4zd	171	13	virulence	virulence	NN
cord-312119-wzcas4zd	171	14	genes	gene	NNS
cord-312119-wzcas4zd	171	15	in	in	IN
cord-312119-wzcas4zd	171	16	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	171	17	coli	coli	NNS
cord-312119-wzcas4zd	171	18	associated	associate	VBN
cord-312119-wzcas4zd	171	19	with	with	IN
cord-312119-wzcas4zd	171	20	postweaning	postweane	VBG
cord-312119-wzcas4zd	171	21	diarrhoea	diarrhoea	NN
cord-312119-wzcas4zd	171	22	and	and	CC
cord-312119-wzcas4zd	171	23	edema	edema	NN
cord-312119-wzcas4zd	171	24	disease	disease	NN
cord-312119-wzcas4zd	171	25	in	in	IN
cord-312119-wzcas4zd	171	26	pigs	pig	NNS
cord-312119-wzcas4zd	171	27	and	and	CC
cord-312119-wzcas4zd	171	28	a	a	DT
cord-312119-wzcas4zd	171	29	comparison	comparison	NN
cord-312119-wzcas4zd	171	30	of	of	IN
cord-312119-wzcas4zd	171	31	diagnostic	diagnostic	JJ
cord-312119-wzcas4zd	171	32	approaches	approach	NNS
cord-312119-wzcas4zd	171	33	Inoculation	Inoculation	NNP
cord-312119-wzcas4zd	171	34	of	of	IN
cord-312119-wzcas4zd	171	35	nonpathogneic	nonpathogneic	NNS
cord-312119-wzcas4zd	171	36	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	171	37	coli	coli	NNS
cord-312119-wzcas4zd	171	38	to	to	TO
cord-312119-wzcas4zd	171	39	control	control	VB
cord-312119-wzcas4zd	171	40	disease	disease	NN
cord-312119-wzcas4zd	171	41	and	and	CC
cord-312119-wzcas4zd	171	42	reduce	reduce	VB
cord-312119-wzcas4zd	171	43	antibiotic	antibiotic	JJ
cord-312119-wzcas4zd	171	44	usage	usage	NN
cord-312119-wzcas4zd	171	45	Host	host	NN
cord-312119-wzcas4zd	171	46	-	-	HYPH
cord-312119-wzcas4zd	171	47	specific	specific	JJ
cord-312119-wzcas4zd	171	48	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	171	49	adhesins	adhesin	NNS
cord-312119-wzcas4zd	171	50	of	of	IN
cord-312119-wzcas4zd	171	51	noninvasive	noninvasive	JJ
cord-312119-wzcas4zd	171	52	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	171	53	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	171	54	coli	coli	NNS
cord-312119-wzcas4zd	171	55	strains	strain	NNS
cord-312119-wzcas4zd	171	56	Efficacy	Efficacy	NNP
cord-312119-wzcas4zd	171	57	of	of	IN
cord-312119-wzcas4zd	171	58	vaccines	vaccine	NNS
cord-312119-wzcas4zd	171	59	against	against	IN
cord-312119-wzcas4zd	171	60	bacterial	bacterial	JJ
cord-312119-wzcas4zd	171	61	diseases	disease	NNS
cord-312119-wzcas4zd	171	62	in	in	IN
cord-312119-wzcas4zd	171	63	swine	swine	NN
cord-312119-wzcas4zd	171	64	:	:	:
cord-312119-wzcas4zd	171	65	what	what	WP
cord-312119-wzcas4zd	171	66	can	can	MD
cord-312119-wzcas4zd	171	67	we	-PRON-	PRP
cord-312119-wzcas4zd	171	68	expect	expect	VB
cord-312119-wzcas4zd	171	69	?	?	.
cord-312119-wzcas4zd	172	1	Postweaning	Postweaning	NNP
cord-312119-wzcas4zd	172	2	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	172	3	coli	coli	NNS
cord-312119-wzcas4zd	172	4	diarrhoea	diarrhoea	NN
cord-312119-wzcas4zd	172	5	in	in	IN
cord-312119-wzcas4zd	172	6	pigs	pig	NNS
cord-312119-wzcas4zd	172	7	Significance	significance	NN
cord-312119-wzcas4zd	172	8	of	of	IN
cord-312119-wzcas4zd	172	9	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	172	10	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	172	11	coli	coli	NNS
cord-312119-wzcas4zd	172	12	(	(	-LRB-
cord-312119-wzcas4zd	172	13	ETEC	ETEC	NNP
cord-312119-wzcas4zd	172	14	)	)	-RRB-
cord-312119-wzcas4zd	172	15	HeatLabile	HeatLabile	NNP
cord-312119-wzcas4zd	172	16	toxin	toxin	NN
cord-312119-wzcas4zd	172	17	(	(	-LRB-
cord-312119-wzcas4zd	172	18	LT	LT	NNP
cord-312119-wzcas4zd	172	19	)	)	-RRB-
cord-312119-wzcas4zd	172	20	enzymatic	enzymatic	JJ
cord-312119-wzcas4zd	172	21	subunit	subunit	NN
cord-312119-wzcas4zd	172	22	epitopes	epitope	NNS
cord-312119-wzcas4zd	172	23	in	in	IN
cord-312119-wzcas4zd	172	24	LT	LT	NNP
cord-312119-wzcas4zd	172	25	enterotoxicity	enterotoxicity	NN
cord-312119-wzcas4zd	172	26	and	and	CC
cord-312119-wzcas4zd	172	27	immunogenicity	immunogenicity	JJ
cord-312119-wzcas4zd	172	28	Characterization	characterization	NN
cord-312119-wzcas4zd	172	29	of	of	IN
cord-312119-wzcas4zd	172	30	F18	F18	NNP
cord-312119-wzcas4zd	172	31	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	172	32	genes	gene	NNS
cord-312119-wzcas4zd	172	33	fedE	fedE	''
cord-312119-wzcas4zd	172	34	and	and	CC
cord-312119-wzcas4zd	172	35	fedF	fedf	NN
cord-312119-wzcas4zd	172	36	involved	involve	VBN
cord-312119-wzcas4zd	172	37	in	in	IN
cord-312119-wzcas4zd	172	38	adhesion	adhesion	NN
cord-312119-wzcas4zd	172	39	and	and	CC
cord-312119-wzcas4zd	172	40	length	length	NN
cord-312119-wzcas4zd	172	41	of	of	IN
cord-312119-wzcas4zd	172	42	enterotoxemic	enterotoxemic	NNP
cord-312119-wzcas4zd	172	43	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	172	44	coli	coli	NNS
cord-312119-wzcas4zd	172	45	strain	strain	NN
cord-312119-wzcas4zd	172	46	107/86	107/86	CD
cord-312119-wzcas4zd	172	47	Fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	172	48	colonisation	colonisation	NN
cord-312119-wzcas4zd	172	49	factors	factor	NNS
cord-312119-wzcas4zd	172	50	F18ab	F18ab	NNP
cord-312119-wzcas4zd	172	51	and	and	CC
cord-312119-wzcas4zd	172	52	F18ac	F18ac	NNP
cord-312119-wzcas4zd	172	53	of	of	IN
cord-312119-wzcas4zd	172	54	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	172	55	coli	coli	NNS
cord-312119-wzcas4zd	172	56	isolated	isolate	VBN
cord-312119-wzcas4zd	172	57	from	from	IN
cord-312119-wzcas4zd	172	58	pigs	pig	NNS
cord-312119-wzcas4zd	172	59	with	with	IN
cord-312119-wzcas4zd	172	60	postweaning	postweane	VBG
cord-312119-wzcas4zd	172	61	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	172	62	and	and	CC
cord-312119-wzcas4zd	172	63	edema	edema	NN
cord-312119-wzcas4zd	172	64	disease	disease	NNP
cord-312119-wzcas4zd	172	65	Protein	Protein	NNP
cord-312119-wzcas4zd	172	66	structure	structure	NN
cord-312119-wzcas4zd	172	67	prediction	prediction	NN
cord-312119-wzcas4zd	172	68	on	on	IN
cord-312119-wzcas4zd	172	69	the	the	DT
cord-312119-wzcas4zd	172	70	Web	web	NN
cord-312119-wzcas4zd	172	71	:	:	:
cord-312119-wzcas4zd	172	72	a	a	DT
cord-312119-wzcas4zd	172	73	case	case	NN
cord-312119-wzcas4zd	172	74	study	study	NN
cord-312119-wzcas4zd	172	75	using	use	VBG
cord-312119-wzcas4zd	172	76	the	the	DT
cord-312119-wzcas4zd	172	77	Phyre	Phyre	NNP
cord-312119-wzcas4zd	172	78	server	server	NN
cord-312119-wzcas4zd	172	79	Improved	improve	VBN
cord-312119-wzcas4zd	172	80	method	method	NN
cord-312119-wzcas4zd	172	81	for	for	IN
cord-312119-wzcas4zd	172	82	predicting	predict	VBG
cord-312119-wzcas4zd	172	83	linear	linear	NNP
cord-312119-wzcas4zd	172	84	B	b	NN
cord-312119-wzcas4zd	172	85	-	-	HYPH
cord-312119-wzcas4zd	172	86	cell	cell	NN
cord-312119-wzcas4zd	172	87	epitopes	epitope	NNS
cord-312119-wzcas4zd	173	1	Characterization	characterization	NN
cord-312119-wzcas4zd	173	2	of	of	IN
cord-312119-wzcas4zd	173	3	the	the	DT
cord-312119-wzcas4zd	173	4	gene	gene	NN
cord-312119-wzcas4zd	173	5	encoding	encode	VBG
cord-312119-wzcas4zd	173	6	heat	heat	NN
cord-312119-wzcas4zd	173	7	-	-	HYPH
cord-312119-wzcas4zd	173	8	stable	stable	JJ
cord-312119-wzcas4zd	173	9	toxin	toxin	NN
cord-312119-wzcas4zd	173	10	II	II	NNP
cord-312119-wzcas4zd	173	11	and	and	CC
cord-312119-wzcas4zd	173	12	preliminary	preliminary	JJ
cord-312119-wzcas4zd	173	13	molecular	molecular	JJ
cord-312119-wzcas4zd	173	14	epidemiological	epidemiological	JJ
cord-312119-wzcas4zd	173	15	studies	study	NNS
cord-312119-wzcas4zd	173	16	of	of	IN
cord-312119-wzcas4zd	173	17	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	173	18	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	173	19	coli	coli	VBZ
cord-312119-wzcas4zd	173	20	heat	heat	NN
cord-312119-wzcas4zd	173	21	-	-	HYPH
cord-312119-wzcas4zd	173	22	stable	stable	JJ
cord-312119-wzcas4zd	173	23	toxin	toxin	NN
cord-312119-wzcas4zd	173	24	II	ii	CD
cord-312119-wzcas4zd	173	25	producers	producer	NNS
cord-312119-wzcas4zd	173	26	Identifying	identify	VBG
cord-312119-wzcas4zd	173	27	immuno	immuno	JJ
cord-312119-wzcas4zd	173	28	-	-	JJ
cord-312119-wzcas4zd	173	29	dominant	dominant	JJ
cord-312119-wzcas4zd	173	30	and	and	CC
cord-312119-wzcas4zd	173	31	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	173	32	epitopes	epitope	NNS
cord-312119-wzcas4zd	173	33	from	from	IN
cord-312119-wzcas4zd	173	34	K88	K88	NNP
cord-312119-wzcas4zd	173	35	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	173	36	of	of	IN
cord-312119-wzcas4zd	173	37	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	173	38	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	173	39	coli	coli	NNS
cord-312119-wzcas4zd	173	40	(	(	-LRB-
cord-312119-wzcas4zd	173	41	ETEC	ETEC	NNP
cord-312119-wzcas4zd	173	42	)	)	-RRB-
cord-312119-wzcas4zd	173	43	ETEC	etec	JJ
cord-312119-wzcas4zd	173	44	vaccination	vaccination	NN
cord-312119-wzcas4zd	173	45	in	in	IN
cord-312119-wzcas4zd	173	46	pigs	pig	NNS
cord-312119-wzcas4zd	173	47	Vaccines	vaccine	NNS
cord-312119-wzcas4zd	173	48	and	and	CC
cord-312119-wzcas4zd	173	49	antibiotic	antibiotic	JJ
cord-312119-wzcas4zd	173	50	resistance	resistance	NN
cord-312119-wzcas4zd	173	51	Prevalence	prevalence	NN
cord-312119-wzcas4zd	173	52	of	of	IN
cord-312119-wzcas4zd	173	53	pilus	pilus	NN
cord-312119-wzcas4zd	173	54	antigens	antigen	NNS
cord-312119-wzcas4zd	173	55	,	,	,
cord-312119-wzcas4zd	173	56	enterotoxin	enterotoxin	JJ
cord-312119-wzcas4zd	173	57	types	type	NNS
cord-312119-wzcas4zd	173	58	,	,	,
cord-312119-wzcas4zd	173	59	and	and	CC
cord-312119-wzcas4zd	173	60	enteropathogenicity	enteropathogenicity	NN
cord-312119-wzcas4zd	173	61	among	among	IN
cord-312119-wzcas4zd	173	62	K88-negative	K88-negative	NNP
cord-312119-wzcas4zd	173	63	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	173	64	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	173	65	coli	coli	NNS
cord-312119-wzcas4zd	173	66	from	from	IN
cord-312119-wzcas4zd	173	67	neonatal	neonatal	JJ
cord-312119-wzcas4zd	173	68	pigs	pig	NNS
cord-312119-wzcas4zd	173	69	Cloning	clone	VBG
cord-312119-wzcas4zd	173	70	of	of	IN
cord-312119-wzcas4zd	173	71	chromosomal	chromosomal	JJ
cord-312119-wzcas4zd	173	72	DNA	dna	NN
cord-312119-wzcas4zd	173	73	encoding	encode	VBG
cord-312119-wzcas4zd	173	74	the	the	DT
cord-312119-wzcas4zd	173	75	F41	F41	NNP
cord-312119-wzcas4zd	173	76	adhesin	adhesin	NN
cord-312119-wzcas4zd	173	77	of	of	IN
cord-312119-wzcas4zd	173	78	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	173	79	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	173	80	coli	coli	NNS
cord-312119-wzcas4zd	173	81	and	and	CC
cord-312119-wzcas4zd	173	82	genetic	genetic	JJ
cord-312119-wzcas4zd	173	83	homology	homology	NN
cord-312119-wzcas4zd	173	84	between	between	IN
cord-312119-wzcas4zd	173	85	adhesins	adhesin	NNS
cord-312119-wzcas4zd	173	86	F41	F41	NNP
cord-312119-wzcas4zd	173	87	and	and	CC
cord-312119-wzcas4zd	173	88	K88	K88	NNP
cord-312119-wzcas4zd	173	89	Enterotoxigenic	Enterotoxigenic	NNP
cord-312119-wzcas4zd	173	90	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	173	91	coli	coli	NNS
cord-312119-wzcas4zd	173	92	(	(	-LRB-
cord-312119-wzcas4zd	173	93	ETEC	ETEC	NNP
cord-312119-wzcas4zd	173	94	)	)	-RRB-
cord-312119-wzcas4zd	173	95	in	in	IN
cord-312119-wzcas4zd	173	96	farm	farm	NN
cord-312119-wzcas4zd	173	97	animals	animal	NNS
cord-312119-wzcas4zd	173	98	Colonization	colonization	NN
cord-312119-wzcas4zd	173	99	of	of	IN
cord-312119-wzcas4zd	173	100	porcine	porcine	JJ
cord-312119-wzcas4zd	173	101	intestine	intestine	NN
cord-312119-wzcas4zd	173	102	by	by	IN
cord-312119-wzcas4zd	173	103	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	173	104	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	173	105	coli	coli	NNS
cord-312119-wzcas4zd	173	106	:	:	:
cord-312119-wzcas4zd	173	107	selection	selection	NN
cord-312119-wzcas4zd	173	108	of	of	IN
cord-312119-wzcas4zd	173	109	piliated	piliated	JJ
cord-312119-wzcas4zd	173	110	forms	form	NNS
cord-312119-wzcas4zd	173	111	in	in	IN
cord-312119-wzcas4zd	173	112	vivo	vivo	NN
cord-312119-wzcas4zd	173	113	,	,	,
cord-312119-wzcas4zd	173	114	adhesion	adhesion	NN
cord-312119-wzcas4zd	173	115	of	of	IN
cord-312119-wzcas4zd	173	116	piliated	piliated	JJ
cord-312119-wzcas4zd	173	117	forms	form	NNS
cord-312119-wzcas4zd	173	118	to	to	IN
cord-312119-wzcas4zd	173	119	epithelial	epithelial	JJ
cord-312119-wzcas4zd	173	120	cells	cell	NNS
cord-312119-wzcas4zd	173	121	in	in	IN
cord-312119-wzcas4zd	173	122	vitro	vitro	FW
cord-312119-wzcas4zd	173	123	,	,	,
cord-312119-wzcas4zd	173	124	and	and	CC
cord-312119-wzcas4zd	173	125	incidence	incidence	NN
cord-312119-wzcas4zd	173	126	of	of	IN
cord-312119-wzcas4zd	173	127	a	a	DT
cord-312119-wzcas4zd	173	128	pilus	pilus	NN
cord-312119-wzcas4zd	173	129	antigen	antigen	NN
cord-312119-wzcas4zd	173	130	among	among	IN
cord-312119-wzcas4zd	173	131	porcine	porcine	JJ
cord-312119-wzcas4zd	173	132	enteropathogenic	enteropathogenic	JJ
cord-312119-wzcas4zd	173	133	E.	E.	NNP
cord-312119-wzcas4zd	173	134	Coli	Coli	NNP
cord-312119-wzcas4zd	173	135	Biological	biological	JJ
cord-312119-wzcas4zd	173	136	relationship	relationship	NN
cord-312119-wzcas4zd	173	137	between	between	IN
cord-312119-wzcas4zd	173	138	F18ab	F18ab	NNP
cord-312119-wzcas4zd	173	139	and	and	CC
cord-312119-wzcas4zd	173	140	F18ac	F18ac	NNP
cord-312119-wzcas4zd	173	141	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	173	142	of	of	IN
cord-312119-wzcas4zd	173	143	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	173	144	and	and	CC
cord-312119-wzcas4zd	173	145	verotoxigenic	verotoxigenic	NNP
cord-312119-wzcas4zd	173	146	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	173	147	coli	coli	NNS
cord-312119-wzcas4zd	173	148	from	from	IN
cord-312119-wzcas4zd	173	149	weaned	wean	VBN
cord-312119-wzcas4zd	173	150	pigs	pig	NNS
cord-312119-wzcas4zd	173	151	with	with	IN
cord-312119-wzcas4zd	173	152	oedema	oedema	NN
cord-312119-wzcas4zd	173	153	disease	disease	NN
cord-312119-wzcas4zd	173	154	or	or	CC
cord-312119-wzcas4zd	173	155	diarrhoea	diarrhoea	NN
cord-312119-wzcas4zd	173	156	Virulence	Virulence	NNP
cord-312119-wzcas4zd	173	157	factors	factor	NNS
cord-312119-wzcas4zd	173	158	in	in	IN
cord-312119-wzcas4zd	173	159	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	173	160	coli	coli	NNS
cord-312119-wzcas4zd	173	161	isolated	isolate	VBN
cord-312119-wzcas4zd	173	162	from	from	IN
cord-312119-wzcas4zd	173	163	piglets	piglet	NNS
cord-312119-wzcas4zd	173	164	with	with	IN
cord-312119-wzcas4zd	173	165	neonatal	neonatal	JJ
cord-312119-wzcas4zd	173	166	and	and	CC
cord-312119-wzcas4zd	173	167	post	post	JJ
cord-312119-wzcas4zd	173	168	-	-	JJ
cord-312119-wzcas4zd	173	169	weaning	weaning	JJ
cord-312119-wzcas4zd	173	170	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	173	171	in	in	IN
cord-312119-wzcas4zd	173	172	Japan	Japan	NNP
cord-312119-wzcas4zd	173	173	Antibodies	Antibodies	NNP
cord-312119-wzcas4zd	173	174	derived	derive	VBN
cord-312119-wzcas4zd	173	175	from	from	IN
cord-312119-wzcas4zd	173	176	an	an	DT
cord-312119-wzcas4zd	173	177	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	173	178	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	173	179	coli	coli	NNS
cord-312119-wzcas4zd	173	180	(	(	-LRB-
cord-312119-wzcas4zd	173	181	ETEC	ETEC	NNP
cord-312119-wzcas4zd	173	182	)	)	-RRB-
cord-312119-wzcas4zd	173	183	adhesin	adhesin	JJ
cord-312119-wzcas4zd	173	184	tip	tip	NN
cord-312119-wzcas4zd	173	185	MEFA	MEFA	NNP
cord-312119-wzcas4zd	173	186	(	(	-LRB-
cord-312119-wzcas4zd	173	187	multiepitope	multiepitope	NNP
cord-312119-wzcas4zd	173	188	fusion	fusion	NN
cord-312119-wzcas4zd	173	189	antigen	antigen	NNP
cord-312119-wzcas4zd	173	190	)	)	-RRB-
cord-312119-wzcas4zd	173	191	against	against	IN
cord-312119-wzcas4zd	173	192	adherence	adherence	NN
cord-312119-wzcas4zd	173	193	of	of	IN
cord-312119-wzcas4zd	173	194	nine	nine	CD
cord-312119-wzcas4zd	173	195	ETEC	etec	JJ
cord-312119-wzcas4zd	173	196	adhesins	adhesin	NNS
cord-312119-wzcas4zd	173	197	:	:	:
cord-312119-wzcas4zd	174	1	CFA	CFA	NNP
cord-312119-wzcas4zd	174	2	/	/	SYM
cord-312119-wzcas4zd	174	3	I	I	NNP
cord-312119-wzcas4zd	174	4	,	,	,
cord-312119-wzcas4zd	174	5	CS1	CS1	NNP
cord-312119-wzcas4zd	174	6	,	,	,
cord-312119-wzcas4zd	174	7	CS2	CS2	NNP
cord-312119-wzcas4zd	174	8	,	,	,
cord-312119-wzcas4zd	174	9	CS3	CS3	NNP
cord-312119-wzcas4zd	174	10	,	,	,
cord-312119-wzcas4zd	174	11	CS4	CS4	NNP
cord-312119-wzcas4zd	174	12	,	,	,
cord-312119-wzcas4zd	174	13	CS5	CS5	NNP
cord-312119-wzcas4zd	174	14	,	,	,
cord-312119-wzcas4zd	174	15	CS6	CS6	NNP
cord-312119-wzcas4zd	174	16	,	,	,
cord-312119-wzcas4zd	174	17	CS21	CS21	NNP
cord-312119-wzcas4zd	174	18	and	and	CC
cord-312119-wzcas4zd	174	19	EtpA	EtpA	NNP
cord-312119-wzcas4zd	174	20	Diarrheagenic	Diarrheagenic	NNP
cord-312119-wzcas4zd	174	21	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	174	22	coli	coli	VBZ
cord-312119-wzcas4zd	174	23	Prevalence	prevalence	NN
cord-312119-wzcas4zd	174	24	of	of	IN
cord-312119-wzcas4zd	174	25	shiga	shiga	JJ
cord-312119-wzcas4zd	174	26	toxin	toxin	NN
cord-312119-wzcas4zd	174	27	genes	gene	NNS
cord-312119-wzcas4zd	174	28	among	among	IN
cord-312119-wzcas4zd	174	29	Escherichia	escherichia	NN
cord-312119-wzcas4zd	174	30	coli	coli	NNS
cord-312119-wzcas4zd	174	31	strains	strain	NNS
cord-312119-wzcas4zd	174	32	isolated	isolate	VBN
cord-312119-wzcas4zd	174	33	from	from	IN
cord-312119-wzcas4zd	174	34	pigs	pig	NNS
cord-312119-wzcas4zd	174	35	Prevalence	prevalence	NN
cord-312119-wzcas4zd	174	36	of	of	IN
cord-312119-wzcas4zd	174	37	virulence	virulence	NN
cord-312119-wzcas4zd	174	38	factors	factor	NNS
cord-312119-wzcas4zd	174	39	of	of	IN
cord-312119-wzcas4zd	174	40	Escherichia	escherichia	NN
cord-312119-wzcas4zd	174	41	coli	coli	VBZ
cord-312119-wzcas4zd	174	42	strains	strain	NNS
cord-312119-wzcas4zd	174	43	isolated	isolate	VBN
cord-312119-wzcas4zd	174	44	from	from	IN
cord-312119-wzcas4zd	174	45	diarrheic	diarrheic	NNS
cord-312119-wzcas4zd	174	46	and	and	CC
cord-312119-wzcas4zd	174	47	healthy	healthy	JJ
cord-312119-wzcas4zd	174	48	piglets	piglet	NNS
cord-312119-wzcas4zd	174	49	after	after	IN
cord-312119-wzcas4zd	174	50	weaning	wean	VBG
cord-312119-wzcas4zd	174	51	Frenquency	Frenquency	NNP
cord-312119-wzcas4zd	174	52	of	of	IN
cord-312119-wzcas4zd	174	53	virulence	virulence	NN
cord-312119-wzcas4zd	174	54	factors	factor	NNS
cord-312119-wzcas4zd	174	55	in	in	IN
cord-312119-wzcas4zd	174	56	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	174	57	coli	coli	NNS
cord-312119-wzcas4zd	174	58	isolated	isolate	VBN
cord-312119-wzcas4zd	174	59	from	from	IN
cord-312119-wzcas4zd	174	60	pigs	pig	NNS
cord-312119-wzcas4zd	174	61	with	with	IN
cord-312119-wzcas4zd	174	62	postweaning	postweane	VBG
cord-312119-wzcas4zd	174	63	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	174	64	and	and	CC
cord-312119-wzcas4zd	174	65	edema	edema	NN
cord-312119-wzcas4zd	174	66	disease	disease	NN
cord-312119-wzcas4zd	174	67	in	in	IN
cord-312119-wzcas4zd	174	68	North	North	NNP
cord-312119-wzcas4zd	174	69	Carolina	Carolina	NNP
cord-312119-wzcas4zd	174	70	.	.	.
cord-312119-wzcas4zd	175	1	Swine	Swine	NNP
cord-312119-wzcas4zd	175	2	Health	Health	NNP
cord-312119-wzcas4zd	175	3	Prod	Prod	NNP
cord-312119-wzcas4zd	175	4	Antibodies	Antibodies	NNP
cord-312119-wzcas4zd	175	5	derived	derive	VBD
cord-312119-wzcas4zd	175	6	from	from	IN
cord-312119-wzcas4zd	175	7	a	a	DT
cord-312119-wzcas4zd	175	8	toxoid	toxoid	NN
cord-312119-wzcas4zd	175	9	MEFA	MEFA	NNP
cord-312119-wzcas4zd	175	10	(	(	-LRB-
cord-312119-wzcas4zd	175	11	multiepitope	multiepitope	NNP
cord-312119-wzcas4zd	175	12	fusion	fusion	NN
cord-312119-wzcas4zd	175	13	antigen	antigen	NNP
cord-312119-wzcas4zd	175	14	)	)	-RRB-
cord-312119-wzcas4zd	175	15	show	show	VBP
cord-312119-wzcas4zd	175	16	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	175	17	activities	activity	NNS
cord-312119-wzcas4zd	175	18	against	against	IN
cord-312119-wzcas4zd	175	19	heat	heat	NN
cord-312119-wzcas4zd	175	20	-	-	HYPH
cord-312119-wzcas4zd	175	21	labile	labile	JJ
cord-312119-wzcas4zd	175	22	toxin	toxin	NN
cord-312119-wzcas4zd	175	23	(	(	-LRB-
cord-312119-wzcas4zd	175	24	LT	LT	NNP
cord-312119-wzcas4zd	175	25	)	)	-RRB-
cord-312119-wzcas4zd	175	26	,	,	,
cord-312119-wzcas4zd	175	27	heat	heat	NN
cord-312119-wzcas4zd	175	28	-	-	HYPH
cord-312119-wzcas4zd	175	29	stable	stable	JJ
cord-312119-wzcas4zd	175	30	toxins	toxin	NNS
cord-312119-wzcas4zd	175	31	(	(	-LRB-
cord-312119-wzcas4zd	175	32	STa	sta	NN
cord-312119-wzcas4zd	175	33	,	,	,
cord-312119-wzcas4zd	175	34	STb	STb	NNP
cord-312119-wzcas4zd	175	35	)	)	-RRB-
cord-312119-wzcas4zd	175	36	,	,	,
cord-312119-wzcas4zd	175	37	and	and	CC
cord-312119-wzcas4zd	175	38	Shiga	Shiga	NNP
cord-312119-wzcas4zd	175	39	toxin	toxin	NN
cord-312119-wzcas4zd	175	40	2e	2e	CD
cord-312119-wzcas4zd	175	41	(	(	-LRB-
cord-312119-wzcas4zd	175	42	Stx2e	Stx2e	NNP
cord-312119-wzcas4zd	175	43	)	)	-RRB-
cord-312119-wzcas4zd	175	44	of	of	IN
cord-312119-wzcas4zd	175	45	porcine	porcine	JJ
cord-312119-wzcas4zd	175	46	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	175	47	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	175	48	coli	coli	NNS
cord-312119-wzcas4zd	175	49	(	(	-LRB-
cord-312119-wzcas4zd	175	50	ETEC	ETEC	NNP
cord-312119-wzcas4zd	175	51	)	)	-RRB-
cord-312119-wzcas4zd	176	1	A	a	DT
cord-312119-wzcas4zd	176	2	tripartite	tripartite	JJ
cord-312119-wzcas4zd	176	3	fusion	fusion	NN
cord-312119-wzcas4zd	177	1	,	,	,
cord-312119-wzcas4zd	177	2	FaeG	FaeG	NNP
cord-312119-wzcas4zd	177	3	-	-	HYPH
cord-312119-wzcas4zd	177	4	FedF	FedF	NNP
cord-312119-wzcas4zd	177	5	-	-	HYPH
cord-312119-wzcas4zd	177	6	LT(192)A2	LT(192)A2	NNP
cord-312119-wzcas4zd	177	7	:	:	:
cord-312119-wzcas4zd	177	8	B	b	NN
cord-312119-wzcas4zd	177	9	,	,	,
cord-312119-wzcas4zd	177	10	of	of	IN
cord-312119-wzcas4zd	177	11	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	177	12	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	177	13	coli	coli	NNS
cord-312119-wzcas4zd	177	14	(	(	-LRB-
cord-312119-wzcas4zd	177	15	ETEC	ETEC	NNP
cord-312119-wzcas4zd	177	16	)	)	-RRB-
cord-312119-wzcas4zd	177	17	elicits	elicit	VBZ
cord-312119-wzcas4zd	177	18	antibodies	antibody	NNS
cord-312119-wzcas4zd	177	19	that	that	WDT
cord-312119-wzcas4zd	177	20	neutralize	neutralize	VBP
cord-312119-wzcas4zd	177	21	cholera	cholera	NN
cord-312119-wzcas4zd	177	22	toxin	toxin	NN
cord-312119-wzcas4zd	177	23	,	,	,
cord-312119-wzcas4zd	177	24	inhibit	inhibit	VB
cord-312119-wzcas4zd	177	25	adherence	adherence	NN
cord-312119-wzcas4zd	177	26	of	of	IN
cord-312119-wzcas4zd	177	27	K88	K88	NNP
cord-312119-wzcas4zd	177	28	(	(	-LRB-
cord-312119-wzcas4zd	177	29	F4	F4	NNP
cord-312119-wzcas4zd	177	30	)	)	-RRB-
cord-312119-wzcas4zd	177	31	and	and	CC
cord-312119-wzcas4zd	177	32	F18	F18	NNP
cord-312119-wzcas4zd	177	33	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	177	34	,	,	,
cord-312119-wzcas4zd	177	35	and	and	CC
cord-312119-wzcas4zd	177	36	protect	protect	VB
cord-312119-wzcas4zd	177	37	pigs	pig	NNS
cord-312119-wzcas4zd	177	38	against	against	IN
cord-312119-wzcas4zd	177	39	K88ac	K88ac	NNP
cord-312119-wzcas4zd	177	40	/	/	SYM
cord-312119-wzcas4zd	177	41	heat	heat	NN
cord-312119-wzcas4zd	177	42	-	-	HYPH
cord-312119-wzcas4zd	177	43	labile	labile	JJ
cord-312119-wzcas4zd	177	44	toxin	toxin	NN
cord-312119-wzcas4zd	177	45	infection	infection	NN
cord-312119-wzcas4zd	177	46	Multiepitope	Multiepitope	NNP
cord-312119-wzcas4zd	177	47	fusion	fusion	NN
cord-312119-wzcas4zd	177	48	antigen	antigen	NN
cord-312119-wzcas4zd	177	49	induces	induce	VBZ
cord-312119-wzcas4zd	177	50	broadly	broadly	RB
cord-312119-wzcas4zd	177	51	protective	protective	JJ
cord-312119-wzcas4zd	177	52	antibodies	antibody	NNS
cord-312119-wzcas4zd	177	53	that	that	WDT
cord-312119-wzcas4zd	177	54	prevent	prevent	VBP
cord-312119-wzcas4zd	177	55	adherence	adherence	NN
cord-312119-wzcas4zd	177	56	of	of	IN
cord-312119-wzcas4zd	177	57	Escherichia	escherichia	NN
cord-312119-wzcas4zd	177	58	coli	coli	NNS
cord-312119-wzcas4zd	177	59	strains	strain	NNS
cord-312119-wzcas4zd	177	60	expressing	express	VBG
cord-312119-wzcas4zd	177	61	colonization	colonization	NN
cord-312119-wzcas4zd	177	62	factor	factor	NN
cord-312119-wzcas4zd	177	63	antigen	antigen	NN
cord-312119-wzcas4zd	177	64	I	I	NNP
cord-312119-wzcas4zd	177	65	(	(	-LRB-
cord-312119-wzcas4zd	177	66	CFA	CFA	NNP
cord-312119-wzcas4zd	177	67	/	/	SYM
cord-312119-wzcas4zd	177	68	I	i	NN
cord-312119-wzcas4zd	177	69	)	)	-RRB-
cord-312119-wzcas4zd	177	70	Characterization	characterization	NN
cord-312119-wzcas4zd	177	71	of	of	IN
cord-312119-wzcas4zd	177	72	heat	heat	NN
cord-312119-wzcas4zd	177	73	-	-	HYPH
cord-312119-wzcas4zd	177	74	stable	stable	JJ
cord-312119-wzcas4zd	177	75	(	(	-LRB-
cord-312119-wzcas4zd	177	76	STa	sta	NN
cord-312119-wzcas4zd	177	77	)	)	-RRB-
cord-312119-wzcas4zd	177	78	toxoids	toxoid	NNS
cord-312119-wzcas4zd	177	79	of	of	IN
cord-312119-wzcas4zd	177	80	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	177	81	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	177	82	coli	coli	NNS
cord-312119-wzcas4zd	177	83	fused	fuse	VBN
cord-312119-wzcas4zd	177	84	to	to	IN
cord-312119-wzcas4zd	177	85	a	a	DT
cord-312119-wzcas4zd	177	86	double	double	JJ
cord-312119-wzcas4zd	177	87	mutant	mutant	JJ
cord-312119-wzcas4zd	177	88	heat	heat	NN
cord-312119-wzcas4zd	177	89	-	-	HYPH
cord-312119-wzcas4zd	177	90	labile	labile	JJ
cord-312119-wzcas4zd	177	91	toxin	toxin	NN
cord-312119-wzcas4zd	177	92	(	(	-LRB-
cord-312119-wzcas4zd	177	93	dmLT	dmLT	NNP
cord-312119-wzcas4zd	177	94	)	)	-RRB-
cord-312119-wzcas4zd	177	95	peptide	peptide	NN
cord-312119-wzcas4zd	177	96	in	in	IN
cord-312119-wzcas4zd	177	97	inducing	induce	VBG
cord-312119-wzcas4zd	177	98	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	177	99	anti	anti	JJ
cord-312119-wzcas4zd	177	100	-	-	JJ
cord-312119-wzcas4zd	177	101	STa	sta	JJ
cord-312119-wzcas4zd	177	102	antibodies	antibody	NNS
cord-312119-wzcas4zd	177	103	Genetic	genetic	JJ
cord-312119-wzcas4zd	177	104	fusions	fusion	NNS
cord-312119-wzcas4zd	177	105	of	of	IN
cord-312119-wzcas4zd	177	106	a	a	DT
cord-312119-wzcas4zd	177	107	CFA	CFA	NNP
cord-312119-wzcas4zd	177	108	/	/	SYM
cord-312119-wzcas4zd	177	109	I	I	NNP
cord-312119-wzcas4zd	177	110	/	/	SYM
cord-312119-wzcas4zd	177	111	II	II	NNP
cord-312119-wzcas4zd	177	112	/	/	SYM
cord-312119-wzcas4zd	177	113	IV	IV	NNP
cord-312119-wzcas4zd	177	114	MEFA	MEFA	NNP
cord-312119-wzcas4zd	177	115	(	(	-LRB-
cord-312119-wzcas4zd	177	116	multiepitope	multiepitope	NNP
cord-312119-wzcas4zd	177	117	fusion	fusion	NN
cord-312119-wzcas4zd	177	118	antigen	antigen	NNP
cord-312119-wzcas4zd	177	119	)	)	-RRB-
cord-312119-wzcas4zd	177	120	and	and	CC
cord-312119-wzcas4zd	177	121	a	a	DT
cord-312119-wzcas4zd	177	122	toxoid	toxoid	NN
cord-312119-wzcas4zd	177	123	fusion	fusion	NN
cord-312119-wzcas4zd	177	124	of	of	IN
cord-312119-wzcas4zd	177	125	heat	heat	NN
cord-312119-wzcas4zd	177	126	-	-	HYPH
cord-312119-wzcas4zd	177	127	stable	stable	JJ
cord-312119-wzcas4zd	177	128	toxin	toxin	NN
cord-312119-wzcas4zd	177	129	(	(	-LRB-
cord-312119-wzcas4zd	177	130	STa	sta	NN
cord-312119-wzcas4zd	177	131	)	)	-RRB-
cord-312119-wzcas4zd	177	132	and	and	CC
cord-312119-wzcas4zd	177	133	heat	heat	NN
cord-312119-wzcas4zd	177	134	-	-	HYPH
cord-312119-wzcas4zd	177	135	labile	labile	JJ
cord-312119-wzcas4zd	177	136	toxin	toxin	NN
cord-312119-wzcas4zd	177	137	(	(	-LRB-
cord-312119-wzcas4zd	177	138	LT	LT	NNP
cord-312119-wzcas4zd	177	139	)	)	-RRB-
cord-312119-wzcas4zd	177	140	of	of	IN
cord-312119-wzcas4zd	177	141	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	177	142	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	177	143	coli	coli	NNS
cord-312119-wzcas4zd	177	144	(	(	-LRB-
cord-312119-wzcas4zd	177	145	ETEC	ETEC	NNP
cord-312119-wzcas4zd	177	146	)	)	-RRB-
cord-312119-wzcas4zd	177	147	retain	retain	VB
cord-312119-wzcas4zd	177	148	broad	broad	JJ
cord-312119-wzcas4zd	177	149	anti	anti	JJ
cord-312119-wzcas4zd	177	150	-	-	JJ
cord-312119-wzcas4zd	177	151	CFA	cfa	JJ
cord-312119-wzcas4zd	177	152	and	and	CC
cord-312119-wzcas4zd	177	153	antitoxin	antitoxin	NN
cord-312119-wzcas4zd	177	154	antigenicity	antigenicity	NN
cord-312119-wzcas4zd	177	155	Oral	oral	JJ
cord-312119-wzcas4zd	177	156	immunization	immunization	NN
cord-312119-wzcas4zd	177	157	of	of	IN
cord-312119-wzcas4zd	177	158	a	a	DT
cord-312119-wzcas4zd	177	159	live	live	JJ
cord-312119-wzcas4zd	177	160	attenuated	attenuated	JJ
cord-312119-wzcas4zd	177	161	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	177	162	coli	coli	NNS
cord-312119-wzcas4zd	177	163	strain	strain	NN
cord-312119-wzcas4zd	177	164	expressing	express	VBG
cord-312119-wzcas4zd	177	165	a	a	DT
cord-312119-wzcas4zd	177	166	holotoxin	holotoxin	JJ
cord-312119-wzcas4zd	177	167	-	-	HYPH
cord-312119-wzcas4zd	177	168	structured	structure	VBN
cord-312119-wzcas4zd	177	169	adhesin	adhesin	NN
cord-312119-wzcas4zd	177	170	-	-	HYPH
cord-312119-wzcas4zd	177	171	toxoid	toxoid	NN
cord-312119-wzcas4zd	177	172	fusion	fusion	NN
cord-312119-wzcas4zd	177	173	(	(	-LRB-
cord-312119-wzcas4zd	177	174	1FaeG	1faeg	CD
cord-312119-wzcas4zd	177	175	-	-	HYPH
cord-312119-wzcas4zd	177	176	FedF	FedF	NNP
cord-312119-wzcas4zd	177	177	-	-	:
cord-312119-wzcas4zd	177	178	LTA2:5LTB	lta2:5ltb	NN
cord-312119-wzcas4zd	177	179	)	)	-RRB-
cord-312119-wzcas4zd	177	180	protected	protect	VBD
cord-312119-wzcas4zd	177	181	young	young	JJ
cord-312119-wzcas4zd	177	182	pigs	pig	NNS
cord-312119-wzcas4zd	177	183	against	against	IN
cord-312119-wzcas4zd	177	184	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	177	185	E.	E.	NNP
cord-312119-wzcas4zd	177	186	Coli	Coli	NNP
cord-312119-wzcas4zd	177	187	(	(	-LRB-
cord-312119-wzcas4zd	177	188	ETEC	ETEC	NNP
cord-312119-wzcas4zd	177	189	)	)	-RRB-
cord-312119-wzcas4zd	177	190	infection	infection	NN
cord-312119-wzcas4zd	177	191	Prediction	prediction	NN
cord-312119-wzcas4zd	177	192	methods	method	NNS
cord-312119-wzcas4zd	177	193	for	for	IN
cord-312119-wzcas4zd	177	194	B	b	NN
cord-312119-wzcas4zd	177	195	-	-	HYPH
cord-312119-wzcas4zd	177	196	cell	cell	NN
cord-312119-wzcas4zd	177	197	epitopes	epitope	NNS
cord-312119-wzcas4zd	178	1	Avirulent	Avirulent	NNP
cord-312119-wzcas4zd	178	2	K88	K88	NNP
cord-312119-wzcas4zd	178	3	(	(	-LRB-
cord-312119-wzcas4zd	178	4	F4	F4	NNP
cord-312119-wzcas4zd	178	5	)	)	-RRB-
cord-312119-wzcas4zd	178	6	+	+	CC
cord-312119-wzcas4zd	179	1	Escherichia	escherichia	NN
cord-312119-wzcas4zd	179	2	coli	coli	VBZ
cord-312119-wzcas4zd	179	3	strains	strain	NNS
cord-312119-wzcas4zd	179	4	constructed	construct	VBN
cord-312119-wzcas4zd	179	5	to	to	TO
cord-312119-wzcas4zd	179	6	express	express	VB
cord-312119-wzcas4zd	179	7	modified	modified	JJ
cord-312119-wzcas4zd	179	8	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	179	9	protect	protect	VB
cord-312119-wzcas4zd	179	10	young	young	JJ
cord-312119-wzcas4zd	179	11	piglets	piglet	NNS
cord-312119-wzcas4zd	179	12	from	from	IN
cord-312119-wzcas4zd	179	13	challenge	challenge	NN
cord-312119-wzcas4zd	179	14	with	with	IN
cord-312119-wzcas4zd	179	15	a	a	DT
cord-312119-wzcas4zd	179	16	virulent	virulent	JJ
cord-312119-wzcas4zd	179	17	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	179	18	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	179	19	coli	coli	NNS
cord-312119-wzcas4zd	179	20	strain	strain	NN
cord-312119-wzcas4zd	179	21	that	that	WDT
cord-312119-wzcas4zd	179	22	expresses	express	VBZ
cord-312119-wzcas4zd	179	23	the	the	DT
cord-312119-wzcas4zd	179	24	same	same	JJ
cord-312119-wzcas4zd	179	25	adhesin	adhesin	NN
cord-312119-wzcas4zd	179	26	and	and	CC
cord-312119-wzcas4zd	179	27	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	179	28	Characterization	characterization	NN
cord-312119-wzcas4zd	179	29	of	of	IN
cord-312119-wzcas4zd	179	30	the	the	DT
cord-312119-wzcas4zd	179	31	adhesin	adhesin	NN
cord-312119-wzcas4zd	179	32	of	of	IN
cord-312119-wzcas4zd	179	33	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	179	34	coli	coli	VBZ
cord-312119-wzcas4zd	179	35	F18	F18	NNP
cord-312119-wzcas4zd	179	36	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	179	37	Mapping	map	VBG
cord-312119-wzcas4zd	179	38	the	the	DT
cord-312119-wzcas4zd	179	39	binding	bind	VBG
cord-312119-wzcas4zd	179	40	domain	domain	NN
cord-312119-wzcas4zd	179	41	of	of	IN
cord-312119-wzcas4zd	179	42	the	the	DT
cord-312119-wzcas4zd	179	43	F18	F18	NNP
cord-312119-wzcas4zd	179	44	fimbrial	fimbrial	JJ
cord-312119-wzcas4zd	179	45	adhesin	adhesin	NNP
cord-312119-wzcas4zd	179	46	Observations	Observations	NNPS
cord-312119-wzcas4zd	179	47	on	on	IN
cord-312119-wzcas4zd	179	48	the	the	DT
cord-312119-wzcas4zd	179	49	pathogenic	pathogenic	JJ
cord-312119-wzcas4zd	179	50	properties	property	NNS
cord-312119-wzcas4zd	179	51	of	of	IN
cord-312119-wzcas4zd	179	52	the	the	DT
cord-312119-wzcas4zd	179	53	K88	K88	NNP
cord-312119-wzcas4zd	179	54	,	,	,
cord-312119-wzcas4zd	179	55	Hly	Hly	NNP
cord-312119-wzcas4zd	179	56	and	and	CC
cord-312119-wzcas4zd	179	57	Ent	Ent	NNP
cord-312119-wzcas4zd	179	58	plasmids	plasmid	NNS
cord-312119-wzcas4zd	179	59	of	of	IN
cord-312119-wzcas4zd	179	60	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	179	61	coli	coli	NNS
cord-312119-wzcas4zd	179	62	with	with	IN
cord-312119-wzcas4zd	179	63	particular	particular	JJ
cord-312119-wzcas4zd	179	64	reference	reference	NN
cord-312119-wzcas4zd	179	65	to	to	IN
cord-312119-wzcas4zd	179	66	porcine	porcine	JJ
cord-312119-wzcas4zd	179	67	diarrhoea	diarrhoea	NN
cord-312119-wzcas4zd	180	1	Current	current	JJ
cord-312119-wzcas4zd	180	2	and	and	CC
cord-312119-wzcas4zd	180	3	future	future	JJ
cord-312119-wzcas4zd	180	4	vaccines	vaccine	NNS
cord-312119-wzcas4zd	180	5	could	could	MD
cord-312119-wzcas4zd	180	6	help	help	VB
cord-312119-wzcas4zd	180	7	reduce	reduce	VB
cord-312119-wzcas4zd	180	8	reliance	reliance	NN
cord-312119-wzcas4zd	180	9	on	on	IN
cord-312119-wzcas4zd	180	10	antibiotics	antibiotic	NNS
cord-312119-wzcas4zd	180	11	,	,	,
cord-312119-wzcas4zd	180	12	AMR	AMR	NNP
cord-312119-wzcas4zd	180	13	says	say	VBZ
cord-312119-wzcas4zd	180	14	Health	Health	NNP
cord-312119-wzcas4zd	180	15	Monitoring	Monitoring	NNP
cord-312119-wzcas4zd	180	16	Syst	Syst	NNP
cord-312119-wzcas4zd	180	17	.	.	.
cord-312119-wzcas4zd	181	1	Part	part	NN
cord-312119-wzcas4zd	181	2	II	ii	CD
cord-312119-wzcas4zd	182	1	:	:	:
cord-312119-wzcas4zd	182	2	Reference	reference	NN
cord-312119-wzcas4zd	182	3	for	for	IN
cord-312119-wzcas4zd	182	4	Swine	Swine	NNP
cord-312119-wzcas4zd	182	5	Health	Health	NNP
cord-312119-wzcas4zd	182	6	and	and	CC
cord-312119-wzcas4zd	182	7	Health	Health	NNP
cord-312119-wzcas4zd	182	8	Management	Management	NNP
cord-312119-wzcas4zd	182	9	in	in	IN
cord-312119-wzcas4zd	182	10	the	the	DT
cord-312119-wzcas4zd	182	11	United	United	NNP
cord-312119-wzcas4zd	182	12	States	States	NNP
cord-312119-wzcas4zd	182	13	Receptor	Receptor	NNP
cord-312119-wzcas4zd	182	14	-	-	HYPH
cord-312119-wzcas4zd	182	15	dependent	dependent	JJ
cord-312119-wzcas4zd	182	16	immune	immune	JJ
cord-312119-wzcas4zd	182	17	responses	response	NNS
cord-312119-wzcas4zd	182	18	in	in	IN
cord-312119-wzcas4zd	182	19	pigs	pig	NNS
cord-312119-wzcas4zd	182	20	after	after	IN
cord-312119-wzcas4zd	182	21	oral	oral	JJ
cord-312119-wzcas4zd	182	22	immunization	immunization	NN
cord-312119-wzcas4zd	182	23	with	with	IN
cord-312119-wzcas4zd	182	24	F4	F4	NNP
cord-312119-wzcas4zd	182	25	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	183	1	Different	different	JJ
cord-312119-wzcas4zd	183	2	kinetic	kinetic	NN
cord-312119-wzcas4zd	183	3	of	of	IN
cord-312119-wzcas4zd	183	4	antibody	antibody	NN
cord-312119-wzcas4zd	183	5	responses	response	NNS
cord-312119-wzcas4zd	183	6	following	follow	VBG
cord-312119-wzcas4zd	183	7	infection	infection	NN
cord-312119-wzcas4zd	183	8	of	of	IN
cord-312119-wzcas4zd	183	9	newly	newly	RB
cord-312119-wzcas4zd	183	10	weaned	wean	VBN
cord-312119-wzcas4zd	183	11	pigs	pig	NNS
cord-312119-wzcas4zd	183	12	with	with	IN
cord-312119-wzcas4zd	183	13	an	an	DT
cord-312119-wzcas4zd	183	14	F4	F4	NNP
cord-312119-wzcas4zd	183	15	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	183	16	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	183	17	coli	coli	NNS
cord-312119-wzcas4zd	183	18	strain	strain	NN
cord-312119-wzcas4zd	183	19	or	or	CC
cord-312119-wzcas4zd	183	20	an	an	DT
cord-312119-wzcas4zd	183	21	F18	F18	NNP
cord-312119-wzcas4zd	183	22	verotoxigenic	verotoxigenic	NN
cord-312119-wzcas4zd	183	23	Escherichia	escherichia	NN
cord-312119-wzcas4zd	183	24	coli	coli	NNS
cord-312119-wzcas4zd	183	25	strain	strain	VBP
cord-312119-wzcas4zd	183	26	Mucosal	Mucosal	NNP
cord-312119-wzcas4zd	183	27	immunization	immunization	NN
cord-312119-wzcas4zd	183	28	of	of	IN
cord-312119-wzcas4zd	183	29	piglets	piglet	NNS
cord-312119-wzcas4zd	183	30	with	with	IN
cord-312119-wzcas4zd	183	31	purified	purify	VBN
cord-312119-wzcas4zd	183	32	F18	F18	NNP
cord-312119-wzcas4zd	183	33	fimbriae	fimbriae	NN
cord-312119-wzcas4zd	183	34	does	do	VBZ
cord-312119-wzcas4zd	183	35	not	not	RB
cord-312119-wzcas4zd	183	36	protect	protect	VB
cord-312119-wzcas4zd	183	37	against	against	IN
cord-312119-wzcas4zd	183	38	F18	F18	NNP
cord-312119-wzcas4zd	183	39	+	+	CC
cord-312119-wzcas4zd	183	40	Escherichia	escherichia	NN
cord-312119-wzcas4zd	183	41	coli	coli	NNS
cord-312119-wzcas4zd	183	42	infection	infection	NN
cord-312119-wzcas4zd	183	43	Serotypes	Serotypes	NNP
cord-312119-wzcas4zd	183	44	,	,	,
cord-312119-wzcas4zd	183	45	virulence	virulence	NN
cord-312119-wzcas4zd	183	46	genes	gene	NNS
cord-312119-wzcas4zd	183	47	,	,	,
cord-312119-wzcas4zd	183	48	intimin	intimin	NN
cord-312119-wzcas4zd	183	49	types	type	NNS
cord-312119-wzcas4zd	183	50	and	and	CC
cord-312119-wzcas4zd	183	51	PFGE	PFGE	NNP
cord-312119-wzcas4zd	183	52	profiles	profile	NNS
cord-312119-wzcas4zd	183	53	of	of	IN
cord-312119-wzcas4zd	183	54	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	183	55	coli	coli	NNS
cord-312119-wzcas4zd	183	56	isolated	isolate	VBN
cord-312119-wzcas4zd	183	57	from	from	IN
cord-312119-wzcas4zd	183	58	piglets	piglet	NNS
cord-312119-wzcas4zd	183	59	with	with	IN
cord-312119-wzcas4zd	183	60	diarrhoea	diarrhoea	NN
cord-312119-wzcas4zd	183	61	in	in	IN
cord-312119-wzcas4zd	183	62	Slovakia	Slovakia	NNP
cord-312119-wzcas4zd	183	63	Considerations	Considerations	NNPS
cord-312119-wzcas4zd	183	64	for	for	IN
cord-312119-wzcas4zd	183	65	development	development	NN
cord-312119-wzcas4zd	183	66	of	of	IN
cord-312119-wzcas4zd	183	67	whole	whole	JJ
cord-312119-wzcas4zd	183	68	cell	cell	NN
cord-312119-wzcas4zd	183	69	bacterial	bacterial	JJ
cord-312119-wzcas4zd	183	70	vaccines	vaccine	NNS
cord-312119-wzcas4zd	183	71	to	to	TO
cord-312119-wzcas4zd	183	72	prevent	prevent	VB
cord-312119-wzcas4zd	183	73	diarrheal	diarrheal	JJ
cord-312119-wzcas4zd	183	74	diseases	disease	NNS
cord-312119-wzcas4zd	183	75	in	in	IN
cord-312119-wzcas4zd	183	76	children	child	NNS
cord-312119-wzcas4zd	183	77	in	in	IN
cord-312119-wzcas4zd	183	78	developing	develop	VBG
cord-312119-wzcas4zd	183	79	countries	country	NNS
cord-312119-wzcas4zd	183	80	Progress	Progress	NNP
cord-312119-wzcas4zd	183	81	and	and	CC
cord-312119-wzcas4zd	183	82	challenges	challenge	NNS
cord-312119-wzcas4zd	183	83	in	in	IN
cord-312119-wzcas4zd	183	84	vaccine	vaccine	NN
cord-312119-wzcas4zd	183	85	development	development	NN
cord-312119-wzcas4zd	183	86	against	against	IN
cord-312119-wzcas4zd	183	87	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	183	88	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	183	89	coli	coli	NNS
cord-312119-wzcas4zd	183	90	(	(	-LRB-
cord-312119-wzcas4zd	183	91	ETEC	ETEC	NNP
cord-312119-wzcas4zd	183	92	)	)	-RRB-
cord-312119-wzcas4zd	184	1	-associated	-associate	VBN
cord-312119-wzcas4zd	185	1	porcine	porcine	JJ
cord-312119-wzcas4zd	185	2	post	post	JJ
cord-312119-wzcas4zd	185	3	-	-	JJ
cord-312119-wzcas4zd	185	4	weaning	weaning	JJ
cord-312119-wzcas4zd	185	5	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	185	6	(	(	-LRB-
cord-312119-wzcas4zd	185	7	PWD	pwd	NN
cord-312119-wzcas4zd	185	8	)	)	-RRB-
cord-312119-wzcas4zd	185	9	Progress	progress	NN
cord-312119-wzcas4zd	185	10	and	and	CC
cord-312119-wzcas4zd	185	11	hurdles	hurdle	NNS
cord-312119-wzcas4zd	185	12	in	in	IN
cord-312119-wzcas4zd	185	13	the	the	DT
cord-312119-wzcas4zd	185	14	development	development	NN
cord-312119-wzcas4zd	185	15	of	of	IN
cord-312119-wzcas4zd	185	16	vaccines	vaccine	NNS
cord-312119-wzcas4zd	185	17	against	against	IN
cord-312119-wzcas4zd	185	18	enterotoxigenic	enterotoxigenic	NNP
cord-312119-wzcas4zd	185	19	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	185	20	coli	coli	NNS
cord-312119-wzcas4zd	185	21	in	in	IN
cord-312119-wzcas4zd	185	22	humans	human	NNS
cord-312119-wzcas4zd	185	23	Significance	significance	NN
cord-312119-wzcas4zd	185	24	of	of	IN
cord-312119-wzcas4zd	185	25	heat	heat	NN
cord-312119-wzcas4zd	185	26	-	-	HYPH
cord-312119-wzcas4zd	185	27	stable	stable	JJ
cord-312119-wzcas4zd	185	28	and	and	CC
cord-312119-wzcas4zd	185	29	heat	heat	NN
cord-312119-wzcas4zd	185	30	-	-	HYPH
cord-312119-wzcas4zd	185	31	labile	labile	JJ
cord-312119-wzcas4zd	185	32	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	185	33	in	in	IN
cord-312119-wzcas4zd	185	34	porcine	porcine	JJ
cord-312119-wzcas4zd	185	35	colibacillosis	colibacillosis	NN
cord-312119-wzcas4zd	185	36	in	in	IN
cord-312119-wzcas4zd	185	37	an	an	DT
cord-312119-wzcas4zd	185	38	additive	additive	NN
cord-312119-wzcas4zd	185	39	model	model	NN
cord-312119-wzcas4zd	185	40	for	for	IN
cord-312119-wzcas4zd	185	41	pathogenicity	pathogenicity	NN
cord-312119-wzcas4zd	185	42	studies	study	NNS
cord-312119-wzcas4zd	185	43	Prevalence	prevalence	NN
cord-312119-wzcas4zd	185	44	of	of	IN
cord-312119-wzcas4zd	185	45	virulence	virulence	NN
cord-312119-wzcas4zd	185	46	genes	gene	NNS
cord-312119-wzcas4zd	185	47	in	in	IN
cord-312119-wzcas4zd	185	48	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	185	49	coli	coli	VBZ
cord-312119-wzcas4zd	185	50	strains	strain	NNS
cord-312119-wzcas4zd	185	51	recently	recently	RB
cord-312119-wzcas4zd	185	52	isolated	isolate	VBN
cord-312119-wzcas4zd	185	53	from	from	IN
cord-312119-wzcas4zd	185	54	young	young	JJ
cord-312119-wzcas4zd	185	55	pigs	pig	NNS
cord-312119-wzcas4zd	185	56	with	with	IN
cord-312119-wzcas4zd	185	57	diarrhea	diarrhea	NN
cord-312119-wzcas4zd	185	58	in	in	IN
cord-312119-wzcas4zd	185	59	the	the	DT
cord-312119-wzcas4zd	185	60	US	US	NNP
cord-312119-wzcas4zd	185	61	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	185	62	coli	coli	NNS
cord-312119-wzcas4zd	185	63	constructs	construct	NNS
cord-312119-wzcas4zd	185	64	expressing	express	VBG
cord-312119-wzcas4zd	185	65	human	human	JJ
cord-312119-wzcas4zd	185	66	or	or	CC
cord-312119-wzcas4zd	185	67	porcine	porcine	JJ
cord-312119-wzcas4zd	185	68	enterotoxins	enterotoxin	NNS
cord-312119-wzcas4zd	186	1	induce	induce	VB
cord-312119-wzcas4zd	186	2	identical	identical	JJ
cord-312119-wzcas4zd	186	3	diarrheal	diarrheal	JJ
cord-312119-wzcas4zd	186	4	diseases	disease	NNS
cord-312119-wzcas4zd	186	5	in	in	IN
cord-312119-wzcas4zd	186	6	a	a	DT
cord-312119-wzcas4zd	186	7	piglet	piglet	NN
cord-312119-wzcas4zd	186	8	infection	infection	NN
cord-312119-wzcas4zd	186	9	model	model	NN
cord-312119-wzcas4zd	186	10	Genetic	genetic	JJ
cord-312119-wzcas4zd	186	11	fusions	fusion	NNS
cord-312119-wzcas4zd	186	12	of	of	IN
cord-312119-wzcas4zd	186	13	heat	heat	NN
cord-312119-wzcas4zd	186	14	-	-	HYPH
cord-312119-wzcas4zd	186	15	labile	labile	JJ
cord-312119-wzcas4zd	186	16	(	(	-LRB-
cord-312119-wzcas4zd	186	17	LT	LT	NNP
cord-312119-wzcas4zd	186	18	)	)	-RRB-
cord-312119-wzcas4zd	186	19	and	and	CC
cord-312119-wzcas4zd	186	20	heat	heat	NN
cord-312119-wzcas4zd	186	21	-	-	HYPH
cord-312119-wzcas4zd	186	22	stable	stable	JJ
cord-312119-wzcas4zd	186	23	(	(	-LRB-
cord-312119-wzcas4zd	186	24	ST	ST	NNP
cord-312119-wzcas4zd	186	25	)	)	-RRB-
cord-312119-wzcas4zd	186	26	toxoids	toxoid	NNS
cord-312119-wzcas4zd	186	27	of	of	IN
cord-312119-wzcas4zd	186	28	porcine	porcine	JJ
cord-312119-wzcas4zd	186	29	enterotoxigenic	enterotoxigenic	JJ
cord-312119-wzcas4zd	186	30	Escherichia	Escherichia	NNP
cord-312119-wzcas4zd	186	31	coli	coli	NNS
cord-312119-wzcas4zd	186	32	elicit	elicit	VBP
cord-312119-wzcas4zd	186	33	neutralizing	neutralize	VBG
cord-312119-wzcas4zd	186	34	anti	anti	JJ
cord-312119-wzcas4zd	186	35	-	-	JJ
cord-312119-wzcas4zd	186	36	LT	LT	NNP
cord-312119-wzcas4zd	186	37	and	and	CC
cord-312119-wzcas4zd	186	38	anti	anti	JJ
cord-312119-wzcas4zd	186	39	-	-	JJ
cord-312119-wzcas4zd	186	40	STa	sta	JJ
cord-312119-wzcas4zd	186	41	antibodies	antibody	NNS
cord-312119-wzcas4zd	186	42	We	-PRON-	PRP
cord-312119-wzcas4zd	186	43	thank	thank	VBP
cord-312119-wzcas4zd	186	44	Dr.	Dr.	NNP
cord-312119-wzcas4zd	186	45	B	B	NNP
cord-312119-wzcas4zd	186	46	Schultz	Schultz	NNP
cord-312119-wzcas4zd	186	47	(	(	-LRB-
cord-312119-wzcas4zd	186	48	Kansas	Kansas	NNP
cord-312119-wzcas4zd	186	49	State	State	NNP
cord-312119-wzcas4zd	186	50	University	University	NNP
cord-312119-wzcas4zd	186	51	)	)	-RRB-
cord-312119-wzcas4zd	186	52	for	for	IN
cord-312119-wzcas4zd	186	53	providing	provide	VBG
cord-312119-wzcas4zd	186	54	pig	pig	NN
cord-312119-wzcas4zd	186	55	cell	cell	NN
cord-312119-wzcas4zd	186	56	line	line	NN
cord-312119-wzcas4zd	186	57	IPEC	IPEC	NNP
cord-312119-wzcas4zd	186	58	-	-	HYPH
cord-312119-wzcas4zd	186	59	J2	J2	NNP
cord-312119-wzcas4zd	186	60	.	.	.
cord-312119-wzcas4zd	187	1	This	this	DT
cord-312119-wzcas4zd	187	2	work	work	NN
cord-312119-wzcas4zd	187	3	was	be	VBD
cord-312119-wzcas4zd	187	4	funded	fund	VBN
cord-312119-wzcas4zd	187	5	by	by	IN
cord-312119-wzcas4zd	187	6	USDA	USDA	NNP
cord-312119-wzcas4zd	187	7	-	-	HYPH
cord-312119-wzcas4zd	187	8	NIFA	NIFA	NNP
cord-312119-wzcas4zd	187	9	Agriculture	Agriculture	NNP
cord-312119-wzcas4zd	187	10	and	and	CC
cord-312119-wzcas4zd	187	11	Food	Food	NNP
cord-312119-wzcas4zd	187	12	Research	Research	NNP
cord-312119-wzcas4zd	187	13	Initiative	Initiative	NNP
cord-312119-wzcas4zd	187	14	Competitive	Competitive	NNP
cord-312119-wzcas4zd	187	15	Grant	Grant	NNP
cord-312119-wzcas4zd	187	16	No	no	NN
cord-312119-wzcas4zd	187	17	.	.	NN
cord-312119-wzcas4zd	187	18	2017	2017	CD
cord-312119-wzcas4zd	187	19	-	-	HYPH
cord-312119-wzcas4zd	187	20	67015	67015	CD
cord-312119-wzcas4zd	187	21	-	-	SYM
cord-312119-wzcas4zd	187	22	26632	26632	CD
cord-312119-wzcas4zd	187	23	.	.	.
cord-312119-wzcas4zd	187	24	 	 	_SP
cord-312119-wzcas4zd	188	1	Supplementary	supplementary	JJ
cord-312119-wzcas4zd	188	2	material	material	NN
cord-312119-wzcas4zd	188	3	related	relate	VBN
cord-312119-wzcas4zd	188	4	to	to	IN
cord-312119-wzcas4zd	188	5	this	this	DT
cord-312119-wzcas4zd	188	6	article	article	NN
cord-312119-wzcas4zd	188	7	can	can	MD
cord-312119-wzcas4zd	188	8	be	be	VB
cord-312119-wzcas4zd	188	9	found	find	VBN
cord-312119-wzcas4zd	188	10	,	,	,
cord-312119-wzcas4zd	188	11	in	in	IN
cord-312119-wzcas4zd	188	12	the	the	DT
cord-312119-wzcas4zd	188	13	online	online	JJ
cord-312119-wzcas4zd	188	14	version	version	NN
cord-312119-wzcas4zd	188	15	,	,	,
cord-312119-wzcas4zd	188	16	at	at	IN
cord-312119-wzcas4zd	188	17	doi	doi	NN
cord-312119-wzcas4zd	189	1	:	:	:
cord-312119-wzcas4zd	189	2	https://doi.org/10.1016/j.vetmic.2019.02.015	https://doi.org/10.1016/j.vetmic.2019.02.015	''
cord-312119-wzcas4zd	189	3	.	.	.