id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-288309-6pw7t512	Kusters, J. G.	Sequence evidence for RNA recombination in field isolates of avian coronavirus infectious bronchitis virus	1990-12-31		.txt	text/plain	1972	164	68	J.; Niesters, H.G.M.; van der Zeijst, B.A.M. title: Sequence evidence for RNA recombination in field isolates of avian coronavirus infectious bronchitis virus Nucleotide sequences of eight IBV isolates in a region of the genome suspected to contain recombination, were aligned and compared. To address the question of the frequency of recombination in the generation of new field isolates the nucleotide sequences in five windows of homologous sequences of the genomes of eight IBV strains have been compared. With the murine coronavirus MHV a high frequency of recombination was found both in vitro and in mouse brain after infection with a ts mutant of MHV strain A59 and wild type JHM-virus 18'19 Phylogenetic trees constructed from five different windows of the genomes of eight IBV strains were used to detect crossover events. Cloning and sequencing of genes encoding structural proteins of avian infectious bronchitis virus	./cache/cord-288309-6pw7t512.txt	./txt/cord-288309-6pw7t512.txt