id author title date pages extension mime words sentences flesch summary cache txt cord-262940-eyejnexx Liu, Genmei Assembly and immunogenicity of coronavirus-like particles carrying infectious bronchitis virus M and S proteins 2013-11-12 .txt text/plain 3853 175 49 In the present study, we assembled IBV VLPs containing M and S proteins using a baculovirus expression system and we further evaluated the VLPs immune responses in mice and chickens. The results showed that, 2 weeks after the primary vaccination (day 14), both of VLPs and inactivated H120 groups could not detected serum IgG titers, and the differences between these and PBS groups were not statistically significant (P > 0.05); but following the second immunization (day 28), the IgG titers of the VLPs and inactivated H120 groups increased (Fig. 6 ) and were significantly higher (P < 0.01) than the PBS group. The results showed that VLPs and inactivated H120 groups had statistically significantly higher neutralizing antibody titers (P < 0.01) than the PBS group (Fig. 7) . Virus like particles (VLPs) and inactivated H120 groups had significantly higher neutralizing antibody titers (P < 0.01) than the PBS group. ./cache/cord-262940-eyejnexx.txt ./txt/cord-262940-eyejnexx.txt