id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-002290-wvo22jx2	Liu, Cheng	Association of Mannose-binding Lectin Polymorphisms with Tuberculosis Susceptibility among Chinese	2016-11-04		.txt	text/plain	3772	201	48	In this study four functional single-nucleotide polymorphisms (SNPs, H/L, X/Y, P/Q and A/B) across the MBL2 gene were genotyped by direct DNA sequencing of PCR products in a case-control population of Chinese Han origin, consisting of 1,020 patients with pulmonary TB and 1,020 controls. In 1,020 controls, this distribution was 723 (70.9%), 234 (22.9%) and 63 (6.2%), respectively (OR = 1.56, 95% CI 1.29-1.90, P = 1.4 × 10 −6 , with adjustment for age and gender; simulation number = 10,000,000; Table 2 ), implicating that the individuals bearing medium or low expression haplotype pairs had an increased risk of TB and that the MBL deficiency might play a potential role in susceptibility to TB. In this study, we investigated all of the four functional SNPs in the MBL2 gene, individually or in haplotype or haplotype pairs, in a large case-control population of Chinese Han origin, totally consisting of 1,020 patients with TB and 1,020 controls.	./cache/cord-002290-wvo22jx2.txt	./txt/cord-002290-wvo22jx2.txt