cord-011297-4um9w2dx	2019	
cord-028923-gzqd5g0k	2020	
cord-029137-mck5cmn7	2020	
cord-035099-8yk0dzxf	2020	The assessment process of this patient has been supported by an innovative multi-systemic tool developed in view of the COVID-19 clinical consequences and a systemic evaluation of motor functions by the Frail''BESTest. Aged adults who survive COVID-19 could present several frailty criteria following respiratory distress and may sometimes need to spend several days in an intensive care unit. Considering the physiotherapeutic diagnosis of Mr. P, as well as the agespecific lung physiology of the patient [26] , some cardiopulmonary rehabilitation exercises allowing both the maintenance of ventilator functions and the improvement of hematosis can be proposed. The four assessments performed by the specific COVID-19 evaluation showed an overall improvement of the patient in several functions. In our opinion, it is important to understand that the issue is not only to rescue a patient from their acute respiratory problem, but more so to prevent the functional dependency associated with the infection''s consequences, especially in intensive care units where chronic diseases are frequently acquired.
cord-254631-80sg4uvd	2020	Posterior reversible encephalopathy syndrome (PRES) is a clinical syndrome that can include headache, altered consciousness, visual disturbances, and seizures, usually related to autoregulatory cerebral failure and hypertension. We present a case of a 66-year-old woman with severe pneumonia by SARS-CoV-2 who developed a posterior reversible encephalopathy syndrome with a typical clinical and radiological presentation, after being treated with anti-interleukin treatment (anakinra and tocilizumab) following local guidelines. We report a case of posterior reversible encephalopathy syndrome in a patient with COVID-19 disease, possibly related to anti-IL-1 or anti-IL-6, suggesting that anti-interleukin treatments may cause this syndrome, at least in patients with predisposing conditions such as infections and hydroelectrolytic disorders. Considering the infectious background, the immunomodulatory treatments, modest hypertension in the hours before the symptoms, and the distribution of the lesions on the CT scan, the most likely diagnosis is posterior reversible encephalopathy syndrome (PRES) [1] [2] [3] [4] [5] . Posterior reversible encephalopathy syndrome: associated clinical and radiologic findings
cord-255047-0kr4y753	2020	
cord-255357-oar2pttf	2020	title: Kawasaki Disease and Invasive Pneumococcal Infection In the morning, she developed five out of six major KD symptoms (except for lip findings), and intravenous immunoglobulin (2 g/kg; IVIG) and oral aspirin (30 mg/kg/day) were started according to the definite diagnosis of KD with a Kobayashi score of 4 [2] . The blood culture became positive for GPC in the evening, and intravenous ampicillin (ABPC) was added to cover enterococcus infection, empirically. The follow-up blood culture performed on the same day was found to be negative later. In our case, KD was unresponsive to IVIG in spite of proper antibiotic treatment for IPD, and KD was well responsive to PSL instead. Furthermore, when once induced, KD requires specific treatment for itself, even if the triggering infection such as IPD as in our case is controlled by proper antibiotic therapy. Kawasaki disease associated with pneumococcal infection. Impact of D-dimer on the resistance to intravenous immunoglobulin therapy in Kawasaki disease GSL
cord-261222-762nqkbg	2020	
cord-262945-zfcz0hpd	2020	
cord-263763-a8wgvgz2	2020	Here, we present our approach to a 54-year-old male patient who had coronary artery bypass (CABG) surgery diagnosed as high probability coronavirus disease 2019 (COVID-19) in early postoperative period. We aimed to present our approach to high probability COVID-19 pneumonia which developed on early postoperative period in our patient after coronary artery bypass grafting (CABG) operation, which was not reported in the literature before. After consultations applied by chest physicians and infectious disease departments of our hospital, COVID-19 was evaluated as a high probability due to the laboratory tests, radiological findings, and clinical course. Having considered our patient as high risk, without waiting for the RT-PCR result, we started the specific treatment for COVID-19 immediately, by evaluating clinical, laboratory, and radiology findings. Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1024 cases
cord-265293-l9omunq4	2020	title: Smell and Taste Disorders in COVID-19 Patients: Objective Testing and Magnetic Resonance Imaging in Five Cases Those with objectifiable alteration in taste or smell were subjected to MRI with contrast agent to investigate possible involvement of the central nervous system. We encourage medical professionals to conduct specialized examinations and MRIs in the acute stage of disease, which guarantees an optimum patient care. The study was conducted on five patients reporting impairment of taste and smell with confirmed SARS-CoV-2 infection in East Tyrol. In case objective testing revealed alterations in taste or smell, patients were subjected to MRI in a timely manner. Three weeks after the first olfactory and gustatory examination, a follow-up testing was conducted with the three patients who also had a second MRI. The first MRI images showed slight alterations in one patient, which could be associated with a SARS-CoV-2 infection. Magnetic resonance imaging alteration of the brain in a patient with coronavirus disease 2019 (COVID-19) and anosmia
cord-268617-1t7yaoct	2020	
cord-269425-e9iyso7n	2020	A systematic review was done to analyze the clinical profile and outcomes in a total of 45 cases of new-onset ITP in COVID-19 patients described in literature until date. Diagnosis of ITP in patients with moderate-to-severe COVID-19 poses a major diagnostic as well as therapeutic challenge to clinicians owing to presence of multiple concomitant conditions including HLH, DIC, sepsis, antibiotic use, heparin prophylaxis, and thromboembolic events. The following data were extracted from the included studies: age of the patient at presentation, gender, COVID-19 illness severity, comorbidities, medication use, nadir platelet count, onset of COVID-19 symptoms to diagnosis of ITP, bleeding manifestations of ITP, time to recovery from start of treatment, and clinical outcomes. Bone marrow study in these few selected cases of ITP would reveal low number of megakaryocytes, as seen in one patient of this review, who presented with severe thrombocytopenia (count 2 × 10 9 /μL) [7] .
cord-270645-tzctvs9q	2020	This study analyzed the correlation between the increment of the API (Air Pollution Index) and the rate of fatality due to SARS across 5 regions in China. In 2017, Ciencewicki and Jaspers conducted an epidemiological analysis regarding air pollution and respiratory viral infections which noted positive correlation between the high level of particulate matter (PM) in some urban areas and mortality due to cardiovascular and respiratory conditions. A recent study from the SIMA (Società Italiana di Medicina Ambientale) reported that the specificity of the high spread of the contagious virus in some areas of Northern Italy is likely to be linked to air pollution conditions. The above studies show that air pollutants, such as particulate matter, nitrogen dioxide, and carbon monoxide, are most likely direct to facilitate the longevity of virus particles in favorable climate conditions. Air pollution and case fatality of SARS in the People''s Republic of China: an ecologic study
cord-273459-3686wv7v	2020	
cord-273829-t5cuop5c	2020	Therefore, the COVID-19 pandemic control and filiation evaluation with the rRT-PCR test may produce false negative results. Patient with positive Covid-19 IgM Rapid Test performed on May 19, 2020, was subjected to the rRT-PCR test, repeated twice on the 19th of May which also resulted in positive. The nucleic acid test functions as the gold standard method for confirming the SARS-COV-2 infection; however, some recent studies have detected false negative results of real-time reverse transcriptase polymerase chain reaction (rRT-PCR) [4] . Similar to our case, there are case reports of reverse transcription-polymerase chain reaction (RT-PCR) test initially false negative and later positive in the literature [11] . Therefore, it can be argued that COVID-19 pandemic control and filiation evaluation with the rRT-PCR test may produce false negative results. A case report of COVID-19 with false negative RT-PCR test: necessity of chest CT
cord-276132-tv5y1eqc	2020	The COVID-19 pandemic has imposed a critical challenge to the current oncology care and practices including late diagnoses, delayed anti-cancer treatment, and static clinical trials. Delaying anti-cancer treatment in the ongoing pandemic cannot be recommended as a sensible choice to reduce the associated infection risk in patients. The American Society of Clinical Oncology (ASCO) recommends that in cancer patients diagnosed with the infection, the immunosuppressive therapies should be withheld until the symptoms resolve like complete remission of fever without use of antipyretics along with a negative COVID-19 test. Nevertheless, contact limitation and physical distancing guidelines continue to be an important part of the cancer treatment strategies during the pandemic in order to protect the patients, health-care personnel and non-COVID-19 patients being treated in the same organization. A practical approach to the management of cancer patients during the novel coronavirus disease 2019 (COVID-19) pandemic: an international collaborative group Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan
cord-284545-vn60yd46	2020	
cord-284734-qioy7eso	2020	According to recent observations about different modalities in treatment of patients infected with COVID-19, plasmapheresis and intravenous immunoglobulin (IVIg) have been reported to be an effective empirical therapeutic option to control the infection. According to the medical experiences in the treatment of patients infected with other members of coronavirus family such as SARS-CoV and MERS-CoV, plasmapheresis and intravenous immunoglobulin (IVIg) have been reported to be an effective empirical therapeutic option to control the infection [1] [2] [3] [4] [5] [6] [7] . As the world confronting a pandemic due to SARS-CoV-2, immunoglobulin replacement therapy (IVIG) could be an ideal option for prevention and treatment of COVID-19 disease. According to the reports, China has used immunoglobulin replacement therapy on several COVID-19 patients during the outbreak of this novel coronavirus which showed promising results [46] . The use of convalescent plasma therapy and remdesivir in the successful management of a critically ill obstetric patient with novel coronavirus 2019 infection: a case report.
cord-284785-mkjogy6h	2020	The patient''s medical history included moderate cognitive impairment, atrial fibrillation under oral anticoagulation (warfarin 2.5 mg and 3.75 mg on alternate days, showing stable PT-INR values since October 2018), and arterial hypertension. On April 20, blood analyses revealed hemoglobin 117 g/l, PT-INR 2.15, and a slight alteration of liver function with AST 55 U/l (normal range: 5-32). The temporal relationship between COVID-19 onset and PT-INR elevation in a patient whose PT-INR values were stable in the 18 months before the hospitalization supports the hypothesis that this infection may impact on the coagulative pattern not only pro-thrombotically [4, 5] but also by increasing hemorrhagic risk. This confirms that special attention should be paid to COVID-19 patients under long-term anticoagulation with vitamin K antagonist and a shift to heparin treatment until illness resolution may be a safe option in these individuals [7] .
cord-285748-us5do6c2	2020	Currently, the diagnosis and treatment of SARS-CoV-2 infection in patients with chronic kidney disease (CKD) are still unclear. Here, we review the recent findings of characteristics of COVID-19 in CKD patients and highlight the possible mechanisms of kidney injury caused by SARS-CoV-2 infection. Controversial results also exist like another study [18] indicating that SARS-CoV-2 infection was not found significantly correlated with incremental acute renal injury or aggravate chronic kidney failure in the COVID-19 patients. Therefore, SARS-CoV-2 infection in kidney transplant patients from this study showed that such cases may be severe enough requiring intensive care admission and these patients are in high risk of disease progression and death. Another study based on single-cell analysis by Lin and colleagues [28] also found that ACE2 was enriched in proximal tubular cells which may indicate that the kidney is more susceptible to SARS-CoV-2 infection.
cord-288732-k763ejqb	2020	More recently, the American Brachytherapy Society published some clarifications in this regard and international expert consensus recommendations of radiation therapy for gynecologic malignancies during the COVID-19 pandemic were published (https://www.americanbrachytherapy.org/about-abs/abs-news/abs-statement-on-coronavirus/, Gynecol Oncol 15, 2020). In the majority of cases, the treatment is based on EBRT (exclusive in early stages and with concurrent chemotherapy in locally advanced stages), followed by intracavitary brachytherapy (ICBT) which constitutes a cornerstone in its management [4] . For patients over 70 years of age or with significant comorbidities (chronic respiratory or cardiac pathology, immunosuppression, etc.) who have small tumors or responding well to external beam radiotherapy (EBRT), a more shortened schedule of 9 Gy per fraction in 2 fractions at 1 week apart may be considered. Efficacy and toxicity of concomitant cisplatin with external beam pelvic radiotherapy and two high-dose-rate brachytherapy insertions for the treatment of locally advanced cervical cancer
cord-289115-bntcn0m6	2020	
cord-292997-xbomgwzx	2020	
cord-295041-5vpawtef	2020	Numerous clinical studies have reported neurological symptoms in COVID-19 patients since the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), apart from the atypical signs of pneumonia. Angiotensin-converting enzyme-2 (ACE-2), a potential receptor for SARS-CoV-2 entry, is expressed on various brain cells and cerebral parts, i.e., subfornical organ, paraventricular nucleus, nucleus of the tractus solitarius, and rostral ventrolateral medulla, as well as in non-cardiovascular areas such as the motor cortex and raphe. The resident CNS cells like astrocytes and microglia also express ACE-2, thus highlighting the vulnerability of the nervous system to SARS-CoV-2 infection. Furthermore, the presence of SARS-CoV-2 in cerebrospinal fluid (CSF) of COVID-19 patients is confirmed through genome sequencing [4] ; however, experimental evidence is needed to validate virusmediated neurological damage. Furthermore, the interaction of SARS-CoV-2 and ACE-2-expressing neuronal/glial cells may facilitate virus entry into the nervous system through different routes.
cord-295500-j84v1k1o	2020	
cord-298980-yt52bgc7	2020	
cord-300320-07tdrd4w	2020	Medications assessed included lopinavir/ritonavir, arbidol, hydroxychloroquine, tocilizumab, favipiravir, heparin, and dexamethasone. Review of literature showed no significant clinical improvement with lopinavir/ritonavir, arbidol, hydroxychloroquine, or remdesivir. Medical therapies investigated included lopinavir/ritonavir, arbidol, hydroxychloroquine, remdesivir, favipiravir, heparin, glucocorticoids, interferon, ivermectin, and convalescent plasma. Key words included COVID-19, SARS-CoV2, randomized, This article is part of the Topical Collection on Covid-19 controlled, human, retrospective, prospective, trial, chloroquine, hydroxychloroquine, lopinavir, ritonavir, arbidol, umifenovir, tocilizumab, favipiravir, steroids, dexamethasone, glucocorticoids, interferon, ivermectin, remdesivir, azithromycin, heparin, and low-molecular weight heparin. Lopinavir/ritonavir, arbidol, hydroxychloroquine, favipiravir, remdesivir, and heparin are medications that have been tested in human controlled trials for COVID-19 treatment. In human trials, arbidol shows no significant positive-negative conversion rate or recovery time compared to standard therapy or lopinavir/ritonavir [4, 9] . Combining T, treatment group (remdesivir); C, control group all the hydroxychloroquine human trials showed no benefit with reducing COVID-19 viral shedding time.
cord-300866-cso6l6ze	2020	
cord-303731-yrlzxtbw	2020	
cord-303959-e1654g5j	2020	
cord-310084-taaz6mhs	2020	
cord-312730-4ejjmab4	2020	The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started with the detection of an increasing number of pneumonia cases of unknown origin in Wuhan, China, since December 2019. In response to the rapidly growing number of confirmed cases and deaths, some measures taken by the Chinese authorities include the quarantine of millions of its citizens with the unprecedented lockdown of many cities, in an attempt to contain the virus and slow down the spread of the disease [3] . One study in China reported a young 22-year-old male who spread SARS-CoV-2 infection to his contacts (1 relative and 6 classmates, all of which were youngsters from 16 to 23 years) just after a few-hour contact during the incubation period, when he was totally asymptomatic [18] , suggesting that the disease is highly infectious during the incubation period.
cord-317956-srbualjc	2020	The aim of this study was to compare age and comorbidities between women and men who died from COVID-19. We used a multivariable logistic regression model to identify independently significant variables associated with gender in patients who died from COVID-19. In the multivariable model, cardiovascular comorbidities were not significantly different between women and men. This study demonstrates that women who died of COVID-19 showed a similar cardiovascular disease profile as men. The present study was designed to compare age and comorbidities between women and men who died from COVID-19. Univariate analysis compared age and comorbidities between men and women who died from COVID-19. This study demonstrates that in patients who died from COVID-19, no significant difference was noted between cardiac morbidity and gender. Our study is limited to an assessment of gender differences among patients who have died from COVID-19 without considering the comorbidity rate of men versus women in the general population.
cord-318542-785hnh19	2020	
cord-320612-vam0bli3	2020	Here, we report a large nosocomial outbreak of SARS-CoV-2 that occurred at a satellite hospital of the University Hospital Aachen, Germany, with 26 patients and 21 healthcare workers infected. Considering the numerous COVID-19 cases among patients and HCW, a hospital-wide screening was initiated on April 8 for all remaining SARS-CoV-2-negative patients and entire hospital staff. On the other hand, we analyzed the first cases among hospital staff, starting with the potential index nurse tested positive for SARS-CoV-2 on the 6th of April. By the time the outbreak emerged, the hospital policy already comprised preemptive infection control measures in order to prevent intrahospital spread of SARS-CoV-2. The second route of transmission addressed by our measures was infected HCW, who potentially spread SARS-CoV-2 to patients as well as to their co-workers. In the post-outbreak period, we have continued to screen all patients on their day of admission and all geriatric inpatients once weekly for SARS-CoV-2 in order to detect new cases timely.
cord-322596-vfmzk2el	2020	
cord-323368-cf5axwcb	2020	Bergamo province was one of the hardest hit regions by the novel SARS-CoV-2 virus. Although many hypotheses have been formulated to explain the rapid outbreak of COVID-19 in Lombardy, none have yet considered the specific conditions that characterized the Bergamo hinterland. In recent months, several hypotheses have been offered to explain the rapid spread of the virus in Bergamo province and Lombardy, but all of them are focused on what happened in the hospitals (Codogno, Alzano Lombardo, and other emergency departments across the territory) involved in the SARS-CoV-2 epidemic. In particular, the management of two patients admitted in the Alzano Lombardo Hospital on the 23rd of February was thought to be critical for the epidemic outbreak. During the last week of February and first week of March, many events could be implied in the spread of SARS-CoV-2.
cord-329447-kjeqs6zh	2020	A large comprehensive gymnasium was converted into Wuchang Fangcang Shelter Hospital in order to provide adequate medical beds and appropriate care for the confirmed patients with mild to moderate symptoms. Since more than 80% of COVID-19 patients were mild or moderate types [4] [5] [6] , a novel public health measure, Fangcang Shelter Hospitals, was conceived [7] . During this major public health emergency, pharmacists, as a member of the medical team, have been responsible for providing professional and superior pharmaceutical services. Relying on the 5G network and medical information systems, the team of pharmacists accomplished pharmaceutical services smoothly, helping to reduce the risk of occupational exposure in the Shelter Hospital. In the pharmaceutical services provided at Wuchang Fangcang Shelter Hospital, ACE-I and ARBs were not recommended, but now, the latest joint viewpoint from three U.S. heart groups states that patients with COVID-19 should take ACE inhibitors and ARBs [14] .
cord-330690-cupy89gl	2020	During phase 1 (national lockdown period, March 9th-May 3rd, 2020) the Italian Ministry of Health recommended to avoid direct access to the emergency department (ED) in case of fever and/or cough or other respiratory symptoms, favoring home care or phone consultation for ill patients without compromised general conditions [10] . The aims of this study were to (1) evaluate the impact of COVID-19 pandemic on the activity of a secondary care Italian Pediatric Unit assessing, in particular, the characteristics of pediatric ED consultations performed in 2020 before and after the beginning of lockdown; (2) evaluate the prevalence of SARS-CoV-2 infection in children and adolescents referred to ED; and (3) compare pediatric ED activity during the same period of 2019 and 2020.
cord-335095-epsi5qq7	2020	Moreover, the smooth curve fitting graph reflected that the severity of COVID-19 was positively correlated with both age and CRP levels (all P value < 0.05). But the studies exploring the relationship between age, CRP levels, and the severity of COVID-19, especially by the means of smooth curve fitting, are lacking. Thus, we describe the clinical characteristics as well as laboratory findings of COVID-19 patients residing in Xiaogan City, so as to have an insight regarding the prevention as well as treatment of COVID-19, and simultaneously explore the relationship between age, CRP levels, and the severity of COVID-19, thereby exploring the indicators for predicting the severity of COVID-19. Compared with the initial COVID-19 patients observed in Wuhan, in terms of disease symptoms and severity, the patients from Xiaogan City, in our study, were relatively moderate, but we could not neglect asymptomatic or mild patients.
cord-336689-z3ayolzb	2020	We searched relevant literature in PubMed, Scopus, and Google Scholar using specific keywords, e.g., "COVID-19 pandemic," "preclinical medical education," "online learning," "remote learning," "challenges," and "opportunities." The pandemic has posed several challenges to premedical education (e.g., suspension of face-to-face teaching, lack of cadaveric dissections, and practical/laboratory sessions) but has provided many opportunities as well, such as the incorporation of online learning in the curriculum and upskilling and reskilling in new technologies. New strategies are emerging in the preclinical phase that integrates technology to make learning effective and appealing to students, [7] [8] [9] , making them more relevant and applicable for remote learning during the current COVID-19 pandemic. [40] also warned: "The COVID-19 pandemic will not be the last major infectious disease that puts learners at risk." However, many medical schools have successfully transitioned their teaching and learning environment to emergency remote learning, having monitored and examined student and staff readiness, and completed online formative and summative exams both in preclinical and clinical years.
cord-336790-29im4gxw	2020	
cord-337026-osgi06o4	2020	Given the uprising number of publications and case reports of COVID-19 patients showing conjunctivitis [61, 62] and the history of other coronaviruses that are found in tears, we have to consider the possibility of a separate, alternative viral mechanism through which the virus can enter the patient''s organism through epithelial cells of the eye [63] . The growing evidence on COVID-19 and its ocular implications and manifestations, in both animals and humans, is covered by many interesting reviews, all published 5 to 6 months after the novel coronavirus'' outbreak [64] [65] [66] [67] [68] , something that reveals the need to understand the virus from different perspectiveswhich at first may have seemed secondary in priority-in order to be able to reach a treatment.
cord-338544-eph89g47	2020	
cord-339332-6lml531t	2020	The direct mode includes (1) transmission via aerosols formed via surgical and dental procedures and/or in the form of respiratory droplet nuclei; (2) other body fluids and secretions, for example, feces, saliva, urine, semen, and tears; and (3) mother-to-child. The direct mode includes (1) transmission via aerosols formed via surgical and dental procedures and/or in the form of respiratory droplet nuclei; (2) other body fluids and secretions, for example, feces, saliva, urine, semen, and tears; and (3) mother-to-child. The goal of this paper is to briefly review how SARS-CoV-2 is shown to transmit via various modes and propose measures to reduce the risk of spread within the population and operating personnel. Letter: the risk of COVID-19 infection during neurosurgical procedures: a review of severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) modes of transmission and proposed neurosurgery-specific measures for mitigation
cord-340305-jtvn9tlm	2020	
cord-341987-lsvifqyo	2020	
cord-344217-kci4uw7u	2020	Coronavirus disease 2019 (COVID-19), an ongoing global health emergency, is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronaviruses (CoVs) have emerged as a major public health concern having caused three zoonotic outbreaks; severe acute respiratory syndrome-CoV (SARS-CoV) in 2002–2003, Middle East respiratory syndrome-CoV (MERS-CoV) in 2012, and currently this devastating COVID-19. Beta coronaviruses are a subgroup of the coronavirus family, large enveloped positive-sense singlestranded RNA (+ssRNA) viruses able to infect a wide variety of mammals and avian species, causing mainly respiratory or enteric diseases [2] . The disease caused by SARS-CoV-2 has been named COVID-19, a highly transmittable and pathogenic respiratory infection, which has become a public health emergency of international concern as no clinically approved antiviral drug or vaccine is available-though few broad spectrum antiviral drugs and drug combinations in clinical trials have resulted in clinical recovery [23] [24] [25] [26] [27] .
cord-347926-63w578b2	2020	We recorded patients'' epidemiological, clinical features, and follow-up data after discharging in order to improve the awareness and treatment of children with COVID-19. Since December 2019, multiple patients of pneumonia infected with the emergence of severe acute respiratory syndrome coronavirus 2 disease (COVID-19) had been detected in Wuhan city, China [1] . So, analysis of the clinical characteristics, epidemiological characteristics, and follow-up results after discharge of pediatric patients with confirmed COVID-19 in this area was aimed at improving the awareness and treatment of children with COVID-19. Diagnosis and discharge standards were performed according to the content of the "Diagnosis and treatment guidelines for 2019 novel coronavirus pneumonia (Trial Version 7) (In Chinese) [3] ." We observed and recorded the patient''s epidemiological characteristics, clinical manifestations, laboratory tests, radiography, treatment methods, and transfer return. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study
cord-348121-c7jq240j	2020	
cord-351531-wo1ggmmn	2020	
cord-352642-u513wnu1	2020	After reviewing this case in light of current evidence and debates surrounding SARS-CoV-2 RT-PCR results, we hypothesize that patients on corticosteroids may have particular viral shedding dynamics and should prompt a more conservative approach in regard to isolation discontinuation and monitoring. Since the identification of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the cause of the disease which was later named COVID-19, and as it progressed to the current worldwide pandemic, much investigation has been made regarding its clinical presentation, transmission route, and immunity. This could point either to a reactivation of the disease in a patient who first presented as asymptomatic or to a long incubation period (18 days from risk contact until developing symptoms, with a CT performed 3 days prior to the onset of symptoms showing an evolving disease, which is consistent with previous studies reporting typical radiological findings of COVID-19 in asymptomatic or presymptomatic patients [2] ).