id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-266745-jit1xeqc	Liou, Jenn-Fa	Passive protection effect of chicken egg yolk immunoglobulins on enterovirus 71 infected mice	2010-11-29		.txt	text/plain	5708	272	52	title: Passive protection effect of chicken egg yolk immunoglobulins on enterovirus 71 infected mice The results of the neutralization effect of specific IgY in EV71-challenged mice demonstrate that the EV71-specific IgY, either by intraperitoneal injection or oral administration, was able to significantly reduce the morbidity and mortality in EV71 infected mice pups. This study was subjected to produce IgY against enterovirus 71 (anti-EV71 IgY) and evaluated the inhibition effects of specific IgY on EV71, including in vitro virus neutralization test and in vivo ICR mice model. In trial 1, we challenged 1-day-old mice with a mouse-adapted EV71 strain MP4 by intraperitoneally administering a dosage of 10 5 pfu per mouse, and treated with specific IgY of neutralization titer 64. This indicates that the orally fed specific IgY effectively neutralized the viral attack in the gastroenteric duct, thereby blocking the infection of virus in challenged mice.	./cache/cord-266745-jit1xeqc.txt	./txt/cord-266745-jit1xeqc.txt