id	sid	tid	token	lemma	pos
cord-315781-dejh8q22	1	1	key	key	NN
cord-315781-dejh8q22	1	2	:	:	:
cord-315781-dejh8q22	2	1	cord-315781-dejh8q22	cord-315781-dejh8q22	JJ
cord-315781-dejh8q22	2	2	authors	author	NNS
cord-315781-dejh8q22	2	3	:	:	:
cord-315781-dejh8q22	2	4	Konishi	Konishi	NNP
cord-315781-dejh8q22	2	5	,	,	,
cord-315781-dejh8q22	2	6	Tomokazu	Tomokazu	NNP
cord-315781-dejh8q22	2	7	title	title	NN
cord-315781-dejh8q22	2	8	:	:	:
cord-315781-dejh8q22	2	9	Re	re	NN
cord-315781-dejh8q22	2	10	-	-	NN
cord-315781-dejh8q22	2	11	evaluation	evaluation	NN
cord-315781-dejh8q22	2	12	of	of	IN
cord-315781-dejh8q22	2	13	the	the	DT
cord-315781-dejh8q22	2	14	evolution	evolution	NN
cord-315781-dejh8q22	2	15	of	of	IN
cord-315781-dejh8q22	2	16	influenza	influenza	NN
cord-315781-dejh8q22	2	17	H1	h1	NN
cord-315781-dejh8q22	2	18	viruses	virus	NNS
cord-315781-dejh8q22	2	19	using	use	VBG
cord-315781-dejh8q22	2	20	direct	direct	JJ
cord-315781-dejh8q22	2	21	PCA	PCA	NNP
cord-315781-dejh8q22	2	22	date	date	NN
cord-315781-dejh8q22	2	23	:	:	:
cord-315781-dejh8q22	2	24	2019	2019	CD
cord-315781-dejh8q22	2	25	-	-	HYPH
cord-315781-dejh8q22	2	26	12	12	CD
cord-315781-dejh8q22	2	27	-	-	SYM
cord-315781-dejh8q22	2	28	17	17	CD
cord-315781-dejh8q22	2	29	journal	journal	NN
cord-315781-dejh8q22	2	30	:	:	:
cord-315781-dejh8q22	3	1	Sci	Sci	NNP
cord-315781-dejh8q22	3	2	Rep	Rep	NNP
cord-315781-dejh8q22	3	3	DOI	DOI	NNP
cord-315781-dejh8q22	3	4	:	:	:
cord-315781-dejh8q22	4	1	10.1038	10.1038	CD
cord-315781-dejh8q22	4	2	/	/	SYM
cord-315781-dejh8q22	4	3	s41598	s41598	CD
cord-315781-dejh8q22	4	4	-	-	HYPH
cord-315781-dejh8q22	4	5	019	019	CD
cord-315781-dejh8q22	4	6	-	-	HYPH
cord-315781-dejh8q22	4	7	55254-z	55254-z	CD
cord-315781-dejh8q22	4	8	sha	sha	NNP
cord-315781-dejh8q22	4	9	:	:	:
cord-315781-dejh8q22	4	10	275cb246ac9ec33ec4e7fa1042caab6016c0e0e5	275cb246ac9ec33ec4e7fa1042caab6016c0e0e5	CD
cord-315781-dejh8q22	4	11	doc_id	doc_id	CD
cord-315781-dejh8q22	4	12	:	:	:
cord-315781-dejh8q22	4	13	315781	315781	CD
cord-315781-dejh8q22	4	14	cord_uid	cord_uid	NN
cord-315781-dejh8q22	4	15	:	:	:
cord-315781-dejh8q22	5	1	dejh8q22	dejh8q22	NNP
cord-315781-dejh8q22	5	2	The	the	DT
cord-315781-dejh8q22	5	3	history	history	NN
cord-315781-dejh8q22	5	4	of	of	IN
cord-315781-dejh8q22	5	5	influenza	influenza	NN
cord-315781-dejh8q22	5	6	H1	h1	NN
cord-315781-dejh8q22	5	7	virus	virus	NN
cord-315781-dejh8q22	5	8	was	be	VBD
cord-315781-dejh8q22	5	9	re	re	VBN
cord-315781-dejh8q22	5	10	-	-	VBN
cord-315781-dejh8q22	5	11	evaluated	evaluate	VBN
cord-315781-dejh8q22	5	12	by	by	IN
cord-315781-dejh8q22	5	13	applying	apply	VBG
cord-315781-dejh8q22	5	14	a	a	DT
cord-315781-dejh8q22	5	15	new	new	JJ
cord-315781-dejh8q22	5	16	methodology	methodology	NN
cord-315781-dejh8q22	5	17	to	to	IN
cord-315781-dejh8q22	5	18	sequencing	sequence	VBG
cord-315781-dejh8q22	5	19	data	datum	NNS
cord-315781-dejh8q22	5	20	;	;	:
cord-315781-dejh8q22	5	21	this	this	DT
cord-315781-dejh8q22	5	22	objective	objective	JJ
cord-315781-dejh8q22	5	23	method	method	NN
cord-315781-dejh8q22	5	24	enables	enable	VBZ
cord-315781-dejh8q22	5	25	comparisons	comparison	NNS
cord-315781-dejh8q22	5	26	among	among	IN
cord-315781-dejh8q22	5	27	viral	viral	JJ
cord-315781-dejh8q22	5	28	types	type	NNS
cord-315781-dejh8q22	5	29	.	.	.
cord-315781-dejh8q22	6	1	The	the	DT
cord-315781-dejh8q22	6	2	approach	approach	NN
cord-315781-dejh8q22	6	3	led	lead	VBD
cord-315781-dejh8q22	6	4	to	to	IN
cord-315781-dejh8q22	6	5	the	the	DT
cord-315781-dejh8q22	6	6	segregation	segregation	NN
cord-315781-dejh8q22	6	7	of	of	IN
cord-315781-dejh8q22	6	8	all	all	DT
cord-315781-dejh8q22	6	9	segments	segment	NNS
cord-315781-dejh8q22	6	10	of	of	IN
cord-315781-dejh8q22	6	11	swine	swine	NN
cord-315781-dejh8q22	6	12	and	and	CC
cord-315781-dejh8q22	6	13	human	human	JJ
cord-315781-dejh8q22	6	14	viruses	virus	NNS
cord-315781-dejh8q22	6	15	into	into	IN
cord-315781-dejh8q22	6	16	three	three	CD
cord-315781-dejh8q22	6	17	distinct	distinct	JJ
cord-315781-dejh8q22	6	18	groups	group	NNS
cord-315781-dejh8q22	6	19	:	:	:
cord-315781-dejh8q22	6	20	two	two	CD
cord-315781-dejh8q22	6	21	of	of	IN
cord-315781-dejh8q22	6	22	them	-PRON-	PRP
cord-315781-dejh8q22	6	23	included	include	VBD
cord-315781-dejh8q22	6	24	the	the	DT
cord-315781-dejh8q22	6	25	pandemic	pandemic	NN
cord-315781-dejh8q22	6	26	1977	1977	CD
cord-315781-dejh8q22	6	27	and	and	CC
cord-315781-dejh8q22	6	28	2009	2009	CD
cord-315781-dejh8q22	6	29	human	human	JJ
cord-315781-dejh8q22	6	30	viruses	virus	NNS
cord-315781-dejh8q22	6	31	,	,	,
cord-315781-dejh8q22	6	32	and	and	CC
cord-315781-dejh8q22	6	33	the	the	DT
cord-315781-dejh8q22	6	34	remaining	remain	VBG
cord-315781-dejh8q22	6	35	group	group	NN
cord-315781-dejh8q22	6	36	may	may	MD
cord-315781-dejh8q22	6	37	be	be	VB
cord-315781-dejh8q22	6	38	new	new	JJ
cord-315781-dejh8q22	6	39	in	in	IN
cord-315781-dejh8q22	6	40	humans	human	NNS
cord-315781-dejh8q22	6	41	.	.	.
cord-315781-dejh8q22	7	1	These	these	DT
cord-315781-dejh8q22	7	2	three	three	CD
cord-315781-dejh8q22	7	3	groups	group	NNS
cord-315781-dejh8q22	7	4	might	may	MD
cord-315781-dejh8q22	7	5	have	have	VB
cord-315781-dejh8q22	7	6	originated	originate	VBN
cord-315781-dejh8q22	7	7	from	from	IN
cord-315781-dejh8q22	7	8	avian	avian	JJ
cord-315781-dejh8q22	7	9	viruses	virus	NNS
cord-315781-dejh8q22	7	10	and	and	CC
cord-315781-dejh8q22	7	11	drifted	drift	VBD
cord-315781-dejh8q22	7	12	out	out	RP
cord-315781-dejh8q22	7	13	independently	independently	RB
cord-315781-dejh8q22	7	14	.	.	.
cord-315781-dejh8q22	8	1	Genome	genome	NN
cord-315781-dejh8q22	8	2	shifts	shift	NNS
cord-315781-dejh8q22	8	3	occurred	occur	VBD
cord-315781-dejh8q22	8	4	occasionally	occasionally	RB
cord-315781-dejh8q22	8	5	among	among	IN
cord-315781-dejh8q22	8	6	swine	swine	NN
cord-315781-dejh8q22	8	7	viruses	virus	NNS
cord-315781-dejh8q22	8	8	;	;	:
cord-315781-dejh8q22	8	9	however	however	RB
cord-315781-dejh8q22	8	10	,	,	,
cord-315781-dejh8q22	8	11	distances	distance	NNS
cord-315781-dejh8q22	8	12	between	between	IN
cord-315781-dejh8q22	8	13	avian	avian	JJ
cord-315781-dejh8q22	8	14	and	and	CC
cord-315781-dejh8q22	8	15	swine	swine	NN
cord-315781-dejh8q22	8	16	/	/	SYM
cord-315781-dejh8q22	8	17	human	human	NN
cord-315781-dejh8q22	8	18	viruses	virus	NNS
cord-315781-dejh8q22	8	19	negated	negate	VBD
cord-315781-dejh8q22	8	20	the	the	DT
cord-315781-dejh8q22	8	21	existence	existence	NN
cord-315781-dejh8q22	8	22	of	of	IN
cord-315781-dejh8q22	8	23	direct	direct	JJ
cord-315781-dejh8q22	8	24	shifts	shift	NNS
cord-315781-dejh8q22	8	25	from	from	IN
cord-315781-dejh8q22	8	26	avian	avian	JJ
cord-315781-dejh8q22	8	27	viruses	virus	NNS
cord-315781-dejh8q22	8	28	.	.	.
cord-315781-dejh8q22	9	1	In	in	IN
cord-315781-dejh8q22	9	2	humans	human	NNS
cord-315781-dejh8q22	9	3	,	,	,
cord-315781-dejh8q22	9	4	only	only	RB
cord-315781-dejh8q22	9	5	one	one	CD
cord-315781-dejh8q22	9	6	or	or	CC
cord-315781-dejh8q22	9	7	two	two	CD
cord-315781-dejh8q22	9	8	viruses	virus	NNS
cord-315781-dejh8q22	9	9	appeared	appear	VBD
cord-315781-dejh8q22	9	10	each	each	DT
cord-315781-dejh8q22	9	11	year	year	NN
cord-315781-dejh8q22	9	12	,	,	,
cord-315781-dejh8q22	9	13	which	which	WDT
cord-315781-dejh8q22	9	14	suggests	suggest	VBZ
cord-315781-dejh8q22	9	15	the	the	DT
cord-315781-dejh8q22	9	16	presence	presence	NN
cord-315781-dejh8q22	9	17	of	of	IN
cord-315781-dejh8q22	9	18	competition	competition	NN
cord-315781-dejh8q22	9	19	among	among	IN
cord-315781-dejh8q22	9	20	viruses	virus	NNS
cord-315781-dejh8q22	9	21	that	that	WDT
cord-315781-dejh8q22	9	22	migrated	migrate	VBD
cord-315781-dejh8q22	9	23	freely	freely	RB
cord-315781-dejh8q22	9	24	.	.	.
cord-315781-dejh8q22	10	1	All	all	DT
cord-315781-dejh8q22	10	2	segments	segment	NNS
cord-315781-dejh8q22	10	3	drifted	drift	VBD
cord-315781-dejh8q22	10	4	continuously	continuously	RB
cord-315781-dejh8q22	10	5	under	under	IN
cord-315781-dejh8q22	10	6	certain	certain	JJ
cord-315781-dejh8q22	10	7	rules	rule	NNS
cord-315781-dejh8q22	10	8	and	and	CC
cord-315781-dejh8q22	10	9	constant	constant	JJ
cord-315781-dejh8q22	10	10	velocity	velocity	NN
cord-315781-dejh8q22	10	11	.	.	.
cord-315781-dejh8q22	11	1	Viruses	virus	NNS
cord-315781-dejh8q22	11	2	that	that	WDT
cord-315781-dejh8q22	11	3	had	have	VBD
cord-315781-dejh8q22	11	4	caused	cause	VBN
cord-315781-dejh8q22	11	5	an	an	DT
cord-315781-dejh8q22	11	6	outbreak	outbreak	NN
cord-315781-dejh8q22	11	7	did	do	VBD
cord-315781-dejh8q22	11	8	not	not	RB
cord-315781-dejh8q22	11	9	appear	appear	VB
cord-315781-dejh8q22	11	10	again	again	RB
cord-315781-dejh8q22	11	11	over	over	IN
cord-315781-dejh8q22	11	12	subsequent	subsequent	JJ
cord-315781-dejh8q22	11	13	decades	decade	NNS
cord-315781-dejh8q22	11	14	,	,	,
cord-315781-dejh8q22	11	15	which	which	WDT
cord-315781-dejh8q22	11	16	may	may	MD
cord-315781-dejh8q22	11	17	mean	mean	VB
cord-315781-dejh8q22	11	18	populations	population	NNS
cord-315781-dejh8q22	11	19	had	have	VBD
cord-315781-dejh8q22	11	20	become	become	VBN
cord-315781-dejh8q22	11	21	immune	immune	JJ
cord-315781-dejh8q22	11	22	to	to	IN
cord-315781-dejh8q22	11	23	such	such	JJ
cord-315781-dejh8q22	11	24	viruses	virus	NNS
cord-315781-dejh8q22	11	25	.	.	.
cord-315781-dejh8q22	12	1	In	in	IN
cord-315781-dejh8q22	12	2	contrast	contrast	NN
cord-315781-dejh8q22	12	3	,	,	,
cord-315781-dejh8q22	12	4	the	the	DT
cord-315781-dejh8q22	12	5	viruses	virus	NNS
cord-315781-dejh8q22	12	6	in	in	IN
cord-315781-dejh8q22	12	7	livestock	livestock	NN
cord-315781-dejh8q22	12	8	were	be	VBD
cord-315781-dejh8q22	12	9	rather	rather	RB
cord-315781-dejh8q22	12	10	conserved	conserved	JJ
cord-315781-dejh8q22	12	11	and	and	CC
cord-315781-dejh8q22	12	12	maintained	maintain	VBD
cord-315781-dejh8q22	12	13	unique	unique	JJ
cord-315781-dejh8q22	12	14	strains	strain	NNS
cord-315781-dejh8q22	12	15	in	in	IN
cord-315781-dejh8q22	12	16	small	small	JJ
cord-315781-dejh8q22	12	17	,	,	,
cord-315781-dejh8q22	12	18	separate	separate	JJ
cord-315781-dejh8q22	12	19	areas	area	NNS
cord-315781-dejh8q22	12	20	.	.	.
cord-315781-dejh8q22	13	1	Such	such	JJ
cord-315781-dejh8q22	13	2	collections	collection	NNS
cord-315781-dejh8q22	13	3	of	of	IN
cord-315781-dejh8q22	13	4	swine	swine	NN
cord-315781-dejh8q22	13	5	strains	strain	NNS
cord-315781-dejh8q22	13	6	included	include	VBD
cord-315781-dejh8q22	13	7	human	human	JJ
cord-315781-dejh8q22	13	8	segments	segment	NNS
cord-315781-dejh8q22	13	9	,	,	,
cord-315781-dejh8q22	13	10	which	which	WDT
cord-315781-dejh8q22	13	11	could	could	MD
cord-315781-dejh8q22	13	12	become	become	VB
cord-315781-dejh8q22	13	13	an	an	DT
cord-315781-dejh8q22	13	14	epidemic	epidemic	NN
cord-315781-dejh8q22	13	15	in	in	IN
cord-315781-dejh8q22	13	16	the	the	DT
cord-315781-dejh8q22	13	17	future	future	NN
cord-315781-dejh8q22	13	18	.	.	.
cord-315781-dejh8q22	14	1	Russia	Russia	NNP
cord-315781-dejh8q22	14	2	viruses	virus	NNS
cord-315781-dejh8q22	14	3	,	,	,
cord-315781-dejh8q22	14	4	respectively	respectively	RB
cord-315781-dejh8q22	14	5	.	.	.
cord-315781-dejh8q22	15	1	Black	black	JJ
cord-315781-dejh8q22	15	2	,	,	,
cord-315781-dejh8q22	15	3	human	human	JJ
cord-315781-dejh8q22	15	4	;	;	,
cord-315781-dejh8q22	15	5	green	green	JJ
cord-315781-dejh8q22	15	6	,	,	,
cord-315781-dejh8q22	15	7	swine	swine	NN
cord-315781-dejh8q22	15	8	,	,	,
cord-315781-dejh8q22	15	9	and	and	CC
cord-315781-dejh8q22	15	10	blue	blue	JJ
cord-315781-dejh8q22	15	11	,	,	,
cord-315781-dejh8q22	15	12	avian	avian	JJ
cord-315781-dejh8q22	15	13	.	.	.
cord-315781-dejh8q22	16	1	The	the	DT
cord-315781-dejh8q22	16	2	orange	orange	JJ
cord-315781-dejh8q22	16	3	-	-	HYPH
cord-315781-dejh8q22	16	4	coloured	coloured	JJ
cord-315781-dejh8q22	16	5	"	"	``
cord-315781-dejh8q22	16	6	H	h	NN
cord-315781-dejh8q22	16	7	"	"	''
cord-315781-dejh8q22	16	8	in	in	IN
cord-315781-dejh8q22	16	9	the	the	DT
cord-315781-dejh8q22	16	10	M	M	NNP
cord-315781-dejh8q22	16	11	group	group	NN
cord-315781-dejh8q22	16	12	is	be	VBZ
cord-315781-dejh8q22	16	13	one	one	CD
cord-315781-dejh8q22	16	14	of	of	IN
cord-315781-dejh8q22	16	15	the	the	DT
cord-315781-dejh8q22	16	16	strains	strain	NNS
cord-315781-dejh8q22	16	17	classified	classify	VBN
cord-315781-dejh8q22	16	18	as	as	IN
cord-315781-dejh8q22	16	19	the	the	DT
cord-315781-dejh8q22	16	20	"	"	``
cord-315781-dejh8q22	16	21	triple	triple	JJ
cord-315781-dejh8q22	16	22	reassortant	reassortant	JJ
cord-315781-dejh8q22	16	23	"	"	''
cord-315781-dejh8q22	16	24	8	8	CD
cord-315781-dejh8q22	16	25	.	.	.
cord-315781-dejh8q22	17	1	The	the	DT
cord-315781-dejh8q22	17	2	H	H	NNP
cord-315781-dejh8q22	17	3	in	in	IN
cord-315781-dejh8q22	17	4	the	the	DT
cord-315781-dejh8q22	17	5	U	U	NNP
cord-315781-dejh8q22	17	6	group	group	NN
cord-315781-dejh8q22	17	7	is	be	VBZ
cord-315781-dejh8q22	17	8	the	the	DT
cord-315781-dejh8q22	17	9	human	human	JJ
cord-315781-dejh8q22	17	10	virus	virus	NN
cord-315781-dejh8q22	17	11	found	find	VBN
cord-315781-dejh8q22	17	12	in	in	IN
cord-315781-dejh8q22	17	13	Switzerland	Switzerland	NNP
cord-315781-dejh8q22	17	14	(	(	-LRB-
cord-315781-dejh8q22	17	15	NCBI	NCBI	NNP
cord-315781-dejh8q22	17	16	taxonomy	taxonomy	NN
cord-315781-dejh8q22	17	17	ID	ID	NNP
cord-315781-dejh8q22	17	18	:	:	:
cord-315781-dejh8q22	17	19	940568	940568	CD
cord-315781-dejh8q22	17	20	)	)	-RRB-
cord-315781-dejh8q22	17	21	.	.	.
cord-315781-dejh8q22	18	1	(	(	-LRB-
cord-315781-dejh8q22	18	2	Fig	Fig	NNP
cord-315781-dejh8q22	18	3	.	.	.
cord-315781-dejh8q22	18	4	S1E	s1e	NN
cord-315781-dejh8q22	18	5	)	)	-RRB-
cord-315781-dejh8q22	18	6	.	.	.
cord-315781-dejh8q22	19	1	Differences	difference	NNS
cord-315781-dejh8q22	19	2	within	within	IN
cord-315781-dejh8q22	19	3	a	a	DT
cord-315781-dejh8q22	19	4	type	type	NN
cord-315781-dejh8q22	19	5	appeared	appear	VBD
cord-315781-dejh8q22	19	6	in	in	IN
cord-315781-dejh8q22	19	7	low	low	JJ
cord-315781-dejh8q22	19	8	-	-	HYPH
cord-315781-dejh8q22	19	9	level	level	NN
cord-315781-dejh8q22	19	10	PCs	pc	NNS
cord-315781-dejh8q22	19	11	;	;	:
cord-315781-dejh8q22	19	12	however	however	RB
cord-315781-dejh8q22	19	13	,	,	,
cord-315781-dejh8q22	19	14	swine	swine	NN
cord-315781-dejh8q22	19	15	can	can	MD
cord-315781-dejh8q22	19	16	accept	accept	VB
cord-315781-dejh8q22	19	17	the	the	DT
cord-315781-dejh8q22	19	18	wide	wide	JJ
cord-315781-dejh8q22	19	19	variations	variation	NNS
cord-315781-dejh8q22	19	20	that	that	WDT
cord-315781-dejh8q22	19	21	appeared	appear	VBD
cord-315781-dejh8q22	19	22	in	in	IN
cord-315781-dejh8q22	19	23	PC1	PC1	NNP
cord-315781-dejh8q22	19	24	and	and	CC
cord-315781-dejh8q22	19	25	2	2	CD
cord-315781-dejh8q22	20	1	(	(	-LRB-
cord-315781-dejh8q22	20	2	Fig	Fig	NNP
cord-315781-dejh8q22	20	3	.	.	.
cord-315781-dejh8q22	20	4	1C	1C	NNP
cord-315781-dejh8q22	20	5	)	)	-RRB-
cord-315781-dejh8q22	20	6	.	.	.
cord-315781-dejh8q22	21	1	The	the	DT
cord-315781-dejh8q22	21	2	tendency	tendency	NN
cord-315781-dejh8q22	21	3	to	to	TO
cord-315781-dejh8q22	21	4	segregate	segregate	VB
cord-315781-dejh8q22	21	5	into	into	IN
cord-315781-dejh8q22	21	6	the	the	DT
cord-315781-dejh8q22	21	7	three	three	CD
cord-315781-dejh8q22	21	8	groups	group	NNS
cord-315781-dejh8q22	21	9	was	be	VBD
cord-315781-dejh8q22	21	10	also	also	RB
cord-315781-dejh8q22	21	11	observed	observe	VBN
cord-315781-dejh8q22	21	12	for	for	IN
cord-315781-dejh8q22	21	13	the	the	DT
cord-315781-dejh8q22	21	14	other	other	JJ
cord-315781-dejh8q22	21	15	genome	genome	NN
cord-315781-dejh8q22	21	16	segments	segment	NNS
cord-315781-dejh8q22	21	17	(	(	-LRB-
cord-315781-dejh8q22	21	18	Fig	Fig	NNP
cord-315781-dejh8q22	21	19	.	.	.
cord-315781-dejh8q22	21	20	S2	S2	NNP
cord-315781-dejh8q22	21	21	)	)	-RRB-
cord-315781-dejh8q22	21	22	;	;	:
cord-315781-dejh8q22	21	23	the	the	DT
cord-315781-dejh8q22	21	24	R	r	NN
cord-315781-dejh8q22	21	25	,	,	,
cord-315781-dejh8q22	21	26	M	M	NNP
cord-315781-dejh8q22	21	27	,	,	,
cord-315781-dejh8q22	21	28	and	and	CC
cord-315781-dejh8q22	21	29	U	U	NNP
cord-315781-dejh8q22	21	30	groups	group	NNS
cord-315781-dejh8q22	21	31	appeared	appear	VBD
cord-315781-dejh8q22	21	32	from	from	IN
cord-315781-dejh8q22	21	33	the	the	DT
cord-315781-dejh8q22	21	34	top	top	NN
cord-315781-dejh8q22	21	35	,	,	,
cord-315781-dejh8q22	21	36	clockwise	clockwise	RB
cord-315781-dejh8q22	21	37	.	.	.
cord-315781-dejh8q22	22	1	The	the	DT
cord-315781-dejh8q22	22	2	groups	group	NNS
cord-315781-dejh8q22	22	3	that	that	WDT
cord-315781-dejh8q22	22	4	include	include	VBP
cord-315781-dejh8q22	22	5	the	the	DT
cord-315781-dejh8q22	22	6	segments	segment	NNS
cord-315781-dejh8q22	22	7	of	of	IN
cord-315781-dejh8q22	22	8	the	the	DT
cord-315781-dejh8q22	22	9	two	two	CD
cord-315781-dejh8q22	22	10	pandemic	pandemic	NN
cord-315781-dejh8q22	22	11	viruses	virus	NNS
cord-315781-dejh8q22	22	12	,	,	,
cord-315781-dejh8q22	22	13	Russia	Russia	NNP
cord-315781-dejh8q22	22	14	1977	1977	CD
cord-315781-dejh8q22	22	15	and	and	CC
cord-315781-dejh8q22	22	16	Mexico	Mexico	NNP
cord-315781-dejh8q22	22	17	2009	2009	CD
cord-315781-dejh8q22	22	18	,	,	,
cord-315781-dejh8q22	22	19	are	be	VBP
cord-315781-dejh8q22	22	20	termed	term	VBN
cord-315781-dejh8q22	22	21	R	R	NNP
cord-315781-dejh8q22	22	22	and	and	CC
cord-315781-dejh8q22	22	23	M	M	NNP
cord-315781-dejh8q22	22	24	,	,	,
cord-315781-dejh8q22	22	25	respectively	respectively	RB
cord-315781-dejh8q22	22	26	,	,	,
cord-315781-dejh8q22	22	27	with	with	IN
cord-315781-dejh8q22	22	28	U	U	NNP
cord-315781-dejh8q22	22	29	being	be	VBG
cord-315781-dejh8q22	22	30	the	the	DT
cord-315781-dejh8q22	22	31	remaining	remain	VBG
cord-315781-dejh8q22	22	32	group	group	NN
cord-315781-dejh8q22	22	33	.	.	.
cord-315781-dejh8q22	23	1	As	as	IN
cord-315781-dejh8q22	23	2	the	the	DT
cord-315781-dejh8q22	23	3	distances	distance	NNS
cord-315781-dejh8q22	23	4	among	among	IN
cord-315781-dejh8q22	23	5	the	the	DT
cord-315781-dejh8q22	23	6	groups	group	NNS
cord-315781-dejh8q22	23	7	are	be	VBP
cord-315781-dejh8q22	23	8	similar	similar	JJ
cord-315781-dejh8q22	23	9	in	in	IN
cord-315781-dejh8q22	23	10	all	all	DT
cord-315781-dejh8q22	23	11	segments	segment	NNS
cord-315781-dejh8q22	23	12	,	,	,
cord-315781-dejh8q22	23	13	they	-PRON-	PRP
cord-315781-dejh8q22	23	14	were	be	VBD
cord-315781-dejh8q22	23	15	placed	place	VBN
cord-315781-dejh8q22	23	16	similarly	similarly	RB
cord-315781-dejh8q22	23	17	on	on	IN
cord-315781-dejh8q22	23	18	the	the	DT
cord-315781-dejh8q22	23	19	plots	plot	NNS
cord-315781-dejh8q22	23	20	(	(	-LRB-
cord-315781-dejh8q22	23	21	Fig	Fig	NNP
cord-315781-dejh8q22	23	22	.	.	.
cord-315781-dejh8q22	23	23	S2	S2	NNP
cord-315781-dejh8q22	23	24	)	)	-RRB-
cord-315781-dejh8q22	23	25	.	.	.
cord-315781-dejh8q22	24	1	Variations	variation	NNS
cord-315781-dejh8q22	24	2	in	in	IN
cord-315781-dejh8q22	24	3	the	the	DT
cord-315781-dejh8q22	24	4	rotation	rotation	NN
cord-315781-dejh8q22	24	5	angle	angle	NN
cord-315781-dejh8q22	24	6	of	of	IN
cord-315781-dejh8q22	24	7	the	the	DT
cord-315781-dejh8q22	24	8	triangle	triangle	NN
cord-315781-dejh8q22	24	9	were	be	VBD
cord-315781-dejh8q22	24	10	caused	cause	VBN
cord-315781-dejh8q22	24	11	by	by	IN
cord-315781-dejh8q22	24	12	differences	difference	NNS
cord-315781-dejh8q22	24	13	in	in	IN
cord-315781-dejh8q22	24	14	the	the	DT
cord-315781-dejh8q22	24	15	number	number	NN
cord-315781-dejh8q22	24	16	of	of	IN
cord-315781-dejh8q22	24	17	samples	sample	NNS
cord-315781-dejh8q22	24	18	among	among	IN
cord-315781-dejh8q22	24	19	the	the	DT
cord-315781-dejh8q22	24	20	groups	group	NNS
cord-315781-dejh8q22	24	21	.	.	.
cord-315781-dejh8q22	25	1	Fig	Fig	NNP
cord-315781-dejh8q22	25	2	.	.	.
cord-315781-dejh8q22	26	1	S2	S2	NNP
cord-315781-dejh8q22	26	2	includes	include	VBZ
cord-315781-dejh8q22	26	3	several	several	JJ
cord-315781-dejh8q22	26	4	very	very	RB
cord-315781-dejh8q22	26	5	old	old	JJ
cord-315781-dejh8q22	26	6	strains	strain	NNS
cord-315781-dejh8q22	26	7	:	:	:
cord-315781-dejh8q22	26	8	the	the	DT
cord-315781-dejh8q22	26	9	1918	1918	CD
cord-315781-dejh8q22	26	10	and	and	CC
cord-315781-dejh8q22	26	11	1943	1943	CD
cord-315781-dejh8q22	26	12	human	human	JJ
cord-315781-dejh8q22	26	13	pandemic	pandemic	NN
cord-315781-dejh8q22	26	14	strains	strain	NNS
cord-315781-dejh8q22	26	15	(	(	-LRB-
cord-315781-dejh8q22	26	16	green	green	JJ
cord-315781-dejh8q22	26	17	)	)	-RRB-
cord-315781-dejh8q22	26	18	and	and	CC
cord-315781-dejh8q22	26	19	the	the	DT
cord-315781-dejh8q22	26	20	1930	1930	CD
cord-315781-dejh8q22	26	21	swine	swine	NN
cord-315781-dejh8q22	26	22	strains	strain	NNS
cord-315781-dejh8q22	26	23	(	(	-LRB-
cord-315781-dejh8q22	26	24	grey	grey	NNP
cord-315781-dejh8q22	26	25	)	)	-RRB-
cord-315781-dejh8q22	26	26	;	;	:
cord-315781-dejh8q22	26	27	they	-PRON-	PRP
cord-315781-dejh8q22	26	28	showed	show	VBD
cord-315781-dejh8q22	26	29	a	a	DT
cord-315781-dejh8q22	26	30	tendency	tendency	NN
cord-315781-dejh8q22	26	31	to	to	TO
cord-315781-dejh8q22	26	32	be	be	VB
cord-315781-dejh8q22	26	33	located	locate	VBN
cord-315781-dejh8q22	26	34	closer	close	RBR
cord-315781-dejh8q22	26	35	to	to	IN
cord-315781-dejh8q22	26	36	the	the	DT
cord-315781-dejh8q22	26	37	origin	origin	NN
cord-315781-dejh8q22	26	38	of	of	IN
cord-315781-dejh8q22	26	39	the	the	DT
cord-315781-dejh8q22	26	40	plot	plot	NN
cord-315781-dejh8q22	26	41	.	.	.
cord-315781-dejh8q22	27	1	The	the	DT
cord-315781-dejh8q22	27	2	magnitudes	magnitude	NNS
cord-315781-dejh8q22	27	3	of	of	IN
cord-315781-dejh8q22	27	4	PCs	pc	NNS
cord-315781-dejh8q22	27	5	were	be	VBD
cord-315781-dejh8q22	27	6	similar	similar	JJ
cord-315781-dejh8q22	27	7	among	among	IN
cord-315781-dejh8q22	27	8	the	the	DT
cord-315781-dejh8q22	27	9	segments	segment	NNS
cord-315781-dejh8q22	27	10	,	,	,
cord-315781-dejh8q22	27	11	showing	show	VBG
cord-315781-dejh8q22	27	12	that	that	IN
cord-315781-dejh8q22	27	13	the	the	DT
cord-315781-dejh8q22	27	14	groups	group	NNS
cord-315781-dejh8q22	27	15	were	be	VBD
cord-315781-dejh8q22	27	16	separated	separate	VBN
cord-315781-dejh8q22	27	17	by	by	IN
cord-315781-dejh8q22	27	18	similar	similar	JJ
cord-315781-dejh8q22	27	19	distances	distance	NNS
cord-315781-dejh8q22	27	20	.	.	.
cord-315781-dejh8q22	28	1	This	this	DT
cord-315781-dejh8q22	28	2	suggests	suggest	VBZ
cord-315781-dejh8q22	28	3	a	a	DT
cord-315781-dejh8q22	28	4	constant	constant	JJ
cord-315781-dejh8q22	28	5	mutation	mutation	NN
cord-315781-dejh8q22	28	6	rate	rate	NN
cord-315781-dejh8q22	28	7	among	among	IN
cord-315781-dejh8q22	28	8	the	the	DT
cord-315781-dejh8q22	28	9	segments	segment	NNS
cord-315781-dejh8q22	28	10	,	,	,
cord-315781-dejh8q22	28	11	which	which	WDT
cord-315781-dejh8q22	28	12	might	may	MD
cord-315781-dejh8q22	28	13	be	be	VB
cord-315781-dejh8q22	28	14	branched	branch	VBN
cord-315781-dejh8q22	28	15	from	from	IN
cord-315781-dejh8q22	28	16	the	the	DT
cord-315781-dejh8q22	28	17	ancestral	ancestral	JJ
cord-315781-dejh8q22	28	18	strain	strain	NN
cord-315781-dejh8q22	28	19	coincidentally	coincidentally	RB
cord-315781-dejh8q22	28	20	as	as	IN
cord-315781-dejh8q22	28	21	a	a	DT
cord-315781-dejh8q22	28	22	new	new	JJ
cord-315781-dejh8q22	28	23	set	set	NN
cord-315781-dejh8q22	28	24	of	of	IN
cord-315781-dejh8q22	28	25	viruses	virus	NNS
cord-315781-dejh8q22	28	26	.	.	.
cord-315781-dejh8q22	29	1	The	the	DT
cord-315781-dejh8q22	29	2	complete	complete	JJ
cord-315781-dejh8q22	29	3	separations	separation	NNS
cord-315781-dejh8q22	29	4	observed	observe	VBD
cord-315781-dejh8q22	29	5	negate	negate	VBP
cord-315781-dejh8q22	29	6	the	the	DT
cord-315781-dejh8q22	29	7	possibility	possibility	NN
cord-315781-dejh8q22	29	8	of	of	IN
cord-315781-dejh8q22	29	9	homologous	homologous	JJ
cord-315781-dejh8q22	29	10	recombination	recombination	NN
cord-315781-dejh8q22	29	11	between	between	IN
cord-315781-dejh8q22	29	12	viruses	virus	NNS
cord-315781-dejh8q22	29	13	,	,	,
cord-315781-dejh8q22	29	14	which	which	WDT
cord-315781-dejh8q22	29	15	would	would	MD
cord-315781-dejh8q22	29	16	yield	yield	VB
cord-315781-dejh8q22	29	17	some	some	DT
cord-315781-dejh8q22	29	18	intermediates	intermediate	NNS
cord-315781-dejh8q22	29	19	among	among	IN
cord-315781-dejh8q22	29	20	the	the	DT
cord-315781-dejh8q22	29	21	groups	group	NNS
cord-315781-dejh8q22	29	22	.	.	.
cord-315781-dejh8q22	30	1	Those	those	DT
cord-315781-dejh8q22	30	2	of	of	IN
cord-315781-dejh8q22	30	3	the	the	DT
cord-315781-dejh8q22	30	4	1930	1930	CD
cord-315781-dejh8q22	30	5	swine	swine	NN
cord-315781-dejh8q22	30	6	strain	strain	NN
cord-315781-dejh8q22	30	7	may	may	MD
cord-315781-dejh8q22	30	8	be	be	VB
cord-315781-dejh8q22	30	9	an	an	DT
cord-315781-dejh8q22	30	10	exception	exception	NN
cord-315781-dejh8q22	30	11	among	among	IN
cord-315781-dejh8q22	30	12	the	the	DT
cord-315781-dejh8q22	30	13	intermediates	intermediate	NNS
cord-315781-dejh8q22	30	14	,	,	,
cord-315781-dejh8q22	30	15	which	which	WDT
cord-315781-dejh8q22	30	16	will	will	MD
cord-315781-dejh8q22	30	17	be	be	VB
cord-315781-dejh8q22	30	18	discussed	discuss	VBN
cord-315781-dejh8q22	30	19	below	below	RB
cord-315781-dejh8q22	30	20	.	.	.
cord-315781-dejh8q22	31	1	The	the	DT
cord-315781-dejh8q22	31	2	combinations	combination	NNS
cord-315781-dejh8q22	31	3	of	of	IN
cord-315781-dejh8q22	31	4	segments	segment	NNS
cord-315781-dejh8q22	31	5	varied	vary	VBN
cord-315781-dejh8q22	31	6	in	in	IN
cord-315781-dejh8q22	31	7	swine	swine	NN
cord-315781-dejh8q22	31	8	strains	strain	NNS
cord-315781-dejh8q22	31	9	(	(	-LRB-
cord-315781-dejh8q22	31	10	Table	table	NN
cord-315781-dejh8q22	31	11	1	1	CD
cord-315781-dejh8q22	31	12	:	:	:
cord-315781-dejh8q22	31	13	PB	PB	NNP
cord-315781-dejh8q22	31	14	,	,	,
cord-315781-dejh8q22	31	15	RNA	RNA	NNP
cord-315781-dejh8q22	32	1	polymerase	polymerase	VB
cord-315781-dejh8q22	32	2	basic	basic	JJ
cord-315781-dejh8q22	32	3	protein	protein	NN
cord-315781-dejh8q22	32	4	;	;	:
cord-315781-dejh8q22	32	5	PA	PA	NNP
cord-315781-dejh8q22	32	6	,	,	,
cord-315781-dejh8q22	33	1	RNA	RNA	NNP
cord-315781-dejh8q22	33	2	polymerase	polymerase	NN
cord-315781-dejh8q22	33	3	acidic	acidic	JJ
cord-315781-dejh8q22	33	4	protein	protein	NN
cord-315781-dejh8q22	33	5	;	;	:
cord-315781-dejh8q22	33	6	NP	NP	NNP
cord-315781-dejh8q22	33	7	,	,	,
cord-315781-dejh8q22	33	8	nucleoprotein	nucleoprotein	NNP
cord-315781-dejh8q22	33	9	;	;	:
cord-315781-dejh8q22	33	10	NEP	NEP	NNP
cord-315781-dejh8q22	33	11	,	,	,
cord-315781-dejh8q22	33	12	nuclear	nuclear	JJ
cord-315781-dejh8q22	33	13	export	export	NN
cord-315781-dejh8q22	33	14	protein	protein	NN
cord-315781-dejh8q22	33	15	and	and	CC
cord-315781-dejh8q22	33	16	non	non	JJ
cord-315781-dejh8q22	33	17	-	-	JJ
cord-315781-dejh8q22	33	18	structural	structural	JJ
cord-315781-dejh8q22	33	19	protein	protein	NN
cord-315781-dejh8q22	33	20	)	)	-RRB-
cord-315781-dejh8q22	33	21	.	.	.
cord-315781-dejh8q22	34	1	In	in	IN
cord-315781-dejh8q22	34	2	contrast	contrast	NN
cord-315781-dejh8q22	34	3	,	,	,
cord-315781-dejh8q22	34	4	in	in	IN
cord-315781-dejh8q22	34	5	human	human	JJ
cord-315781-dejh8q22	34	6	strains	strain	NNS
cord-315781-dejh8q22	34	7	,	,	,
cord-315781-dejh8q22	34	8	the	the	DT
cord-315781-dejh8q22	34	9	combinations	combination	NNS
cord-315781-dejh8q22	34	10	were	be	VBD
cord-315781-dejh8q22	34	11	all	all	DT
cord-315781-dejh8q22	34	12	M	M	NNP
cord-315781-dejh8q22	34	13	or	or	CC
cord-315781-dejh8q22	34	14	all	all	DT
cord-315781-dejh8q22	35	1	R.	R.	NNP
cord-315781-dejh8q22	36	1	It	-PRON-	PRP
cord-315781-dejh8q22	36	2	should	should	MD
cord-315781-dejh8q22	36	3	be	be	VB
cord-315781-dejh8q22	36	4	noted	note	VBN
cord-315781-dejh8q22	36	5	that	that	IN
cord-315781-dejh8q22	36	6	avian	avian	JJ
cord-315781-dejh8q22	36	7	viruses	virus	NNS
cord-315781-dejh8q22	36	8	showed	show	VBD
cord-315781-dejh8q22	36	9	lower	low	JJR
cord-315781-dejh8q22	36	10	PC	pc	NN
cord-315781-dejh8q22	36	11	values	value	NNS
cord-315781-dejh8q22	36	12	and	and	CC
cord-315781-dejh8q22	36	13	appeared	appear	VBD
cord-315781-dejh8q22	36	14	around	around	IN
cord-315781-dejh8q22	36	15	the	the	DT
cord-315781-dejh8q22	36	16	centre	centre	NN
cord-315781-dejh8q22	36	17	of	of	IN
cord-315781-dejh8q22	36	18	the	the	DT
cord-315781-dejh8q22	36	19	PCA	PCA	NNP
cord-315781-dejh8q22	36	20	,	,	,
cord-315781-dejh8q22	36	21	while	while	IN
cord-315781-dejh8q22	36	22	swine	swine	NN
cord-315781-dejh8q22	36	23	and	and	CC
cord-315781-dejh8q22	36	24	human	human	NN
cord-315781-dejh8q22	36	25	viruses	virus	NNS
cord-315781-dejh8q22	36	26	exhibited	exhibit	VBD
cord-315781-dejh8q22	36	27	extreme	extreme	JJ
cord-315781-dejh8q22	36	28	values	value	NNS
cord-315781-dejh8q22	36	29	(	(	-LRB-
cord-315781-dejh8q22	36	30	Figs	fig	NNS
cord-315781-dejh8q22	36	31	.	.	.
cord-315781-dejh8q22	37	1	1C	1C	NNP
cord-315781-dejh8q22	37	2	and	and	CC
cord-315781-dejh8q22	37	3	S2	S2	NNP
cord-315781-dejh8q22	37	4	)	)	-RRB-
cord-315781-dejh8q22	37	5	.	.	.
cord-315781-dejh8q22	38	1	Thus	thus	RB
cord-315781-dejh8q22	38	2	,	,	,
cord-315781-dejh8q22	38	3	avian	avian	JJ
cord-315781-dejh8q22	38	4	viruses	virus	NNS
cord-315781-dejh8q22	38	5	had	have	VBD
cord-315781-dejh8q22	38	6	sequences	sequence	NNS
cord-315781-dejh8q22	38	7	that	that	WDT
cord-315781-dejh8q22	38	8	were	be	VBD
cord-315781-dejh8q22	38	9	similar	similar	JJ
cord-315781-dejh8q22	38	10	to	to	IN
cord-315781-dejh8q22	38	11	the	the	DT
cord-315781-dejh8q22	38	12	average	average	NN
cord-315781-dejh8q22	38	13	among	among	IN
cord-315781-dejh8q22	38	14	samples	sample	NNS
cord-315781-dejh8q22	38	15	at	at	IN
cord-315781-dejh8q22	38	16	amino	amino	NN
cord-315781-dejh8q22	38	17	acids	acid	NNS
cord-315781-dejh8q22	38	18	that	that	WDT
cord-315781-dejh8q22	38	19	were	be	VBD
cord-315781-dejh8q22	38	20	characteristic	characteristic	JJ
cord-315781-dejh8q22	38	21	to	to	IN
cord-315781-dejh8q22	38	22	the	the	DT
cord-315781-dejh8q22	38	23	three	three	CD
cord-315781-dejh8q22	38	24	groups	group	NNS
cord-315781-dejh8q22	38	25	of	of	IN
cord-315781-dejh8q22	38	26	human	human	NN
cord-315781-dejh8q22	38	27	and	and	CC
cord-315781-dejh8q22	38	28	swine	swine	NN
cord-315781-dejh8q22	38	29	viruses	virus	NNS
cord-315781-dejh8q22	38	30	:	:	:
cord-315781-dejh8q22	38	31	R	r	NN
cord-315781-dejh8q22	38	32	,	,	,
cord-315781-dejh8q22	38	33	M	M	NNP
cord-315781-dejh8q22	38	34	,	,	,
cord-315781-dejh8q22	38	35	and	and	CC
cord-315781-dejh8q22	38	36	U.	U.	NNP
cord-315781-dejh8q22	38	37	Avian	avian	JJ
cord-315781-dejh8q22	38	38	samples	sample	NNS
cord-315781-dejh8q22	38	39	also	also	RB
cord-315781-dejh8q22	38	40	showed	show	VBD
cord-315781-dejh8q22	38	41	characteristic	characteristic	JJ
cord-315781-dejh8q22	38	42	motifs	motif	NNS
cord-315781-dejh8q22	38	43	at	at	IN
cord-315781-dejh8q22	38	44	other	other	JJ
cord-315781-dejh8q22	38	45	positions	position	NNS
cord-315781-dejh8q22	38	46	,	,	,
cord-315781-dejh8q22	38	47	which	which	WDT
cord-315781-dejh8q22	38	48	may	may	MD
cord-315781-dejh8q22	38	49	appear	appear	VB
cord-315781-dejh8q22	38	50	in	in	IN
cord-315781-dejh8q22	38	51	lower	low	JJR
cord-315781-dejh8q22	38	52	PCs	pc	NNS
cord-315781-dejh8q22	38	53	.	.	.
cord-315781-dejh8q22	39	1	The	the	DT
cord-315781-dejh8q22	39	2	relationships	relationship	NNS
cord-315781-dejh8q22	39	3	observed	observe	VBD
cord-315781-dejh8q22	39	4	among	among	IN
cord-315781-dejh8q22	39	5	the	the	DT
cord-315781-dejh8q22	39	6	strains	strain	NNS
cord-315781-dejh8q22	39	7	presented	present	VBN
cord-315781-dejh8q22	39	8	here	here	RB
cord-315781-dejh8q22	39	9	are	be	VBP
cord-315781-dejh8q22	39	10	different	different	JJ
cord-315781-dejh8q22	39	11	from	from	IN
cord-315781-dejh8q22	39	12	the	the	DT
cord-315781-dejh8q22	39	13	classic	classic	JJ
cord-315781-dejh8q22	39	14	ones	one	NNS
cord-315781-dejh8q22	39	15	4	4	CD
cord-315781-dejh8q22	39	16	,	,	,
cord-315781-dejh8q22	39	17	[	[	-LRB-
cord-315781-dejh8q22	39	18	8	8	CD
cord-315781-dejh8q22	39	19	]	]	-RRB-
cord-315781-dejh8q22	39	20	[	[	-LRB-
cord-315781-dejh8q22	39	21	9	9	CD
cord-315781-dejh8q22	39	22	]	]	-RRB-
cord-315781-dejh8q22	39	23	[	[	-LRB-
cord-315781-dejh8q22	39	24	10	10	CD
cord-315781-dejh8q22	39	25	]	]	-RRB-
cord-315781-dejh8q22	39	26	[	[	-LRB-
cord-315781-dejh8q22	39	27	11	11	CD
cord-315781-dejh8q22	39	28	]	]	-RRB-
cord-315781-dejh8q22	39	29	[	[	-LRB-
cord-315781-dejh8q22	39	30	12	12	CD
cord-315781-dejh8q22	39	31	]	]	-RRB-
cord-315781-dejh8q22	39	32	in	in	IN
cord-315781-dejh8q22	39	33	several	several	JJ
cord-315781-dejh8q22	39	34	elements	element	NNS
cord-315781-dejh8q22	39	35	.	.	.
cord-315781-dejh8q22	40	1	For	for	IN
cord-315781-dejh8q22	40	2	example	example	NN
cord-315781-dejh8q22	40	3	,	,	,
cord-315781-dejh8q22	40	4	the	the	DT
cord-315781-dejh8q22	40	5	number	number	NN
cord-315781-dejh8q22	40	6	of	of	IN
cord-315781-dejh8q22	40	7	swine	swine	NN
cord-315781-dejh8q22	40	8	classes	class	NNS
cord-315781-dejh8q22	40	9	was	be	VBD
cord-315781-dejh8q22	40	10	conspicuous	conspicuous	JJ
cord-315781-dejh8q22	40	11	.	.	.
cord-315781-dejh8q22	41	1	Previously	previously	RB
cord-315781-dejh8q22	41	2	,	,	,
cord-315781-dejh8q22	41	3	"	"	``
cord-315781-dejh8q22	41	4	triple	triple	JJ
cord-315781-dejh8q22	41	5	reassortant	reassortant	NN
cord-315781-dejh8q22	41	6	"	"	''
cord-315781-dejh8q22	41	7	,	,	,
cord-315781-dejh8q22	41	8	"	"	``
cord-315781-dejh8q22	41	9	Eurasian	eurasian	JJ
cord-315781-dejh8q22	41	10	avian	avian	NN
cord-315781-dejh8q22	41	11	-	-	HYPH
cord-315781-dejh8q22	41	12	like	like	JJ
cord-315781-dejh8q22	41	13	,	,	,
cord-315781-dejh8q22	41	14	"	"	''
cord-315781-dejh8q22	41	15	and	and	CC
cord-315781-dejh8q22	41	16	"	"	``
cord-315781-dejh8q22	41	17	classic	classic	JJ
cord-315781-dejh8q22	41	18	"	"	''
cord-315781-dejh8q22	41	19	viruses	virus	NNS
cord-315781-dejh8q22	41	20	were	be	VBD
cord-315781-dejh8q22	41	21	estimated	estimate	VBN
cord-315781-dejh8q22	41	22	8	8	CD
cord-315781-dejh8q22	41	23	.	.	.
cord-315781-dejh8q22	42	1	However	however	RB
cord-315781-dejh8q22	42	2	,	,	,
cord-315781-dejh8q22	42	3	the	the	DT
cord-315781-dejh8q22	42	4	triple	triple	JJ
cord-315781-dejh8q22	42	5	-	-	HYPH
cord-315781-dejh8q22	42	6	reassortant	reassortant	JJ
cord-315781-dejh8q22	42	7	group	group	NN
cord-315781-dejh8q22	42	8	was	be	VBD
cord-315781-dejh8q22	42	9	absorbed	absorb	VBN
cord-315781-dejh8q22	42	10	into	into	IN
cord-315781-dejh8q22	42	11	the	the	DT
cord-315781-dejh8q22	42	12	two	two	CD
cord-315781-dejh8q22	42	13	groups	group	NNS
cord-315781-dejh8q22	42	14	,	,	,
cord-315781-dejh8q22	42	15	U	U	NNP
cord-315781-dejh8q22	42	16	and	and	CC
cord-315781-dejh8q22	42	17	M	M	NNP
cord-315781-dejh8q22	42	18	,	,	,
cord-315781-dejh8q22	42	19	and	and	CC
cord-315781-dejh8q22	42	20	the	the	DT
cord-315781-dejh8q22	42	21	sorting	sorting	NN
cord-315781-dejh8q22	42	22	differed	differ	VBD
cord-315781-dejh8q22	42	23	among	among	IN
cord-315781-dejh8q22	42	24	segments	segment	NNS
cord-315781-dejh8q22	42	25	in	in	IN
cord-315781-dejh8q22	42	26	the	the	DT
cord-315781-dejh8q22	42	27	strains	strain	NNS
cord-315781-dejh8q22	42	28	presented	present	VBN
cord-315781-dejh8q22	42	29	here	here	RB
cord-315781-dejh8q22	42	30	(	(	-LRB-
cord-315781-dejh8q22	42	31	Fig	Fig	NNP
cord-315781-dejh8q22	42	32	.	.	.
cord-315781-dejh8q22	42	33	S2	s2	NN
cord-315781-dejh8q22	42	34	,	,	,
cord-315781-dejh8q22	42	35	blue	blue	JJ
cord-315781-dejh8q22	42	36	,	,	,
cord-315781-dejh8q22	42	37	Table	table	NN
cord-315781-dejh8q22	42	38	1	1	CD
cord-315781-dejh8q22	42	39	)	)	-RRB-
cord-315781-dejh8q22	42	40	.	.	.
cord-315781-dejh8q22	43	1	The	the	DT
cord-315781-dejh8q22	43	2	frequency	frequency	NN
cord-315781-dejh8q22	43	3	of	of	IN
cord-315781-dejh8q22	43	4	shifts	shift	NNS
cord-315781-dejh8q22	43	5	detected	detect	VBN
cord-315781-dejh8q22	43	6	was	be	VBD
cord-315781-dejh8q22	43	7	another	another	DT
cord-315781-dejh8q22	43	8	of	of	IN
cord-315781-dejh8q22	43	9	the	the	DT
cord-315781-dejh8q22	43	10	differences	difference	NNS
cord-315781-dejh8q22	43	11	detected	detect	VBN
cord-315781-dejh8q22	43	12	;	;	,
cord-315781-dejh8q22	43	13	i.e.	i.e.	FW
cord-315781-dejh8q22	43	14	,	,	,
cord-315781-dejh8q22	43	15	only	only	RB
cord-315781-dejh8q22	43	16	a	a	DT
cord-315781-dejh8q22	43	17	few	few	JJ
cord-315781-dejh8q22	43	18	shifts	shift	NNS
cord-315781-dejh8q22	43	19	were	be	VBD
cord-315781-dejh8q22	43	20	estimated	estimate	VBN
cord-315781-dejh8q22	43	21	4	4	CD
cord-315781-dejh8q22	43	22	,	,	,
cord-315781-dejh8q22	43	23	8	8	CD
cord-315781-dejh8q22	43	24	,	,	,
cord-315781-dejh8q22	43	25	9	9	CD
cord-315781-dejh8q22	43	26	,	,	,
cord-315781-dejh8q22	43	27	13	13	CD
cord-315781-dejh8q22	43	28	.	.	.
cord-315781-dejh8q22	44	1	These	these	DT
cord-315781-dejh8q22	44	2	may	may	MD
cord-315781-dejh8q22	44	3	be	be	VB
cord-315781-dejh8q22	44	4	derived	derive	VBN
cord-315781-dejh8q22	44	5	from	from	IN
cord-315781-dejh8q22	44	6	differences	difference	NNS
cord-315781-dejh8q22	44	7	in	in	IN
cord-315781-dejh8q22	44	8	the	the	DT
cord-315781-dejh8q22	44	9	classification	classification	NN
cord-315781-dejh8q22	44	10	methods	method	NNS
cord-315781-dejh8q22	44	11	used	use	VBN
cord-315781-dejh8q22	44	12	,	,	,
cord-315781-dejh8q22	44	13	which	which	WDT
cord-315781-dejh8q22	44	14	will	will	MD
cord-315781-dejh8q22	44	15	be	be	VB
cord-315781-dejh8q22	44	16	discussed	discuss	VBN
cord-315781-dejh8q22	44	17	below	below	RB
cord-315781-dejh8q22	44	18	.	.	.
cord-315781-dejh8q22	45	1	Only	only	RB
cord-315781-dejh8q22	45	2	limited	limited	JJ
cord-315781-dejh8q22	45	3	positions	position	NNS
cord-315781-dejh8q22	45	4	of	of	IN
cord-315781-dejh8q22	45	5	a	a	DT
cord-315781-dejh8q22	45	6	virus	virus	NN
cord-315781-dejh8q22	45	7	can	can	MD
cord-315781-dejh8q22	45	8	be	be	VB
cord-315781-dejh8q22	45	9	changed	change	VBN
cord-315781-dejh8q22	45	10	.	.	.
cord-315781-dejh8q22	46	1	Although	although	IN
cord-315781-dejh8q22	46	2	amino	amino	NN
cord-315781-dejh8q22	46	3	acid	acid	NN
cord-315781-dejh8q22	46	4	sequences	sequence	NNS
cord-315781-dejh8q22	46	5	varied	varied	JJ
cord-315781-dejh8q22	46	6	among	among	IN
cord-315781-dejh8q22	46	7	the	the	DT
cord-315781-dejh8q22	46	8	types	type	NNS
cord-315781-dejh8q22	46	9	,	,	,
cord-315781-dejh8q22	46	10	the	the	DT
cord-315781-dejh8q22	46	11	three	three	CD
cord-315781-dejh8q22	46	12	-	-	HYPH
cord-315781-dejh8q22	46	13	dimensional	dimensional	JJ
cord-315781-dejh8q22	46	14	(	(	-LRB-
cord-315781-dejh8q22	46	15	3D	3D	NNP
cord-315781-dejh8q22	46	16	)	)	-RRB-
cord-315781-dejh8q22	46	17	structures	structure	NNS
cord-315781-dejh8q22	46	18	of	of	IN
cord-315781-dejh8q22	46	19	the	the	DT
cord-315781-dejh8q22	46	20	viruses	virus	NNS
cord-315781-dejh8q22	46	21	were	be	VBD
cord-315781-dejh8q22	46	22	rather	rather	RB
cord-315781-dejh8q22	46	23	conserved	conserve	VBN
cord-315781-dejh8q22	46	24	regarding	regard	VBG
cord-315781-dejh8q22	46	25	HA	HA	NNP
cord-315781-dejh8q22	46	26	(	(	-LRB-
cord-315781-dejh8q22	46	27	Fig	fig	NN
cord-315781-dejh8q22	46	28	.	.	.
cord-315781-dejh8q22	46	29	S3A	s3a	CD
cord-315781-dejh8q22	46	30	)	)	-RRB-
cord-315781-dejh8q22	46	31	,	,	,
cord-315781-dejh8q22	46	32	which	which	WDT
cord-315781-dejh8q22	46	33	suggests	suggest	VBZ
cord-315781-dejh8q22	46	34	that	that	IN
cord-315781-dejh8q22	46	35	at	at	IN
cord-315781-dejh8q22	46	36	least	least	JJS
cord-315781-dejh8q22	46	37	some	some	DT
cord-315781-dejh8q22	46	38	positions	position	NNS
cord-315781-dejh8q22	46	39	were	be	VBD
cord-315781-dejh8q22	46	40	conserved	conserve	VBN
cord-315781-dejh8q22	46	41	.	.	.
cord-315781-dejh8q22	47	1	In	in	IN
cord-315781-dejh8q22	47	2	fact	fact	NN
cord-315781-dejh8q22	47	3	,	,	,
cord-315781-dejh8q22	47	4	several	several	JJ
cord-315781-dejh8q22	47	5	positions	position	NNS
cord-315781-dejh8q22	47	6	were	be	VBD
cord-315781-dejh8q22	47	7	common	common	JJ
cord-315781-dejh8q22	47	8	to	to	TO
cord-315781-dejh8q22	47	9	type	type	VB
cord-315781-dejh8q22	47	10	A	a	DT
cord-315781-dejh8q22	47	11	viruses	virus	NNS
cord-315781-dejh8q22	47	12	;	;	:
cord-315781-dejh8q22	47	13	e.g.	e.g.	RB
cord-315781-dejh8q22	47	14	,	,	,
cord-315781-dejh8q22	47	15	they	-PRON-	PRP
cord-315781-dejh8q22	47	16	were	be	VBD
cord-315781-dejh8q22	47	17	located	locate	VBN
cord-315781-dejh8q22	47	18	at	at	IN
cord-315781-dejh8q22	47	19	the	the	DT
cord-315781-dejh8q22	47	20	core	core	NN
cord-315781-dejh8q22	47	21	of	of	IN
cord-315781-dejh8q22	47	22	the	the	DT
cord-315781-dejh8q22	47	23	protein	protein	NN
cord-315781-dejh8q22	47	24	,	,	,
cord-315781-dejh8q22	47	25	the	the	DT
cord-315781-dejh8q22	47	26	rod	rod	NN
cord-315781-dejh8q22	47	27	of	of	IN
cord-315781-dejh8q22	47	28	the	the	DT
cord-315781-dejh8q22	47	29	alpha	alpha	NN
cord-315781-dejh8q22	47	30	helix	helix	NN
cord-315781-dejh8q22	47	31	(	(	-LRB-
cord-315781-dejh8q22	47	32	Fig	Fig	NNP
cord-315781-dejh8q22	47	33	.	.	.
cord-315781-dejh8q22	47	34	S3B	s3b	LS
cord-315781-dejh8q22	47	35	)	)	-RRB-
cord-315781-dejh8q22	47	36	.	.	.
cord-315781-dejh8q22	48	1	These	these	DT
cord-315781-dejh8q22	48	2	positions	position	NNS
cord-315781-dejh8q22	48	3	seem	seem	VBP
cord-315781-dejh8q22	48	4	to	to	TO
cord-315781-dejh8q22	48	5	be	be	VB
cord-315781-dejh8q22	48	6	important	important	JJ
cord-315781-dejh8q22	48	7	for	for	IN
cord-315781-dejh8q22	48	8	the	the	DT
cord-315781-dejh8q22	48	9	maintenance	maintenance	NN
cord-315781-dejh8q22	48	10	of	of	IN
cord-315781-dejh8q22	48	11	the	the	DT
cord-315781-dejh8q22	48	12	protein	protein	NN
cord-315781-dejh8q22	48	13	functions	function	NNS
cord-315781-dejh8q22	48	14	.	.	.
cord-315781-dejh8q22	49	1	From	from	IN
cord-315781-dejh8q22	49	2	1977	1977	CD
cord-315781-dejh8q22	49	3	to	to	IN
cord-315781-dejh8q22	49	4	2009	2009	CD
cord-315781-dejh8q22	49	5	,	,	,
cord-315781-dejh8q22	49	6	many	many	JJ
cord-315781-dejh8q22	49	7	residues	residue	NNS
cord-315781-dejh8q22	49	8	in	in	IN
cord-315781-dejh8q22	49	9	the	the	DT
cord-315781-dejh8q22	49	10	type	type	NN
cord-315781-dejh8q22	49	11	R	r	NN
cord-315781-dejh8q22	49	12	viruses	virus	NNS
cord-315781-dejh8q22	49	13	changed	change	VBD
cord-315781-dejh8q22	49	14	(	(	-LRB-
cord-315781-dejh8q22	49	15	Fig	Fig	NNP
cord-315781-dejh8q22	49	16	.	.	.
cord-315781-dejh8q22	49	17	S3C	S3C	NNS
cord-315781-dejh8q22	49	18	,	,	,
cord-315781-dejh8q22	49	19	asterisks	asterisk	NNS
cord-315781-dejh8q22	49	20	)	)	-RRB-
cord-315781-dejh8q22	49	21	.	.	.
cord-315781-dejh8q22	50	1	They	-PRON-	PRP
cord-315781-dejh8q22	50	2	are	be	VBP
cord-315781-dejh8q22	50	3	mainly	mainly	RB
cord-315781-dejh8q22	50	4	located	locate	VBN
cord-315781-dejh8q22	50	5	on	on	IN
cord-315781-dejh8q22	50	6	the	the	DT
cord-315781-dejh8q22	50	7	surface	surface	NN
cord-315781-dejh8q22	50	8	of	of	IN
cord-315781-dejh8q22	50	9	the	the	DT
cord-315781-dejh8q22	50	10	protein	protein	NN
cord-315781-dejh8q22	50	11	,	,	,
cord-315781-dejh8q22	50	12	where	where	WRB
cord-315781-dejh8q22	50	13	they	-PRON-	PRP
cord-315781-dejh8q22	50	14	may	may	MD
cord-315781-dejh8q22	50	15	form	form	VB
cord-315781-dejh8q22	50	16	epitopes	epitope	NNS
cord-315781-dejh8q22	50	17	.	.	.
cord-315781-dejh8q22	51	1	Therefore	therefore	RB
cord-315781-dejh8q22	51	2	,	,	,
cord-315781-dejh8q22	51	3	the	the	DT
cord-315781-dejh8q22	51	4	changes	change	NNS
cord-315781-dejh8q22	51	5	that	that	WDT
cord-315781-dejh8q22	51	6	occurred	occur	VBD
cord-315781-dejh8q22	51	7	at	at	IN
cord-315781-dejh8q22	51	8	those	those	DT
cord-315781-dejh8q22	51	9	positions	position	NNS
cord-315781-dejh8q22	51	10	would	would	MD
cord-315781-dejh8q22	51	11	be	be	VB
cord-315781-dejh8q22	51	12	beneficial	beneficial	JJ
cord-315781-dejh8q22	51	13	for	for	IN
cord-315781-dejh8q22	51	14	escaping	escape	VBG
cord-315781-dejh8q22	51	15	the	the	DT
cord-315781-dejh8q22	51	16	immune	immune	JJ
cord-315781-dejh8q22	51	17	system	system	NN
cord-315781-dejh8q22	51	18	of	of	IN
cord-315781-dejh8q22	51	19	humans	human	NNS
cord-315781-dejh8q22	51	20	.	.	.
cord-315781-dejh8q22	52	1	Conversely	conversely	RB
cord-315781-dejh8q22	52	2	,	,	,
cord-315781-dejh8q22	52	3	we	-PRON-	PRP
cord-315781-dejh8q22	52	4	identified	identify	VBD
cord-315781-dejh8q22	52	5	characteristic	characteristic	JJ
cord-315781-dejh8q22	52	6	residues	residue	NNS
cord-315781-dejh8q22	52	7	of	of	IN
cord-315781-dejh8q22	52	8	the	the	DT
cord-315781-dejh8q22	52	9	R	r	NN
cord-315781-dejh8q22	52	10	,	,	,
cord-315781-dejh8q22	52	11	M	M	NNP
cord-315781-dejh8q22	52	12	,	,	,
cord-315781-dejh8q22	52	13	and	and	CC
cord-315781-dejh8q22	52	14	U	U	NNP
cord-315781-dejh8q22	52	15	groups	group	NNS
cord-315781-dejh8q22	52	16	,	,	,
cord-315781-dejh8q22	52	17	which	which	WDT
cord-315781-dejh8q22	52	18	were	be	VBD
cord-315781-dejh8q22	52	19	indicated	indicate	VBN
cord-315781-dejh8q22	52	20	by	by	IN
cord-315781-dejh8q22	52	21	the	the	DT
cord-315781-dejh8q22	52	22	hexagonal	hexagonal	JJ
cord-315781-dejh8q22	52	23	directions	direction	NNS
cord-315781-dejh8q22	52	24	of	of	IN
cord-315781-dejh8q22	52	25	PC1	PC1	NNP
cord-315781-dejh8q22	52	26	and	and	CC
cord-315781-dejh8q22	52	27	PC2	PC2	NNP
cord-315781-dejh8q22	52	28	(	(	-LRB-
cord-315781-dejh8q22	52	29	Fig	Fig	NNP
cord-315781-dejh8q22	52	30	.	.	.
cord-315781-dejh8q22	53	1	S1E	S1E	NNP
cord-315781-dejh8q22	53	2	,	,	,
cord-315781-dejh8q22	53	3	green	green	NNP
cord-315781-dejh8q22	53	4	)	)	-RRB-
cord-315781-dejh8q22	53	5	.	.	.
cord-315781-dejh8q22	54	1	They	-PRON-	PRP
cord-315781-dejh8q22	54	2	exhibited	exhibit	VBD
cord-315781-dejh8q22	54	3	higher	high	JJR
cord-315781-dejh8q22	54	4	scores	score	NNS
cord-315781-dejh8q22	54	5	because	because	IN
cord-315781-dejh8q22	54	6	they	-PRON-	PRP
cord-315781-dejh8q22	54	7	appeared	appear	VBD
cord-315781-dejh8q22	54	8	unchanged	unchanged	JJ
cord-315781-dejh8q22	54	9	in	in	IN
cord-315781-dejh8q22	54	10	only	only	RB
cord-315781-dejh8q22	54	11	one	one	CD
cord-315781-dejh8q22	54	12	of	of	IN
cord-315781-dejh8q22	54	13	the	the	DT
cord-315781-dejh8q22	54	14	groups	group	NNS
cord-315781-dejh8q22	55	1	(	(	-LRB-
cord-315781-dejh8q22	55	2	Fig	Fig	NNP
cord-315781-dejh8q22	55	3	.	.	.
cord-315781-dejh8q22	55	4	S3C	S3C	NNS
cord-315781-dejh8q22	55	5	)	)	-RRB-
cord-315781-dejh8q22	55	6	.	.	.
cord-315781-dejh8q22	56	1	These	these	DT
cord-315781-dejh8q22	56	2	residues	residue	NNS
cord-315781-dejh8q22	56	3	might	may	MD
cord-315781-dejh8q22	56	4	play	play	VB
cord-315781-dejh8q22	56	5	important	important	JJ
cord-315781-dejh8q22	56	6	roles	role	NNS
cord-315781-dejh8q22	56	7	in	in	IN
cord-315781-dejh8q22	56	8	the	the	DT
cord-315781-dejh8q22	56	9	function	function	NN
cord-315781-dejh8q22	56	10	of	of	IN
cord-315781-dejh8q22	56	11	the	the	DT
cord-315781-dejh8q22	56	12	respective	respective	JJ
cord-315781-dejh8q22	56	13	protein	protein	NN
cord-315781-dejh8q22	56	14	.	.	.
cord-315781-dejh8q22	57	1	Let	let	VB
cord-315781-dejh8q22	57	2	us	-PRON-	PRP
cord-315781-dejh8q22	57	3	consider	consider	VB
cord-315781-dejh8q22	57	4	the	the	DT
cord-315781-dejh8q22	57	5	annual	annual	JJ
cord-315781-dejh8q22	57	6	changes	change	NNS
cord-315781-dejh8q22	57	7	of	of	IN
cord-315781-dejh8q22	57	8	the	the	DT
cord-315781-dejh8q22	57	9	group	group	NN
cord-315781-dejh8q22	57	10	R	r	NN
cord-315781-dejh8q22	57	11	in	in	IN
cord-315781-dejh8q22	57	12	humans	human	NNS
cord-315781-dejh8q22	57	13	(	(	-LRB-
cord-315781-dejh8q22	57	14	Figs	fig	NNS
cord-315781-dejh8q22	57	15	.	.	.
cord-315781-dejh8q22	58	1	2A	2a	LS
cord-315781-dejh8q22	58	2	-	-	HYPH
cord-315781-dejh8q22	58	3	C	C	NNP
cord-315781-dejh8q22	58	4	and	and	CC
cord-315781-dejh8q22	58	5	S4A	S4A	NNP
cord-315781-dejh8q22	58	6	)	)	-RRB-
cord-315781-dejh8q22	58	7	.	.	.
cord-315781-dejh8q22	59	1	In	in	IN
cord-315781-dejh8q22	59	2	any	any	DT
cord-315781-dejh8q22	59	3	given	give	VBN
cord-315781-dejh8q22	59	4	year	year	NN
cord-315781-dejh8q22	59	5	,	,	,
cord-315781-dejh8q22	59	6	only	only	RB
cord-315781-dejh8q22	59	7	a	a	DT
cord-315781-dejh8q22	59	8	few	few	JJ
cord-315781-dejh8q22	59	9	variations	variation	NNS
cord-315781-dejh8q22	59	10	of	of	IN
cord-315781-dejh8q22	59	11	the	the	DT
cord-315781-dejh8q22	59	12	H1	H1	NNP
cord-315781-dejh8q22	59	13	subtypes	subtype	NNS
cord-315781-dejh8q22	59	14	were	be	VBD
cord-315781-dejh8q22	59	15	found	find	VBN
cord-315781-dejh8q22	59	16	.	.	.
cord-315781-dejh8q22	60	1	They	-PRON-	PRP
cord-315781-dejh8q22	60	2	were	be	VBD
cord-315781-dejh8q22	60	3	changed	change	VBN
cord-315781-dejh8q22	60	4	slightly	slightly	RB
cord-315781-dejh8q22	60	5	by	by	IN
cord-315781-dejh8q22	60	6	drifting	drift	VBG
cord-315781-dejh8q22	60	7	and	and	CC
cord-315781-dejh8q22	60	8	were	be	VBD
cord-315781-dejh8q22	60	9	detected	detect	VBN
cord-315781-dejh8q22	60	10	in	in	IN
cord-315781-dejh8q22	60	11	another	another	DT
cord-315781-dejh8q22	60	12	area	area	NN
cord-315781-dejh8q22	60	13	in	in	IN
cord-315781-dejh8q22	60	14	the	the	DT
cord-315781-dejh8q22	60	15	subsequent	subsequent	JJ
cord-315781-dejh8q22	60	16	year	year	NN
cord-315781-dejh8q22	60	17	(	(	-LRB-
cord-315781-dejh8q22	60	18	Figs	fig	NNS
cord-315781-dejh8q22	60	19	.	.	.
cord-315781-dejh8q22	61	1	2D	2D	NNP
cord-315781-dejh8q22	61	2	and	and	CC
cord-315781-dejh8q22	61	3	S5	S5	NNP
cord-315781-dejh8q22	61	4	)	)	-RRB-
cord-315781-dejh8q22	61	5	.	.	.
cord-315781-dejh8q22	62	1	As	as	IN
cord-315781-dejh8q22	62	2	the	the	DT
cord-315781-dejh8q22	62	3	lives	life	NNS
cord-315781-dejh8q22	62	4	of	of	IN
cord-315781-dejh8q22	62	5	humans	human	NNS
cord-315781-dejh8q22	62	6	span	span	VBP
cord-315781-dejh8q22	62	7	several	several	JJ
cord-315781-dejh8q22	62	8	decades	decade	NNS
cord-315781-dejh8q22	62	9	,	,	,
cord-315781-dejh8q22	62	10	they	-PRON-	PRP
cord-315781-dejh8q22	62	11	might	may	MD
cord-315781-dejh8q22	62	12	be	be	VB
cord-315781-dejh8q22	62	13	immune	immune	JJ
cord-315781-dejh8q22	62	14	to	to	IN
cord-315781-dejh8q22	62	15	viruses	virus	NNS
cord-315781-dejh8q22	62	16	that	that	WDT
cord-315781-dejh8q22	62	17	appeared	appear	VBD
cord-315781-dejh8q22	62	18	in	in	IN
cord-315781-dejh8q22	62	19	the	the	DT
cord-315781-dejh8q22	62	20	past	past	NN
cord-315781-dejh8q22	62	21	.	.	.
cord-315781-dejh8q22	63	1	This	this	DT
cord-315781-dejh8q22	63	2	may	may	MD
cord-315781-dejh8q22	63	3	represent	represent	VB
cord-315781-dejh8q22	63	4	a	a	DT
cord-315781-dejh8q22	63	5	selective	selective	JJ
cord-315781-dejh8q22	63	6	pressure	pressure	NN
cord-315781-dejh8q22	63	7	to	to	IN
cord-315781-dejh8q22	63	8	viruses	virus	NNS
cord-315781-dejh8q22	63	9	.	.	.
cord-315781-dejh8q22	64	1	Moreover	moreover	RB
cord-315781-dejh8q22	64	2	,	,	,
cord-315781-dejh8q22	64	3	humans	human	NNS
cord-315781-dejh8q22	64	4	may	may	MD
cord-315781-dejh8q22	64	5	travel	travel	VB
cord-315781-dejh8q22	64	6	to	to	IN
cord-315781-dejh8q22	64	7	other	other	JJ
cord-315781-dejh8q22	64	8	countries	country	NNS
cord-315781-dejh8q22	64	9	by	by	IN
cord-315781-dejh8q22	64	10	air	air	NN
cord-315781-dejh8q22	64	11	while	while	IN
cord-315781-dejh8q22	64	12	carrying	carry	VBG
cord-315781-dejh8q22	64	13	viruses	virus	NNS
cord-315781-dejh8q22	64	14	.	.	.
cord-315781-dejh8q22	65	1	Hence	hence	RB
cord-315781-dejh8q22	65	2	,	,	,
cord-315781-dejh8q22	65	3	the	the	DT
cord-315781-dejh8q22	65	4	viruses	virus	NNS
cord-315781-dejh8q22	65	5	spread	spread	VBP
cord-315781-dejh8q22	65	6	worldwide	worldwide	RB
cord-315781-dejh8q22	65	7	,	,	,
cord-315781-dejh8q22	65	8	unifying	unify	VBG
cord-315781-dejh8q22	65	9	the	the	DT
cord-315781-dejh8q22	65	10	outbreaking	outbreake	VBG
cord-315781-dejh8q22	65	11	strains	strain	NNS
cord-315781-dejh8q22	65	12	.	.	.
cord-315781-dejh8q22	66	1	Although	although	IN
cord-315781-dejh8q22	66	2	changes	change	NNS
cord-315781-dejh8q22	66	3	in	in	IN
cord-315781-dejh8q22	66	4	one	one	CD
cord-315781-dejh8q22	66	5	to	to	IN
cord-315781-dejh8q22	66	6	several	several	JJ
cord-315781-dejh8q22	66	7	residues	residue	NNS
cord-315781-dejh8q22	66	8	may	may	MD
cord-315781-dejh8q22	66	9	be	be	VB
cord-315781-dejh8q22	66	10	sufficient	sufficient	JJ
cord-315781-dejh8q22	66	11	to	to	TO
cord-315781-dejh8q22	66	12	escape	escape	VB
cord-315781-dejh8q22	66	13	specific	specific	JJ
cord-315781-dejh8q22	66	14	antibody	antibody	NN
cord-315781-dejh8q22	66	15	defenses	defense	NNS
cord-315781-dejh8q22	66	16	1	1	CD
cord-315781-dejh8q22	66	17	,	,	,
cord-315781-dejh8q22	66	18	humans	human	NNS
cord-315781-dejh8q22	66	19	have	have	VBP
cord-315781-dejh8q22	66	20	various	various	JJ
cord-315781-dejh8q22	66	21	antibodies	antibody	NNS
cord-315781-dejh8q22	66	22	that	that	WDT
cord-315781-dejh8q22	66	23	target	target	VBP
cord-315781-dejh8q22	66	24	different	different	JJ
cord-315781-dejh8q22	66	25	epitopes	epitope	NNS
cord-315781-dejh8q22	66	26	.	.	.
cord-315781-dejh8q22	67	1	The	the	DT
cord-315781-dejh8q22	67	2	drifts	drift	NNS
cord-315781-dejh8q22	67	3	that	that	WDT
cord-315781-dejh8q22	67	4	occur	occur	VBP
cord-315781-dejh8q22	67	5	within	within	IN
cord-315781-dejh8q22	67	6	a	a	DT
cord-315781-dejh8q22	67	7	year	year	NN
cord-315781-dejh8q22	67	8	would	would	MD
cord-315781-dejh8q22	67	9	be	be	VB
cord-315781-dejh8q22	67	10	insufficient	insufficient	JJ
cord-315781-dejh8q22	67	11	for	for	IN
cord-315781-dejh8q22	67	12	viral	viral	JJ
cord-315781-dejh8q22	67	13	spread	spread	NN
cord-315781-dejh8q22	67	14	in	in	IN
cord-315781-dejh8q22	67	15	the	the	DT
cord-315781-dejh8q22	67	16	same	same	JJ
cord-315781-dejh8q22	67	17	district	district	NN
cord-315781-dejh8q22	67	18	;	;	:
cord-315781-dejh8q22	67	19	hence	hence	RB
cord-315781-dejh8q22	67	20	,	,	,
cord-315781-dejh8q22	67	21	H1	h1	NN
cord-315781-dejh8q22	67	22	outbreaks	outbreak	NNS
cord-315781-dejh8q22	67	23	occurring	occur	VBG
cord-315781-dejh8q22	67	24	in	in	IN
cord-315781-dejh8q22	67	25	two	two	CD
cord-315781-dejh8q22	67	26	consecutive	consecutive	JJ
cord-315781-dejh8q22	67	27	years	year	NNS
cord-315781-dejh8q22	67	28	were	be	VBD
cord-315781-dejh8q22	67	29	rare	rare	JJ
cord-315781-dejh8q22	67	30	(	(	-LRB-
cord-315781-dejh8q22	67	31	Figs	fig	NNS
cord-315781-dejh8q22	67	32	.	.	.
cord-315781-dejh8q22	68	1	2D	2D	NNP
cord-315781-dejh8q22	68	2	and	and	CC
cord-315781-dejh8q22	68	3	S5	S5	NNP
cord-315781-dejh8q22	68	4	)	)	-RRB-
cord-315781-dejh8q22	68	5	.	.	.
cord-315781-dejh8q22	69	1	Thus	thus	RB
cord-315781-dejh8q22	69	2	,	,	,
cord-315781-dejh8q22	69	3	the	the	DT
cord-315781-dejh8q22	69	4	areas	area	NNS
cord-315781-dejh8q22	69	5	that	that	WDT
cord-315781-dejh8q22	69	6	record	record	VBP
cord-315781-dejh8q22	69	7	an	an	DT
cord-315781-dejh8q22	69	8	outbreak	outbreak	NN
cord-315781-dejh8q22	69	9	change	change	NN
cord-315781-dejh8q22	69	10	yearly	yearly	JJ
cord-315781-dejh8q22	69	11	(	(	-LRB-
cord-315781-dejh8q22	69	12	Fig	fig	NN
cord-315781-dejh8q22	69	13	.	.	.
cord-315781-dejh8q22	69	14	S5	S5	NNP
cord-315781-dejh8q22	69	15	)	)	-RRB-
cord-315781-dejh8q22	69	16	.	.	.
cord-315781-dejh8q22	70	1	The	the	DT
cord-315781-dejh8q22	70	2	axis	axis	NN
cord-315781-dejh8q22	70	3	of	of	IN
cord-315781-dejh8q22	70	4	PC1	PC1	NNP
cord-315781-dejh8q22	70	5	exhibited	exhibit	VBD
cord-315781-dejh8q22	70	6	contributions	contribution	NNS
cord-315781-dejh8q22	70	7	from	from	IN
cord-315781-dejh8q22	70	8	bases	basis	NNS
cord-315781-dejh8q22	70	9	that	that	WDT
cord-315781-dejh8q22	70	10	changed	change	VBD
cord-315781-dejh8q22	70	11	once	once	RB
cord-315781-dejh8q22	70	12	,	,	,
cord-315781-dejh8q22	70	13	whereas	whereas	IN
cord-315781-dejh8q22	70	14	PC2	PC2	NNP
cord-315781-dejh8q22	70	15	was	be	VBD
cord-315781-dejh8q22	70	16	characterized	characterize	VBN
cord-315781-dejh8q22	70	17	by	by	IN
cord-315781-dejh8q22	70	18	bases	basis	NNS
cord-315781-dejh8q22	70	19	that	that	WDT
cord-315781-dejh8q22	70	20	changed	change	VBD
cord-315781-dejh8q22	70	21	back	back	RB
cord-315781-dejh8q22	70	22	and	and	CC
cord-315781-dejh8q22	70	23	forth	forth	RB
cord-315781-dejh8q22	70	24	(	(	-LRB-
cord-315781-dejh8q22	70	25	Fig	fig	NN
cord-315781-dejh8q22	70	26	.	.	.
cord-315781-dejh8q22	71	1	S4A	S4A	NNP
cord-315781-dejh8q22	71	2	)	)	-RRB-
cord-315781-dejh8q22	71	3	.	.	.
cord-315781-dejh8q22	72	1	This	this	DT
cord-315781-dejh8q22	72	2	oscillation	oscillation	NN
cord-315781-dejh8q22	72	3	might	may	MD
cord-315781-dejh8q22	72	4	have	have	VB
cord-315781-dejh8q22	72	5	been	be	VBN
cord-315781-dejh8q22	72	6	caused	cause	VBN
cord-315781-dejh8q22	72	7	by	by	IN
cord-315781-dejh8q22	72	8	sequential	sequential	JJ
cord-315781-dejh8q22	72	9	random	random	JJ
cord-315781-dejh8q22	72	10	walk	walk	NN
cord-315781-dejh8q22	72	11	mutation	mutation	NN
cord-315781-dejh8q22	72	12	6	6	CD
cord-315781-dejh8q22	72	13	.	.	.
cord-315781-dejh8q22	73	1	The	the	DT
cord-315781-dejh8q22	73	2	random	random	JJ
cord-315781-dejh8q22	73	3	walk	walk	NN
cord-315781-dejh8q22	73	4	model	model	NN
cord-315781-dejh8q22	73	5	was	be	VBD
cord-315781-dejh8q22	73	6	also	also	RB
cord-315781-dejh8q22	73	7	supported	support	VBN
cord-315781-dejh8q22	73	8	by	by	IN
cord-315781-dejh8q22	73	9	the	the	DT
cord-315781-dejh8q22	73	10	rapid	rapid	JJ
cord-315781-dejh8q22	73	11	attenuation	attenuation	NN
cord-315781-dejh8q22	73	12	of	of	IN
cord-315781-dejh8q22	73	13	the	the	DT
cord-315781-dejh8q22	73	14	contributions	contribution	NNS
cord-315781-dejh8q22	73	15	and	and	CC
cord-315781-dejh8q22	73	16	the	the	DT
cord-315781-dejh8q22	73	17	accordance	accordance	NN
cord-315781-dejh8q22	73	18	with	with	IN
cord-315781-dejh8q22	73	19	the	the	DT
cord-315781-dejh8q22	73	20	tangent	tangent	JJ
cord-315781-dejh8q22	73	21	rule	rule	NN
cord-315781-dejh8q22	73	22	(	(	-LRB-
cord-315781-dejh8q22	73	23	Fig	Fig	NNP
cord-315781-dejh8q22	73	24	.	.	.
cord-315781-dejh8q22	73	25	S4	S4	NNP
cord-315781-dejh8q22	73	26	)	)	-RRB-
cord-315781-dejh8q22	73	27	6	6	CD
cord-315781-dejh8q22	73	28	.	.	.
cord-315781-dejh8q22	74	1	However	however	RB
cord-315781-dejh8q22	74	2	,	,	,
cord-315781-dejh8q22	74	3	a	a	DT
cord-315781-dejh8q22	74	4	constant	constant	JJ
cord-315781-dejh8q22	74	5	pattern	pattern	NN
cord-315781-dejh8q22	74	6	of	of	IN
cord-315781-dejh8q22	74	7	oscillation	oscillation	NN
cord-315781-dejh8q22	74	8	did	do	VBD
cord-315781-dejh8q22	74	9	not	not	RB
cord-315781-dejh8q22	74	10	appear	appear	VB
cord-315781-dejh8q22	74	11	in	in	IN
cord-315781-dejh8q22	74	12	lower	low	JJR
cord-315781-dejh8q22	74	13	-	-	HYPH
cord-315781-dejh8q22	74	14	level	level	NN
cord-315781-dejh8q22	74	15	PCs	pc	NNS
cord-315781-dejh8q22	74	16	,	,	,
cord-315781-dejh8q22	74	17	suggesting	suggest	VBG
cord-315781-dejh8q22	74	18	that	that	IN
cord-315781-dejh8q22	74	19	the	the	DT
cord-315781-dejh8q22	74	20	changes	change	NNS
cord-315781-dejh8q22	74	21	were	be	VBD
cord-315781-dejh8q22	74	22	not	not	RB
cord-315781-dejh8q22	74	23	fully	fully	RB
cord-315781-dejh8q22	74	24	random	random	JJ
cord-315781-dejh8q22	74	25	;	;	:
cord-315781-dejh8q22	74	26	rather	rather	RB
cord-315781-dejh8q22	74	27	,	,	,
cord-315781-dejh8q22	74	28	they	-PRON-	PRP
cord-315781-dejh8q22	74	29	seemed	seem	VBD
cord-315781-dejh8q22	74	30	to	to	TO
cord-315781-dejh8q22	74	31	obey	obey	VB
cord-315781-dejh8q22	74	32	some	some	DT
cord-315781-dejh8q22	74	33	unidentified	unidentified	JJ
cord-315781-dejh8q22	74	34	rules	rule	NNS
cord-315781-dejh8q22	74	35	.	.	.
cord-315781-dejh8q22	75	1	As	as	IN
cord-315781-dejh8q22	75	2	the	the	DT
cord-315781-dejh8q22	75	3	number	number	NN
cord-315781-dejh8q22	75	4	of	of	IN
cord-315781-dejh8q22	75	5	samples	sample	NNS
cord-315781-dejh8q22	75	6	is	be	VBZ
cord-315781-dejh8q22	75	7	much	much	RB
cord-315781-dejh8q22	75	8	smaller	small	JJR
cord-315781-dejh8q22	75	9	than	than	IN
cord-315781-dejh8q22	75	10	the	the	DT
cord-315781-dejh8q22	75	11	number	number	NN
cord-315781-dejh8q22	75	12	of	of	IN
cord-315781-dejh8q22	75	13	bases	basis	NNS
cord-315781-dejh8q22	75	14	,	,	,
cord-315781-dejh8q22	75	15	the	the	DT
cord-315781-dejh8q22	75	16	dimension	dimension	NN
cord-315781-dejh8q22	75	17	of	of	IN
cord-315781-dejh8q22	75	18	the	the	DT
cord-315781-dejh8q22	75	19	PCA	PCA	NNP
cord-315781-dejh8q22	75	20	is	be	VBZ
cord-315781-dejh8q22	75	21	determined	determine	VBN
cord-315781-dejh8q22	75	22	by	by	IN
cord-315781-dejh8q22	75	23	the	the	DT
cord-315781-dejh8q22	75	24	samples	sample	NNS
cord-315781-dejh8q22	75	25	.	.	.
cord-315781-dejh8q22	76	1	In	in	IN
cord-315781-dejh8q22	76	2	particular	particular	JJ
cord-315781-dejh8q22	76	3	,	,	,
cord-315781-dejh8q22	76	4	as	as	IN
cord-315781-dejh8q22	76	5	the	the	DT
cord-315781-dejh8q22	76	6	samples	sample	NNS
cord-315781-dejh8q22	76	7	do	do	VBP
cord-315781-dejh8q22	76	8	not	not	RB
cord-315781-dejh8q22	76	9	differ	differ	VB
cord-315781-dejh8q22	76	10	much	much	RB
cord-315781-dejh8q22	76	11	within	within	IN
cord-315781-dejh8q22	76	12	a	a	DT
cord-315781-dejh8q22	76	13	year	year	NN
cord-315781-dejh8q22	76	14	,	,	,
cord-315781-dejh8q22	76	15	the	the	DT
cord-315781-dejh8q22	76	16	actual	actual	JJ
cord-315781-dejh8q22	76	17	dimension	dimension	NN
cord-315781-dejh8q22	76	18	is	be	VBZ
cord-315781-dejh8q22	76	19	determined	determine	VBN
cord-315781-dejh8q22	76	20	by	by	IN
cord-315781-dejh8q22	76	21	the	the	DT
cord-315781-dejh8q22	76	22	total	total	JJ
cord-315781-dejh8q22	76	23	number	number	NN
cord-315781-dejh8q22	76	24	of	of	IN
cord-315781-dejh8q22	76	25	years	year	NNS
cord-315781-dejh8q22	76	26	,	,	,
cord-315781-dejh8q22	76	27	forming	form	VBG
cord-315781-dejh8q22	76	28	the	the	DT
cord-315781-dejh8q22	76	29	drops	drop	NNS
cord-315781-dejh8q22	76	30	at	at	IN
cord-315781-dejh8q22	76	31	the	the	DT
cord-315781-dejh8q22	76	32	end	end	NN
cord-315781-dejh8q22	76	33	of	of	IN
cord-315781-dejh8q22	76	34	the	the	DT
cord-315781-dejh8q22	76	35	contributions	contribution	NNS
cord-315781-dejh8q22	76	36	;	;	:
cord-315781-dejh8q22	76	37	this	this	DT
cord-315781-dejh8q22	76	38	also	also	RB
cord-315781-dejh8q22	76	39	bends	bend	VBZ
cord-315781-dejh8q22	76	40	the	the	DT
cord-315781-dejh8q22	76	41	tangent	tangent	JJ
cord-315781-dejh8q22	76	42	regression	regression	NN
cord-315781-dejh8q22	76	43	at	at	IN
cord-315781-dejh8q22	76	44	its	-PRON-	PRP$
cord-315781-dejh8q22	76	45	lowest	low	JJS
cord-315781-dejh8q22	76	46	part	part	NN
cord-315781-dejh8q22	76	47	(	(	-LRB-
cord-315781-dejh8q22	76	48	Fig	Fig	NNP
cord-315781-dejh8q22	76	49	.	.	.
cord-315781-dejh8q22	76	50	S4	S4	NNP
cord-315781-dejh8q22	76	51	)	)	-RRB-
cord-315781-dejh8q22	76	52	.	.	.
cord-315781-dejh8q22	77	1	In	in	IN
cord-315781-dejh8q22	77	2	addition	addition	NN
cord-315781-dejh8q22	77	3	to	to	IN
cord-315781-dejh8q22	77	4	the	the	DT
cord-315781-dejh8q22	77	5	annual	annual	JJ
cord-315781-dejh8q22	77	6	continuous	continuous	JJ
cord-315781-dejh8q22	77	7	drifts	drift	NNS
cord-315781-dejh8q22	77	8	,	,	,
cord-315781-dejh8q22	77	9	several	several	JJ
cord-315781-dejh8q22	77	10	leaps	leap	NNS
cord-315781-dejh8q22	77	11	were	be	VBD
cord-315781-dejh8q22	77	12	also	also	RB
cord-315781-dejh8q22	77	13	observed	observe	VBN
cord-315781-dejh8q22	77	14	(	(	-LRB-
cord-315781-dejh8q22	77	15	Fig	Fig	NNP
cord-315781-dejh8q22	77	16	.	.	.
cord-315781-dejh8q22	77	17	2C	2C	NNP
cord-315781-dejh8q22	77	18	,	,	,
cord-315781-dejh8q22	77	19	arrows	arrow	NNS
cord-315781-dejh8q22	77	20	between	between	IN
cord-315781-dejh8q22	77	21	different	different	JJ
cord-315781-dejh8q22	77	22	colours	colour	NNS
cord-315781-dejh8q22	77	23	)	)	-RRB-
cord-315781-dejh8q22	77	24	.	.	.
cord-315781-dejh8q22	78	1	For	for	IN
cord-315781-dejh8q22	78	2	example	example	NN
cord-315781-dejh8q22	78	3	,	,	,
cord-315781-dejh8q22	78	4	variants	variant	NNS
cord-315781-dejh8q22	78	5	coloured	colour	VBN
cord-315781-dejh8q22	78	6	in	in	IN
cord-315781-dejh8q22	78	7	blue	blue	NNP
cord-315781-dejh8q22	78	8	started	start	VBD
cord-315781-dejh8q22	78	9	in	in	IN
cord-315781-dejh8q22	78	10	1985	1985	CD
cord-315781-dejh8q22	78	11	,	,	,
cord-315781-dejh8q22	78	12	kept	keep	VBD
cord-315781-dejh8q22	78	13	drifting	drift	VBG
cord-315781-dejh8q22	78	14	,	,	,
cord-315781-dejh8q22	78	15	and	and	CC
cord-315781-dejh8q22	78	16	were	be	VBD
cord-315781-dejh8q22	78	17	recorded	record	VBN
cord-315781-dejh8q22	78	18	through	through	IN
cord-315781-dejh8q22	78	19	to	to	IN
cord-315781-dejh8q22	78	20	2001	2001	CD
cord-315781-dejh8q22	78	21	,	,	,
cord-315781-dejh8q22	78	22	going	go	VBG
cord-315781-dejh8q22	78	23	around	around	IN
cord-315781-dejh8q22	78	24	the	the	DT
cord-315781-dejh8q22	78	25	world	world	NN
cord-315781-dejh8q22	78	26	several	several	JJ
cord-315781-dejh8q22	78	27	times	time	NNS
cord-315781-dejh8q22	78	28	.	.	.
cord-315781-dejh8q22	79	1	Those	those	DT
cord-315781-dejh8q22	79	2	coloured	coloured	JJ
cord-315781-dejh8q22	79	3	in	in	IN
cord-315781-dejh8q22	79	4	black	black	JJ
cord-315781-dejh8q22	79	5	were	be	VBD
cord-315781-dejh8q22	79	6	found	find	VBN
cord-315781-dejh8q22	79	7	in	in	IN
cord-315781-dejh8q22	79	8	1995	1995	CD
cord-315781-dejh8q22	79	9	and	and	CC
cord-315781-dejh8q22	79	10	were	be	VBD
cord-315781-dejh8q22	79	11	recorded	record	VBN
cord-315781-dejh8q22	79	12	through	through	IN
cord-315781-dejh8q22	79	13	to	to	IN
cord-315781-dejh8q22	79	14	2007	2007	CD
cord-315781-dejh8q22	79	15	.	.	.
cord-315781-dejh8q22	80	1	Those	those	DT
cord-315781-dejh8q22	80	2	in	in	IN
cord-315781-dejh8q22	80	3	grey	grey	NN
cord-315781-dejh8q22	80	4	did	do	VBD
cord-315781-dejh8q22	80	5	not	not	RB
cord-315781-dejh8q22	80	6	change	change	VB
cord-315781-dejh8q22	80	7	in	in	IN
cord-315781-dejh8q22	80	8	PC1	PC1	NNP
cord-315781-dejh8q22	80	9	,	,	,
cord-315781-dejh8q22	80	10	but	but	CC
cord-315781-dejh8q22	80	11	they	-PRON-	PRP
cord-315781-dejh8q22	80	12	went	go	VBD
cord-315781-dejh8q22	80	13	back	back	RB
cord-315781-dejh8q22	80	14	toward	toward	IN
cord-315781-dejh8q22	80	15	the	the	DT
cord-315781-dejh8q22	80	16	PC2	PC2	NNP
cord-315781-dejh8q22	80	17	axis	axis	NN
cord-315781-dejh8q22	80	18	(	(	-LRB-
cord-315781-dejh8q22	80	19	other	other	JJ
cord-315781-dejh8q22	80	20	directions	direction	NNS
cord-315781-dejh8q22	80	21	also	also	RB
cord-315781-dejh8q22	80	22	appeared	appear	VBD
cord-315781-dejh8q22	80	23	in	in	IN
cord-315781-dejh8q22	80	24	lower	low	JJR
cord-315781-dejh8q22	80	25	PCs	pc	NNS
cord-315781-dejh8q22	80	26	,	,	,
cord-315781-dejh8q22	80	27	with	with	IN
cord-315781-dejh8q22	80	28	contributions	contribution	NNS
cord-315781-dejh8q22	80	29	from	from	IN
cord-315781-dejh8q22	80	30	positions	position	NNS
cord-315781-dejh8q22	80	31	that	that	WDT
cord-315781-dejh8q22	80	32	changed	change	VBD
cord-315781-dejh8q22	80	33	several	several	JJ
cord-315781-dejh8q22	80	34	times	time	NNS
cord-315781-dejh8q22	80	35	;	;	:
cord-315781-dejh8q22	80	36	Fig	Fig	NNP
cord-315781-dejh8q22	80	37	.	.	.
cord-315781-dejh8q22	81	1	S4A	S4A	NNP
cord-315781-dejh8q22	81	2	)	)	-RRB-
cord-315781-dejh8q22	81	3	.	.	.
cord-315781-dejh8q22	82	1	The	the	DT
cord-315781-dejh8q22	82	2	leaps	leap	NNS
cord-315781-dejh8q22	82	3	would	would	MD
cord-315781-dejh8q22	82	4	refresh	refresh	VB
cord-315781-dejh8q22	82	5	the	the	DT
cord-315781-dejh8q22	82	6	character	character	NN
cord-315781-dejh8q22	82	7	of	of	IN
cord-315781-dejh8q22	82	8	the	the	DT
cord-315781-dejh8q22	82	9	epitopes	epitope	NNS
cord-315781-dejh8q22	82	10	;	;	,
cord-315781-dejh8q22	82	11	e.g.	e.g.	RB
cord-315781-dejh8q22	82	12	,	,	,
cord-315781-dejh8q22	82	13	the	the	DT
cord-315781-dejh8q22	82	14	black	black	JJ
cord-315781-dejh8q22	82	15	leap	leap	NN
cord-315781-dejh8q22	82	16	might	may	MD
cord-315781-dejh8q22	82	17	allow	allow	VB
cord-315781-dejh8q22	82	18	the	the	DT
cord-315781-dejh8q22	82	19	parallel	parallel	JJ
cord-315781-dejh8q22	82	20	evolution	evolution	NN
cord-315781-dejh8q22	82	21	of	of	IN
cord-315781-dejh8q22	82	22	the	the	DT
cord-315781-dejh8q22	82	23	blue	blue	JJ
cord-315781-dejh8q22	82	24	and	and	CC
cord-315781-dejh8q22	82	25	black	black	JJ
cord-315781-dejh8q22	82	26	variants	variant	NNS
cord-315781-dejh8q22	82	27	detected	detect	VBN
cord-315781-dejh8q22	82	28	in	in	IN
cord-315781-dejh8q22	82	29	PC4	pc4	NN
cord-315781-dejh8q22	82	30	(	(	-LRB-
cord-315781-dejh8q22	82	31	Fig	Fig	NNP
cord-315781-dejh8q22	82	32	.	.	.
cord-315781-dejh8q22	82	33	2B	2b	CD
cord-315781-dejh8q22	82	34	)	)	-RRB-
cord-315781-dejh8q22	82	35	.	.	.
cord-315781-dejh8q22	83	1	The	the	DT
cord-315781-dejh8q22	83	2	leaps	leap	NNS
cord-315781-dejh8q22	83	3	seemed	seem	VBD
cord-315781-dejh8q22	83	4	to	to	TO
cord-315781-dejh8q22	83	5	occur	occur	VB
cord-315781-dejh8q22	83	6	during	during	IN
cord-315781-dejh8q22	83	7	the	the	DT
cord-315781-dejh8q22	83	8	years	year	NNS
cord-315781-dejh8q22	83	9	in	in	IN
cord-315781-dejh8q22	83	10	which	which	WDT
cord-315781-dejh8q22	83	11	the	the	DT
cord-315781-dejh8q22	83	12	viruses	virus	NNS
cord-315781-dejh8q22	83	13	were	be	VBD
cord-315781-dejh8q22	83	14	not	not	RB
cord-315781-dejh8q22	83	15	detected	detect	VBN
cord-315781-dejh8q22	83	16	in	in	IN
cord-315781-dejh8q22	83	17	the	the	DT
cord-315781-dejh8q22	83	18	areas	area	NNS
cord-315781-dejh8q22	83	19	that	that	WDT
cord-315781-dejh8q22	83	20	reported	report	VBD
cord-315781-dejh8q22	83	21	the	the	DT
cord-315781-dejh8q22	83	22	surveillance	surveillance	NN
cord-315781-dejh8q22	83	23	viral	viral	JJ
cord-315781-dejh8q22	83	24	counts	count	NNS
cord-315781-dejh8q22	83	25	and	and	CC
cord-315781-dejh8q22	83	26	sequences	sequence	NNS
cord-315781-dejh8q22	83	27	(	(	-LRB-
cord-315781-dejh8q22	83	28	Figs	fig	NNS
cord-315781-dejh8q22	83	29	.	.	.
cord-315781-dejh8q22	84	1	2D	2D	NNP
cord-315781-dejh8q22	84	2	and	and	CC
cord-315781-dejh8q22	84	3	S5	S5	NNP
cord-315781-dejh8q22	84	4	)	)	-RRB-
cord-315781-dejh8q22	84	5	.	.	.
cord-315781-dejh8q22	85	1	Leaps	leap	NNS
cord-315781-dejh8q22	85	2	were	be	VBD
cord-315781-dejh8q22	85	3	also	also	RB
cord-315781-dejh8q22	85	4	observed	observe	VBN
cord-315781-dejh8q22	85	5	in	in	IN
cord-315781-dejh8q22	85	6	other	other	JJ
cord-315781-dejh8q22	85	7	segments	segment	NNS
cord-315781-dejh8q22	85	8	;	;	:
cord-315781-dejh8q22	85	9	although	although	IN
cord-315781-dejh8q22	85	10	the	the	DT
cord-315781-dejh8q22	85	11	distance	distance	NN
cord-315781-dejh8q22	85	12	of	of	IN
cord-315781-dejh8q22	85	13	jumps	jump	NNS
cord-315781-dejh8q22	85	14	may	may	MD
cord-315781-dejh8q22	85	15	have	have	VB
cord-315781-dejh8q22	85	16	exhibited	exhibit	VBN
cord-315781-dejh8q22	85	17	a	a	DT
cord-315781-dejh8q22	85	18	certain	certain	JJ
cord-315781-dejh8q22	85	19	variation	variation	NN
cord-315781-dejh8q22	85	20	,	,	,
cord-315781-dejh8q22	85	21	their	-PRON-	PRP$
cord-315781-dejh8q22	85	22	timing	timing	NN
cord-315781-dejh8q22	85	23	was	be	VBD
cord-315781-dejh8q22	85	24	similar	similar	JJ
cord-315781-dejh8q22	85	25	,	,	,
cord-315781-dejh8q22	85	26	and	and	CC
cord-315781-dejh8q22	85	27	the	the	DT
cord-315781-dejh8q22	85	28	relationships	relationship	NNS
cord-315781-dejh8q22	85	29	among	among	IN
cord-315781-dejh8q22	85	30	the	the	DT
cord-315781-dejh8q22	85	31	segments	segment	NNS
cord-315781-dejh8q22	85	32	that	that	WDT
cord-315781-dejh8q22	85	33	appeared	appear	VBD
cord-315781-dejh8q22	85	34	in	in	IN
cord-315781-dejh8q22	85	35	PC1	PC1	NNP
cord-315781-dejh8q22	85	36	and	and	CC
cord-315781-dejh8q22	85	37	PC2	PC2	NNP
cord-315781-dejh8q22	85	38	were	be	VBD
cord-315781-dejh8q22	85	39	all	all	DT
cord-315781-dejh8q22	85	40	lambda	lambda	NN
cord-315781-dejh8q22	85	41	shaped	shape	VBN
cord-315781-dejh8q22	85	42	,	,	,
cord-315781-dejh8q22	85	43	pointing	point	VBG
cord-315781-dejh8q22	85	44	to	to	IN
cord-315781-dejh8q22	85	45	the	the	DT
cord-315781-dejh8q22	85	46	three	three	CD
cord-315781-dejh8q22	85	47	terminals	terminal	NNS
cord-315781-dejh8q22	85	48	(	(	-LRB-
cord-315781-dejh8q22	85	49	Fig	fig	NN
cord-315781-dejh8q22	85	50	.	.	.
cord-315781-dejh8q22	85	51	S6	S6	NNP
cord-315781-dejh8q22	85	52	)	)	-RRB-
cord-315781-dejh8q22	85	53	.	.	.
cord-315781-dejh8q22	86	1	The	the	DT
cord-315781-dejh8q22	86	2	magnitude	magnitude	NN
cord-315781-dejh8q22	86	3	of	of	IN
cord-315781-dejh8q22	86	4	the	the	DT
cord-315781-dejh8q22	86	5	differences	difference	NNS
cord-315781-dejh8q22	86	6	was	be	VBD
cord-315781-dejh8q22	86	7	very	very	RB
cord-315781-dejh8q22	86	8	similar	similar	JJ
cord-315781-dejh8q22	86	9	among	among	IN
cord-315781-dejh8q22	86	10	the	the	DT
cord-315781-dejh8q22	86	11	segments	segment	NNS
cord-315781-dejh8q22	86	12	,	,	,
cord-315781-dejh8q22	86	13	which	which	WDT
cord-315781-dejh8q22	86	14	suggests	suggest	VBZ
cord-315781-dejh8q22	86	15	the	the	DT
cord-315781-dejh8q22	86	16	presence	presence	NN
cord-315781-dejh8q22	86	17	of	of	IN
cord-315781-dejh8q22	86	18	a	a	DT
cord-315781-dejh8q22	86	19	constant	constant	JJ
cord-315781-dejh8q22	86	20	mutation	mutation	NN
cord-315781-dejh8q22	86	21	rate	rate	NN
cord-315781-dejh8q22	86	22	among	among	IN
cord-315781-dejh8q22	86	23	the	the	DT
cord-315781-dejh8q22	86	24	segments	segment	NNS
cord-315781-dejh8q22	86	25	.	.	.
cord-315781-dejh8q22	87	1	As	as	IN
cord-315781-dejh8q22	87	2	was	be	VBD
cord-315781-dejh8q22	87	3	the	the	DT
cord-315781-dejh8q22	87	4	case	case	NN
cord-315781-dejh8q22	87	5	for	for	IN
cord-315781-dejh8q22	87	6	the	the	DT
cord-315781-dejh8q22	87	7	H1	H1	NNP
cord-315781-dejh8q22	87	8	viruses	virus	NNS
cord-315781-dejh8q22	87	9	,	,	,
cord-315781-dejh8q22	87	10	the	the	DT
cord-315781-dejh8q22	87	11	changes	change	NNS
cord-315781-dejh8q22	87	12	seemed	seem	VBD
cord-315781-dejh8q22	87	13	to	to	TO
cord-315781-dejh8q22	87	14	be	be	VB
cord-315781-dejh8q22	87	15	a	a	DT
cord-315781-dejh8q22	87	16	choice	choice	NN
cord-315781-dejh8q22	87	17	between	between	IN
cord-315781-dejh8q22	87	18	two	two	CD
cord-315781-dejh8q22	87	19	amino	amino	NN
cord-315781-dejh8q22	87	20	acids	acid	NNS
cord-315781-dejh8q22	87	21	,	,	,
cord-315781-dejh8q22	87	22	each	each	DT
cord-315781-dejh8q22	87	23	of	of	IN
cord-315781-dejh8q22	87	24	which	which	WDT
cord-315781-dejh8q22	87	25	showed	show	VBD
cord-315781-dejh8q22	87	26	extreme	extreme	JJ
cord-315781-dejh8q22	87	27	positive	positive	JJ
cord-315781-dejh8q22	87	28	or	or	CC
cord-315781-dejh8q22	87	29	negative	negative	JJ
cord-315781-dejh8q22	87	30	values	value	NNS
cord-315781-dejh8q22	87	31	in	in	IN
cord-315781-dejh8q22	87	32	PC	pc	NN
cord-315781-dejh8q22	87	33	for	for	IN
cord-315781-dejh8q22	87	34	bases	basis	NNS
cord-315781-dejh8q22	87	35	;	;	:
cord-315781-dejh8q22	87	36	therefore	therefore	RB
cord-315781-dejh8q22	87	37	,	,	,
cord-315781-dejh8q22	87	38	the	the	DT
cord-315781-dejh8q22	87	39	directions	direction	NNS
cord-315781-dejh8q22	87	40	of	of	IN
cord-315781-dejh8q22	87	41	PCs	pc	NNS
cord-315781-dejh8q22	87	42	for	for	IN
cord-315781-dejh8q22	87	43	residues	residue	NNS
cord-315781-dejh8q22	87	44	ran	run	VBD
cord-315781-dejh8q22	87	45	through	through	IN
cord-315781-dejh8q22	87	46	the	the	DT
cord-315781-dejh8q22	87	47	origin	origin	NN
cord-315781-dejh8q22	87	48	,	,	,
cord-315781-dejh8q22	87	49	showing	show	VBG
cord-315781-dejh8q22	87	50	a	a	DT
cord-315781-dejh8q22	87	51	symmetrical	symmetrical	JJ
cord-315781-dejh8q22	87	52	hexagonal	hexagonal	JJ
cord-315781-dejh8q22	87	53	shape	shape	NN
cord-315781-dejh8q22	87	54	in	in	IN
cord-315781-dejh8q22	87	55	HA	HA	NNP
cord-315781-dejh8q22	87	56	(	(	-LRB-
cord-315781-dejh8q22	87	57	Fig	fig	NN
cord-315781-dejh8q22	87	58	.	.	.
cord-315781-dejh8q22	88	1	S1F	s1f	LS
cord-315781-dejh8q22	88	2	)	)	-RRB-
cord-315781-dejh8q22	88	3	.	.	.
cord-315781-dejh8q22	89	1	The	the	DT
cord-315781-dejh8q22	89	2	variation	variation	NN
cord-315781-dejh8q22	89	3	of	of	IN
cord-315781-dejh8q22	89	4	permissive	permissive	JJ
cord-315781-dejh8q22	89	5	amino	amino	NN
cord-315781-dejh8q22	89	6	acids	acid	NNS
cord-315781-dejh8q22	89	7	should	should	MD
cord-315781-dejh8q22	89	8	be	be	VB
cord-315781-dejh8q22	89	9	limited	limit	VBN
cord-315781-dejh8q22	89	10	at	at	IN
cord-315781-dejh8q22	89	11	each	each	DT
cord-315781-dejh8q22	89	12	position	position	NN
cord-315781-dejh8q22	89	13	.	.	.
cord-315781-dejh8q22	90	1	Livestock	livestock	NN
cord-315781-dejh8q22	90	2	viruses	virus	NNS
cord-315781-dejh8q22	90	3	.	.	.
cord-315781-dejh8q22	91	1	Let	let	VB
cord-315781-dejh8q22	91	2	us	-PRON-	PRP
cord-315781-dejh8q22	91	3	consider	consider	VB
cord-315781-dejh8q22	91	4	the	the	DT
cord-315781-dejh8q22	91	5	annual	annual	JJ
cord-315781-dejh8q22	91	6	changes	change	NNS
cord-315781-dejh8q22	91	7	among	among	IN
cord-315781-dejh8q22	91	8	the	the	DT
cord-315781-dejh8q22	91	9	viruses	virus	NNS
cord-315781-dejh8q22	91	10	of	of	IN
cord-315781-dejh8q22	91	11	livestock	livestock	NN
cord-315781-dejh8q22	91	12	(	(	-LRB-
cord-315781-dejh8q22	91	13	swine	swine	NN
cord-315781-dejh8q22	91	14	H1	h1	NN
cord-315781-dejh8q22	91	15	:	:	:
cord-315781-dejh8q22	91	16	Fig	fig	NN
cord-315781-dejh8q22	91	17	.	.	.
cord-315781-dejh8q22	92	1	S4B	S4B	NNS
cord-315781-dejh8q22	92	2	;	;	,
cord-315781-dejh8q22	92	3	chicken	chicken	NN
cord-315781-dejh8q22	92	4	H5	h5	NN
cord-315781-dejh8q22	92	5	:	:	:
cord-315781-dejh8q22	92	6	Fig	Fig	NNP
cord-315781-dejh8q22	92	7	.	.	.
cord-315781-dejh8q22	92	8	S4C	s4c	NN
cord-315781-dejh8q22	92	9	)	)	-RRB-
cord-315781-dejh8q22	92	10	.	.	.
cord-315781-dejh8q22	93	1	Many	many	JJ
cord-315781-dejh8q22	93	2	variations	variation	NNS
cord-315781-dejh8q22	93	3	were	be	VBD
cord-315781-dejh8q22	93	4	present	present	JJ
cord-315781-dejh8q22	93	5	coincidently	coincidently	RB
cord-315781-dejh8q22	93	6	in	in	IN
cord-315781-dejh8q22	93	7	any	any	DT
cord-315781-dejh8q22	93	8	given	give	VBN
cord-315781-dejh8q22	93	9	year	year	NN
cord-315781-dejh8q22	93	10	,	,	,
cord-315781-dejh8q22	93	11	especially	especially	RB
cord-315781-dejh8q22	93	12	in	in	IN
cord-315781-dejh8q22	93	13	recent	recent	JJ
cord-315781-dejh8q22	93	14	years	year	NNS
cord-315781-dejh8q22	93	15	,	,	,
cord-315781-dejh8q22	93	16	when	when	WRB
cord-315781-dejh8q22	93	17	the	the	DT
cord-315781-dejh8q22	93	18	sequences	sequence	NNS
cord-315781-dejh8q22	93	19	became	become	VBD
cord-315781-dejh8q22	93	20	available	available	JJ
cord-315781-dejh8q22	93	21	from	from	IN
cord-315781-dejh8q22	93	22	various	various	JJ
cord-315781-dejh8q22	93	23	areas	area	NNS
cord-315781-dejh8q22	93	24	.	.	.
cord-315781-dejh8q22	94	1	Such	such	PDT
cord-315781-dejh8q22	94	2	a	a	DT
cord-315781-dejh8q22	94	3	variety	variety	NN
cord-315781-dejh8q22	94	4	may	may	MD
cord-315781-dejh8q22	94	5	hide	hide	VB
cord-315781-dejh8q22	94	6	the	the	DT
cord-315781-dejh8q22	94	7	effects	effect	NNS
cord-315781-dejh8q22	94	8	of	of	IN
cord-315781-dejh8q22	94	9	drifts	drift	NNS
cord-315781-dejh8q22	94	10	from	from	IN
cord-315781-dejh8q22	94	11	higher	high	JJR
cord-315781-dejh8q22	94	12	axes	axis	NNS
cord-315781-dejh8q22	94	13	of	of	IN
cord-315781-dejh8q22	94	14	the	the	DT
cord-315781-dejh8q22	94	15	PCA	PCA	NNP
cord-315781-dejh8q22	94	16	.	.	.
cord-315781-dejh8q22	95	1	In	in	IN
cord-315781-dejh8q22	95	2	fact	fact	NN
cord-315781-dejh8q22	95	3	,	,	,
cord-315781-dejh8q22	95	4	the	the	DT
cord-315781-dejh8q22	95	5	PC	pc	NN
cord-315781-dejh8q22	95	6	values	value	NNS
cord-315781-dejh8q22	95	7	formed	form	VBD
cord-315781-dejh8q22	95	8	horizontal	horizontal	JJ
cord-315781-dejh8q22	95	9	rows	row	NNS
cord-315781-dejh8q22	95	10	in	in	IN
cord-315781-dejh8q22	95	11	the	the	DT
cord-315781-dejh8q22	95	12	plots	plot	NNS
cord-315781-dejh8q22	95	13	.	.	.
cord-315781-dejh8q22	96	1	However	however	RB
cord-315781-dejh8q22	96	2	,	,	,
cord-315781-dejh8q22	96	3	the	the	DT
cord-315781-dejh8q22	96	4	variations	variation	NNS
cord-315781-dejh8q22	96	5	detected	detect	VBN
cord-315781-dejh8q22	96	6	in	in	IN
cord-315781-dejh8q22	96	7	an	an	DT
cord-315781-dejh8q22	96	8	area	area	NN
cord-315781-dejh8q22	96	9	did	do	VBD
cord-315781-dejh8q22	96	10	not	not	RB
cord-315781-dejh8q22	96	11	change	change	VB
cord-315781-dejh8q22	96	12	much	much	RB
cord-315781-dejh8q22	96	13	,	,	,
cord-315781-dejh8q22	96	14	even	even	RB
cord-315781-dejh8q22	96	15	in	in	IN
cord-315781-dejh8q22	96	16	lower	low	JJR
cord-315781-dejh8q22	96	17	PC	pc	NN
cord-315781-dejh8q22	96	18	axes	axis	NNS
cord-315781-dejh8q22	96	19	(	(	-LRB-
cord-315781-dejh8q22	96	20	Fig	fig	NN
cord-315781-dejh8q22	96	21	.	.	.
cord-315781-dejh8q22	97	1	S4B	S4B	NNP
cord-315781-dejh8q22	97	2	,	,	,
cord-315781-dejh8q22	97	3	C	C	NNP
cord-315781-dejh8q22	97	4	)	)	-RRB-
cord-315781-dejh8q22	97	5	.	.	.
cord-315781-dejh8q22	98	1	The	the	DT
cord-315781-dejh8q22	98	2	small	small	JJ
cord-315781-dejh8q22	98	3	changes	change	NNS
cord-315781-dejh8q22	98	4	may	may	MD
cord-315781-dejh8q22	98	5	result	result	VB
cord-315781-dejh8q22	98	6	from	from	IN
cord-315781-dejh8q22	98	7	differences	difference	NNS
cord-315781-dejh8q22	98	8	in	in	IN
cord-315781-dejh8q22	98	9	the	the	DT
cord-315781-dejh8q22	98	10	districts	district	NNS
cord-315781-dejh8q22	98	11	that	that	WDT
cord-315781-dejh8q22	98	12	were	be	VBD
cord-315781-dejh8q22	98	13	surveyed	survey	VBN
cord-315781-dejh8q22	98	14	in	in	IN
cord-315781-dejh8q22	98	15	specific	specific	JJ
cord-315781-dejh8q22	98	16	years	year	NNS
cord-315781-dejh8q22	98	17	,	,	,
cord-315781-dejh8q22	98	18	rather	rather	RB
cord-315781-dejh8q22	98	19	than	than	IN
cord-315781-dejh8q22	98	20	from	from	IN
cord-315781-dejh8q22	98	21	those	those	DT
cord-315781-dejh8q22	98	22	caused	cause	VBN
cord-315781-dejh8q22	98	23	by	by	IN
cord-315781-dejh8q22	98	24	drifts	drift	NNS
cord-315781-dejh8q22	98	25	.	.	.
cord-315781-dejh8q22	99	1	Moreover	moreover	RB
cord-315781-dejh8q22	99	2	,	,	,
cord-315781-dejh8q22	99	3	strains	strain	NNS
cord-315781-dejh8q22	99	4	that	that	WDT
cord-315781-dejh8q22	99	5	may	may	MD
cord-315781-dejh8q22	99	6	be	be	VB
cord-315781-dejh8q22	99	7	transmitted	transmit	VBN
cord-315781-dejh8q22	99	8	from	from	IN
cord-315781-dejh8q22	99	9	humans	human	NNS
cord-315781-dejh8q22	99	10	to	to	IN
cord-315781-dejh8q22	99	11	swine	swine	NNS
cord-315781-dejh8q22	99	12	were	be	VBD
cord-315781-dejh8q22	99	13	detected	detect	VBN
cord-315781-dejh8q22	99	14	several	several	JJ
cord-315781-dejh8q22	99	15	years	year	NNS
cord-315781-dejh8q22	99	16	after	after	IN
cord-315781-dejh8q22	99	17	the	the	DT
cord-315781-dejh8q22	99	18	human	human	JJ
cord-315781-dejh8q22	99	19	epidemics	epidemic	NNS
cord-315781-dejh8q22	99	20	;	;	:
cord-315781-dejh8q22	99	21	this	this	DT
cord-315781-dejh8q22	99	22	may	may	MD
cord-315781-dejh8q22	99	23	have	have	VB
cord-315781-dejh8q22	99	24	occurred	occur	VBN
cord-315781-dejh8q22	99	25	if	if	IN
cord-315781-dejh8q22	99	26	the	the	DT
cord-315781-dejh8q22	99	27	strains	strain	NNS
cord-315781-dejh8q22	99	28	were	be	VBD
cord-315781-dejh8q22	99	29	kept	keep	VBN
cord-315781-dejh8q22	99	30	unchanged	unchanged	JJ
cord-315781-dejh8q22	99	31	among	among	IN
cord-315781-dejh8q22	99	32	swine	swine	NN
cord-315781-dejh8q22	100	1	(	(	-LRB-
cord-315781-dejh8q22	100	2	Fig	Fig	NNP
cord-315781-dejh8q22	100	3	.	.	.
cord-315781-dejh8q22	100	4	3A	3A	NNP
cord-315781-dejh8q22	100	5	,	,	,
cord-315781-dejh8q22	100	6	B	B	NNP
cord-315781-dejh8q22	100	7	)	)	-RRB-
cord-315781-dejh8q22	100	8	.	.	.
cord-315781-dejh8q22	101	1	These	these	DT
cord-315781-dejh8q22	101	2	observations	observation	NNS
cord-315781-dejh8q22	101	3	suggest	suggest	VBP
cord-315781-dejh8q22	101	4	that	that	IN
cord-315781-dejh8q22	101	5	livestock	livestock	NN
cord-315781-dejh8q22	101	6	viruses	virus	NNS
cord-315781-dejh8q22	101	7	are	be	VBP
cord-315781-dejh8q22	101	8	rather	rather	RB
cord-315781-dejh8q22	101	9	conserved	conserve	VBN
cord-315781-dejh8q22	101	10	.	.	.
cord-315781-dejh8q22	102	1	Each	each	DT
cord-315781-dejh8q22	102	2	district	district	NN
cord-315781-dejh8q22	102	3	may	may	MD
cord-315781-dejh8q22	102	4	keep	keep	VB
cord-315781-dejh8q22	102	5	its	-PRON-	PRP$
cord-315781-dejh8q22	102	6	own	own	JJ
cord-315781-dejh8q22	102	7	set	set	NN
cord-315781-dejh8q22	102	8	of	of	IN
cord-315781-dejh8q22	102	9	a	a	DT
cord-315781-dejh8q22	102	10	virus	virus	NN
cord-315781-dejh8q22	102	11	library	library	NN
cord-315781-dejh8q22	102	12	and	and	CC
cord-315781-dejh8q22	102	13	we	-PRON-	PRP
cord-315781-dejh8q22	102	14	may	may	MD
cord-315781-dejh8q22	102	15	be	be	VB
cord-315781-dejh8q22	102	16	observing	observe	VBG
cord-315781-dejh8q22	102	17	only	only	RB
cord-315781-dejh8q22	102	18	a	a	DT
cord-315781-dejh8q22	102	19	limited	limited	JJ
cord-315781-dejh8q22	102	20	portion	portion	NN
cord-315781-dejh8q22	102	21	of	of	IN
cord-315781-dejh8q22	102	22	the	the	DT
cord-315781-dejh8q22	102	23	variation	variation	NN
cord-315781-dejh8q22	102	24	.	.	.
cord-315781-dejh8q22	103	1	The	the	DT
cord-315781-dejh8q22	103	2	conserved	conserved	JJ
cord-315781-dejh8q22	103	3	character	character	NN
cord-315781-dejh8q22	103	4	of	of	IN
cord-315781-dejh8q22	103	5	these	these	DT
cord-315781-dejh8q22	103	6	viruses	virus	NNS
cord-315781-dejh8q22	103	7	suggests	suggest	VBZ
cord-315781-dejh8q22	103	8	the	the	DT
cord-315781-dejh8q22	103	9	presence	presence	NN
cord-315781-dejh8q22	103	10	of	of	IN
cord-315781-dejh8q22	103	11	a	a	DT
cord-315781-dejh8q22	103	12	weaker	weak	JJR
cord-315781-dejh8q22	103	13	Scientific	scientific	JJ
cord-315781-dejh8q22	103	14	RepoRtS	reports	NN
cord-315781-dejh8q22	103	15	|	|	CD
cord-315781-dejh8q22	103	16	(	(	-LRB-
cord-315781-dejh8q22	103	17	2019	2019	CD
cord-315781-dejh8q22	103	18	)	)	-RRB-
cord-315781-dejh8q22	104	1	9:19287	9:19287	LS
cord-315781-dejh8q22	104	2	|	|	NNP
cord-315781-dejh8q22	104	3	https://doi.org/10.1038/s41598-019-55254-z	https://doi.org/10.1038/s41598-019-55254-z	NNP
cord-315781-dejh8q22	104	4	www.nature.com/scientificreports	www.nature.com/scientificreports	NNP
cord-315781-dejh8q22	104	5	www.nature.com/scientificreports/	www.nature.com/scientificreports/	NNP
cord-315781-dejh8q22	104	6	selective	selective	JJ
cord-315781-dejh8q22	104	7	pressure	pressure	NN
cord-315781-dejh8q22	104	8	for	for	IN
cord-315781-dejh8q22	104	9	newer	new	JJR
cord-315781-dejh8q22	104	10	epitopes	epitope	NNS
cord-315781-dejh8q22	104	11	.	.	.
cord-315781-dejh8q22	105	1	The	the	DT
cord-315781-dejh8q22	105	2	variety	variety	NN
cord-315781-dejh8q22	105	3	suggests	suggest	VBZ
cord-315781-dejh8q22	105	4	an	an	DT
cord-315781-dejh8q22	105	5	absence	absence	NN
cord-315781-dejh8q22	105	6	of	of	IN
cord-315781-dejh8q22	105	7	competition	competition	NN
cord-315781-dejh8q22	105	8	among	among	IN
cord-315781-dejh8q22	105	9	viruses	virus	NNS
cord-315781-dejh8q22	105	10	;	;	,
cord-315781-dejh8q22	105	11	i.e.	i.e.	FW
cord-315781-dejh8q22	105	12	,	,	,
cord-315781-dejh8q22	105	13	they	-PRON-	PRP
cord-315781-dejh8q22	105	14	might	may	MD
cord-315781-dejh8q22	105	15	have	have	VB
cord-315781-dejh8q22	105	16	a	a	DT
cord-315781-dejh8q22	105	17	limited	limited	JJ
cord-315781-dejh8q22	105	18	ability	ability	NN
cord-315781-dejh8q22	105	19	to	to	TO
cord-315781-dejh8q22	105	20	migrate	migrate	VB
cord-315781-dejh8q22	105	21	.	.	.
cord-315781-dejh8q22	106	1	There	there	EX
cord-315781-dejh8q22	106	2	were	be	VBD
cord-315781-dejh8q22	106	3	a	a	DT
cord-315781-dejh8q22	106	4	few	few	JJ
cord-315781-dejh8q22	106	5	exceptions	exception	NNS
cord-315781-dejh8q22	106	6	to	to	IN
cord-315781-dejh8q22	106	7	this	this	DT
cord-315781-dejh8q22	106	8	conservative	conservative	JJ
cord-315781-dejh8q22	106	9	endemic	endemic	JJ
cord-315781-dejh8q22	106	10	rule	rule	NN
cord-315781-dejh8q22	106	11	;	;	:
cord-315781-dejh8q22	106	12	e.g.	e.g.	RB
cord-315781-dejh8q22	106	13	,	,	,
cord-315781-dejh8q22	106	14	many	many	JJ
cord-315781-dejh8q22	106	15	types	type	NNS
cord-315781-dejh8q22	106	16	of	of	IN
cord-315781-dejh8q22	106	17	H5N1	H5N1	NNP
cord-315781-dejh8q22	106	18	chicken	chicken	NN
cord-315781-dejh8q22	106	19	viruses	virus	NNS
cord-315781-dejh8q22	106	20	were	be	VBD
cord-315781-dejh8q22	106	21	detected	detect	VBN
cord-315781-dejh8q22	106	22	in	in	IN
cord-315781-dejh8q22	106	23	East	East	NNP
cord-315781-dejh8q22	106	24	Asia	Asia	NNP
cord-315781-dejh8q22	106	25	(	(	-LRB-
cord-315781-dejh8q22	106	26	Fig	Fig	NNP
cord-315781-dejh8q22	106	27	.	.	NNP
cord-315781-dejh8q22	106	28	4	4	CD
cord-315781-dejh8q22	106	29	)	)	-RRB-
cord-315781-dejh8q22	106	30	.	.	.
cord-315781-dejh8q22	107	1	Viruses	virus	NNS
cord-315781-dejh8q22	107	2	might	may	MD
cord-315781-dejh8q22	107	3	be	be	VB
cord-315781-dejh8q22	107	4	carried	carry	VBN
cord-315781-dejh8q22	107	5	by	by	IN
cord-315781-dejh8q22	107	6	imported	import	VBN
cord-315781-dejh8q22	107	7	livestock	livestock	NN
cord-315781-dejh8q22	107	8	.	.	.
cord-315781-dejh8q22	108	1	Such	such	JJ
cord-315781-dejh8q22	108	2	migration	migration	NN
cord-315781-dejh8q22	108	3	has	have	VBZ
cord-315781-dejh8q22	108	4	also	also	RB
cord-315781-dejh8q22	108	5	been	be	VBN
cord-315781-dejh8q22	108	6	reported	report	VBN
cord-315781-dejh8q22	108	7	for	for	IN
cord-315781-dejh8q22	108	8	viruses	virus	NNS
cord-315781-dejh8q22	108	9	from	from	IN
cord-315781-dejh8q22	108	10	swine	swine	NN
cord-315781-dejh8q22	108	11	that	that	WDT
cord-315781-dejh8q22	108	12	were	be	VBD
cord-315781-dejh8q22	108	13	transported	transport	VBN
cord-315781-dejh8q22	108	14	from	from	IN
cord-315781-dejh8q22	108	15	Europe	Europe	NNP
cord-315781-dejh8q22	108	16	to	to	IN
cord-315781-dejh8q22	108	17	Mexico	Mexico	NNP
cord-315781-dejh8q22	108	18	11	11	CD
cord-315781-dejh8q22	108	19	,	,	,
cord-315781-dejh8q22	108	20	12	12	CD
cord-315781-dejh8q22	108	21	.	.	.
cord-315781-dejh8q22	109	1	The	the	DT
cord-315781-dejh8q22	109	2	group	group	NN
cord-315781-dejh8q22	109	3	U	u	VBP
cord-315781-dejh8q22	109	4	swine	swine	NN
cord-315781-dejh8q22	109	5	viruses	virus	NNS
cord-315781-dejh8q22	109	6	were	be	VBD
cord-315781-dejh8q22	109	7	further	further	RB
cord-315781-dejh8q22	109	8	separated	separate	VBN
cord-315781-dejh8q22	109	9	into	into	IN
cord-315781-dejh8q22	109	10	European	european	JJ
cord-315781-dejh8q22	109	11	and	and	CC
cord-315781-dejh8q22	109	12	Asian	asian	JJ
cord-315781-dejh8q22	109	13	subgroups	subgroup	NNS
cord-315781-dejh8q22	109	14	and	and	CC
cord-315781-dejh8q22	109	15	one	one	CD
cord-315781-dejh8q22	109	16	of	of	IN
cord-315781-dejh8q22	109	17	the	the	DT
cord-315781-dejh8q22	109	18	European	european	JJ
cord-315781-dejh8q22	109	19	viruses	virus	NNS
cord-315781-dejh8q22	109	20	was	be	VBD
cord-315781-dejh8q22	109	21	found	find	VBN
cord-315781-dejh8q22	109	22	in	in	IN
cord-315781-dejh8q22	109	23	Mexico	Mexico	NNP
cord-315781-dejh8q22	109	24	(	(	-LRB-
cord-315781-dejh8q22	109	25	Fig	Fig	NNP
cord-315781-dejh8q22	109	26	.	.	.
cord-315781-dejh8q22	110	1	S4B	S4B	NNS
cord-315781-dejh8q22	110	2	;	;	:
cord-315781-dejh8q22	110	3	U	U	NNP
cord-315781-dejh8q22	110	4	,	,	,
cord-315781-dejh8q22	110	5	PC1	PC1	NNP
cord-315781-dejh8q22	110	6	,	,	,
cord-315781-dejh8q22	110	7	indicated	indicate	VBD
cord-315781-dejh8q22	110	8	as	as	IN
cord-315781-dejh8q22	110	9	"	"	``
cord-315781-dejh8q22	110	10	2	2	CD
cord-315781-dejh8q22	110	11	"	"	''
cord-315781-dejh8q22	110	12	)	)	-RRB-
cord-315781-dejh8q22	110	13	.	.	.
cord-315781-dejh8q22	111	1	Origin	Origin	NNP
cord-315781-dejh8q22	111	2	of	of	IN
cord-315781-dejh8q22	111	3	pdm09	pdm09	NNP
cord-315781-dejh8q22	111	4	.	.	.
cord-315781-dejh8q22	112	1	The	the	DT
cord-315781-dejh8q22	112	2	pdm09	pdm09	NNP
cord-315781-dejh8q22	112	3	virus	virus	NN
cord-315781-dejh8q22	112	4	appeared	appear	VBD
cord-315781-dejh8q22	112	5	soon	soon	RB
cord-315781-dejh8q22	112	6	after	after	IN
cord-315781-dejh8q22	112	7	the	the	DT
cord-315781-dejh8q22	112	8	last	last	JJ
cord-315781-dejh8q22	112	9	outbreak	outbreak	NN
cord-315781-dejh8q22	112	10	of	of	IN
cord-315781-dejh8q22	112	11	type	type	NN
cord-315781-dejh8q22	112	12	R	r	NN
cord-315781-dejh8q22	112	13	,	,	,
cord-315781-dejh8q22	112	14	which	which	WDT
cord-315781-dejh8q22	112	15	occurred	occur	VBD
cord-315781-dejh8q22	112	16	in	in	IN
cord-315781-dejh8q22	112	17	2009	2009	CD
cord-315781-dejh8q22	112	18	,	,	,
cord-315781-dejh8q22	112	19	and	and	CC
cord-315781-dejh8q22	112	20	spread	spread	VBD
cord-315781-dejh8q22	112	21	worldwide	worldwide	RB
cord-315781-dejh8q22	112	22	within	within	IN
cord-315781-dejh8q22	112	23	1	1	CD
cord-315781-dejh8q22	112	24	year	year	NN
cord-315781-dejh8q22	113	1	(	(	-LRB-
cord-315781-dejh8q22	113	2	Fig	Fig	NNP
cord-315781-dejh8q22	113	3	.	.	.
cord-315781-dejh8q22	113	4	S5	S5	NNP
cord-315781-dejh8q22	113	5	)	)	-RRB-
cord-315781-dejh8q22	113	6	3	3	CD
cord-315781-dejh8q22	113	7	,	,	,
cord-315781-dejh8q22	113	8	8	8	CD
cord-315781-dejh8q22	113	9	,	,	,
cord-315781-dejh8q22	113	10	9	9	CD
cord-315781-dejh8q22	113	11	,	,	,
cord-315781-dejh8q22	113	12	11	11	CD
cord-315781-dejh8q22	113	13	.	.	.
cord-315781-dejh8q22	114	1	The	the	DT
cord-315781-dejh8q22	114	2	origin	origin	NN
cord-315781-dejh8q22	114	3	of	of	IN
cord-315781-dejh8q22	114	4	pdm09	pdm09	NNP
cord-315781-dejh8q22	114	5	is	be	VBZ
cord-315781-dejh8q22	114	6	thought	think	VBN
cord-315781-dejh8q22	114	7	to	to	TO
cord-315781-dejh8q22	114	8	be	be	VB
cord-315781-dejh8q22	114	9	swine	swine	NN
cord-315781-dejh8q22	114	10	viruses	virus	NNS
cord-315781-dejh8q22	114	11	from	from	IN
cord-315781-dejh8q22	114	12	Mexico	Mexico	NNP
cord-315781-dejh8q22	114	13	8	8	CD
cord-315781-dejh8q22	114	14	,	,	,
cord-315781-dejh8q22	114	15	9	9	CD
cord-315781-dejh8q22	114	16	,	,	,
cord-315781-dejh8q22	114	17	11	11	CD
cord-315781-dejh8q22	114	18	;	;	:
cord-315781-dejh8q22	114	19	however	however	RB
cord-315781-dejh8q22	114	20	,	,	,
cord-315781-dejh8q22	114	21	swine	swine	NN
cord-315781-dejh8q22	114	22	strains	strain	NNS
cord-315781-dejh8q22	114	23	were	be	VBD
cord-315781-dejh8q22	114	24	not	not	RB
cord-315781-dejh8q22	114	25	recorded	record	VBN
cord-315781-dejh8q22	114	26	before	before	IN
cord-315781-dejh8q22	114	27	the	the	DT
cord-315781-dejh8q22	114	28	pandemic	pandemic	NN
cord-315781-dejh8q22	114	29	in	in	IN
cord-315781-dejh8q22	114	30	that	that	DT
cord-315781-dejh8q22	114	31	country	country	NN
cord-315781-dejh8q22	114	32	.	.	.
cord-315781-dejh8q22	115	1	A	a	DT
cord-315781-dejh8q22	115	2	later	later	JJ
cord-315781-dejh8q22	115	3	study	study	NN
cord-315781-dejh8q22	115	4	disclosed	disclose	VBD
cord-315781-dejh8q22	115	5	that	that	IN
cord-315781-dejh8q22	115	6	several	several	JJ
cord-315781-dejh8q22	115	7	viral	viral	JJ
cord-315781-dejh8q22	115	8	types	type	NNS
cord-315781-dejh8q22	115	9	existed	exist	VBD
cord-315781-dejh8q22	115	10	11	11	CD
cord-315781-dejh8q22	115	11	,	,	,
cord-315781-dejh8q22	115	12	which	which	WDT
cord-315781-dejh8q22	115	13	included	include	VBD
cord-315781-dejh8q22	115	14	groups	group	NNS
cord-315781-dejh8q22	115	15	that	that	WDT
cord-315781-dejh8q22	115	16	were	be	VBD
cord-315781-dejh8q22	115	17	mainly	mainly	RB
cord-315781-dejh8q22	115	18	found	find	VBN
cord-315781-dejh8q22	115	19	in	in	IN
cord-315781-dejh8q22	115	20	Asia	Asia	NNP
cord-315781-dejh8q22	115	21	or	or	CC
cord-315781-dejh8q22	115	22	Europe	Europe	NNP
cord-315781-dejh8q22	115	23	(	(	-LRB-
cord-315781-dejh8q22	115	24	Fig	Fig	NNP
cord-315781-dejh8q22	115	25	.	.	.
cord-315781-dejh8q22	115	26	S4B	S4B	NNP
cord-315781-dejh8q22	115	27	)	)	-RRB-
cord-315781-dejh8q22	115	28	,	,	,
cord-315781-dejh8q22	115	29	as	as	RB
cord-315781-dejh8q22	115	30	well	well	RB
cord-315781-dejh8q22	115	31	as	as	IN
cord-315781-dejh8q22	115	32	human	human	JJ
cord-315781-dejh8q22	115	33	M	M	NNP
cord-315781-dejh8q22	115	34	and	and	CC
cord-315781-dejh8q22	115	35	R	r	NN
cord-315781-dejh8q22	115	36	viruses	virus	NNS
cord-315781-dejh8q22	115	37	(	(	-LRB-
cord-315781-dejh8q22	115	38	Fig	Fig	NNP
cord-315781-dejh8q22	115	39	.	.	.
cord-315781-dejh8q22	115	40	3A	3A	NNP
cord-315781-dejh8q22	115	41	,	,	,
cord-315781-dejh8q22	115	42	B	B	NNP
cord-315781-dejh8q22	115	43	)	)	-RRB-
cord-315781-dejh8q22	115	44	.	.	.
cord-315781-dejh8q22	116	1	Although	although	IN
cord-315781-dejh8q22	116	2	group	group	NN
cord-315781-dejh8q22	116	3	M	M	NNP
cord-315781-dejh8q22	116	4	viruses	virus	NNS
cord-315781-dejh8q22	116	5	were	be	VBD
cord-315781-dejh8q22	116	6	reported	report	VBN
cord-315781-dejh8q22	116	7	sporadically	sporadically	RB
cord-315781-dejh8q22	116	8	in	in	IN
cord-315781-dejh8q22	116	9	humans	human	NNS
cord-315781-dejh8q22	116	10	before	before	IN
cord-315781-dejh8q22	116	11	2009	2009	CD
cord-315781-dejh8q22	116	12	,	,	,
cord-315781-dejh8q22	116	13	the	the	DT
cord-315781-dejh8q22	116	14	human	human	JJ
cord-315781-dejh8q22	116	15	pdm09	pdm09	CD
cord-315781-dejh8q22	116	16	virus	virus	NN
cord-315781-dejh8q22	116	17	was	be	VBD
cord-315781-dejh8q22	116	18	characteristic	characteristic	JJ
cord-315781-dejh8q22	116	19	as	as	IN
cord-315781-dejh8q22	116	20	a	a	DT
cord-315781-dejh8q22	116	21	small	small	JJ
cord-315781-dejh8q22	116	22	cluster	cluster	NN
cord-315781-dejh8q22	116	23	in	in	IN
cord-315781-dejh8q22	116	24	the	the	DT
cord-315781-dejh8q22	116	25	plot	plot	NN
cord-315781-dejh8q22	116	26	(	(	-LRB-
cord-315781-dejh8q22	116	27	Fig	Fig	NNP
cord-315781-dejh8q22	116	28	.	.	.
cord-315781-dejh8q22	116	29	1C	1C	NNP
cord-315781-dejh8q22	116	30	)	)	-RRB-
cord-315781-dejh8q22	116	31	.	.	.
cord-315781-dejh8q22	117	1	Such	such	JJ
cord-315781-dejh8q22	117	2	characteristics	characteristic	NNS
cord-315781-dejh8q22	117	3	were	be	VBD
cord-315781-dejh8q22	117	4	also	also	RB
cord-315781-dejh8q22	117	5	observed	observe	VBN
cord-315781-dejh8q22	117	6	in	in	IN
cord-315781-dejh8q22	117	7	the	the	DT
cord-315781-dejh8q22	117	8	other	other	JJ
cord-315781-dejh8q22	117	9	segments	segment	NNS
cord-315781-dejh8q22	117	10	(	(	-LRB-
cord-315781-dejh8q22	117	11	Fig	Fig	NNP
cord-315781-dejh8q22	117	12	.	.	.
cord-315781-dejh8q22	117	13	S2	S2	NNP
cord-315781-dejh8q22	117	14	)	)	-RRB-
cord-315781-dejh8q22	117	15	.	.	.
cord-315781-dejh8q22	117	16	 	 	_SP
cord-315781-dejh8q22	118	1	The	the	DT
cord-315781-dejh8q22	118	2	analysis	analysis	NN
cord-315781-dejh8q22	118	3	of	of	IN
cord-315781-dejh8q22	118	4	data	datum	NNS
cord-315781-dejh8q22	118	5	for	for	IN
cord-315781-dejh8q22	118	6	scientific	scientific	JJ
cord-315781-dejh8q22	118	7	purposes	purpose	NNS
cord-315781-dejh8q22	118	8	requires	require	VBZ
cord-315781-dejh8q22	118	9	objectivity	objectivity	NN
cord-315781-dejh8q22	118	10	.	.	.
cord-315781-dejh8q22	119	1	This	this	DT
cord-315781-dejh8q22	119	2	can	can	MD
cord-315781-dejh8q22	119	3	not	not	RB
cord-315781-dejh8q22	119	4	be	be	VB
cord-315781-dejh8q22	119	5	achieved	achieve	VBN
cord-315781-dejh8q22	119	6	without	without	IN
cord-315781-dejh8q22	119	7	considering	consider	VBG
cord-315781-dejh8q22	119	8	the	the	DT
cord-315781-dejh8q22	119	9	falsifiability	falsifiability	NN
cord-315781-dejh8q22	119	10	of	of	IN
cord-315781-dejh8q22	119	11	models	model	NNS
cord-315781-dejh8q22	119	12	14	14	CD
cord-315781-dejh8q22	119	13	,	,	,
cord-315781-dejh8q22	119	14	15	15	CD
cord-315781-dejh8q22	119	15	.	.	.
cord-315781-dejh8q22	120	1	Here	here	RB
cord-315781-dejh8q22	120	2	,	,	,
cord-315781-dejh8q22	120	3	we	-PRON-	PRP
cord-315781-dejh8q22	120	4	presented	present	VBD
cord-315781-dejh8q22	120	5	views	view	NNS
cord-315781-dejh8q22	120	6	that	that	WDT
cord-315781-dejh8q22	120	7	are	be	VBP
cord-315781-dejh8q22	120	8	very	very	RB
cord-315781-dejh8q22	120	9	different	different	JJ
cord-315781-dejh8q22	120	10	from	from	IN
cord-315781-dejh8q22	120	11	those	those	DT
cord-315781-dejh8q22	120	12	of	of	IN
cord-315781-dejh8q22	120	13	previous	previous	JJ
cord-315781-dejh8q22	120	14	studies	study	NNS
cord-315781-dejh8q22	120	15	.	.	.
cord-315781-dejh8q22	121	1	The	the	DT
cord-315781-dejh8q22	121	2	discrepancies	discrepancy	NNS
cord-315781-dejh8q22	121	3	were	be	VBD
cord-315781-dejh8q22	121	4	generated	generate	VBN
cord-315781-dejh8q22	121	5	by	by	IN
cord-315781-dejh8q22	121	6	differences	difference	NNS
cord-315781-dejh8q22	121	7	in	in	IN
cord-315781-dejh8q22	121	8	the	the	DT
cord-315781-dejh8q22	121	9	methodologies	methodology	NNS
cord-315781-dejh8q22	121	10	,	,	,
cord-315781-dejh8q22	121	11	because	because	IN
cord-315781-dejh8q22	121	12	many	many	JJ
cord-315781-dejh8q22	121	13	of	of	IN
cord-315781-dejh8q22	121	14	the	the	DT
cord-315781-dejh8q22	121	15	data	datum	NNS
cord-315781-dejh8q22	121	16	analysed	analyse	VBN
cord-315781-dejh8q22	121	17	were	be	VBD
cord-315781-dejh8q22	121	18	common	common	JJ
cord-315781-dejh8q22	121	19	among	among	IN
cord-315781-dejh8q22	121	20	studies	study	NNS
cord-315781-dejh8q22	121	21	.	.	.
cord-315781-dejh8q22	122	1	Here	here	RB
cord-315781-dejh8q22	122	2	,	,	,
cord-315781-dejh8q22	122	3	we	-PRON-	PRP
cord-315781-dejh8q22	122	4	wish	wish	VBP
cord-315781-dejh8q22	122	5	to	to	TO
cord-315781-dejh8q22	122	6	show	show	VB
cord-315781-dejh8q22	122	7	that	that	IN
cord-315781-dejh8q22	122	8	our	-PRON-	PRP$
cord-315781-dejh8q22	122	9	study	study	NN
cord-315781-dejh8q22	122	10	has	have	VBZ
cord-315781-dejh8q22	122	11	better	well	JJR
cord-315781-dejh8q22	122	12	falsifiability	falsifiability	NN
cord-315781-dejh8q22	122	13	6	6	CD
cord-315781-dejh8q22	122	14	.	.	.
cord-315781-dejh8q22	123	1	A	a	DT
cord-315781-dejh8q22	123	2	sequence	sequence	NN
cord-315781-dejh8q22	123	3	matrix	matrix	NN
cord-315781-dejh8q22	123	4	is	be	VBZ
cord-315781-dejh8q22	123	5	essentially	essentially	RB
cord-315781-dejh8q22	123	6	composed	compose	VBN
cord-315781-dejh8q22	123	7	of	of	IN
cord-315781-dejh8q22	123	8	multivariate	multivariate	JJ
cord-315781-dejh8q22	123	9	data	datum	NNS
cord-315781-dejh8q22	123	10	with	with	IN
cord-315781-dejh8q22	123	11	a	a	DT
cord-315781-dejh8q22	123	12	large	large	JJ
cord-315781-dejh8q22	123	13	number	number	NN
cord-315781-dejh8q22	123	14	of	of	IN
cord-315781-dejh8q22	123	15	dimensions	dimension	NNS
cord-315781-dejh8q22	123	16	6	6	CD
cord-315781-dejh8q22	123	17	.	.	.
cord-315781-dejh8q22	124	1	Previous	previous	JJ
cord-315781-dejh8q22	124	2	studies	study	NNS
cord-315781-dejh8q22	124	3	used	use	VBD
cord-315781-dejh8q22	124	4	tree	tree	NN
cord-315781-dejh8q22	124	5	-	-	HYPH
cord-315781-dejh8q22	124	6	based	base	VBN
cord-315781-dejh8q22	124	7	models	model	NNS
cord-315781-dejh8q22	124	8	(	(	-LRB-
cord-315781-dejh8q22	124	9	Fig	Fig	NNP
cord-315781-dejh8q22	124	10	.	.	.
cord-315781-dejh8q22	124	11	1	1	CD
cord-315781-dejh8q22	124	12	)	)	-RRB-
cord-315781-dejh8q22	124	13	which	which	WDT
cord-315781-dejh8q22	124	14	can	can	MD
cord-315781-dejh8q22	124	15	handle	handle	VB
cord-315781-dejh8q22	124	16	only	only	RB
cord-315781-dejh8q22	124	17	a	a	DT
cord-315781-dejh8q22	124	18	single	single	JJ
cord-315781-dejh8q22	124	19	dimension	dimension	NN
cord-315781-dejh8q22	124	20	7	7	CD
cord-315781-dejh8q22	124	21	;	;	,
cord-315781-dejh8q22	124	22	such	such	JJ
cord-315781-dejh8q22	124	23	tree	tree	NN
cord-315781-dejh8q22	124	24	models	model	NNS
cord-315781-dejh8q22	124	25	have	have	VBP
cord-315781-dejh8q22	124	26	to	to	TO
cord-315781-dejh8q22	124	27	ignore	ignore	VB
cord-315781-dejh8q22	124	28	the	the	DT
cord-315781-dejh8q22	124	29	real	real	JJ
cord-315781-dejh8q22	124	30	data	data	NN
cord-315781-dejh8q22	124	31	structure	structure	NN
cord-315781-dejh8q22	124	32	.	.	.
cord-315781-dejh8q22	125	1	The	the	DT
cord-315781-dejh8q22	125	2	understanding	understanding	NN
cord-315781-dejh8q22	125	3	of	of	IN
cord-315781-dejh8q22	125	4	clusters	cluster	NNS
cord-315781-dejh8q22	125	5	requires	require	VBZ
cord-315781-dejh8q22	125	6	advanced	advanced	JJ
cord-315781-dejh8q22	125	7	judgement	judgement	NN
cord-315781-dejh8q22	125	8	calls	call	NNS
cord-315781-dejh8q22	125	9	;	;	:
cord-315781-dejh8q22	125	10	hence	hence	RB
cord-315781-dejh8q22	125	11	,	,	,
cord-315781-dejh8q22	125	12	it	-PRON-	PRP
cord-315781-dejh8q22	125	13	may	may	MD
cord-315781-dejh8q22	125	14	fail	fail	VB
cord-315781-dejh8q22	125	15	easily	easily	RB
cord-315781-dejh8q22	125	16	and	and	CC
cord-315781-dejh8q22	125	17	the	the	DT
cord-315781-dejh8q22	125	18	comparison	comparison	NN
cord-315781-dejh8q22	125	19	of	of	IN
cord-315781-dejh8q22	125	20	the	the	DT
cord-315781-dejh8q22	125	21	results	result	NNS
cord-315781-dejh8q22	125	22	of	of	IN
cord-315781-dejh8q22	125	23	different	different	JJ
cord-315781-dejh8q22	125	24	segments	segment	NNS
cord-315781-dejh8q22	125	25	or	or	CC
cord-315781-dejh8q22	125	26	types	type	NNS
cord-315781-dejh8q22	125	27	is	be	VBZ
cord-315781-dejh8q22	125	28	difficult	difficult	JJ
cord-315781-dejh8q22	125	29	.	.	.
cord-315781-dejh8q22	126	1	In	in	IN
cord-315781-dejh8q22	126	2	contrast	contrast	NN
cord-315781-dejh8q22	126	3	,	,	,
cord-315781-dejh8q22	126	4	PCA	PCA	NNP
cord-315781-dejh8q22	126	5	does	do	VBZ
cord-315781-dejh8q22	126	6	not	not	RB
cord-315781-dejh8q22	126	7	have	have	VB
cord-315781-dejh8q22	126	8	limitations	limitation	NNS
cord-315781-dejh8q22	126	9	regarding	regard	VBG
cord-315781-dejh8q22	126	10	the	the	DT
cord-315781-dejh8q22	126	11	shape	shape	NN
cord-315781-dejh8q22	126	12	of	of	IN
cord-315781-dejh8q22	126	13	presentations	presentation	NNS
cord-315781-dejh8q22	126	14	or	or	CC
cord-315781-dejh8q22	126	15	the	the	DT
cord-315781-dejh8q22	126	16	number	number	NN
cord-315781-dejh8q22	126	17	of	of	IN
cord-315781-dejh8q22	126	18	dimensions	dimension	NNS
cord-315781-dejh8q22	126	19	;	;	:
cord-315781-dejh8q22	126	20	thus	thus	RB
cord-315781-dejh8q22	126	21	,	,	,
cord-315781-dejh8q22	126	22	it	-PRON-	PRP
cord-315781-dejh8q22	126	23	has	have	VBZ
cord-315781-dejh8q22	126	24	better	well	JJR
cord-315781-dejh8q22	126	25	objectivity	objectivity	NN
cord-315781-dejh8q22	126	26	6	6	CD
cord-315781-dejh8q22	126	27	.	.	.
cord-315781-dejh8q22	127	1	For	for	IN
cord-315781-dejh8q22	127	2	instance	instance	NN
cord-315781-dejh8q22	127	3	,	,	,
cord-315781-dejh8q22	127	4	the	the	DT
cord-315781-dejh8q22	127	5	attributions	attribution	NNS
cord-315781-dejh8q22	127	6	of	of	IN
cord-315781-dejh8q22	127	7	clusters	cluster	NNS
cord-315781-dejh8q22	127	8	presented	present	VBN
cord-315781-dejh8q22	127	9	in	in	IN
cord-315781-dejh8q22	127	10	Figs	Figs	NNP
cord-315781-dejh8q22	127	11	.	.	.
cord-315781-dejh8q22	128	1	1C	1C	NNP
cord-315781-dejh8q22	128	2	and	and	CC
cord-315781-dejh8q22	128	3	S2	S2	NNP
cord-315781-dejh8q22	128	4	should	should	MD
cord-315781-dejh8q22	128	5	not	not	RB
cord-315781-dejh8q22	128	6	cause	cause	VB
cord-315781-dejh8q22	128	7	confusion	confusion	NN
cord-315781-dejh8q22	128	8	.	.	.
cord-315781-dejh8q22	129	1	Moreover	moreover	RB
cord-315781-dejh8q22	129	2	,	,	,
cord-315781-dejh8q22	129	3	the	the	DT
cord-315781-dejh8q22	129	4	assumption	assumption	NN
cord-315781-dejh8q22	129	5	that	that	IN
cord-315781-dejh8q22	129	6	"	"	``
cord-315781-dejh8q22	129	7	the	the	DT
cord-315781-dejh8q22	129	8	relationship	relationship	NN
cord-315781-dejh8q22	129	9	among	among	IN
cord-315781-dejh8q22	129	10	samples	sample	NNS
cord-315781-dejh8q22	129	11	should	should	MD
cord-315781-dejh8q22	129	12	be	be	VB
cord-315781-dejh8q22	129	13	a	a	DT
cord-315781-dejh8q22	129	14	tree	tree	NN
cord-315781-dejh8q22	129	15	-	-	HYPH
cord-315781-dejh8q22	129	16	like	like	JJ
cord-315781-dejh8q22	129	17	structure	structure	NN
cord-315781-dejh8q22	129	18	"	"	''
cord-315781-dejh8q22	129	19	can	can	MD
cord-315781-dejh8q22	129	20	not	not	RB
cord-315781-dejh8q22	129	21	be	be	VB
cord-315781-dejh8q22	129	22	verified	verify	VBN
cord-315781-dejh8q22	129	23	.	.	.
cord-315781-dejh8q22	130	1	Our	-PRON-	PRP$
cord-315781-dejh8q22	130	2	analyses	analysis	NNS
cord-315781-dejh8q22	130	3	are	be	VBP
cord-315781-dejh8q22	130	4	free	free	JJ
cord-315781-dejh8q22	130	5	from	from	IN
cord-315781-dejh8q22	130	6	such	such	JJ
cord-315781-dejh8q22	130	7	assumptions	assumption	NNS
cord-315781-dejh8q22	130	8	.	.	.
cord-315781-dejh8q22	131	1	www.nature.com/scientificreports	www.nature.com/scientificreport	NNS
cord-315781-dejh8q22	132	1	www.nature.com/scientificreports/	www.nature.com/scientificreports/	NNP
cord-315781-dejh8q22	133	1	One	one	CD
cord-315781-dejh8q22	133	2	of	of	IN
cord-315781-dejh8q22	133	3	the	the	DT
cord-315781-dejh8q22	133	4	major	major	JJ
cord-315781-dejh8q22	133	5	differences	difference	NNS
cord-315781-dejh8q22	133	6	observed	observe	VBD
cord-315781-dejh8q22	133	7	was	be	VBD
cord-315781-dejh8q22	133	8	the	the	DT
cord-315781-dejh8q22	133	9	direct	direct	JJ
cord-315781-dejh8q22	133	10	shift	shift	NN
cord-315781-dejh8q22	133	11	from	from	IN
cord-315781-dejh8q22	133	12	avian	avian	JJ
cord-315781-dejh8q22	133	13	to	to	IN
cord-315781-dejh8q22	133	14	swine	swine	NN
cord-315781-dejh8q22	133	15	or	or	CC
cord-315781-dejh8q22	133	16	human	human	JJ
cord-315781-dejh8q22	133	17	viruses	virus	NNS
cord-315781-dejh8q22	133	18	.	.	.
cord-315781-dejh8q22	134	1	Although	although	IN
cord-315781-dejh8q22	134	2	these	these	DT
cord-315781-dejh8q22	134	3	shifts	shift	NNS
cord-315781-dejh8q22	134	4	were	be	VBD
cord-315781-dejh8q22	134	5	thought	think	VBN
cord-315781-dejh8q22	134	6	to	to	TO
cord-315781-dejh8q22	134	7	explain	explain	VB
cord-315781-dejh8q22	134	8	the	the	DT
cord-315781-dejh8q22	134	9	1918	1918	CD
cord-315781-dejh8q22	134	10	5,13,16	5,13,16	CD
cord-315781-dejh8q22	134	11	and	and	CC
cord-315781-dejh8q22	134	12	2009	2009	CD
cord-315781-dejh8q22	134	13	8	8	CD
cord-315781-dejh8q22	134	14	,	,	,
cord-315781-dejh8q22	134	15	9	9	CD
cord-315781-dejh8q22	134	16	,	,	,
cord-315781-dejh8q22	134	17	11	11	CD
cord-315781-dejh8q22	134	18	pandemic	pandemic	NN
cord-315781-dejh8q22	134	19	viruses	virus	NNS
cord-315781-dejh8q22	134	20	,	,	,
cord-315781-dejh8q22	134	21	the	the	DT
cord-315781-dejh8q22	134	22	segments	segment	NNS
cord-315781-dejh8q22	134	23	of	of	IN
cord-315781-dejh8q22	134	24	avian	avian	JJ
cord-315781-dejh8q22	134	25	viruses	virus	NNS
cord-315781-dejh8q22	134	26	were	be	VBD
cord-315781-dejh8q22	134	27	separated	separate	VBN
cord-315781-dejh8q22	134	28	from	from	IN
cord-315781-dejh8q22	134	29	any	any	DT
cord-315781-dejh8q22	134	30	swine	swine	NN
cord-315781-dejh8q22	134	31	or	or	CC
cord-315781-dejh8q22	134	32	human	human	JJ
cord-315781-dejh8q22	134	33	segments	segment	NNS
cord-315781-dejh8q22	134	34	,	,	,
cord-315781-dejh8q22	134	35	even	even	RB
cord-315781-dejh8q22	134	36	those	those	DT
cord-315781-dejh8q22	134	37	that	that	WDT
cord-315781-dejh8q22	134	38	were	be	VBD
cord-315781-dejh8q22	134	39	thought	think	VBN
cord-315781-dejh8q22	134	40	to	to	TO
cord-315781-dejh8q22	134	41	be	be	VB
cord-315781-dejh8q22	134	42	close	close	JJ
cord-315781-dejh8q22	134	43	to	to	IN
cord-315781-dejh8q22	134	44	the	the	DT
cord-315781-dejh8q22	134	45	source	source	NN
cord-315781-dejh8q22	134	46	(	(	-LRB-
cord-315781-dejh8q22	134	47	Fig	Fig	NNP
cord-315781-dejh8q22	134	48	.	.	.
cord-315781-dejh8q22	134	49	S2	S2	NNP
cord-315781-dejh8q22	134	50	,	,	,
cord-315781-dejh8q22	134	51	A	A	NNP
cord-315781-dejh8q22	134	52	,	,	,
cord-315781-dejh8q22	134	53	orange	orange	NN
cord-315781-dejh8q22	134	54	)	)	-RRB-
cord-315781-dejh8q22	134	55	17	17	CD
cord-315781-dejh8q22	134	56	.	.	.
cord-315781-dejh8q22	135	1	Therefore	therefore	RB
cord-315781-dejh8q22	135	2	,	,	,
cord-315781-dejh8q22	135	3	it	-PRON-	PRP
cord-315781-dejh8q22	135	4	is	be	VBZ
cord-315781-dejh8q22	135	5	difficult	difficult	JJ
cord-315781-dejh8q22	135	6	to	to	TO
cord-315781-dejh8q22	135	7	estimate	estimate	VB
cord-315781-dejh8q22	135	8	such	such	JJ
cord-315781-dejh8q22	135	9	direct	direct	JJ
cord-315781-dejh8q22	135	10	shifts	shift	NNS
cord-315781-dejh8q22	135	11	.	.	.
cord-315781-dejh8q22	136	1	In	in	IN
cord-315781-dejh8q22	136	2	fact	fact	NN
cord-315781-dejh8q22	136	3	,	,	,
cord-315781-dejh8q22	136	4	the	the	DT
cord-315781-dejh8q22	136	5	cluster	cluster	NN
cord-315781-dejh8q22	136	6	called	call	VBN
cord-315781-dejh8q22	136	7	"	"	``
cord-315781-dejh8q22	136	8	triple	triple	JJ
cord-315781-dejh8q22	136	9	reassortant	reassortant	NN
cord-315781-dejh8q22	136	10	"	"	''
cord-315781-dejh8q22	136	11	disappeared	disappear	VBD
cord-315781-dejh8q22	136	12	(	(	-LRB-
cord-315781-dejh8q22	136	13	Fig	Fig	NNP
cord-315781-dejh8q22	136	14	.	.	.
cord-315781-dejh8q22	136	15	2S	2s	CD
cord-315781-dejh8q22	136	16	)	)	-RRB-
cord-315781-dejh8q22	136	17	;	;	:
cord-315781-dejh8q22	136	18	this	this	DT
cord-315781-dejh8q22	136	19	class	class	NN
cord-315781-dejh8q22	136	20	was	be	VBD
cord-315781-dejh8q22	136	21	detected	detect	VBN
cord-315781-dejh8q22	136	22	as	as	IN
cord-315781-dejh8q22	136	23	a	a	DT
cord-315781-dejh8q22	136	24	pandemic	pandemic	NN
cord-315781-dejh8q22	136	25	swine	swine	NN
cord-315781-dejh8q22	136	26	H3N2	H3N2	NNP
cord-315781-dejh8q22	136	27	virus	virus	NN
cord-315781-dejh8q22	136	28	17	17	CD
cord-315781-dejh8q22	136	29	and	and	CC
cord-315781-dejh8q22	136	30	also	also	RB
cord-315781-dejh8q22	136	31	presented	present	VBD
cord-315781-dejh8q22	136	32	some	some	DT
cord-315781-dejh8q22	136	33	clusters	cluster	NNS
cord-315781-dejh8q22	136	34	of	of	IN
cord-315781-dejh8q22	136	35	H1N1	H1N1	NNP
cord-315781-dejh8q22	136	36	8	8	CD
cord-315781-dejh8q22	136	37	,	,	,
cord-315781-dejh8q22	136	38	9	9	CD
cord-315781-dejh8q22	136	39	,	,	,
cord-315781-dejh8q22	136	40	11	11	CD
cord-315781-dejh8q22	136	41	.	.	.
cord-315781-dejh8q22	137	1	Although	although	IN
cord-315781-dejh8q22	137	2	avian	avian	JJ
cord-315781-dejh8q22	137	3	viruses	virus	NNS
cord-315781-dejh8q22	137	4	might	may	MD
cord-315781-dejh8q22	137	5	be	be	VB
cord-315781-dejh8q22	137	6	the	the	DT
cord-315781-dejh8q22	137	7	origin	origin	NN
cord-315781-dejh8q22	137	8	of	of	IN
cord-315781-dejh8q22	137	9	the	the	DT
cord-315781-dejh8q22	137	10	H1	H1	NNP
cord-315781-dejh8q22	137	11	viruses	virus	NNS
cord-315781-dejh8q22	137	12	,	,	,
cord-315781-dejh8q22	137	13	they	-PRON-	PRP
cord-315781-dejh8q22	137	14	might	may	MD
cord-315781-dejh8q22	137	15	have	have	VB
cord-315781-dejh8q22	137	16	a	a	DT
cord-315781-dejh8q22	137	17	limited	limited	JJ
cord-315781-dejh8q22	137	18	capacity	capacity	NN
cord-315781-dejh8q22	137	19	to	to	TO
cord-315781-dejh8q22	137	20	infect	infect	VB
cord-315781-dejh8q22	137	21	swine	swine	NNS
cord-315781-dejh8q22	137	22	or	or	CC
cord-315781-dejh8q22	137	23	humans	human	NNS
cord-315781-dejh8q22	137	24	,	,	,
cord-315781-dejh8q22	137	25	and	and	CC
cord-315781-dejh8q22	137	26	vice	vice	NN
cord-315781-dejh8q22	137	27	versa	versa	RB
cord-315781-dejh8q22	137	28	.	.	.
cord-315781-dejh8q22	138	1	Among	among	IN
cord-315781-dejh8q22	138	2	the	the	DT
cord-315781-dejh8q22	138	3	samples	sample	NNS
cord-315781-dejh8q22	138	4	studied	study	VBN
cord-315781-dejh8q22	138	5	here	here	RB
cord-315781-dejh8q22	138	6	,	,	,
cord-315781-dejh8q22	138	7	there	there	EX
cord-315781-dejh8q22	138	8	was	be	VBD
cord-315781-dejh8q22	138	9	only	only	RB
cord-315781-dejh8q22	138	10	one	one	CD
cord-315781-dejh8q22	138	11	example	example	NN
cord-315781-dejh8q22	138	12	of	of	IN
cord-315781-dejh8q22	138	13	such	such	JJ
cord-315781-dejh8q22	138	14	transmittance	transmittance	NN
cord-315781-dejh8q22	138	15	,	,	,
cord-315781-dejh8q22	138	16	which	which	WDT
cord-315781-dejh8q22	138	17	may	may	MD
cord-315781-dejh8q22	138	18	have	have	VB
cord-315781-dejh8q22	138	19	occurred	occur	VBN
cord-315781-dejh8q22	138	20	from	from	IN
cord-315781-dejh8q22	138	21	humans	human	NNS
cord-315781-dejh8q22	138	22	to	to	IN
cord-315781-dejh8q22	138	23	turkeys	turkey	NNS
cord-315781-dejh8q22	138	24	(	(	-LRB-
cord-315781-dejh8q22	138	25	NCBI	NCBI	NNP
cord-315781-dejh8q22	138	26	taxonomy	taxonomy	NN
cord-315781-dejh8q22	138	27	ID	ID	NNP
cord-315781-dejh8q22	138	28	:	:	:
cord-315781-dejh8q22	138	29	1848980	1848980	CD
cord-315781-dejh8q22	138	30	)	)	-RRB-
cord-315781-dejh8q22	138	31	in	in	IN
cord-315781-dejh8q22	138	32	contrast	contrast	NN
cord-315781-dejh8q22	138	33	to	to	IN
cord-315781-dejh8q22	138	34	the	the	DT
cord-315781-dejh8q22	138	35	occasional	occasional	JJ
cord-315781-dejh8q22	138	36	transmittance	transmittance	NN
cord-315781-dejh8q22	138	37	observed	observe	VBN
cord-315781-dejh8q22	138	38	between	between	IN
cord-315781-dejh8q22	138	39	humans	human	NNS
cord-315781-dejh8q22	138	40	and	and	CC
cord-315781-dejh8q22	138	41	swine	swine	NN
cord-315781-dejh8q22	138	42	(	(	-LRB-
cord-315781-dejh8q22	138	43	Figs	fig	NNS
cord-315781-dejh8q22	138	44	.	.	.
cord-315781-dejh8q22	139	1	1C	1C	NNP
cord-315781-dejh8q22	139	2	and	and	CC
cord-315781-dejh8q22	139	3	4A	4a	CD
cord-315781-dejh8q22	139	4	,	,	,
cord-315781-dejh8q22	139	5	B	b	NN
cord-315781-dejh8q22	139	6	)	)	-RRB-
cord-315781-dejh8q22	139	7	.	.	.
cord-315781-dejh8q22	140	1	The	the	DT
cord-315781-dejh8q22	140	2	three	three	CD
cord-315781-dejh8q22	140	3	groups	group	NNS
cord-315781-dejh8q22	140	4	,	,	,
cord-315781-dejh8q22	140	5	R	R	NNP
cord-315781-dejh8q22	140	6	,	,	,
cord-315781-dejh8q22	140	7	M	M	NNP
cord-315781-dejh8q22	140	8	,	,	,
cord-315781-dejh8q22	140	9	and	and	CC
cord-315781-dejh8q22	140	10	U	U	NNP
cord-315781-dejh8q22	140	11	,	,	,
cord-315781-dejh8q22	140	12	may	may	MD
cord-315781-dejh8q22	140	13	have	have	VB
cord-315781-dejh8q22	140	14	branched	branch	VBN
cord-315781-dejh8q22	140	15	out	out	RP
cord-315781-dejh8q22	140	16	from	from	IN
cord-315781-dejh8q22	140	17	the	the	DT
cord-315781-dejh8q22	140	18	origin	origin	NN
cord-315781-dejh8q22	140	19	to	to	TO
cord-315781-dejh8q22	140	20	achieve	achieve	VB
cord-315781-dejh8q22	140	21	better	well	JJR
cord-315781-dejh8q22	140	22	infectivity	infectivity	NN
cord-315781-dejh8q22	140	23	in	in	IN
cord-315781-dejh8q22	140	24	swine	swine	NN
cord-315781-dejh8q22	140	25	or	or	CC
cord-315781-dejh8q22	140	26	humans	human	NNS
cord-315781-dejh8q22	141	1	(	(	-LRB-
cord-315781-dejh8q22	141	2	Fig	Fig	NNP
cord-315781-dejh8q22	141	3	.	.	NNP
cord-315781-dejh8q22	141	4	5	5	CD
cord-315781-dejh8q22	141	5	)	)	-RRB-
cord-315781-dejh8q22	141	6	.	.	.
cord-315781-dejh8q22	142	1	The	the	DT
cord-315781-dejh8q22	142	2	1943	1943	CD
cord-315781-dejh8q22	142	3	human	human	NN
cord-315781-dejh8q22	142	4	strain	strain	NN
cord-315781-dejh8q22	142	5	may	may	MD
cord-315781-dejh8q22	142	6	represent	represent	VB
cord-315781-dejh8q22	142	7	an	an	DT
cord-315781-dejh8q22	142	8	earlier	early	JJR
cord-315781-dejh8q22	142	9	process	process	NN
cord-315781-dejh8q22	142	10	of	of	IN
cord-315781-dejh8q22	142	11	branching	branch	VBG
cord-315781-dejh8q22	142	12	out	out	RP
cord-315781-dejh8q22	143	1	(	(	-LRB-
cord-315781-dejh8q22	143	2	Fig	Fig	NNP
cord-315781-dejh8q22	143	3	.	.	.
cord-315781-dejh8q22	143	4	S2	S2	NNP
cord-315781-dejh8q22	143	5	)	)	-RRB-
cord-315781-dejh8q22	143	6	.	.	.
cord-315781-dejh8q22	144	1	Swine	Swine	NNP
cord-315781-dejh8q22	144	2	may	may	MD
cord-315781-dejh8q22	144	3	be	be	VB
cord-315781-dejh8q22	144	4	the	the	DT
cord-315781-dejh8q22	144	5	origin	origin	NN
cord-315781-dejh8q22	144	6	of	of	IN
cord-315781-dejh8q22	144	7	the	the	DT
cord-315781-dejh8q22	144	8	1918	1918	CD
cord-315781-dejh8q22	144	9	pandemic	pandemic	NN
cord-315781-dejh8q22	144	10	virus	virus	NN
cord-315781-dejh8q22	144	11	,	,	,
cord-315781-dejh8q22	144	12	i.e.	i.e.	FW
cord-315781-dejh8q22	144	13	,	,	,
cord-315781-dejh8q22	144	14	the	the	DT
cord-315781-dejh8q22	144	15	1930	1930	CD
cord-315781-dejh8q22	144	16	swine	swine	NN
cord-315781-dejh8q22	144	17	strain	strain	NN
cord-315781-dejh8q22	144	18	may	may	MD
cord-315781-dejh8q22	144	19	be	be	VB
cord-315781-dejh8q22	144	20	a	a	DT
cord-315781-dejh8q22	144	21	derivative	derivative	NN
cord-315781-dejh8q22	144	22	of	of	IN
cord-315781-dejh8q22	144	23	this	this	DT
cord-315781-dejh8q22	144	24	group	group	NN
cord-315781-dejh8q22	144	25	of	of	IN
cord-315781-dejh8q22	144	26	viruses	virus	NNS
cord-315781-dejh8q22	144	27	.	.	.
cord-315781-dejh8q22	145	1	Drifts	drift	NNS
cord-315781-dejh8q22	145	2	and	and	CC
cord-315781-dejh8q22	145	3	spreading	spread	VBG
cord-315781-dejh8q22	145	4	:	:	:
cord-315781-dejh8q22	145	5	the	the	DT
cord-315781-dejh8q22	145	6	genomes	genome	NNS
cord-315781-dejh8q22	145	7	of	of	IN
cord-315781-dejh8q22	145	8	the	the	DT
cord-315781-dejh8q22	145	9	R	R	NNP
cord-315781-dejh8q22	145	10	group	group	NN
cord-315781-dejh8q22	145	11	of	of	IN
cord-315781-dejh8q22	145	12	human	human	JJ
cord-315781-dejh8q22	145	13	viruses	virus	NNS
cord-315781-dejh8q22	145	14	have	have	VBP
cord-315781-dejh8q22	145	15	been	be	VBN
cord-315781-dejh8q22	145	16	changing	change	VBG
cord-315781-dejh8q22	145	17	yearly	yearly	JJ
cord-315781-dejh8q22	145	18	(	(	-LRB-
cord-315781-dejh8q22	145	19	Figs	fig	NNS
cord-315781-dejh8q22	145	20	.	.	.
cord-315781-dejh8q22	146	1	2A	2a	LS
cord-315781-dejh8q22	146	2	-	-	HYPH
cord-315781-dejh8q22	146	3	C	C	NNP
cord-315781-dejh8q22	146	4	and	and	CC
cord-315781-dejh8q22	146	5	S4A	S4A	NNP
cord-315781-dejh8q22	146	6	)	)	-RRB-
cord-315781-dejh8q22	146	7	.	.	.
cord-315781-dejh8q22	147	1	The	the	DT
cord-315781-dejh8q22	147	2	changed	change	VBN
cord-315781-dejh8q22	147	3	residues	residue	NNS
cord-315781-dejh8q22	147	4	covered	cover	VBD
cord-315781-dejh8q22	147	5	almost	almost	RB
cord-315781-dejh8q22	147	6	the	the	DT
cord-315781-dejh8q22	147	7	whole	whole	JJ
cord-315781-dejh8q22	147	8	surface	surface	NN
cord-315781-dejh8q22	147	9	of	of	IN
cord-315781-dejh8q22	147	10	the	the	DT
cord-315781-dejh8q22	147	11	HA	HA	NNP
cord-315781-dejh8q22	147	12	protein	protein	NN
cord-315781-dejh8q22	147	13	(	(	-LRB-
cord-315781-dejh8q22	147	14	Fig	Fig	NNP
cord-315781-dejh8q22	147	15	.	.	.
cord-315781-dejh8q22	147	16	S3C	S3C	NNS
cord-315781-dejh8q22	147	17	)	)	-RRB-
cord-315781-dejh8q22	147	18	,	,	,
cord-315781-dejh8q22	147	19	showing	show	VBG
cord-315781-dejh8q22	147	20	the	the	DT
cord-315781-dejh8q22	147	21	trajectory	trajectory	NN
cord-315781-dejh8q22	147	22	of	of	IN
cord-315781-dejh8q22	147	23	the	the	DT
cord-315781-dejh8q22	147	24	30	30	CD
cord-315781-dejh8q22	147	25	years	year	NNS
cord-315781-dejh8q22	147	26	of	of	IN
cord-315781-dejh8q22	147	27	battle	battle	NN
cord-315781-dejh8q22	147	28	against	against	IN
cord-315781-dejh8q22	147	29	the	the	DT
cord-315781-dejh8q22	147	30	human	human	JJ
cord-315781-dejh8q22	147	31	immune	immune	NN
cord-315781-dejh8q22	147	32	system	system	NN
cord-315781-dejh8q22	147	33	.	.	.
cord-315781-dejh8q22	148	1	In	in	IN
cord-315781-dejh8q22	148	2	the	the	DT
cord-315781-dejh8q22	148	3	last	last	JJ
cord-315781-dejh8q22	148	4	few	few	JJ
cord-315781-dejh8q22	148	5	years	year	NNS
cord-315781-dejh8q22	148	6	,	,	,
cord-315781-dejh8q22	148	7	drifting	drifting	NN
cord-315781-dejh8q22	148	8	was	be	VBD
cord-315781-dejh8q22	148	9	not	not	RB
cord-315781-dejh8q22	148	10	observed	observe	VBN
cord-315781-dejh8q22	148	11	in	in	IN
cord-315781-dejh8q22	148	12	PC1	PC1	NNP
cord-315781-dejh8q22	148	13	,	,	,
cord-315781-dejh8q22	148	14	which	which	WDT
cord-315781-dejh8q22	148	15	records	record	VBZ
cord-315781-dejh8q22	148	16	positions	position	NNS
cord-315781-dejh8q22	148	17	that	that	WDT
cord-315781-dejh8q22	148	18	changed	change	VBD
cord-315781-dejh8q22	148	19	only	only	RB
cord-315781-dejh8q22	148	20	once	once	RB
cord-315781-dejh8q22	149	1	(	(	-LRB-
cord-315781-dejh8q22	149	2	Fig	Fig	NNP
cord-315781-dejh8q22	149	3	.	.	.
cord-315781-dejh8q22	149	4	2A	2a	CD
cord-315781-dejh8q22	149	5	,	,	,
cord-315781-dejh8q22	149	6	grey	grey	NNP
cord-315781-dejh8q22	149	7	)	)	-RRB-
cord-315781-dejh8q22	149	8	.	.	.
cord-315781-dejh8q22	150	1	It	-PRON-	PRP
cord-315781-dejh8q22	150	2	seems	seem	VBZ
cord-315781-dejh8q22	150	3	that	that	IN
cord-315781-dejh8q22	150	4	few	few	JJ
cord-315781-dejh8q22	150	5	positions	position	NNS
cord-315781-dejh8q22	150	6	that	that	WDT
cord-315781-dejh8q22	150	7	were	be	VBD
cord-315781-dejh8q22	150	8	amenable	amenable	JJ
cord-315781-dejh8q22	150	9	to	to	IN
cord-315781-dejh8q22	150	10	variation	variation	NN
cord-315781-dejh8q22	150	11	were	be	VBD
cord-315781-dejh8q22	150	12	left	leave	VBN
cord-315781-dejh8q22	150	13	unchanged	unchanged	JJ
cord-315781-dejh8q22	150	14	,	,	,
cord-315781-dejh8q22	150	15	and	and	CC
cord-315781-dejh8q22	150	16	that	that	IN
cord-315781-dejh8q22	150	17	spontaneous	spontaneous	JJ
cord-315781-dejh8q22	150	18	mutation	mutation	NN
cord-315781-dejh8q22	150	19	failed	fail	VBD
cord-315781-dejh8q22	150	20	to	to	TO
cord-315781-dejh8q22	150	21	hit	hit	VB
cord-315781-dejh8q22	150	22	those	those	DT
cord-315781-dejh8q22	150	23	positions	position	NNS
cord-315781-dejh8q22	150	24	(	(	-LRB-
cord-315781-dejh8q22	150	25	Fig	Fig	NNP
cord-315781-dejh8q22	150	26	.	.	.
cord-315781-dejh8q22	150	27	S3C	S3C	NNS
cord-315781-dejh8q22	150	28	,	,	,
cord-315781-dejh8q22	150	29	positions	position	NNS
cord-315781-dejh8q22	150	30	located	locate	VBN
cord-315781-dejh8q22	150	31	on	on	IN
cord-315781-dejh8q22	150	32	the	the	DT
cord-315781-dejh8q22	150	33	surface	surface	NN
cord-315781-dejh8q22	150	34	of	of	IN
cord-315781-dejh8q22	150	35	HA	HA	NNP
cord-315781-dejh8q22	150	36	and	and	CC
cord-315781-dejh8q22	150	37	not	not	RB
cord-315781-dejh8q22	150	38	marked	mark	VBN
cord-315781-dejh8q22	150	39	)	)	-RRB-
cord-315781-dejh8q22	150	40	.	.	.
cord-315781-dejh8q22	151	1	Even	even	RB
cord-315781-dejh8q22	151	2	the	the	DT
cord-315781-dejh8q22	151	3	viruses	virus	NNS
cord-315781-dejh8q22	151	4	that	that	WDT
cord-315781-dejh8q22	151	5	almost	almost	RB
cord-315781-dejh8q22	151	6	exhausted	exhaust	VBD
cord-315781-dejh8q22	151	7	the	the	DT
cord-315781-dejh8q22	151	8	number	number	NN
cord-315781-dejh8q22	151	9	of	of	IN
cord-315781-dejh8q22	151	10	unchanged	unchanged	JJ
cord-315781-dejh8q22	151	11	positions	position	NNS
cord-315781-dejh8q22	151	12	kept	keep	VBD
cord-315781-dejh8q22	151	13	drifting	drift	VBG
cord-315781-dejh8q22	151	14	in	in	IN
cord-315781-dejh8q22	151	15	the	the	DT
cord-315781-dejh8q22	151	16	lower	low	JJR
cord-315781-dejh8q22	151	17	PCs	pc	NNS
cord-315781-dejh8q22	151	18	,	,	,
cord-315781-dejh8q22	151	19	where	where	WRB
cord-315781-dejh8q22	151	20	repeated	repeat	VBN
cord-315781-dejh8q22	151	21	mutations	mutation	NNS
cord-315781-dejh8q22	151	22	were	be	VBD
cord-315781-dejh8q22	151	23	recorded	record	VBN
cord-315781-dejh8q22	151	24	(	(	-LRB-
cord-315781-dejh8q22	151	25	Fig	Fig	NNP
cord-315781-dejh8q22	151	26	.	.	.
cord-315781-dejh8q22	151	27	S4A	S4A	NNP
cord-315781-dejh8q22	151	28	)	)	-RRB-
cord-315781-dejh8q22	151	29	.	.	.
cord-315781-dejh8q22	152	1	The	the	DT
cord-315781-dejh8q22	152	2	leaps	leap	NNS
cord-315781-dejh8q22	152	3	of	of	IN
cord-315781-dejh8q22	152	4	drifting	drifting	NN
cord-315781-dejh8q22	152	5	observed	observe	VBN
cord-315781-dejh8q22	152	6	here	here	RB
cord-315781-dejh8q22	152	7	(	(	-LRB-
cord-315781-dejh8q22	152	8	Fig	Fig	NNP
cord-315781-dejh8q22	152	9	.	.	.
cord-315781-dejh8q22	152	10	2C	2C	NNP
cord-315781-dejh8q22	152	11	)	)	-RRB-
cord-315781-dejh8q22	152	12	may	may	MD
cord-315781-dejh8q22	152	13	not	not	RB
cord-315781-dejh8q22	152	14	denote	denote	VB
cord-315781-dejh8q22	152	15	punctuated	punctuated	JJ
cord-315781-dejh8q22	152	16	evolution	evolution	NN
cord-315781-dejh8q22	152	17	;	;	:
cord-315781-dejh8q22	152	18	rather	rather	RB
cord-315781-dejh8q22	152	19	,	,	,
cord-315781-dejh8q22	152	20	they	-PRON-	PRP
cord-315781-dejh8q22	152	21	may	may	MD
cord-315781-dejh8q22	152	22	be	be	VB
cord-315781-dejh8q22	152	23	the	the	DT
cord-315781-dejh8q22	152	24	result	result	NN
cord-315781-dejh8q22	152	25	of	of	IN
cord-315781-dejh8q22	152	26	accumulating	accumulate	VBG
cord-315781-dejh8q22	152	27	mutations	mutation	NNS
cord-315781-dejh8q22	152	28	that	that	WDT
cord-315781-dejh8q22	152	29	occurred	occur	VBD
cord-315781-dejh8q22	152	30	in	in	IN
cord-315781-dejh8q22	152	31	areas	area	NNS
cord-315781-dejh8q22	152	32	that	that	WDT
cord-315781-dejh8q22	152	33	do	do	VBP
cord-315781-dejh8q22	152	34	not	not	RB
cord-315781-dejh8q22	152	35	report	report	VB
cord-315781-dejh8q22	152	36	sequences	sequence	NNS
cord-315781-dejh8q22	152	37	.	.	.
cord-315781-dejh8q22	153	1	For	for	IN
cord-315781-dejh8q22	153	2	instance	instance	NN
cord-315781-dejh8q22	153	3	,	,	,
cord-315781-dejh8q22	153	4	very	very	RB
cord-315781-dejh8q22	153	5	few	few	JJ
cord-315781-dejh8q22	153	6	records	record	NNS
cord-315781-dejh8q22	153	7	are	be	VBP
cord-315781-dejh8q22	153	8	available	available	JJ
cord-315781-dejh8q22	153	9	from	from	IN
cord-315781-dejh8q22	153	10	the	the	DT
cord-315781-dejh8q22	153	11	African	african	JJ
cord-315781-dejh8q22	153	12	continent	continent	NN
cord-315781-dejh8q22	153	13	.	.	.
cord-315781-dejh8q22	154	1	The	the	DT
cord-315781-dejh8q22	154	2	history	history	NN
cord-315781-dejh8q22	154	3	of	of	IN
cord-315781-dejh8q22	154	4	the	the	DT
cord-315781-dejh8q22	154	5	R	r	NN
cord-315781-dejh8q22	154	6	type	type	NN
cord-315781-dejh8q22	154	7	also	also	RB
cord-315781-dejh8q22	154	8	included	include	VBD
cord-315781-dejh8q22	154	9	some	some	DT
cord-315781-dejh8q22	154	10	bifurcations	bifurcation	NNS
cord-315781-dejh8q22	154	11	(	(	-LRB-
cord-315781-dejh8q22	154	12	Fig	Fig	NNP
cord-315781-dejh8q22	154	13	.	.	.
cord-315781-dejh8q22	154	14	2A	2a	CD
cord-315781-dejh8q22	154	15	,	,	,
cord-315781-dejh8q22	154	16	C	C	NNP
cord-315781-dejh8q22	154	17	)	)	-RRB-
cord-315781-dejh8q22	154	18	;	;	:
cord-315781-dejh8q22	154	19	i.e.	i.e.	FW
cord-315781-dejh8q22	154	20	,	,	,
cord-315781-dejh8q22	154	21	viruses	virus	NNS
cord-315781-dejh8q22	154	22	located	locate	VBN
cord-315781-dejh8q22	154	23	on	on	IN
cord-315781-dejh8q22	154	24	different	different	JJ
cord-315781-dejh8q22	154	25	branches	branch	NNS
cord-315781-dejh8q22	154	26	appeared	appear	VBD
cord-315781-dejh8q22	154	27	in	in	IN
cord-315781-dejh8q22	154	28	different	different	JJ
cord-315781-dejh8q22	154	29	districts	district	NNS
cord-315781-dejh8q22	154	30	in	in	IN
cord-315781-dejh8q22	154	31	parallel	parallel	NN
cord-315781-dejh8q22	154	32	.	.	.
cord-315781-dejh8q22	155	1	If	if	IN
cord-315781-dejh8q22	155	2	these	these	DT
cord-315781-dejh8q22	155	3	viruses	virus	NNS
cord-315781-dejh8q22	155	4	competed	compete	VBD
cord-315781-dejh8q22	155	5	within	within	IN
cord-315781-dejh8q22	155	6	a	a	DT
cord-315781-dejh8q22	155	7	small	small	JJ
cord-315781-dejh8q22	155	8	area	area	NN
cord-315781-dejh8q22	155	9	,	,	,
cord-315781-dejh8q22	155	10	only	only	RB
cord-315781-dejh8q22	155	11	the	the	DT
cord-315781-dejh8q22	155	12	strain	strain	NN
cord-315781-dejh8q22	155	13	with	with	IN
cord-315781-dejh8q22	155	14	the	the	DT
cord-315781-dejh8q22	155	15	highest	high	JJS
cord-315781-dejh8q22	155	16	infectivity	infectivity	NN
cord-315781-dejh8q22	155	17	would	would	MD
cord-315781-dejh8q22	155	18	remain	remain	VB
cord-315781-dejh8q22	155	19	.	.	.
cord-315781-dejh8q22	156	1	If	if	IN
cord-315781-dejh8q22	156	2	some	some	DT
cord-315781-dejh8q22	156	3	drifts	drift	NNS
cord-315781-dejh8q22	156	4	occurred	occur	VBD
cord-315781-dejh8q22	156	5	coincidently	coincidently	RB
cord-315781-dejh8q22	156	6	in	in	IN
cord-315781-dejh8q22	156	7	areas	area	NNS
cord-315781-dejh8q22	156	8	located	locate	VBN
cord-315781-dejh8q22	156	9	far	far	RB
cord-315781-dejh8q22	156	10	apart	apart	RB
cord-315781-dejh8q22	156	11	,	,	,
cord-315781-dejh8q22	156	12	such	such	JJ
cord-315781-dejh8q22	156	13	branching	branching	NN
cord-315781-dejh8q22	156	14	might	may	MD
cord-315781-dejh8q22	156	15	have	have	VB
cord-315781-dejh8q22	156	16	occurred	occur	VBN
cord-315781-dejh8q22	156	17	and	and	CC
cord-315781-dejh8q22	156	18	might	may	MD
cord-315781-dejh8q22	156	19	have	have	VB
cord-315781-dejh8q22	156	20	been	be	VBN
cord-315781-dejh8q22	156	21	maintained	maintain	VBN
cord-315781-dejh8q22	156	22	for	for	IN
cord-315781-dejh8q22	156	23	a	a	DT
cord-315781-dejh8q22	156	24	while	while	NN
cord-315781-dejh8q22	156	25	.	.	.
cord-315781-dejh8q22	157	1	In	in	IN
cord-315781-dejh8q22	157	2	contrast	contrast	NN
cord-315781-dejh8q22	157	3	to	to	IN
cord-315781-dejh8q22	157	4	the	the	DT
cord-315781-dejh8q22	157	5	frequent	frequent	JJ
cord-315781-dejh8q22	157	6	drifts	drift	NNS
cord-315781-dejh8q22	157	7	observed	observe	VBN
cord-315781-dejh8q22	157	8	in	in	IN
cord-315781-dejh8q22	157	9	the	the	DT
cord-315781-dejh8q22	157	10	human	human	JJ
cord-315781-dejh8q22	157	11	strains	strain	NNS
cord-315781-dejh8q22	157	12	,	,	,
cord-315781-dejh8q22	157	13	those	those	DT
cord-315781-dejh8q22	157	14	of	of	IN
cord-315781-dejh8q22	157	15	livestock	livestock	NN
cord-315781-dejh8q22	157	16	seemed	seem	VBD
cord-315781-dejh8q22	157	17	to	to	TO
cord-315781-dejh8q22	157	18	be	be	VB
cord-315781-dejh8q22	157	19	conserved	conserve	VBN
cord-315781-dejh8q22	157	20	.	.	.
cord-315781-dejh8q22	158	1	The	the	DT
cord-315781-dejh8q22	158	2	livestock	livestock	NN
cord-315781-dejh8q22	158	3	strains	strain	NNS
cord-315781-dejh8q22	158	4	differed	differ	VBD
cord-315781-dejh8q22	158	5	among	among	IN
cord-315781-dejh8q22	158	6	districts	district	NNS
cord-315781-dejh8q22	158	7	and	and	CC
cord-315781-dejh8q22	158	8	remained	remain	VBD
cord-315781-dejh8q22	158	9	constant	constant	JJ
cord-315781-dejh8q22	158	10	for	for	IN
cord-315781-dejh8q22	158	11	years	year	NNS
cord-315781-dejh8q22	158	12	.	.	.
cord-315781-dejh8q22	159	1	The	the	DT
cord-315781-dejh8q22	159	2	conservative	conservative	JJ
cord-315781-dejh8q22	159	3	nature	nature	NN
cord-315781-dejh8q22	159	4	of	of	IN
cord-315781-dejh8q22	159	5	these	these	DT
cord-315781-dejh8q22	159	6	viral	viral	JJ
cord-315781-dejh8q22	159	7	sequences	sequence	NNS
cord-315781-dejh8q22	159	8	may	may	MD
cord-315781-dejh8q22	159	9	be	be	VB
cord-315781-dejh8q22	159	10	attributed	attribute	VBN
cord-315781-dejh8q22	159	11	to	to	IN
cord-315781-dejh8q22	159	12	the	the	DT
cord-315781-dejh8q22	159	13	short	short	JJ
cord-315781-dejh8q22	159	14	life	life	NN
cord-315781-dejh8q22	159	15	-	-	HYPH
cord-315781-dejh8q22	159	16	span	span	NN
cord-315781-dejh8q22	159	17	of	of	IN
cord-315781-dejh8q22	159	18	livestock	livestock	NN
cord-315781-dejh8q22	159	19	.	.	.
cord-315781-dejh8q22	160	1	As	as	IN
cord-315781-dejh8q22	160	2	they	-PRON-	PRP
cord-315781-dejh8q22	160	3	rarely	rarely	RB
cord-315781-dejh8q22	160	4	live	live	VBP
cord-315781-dejh8q22	160	5	for	for	IN
cord-315781-dejh8q22	160	6	a	a	DT
cord-315781-dejh8q22	160	7	year	year	NN
cord-315781-dejh8q22	160	8	,	,	,
cord-315781-dejh8q22	160	9	they	-PRON-	PRP
cord-315781-dejh8q22	160	10	are	be	VBP
cord-315781-dejh8q22	160	11	not	not	RB
cord-315781-dejh8q22	160	12	immune	immune	JJ
cord-315781-dejh8q22	160	13	to	to	IN
cord-315781-dejh8q22	160	14	viruses	virus	NNS
cord-315781-dejh8q22	160	15	that	that	WDT
cord-315781-dejh8q22	160	16	spread	spread	VBD
cord-315781-dejh8q22	160	17	over	over	IN
cord-315781-dejh8q22	160	18	the	the	DT
cord-315781-dejh8q22	160	19	previous	previous	JJ
cord-315781-dejh8q22	160	20	year	year	NN
cord-315781-dejh8q22	160	21	.	.	.
cord-315781-dejh8q22	161	1	Hence	hence	RB
cord-315781-dejh8q22	161	2	,	,	,
cord-315781-dejh8q22	161	3	these	these	DT
cord-315781-dejh8q22	161	4	viruses	virus	NNS
cord-315781-dejh8q22	161	5	are	be	VBP
cord-315781-dejh8q22	161	6	not	not	RB
cord-315781-dejh8q22	161	7	under	under	IN
cord-315781-dejh8q22	161	8	a	a	DT
cord-315781-dejh8q22	161	9	selective	selective	JJ
cord-315781-dejh8q22	161	10	pressure	pressure	NN
cord-315781-dejh8q22	161	11	toward	toward	IN
cord-315781-dejh8q22	161	12	the	the	DT
cord-315781-dejh8q22	161	13	formation	formation	NN
cord-315781-dejh8q22	161	14	of	of	IN
cord-315781-dejh8q22	161	15	newer	new	JJR
cord-315781-dejh8q22	161	16	epitopes	epitope	NNS
cord-315781-dejh8q22	161	17	.	.	.
cord-315781-dejh8q22	162	1	Likely	likely	RB
cord-315781-dejh8q22	162	2	,	,	,
cord-315781-dejh8q22	162	3	a	a	DT
cord-315781-dejh8q22	162	4	conservative	conservative	JJ
cord-315781-dejh8q22	162	5	character	character	NN
cord-315781-dejh8q22	162	6	was	be	VBD
cord-315781-dejh8q22	162	7	also	also	RB
cord-315781-dejh8q22	162	8	found	find	VBN
cord-315781-dejh8q22	162	9	in	in	IN
cord-315781-dejh8q22	162	10	our	-PRON-	PRP$
cord-315781-dejh8q22	162	11	preliminary	preliminary	JJ
cord-315781-dejh8q22	162	12	studies	study	NNS
cord-315781-dejh8q22	162	13	of	of	IN
cord-315781-dejh8q22	162	14	human	human	JJ
cord-315781-dejh8q22	162	15	infection	infection	NN
cord-315781-dejh8q22	162	16	with	with	IN
cord-315781-dejh8q22	162	17	filoviruses	filovirus	NNS
cord-315781-dejh8q22	162	18	and	and	CC
cord-315781-dejh8q22	162	19	coronaviruses	coronaviruse	NNS
cord-315781-dejh8q22	162	20	(	(	-LRB-
cord-315781-dejh8q22	162	21	not	not	RB
cord-315781-dejh8q22	162	22	shown	show	VBN
cord-315781-dejh8q22	162	23	)	)	-RRB-
cord-315781-dejh8q22	162	24	.	.	.
cord-315781-dejh8q22	163	1	Moreover	moreover	RB
cord-315781-dejh8q22	163	2	,	,	,
cord-315781-dejh8q22	163	3	because	because	IN
cord-315781-dejh8q22	163	4	livestock	livestock	NN
cord-315781-dejh8q22	163	5	rarely	rarely	RB
cord-315781-dejh8q22	163	6	move	move	VBP
cord-315781-dejh8q22	163	7	around	around	RB
cord-315781-dejh8q22	163	8	,	,	,
cord-315781-dejh8q22	163	9	the	the	DT
cord-315781-dejh8q22	163	10	area	area	NN
cord-315781-dejh8q22	163	11	of	of	IN
cord-315781-dejh8q22	163	12	viral	viral	JJ
cord-315781-dejh8q22	163	13	transmission	transmission	NN
cord-315781-dejh8q22	163	14	is	be	VBZ
cord-315781-dejh8q22	163	15	limited	limit	VBN
cord-315781-dejh8q22	163	16	.	.	.
cord-315781-dejh8q22	164	1	For	for	IN
cord-315781-dejh8q22	164	2	example	example	NN
cord-315781-dejh8q22	164	3	,	,	,
cord-315781-dejh8q22	164	4	even	even	RB
cord-315781-dejh8q22	164	5	the	the	DT
cord-315781-dejh8q22	164	6	very	very	RB
cord-315781-dejh8q22	164	7	infectious	infectious	JJ
cord-315781-dejh8q22	164	8	pandemic	pandemic	NN
cord-315781-dejh8q22	164	9	avian	avian	JJ
cord-315781-dejh8q22	164	10	virus	virus	NN
cord-315781-dejh8q22	164	11	of	of	IN
cord-315781-dejh8q22	164	12	2004	2004	CD
cord-315781-dejh8q22	164	13	was	be	VBD
cord-315781-dejh8q22	164	14	unable	unable	JJ
cord-315781-dejh8q22	164	15	to	to	TO
cord-315781-dejh8q22	164	16	spread	spread	VB
cord-315781-dejh8q22	164	17	worldwide	worldwide	RB
cord-315781-dejh8q22	164	18	.	.	.
cord-315781-dejh8q22	165	1	Instead	instead	RB
cord-315781-dejh8q22	165	2	,	,	,
cord-315781-dejh8q22	165	3	it	-PRON-	PRP
cord-315781-dejh8q22	165	4	infected	infect	VBD
cord-315781-dejh8q22	165	5	a	a	DT
cord-315781-dejh8q22	165	6	limited	limited	JJ
cord-315781-dejh8q22	165	7	number	number	NN
cord-315781-dejh8q22	165	8	of	of	IN
cord-315781-dejh8q22	165	9	farms	farm	NNS
cord-315781-dejh8q22	165	10	2	2	CD
cord-315781-dejh8q22	165	11	.	.	.
cord-315781-dejh8q22	166	1	This	this	DT
cord-315781-dejh8q22	166	2	limitation	limitation	NN
cord-315781-dejh8q22	166	3	precludes	preclude	VBZ
cord-315781-dejh8q22	166	4	a	a	DT
cord-315781-dejh8q22	166	5	competition	competition	NN
cord-315781-dejh8q22	166	6	among	among	IN
cord-315781-dejh8q22	166	7	strains	strain	NNS
cord-315781-dejh8q22	166	8	,	,	,
cord-315781-dejh8q22	166	9	which	which	WDT
cord-315781-dejh8q22	166	10	enabling	enable	VBG
cord-315781-dejh8q22	166	11	the	the	DT
cord-315781-dejh8q22	166	12	maintenance	maintenance	NN
cord-315781-dejh8q22	166	13	of	of	IN
cord-315781-dejh8q22	166	14	unique	unique	JJ
cord-315781-dejh8q22	166	15	strains	strain	NNS
cord-315781-dejh8q22	166	16	in	in	IN
cord-315781-dejh8q22	166	17	small	small	JJ
cord-315781-dejh8q22	166	18	,	,	,
cord-315781-dejh8q22	166	19	separate	separate	JJ
cord-315781-dejh8q22	166	20	areas	area	NNS
cord-315781-dejh8q22	166	21	.	.	.
cord-315781-dejh8q22	167	1	Some	some	DT
cord-315781-dejh8q22	167	2	of	of	IN
cord-315781-dejh8q22	167	3	the	the	DT
cord-315781-dejh8q22	167	4	strains	strain	NNS
cord-315781-dejh8q22	167	5	that	that	WDT
cord-315781-dejh8q22	167	6	are	be	VBP
cord-315781-dejh8q22	167	7	retained	retain	VBN
cord-315781-dejh8q22	167	8	may	may	MD
cord-315781-dejh8q22	167	9	include	include	VB
cord-315781-dejh8q22	167	10	segments	segment	NNS
cord-315781-dejh8q22	167	11	that	that	WDT
cord-315781-dejh8q22	167	12	spread	spread	VBD
cord-315781-dejh8q22	167	13	among	among	IN
cord-315781-dejh8q22	167	14	humans	human	NNS
cord-315781-dejh8q22	167	15	in	in	IN
cord-315781-dejh8q22	167	16	the	the	DT
cord-315781-dejh8q22	167	17	past	past	NN
cord-315781-dejh8q22	167	18	.	.	.
cord-315781-dejh8q22	168	1	It	-PRON-	PRP
cord-315781-dejh8q22	168	2	is	be	VBZ
cord-315781-dejh8q22	168	3	even	even	RB
cord-315781-dejh8q22	168	4	possible	possible	JJ
cord-315781-dejh8q22	168	5	that	that	IN
cord-315781-dejh8q22	168	6	several	several	JJ
cord-315781-dejh8q22	168	7	human	human	JJ
cord-315781-dejh8q22	168	8	viruses	virus	NNS
cord-315781-dejh8q22	168	9	are	be	VBP
cord-315781-dejh8q22	168	10	kept	keep	VBN
cord-315781-dejh8q22	168	11	intact	intact	JJ
cord-315781-dejh8q22	168	12	among	among	IN
cord-315781-dejh8q22	168	13	swine	swine	NN
cord-315781-dejh8q22	168	14	.	.	.
cord-315781-dejh8q22	169	1	Such	such	JJ
cord-315781-dejh8q22	169	2	collections	collection	NNS
cord-315781-dejh8q22	169	3	may	may	MD
cord-315781-dejh8q22	169	4	be	be	VB
cord-315781-dejh8q22	169	5	the	the	DT
cord-315781-dejh8q22	169	6	source	source	NN
cord-315781-dejh8q22	169	7	of	of	IN
cord-315781-dejh8q22	169	8	the	the	DT
cord-315781-dejh8q22	169	9	1977	1977	CD
cord-315781-dejh8q22	169	10	pandemic	pandemic	NN
cord-315781-dejh8q22	169	11	virus	virus	NN
cord-315781-dejh8q22	169	12	,	,	,
cord-315781-dejh8q22	169	13	which	which	WDT
cord-315781-dejh8q22	169	14	is	be	VBZ
cord-315781-dejh8q22	169	15	thought	think	VBN
cord-315781-dejh8q22	169	16	to	to	TO
cord-315781-dejh8q22	169	17	be	be	VB
cord-315781-dejh8q22	169	18	a	a	DT
cord-315781-dejh8q22	169	19	frozen	frozen	JJ
cord-315781-dejh8q22	169	20	laboratory	laboratory	NN
cord-315781-dejh8q22	169	21	strain	strain	NN
cord-315781-dejh8q22	169	22	that	that	WDT
cord-315781-dejh8q22	169	23	was	be	VBD
cord-315781-dejh8q22	169	24	released	release	VBN
cord-315781-dejh8q22	169	25	accidentally	accidentally	RB
cord-315781-dejh8q22	169	26	4	4	CD
cord-315781-dejh8q22	169	27	,	,	,
cord-315781-dejh8q22	169	28	18	18	CD
cord-315781-dejh8q22	169	29	.	.	.
cord-315781-dejh8q22	170	1	The	the	DT
cord-315781-dejh8q22	170	2	migration	migration	NN
cord-315781-dejh8q22	170	3	of	of	IN
cord-315781-dejh8q22	170	4	livestock	livestock	NN
cord-315781-dejh8q22	170	5	viruses	virus	NNS
cord-315781-dejh8q22	170	6	could	could	MD
cord-315781-dejh8q22	170	7	be	be	VB
cord-315781-dejh8q22	170	8	mainly	mainly	RB
cord-315781-dejh8q22	170	9	caused	cause	VBN
cord-315781-dejh8q22	170	10	by	by	IN
cord-315781-dejh8q22	170	11	trading	trade	VBG
cord-315781-dejh8q22	170	12	11	11	CD
cord-315781-dejh8q22	170	13	,	,	,
cord-315781-dejh8q22	170	14	although	although	IN
cord-315781-dejh8q22	170	15	migrant	migrant	JJ
cord-315781-dejh8q22	170	16	birds	bird	NNS
cord-315781-dejh8q22	170	17	might	may	MD
cord-315781-dejh8q22	170	18	be	be	VB
cord-315781-dejh8q22	170	19	able	able	JJ
cord-315781-dejh8q22	170	20	to	to	TO
cord-315781-dejh8q22	170	21	transport	transport	VB
cord-315781-dejh8q22	170	22	avian	avian	JJ
cord-315781-dejh8q22	170	23	viruses	virus	NNS
cord-315781-dejh8q22	170	24	to	to	IN
cord-315781-dejh8q22	170	25	chickens	chicken	NNS
cord-315781-dejh8q22	170	26	in	in	IN
cord-315781-dejh8q22	170	27	some	some	DT
cord-315781-dejh8q22	170	28	cases	case	NNS
cord-315781-dejh8q22	170	29	19	19	CD
cord-315781-dejh8q22	170	30	.	.	.
cord-315781-dejh8q22	171	1	However	however	RB
cord-315781-dejh8q22	171	2	,	,	,
cord-315781-dejh8q22	171	3	if	if	IN
cord-315781-dejh8q22	171	4	such	such	JJ
cord-315781-dejh8q22	171	5	transfers	transfer	NNS
cord-315781-dejh8q22	171	6	occur	occur	VBP
cord-315781-dejh8q22	171	7	frequently	frequently	RB
cord-315781-dejh8q22	171	8	,	,	,
cord-315781-dejh8q22	171	9	the	the	DT
cord-315781-dejh8q22	171	10	characteristics	characteristic	NNS
cord-315781-dejh8q22	171	11	of	of	IN
cord-315781-dejh8q22	171	12	specific	specific	JJ
cord-315781-dejh8q22	171	13	areas	area	NNS
cord-315781-dejh8q22	171	14	would	would	MD
cord-315781-dejh8q22	171	15	disappear	disappear	VB
cord-315781-dejh8q22	171	16	,	,	,
cord-315781-dejh8q22	171	17	and	and	CC
cord-315781-dejh8q22	171	18	viruses	virus	NNS
cord-315781-dejh8q22	171	19	would	would	MD
cord-315781-dejh8q22	171	20	be	be	VB
cord-315781-dejh8q22	171	21	better	well	RBR
cord-315781-dejh8q22	171	22	distributed	distribute	VBN
cord-315781-dejh8q22	171	23	worldwide	worldwide	RB
cord-315781-dejh8q22	171	24	;	;	:
cord-315781-dejh8q22	171	25	in	in	IN
cord-315781-dejh8q22	171	26	particular	particular	JJ
cord-315781-dejh8q22	171	27	,	,	,
cord-315781-dejh8q22	171	28	Europe	Europe	NNP
cord-315781-dejh8q22	171	29	www.nature.com/scientificreports	www.nature.com/scientificreport	VBZ
cord-315781-dejh8q22	172	1	www.nature.com/scientificreports/	www.nature.com/scientificreports/	NNP
cord-315781-dejh8q22	172	2	should	should	MD
cord-315781-dejh8q22	172	3	have	have	VB
cord-315781-dejh8q22	172	4	viruses	virus	NNS
cord-315781-dejh8q22	172	5	that	that	WDT
cord-315781-dejh8q22	172	6	originated	originate	VBD
cord-315781-dejh8q22	172	7	in	in	IN
cord-315781-dejh8q22	172	8	other	other	JJ
cord-315781-dejh8q22	172	9	areas	area	NNS
cord-315781-dejh8q22	172	10	(	(	-LRB-
cord-315781-dejh8q22	172	11	Fig	fig	NN
cord-315781-dejh8q22	172	12	.	.	.
cord-315781-dejh8q22	172	13	S2	S2	NNP
cord-315781-dejh8q22	172	14	)	)	-RRB-
cord-315781-dejh8q22	172	15	.	.	.
cord-315781-dejh8q22	173	1	Therefore	therefore	RB
cord-315781-dejh8q22	173	2	,	,	,
cord-315781-dejh8q22	173	3	viruses	virus	NNS
cord-315781-dejh8q22	173	4	of	of	IN
cord-315781-dejh8q22	173	5	livestock	livestock	NN
cord-315781-dejh8q22	173	6	would	would	MD
cord-315781-dejh8q22	173	7	be	be	VB
cord-315781-dejh8q22	173	8	transmitted	transmit	VBN
cord-315781-dejh8q22	173	9	rarely	rarely	RB
cord-315781-dejh8q22	173	10	by	by	IN
cord-315781-dejh8q22	173	11	migrant	migrant	JJ
cord-315781-dejh8q22	173	12	birds	bird	NNS
cord-315781-dejh8q22	173	13	.	.	.
cord-315781-dejh8q22	174	1	We	-PRON-	PRP
cord-315781-dejh8q22	174	2	should	should	MD
cord-315781-dejh8q22	174	3	be	be	VB
cord-315781-dejh8q22	174	4	aware	aware	JJ
cord-315781-dejh8q22	174	5	of	of	IN
cord-315781-dejh8q22	174	6	the	the	DT
cord-315781-dejh8q22	174	7	risk	risk	NN
cord-315781-dejh8q22	174	8	of	of	IN
cord-315781-dejh8q22	174	9	keeping	keep	VBG
cord-315781-dejh8q22	174	10	groups	group	NNS
cord-315781-dejh8q22	174	11	of	of	IN
cord-315781-dejh8q22	174	12	swine	swine	NN
cord-315781-dejh8q22	174	13	that	that	WDT
cord-315781-dejh8q22	174	14	have	have	VBP
cord-315781-dejh8q22	174	15	different	different	JJ
cord-315781-dejh8q22	174	16	influenza	influenza	NN
cord-315781-dejh8q22	174	17	strains	strain	NNS
cord-315781-dejh8q22	174	18	in	in	IN
cord-315781-dejh8q22	174	19	adjacent	adjacent	JJ
cord-315781-dejh8q22	174	20	farms	farm	NNS
cord-315781-dejh8q22	174	21	because	because	IN
cord-315781-dejh8q22	174	22	new	new	JJ
cord-315781-dejh8q22	174	23	viruses	virus	NNS
cord-315781-dejh8q22	174	24	may	may	MD
cord-315781-dejh8q22	174	25	be	be	VB
cord-315781-dejh8q22	174	26	produced	produce	VBN
cord-315781-dejh8q22	174	27	by	by	IN
cord-315781-dejh8q22	174	28	genome	genome	NN
cord-315781-dejh8q22	174	29	shifting	shifting	NN
cord-315781-dejh8q22	174	30	.	.	.
cord-315781-dejh8q22	175	1	To	to	TO
cord-315781-dejh8q22	175	2	prevent	prevent	VB
cord-315781-dejh8q22	175	3	this	this	DT
cord-315781-dejh8q22	175	4	,	,	,
cord-315781-dejh8q22	175	5	the	the	DT
cord-315781-dejh8q22	175	6	segregation	segregation	NN
cord-315781-dejh8q22	175	7	of	of	IN
cord-315781-dejh8q22	175	8	imported	import	VBN
cord-315781-dejh8q22	175	9	swine	swine	NN
cord-315781-dejh8q22	175	10	from	from	IN
cord-315781-dejh8q22	175	11	domestic	domestic	JJ
cord-315781-dejh8q22	175	12	ones	one	NNS
cord-315781-dejh8q22	175	13	is	be	VBZ
cord-315781-dejh8q22	175	14	critical	critical	JJ
cord-315781-dejh8q22	175	15	.	.	.
cord-315781-dejh8q22	176	1	Districts	district	NNS
cord-315781-dejh8q22	176	2	that	that	WDT
cord-315781-dejh8q22	176	3	report	report	VBP
cord-315781-dejh8q22	176	4	several	several	JJ
cord-315781-dejh8q22	176	5	viral	viral	JJ
cord-315781-dejh8q22	176	6	types	type	NNS
cord-315781-dejh8q22	176	7	should	should	MD
cord-315781-dejh8q22	176	8	prevent	prevent	VB
cord-315781-dejh8q22	176	9	farm	farm	NN
cord-315781-dejh8q22	176	10	-	-	HYPH
cord-315781-dejh8q22	176	11	to	to	IN
cord-315781-dejh8q22	176	12	-	-	HYPH
cord-315781-dejh8q22	176	13	farm	farm	NN
cord-315781-dejh8q22	176	14	contamination	contamination	NN
cord-315781-dejh8q22	176	15	.	.	.
cord-315781-dejh8q22	177	1	Moreover	moreover	RB
cord-315781-dejh8q22	177	2	,	,	,
cord-315781-dejh8q22	177	3	the	the	DT
cord-315781-dejh8q22	177	4	exchange	exchange	NN
cord-315781-dejh8q22	177	5	of	of	IN
cord-315781-dejh8q22	177	6	genomes	genome	NNS
cord-315781-dejh8q22	177	7	between	between	IN
cord-315781-dejh8q22	177	8	human	human	NN
cord-315781-dejh8q22	177	9	and	and	CC
cord-315781-dejh8q22	177	10	swine	swine	NN
cord-315781-dejh8q22	177	11	viruses	virus	NNS
cord-315781-dejh8q22	177	12	may	may	MD
cord-315781-dejh8q22	177	13	give	give	VB
cord-315781-dejh8q22	177	14	rise	rise	NN
cord-315781-dejh8q22	177	15	to	to	IN
cord-315781-dejh8q22	177	16	a	a	DT
cord-315781-dejh8q22	177	17	new	new	JJ
cord-315781-dejh8q22	177	18	strain	strain	NN
cord-315781-dejh8q22	177	19	with	with	IN
cord-315781-dejh8q22	177	20	new	new	JJ
cord-315781-dejh8q22	177	21	sets	set	NNS
cord-315781-dejh8q22	177	22	of	of	IN
cord-315781-dejh8q22	177	23	surface	surface	NN
cord-315781-dejh8q22	177	24	proteins	protein	NNS
cord-315781-dejh8q22	177	25	that	that	WDT
cord-315781-dejh8q22	177	26	is	be	VBZ
cord-315781-dejh8q22	177	27	able	able	JJ
cord-315781-dejh8q22	177	28	to	to	TO
cord-315781-dejh8q22	177	29	infect	infect	VB
cord-315781-dejh8q22	177	30	humans	human	NNS
cord-315781-dejh8q22	177	31	.	.	.
cord-315781-dejh8q22	178	1	The	the	DT
cord-315781-dejh8q22	178	2	Switzerland	Switzerland	NNP
cord-315781-dejh8q22	178	3	virus	virus	NN
cord-315781-dejh8q22	178	4	(	(	-LRB-
cord-315781-dejh8q22	178	5	NCBI	NCBI	NNP
cord-315781-dejh8q22	178	6	taxonomy	taxonomy	NN
cord-315781-dejh8q22	178	7	ID	ID	NNP
cord-315781-dejh8q22	178	8	:	:	:
cord-315781-dejh8q22	178	9	940568	940568	CD
cord-315781-dejh8q22	178	10	)	)	-RRB-
cord-315781-dejh8q22	178	11	proved	prove	VBD
cord-315781-dejh8q22	178	12	that	that	IN
cord-315781-dejh8q22	178	13	the	the	DT
cord-315781-dejh8q22	178	14	group	group	NN
cord-315781-dejh8q22	178	15	U	u	NN
cord-315781-dejh8q22	178	16	strain	strain	NN
cord-315781-dejh8q22	178	17	is	be	VBZ
cord-315781-dejh8q22	178	18	also	also	RB
cord-315781-dejh8q22	178	19	capable	capable	JJ
cord-315781-dejh8q22	178	20	of	of	IN
cord-315781-dejh8q22	178	21	infecting	infect	VBG
cord-315781-dejh8q22	178	22	humans	human	NNS
cord-315781-dejh8q22	178	23	;	;	:
cord-315781-dejh8q22	178	24	therefore	therefore	RB
cord-315781-dejh8q22	178	25	,	,	,
cord-315781-dejh8q22	178	26	a	a	DT
cord-315781-dejh8q22	178	27	new	new	JJ
cord-315781-dejh8q22	178	28	pandemic	pandemic	NN
cord-315781-dejh8q22	178	29	may	may	MD
cord-315781-dejh8q22	178	30	occur	occur	VB
cord-315781-dejh8q22	178	31	in	in	IN
cord-315781-dejh8q22	178	32	the	the	DT
cord-315781-dejh8q22	178	33	case	case	NN
cord-315781-dejh8q22	178	34	of	of	IN
cord-315781-dejh8q22	178	35	an	an	DT
cord-315781-dejh8q22	178	36	outbreak	outbreak	NN
cord-315781-dejh8q22	178	37	of	of	IN
cord-315781-dejh8q22	178	38	this	this	DT
cord-315781-dejh8q22	178	39	type	type	NN
cord-315781-dejh8q22	178	40	of	of	IN
cord-315781-dejh8q22	178	41	virus	virus	NN
cord-315781-dejh8q22	178	42	.	.	.
cord-315781-dejh8q22	179	1	Such	such	JJ
cord-315781-dejh8q22	179	2	viruses	virus	NNS
cord-315781-dejh8q22	179	3	of	of	IN
cord-315781-dejh8q22	179	4	human	human	JJ
cord-315781-dejh8q22	179	5	origin	origin	NN
cord-315781-dejh8q22	179	6	are	be	VBP
cord-315781-dejh8q22	179	7	maintained	maintain	VBN
cord-315781-dejh8q22	179	8	among	among	IN
cord-315781-dejh8q22	179	9	swine	swine	NN
cord-315781-dejh8q22	179	10	,	,	,
cord-315781-dejh8q22	179	11	maybe	maybe	RB
cord-315781-dejh8q22	179	12	latently	latently	RB
cord-315781-dejh8q22	179	13	(	(	-LRB-
cord-315781-dejh8q22	179	14	Fig	Fig	NNP
cord-315781-dejh8q22	179	15	.	.	.
cord-315781-dejh8q22	179	16	3A	3A	NNP
cord-315781-dejh8q22	179	17	,	,	,
cord-315781-dejh8q22	179	18	B	B	NNP
cord-315781-dejh8q22	179	19	)	)	-RRB-
cord-315781-dejh8q22	179	20	.	.	.
cord-315781-dejh8q22	180	1	Origins	origin	NNS
cord-315781-dejh8q22	180	2	of	of	IN
cord-315781-dejh8q22	180	3	the	the	DT
cord-315781-dejh8q22	180	4	segments	segment	NNS
cord-315781-dejh8q22	180	5	:	:	:
cord-315781-dejh8q22	180	6	the	the	DT
cord-315781-dejh8q22	180	7	pdm09	pdm09	NNP
cord-315781-dejh8q22	180	8	virus	virus	NN
cord-315781-dejh8q22	180	9	may	may	MD
cord-315781-dejh8q22	180	10	have	have	VB
cord-315781-dejh8q22	180	11	originated	originate	VBN
cord-315781-dejh8q22	180	12	via	via	IN
cord-315781-dejh8q22	180	13	shifts	shift	NNS
cord-315781-dejh8q22	180	14	among	among	IN
cord-315781-dejh8q22	180	15	swine	swine	NN
cord-315781-dejh8q22	180	16	viruses	virus	NNS
cord-315781-dejh8q22	180	17	8	8	CD
cord-315781-dejh8q22	180	18	,	,	,
cord-315781-dejh8q22	180	19	10	10	CD
cord-315781-dejh8q22	180	20	,	,	,
cord-315781-dejh8q22	180	21	11	11	CD
cord-315781-dejh8q22	180	22	.	.	.
cord-315781-dejh8q22	181	1	The	the	DT
cord-315781-dejh8q22	181	2	American	american	JJ
cord-315781-dejh8q22	181	3	classic	classic	JJ
cord-315781-dejh8q22	181	4	virus	virus	NN
cord-315781-dejh8q22	181	5	and	and	CC
cord-315781-dejh8q22	181	6	the	the	DT
cord-315781-dejh8q22	181	7	reassortant	reassortant	JJ
cord-315781-dejh8q22	181	8	virus	virus	NN
cord-315781-dejh8q22	181	9	could	could	MD
cord-315781-dejh8q22	181	10	be	be	VB
cord-315781-dejh8q22	181	11	defined	define	VBN
cord-315781-dejh8q22	181	12	using	use	VBG
cord-315781-dejh8q22	181	13	the	the	DT
cord-315781-dejh8q22	181	14	segments	segment	NNS
cord-315781-dejh8q22	181	15	(	(	-LRB-
cord-315781-dejh8q22	181	16	R	r	NN
cord-315781-dejh8q22	181	17	,	,	,
cord-315781-dejh8q22	181	18	R	r	NN
cord-315781-dejh8q22	181	19	(	(	-LRB-
cord-315781-dejh8q22	181	20	Table	table	NN
cord-315781-dejh8q22	181	21	1	1	CD
cord-315781-dejh8q22	181	22	)	)	-RRB-
cord-315781-dejh8q22	181	23	.	.	.
cord-315781-dejh8q22	182	1	Replacing	replace	VBG
cord-315781-dejh8q22	182	2	the	the	DT
cord-315781-dejh8q22	182	3	U	U	NNP
cord-315781-dejh8q22	182	4	groups	group	NNS
cord-315781-dejh8q22	182	5	of	of	IN
cord-315781-dejh8q22	182	6	NA	NA	NNP
cord-315781-dejh8q22	182	7	and	and	CC
cord-315781-dejh8q22	182	8	MP	MP	NNP
cord-315781-dejh8q22	182	9	with	with	IN
cord-315781-dejh8q22	182	10	those	those	DT
cord-315781-dejh8q22	182	11	of	of	IN
cord-315781-dejh8q22	182	12	the	the	DT
cord-315781-dejh8q22	182	13	European	european	JJ
cord-315781-dejh8q22	182	14	type	type	NN
cord-315781-dejh8q22	182	15	(	(	-LRB-
cord-315781-dejh8q22	182	16	U	u	UH
cord-315781-dejh8q22	182	17	,	,	,
cord-315781-dejh8q22	182	18	U	u	UH
cord-315781-dejh8q22	182	19	,	,	,
cord-315781-dejh8q22	182	20	U	u	UH
cord-315781-dejh8q22	182	21	,	,	,
cord-315781-dejh8q22	182	22	U	u	UH
cord-315781-dejh8q22	182	23	,	,	,
cord-315781-dejh8q22	182	24	U	U	NNP
cord-315781-dejh8q22	182	25	,	,	,
cord-315781-dejh8q22	182	26	M	M	NNP
cord-315781-dejh8q22	182	27	,	,	,
cord-315781-dejh8q22	182	28	M	M	NNP
cord-315781-dejh8q22	182	29	,	,	,
cord-315781-dejh8q22	182	30	U	U	NNP
cord-315781-dejh8q22	182	31	)	)	-RRB-
cord-315781-dejh8q22	182	32	can	can	MD
cord-315781-dejh8q22	182	33	complete	complete	VB
cord-315781-dejh8q22	182	34	all	all	DT
cord-315781-dejh8q22	182	35	M	M	NNP
cord-315781-dejh8q22	182	36	segments	segment	NNS
cord-315781-dejh8q22	182	37	of	of	IN
cord-315781-dejh8q22	182	38	pdm09	pdm09	CD
cord-315781-dejh8q22	182	39	.	.	.
cord-315781-dejh8q22	183	1	Such	such	JJ
cord-315781-dejh8q22	183	2	shifts	shift	NNS
cord-315781-dejh8q22	183	3	may	may	MD
cord-315781-dejh8q22	183	4	occur	occur	VB
cord-315781-dejh8q22	183	5	occasionally	occasionally	RB
cord-315781-dejh8q22	183	6	(	(	-LRB-
cord-315781-dejh8q22	183	7	Table	table	NN
cord-315781-dejh8q22	183	8	1	1	CD
cord-315781-dejh8q22	183	9	)	)	-RRB-
cord-315781-dejh8q22	183	10	.	.	.
cord-315781-dejh8q22	184	1	It	-PRON-	PRP
cord-315781-dejh8q22	184	2	should	should	MD
cord-315781-dejh8q22	184	3	be	be	VB
cord-315781-dejh8q22	184	4	noted	note	VBN
cord-315781-dejh8q22	184	5	that	that	IN
cord-315781-dejh8q22	184	6	assortment	assortment	NN
cord-315781-dejh8q22	184	7	of	of	IN
cord-315781-dejh8q22	184	8	the	the	DT
cord-315781-dejh8q22	184	9	M	M	NNP
cord-315781-dejh8q22	184	10	segments	segment	NNS
cord-315781-dejh8q22	184	11	was	be	VBD
cord-315781-dejh8q22	184	12	insufficient	insufficient	JJ
cord-315781-dejh8q22	184	13	to	to	TO
cord-315781-dejh8q22	184	14	produce	produce	VB
cord-315781-dejh8q22	184	15	the	the	DT
cord-315781-dejh8q22	184	16	pdm09	pdm09	CD
cord-315781-dejh8q22	184	17	virus	virus	NN
cord-315781-dejh8q22	184	18	.	.	.
cord-315781-dejh8q22	185	1	Although	although	IN
cord-315781-dejh8q22	185	2	the	the	DT
cord-315781-dejh8q22	185	3	reassortant	reassortant	JJ
cord-315781-dejh8q22	185	4	virus	virus	NN
cord-315781-dejh8q22	185	5	was	be	VBD
cord-315781-dejh8q22	185	6	repeatedly	repeatedly	RB
cord-315781-dejh8q22	185	7	detected	detect	VBN
cord-315781-dejh8q22	185	8	in	in	IN
cord-315781-dejh8q22	185	9	human	human	JJ
cord-315781-dejh8q22	185	10	samples	sample	NNS
cord-315781-dejh8q22	185	11	,	,	,
cord-315781-dejh8q22	185	12	it	-PRON-	PRP
cord-315781-dejh8q22	185	13	was	be	VBD
cord-315781-dejh8q22	185	14	transmitted	transmit	VBN
cord-315781-dejh8q22	185	15	from	from	IN
cord-315781-dejh8q22	185	16	swine	swine	NN
cord-315781-dejh8q22	185	17	and	and	CC
cord-315781-dejh8q22	185	18	did	do	VBD
cord-315781-dejh8q22	185	19	not	not	RB
cord-315781-dejh8q22	185	20	spread	spread	VB
cord-315781-dejh8q22	185	21	among	among	IN
cord-315781-dejh8q22	185	22	humans	human	NNS
cord-315781-dejh8q22	185	23	.	.	.
cord-315781-dejh8q22	186	1	The	the	DT
cord-315781-dejh8q22	186	2	segments	segment	NNS
cord-315781-dejh8q22	186	3	showed	show	VBD
cord-315781-dejh8q22	186	4	PCs	pc	NNS
cord-315781-dejh8q22	186	5	located	locate	VBN
cord-315781-dejh8q22	186	6	nearer	near	RBR
cord-315781-dejh8q22	186	7	the	the	DT
cord-315781-dejh8q22	186	8	average	average	NN
cord-315781-dejh8q22	186	9	compared	compare	VBN
cord-315781-dejh8q22	186	10	with	with	IN
cord-315781-dejh8q22	186	11	pdm09	pdm09	NNS
cord-315781-dejh8q22	186	12	(	(	-LRB-
cord-315781-dejh8q22	186	13	Figs	Figs	NNP
cord-315781-dejh8q22	186	14	.	.	.
cord-315781-dejh8q22	186	15	1C	1C	NNP
cord-315781-dejh8q22	186	16	and	and	CC
cord-315781-dejh8q22	186	17	S2	S2	NNP
cord-315781-dejh8q22	186	18	)	)	-RRB-
cord-315781-dejh8q22	186	19	.	.	.
cord-315781-dejh8q22	187	1	If	if	IN
cord-315781-dejh8q22	187	2	a	a	DT
cord-315781-dejh8q22	187	3	human	human	NN
cord-315781-dejh8q22	187	4	-	-	HYPH
cord-315781-dejh8q22	187	5	to	to	IN
cord-315781-dejh8q22	187	6	-	-	HYPH
cord-315781-dejh8q22	187	7	human	human	JJ
cord-315781-dejh8q22	187	8	transition	transition	NN
cord-315781-dejh8q22	187	9	requires	require	VBZ
cord-315781-dejh8q22	187	10	the	the	DT
cord-315781-dejh8q22	187	11	specific	specific	JJ
cord-315781-dejh8q22	187	12	characteristics	characteristic	NNS
cord-315781-dejh8q22	187	13	of	of	IN
cord-315781-dejh8q22	187	14	a	a	DT
cord-315781-dejh8q22	187	15	virus	virus	NN
cord-315781-dejh8q22	187	16	,	,	,
cord-315781-dejh8q22	187	17	those	those	DT
cord-315781-dejh8q22	187	18	characteristics	characteristic	NNS
cord-315781-dejh8q22	187	19	should	should	MD
cord-315781-dejh8q22	187	20	be	be	VB
cord-315781-dejh8q22	187	21	detected	detect	VBN
cord-315781-dejh8q22	187	22	in	in	IN
cord-315781-dejh8q22	187	23	some	some	DT
cord-315781-dejh8q22	187	24	of	of	IN
cord-315781-dejh8q22	187	25	the	the	DT
cord-315781-dejh8q22	187	26	PCs	pc	NNS
cord-315781-dejh8q22	187	27	when	when	WRB
cord-315781-dejh8q22	187	28	enough	enough	JJ
cord-315781-dejh8q22	187	29	samples	sample	NNS
cord-315781-dejh8q22	187	30	are	be	VBP
cord-315781-dejh8q22	187	31	included	include	VBN
cord-315781-dejh8q22	187	32	in	in	IN
cord-315781-dejh8q22	187	33	the	the	DT
cord-315781-dejh8q22	187	34	calculation	calculation	NN
cord-315781-dejh8q22	187	35	and	and	CC
cord-315781-dejh8q22	187	36	the	the	DT
cord-315781-dejh8q22	187	37	extreme	extreme	JJ
cord-315781-dejh8q22	187	38	values	value	NNS
cord-315781-dejh8q22	187	39	observed	observe	VBN
cord-315781-dejh8q22	187	40	in	in	IN
cord-315781-dejh8q22	187	41	PC1	PC1	NNP
cord-315781-dejh8q22	187	42	and	and	CC
cord-315781-dejh8q22	187	43	PC2	PC2	NNP
cord-315781-dejh8q22	187	44	may	may	MD
cord-315781-dejh8q22	187	45	reflect	reflect	VB
cord-315781-dejh8q22	187	46	such	such	JJ
cord-315781-dejh8q22	187	47	characteristics	characteristic	NNS
cord-315781-dejh8q22	187	48	.	.	.
cord-315781-dejh8q22	188	1	The	the	DT
cord-315781-dejh8q22	188	2	archiving	archiving	NN
cord-315781-dejh8q22	188	3	of	of	IN
cord-315781-dejh8q22	188	4	the	the	DT
cord-315781-dejh8q22	188	5	characteristics	characteristic	NNS
cord-315781-dejh8q22	188	6	requires	require	VBZ
cord-315781-dejh8q22	188	7	further	further	JJ
cord-315781-dejh8q22	188	8	shifts	shift	NNS
cord-315781-dejh8q22	188	9	in	in	IN
cord-315781-dejh8q22	188	10	all	all	PDT
cord-315781-dejh8q22	188	11	the	the	DT
cord-315781-dejh8q22	188	12	segments	segment	NNS
cord-315781-dejh8q22	188	13	of	of	IN
cord-315781-dejh8q22	188	14	the	the	DT
cord-315781-dejh8q22	188	15	assorted	assorted	JJ
cord-315781-dejh8q22	188	16	M	M	NNP
cord-315781-dejh8q22	188	17	virus	virus	NN
cord-315781-dejh8q22	188	18	.	.	.
cord-315781-dejh8q22	189	1	The	the	DT
cord-315781-dejh8q22	189	2	origin	origin	NN
cord-315781-dejh8q22	189	3	of	of	IN
cord-315781-dejh8q22	189	4	M	M	NNP
cord-315781-dejh8q22	189	5	type	type	NN
cord-315781-dejh8q22	189	6	polymerases	polymerase	NNS
cord-315781-dejh8q22	189	7	in	in	IN
cord-315781-dejh8q22	189	8	the	the	DT
cord-315781-dejh8q22	189	9	reassortant	reassortant	NN
cord-315781-dejh8q22	189	10	and	and	CC
cord-315781-dejh8q22	189	11	pdm09	pdm09	CD
cord-315781-dejh8q22	189	12	viruses	virus	NNS
cord-315781-dejh8q22	189	13	may	may	MD
cord-315781-dejh8q22	189	14	not	not	RB
cord-315781-dejh8q22	189	15	be	be	VB
cord-315781-dejh8q22	189	16	the	the	DT
cord-315781-dejh8q22	189	17	result	result	NN
cord-315781-dejh8q22	189	18	of	of	IN
cord-315781-dejh8q22	189	19	a	a	DT
cord-315781-dejh8q22	189	20	direct	direct	JJ
cord-315781-dejh8q22	189	21	shift	shift	NN
cord-315781-dejh8q22	189	22	from	from	IN
cord-315781-dejh8q22	189	23	avian	avian	JJ
cord-315781-dejh8q22	189	24	viruses	virus	NNS
cord-315781-dejh8q22	189	25	(	(	-LRB-
cord-315781-dejh8q22	189	26	Fig	Fig	NNP
cord-315781-dejh8q22	189	27	.	.	.
cord-315781-dejh8q22	189	28	S2	S2	NNP
cord-315781-dejh8q22	189	29	)	)	-RRB-
cord-315781-dejh8q22	189	30	.	.	.
cord-315781-dejh8q22	190	1	Instead	instead	RB
cord-315781-dejh8q22	190	2	,	,	,
cord-315781-dejh8q22	190	3	they	-PRON-	PRP
cord-315781-dejh8q22	190	4	might	may	MD
cord-315781-dejh8q22	190	5	be	be	VB
cord-315781-dejh8q22	190	6	maintained	maintain	VBN
cord-315781-dejh8q22	190	7	among	among	IN
cord-315781-dejh8q22	190	8	swine	swine	NN
cord-315781-dejh8q22	190	9	and	and	CC
cord-315781-dejh8q22	190	10	may	may	MD
cord-315781-dejh8q22	190	11	have	have	VB
cord-315781-dejh8q22	190	12	drifted	drift	VBN
cord-315781-dejh8q22	190	13	away	away	RB
cord-315781-dejh8q22	190	14	from	from	IN
cord-315781-dejh8q22	190	15	the	the	DT
cord-315781-dejh8q22	190	16	avian	avian	JJ
cord-315781-dejh8q22	190	17	type	type	NN
cord-315781-dejh8q22	191	1	(	(	-LRB-
cord-315781-dejh8q22	191	2	Fig	Fig	NNP
cord-315781-dejh8q22	191	3	.	.	NNP
cord-315781-dejh8q22	191	4	5	5	CD
cord-315781-dejh8q22	191	5	)	)	-RRB-
cord-315781-dejh8q22	191	6	.	.	.
cord-315781-dejh8q22	192	1	The	the	DT
cord-315781-dejh8q22	192	2	same	same	JJ
cord-315781-dejh8q22	192	3	would	would	MD
cord-315781-dejh8q22	192	4	be	be	VB
cord-315781-dejh8q22	192	5	true	true	JJ
cord-315781-dejh8q22	192	6	for	for	IN
cord-315781-dejh8q22	192	7	the	the	DT
cord-315781-dejh8q22	192	8	R	r	NN
cord-315781-dejh8q22	192	9	type	type	NN
cord-315781-dejh8q22	192	10	segments	segment	NNS
cord-315781-dejh8q22	192	11	.	.	.
cord-315781-dejh8q22	193	1	Although	although	IN
cord-315781-dejh8q22	193	2	most	most	JJS
cord-315781-dejh8q22	193	3	of	of	IN
cord-315781-dejh8q22	193	4	the	the	DT
cord-315781-dejh8q22	193	5	sequencing	sequencing	NN
cord-315781-dejh8q22	193	6	data	datum	NNS
cord-315781-dejh8q22	193	7	were	be	VBD
cord-315781-dejh8q22	193	8	obtained	obtain	VBN
cord-315781-dejh8q22	193	9	from	from	IN
cord-315781-dejh8q22	193	10	humans	human	NNS
cord-315781-dejh8q22	193	11	,	,	,
cord-315781-dejh8q22	193	12	the	the	DT
cord-315781-dejh8q22	193	13	R	r	NN
cord-315781-dejh8q22	193	14	type	type	NN
cord-315781-dejh8q22	193	15	may	may	MD
cord-315781-dejh8q22	193	16	have	have	VB
cord-315781-dejh8q22	193	17	been	be	VBN
cord-315781-dejh8q22	193	18	overlooked	overlook	VBN
cord-315781-dejh8q22	193	19	among	among	IN
cord-315781-dejh8q22	193	20	swine	swine	NN
cord-315781-dejh8q22	193	21	.	.	.
cord-315781-dejh8q22	194	1	If	if	IN
cord-315781-dejh8q22	194	2	these	these	DT
cord-315781-dejh8q22	194	3	viruses	virus	NNS
cord-315781-dejh8q22	194	4	do	do	VBP
cord-315781-dejh8q22	194	5	not	not	RB
cord-315781-dejh8q22	194	6	cause	cause	VB
cord-315781-dejh8q22	194	7	severe	severe	JJ
cord-315781-dejh8q22	194	8	symptoms	symptom	NNS
cord-315781-dejh8q22	194	9	,	,	,
cord-315781-dejh8q22	194	10	they	-PRON-	PRP
cord-315781-dejh8q22	194	11	may	may	MD
cord-315781-dejh8q22	194	12	not	not	RB
cord-315781-dejh8q22	194	13	attract	attract	VB
cord-315781-dejh8q22	194	14	the	the	DT
cord-315781-dejh8q22	194	15	attention	attention	NN
cord-315781-dejh8q22	194	16	of	of	IN
cord-315781-dejh8q22	194	17	farmers	farmer	NNS
cord-315781-dejh8q22	194	18	or	or	CC
cord-315781-dejh8q22	194	19	researchers	researcher	NNS
cord-315781-dejh8q22	194	20	.	.	.
cord-315781-dejh8q22	195	1	In	in	IN
cord-315781-dejh8q22	195	2	fact	fact	NN
cord-315781-dejh8q22	195	3	,	,	,
cord-315781-dejh8q22	195	4	focused	focus	VBN
cord-315781-dejh8q22	195	5	approaches	approach	NNS
cord-315781-dejh8q22	195	6	detected	detect	VBD
cord-315781-dejh8q22	195	7	the	the	DT
cord-315781-dejh8q22	195	8	R	r	NN
cord-315781-dejh8q22	195	9	type	type	NN
cord-315781-dejh8q22	195	10	in	in	IN
cord-315781-dejh8q22	195	11	swine	swine	NN
cord-315781-dejh8q22	195	12	(	(	-LRB-
cord-315781-dejh8q22	195	13	Fig	fig	NN
cord-315781-dejh8q22	195	14	.	.	.
cord-315781-dejh8q22	195	15	3B	3B	NNP
cord-315781-dejh8q22	195	16	)	)	-RRB-
cord-315781-dejh8q22	195	17	11	11	CD
cord-315781-dejh8q22	195	18	.	.	.
cord-315781-dejh8q22	196	1	Such	such	JJ
cord-315781-dejh8q22	196	2	endemic	endemic	JJ
cord-315781-dejh8q22	196	3	R	r	NN
cord-315781-dejh8q22	196	4	types	type	NNS
cord-315781-dejh8q22	196	5	may	may	MD
cord-315781-dejh8q22	196	6	show	show	VB
cord-315781-dejh8q22	196	7	lower	low	JJR
cord-315781-dejh8q22	196	8	values	value	NNS
cord-315781-dejh8q22	196	9	in	in	IN
cord-315781-dejh8q22	196	10	PC	pc	NN
cord-315781-dejh8q22	196	11	closer	close	RBR
cord-315781-dejh8q22	196	12	to	to	IN
cord-315781-dejh8q22	196	13	the	the	DT
cord-315781-dejh8q22	196	14	origin	origin	NN
cord-315781-dejh8q22	196	15	;	;	:
cord-315781-dejh8q22	196	16	e.g.	e.g.	RB
cord-315781-dejh8q22	196	17	,	,	,
cord-315781-dejh8q22	196	18	those	those	DT
cord-315781-dejh8q22	196	19	found	find	VBN
cord-315781-dejh8q22	196	20	in	in	IN
cord-315781-dejh8q22	196	21	England	England	NNP
cord-315781-dejh8q22	196	22	and	and	CC
cord-315781-dejh8q22	196	23	Dötlingen	Dötlingen	NNP
cord-315781-dejh8q22	196	24	in	in	IN
cord-315781-dejh8q22	196	25	2005	2005	CD
cord-315781-dejh8q22	196	26	might	may	MD
cord-315781-dejh8q22	196	27	satisfy	satisfy	VB
cord-315781-dejh8q22	196	28	this	this	DT
cord-315781-dejh8q22	196	29	condition	condition	NN
cord-315781-dejh8q22	196	30	(	(	-LRB-
cord-315781-dejh8q22	196	31	Fig	fig	NN
cord-315781-dejh8q22	196	32	.	.	.
cord-315781-dejh8q22	196	33	S2	s2	NN
cord-315781-dejh8q22	196	34	;	;	:
cord-315781-dejh8q22	196	35	HA	HA	NNP
cord-315781-dejh8q22	196	36	)	)	-RRB-
cord-315781-dejh8q22	196	37	,	,	,
cord-315781-dejh8q22	196	38	and	and	CC
cord-315781-dejh8q22	196	39	other	other	JJ
cord-315781-dejh8q22	196	40	segments	segment	NNS
cord-315781-dejh8q22	196	41	also	also	RB
cord-315781-dejh8q22	196	42	exhibited	exhibit	VBD
cord-315781-dejh8q22	196	43	such	such	JJ
cord-315781-dejh8q22	196	44	endemic	endemic	JJ
cord-315781-dejh8q22	196	45	candidates	candidate	NNS
cord-315781-dejh8q22	196	46	.	.	.
cord-315781-dejh8q22	197	1	Unfortunately	unfortunately	RB
cord-315781-dejh8q22	197	2	,	,	,
cord-315781-dejh8q22	197	3	it	-PRON-	PRP
cord-315781-dejh8q22	197	4	is	be	VBZ
cord-315781-dejh8q22	197	5	difficult	difficult	JJ
cord-315781-dejh8q22	197	6	to	to	TO
cord-315781-dejh8q22	197	7	estimate	estimate	VB
cord-315781-dejh8q22	197	8	the	the	DT
cord-315781-dejh8q22	197	9	history	history	NN
cord-315781-dejh8q22	197	10	of	of	IN
cord-315781-dejh8q22	197	11	old	old	JJ
cord-315781-dejh8q22	197	12	viruses	virus	NNS
cord-315781-dejh8q22	197	13	because	because	IN
cord-315781-dejh8q22	197	14	of	of	IN
cord-315781-dejh8q22	197	15	the	the	DT
cord-315781-dejh8q22	197	16	shortage	shortage	NN
cord-315781-dejh8q22	197	17	of	of	IN
cord-315781-dejh8q22	197	18	data	datum	NNS
cord-315781-dejh8q22	197	19	.	.	.
cord-315781-dejh8q22	198	1	Some	some	DT
cord-315781-dejh8q22	198	2	of	of	IN
cord-315781-dejh8q22	198	3	the	the	DT
cord-315781-dejh8q22	198	4	segments	segment	NNS
cord-315781-dejh8q22	198	5	of	of	IN
cord-315781-dejh8q22	198	6	the	the	DT
cord-315781-dejh8q22	198	7	1930	1930	CD
cord-315781-dejh8q22	198	8	strain	strain	NN
cord-315781-dejh8q22	198	9	exhibited	exhibit	VBD
cord-315781-dejh8q22	198	10	interesting	interesting	JJ
cord-315781-dejh8q22	198	11	positions	position	NNS
cord-315781-dejh8q22	198	12	on	on	IN
cord-315781-dejh8q22	198	13	the	the	DT
cord-315781-dejh8q22	198	14	branches	branch	NNS
cord-315781-dejh8q22	198	15	:	:	:
cord-315781-dejh8q22	198	16	i.e.	i.e.	FW
cord-315781-dejh8q22	198	17	,	,	,
cord-315781-dejh8q22	198	18	some	some	DT
cord-315781-dejh8q22	198	19	were	be	VBD
cord-315781-dejh8q22	198	20	R	r	NN
cord-315781-dejh8q22	198	21	type	type	NN
cord-315781-dejh8q22	198	22	,	,	,
cord-315781-dejh8q22	198	23	while	while	IN
cord-315781-dejh8q22	198	24	others	other	NNS
cord-315781-dejh8q22	198	25	were	be	VBD
cord-315781-dejh8q22	198	26	located	locate	VBN
cord-315781-dejh8q22	198	27	between	between	IN
cord-315781-dejh8q22	198	28	the	the	DT
cord-315781-dejh8q22	198	29	R	r	NN
cord-315781-dejh8q22	198	30	and	and	CC
cord-315781-dejh8q22	198	31	(	(	-LRB-
cord-315781-dejh8q22	198	32	M	M	NNP
cord-315781-dejh8q22	198	33	or	or	CC
cord-315781-dejh8q22	198	34	U	U	NNP
cord-315781-dejh8q22	198	35	)	)	-RRB-
cord-315781-dejh8q22	198	36	types	type	NNS
cord-315781-dejh8q22	198	37	(	(	-LRB-
cord-315781-dejh8q22	198	38	Fig	Fig	NNP
cord-315781-dejh8q22	198	39	.	.	.
cord-315781-dejh8q22	198	40	S2	S2	NNP
cord-315781-dejh8q22	198	41	)	)	-RRB-
cord-315781-dejh8q22	198	42	.	.	.
cord-315781-dejh8q22	199	1	The	the	DT
cord-315781-dejh8q22	199	2	segments	segment	NNS
cord-315781-dejh8q22	199	3	would	would	MD
cord-315781-dejh8q22	199	4	be	be	VB
cord-315781-dejh8q22	199	5	those	those	DT
cord-315781-dejh8q22	199	6	close	close	JJ
cord-315781-dejh8q22	199	7	to	to	IN
cord-315781-dejh8q22	199	8	the	the	DT
cord-315781-dejh8q22	199	9	branching	branch	VBG
cord-315781-dejh8q22	199	10	point	point	NN
cord-315781-dejh8q22	199	11	of	of	IN
cord-315781-dejh8q22	199	12	the	the	DT
cord-315781-dejh8q22	199	13	groups	group	NNS
cord-315781-dejh8q22	199	14	.	.	.
cord-315781-dejh8q22	200	1	However	however	RB
cord-315781-dejh8q22	200	2	,	,	,
cord-315781-dejh8q22	200	3	this	this	DT
cord-315781-dejh8q22	200	4	does	do	VBZ
cord-315781-dejh8q22	200	5	not	not	RB
cord-315781-dejh8q22	200	6	necessarily	necessarily	RB
cord-315781-dejh8q22	200	7	mean	mean	VB
cord-315781-dejh8q22	200	8	that	that	IN
cord-315781-dejh8q22	200	9	the	the	DT
cord-315781-dejh8q22	200	10	branching	branching	NN
cord-315781-dejh8q22	200	11	occurred	occur	VBD
cord-315781-dejh8q22	200	12	recently	recently	RB
cord-315781-dejh8q22	200	13	;	;	:
cord-315781-dejh8q22	200	14	i.e.	i.e.	FW
cord-315781-dejh8q22	200	15	,	,	,
cord-315781-dejh8q22	200	16	it	-PRON-	PRP
cord-315781-dejh8q22	200	17	could	could	MD
cord-315781-dejh8q22	200	18	have	have	VB
cord-315781-dejh8q22	200	19	been	be	VBN
cord-315781-dejh8q22	200	20	preserved	preserve	VBN
cord-315781-dejh8q22	200	21	among	among	IN
cord-315781-dejh8q22	200	22	swine	swine	NN
cord-315781-dejh8q22	200	23	at	at	IN
cord-315781-dejh8q22	200	24	least	least	JJS
cord-315781-dejh8q22	200	25	until	until	IN
cord-315781-dejh8q22	200	26	1930	1930	CD
cord-315781-dejh8q22	200	27	.	.	.
cord-315781-dejh8q22	201	1	Whether	whether	IN
cord-315781-dejh8q22	201	2	the	the	DT
cord-315781-dejh8q22	201	3	1918	1918	CD
cord-315781-dejh8q22	201	4	and/or	and/or	CC
cord-315781-dejh8q22	201	5	1943	1943	CD
cord-315781-dejh8q22	201	6	human	human	JJ
cord-315781-dejh8q22	201	7	strains	strain	NNS
cord-315781-dejh8q22	201	8	are	be	VBP
cord-315781-dejh8q22	201	9	lineal	lineal	JJ
cord-315781-dejh8q22	201	10	ancestors	ancestor	NNS
cord-315781-dejh8q22	201	11	of	of	IN
cord-315781-dejh8q22	201	12	the	the	DT
cord-315781-dejh8q22	201	13	1977	1977	CD
cord-315781-dejh8q22	201	14	pandemic	pandemic	NN
cord-315781-dejh8q22	201	15	virus	virus	NN
cord-315781-dejh8q22	201	16	remains	remain	VBZ
cord-315781-dejh8q22	201	17	uncertain	uncertain	JJ
cord-315781-dejh8q22	201	18	.	.	.
cord-315781-dejh8q22	202	1	It	-PRON-	PRP
cord-315781-dejh8q22	202	2	should	should	MD
cord-315781-dejh8q22	202	3	be	be	VB
cord-315781-dejh8q22	202	4	noted	note	VBN
cord-315781-dejh8q22	202	5	that	that	IN
cord-315781-dejh8q22	202	6	these	these	DT
cord-315781-dejh8q22	202	7	viruses	virus	NNS
cord-315781-dejh8q22	202	8	were	be	VBD
cord-315781-dejh8q22	202	9	included	include	VBN
cord-315781-dejh8q22	202	10	in	in	IN
cord-315781-dejh8q22	202	11	different	different	JJ
cord-315781-dejh8q22	202	12	epidemic	epidemic	NN
cord-315781-dejh8q22	202	13	series	series	NN
cord-315781-dejh8q22	202	14	on	on	IN
cord-315781-dejh8q22	202	15	different	different	JJ
cord-315781-dejh8q22	202	16	memories	memory	NNS
cord-315781-dejh8q22	202	17	of	of	IN
cord-315781-dejh8q22	202	18	immunity	immunity	NN
cord-315781-dejh8q22	202	19	among	among	IN
cord-315781-dejh8q22	202	20	humans	human	NNS
cord-315781-dejh8q22	202	21	.	.	.
cord-315781-dejh8q22	203	1	These	these	DT
cord-315781-dejh8q22	203	2	immune	immune	JJ
cord-315781-dejh8q22	203	3	memories	memory	NNS
cord-315781-dejh8q22	203	4	are	be	VBP
cord-315781-dejh8q22	203	5	changing	change	VBG
cord-315781-dejh8q22	203	6	because	because	IN
cord-315781-dejh8q22	203	7	of	of	IN
cord-315781-dejh8q22	203	8	the	the	DT
cord-315781-dejh8q22	203	9	change	change	NN
cord-315781-dejh8q22	203	10	of	of	IN
cord-315781-dejh8q22	203	11	human	human	JJ
cord-315781-dejh8q22	203	12	generations	generation	NNS
cord-315781-dejh8q22	203	13	,	,	,
cord-315781-dejh8q22	203	14	i.e.	i.e.	FW
cord-315781-dejh8q22	203	15	,	,	,
cord-315781-dejh8q22	203	16	the	the	DT
cord-315781-dejh8q22	203	17	return	return	NN
cord-315781-dejh8q22	203	18	of	of	IN
cord-315781-dejh8q22	203	19	the	the	DT
cord-315781-dejh8q22	203	20	R	r	NN
cord-315781-dejh8q22	203	21	group	group	NN
cord-315781-dejh8q22	203	22	observed	observe	VBD
cord-315781-dejh8q22	203	23	over	over	IN
cord-315781-dejh8q22	203	24	recent	recent	JJ
cord-315781-dejh8q22	203	25	years	year	NNS
cord-315781-dejh8q22	203	26	(	(	-LRB-
cord-315781-dejh8q22	203	27	Fig	Fig	NNP
cord-315781-dejh8q22	203	28	.	.	.
cord-315781-dejh8q22	203	29	2C	2C	NNP
cord-315781-dejh8q22	203	30	,	,	,
cord-315781-dejh8q22	203	31	grey	grey	NNP
cord-315781-dejh8q22	203	32	)	)	-RRB-
cord-315781-dejh8q22	203	33	might	may	MD
cord-315781-dejh8q22	203	34	have	have	VB
cord-315781-dejh8q22	203	35	been	be	VBN
cord-315781-dejh8q22	203	36	enabled	enable	VBN
cord-315781-dejh8q22	203	37	by	by	IN
cord-315781-dejh8q22	203	38	such	such	JJ
cord-315781-dejh8q22	203	39	changes	change	NNS
cord-315781-dejh8q22	203	40	.	.	.
cord-315781-dejh8q22	204	1	Estimation	estimation	NN
cord-315781-dejh8q22	204	2	of	of	IN
cord-315781-dejh8q22	204	3	future	future	JJ
cord-315781-dejh8q22	204	4	viruses	virus	NNS
cord-315781-dejh8q22	204	5	and	and	CC
cord-315781-dejh8q22	204	6	vaccination	vaccination	NN
cord-315781-dejh8q22	204	7	:	:	:
cord-315781-dejh8q22	204	8	patterns	pattern	NNS
cord-315781-dejh8q22	204	9	of	of	IN
cord-315781-dejh8q22	204	10	change	change	NN
cord-315781-dejh8q22	204	11	were	be	VBD
cord-315781-dejh8q22	204	12	observed	observe	VBN
cord-315781-dejh8q22	204	13	for	for	IN
cord-315781-dejh8q22	204	14	the	the	DT
cord-315781-dejh8q22	204	15	human	human	JJ
cord-315781-dejh8q22	204	16	R	r	NN
cord-315781-dejh8q22	204	17	and	and	CC
cord-315781-dejh8q22	204	18	M	M	NNP
cord-315781-dejh8q22	204	19	types	type	NNS
cord-315781-dejh8q22	204	20	in	in	IN
cord-315781-dejh8q22	204	21	each	each	DT
cord-315781-dejh8q22	204	22	of	of	IN
cord-315781-dejh8q22	204	23	the	the	DT
cord-315781-dejh8q22	204	24	PC	pc	NN
cord-315781-dejh8q22	204	25	axes	axis	NNS
cord-315781-dejh8q22	204	26	(	(	-LRB-
cord-315781-dejh8q22	204	27	Figs	fig	NNS
cord-315781-dejh8q22	204	28	.	.	.
cord-315781-dejh8q22	205	1	2A	2A	NNP
cord-315781-dejh8q22	205	2	,	,	,
cord-315781-dejh8q22	205	3	B	B	NNP
cord-315781-dejh8q22	205	4	,	,	,
cord-315781-dejh8q22	205	5	3A	3A	NNP
cord-315781-dejh8q22	205	6	,	,	,
cord-315781-dejh8q22	205	7	and	and	CC
cord-315781-dejh8q22	205	8	S4A	S4A	NNP
cord-315781-dejh8q22	205	9	)	)	-RRB-
cord-315781-dejh8q22	205	10	.	.	.
cord-315781-dejh8q22	206	1	Although	although	IN
cord-315781-dejh8q22	206	2	PCA	PCA	NNP
cord-315781-dejh8q22	206	3	produces	produce	VBZ
cord-315781-dejh8q22	206	4	sin	sin	NN
cord-315781-dejh8q22	206	5	curves	curve	NNS
cord-315781-dejh8q22	206	6	for	for	IN
cord-315781-dejh8q22	206	7	the	the	DT
cord-315781-dejh8q22	206	8	records	record	NNS
cord-315781-dejh8q22	206	9	of	of	IN
cord-315781-dejh8q22	206	10	random	random	JJ
cord-315781-dejh8q22	206	11	walk	walk	NN
cord-315781-dejh8q22	206	12	mutations	mutation	NNS
cord-315781-dejh8q22	206	13	6	6	CD
cord-315781-dejh8q22	206	14	,	,	,
cord-315781-dejh8q22	206	15	the	the	DT
cord-315781-dejh8q22	206	16	real	real	JJ
cord-315781-dejh8q22	206	17	patterns	pattern	NNS
cord-315781-dejh8q22	206	18	may	may	MD
cord-315781-dejh8q22	206	19	reflect	reflect	VB
cord-315781-dejh8q22	206	20	some	some	DT
cord-315781-dejh8q22	206	21	rules	rule	NNS
cord-315781-dejh8q22	206	22	in	in	IN
cord-315781-dejh8q22	206	23	the	the	DT
cord-315781-dejh8q22	206	24	drift	drift	NN
cord-315781-dejh8q22	206	25	of	of	IN
cord-315781-dejh8q22	206	26	genomes	genome	NNS
cord-315781-dejh8q22	206	27	.	.	.
cord-315781-dejh8q22	207	1	As	as	IN
cord-315781-dejh8q22	207	2	patterns	pattern	NNS
cord-315781-dejh8q22	207	3	of	of	IN
cord-315781-dejh8q22	207	4	M	M	NNP
cord-315781-dejh8q22	207	5	groups	group	NNS
cord-315781-dejh8q22	207	6	become	become	VBP
cord-315781-dejh8q22	207	7	apparent	apparent	JJ
cord-315781-dejh8q22	207	8	,	,	,
cord-315781-dejh8q22	207	9	we	-PRON-	PRP
cord-315781-dejh8q22	207	10	can	can	MD
cord-315781-dejh8q22	207	11	compare	compare	VB
cord-315781-dejh8q22	207	12	them	-PRON-	PRP
cord-315781-dejh8q22	207	13	between	between	IN
cord-315781-dejh8q22	207	14	M	M	NNP
cord-315781-dejh8q22	207	15	and	and	CC
cord-315781-dejh8q22	207	16	R	r	NN
cord-315781-dejh8q22	207	17	viruses	virus	NNS
cord-315781-dejh8q22	207	18	to	to	TO
cord-315781-dejh8q22	207	19	estimate	estimate	VB
cord-315781-dejh8q22	207	20	the	the	DT
cord-315781-dejh8q22	207	21	hidden	hide	VBN
cord-315781-dejh8q22	207	22	rules	rule	NNS
cord-315781-dejh8q22	207	23	.	.	.
cord-315781-dejh8q22	208	1	Although	although	IN
cord-315781-dejh8q22	208	2	HA	HA	NNP
cord-315781-dejh8q22	208	3	is	be	VBZ
cord-315781-dejh8q22	208	4	thought	think	VBN
cord-315781-dejh8q22	208	5	to	to	TO
cord-315781-dejh8q22	208	6	be	be	VB
cord-315781-dejh8q22	208	7	the	the	DT
cord-315781-dejh8q22	208	8	primary	primary	JJ
cord-315781-dejh8q22	208	9	target	target	NN
cord-315781-dejh8q22	208	10	of	of	IN
cord-315781-dejh8q22	208	11	the	the	DT
cord-315781-dejh8q22	208	12	human	human	JJ
cord-315781-dejh8q22	208	13	adaptive	adaptive	JJ
cord-315781-dejh8q22	208	14	immune	immune	JJ
cord-315781-dejh8q22	208	15	response	response	NN
cord-315781-dejh8q22	208	16	1	1	CD
cord-315781-dejh8q22	208	17	,	,	,
cord-315781-dejh8q22	208	18	other	other	JJ
cord-315781-dejh8q22	208	19	segments	segment	NNS
cord-315781-dejh8q22	208	20	that	that	WDT
cord-315781-dejh8q22	208	21	include	include	VBP
cord-315781-dejh8q22	208	22	proteins	protein	NNS
cord-315781-dejh8q22	208	23	located	locate	VBN
cord-315781-dejh8q22	208	24	inside	inside	IN
cord-315781-dejh8q22	208	25	the	the	DT
cord-315781-dejh8q22	208	26	virus	virus	NN
cord-315781-dejh8q22	208	27	particle	particle	NN
cord-315781-dejh8q22	208	28	also	also	RB
cord-315781-dejh8q22	208	29	drifted	drift	VBD
cord-315781-dejh8q22	208	30	with	with	IN
cord-315781-dejh8q22	208	31	a	a	DT
cord-315781-dejh8q22	208	32	magnitude	magnitude	NN
cord-315781-dejh8q22	208	33	similar	similar	JJ
cord-315781-dejh8q22	208	34	to	to	IN
cord-315781-dejh8q22	208	35	that	that	DT
cord-315781-dejh8q22	208	36	of	of	IN
cord-315781-dejh8q22	208	37	HA	HA	NNP
cord-315781-dejh8q22	208	38	,	,	,
cord-315781-dejh8q22	208	39	which	which	WDT
cord-315781-dejh8q22	208	40	suggests	suggest	VBZ
cord-315781-dejh8q22	208	41	a	a	DT
cord-315781-dejh8q22	208	42	common	common	JJ
cord-315781-dejh8q22	208	43	mutation	mutation	NN
cord-315781-dejh8q22	208	44	frequency	frequency	NN
cord-315781-dejh8q22	208	45	(	(	-LRB-
cord-315781-dejh8q22	208	46	Fig	Fig	NNP
cord-315781-dejh8q22	208	47	.	.	.
cord-315781-dejh8q22	208	48	S4C	s4c	NN
cord-315781-dejh8q22	208	49	)	)	-RRB-
cord-315781-dejh8q22	208	50	.	.	.
cord-315781-dejh8q22	209	1	This	this	DT
cord-315781-dejh8q22	209	2	observation	observation	NN
cord-315781-dejh8q22	209	3	was	be	VBD
cord-315781-dejh8q22	209	4	unexpected	unexpected	JJ
cord-315781-dejh8q22	209	5	because	because	IN
cord-315781-dejh8q22	209	6	mutations	mutation	NNS
cord-315781-dejh8q22	209	7	may	may	MD
cord-315781-dejh8q22	209	8	lead	lead	VB
cord-315781-dejh8q22	209	9	to	to	IN
cord-315781-dejh8q22	209	10	malfunction	malfunction	NN
cord-315781-dejh8q22	209	11	;	;	:
cord-315781-dejh8q22	209	12	if	if	IN
cord-315781-dejh8q22	209	13	they	-PRON-	PRP
cord-315781-dejh8q22	209	14	are	be	VBP
cord-315781-dejh8q22	209	15	not	not	RB
cord-315781-dejh8q22	209	16	the	the	DT
cord-315781-dejh8q22	209	17	target	target	NN
cord-315781-dejh8q22	209	18	of	of	IN
cord-315781-dejh8q22	209	19	immunity	immunity	NN
cord-315781-dejh8q22	209	20	,	,	,
cord-315781-dejh8q22	209	21	they	-PRON-	PRP
cord-315781-dejh8q22	209	22	should	should	MD
cord-315781-dejh8q22	209	23	be	be	VB
cord-315781-dejh8q22	209	24	conserved	conserve	VBN
cord-315781-dejh8q22	209	25	,	,	,
cord-315781-dejh8q22	209	26	similar	similar	JJ
cord-315781-dejh8q22	209	27	to	to	IN
cord-315781-dejh8q22	209	28	those	those	DT
cord-315781-dejh8q22	209	29	of	of	IN
cord-315781-dejh8q22	209	30	livestock	livestock	NN
cord-315781-dejh8q22	209	31	viruses	virus	NNS
cord-315781-dejh8q22	209	32	.	.	.
cord-315781-dejh8q22	210	1	As	as	IN
cord-315781-dejh8q22	210	2	the	the	DT
cord-315781-dejh8q22	210	3	segments	segment	NNS
cord-315781-dejh8q22	210	4	are	be	VBP
cord-315781-dejh8q22	210	5	displayed	display	VBN
cord-315781-dejh8q22	210	6	on	on	IN
cord-315781-dejh8q22	210	7	the	the	DT
cord-315781-dejh8q22	210	8	surface	surface	NN
cord-315781-dejh8q22	210	9	of	of	IN
cord-315781-dejh8q22	210	10	infected	infected	JJ
cord-315781-dejh8q22	210	11	cells	cell	NNS
cord-315781-dejh8q22	210	12	,	,	,
cord-315781-dejh8q22	210	13	they	-PRON-	PRP
cord-315781-dejh8q22	210	14	will	will	MD
cord-315781-dejh8q22	210	15	activate	activate	VB
cord-315781-dejh8q22	210	16	specific	specific	JJ
cord-315781-dejh8q22	210	17	immune	immune	JJ
cord-315781-dejh8q22	210	18	cells	cell	NNS
cord-315781-dejh8q22	210	19	,	,	,
cord-315781-dejh8q22	210	20	which	which	WDT
cord-315781-dejh8q22	210	21	may	may	MD
cord-315781-dejh8q22	210	22	play	play	VB
cord-315781-dejh8q22	210	23	important	important	JJ
cord-315781-dejh8q22	210	24	roles	role	NNS
cord-315781-dejh8q22	210	25	in	in	IN
cord-315781-dejh8q22	210	26	the	the	DT
cord-315781-dejh8q22	210	27	human	human	JJ
cord-315781-dejh8q22	210	28	immune	immune	NN
cord-315781-dejh8q22	210	29	system	system	NN
cord-315781-dejh8q22	210	30	.	.	.
cord-315781-dejh8q22	211	1	It	-PRON-	PRP
cord-315781-dejh8q22	211	2	is	be	VBZ
cord-315781-dejh8q22	211	3	obvious	obvious	JJ
cord-315781-dejh8q22	211	4	that	that	IN
cord-315781-dejh8q22	211	5	any	any	DT
cord-315781-dejh8q22	211	6	strain	strain	NN
cord-315781-dejh8q22	211	7	that	that	WDT
cord-315781-dejh8q22	211	8	has	have	VBZ
cord-315781-dejh8q22	211	9	caused	cause	VBN
cord-315781-dejh8q22	211	10	an	an	DT
cord-315781-dejh8q22	211	11	outbreak	outbreak	NN
cord-315781-dejh8q22	211	12	will	will	MD
cord-315781-dejh8q22	211	13	not	not	RB
cord-315781-dejh8q22	211	14	appear	appear	VB
cord-315781-dejh8q22	211	15	again	again	RB
cord-315781-dejh8q22	211	16	for	for	IN
cord-315781-dejh8q22	211	17	decades	decade	NNS
cord-315781-dejh8q22	211	18	among	among	IN
cord-315781-dejh8q22	211	19	humans	human	NNS
cord-315781-dejh8q22	211	20	.	.	.
cord-315781-dejh8q22	212	1	In	in	IN
cord-315781-dejh8q22	212	2	contrast	contrast	NN
cord-315781-dejh8q22	212	3	to	to	IN
cord-315781-dejh8q22	212	4	the	the	DT
cord-315781-dejh8q22	212	5	case	case	NN
cord-315781-dejh8q22	212	6	of	of	IN
cord-315781-dejh8q22	212	7	the	the	DT
cord-315781-dejh8q22	212	8	H3N2	H3N2	NNP
cord-315781-dejh8q22	212	9	viruses	virus	NNS
cord-315781-dejh8q22	212	10	,	,	,
cord-315781-dejh8q22	212	11	H1N1	H1N1	NNP
cord-315781-dejh8q22	212	12	outbreaks	outbreak	NNS
cord-315781-dejh8q22	212	13	rarely	rarely	RB
cord-315781-dejh8q22	212	14	occur	occur	VBP
cord-315781-dejh8q22	212	15	in	in	IN
cord-315781-dejh8q22	212	16	two	two	CD
cord-315781-dejh8q22	212	17	consecutive	consecutive	JJ
cord-315781-dejh8q22	212	18	seasons	season	NNS
cord-315781-dejh8q22	212	19	(	(	-LRB-
cord-315781-dejh8q22	212	20	Figs	fig	NNS
cord-315781-dejh8q22	212	21	.	.	.
cord-315781-dejh8q22	213	1	2D	2D	NNP
cord-315781-dejh8q22	213	2	and	and	CC
cord-315781-dejh8q22	213	3	 	 	_SP
cord-315781-dejh8q22	213	4	S5	S5	NNP
cord-315781-dejh8q22	213	5	)	)	-RRB-
cord-315781-dejh8q22	213	6	.	.	.
cord-315781-dejh8q22	214	1	This	this	DT
cord-315781-dejh8q22	214	2	shows	show	VBZ
cord-315781-dejh8q22	214	3	that	that	IN
cord-315781-dejh8q22	214	4	most	most	JJS
cord-315781-dejh8q22	214	5	people	people	NNS
cord-315781-dejh8q22	214	6	exposed	expose	VBN
cord-315781-dejh8q22	214	7	to	to	IN
cord-315781-dejh8q22	214	8	the	the	DT
cord-315781-dejh8q22	214	9	virus	virus	NN
cord-315781-dejh8q22	214	10	are	be	VBP
cord-315781-dejh8q22	214	11	infected	infect	VBN
cord-315781-dejh8q22	214	12	asymptomatically	asymptomatically	RB
cord-315781-dejh8q22	214	13	during	during	IN
cord-315781-dejh8q22	214	14	the	the	DT
cord-315781-dejh8q22	214	15	viral	viral	JJ
cord-315781-dejh8q22	214	16	outbreak	outbreak	NN
cord-315781-dejh8q22	214	17	and	and	CC
cord-315781-dejh8q22	214	18	become	become	VB
cord-315781-dejh8q22	214	19	immune	immune	JJ
cord-315781-dejh8q22	214	20	;	;	:
cord-315781-dejh8q22	214	21	otherwise	otherwise	RB
cord-315781-dejh8q22	214	22	,	,	,
cord-315781-dejh8q22	214	23	the	the	DT
cord-315781-dejh8q22	214	24	virus	virus	NN
cord-315781-dejh8q22	214	25	could	could	MD
cord-315781-dejh8q22	214	26	infect	infect	VB
cord-315781-dejh8q22	214	27	a	a	DT
cord-315781-dejh8q22	214	28	portion	portion	NN
cord-315781-dejh8q22	214	29	of	of	IN
cord-315781-dejh8q22	214	30	receptive	receptive	JJ
cord-315781-dejh8q22	214	31	people	people	NNS
cord-315781-dejh8q22	214	32	that	that	WDT
cord-315781-dejh8q22	214	33	were	be	VBD
cord-315781-dejh8q22	214	34	not	not	RB
cord-315781-dejh8q22	214	35	infected	infect	VBN
cord-315781-dejh8q22	214	36	in	in	IN
cord-315781-dejh8q22	214	37	the	the	DT
cord-315781-dejh8q22	214	38	previous	previous	JJ
cord-315781-dejh8q22	214	39	year	year	NN
cord-315781-dejh8q22	214	40	.	.	.
cord-315781-dejh8q22	215	1	Also	also	RB
cord-315781-dejh8q22	215	2	,	,	,
cord-315781-dejh8q22	215	3	the	the	DT
cord-315781-dejh8q22	215	4	drift	drift	NN
cord-315781-dejh8q22	215	5	occurring	occur	VBG
cord-315781-dejh8q22	215	6	in	in	IN
cord-315781-dejh8q22	215	7	a	a	DT
cord-315781-dejh8q22	215	8	single	single	JJ
cord-315781-dejh8q22	215	9	year	year	NN
cord-315781-dejh8q22	215	10	is	be	VBZ
cord-315781-dejh8q22	215	11	insufficient	insufficient	JJ
cord-315781-dejh8q22	215	12	for	for	IN
cord-315781-dejh8q22	215	13	escaping	escape	VBG
cord-315781-dejh8q22	215	14	the	the	DT
cord-315781-dejh8q22	215	15	immune	immune	JJ
cord-315781-dejh8q22	215	16	system	system	NN
cord-315781-dejh8q22	215	17	.	.	.
cord-315781-dejh8q22	216	1	The	the	DT
cord-315781-dejh8q22	216	2	pdm09	pdm09	NNP
cord-315781-dejh8q22	216	3	virus	virus	NN
cord-315781-dejh8q22	216	4	appeared	appear	VBD
cord-315781-dejh8q22	216	5	after	after	IN
cord-315781-dejh8q22	216	6	the	the	DT
cord-315781-dejh8q22	216	7	flu	flu	NN
cord-315781-dejh8q22	216	8	season	season	NN
cord-315781-dejh8q22	216	9	and	and	CC
cord-315781-dejh8q22	216	10	spread	spread	VB
cord-315781-dejh8q22	216	11	worldwide	worldwide	RB
cord-315781-dejh8q22	216	12	from	from	IN
cord-315781-dejh8q22	216	13	April	April	NNP
cord-315781-dejh8q22	216	14	2009	2009	CD
cord-315781-dejh8q22	216	15	to	to	IN
cord-315781-dejh8q22	216	16	March	March	NNP
cord-315781-dejh8q22	216	17	2010	2010	CD
cord-315781-dejh8q22	216	18	(	(	-LRB-
cord-315781-dejh8q22	216	19	Fig	Fig	NNP
cord-315781-dejh8q22	216	20	.	.	.
cord-315781-dejh8q22	216	21	S5	S5	NNP
cord-315781-dejh8q22	216	22	)	)	-RRB-
cord-315781-dejh8q22	216	23	.	.	.
cord-315781-dejh8q22	217	1	The	the	DT
cord-315781-dejh8q22	217	2	extraordinary	extraordinary	JJ
cord-315781-dejh8q22	217	3	infectivity	infectivity	NN
cord-315781-dejh8q22	217	4	of	of	IN
cord-315781-dejh8q22	217	5	this	this	DT
cord-315781-dejh8q22	217	6	virus	virus	NN
cord-315781-dejh8q22	217	7	may	may	MD
cord-315781-dejh8q22	217	8	have	have	VB
cord-315781-dejh8q22	217	9	been	be	VBN
cord-315781-dejh8q22	217	10	caused	cause	VBN
cord-315781-dejh8q22	217	11	by	by	IN
cord-315781-dejh8q22	217	12	epitopes	epitope	NNS
cord-315781-dejh8q22	217	13	that	that	WDT
cord-315781-dejh8q22	217	14	were	be	VBD
cord-315781-dejh8q22	217	15	new	new	JJ
cord-315781-dejh8q22	217	16	to	to	IN
cord-315781-dejh8q22	217	17	humans	human	NNS
cord-315781-dejh8q22	217	18	.	.	.
cord-315781-dejh8q22	218	1	Therefore	therefore	RB
cord-315781-dejh8q22	218	2	,	,	,
cord-315781-dejh8q22	218	3	the	the	DT
cord-315781-dejh8q22	218	4	present	present	JJ
cord-315781-dejh8q22	218	5	system	system	NN
cord-315781-dejh8q22	218	6	of	of	IN
cord-315781-dejh8q22	218	7	vaccine	vaccine	NN
cord-315781-dejh8q22	218	8	production	production	NN
cord-315781-dejh8q22	218	9	to	to	TO
cord-315781-dejh8q22	218	10	control	control	VB
cord-315781-dejh8q22	218	11	influenza	influenza	NN
cord-315781-dejh8q22	218	12	infections	infection	NNS
cord-315781-dejh8q22	218	13	,	,	,
cord-315781-dejh8q22	218	14	which	which	WDT
cord-315781-dejh8q22	218	15	uses	use	VBZ
cord-315781-dejh8q22	218	16	eggs	egg	NNS
cord-315781-dejh8q22	218	17	,	,	,
cord-315781-dejh8q22	218	18	has	have	VBZ
cord-315781-dejh8q22	218	19	a	a	DT
cord-315781-dejh8q22	218	20	critical	critical	JJ
cord-315781-dejh8q22	218	21	defect	defect	NN
cord-315781-dejh8q22	218	22	:	:	:
cord-315781-dejh8q22	218	23	i.e.	i.e.	FW
cord-315781-dejh8q22	218	24	,	,	,
cord-315781-dejh8q22	218	25	none	none	NN
cord-315781-dejh8q22	218	26	of	of	IN
cord-315781-dejh8q22	218	27	the	the	DT
cord-315781-dejh8q22	218	28	stock	stock	NN
cord-315781-dejh8q22	218	29	strains	strain	NNS
cord-315781-dejh8q22	218	30	that	that	WDT
cord-315781-dejh8q22	218	31	are	be	VBP
cord-315781-dejh8q22	218	32	used	use	VBN
cord-315781-dejh8q22	218	33	for	for	IN
cord-315781-dejh8q22	218	34	viral	viral	JJ
cord-315781-dejh8q22	218	35	production	production	NN
cord-315781-dejh8q22	218	36	are	be	VBP
cord-315781-dejh8q22	218	37	the	the	DT
cord-315781-dejh8q22	218	38	one	one	NN
cord-315781-dejh8q22	218	39	that	that	WDT
cord-315781-dejh8q22	218	40	will	will	MD
cord-315781-dejh8q22	218	41	cause	cause	VB
cord-315781-dejh8q22	218	42	an	an	DT
cord-315781-dejh8q22	218	43	outbreak	outbreak	NN
cord-315781-dejh8q22	218	44	in	in	IN
cord-315781-dejh8q22	218	45	the	the	DT
cord-315781-dejh8q22	218	46	following	follow	VBG
cord-315781-dejh8q22	218	47	season	season	NN
cord-315781-dejh8q22	218	48	.	.	.
cord-315781-dejh8q22	219	1	The	the	DT
cord-315781-dejh8q22	219	2	population	population	NN
cord-315781-dejh8q22	219	3	might	may	MD
cord-315781-dejh8q22	219	4	have	have	VB
cord-315781-dejh8q22	219	5	become	become	VBN
cord-315781-dejh8q22	219	6	immune	immune	JJ
cord-315781-dejh8q22	219	7	to	to	IN
cord-315781-dejh8q22	219	8	the	the	DT
cord-315781-dejh8q22	219	9	stock	stock	NN
cord-315781-dejh8q22	219	10	viruses	virus	NNS
cord-315781-dejh8q22	219	11	and	and	CC
cord-315781-dejh8q22	219	12	the	the	DT
cord-315781-dejh8q22	219	13	vaccine	vaccine	NN
cord-315781-dejh8q22	219	14	just	just	RB
cord-315781-dejh8q22	219	15	helps	help	VBZ
cord-315781-dejh8q22	219	16	to	to	TO
cord-315781-dejh8q22	219	17	recall	recall	VB
cord-315781-dejh8q22	219	18	the	the	DT
cord-315781-dejh8q22	219	19	memory	memory	NN
cord-315781-dejh8q22	219	20	of	of	IN
cord-315781-dejh8q22	219	21	these	these	DT
cord-315781-dejh8q22	219	22	strains	strain	NNS
cord-315781-dejh8q22	219	23	.	.	.
cord-315781-dejh8q22	220	1	Sequence	sequence	NN
cord-315781-dejh8q22	220	2	data	datum	NNS
cord-315781-dejh8q22	220	3	analysis	analysis	NN
cord-315781-dejh8q22	220	4	.	.	.
cord-315781-dejh8q22	221	1	All	all	DT
cord-315781-dejh8q22	221	2	of	of	IN
cord-315781-dejh8q22	221	3	the	the	DT
cord-315781-dejh8q22	221	4	sequence	sequence	NN
cord-315781-dejh8q22	221	5	data	datum	NNS
cord-315781-dejh8q22	221	6	used	use	VBN
cord-315781-dejh8q22	221	7	here	here	RB
cord-315781-dejh8q22	221	8	were	be	VBD
cord-315781-dejh8q22	221	9	obtained	obtain	VBN
cord-315781-dejh8q22	221	10	from	from	IN
cord-315781-dejh8q22	221	11	the	the	DT
cord-315781-dejh8q22	221	12	NCBI	NCBI	NNP
cord-315781-dejh8q22	221	13	database	database	NN
cord-315781-dejh8q22	221	14	(	(	-LRB-
cord-315781-dejh8q22	221	15	https://	https://	NNP
cord-315781-dejh8q22	221	16	www.ncbi.nlm.nih.gov/nuccore	www.ncbi.nlm.nih.gov/nuccore	NNP
cord-315781-dejh8q22	221	17	)	)	-RRB-
cord-315781-dejh8q22	221	18	.	.	.
cord-315781-dejh8q22	222	1	Data	datum	NNS
cord-315781-dejh8q22	222	2	pertaining	pertain	VBG
cord-315781-dejh8q22	222	3	to	to	IN
cord-315781-dejh8q22	222	4	amino	amino	NN
cord-315781-dejh8q22	222	5	acid	acid	NN
cord-315781-dejh8q22	222	6	sequences	sequence	NNS
cord-315781-dejh8q22	222	7	were	be	VBD
cord-315781-dejh8q22	222	8	used	use	VBN
cord-315781-dejh8q22	222	9	to	to	TO
cord-315781-dejh8q22	222	10	observe	observe	VB
cord-315781-dejh8q22	222	11	multiple	multiple	JJ
cord-315781-dejh8q22	222	12	subtypes	subtype	NNS
cord-315781-dejh8q22	222	13	or	or	CC
cord-315781-dejh8q22	222	14	hosts	host	NNS
cord-315781-dejh8q22	222	15	(	(	-LRB-
cord-315781-dejh8q22	222	16	Figs	fig	NNS
cord-315781-dejh8q22	222	17	.	.	.
cord-315781-dejh8q22	222	18	1	1	CD
cord-315781-dejh8q22	222	19	and	and	CC
cord-315781-dejh8q22	222	20	2	2	CD
cord-315781-dejh8q22	222	21	)	)	-RRB-
cord-315781-dejh8q22	222	22	,	,	,
cord-315781-dejh8q22	222	23	while	while	IN
cord-315781-dejh8q22	222	24	nucleotide	nucleotide	JJ
cord-315781-dejh8q22	222	25	sequences	sequence	NNS
cord-315781-dejh8q22	222	26	were	be	VBD
cord-315781-dejh8q22	222	27	used	use	VBN
cord-315781-dejh8q22	222	28	for	for	IN
cord-315781-dejh8q22	222	29	specific	specific	JJ
cord-315781-dejh8q22	222	30	subtypes	subtype	NNS
cord-315781-dejh8q22	222	31	(	(	-LRB-
cord-315781-dejh8q22	222	32	Figs	fig	NNS
cord-315781-dejh8q22	222	33	.	.	.
cord-315781-dejh8q22	223	1	3	3	LS
cord-315781-dejh8q22	223	2	-	-	SYM
cord-315781-dejh8q22	223	3	5	5	CD
cord-315781-dejh8q22	223	4	,	,	,
cord-315781-dejh8q22	223	5	S5	S5	NNP
cord-315781-dejh8q22	223	6	and	and	CC
cord-315781-dejh8q22	223	7	S6	S6	NNP
cord-315781-dejh8q22	223	8	)	)	-RRB-
cord-315781-dejh8q22	223	9	.	.	.
cord-315781-dejh8q22	224	1	Data	data	NN
cord-315781-dejh8q22	224	2	alignment	alignment	NN
cord-315781-dejh8q22	224	3	was	be	VBD
cord-315781-dejh8q22	224	4	performed	perform	VBN
cord-315781-dejh8q22	224	5	using	use	VBG
cord-315781-dejh8q22	224	6	MUSCLE	MUSCLE	NNP
cord-315781-dejh8q22	224	7	20	20	CD
cord-315781-dejh8q22	224	8	.	.	.
cord-315781-dejh8q22	225	1	All	all	PDT
cord-315781-dejh8q22	225	2	the	the	DT
cord-315781-dejh8q22	225	3	aligned	aligned	JJ
cord-315781-dejh8q22	225	4	sequences	sequence	NNS
cord-315781-dejh8q22	225	5	are	be	VBP
cord-315781-dejh8q22	225	6	presented	present	VBN
cord-315781-dejh8q22	225	7	in	in	IN
cord-315781-dejh8q22	225	8	Figs	Figs	NNP
cord-315781-dejh8q22	225	9	S1	S1	NNP
cord-315781-dejh8q22	225	10	,	,	,
cord-315781-dejh8q22	225	11	S2	S2	NNP
cord-315781-dejh8q22	225	12	and	and	CC
cord-315781-dejh8q22	225	13	S4	S4	NNP
cord-315781-dejh8q22	225	14	.	.	.
cord-315781-dejh8q22	226	1	The	the	DT
cord-315781-dejh8q22	226	2	sequence	sequence	NN
cord-315781-dejh8q22	226	3	matrix	matrix	NN
cord-315781-dejh8q22	226	4	was	be	VBD
cord-315781-dejh8q22	226	5	casted	cast	VBN
cord-315781-dejh8q22	226	6	to	to	TO
cord-315781-dejh8q22	226	7	direct	direct	JJ
cord-315781-dejh8q22	226	8	Principal	Principal	NNP
cord-315781-dejh8q22	226	9	Component	Component	NNP
cord-315781-dejh8q22	226	10	Analysis	Analysis	NNP
cord-315781-dejh8q22	226	11	(	(	-LRB-
cord-315781-dejh8q22	226	12	PCA	PCA	NNP
cord-315781-dejh8q22	226	13	)	)	-RRB-
cord-315781-dejh8q22	226	14	6	6	CD
cord-315781-dejh8q22	226	15	,	,	,
cord-315781-dejh8q22	226	16	which	which	WDT
cord-315781-dejh8q22	226	17	analyses	analyse	VBZ
cord-315781-dejh8q22	226	18	sequence	sequence	NN
cord-315781-dejh8q22	226	19	matrix	matrix	NN
cord-315781-dejh8q22	226	20	without	without	IN
cord-315781-dejh8q22	226	21	losing	lose	VBG
cord-315781-dejh8q22	226	22	any	any	DT
cord-315781-dejh8q22	226	23	of	of	IN
cord-315781-dejh8q22	226	24	original	original	JJ
cord-315781-dejh8q22	226	25	information	information	NN
cord-315781-dejh8q22	226	26	in	in	IN
cord-315781-dejh8q22	226	27	the	the	DT
cord-315781-dejh8q22	226	28	matrix	matrix	NN
cord-315781-dejh8q22	226	29	6	6	CD
cord-315781-dejh8q22	226	30	,	,	,
cord-315781-dejh8q22	226	31	using	use	VBG
cord-315781-dejh8q22	226	32	R	R	NNP
cord-315781-dejh8q22	226	33	21	21	CD
cord-315781-dejh8q22	226	34	.	.	.
cord-315781-dejh8q22	227	1	The	the	DT
cord-315781-dejh8q22	227	2	direct	direct	JJ
cord-315781-dejh8q22	227	3	PCA	PCA	NNP
cord-315781-dejh8q22	227	4	is	be	VBZ
cord-315781-dejh8q22	227	5	resistant	resistant	JJ
cord-315781-dejh8q22	227	6	to	to	IN
cord-315781-dejh8q22	227	7	differences	difference	NNS
cord-315781-dejh8q22	227	8	caused	cause	VBN
cord-315781-dejh8q22	227	9	by	by	IN
cord-315781-dejh8q22	227	10	the	the	DT
cord-315781-dejh8q22	227	11	alignment	alignment	NN
cord-315781-dejh8q22	227	12	:	:	:
cord-315781-dejh8q22	227	13	differences	difference	NNS
cord-315781-dejh8q22	227	14	in	in	IN
cord-315781-dejh8q22	227	15	the	the	DT
cord-315781-dejh8q22	227	16	conditions	condition	NNS
cord-315781-dejh8q22	227	17	or	or	CC
cord-315781-dejh8q22	227	18	the	the	DT
cord-315781-dejh8q22	227	19	alignment	alignment	NN
cord-315781-dejh8q22	227	20	methods	method	NNS
cord-315781-dejh8q22	227	21	may	may	MD
cord-315781-dejh8q22	227	22	not	not	RB
cord-315781-dejh8q22	227	23	alter	alter	VB
cord-315781-dejh8q22	227	24	the	the	DT
cord-315781-dejh8q22	227	25	results	result	NNS
cord-315781-dejh8q22	227	26	practically	practically	RB
cord-315781-dejh8q22	227	27	6	6	CD
cord-315781-dejh8q22	227	28	.	.	.
cord-315781-dejh8q22	228	1	The	the	DT
cord-315781-dejh8q22	228	2	sequence	sequence	NN
cord-315781-dejh8q22	228	3	matrix	matrix	NN
cord-315781-dejh8q22	228	4	were	be	VBD
cord-315781-dejh8q22	228	5	translated	translate	VBN
cord-315781-dejh8q22	228	6	into	into	IN
cord-315781-dejh8q22	228	7	a	a	DT
cord-315781-dejh8q22	228	8	Boolean	boolean	JJ
cord-315781-dejh8q22	228	9	vector	vector	NN
cord-315781-dejh8q22	228	10	X	x	NN
cord-315781-dejh8q22	228	11	;	;	:
cord-315781-dejh8q22	228	12	for	for	IN
cord-315781-dejh8q22	228	13	n	n	CD
cord-315781-dejh8q22	228	14	samples	sample	NNS
cord-315781-dejh8q22	228	15	of	of	IN
cord-315781-dejh8q22	228	16	l	l	NN
cord-315781-dejh8q22	228	17	bases	basis	NNS
cord-315781-dejh8q22	228	18	,	,	,
cord-315781-dejh8q22	228	19	X	X	NNP
cord-315781-dejh8q22	228	20	is	be	VBZ
cord-315781-dejh8q22	228	21	a	a	DT
cord-315781-dejh8q22	228	22	matrix	matrix	NN
cord-315781-dejh8q22	228	23	of	of	IN
cord-315781-dejh8q22	228	24	n	n	NNP
cord-315781-dejh8q22	228	25	×	×	NNP
cord-315781-dejh8q22	228	26	5	5	CD
cord-315781-dejh8q22	228	27	l	l	NN
cord-315781-dejh8q22	228	28	,	,	,
cord-315781-dejh8q22	228	29	which	which	WDT
cord-315781-dejh8q22	228	30	correspond	correspond	VBP
cord-315781-dejh8q22	228	31	to	to	IN
cord-315781-dejh8q22	228	32	the	the	DT
cord-315781-dejh8q22	228	33	nucleotides	nucleotide	NNS
cord-315781-dejh8q22	228	34	and	and	CC
cord-315781-dejh8q22	228	35	inserted	insert	VBN
cord-315781-dejh8q22	228	36	space	space	NN
cord-315781-dejh8q22	228	37	"	"	''
cord-315781-dejh8q22	228	38	-	-	:
cord-315781-dejh8q22	228	39	"	"	''
cord-315781-dejh8q22	228	40	for	for	IN
cord-315781-dejh8q22	228	41	alignment	alignment	NN
cord-315781-dejh8q22	228	42	.	.	.
cord-315781-dejh8q22	229	1	A	a	DT
cord-315781-dejh8q22	229	2	mean	mean	JJ
cord-315781-dejh8q22	229	3	vector	vector	NN
cord-315781-dejh8q22	229	4	→	→	IN
cord-315781-dejh8q22	229	5	m	m	NN
cord-315781-dejh8q22	229	6	was	be	VBD
cord-315781-dejh8q22	229	7	estimated	estimate	VBN
cord-315781-dejh8q22	229	8	as	as	IN
cord-315781-dejh8q22	229	9	→	→	NN
cord-315781-dejh8q22	229	10	=	=	SYM
cord-315781-dejh8q22	229	11	∑	∑	NNP
cord-315781-dejh8q22	229	12	=	=	SYM
cord-315781-dejh8q22	229	13	n	n	NN
cord-315781-dejh8q22	229	14	X	X	NNP
cord-315781-dejh8q22	229	15	m	m	NNP
cord-315781-dejh8q22	229	16	/	/	SYM
cord-315781-dejh8q22	229	17	i	i	NNP
cord-315781-dejh8q22	229	18	n	n	NNP
cord-315781-dejh8q22	229	19	i	i	NNP
cord-315781-dejh8q22	229	20	j	j	NNP
cord-315781-dejh8q22	229	21	1	1	CD
cord-315781-dejh8q22	229	22	,	,	,
cord-315781-dejh8q22	229	23	,	,	,
cord-315781-dejh8q22	229	24	where	where	WRB
cord-315781-dejh8q22	229	25	j	j	NNP
cord-315781-dejh8q22	229	26	=	=	SYM
cord-315781-dejh8q22	229	27	1	1	CD
cord-315781-dejh8q22	229	28	,	,	,
cord-315781-dejh8q22	229	29	2	2	CD
cord-315781-dejh8q22	229	30	,	,	,
cord-315781-dejh8q22	229	31	,	,	,
cord-315781-dejh8q22	229	32	,	,	,
cord-315781-dejh8q22	229	33	,	,	,
cord-315781-dejh8q22	230	1	5	5	CD
cord-315781-dejh8q22	230	2	l.	l.	NNP
cord-315781-dejh8q22	231	1	The	the	DT
cord-315781-dejh8q22	231	2	boolean	boolean	JJ
cord-315781-dejh8q22	231	3	vector	vector	NN
cord-315781-dejh8q22	231	4	was	be	VBD
cord-315781-dejh8q22	231	5	then	then	RB
cord-315781-dejh8q22	231	6	catered	cater	VBN
cord-315781-dejh8q22	231	7	to	to	TO
cord-315781-dejh8q22	231	8	estimate	estimate	VB
cord-315781-dejh8q22	231	9	differences	difference	NNS
cord-315781-dejh8q22	231	10	to	to	IN
cord-315781-dejh8q22	231	11	the	the	DT
cord-315781-dejh8q22	231	12	mean	mean	JJ
cord-315781-dejh8q22	231	13	vector	vector	NN
cord-315781-dejh8q22	231	14	,	,	,
cord-315781-dejh8q22	231	15	,	,	,
cord-315781-dejh8q22	231	16	where	where	WRB
cord-315781-dejh8q22	231	17	k	k	NN
cord-315781-dejh8q22	231	18	=	=	SYM
cord-315781-dejh8q22	231	19	1	1	CD
cord-315781-dejh8q22	231	20	,	,	,
cord-315781-dejh8q22	231	21	2	2	CD
cord-315781-dejh8q22	231	22	,	,	,
cord-315781-dejh8q22	231	23	,	,	,
cord-315781-dejh8q22	231	24	,	,	,
cord-315781-dejh8q22	231	25	,	,	,
cord-315781-dejh8q22	231	26	n.	n.	NN
cord-315781-dejh8q22	231	27	Then	then	RB
cord-315781-dejh8q22	231	28	D	D	NNP
cord-315781-dejh8q22	231	29	was	be	VBD
cord-315781-dejh8q22	231	30	subjected	subject	VBN
cord-315781-dejh8q22	231	31	for	for	IN
cord-315781-dejh8q22	231	32	singular	singular	JJ
cord-315781-dejh8q22	231	33	value	value	NN
cord-315781-dejh8q22	231	34	decomposition	decomposition	NN
cord-315781-dejh8q22	231	35	as	as	IN
cord-315781-dejh8q22	231	36	Σ	Σ	NNP
cord-315781-dejh8q22	231	37	=	=	SYM
cord-315781-dejh8q22	231	38	⁎	⁎	NN
cord-315781-dejh8q22	231	39	D	D	NNP
cord-315781-dejh8q22	231	40	L	l	NN
cord-315781-dejh8q22	231	41	R	r	NN
cord-315781-dejh8q22	231	42	.	.	.
cord-315781-dejh8q22	232	1	Scaled	scale	VBN
cord-315781-dejh8q22	232	2	values	value	NNS
cord-315781-dejh8q22	232	3	of	of	IN
cord-315781-dejh8q22	232	4	the	the	DT
cord-315781-dejh8q22	232	5	Principal	Principal	NNP
cord-315781-dejh8q22	232	6	Components	Components	NNP
cord-315781-dejh8q22	232	7	(	(	-LRB-
cord-315781-dejh8q22	232	8	sPC	spc	ADD
cord-315781-dejh8q22	232	9	)	)	-RRB-
cord-315781-dejh8q22	232	10	were	be	VBD
cord-315781-dejh8q22	232	11	found	find	VBN
cord-315781-dejh8q22	232	12	by	by	IN
cord-315781-dejh8q22	232	13	placing	place	VBG
cord-315781-dejh8q22	232	14	back	back	RP
cord-315781-dejh8q22	232	15	the	the	DT
cord-315781-dejh8q22	232	16	singular	singular	JJ
cord-315781-dejh8q22	232	17	values	value	NNS
cord-315781-dejh8q22	232	18	Σ	Σ	NNP
cord-315781-dejh8q22	232	19	to	to	IN
cord-315781-dejh8q22	232	20	the	the	DT
cord-315781-dejh8q22	232	21	unitary	unitary	JJ
cord-315781-dejh8q22	232	22	matrixes	matrix	NNS
cord-315781-dejh8q22	232	23	L	l	NN
cord-315781-dejh8q22	232	24	or	or	CC
cord-315781-dejh8q22	232	25	R	r	NN
cord-315781-dejh8q22	232	26	;	;	:
cord-315781-dejh8q22	232	27	those	those	DT
cord-315781-dejh8q22	232	28	for	for	IN
cord-315781-dejh8q22	232	29	the	the	DT
cord-315781-dejh8q22	232	30	samples	sample	NNS
cord-315781-dejh8q22	232	31	were	be	VBD
cord-315781-dejh8q22	232	32	estimated	estimate	VBN
cord-315781-dejh8q22	232	33	as	as	IN
cord-315781-dejh8q22	232	34	Σ	Σ	NNP
cord-315781-dejh8q22	232	35	=	=	SYM
cord-315781-dejh8q22	232	36	l	l	NN
cord-315781-dejh8q22	232	37	L	L	NNP
cord-315781-dejh8q22	232	38	sPC	sPC	NNP
cord-315781-dejh8q22	232	39	/	/	SYM
cord-315781-dejh8q22	232	40	s	s	NNS
cord-315781-dejh8q22	232	41	and	and	CC
cord-315781-dejh8q22	232	42	the	the	DT
cord-315781-dejh8q22	232	43	nucleotide	nucleotide	JJ
cord-315781-dejh8q22	232	44	bases	basis	NNS
cord-315781-dejh8q22	232	45	were	be	VBD
cord-315781-dejh8q22	232	46	estimated	estimate	VBN
cord-315781-dejh8q22	232	47	as	as	IN
cord-315781-dejh8q22	232	48	Σ	Σ	NNP
cord-315781-dejh8q22	232	49	=	=	SYM
cord-315781-dejh8q22	232	50	n	n	NN
cord-315781-dejh8q22	232	51	R	r	NN
cord-315781-dejh8q22	232	52	sPC	spc	NN
cord-315781-dejh8q22	232	53	/	/	SYM
cord-315781-dejh8q22	232	54	n	n	NN
cord-315781-dejh8q22	232	55	.	.	.
cord-315781-dejh8q22	233	1	They	-PRON-	PRP
cord-315781-dejh8q22	233	2	were	be	VBD
cord-315781-dejh8q22	233	3	scaled	scale	VBN
cord-315781-dejh8q22	233	4	for	for	IN
cord-315781-dejh8q22	233	5	comparisons	comparison	NNS
cord-315781-dejh8q22	233	6	that	that	WDT
cord-315781-dejh8q22	233	7	enables	enable	VBZ
cord-315781-dejh8q22	233	8	to	to	TO
cord-315781-dejh8q22	233	9	identify	identify	VB
cord-315781-dejh8q22	233	10	which	which	WDT
cord-315781-dejh8q22	233	11	base	base	NN
cord-315781-dejh8q22	233	12	contributed	contribute	VBD
cord-315781-dejh8q22	233	13	for	for	IN
cord-315781-dejh8q22	233	14	the	the	DT
cord-315781-dejh8q22	233	15	differences	difference	NNS
cord-315781-dejh8q22	233	16	of	of	IN
cord-315781-dejh8q22	233	17	samples	sample	NNS
cord-315781-dejh8q22	233	18	22	22	CD
cord-315781-dejh8q22	233	19	.	.	.
cord-315781-dejh8q22	234	1	Therefore	therefore	RB
cord-315781-dejh8q22	234	2	,	,	,
cord-315781-dejh8q22	234	3	each	each	DT
cord-315781-dejh8q22	234	4	sPC	spc	XX
cord-315781-dejh8q22	234	5	presents	present	VBZ
cord-315781-dejh8q22	234	6	directions	direction	NNS
cord-315781-dejh8q22	234	7	and	and	CC
cord-315781-dejh8q22	234	8	distances	distance	NNS
cord-315781-dejh8q22	234	9	of	of	IN
cord-315781-dejh8q22	234	10	the	the	DT
cord-315781-dejh8q22	234	11	differences	difference	NNS
cord-315781-dejh8q22	234	12	,	,	,
cord-315781-dejh8q22	234	13	which	which	WDT
cord-315781-dejh8q22	234	14	were	be	VBD
cord-315781-dejh8q22	234	15	recorded	record	VBN
cord-315781-dejh8q22	234	16	by	by	IN
cord-315781-dejh8q22	234	17	the	the	DT
cord-315781-dejh8q22	234	18	unitary	unitary	JJ
cord-315781-dejh8q22	234	19	matrix	matrix	NN
cord-315781-dejh8q22	234	20	and	and	CC
cord-315781-dejh8q22	234	21	the	the	DT
cord-315781-dejh8q22	234	22	singular	singular	JJ
cord-315781-dejh8q22	234	23	value	value	NN
cord-315781-dejh8q22	234	24	,	,	,
cord-315781-dejh8q22	234	25	respectively	respectively	RB
cord-315781-dejh8q22	234	26	,	,	,
cord-315781-dejh8q22	234	27	as	as	IN
cord-315781-dejh8q22	234	28	sets	set	NNS
cord-315781-dejh8q22	234	29	of	of	IN
cord-315781-dejh8q22	234	30	orthogonal	orthogonal	JJ
cord-315781-dejh8q22	234	31	vectors	vector	NNS
cord-315781-dejh8q22	234	32	executed	execute	VBN
cord-315781-dejh8q22	234	33	as	as	IN
cord-315781-dejh8q22	234	34	the	the	DT
cord-315781-dejh8q22	234	35	columns	column	NNS
cord-315781-dejh8q22	234	36	of	of	IN
cord-315781-dejh8q22	234	37	the	the	DT
cord-315781-dejh8q22	234	38	sPC	spc	NN
cord-315781-dejh8q22	234	39	matrixes	matrix	NNS
cord-315781-dejh8q22	234	40	.	.	.
cord-315781-dejh8q22	235	1	Scripts	script	NNS
cord-315781-dejh8q22	235	2	of	of	IN
cord-315781-dejh8q22	235	3	the	the	DT
cord-315781-dejh8q22	235	4	R	r	NN
cord-315781-dejh8q22	235	5	used	use	VBN
cord-315781-dejh8q22	235	6	for	for	IN
cord-315781-dejh8q22	235	7	the	the	DT
cord-315781-dejh8q22	235	8	calculation	calculation	NN
cord-315781-dejh8q22	235	9	is	be	VBZ
cord-315781-dejh8q22	235	10	presented	present	VBN
cord-315781-dejh8q22	235	11	in	in	IN
cord-315781-dejh8q22	235	12	Fig	Fig	NNP
cord-315781-dejh8q22	235	13	.	.	.
cord-315781-dejh8q22	236	1	S2	S2	NNP
cord-315781-dejh8q22	236	2	.	.	.
cord-315781-dejh8q22	237	1	PC	pc	NN
cord-315781-dejh8q22	237	2	signs	sign	NNS
cord-315781-dejh8q22	237	3	were	be	VBD
cord-315781-dejh8q22	237	4	derived	derive	VBN
cord-315781-dejh8q22	237	5	in	in	IN
cord-315781-dejh8q22	237	6	a	a	DT
cord-315781-dejh8q22	237	7	random	random	JJ
cord-315781-dejh8q22	237	8	manner	manner	NN
cord-315781-dejh8q22	237	9	;	;	:
cord-315781-dejh8q22	237	10	thus	thus	RB
cord-315781-dejh8q22	237	11	,	,	,
cord-315781-dejh8q22	237	12	the	the	DT
cord-315781-dejh8q22	237	13	results	result	NNS
cord-315781-dejh8q22	237	14	were	be	VBD
cord-315781-dejh8q22	237	15	adjusted	adjust	VBN
cord-315781-dejh8q22	237	16	to	to	TO
cord-315781-dejh8q22	237	17	align	align	VB
cord-315781-dejh8q22	237	18	different	different	JJ
cord-315781-dejh8q22	237	19	presentations	presentation	NNS
cord-315781-dejh8q22	237	20	for	for	IN
cord-315781-dejh8q22	237	21	comparison	comparison	NN
cord-315781-dejh8q22	237	22	.	.	.
cord-315781-dejh8q22	238	1	A	a	DT
cord-315781-dejh8q22	238	2	starter	starter	NN
cord-315781-dejh8q22	238	3	kit	kit	NN
cord-315781-dejh8q22	238	4	for	for	IN
cord-315781-dejh8q22	238	5	the	the	DT
cord-315781-dejh8q22	238	6	direct	direct	JJ
cord-315781-dejh8q22	238	7	PCA	PCA	NNP
cord-315781-dejh8q22	238	8	is	be	VBZ
cord-315781-dejh8q22	238	9	available	available	JJ
cord-315781-dejh8q22	238	10	in	in	IN
cord-315781-dejh8q22	238	11	the	the	DT
cord-315781-dejh8q22	238	12	accompanying	accompanying	JJ
cord-315781-dejh8q22	238	13	article	article	NN
cord-315781-dejh8q22	238	14	6	6	CD
cord-315781-dejh8q22	238	15	.	.	.
cord-315781-dejh8q22	239	1	The	the	DT
cord-315781-dejh8q22	239	2	3D	3d	JJ
cord-315781-dejh8q22	239	3	structures	structure	NNS
cord-315781-dejh8q22	239	4	.	.	.
cord-315781-dejh8q22	240	1	The	the	DT
cord-315781-dejh8q22	240	2	PDB	PDB	NNP
cord-315781-dejh8q22	240	3	files	file	NNS
cord-315781-dejh8q22	240	4	were	be	VBD
cord-315781-dejh8q22	240	5	obtained	obtain	VBN
cord-315781-dejh8q22	240	6	from	from	IN
cord-315781-dejh8q22	240	7	the	the	DT
cord-315781-dejh8q22	240	8	RCSB	RCSB	NNP
cord-315781-dejh8q22	240	9	Protein	Protein	NNP
cord-315781-dejh8q22	240	10	Data	Data	NNP
cord-315781-dejh8q22	240	11	Bank	Bank	NNP
cord-315781-dejh8q22	240	12	(	(	-LRB-
cord-315781-dejh8q22	240	13	https://www.rcsb.org/	https://www.rcsb.org/	ADD
cord-315781-dejh8q22	240	14	)	)	-RRB-
cord-315781-dejh8q22	240	15	.	.	.
cord-315781-dejh8q22	241	1	Position	position	NN
cord-315781-dejh8q22	241	2	data	datum	NNS
cord-315781-dejh8q22	241	3	were	be	VBD
cord-315781-dejh8q22	241	4	found	find	VBN
cord-315781-dejh8q22	241	5	using	use	VBG
cord-315781-dejh8q22	241	6	ATOM	atom	NN
cord-315781-dejh8q22	241	7	header	header	NN
cord-315781-dejh8q22	241	8	:	:	:
cord-315781-dejh8q22	241	9	i.e.	i.e.	FW
cord-315781-dejh8q22	241	10	,	,	,
cord-315781-dejh8q22	241	11	positions	position	NNS
cord-315781-dejh8q22	241	12	at	at	IN
cord-315781-dejh8q22	241	13	the	the	DT
cord-315781-dejh8q22	241	14	alpha	alpha	NN
cord-315781-dejh8q22	241	15	carbon	carbon	NN
cord-315781-dejh8q22	241	16	of	of	IN
cord-315781-dejh8q22	241	17	amino	amino	NN
cord-315781-dejh8q22	241	18	acids	acid	NNS
cord-315781-dejh8q22	241	19	were	be	VBD
cord-315781-dejh8q22	241	20	connected	connect	VBN
cord-315781-dejh8q22	241	21	to	to	TO
cord-315781-dejh8q22	241	22	draw	draw	VB
cord-315781-dejh8q22	241	23	the	the	DT
cord-315781-dejh8q22	241	24	structure	structure	NN
cord-315781-dejh8q22	241	25	and	and	CC
cord-315781-dejh8q22	241	26	were	be	VBD
cord-315781-dejh8q22	241	27	then	then	RB
cord-315781-dejh8q22	241	28	aligned	align	VBN
cord-315781-dejh8q22	241	29	using	use	VBG
cord-315781-dejh8q22	241	30	PCA	PCA	NNP
cord-315781-dejh8q22	241	31	.	.	.
cord-315781-dejh8q22	242	1	The	the	DT
cord-315781-dejh8q22	242	2	HTML5	HTML5	NNP
cord-315781-dejh8q22	242	3	output	output	NN
cord-315781-dejh8q22	242	4	was	be	VBD
cord-315781-dejh8q22	242	5	generated	generate	VBN
cord-315781-dejh8q22	242	6	using	use	VBG
cord-315781-dejh8q22	242	7	the	the	DT
cord-315781-dejh8q22	242	8	writeWebGL	writeWebGL	NNP
cord-315781-dejh8q22	242	9	function	function	NN
cord-315781-dejh8q22	242	10	of	of	IN
cord-315781-dejh8q22	242	11	the	the	DT
cord-315781-dejh8q22	242	12	rgl	rgl	NNP
cord-315781-dejh8q22	242	13	package	package	NN
cord-315781-dejh8q22	242	14	of	of	IN
cord-315781-dejh8q22	242	15	R	r	NN
cord-315781-dejh8q22	242	16	(	(	-LRB-
cord-315781-dejh8q22	242	17	https://cran.r-project.org/web/packages/rgl/vignettes/rgl.html	https://cran.r-project.org/web/packages/rgl/vignettes/rgl.html	''
cord-315781-dejh8q22	242	18	)	)	-RRB-
cord-315781-dejh8q22	242	19	.	.	.
cord-315781-dejh8q22	243	1	The	the	DT
cord-315781-dejh8q22	243	2	evolution	evolution	NN
cord-315781-dejh8q22	243	3	of	of	IN
cord-315781-dejh8q22	243	4	seasonal	seasonal	JJ
cord-315781-dejh8q22	243	5	influenza	influenza	NN
cord-315781-dejh8q22	243	6	viruses	virus	NNS
cord-315781-dejh8q22	243	7	Avian	avian	JJ
cord-315781-dejh8q22	243	8	influenza	influenza	NN
cord-315781-dejh8q22	243	9	:	:	:
cord-315781-dejh8q22	243	10	assessing	assess	VBG
cord-315781-dejh8q22	243	11	the	the	DT
cord-315781-dejh8q22	243	12	pandemic	pandemic	NN
cord-315781-dejh8q22	243	13	threat	threat	NN
cord-315781-dejh8q22	243	14	Influenza	Influenza	NNP
cord-315781-dejh8q22	243	15	Virus	Virus	NNP
cord-315781-dejh8q22	243	16	Evolution	Evolution	NNP
cord-315781-dejh8q22	243	17	,	,	,
cord-315781-dejh8q22	243	18	Host	Host	NNP
cord-315781-dejh8q22	243	19	Adaptation	Adaptation	NNP
cord-315781-dejh8q22	243	20	,	,	,
cord-315781-dejh8q22	243	21	and	and	CC
cord-315781-dejh8q22	243	22	Pandemic	Pandemic	NNP
cord-315781-dejh8q22	243	23	Formation	Formation	NNP
cord-315781-dejh8q22	243	24	Historical	historical	JJ
cord-315781-dejh8q22	243	25	perspective	perspective	NN
cord-315781-dejh8q22	243	26	-	-	:
cord-315781-dejh8q22	243	27	Emergence	emergence	NN
cord-315781-dejh8q22	243	28	of	of	IN
cord-315781-dejh8q22	243	29	influenza	influenza	NN
cord-315781-dejh8q22	243	30	A	a	NN
cord-315781-dejh8q22	243	31	(	(	-LRB-
cord-315781-dejh8q22	243	32	H1N1	H1N1	NNP
cord-315781-dejh8q22	243	33	)	)	-RRB-
cord-315781-dejh8q22	243	34	viruses	virus	NNS
cord-315781-dejh8q22	244	1	The	the	DT
cord-315781-dejh8q22	244	2	pig	pig	NN
cord-315781-dejh8q22	244	3	as	as	IN
cord-315781-dejh8q22	244	4	a	a	DT
cord-315781-dejh8q22	244	5	mixing	mix	VBG
cord-315781-dejh8q22	244	6	vessel	vessel	NN
cord-315781-dejh8q22	244	7	for	for	IN
cord-315781-dejh8q22	244	8	influenza	influenza	NN
cord-315781-dejh8q22	244	9	viruses	virus	NNS
cord-315781-dejh8q22	244	10	:	:	:
cord-315781-dejh8q22	244	11	Human	human	JJ
cord-315781-dejh8q22	244	12	and	and	CC
cord-315781-dejh8q22	244	13	veterinary	veterinary	JJ
cord-315781-dejh8q22	244	14	implications	implication	NNS
cord-315781-dejh8q22	244	15	Principal	Principal	NNP
cord-315781-dejh8q22	244	16	Component	Component	NNP
cord-315781-dejh8q22	244	17	Analysis	Analysis	NNP
cord-315781-dejh8q22	244	18	applied	apply	VBD
cord-315781-dejh8q22	244	19	directly	directly	RB
cord-315781-dejh8q22	244	20	to	to	IN
cord-315781-dejh8q22	244	21	Sequence	Sequence	NNP
cord-315781-dejh8q22	244	22	Matrix	Matrix	NNP
cord-315781-dejh8q22	244	23	Molecular	Molecular	NNP
cord-315781-dejh8q22	244	24	phylogenetics	phylogenetic	NNS
cord-315781-dejh8q22	244	25	:	:	:
cord-315781-dejh8q22	244	26	principles	principle	NNS
cord-315781-dejh8q22	244	27	and	and	CC
cord-315781-dejh8q22	244	28	practice	practice	VB
cord-315781-dejh8q22	244	29	Origins	origin	NNS
cord-315781-dejh8q22	244	30	and	and	CC
cord-315781-dejh8q22	244	31	evolutionary	evolutionary	JJ
cord-315781-dejh8q22	244	32	genomics	genomic	NNS
cord-315781-dejh8q22	244	33	of	of	IN
cord-315781-dejh8q22	244	34	the	the	DT
cord-315781-dejh8q22	244	35	2009	2009	CD
cord-315781-dejh8q22	244	36	swine	swine	NN
cord-315781-dejh8q22	244	37	-	-	HYPH
cord-315781-dejh8q22	244	38	origin	origin	NN
cord-315781-dejh8q22	244	39	H1N1	H1N1	NNP
cord-315781-dejh8q22	244	40	influenza	influenza	NN
cord-315781-dejh8q22	244	41	A	a	DT
cord-315781-dejh8q22	244	42	epidemic	epidemic	NN
cord-315781-dejh8q22	244	43	Antigenic	antigenic	JJ
cord-315781-dejh8q22	244	44	and	and	CC
cord-315781-dejh8q22	244	45	genetic	genetic	JJ
cord-315781-dejh8q22	244	46	characteristics	characteristic	NNS
cord-315781-dejh8q22	244	47	of	of	IN
cord-315781-dejh8q22	244	48	swine	swine	NN
cord-315781-dejh8q22	244	49	-	-	HYPH
cord-315781-dejh8q22	244	50	origin	origin	NN
cord-315781-dejh8q22	244	51	2009	2009	CD
cord-315781-dejh8q22	244	52	A(H1N1	a(h1n1	CD
cord-315781-dejh8q22	244	53	)	)	-RRB-
cord-315781-dejh8q22	245	1	influenza	influenza	NN
cord-315781-dejh8q22	245	2	viruses	virus	NNS
cord-315781-dejh8q22	245	3	circulating	circulate	VBG
cord-315781-dejh8q22	245	4	in	in	IN
cord-315781-dejh8q22	245	5	humans	human	NNS
cord-315781-dejh8q22	245	6	Influenza	Influenza	NNP
cord-315781-dejh8q22	245	7	A	A	NNP
cord-315781-dejh8q22	245	8	Viruses	Viruses	NNPS
cord-315781-dejh8q22	245	9	of	of	IN
cord-315781-dejh8q22	245	10	Human	Human	NNP
cord-315781-dejh8q22	245	11	Origin	Origin	NNP
cord-315781-dejh8q22	245	12	in	in	IN
cord-315781-dejh8q22	245	13	Swine	Swine	NNP
cord-315781-dejh8q22	245	14	,	,	,
cord-315781-dejh8q22	245	15	Brazil	Brazil	NNP
cord-315781-dejh8q22	245	16	.	.	.
cord-315781-dejh8q22	246	1	Emerging	emerge	VBG
cord-315781-dejh8q22	246	2	Infectious	Infectious	NNP
cord-315781-dejh8q22	246	3	Disease	Disease	NNP
cord-315781-dejh8q22	246	4	journal	journal	NN
cord-315781-dejh8q22	246	5	21	21	CD
cord-315781-dejh8q22	246	6	Origins	Origins	NNPS
cord-315781-dejh8q22	246	7	of	of	IN
cord-315781-dejh8q22	246	8	the	the	DT
cord-315781-dejh8q22	246	9	2009	2009	CD
cord-315781-dejh8q22	246	10	H1N1	H1N1	NNP
cord-315781-dejh8q22	246	11	influenza	influenza	NN
cord-315781-dejh8q22	246	12	pandemic	pandemic	NN
cord-315781-dejh8q22	246	13	in	in	IN
cord-315781-dejh8q22	246	14	swine	swine	NN
cord-315781-dejh8q22	246	15	in	in	IN
cord-315781-dejh8q22	246	16	Mexico	Mexico	NNP
cord-315781-dejh8q22	246	17	Global	Global	NNP
cord-315781-dejh8q22	246	18	migration	migration	NN
cord-315781-dejh8q22	246	19	of	of	IN
cord-315781-dejh8q22	246	20	influenza	influenza	NN
cord-315781-dejh8q22	246	21	A	a	DT
cord-315781-dejh8q22	246	22	viruses	virus	NNS
cord-315781-dejh8q22	246	23	in	in	IN
cord-315781-dejh8q22	246	24	swine	swine	NN
cord-315781-dejh8q22	247	1	The	the	DT
cord-315781-dejh8q22	247	2	persistent	persistent	JJ
cord-315781-dejh8q22	247	3	legacy	legacy	NN
cord-315781-dejh8q22	247	4	of	of	IN
cord-315781-dejh8q22	247	5	the	the	DT
cord-315781-dejh8q22	247	6	1918	1918	CD
cord-315781-dejh8q22	247	7	influenza	influenza	NN
cord-315781-dejh8q22	247	8	virus	virus	NN
cord-315781-dejh8q22	247	9	The	the	DT
cord-315781-dejh8q22	247	10	Stanford	Stanford	NNP
cord-315781-dejh8q22	247	11	Encyclopedia	Encyclopedia	NNP
cord-315781-dejh8q22	247	12	of	of	IN
cord-315781-dejh8q22	247	13	Philosophy	Philosophy	NNP
cord-315781-dejh8q22	247	14	Concerns	concern	NNS
cord-315781-dejh8q22	247	15	regarding	regard	VBG
cord-315781-dejh8q22	247	16	the	the	DT
cord-315781-dejh8q22	247	17	deterioration	deterioration	NN
cord-315781-dejh8q22	247	18	of	of	IN
cord-315781-dejh8q22	247	19	objectivity	objectivity	NN
cord-315781-dejh8q22	247	20	in	in	IN
cord-315781-dejh8q22	247	21	molecular	molecular	JJ
cord-315781-dejh8q22	247	22	biology	biology	NN
cord-315781-dejh8q22	247	23	Characterization	characterization	NN
cord-315781-dejh8q22	247	24	of	of	IN
cord-315781-dejh8q22	247	25	the	the	DT
cord-315781-dejh8q22	247	26	1918	1918	CD
cord-315781-dejh8q22	247	27	influenza	influenza	NN
cord-315781-dejh8q22	247	28	virus	virus	NN
cord-315781-dejh8q22	247	29	polymerase	polymerase	NN
cord-315781-dejh8q22	247	30	genes	gene	NNS
cord-315781-dejh8q22	247	31	Genetic	genetic	JJ
cord-315781-dejh8q22	247	32	reassortment	reassortment	NN
cord-315781-dejh8q22	247	33	of	of	IN
cord-315781-dejh8q22	247	34	avian	avian	JJ
cord-315781-dejh8q22	247	35	,	,	,
cord-315781-dejh8q22	247	36	swine	swine	NN
cord-315781-dejh8q22	247	37	,	,	,
cord-315781-dejh8q22	247	38	and	and	CC
cord-315781-dejh8q22	247	39	human	human	JJ
cord-315781-dejh8q22	247	40	influenza	influenza	NN
cord-315781-dejh8q22	247	41	A	a	DT
cord-315781-dejh8q22	247	42	viruses	virus	NNS
cord-315781-dejh8q22	247	43	in	in	IN
cord-315781-dejh8q22	247	44	American	american	JJ
cord-315781-dejh8q22	247	45	pigs	pig	NNS
cord-315781-dejh8q22	248	1	The	the	DT
cord-315781-dejh8q22	248	2	Re	re	NN
cord-315781-dejh8q22	248	3	-	-	HYPH
cord-315781-dejh8q22	248	4	Emergence	emergence	NN
cord-315781-dejh8q22	248	5	of	of	IN
cord-315781-dejh8q22	248	6	H1N1	H1N1	NNP
cord-315781-dejh8q22	248	7	Influenza	Influenza	NNP
cord-315781-dejh8q22	248	8	Virus	Virus	NNP
cord-315781-dejh8q22	248	9	in	in	IN
cord-315781-dejh8q22	248	10	1977	1977	CD
cord-315781-dejh8q22	248	11	:	:	:
cord-315781-dejh8q22	249	1	A	a	DT
cord-315781-dejh8q22	249	2	Cautionary	cautionary	JJ
cord-315781-dejh8q22	249	3	Tale	tale	NN
cord-315781-dejh8q22	249	4	for	for	IN
cord-315781-dejh8q22	249	5	Estimating	Estimating	NNP
cord-315781-dejh8q22	249	6	Divergence	Divergence	NNP
cord-315781-dejh8q22	249	7	Times	Times	NNP
cord-315781-dejh8q22	249	8	Using	use	VBG
cord-315781-dejh8q22	249	9	Biologically	biologically	RB
cord-315781-dejh8q22	249	10	Unrealistic	unrealistic	JJ
cord-315781-dejh8q22	249	11	Sampling	Sampling	NNP
cord-315781-dejh8q22	249	12	Dates	Dates	NNPS
cord-315781-dejh8q22	249	13	&	&	CC
cord-315781-dejh8q22	249	14	Related	Related	NNP
cord-315781-dejh8q22	249	15	Influenza	Influenza	NNP
cord-315781-dejh8q22	249	16	,	,	,
cord-315781-dejh8q22	249	17	V.	V.	NNP
cord-315781-dejh8q22	249	18	Role	Role	NNP
cord-315781-dejh8q22	249	19	for	for	IN
cord-315781-dejh8q22	249	20	migratory	migratory	JJ
cord-315781-dejh8q22	249	21	wild	wild	JJ
cord-315781-dejh8q22	249	22	birds	bird	NNS
cord-315781-dejh8q22	249	23	in	in	IN
cord-315781-dejh8q22	249	24	the	the	DT
cord-315781-dejh8q22	249	25	global	global	JJ
cord-315781-dejh8q22	249	26	spread	spread	NN
cord-315781-dejh8q22	249	27	of	of	IN
cord-315781-dejh8q22	249	28	avian	avian	JJ
cord-315781-dejh8q22	249	29	influenza	influenza	NN
cord-315781-dejh8q22	249	30	H5N8	H5N8	NNP
cord-315781-dejh8q22	249	31	MUSCLE	muscle	NN
cord-315781-dejh8q22	249	32	:	:	:
cord-315781-dejh8q22	249	33	multiple	multiple	JJ
cord-315781-dejh8q22	249	34	sequence	sequence	NN
cord-315781-dejh8q22	249	35	alignment	alignment	NN
cord-315781-dejh8q22	249	36	with	with	IN
cord-315781-dejh8q22	249	37	high	high	JJ
cord-315781-dejh8q22	249	38	accuracy	accuracy	NN
cord-315781-dejh8q22	249	39	and	and	CC
cord-315781-dejh8q22	249	40	high	high	JJ
cord-315781-dejh8q22	249	41	throughput	throughput	NN
cord-315781-dejh8q22	249	42	R_Core_Team	r_core_team	NN
cord-315781-dejh8q22	249	43	.	.	.
cord-315781-dejh8q22	250	1	R	r	NN
cord-315781-dejh8q22	250	2	:	:	:
cord-315781-dejh8q22	251	1	A	a	DT
cord-315781-dejh8q22	251	2	language	language	NN
cord-315781-dejh8q22	251	3	and	and	CC
cord-315781-dejh8q22	251	4	environment	environment	NN
cord-315781-dejh8q22	251	5	for	for	IN
cord-315781-dejh8q22	251	6	statistical	statistical	JJ
cord-315781-dejh8q22	251	7	computing	computing	NN
cord-315781-dejh8q22	251	8	.	.	.
cord-315781-dejh8q22	252	1	(	(	-LRB-
cord-315781-dejh8q22	252	2	R	R	NNP
cord-315781-dejh8q22	252	3	Foundation	Foundation	NNP
cord-315781-dejh8q22	252	4	for	for	IN
cord-315781-dejh8q22	252	5	Statistical	Statistical	NNP
cord-315781-dejh8q22	252	6	Computing	Computing	NNP
cord-315781-dejh8q22	252	7	Principal	Principal	NNP
cord-315781-dejh8q22	252	8	component	component	NN
cord-315781-dejh8q22	252	9	analysis	analysis	NN
cord-315781-dejh8q22	252	10	for	for	IN
cord-315781-dejh8q22	252	11	designed	design	VBN
cord-315781-dejh8q22	252	12	experiments	experiment	NNS
cord-315781-dejh8q22	253	1	The	the	DT
cord-315781-dejh8q22	253	2	author	author	NN
cord-315781-dejh8q22	253	3	declares	declare	VBZ
cord-315781-dejh8q22	253	4	no	no	DT
cord-315781-dejh8q22	253	5	competing	compete	VBG
cord-315781-dejh8q22	253	6	interests	interest	NNS
cord-315781-dejh8q22	253	7	.	.	.
cord-315781-dejh8q22	254	1	Supplementary	supplementary	JJ
cord-315781-dejh8q22	254	2	information	information	NN
cord-315781-dejh8q22	254	3	is	be	VBZ
cord-315781-dejh8q22	254	4	available	available	JJ
cord-315781-dejh8q22	254	5	for	for	IN
cord-315781-dejh8q22	254	6	this	this	DT
cord-315781-dejh8q22	254	7	paper	paper	NN
cord-315781-dejh8q22	254	8	at	at	IN
cord-315781-dejh8q22	254	9	https://doi.org/10.1038/s41598-019-55254-z.Correspondence	https://doi.org/10.1038/s41598-019-55254-z.Correspondence	NNP
cord-315781-dejh8q22	254	10	and	and	CC
cord-315781-dejh8q22	254	11	requests	request	NNS
cord-315781-dejh8q22	254	12	for	for	IN
cord-315781-dejh8q22	254	13	materials	material	NNS
cord-315781-dejh8q22	254	14	should	should	MD
cord-315781-dejh8q22	254	15	be	be	VB
cord-315781-dejh8q22	254	16	addressed	address	VBN
cord-315781-dejh8q22	254	17	to	to	IN
cord-315781-dejh8q22	254	18	T.K.	T.K.	NNP
cord-315781-dejh8q22	254	19	Publisher	Publisher	NNP
cord-315781-dejh8q22	254	20	's	's	POS
cord-315781-dejh8q22	254	21	note	note	NN
cord-315781-dejh8q22	254	22	Springer	Springer	NNP
cord-315781-dejh8q22	254	23	Nature	Nature	NNP
cord-315781-dejh8q22	254	24	remains	remain	VBZ
cord-315781-dejh8q22	254	25	neutral	neutral	JJ
cord-315781-dejh8q22	254	26	with	with	IN
cord-315781-dejh8q22	254	27	regard	regard	NN
cord-315781-dejh8q22	254	28	to	to	IN
cord-315781-dejh8q22	254	29	jurisdictional	jurisdictional	JJ
cord-315781-dejh8q22	254	30	claims	claim	NNS
cord-315781-dejh8q22	254	31	in	in	IN
cord-315781-dejh8q22	254	32	published	publish	VBN
cord-315781-dejh8q22	254	33	maps	map	NNS
cord-315781-dejh8q22	254	34	and	and	CC
cord-315781-dejh8q22	254	35	institutional	institutional	JJ
cord-315781-dejh8q22	254	36	affiliations	affiliation	NNS
cord-315781-dejh8q22	254	37	.	.	.