id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-010279-ytnv0map	Bahnemann, Hans G.	Inactivation of viral antigens for vaccine preparation with particular reference to the application of binary ethylenimine	2002-11-12		.txt	text/plain	3479	198	47	The preparation and application of the aziridine compound binary ethylenimine (BEI) and the necessary conditions for and controls of the inactivation process are described and discussed. The first report of a (bacterial) virus inactivation by ethylenimine, the basic aziridine substance, was published in 1955 by Raettig and Uecker Is. Hurst in 1957 x6 was of the opinion that vaccines prepared with AEI as inactivant were antigenically superior to vaccines inactivated with formaldehyde and would guarantee inactivation of the virus. In 1961 Uecker 22 reported the linearity of inactivation of bacterial viruses by ethylenimine derivatives and Graves and Arlinghaus described in 1967 the linearity of AEI inactivation of foot-and-mouth disease virus 23. Formaldehyde inactivation of foot-and-mouth disease virus as applied to vaccine preparation Binary ethylenimine as an inactivant for foot-and-mouth disease virus and its application for vaccine production	./cache/cord-010279-ytnv0map.txt	./txt/cord-010279-ytnv0map.txt