id	sid	tid	token	lemma	pos
cord-004222-z4butywi	1	1	key	key	JJ
cord-004222-z4butywi	1	2	:	:	:
cord-004222-z4butywi	1	3	cord-004222-z4butywi	cord-004222-z4butywi	NN
cord-004222-z4butywi	1	4	authors	author	NNS
cord-004222-z4butywi	1	5	:	:	:
cord-004222-z4butywi	1	6	Joyce	Joyce	NNP
cord-004222-z4butywi	1	7	,	,	,
cord-004222-z4butywi	1	8	Collin	Collin	NNP
cord-004222-z4butywi	1	9	;	;	:
cord-004222-z4butywi	1	10	Burton	Burton	NNP
cord-004222-z4butywi	1	11	,	,	,
cord-004222-z4butywi	1	12	Dennis	Dennis	NNP
cord-004222-z4butywi	1	13	R.	R.	NNP
cord-004222-z4butywi	1	14	;	;	:
cord-004222-z4butywi	2	1	Briney	Briney	NNP
cord-004222-z4butywi	2	2	,	,	,
cord-004222-z4butywi	2	3	Bryan	Bryan	NNP
cord-004222-z4butywi	2	4	title	title	NN
cord-004222-z4butywi	2	5	:	:	:
cord-004222-z4butywi	2	6	Comparisons	comparison	NNS
cord-004222-z4butywi	2	7	of	of	IN
cord-004222-z4butywi	2	8	the	the	DT
cord-004222-z4butywi	2	9	antibody	antibody	NN
cord-004222-z4butywi	2	10	repertoires	repertoire	NNS
cord-004222-z4butywi	2	11	of	of	IN
cord-004222-z4butywi	2	12	a	a	DT
cord-004222-z4butywi	2	13	humanized	humanize	VBN
cord-004222-z4butywi	2	14	rodent	rodent	NN
cord-004222-z4butywi	2	15	and	and	CC
cord-004222-z4butywi	2	16	humans	human	NNS
cord-004222-z4butywi	2	17	by	by	IN
cord-004222-z4butywi	2	18	high	high	JJ
cord-004222-z4butywi	2	19	throughput	throughput	NN
cord-004222-z4butywi	2	20	sequencing	sequencing	NN
cord-004222-z4butywi	2	21	date	date	NN
cord-004222-z4butywi	2	22	:	:	:
cord-004222-z4butywi	2	23	2020	2020	CD
cord-004222-z4butywi	2	24	-	-	HYPH
cord-004222-z4butywi	2	25	01	01	CD
cord-004222-z4butywi	2	26	-	-	HYPH
cord-004222-z4butywi	2	27	24	24	CD
cord-004222-z4butywi	2	28	journal	journal	NN
cord-004222-z4butywi	2	29	:	:	:
cord-004222-z4butywi	3	1	Sci	Sci	NNP
cord-004222-z4butywi	3	2	Rep	Rep	NNP
cord-004222-z4butywi	3	3	DOI	DOI	NNP
cord-004222-z4butywi	3	4	:	:	:
cord-004222-z4butywi	4	1	10.1038	10.1038	CD
cord-004222-z4butywi	4	2	/	/	SYM
cord-004222-z4butywi	4	3	s41598	s41598	CD
cord-004222-z4butywi	4	4	-	-	HYPH
cord-004222-z4butywi	4	5	020	020	CD
cord-004222-z4butywi	4	6	-	-	HYPH
cord-004222-z4butywi	4	7	57764	57764	CD
cord-004222-z4butywi	4	8	-	-	SYM
cord-004222-z4butywi	4	9	7	7	CD
cord-004222-z4butywi	4	10	sha	sha	NNP
cord-004222-z4butywi	4	11	:	:	:
cord-004222-z4butywi	4	12	36ef2d1a30ab17d24e9c11bbd208ed37638cc1d5	36ef2d1a30ab17d24e9c11bbd208ed37638cc1d5	CD
cord-004222-z4butywi	4	13	doc_id	doc_id	CD
cord-004222-z4butywi	4	14	:	:	:
cord-004222-z4butywi	4	15	4222	4222	CD
cord-004222-z4butywi	4	16	cord_uid	cord_uid	NNS
cord-004222-z4butywi	4	17	:	:	:
cord-004222-z4butywi	4	18	z4butywi	z4butywi	NN
cord-004222-z4butywi	5	1	The	the	DT
cord-004222-z4butywi	5	2	humanization	humanization	NN
cord-004222-z4butywi	5	3	of	of	IN
cord-004222-z4butywi	5	4	animal	animal	NN
cord-004222-z4butywi	5	5	model	model	NN
cord-004222-z4butywi	5	6	immune	immune	JJ
cord-004222-z4butywi	5	7	systems	system	NNS
cord-004222-z4butywi	5	8	by	by	IN
cord-004222-z4butywi	5	9	genetic	genetic	JJ
cord-004222-z4butywi	5	10	engineering	engineering	NN
cord-004222-z4butywi	5	11	has	have	VBZ
cord-004222-z4butywi	5	12	shown	show	VBN
cord-004222-z4butywi	5	13	great	great	JJ
cord-004222-z4butywi	5	14	promise	promise	NN
cord-004222-z4butywi	5	15	for	for	IN
cord-004222-z4butywi	5	16	antibody	antibody	NN
cord-004222-z4butywi	5	17	discovery	discovery	NN
cord-004222-z4butywi	5	18	,	,	,
cord-004222-z4butywi	5	19	tolerance	tolerance	NN
cord-004222-z4butywi	5	20	studies	study	NNS
cord-004222-z4butywi	5	21	and	and	CC
cord-004222-z4butywi	5	22	for	for	IN
cord-004222-z4butywi	5	23	the	the	DT
cord-004222-z4butywi	5	24	evaluation	evaluation	NN
cord-004222-z4butywi	5	25	of	of	IN
cord-004222-z4butywi	5	26	vaccines	vaccine	NNS
cord-004222-z4butywi	5	27	.	.	.
cord-004222-z4butywi	6	1	Assessment	assessment	NN
cord-004222-z4butywi	6	2	of	of	IN
cord-004222-z4butywi	6	3	the	the	DT
cord-004222-z4butywi	6	4	baseline	baseline	JJ
cord-004222-z4butywi	6	5	antibody	antibody	NN
cord-004222-z4butywi	6	6	repertoires	repertoire	NNS
cord-004222-z4butywi	6	7	of	of	IN
cord-004222-z4butywi	6	8	unimmunized	unimmunized	JJ
cord-004222-z4butywi	6	9	model	model	NN
cord-004222-z4butywi	6	10	animals	animal	NNS
cord-004222-z4butywi	6	11	will	will	MD
cord-004222-z4butywi	6	12	be	be	VB
cord-004222-z4butywi	6	13	useful	useful	JJ
cord-004222-z4butywi	6	14	as	as	IN
cord-004222-z4butywi	6	15	a	a	DT
cord-004222-z4butywi	6	16	benchmark	benchmark	NN
cord-004222-z4butywi	6	17	for	for	IN
cord-004222-z4butywi	6	18	future	future	JJ
cord-004222-z4butywi	6	19	immunization	immunization	NN
cord-004222-z4butywi	6	20	experiments	experiment	NNS
cord-004222-z4butywi	6	21	.	.	.
cord-004222-z4butywi	7	1	We	-PRON-	PRP
cord-004222-z4butywi	7	2	characterized	characterize	VBD
cord-004222-z4butywi	7	3	the	the	DT
cord-004222-z4butywi	7	4	heavy	heavy	JJ
cord-004222-z4butywi	7	5	chain	chain	NN
cord-004222-z4butywi	7	6	and	and	CC
cord-004222-z4butywi	7	7	kappa	kappa	NN
cord-004222-z4butywi	7	8	light	light	NNP
cord-004222-z4butywi	7	9	chain	chain	NN
cord-004222-z4butywi	7	10	antibody	antibody	NN
cord-004222-z4butywi	7	11	repertoires	repertoire	NNS
cord-004222-z4butywi	7	12	of	of	IN
cord-004222-z4butywi	7	13	a	a	DT
cord-004222-z4butywi	7	14	model	model	NN
cord-004222-z4butywi	7	15	animal	animal	NN
cord-004222-z4butywi	7	16	,	,	,
cord-004222-z4butywi	7	17	the	the	DT
cord-004222-z4butywi	7	18	OmniRat	OmniRat	NNP
cord-004222-z4butywi	7	19	,	,	,
cord-004222-z4butywi	7	20	by	by	IN
cord-004222-z4butywi	7	21	high	high	JJ
cord-004222-z4butywi	7	22	throughput	throughput	NN
cord-004222-z4butywi	7	23	antibody	antibody	NN
cord-004222-z4butywi	7	24	sequencing	sequencing	NN
cord-004222-z4butywi	7	25	and	and	CC
cord-004222-z4butywi	7	26	made	make	VBD
cord-004222-z4butywi	7	27	use	use	NN
cord-004222-z4butywi	7	28	of	of	IN
cord-004222-z4butywi	7	29	two	two	CD
cord-004222-z4butywi	7	30	novel	novel	JJ
cord-004222-z4butywi	7	31	datasets	dataset	NNS
cord-004222-z4butywi	7	32	for	for	IN
cord-004222-z4butywi	7	33	comparison	comparison	NN
cord-004222-z4butywi	7	34	to	to	IN
cord-004222-z4butywi	7	35	human	human	JJ
cord-004222-z4butywi	7	36	repertoires	repertoire	NNS
cord-004222-z4butywi	7	37	.	.	.
cord-004222-z4butywi	8	1	Intra	intra	JJ
cord-004222-z4butywi	8	2	-	-	JJ
cord-004222-z4butywi	8	3	animal	animal	JJ
cord-004222-z4butywi	8	4	and	and	CC
cord-004222-z4butywi	8	5	inter	inter	JJ
cord-004222-z4butywi	8	6	-	-	JJ
cord-004222-z4butywi	8	7	animal	animal	JJ
cord-004222-z4butywi	8	8	repertoire	repertoire	NN
cord-004222-z4butywi	8	9	comparisons	comparison	NNS
cord-004222-z4butywi	8	10	reveal	reveal	VBP
cord-004222-z4butywi	8	11	a	a	DT
cord-004222-z4butywi	8	12	high	high	JJ
cord-004222-z4butywi	8	13	level	level	NN
cord-004222-z4butywi	8	14	of	of	IN
cord-004222-z4butywi	8	15	conservation	conservation	NN
cord-004222-z4butywi	8	16	in	in	IN
cord-004222-z4butywi	8	17	antibody	antibody	NN
cord-004222-z4butywi	8	18	diversity	diversity	NN
cord-004222-z4butywi	8	19	between	between	IN
cord-004222-z4butywi	8	20	the	the	DT
cord-004222-z4butywi	8	21	lymph	lymph	NN
cord-004222-z4butywi	8	22	node	node	NN
cord-004222-z4butywi	8	23	and	and	CC
cord-004222-z4butywi	8	24	spleen	spleen	NNS
cord-004222-z4butywi	8	25	and	and	CC
cord-004222-z4butywi	8	26	between	between	IN
cord-004222-z4butywi	8	27	members	member	NNS
cord-004222-z4butywi	8	28	of	of	IN
cord-004222-z4butywi	8	29	the	the	DT
cord-004222-z4butywi	8	30	species	specie	NNS
cord-004222-z4butywi	8	31	.	.	.
cord-004222-z4butywi	9	1	Multiple	multiple	JJ
cord-004222-z4butywi	9	2	differences	difference	NNS
cord-004222-z4butywi	9	3	were	be	VBD
cord-004222-z4butywi	9	4	found	find	VBN
cord-004222-z4butywi	9	5	in	in	IN
cord-004222-z4butywi	9	6	both	both	CC
cord-004222-z4butywi	9	7	the	the	DT
cord-004222-z4butywi	9	8	heavy	heavy	JJ
cord-004222-z4butywi	9	9	and	and	CC
cord-004222-z4butywi	9	10	kappa	kappa	NN
cord-004222-z4butywi	9	11	chain	chain	NN
cord-004222-z4butywi	9	12	repertoires	repertoire	NNS
cord-004222-z4butywi	9	13	between	between	IN
cord-004222-z4butywi	9	14	OmniRats	OmniRats	NNP
cord-004222-z4butywi	9	15	and	and	CC
cord-004222-z4butywi	9	16	humans	human	NNS
cord-004222-z4butywi	9	17	including	include	VBG
cord-004222-z4butywi	9	18	gene	gene	NN
cord-004222-z4butywi	9	19	segment	segment	NN
cord-004222-z4butywi	9	20	usage	usage	NN
cord-004222-z4butywi	9	21	,	,	,
cord-004222-z4butywi	9	22	CDR3	CDR3	NNP
cord-004222-z4butywi	9	23	length	length	NN
cord-004222-z4butywi	9	24	distributions	distribution	NNS
cord-004222-z4butywi	9	25	,	,	,
cord-004222-z4butywi	9	26	class	class	NN
cord-004222-z4butywi	9	27	switch	switch	NN
cord-004222-z4butywi	9	28	recombination	recombination	NN
cord-004222-z4butywi	9	29	,	,	,
cord-004222-z4butywi	9	30	somatic	somatic	JJ
cord-004222-z4butywi	9	31	hypermutation	hypermutation	NN
cord-004222-z4butywi	9	32	levels	level	NNS
cord-004222-z4butywi	9	33	and	and	CC
cord-004222-z4butywi	9	34	in	in	IN
cord-004222-z4butywi	9	35	features	feature	NNS
cord-004222-z4butywi	9	36	of	of	IN
cord-004222-z4butywi	9	37	V(D)J	V(D)J	NNP
cord-004222-z4butywi	9	38	recombination	recombination	NN
cord-004222-z4butywi	9	39	.	.	.
cord-004222-z4butywi	10	1	The	the	DT
cord-004222-z4butywi	10	2	Inference	Inference	NNP
cord-004222-z4butywi	10	3	and	and	CC
cord-004222-z4butywi	10	4	Generation	Generation	NNP
cord-004222-z4butywi	10	5	of	of	IN
cord-004222-z4butywi	10	6	Repertoires	Repertoires	NNPS
cord-004222-z4butywi	10	7	(	(	-LRB-
cord-004222-z4butywi	10	8	IGoR	IGoR	NNP
cord-004222-z4butywi	10	9	)	)	-RRB-
cord-004222-z4butywi	10	10	software	software	NN
cord-004222-z4butywi	10	11	tool	tool	NN
cord-004222-z4butywi	10	12	was	be	VBD
cord-004222-z4butywi	10	13	used	use	VBN
cord-004222-z4butywi	10	14	to	to	TO
cord-004222-z4butywi	10	15	model	model	VB
cord-004222-z4butywi	10	16	recombination	recombination	NN
cord-004222-z4butywi	10	17	in	in	IN
cord-004222-z4butywi	10	18	VH	VH	NNP
cord-004222-z4butywi	10	19	regions	region	NNS
cord-004222-z4butywi	10	20	which	which	WDT
cord-004222-z4butywi	10	21	allowed	allow	VBD
cord-004222-z4butywi	10	22	for	for	IN
cord-004222-z4butywi	10	23	the	the	DT
cord-004222-z4butywi	10	24	quantification	quantification	NN
cord-004222-z4butywi	10	25	of	of	IN
cord-004222-z4butywi	10	26	some	some	DT
cord-004222-z4butywi	10	27	of	of	IN
cord-004222-z4butywi	10	28	these	these	DT
cord-004222-z4butywi	10	29	differences	difference	NNS
cord-004222-z4butywi	10	30	.	.	.
cord-004222-z4butywi	11	1	Diversity	diversity	NN
cord-004222-z4butywi	11	2	estimates	estimate	NNS
cord-004222-z4butywi	11	3	of	of	IN
cord-004222-z4butywi	11	4	the	the	DT
cord-004222-z4butywi	11	5	OmniRat	OmniRat	NNP
cord-004222-z4butywi	11	6	heavy	heavy	JJ
cord-004222-z4butywi	11	7	chain	chain	NN
cord-004222-z4butywi	11	8	repertoires	repertoire	NNS
cord-004222-z4butywi	11	9	almost	almost	RB
cord-004222-z4butywi	11	10	reached	reach	VBD
cord-004222-z4butywi	11	11	that	that	DT
cord-004222-z4butywi	11	12	of	of	IN
cord-004222-z4butywi	11	13	humans	human	NNS
cord-004222-z4butywi	11	14	,	,	,
cord-004222-z4butywi	11	15	around	around	IN
cord-004222-z4butywi	11	16	two	two	CD
cord-004222-z4butywi	11	17	orders	order	NNS
cord-004222-z4butywi	11	18	of	of	IN
cord-004222-z4butywi	11	19	magnitude	magnitude	NN
cord-004222-z4butywi	11	20	less	less	JJR
cord-004222-z4butywi	11	21	.	.	.
cord-004222-z4butywi	12	1	Despite	despite	IN
cord-004222-z4butywi	12	2	variation	variation	NN
cord-004222-z4butywi	12	3	between	between	IN
cord-004222-z4butywi	12	4	the	the	DT
cord-004222-z4butywi	12	5	species	species	NN
cord-004222-z4butywi	12	6	repertoires	repertoire	NNS
cord-004222-z4butywi	12	7	,	,	,
cord-004222-z4butywi	12	8	a	a	DT
cord-004222-z4butywi	12	9	high	high	JJ
cord-004222-z4butywi	12	10	frequency	frequency	NN
cord-004222-z4butywi	12	11	of	of	IN
cord-004222-z4butywi	12	12	OmniRat	omnirat	NN
cord-004222-z4butywi	12	13	clonotypes	clonotype	NNS
cord-004222-z4butywi	12	14	were	be	VBD
cord-004222-z4butywi	12	15	also	also	RB
cord-004222-z4butywi	12	16	found	find	VBN
cord-004222-z4butywi	12	17	in	in	IN
cord-004222-z4butywi	12	18	the	the	DT
cord-004222-z4butywi	12	19	human	human	JJ
cord-004222-z4butywi	12	20	repertoire	repertoire	NN
cord-004222-z4butywi	12	21	.	.	.
cord-004222-z4butywi	13	1	These	these	DT
cord-004222-z4butywi	13	2	data	datum	NNS
cord-004222-z4butywi	13	3	give	give	VBP
cord-004222-z4butywi	13	4	insights	insight	NNS
cord-004222-z4butywi	13	5	into	into	IN
cord-004222-z4butywi	13	6	the	the	DT
cord-004222-z4butywi	13	7	development	development	NN
cord-004222-z4butywi	13	8	and	and	CC
cord-004222-z4butywi	13	9	selection	selection	NN
cord-004222-z4butywi	13	10	of	of	IN
cord-004222-z4butywi	13	11	humanized	humanized	JJ
cord-004222-z4butywi	13	12	animal	animal	NN
cord-004222-z4butywi	13	13	antibodies	antibody	NNS
cord-004222-z4butywi	13	14	and	and	CC
cord-004222-z4butywi	13	15	provide	provide	VB
cord-004222-z4butywi	13	16	actionable	actionable	JJ
cord-004222-z4butywi	13	17	information	information	NN
cord-004222-z4butywi	13	18	for	for	IN
cord-004222-z4butywi	13	19	use	use	NN
cord-004222-z4butywi	13	20	in	in	IN
cord-004222-z4butywi	13	21	vaccine	vaccine	NN
cord-004222-z4butywi	13	22	studies	study	NNS
cord-004222-z4butywi	13	23	.	.	.
cord-004222-z4butywi	14	1	RAG1	RAG1	NNP
cord-004222-z4butywi	14	2	,	,	,
cord-004222-z4butywi	14	3	RAG2	RAG2	NNP
cord-004222-z4butywi	14	4	and	and	CC
cord-004222-z4butywi	14	5	Artemis	Artemis	NNP
cord-004222-z4butywi	14	6	(	(	-LRB-
cord-004222-z4butywi	14	7	among	among	IN
cord-004222-z4butywi	14	8	others	other	NNS
cord-004222-z4butywi	14	9	)	)	-RRB-
cord-004222-z4butywi	14	10	.	.	.
cord-004222-z4butywi	15	1	P	p	NN
cord-004222-z4butywi	15	2	and	and	CC
cord-004222-z4butywi	15	3	N	n	CD
cord-004222-z4butywi	15	4	nucleotides	nucleotide	NNS
cord-004222-z4butywi	15	5	are	be	VBP
cord-004222-z4butywi	15	6	added	add	VBN
cord-004222-z4butywi	15	7	in	in	IN
cord-004222-z4butywi	15	8	the	the	DT
cord-004222-z4butywi	15	9	VH	VH	NNP
cord-004222-z4butywi	15	10	-	-	HYPH
cord-004222-z4butywi	15	11	DH	DH	NNP
cord-004222-z4butywi	15	12	and	and	CC
cord-004222-z4butywi	15	13	DH	DH	NNP
cord-004222-z4butywi	15	14	-	-	HYPH
cord-004222-z4butywi	15	15	JH	JH	NNP
cord-004222-z4butywi	15	16	junctions	junction	NNS
cord-004222-z4butywi	15	17	by	by	IN
cord-004222-z4butywi	15	18	Artemis	Artemis	NNP
cord-004222-z4butywi	15	19	and	and	CC
cord-004222-z4butywi	15	20	TdT	tdt	NN
cord-004222-z4butywi	15	21	,	,	,
cord-004222-z4butywi	15	22	dramatically	dramatically	RB
cord-004222-z4butywi	15	23	increasing	increase	VBG
cord-004222-z4butywi	15	24	sequence	sequence	NN
cord-004222-z4butywi	15	25	diversity	diversity	NN
cord-004222-z4butywi	15	26	.	.	.
cord-004222-z4butywi	16	1	After	after	IN
cord-004222-z4butywi	16	2	successful	successful	JJ
cord-004222-z4butywi	16	3	pairing	pairing	NN
cord-004222-z4butywi	16	4	of	of	IN
cord-004222-z4butywi	16	5	this	this	DT
cord-004222-z4butywi	16	6	newly	newly	RB
cord-004222-z4butywi	16	7	formed	form	VBN
cord-004222-z4butywi	16	8	heavy	heavy	JJ
cord-004222-z4butywi	16	9	chain	chain	NN
cord-004222-z4butywi	16	10	with	with	IN
cord-004222-z4butywi	16	11	surrogate	surrogate	JJ
cord-004222-z4butywi	16	12	light	light	JJ
cord-004222-z4butywi	16	13	chain	chain	NN
cord-004222-z4butywi	16	14	(	(	-LRB-
cord-004222-z4butywi	16	15	SLC	SLC	NNP
cord-004222-z4butywi	16	16	)	)	-RRB-
cord-004222-z4butywi	16	17	,	,	,
cord-004222-z4butywi	16	18	recombination	recombination	NN
cord-004222-z4butywi	16	19	of	of	IN
cord-004222-z4butywi	16	20	a	a	DT
cord-004222-z4butywi	16	21	light	light	JJ
cord-004222-z4butywi	16	22	chain	chain	NN
cord-004222-z4butywi	16	23	from	from	IN
cord-004222-z4butywi	16	24	V	V	NNP
cord-004222-z4butywi	16	25	and	and	CC
cord-004222-z4butywi	16	26	J	J	NNP
cord-004222-z4butywi	16	27	gene	gene	NN
cord-004222-z4butywi	16	28	segments	segment	NNS
cord-004222-z4butywi	16	29	of	of	IN
cord-004222-z4butywi	16	30	the	the	DT
cord-004222-z4butywi	16	31	kappa	kappa	NN
cord-004222-z4butywi	16	32	or	or	CC
cord-004222-z4butywi	16	33	lambda	lambda	NN
cord-004222-z4butywi	16	34	loci	locus	NNS
cord-004222-z4butywi	16	35	occurs	occur	VBZ
cord-004222-z4butywi	16	36	and	and	CC
cord-004222-z4butywi	16	37	the	the	DT
cord-004222-z4butywi	16	38	B	b	NN
cord-004222-z4butywi	16	39	cell	cell	NN
cord-004222-z4butywi	16	40	swaps	swap	NNS
cord-004222-z4butywi	16	41	the	the	DT
cord-004222-z4butywi	16	42	SLC	SLC	NNP
cord-004222-z4butywi	16	43	for	for	IN
cord-004222-z4butywi	16	44	this	this	DT
cord-004222-z4butywi	16	45	new	new	JJ
cord-004222-z4butywi	16	46	light	light	JJ
cord-004222-z4butywi	16	47	chain	chain	NN
cord-004222-z4butywi	16	48	.	.	.
cord-004222-z4butywi	17	1	Unless	unless	IN
cord-004222-z4butywi	17	2	the	the	DT
cord-004222-z4butywi	17	3	immature	immature	JJ
cord-004222-z4butywi	17	4	B	b	NN
cord-004222-z4butywi	17	5	cell	cell	NN
cord-004222-z4butywi	17	6	is	be	VBZ
cord-004222-z4butywi	17	7	autoreactive	autoreactive	JJ
cord-004222-z4butywi	17	8	or	or	CC
cord-004222-z4butywi	17	9	anergic	anergic	NN
cord-004222-z4butywi	17	10	and	and	CC
cord-004222-z4butywi	17	11	undergoes	undergo	VBZ
cord-004222-z4butywi	17	12	receptor	receptor	NN
cord-004222-z4butywi	17	13	editing	editing	NN
cord-004222-z4butywi	17	14	or	or	CC
cord-004222-z4butywi	17	15	clonal	clonal	JJ
cord-004222-z4butywi	17	16	deletion	deletion	NN
cord-004222-z4butywi	17	17	,	,	,
cord-004222-z4butywi	17	18	it	-PRON-	PRP
cord-004222-z4butywi	17	19	matures	mature	VBZ
cord-004222-z4butywi	17	20	into	into	IN
cord-004222-z4butywi	17	21	a	a	DT
cord-004222-z4butywi	17	22	naïve	naïve	JJ
cord-004222-z4butywi	17	23	B	b	NN
cord-004222-z4butywi	17	24	cell	cell	NN
cord-004222-z4butywi	17	25	and	and	CC
cord-004222-z4butywi	17	26	migrates	migrate	VBZ
cord-004222-z4butywi	17	27	to	to	IN
cord-004222-z4butywi	17	28	the	the	DT
cord-004222-z4butywi	17	29	periphery	periphery	NN
cord-004222-z4butywi	17	30	whereupon	whereupon	WRB
cord-004222-z4butywi	17	31	it	-PRON-	PRP
cord-004222-z4butywi	17	32	can	can	MD
cord-004222-z4butywi	17	33	become	become	VB
cord-004222-z4butywi	17	34	activated	activate	VBN
cord-004222-z4butywi	17	35	by	by	IN
cord-004222-z4butywi	17	36	encountering	encounter	VBG
cord-004222-z4butywi	17	37	antigen	antigen	NN
cord-004222-z4butywi	17	38	and	and	CC
cord-004222-z4butywi	17	39	form	form	VB
cord-004222-z4butywi	17	40	germinal	germinal	JJ
cord-004222-z4butywi	17	41	centers	center	NNS
cord-004222-z4butywi	17	42	with	with	IN
cord-004222-z4butywi	17	43	help	help	NN
cord-004222-z4butywi	17	44	from	from	IN
cord-004222-z4butywi	17	45	T	t	NN
cord-004222-z4butywi	17	46	-	-	HYPH
cord-004222-z4butywi	17	47	cells	cell	NNS
cord-004222-z4butywi	17	48	.	.	.
cord-004222-z4butywi	18	1	Sequence	sequence	NN
cord-004222-z4butywi	18	2	diversity	diversity	NN
cord-004222-z4butywi	18	3	is	be	VBZ
cord-004222-z4butywi	18	4	again	again	RB
cord-004222-z4butywi	18	5	enhanced	enhance	VBN
cord-004222-z4butywi	18	6	in	in	IN
cord-004222-z4butywi	18	7	the	the	DT
cord-004222-z4butywi	18	8	germinal	germinal	JJ
cord-004222-z4butywi	18	9	center	center	NN
cord-004222-z4butywi	18	10	by	by	IN
cord-004222-z4butywi	18	11	somatic	somatic	JJ
cord-004222-z4butywi	18	12	hypermutation	hypermutation	NN
cord-004222-z4butywi	18	13	(	(	-LRB-
cord-004222-z4butywi	18	14	SHM	SHM	NNP
cord-004222-z4butywi	18	15	)	)	-RRB-
cord-004222-z4butywi	18	16	and/or	and/or	CC
cord-004222-z4butywi	18	17	class	class	NN
cord-004222-z4butywi	18	18	switch	switch	NN
cord-004222-z4butywi	18	19	recombination	recombination	NN
cord-004222-z4butywi	18	20	(	(	-LRB-
cord-004222-z4butywi	18	21	CSR	CSR	NNP
cord-004222-z4butywi	18	22	)	)	-RRB-
cord-004222-z4butywi	18	23	,	,	,
cord-004222-z4butywi	18	24	two	two	CD
cord-004222-z4butywi	18	25	processes	process	NNS
cord-004222-z4butywi	18	26	that	that	WDT
cord-004222-z4butywi	18	27	depend	depend	VBP
cord-004222-z4butywi	18	28	on	on	IN
cord-004222-z4butywi	18	29	activation	activation	NN
cord-004222-z4butywi	18	30	induced	induce	VBN
cord-004222-z4butywi	18	31	cytidine	cytidine	NNP
cord-004222-z4butywi	18	32	deaminase	deaminase	NNP
cord-004222-z4butywi	18	33	(	(	-LRB-
cord-004222-z4butywi	18	34	AID	aid	NN
cord-004222-z4butywi	18	35	)	)	-RRB-
cord-004222-z4butywi	18	36	.	.	.
cord-004222-z4butywi	19	1	The	the	DT
cord-004222-z4butywi	19	2	OmniRat	OmniRat	NNP
cord-004222-z4butywi	19	3	was	be	VBD
cord-004222-z4butywi	19	4	created	create	VBN
cord-004222-z4butywi	19	5	by	by	IN
cord-004222-z4butywi	19	6	genomic	genomic	JJ
cord-004222-z4butywi	19	7	integration	integration	NN
cord-004222-z4butywi	19	8	of	of	IN
cord-004222-z4butywi	19	9	human	human	JJ
cord-004222-z4butywi	19	10	immunoglobulin	immunoglobulin	NN
cord-004222-z4butywi	19	11	(	(	-LRB-
cord-004222-z4butywi	19	12	Ig	Ig	NNP
cord-004222-z4butywi	19	13	)	)	-RRB-
cord-004222-z4butywi	19	14	loci	locus	NNS
cord-004222-z4butywi	19	15	on	on	IN
cord-004222-z4butywi	19	16	a	a	DT
cord-004222-z4butywi	19	17	background	background	NN
cord-004222-z4butywi	19	18	of	of	IN
cord-004222-z4butywi	19	19	inactivated	inactivate	VBN
cord-004222-z4butywi	19	20	endogenous	endogenous	JJ
cord-004222-z4butywi	19	21	rat	rat	NN
cord-004222-z4butywi	19	22	Ig	ig	NN
cord-004222-z4butywi	19	23	loci	locus	NNS
cord-004222-z4butywi	19	24	.	.	.
cord-004222-z4butywi	20	1	It	-PRON-	PRP
cord-004222-z4butywi	20	2	expresses	express	VBZ
cord-004222-z4butywi	20	3	chimeric	chimeric	JJ
cord-004222-z4butywi	20	4	heavy	heavy	JJ
cord-004222-z4butywi	20	5	chains	chain	NNS
cord-004222-z4butywi	20	6	(	(	-LRB-
cord-004222-z4butywi	20	7	i.e.	i.e.	FW
cord-004222-z4butywi	20	8	human	human	JJ
cord-004222-z4butywi	20	9	V	V	NNP
cord-004222-z4butywi	20	10	,	,	,
cord-004222-z4butywi	20	11	D	D	NNP
cord-004222-z4butywi	20	12	,	,	,
cord-004222-z4butywi	20	13	and	and	CC
cord-004222-z4butywi	20	14	J	J	NNP
cord-004222-z4butywi	20	15	genes	gene	NNS
cord-004222-z4butywi	20	16	and	and	CC
cord-004222-z4butywi	20	17	rat	rat	NN
cord-004222-z4butywi	20	18	constant	constant	JJ
cord-004222-z4butywi	20	19	genes	gene	NNS
cord-004222-z4butywi	20	20	)	)	-RRB-
cord-004222-z4butywi	20	21	that	that	WDT
cord-004222-z4butywi	20	22	pair	pair	VBP
cord-004222-z4butywi	20	23	with	with	IN
cord-004222-z4butywi	20	24	fully	fully	RB
cord-004222-z4butywi	20	25	human	human	JJ
cord-004222-z4butywi	20	26	light	light	NN
cord-004222-z4butywi	20	27	chains	chain	NNS
cord-004222-z4butywi	20	28	11	11	CD
cord-004222-z4butywi	20	29	,	,	,
cord-004222-z4butywi	20	30	12	12	CD
cord-004222-z4butywi	20	31	.	.	.
cord-004222-z4butywi	21	1	We	-PRON-	PRP
cord-004222-z4butywi	21	2	sought	seek	VBD
cord-004222-z4butywi	21	3	to	to	TO
cord-004222-z4butywi	21	4	characterize	characterize	VB
cord-004222-z4butywi	21	5	the	the	DT
cord-004222-z4butywi	21	6	circulating	circulate	VBG
cord-004222-z4butywi	21	7	antibody	antibody	NN
cord-004222-z4butywi	21	8	repertoire	repertoire	NN
cord-004222-z4butywi	21	9	diversity	diversity	NN
cord-004222-z4butywi	21	10	in	in	IN
cord-004222-z4butywi	21	11	this	this	DT
cord-004222-z4butywi	21	12	animal	animal	NN
cord-004222-z4butywi	21	13	and	and	CC
cord-004222-z4butywi	21	14	make	make	VB
cord-004222-z4butywi	21	15	comparisons	comparison	NNS
cord-004222-z4butywi	21	16	to	to	IN
cord-004222-z4butywi	21	17	humans	human	NNS
cord-004222-z4butywi	21	18	.	.	.
cord-004222-z4butywi	22	1	High	high	JJ
cord-004222-z4butywi	22	2	throughput	throughput	NN
cord-004222-z4butywi	22	3	antibody	antibody	NN
cord-004222-z4butywi	22	4	sequencing	sequencing	NN
cord-004222-z4butywi	22	5	has	have	VBZ
cord-004222-z4butywi	22	6	been	be	VBN
cord-004222-z4butywi	22	7	used	use	VBN
cord-004222-z4butywi	22	8	to	to	TO
cord-004222-z4butywi	22	9	describe	describe	VB
cord-004222-z4butywi	22	10	the	the	DT
cord-004222-z4butywi	22	11	circulating	circulate	VBG
cord-004222-z4butywi	22	12	antibody	antibody	NN
cord-004222-z4butywi	22	13	repertoire	repertoire	NN
cord-004222-z4butywi	22	14	of	of	IN
cord-004222-z4butywi	22	15	organisms	organism	NNS
cord-004222-z4butywi	22	16	,	,	,
cord-004222-z4butywi	22	17	including	include	VBG
cord-004222-z4butywi	22	18	more	more	RBR
cord-004222-z4butywi	22	19	recently	recently	RB
cord-004222-z4butywi	22	20	at	at	IN
cord-004222-z4butywi	22	21	unprecedented	unprecedented	JJ
cord-004222-z4butywi	22	22	depth	depth	NN
cord-004222-z4butywi	22	23	in	in	IN
cord-004222-z4butywi	22	24	humans	human	NNS
cord-004222-z4butywi	22	25	13	13	CD
cord-004222-z4butywi	22	26	.	.	.
cord-004222-z4butywi	23	1	Reverse	reverse	JJ
cord-004222-z4butywi	23	2	transcription	transcription	NN
cord-004222-z4butywi	23	3	of	of	IN
cord-004222-z4butywi	23	4	antibody	antibody	NN
cord-004222-z4butywi	23	5	RNA	RNA	NNP
cord-004222-z4butywi	23	6	and	and	CC
cord-004222-z4butywi	23	7	combined	combine	VBN
cord-004222-z4butywi	23	8	tagging	tagging	NN
cord-004222-z4butywi	23	9	with	with	IN
cord-004222-z4butywi	23	10	unique	unique	JJ
cord-004222-z4butywi	23	11	molecular	molecular	JJ
cord-004222-z4butywi	23	12	identifiers	identifier	NNS
cord-004222-z4butywi	23	13	(	(	-LRB-
cord-004222-z4butywi	23	14	UMIs	umi	NNS
cord-004222-z4butywi	23	15	)	)	-RRB-
cord-004222-z4butywi	23	16	have	have	VBP
cord-004222-z4butywi	23	17	allowed	allow	VBN
cord-004222-z4butywi	23	18	us	-PRON-	PRP
cord-004222-z4butywi	23	19	14	14	CD
cord-004222-z4butywi	23	20	and	and	CC
cord-004222-z4butywi	23	21	others	other	NNS
cord-004222-z4butywi	23	22	15	15	CD
cord-004222-z4butywi	23	23	,	,	,
cord-004222-z4butywi	23	24	16	16	CD
cord-004222-z4butywi	23	25	to	to	TO
cord-004222-z4butywi	23	26	correct	correct	VB
cord-004222-z4butywi	23	27	for	for	IN
cord-004222-z4butywi	23	28	error	error	NN
cord-004222-z4butywi	23	29	and	and	CC
cord-004222-z4butywi	23	30	bias	bias	NN
cord-004222-z4butywi	23	31	in	in	IN
cord-004222-z4butywi	23	32	antibody	antibody	NN
cord-004222-z4butywi	23	33	sequencing	sequencing	NN
cord-004222-z4butywi	23	34	.	.	.
cord-004222-z4butywi	24	1	Using	use	VBG
cord-004222-z4butywi	24	2	these	these	DT
cord-004222-z4butywi	24	3	methods	method	NNS
cord-004222-z4butywi	24	4	to	to	TO
cord-004222-z4butywi	24	5	gain	gain	VB
cord-004222-z4butywi	24	6	insight	insight	NN
cord-004222-z4butywi	24	7	into	into	IN
cord-004222-z4butywi	24	8	the	the	DT
cord-004222-z4butywi	24	9	antibody	antibody	NN
cord-004222-z4butywi	24	10	repertoire	repertoire	NN
cord-004222-z4butywi	24	11	of	of	IN
cord-004222-z4butywi	24	12	OmniRats	OmniRats	NNP
cord-004222-z4butywi	24	13	,	,	,
cord-004222-z4butywi	24	14	we	-PRON-	PRP
cord-004222-z4butywi	24	15	ask	ask	VBP
cord-004222-z4butywi	24	16	whether	whether	IN
cord-004222-z4butywi	24	17	or	or	CC
cord-004222-z4butywi	24	18	not	not	RB
cord-004222-z4butywi	24	19	it	-PRON-	PRP
cord-004222-z4butywi	24	20	accurately	accurately	RB
cord-004222-z4butywi	24	21	represents	represent	VBZ
cord-004222-z4butywi	24	22	that	that	DT
cord-004222-z4butywi	24	23	of	of	IN
cord-004222-z4butywi	24	24	humans	human	NNS
cord-004222-z4butywi	24	25	,	,	,
cord-004222-z4butywi	24	26	and	and	CC
cord-004222-z4butywi	24	27	by	by	IN
cord-004222-z4butywi	24	28	extension	extension	NN
cord-004222-z4butywi	24	29	allows	allow	VBZ
cord-004222-z4butywi	24	30	for	for	IN
cord-004222-z4butywi	24	31	usefulness	usefulness	NN
cord-004222-z4butywi	24	32	in	in	IN
cord-004222-z4butywi	24	33	the	the	DT
cord-004222-z4butywi	24	34	approximation	approximation	NN
cord-004222-z4butywi	24	35	of	of	IN
cord-004222-z4butywi	24	36	the	the	DT
cord-004222-z4butywi	24	37	human	human	JJ
cord-004222-z4butywi	24	38	antibody	antibody	NN
cord-004222-z4butywi	24	39	response	response	NN
cord-004222-z4butywi	24	40	.	.	.
cord-004222-z4butywi	25	1	We	-PRON-	PRP
cord-004222-z4butywi	25	2	postulate	postulate	VBP
cord-004222-z4butywi	25	3	that	that	IN
cord-004222-z4butywi	25	4	there	there	EX
cord-004222-z4butywi	25	5	are	be	VBP
cord-004222-z4butywi	25	6	major	major	JJ
cord-004222-z4butywi	25	7	differences	difference	NNS
cord-004222-z4butywi	25	8	in	in	IN
cord-004222-z4butywi	25	9	the	the	DT
cord-004222-z4butywi	25	10	repertoires	repertoire	NNS
cord-004222-z4butywi	25	11	due	due	JJ
cord-004222-z4butywi	25	12	to	to	IN
cord-004222-z4butywi	25	13	distinctness	distinctness	NN
cord-004222-z4butywi	25	14	in	in	IN
cord-004222-z4butywi	25	15	the	the	DT
cord-004222-z4butywi	25	16	Ig	Ig	NNP
cord-004222-z4butywi	25	17	loci	locus	NNS
cord-004222-z4butywi	25	18	genomic	genomic	JJ
cord-004222-z4butywi	25	19	structure	structure	NN
cord-004222-z4butywi	25	20	and	and	CC
cord-004222-z4butywi	25	21	genes	gene	NNS
cord-004222-z4butywi	25	22	that	that	WDT
cord-004222-z4butywi	25	23	shape	shape	VBP
cord-004222-z4butywi	25	24	antibody	antibody	NN
cord-004222-z4butywi	25	25	diversity	diversity	NN
cord-004222-z4butywi	25	26	between	between	IN
cord-004222-z4butywi	25	27	species	specie	NNS
cord-004222-z4butywi	25	28	.	.	.
cord-004222-z4butywi	26	1	Here	here	RB
cord-004222-z4butywi	26	2	,	,	,
cord-004222-z4butywi	26	3	we	-PRON-	PRP
cord-004222-z4butywi	26	4	provide	provide	VBP
cord-004222-z4butywi	26	5	the	the	DT
cord-004222-z4butywi	26	6	most	most	RBS
cord-004222-z4butywi	26	7	thorough	thorough	JJ
cord-004222-z4butywi	26	8	description	description	NN
cord-004222-z4butywi	26	9	of	of	IN
cord-004222-z4butywi	26	10	humanized	humanized	JJ
cord-004222-z4butywi	26	11	transgenic	transgenic	JJ
cord-004222-z4butywi	26	12	rodent	rodent	NN
cord-004222-z4butywi	26	13	antibody	antibody	NN
cord-004222-z4butywi	26	14	repertoires	repertoire	NNS
cord-004222-z4butywi	26	15	to	to	IN
cord-004222-z4butywi	26	16	date	date	NN
cord-004222-z4butywi	26	17	and	and	CC
cord-004222-z4butywi	26	18	leverage	leverage	VB
cord-004222-z4butywi	26	19	a	a	DT
cord-004222-z4butywi	26	20	novel	novel	NN
cord-004222-z4butywi	26	21	extremely	extremely	RB
cord-004222-z4butywi	26	22	deep	deep	JJ
cord-004222-z4butywi	26	23	human	human	JJ
cord-004222-z4butywi	26	24	dataset	dataset	NN
cord-004222-z4butywi	26	25	to	to	TO
cord-004222-z4butywi	26	26	make	make	VB
cord-004222-z4butywi	26	27	comparisons	comparison	NNS
cord-004222-z4butywi	26	28	with	with	IN
cord-004222-z4butywi	26	29	implications	implication	NNS
cord-004222-z4butywi	26	30	of	of	IN
cord-004222-z4butywi	26	31	immediate	immediate	JJ
cord-004222-z4butywi	26	32	use	use	NN
cord-004222-z4butywi	26	33	as	as	IN
cord-004222-z4butywi	26	34	a	a	DT
cord-004222-z4butywi	26	35	reference	reference	NN
cord-004222-z4butywi	26	36	for	for	IN
cord-004222-z4butywi	26	37	OmniRat	OmniRat	NNP
cord-004222-z4butywi	26	38	immunization	immunization	NN
cord-004222-z4butywi	26	39	studies	study	NNS
cord-004222-z4butywi	26	40	.	.	.
cord-004222-z4butywi	27	1	We	-PRON-	PRP
cord-004222-z4butywi	27	2	individually	individually	RB
cord-004222-z4butywi	27	3	separated	separate	VBD
cord-004222-z4butywi	27	4	total	total	JJ
cord-004222-z4butywi	27	5	RNA	RNA	NNP
cord-004222-z4butywi	27	6	from	from	IN
cord-004222-z4butywi	27	7	spleens	spleen	NNS
cord-004222-z4butywi	27	8	and	and	CC
cord-004222-z4butywi	27	9	lymph	lymph	NN
cord-004222-z4butywi	27	10	nodes	node	NNS
cord-004222-z4butywi	27	11	of	of	IN
cord-004222-z4butywi	27	12	three	three	CD
cord-004222-z4butywi	27	13	unimmunized	unimmunized	JJ
cord-004222-z4butywi	27	14	OmniRats	OmniRats	NNP
cord-004222-z4butywi	27	15	and	and	CC
cord-004222-z4butywi	27	16	PCR	PCR	NNP
cord-004222-z4butywi	27	17	amplified	amplify	VBD
cord-004222-z4butywi	27	18	the	the	DT
cord-004222-z4butywi	27	19	heavy	heavy	JJ
cord-004222-z4butywi	27	20	and	and	CC
cord-004222-z4butywi	27	21	kappa	kappa	NN
cord-004222-z4butywi	27	22	chain	chain	NN
cord-004222-z4butywi	27	23	antibody	antibody	NN
cord-004222-z4butywi	27	24	V	v	NN
cord-004222-z4butywi	27	25	gene	gene	NN
cord-004222-z4butywi	27	26	segments	segment	NNS
cord-004222-z4butywi	27	27	.	.	.
cord-004222-z4butywi	28	1	The	the	DT
cord-004222-z4butywi	28	2	resulting	result	VBG
cord-004222-z4butywi	28	3	amplicons	amplicon	NNS
cord-004222-z4butywi	28	4	were	be	VBD
cord-004222-z4butywi	28	5	subjected	subject	VBN
cord-004222-z4butywi	28	6	to	to	IN
cord-004222-z4butywi	28	7	high	high	JJ
cord-004222-z4butywi	28	8	throughput	throughput	NN
cord-004222-z4butywi	28	9	sequencing	sequencing	NN
cord-004222-z4butywi	28	10	in	in	IN
cord-004222-z4butywi	28	11	conjunction	conjunction	NN
cord-004222-z4butywi	28	12	with	with	IN
cord-004222-z4butywi	28	13	preprocessing	preprocessing	NN
cord-004222-z4butywi	28	14	and	and	CC
cord-004222-z4butywi	28	15	annotation	annotation	NN
cord-004222-z4butywi	28	16	by	by	IN
cord-004222-z4butywi	28	17	the	the	DT
cord-004222-z4butywi	28	18	Abstar	Abstar	NNP
cord-004222-z4butywi	28	19	analysis	analysis	NN
cord-004222-z4butywi	28	20	pipeline	pipeline	NN
cord-004222-z4butywi	28	21	17	17	CD
cord-004222-z4butywi	28	22	(	(	-LRB-
cord-004222-z4butywi	28	23	Methods	method	NNS
cord-004222-z4butywi	28	24	)	)	-RRB-
cord-004222-z4butywi	28	25	which	which	WDT
cord-004222-z4butywi	28	26	resulted	result	VBD
cord-004222-z4butywi	28	27	in	in	IN
cord-004222-z4butywi	28	28	a	a	DT
cord-004222-z4butywi	28	29	mean	mean	NN
cord-004222-z4butywi	28	30	of	of	IN
cord-004222-z4butywi	28	31	~3	~3	NFP
cord-004222-z4butywi	28	32	×	×	NN
cord-004222-z4butywi	28	33	10	10	CD
cord-004222-z4butywi	28	34	6	6	CD
cord-004222-z4butywi	28	35	processed	process	VBN
cord-004222-z4butywi	28	36	heavy	heavy	JJ
cord-004222-z4butywi	28	37	chain	chain	NN
cord-004222-z4butywi	28	38	sequences	sequence	NNS
cord-004222-z4butywi	28	39	and	and	CC
cord-004222-z4butywi	29	1	~1.5	~1.5	CD
cord-004222-z4butywi	29	2	×	×	NN
cord-004222-z4butywi	29	3	10	10	CD
cord-004222-z4butywi	29	4	6	6	CD
cord-004222-z4butywi	29	5	processed	process	VBN
cord-004222-z4butywi	29	6	kappa	kappa	NN
cord-004222-z4butywi	29	7	chain	chain	NN
cord-004222-z4butywi	29	8	sequences	sequence	NNS
cord-004222-z4butywi	29	9	per	per	IN
cord-004222-z4butywi	29	10	transgenic	transgenic	JJ
cord-004222-z4butywi	29	11	animal	animal	NN
cord-004222-z4butywi	29	12	(	(	-LRB-
cord-004222-z4butywi	29	13	Table	Table	NNP
cord-004222-z4butywi	29	14	S1	S1	NNP
cord-004222-z4butywi	29	15	)	)	-RRB-
cord-004222-z4butywi	29	16	.	.	.
cord-004222-z4butywi	30	1	Two	two	CD
cord-004222-z4butywi	30	2	previously	previously	RB
cord-004222-z4butywi	30	3	published	publish	VBN
cord-004222-z4butywi	30	4	datasets	dataset	NNS
cord-004222-z4butywi	30	5	13,18	13,18	CD
cord-004222-z4butywi	30	6	of	of	IN
cord-004222-z4butywi	30	7	the	the	DT
cord-004222-z4butywi	30	8	same	same	JJ
cord-004222-z4butywi	30	9	10	10	CD
cord-004222-z4butywi	30	10	humans	human	NNS
cord-004222-z4butywi	30	11	which	which	WDT
cord-004222-z4butywi	30	12	together	together	RB
cord-004222-z4butywi	30	13	contain	contain	VBP
cord-004222-z4butywi	30	14	a	a	DT
cord-004222-z4butywi	30	15	mean	mean	NN
cord-004222-z4butywi	30	16	of	of	IN
cord-004222-z4butywi	30	17	~3.6	~3.6	CD
cord-004222-z4butywi	30	18	×	×	NN
cord-004222-z4butywi	30	19	10	10	CD
cord-004222-z4butywi	30	20	7	7	CD
cord-004222-z4butywi	30	21	processed	process	VBN
cord-004222-z4butywi	30	22	heavy	heavy	JJ
cord-004222-z4butywi	30	23	chain	chain	NN
cord-004222-z4butywi	30	24	sequences	sequence	NNS
cord-004222-z4butywi	30	25	and	and	CC
cord-004222-z4butywi	30	26	~1.5	~1.5	CD
cord-004222-z4butywi	30	27	×	×	NN
cord-004222-z4butywi	30	28	10	10	CD
cord-004222-z4butywi	30	29	6	6	CD
cord-004222-z4butywi	30	30	processed	process	VBN
cord-004222-z4butywi	30	31	kappa	kappa	NN
cord-004222-z4butywi	30	32	chain	chain	NN
cord-004222-z4butywi	30	33	sequences	sequence	NNS
cord-004222-z4butywi	30	34	per	per	IN
cord-004222-z4butywi	30	35	individual	individual	NN
cord-004222-z4butywi	30	36	were	be	VBD
cord-004222-z4butywi	30	37	used	use	VBN
cord-004222-z4butywi	30	38	for	for	IN
cord-004222-z4butywi	30	39	comparison	comparison	NN
cord-004222-z4butywi	30	40	.	.	.
cord-004222-z4butywi	31	1	We	-PRON-	PRP
cord-004222-z4butywi	31	2	started	start	VBD
cord-004222-z4butywi	31	3	by	by	IN
cord-004222-z4butywi	31	4	making	make	VBG
cord-004222-z4butywi	31	5	intra	intra	JJ
cord-004222-z4butywi	31	6	-	-	JJ
cord-004222-z4butywi	31	7	animal	animal	JJ
cord-004222-z4butywi	31	8	comparisons	comparison	NNS
cord-004222-z4butywi	31	9	,	,	,
cord-004222-z4butywi	31	10	intra	intra	JJ
cord-004222-z4butywi	31	11	-	-	JJ
cord-004222-z4butywi	31	12	species	species	JJ
cord-004222-z4butywi	31	13	comparisons	comparison	NNS
cord-004222-z4butywi	31	14	and	and	CC
cord-004222-z4butywi	31	15	inter	inter	JJ
cord-004222-z4butywi	31	16	-	-	JJ
cord-004222-z4butywi	31	17	species	species	JJ
cord-004222-z4butywi	31	18	comparisons	comparison	NNS
cord-004222-z4butywi	31	19	of	of	IN
cord-004222-z4butywi	31	20	the	the	DT
cord-004222-z4butywi	31	21	immunoglobulin	immunoglobulin	NN
cord-004222-z4butywi	31	22	gene	gene	NN
cord-004222-z4butywi	31	23	segment	segment	NN
cord-004222-z4butywi	31	24	usage	usage	NN
cord-004222-z4butywi	31	25	frequencies	frequency	NNS
cord-004222-z4butywi	31	26	for	for	IN
cord-004222-z4butywi	31	27	each	each	DT
cord-004222-z4butywi	31	28	antibody	antibody	NN
cord-004222-z4butywi	31	29	repertoire	repertoire	NN
cord-004222-z4butywi	31	30	by	by	IN
cord-004222-z4butywi	31	31	performing	perform	VBG
cord-004222-z4butywi	31	32	hierarchical	hierarchical	JJ
cord-004222-z4butywi	31	33	clustering	clustering	NN
cord-004222-z4butywi	31	34	(	(	-LRB-
cord-004222-z4butywi	31	35	Fig	Fig	NNP
cord-004222-z4butywi	31	36	.	.	.
cord-004222-z4butywi	31	37	1	1	CD
cord-004222-z4butywi	31	38	)	)	-RRB-
cord-004222-z4butywi	31	39	and	and	CC
cord-004222-z4butywi	31	40	linear	linear	JJ
cord-004222-z4butywi	31	41	regression	regression	NN
cord-004222-z4butywi	31	42	analysis	analysis	NN
cord-004222-z4butywi	31	43	(	(	-LRB-
cord-004222-z4butywi	31	44	Figs	Figs	NNP
cord-004222-z4butywi	31	45	.	.	.
cord-004222-z4butywi	31	46	S1	S1	NNP
cord-004222-z4butywi	31	47	and	and	CC
cord-004222-z4butywi	31	48	S2	S2	NNP
cord-004222-z4butywi	31	49	)	)	-RRB-
cord-004222-z4butywi	31	50	.	.	.
cord-004222-z4butywi	32	1	Repertoires	repertoire	NNS
cord-004222-z4butywi	32	2	were	be	VBD
cord-004222-z4butywi	32	3	found	find	VBN
cord-004222-z4butywi	32	4	to	to	TO
cord-004222-z4butywi	32	5	cluster	cluster	NN
cord-004222-z4butywi	32	6	by	by	IN
cord-004222-z4butywi	32	7	species	specie	NNS
cord-004222-z4butywi	32	8	and	and	CC
cord-004222-z4butywi	32	9	tissue	tissue	NN
cord-004222-z4butywi	32	10	when	when	WRB
cord-004222-z4butywi	32	11	variable	variable	JJ
cord-004222-z4butywi	32	12	heavy	heavy	JJ
cord-004222-z4butywi	32	13	(	(	-LRB-
cord-004222-z4butywi	32	14	VH	VH	NNP
cord-004222-z4butywi	32	15	)	)	-RRB-
cord-004222-z4butywi	32	16	(	(	-LRB-
cord-004222-z4butywi	32	17	Fig	Fig	NNP
cord-004222-z4butywi	32	18	.	.	.
cord-004222-z4butywi	32	19	1a	1a	CD
cord-004222-z4butywi	32	20	)	)	-RRB-
cord-004222-z4butywi	32	21	,	,	,
cord-004222-z4butywi	32	22	diversity	diversity	NN
cord-004222-z4butywi	32	23	heavy	heavy	JJ
cord-004222-z4butywi	32	24	(	(	-LRB-
cord-004222-z4butywi	32	25	DH	dh	NN
cord-004222-z4butywi	32	26	)	)	-RRB-
cord-004222-z4butywi	32	27	(	(	-LRB-
cord-004222-z4butywi	32	28	Fig	Fig	NNP
cord-004222-z4butywi	32	29	.	.	.
cord-004222-z4butywi	32	30	1b	1b	CD
cord-004222-z4butywi	32	31	)	)	-RRB-
cord-004222-z4butywi	32	32	,	,	,
cord-004222-z4butywi	32	33	joining	join	VBG
cord-004222-z4butywi	32	34	heavy	heavy	JJ
cord-004222-z4butywi	32	35	(	(	-LRB-
cord-004222-z4butywi	32	36	JH	JH	NNP
cord-004222-z4butywi	32	37	)	)	-RRB-
cord-004222-z4butywi	32	38	(	(	-LRB-
cord-004222-z4butywi	32	39	Fig	Fig	NNP
cord-004222-z4butywi	32	40	.	.	.
cord-004222-z4butywi	32	41	1c	1c	NNP
cord-004222-z4butywi	32	42	)	)	-RRB-
cord-004222-z4butywi	32	43	and	and	CC
cord-004222-z4butywi	32	44	variable	variable	JJ
cord-004222-z4butywi	32	45	kappa	kappa	NN
cord-004222-z4butywi	32	46	(	(	-LRB-
cord-004222-z4butywi	32	47	VK	VK	NNP
cord-004222-z4butywi	32	48	)	)	-RRB-
cord-004222-z4butywi	33	1	(	(	-LRB-
cord-004222-z4butywi	33	2	Fig	Fig	NNP
cord-004222-z4butywi	33	3	.	.	.
cord-004222-z4butywi	33	4	S5a	s5a	JJ
cord-004222-z4butywi	33	5	)	)	-RRB-
cord-004222-z4butywi	33	6	,	,	,
cord-004222-z4butywi	33	7	but	but	CC
cord-004222-z4butywi	33	8	not	not	RB
cord-004222-z4butywi	33	9	joining	join	VBG
cord-004222-z4butywi	33	10	kappa	kappa	NNP
cord-004222-z4butywi	33	11	(	(	-LRB-
cord-004222-z4butywi	33	12	JK	JK	NNP
cord-004222-z4butywi	33	13	)	)	-RRB-
cord-004222-z4butywi	34	1	(	(	-LRB-
cord-004222-z4butywi	34	2	Fig	Fig	NNP
cord-004222-z4butywi	34	3	.	.	.
cord-004222-z4butywi	34	4	S5b	s5b	NN
cord-004222-z4butywi	34	5	)	)	-RRB-
cord-004222-z4butywi	35	1	gene	gene	NN
cord-004222-z4butywi	35	2	usage	usage	NN
cord-004222-z4butywi	35	3	was	be	VBD
cord-004222-z4butywi	35	4	examined	examine	VBN
cord-004222-z4butywi	35	5	.	.	.
cord-004222-z4butywi	36	1	Differences	difference	NNS
cord-004222-z4butywi	36	2	between	between	IN
cord-004222-z4butywi	36	3	the	the	DT
cord-004222-z4butywi	36	4	lymph	lymph	NN
cord-004222-z4butywi	36	5	node	node	NN
cord-004222-z4butywi	36	6	and	and	CC
cord-004222-z4butywi	36	7	spleens	spleen	NNS
cord-004222-z4butywi	36	8	of	of	IN
cord-004222-z4butywi	36	9	individual	individual	JJ
cord-004222-z4butywi	36	10	OmniRats	OmniRats	NNP
cord-004222-z4butywi	36	11	were	be	VBD
cord-004222-z4butywi	36	12	next	next	RB
cord-004222-z4butywi	36	13	investigated	investigate	VBN
cord-004222-z4butywi	36	14	.	.	.
cord-004222-z4butywi	37	1	VH	VH	NNP
cord-004222-z4butywi	37	2	gene	gene	NN
cord-004222-z4butywi	37	3	,	,	,
cord-004222-z4butywi	37	4	DH	DH	NNP
cord-004222-z4butywi	37	5	gene	gene	NN
cord-004222-z4butywi	37	6	and	and	CC
cord-004222-z4butywi	37	7	JH	JH	NNP
cord-004222-z4butywi	37	8	gene	gene	NN
cord-004222-z4butywi	37	9	usage	usage	NN
cord-004222-z4butywi	37	10	frequencies	frequency	NNS
cord-004222-z4butywi	37	11	between	between	IN
cord-004222-z4butywi	37	12	these	these	DT
cord-004222-z4butywi	37	13	tissues	tissue	NNS
cord-004222-z4butywi	37	14	were	be	VBD
cord-004222-z4butywi	37	15	highly	highly	RB
cord-004222-z4butywi	37	16	correlated	correlate	VBN
cord-004222-z4butywi	38	1	(	(	-LRB-
cord-004222-z4butywi	38	2	Fig	Fig	NNP
cord-004222-z4butywi	38	3	.	.	.
cord-004222-z4butywi	38	4	S1	S1	NNP
cord-004222-z4butywi	38	5	)	)	-RRB-
cord-004222-z4butywi	38	6	,	,	,
cord-004222-z4butywi	38	7	although	although	IN
cord-004222-z4butywi	38	8	a	a	DT
cord-004222-z4butywi	38	9	few	few	JJ
cord-004222-z4butywi	38	10	VH	VH	NNP
cord-004222-z4butywi	38	11	gene	gene	NN
cord-004222-z4butywi	38	12	segments	segment	NNS
cord-004222-z4butywi	38	13	were	be	VBD
cord-004222-z4butywi	38	14	overrepresented	overrepresente	VBN
cord-004222-z4butywi	38	15	in	in	IN
cord-004222-z4butywi	38	16	spleen	spleen	NNS
cord-004222-z4butywi	38	17	as	as	IN
cord-004222-z4butywi	38	18	compared	compare	VBN
cord-004222-z4butywi	38	19	to	to	IN
cord-004222-z4butywi	38	20	lymph	lymph	NN
cord-004222-z4butywi	38	21	nodes	node	NNS
cord-004222-z4butywi	38	22	including	include	VBG
cord-004222-z4butywi	38	23	VH4	VH4	NNP
cord-004222-z4butywi	38	24	-	-	HYPH
cord-004222-z4butywi	38	25	34	34	CD
cord-004222-z4butywi	38	26	,	,	,
cord-004222-z4butywi	38	27	VH4	VH4	NNP
cord-004222-z4butywi	38	28	-	-	HYPH
cord-004222-z4butywi	38	29	59	59	CD
cord-004222-z4butywi	38	30	and	and	CC
cord-004222-z4butywi	38	31	VH5	VH5	NNP
cord-004222-z4butywi	38	32	-	-	HYPH
cord-004222-z4butywi	38	33	1	1	CD
cord-004222-z4butywi	38	34	(	(	-LRB-
cord-004222-z4butywi	38	35	Figs	Figs	NNP
cord-004222-z4butywi	38	36	.	.	.
cord-004222-z4butywi	38	37	1a	1a	CD
cord-004222-z4butywi	38	38	and	and	CC
cord-004222-z4butywi	38	39	S3a	s3a	ADD
cord-004222-z4butywi	38	40	)	)	-RRB-
cord-004222-z4butywi	38	41	.	.	.
cord-004222-z4butywi	39	1	DH	DH	NNP
cord-004222-z4butywi	39	2	gene	gene	NN
cord-004222-z4butywi	39	3	and	and	CC
cord-004222-z4butywi	39	4	JH	JH	NNP
cord-004222-z4butywi	39	5	gene	gene	NN
cord-004222-z4butywi	39	6	usage	usage	NN
cord-004222-z4butywi	39	7	remained	remain	VBD
cord-004222-z4butywi	39	8	highly	highly	RB
cord-004222-z4butywi	39	9	correlated	correlate	VBN
cord-004222-z4butywi	39	10	with	with	IN
cord-004222-z4butywi	39	11	minor	minor	JJ
cord-004222-z4butywi	39	12	differences	difference	NNS
cord-004222-z4butywi	39	13	in	in	IN
cord-004222-z4butywi	39	14	specific	specific	JJ
cord-004222-z4butywi	39	15	genes	gene	NNS
cord-004222-z4butywi	39	16	(	(	-LRB-
cord-004222-z4butywi	39	17	Figs	fig	NNS
cord-004222-z4butywi	39	18	.	.	.
cord-004222-z4butywi	40	1	1b	1b	NNP
cord-004222-z4butywi	40	2	,	,	,
cord-004222-z4butywi	40	3	c	c	NNP
cord-004222-z4butywi	40	4	,	,	,
cord-004222-z4butywi	40	5	S1	S1	NNP
cord-004222-z4butywi	40	6	and	and	CC
cord-004222-z4butywi	40	7	S3b	S3b	NNP
cord-004222-z4butywi	40	8	,	,	,
cord-004222-z4butywi	40	9	c	c	NNP
cord-004222-z4butywi	40	10	)	)	-RRB-
cord-004222-z4butywi	40	11	.	.	.
cord-004222-z4butywi	41	1	Inter	inter	JJ
cord-004222-z4butywi	41	2	-	-	JJ
cord-004222-z4butywi	41	3	animal	animal	JJ
cord-004222-z4butywi	41	4	spleen	spleen	NN
cord-004222-z4butywi	41	5	gene	gene	NN
cord-004222-z4butywi	41	6	usage	usage	NN
cord-004222-z4butywi	41	7	was	be	VBD
cord-004222-z4butywi	41	8	highly	highly	RB
cord-004222-z4butywi	41	9	correlated	correlate	VBN
cord-004222-z4butywi	41	10	for	for	IN
cord-004222-z4butywi	41	11	all	all	DT
cord-004222-z4butywi	41	12	three	three	CD
cord-004222-z4butywi	41	13	heavy	heavy	JJ
cord-004222-z4butywi	41	14	chain	chain	NN
cord-004222-z4butywi	41	15	gene	gene	NN
cord-004222-z4butywi	41	16	segments	segment	NNS
cord-004222-z4butywi	41	17	(	(	-LRB-
cord-004222-z4butywi	41	18	Fig	Fig	NNP
cord-004222-z4butywi	41	19	.	.	.
cord-004222-z4butywi	41	20	S2	S2	NNP
cord-004222-z4butywi	41	21	)	)	-RRB-
cord-004222-z4butywi	41	22	.	.	.
cord-004222-z4butywi	42	1	Inter	inter	JJ
cord-004222-z4butywi	42	2	-	-	JJ
cord-004222-z4butywi	42	3	human	human	JJ
cord-004222-z4butywi	42	4	comparisons	comparison	NNS
cord-004222-z4butywi	42	5	yielded	yield	VBD
cord-004222-z4butywi	42	6	similar	similar	JJ
cord-004222-z4butywi	42	7	,	,	,
cord-004222-z4butywi	42	8	albeit	albeit	IN
cord-004222-z4butywi	42	9	slightly	slightly	RB
cord-004222-z4butywi	42	10	less	less	RBR
cord-004222-z4butywi	42	11	correlated	correlate	VBN
cord-004222-z4butywi	42	12	results	result	NNS
cord-004222-z4butywi	42	13	(	(	-LRB-
cord-004222-z4butywi	42	14	Fig	Fig	NNP
cord-004222-z4butywi	42	15	.	.	.
cord-004222-z4butywi	42	16	S2	S2	NNP
cord-004222-z4butywi	42	17	)	)	-RRB-
cord-004222-z4butywi	42	18	.	.	.
cord-004222-z4butywi	43	1	Intra	intra	JJ
cord-004222-z4butywi	43	2	-	-	JJ
cord-004222-z4butywi	43	3	species	species	JJ
cord-004222-z4butywi	43	4	VH	VH	NNP
cord-004222-z4butywi	43	5	and	and	CC
cord-004222-z4butywi	43	6	DH	DH	NNP
cord-004222-z4butywi	43	7	usage	usage	NN
cord-004222-z4butywi	43	8	comparisons	comparison	NNS
cord-004222-z4butywi	43	9	made	make	VBD
cord-004222-z4butywi	43	10	show	show	VB
cord-004222-z4butywi	43	11	much	much	RB
cord-004222-z4butywi	43	12	weaker	weak	JJR
cord-004222-z4butywi	43	13	correlations	correlation	NNS
cord-004222-z4butywi	43	14	with	with	IN
cord-004222-z4butywi	43	15	lower	low	JJR
cord-004222-z4butywi	43	16	R	r	NN
cord-004222-z4butywi	43	17	-	-	HYPH
cord-004222-z4butywi	43	18	squared	squared	JJ
cord-004222-z4butywi	43	19	values	value	NNS
cord-004222-z4butywi	43	20	than	than	IN
cord-004222-z4butywi	43	21	any	any	DT
cord-004222-z4butywi	43	22	other	other	JJ
cord-004222-z4butywi	43	23	previous	previous	JJ
cord-004222-z4butywi	43	24	comparison	comparison	NN
cord-004222-z4butywi	43	25	,	,	,
cord-004222-z4butywi	43	26	while	while	IN
cord-004222-z4butywi	43	27	surprisingly	surprisingly	RB
cord-004222-z4butywi	43	28	JH	JH	NNP
cord-004222-z4butywi	43	29	gene	gene	NN
cord-004222-z4butywi	43	30	usage	usage	NN
cord-004222-z4butywi	43	31	was	be	VBD
cord-004222-z4butywi	43	32	highly	highly	RB
cord-004222-z4butywi	43	33	correlated	correlate	VBN
cord-004222-z4butywi	43	34	(	(	-LRB-
cord-004222-z4butywi	43	35	Fig	fig	NN
cord-004222-z4butywi	43	36	.	.	.
cord-004222-z4butywi	43	37	S2	S2	NNP
cord-004222-z4butywi	43	38	)	)	-RRB-
cord-004222-z4butywi	43	39	.	.	.
cord-004222-z4butywi	44	1	Species	species	NN
cord-004222-z4butywi	44	2	specific	specific	JJ
cord-004222-z4butywi	44	3	gene	gene	NN
cord-004222-z4butywi	44	4	usage	usage	NN
cord-004222-z4butywi	44	5	biases	bias	NNS
cord-004222-z4butywi	44	6	were	be	VBD
cord-004222-z4butywi	44	7	more	more	RBR
cord-004222-z4butywi	44	8	predominant	predominant	JJ
cord-004222-z4butywi	44	9	in	in	IN
cord-004222-z4butywi	44	10	variable	variable	JJ
cord-004222-z4butywi	44	11	genes	gene	NNS
cord-004222-z4butywi	44	12	(	(	-LRB-
cord-004222-z4butywi	44	13	VH	VH	NNP
cord-004222-z4butywi	44	14	and	and	CC
cord-004222-z4butywi	44	15	VK	VK	NNP
cord-004222-z4butywi	44	16	)	)	-RRB-
cord-004222-z4butywi	44	17	than	than	IN
cord-004222-z4butywi	44	18	in	in	IN
cord-004222-z4butywi	44	19	joining	join	VBG
cord-004222-z4butywi	44	20	genes	gene	NNS
cord-004222-z4butywi	44	21	(	(	-LRB-
cord-004222-z4butywi	44	22	JH	JH	NNP
cord-004222-z4butywi	44	23	and	and	CC
cord-004222-z4butywi	44	24	JK	JK	NNP
cord-004222-z4butywi	44	25	)	)	-RRB-
cord-004222-z4butywi	45	1	(	(	-LRB-
cord-004222-z4butywi	45	2	Fig	Fig	NNP
cord-004222-z4butywi	45	3	.	.	.
cord-004222-z4butywi	45	4	S3a	s3a	NN
cord-004222-z4butywi	45	5	-	-	HYPH
cord-004222-z4butywi	45	6	e	e	NN
cord-004222-z4butywi	45	7	)	)	-RRB-
cord-004222-z4butywi	45	8	.	.	.
cord-004222-z4butywi	46	1	We	-PRON-	PRP
cord-004222-z4butywi	46	2	hypothesize	hypothesize	VBP
cord-004222-z4butywi	46	3	that	that	IN
cord-004222-z4butywi	46	4	this	this	DT
cord-004222-z4butywi	46	5	may	may	MD
cord-004222-z4butywi	46	6	be	be	VB
cord-004222-z4butywi	46	7	due	due	JJ
cord-004222-z4butywi	46	8	to	to	IN
cord-004222-z4butywi	46	9	species	species	NN
cord-004222-z4butywi	46	10	specific	specific	JJ
cord-004222-z4butywi	46	11	differences	difference	NNS
cord-004222-z4butywi	46	12	in	in	IN
cord-004222-z4butywi	46	13	variable	variable	JJ
cord-004222-z4butywi	46	14	gene	gene	NN
cord-004222-z4butywi	46	15	order	order	NN
cord-004222-z4butywi	46	16	,	,	,
cord-004222-z4butywi	46	17	but	but	CC
cord-004222-z4butywi	46	18	not	not	RB
cord-004222-z4butywi	46	19	joining	join	VBG
cord-004222-z4butywi	46	20	gene	gene	NN
cord-004222-z4butywi	46	21	order	order	NN
cord-004222-z4butywi	46	22	at	at	IN
cord-004222-z4butywi	46	23	the	the	DT
cord-004222-z4butywi	46	24	genomic	genomic	JJ
cord-004222-z4butywi	46	25	loci	locus	NNS
cord-004222-z4butywi	46	26	11	11	CD
cord-004222-z4butywi	46	27	,	,	,
cord-004222-z4butywi	46	28	although	although	IN
cord-004222-z4butywi	46	29	no	no	DT
cord-004222-z4butywi	46	30	significant	significant	JJ
cord-004222-z4butywi	46	31	correlation	correlation	NN
cord-004222-z4butywi	46	32	between	between	IN
cord-004222-z4butywi	46	33	variable	variable	JJ
cord-004222-z4butywi	46	34	gene	gene	NN
cord-004222-z4butywi	46	35	order	order	NN
cord-004222-z4butywi	46	36	and	and	CC
cord-004222-z4butywi	46	37	gene	gene	NN
cord-004222-z4butywi	46	38	usage	usage	NN
cord-004222-z4butywi	46	39	in	in	IN
cord-004222-z4butywi	46	40	the	the	DT
cord-004222-z4butywi	46	41	OmniRat	OmniRat	NNP
cord-004222-z4butywi	46	42	was	be	VBD
cord-004222-z4butywi	46	43	found	find	VBN
cord-004222-z4butywi	46	44	(	(	-LRB-
cord-004222-z4butywi	46	45	data	datum	NNS
cord-004222-z4butywi	46	46	not	not	RB
cord-004222-z4butywi	46	47	shown	show	VBN
cord-004222-z4butywi	46	48	)	)	-RRB-
cord-004222-z4butywi	46	49	.	.	.
cord-004222-z4butywi	47	1	OmniRats	OmniRats	NNP
cord-004222-z4butywi	47	2	show	show	VBP
cord-004222-z4butywi	47	3	a	a	DT
cord-004222-z4butywi	47	4	preference	preference	NN
cord-004222-z4butywi	47	5	for	for	IN
cord-004222-z4butywi	47	6	DH	DH	NNP
cord-004222-z4butywi	47	7	gene	gene	NN
cord-004222-z4butywi	47	8	families	family	NNS
cord-004222-z4butywi	47	9	of	of	IN
cord-004222-z4butywi	47	10	shorter	short	JJR
cord-004222-z4butywi	47	11	average	average	JJ
cord-004222-z4butywi	47	12	length	length	NN
cord-004222-z4butywi	47	13	such	such	JJ
cord-004222-z4butywi	47	14	as	as	IN
cord-004222-z4butywi	47	15	DH1	DH1	NNP
cord-004222-z4butywi	47	16	,	,	,
cord-004222-z4butywi	47	17	DH5	dh5	NN
cord-004222-z4butywi	47	18	,	,	,
cord-004222-z4butywi	47	19	DH6	dh6	NN
cord-004222-z4butywi	47	20	and	and	CC
cord-004222-z4butywi	47	21	DH7	dh7	NN
cord-004222-z4butywi	47	22	as	as	IN
cord-004222-z4butywi	47	23	compared	compare	VBN
cord-004222-z4butywi	47	24	to	to	IN
cord-004222-z4butywi	47	25	humans	human	NNS
cord-004222-z4butywi	47	26	which	which	WDT
cord-004222-z4butywi	47	27	show	show	VBP
cord-004222-z4butywi	47	28	a	a	DT
cord-004222-z4butywi	47	29	higher	high	JJR
cord-004222-z4butywi	47	30	representation	representation	NN
cord-004222-z4butywi	47	31	of	of	IN
cord-004222-z4butywi	47	32	longer	long	JJR
cord-004222-z4butywi	47	33	DH	DH	NNP
cord-004222-z4butywi	47	34	genes	gene	NNS
cord-004222-z4butywi	47	35	from	from	IN
cord-004222-z4butywi	47	36	DH2	DH2	NNP
cord-004222-z4butywi	47	37	,	,	,
cord-004222-z4butywi	47	38	DH3	dh3	NN
cord-004222-z4butywi	47	39	,	,	,
cord-004222-z4butywi	47	40	and	and	CC
cord-004222-z4butywi	47	41	DH4	DH4	NNP
cord-004222-z4butywi	47	42	families	family	NNS
cord-004222-z4butywi	47	43	with	with	IN
cord-004222-z4butywi	47	44	the	the	DT
cord-004222-z4butywi	47	45	exception	exception	NN
cord-004222-z4butywi	47	46	of	of	IN
cord-004222-z4butywi	47	47	DH3	dh3	NN
cord-004222-z4butywi	47	48	-	-	HYPH
cord-004222-z4butywi	47	49	9	9	CD
cord-004222-z4butywi	47	50	which	which	WDT
cord-004222-z4butywi	47	51	appears	appear	VBZ
cord-004222-z4butywi	47	52	at	at	IN
cord-004222-z4butywi	47	53	similar	similar	JJ
cord-004222-z4butywi	47	54	frequencies	frequency	NNS
cord-004222-z4butywi	47	55	between	between	IN
cord-004222-z4butywi	47	56	each	each	DT
cord-004222-z4butywi	47	57	species	specie	NNS
cord-004222-z4butywi	47	58	(	(	-LRB-
cord-004222-z4butywi	47	59	Figs	fig	NNS
cord-004222-z4butywi	47	60	.	.	.
cord-004222-z4butywi	48	1	1b	1b	CD
cord-004222-z4butywi	48	2	and	and	CC
cord-004222-z4butywi	48	3	S3b	S3b	NNP
cord-004222-z4butywi	48	4	)	)	-RRB-
cord-004222-z4butywi	48	5	.	.	.
cord-004222-z4butywi	49	1	VK	VK	NNP
cord-004222-z4butywi	49	2	and	and	CC
cord-004222-z4butywi	49	3	JK	JK	NNP
cord-004222-z4butywi	49	4	gene	gene	NN
cord-004222-z4butywi	49	5	usage	usage	NN
cord-004222-z4butywi	49	6	frequencies	frequency	NNS
cord-004222-z4butywi	49	7	were	be	VBD
cord-004222-z4butywi	49	8	very	very	RB
cord-004222-z4butywi	49	9	similar	similar	JJ
cord-004222-z4butywi	49	10	for	for	IN
cord-004222-z4butywi	49	11	all	all	DT
cord-004222-z4butywi	49	12	comparisons	comparison	NNS
cord-004222-z4butywi	49	13	made	make	VBN
cord-004222-z4butywi	49	14	(	(	-LRB-
cord-004222-z4butywi	49	15	Figs	fig	NNS
cord-004222-z4butywi	49	16	.	.	.
cord-004222-z4butywi	50	1	S1	S1	NNP
cord-004222-z4butywi	50	2	-	-	HYPH
cord-004222-z4butywi	50	3	3	3	NNP
cord-004222-z4butywi	50	4	and	and	CC
cord-004222-z4butywi	50	5	S6	S6	NNP
cord-004222-z4butywi	50	6	)	)	-RRB-
cord-004222-z4butywi	50	7	.	.	.
cord-004222-z4butywi	51	1	Differences	difference	NNS
cord-004222-z4butywi	51	2	in	in	IN
cord-004222-z4butywi	51	3	CDR3	CDR3	NNP
cord-004222-z4butywi	51	4	length	length	NN
cord-004222-z4butywi	51	5	distributions	distribution	NNS
cord-004222-z4butywi	51	6	of	of	IN
cord-004222-z4butywi	51	7	each	each	DT
cord-004222-z4butywi	51	8	repertoire	repertoire	NN
cord-004222-z4butywi	51	9	were	be	VBD
cord-004222-z4butywi	51	10	next	next	RB
cord-004222-z4butywi	51	11	determined	determined	JJ
cord-004222-z4butywi	51	12	.	.	.
cord-004222-z4butywi	52	1	The	the	DT
cord-004222-z4butywi	52	2	mean	mean	JJ
cord-004222-z4butywi	52	3	heavy	heavy	JJ
cord-004222-z4butywi	52	4	chain	chain	NN
cord-004222-z4butywi	52	5	CDR3	CDR3	NNP
cord-004222-z4butywi	52	6	(	(	-LRB-
cord-004222-z4butywi	52	7	CDRH3	cdrh3	NN
cord-004222-z4butywi	52	8	)	)	-RRB-
cord-004222-z4butywi	52	9	length	length	NN
cord-004222-z4butywi	52	10	in	in	IN
cord-004222-z4butywi	52	11	humans	human	NNS
cord-004222-z4butywi	52	12	is	be	VBZ
cord-004222-z4butywi	52	13	14.8	14.8	CD
cord-004222-z4butywi	52	14	amino	amino	JJ
cord-004222-z4butywi	52	15	acids	acid	NNS
cord-004222-z4butywi	52	16	,	,	,
cord-004222-z4butywi	52	17	while	while	IN
cord-004222-z4butywi	52	18	in	in	IN
cord-004222-z4butywi	52	19	the	the	DT
cord-004222-z4butywi	52	20	OmniRat	OmniRat	NNP
cord-004222-z4butywi	52	21	we	-PRON-	PRP
cord-004222-z4butywi	52	22	observed	observe	VBD
cord-004222-z4butywi	52	23	a	a	DT
cord-004222-z4butywi	52	24	mean	mean	JJ
cord-004222-z4butywi	52	25	CDRH3	cdrh3	NN
cord-004222-z4butywi	52	26	length	length	NN
cord-004222-z4butywi	52	27	that	that	WDT
cord-004222-z4butywi	52	28	is	be	VBZ
cord-004222-z4butywi	52	29	shorter	short	JJR
cord-004222-z4butywi	52	30	with	with	IN
cord-004222-z4butywi	52	31	a	a	DT
cord-004222-z4butywi	52	32	mean	mean	JJ
cord-004222-z4butywi	52	33	length	length	NN
cord-004222-z4butywi	52	34	of	of	IN
cord-004222-z4butywi	52	35	12.1	12.1	CD
cord-004222-z4butywi	52	36	amino	amino	NN
cord-004222-z4butywi	52	37	acids	acid	NNS
cord-004222-z4butywi	52	38	(	(	-LRB-
cord-004222-z4butywi	52	39	Fig	Fig	NNP
cord-004222-z4butywi	52	40	.	.	.
cord-004222-z4butywi	52	41	2a	2a	CD
cord-004222-z4butywi	52	42	)	)	-RRB-
cord-004222-z4butywi	52	43	.	.	.
cord-004222-z4butywi	53	1	There	there	EX
cord-004222-z4butywi	53	2	are	be	VBP
cord-004222-z4butywi	53	3	minor	minor	JJ
cord-004222-z4butywi	53	4	differences	difference	NNS
cord-004222-z4butywi	53	5	in	in	IN
cord-004222-z4butywi	53	6	the	the	DT
cord-004222-z4butywi	53	7	kappa	kappa	NN
cord-004222-z4butywi	53	8	light	light	NN
cord-004222-z4butywi	53	9	chain	chain	NN
cord-004222-z4butywi	53	10	(	(	-LRB-
cord-004222-z4butywi	53	11	CDRL3	CDRL3	NNP
cord-004222-z4butywi	53	12	)	)	-RRB-
cord-004222-z4butywi	53	13	lengths	length	NNS
cord-004222-z4butywi	53	14	between	between	IN
cord-004222-z4butywi	53	15	species	specie	NNS
cord-004222-z4butywi	53	16	with	with	IN
cord-004222-z4butywi	53	17	near	near	JJ
cord-004222-z4butywi	53	18	identical	identical	JJ
cord-004222-z4butywi	53	19	average	average	JJ
cord-004222-z4butywi	53	20	lengths	length	NNS
cord-004222-z4butywi	53	21	of	of	IN
cord-004222-z4butywi	53	22	9.0	9.0	CD
cord-004222-z4butywi	53	23	and	and	CC
cord-004222-z4butywi	53	24	9.1	9.1	CD
cord-004222-z4butywi	53	25	for	for	IN
cord-004222-z4butywi	53	26	OmniRats	OmniRats	NNP
cord-004222-z4butywi	53	27	and	and	CC
cord-004222-z4butywi	53	28	humans	human	NNS
cord-004222-z4butywi	53	29	respectively	respectively	RB
cord-004222-z4butywi	53	30	(	(	-LRB-
cord-004222-z4butywi	53	31	Fig	fig	NN
cord-004222-z4butywi	53	32	.	.	.
cord-004222-z4butywi	53	33	S6c	S6c	NNP
cord-004222-z4butywi	53	34	)	)	-RRB-
cord-004222-z4butywi	53	35	.	.	.
cord-004222-z4butywi	54	1	The	the	DT
cord-004222-z4butywi	54	2	frequency	frequency	NN
cord-004222-z4butywi	54	3	of	of	IN
cord-004222-z4butywi	54	4	light	light	JJ
cord-004222-z4butywi	54	5	chains	chain	NNS
cord-004222-z4butywi	54	6	with	with	IN
cord-004222-z4butywi	54	7	a	a	DT
cord-004222-z4butywi	54	8	CDR3	CDR3	NNP
cord-004222-z4butywi	54	9	of	of	IN
cord-004222-z4butywi	54	10	5	5	CD
cord-004222-z4butywi	54	11	amino	amino	NN
cord-004222-z4butywi	54	12	acids	acid	NNS
cord-004222-z4butywi	54	13	in	in	IN
cord-004222-z4butywi	54	14	length	length	NN
cord-004222-z4butywi	54	15	is	be	VBZ
cord-004222-z4butywi	54	16	an	an	DT
cord-004222-z4butywi	54	17	important	important	JJ
cord-004222-z4butywi	54	18	consideration	consideration	NN
cord-004222-z4butywi	54	19	when	when	WRB
cord-004222-z4butywi	54	20	choosing	choose	VBG
cord-004222-z4butywi	54	21	a	a	DT
cord-004222-z4butywi	54	22	model	model	NN
cord-004222-z4butywi	54	23	animal	animal	NN
cord-004222-z4butywi	54	24	for	for	IN
cord-004222-z4butywi	54	25	vaccination	vaccination	NN
cord-004222-z4butywi	54	26	experiments	experiment	NNS
cord-004222-z4butywi	54	27	involving	involve	VBG
cord-004222-z4butywi	54	28	the	the	DT
cord-004222-z4butywi	54	29	germline	germline	NN
cord-004222-z4butywi	54	30	targeting	target	VBG
cord-004222-z4butywi	54	31	immunogen	immunogen	NN
cord-004222-z4butywi	54	32	eOD	eod	NN
cord-004222-z4butywi	54	33	-	-	:
cord-004222-z4butywi	54	34	GT8	gt8	NN
cord-004222-z4butywi	54	35	which	which	WDT
cord-004222-z4butywi	54	36	is	be	VBZ
cord-004222-z4butywi	54	37	in	in	IN
cord-004222-z4butywi	54	38	human	human	JJ
cord-004222-z4butywi	54	39	clinical	clinical	JJ
cord-004222-z4butywi	54	40	trials	trial	NNS
cord-004222-z4butywi	54	41	3	3	CD
cord-004222-z4butywi	54	42	,	,	,
cord-004222-z4butywi	54	43	14	14	CD
cord-004222-z4butywi	54	44	,	,	,
cord-004222-z4butywi	54	45	19	19	CD
cord-004222-z4butywi	54	46	.	.	.
cord-004222-z4butywi	55	1	This	this	DT
cord-004222-z4butywi	55	2	frequency	frequency	NN
cord-004222-z4butywi	55	3	of	of	IN
cord-004222-z4butywi	55	4	5-amino	5-amino	CD
cord-004222-z4butywi	55	5	acid	acid	NN
cord-004222-z4butywi	55	6	CDRL3s	CDRL3s	NNP
cord-004222-z4butywi	55	7	was	be	VBD
cord-004222-z4butywi	55	8	lower	low	JJR
cord-004222-z4butywi	55	9	in	in	IN
cord-004222-z4butywi	55	10	OmniRats	OmniRats	NNP
cord-004222-z4butywi	55	11	(	(	-LRB-
cord-004222-z4butywi	55	12	0.02	0.02	CD
cord-004222-z4butywi	55	13	%	%	NN
cord-004222-z4butywi	55	14	)	)	-RRB-
cord-004222-z4butywi	55	15	than	than	IN
cord-004222-z4butywi	55	16	in	in	IN
cord-004222-z4butywi	55	17	humans	human	NNS
cord-004222-z4butywi	55	18	(	(	-LRB-
cord-004222-z4butywi	55	19	0.56	0.56	CD
cord-004222-z4butywi	55	20	%	%	NN
cord-004222-z4butywi	55	21	)	)	-RRB-
cord-004222-z4butywi	56	1	i.e.	i.e.	FW
cord-004222-z4butywi	56	2	a	a	DT
cord-004222-z4butywi	56	3	factor	factor	NN
cord-004222-z4butywi	56	4	of	of	IN
cord-004222-z4butywi	56	5	28	28	CD
cord-004222-z4butywi	57	1	(	(	-LRB-
cord-004222-z4butywi	57	2	Fig	Fig	NNP
cord-004222-z4butywi	57	3	.	.	.
cord-004222-z4butywi	57	4	S6c	S6c	NNP
cord-004222-z4butywi	57	5	)	)	-RRB-
cord-004222-z4butywi	57	6	.	.	.
cord-004222-z4butywi	58	1	After	after	IN
cord-004222-z4butywi	58	2	observing	observe	VBG
cord-004222-z4butywi	58	3	a	a	DT
cord-004222-z4butywi	58	4	tendency	tendency	NN
cord-004222-z4butywi	58	5	for	for	IN
cord-004222-z4butywi	58	6	shorter	short	JJR
cord-004222-z4butywi	58	7	CDRH3	cdrh3	NN
cord-004222-z4butywi	58	8	lengths	length	NNS
cord-004222-z4butywi	58	9	in	in	IN
cord-004222-z4butywi	58	10	the	the	DT
cord-004222-z4butywi	58	11	OmniRat	omnirat	NN
cord-004222-z4butywi	58	12	as	as	IN
cord-004222-z4butywi	58	13	compared	compare	VBN
cord-004222-z4butywi	58	14	to	to	IN
cord-004222-z4butywi	58	15	humans	human	NNS
cord-004222-z4butywi	58	16	,	,	,
cord-004222-z4butywi	58	17	we	-PRON-	PRP
cord-004222-z4butywi	58	18	wanted	want	VBD
cord-004222-z4butywi	58	19	to	to	TO
cord-004222-z4butywi	58	20	know	know	VB
cord-004222-z4butywi	58	21	if	if	IN
cord-004222-z4butywi	58	22	the	the	DT
cord-004222-z4butywi	58	23	number	number	NN
cord-004222-z4butywi	58	24	of	of	IN
cord-004222-z4butywi	58	25	N	N	NNP
cord-004222-z4butywi	58	26	and	and	CC
cord-004222-z4butywi	58	27	P	p	NN
cord-004222-z4butywi	58	28	nucleotide	nucleotide	JJ
cord-004222-z4butywi	58	29	additions	addition	NNS
cord-004222-z4butywi	58	30	in	in	IN
cord-004222-z4butywi	58	31	the	the	DT
cord-004222-z4butywi	58	32	heavy	heavy	JJ
cord-004222-z4butywi	58	33	chain	chain	NN
cord-004222-z4butywi	58	34	V	v	NN
cord-004222-z4butywi	58	35	-	-	HYPH
cord-004222-z4butywi	58	36	D	D	NNP
cord-004222-z4butywi	58	37	and	and	CC
cord-004222-z4butywi	58	38	D	D	NNP
cord-004222-z4butywi	58	39	-	-	HYPH
cord-004222-z4butywi	58	40	J	J	NNP
cord-004222-z4butywi	58	41	junction	junction	NN
cord-004222-z4butywi	58	42	sites	site	NNS
cord-004222-z4butywi	58	43	were	be	VBD
cord-004222-z4butywi	58	44	different	different	JJ
cord-004222-z4butywi	58	45	.	.	.
cord-004222-z4butywi	59	1	Figure	figure	NN
cord-004222-z4butywi	59	2	2b	2b	CD
cord-004222-z4butywi	59	3	,	,	,
cord-004222-z4butywi	59	4	c	c	NN
cord-004222-z4butywi	59	5	shows	show	VBZ
cord-004222-z4butywi	59	6	average	average	JJ
cord-004222-z4butywi	59	7	V	V	NNP
cord-004222-z4butywi	59	8	-	-	HYPH
cord-004222-z4butywi	59	9	D	d	NN
cord-004222-z4butywi	59	10	and	and	CC
cord-004222-z4butywi	59	11	D	D	NNP
cord-004222-z4butywi	59	12	-	-	HYPH
cord-004222-z4butywi	59	13	J	J	NNP
cord-004222-z4butywi	59	14	junction	junction	NN
cord-004222-z4butywi	59	15	nucleotide	nucleotide	JJ
cord-004222-z4butywi	59	16	addition	addition	NN
cord-004222-z4butywi	59	17	lengths	length	NNS
cord-004222-z4butywi	59	18	in	in	IN
cord-004222-z4butywi	59	19	the	the	DT
cord-004222-z4butywi	59	20	OmniRat	OmniRat	NNP
cord-004222-z4butywi	59	21	are	be	VBP
cord-004222-z4butywi	59	22	indeed	indeed	RB
cord-004222-z4butywi	59	23	shorter	short	JJR
cord-004222-z4butywi	59	24	as	as	IN
cord-004222-z4butywi	59	25	compared	compare	VBN
cord-004222-z4butywi	59	26	to	to	IN
cord-004222-z4butywi	59	27	humans	human	NNS
cord-004222-z4butywi	59	28	.	.	.
cord-004222-z4butywi	60	1	Nucleotide	nucleotide	JJ
cord-004222-z4butywi	60	2	additions	addition	NNS
cord-004222-z4butywi	60	3	in	in	IN
cord-004222-z4butywi	60	4	the	the	DT
cord-004222-z4butywi	60	5	V	V	NNP
cord-004222-z4butywi	60	6	-	-	HYPH
cord-004222-z4butywi	60	7	J	J	NNP
cord-004222-z4butywi	60	8	junctions	junction	NNS
cord-004222-z4butywi	60	9	of	of	IN
cord-004222-z4butywi	60	10	kappa	kappa	NN
cord-004222-z4butywi	60	11	chains	chain	NNS
cord-004222-z4butywi	60	12	are	be	VBP
cord-004222-z4butywi	60	13	also	also	RB
cord-004222-z4butywi	60	14	shorter	short	JJR
cord-004222-z4butywi	60	15	on	on	IN
cord-004222-z4butywi	60	16	average	average	JJ
cord-004222-z4butywi	60	17	as	as	IN
cord-004222-z4butywi	60	18	compared	compare	VBN
cord-004222-z4butywi	60	19	to	to	IN
cord-004222-z4butywi	60	20	humans	human	NNS
cord-004222-z4butywi	60	21	(	(	-LRB-
cord-004222-z4butywi	60	22	Fig	Fig	NNP
cord-004222-z4butywi	60	23	.	.	.
cord-004222-z4butywi	60	24	S6e	s6e	NN
cord-004222-z4butywi	60	25	)	)	-RRB-
cord-004222-z4butywi	60	26	.	.	.
cord-004222-z4butywi	61	1	The	the	DT
cord-004222-z4butywi	61	2	longest	long	JJS
cord-004222-z4butywi	61	3	DH	dh	NN
cord-004222-z4butywi	61	4	gene	gene	NN
cord-004222-z4butywi	61	5	segments	segment	NNS
cord-004222-z4butywi	61	6	are	be	VBP
cord-004222-z4butywi	61	7	found	find	VBN
cord-004222-z4butywi	61	8	in	in	IN
cord-004222-z4butywi	61	9	the	the	DT
cord-004222-z4butywi	61	10	DH3	dh3	NN
cord-004222-z4butywi	61	11	family	family	NN
cord-004222-z4butywi	61	12	and	and	CC
cord-004222-z4butywi	61	13	the	the	DT
cord-004222-z4butywi	61	14	longest	long	JJS
cord-004222-z4butywi	61	15	JH	JH	NNP
cord-004222-z4butywi	61	16	gene	gene	NN
cord-004222-z4butywi	61	17	segments	segment	NNS
cord-004222-z4butywi	61	18	come	come	VBP
cord-004222-z4butywi	61	19	from	from	IN
cord-004222-z4butywi	61	20	the	the	DT
cord-004222-z4butywi	61	21	JH6	JH6	NNP
cord-004222-z4butywi	61	22	gene	gene	NN
cord-004222-z4butywi	61	23	family	family	NN
cord-004222-z4butywi	61	24	.	.	.
cord-004222-z4butywi	62	1	Gene	gene	NN
cord-004222-z4butywi	62	2	segments	segment	NNS
cord-004222-z4butywi	62	3	from	from	IN
cord-004222-z4butywi	62	4	these	these	DT
cord-004222-z4butywi	62	5	families	family	NNS
cord-004222-z4butywi	62	6	are	be	VBP
cord-004222-z4butywi	62	7	important	important	JJ
cord-004222-z4butywi	62	8	contributors	contributor	NNS
cord-004222-z4butywi	62	9	to	to	IN
cord-004222-z4butywi	62	10	the	the	DT
cord-004222-z4butywi	62	11	generation	generation	NN
cord-004222-z4butywi	62	12	of	of	IN
cord-004222-z4butywi	62	13	unusually	unusually	RB
cord-004222-z4butywi	62	14	long	long	JJ
cord-004222-z4butywi	62	15	CDRH3s	cdrh3s	NN
cord-004222-z4butywi	62	16	in	in	IN
cord-004222-z4butywi	62	17	humans	human	NNS
cord-004222-z4butywi	62	18	and	and	CC
cord-004222-z4butywi	62	19	are	be	VBP
cord-004222-z4butywi	62	20	consistently	consistently	RB
cord-004222-z4butywi	62	21	found	find	VBN
cord-004222-z4butywi	62	22	in	in	IN
cord-004222-z4butywi	62	23	certain	certain	JJ
cord-004222-z4butywi	62	24	broadly	broadly	RB
cord-004222-z4butywi	62	25	neutralizing	neutralize	VBG
cord-004222-z4butywi	62	26	antibodies	antibody	NNS
cord-004222-z4butywi	62	27	(	(	-LRB-
cord-004222-z4butywi	62	28	bnAbs	bnabs	NN
cord-004222-z4butywi	62	29	)	)	-RRB-
cord-004222-z4butywi	62	30	that	that	WDT
cord-004222-z4butywi	62	31	bind	bind	VBP
cord-004222-z4butywi	62	32	to	to	IN
cord-004222-z4butywi	62	33	the	the	DT
cord-004222-z4butywi	62	34	human	human	JJ
cord-004222-z4butywi	62	35	immunodeficiency	immunodeficiency	NN
cord-004222-z4butywi	62	36	virus	virus	NN
cord-004222-z4butywi	62	37	(	(	-LRB-
cord-004222-z4butywi	62	38	HIV	HIV	NNP
cord-004222-z4butywi	62	39	)	)	-RRB-
cord-004222-z4butywi	62	40	envelope	envelope	NN
cord-004222-z4butywi	62	41	(	(	-LRB-
cord-004222-z4butywi	62	42	Env	Env	NNP
cord-004222-z4butywi	62	43	)	)	-RRB-
cord-004222-z4butywi	62	44	glycoprotein	glycoprotein	NN
cord-004222-z4butywi	62	45	,	,	,
cord-004222-z4butywi	62	46	indicating	indicate	VBG
cord-004222-z4butywi	62	47	the	the	DT
cord-004222-z4butywi	62	48	importance	importance	NN
cord-004222-z4butywi	62	49	of	of	IN
cord-004222-z4butywi	62	50	these	these	DT
cord-004222-z4butywi	62	51	rearrangements	rearrangement	NNS
cord-004222-z4butywi	62	52	in	in	IN
cord-004222-z4butywi	62	53	HIV	HIV	NNP
cord-004222-z4butywi	62	54	vaccine	vaccine	NN
cord-004222-z4butywi	62	55	studies	study	NNS
cord-004222-z4butywi	62	56	20	20	CD
cord-004222-z4butywi	62	57	.	.	.
cord-004222-z4butywi	63	1	On	on	IN
cord-004222-z4butywi	63	2	average	average	JJ
cord-004222-z4butywi	63	3	,	,	,
cord-004222-z4butywi	63	4	the	the	DT
cord-004222-z4butywi	63	5	frequency	frequency	NN
cord-004222-z4butywi	63	6	of	of	IN
cord-004222-z4butywi	63	7	antibodies	antibody	NNS
cord-004222-z4butywi	63	8	with	with	IN
cord-004222-z4butywi	63	9	D3-J6	D3-J6	NNP
cord-004222-z4butywi	63	10	rearrangements	rearrangement	NNS
cord-004222-z4butywi	63	11	in	in	IN
cord-004222-z4butywi	63	12	OmniRats	OmniRats	NNP
cord-004222-z4butywi	63	13	is	be	VBZ
cord-004222-z4butywi	63	14	0.012	0.012	CD
cord-004222-z4butywi	63	15	with	with	IN
cord-004222-z4butywi	63	16	little	little	JJ
cord-004222-z4butywi	63	17	variation	variation	NN
cord-004222-z4butywi	63	18	,	,	,
cord-004222-z4butywi	63	19	while	while	IN
cord-004222-z4butywi	63	20	in	in	IN
cord-004222-z4butywi	63	21	humans	human	NNS
cord-004222-z4butywi	63	22	the	the	DT
cord-004222-z4butywi	63	23	frequency	frequency	NN
cord-004222-z4butywi	63	24	of	of	IN
cord-004222-z4butywi	63	25	these	these	DT
cord-004222-z4butywi	63	26	antibody	antibody	NN
cord-004222-z4butywi	63	27	species	species	NN
cord-004222-z4butywi	63	28	is	be	VBZ
cord-004222-z4butywi	63	29	more	more	RBR
cord-004222-z4butywi	63	30	variable	variable	JJ
cord-004222-z4butywi	63	31	between	between	IN
cord-004222-z4butywi	63	32	subjects	subject	NNS
cord-004222-z4butywi	63	33	with	with	IN
cord-004222-z4butywi	63	34	a	a	DT
cord-004222-z4butywi	63	35	higher	high	JJR
cord-004222-z4butywi	63	36	mean	mean	NN
cord-004222-z4butywi	63	37	of	of	IN
cord-004222-z4butywi	63	38	0.028	0.028	CD
cord-004222-z4butywi	64	1	(	(	-LRB-
cord-004222-z4butywi	64	2	Fig	Fig	NNP
cord-004222-z4butywi	64	3	.	.	.
cord-004222-z4butywi	64	4	2d	2d	NNP
cord-004222-z4butywi	64	5	)	)	-RRB-
cord-004222-z4butywi	64	6	.	.	.
cord-004222-z4butywi	65	1	The	the	DT
cord-004222-z4butywi	65	2	preference	preference	NN
cord-004222-z4butywi	65	3	of	of	IN
cord-004222-z4butywi	65	4	OmniRats	OmniRats	NNP
cord-004222-z4butywi	65	5	for	for	IN
cord-004222-z4butywi	65	6	shorter	short	JJR
cord-004222-z4butywi	65	7	CDRH3	cdrh3	NN
cord-004222-z4butywi	65	8	lengths	length	NNS
cord-004222-z4butywi	65	9	and	and	CC
cord-004222-z4butywi	65	10	DH	dh	NN
cord-004222-z4butywi	65	11	gene	gene	NN
cord-004222-z4butywi	65	12	segments	segment	NNS
cord-004222-z4butywi	65	13	can	can	MD
cord-004222-z4butywi	65	14	be	be	VB
cord-004222-z4butywi	65	15	placed	place	VBN
cord-004222-z4butywi	65	16	in	in	IN
cord-004222-z4butywi	65	17	the	the	DT
cord-004222-z4butywi	65	18	context	context	NN
cord-004222-z4butywi	65	19	of	of	IN
cord-004222-z4butywi	65	20	shorter	short	JJR
cord-004222-z4butywi	65	21	DH	dh	NN
cord-004222-z4butywi	65	22	gene	gene	NN
cord-004222-z4butywi	65	23	lengths	length	NNS
cord-004222-z4butywi	65	24	in	in	IN
cord-004222-z4butywi	65	25	the	the	DT
cord-004222-z4butywi	65	26	wild	wild	JJ
cord-004222-z4butywi	65	27	-	-	HYPH
cord-004222-z4butywi	65	28	type	type	NN
cord-004222-z4butywi	65	29	rat	rat	NN
cord-004222-z4butywi	65	30	(	(	-LRB-
cord-004222-z4butywi	65	31	Rattus	Rattus	NNP
cord-004222-z4butywi	65	32	norvegicus	norvegicus	NN
cord-004222-z4butywi	65	33	)	)	-RRB-
cord-004222-z4butywi	65	34	as	as	IN
cord-004222-z4butywi	65	35	compared	compare	VBN
cord-004222-z4butywi	65	36	to	to	IN
cord-004222-z4butywi	65	37	human	human	JJ
cord-004222-z4butywi	65	38	DH	dh	NN
cord-004222-z4butywi	65	39	genes	gene	NNS
cord-004222-z4butywi	65	40	(	(	-LRB-
cord-004222-z4butywi	65	41	Fig	Fig	NNP
cord-004222-z4butywi	65	42	.	.	.
cord-004222-z4butywi	65	43	2e	2e	NNP
cord-004222-z4butywi	65	44	)	)	-RRB-
cord-004222-z4butywi	65	45	,	,	,
cord-004222-z4butywi	65	46	indicating	indicate	VBG
cord-004222-z4butywi	65	47	a	a	DT
cord-004222-z4butywi	65	48	possible	possible	JJ
cord-004222-z4butywi	65	49	biologically	biologically	RB
cord-004222-z4butywi	65	50	intrinsic	intrinsic	JJ
cord-004222-z4butywi	65	51	bias	bias	NN
cord-004222-z4butywi	65	52	.	.	.
cord-004222-z4butywi	66	1	We	-PRON-	PRP
cord-004222-z4butywi	66	2	used	use	VBD
cord-004222-z4butywi	66	3	IGoR	IGoR	NNP
cord-004222-z4butywi	66	4	21	21	CD
cord-004222-z4butywi	66	5	to	to	TO
cord-004222-z4butywi	66	6	infer	infer	VB
cord-004222-z4butywi	66	7	recombination	recombination	NN
cord-004222-z4butywi	66	8	models	model	NNS
cord-004222-z4butywi	66	9	for	for	IN
cord-004222-z4butywi	66	10	each	each	DT
cord-004222-z4butywi	66	11	individual	individual	JJ
cord-004222-z4butywi	66	12	repertoire	repertoire	NN
cord-004222-z4butywi	66	13	from	from	IN
cord-004222-z4butywi	66	14	100,000	100,000	CD
cord-004222-z4butywi	66	15	unmutated	unmutated	JJ
cord-004222-z4butywi	66	16	sequences	sequence	NNS
cord-004222-z4butywi	66	17	allowing	allow	VBG
cord-004222-z4butywi	66	18	for	for	IN
cord-004222-z4butywi	66	19	the	the	DT
cord-004222-z4butywi	66	20	quantification	quantification	NN
cord-004222-z4butywi	66	21	of	of	IN
cord-004222-z4butywi	66	22	differences	difference	NNS
cord-004222-z4butywi	66	23	in	in	IN
cord-004222-z4butywi	66	24	features	feature	NNS
cord-004222-z4butywi	66	25	of	of	IN
cord-004222-z4butywi	66	26	heavy	heavy	JJ
cord-004222-z4butywi	66	27	chain	chain	NN
cord-004222-z4butywi	66	28	VDJ	VDJ	NNP
cord-004222-z4butywi	66	29	recombination	recombination	NN
cord-004222-z4butywi	66	30	and	and	CC
cord-004222-z4butywi	66	31	generated	generate	VBD
cord-004222-z4butywi	66	32	1,000,000	1,000,000	CD
cord-004222-z4butywi	66	33	synthetic	synthetic	JJ
cord-004222-z4butywi	66	34	sequences	sequence	NNS
cord-004222-z4butywi	66	35	per	per	IN
cord-004222-z4butywi	66	36	model	model	NN
cord-004222-z4butywi	66	37	.	.	.
cord-004222-z4butywi	67	1	CDRH3	cdrh3	NN
cord-004222-z4butywi	67	2	length	length	NN
cord-004222-z4butywi	67	3	,	,	,
cord-004222-z4butywi	67	4	VD	VD	NNP
cord-004222-z4butywi	67	5	insertion	insertion	NN
cord-004222-z4butywi	67	6	length	length	NN
cord-004222-z4butywi	67	7	and	and	CC
cord-004222-z4butywi	67	8	DJ	DJ	NNP
cord-004222-z4butywi	67	9	insertion	insertion	NN
cord-004222-z4butywi	67	10	length	length	NN
cord-004222-z4butywi	67	11	distributions	distribution	NNS
cord-004222-z4butywi	67	12	from	from	IN
cord-004222-z4butywi	67	13	the	the	DT
cord-004222-z4butywi	67	14	synthetic	synthetic	JJ
cord-004222-z4butywi	67	15	sequence	sequence	NN
cord-004222-z4butywi	67	16	data	datum	NNS
cord-004222-z4butywi	67	17	(	(	-LRB-
cord-004222-z4butywi	67	18	Fig	Fig	NNP
cord-004222-z4butywi	67	19	.	.	.
cord-004222-z4butywi	67	20	S4a	s4a	JJ
cord-004222-z4butywi	67	21	-	-	HYPH
cord-004222-z4butywi	67	22	c	c	NN
cord-004222-z4butywi	67	23	)	)	-RRB-
cord-004222-z4butywi	67	24	were	be	VBD
cord-004222-z4butywi	67	25	found	find	VBN
cord-004222-z4butywi	67	26	to	to	TO
cord-004222-z4butywi	67	27	be	be	VB
cord-004222-z4butywi	67	28	very	very	RB
cord-004222-z4butywi	67	29	similar	similar	JJ
cord-004222-z4butywi	67	30	to	to	IN
cord-004222-z4butywi	67	31	the	the	DT
cord-004222-z4butywi	67	32	observed	observed	JJ
cord-004222-z4butywi	67	33	data	datum	NNS
cord-004222-z4butywi	67	34	Columns	column	NNS
cord-004222-z4butywi	67	35	are	be	VBP
cord-004222-z4butywi	67	36	antibody	antibody	NN
cord-004222-z4butywi	67	37	repertoires	repertoire	NNS
cord-004222-z4butywi	67	38	and	and	CC
cord-004222-z4butywi	67	39	rows	row	NNS
cord-004222-z4butywi	67	40	are	be	VBP
cord-004222-z4butywi	67	41	gene	gene	NN
cord-004222-z4butywi	67	42	segments	segment	NNS
cord-004222-z4butywi	67	43	.	.	.
cord-004222-z4butywi	68	1	Data	datum	NNS
cord-004222-z4butywi	68	2	was	be	VBD
cord-004222-z4butywi	68	3	scaled	scale	VBN
cord-004222-z4butywi	68	4	by	by	IN
cord-004222-z4butywi	68	5	calculating	calculate	VBG
cord-004222-z4butywi	68	6	the	the	DT
cord-004222-z4butywi	68	7	Z	z	NN
cord-004222-z4butywi	68	8	-	-	HYPH
cord-004222-z4butywi	68	9	score	score	NN
cord-004222-z4butywi	68	10	for	for	IN
cord-004222-z4butywi	68	11	each	each	DT
cord-004222-z4butywi	68	12	gene	gene	NN
cord-004222-z4butywi	68	13	(	(	-LRB-
cord-004222-z4butywi	68	14	row	row	NN
cord-004222-z4butywi	68	15	)	)	-RRB-
cord-004222-z4butywi	68	16	and	and	CC
cord-004222-z4butywi	68	17	hierarchical	hierarchical	JJ
cord-004222-z4butywi	68	18	clustering	clustering	NN
cord-004222-z4butywi	68	19	(	(	-LRB-
cord-004222-z4butywi	68	20	Euclidean	euclidean	JJ
cord-004222-z4butywi	68	21	distance	distance	NN
cord-004222-z4butywi	68	22	metric	metric	NN
cord-004222-z4butywi	68	23	)	)	-RRB-
cord-004222-z4butywi	68	24	was	be	VBD
cord-004222-z4butywi	68	25	done	do	VBN
cord-004222-z4butywi	68	26	.	.	.
cord-004222-z4butywi	69	1	A	a	DT
cord-004222-z4butywi	69	2	dendrogram	dendrogram	JJ
cord-004222-z4butywi	69	3	representation	representation	NN
cord-004222-z4butywi	69	4	of	of	IN
cord-004222-z4butywi	69	5	clustering	clustering	NN
cord-004222-z4butywi	69	6	is	be	VBZ
cord-004222-z4butywi	69	7	shown	show	VBN
cord-004222-z4butywi	69	8	and	and	CC
cord-004222-z4butywi	69	9	indicates	indicate	VBZ
cord-004222-z4butywi	69	10	uniqueness	uniqueness	NN
cord-004222-z4butywi	69	11	in	in	IN
cord-004222-z4butywi	69	12	gene	gene	NN
cord-004222-z4butywi	69	13	segment	segment	NN
cord-004222-z4butywi	69	14	usage	usage	NN
cord-004222-z4butywi	69	15	between	between	IN
cord-004222-z4butywi	69	16	the	the	DT
cord-004222-z4butywi	69	17	lymph	lymph	NN
cord-004222-z4butywi	69	18	node	node	NN
cord-004222-z4butywi	69	19	and	and	CC
cord-004222-z4butywi	69	20	spleen	spleen	NN
cord-004222-z4butywi	69	21	repertoires	repertoire	NNS
cord-004222-z4butywi	69	22	of	of	IN
cord-004222-z4butywi	69	23	the	the	DT
cord-004222-z4butywi	69	24	OmniRat	OmniRat	NNP
cord-004222-z4butywi	69	25	and	and	CC
cord-004222-z4butywi	69	26	between	between	IN
cord-004222-z4butywi	69	27	the	the	DT
cord-004222-z4butywi	69	28	OmniRat	omnirat	NN
cord-004222-z4butywi	69	29	and	and	CC
cord-004222-z4butywi	69	30	human	human	JJ
cord-004222-z4butywi	69	31	repertoires	repertoire	NNS
cord-004222-z4butywi	69	32	.	.	.
cord-004222-z4butywi	70	1	Red	red	JJ
cord-004222-z4butywi	70	2	and	and	CC
cord-004222-z4butywi	70	3	blue	blue	JJ
cord-004222-z4butywi	70	4	indicate	indicate	VBP
cord-004222-z4butywi	70	5	high	high	JJ
cord-004222-z4butywi	70	6	and	and	CC
cord-004222-z4butywi	70	7	low	low	JJ
cord-004222-z4butywi	70	8	Z	z	NN
cord-004222-z4butywi	70	9	-	-	HYPH
cord-004222-z4butywi	70	10	scores	score	NNS
cord-004222-z4butywi	70	11	respectively	respectively	RB
cord-004222-z4butywi	71	1	(	(	-LRB-
cord-004222-z4butywi	71	2	legend	legend	NN
cord-004222-z4butywi	71	3	shown	show	VBN
cord-004222-z4butywi	71	4	in	in	IN
cord-004222-z4butywi	71	5	a	a	DT
cord-004222-z4butywi	71	6	)	)	-RRB-
cord-004222-z4butywi	71	7	,	,	,
cord-004222-z4butywi	71	8	and	and	CC
cord-004222-z4butywi	71	9	since	since	IN
cord-004222-z4butywi	71	10	it	-PRON-	PRP
cord-004222-z4butywi	71	11	is	be	VBZ
cord-004222-z4butywi	71	12	calculated	calculate	VBN
cord-004222-z4butywi	71	13	per	per	IN
cord-004222-z4butywi	71	14	gene	gene	NN
cord-004222-z4butywi	71	15	it	-PRON-	PRP
cord-004222-z4butywi	71	16	represents	represent	VBZ
cord-004222-z4butywi	71	17	differences	difference	NNS
cord-004222-z4butywi	71	18	between	between	IN
cord-004222-z4butywi	71	19	repertoires	repertoire	NNS
cord-004222-z4butywi	71	20	and	and	CC
cord-004222-z4butywi	71	21	not	not	RB
cord-004222-z4butywi	71	22	the	the	DT
cord-004222-z4butywi	71	23	relative	relative	JJ
cord-004222-z4butywi	71	24	frequencies	frequency	NNS
cord-004222-z4butywi	71	25	of	of	IN
cord-004222-z4butywi	71	26	gene	gene	NN
cord-004222-z4butywi	71	27	segment	segment	NN
cord-004222-z4butywi	71	28	usage	usage	NN
cord-004222-z4butywi	71	29	in	in	IN
cord-004222-z4butywi	71	30	each	each	DT
cord-004222-z4butywi	71	31	repertoire	repertoire	NN
cord-004222-z4butywi	71	32	.	.	.
cord-004222-z4butywi	72	1	(	(	-LRB-
cord-004222-z4butywi	72	2	Fig	Fig	NNP
cord-004222-z4butywi	72	3	.	.	.
cord-004222-z4butywi	72	4	2a	2a	CD
cord-004222-z4butywi	72	5	-	-	HYPH
cord-004222-z4butywi	72	6	c	c	NN
cord-004222-z4butywi	72	7	)	)	-RRB-
cord-004222-z4butywi	72	8	.	.	.
cord-004222-z4butywi	73	1	Kullback	Kullback	NNP
cord-004222-z4butywi	73	2	-	-	HYPH
cord-004222-z4butywi	73	3	Leibler	Leibler	NNP
cord-004222-z4butywi	73	4	(	(	-LRB-
cord-004222-z4butywi	73	5	KL	KL	NNP
cord-004222-z4butywi	73	6	)	)	-RRB-
cord-004222-z4butywi	73	7	divergence	divergence	NN
cord-004222-z4butywi	73	8	is	be	VBZ
cord-004222-z4butywi	73	9	a	a	DT
cord-004222-z4butywi	73	10	measure	measure	NN
cord-004222-z4butywi	73	11	of	of	IN
cord-004222-z4butywi	73	12	how	how	WRB
cord-004222-z4butywi	73	13	different	different	JJ
cord-004222-z4butywi	73	14	two	two	CD
cord-004222-z4butywi	73	15	probability	probability	NN
cord-004222-z4butywi	73	16	distributions	distribution	NNS
cord-004222-z4butywi	73	17	are	be	VBP
cord-004222-z4butywi	73	18	.	.	.
cord-004222-z4butywi	74	1	KL	KL	NNP
cord-004222-z4butywi	74	2	divergence	divergence	NN
cord-004222-z4butywi	74	3	between	between	IN
cord-004222-z4butywi	74	4	models	model	NNS
cord-004222-z4butywi	74	5	(	(	-LRB-
cord-004222-z4butywi	74	6	Fig	fig	NN
cord-004222-z4butywi	74	7	.	.	.
cord-004222-z4butywi	74	8	S4d	S4d	NNP
cord-004222-z4butywi	74	9	)	)	-RRB-
cord-004222-z4butywi	74	10	and	and	CC
cord-004222-z4butywi	74	11	model	model	NN
cord-004222-z4butywi	74	12	'	'	``
cord-004222-z4butywi	74	13	events	event	NNS
cord-004222-z4butywi	74	14	'	'	''
cord-004222-z4butywi	74	15	(	(	-LRB-
cord-004222-z4butywi	74	16	Fig	Fig	NNP
cord-004222-z4butywi	74	17	.	.	.
cord-004222-z4butywi	74	18	S4e	s4e	NN
cord-004222-z4butywi	74	19	)	)	-RRB-
cord-004222-z4butywi	74	20	were	be	VBD
cord-004222-z4butywi	74	21	computed	compute	VBN
cord-004222-z4butywi	74	22	as	as	IN
cord-004222-z4butywi	74	23	previously	previously	RB
cord-004222-z4butywi	74	24	described	describe	VBN
cord-004222-z4butywi	74	25	13	13	CD
cord-004222-z4butywi	74	26	.	.	.
cord-004222-z4butywi	75	1	KL	KL	NNP
cord-004222-z4butywi	75	2	divergence	divergence	NN
cord-004222-z4butywi	75	3	between	between	IN
cord-004222-z4butywi	75	4	pairs	pair	NNS
cord-004222-z4butywi	75	5	of	of	IN
cord-004222-z4butywi	75	6	OmniRat	OmniRat	NNP
cord-004222-z4butywi	75	7	models	model	NNS
cord-004222-z4butywi	75	8	was	be	VBD
cord-004222-z4butywi	75	9	found	find	VBN
cord-004222-z4butywi	75	10	to	to	TO
cord-004222-z4butywi	75	11	be	be	VB
cord-004222-z4butywi	75	12	lower	low	JJR
cord-004222-z4butywi	75	13	than	than	IN
cord-004222-z4butywi	75	14	KL	KL	NNP
cord-004222-z4butywi	75	15	divergence	divergence	NN
cord-004222-z4butywi	75	16	between	between	IN
cord-004222-z4butywi	75	17	pairs	pair	NNS
cord-004222-z4butywi	75	18	of	of	IN
cord-004222-z4butywi	75	19	human	human	JJ
cord-004222-z4butywi	75	20	models	model	NNS
cord-004222-z4butywi	75	21	for	for	IN
cord-004222-z4butywi	75	22	both	both	CC
cord-004222-z4butywi	75	23	complete	complete	JJ
cord-004222-z4butywi	75	24	and	and	CC
cord-004222-z4butywi	75	25	all	all	DT
cord-004222-z4butywi	75	26	event	event	NN
cord-004222-z4butywi	75	27	level	level	NN
cord-004222-z4butywi	75	28	calculations	calculation	NNS
cord-004222-z4butywi	75	29	.	.	.
cord-004222-z4butywi	76	1	The	the	DT
cord-004222-z4butywi	76	2	average	average	JJ
cord-004222-z4butywi	76	3	pairwise	pairwise	JJ
cord-004222-z4butywi	76	4	OmniRat	omnirat	NN
cord-004222-z4butywi	76	5	model	model	NN
cord-004222-z4butywi	76	6	versus	versus	IN
cord-004222-z4butywi	76	7	human	human	JJ
cord-004222-z4butywi	76	8	model	model	NN
cord-004222-z4butywi	76	9	complete	complete	JJ
cord-004222-z4butywi	76	10	KL	KL	NNP
cord-004222-z4butywi	76	11	divergence	divergence	NN
cord-004222-z4butywi	76	12	calculation	calculation	NN
cord-004222-z4butywi	76	13	was	be	VBD
cord-004222-z4butywi	76	14	found	find	VBN
cord-004222-z4butywi	76	15	to	to	TO
cord-004222-z4butywi	76	16	be	be	VB
cord-004222-z4butywi	76	17	much	much	RB
cord-004222-z4butywi	76	18	greater	great	JJR
cord-004222-z4butywi	76	19	than	than	IN
cord-004222-z4butywi	76	20	that	that	DT
cord-004222-z4butywi	76	21	of	of	IN
cord-004222-z4butywi	76	22	pairwise	pairwise	JJ
cord-004222-z4butywi	76	23	inter	inter	JJ
cord-004222-z4butywi	76	24	-	-	JJ
cord-004222-z4butywi	76	25	animal	animal	JJ
cord-004222-z4butywi	76	26	calculations	calculation	NNS
cord-004222-z4butywi	76	27	and	and	CC
cord-004222-z4butywi	76	28	more	more	JJR
cord-004222-z4butywi	76	29	than	than	IN
cord-004222-z4butywi	76	30	twice	twice	PDT
cord-004222-z4butywi	76	31	that	that	DT
cord-004222-z4butywi	76	32	of	of	IN
cord-004222-z4butywi	76	33	pairwise	pairwise	JJ
cord-004222-z4butywi	76	34	inter	inter	JJ
cord-004222-z4butywi	76	35	-	-	JJ
cord-004222-z4butywi	76	36	human	human	JJ
cord-004222-z4butywi	76	37	calculations	calculation	NNS
cord-004222-z4butywi	76	38	.	.	.
cord-004222-z4butywi	77	1	"	"	''
cord-004222-z4butywi	78	1	D	D	NNP
cord-004222-z4butywi	78	2	-	-	HYPH
cord-004222-z4butywi	78	3	Gene	Gene	NNP
cord-004222-z4butywi	78	4	"	"	''
cord-004222-z4butywi	78	5	,	,	,
cord-004222-z4butywi	78	6	"	"	''
cord-004222-z4butywi	78	7	V	v	NN
cord-004222-z4butywi	78	8	-	-	HYPH
cord-004222-z4butywi	78	9	gene	gene	NN
cord-004222-z4butywi	78	10	trim	trim	NN
cord-004222-z4butywi	78	11	(	(	-LRB-
cord-004222-z4butywi	78	12	3	3	CD
cord-004222-z4butywi	78	13	'	'	''
cord-004222-z4butywi	78	14	)	)	-RRB-
cord-004222-z4butywi	78	15	"	"	''
cord-004222-z4butywi	78	16	,	,	,
cord-004222-z4butywi	78	17	and	and	CC
cord-004222-z4butywi	78	18	"	"	``
cord-004222-z4butywi	78	19	D	d	NN
cord-004222-z4butywi	78	20	-	-	HYPH
cord-004222-z4butywi	78	21	gene	gene	NN
cord-004222-z4butywi	78	22	trim	trim	NN
cord-004222-z4butywi	78	23	(	(	-LRB-
cord-004222-z4butywi	78	24	3	3	CD
cord-004222-z4butywi	78	25	'	'	''
cord-004222-z4butywi	78	26	)	)	-RRB-
cord-004222-z4butywi	79	1	"	"	``
cord-004222-z4butywi	79	2	were	be	VBD
cord-004222-z4butywi	79	3	among	among	IN
cord-004222-z4butywi	79	4	the	the	DT
cord-004222-z4butywi	79	5	events	event	NNS
cord-004222-z4butywi	79	6	computed	compute	VBN
cord-004222-z4butywi	79	7	to	to	TO
cord-004222-z4butywi	79	8	have	have	VB
cord-004222-z4butywi	79	9	the	the	DT
cord-004222-z4butywi	79	10	mean	mean	JJ
cord-004222-z4butywi	79	11	highest	high	JJS
cord-004222-z4butywi	79	12	KL	KL	NNP
cord-004222-z4butywi	79	13	divergence	divergence	NN
cord-004222-z4butywi	79	14	from	from	IN
cord-004222-z4butywi	79	15	pairwise	pairwise	JJ
cord-004222-z4butywi	79	16	inter	inter	JJ
cord-004222-z4butywi	79	17	-	-	JJ
cord-004222-z4butywi	79	18	species	species	JJ
cord-004222-z4butywi	79	19	event	event	NN
cord-004222-z4butywi	79	20	level	level	NN
cord-004222-z4butywi	79	21	model	model	NN
cord-004222-z4butywi	79	22	comparisons	comparison	NNS
cord-004222-z4butywi	79	23	.	.	.
cord-004222-z4butywi	80	1	Class	class	NN
cord-004222-z4butywi	80	2	switch	switch	NN
cord-004222-z4butywi	80	3	recombination	recombination	NN
cord-004222-z4butywi	80	4	and	and	CC
cord-004222-z4butywi	80	5	somatic	somatic	JJ
cord-004222-z4butywi	80	6	hypermutation	hypermutation	NN
cord-004222-z4butywi	80	7	in	in	IN
cord-004222-z4butywi	80	8	OmniRats	OmniRats	NNP
cord-004222-z4butywi	80	9	.	.	.
cord-004222-z4butywi	81	1	In	in	IN
cord-004222-z4butywi	81	2	Supplementary	Supplementary	NNP
cord-004222-z4butywi	81	3	Fig	Fig	NNP
cord-004222-z4butywi	81	4	.	.	.
cord-004222-z4butywi	82	1	S5a	s5a	JJ
cord-004222-z4butywi	82	2	,	,	,
cord-004222-z4butywi	82	3	the	the	DT
cord-004222-z4butywi	82	4	frequency	frequency	NN
cord-004222-z4butywi	82	5	of	of	IN
cord-004222-z4butywi	82	6	antibody	antibody	NN
cord-004222-z4butywi	82	7	isotypes	isotypes	NNP
cord-004222-z4butywi	82	8	is	be	VBZ
cord-004222-z4butywi	82	9	shown	show	VBN
cord-004222-z4butywi	82	10	.	.	.
cord-004222-z4butywi	83	1	The	the	DT
cord-004222-z4butywi	83	2	human	human	JJ
cord-004222-z4butywi	83	3	repertoire	repertoire	NN
cord-004222-z4butywi	83	4	contains	contain	VBZ
cord-004222-z4butywi	83	5	average	average	JJ
cord-004222-z4butywi	83	6	frequencies	frequency	NNS
cord-004222-z4butywi	83	7	of	of	IN
cord-004222-z4butywi	83	8	0.84	0.84	CD
cord-004222-z4butywi	83	9	and	and	CC
cord-004222-z4butywi	83	10	0.16	0.16	CD
cord-004222-z4butywi	83	11	for	for	IN
cord-004222-z4butywi	83	12	IgM	IgM	NNP
cord-004222-z4butywi	83	13	and	and	CC
cord-004222-z4butywi	83	14	IgG	IgG	NNP
cord-004222-z4butywi	83	15	respectively	respectively	RB
cord-004222-z4butywi	83	16	as	as	IN
cord-004222-z4butywi	83	17	previously	previously	RB
cord-004222-z4butywi	83	18	published	publish	VBN
cord-004222-z4butywi	83	19	13	13	CD
cord-004222-z4butywi	83	20	,	,	,
cord-004222-z4butywi	83	21	while	while	IN
cord-004222-z4butywi	83	22	in	in	IN
cord-004222-z4butywi	83	23	the	the	DT
cord-004222-z4butywi	83	24	OmniRat	OmniRat	NNP
cord-004222-z4butywi	83	25	antibody	antibody	NN
cord-004222-z4butywi	83	26	repertoire	repertoire	NN
cord-004222-z4butywi	83	27	we	-PRON-	PRP
cord-004222-z4butywi	83	28	observe	observe	VBP
cord-004222-z4butywi	83	29	mean	mean	JJ
cord-004222-z4butywi	83	30	frequencies	frequency	NNS
cord-004222-z4butywi	83	31	of	of	IN
cord-004222-z4butywi	83	32	0.15	0.15	CD
cord-004222-z4butywi	83	33	and	and	CC
cord-004222-z4butywi	83	34	0.003	0.003	CD
cord-004222-z4butywi	83	35	for	for	IN
cord-004222-z4butywi	83	36	lymph	lymph	NN
cord-004222-z4butywi	83	37	node	node	NN
cord-004222-z4butywi	83	38	and	and	CC
cord-004222-z4butywi	83	39	spleen	spleen	NN
cord-004222-z4butywi	83	40	IgG	IgG	NNP
cord-004222-z4butywi	83	41	respectively	respectively	RB
cord-004222-z4butywi	83	42	and	and	CC
cord-004222-z4butywi	83	43	means	mean	NNS
cord-004222-z4butywi	83	44	of	of	IN
cord-004222-z4butywi	83	45	0.85	0.85	CD
cord-004222-z4butywi	83	46	and	and	CC
cord-004222-z4butywi	83	47	0.997	0.997	CD
cord-004222-z4butywi	83	48	for	for	IN
cord-004222-z4butywi	83	49	lymph	lymph	NN
cord-004222-z4butywi	83	50	node	node	NN
cord-004222-z4butywi	83	51	and	and	CC
cord-004222-z4butywi	83	52	spleen	spleen	NN
cord-004222-z4butywi	83	53	IgM	IgM	NNP
cord-004222-z4butywi	83	54	respectively	respectively	RB
cord-004222-z4butywi	83	55	.	.	.
cord-004222-z4butywi	84	1	Mean	mean	JJ
cord-004222-z4butywi	84	2	numbers	number	NNS
cord-004222-z4butywi	84	3	of	of	IN
cord-004222-z4butywi	84	4	variable	variable	JJ
cord-004222-z4butywi	84	5	gene	gene	NN
cord-004222-z4butywi	84	6	mutations	mutation	NNS
cord-004222-z4butywi	84	7	in	in	IN
cord-004222-z4butywi	84	8	IgM	IgM	NNP
cord-004222-z4butywi	84	9	(	(	-LRB-
cord-004222-z4butywi	84	10	Fig	Fig	NNP
cord-004222-z4butywi	84	11	.	.	.
cord-004222-z4butywi	84	12	S5b	S5b	NNP
cord-004222-z4butywi	84	13	)	)	-RRB-
cord-004222-z4butywi	84	14	,	,	,
cord-004222-z4butywi	84	15	IgG	IgG	NNP
cord-004222-z4butywi	84	16	(	(	-LRB-
cord-004222-z4butywi	84	17	Fig	Fig	NNP
cord-004222-z4butywi	84	18	.	.	.
cord-004222-z4butywi	84	19	S5c	S5c	NNP
cord-004222-z4butywi	84	20	)	)	-RRB-
cord-004222-z4butywi	84	21	and	and	CC
cord-004222-z4butywi	84	22	kappa	kappa	NNP
cord-004222-z4butywi	84	23	(	(	-LRB-
cord-004222-z4butywi	84	24	Fig	Fig	NNP
cord-004222-z4butywi	84	25	.	.	.
cord-004222-z4butywi	84	26	S6d	s6d	NN
cord-004222-z4butywi	84	27	)	)	-RRB-
cord-004222-z4butywi	85	1	sequences	sequence	NNS
cord-004222-z4butywi	85	2	of	of	IN
cord-004222-z4butywi	85	3	the	the	DT
cord-004222-z4butywi	85	4	OmniRat	OmniRat	NNP
cord-004222-z4butywi	85	5	were	be	VBD
cord-004222-z4butywi	85	6	about	about	RB
cord-004222-z4butywi	85	7	half	half	NN
cord-004222-z4butywi	85	8	of	of	IN
cord-004222-z4butywi	85	9	those	those	DT
cord-004222-z4butywi	85	10	found	find	VBN
cord-004222-z4butywi	85	11	in	in	IN
cord-004222-z4butywi	85	12	the	the	DT
cord-004222-z4butywi	85	13	human	human	JJ
cord-004222-z4butywi	85	14	repertoire	repertoire	NN
cord-004222-z4butywi	85	15	.	.	.
cord-004222-z4butywi	86	1	The	the	DT
cord-004222-z4butywi	86	2	observed	observed	JJ
cord-004222-z4butywi	86	3	increase	increase	NN
cord-004222-z4butywi	86	4	in	in	IN
cord-004222-z4butywi	86	5	SHM	SHM	NNP
cord-004222-z4butywi	86	6	of	of	IN
cord-004222-z4butywi	86	7	class	class	NN
cord-004222-z4butywi	86	8	-	-	HYPH
cord-004222-z4butywi	86	9	switched	switch	VBN
cord-004222-z4butywi	86	10	IgG	igg	NN
cord-004222-z4butywi	86	11	sequences	sequence	NNS
cord-004222-z4butywi	86	12	as	as	IN
cord-004222-z4butywi	86	13	compared	compare	VBN
cord-004222-z4butywi	86	14	to	to	IN
cord-004222-z4butywi	86	15	IgM	IgM	NNP
cord-004222-z4butywi	86	16	sequences	sequence	NNS
cord-004222-z4butywi	86	17	in	in	IN
cord-004222-z4butywi	86	18	the	the	DT
cord-004222-z4butywi	86	19	OmniRat	OmniRat	NNP
cord-004222-z4butywi	86	20	demonstrates	demonstrate	VBZ
cord-004222-z4butywi	86	21	the	the	DT
cord-004222-z4butywi	86	22	ability	ability	NN
cord-004222-z4butywi	86	23	of	of	IN
cord-004222-z4butywi	86	24	the	the	DT
cord-004222-z4butywi	86	25	animal	animal	NN
cord-004222-z4butywi	86	26	to	to	TO
cord-004222-z4butywi	86	27	generate	generate	VB
cord-004222-z4butywi	86	28	memory	memory	NN
cord-004222-z4butywi	86	29	B	b	NN
cord-004222-z4butywi	86	30	cells	cell	NNS
cord-004222-z4butywi	86	31	.	.	.
cord-004222-z4butywi	87	1	We	-PRON-	PRP
cord-004222-z4butywi	87	2	first	first	RB
cord-004222-z4butywi	87	3	examined	examine	VBD
cord-004222-z4butywi	87	4	clonotype	clonotype	NN
cord-004222-z4butywi	87	5	(	(	-LRB-
cord-004222-z4butywi	87	6	defined	define	VBN
cord-004222-z4butywi	87	7	as	as	IN
cord-004222-z4butywi	87	8	identical	identical	JJ
cord-004222-z4butywi	87	9	VH	VH	NNP
cord-004222-z4butywi	87	10	gene	gene	NN
cord-004222-z4butywi	87	11	,	,	,
cord-004222-z4butywi	87	12	JH	JH	NNP
cord-004222-z4butywi	87	13	gene	gene	NN
cord-004222-z4butywi	87	14	and	and	CC
cord-004222-z4butywi	87	15	CDRH3	cdrh3	NN
cord-004222-z4butywi	87	16	amino	amino	NN
cord-004222-z4butywi	87	17	acid	acid	NN
cord-004222-z4butywi	87	18	sequence	sequence	NN
cord-004222-z4butywi	87	19	)	)	-RRB-
cord-004222-z4butywi	87	20	diversity	diversity	NN
cord-004222-z4butywi	87	21	of	of	IN
cord-004222-z4butywi	87	22	the	the	DT
cord-004222-z4butywi	87	23	heavy	heavy	JJ
cord-004222-z4butywi	87	24	chain	chain	NN
cord-004222-z4butywi	87	25	repertoire	repertoire	NN
cord-004222-z4butywi	87	26	for	for	IN
cord-004222-z4butywi	87	27	each	each	DT
cord-004222-z4butywi	87	28	individual	individual	JJ
cord-004222-z4butywi	87	29	animal	animal	NN
cord-004222-z4butywi	87	30	.	.	.
cord-004222-z4butywi	88	1	All	all	DT
cord-004222-z4butywi	88	2	sequences	sequence	NNS
cord-004222-z4butywi	88	3	from	from	IN
cord-004222-z4butywi	88	4	lymph	lymph	NN
cord-004222-z4butywi	88	5	nodes	node	NNS
cord-004222-z4butywi	88	6	and	and	CC
cord-004222-z4butywi	88	7	spleens	spleen	NNS
cord-004222-z4butywi	88	8	were	be	VBD
cord-004222-z4butywi	88	9	collapsed	collapse	VBN
cord-004222-z4butywi	88	10	into	into	IN
cord-004222-z4butywi	88	11	unique	unique	JJ
cord-004222-z4butywi	88	12	clonotypes	clonotype	NNS
cord-004222-z4butywi	88	13	,	,	,
cord-004222-z4butywi	88	14	separately	separately	RB
cord-004222-z4butywi	88	15	for	for	IN
cord-004222-z4butywi	88	16	each	each	DT
cord-004222-z4butywi	88	17	tissue	tissue	NN
cord-004222-z4butywi	88	18	and	and	CC
cord-004222-z4butywi	88	19	animal	animal	NN
cord-004222-z4butywi	88	20	.	.	.
cord-004222-z4butywi	89	1	Any	any	DT
cord-004222-z4butywi	89	2	clonotype	clonotype	NN
cord-004222-z4butywi	89	3	found	find	VBD
cord-004222-z4butywi	89	4	in	in	IN
cord-004222-z4butywi	89	5	both	both	DT
cord-004222-z4butywi	89	6	tissue	tissue	NN
cord-004222-z4butywi	89	7	compartments	compartment	NNS
cord-004222-z4butywi	89	8	must	must	MD
cord-004222-z4butywi	89	9	have	have	VB
cord-004222-z4butywi	89	10	originated	originate	VBN
cord-004222-z4butywi	89	11	from	from	IN
cord-004222-z4butywi	89	12	different	different	JJ
cord-004222-z4butywi	89	13	B	b	NN
cord-004222-z4butywi	89	14	cells	cell	NNS
cord-004222-z4butywi	89	15	,	,	,
cord-004222-z4butywi	89	16	allowing	allow	VBG
cord-004222-z4butywi	89	17	for	for	IN
cord-004222-z4butywi	89	18	the	the	DT
cord-004222-z4butywi	89	19	measurement	measurement	NN
cord-004222-z4butywi	89	20	of	of	IN
cord-004222-z4butywi	89	21	repeatedly	repeatedly	RB
cord-004222-z4butywi	89	22	observed	observe	VBD
cord-004222-z4butywi	89	23	clonotypes	clonotype	NNS
cord-004222-z4butywi	89	24	.	.	.
cord-004222-z4butywi	90	1	Rarefaction	rarefaction	NN
cord-004222-z4butywi	90	2	curves	curve	NNS
cord-004222-z4butywi	90	3	for	for	IN
cord-004222-z4butywi	90	4	each	each	DT
cord-004222-z4butywi	90	5	animal	animal	NN
cord-004222-z4butywi	90	6	were	be	VBD
cord-004222-z4butywi	90	7	www.nature.com/scientificreports	www.nature.com/scientificreport	NNS
cord-004222-z4butywi	91	1	www.nature.com/scientificreports/	www.nature.com/scientificreports/	NNP
cord-004222-z4butywi	91	2	generated	generate	VBD
cord-004222-z4butywi	91	3	(	(	-LRB-
cord-004222-z4butywi	91	4	Fig	Fig	NNP
cord-004222-z4butywi	91	5	.	.	.
cord-004222-z4butywi	91	6	3a	3a	NNP
cord-004222-z4butywi	91	7	)	)	-RRB-
cord-004222-z4butywi	91	8	and	and	CC
cord-004222-z4butywi	91	9	indicate	indicate	VBP
cord-004222-z4butywi	91	10	a	a	DT
cord-004222-z4butywi	91	11	low	low	JJ
cord-004222-z4butywi	91	12	frequency	frequency	NN
cord-004222-z4butywi	91	13	of	of	IN
cord-004222-z4butywi	91	14	repeatedly	repeatedly	RB
cord-004222-z4butywi	91	15	observed	observe	VBD
cord-004222-z4butywi	91	16	clonotypes	clonotype	NNS
cord-004222-z4butywi	91	17	.	.	.
cord-004222-z4butywi	92	1	We	-PRON-	PRP
cord-004222-z4butywi	92	2	estimated	estimate	VBD
cord-004222-z4butywi	92	3	diversity	diversity	NN
cord-004222-z4butywi	92	4	using	use	VBG
cord-004222-z4butywi	92	5	Chao	Chao	NNP
cord-004222-z4butywi	92	6	2	2	CD
cord-004222-z4butywi	92	7	22	22	CD
cord-004222-z4butywi	92	8	,	,	,
cord-004222-z4butywi	92	9	23	23	CD
cord-004222-z4butywi	92	10	and	and	CC
cord-004222-z4butywi	92	11	Recon	Recon	NNP
cord-004222-z4butywi	92	12	23,24	23,24	CD
cord-004222-z4butywi	92	13	as	as	IN
cord-004222-z4butywi	92	14	previously	previously	RB
cord-004222-z4butywi	92	15	described	describe	VBN
cord-004222-z4butywi	92	16	13	13	CD
cord-004222-z4butywi	92	17	.	.	.
cord-004222-z4butywi	93	1	Diversity	diversity	NN
cord-004222-z4butywi	93	2	estimates	estimate	NNS
cord-004222-z4butywi	93	3	were	be	VBD
cord-004222-z4butywi	93	4	similar	similar	JJ
cord-004222-z4butywi	93	5	between	between	IN
cord-004222-z4butywi	93	6	the	the	DT
cord-004222-z4butywi	93	7	two	two	CD
cord-004222-z4butywi	93	8	estimators	estimator	NNS
cord-004222-z4butywi	93	9	,	,	,
cord-004222-z4butywi	93	10	(	(	-LRB-
cord-004222-z4butywi	93	11	4.8	4.8	CD
cord-004222-z4butywi	93	12	×	×	NN
cord-004222-z4butywi	93	13	10	10	CD
cord-004222-z4butywi	93	14	6	6	CD
cord-004222-z4butywi	93	15	-7.4	-7.4	CD
cord-004222-z4butywi	93	16	×	×	NNP
cord-004222-z4butywi	93	17	10	10	CD
cord-004222-z4butywi	93	18	6	6	CD
cord-004222-z4butywi	93	19	)	)	-RRB-
cord-004222-z4butywi	93	20	for	for	IN
cord-004222-z4butywi	93	21	Chao	Chao	NNP
cord-004222-z4butywi	93	22	and	and	CC
cord-004222-z4butywi	93	23	(	(	-LRB-
cord-004222-z4butywi	93	24	9.4	9.4	CD
cord-004222-z4butywi	93	25	×	×	NN
cord-004222-z4butywi	93	26	10	10	CD
cord-004222-z4butywi	93	27	6	6	CD
cord-004222-z4butywi	93	28	-1.9	-1.9	CD
cord-004222-z4butywi	93	29	×	×	NN
cord-004222-z4butywi	93	30	10	10	CD
cord-004222-z4butywi	93	31	7	7	CD
cord-004222-z4butywi	93	32	)	)	-RRB-
cord-004222-z4butywi	93	33	for	for	IN
cord-004222-z4butywi	93	34	Recon	Recon	NNP
cord-004222-z4butywi	93	35	(	(	-LRB-
cord-004222-z4butywi	93	36	Fig	Fig	NNP
cord-004222-z4butywi	93	37	.	.	.
cord-004222-z4butywi	93	38	3b	3b	CD
cord-004222-z4butywi	93	39	)	)	-RRB-
cord-004222-z4butywi	93	40	.	.	.
cord-004222-z4butywi	94	1	We	-PRON-	PRP
cord-004222-z4butywi	94	2	next	next	RB
cord-004222-z4butywi	94	3	estimated	estimate	VBD
cord-004222-z4butywi	94	4	heavy	heavy	JJ
cord-004222-z4butywi	94	5	chain	chain	NN
cord-004222-z4butywi	94	6	sequence	sequence	NN
cord-004222-z4butywi	94	7	diversity	diversity	NN
cord-004222-z4butywi	94	8	for	for	IN
cord-004222-z4butywi	94	9	each	each	DT
cord-004222-z4butywi	94	10	animal	animal	NN
cord-004222-z4butywi	95	1	(	(	-LRB-
cord-004222-z4butywi	95	2	Fig	Fig	NNP
cord-004222-z4butywi	95	3	.	.	.
cord-004222-z4butywi	95	4	3c	3c	NNP
cord-004222-z4butywi	95	5	)	)	-RRB-
cord-004222-z4butywi	96	1	and	and	CC
cord-004222-z4butywi	96	2	again	again	RB
cord-004222-z4butywi	96	3	found	find	VBD
cord-004222-z4butywi	96	4	that	that	IN
cord-004222-z4butywi	96	5	both	both	DT
cord-004222-z4butywi	96	6	estimators	estimator	NNS
cord-004222-z4butywi	96	7	broadly	broadly	RB
cord-004222-z4butywi	96	8	agreed	agree	VBD
cord-004222-z4butywi	96	9	,	,	,
cord-004222-z4butywi	96	10	giving	give	VBG
cord-004222-z4butywi	96	11	similar	similar	JJ
cord-004222-z4butywi	96	12	values	value	NNS
cord-004222-z4butywi	96	13	of	of	IN
cord-004222-z4butywi	96	14	(	(	-LRB-
cord-004222-z4butywi	96	15	5.0	5.0	CD
cord-004222-z4butywi	96	16	×	×	NN
cord-004222-z4butywi	96	17	10	10	CD
cord-004222-z4butywi	96	18	7	7	CD
cord-004222-z4butywi	96	19	-8.1	-8.1	NNP
cord-004222-z4butywi	96	20	×	×	NNP
cord-004222-z4butywi	96	21	10	10	CD
cord-004222-z4butywi	96	22	7	7	CD
cord-004222-z4butywi	96	23	)	)	-RRB-
cord-004222-z4butywi	96	24	for	for	IN
cord-004222-z4butywi	96	25	Chao	Chao	NNP
cord-004222-z4butywi	96	26	and	and	CC
cord-004222-z4butywi	96	27	(	(	-LRB-
cord-004222-z4butywi	96	28	5.4	5.4	CD
cord-004222-z4butywi	96	29	×	×	NN
cord-004222-z4butywi	96	30	10	10	CD
cord-004222-z4butywi	96	31	7	7	CD
cord-004222-z4butywi	96	32	-1.0	-1.0	CD
cord-004222-z4butywi	96	33	×	×	NN
cord-004222-z4butywi	96	34	10	10	CD
cord-004222-z4butywi	96	35	8	8	CD
cord-004222-z4butywi	96	36	)	)	-RRB-
cord-004222-z4butywi	96	37	for	for	IN
cord-004222-z4butywi	96	38	Recon	Recon	NNP
cord-004222-z4butywi	96	39	.	.	.
cord-004222-z4butywi	97	1	Previously	previously	RB
cord-004222-z4butywi	97	2	published	publish	VBN
cord-004222-z4butywi	97	3	estimates	estimate	NNS
cord-004222-z4butywi	97	4	of	of	IN
cord-004222-z4butywi	97	5	both	both	DT
cord-004222-z4butywi	97	6	clonotype	clonotype	NN
cord-004222-z4butywi	97	7	and	and	CC
cord-004222-z4butywi	97	8	sequence	sequence	NN
cord-004222-z4butywi	97	9	diversity	diversity	NN
cord-004222-z4butywi	97	10	in	in	IN
cord-004222-z4butywi	97	11	individual	individual	JJ
cord-004222-z4butywi	97	12	humans	human	NNS
cord-004222-z4butywi	97	13	17	17	CD
cord-004222-z4butywi	97	14	only	only	RB
cord-004222-z4butywi	97	15	exceed	exceed	VBP
cord-004222-z4butywi	97	16	that	that	DT
cord-004222-z4butywi	97	17	in	in	IN
cord-004222-z4butywi	97	18	the	the	DT
cord-004222-z4butywi	97	19	OmniRats	OmniRats	NNP
cord-004222-z4butywi	97	20	by	by	IN
cord-004222-z4butywi	97	21	a	a	DT
cord-004222-z4butywi	97	22	maximum	maximum	JJ
cord-004222-z4butywi	97	23	two	two	CD
cord-004222-z4butywi	97	24	orders	order	NNS
cord-004222-z4butywi	97	25	of	of	IN
cord-004222-z4butywi	97	26	magnitude	magnitude	NN
cord-004222-z4butywi	97	27	.	.	.
cord-004222-z4butywi	98	1	This	this	DT
cord-004222-z4butywi	98	2	is	be	VBZ
cord-004222-z4butywi	98	3	surprising	surprising	JJ
cord-004222-z4butywi	98	4	given	give	VBN
cord-004222-z4butywi	98	5	that	that	IN
cord-004222-z4butywi	98	6	the	the	DT
cord-004222-z4butywi	98	7	OmniRat	OmniRat	NNP
cord-004222-z4butywi	98	8	is	be	VBZ
cord-004222-z4butywi	98	9	more	more	RBR
cord-004222-z4butywi	98	10	restricted	restricted	JJ
cord-004222-z4butywi	98	11	in	in	IN
cord-004222-z4butywi	98	12	CDRH3	cdrh3	NN
cord-004222-z4butywi	98	13	length	length	NN
cord-004222-z4butywi	98	14	.	.	.
cord-004222-z4butywi	99	1	For	for	IN
cord-004222-z4butywi	99	2	each	each	DT
cord-004222-z4butywi	99	3	combination	combination	NN
cord-004222-z4butywi	99	4	of	of	IN
cord-004222-z4butywi	99	5	two	two	CD
cord-004222-z4butywi	99	6	or	or	CC
cord-004222-z4butywi	99	7	more	more	JJR
cord-004222-z4butywi	99	8	animals	animal	NNS
cord-004222-z4butywi	99	9	,	,	,
cord-004222-z4butywi	99	10	we	-PRON-	PRP
cord-004222-z4butywi	99	11	computed	compute	VBD
cord-004222-z4butywi	99	12	the	the	DT
cord-004222-z4butywi	99	13	frequency	frequency	NN
cord-004222-z4butywi	99	14	of	of	IN
cord-004222-z4butywi	99	15	shared	share	VBN
cord-004222-z4butywi	99	16	unique	unique	JJ
cord-004222-z4butywi	99	17	heavy	heavy	JJ
cord-004222-z4butywi	99	18	chain	chain	NN
cord-004222-z4butywi	99	19	clonotypes	clonotype	NNS
cord-004222-z4butywi	99	20	(	(	-LRB-
cord-004222-z4butywi	99	21	Fig	Fig	NNP
cord-004222-z4butywi	99	22	.	.	.
cord-004222-z4butywi	99	23	4a	4a	CD
cord-004222-z4butywi	99	24	)	)	-RRB-
cord-004222-z4butywi	99	25	.	.	.
cord-004222-z4butywi	100	1	There	there	EX
cord-004222-z4butywi	100	2	was	be	VBD
cord-004222-z4butywi	100	3	on	on	IN
cord-004222-z4butywi	100	4	average	average	JJ
cord-004222-z4butywi	100	5	9.32	9.32	CD
cord-004222-z4butywi	100	6	%	%	NN
cord-004222-z4butywi	100	7	of	of	IN
cord-004222-z4butywi	100	8	clonotypes	clonotype	NNS
cord-004222-z4butywi	100	9	shared	share	VBN
cord-004222-z4butywi	100	10	between	between	IN
cord-004222-z4butywi	100	11	each	each	DT
cord-004222-z4butywi	100	12	combination	combination	NN
cord-004222-z4butywi	100	13	of	of	IN
cord-004222-z4butywi	100	14	two	two	CD
cord-004222-z4butywi	100	15	OmniRats	OmniRats	NNPS
cord-004222-z4butywi	100	16	.	.	.
cord-004222-z4butywi	101	1	Surprisingly	surprisingly	RB
cord-004222-z4butywi	101	2	,	,	,
cord-004222-z4butywi	101	3	we	-PRON-	PRP
cord-004222-z4butywi	101	4	found	find	VBD
cord-004222-z4butywi	101	5	that	that	IN
cord-004222-z4butywi	101	6	4.90	4.90	CD
cord-004222-z4butywi	101	7	%	%	NN
cord-004222-z4butywi	101	8	of	of	IN
cord-004222-z4butywi	101	9	clonotypes	clonotype	NNS
cord-004222-z4butywi	101	10	were	be	VBD
cord-004222-z4butywi	101	11	shared	share	VBN
cord-004222-z4butywi	101	12	between	between	IN
cord-004222-z4butywi	101	13	all	all	DT
cord-004222-z4butywi	101	14	three	three	CD
cord-004222-z4butywi	101	15	of	of	IN
cord-004222-z4butywi	101	16	the	the	DT
cord-004222-z4butywi	101	17	animals	animal	NNS
cord-004222-z4butywi	101	18	.	.	.
cord-004222-z4butywi	102	1	Next	next	RB
cord-004222-z4butywi	102	2	,	,	,
cord-004222-z4butywi	102	3	we	-PRON-	PRP
cord-004222-z4butywi	102	4	pooled	pool	VBD
cord-004222-z4butywi	102	5	unique	unique	JJ
cord-004222-z4butywi	102	6	heavy	heavy	JJ
cord-004222-z4butywi	102	7	chain	chain	NN
cord-004222-z4butywi	102	8	clonotypes	clonotype	NNS
cord-004222-z4butywi	102	9	from	from	IN
cord-004222-z4butywi	102	10	all	all	DT
cord-004222-z4butywi	102	11	ten	ten	CD
cord-004222-z4butywi	102	12	human	human	JJ
cord-004222-z4butywi	102	13	subjects	subject	NNS
cord-004222-z4butywi	102	14	and	and	CC
cord-004222-z4butywi	102	15	measured	measure	VBD
cord-004222-z4butywi	102	16	the	the	DT
cord-004222-z4butywi	102	17	percentage	percentage	NN
cord-004222-z4butywi	102	18	of	of	IN
cord-004222-z4butywi	102	19	clonotypes	clonotype	NNS
cord-004222-z4butywi	102	20	in	in	IN
cord-004222-z4butywi	102	21	each	each	DT
cord-004222-z4butywi	102	22	animal	animal	NN
cord-004222-z4butywi	102	23	that	that	WDT
cord-004222-z4butywi	102	24	could	could	MD
cord-004222-z4butywi	102	25	be	be	VB
cord-004222-z4butywi	102	26	found	find	VBN
cord-004222-z4butywi	102	27	in	in	IN
cord-004222-z4butywi	102	28	the	the	DT
cord-004222-z4butywi	102	29	total	total	JJ
cord-004222-z4butywi	102	30	human	human	JJ
cord-004222-z4butywi	102	31	pool	pool	NN
cord-004222-z4butywi	102	32	(	(	-LRB-
cord-004222-z4butywi	102	33	Fig	Fig	NNP
cord-004222-z4butywi	102	34	.	.	.
cord-004222-z4butywi	102	35	4b	4b	CD
cord-004222-z4butywi	102	36	)	)	-RRB-
cord-004222-z4butywi	102	37	.	.	.
cord-004222-z4butywi	103	1	We	-PRON-	PRP
cord-004222-z4butywi	103	2	found	find	VBD
cord-004222-z4butywi	103	3	that	that	IN
cord-004222-z4butywi	103	4	(	(	-LRB-
cord-004222-z4butywi	103	5	11.9	11.9	CD
cord-004222-z4butywi	103	6	-	-	SYM
cord-004222-z4butywi	103	7	13.7	13.7	CD
cord-004222-z4butywi	103	8	%	%	NN
cord-004222-z4butywi	103	9	)	)	-RRB-
cord-004222-z4butywi	103	10	of	of	IN
cord-004222-z4butywi	103	11	each	each	DT
cord-004222-z4butywi	103	12	OmniRat	omnirat	NN
cord-004222-z4butywi	103	13	clonotype	clonotype	NN
cord-004222-z4butywi	103	14	repertoire	repertoire	NN
cord-004222-z4butywi	103	15	and	and	CC
cord-004222-z4butywi	103	16	13.8	13.8	CD
cord-004222-z4butywi	103	17	%	%	NN
cord-004222-z4butywi	103	18	of	of	IN
cord-004222-z4butywi	103	19	clonotypes	clonotype	NNS
cord-004222-z4butywi	103	20	combined	combine	VBN
cord-004222-z4butywi	103	21	from	from	IN
cord-004222-z4butywi	103	22	all	all	DT
cord-004222-z4butywi	103	23	animals	animal	NNS
cord-004222-z4butywi	103	24	could	could	MD
cord-004222-z4butywi	103	25	be	be	VB
cord-004222-z4butywi	103	26	found	find	VBN
cord-004222-z4butywi	103	27	in	in	IN
cord-004222-z4butywi	103	28	the	the	DT
cord-004222-z4butywi	103	29	total	total	JJ
cord-004222-z4butywi	103	30	human	human	JJ
cord-004222-z4butywi	103	31	clonotype	clonotype	NN
cord-004222-z4butywi	103	32	pool	pool	NN
cord-004222-z4butywi	103	33	.	.	.
cord-004222-z4butywi	104	1	Shared	share	VBN
cord-004222-z4butywi	104	2	clonotypes	clonotype	NNS
cord-004222-z4butywi	104	3	have	have	VBP
cord-004222-z4butywi	104	4	shorter	short	JJR
cord-004222-z4butywi	104	5	CDRH3	cdrh3	NN
cord-004222-z4butywi	104	6	lengths	length	NNS
cord-004222-z4butywi	104	7	than	than	IN
cord-004222-z4butywi	104	8	unshared	unshared	JJ
cord-004222-z4butywi	104	9	clonotypes	clonotype	NNS
cord-004222-z4butywi	104	10	on	on	IN
cord-004222-z4butywi	104	11	average	average	JJ
cord-004222-z4butywi	104	12	(	(	-LRB-
cord-004222-z4butywi	104	13	Fig	Fig	NNP
cord-004222-z4butywi	104	14	.	.	NNP
cord-004222-z4butywi	104	15	4c	4c	LS
cord-004222-z4butywi	104	16	)	)	-RRB-
cord-004222-z4butywi	104	17	which	which	WDT
cord-004222-z4butywi	104	18	is	be	VBZ
cord-004222-z4butywi	104	19	expected	expect	VBN
cord-004222-z4butywi	104	20	given	give	VBN
cord-004222-z4butywi	104	21	that	that	DT
cord-004222-z4butywi	104	22	sequence	sequence	NN
cord-004222-z4butywi	104	23	diversity	diversity	NN
cord-004222-z4butywi	104	24	is	be	VBZ
cord-004222-z4butywi	104	25	expected	expect	VBN
cord-004222-z4butywi	104	26	to	to	TO
cord-004222-z4butywi	104	27	increase	increase	VB
cord-004222-z4butywi	104	28	as	as	IN
cord-004222-z4butywi	104	29	the	the	DT
cord-004222-z4butywi	104	30	number	number	NN
cord-004222-z4butywi	104	31	of	of	IN
cord-004222-z4butywi	104	32	amino	amino	JJ
cord-004222-z4butywi	104	33	acids	acid	NNS
cord-004222-z4butywi	104	34	increases	increase	VBZ
cord-004222-z4butywi	104	35	giving	give	VBG
cord-004222-z4butywi	104	36	less	less	JJR
cord-004222-z4butywi	104	37	of	of	IN
cord-004222-z4butywi	104	38	a	a	DT
cord-004222-z4butywi	104	39	chance	chance	NN
cord-004222-z4butywi	104	40	for	for	IN
cord-004222-z4butywi	104	41	sharing	sharing	NN
cord-004222-z4butywi	104	42	.	.	.
cord-004222-z4butywi	105	1	VH	VH	NNP
cord-004222-z4butywi	105	2	gene	gene	NN
cord-004222-z4butywi	105	3	family	family	NN
cord-004222-z4butywi	105	4	usage	usage	NN
cord-004222-z4butywi	105	5	between	between	IN
cord-004222-z4butywi	105	6	shared	shared	JJ
cord-004222-z4butywi	105	7	and	and	CC
cord-004222-z4butywi	105	8	unshared	unshared	JJ
cord-004222-z4butywi	105	9	clonotypes	clonotype	NNS
cord-004222-z4butywi	105	10	indicates	indicate	VBZ
cord-004222-z4butywi	105	11	no	no	DT
cord-004222-z4butywi	105	12	major	major	JJ
cord-004222-z4butywi	105	13	differences	difference	NNS
cord-004222-z4butywi	105	14	(	(	-LRB-
cord-004222-z4butywi	105	15	Fig	Fig	NNP
cord-004222-z4butywi	105	16	.	.	.
cord-004222-z4butywi	105	17	4d	4d	CD
cord-004222-z4butywi	105	18	)	)	-RRB-
cord-004222-z4butywi	105	19	.	.	.
cord-004222-z4butywi	106	1	Sequence	sequence	NN
cord-004222-z4butywi	106	2	logos	logo	NNS
cord-004222-z4butywi	106	3	for	for	IN
cord-004222-z4butywi	106	4	8	8	CD
cord-004222-z4butywi	106	5	amino	amino	NN
cord-004222-z4butywi	106	6	acid	acid	NN
cord-004222-z4butywi	106	7	long	long	RB
cord-004222-z4butywi	107	1	(	(	-LRB-
cord-004222-z4butywi	107	2	Fig	Fig	NNP
cord-004222-z4butywi	107	3	.	.	.
cord-004222-z4butywi	107	4	4e	4e	LS
cord-004222-z4butywi	107	5	)	)	-RRB-
cord-004222-z4butywi	107	6	and	and	CC
cord-004222-z4butywi	108	1	13	13	CD
cord-004222-z4butywi	108	2	amino	amino	NN
cord-004222-z4butywi	108	3	acid	acid	NN
cord-004222-z4butywi	108	4	long	long	RB
cord-004222-z4butywi	109	1	(	(	-LRB-
cord-004222-z4butywi	109	2	Fig	Fig	NNP
cord-004222-z4butywi	109	3	.	.	.
cord-004222-z4butywi	109	4	4e	4e	LS
cord-004222-z4butywi	109	5	)	)	-RRB-
cord-004222-z4butywi	110	1	CDHR3s	cdhr3s	JJ
cord-004222-z4butywi	110	2	from	from	IN
cord-004222-z4butywi	110	3	both	both	CC
cord-004222-z4butywi	110	4	shared	share	VBN
cord-004222-z4butywi	110	5	and	and	CC
cord-004222-z4butywi	110	6	unshared	unshared	JJ
cord-004222-z4butywi	110	7	fractions	fraction	NNS
cord-004222-z4butywi	110	8	were	be	VBD
cord-004222-z4butywi	110	9	made	make	VBN
cord-004222-z4butywi	110	10	and	and	CC
cord-004222-z4butywi	110	11	indicate	indicate	VB
cord-004222-z4butywi	110	12	broad	broad	JJ
cord-004222-z4butywi	110	13	similarity	similarity	NN
cord-004222-z4butywi	110	14	between	between	IN
cord-004222-z4butywi	110	15	the	the	DT
cord-004222-z4butywi	110	16	two	two	CD
cord-004222-z4butywi	110	17	fractions	fraction	NNS
cord-004222-z4butywi	110	18	.	.	.
cord-004222-z4butywi	111	1	We	-PRON-	PRP
cord-004222-z4butywi	111	2	set	set	VBD
cord-004222-z4butywi	111	3	out	out	RP
cord-004222-z4butywi	111	4	to	to	TO
cord-004222-z4butywi	111	5	determine	determine	VB
cord-004222-z4butywi	111	6	commonalities	commonality	NNS
cord-004222-z4butywi	111	7	and	and	CC
cord-004222-z4butywi	111	8	differences	difference	NNS
cord-004222-z4butywi	111	9	between	between	IN
cord-004222-z4butywi	111	10	OmniRat	omnirat	NN
cord-004222-z4butywi	111	11	and	and	CC
cord-004222-z4butywi	111	12	human	human	JJ
cord-004222-z4butywi	111	13	antibody	antibody	NN
cord-004222-z4butywi	111	14	repertoires	repertoire	NNS
cord-004222-z4butywi	111	15	to	to	TO
cord-004222-z4butywi	111	16	be	be	VB
cord-004222-z4butywi	111	17	used	use	VBN
cord-004222-z4butywi	111	18	as	as	IN
cord-004222-z4butywi	111	19	a	a	DT
cord-004222-z4butywi	111	20	reference	reference	NN
cord-004222-z4butywi	111	21	for	for	IN
cord-004222-z4butywi	111	22	vaccine	vaccine	NN
cord-004222-z4butywi	111	23	studies	study	NNS
cord-004222-z4butywi	111	24	.	.	.
cord-004222-z4butywi	112	1	Our	-PRON-	PRP$
cord-004222-z4butywi	112	2	results	result	NNS
cord-004222-z4butywi	112	3	show	show	VBP
cord-004222-z4butywi	112	4	that	that	IN
cord-004222-z4butywi	112	5	there	there	EX
cord-004222-z4butywi	112	6	exists	exist	VBZ
cord-004222-z4butywi	112	7	substantial	substantial	JJ
cord-004222-z4butywi	112	8	variation	variation	NN
cord-004222-z4butywi	112	9	in	in	IN
cord-004222-z4butywi	112	10	gene	gene	NN
cord-004222-z4butywi	112	11	usage	usage	NN
cord-004222-z4butywi	112	12	frequencies	frequency	NNS
cord-004222-z4butywi	112	13	and	and	CC
cord-004222-z4butywi	112	14	elements	element	NNS
cord-004222-z4butywi	112	15	of	of	IN
cord-004222-z4butywi	112	16	recombination	recombination	NN
cord-004222-z4butywi	112	17	,	,	,
cord-004222-z4butywi	112	18	indicating	indicate	VBG
cord-004222-z4butywi	112	19	specific	specific	JJ
cord-004222-z4butywi	112	20	limitations	limitation	NNS
cord-004222-z4butywi	112	21	of	of	IN
cord-004222-z4butywi	112	22	this	this	DT
cord-004222-z4butywi	112	23	animal	animal	NN
cord-004222-z4butywi	112	24	model	model	NN
cord-004222-z4butywi	112	25	for	for	IN
cord-004222-z4butywi	112	26	predicting	predict	VBG
cord-004222-z4butywi	112	27	the	the	DT
cord-004222-z4butywi	112	28	human	human	JJ
cord-004222-z4butywi	112	29	immune	immune	JJ
cord-004222-z4butywi	112	30	response	response	NN
cord-004222-z4butywi	112	31	.	.	.
cord-004222-z4butywi	113	1	We	-PRON-	PRP
cord-004222-z4butywi	113	2	found	find	VBD
cord-004222-z4butywi	113	3	that	that	IN
cord-004222-z4butywi	113	4	by	by	IN
cord-004222-z4butywi	113	5	performing	perform	VBG
cord-004222-z4butywi	113	6	hierarchical	hierarchical	JJ
cord-004222-z4butywi	113	7	clustering	clustering	NN
cord-004222-z4butywi	113	8	on	on	IN
cord-004222-z4butywi	113	9	gene	gene	NN
cord-004222-z4butywi	113	10	segment	segment	NN
cord-004222-z4butywi	113	11	usage	usage	NN
cord-004222-z4butywi	113	12	,	,	,
cord-004222-z4butywi	113	13	repertoires	repertoire	NNS
cord-004222-z4butywi	113	14	clustered	cluster	VBN
cord-004222-z4butywi	113	15	together	together	RB
cord-004222-z4butywi	113	16	by	by	IN
cord-004222-z4butywi	113	17	both	both	DT
cord-004222-z4butywi	113	18	species	specie	NNS
cord-004222-z4butywi	113	19	and	and	CC
cord-004222-z4butywi	113	20	tissue	tissue	NN
cord-004222-z4butywi	113	21	.	.	.
cord-004222-z4butywi	114	1	Differences	difference	NNS
cord-004222-z4butywi	114	2	in	in	IN
cord-004222-z4butywi	114	3	gene	gene	NN
cord-004222-z4butywi	114	4	segment	segment	NN
cord-004222-z4butywi	114	5	usage	usage	NN
cord-004222-z4butywi	114	6	between	between	IN
cord-004222-z4butywi	114	7	transgenic	transgenic	JJ
cord-004222-z4butywi	114	8	animal	animal	NN
cord-004222-z4butywi	114	9	models	model	NNS
cord-004222-z4butywi	114	10	and	and	CC
cord-004222-z4butywi	114	11	humans	human	NNS
cord-004222-z4butywi	114	12	,	,	,
cord-004222-z4butywi	114	13	as	as	RB
cord-004222-z4butywi	114	14	well	well	RB
cord-004222-z4butywi	114	15	as	as	IN
cord-004222-z4butywi	114	16	between	between	IN
cord-004222-z4butywi	114	17	tissues	tissue	NNS
cord-004222-z4butywi	114	18	are	be	VBP
cord-004222-z4butywi	114	19	expected	expect	VBN
cord-004222-z4butywi	114	20	.	.	.
cord-004222-z4butywi	115	1	For	for	IN
cord-004222-z4butywi	115	2	example	example	NN
cord-004222-z4butywi	115	3	,	,	,
cord-004222-z4butywi	115	4	multiple	multiple	JJ
cord-004222-z4butywi	115	5	human	human	JJ
cord-004222-z4butywi	115	6	Ig	ig	NN
cord-004222-z4butywi	115	7	loci	locus	NNS
cord-004222-z4butywi	115	8	transgenic	transgenic	JJ
cord-004222-z4butywi	115	9	rodents	rodent	NNS
cord-004222-z4butywi	115	10	are	be	VBP
cord-004222-z4butywi	115	11	reported	report	VBN
cord-004222-z4butywi	115	12	to	to	TO
cord-004222-z4butywi	115	13	have	have	VB
cord-004222-z4butywi	115	14	gene	gene	NN
cord-004222-z4butywi	115	15	usage	usage	NN
cord-004222-z4butywi	115	16	profiles	profile	NNS
cord-004222-z4butywi	115	17	that	that	WDT
cord-004222-z4butywi	115	18	slightly	slightly	RB
cord-004222-z4butywi	115	19	vary	vary	VBP
cord-004222-z4butywi	115	20	from	from	IN
cord-004222-z4butywi	115	21	that	that	DT
cord-004222-z4butywi	115	22	of	of	IN
cord-004222-z4butywi	115	23	humans	human	NNS
cord-004222-z4butywi	115	24	25	25	CD
cord-004222-z4butywi	115	25	,	,	,
cord-004222-z4butywi	115	26	26	26	CD
cord-004222-z4butywi	115	27	.	.	.
cord-004222-z4butywi	116	1	Furthermore	furthermore	RB
cord-004222-z4butywi	116	2	,	,	,
cord-004222-z4butywi	116	3	antibody	antibody	NN
cord-004222-z4butywi	116	4	repertoires	repertoire	NNS
cord-004222-z4butywi	116	5	from	from	IN
cord-004222-z4butywi	116	6	separate	separate	JJ
cord-004222-z4butywi	116	7	human	human	JJ
cord-004222-z4butywi	116	8	tissues	tissue	NNS
cord-004222-z4butywi	116	9	are	be	VBP
cord-004222-z4butywi	116	10	known	know	VBN
cord-004222-z4butywi	116	11	to	to	TO
cord-004222-z4butywi	116	12	deviate	deviate	VB
cord-004222-z4butywi	116	13	strongly	strongly	RB
cord-004222-z4butywi	116	14	enough	enough	RB
cord-004222-z4butywi	116	15	to	to	TO
cord-004222-z4butywi	116	16	be	be	VB
cord-004222-z4butywi	116	17	clustered	cluster	VBN
cord-004222-z4butywi	116	18	by	by	IN
cord-004222-z4butywi	116	19	hierarchical	hierarchical	JJ
cord-004222-z4butywi	116	20	clustering	clustering	NN
cord-004222-z4butywi	116	21	27	27	CD
cord-004222-z4butywi	116	22	.	.	.
cord-004222-z4butywi	117	1	In	in	IN
cord-004222-z4butywi	117	2	our	-PRON-	PRP$
cord-004222-z4butywi	117	3	case	case	NN
cord-004222-z4butywi	117	4	,	,	,
cord-004222-z4butywi	117	5	the	the	DT
cord-004222-z4butywi	117	6	lymph	lymph	NN
cord-004222-z4butywi	117	7	node	node	NN
cord-004222-z4butywi	117	8	repertoire	repertoire	NN
cord-004222-z4butywi	117	9	from	from	IN
cord-004222-z4butywi	117	10	the	the	DT
cord-004222-z4butywi	117	11	OmniRat	OmniRat	NNP
cord-004222-z4butywi	117	12	was	be	VBD
cord-004222-z4butywi	117	13	most	most	RBS
cord-004222-z4butywi	117	14	likely	likely	RB
cord-004222-z4butywi	117	15	able	able	JJ
cord-004222-z4butywi	117	16	to	to	TO
cord-004222-z4butywi	117	17	be	be	VB
cord-004222-z4butywi	117	18	distinguished	distinguish	VBN
cord-004222-z4butywi	117	19	from	from	IN
cord-004222-z4butywi	117	20	that	that	DT
cord-004222-z4butywi	117	21	of	of	IN
cord-004222-z4butywi	117	22	the	the	DT
cord-004222-z4butywi	117	23	spleen	spleen	NN
cord-004222-z4butywi	117	24	due	due	IN
cord-004222-z4butywi	117	25	to	to	IN
cord-004222-z4butywi	117	26	the	the	DT
cord-004222-z4butywi	117	27	increased	increase	VBN
cord-004222-z4butywi	117	28	presence	presence	NN
cord-004222-z4butywi	117	29	of	of	IN
cord-004222-z4butywi	117	30	antigen	antigen	NN
cord-004222-z4butywi	117	31	-	-	HYPH
cord-004222-z4butywi	117	32	experienced	experience	VBN
cord-004222-z4butywi	117	33	B	B	NNP
cord-004222-z4butywi	117	34	cells	cell	NNS
cord-004222-z4butywi	117	35	in	in	IN
cord-004222-z4butywi	117	36	the	the	DT
cord-004222-z4butywi	117	37	latter	latter	JJ
cord-004222-z4butywi	117	38	as	as	IN
cord-004222-z4butywi	117	39	shown	show	VBN
cord-004222-z4butywi	117	40	by	by	IN
cord-004222-z4butywi	117	41	somatic	somatic	JJ
cord-004222-z4butywi	117	42	hypermutation	hypermutation	NN
cord-004222-z4butywi	117	43	and	and	CC
cord-004222-z4butywi	117	44	class	class	NN
cord-004222-z4butywi	117	45	-	-	HYPH
cord-004222-z4butywi	117	46	switched	switch	VBN
cord-004222-z4butywi	117	47	transcript	transcript	NN
cord-004222-z4butywi	117	48	frequencies	frequency	NNS
cord-004222-z4butywi	117	49	.	.	.
cord-004222-z4butywi	118	1	This	this	DT
cord-004222-z4butywi	118	2	indicates	indicate	VBZ
cord-004222-z4butywi	118	3	that	that	IN
cord-004222-z4butywi	118	4	tissue	tissue	NN
cord-004222-z4butywi	118	5	selection	selection	NN
cord-004222-z4butywi	118	6	will	will	MD
cord-004222-z4butywi	118	7	affect	affect	VB
cord-004222-z4butywi	118	8	the	the	DT
cord-004222-z4butywi	118	9	outcome	outcome	NN
cord-004222-z4butywi	118	10	of	of	IN
cord-004222-z4butywi	118	11	an	an	DT
cord-004222-z4butywi	118	12	antibody	antibody	NN
cord-004222-z4butywi	118	13	discovery	discovery	NN
cord-004222-z4butywi	118	14	campaign	campaign	NN
cord-004222-z4butywi	118	15	and	and	CC
cord-004222-z4butywi	118	16	reinforces	reinforce	VBZ
cord-004222-z4butywi	118	17	evidence	evidence	NN
cord-004222-z4butywi	118	18	for	for	IN
cord-004222-z4butywi	118	19	normal	normal	JJ
cord-004222-z4butywi	118	20	B	b	NN
cord-004222-z4butywi	118	21	cell	cell	NN
cord-004222-z4butywi	118	22	development	development	NN
cord-004222-z4butywi	118	23	by	by	IN
cord-004222-z4butywi	118	24	suggesting	suggest	VBG
cord-004222-z4butywi	118	25	the	the	DT
cord-004222-z4butywi	118	26	existence	existence	NN
cord-004222-z4butywi	118	27	of	of	IN
cord-004222-z4butywi	118	28	affinity	affinity	NN
cord-004222-z4butywi	118	29	maturation	maturation	NN
cord-004222-z4butywi	118	30	.	.	.
cord-004222-z4butywi	119	1	Investigation	investigation	NN
cord-004222-z4butywi	119	2	into	into	IN
cord-004222-z4butywi	119	3	CDR3	CDR3	NNP
cord-004222-z4butywi	119	4	length	length	NN
cord-004222-z4butywi	119	5	distributions	distribution	NNS
cord-004222-z4butywi	119	6	revealed	reveal	VBD
cord-004222-z4butywi	119	7	that	that	IN
cord-004222-z4butywi	119	8	the	the	DT
cord-004222-z4butywi	119	9	OmniRat	OmniRat	NNP
cord-004222-z4butywi	119	10	prefers	prefer	VBZ
cord-004222-z4butywi	119	11	shorter	short	JJR
cord-004222-z4butywi	119	12	CDRH3s	cdrh3s	NN
cord-004222-z4butywi	119	13	as	as	IN
cord-004222-z4butywi	119	14	compared	compare	VBN
cord-004222-z4butywi	119	15	to	to	IN
cord-004222-z4butywi	119	16	humans	human	NNS
cord-004222-z4butywi	119	17	.	.	.
cord-004222-z4butywi	120	1	Interestingly	interestingly	RB
cord-004222-z4butywi	120	2	,	,	,
cord-004222-z4butywi	120	3	the	the	DT
cord-004222-z4butywi	120	4	mechanisms	mechanism	NNS
cord-004222-z4butywi	120	5	of	of	IN
cord-004222-z4butywi	120	6	this	this	DT
cord-004222-z4butywi	120	7	preference	preference	NN
cord-004222-z4butywi	120	8	are	be	VBP
cord-004222-z4butywi	120	9	due	due	JJ
cord-004222-z4butywi	120	10	to	to	IN
cord-004222-z4butywi	120	11	decreased	decrease	VBN
cord-004222-z4butywi	120	12	N	n	CD
cord-004222-z4butywi	120	13	additions	addition	NNS
cord-004222-z4butywi	120	14	,	,	,
cord-004222-z4butywi	120	15	and	and	CC
cord-004222-z4butywi	120	16	a	a	DT
cord-004222-z4butywi	120	17	tendency	tendency	NN
cord-004222-z4butywi	120	18	to	to	TO
cord-004222-z4butywi	120	19	incorporate	incorporate	VB
cord-004222-z4butywi	120	20	shorter	short	JJR
cord-004222-z4butywi	120	21	DH	dh	NN
cord-004222-z4butywi	120	22	gene	gene	NN
cord-004222-z4butywi	120	23	segments	segment	NNS
cord-004222-z4butywi	120	24	.	.	.
cord-004222-z4butywi	121	1	This	this	DT
cord-004222-z4butywi	121	2	result	result	NN
cord-004222-z4butywi	121	3	has	have	VBZ
cord-004222-z4butywi	121	4	also	also	RB
cord-004222-z4butywi	121	5	been	be	VBN
cord-004222-z4butywi	121	6	seen	see	VBN
cord-004222-z4butywi	121	7	in	in	IN
cord-004222-z4butywi	121	8	multiple	multiple	JJ
cord-004222-z4butywi	121	9	other	other	JJ
cord-004222-z4butywi	121	10	transgenic	transgenic	JJ
cord-004222-z4butywi	121	11	and	and	CC
cord-004222-z4butywi	121	12	wild	wild	JJ
cord-004222-z4butywi	121	13	-	-	HYPH
cord-004222-z4butywi	121	14	type	type	NN
cord-004222-z4butywi	121	15	rodents	rodent	NNS
cord-004222-z4butywi	121	16	25	25	CD
cord-004222-z4butywi	121	17	,	,	,
cord-004222-z4butywi	121	18	26	26	CD
cord-004222-z4butywi	121	19	,	,	,
cord-004222-z4butywi	121	20	28	28	CD
cord-004222-z4butywi	121	21	,	,	,
cord-004222-z4butywi	121	22	29	29	CD
cord-004222-z4butywi	121	23	.	.	.
cord-004222-z4butywi	122	1	The	the	DT
cord-004222-z4butywi	122	2	specific	specific	JJ
cord-004222-z4butywi	122	3	reasons	reason	NNS
cord-004222-z4butywi	122	4	remain	remain	VBP
cord-004222-z4butywi	122	5	unclear	unclear	JJ
cord-004222-z4butywi	122	6	,	,	,
cord-004222-z4butywi	122	7	although	although	IN
cord-004222-z4butywi	122	8	the	the	DT
cord-004222-z4butywi	122	9	observation	observation	NN
cord-004222-z4butywi	122	10	that	that	IN
cord-004222-z4butywi	122	11	wild	wild	JJ
cord-004222-z4butywi	122	12	-	-	HYPH
cord-004222-z4butywi	122	13	type	type	NN
cord-004222-z4butywi	122	14	rat	rat	NN
cord-004222-z4butywi	122	15	germline	germline	NN
cord-004222-z4butywi	122	16	D	d	NN
cord-004222-z4butywi	122	17	gene	gene	NN
cord-004222-z4butywi	122	18	segment	segment	NN
cord-004222-z4butywi	122	19	lengths	length	NNS
cord-004222-z4butywi	122	20	are	be	VBP
cord-004222-z4butywi	122	21	shorter	short	JJR
cord-004222-z4butywi	122	22	suggests	suggest	VBZ
cord-004222-z4butywi	122	23	intrinsic	intrinsic	JJ
cord-004222-z4butywi	122	24	species	species	NN
cord-004222-z4butywi	122	25	-	-	HYPH
cord-004222-z4butywi	122	26	specific	specific	JJ
cord-004222-z4butywi	122	27	mechanisms	mechanism	NNS
cord-004222-z4butywi	122	28	of	of	IN
cord-004222-z4butywi	122	29	selection	selection	NN
cord-004222-z4butywi	122	30	as	as	RB
cord-004222-z4butywi	122	31	well	well	RB
cord-004222-z4butywi	122	32	as	as	IN
cord-004222-z4butywi	122	33	differences	difference	NNS
cord-004222-z4butywi	122	34	in	in	IN
cord-004222-z4butywi	122	35	TdT	tdt	NN
cord-004222-z4butywi	122	36	expression	expression	NN
cord-004222-z4butywi	122	37	during	during	IN
cord-004222-z4butywi	122	38	bone	bone	NN
cord-004222-z4butywi	122	39	marrow	marrow	NN
cord-004222-z4butywi	122	40	B	b	NN
cord-004222-z4butywi	122	41	cell	cell	NN
cord-004222-z4butywi	122	42	development	development	NN
cord-004222-z4butywi	122	43	.	.	.
cord-004222-z4butywi	123	1	We	-PRON-	PRP
cord-004222-z4butywi	123	2	further	further	RB
cord-004222-z4butywi	123	3	speculate	speculate	VBP
cord-004222-z4butywi	123	4	that	that	IN
cord-004222-z4butywi	123	5	another	another	DT
cord-004222-z4butywi	123	6	possible	possible	JJ
cord-004222-z4butywi	123	7	reason	reason	NN
cord-004222-z4butywi	123	8	for	for	IN
cord-004222-z4butywi	123	9	intra	intra	JJ
cord-004222-z4butywi	123	10	-	-	JJ
cord-004222-z4butywi	123	11	species	species	JJ
cord-004222-z4butywi	123	12	variation	variation	NN
cord-004222-z4butywi	123	13	can	can	MD
cord-004222-z4butywi	123	14	be	be	VB
cord-004222-z4butywi	123	15	attributed	attribute	VBN
cord-004222-z4butywi	123	16	to	to	IN
cord-004222-z4butywi	123	17	distinct	distinct	JJ
cord-004222-z4butywi	123	18	prior	prior	JJ
cord-004222-z4butywi	123	19	antigen	antigen	NN
cord-004222-z4butywi	123	20	exposure	exposure	NN
cord-004222-z4butywi	123	21	and	and	CC
cord-004222-z4butywi	123	22	divergent	divergent	JJ
cord-004222-z4butywi	123	23	gut	gut	NN
cord-004222-z4butywi	123	24	microbiomes	microbiome	NNS
cord-004222-z4butywi	123	25	30	30	CD
cord-004222-z4butywi	123	26	,	,	,
cord-004222-z4butywi	123	27	31	31	CD
cord-004222-z4butywi	123	28	.	.	.
cord-004222-z4butywi	124	1	The	the	DT
cord-004222-z4butywi	124	2	diversity	diversity	NN
cord-004222-z4butywi	124	3	of	of	IN
cord-004222-z4butywi	124	4	the	the	DT
cord-004222-z4butywi	124	5	OmniRat	OmniRat	NNP
cord-004222-z4butywi	124	6	heavy	heavy	JJ
cord-004222-z4butywi	124	7	chain	chain	NN
cord-004222-z4butywi	124	8	repertoire	repertoire	NN
cord-004222-z4butywi	124	9	was	be	VBD
cord-004222-z4butywi	124	10	shown	show	VBN
cord-004222-z4butywi	124	11	to	to	TO
cord-004222-z4butywi	124	12	be	be	VB
cord-004222-z4butywi	124	13	slightly	slightly	RB
cord-004222-z4butywi	124	14	lower	low	JJR
cord-004222-z4butywi	124	15	than	than	IN
cord-004222-z4butywi	124	16	that	that	DT
cord-004222-z4butywi	124	17	in	in	IN
cord-004222-z4butywi	124	18	humans	human	NNS
cord-004222-z4butywi	124	19	.	.	.
cord-004222-z4butywi	125	1	Our	-PRON-	PRP$
cord-004222-z4butywi	125	2	results	result	NNS
cord-004222-z4butywi	125	3	indicate	indicate	VBP
cord-004222-z4butywi	125	4	biased	biased	JJ
cord-004222-z4butywi	125	5	gene	gene	NN
cord-004222-z4butywi	125	6	usage	usage	NN
cord-004222-z4butywi	125	7	and	and	CC
cord-004222-z4butywi	125	8	decreased	decrease	VBD
cord-004222-z4butywi	125	9	junctional	junctional	JJ
cord-004222-z4butywi	125	10	diversity	diversity	NN
cord-004222-z4butywi	125	11	are	be	VBP
cord-004222-z4butywi	125	12	the	the	DT
cord-004222-z4butywi	125	13	primary	primary	JJ
cord-004222-z4butywi	125	14	reasons	reason	NNS
cord-004222-z4butywi	125	15	for	for	IN
cord-004222-z4butywi	125	16	the	the	DT
cord-004222-z4butywi	125	17	resulting	result	VBG
cord-004222-z4butywi	125	18	repertoire	repertoire	NN
cord-004222-z4butywi	125	19	diversity	diversity	NN
cord-004222-z4butywi	125	20	estimate	estimate	NN
cord-004222-z4butywi	125	21	comparisons	comparison	NNS
cord-004222-z4butywi	125	22	.	.	.
cord-004222-z4butywi	126	1	We	-PRON-	PRP
cord-004222-z4butywi	126	2	also	also	RB
cord-004222-z4butywi	126	3	showed	show	VBD
cord-004222-z4butywi	126	4	that	that	IN
cord-004222-z4butywi	126	5	there	there	EX
cord-004222-z4butywi	126	6	is	be	VBZ
cord-004222-z4butywi	126	7	a	a	DT
cord-004222-z4butywi	126	8	much	much	RB
cord-004222-z4butywi	126	9	higher	high	JJR
cord-004222-z4butywi	126	10	frequency	frequency	NN
cord-004222-z4butywi	126	11	of	of	IN
cord-004222-z4butywi	126	12	'	'	``
cord-004222-z4butywi	126	13	public	public	JJ
cord-004222-z4butywi	126	14	clonotypes	clonotype	NNS
cord-004222-z4butywi	126	15	'	'	POS
cord-004222-z4butywi	126	16	or	or	CC
cord-004222-z4butywi	126	17	clonotypes	clonotype	NNS
cord-004222-z4butywi	126	18	shared	share	VBN
cord-004222-z4butywi	126	19	between	between	IN
cord-004222-z4butywi	126	20	members	member	NNS
cord-004222-z4butywi	126	21	of	of	IN
cord-004222-z4butywi	126	22	this	this	DT
cord-004222-z4butywi	126	23	species	specie	NNS
cord-004222-z4butywi	126	24	than	than	IN
cord-004222-z4butywi	126	25	previously	previously	RB
cord-004222-z4butywi	126	26	reported	report	VBN
cord-004222-z4butywi	126	27	in	in	IN
cord-004222-z4butywi	126	28	humans	human	NNS
cord-004222-z4butywi	126	29	13	13	CD
cord-004222-z4butywi	126	30	,	,	,
cord-004222-z4butywi	126	31	32	32	CD
cord-004222-z4butywi	126	32	.	.	.
cord-004222-z4butywi	127	1	Lower	low	JJR
cord-004222-z4butywi	127	2	sequence	sequence	NN
cord-004222-z4butywi	127	3	diversity	diversity	NN
cord-004222-z4butywi	127	4	combined	combine	VBN
cord-004222-z4butywi	127	5	with	with	IN
cord-004222-z4butywi	127	6	identical	identical	JJ
cord-004222-z4butywi	127	7	genetic	genetic	JJ
cord-004222-z4butywi	127	8	background	background	NN
cord-004222-z4butywi	127	9	and	and	CC
cord-004222-z4butywi	127	10	highly	highly	RB
cord-004222-z4butywi	127	11	similar	similar	JJ
cord-004222-z4butywi	127	12	gene	gene	NN
cord-004222-z4butywi	127	13	usage	usage	NN
cord-004222-z4butywi	127	14	are	be	VBP
cord-004222-z4butywi	127	15	possible	possible	JJ
cord-004222-z4butywi	127	16	reasons	reason	NNS
cord-004222-z4butywi	127	17	for	for	IN
cord-004222-z4butywi	127	18	this	this	DT
cord-004222-z4butywi	127	19	result	result	NN
cord-004222-z4butywi	127	20	.	.	.
cord-004222-z4butywi	128	1	In	in	IN
cord-004222-z4butywi	128	2	summary	summary	NN
cord-004222-z4butywi	128	3	,	,	,
cord-004222-z4butywi	128	4	we	-PRON-	PRP
cord-004222-z4butywi	128	5	have	have	VBP
cord-004222-z4butywi	128	6	determined	determine	VBN
cord-004222-z4butywi	128	7	specific	specific	JJ
cord-004222-z4butywi	128	8	differences	difference	NNS
cord-004222-z4butywi	128	9	between	between	IN
cord-004222-z4butywi	128	10	the	the	DT
cord-004222-z4butywi	128	11	OmniRat	OmniRat	NNP
cord-004222-z4butywi	128	12	and	and	CC
cord-004222-z4butywi	128	13	human	human	JJ
cord-004222-z4butywi	128	14	antibody	antibody	NN
cord-004222-z4butywi	128	15	repertoires	repertoire	NNS
cord-004222-z4butywi	128	16	which	which	WDT
cord-004222-z4butywi	128	17	must	must	MD
cord-004222-z4butywi	128	18	be	be	VB
cord-004222-z4butywi	128	19	taken	take	VBN
cord-004222-z4butywi	128	20	into	into	IN
cord-004222-z4butywi	128	21	careful	careful	JJ
cord-004222-z4butywi	128	22	consideration	consideration	NN
cord-004222-z4butywi	128	23	when	when	WRB
cord-004222-z4butywi	128	24	evaluating	evaluate	VBG
cord-004222-z4butywi	128	25	an	an	DT
cord-004222-z4butywi	128	26	antibody	antibody	NN
cord-004222-z4butywi	128	27	response	response	NN
cord-004222-z4butywi	128	28	in	in	IN
cord-004222-z4butywi	128	29	order	order	NN
cord-004222-z4butywi	128	30	to	to	TO
cord-004222-z4butywi	128	31	make	make	VB
cord-004222-z4butywi	128	32	predictions	prediction	NNS
cord-004222-z4butywi	128	33	for	for	IN
cord-004222-z4butywi	128	34	human	human	JJ
cord-004222-z4butywi	128	35	subjects	subject	NNS
cord-004222-z4butywi	128	36	.	.	.
cord-004222-z4butywi	129	1	We	-PRON-	PRP
cord-004222-z4butywi	129	2	have	have	VBP
cord-004222-z4butywi	129	3	also	also	RB
cord-004222-z4butywi	129	4	shown	show	VBN
cord-004222-z4butywi	129	5	that	that	IN
cord-004222-z4butywi	129	6	this	this	DT
cord-004222-z4butywi	129	7	animal	animal	NN
cord-004222-z4butywi	129	8	's	's	POS
cord-004222-z4butywi	129	9	antibodies	antibody	NNS
cord-004222-z4butywi	129	10	show	show	VBP
cord-004222-z4butywi	129	11	signs	sign	NNS
cord-004222-z4butywi	129	12	of	of	IN
cord-004222-z4butywi	129	13	class	class	NN
cord-004222-z4butywi	129	14	switch	switch	NN
cord-004222-z4butywi	129	15	recombination	recombination	NN
cord-004222-z4butywi	129	16	,	,	,
cord-004222-z4butywi	129	17	somatic	somatic	JJ
cord-004222-z4butywi	129	18	hypermutation	hypermutation	NN
cord-004222-z4butywi	129	19	and	and	CC
cord-004222-z4butywi	129	20	large	large	JJ
cord-004222-z4butywi	129	21	diversity	diversity	NN
cord-004222-z4butywi	129	22	supporting	support	VBG
cord-004222-z4butywi	129	23	its	-PRON-	PRP$
cord-004222-z4butywi	129	24	value	value	NN
cord-004222-z4butywi	129	25	for	for	IN
cord-004222-z4butywi	129	26	the	the	DT
cord-004222-z4butywi	129	27	discovery	discovery	NN
cord-004222-z4butywi	129	28	of	of	IN
cord-004222-z4butywi	129	29	monoclonal	monoclonal	JJ
cord-004222-z4butywi	129	30	antibodies	antibody	NNS
cord-004222-z4butywi	129	31	to	to	IN
cord-004222-z4butywi	129	32	targets	target	NNS
cord-004222-z4butywi	129	33	that	that	WDT
cord-004222-z4butywi	129	34	may	may	MD
cord-004222-z4butywi	129	35	not	not	RB
cord-004222-z4butywi	129	36	be	be	VB
cord-004222-z4butywi	129	37	immunogenic	immunogenic	JJ
cord-004222-z4butywi	129	38	in	in	IN
cord-004222-z4butywi	129	39	other	other	JJ
cord-004222-z4butywi	129	40	models	model	NNS
cord-004222-z4butywi	129	41	.	.	.
cord-004222-z4butywi	130	1	Even	even	RB
cord-004222-z4butywi	130	2	though	though	IN
cord-004222-z4butywi	130	3	a	a	DT
cord-004222-z4butywi	130	4	high	high	JJ
cord-004222-z4butywi	130	5	degree	degree	NN
cord-004222-z4butywi	130	6	of	of	IN
cord-004222-z4butywi	130	7	variation	variation	NN
cord-004222-z4butywi	130	8	exists	exist	VBZ
cord-004222-z4butywi	130	9	,	,	,
cord-004222-z4butywi	130	10	we	-PRON-	PRP
cord-004222-z4butywi	130	11	still	still	RB
cord-004222-z4butywi	130	12	found	find	VBD
cord-004222-z4butywi	130	13	many	many	JJ
cord-004222-z4butywi	130	14	clonotypes	clonotype	NNS
cord-004222-z4butywi	130	15	to	to	TO
cord-004222-z4butywi	130	16	be	be	VB
cord-004222-z4butywi	130	17	shared	share	VBN
cord-004222-z4butywi	130	18	between	between	IN
cord-004222-z4butywi	130	19	the	the	DT
cord-004222-z4butywi	130	20	species	species	NN
cord-004222-z4butywi	130	21	pools	pool	NNS
cord-004222-z4butywi	130	22	.	.	.
cord-004222-z4butywi	131	1	Finally	finally	RB
cord-004222-z4butywi	131	2	,	,	,
cord-004222-z4butywi	131	3	more	more	JJR
cord-004222-z4butywi	131	4	studies	study	NNS
cord-004222-z4butywi	131	5	will	will	MD
cord-004222-z4butywi	131	6	need	need	VB
cord-004222-z4butywi	131	7	to	to	TO
cord-004222-z4butywi	131	8	be	be	VB
cord-004222-z4butywi	131	9	done	do	VBN
cord-004222-z4butywi	131	10	in	in	IN
cord-004222-z4butywi	131	11	order	order	NN
cord-004222-z4butywi	131	12	to	to	TO
cord-004222-z4butywi	131	13	characterize	characterize	VB
cord-004222-z4butywi	131	14	OmniRat	OmniRat	NNP
cord-004222-z4butywi	131	15	serum	serum	NN
cord-004222-z4butywi	131	16	and	and	CC
cord-004222-z4butywi	131	17	memory	memory	NN
cord-004222-z4butywi	131	18	B	b	NN
cord-004222-z4butywi	131	19	cell	cell	NN
cord-004222-z4butywi	131	20	responses	response	NNS
cord-004222-z4butywi	131	21	to	to	IN
cord-004222-z4butywi	131	22	immunogens	immunogen	NNS
cord-004222-z4butywi	131	23	.	.	.
cord-004222-z4butywi	132	1	Next	next	JJ
cord-004222-z4butywi	132	2	-	-	HYPH
cord-004222-z4butywi	132	3	generation	generation	NN
cord-004222-z4butywi	132	4	sequencing	sequencing	NN
cord-004222-z4butywi	132	5	of	of	IN
cord-004222-z4butywi	132	6	OmniRat	omnirat	NN
cord-004222-z4butywi	132	7	antibody	antibody	NN
cord-004222-z4butywi	132	8	repertoires	repertoire	NNS
cord-004222-z4butywi	132	9	.	.	.
cord-004222-z4butywi	133	1	Total	Total	NNP
cord-004222-z4butywi	133	2	RNA	RNA	NNP
cord-004222-z4butywi	133	3	from	from	IN
cord-004222-z4butywi	133	4	spleens	spleen	NNS
cord-004222-z4butywi	133	5	and	and	CC
cord-004222-z4butywi	133	6	lymph	lymph	NN
cord-004222-z4butywi	133	7	nodes	node	NNS
cord-004222-z4butywi	133	8	was	be	VBD
cord-004222-z4butywi	133	9	extracted	extract	VBN
cord-004222-z4butywi	133	10	(	(	-LRB-
cord-004222-z4butywi	133	11	RNeasy	RNeasy	NNP
cord-004222-z4butywi	133	12	Maxi	Maxi	NNP
cord-004222-z4butywi	133	13	Kit	kit	NN
cord-004222-z4butywi	133	14	,	,	,
cord-004222-z4butywi	133	15	Qiagen	Qiagen	NNP
cord-004222-z4butywi	133	16	)	)	-RRB-
cord-004222-z4butywi	133	17	from	from	IN
cord-004222-z4butywi	133	18	each	each	DT
cord-004222-z4butywi	133	19	unimmunized	unimmunized	JJ
cord-004222-z4butywi	133	20	heavy	heavy	JJ
cord-004222-z4butywi	133	21	chain	chain	NN
cord-004222-z4butywi	133	22	and	and	CC
cord-004222-z4butywi	133	23	kappa	kappa	NN
cord-004222-z4butywi	133	24	chain	chain	NN
cord-004222-z4butywi	134	1	only	only	RB
cord-004222-z4butywi	134	2	transgenic	transgenic	JJ
cord-004222-z4butywi	134	3	rat	rat	NN
cord-004222-z4butywi	134	4	(	(	-LRB-
cord-004222-z4butywi	134	5	OmniRat	omnirat	UH
cord-004222-z4butywi	134	6	,	,	,
cord-004222-z4butywi	134	7	Open	Open	NNP
cord-004222-z4butywi	134	8	Monoclonal	Monoclonal	NNP
cord-004222-z4butywi	134	9	Technology	Technology	NNP
cord-004222-z4butywi	134	10	Inc.	Inc.	NNP
cord-004222-z4butywi	134	11	,	,	,
cord-004222-z4butywi	134	12	Palo	Palo	NNP
cord-004222-z4butywi	134	13	Alto	Alto	NNP
cord-004222-z4butywi	134	14	,	,	,
cord-004222-z4butywi	134	15	CA	CA	NNP
cord-004222-z4butywi	134	16	,	,	,
cord-004222-z4butywi	134	17	USA	USA	NNP
cord-004222-z4butywi	134	18	)	)	-RRB-
cord-004222-z4butywi	134	19	and	and	CC
cord-004222-z4butywi	134	20	antibody	antibody	NN
cord-004222-z4butywi	134	21	sequences	sequence	NNS
cord-004222-z4butywi	134	22	were	be	VBD
cord-004222-z4butywi	134	23	amplified	amplify	VBN
cord-004222-z4butywi	134	24	as	as	IN
cord-004222-z4butywi	134	25	previously	previously	RB
cord-004222-z4butywi	134	26	described	describe	VBN
cord-004222-z4butywi	134	27	13	13	CD
cord-004222-z4butywi	134	28	except	except	IN
cord-004222-z4butywi	134	29	for	for	IN
cord-004222-z4butywi	134	30	different	different	JJ
cord-004222-z4butywi	134	31	primers	primer	NNS
cord-004222-z4butywi	134	32	used	use	VBN
cord-004222-z4butywi	134	33	during	during	IN
cord-004222-z4butywi	134	34	reverse	reverse	JJ
cord-004222-z4butywi	134	35	transcription	transcription	NN
cord-004222-z4butywi	134	36	(	(	-LRB-
cord-004222-z4butywi	134	37	Table	table	NN
cord-004222-z4butywi	134	38	S2	S2	NNP
cord-004222-z4butywi	134	39	)	)	-RRB-
cord-004222-z4butywi	134	40	.	.	.
cord-004222-z4butywi	135	1	We	-PRON-	PRP
cord-004222-z4butywi	135	2	chose	choose	VBD
cord-004222-z4butywi	135	3	to	to	TO
cord-004222-z4butywi	135	4	interrogate	interrogate	VB
cord-004222-z4butywi	135	5	the	the	DT
cord-004222-z4butywi	135	6	antibody	antibody	NN
cord-004222-z4butywi	135	7	repertoires	repertoire	NNS
cord-004222-z4butywi	135	8	found	find	VBN
cord-004222-z4butywi	135	9	in	in	IN
cord-004222-z4butywi	135	10	secondary	secondary	JJ
cord-004222-z4butywi	135	11	lymphoid	lymphoid	JJ
cord-004222-z4butywi	135	12	organs	organ	NNS
cord-004222-z4butywi	135	13	as	as	IN
cord-004222-z4butywi	135	14	opposed	oppose	VBN
cord-004222-z4butywi	135	15	to	to	IN
cord-004222-z4butywi	135	16	peripheral	peripheral	JJ
cord-004222-z4butywi	135	17	blood	blood	NN
cord-004222-z4butywi	135	18	due	due	IN
cord-004222-z4butywi	135	19	to	to	IN
cord-004222-z4butywi	135	20	the	the	DT
cord-004222-z4butywi	135	21	higher	high	JJR
cord-004222-z4butywi	135	22	number	number	NN
cord-004222-z4butywi	135	23	of	of	IN
cord-004222-z4butywi	135	24	B	b	NN
cord-004222-z4butywi	135	25	cells	cell	NNS
cord-004222-z4butywi	135	26	.	.	.
cord-004222-z4butywi	136	1	Correct	correct	JJ
cord-004222-z4butywi	136	2	PCR	PCR	NNP
cord-004222-z4butywi	136	3	product	product	NN
cord-004222-z4butywi	136	4	sizes	size	NNS
cord-004222-z4butywi	136	5	were	be	VBD
cord-004222-z4butywi	136	6	verified	verify	VBN
cord-004222-z4butywi	136	7	on	on	IN
cord-004222-z4butywi	136	8	an	an	DT
cord-004222-z4butywi	136	9	agarose	agarose	JJ
cord-004222-z4butywi	136	10	gel	gel	NN
cord-004222-z4butywi	136	11	(	(	-LRB-
cord-004222-z4butywi	136	12	E	e	NN
cord-004222-z4butywi	136	13	-	-	HYPH
cord-004222-z4butywi	136	14	Gel	gel	NN
cord-004222-z4butywi	136	15	EX	EX	NNP
cord-004222-z4butywi	136	16	;	;	:
cord-004222-z4butywi	136	17	Invitrogen	Invitrogen	NNP
cord-004222-z4butywi	136	18	)	)	-RRB-
cord-004222-z4butywi	136	19	and	and	CC
cord-004222-z4butywi	136	20	quantified	quantify	VBN
cord-004222-z4butywi	136	21	with	with	IN
cord-004222-z4butywi	136	22	fluorometry	fluorometry	NN
cord-004222-z4butywi	136	23	(	(	-LRB-
cord-004222-z4butywi	136	24	Qubit	qubit	NN
cord-004222-z4butywi	136	25	;	;	:
cord-004222-z4butywi	136	26	Life	Life	NNP
cord-004222-z4butywi	136	27	Technologies	Technologies	NNPS
cord-004222-z4butywi	136	28	)	)	-RRB-
cord-004222-z4butywi	136	29	,	,	,
cord-004222-z4butywi	136	30	pooled	pool	VBN
cord-004222-z4butywi	136	31	at	at	IN
cord-004222-z4butywi	136	32	approximately	approximately	RB
cord-004222-z4butywi	136	33	equimolar	equimolar	JJ
cord-004222-z4butywi	136	34	concentrations	concentration	NNS
cord-004222-z4butywi	136	35	and	and	CC
cord-004222-z4butywi	136	36	each	each	DT
cord-004222-z4butywi	136	37	sample	sample	NN
cord-004222-z4butywi	136	38	pool	pool	NN
cord-004222-z4butywi	136	39	was	be	VBD
cord-004222-z4butywi	136	40	re	re	VBN
cord-004222-z4butywi	136	41	-	-	VBN
cord-004222-z4butywi	136	42	quantified	quantify	VBN
cord-004222-z4butywi	136	43	before	before	IN
cord-004222-z4butywi	136	44	sequencing	sequence	VBG
cord-004222-z4butywi	136	45	on	on	IN
cord-004222-z4butywi	136	46	an	an	DT
cord-004222-z4butywi	136	47	Illumina	Illumina	NNP
cord-004222-z4butywi	136	48	MiSeq	MiSeq	NNP
cord-004222-z4butywi	136	49	(	(	-LRB-
cord-004222-z4butywi	136	50	MiSeq	MiSeq	NNP
cord-004222-z4butywi	136	51	Reagent	Reagent	NNP
cord-004222-z4butywi	136	52	Kit	kit	NN
cord-004222-z4butywi	136	53	v3	v3	NN
cord-004222-z4butywi	136	54	,	,	,
cord-004222-z4butywi	136	55	600-cycle	600-cycle	CD
cord-004222-z4butywi	136	56	)	)	-RRB-
cord-004222-z4butywi	136	57	.	.	.
cord-004222-z4butywi	137	1	All	all	DT
cord-004222-z4butywi	137	2	animal	animal	NN
cord-004222-z4butywi	137	3	experiments	experiment	NNS
cord-004222-z4butywi	137	4	were	be	VBD
cord-004222-z4butywi	137	5	conducted	conduct	VBN
cord-004222-z4butywi	137	6	in	in	IN
cord-004222-z4butywi	137	7	accordance	accordance	NN
cord-004222-z4butywi	137	8	with	with	IN
cord-004222-z4butywi	137	9	the	the	DT
cord-004222-z4butywi	137	10	Institutional	Institutional	NNP
cord-004222-z4butywi	137	11	Animal	Animal	NNP
cord-004222-z4butywi	137	12	Care	Care	NNP
cord-004222-z4butywi	137	13	and	and	CC
cord-004222-z4butywi	137	14	Use	Use	NNP
cord-004222-z4butywi	137	15	Committee	Committee	NNP
cord-004222-z4butywi	137	16	of	of	IN
cord-004222-z4butywi	137	17	Scripps	Scripps	NNP
cord-004222-z4butywi	137	18	Research	Research	NNP
cord-004222-z4butywi	137	19	and	and	CC
cord-004222-z4butywi	137	20	approved	approve	VBN
cord-004222-z4butywi	137	21	by	by	IN
cord-004222-z4butywi	137	22	the	the	DT
cord-004222-z4butywi	137	23	Institutional	Institutional	NNP
cord-004222-z4butywi	137	24	Research	Research	NNP
cord-004222-z4butywi	137	25	Boards	Boards	NNPS
cord-004222-z4butywi	137	26	of	of	IN
cord-004222-z4butywi	137	27	Scripps	Scripps	NNP
cord-004222-z4butywi	137	28	Research	Research	NNP
cord-004222-z4butywi	137	29	.	.	.
cord-004222-z4butywi	138	1	(	(	-LRB-
cord-004222-z4butywi	138	2	d	d	LS
cord-004222-z4butywi	138	3	)	)	-RRB-
cord-004222-z4butywi	138	4	Distribution	distribution	NN
cord-004222-z4butywi	138	5	of	of	IN
cord-004222-z4butywi	138	6	VH	VH	NNP
cord-004222-z4butywi	138	7	gene	gene	NN
cord-004222-z4butywi	138	8	family	family	NN
cord-004222-z4butywi	138	9	usage	usage	NN
cord-004222-z4butywi	138	10	for	for	IN
cord-004222-z4butywi	138	11	unshared	unshared	JJ
cord-004222-z4butywi	138	12	clonotypes	clonotype	NNS
cord-004222-z4butywi	138	13	from	from	IN
cord-004222-z4butywi	138	14	the	the	DT
cord-004222-z4butywi	138	15	animal	animal	NN
cord-004222-z4butywi	138	16	pool	pool	NN
cord-004222-z4butywi	138	17	(	(	-LRB-
cord-004222-z4butywi	138	18	black	black	JJ
cord-004222-z4butywi	138	19	)	)	-RRB-
cord-004222-z4butywi	138	20	or	or	CC
cord-004222-z4butywi	138	21	clonotypes	clonotype	NNS
cord-004222-z4butywi	138	22	shared	share	VBN
cord-004222-z4butywi	138	23	by	by	IN
cord-004222-z4butywi	138	24	both	both	DT
cord-004222-z4butywi	138	25	species	specie	NNS
cord-004222-z4butywi	138	26	pool	pool	NN
cord-004222-z4butywi	138	27	(	(	-LRB-
cord-004222-z4butywi	138	28	red	red	NN
cord-004222-z4butywi	138	29	)	)	-RRB-
cord-004222-z4butywi	138	30	.	.	.
cord-004222-z4butywi	139	1	(	(	-LRB-
cord-004222-z4butywi	139	2	e	e	NNP
cord-004222-z4butywi	139	3	,	,	,
cord-004222-z4butywi	139	4	f	f	LS
cord-004222-z4butywi	139	5	)	)	-RRB-
cord-004222-z4butywi	139	6	Sequence	sequence	NN
cord-004222-z4butywi	139	7	logos	logo	NNS
cord-004222-z4butywi	139	8	of	of	IN
cord-004222-z4butywi	139	9	the	the	DT
cord-004222-z4butywi	139	10	CDRH3s	CDRH3s	NNP
cord-004222-z4butywi	139	11	encoded	encode	VBN
cord-004222-z4butywi	139	12	by	by	IN
cord-004222-z4butywi	139	13	shared	shared	JJ
cord-004222-z4butywi	139	14	and	and	CC
cord-004222-z4butywi	139	15	unshared	unshared	JJ
cord-004222-z4butywi	139	16	clonotypes	clonotype	NNS
cord-004222-z4butywi	139	17	of	of	IN
cord-004222-z4butywi	139	18	length	length	NN
cord-004222-z4butywi	139	19	8	8	CD
cord-004222-z4butywi	139	20	(	(	-LRB-
cord-004222-z4butywi	139	21	e	e	NN
cord-004222-z4butywi	139	22	)	)	-RRB-
cord-004222-z4butywi	139	23	or	or	CC
cord-004222-z4butywi	139	24	13	13	CD
cord-004222-z4butywi	139	25	(	(	-LRB-
cord-004222-z4butywi	139	26	f	f	NNP
cord-004222-z4butywi	139	27	)	)	-RRB-
cord-004222-z4butywi	139	28	.	.	.
cord-004222-z4butywi	140	1	Head	head	NN
cord-004222-z4butywi	140	2	-	-	HYPH
cord-004222-z4butywi	140	3	region	region	NN
cord-004222-z4butywi	140	4	amino	amino	NN
cord-004222-z4butywi	140	5	acid	acid	NN
cord-004222-z4butywi	140	6	coloring	coloring	NN
cord-004222-z4butywi	140	7	:	:	:
cord-004222-z4butywi	140	8	polar	polar	JJ
cord-004222-z4butywi	140	9	amino	amino	JJ
cord-004222-z4butywi	140	10	acids	acid	NNS
cord-004222-z4butywi	140	11	(	(	-LRB-
cord-004222-z4butywi	140	12	GSTYCQN	GSTYCQN	NNP
cord-004222-z4butywi	140	13	)	)	-RRB-
cord-004222-z4butywi	140	14	are	be	VBP
cord-004222-z4butywi	140	15	green	green	JJ
cord-004222-z4butywi	140	16	;	;	:
cord-004222-z4butywi	140	17	basic	basic	JJ
cord-004222-z4butywi	140	18	amino	amino	NN
cord-004222-z4butywi	140	19	acids	acid	NNS
cord-004222-z4butywi	140	20	(	(	-LRB-
cord-004222-z4butywi	140	21	KRH	KRH	NNP
cord-004222-z4butywi	140	22	)	)	-RRB-
cord-004222-z4butywi	140	23	are	be	VBP
cord-004222-z4butywi	140	24	blue	blue	JJ
cord-004222-z4butywi	140	25	;	;	:
cord-004222-z4butywi	140	26	acidic	acidic	JJ
cord-004222-z4butywi	140	27	amino	amino	NN
cord-004222-z4butywi	140	28	acids	acid	NNS
cord-004222-z4butywi	140	29	(	(	-LRB-
cord-004222-z4butywi	140	30	DE	DE	NNP
cord-004222-z4butywi	140	31	)	)	-RRB-
cord-004222-z4butywi	140	32	are	be	VBP
cord-004222-z4butywi	140	33	red	red	JJ
cord-004222-z4butywi	140	34	;	;	:
cord-004222-z4butywi	140	35	and	and	CC
cord-004222-z4butywi	140	36	hydrophobic	hydrophobic	JJ
cord-004222-z4butywi	140	37	amino	amino	JJ
cord-004222-z4butywi	140	38	acids	acid	NNS
cord-004222-z4butywi	140	39	(	(	-LRB-
cord-004222-z4butywi	140	40	AVLIPWFM	AVLIPWFM	NNP
cord-004222-z4butywi	140	41	)	)	-RRB-
cord-004222-z4butywi	140	42	are	be	VBP
cord-004222-z4butywi	140	43	black	black	JJ
cord-004222-z4butywi	140	44	.	.	.
cord-004222-z4butywi	141	1	All	all	DT
cord-004222-z4butywi	141	2	torso	torso	JJ
cord-004222-z4butywi	141	3	residues	residue	NNS
cord-004222-z4butywi	141	4	are	be	VBP
cord-004222-z4butywi	141	5	gray	gray	JJ
cord-004222-z4butywi	141	6	.	.	.
cord-004222-z4butywi	142	1	Murine	murine	JJ
cord-004222-z4butywi	142	2	antibody	antibody	NN
cord-004222-z4butywi	142	3	responses	response	NNS
cord-004222-z4butywi	142	4	to	to	IN
cord-004222-z4butywi	142	5	cleaved	cleave	VBD
cord-004222-z4butywi	142	6	soluble	soluble	JJ
cord-004222-z4butywi	142	7	HIV-1	HIV-1	NNP
cord-004222-z4butywi	142	8	envelope	envelope	NN
cord-004222-z4butywi	142	9	trimers	trimer	NNS
cord-004222-z4butywi	142	10	are	be	VBP
cord-004222-z4butywi	142	11	highly	highly	RB
cord-004222-z4butywi	142	12	restricted	restrict	VBN
cord-004222-z4butywi	142	13	in	in	IN
cord-004222-z4butywi	142	14	specificity	specificity	NN
cord-004222-z4butywi	142	15	Rational	rational	JJ
cord-004222-z4butywi	142	16	HIV	HIV	NNP
cord-004222-z4butywi	142	17	immunogen	immunogen	NN
cord-004222-z4butywi	142	18	design	design	NN
cord-004222-z4butywi	142	19	to	to	TO
cord-004222-z4butywi	142	20	target	target	VB
cord-004222-z4butywi	142	21	specific	specific	JJ
cord-004222-z4butywi	142	22	germline	germline	NN
cord-004222-z4butywi	142	23	B	b	NN
cord-004222-z4butywi	142	24	cell	cell	NN
cord-004222-z4butywi	142	25	receptors	receptor	NNS
cord-004222-z4butywi	142	26	Priming	prime	VBG
cord-004222-z4butywi	142	27	HIV-1	HIV-1	NNP
cord-004222-z4butywi	142	28	broadly	broadly	RB
cord-004222-z4butywi	142	29	neutralizing	neutralize	VBG
cord-004222-z4butywi	142	30	antibody	antibody	NN
cord-004222-z4butywi	142	31	precursors	precursor	NNS
cord-004222-z4butywi	142	32	in	in	IN
cord-004222-z4butywi	142	33	human	human	JJ
cord-004222-z4butywi	142	34	ig	ig	JJ
cord-004222-z4butywi	142	35	loci	locus	NNS
cord-004222-z4butywi	142	36	transgenic	transgenic	JJ
cord-004222-z4butywi	142	37	mice	mouse	NNS
cord-004222-z4butywi	143	1	Bacterially	bacterially	RB
cord-004222-z4butywi	143	2	derived	derive	VBN
cord-004222-z4butywi	143	3	synthetic	synthetic	JJ
cord-004222-z4butywi	143	4	mimetics	mimetic	NNS
cord-004222-z4butywi	143	5	of	of	IN
cord-004222-z4butywi	143	6	mammalian	mammalian	JJ
cord-004222-z4butywi	143	7	oligomannose	oligomannose	NNP
cord-004222-z4butywi	143	8	prime	prime	JJ
cord-004222-z4butywi	143	9	antibody	antibody	NN
cord-004222-z4butywi	143	10	responses	response	NNS
cord-004222-z4butywi	143	11	that	that	WDT
cord-004222-z4butywi	143	12	neutralize	neutralize	VBP
cord-004222-z4butywi	143	13	HIV	HIV	NNP
cord-004222-z4butywi	143	14	infectivity	infectivity	NN
cord-004222-z4butywi	143	15	A	a	DT
cord-004222-z4butywi	143	16	repertoire	repertoire	NN
cord-004222-z4butywi	143	17	of	of	IN
cord-004222-z4butywi	143	18	monoclonal	monoclonal	JJ
cord-004222-z4butywi	143	19	antibodies	antibody	NNS
cord-004222-z4butywi	143	20	with	with	IN
cord-004222-z4butywi	143	21	human	human	JJ
cord-004222-z4butywi	143	22	heavy	heavy	JJ
cord-004222-z4butywi	143	23	chains	chain	NNS
cord-004222-z4butywi	143	24	from	from	IN
cord-004222-z4butywi	143	25	transgenic	transgenic	JJ
cord-004222-z4butywi	143	26	mice	mouse	NNS
cord-004222-z4butywi	143	27	Antigen	antigen	NN
cord-004222-z4butywi	143	28	-	-	HYPH
cord-004222-z4butywi	143	29	specific	specific	JJ
cord-004222-z4butywi	143	30	human	human	JJ
cord-004222-z4butywi	143	31	monoclonal	monoclonal	JJ
cord-004222-z4butywi	143	32	antibodies	antibody	NNS
cord-004222-z4butywi	143	33	from	from	IN
cord-004222-z4butywi	143	34	mice	mouse	NNS
cord-004222-z4butywi	143	35	engineered	engineer	VBN
cord-004222-z4butywi	143	36	with	with	IN
cord-004222-z4butywi	143	37	human	human	JJ
cord-004222-z4butywi	143	38	ig	ig	NN
cord-004222-z4butywi	143	39	heavy	heavy	NN
cord-004222-z4butywi	143	40	and	and	CC
cord-004222-z4butywi	143	41	light	light	JJ
cord-004222-z4butywi	143	42	chain	chain	NN
cord-004222-z4butywi	143	43	YACs	yac	NNS
cord-004222-z4butywi	143	44	Antigen	antigen	NN
cord-004222-z4butywi	143	45	-	-	HYPH
cord-004222-z4butywi	143	46	specific	specific	JJ
cord-004222-z4butywi	143	47	human	human	JJ
cord-004222-z4butywi	143	48	antibodies	antibody	NNS
cord-004222-z4butywi	143	49	from	from	IN
cord-004222-z4butywi	143	50	mice	mouse	NNS
cord-004222-z4butywi	143	51	comprising	comprise	VBG
cord-004222-z4butywi	143	52	four	four	CD
cord-004222-z4butywi	143	53	distinct	distinct	JJ
cord-004222-z4butywi	143	54	genetic	genetic	JJ
cord-004222-z4butywi	143	55	modifications	modification	NNS
cord-004222-z4butywi	143	56	Human	human	JJ
cord-004222-z4butywi	143	57	antibody	antibody	NN
cord-004222-z4butywi	143	58	production	production	NN
cord-004222-z4butywi	143	59	in	in	IN
cord-004222-z4butywi	143	60	transgenic	transgenic	JJ
cord-004222-z4butywi	143	61	animals	animal	NNS
cord-004222-z4butywi	143	62	Transgenic	transgenic	JJ
cord-004222-z4butywi	143	63	mouse	mouse	NN
cord-004222-z4butywi	143	64	strains	strain	NNS
cord-004222-z4butywi	143	65	as	as	IN
cord-004222-z4butywi	143	66	platforms	platform	NNS
cord-004222-z4butywi	143	67	for	for	IN
cord-004222-z4butywi	143	68	the	the	DT
cord-004222-z4butywi	143	69	successful	successful	JJ
cord-004222-z4butywi	143	70	discovery	discovery	NN
cord-004222-z4butywi	143	71	and	and	CC
cord-004222-z4butywi	143	72	development	development	NN
cord-004222-z4butywi	143	73	of	of	IN
cord-004222-z4butywi	143	74	human	human	JJ
cord-004222-z4butywi	143	75	therapeutic	therapeutic	JJ
cord-004222-z4butywi	143	76	monoclonal	monoclonal	JJ
cord-004222-z4butywi	143	77	antibodies	antibody	NNS
cord-004222-z4butywi	143	78	Mechanisms	Mechanisms	NNPS
cord-004222-z4butywi	143	79	of	of	IN
cord-004222-z4butywi	143	80	central	central	JJ
cord-004222-z4butywi	143	81	tolerance	tolerance	NN
cord-004222-z4butywi	143	82	for	for	IN
cord-004222-z4butywi	143	83	B	b	NN
cord-004222-z4butywi	143	84	cells	cell	NNS
cord-004222-z4butywi	143	85	High	high	JJ
cord-004222-z4butywi	143	86	-	-	HYPH
cord-004222-z4butywi	143	87	affinity	affinity	NN
cord-004222-z4butywi	143	88	IgG	igg	NN
cord-004222-z4butywi	143	89	antibodies	antibody	NNS
cord-004222-z4butywi	143	90	develop	develop	VBP
cord-004222-z4butywi	143	91	naturally	naturally	RB
cord-004222-z4butywi	143	92	in	in	IN
cord-004222-z4butywi	143	93	ig	ig	JJ
cord-004222-z4butywi	143	94	-	-	HYPH
cord-004222-z4butywi	143	95	knockout	knockout	NN
cord-004222-z4butywi	143	96	rats	rat	NNS
cord-004222-z4butywi	143	97	carrying	carry	VBG
cord-004222-z4butywi	143	98	germline	germline	JJ
cord-004222-z4butywi	143	99	human	human	JJ
cord-004222-z4butywi	143	100	IgH	igh	NN
cord-004222-z4butywi	143	101	/	/	,
cord-004222-z4butywi	143	102	Igκ	Igκ	NNP
cord-004222-z4butywi	143	103	/	/	SYM
cord-004222-z4butywi	143	104	Igλ	Igλ	NNP
cord-004222-z4butywi	143	105	loci	locus	NNS
cord-004222-z4butywi	143	106	bearing	bear	VBG
cord-004222-z4butywi	143	107	the	the	DT
cord-004222-z4butywi	143	108	rat	rat	NN
cord-004222-z4butywi	143	109	CH	CH	NNP
cord-004222-z4butywi	143	110	region	region	NN
cord-004222-z4butywi	143	111	Human	human	JJ
cord-004222-z4butywi	143	112	antibody	antibody	NN
cord-004222-z4butywi	143	113	expression	expression	NN
cord-004222-z4butywi	143	114	in	in	IN
cord-004222-z4butywi	143	115	transgenic	transgenic	JJ
cord-004222-z4butywi	143	116	rats	rat	NNS
cord-004222-z4butywi	143	117	:	:	:
cord-004222-z4butywi	144	1	comparison	comparison	NN
cord-004222-z4butywi	144	2	of	of	IN
cord-004222-z4butywi	144	3	chimeric	chimeric	JJ
cord-004222-z4butywi	144	4	IgH	igh	NN
cord-004222-z4butywi	144	5	loci	locus	NNS
cord-004222-z4butywi	144	6	with	with	IN
cord-004222-z4butywi	144	7	human	human	JJ
cord-004222-z4butywi	144	8	VH	VH	NNP
cord-004222-z4butywi	144	9	,	,	,
cord-004222-z4butywi	144	10	D	D	NNP
cord-004222-z4butywi	144	11	and	and	CC
cord-004222-z4butywi	144	12	JH	JH	NNP
cord-004222-z4butywi	144	13	but	but	CC
cord-004222-z4butywi	144	14	bearing	bear	VBG
cord-004222-z4butywi	144	15	different	different	JJ
cord-004222-z4butywi	144	16	rat	rat	NN
cord-004222-z4butywi	144	17	c	c	NN
cord-004222-z4butywi	144	18	-	-	HYPH
cord-004222-z4butywi	144	19	gene	gene	NN
cord-004222-z4butywi	144	20	regions	region	NNS
cord-004222-z4butywi	144	21	Commonality	Commonality	NNP
cord-004222-z4butywi	144	22	despite	despite	IN
cord-004222-z4butywi	144	23	exceptional	exceptional	JJ
cord-004222-z4butywi	144	24	diversity	diversity	NN
cord-004222-z4butywi	144	25	in	in	IN
cord-004222-z4butywi	144	26	the	the	DT
cord-004222-z4butywi	144	27	baseline	baseline	JJ
cord-004222-z4butywi	144	28	human	human	JJ
cord-004222-z4butywi	144	29	antibody	antibody	NN
cord-004222-z4butywi	144	30	repertoire	repertoire	NN
cord-004222-z4butywi	144	31	Clonify	Clonify	NNP
cord-004222-z4butywi	144	32	:	:	:
cord-004222-z4butywi	144	33	unseeded	unseeded	JJ
cord-004222-z4butywi	144	34	antibody	antibody	NN
cord-004222-z4butywi	144	35	lineage	lineage	NN
cord-004222-z4butywi	144	36	assignment	assignment	NN
cord-004222-z4butywi	144	37	from	from	IN
cord-004222-z4butywi	144	38	next	next	JJ
cord-004222-z4butywi	144	39	-	-	HYPH
cord-004222-z4butywi	144	40	generation	generation	NN
cord-004222-z4butywi	144	41	sequencing	sequencing	NN
cord-004222-z4butywi	144	42	data	datum	NNS
cord-004222-z4butywi	144	43	Genetic	genetic	JJ
cord-004222-z4butywi	144	44	measurement	measurement	NN
cord-004222-z4butywi	144	45	of	of	IN
cord-004222-z4butywi	144	46	memory	memory	NN
cord-004222-z4butywi	144	47	b	b	NN
cord-004222-z4butywi	144	48	-	-	HYPH
cord-004222-z4butywi	144	49	cell	cell	NN
cord-004222-z4butywi	144	50	recall	recall	NN
cord-004222-z4butywi	144	51	using	use	VBG
cord-004222-z4butywi	144	52	antibody	antibody	NN
cord-004222-z4butywi	144	53	repertoire	repertoire	NN
cord-004222-z4butywi	144	54	sequencing	sequencing	NN
cord-004222-z4butywi	144	55	Toward	toward	IN
cord-004222-z4butywi	144	56	a	a	DT
cord-004222-z4butywi	144	57	more	more	RBR
cord-004222-z4butywi	144	58	accurate	accurate	JJ
cord-004222-z4butywi	144	59	view	view	NN
cord-004222-z4butywi	144	60	of	of	IN
cord-004222-z4butywi	144	61	human	human	JJ
cord-004222-z4butywi	144	62	b	b	NN
cord-004222-z4butywi	144	63	-	-	HYPH
cord-004222-z4butywi	144	64	cell	cell	NN
cord-004222-z4butywi	144	65	repertoire	repertoire	NN
cord-004222-z4butywi	144	66	by	by	IN
cord-004222-z4butywi	144	67	next	next	JJ
cord-004222-z4butywi	144	68	-	-	HYPH
cord-004222-z4butywi	144	69	generation	generation	NN
cord-004222-z4butywi	144	70	sequencing	sequencing	NN
cord-004222-z4butywi	144	71	,	,	,
cord-004222-z4butywi	144	72	unbiased	unbiased	JJ
cord-004222-z4butywi	144	73	repertoire	repertoire	NN
cord-004222-z4butywi	144	74	capture	capture	NN
cord-004222-z4butywi	144	75	and	and	CC
cord-004222-z4butywi	144	76	single	single	JJ
cord-004222-z4butywi	144	77	-	-	HYPH
cord-004222-z4butywi	144	78	molecule	molecule	NN
cord-004222-z4butywi	144	79	barcoding	barcoding	NN
cord-004222-z4butywi	144	80	Massively	massively	RB
cord-004222-z4butywi	144	81	scalable	scalable	JJ
cord-004222-z4butywi	144	82	genetic	genetic	JJ
cord-004222-z4butywi	144	83	analysis	analysis	NN
cord-004222-z4butywi	144	84	of	of	IN
cord-004222-z4butywi	144	85	antibody	antibody	NN
cord-004222-z4butywi	144	86	repertoires	repertoire	NNS
cord-004222-z4butywi	144	87	Rapid	Rapid	NNP
cord-004222-z4butywi	144	88	and	and	CC
cord-004222-z4butywi	144	89	focused	focus	VBD
cord-004222-z4butywi	144	90	maturation	maturation	NN
cord-004222-z4butywi	144	91	of	of	IN
cord-004222-z4butywi	144	92	a	a	DT
cord-004222-z4butywi	144	93	VRC01-Class	VRC01-Class	NNP
cord-004222-z4butywi	144	94	HIV	HIV	NNP
cord-004222-z4butywi	144	95	broadly	broadly	RB
cord-004222-z4butywi	144	96	neutralizing	neutralize	VBG
cord-004222-z4butywi	144	97	antibody	antibody	NN
cord-004222-z4butywi	144	98	lineage	lineage	NN
cord-004222-z4butywi	144	99	involves	involve	VBZ
cord-004222-z4butywi	144	100	both	both	CC
cord-004222-z4butywi	144	101	binding	binding	NN
cord-004222-z4butywi	144	102	and	and	CC
cord-004222-z4butywi	144	103	accommodation	accommodation	NN
cord-004222-z4butywi	144	104	of	of	IN
cord-004222-z4butywi	144	105	the	the	DT
cord-004222-z4butywi	144	106	N276-Glycan	N276-Glycan	NNP
cord-004222-z4butywi	144	107	HIV-1	HIV-1	NNP
cord-004222-z4butywi	144	108	VACCINES	vaccine	NNS
cord-004222-z4butywi	144	109	.	.	.
cord-004222-z4butywi	145	1	priming	prime	VBG
cord-004222-z4butywi	145	2	a	a	DT
cord-004222-z4butywi	145	3	broadly	broadly	RB
cord-004222-z4butywi	145	4	neutralizing	neutralize	VBG
cord-004222-z4butywi	145	5	antibody	antibody	NN
cord-004222-z4butywi	145	6	response	response	NN
cord-004222-z4butywi	145	7	to	to	IN
cord-004222-z4butywi	145	8	HIV-1	HIV-1	NNP
cord-004222-z4butywi	145	9	using	use	VBG
cord-004222-z4butywi	145	10	a	a	DT
cord-004222-z4butywi	145	11	germline	germline	NN
cord-004222-z4butywi	145	12	targeting	target	VBG
cord-004222-z4butywi	145	13	immunogen	immunogen	NN
cord-004222-z4butywi	145	14	Identification	identification	NN
cord-004222-z4butywi	145	15	of	of	IN
cord-004222-z4butywi	145	16	common	common	JJ
cord-004222-z4butywi	145	17	features	feature	NNS
cord-004222-z4butywi	145	18	in	in	IN
cord-004222-z4butywi	145	19	prototype	prototype	NN
cord-004222-z4butywi	145	20	broadly	broadly	RB
cord-004222-z4butywi	145	21	neutralizing	neutralize	VBG
cord-004222-z4butywi	145	22	antibodies	antibody	NNS
cord-004222-z4butywi	145	23	to	to	IN
cord-004222-z4butywi	145	24	HIV	HIV	NNP
cord-004222-z4butywi	145	25	envelope	envelope	NN
cord-004222-z4butywi	145	26	V2	V2	NNP
cord-004222-z4butywi	145	27	apex	apex	NN
cord-004222-z4butywi	145	28	to	to	TO
cord-004222-z4butywi	145	29	facilitate	facilitate	VB
cord-004222-z4butywi	145	30	vaccine	vaccine	NN
cord-004222-z4butywi	145	31	design	design	NN
cord-004222-z4butywi	145	32	High	high	JJ
cord-004222-z4butywi	145	33	-	-	HYPH
cord-004222-z4butywi	145	34	throughput	throughput	NN
cord-004222-z4butywi	145	35	immune	immune	JJ
cord-004222-z4butywi	145	36	repertoire	repertoire	NN
cord-004222-z4butywi	145	37	analysis	analysis	NN
cord-004222-z4butywi	145	38	with	with	IN
cord-004222-z4butywi	145	39	IGoR	IGoR	NNP
cord-004222-z4butywi	145	40	Estimating	estimate	VBG
cord-004222-z4butywi	145	41	the	the	DT
cord-004222-z4butywi	145	42	population	population	NN
cord-004222-z4butywi	145	43	size	size	NN
cord-004222-z4butywi	145	44	for	for	IN
cord-004222-z4butywi	145	45	capture	capture	NN
cord-004222-z4butywi	145	46	-	-	HYPH
cord-004222-z4butywi	145	47	recapture	recapture	NN
cord-004222-z4butywi	145	48	data	datum	NNS
cord-004222-z4butywi	145	49	with	with	IN
cord-004222-z4butywi	145	50	unequal	unequal	JJ
cord-004222-z4butywi	145	51	catchability	catchability	NN
cord-004222-z4butywi	145	52	How	how	WRB
cord-004222-z4butywi	145	53	many	many	JJ
cord-004222-z4butywi	145	54	different	different	JJ
cord-004222-z4butywi	145	55	clonotypes	clonotype	NNS
cord-004222-z4butywi	145	56	do	do	VBP
cord-004222-z4butywi	145	57	immune	immune	JJ
cord-004222-z4butywi	145	58	repertoires	repertoire	NNS
cord-004222-z4butywi	145	59	contain	contain	VBP
cord-004222-z4butywi	145	60	?	?	.
cord-004222-z4butywi	146	1	Robust	robust	JJ
cord-004222-z4butywi	146	2	estimates	estimate	NNS
cord-004222-z4butywi	146	3	of	of	IN
cord-004222-z4butywi	146	4	overall	overall	JJ
cord-004222-z4butywi	146	5	immune	immune	JJ
cord-004222-z4butywi	146	6	-	-	HYPH
cord-004222-z4butywi	146	7	repertoire	repertoire	NN
cord-004222-z4butywi	146	8	diversity	diversity	NN
cord-004222-z4butywi	146	9	from	from	IN
cord-004222-z4butywi	146	10	high	high	JJ
cord-004222-z4butywi	146	11	-	-	HYPH
cord-004222-z4butywi	146	12	throughput	throughput	NN
cord-004222-z4butywi	146	13	measurements	measurement	NNS
cord-004222-z4butywi	146	14	on	on	IN
cord-004222-z4butywi	146	15	samples	sample	NNS
cord-004222-z4butywi	146	16	Complete	complete	JJ
cord-004222-z4butywi	146	17	humanization	humanization	NN
cord-004222-z4butywi	146	18	of	of	IN
cord-004222-z4butywi	146	19	the	the	DT
cord-004222-z4butywi	146	20	mouse	mouse	NN
cord-004222-z4butywi	146	21	immunoglobulin	immunoglobulin	NN
cord-004222-z4butywi	146	22	loci	locus	NNS
cord-004222-z4butywi	146	23	enables	enable	VBZ
cord-004222-z4butywi	146	24	efficient	efficient	JJ
cord-004222-z4butywi	146	25	therapeutic	therapeutic	JJ
cord-004222-z4butywi	146	26	antibody	antibody	NN
cord-004222-z4butywi	146	27	discovery	discovery	NN
cord-004222-z4butywi	146	28	Mechanisms	Mechanisms	NNPS
cord-004222-z4butywi	146	29	that	that	WDT
cord-004222-z4butywi	146	30	shape	shape	VBP
cord-004222-z4butywi	146	31	human	human	JJ
cord-004222-z4butywi	146	32	antibody	antibody	NN
cord-004222-z4butywi	146	33	repertoire	repertoire	NN
cord-004222-z4butywi	146	34	development	development	NN
cord-004222-z4butywi	146	35	in	in	IN
cord-004222-z4butywi	146	36	mice	mouse	NNS
cord-004222-z4butywi	146	37	transgenic	transgenic	JJ
cord-004222-z4butywi	146	38	for	for	IN
cord-004222-z4butywi	146	39	human	human	JJ
cord-004222-z4butywi	146	40	ig	ig	NNP
cord-004222-z4butywi	146	41	H	H	NNP
cord-004222-z4butywi	146	42	and	and	CC
cord-004222-z4butywi	146	43	L	L	NNP
cord-004222-z4butywi	146	44	chain	chain	NN
cord-004222-z4butywi	146	45	loci	locus	NNS
cord-004222-z4butywi	146	46	Tissue	tissue	NN
cord-004222-z4butywi	146	47	-	-	HYPH
cord-004222-z4butywi	146	48	specific	specific	JJ
cord-004222-z4butywi	146	49	expressed	express	VBD
cord-004222-z4butywi	146	50	antibody	antibody	NN
cord-004222-z4butywi	146	51	variable	variable	JJ
cord-004222-z4butywi	146	52	gene	gene	NN
cord-004222-z4butywi	146	53	repertoires	repertoire	NNS
cord-004222-z4butywi	147	1	Intrinsic	intrinsic	JJ
cord-004222-z4butywi	147	2	bias	bias	NN
cord-004222-z4butywi	147	3	and	and	CC
cord-004222-z4butywi	147	4	public	public	JJ
cord-004222-z4butywi	147	5	rearrangements	rearrangement	NNS
cord-004222-z4butywi	147	6	in	in	IN
cord-004222-z4butywi	147	7	the	the	DT
cord-004222-z4butywi	147	8	human	human	JJ
cord-004222-z4butywi	147	9	immunoglobulin	immunoglobulin	NN
cord-004222-z4butywi	147	10	Vλ	Vλ	NNP
cord-004222-z4butywi	147	11	light	light	JJ
cord-004222-z4butywi	147	12	chain	chain	NN
cord-004222-z4butywi	147	13	repertoire	repertoire	NN
cord-004222-z4butywi	147	14	Immunoglobulin	immunoglobulin	NN
cord-004222-z4butywi	147	15	light	light	JJ
cord-004222-z4butywi	147	16	chain	chain	NN
cord-004222-z4butywi	147	17	gene	gene	NN
cord-004222-z4butywi	147	18	rearrangements	rearrangement	NNS
cord-004222-z4butywi	147	19	,	,	,
cord-004222-z4butywi	147	20	receptor	receptor	NN
cord-004222-z4butywi	147	21	editing	editing	NN
cord-004222-z4butywi	147	22	and	and	CC
cord-004222-z4butywi	147	23	the	the	DT
cord-004222-z4butywi	147	24	development	development	NN
cord-004222-z4butywi	147	25	of	of	IN
cord-004222-z4butywi	147	26	a	a	DT
cord-004222-z4butywi	147	27	Self	Self	NNP
cord-004222-z4butywi	147	28	-	-	HYPH
cord-004222-z4butywi	147	29	Tolerant	tolerant	JJ
cord-004222-z4butywi	147	30	antibody	antibody	NN
cord-004222-z4butywi	147	31	repertoire	repertoire	NN
cord-004222-z4butywi	148	1	Microbial	microbial	JJ
cord-004222-z4butywi	148	2	symbionts	symbiont	NNS
cord-004222-z4butywi	148	3	regulate	regulate	VBP
cord-004222-z4butywi	148	4	the	the	DT
cord-004222-z4butywi	148	5	primary	primary	JJ
cord-004222-z4butywi	148	6	ig	ig	NN
cord-004222-z4butywi	148	7	repertoire	repertoire	NN
cord-004222-z4butywi	148	8	B	B	NNP
cord-004222-z4butywi	148	9	cell	cell	NN
cord-004222-z4butywi	148	10	superantigens	superantigen	NNS
cord-004222-z4butywi	148	11	in	in	IN
cord-004222-z4butywi	148	12	the	the	DT
cord-004222-z4butywi	148	13	human	human	JJ
cord-004222-z4butywi	148	14	intestinal	intestinal	NN
cord-004222-z4butywi	148	15	microbiota	microbiota	NN
cord-004222-z4butywi	148	16	High	high	JJ
cord-004222-z4butywi	148	17	frequency	frequency	NN
cord-004222-z4butywi	148	18	of	of	IN
cord-004222-z4butywi	148	19	shared	share	VBN
cord-004222-z4butywi	148	20	clonotypes	clonotype	NNS
cord-004222-z4butywi	148	21	in	in	IN
cord-004222-z4butywi	148	22	human	human	JJ
cord-004222-z4butywi	148	23	B	b	NN
cord-004222-z4butywi	148	24	cell	cell	NN
cord-004222-z4butywi	148	25	receptor	receptor	NN
cord-004222-z4butywi	148	26	repertoires	repertoire	NNS
cord-004222-z4butywi	149	1	Moderated	moderate	VBN
cord-004222-z4butywi	149	2	estimation	estimation	NN
cord-004222-z4butywi	149	3	of	of	IN
cord-004222-z4butywi	149	4	fold	fold	JJ
cord-004222-z4butywi	149	5	change	change	NN
cord-004222-z4butywi	149	6	and	and	CC
cord-004222-z4butywi	149	7	dispersion	dispersion	NN
cord-004222-z4butywi	149	8	for	for	IN
cord-004222-z4butywi	149	9	RNA	RNA	NNP
cord-004222-z4butywi	149	10	-	-	HYPH
cord-004222-z4butywi	149	11	seq	seq	NN
cord-004222-z4butywi	149	12	data	datum	NNS
cord-004222-z4butywi	149	13	with	with	IN
cord-004222-z4butywi	149	14	DESeq	DESeq	NNP
cord-004222-z4butywi	149	15	.	.	.
cord-004222-z4butywi	150	1	2	2	LS
cord-004222-z4butywi	151	1	The	the	DT
cord-004222-z4butywi	151	2	authors	author	NNS
cord-004222-z4butywi	151	3	thank	thank	VBP
cord-004222-z4butywi	151	4	all	all	PDT
cord-004222-z4butywi	151	5	the	the	DT
cord-004222-z4butywi	151	6	study	study	NN
cord-004222-z4butywi	151	7	subjects	subject	NNS
cord-004222-z4butywi	151	8	for	for	IN
cord-004222-z4butywi	151	9	their	-PRON-	PRP$
cord-004222-z4butywi	151	10	participation	participation	NN
cord-004222-z4butywi	151	11	.	.	.
cord-004222-z4butywi	151	12	 	 	_SP
cord-004222-z4butywi	152	1	C.J.	C.J.	NNP
cord-004222-z4butywi	152	2	,	,	,
cord-004222-z4butywi	152	3	D.R.B.	D.R.B.	NNP
cord-004222-z4butywi	152	4	and	and	CC
cord-004222-z4butywi	152	5	B.B.	B.B.	NNP
cord-004222-z4butywi	152	6	planned	plan	VBD
cord-004222-z4butywi	152	7	and	and	CC
cord-004222-z4butywi	152	8	designed	design	VBD
cord-004222-z4butywi	152	9	the	the	DT
cord-004222-z4butywi	152	10	experiments	experiment	NNS
cord-004222-z4butywi	152	11	.	.	.
cord-004222-z4butywi	153	1	C.J.	C.J.	NNP
cord-004222-z4butywi	153	2	performed	perform	VBD
cord-004222-z4butywi	153	3	experiments	experiment	NNS
cord-004222-z4butywi	153	4	.	.	.
cord-004222-z4butywi	154	1	C.J.	C.J.	NNP
cord-004222-z4butywi	154	2	analyzed	analyze	VBD
cord-004222-z4butywi	154	3	data	datum	NNS
cord-004222-z4butywi	154	4	.	.	.
cord-004222-z4butywi	155	1	C.J.	C.J.	NNP
cord-004222-z4butywi	155	2	wrote	write	VBD
cord-004222-z4butywi	155	3	the	the	DT
cord-004222-z4butywi	155	4	manuscript	manuscript	NN
cord-004222-z4butywi	155	5	.	.	.
cord-004222-z4butywi	156	1	All	all	DT
cord-004222-z4butywi	156	2	authors	author	NNS
cord-004222-z4butywi	156	3	contributed	contribute	VBD
cord-004222-z4butywi	156	4	to	to	IN
cord-004222-z4butywi	156	5	manuscript	manuscript	NN
cord-004222-z4butywi	156	6	revisions	revision	NNS
cord-004222-z4butywi	156	7	.	.	.
cord-004222-z4butywi	157	1	The	the	DT
cord-004222-z4butywi	157	2	authors	author	NNS
cord-004222-z4butywi	157	3	declare	declare	VBP
cord-004222-z4butywi	157	4	no	no	DT
cord-004222-z4butywi	157	5	competing	compete	VBG
cord-004222-z4butywi	157	6	interests	interest	NNS
cord-004222-z4butywi	157	7	.	.	.
cord-004222-z4butywi	158	1	Supplementary	supplementary	JJ
cord-004222-z4butywi	158	2	information	information	NN
cord-004222-z4butywi	158	3	is	be	VBZ
cord-004222-z4butywi	158	4	available	available	JJ
cord-004222-z4butywi	158	5	for	for	IN
cord-004222-z4butywi	158	6	this	this	DT
cord-004222-z4butywi	158	7	paper	paper	NN
cord-004222-z4butywi	158	8	at	at	IN
cord-004222-z4butywi	158	9	https://doi.org/10.1038/s41598-020-57764-7.Correspondence	https://doi.org/10.1038/s41598-020-57764-7.correspondence	NN
cord-004222-z4butywi	158	10	and	and	CC
cord-004222-z4butywi	158	11	requests	request	NNS
cord-004222-z4butywi	158	12	for	for	IN
cord-004222-z4butywi	158	13	materials	material	NNS
cord-004222-z4butywi	158	14	should	should	MD
cord-004222-z4butywi	158	15	be	be	VB
cord-004222-z4butywi	158	16	addressed	address	VBN
cord-004222-z4butywi	158	17	to	to	IN
cord-004222-z4butywi	159	1	D.R.B.	D.R.B.	NNP
cord-004222-z4butywi	159	2	or	or	CC
cord-004222-z4butywi	159	3	B.B.Publisher	B.B.Publisher	NNP
cord-004222-z4butywi	159	4	's	's	POS
cord-004222-z4butywi	159	5	note	note	NN
cord-004222-z4butywi	159	6	Springer	Springer	NNP
cord-004222-z4butywi	159	7	Nature	Nature	NNP
cord-004222-z4butywi	159	8	remains	remain	VBZ
cord-004222-z4butywi	159	9	neutral	neutral	JJ
cord-004222-z4butywi	159	10	with	with	IN
cord-004222-z4butywi	159	11	regard	regard	NN
cord-004222-z4butywi	159	12	to	to	IN
cord-004222-z4butywi	159	13	jurisdictional	jurisdictional	JJ
cord-004222-z4butywi	159	14	claims	claim	NNS
cord-004222-z4butywi	159	15	in	in	IN
cord-004222-z4butywi	159	16	published	publish	VBN
cord-004222-z4butywi	159	17	maps	map	NNS
cord-004222-z4butywi	159	18	and	and	CC
cord-004222-z4butywi	159	19	institutional	institutional	JJ
cord-004222-z4butywi	159	20	affiliations	affiliation	NNS
cord-004222-z4butywi	159	21	.	.	.
cord-004222-z4butywi	160	1	Open	open	VB
cord-004222-z4butywi	160	2	Access	Access	NNP
cord-004222-z4butywi	161	1	This	this	DT
cord-004222-z4butywi	161	2	article	article	NN
cord-004222-z4butywi	161	3	is	be	VBZ
cord-004222-z4butywi	161	4	licensed	license	VBN
cord-004222-z4butywi	161	5	under	under	IN
cord-004222-z4butywi	161	6	a	a	DT
cord-004222-z4butywi	161	7	Creative	Creative	NNP
cord-004222-z4butywi	161	8	Commons	Commons	NNP
cord-004222-z4butywi	161	9	Attribution	Attribution	NNP
cord-004222-z4butywi	161	10	4.0	4.0	CD
cord-004222-z4butywi	161	11	International	International	NNP
cord-004222-z4butywi	161	12	License	License	NNP
cord-004222-z4butywi	161	13	,	,	,
cord-004222-z4butywi	161	14	which	which	WDT
cord-004222-z4butywi	161	15	permits	permit	VBZ
cord-004222-z4butywi	161	16	use	use	NN
cord-004222-z4butywi	161	17	,	,	,
cord-004222-z4butywi	161	18	sharing	sharing	NN
cord-004222-z4butywi	161	19	,	,	,
cord-004222-z4butywi	161	20	adaptation	adaptation	NN
cord-004222-z4butywi	161	21	,	,	,
cord-004222-z4butywi	161	22	distribution	distribution	NN
cord-004222-z4butywi	161	23	and	and	CC
cord-004222-z4butywi	161	24	reproduction	reproduction	NN
cord-004222-z4butywi	161	25	in	in	IN
cord-004222-z4butywi	161	26	any	any	DT
cord-004222-z4butywi	161	27	medium	medium	NN
cord-004222-z4butywi	161	28	or	or	CC
cord-004222-z4butywi	161	29	format	format	NN
cord-004222-z4butywi	161	30	,	,	,
cord-004222-z4butywi	161	31	as	as	RB
cord-004222-z4butywi	161	32	long	long	RB
cord-004222-z4butywi	161	33	as	as	IN
cord-004222-z4butywi	161	34	you	-PRON-	PRP
cord-004222-z4butywi	161	35	give	give	VBP
cord-004222-z4butywi	161	36	appropriate	appropriate	JJ
cord-004222-z4butywi	161	37	credit	credit	NN
cord-004222-z4butywi	161	38	to	to	IN
cord-004222-z4butywi	161	39	the	the	DT
cord-004222-z4butywi	161	40	original	original	JJ
cord-004222-z4butywi	161	41	author(s	author(s	NNP
cord-004222-z4butywi	161	42	)	)	-RRB-
cord-004222-z4butywi	161	43	and	and	CC
cord-004222-z4butywi	161	44	the	the	DT
cord-004222-z4butywi	161	45	source	source	NN
cord-004222-z4butywi	161	46	,	,	,
cord-004222-z4butywi	161	47	provide	provide	VB
cord-004222-z4butywi	161	48	a	a	DT
cord-004222-z4butywi	161	49	link	link	NN
cord-004222-z4butywi	161	50	to	to	IN
cord-004222-z4butywi	161	51	the	the	DT
cord-004222-z4butywi	161	52	Creative	Creative	NNP
cord-004222-z4butywi	161	53	Commons	Commons	NNP
cord-004222-z4butywi	161	54	license	license	NN
cord-004222-z4butywi	161	55	,	,	,
cord-004222-z4butywi	161	56	and	and	CC
cord-004222-z4butywi	161	57	indicate	indicate	VBP
cord-004222-z4butywi	161	58	if	if	IN
cord-004222-z4butywi	161	59	changes	change	NNS
cord-004222-z4butywi	161	60	were	be	VBD
cord-004222-z4butywi	161	61	made	make	VBN
cord-004222-z4butywi	161	62	.	.	.
cord-004222-z4butywi	162	1	The	the	DT
cord-004222-z4butywi	162	2	images	image	NNS
cord-004222-z4butywi	162	3	or	or	CC
cord-004222-z4butywi	162	4	other	other	JJ
cord-004222-z4butywi	162	5	third	third	JJ
cord-004222-z4butywi	162	6	party	party	NN
cord-004222-z4butywi	162	7	material	material	NN
cord-004222-z4butywi	162	8	in	in	IN
cord-004222-z4butywi	162	9	this	this	DT
cord-004222-z4butywi	162	10	article	article	NN
cord-004222-z4butywi	162	11	are	be	VBP
cord-004222-z4butywi	162	12	included	include	VBN
cord-004222-z4butywi	162	13	in	in	IN
cord-004222-z4butywi	162	14	the	the	DT
cord-004222-z4butywi	162	15	article	article	NN
cord-004222-z4butywi	162	16	's	's	POS
cord-004222-z4butywi	162	17	Creative	Creative	NNP
cord-004222-z4butywi	162	18	Commons	Commons	NNP
cord-004222-z4butywi	162	19	license	license	NN
cord-004222-z4butywi	162	20	,	,	,
cord-004222-z4butywi	162	21	unless	unless	IN
cord-004222-z4butywi	162	22	indicated	indicate	VBN
cord-004222-z4butywi	162	23	otherwise	otherwise	RB
cord-004222-z4butywi	162	24	in	in	IN
cord-004222-z4butywi	162	25	a	a	DT
cord-004222-z4butywi	162	26	credit	credit	NN
cord-004222-z4butywi	162	27	line	line	NN
cord-004222-z4butywi	162	28	to	to	IN
cord-004222-z4butywi	162	29	the	the	DT
cord-004222-z4butywi	162	30	material	material	NN
cord-004222-z4butywi	162	31	.	.	.
cord-004222-z4butywi	163	1	If	if	IN
cord-004222-z4butywi	163	2	material	material	NN
cord-004222-z4butywi	163	3	is	be	VBZ
cord-004222-z4butywi	163	4	not	not	RB
cord-004222-z4butywi	163	5	included	include	VBN
cord-004222-z4butywi	163	6	in	in	IN
cord-004222-z4butywi	163	7	the	the	DT
cord-004222-z4butywi	163	8	article	article	NN
cord-004222-z4butywi	163	9	's	's	POS
cord-004222-z4butywi	163	10	Creative	Creative	NNP
cord-004222-z4butywi	163	11	Commons	Commons	NNP
cord-004222-z4butywi	163	12	license	license	NN
cord-004222-z4butywi	163	13	and	and	CC
cord-004222-z4butywi	163	14	your	-PRON-	PRP$
cord-004222-z4butywi	163	15	intended	intend	VBN
cord-004222-z4butywi	163	16	use	use	NN
cord-004222-z4butywi	163	17	is	be	VBZ
cord-004222-z4butywi	163	18	not	not	RB
cord-004222-z4butywi	163	19	permitted	permit	VBN
cord-004222-z4butywi	163	20	by	by	IN
cord-004222-z4butywi	163	21	statutory	statutory	JJ
cord-004222-z4butywi	163	22	regulation	regulation	NN
cord-004222-z4butywi	163	23	or	or	CC
cord-004222-z4butywi	163	24	exceeds	exceed	VBZ
cord-004222-z4butywi	163	25	the	the	DT
cord-004222-z4butywi	163	26	permitted	permit	VBN
cord-004222-z4butywi	163	27	use	use	NN
cord-004222-z4butywi	163	28	,	,	,
cord-004222-z4butywi	163	29	you	-PRON-	PRP
cord-004222-z4butywi	163	30	will	will	MD
cord-004222-z4butywi	163	31	need	need	VB
cord-004222-z4butywi	163	32	to	to	TO
cord-004222-z4butywi	163	33	obtain	obtain	VB
cord-004222-z4butywi	163	34	permission	permission	NN
cord-004222-z4butywi	163	35	directly	directly	RB
cord-004222-z4butywi	163	36	from	from	IN
cord-004222-z4butywi	163	37	the	the	DT
cord-004222-z4butywi	163	38	copyright	copyright	NN
cord-004222-z4butywi	163	39	holder	holder	NN
cord-004222-z4butywi	163	40	.	.	.
cord-004222-z4butywi	164	1	To	to	TO
cord-004222-z4butywi	164	2	view	view	VB
cord-004222-z4butywi	164	3	a	a	DT
cord-004222-z4butywi	164	4	copy	copy	NN
cord-004222-z4butywi	164	5	of	of	IN
cord-004222-z4butywi	164	6	this	this	DT
cord-004222-z4butywi	164	7	license	license	NN
cord-004222-z4butywi	164	8	,	,	,
cord-004222-z4butywi	164	9	visit	visit	VB
cord-004222-z4butywi	164	10	http://creativecommons.org/licenses/by/4.0/.	http://creativecommons.org/licenses/by/4.0/.	NNP