id author title date pages extension mime words sentences flesch summary cache txt cord-317579-ige2h4pd Nie, Lei Nanostructured selenium-doped biphasic calcium phosphate with in situ incorporation of silver for antibacterial applications 2020-08-13 .txt text/plain 6082 354 47 The results confirmed that the SeO(3)(2−) was doped at the PO(4)(3−) position and silver nanoparticles were deposited on the surface of SeB-NPs. Next, Transmission Electron Microscopy (TEM) analysis displayed that the prepared (Ag)SeB-NPs had a needle-cluster-like morphology. At the same time, biphasic calcium phosphate nanoparticles (BCP-NPs) and selenium-doped hydroxyapatite nanoparticles (SeHA-NPs) were prepared for comparison (Electronic Supplementary Material). Compared with the control group, the doping selenium into BCP-NPs had slight influence on the antibacterial activity, and it had a slight inhibitory effect against bacteria of SeB-NPs after 12 h of culture. The stated objective of this study was to synthesis new-style biphasic calcium phosphate nanoparticles (BCP-NPs) with excellent cytocompatibility and antibacterial activity for further hard-tissue engineering applications. After the deposition of silver, cells cultured with all Ag SeB-NPs samples had similar proliferation profiles compared with SeB-NPs. Not only can the addition of selenium and silver improve the growth of the cells with BCP-NPs, but the antibacterial activity was acquired, which has potential for infection-resistant replacement materials 61, 62 . ./cache/cord-317579-ige2h4pd.txt ./txt/cord-317579-ige2h4pd.txt