id	sid	tid	token	lemma	pos
cord-002180-gsdk5x3e	1	1	key	key	JJ
cord-002180-gsdk5x3e	1	2	:	:	:
cord-002180-gsdk5x3e	1	3	cord-002180-gsdk5x3e	cord-002180-gsdk5x3e	CD
cord-002180-gsdk5x3e	1	4	authors	author	NNS
cord-002180-gsdk5x3e	1	5	:	:	:
cord-002180-gsdk5x3e	1	6	Davies	Davies	NNP
cord-002180-gsdk5x3e	1	7	,	,	,
cord-002180-gsdk5x3e	1	8	Colin	Colin	NNP
cord-002180-gsdk5x3e	1	9	;	;	:
cord-002180-gsdk5x3e	1	10	Ward	Ward	NNP
cord-002180-gsdk5x3e	1	11	,	,	,
cord-002180-gsdk5x3e	1	12	Vernon	Vernon	NNP
cord-002180-gsdk5x3e	1	13	K.	K.	NNP
cord-002180-gsdk5x3e	1	14	title	title	NN
cord-002180-gsdk5x3e	1	15	:	:	:
cord-002180-gsdk5x3e	1	16	Expression	expression	NN
cord-002180-gsdk5x3e	1	17	of	of	IN
cord-002180-gsdk5x3e	1	18	the	the	DT
cord-002180-gsdk5x3e	1	19	NS5	ns5	JJ
cord-002180-gsdk5x3e	1	20	(	(	-LRB-
cord-002180-gsdk5x3e	1	21	VPg	VPg	NNS
cord-002180-gsdk5x3e	1	22	)	)	-RRB-
cord-002180-gsdk5x3e	1	23	Protein	Protein	NNP
cord-002180-gsdk5x3e	1	24	of	of	IN
cord-002180-gsdk5x3e	1	25	Murine	Murine	NNP
cord-002180-gsdk5x3e	1	26	Norovirus	Norovirus	NNP
cord-002180-gsdk5x3e	1	27	Induces	induce	VBZ
cord-002180-gsdk5x3e	1	28	a	a	DT
cord-002180-gsdk5x3e	1	29	G1	G1	NNP
cord-002180-gsdk5x3e	1	30	/	/	SYM
cord-002180-gsdk5x3e	1	31	S	S	NNP
cord-002180-gsdk5x3e	1	32	Phase	Phase	NNP
cord-002180-gsdk5x3e	1	33	Arrest	Arrest	NNP
cord-002180-gsdk5x3e	1	34	date	date	NN
cord-002180-gsdk5x3e	1	35	:	:	:
cord-002180-gsdk5x3e	1	36	2016	2016	CD
cord-002180-gsdk5x3e	1	37	-	-	HYPH
cord-002180-gsdk5x3e	1	38	08	08	CD
cord-002180-gsdk5x3e	1	39	-	-	HYPH
cord-002180-gsdk5x3e	1	40	24	24	CD
cord-002180-gsdk5x3e	1	41	journal	journal	NN
cord-002180-gsdk5x3e	1	42	:	:	:
cord-002180-gsdk5x3e	2	1	PLoS	PLoS	NNP
cord-002180-gsdk5x3e	2	2	One	one	CD
cord-002180-gsdk5x3e	2	3	DOI	DOI	NNP
cord-002180-gsdk5x3e	2	4	:	:	:
cord-002180-gsdk5x3e	2	5	10.1371/	10.1371/	CD
cord-002180-gsdk5x3e	3	1	journal.pone.0161582	journal.pone.0161582	NNP
cord-002180-gsdk5x3e	3	2	sha	sha	NNP
cord-002180-gsdk5x3e	3	3	:	:	:
cord-002180-gsdk5x3e	4	1	7b9a303570b221251e6281e20f70ecaa125c4e78	7b9a303570b221251e6281e20f70ecaa125c4e78	CD
cord-002180-gsdk5x3e	4	2	doc_id	doc_id	CD
cord-002180-gsdk5x3e	4	3	:	:	:
cord-002180-gsdk5x3e	4	4	2180	2180	CD
cord-002180-gsdk5x3e	4	5	cord_uid	cord_uid	FW
cord-002180-gsdk5x3e	4	6	:	:	:
cord-002180-gsdk5x3e	5	1	gsdk5x3e	gsdk5x3e	JJ
cord-002180-gsdk5x3e	5	2	Murine	Murine	NNP
cord-002180-gsdk5x3e	5	3	norovirus-1	norovirus-1	NNP
cord-002180-gsdk5x3e	5	4	(	(	-LRB-
cord-002180-gsdk5x3e	5	5	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	5	6	)	)	-RRB-
cord-002180-gsdk5x3e	5	7	is	be	VBZ
cord-002180-gsdk5x3e	5	8	known	know	VBN
cord-002180-gsdk5x3e	5	9	to	to	TO
cord-002180-gsdk5x3e	5	10	subvert	subvert	VB
cord-002180-gsdk5x3e	5	11	host	host	NN
cord-002180-gsdk5x3e	5	12	cell	cell	NN
cord-002180-gsdk5x3e	5	13	division	division	NN
cord-002180-gsdk5x3e	5	14	inducing	induce	VBG
cord-002180-gsdk5x3e	5	15	an	an	DT
cord-002180-gsdk5x3e	5	16	accumulation	accumulation	NN
cord-002180-gsdk5x3e	5	17	of	of	IN
cord-002180-gsdk5x3e	5	18	cells	cell	NNS
cord-002180-gsdk5x3e	5	19	in	in	IN
cord-002180-gsdk5x3e	5	20	the	the	DT
cord-002180-gsdk5x3e	5	21	G(0)/G(1	G(0)/G(1	NNP
cord-002180-gsdk5x3e	5	22	)	)	-RRB-
cord-002180-gsdk5x3e	5	23	phase	phase	NN
cord-002180-gsdk5x3e	5	24	,	,	,
cord-002180-gsdk5x3e	5	25	creating	create	VBG
cord-002180-gsdk5x3e	5	26	conditions	condition	NNS
cord-002180-gsdk5x3e	5	27	where	where	WRB
cord-002180-gsdk5x3e	5	28	viral	viral	JJ
cord-002180-gsdk5x3e	5	29	replication	replication	NN
cord-002180-gsdk5x3e	5	30	is	be	VBZ
cord-002180-gsdk5x3e	5	31	favored	favor	VBN
cord-002180-gsdk5x3e	5	32	.	.	.
cord-002180-gsdk5x3e	6	1	This	this	DT
cord-002180-gsdk5x3e	6	2	study	study	NN
cord-002180-gsdk5x3e	6	3	identified	identify	VBD
cord-002180-gsdk5x3e	6	4	that	that	IN
cord-002180-gsdk5x3e	6	5	NS5	ns5	JJ
cord-002180-gsdk5x3e	6	6	(	(	-LRB-
cord-002180-gsdk5x3e	6	7	VPg	VPg	NNS
cord-002180-gsdk5x3e	6	8	)	)	-RRB-
cord-002180-gsdk5x3e	6	9	,	,	,
cord-002180-gsdk5x3e	6	10	is	be	VBZ
cord-002180-gsdk5x3e	6	11	capable	capable	JJ
cord-002180-gsdk5x3e	6	12	of	of	IN
cord-002180-gsdk5x3e	6	13	inducing	induce	VBG
cord-002180-gsdk5x3e	6	14	cell	cell	NN
cord-002180-gsdk5x3e	6	15	cycle	cycle	NN
cord-002180-gsdk5x3e	6	16	arrest	arrest	NN
cord-002180-gsdk5x3e	6	17	in	in	IN
cord-002180-gsdk5x3e	6	18	the	the	DT
cord-002180-gsdk5x3e	6	19	absence	absence	NN
cord-002180-gsdk5x3e	6	20	of	of	IN
cord-002180-gsdk5x3e	6	21	viral	viral	JJ
cord-002180-gsdk5x3e	6	22	replication	replication	NN
cord-002180-gsdk5x3e	6	23	or	or	CC
cord-002180-gsdk5x3e	6	24	other	other	JJ
cord-002180-gsdk5x3e	6	25	viral	viral	JJ
cord-002180-gsdk5x3e	6	26	proteins	protein	NNS
cord-002180-gsdk5x3e	6	27	in	in	IN
cord-002180-gsdk5x3e	6	28	an	an	DT
cord-002180-gsdk5x3e	6	29	analogous	analogous	JJ
cord-002180-gsdk5x3e	6	30	manner	manner	NN
cord-002180-gsdk5x3e	6	31	to	to	IN
cord-002180-gsdk5x3e	6	32	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	6	33	infection	infection	NN
cord-002180-gsdk5x3e	6	34	.	.	.
cord-002180-gsdk5x3e	7	1	NS5	ns5	JJ
cord-002180-gsdk5x3e	7	2	expression	expression	NN
cord-002180-gsdk5x3e	7	3	induced	induce	VBD
cord-002180-gsdk5x3e	7	4	an	an	DT
cord-002180-gsdk5x3e	7	5	accumulation	accumulation	NN
cord-002180-gsdk5x3e	7	6	of	of	IN
cord-002180-gsdk5x3e	7	7	cells	cell	NNS
cord-002180-gsdk5x3e	7	8	in	in	IN
cord-002180-gsdk5x3e	7	9	the	the	DT
cord-002180-gsdk5x3e	7	10	G(0)/G(1	G(0)/G(1	NNP
cord-002180-gsdk5x3e	7	11	)	)	-RRB-
cord-002180-gsdk5x3e	7	12	phase	phase	NN
cord-002180-gsdk5x3e	7	13	in	in	IN
cord-002180-gsdk5x3e	7	14	an	an	DT
cord-002180-gsdk5x3e	7	15	asynchronous	asynchronous	JJ
cord-002180-gsdk5x3e	7	16	population	population	NN
cord-002180-gsdk5x3e	7	17	by	by	IN
cord-002180-gsdk5x3e	7	18	inhibiting	inhibit	VBG
cord-002180-gsdk5x3e	7	19	progression	progression	NN
cord-002180-gsdk5x3e	7	20	at	at	IN
cord-002180-gsdk5x3e	7	21	the	the	DT
cord-002180-gsdk5x3e	7	22	G(1)/S	G(1)/S	NNP
cord-002180-gsdk5x3e	7	23	restriction	restriction	NN
cord-002180-gsdk5x3e	7	24	point	point	NN
cord-002180-gsdk5x3e	7	25	.	.	.
cord-002180-gsdk5x3e	8	1	Furthermore	furthermore	RB
cord-002180-gsdk5x3e	8	2	,	,	,
cord-002180-gsdk5x3e	8	3	NS5	ns5	JJ
cord-002180-gsdk5x3e	8	4	expression	expression	NN
cord-002180-gsdk5x3e	8	5	resulted	result	VBD
cord-002180-gsdk5x3e	8	6	in	in	IN
cord-002180-gsdk5x3e	8	7	a	a	DT
cord-002180-gsdk5x3e	8	8	down	down	JJ
cord-002180-gsdk5x3e	8	9	-	-	HYPH
cord-002180-gsdk5x3e	8	10	regulation	regulation	NN
cord-002180-gsdk5x3e	8	11	of	of	IN
cord-002180-gsdk5x3e	8	12	cyclin	cyclin	NN
cord-002180-gsdk5x3e	8	13	A	a	DT
cord-002180-gsdk5x3e	8	14	expression	expression	NN
cord-002180-gsdk5x3e	8	15	in	in	IN
cord-002180-gsdk5x3e	8	16	asynchronous	asynchronous	JJ
cord-002180-gsdk5x3e	8	17	cells	cell	NNS
cord-002180-gsdk5x3e	8	18	and	and	CC
cord-002180-gsdk5x3e	8	19	inhibited	inhibited	JJ
cord-002180-gsdk5x3e	8	20	cyclin	cyclin	NN
cord-002180-gsdk5x3e	8	21	A	a	DT
cord-002180-gsdk5x3e	8	22	expression	expression	NN
cord-002180-gsdk5x3e	8	23	in	in	IN
cord-002180-gsdk5x3e	8	24	cells	cell	NNS
cord-002180-gsdk5x3e	8	25	progressing	progress	VBG
cord-002180-gsdk5x3e	8	26	from	from	IN
cord-002180-gsdk5x3e	8	27	G(1	G(1	NNP
cord-002180-gsdk5x3e	8	28	)	)	-RRB-
cord-002180-gsdk5x3e	8	29	to	to	IN
cord-002180-gsdk5x3e	8	30	S	s	NN
cord-002180-gsdk5x3e	8	31	phase	phase	NN
cord-002180-gsdk5x3e	8	32	.	.	.
cord-002180-gsdk5x3e	9	1	The	the	DT
cord-002180-gsdk5x3e	9	2	activity	activity	NN
cord-002180-gsdk5x3e	9	3	of	of	IN
cord-002180-gsdk5x3e	9	4	NS5	ns5	JJ
cord-002180-gsdk5x3e	9	5	on	on	IN
cord-002180-gsdk5x3e	9	6	the	the	DT
cord-002180-gsdk5x3e	9	7	host	host	NN
cord-002180-gsdk5x3e	9	8	cell	cell	NN
cord-002180-gsdk5x3e	9	9	cycle	cycle	NN
cord-002180-gsdk5x3e	9	10	occurs	occur	VBZ
cord-002180-gsdk5x3e	9	11	through	through	IN
cord-002180-gsdk5x3e	9	12	an	an	DT
cord-002180-gsdk5x3e	9	13	uncharacterized	uncharacterized	JJ
cord-002180-gsdk5x3e	9	14	function	function	NN
cord-002180-gsdk5x3e	9	15	.	.	.
cord-002180-gsdk5x3e	10	1	Amino	amino	NN
cord-002180-gsdk5x3e	10	2	acid	acid	NN
cord-002180-gsdk5x3e	10	3	substitutions	substitution	NNS
cord-002180-gsdk5x3e	10	4	of	of	IN
cord-002180-gsdk5x3e	10	5	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	10	6	)	)	-RRB-
cord-002180-gsdk5x3e	10	7	and	and	CC
cord-002180-gsdk5x3e	10	8	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	10	9	)	)	-RRB-
cord-002180-gsdk5x3e	11	1	that	that	WDT
cord-002180-gsdk5x3e	11	2	inhibit	inhibit	VBP
cord-002180-gsdk5x3e	11	3	the	the	DT
cord-002180-gsdk5x3e	11	4	ability	ability	NN
cord-002180-gsdk5x3e	11	5	for	for	IN
cord-002180-gsdk5x3e	11	6	NS5	NS5	NNP
cord-002180-gsdk5x3e	11	7	to	to	TO
cord-002180-gsdk5x3e	11	8	attach	attach	VB
cord-002180-gsdk5x3e	11	9	to	to	IN
cord-002180-gsdk5x3e	11	10	RNA	RNA	NNP
cord-002180-gsdk5x3e	11	11	and	and	CC
cord-002180-gsdk5x3e	11	12	recruit	recruit	VB
cord-002180-gsdk5x3e	11	13	host	host	NN
cord-002180-gsdk5x3e	11	14	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	11	15	translation	translation	NN
cord-002180-gsdk5x3e	11	16	initiation	initiation	NN
cord-002180-gsdk5x3e	11	17	factors	factor	NNS
cord-002180-gsdk5x3e	11	18	,	,	,
cord-002180-gsdk5x3e	11	19	respectively	respectively	RB
cord-002180-gsdk5x3e	11	20	,	,	,
cord-002180-gsdk5x3e	11	21	retained	retain	VBD
cord-002180-gsdk5x3e	11	22	the	the	DT
cord-002180-gsdk5x3e	11	23	ability	ability	NN
cord-002180-gsdk5x3e	11	24	to	to	TO
cord-002180-gsdk5x3e	11	25	induce	induce	VB
cord-002180-gsdk5x3e	11	26	an	an	DT
cord-002180-gsdk5x3e	11	27	accumulation	accumulation	NN
cord-002180-gsdk5x3e	11	28	of	of	IN
cord-002180-gsdk5x3e	11	29	cells	cell	NNS
cord-002180-gsdk5x3e	11	30	in	in	IN
cord-002180-gsdk5x3e	11	31	the	the	DT
cord-002180-gsdk5x3e	11	32	G(0)/G(1	G(0)/G(1	NNP
cord-002180-gsdk5x3e	11	33	)	)	-RRB-
cord-002180-gsdk5x3e	11	34	phase	phase	NN
cord-002180-gsdk5x3e	11	35	as	as	IN
cord-002180-gsdk5x3e	11	36	identified	identify	VBN
cord-002180-gsdk5x3e	11	37	for	for	IN
cord-002180-gsdk5x3e	11	38	wild	wild	JJ
cord-002180-gsdk5x3e	11	39	-	-	HYPH
cord-002180-gsdk5x3e	11	40	type	type	NN
cord-002180-gsdk5x3e	11	41	NS5	ns5	NN
cord-002180-gsdk5x3e	11	42	.	.	.
cord-002180-gsdk5x3e	12	1	To	to	IN
cord-002180-gsdk5x3e	12	2	the	the	DT
cord-002180-gsdk5x3e	12	3	best	good	JJS
cord-002180-gsdk5x3e	12	4	of	of	IN
cord-002180-gsdk5x3e	12	5	our	-PRON-	PRP$
cord-002180-gsdk5x3e	12	6	knowledge	knowledge	NN
cord-002180-gsdk5x3e	12	7	,	,	,
cord-002180-gsdk5x3e	12	8	this	this	DT
cord-002180-gsdk5x3e	12	9	is	be	VBZ
cord-002180-gsdk5x3e	12	10	the	the	DT
cord-002180-gsdk5x3e	12	11	first	first	JJ
cord-002180-gsdk5x3e	12	12	report	report	NN
cord-002180-gsdk5x3e	12	13	of	of	IN
cord-002180-gsdk5x3e	12	14	a	a	DT
cord-002180-gsdk5x3e	12	15	VPg	vpg	NN
cord-002180-gsdk5x3e	12	16	protein	protein	NN
cord-002180-gsdk5x3e	12	17	manipulating	manipulate	VBG
cord-002180-gsdk5x3e	12	18	the	the	DT
cord-002180-gsdk5x3e	12	19	host	host	NN
cord-002180-gsdk5x3e	12	20	cell	cell	NN
cord-002180-gsdk5x3e	12	21	cycle	cycle	NN
cord-002180-gsdk5x3e	12	22	.	.	.
cord-002180-gsdk5x3e	13	1	Noroviruses	noroviruse	NNS
cord-002180-gsdk5x3e	13	2	are	be	VBP
cord-002180-gsdk5x3e	13	3	non	non	JJ
cord-002180-gsdk5x3e	13	4	-	-	JJ
cord-002180-gsdk5x3e	13	5	enveloped	enveloped	JJ
cord-002180-gsdk5x3e	13	6	viruses	virus	NNS
cord-002180-gsdk5x3e	13	7	from	from	IN
cord-002180-gsdk5x3e	13	8	the	the	DT
cord-002180-gsdk5x3e	13	9	Caliciviridae	Caliciviridae	NNP
cord-002180-gsdk5x3e	13	10	family	family	NN
cord-002180-gsdk5x3e	13	11	that	that	WDT
cord-002180-gsdk5x3e	13	12	cause	cause	VBP
cord-002180-gsdk5x3e	13	13	gastroenteritis	gastroenteritis	NN
cord-002180-gsdk5x3e	13	14	in	in	IN
cord-002180-gsdk5x3e	13	15	a	a	DT
cord-002180-gsdk5x3e	13	16	variety	variety	NN
cord-002180-gsdk5x3e	13	17	of	of	IN
cord-002180-gsdk5x3e	13	18	mammals	mammal	NNS
cord-002180-gsdk5x3e	13	19	including	include	VBG
cord-002180-gsdk5x3e	13	20	humans	human	NNS
cord-002180-gsdk5x3e	13	21	[	[	-LRB-
cord-002180-gsdk5x3e	13	22	1	1	CD
cord-002180-gsdk5x3e	13	23	]	]	-RRB-
cord-002180-gsdk5x3e	13	24	[	[	-LRB-
cord-002180-gsdk5x3e	13	25	2	2	CD
cord-002180-gsdk5x3e	13	26	]	]	-RRB-
cord-002180-gsdk5x3e	13	27	[	[	-LRB-
cord-002180-gsdk5x3e	13	28	3	3	CD
cord-002180-gsdk5x3e	13	29	]	]	-RRB-
cord-002180-gsdk5x3e	13	30	[	[	-LRB-
cord-002180-gsdk5x3e	13	31	4	4	CD
cord-002180-gsdk5x3e	13	32	]	]	-RRB-
cord-002180-gsdk5x3e	13	33	[	[	-LRB-
cord-002180-gsdk5x3e	13	34	5	5	CD
cord-002180-gsdk5x3e	13	35	]	]	-RRB-
cord-002180-gsdk5x3e	13	36	.	.	.
cord-002180-gsdk5x3e	14	1	Human	human	JJ
cord-002180-gsdk5x3e	14	2	norovirus	norovirus	NN
cord-002180-gsdk5x3e	14	3	(	(	-LRB-
cord-002180-gsdk5x3e	14	4	HuNoV	HuNoV	NNP
cord-002180-gsdk5x3e	14	5	)	)	-RRB-
cord-002180-gsdk5x3e	14	6	infections	infection	NNS
cord-002180-gsdk5x3e	14	7	account	account	VBP
cord-002180-gsdk5x3e	14	8	for	for	IN
cord-002180-gsdk5x3e	14	9	significant	significant	JJ
cord-002180-gsdk5x3e	14	10	mortality	mortality	NN
cord-002180-gsdk5x3e	14	11	in	in	IN
cord-002180-gsdk5x3e	14	12	the	the	DT
cord-002180-gsdk5x3e	14	13	developing	develop	VBG
cord-002180-gsdk5x3e	14	14	world	world	NN
cord-002180-gsdk5x3e	14	15	,	,	,
cord-002180-gsdk5x3e	14	16	and	and	CC
cord-002180-gsdk5x3e	14	17	in	in	IN
cord-002180-gsdk5x3e	14	18	the	the	DT
cord-002180-gsdk5x3e	14	19	developed	develop	VBN
cord-002180-gsdk5x3e	14	20	world	world	NN
cord-002180-gsdk5x3e	14	21	norovirus	norovirus	NN
cord-002180-gsdk5x3e	14	22	outbreaks	outbreak	NNS
cord-002180-gsdk5x3e	14	23	come	come	VBP
cord-002180-gsdk5x3e	14	24	with	with	IN
cord-002180-gsdk5x3e	14	25	a	a	DT
cord-002180-gsdk5x3e	14	26	substantial	substantial	JJ
cord-002180-gsdk5x3e	14	27	financial	financial	JJ
cord-002180-gsdk5x3e	14	28	burden	burden	NN
cord-002180-gsdk5x3e	14	29	[	[	-LRB-
cord-002180-gsdk5x3e	14	30	6	6	CD
cord-002180-gsdk5x3e	14	31	]	]	-RRB-
cord-002180-gsdk5x3e	14	32	.	.	.
cord-002180-gsdk5x3e	15	1	HuNoV	HuNoV	NNP
cord-002180-gsdk5x3e	15	2	research	research	NN
cord-002180-gsdk5x3e	15	3	has	have	VBZ
cord-002180-gsdk5x3e	15	4	been	be	VBN
cord-002180-gsdk5x3e	15	5	hampered	hamper	VBN
cord-002180-gsdk5x3e	15	6	by	by	IN
cord-002180-gsdk5x3e	15	7	the	the	DT
cord-002180-gsdk5x3e	15	8	lack	lack	NN
cord-002180-gsdk5x3e	15	9	of	of	IN
cord-002180-gsdk5x3e	15	10	a	a	DT
cord-002180-gsdk5x3e	15	11	reproducible	reproducible	JJ
cord-002180-gsdk5x3e	15	12	animal	animal	NN
cord-002180-gsdk5x3e	15	13	or	or	CC
cord-002180-gsdk5x3e	15	14	cell	cell	NN
cord-002180-gsdk5x3e	15	15	culture	culture	NN
cord-002180-gsdk5x3e	15	16	system	system	NN
cord-002180-gsdk5x3e	15	17	that	that	WDT
cord-002180-gsdk5x3e	15	18	supports	support	VBZ
cord-002180-gsdk5x3e	15	19	viral	viral	JJ
cord-002180-gsdk5x3e	15	20	replication	replication	NN
cord-002180-gsdk5x3e	15	21	.	.	.
cord-002180-gsdk5x3e	16	1	Using	use	VBG
cord-002180-gsdk5x3e	16	2	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	16	3	as	as	IN
cord-002180-gsdk5x3e	16	4	a	a	DT
cord-002180-gsdk5x3e	16	5	model	model	NN
cord-002180-gsdk5x3e	16	6	allows	allow	VBZ
cord-002180-gsdk5x3e	16	7	norovirus	norovirus	NN
cord-002180-gsdk5x3e	16	8	replication	replication	NN
cord-002180-gsdk5x3e	16	9	and	and	CC
cord-002180-gsdk5x3e	16	10	host	host	NN
cord-002180-gsdk5x3e	16	11	cell	cell	NN
cord-002180-gsdk5x3e	16	12	interactions	interaction	NNS
cord-002180-gsdk5x3e	16	13	to	to	TO
cord-002180-gsdk5x3e	16	14	be	be	VB
cord-002180-gsdk5x3e	16	15	studied	study	VBN
cord-002180-gsdk5x3e	16	16	in	in	IN
cord-002180-gsdk5x3e	16	17	cell	cell	NN
cord-002180-gsdk5x3e	16	18	culture	culture	NN
cord-002180-gsdk5x3e	16	19	and	and	CC
cord-002180-gsdk5x3e	16	20	in	in	IN
cord-002180-gsdk5x3e	16	21	small	small	JJ
cord-002180-gsdk5x3e	16	22	animals	animal	NNS
cord-002180-gsdk5x3e	16	23	[	[	-LRB-
cord-002180-gsdk5x3e	16	24	7	7	CD
cord-002180-gsdk5x3e	16	25	]	]	-RRB-
cord-002180-gsdk5x3e	16	26	.	.	.
cord-002180-gsdk5x3e	17	1	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	17	2	is	be	VBZ
cord-002180-gsdk5x3e	17	3	a	a	DT
cord-002180-gsdk5x3e	17	4	positive	positive	JJ
cord-002180-gsdk5x3e	17	5	-	-	HYPH
cord-002180-gsdk5x3e	17	6	sense	sense	NN
cord-002180-gsdk5x3e	17	7	RNA	RNA	NNP
cord-002180-gsdk5x3e	17	8	virus	virus	NN
cord-002180-gsdk5x3e	17	9	of	of	IN
cord-002180-gsdk5x3e	17	10	approximately	approximately	RB
cord-002180-gsdk5x3e	17	11	7.4	7.4	CD
cord-002180-gsdk5x3e	17	12	kb	kb	NNP
cord-002180-gsdk5x3e	17	13	,	,	,
cord-002180-gsdk5x3e	17	14	containing	contain	VBG
cord-002180-gsdk5x3e	17	15	four	four	CD
cord-002180-gsdk5x3e	17	16	open	open	JJ
cord-002180-gsdk5x3e	17	17	reading	reading	NN
cord-002180-gsdk5x3e	17	18	frames	frame	NNS
cord-002180-gsdk5x3e	17	19	(	(	-LRB-
cord-002180-gsdk5x3e	17	20	ORF	ORF	NNP
cord-002180-gsdk5x3e	17	21	)	)	-RRB-
cord-002180-gsdk5x3e	17	22	.	.	.
cord-002180-gsdk5x3e	18	1	ORF1	ORF1	NNP
cord-002180-gsdk5x3e	18	2	encodes	encode	VBZ
cord-002180-gsdk5x3e	18	3	for	for	IN
cord-002180-gsdk5x3e	18	4	6	6	CD
cord-002180-gsdk5x3e	18	5	non	non	JJ
cord-002180-gsdk5x3e	18	6	-	-	JJ
cord-002180-gsdk5x3e	18	7	structural	structural	JJ
cord-002180-gsdk5x3e	18	8	proteins	protein	NNS
cord-002180-gsdk5x3e	18	9	(	(	-LRB-
cord-002180-gsdk5x3e	18	10	NS1	ns1	NN
cord-002180-gsdk5x3e	18	11	-	-	HYPH
cord-002180-gsdk5x3e	18	12	2	2	CD
cord-002180-gsdk5x3e	18	13	,	,	,
cord-002180-gsdk5x3e	18	14	NS3	ns3	RB
cord-002180-gsdk5x3e	18	15	,	,	,
cord-002180-gsdk5x3e	18	16	NS4	NS4	NNP
cord-002180-gsdk5x3e	18	17	,	,	,
cord-002180-gsdk5x3e	18	18	NS5	NS5	NNP
cord-002180-gsdk5x3e	18	19	,	,	,
cord-002180-gsdk5x3e	18	20	NS6	NS6	NNP
cord-002180-gsdk5x3e	18	21	,	,	,
cord-002180-gsdk5x3e	18	22	and	and	CC
cord-002180-gsdk5x3e	18	23	NS7	NS7	NNP
cord-002180-gsdk5x3e	18	24	)	)	-RRB-
cord-002180-gsdk5x3e	18	25	while	while	IN
cord-002180-gsdk5x3e	18	26	ORF2	ORF2	NNP
cord-002180-gsdk5x3e	18	27	and	and	CC
cord-002180-gsdk5x3e	18	28	ORF3	ORF3	NNP
cord-002180-gsdk5x3e	18	29	encode	encode	VBP
cord-002180-gsdk5x3e	18	30	the	the	DT
cord-002180-gsdk5x3e	18	31	major	major	JJ
cord-002180-gsdk5x3e	18	32	and	and	CC
cord-002180-gsdk5x3e	18	33	minor	minor	JJ
cord-002180-gsdk5x3e	18	34	structural	structural	JJ
cord-002180-gsdk5x3e	18	35	proteins	protein	NNS
cord-002180-gsdk5x3e	18	36	respectively	respectively	RB
cord-002180-gsdk5x3e	18	37	[	[	-LRB-
cord-002180-gsdk5x3e	18	38	8	8	CD
cord-002180-gsdk5x3e	18	39	]	]	-RRB-
cord-002180-gsdk5x3e	18	40	.	.	.
cord-002180-gsdk5x3e	19	1	ORF4	ORF4	NNP
cord-002180-gsdk5x3e	19	2	encodes	encode	VBZ
cord-002180-gsdk5x3e	19	3	for	for	IN
cord-002180-gsdk5x3e	19	4	virulence	virulence	NN
cord-002180-gsdk5x3e	19	5	factor	factor	NN
cord-002180-gsdk5x3e	19	6	1	1	CD
cord-002180-gsdk5x3e	19	7	,	,	,
cord-002180-gsdk5x3e	19	8	a	a	DT
cord-002180-gsdk5x3e	19	9	non	non	JJ
cord-002180-gsdk5x3e	19	10	-	-	JJ
cord-002180-gsdk5x3e	19	11	essential	essential	JJ
cord-002180-gsdk5x3e	19	12	protein	protein	NN
cord-002180-gsdk5x3e	19	13	involved	involve	VBN
cord-002180-gsdk5x3e	19	14	in	in	IN
cord-002180-gsdk5x3e	19	15	interactions	interaction	NNS
cord-002180-gsdk5x3e	19	16	with	with	IN
cord-002180-gsdk5x3e	19	17	host	host	NN
cord-002180-gsdk5x3e	19	18	apoptotic	apoptotic	JJ
cord-002180-gsdk5x3e	19	19	pathways	pathway	NNS
cord-002180-gsdk5x3e	19	20	[	[	-LRB-
cord-002180-gsdk5x3e	19	21	9	9	CD
cord-002180-gsdk5x3e	19	22	]	]	-RRB-
cord-002180-gsdk5x3e	19	23	.	.	.
cord-002180-gsdk5x3e	20	1	The	the	DT
cord-002180-gsdk5x3e	20	2	MNV	mnv	NN
cord-002180-gsdk5x3e	20	3	NS5	ns5	JJ
cord-002180-gsdk5x3e	20	4	(	(	-LRB-
cord-002180-gsdk5x3e	20	5	VPg	VPg	NNS
cord-002180-gsdk5x3e	20	6	;	;	:
cord-002180-gsdk5x3e	20	7	virus	virus	NN
cord-002180-gsdk5x3e	20	8	protein	protein	NN
cord-002180-gsdk5x3e	20	9	,	,	,
cord-002180-gsdk5x3e	20	10	genome	genome	NN
cord-002180-gsdk5x3e	20	11	linked	link	VBN
cord-002180-gsdk5x3e	20	12	)	)	-RRB-
cord-002180-gsdk5x3e	20	13	,	,	,
cord-002180-gsdk5x3e	20	14	is	be	VBZ
cord-002180-gsdk5x3e	20	15	a~16	a~16	NNP
cord-002180-gsdk5x3e	20	16	kDa	kDa	NNP
cord-002180-gsdk5x3e	20	17	protein	protein	NN
cord-002180-gsdk5x3e	20	18	that	that	WDT
cord-002180-gsdk5x3e	20	19	is	be	VBZ
cord-002180-gsdk5x3e	20	20	covalently	covalently	RB
cord-002180-gsdk5x3e	20	21	linked	link	VBN
cord-002180-gsdk5x3e	20	22	to	to	IN
cord-002180-gsdk5x3e	20	23	the	the	DT
cord-002180-gsdk5x3e	20	24	5	5	CD
cord-002180-gsdk5x3e	20	25	0	0	CD
cord-002180-gsdk5x3e	20	26	end	end	NN
cord-002180-gsdk5x3e	20	27	of	of	IN
cord-002180-gsdk5x3e	20	28	the	the	DT
cord-002180-gsdk5x3e	20	29	genomic	genomic	JJ
cord-002180-gsdk5x3e	20	30	and	and	CC
cord-002180-gsdk5x3e	20	31	subgenomic	subgenomic	NNP
cord-002180-gsdk5x3e	20	32	RNA	RNA	NNP
cord-002180-gsdk5x3e	20	33	[	[	-LRB-
cord-002180-gsdk5x3e	20	34	8	8	CD
cord-002180-gsdk5x3e	20	35	]	]	-RRB-
cord-002180-gsdk5x3e	20	36	.	.	.
cord-002180-gsdk5x3e	21	1	Linkage	linkage	NN
cord-002180-gsdk5x3e	21	2	to	to	IN
cord-002180-gsdk5x3e	21	3	the	the	DT
cord-002180-gsdk5x3e	21	4	genome	genome	NN
cord-002180-gsdk5x3e	21	5	is	be	VBZ
cord-002180-gsdk5x3e	21	6	thought	think	VBN
cord-002180-gsdk5x3e	21	7	to	to	TO
cord-002180-gsdk5x3e	21	8	prevent	prevent	VB
cord-002180-gsdk5x3e	21	9	detection	detection	NN
cord-002180-gsdk5x3e	21	10	by	by	IN
cord-002180-gsdk5x3e	21	11	host	host	NN
cord-002180-gsdk5x3e	21	12	pathogen	pathogen	NN
cord-002180-gsdk5x3e	21	13	recognition	recognition	NN
cord-002180-gsdk5x3e	21	14	receptors	receptor	NNS
cord-002180-gsdk5x3e	21	15	such	such	JJ
cord-002180-gsdk5x3e	21	16	as	as	IN
cord-002180-gsdk5x3e	21	17	RIG-1	RIG-1	NNS
cord-002180-gsdk5x3e	21	18	and	and	CC
cord-002180-gsdk5x3e	21	19	protein	protein	NN
cord-002180-gsdk5x3e	21	20	kinase	kinase	NN
cord-002180-gsdk5x3e	21	21	R	r	NN
cord-002180-gsdk5x3e	21	22	that	that	WDT
cord-002180-gsdk5x3e	21	23	detect	detect	VBP
cord-002180-gsdk5x3e	21	24	uncapped	uncapped	JJ
cord-002180-gsdk5x3e	21	25	5	5	CD
cord-002180-gsdk5x3e	21	26	0	0	CD
cord-002180-gsdk5x3e	21	27	triphosphorylated	triphosphorylate	VBN
cord-002180-gsdk5x3e	21	28	RNA	RNA	NNP
cord-002180-gsdk5x3e	21	29	,	,	,
cord-002180-gsdk5x3e	21	30	leading	lead	VBG
cord-002180-gsdk5x3e	21	31	to	to	IN
cord-002180-gsdk5x3e	21	32	an	an	DT
cord-002180-gsdk5x3e	21	33	antiviral	antiviral	JJ
cord-002180-gsdk5x3e	21	34	response	response	NN
cord-002180-gsdk5x3e	21	35	.	.	.
cord-002180-gsdk5x3e	22	1	NS5	NS5	NNP
cord-002180-gsdk5x3e	22	2	additionally	additionally	RB
cord-002180-gsdk5x3e	22	3	has	have	VBZ
cord-002180-gsdk5x3e	22	4	a	a	DT
cord-002180-gsdk5x3e	22	5	role	role	NN
cord-002180-gsdk5x3e	22	6	in	in	IN
cord-002180-gsdk5x3e	22	7	genome	genome	NN
cord-002180-gsdk5x3e	22	8	replication	replication	NN
cord-002180-gsdk5x3e	22	9	,	,	,
cord-002180-gsdk5x3e	22	10	acting	act	VBG
cord-002180-gsdk5x3e	22	11	in	in	IN
cord-002180-gsdk5x3e	22	12	place	place	NN
cord-002180-gsdk5x3e	22	13	of	of	IN
cord-002180-gsdk5x3e	22	14	an	an	DT
cord-002180-gsdk5x3e	22	15	RNA	RNA	NNP
cord-002180-gsdk5x3e	22	16	5	5	CD
cord-002180-gsdk5x3e	22	17	0	0	CD
cord-002180-gsdk5x3e	22	18	cap	cap	NN
cord-002180-gsdk5x3e	22	19	to	to	TO
cord-002180-gsdk5x3e	22	20	provide	provide	VB
cord-002180-gsdk5x3e	22	21	a	a	DT
cord-002180-gsdk5x3e	22	22	free	free	JJ
cord-002180-gsdk5x3e	22	23	hydroxyl	hydroxyl	NN
cord-002180-gsdk5x3e	22	24	that	that	WDT
cord-002180-gsdk5x3e	22	25	can	can	MD
cord-002180-gsdk5x3e	22	26	be	be	VB
cord-002180-gsdk5x3e	22	27	extended	extend	VBN
cord-002180-gsdk5x3e	22	28	by	by	IN
cord-002180-gsdk5x3e	22	29	the	the	DT
cord-002180-gsdk5x3e	22	30	virally	virally	RB
cord-002180-gsdk5x3e	22	31	encoded	encode	VBN
cord-002180-gsdk5x3e	22	32	RNA	rna	NN
cord-002180-gsdk5x3e	22	33	-	-	HYPH
cord-002180-gsdk5x3e	22	34	dependent	dependent	JJ
cord-002180-gsdk5x3e	22	35	RNA	RNA	NNP
cord-002180-gsdk5x3e	22	36	polymerase	polymerase	NN
cord-002180-gsdk5x3e	22	37	(	(	-LRB-
cord-002180-gsdk5x3e	22	38	NS7	NS7	NNP
cord-002180-gsdk5x3e	22	39	)	)	-RRB-
cord-002180-gsdk5x3e	22	40	[	[	-LRB-
cord-002180-gsdk5x3e	22	41	10	10	CD
cord-002180-gsdk5x3e	22	42	]	]	-RRB-
cord-002180-gsdk5x3e	22	43	.	.	.
cord-002180-gsdk5x3e	23	1	The	the	DT
cord-002180-gsdk5x3e	23	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	23	3	protein	protein	NN
cord-002180-gsdk5x3e	23	4	also	also	RB
cord-002180-gsdk5x3e	23	5	acts	act	VBZ
cord-002180-gsdk5x3e	23	6	to	to	TO
cord-002180-gsdk5x3e	23	7	aid	aid	VB
cord-002180-gsdk5x3e	23	8	viral	viral	JJ
cord-002180-gsdk5x3e	23	9	translation	translation	NN
cord-002180-gsdk5x3e	23	10	,	,	,
cord-002180-gsdk5x3e	23	11	recruiting	recruit	VBG
cord-002180-gsdk5x3e	23	12	host	host	NN
cord-002180-gsdk5x3e	23	13	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	23	14	translation	translation	NN
cord-002180-gsdk5x3e	23	15	initiation	initiation	NN
cord-002180-gsdk5x3e	23	16	factors	factor	NNS
cord-002180-gsdk5x3e	23	17	to	to	TO
cord-002180-gsdk5x3e	23	18	initiate	initiate	VB
cord-002180-gsdk5x3e	23	19	translation	translation	NN
cord-002180-gsdk5x3e	23	20	of	of	IN
cord-002180-gsdk5x3e	23	21	viral	viral	JJ
cord-002180-gsdk5x3e	23	22	proteins	protein	NNS
cord-002180-gsdk5x3e	23	23	[	[	-LRB-
cord-002180-gsdk5x3e	23	24	11	11	CD
cord-002180-gsdk5x3e	23	25	]	]	-RRB-
cord-002180-gsdk5x3e	23	26	.	.	.
cord-002180-gsdk5x3e	24	1	The	the	DT
cord-002180-gsdk5x3e	24	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	24	3	protein	protein	NN
cord-002180-gsdk5x3e	24	4	also	also	RB
cord-002180-gsdk5x3e	24	5	contains	contain	VBZ
cord-002180-gsdk5x3e	24	6	regions	region	NNS
cord-002180-gsdk5x3e	24	7	of	of	IN
cord-002180-gsdk5x3e	24	8	predicted	predict	VBN
cord-002180-gsdk5x3e	24	9	disorder	disorder	NN
cord-002180-gsdk5x3e	24	10	that	that	WDT
cord-002180-gsdk5x3e	24	11	are	be	VBP
cord-002180-gsdk5x3e	24	12	often	often	RB
cord-002180-gsdk5x3e	24	13	associated	associate	VBN
cord-002180-gsdk5x3e	24	14	with	with	IN
cord-002180-gsdk5x3e	24	15	multiple	multiple	JJ
cord-002180-gsdk5x3e	24	16	functions	function	NNS
cord-002180-gsdk5x3e	24	17	[	[	-LRB-
cord-002180-gsdk5x3e	24	18	12	12	CD
cord-002180-gsdk5x3e	24	19	,	,	,
cord-002180-gsdk5x3e	24	20	13	13	CD
cord-002180-gsdk5x3e	24	21	]	]	-RRB-
cord-002180-gsdk5x3e	24	22	.	.	.
cord-002180-gsdk5x3e	25	1	As	as	IN
cord-002180-gsdk5x3e	25	2	more	more	JJR
cord-002180-gsdk5x3e	25	3	viruses	virus	NNS
cord-002180-gsdk5x3e	25	4	are	be	VBP
cord-002180-gsdk5x3e	25	5	characterized	characterize	VBN
cord-002180-gsdk5x3e	25	6	,	,	,
cord-002180-gsdk5x3e	25	7	it	-PRON-	PRP
cord-002180-gsdk5x3e	25	8	is	be	VBZ
cord-002180-gsdk5x3e	25	9	becoming	become	VBG
cord-002180-gsdk5x3e	25	10	increasingly	increasingly	RB
cord-002180-gsdk5x3e	25	11	common	common	JJ
cord-002180-gsdk5x3e	25	12	to	to	TO
cord-002180-gsdk5x3e	25	13	observe	observe	VB
cord-002180-gsdk5x3e	25	14	interactions	interaction	NNS
cord-002180-gsdk5x3e	25	15	between	between	IN
cord-002180-gsdk5x3e	25	16	viral	viral	JJ
cord-002180-gsdk5x3e	25	17	replication	replication	NN
cord-002180-gsdk5x3e	25	18	and	and	CC
cord-002180-gsdk5x3e	25	19	the	the	DT
cord-002180-gsdk5x3e	25	20	host	host	NN
cord-002180-gsdk5x3e	25	21	cell	cell	NN
cord-002180-gsdk5x3e	25	22	cycle	cycle	NN
cord-002180-gsdk5x3e	25	23	.	.	.
cord-002180-gsdk5x3e	26	1	Each	each	DT
cord-002180-gsdk5x3e	26	2	phase	phase	NN
cord-002180-gsdk5x3e	26	3	of	of	IN
cord-002180-gsdk5x3e	26	4	the	the	DT
cord-002180-gsdk5x3e	26	5	cell	cell	NN
cord-002180-gsdk5x3e	26	6	cycle	cycle	NN
cord-002180-gsdk5x3e	26	7	presents	present	VBZ
cord-002180-gsdk5x3e	26	8	distinctive	distinctive	JJ
cord-002180-gsdk5x3e	26	9	biological	biological	JJ
cord-002180-gsdk5x3e	26	10	conditions	condition	NNS
cord-002180-gsdk5x3e	26	11	that	that	WDT
cord-002180-gsdk5x3e	26	12	have	have	VBP
cord-002180-gsdk5x3e	26	13	a	a	DT
cord-002180-gsdk5x3e	26	14	significant	significant	JJ
cord-002180-gsdk5x3e	26	15	impact	impact	NN
cord-002180-gsdk5x3e	26	16	on	on	IN
cord-002180-gsdk5x3e	26	17	viral	viral	JJ
cord-002180-gsdk5x3e	26	18	replication	replication	NN
cord-002180-gsdk5x3e	26	19	.	.	.
cord-002180-gsdk5x3e	27	1	Many	many	JJ
cord-002180-gsdk5x3e	27	2	viruses	virus	NNS
cord-002180-gsdk5x3e	27	3	can	can	MD
cord-002180-gsdk5x3e	27	4	subvert	subvert	VB
cord-002180-gsdk5x3e	27	5	the	the	DT
cord-002180-gsdk5x3e	27	6	host	host	NN
cord-002180-gsdk5x3e	27	7	cell	cell	NN
cord-002180-gsdk5x3e	27	8	division	division	NN
cord-002180-gsdk5x3e	27	9	in	in	IN
cord-002180-gsdk5x3e	27	10	order	order	NN
cord-002180-gsdk5x3e	27	11	to	to	TO
cord-002180-gsdk5x3e	27	12	create	create	VB
cord-002180-gsdk5x3e	27	13	an	an	DT
cord-002180-gsdk5x3e	27	14	environment	environment	NN
cord-002180-gsdk5x3e	27	15	where	where	WRB
cord-002180-gsdk5x3e	27	16	viral	viral	JJ
cord-002180-gsdk5x3e	27	17	propagation	propagation	NN
cord-002180-gsdk5x3e	27	18	is	be	VBZ
cord-002180-gsdk5x3e	27	19	preferred	prefer	VBN
cord-002180-gsdk5x3e	27	20	.	.	.
cord-002180-gsdk5x3e	28	1	Several	several	JJ
cord-002180-gsdk5x3e	28	2	RNA	RNA	NNP
cord-002180-gsdk5x3e	28	3	viruses	virus	NNS
cord-002180-gsdk5x3e	28	4	,	,	,
cord-002180-gsdk5x3e	28	5	including	include	VBG
cord-002180-gsdk5x3e	28	6	murine	murine	JJ
cord-002180-gsdk5x3e	28	7	norovirus	norovirus	NN
cord-002180-gsdk5x3e	28	8	1	1	CD
cord-002180-gsdk5x3e	28	9	(	(	-LRB-
cord-002180-gsdk5x3e	28	10	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	28	11	)	)	-RRB-
cord-002180-gsdk5x3e	28	12	have	have	VBP
cord-002180-gsdk5x3e	28	13	been	be	VBN
cord-002180-gsdk5x3e	28	14	characterized	characterize	VBN
cord-002180-gsdk5x3e	28	15	to	to	TO
cord-002180-gsdk5x3e	28	16	manipulate	manipulate	VB
cord-002180-gsdk5x3e	28	17	cell	cell	NN
cord-002180-gsdk5x3e	28	18	cycle	cycle	NN
cord-002180-gsdk5x3e	28	19	progression	progression	NN
cord-002180-gsdk5x3e	28	20	at	at	IN
cord-002180-gsdk5x3e	28	21	the	the	DT
cord-002180-gsdk5x3e	28	22	G	g	NN
cord-002180-gsdk5x3e	28	23	1	1	CD
cord-002180-gsdk5x3e	28	24	/S	/S	NNP
cord-002180-gsdk5x3e	28	25	restriction	restriction	NN
cord-002180-gsdk5x3e	28	26	point	point	NN
cord-002180-gsdk5x3e	28	27	,	,	,
cord-002180-gsdk5x3e	28	28	often	often	RB
cord-002180-gsdk5x3e	28	29	creating	create	VBG
cord-002180-gsdk5x3e	28	30	favorable	favorable	JJ
cord-002180-gsdk5x3e	28	31	conditions	condition	NNS
cord-002180-gsdk5x3e	28	32	for	for	IN
cord-002180-gsdk5x3e	28	33	viral	viral	JJ
cord-002180-gsdk5x3e	28	34	replication	replication	NN
cord-002180-gsdk5x3e	28	35	[	[	-LRB-
cord-002180-gsdk5x3e	28	36	14	14	CD
cord-002180-gsdk5x3e	28	37	]	]	-RRB-
cord-002180-gsdk5x3e	28	38	[	[	-LRB-
cord-002180-gsdk5x3e	28	39	15	15	CD
cord-002180-gsdk5x3e	28	40	]	]	-RRB-
cord-002180-gsdk5x3e	28	41	[	[	-LRB-
cord-002180-gsdk5x3e	28	42	16	16	CD
cord-002180-gsdk5x3e	28	43	]	]	-RRB-
cord-002180-gsdk5x3e	28	44	[	[	-LRB-
cord-002180-gsdk5x3e	28	45	17	17	CD
cord-002180-gsdk5x3e	28	46	]	]	-RRB-
cord-002180-gsdk5x3e	28	47	[	[	-LRB-
cord-002180-gsdk5x3e	28	48	18	18	CD
cord-002180-gsdk5x3e	28	49	]	]	-RRB-
cord-002180-gsdk5x3e	28	50	[	[	-LRB-
cord-002180-gsdk5x3e	28	51	19	19	CD
cord-002180-gsdk5x3e	28	52	]	]	-RRB-
cord-002180-gsdk5x3e	28	53	[	[	-LRB-
cord-002180-gsdk5x3e	28	54	20	20	CD
cord-002180-gsdk5x3e	28	55	]	]	-RRB-
cord-002180-gsdk5x3e	28	56	[	[	-LRB-
cord-002180-gsdk5x3e	28	57	21	21	CD
cord-002180-gsdk5x3e	28	58	]	]	-RRB-
cord-002180-gsdk5x3e	28	59	.	.	.
cord-002180-gsdk5x3e	29	1	Cell	cell	NN
cord-002180-gsdk5x3e	29	2	cycle	cycle	NN
cord-002180-gsdk5x3e	29	3	progression	progression	NN
cord-002180-gsdk5x3e	29	4	is	be	VBZ
cord-002180-gsdk5x3e	29	5	a	a	DT
cord-002180-gsdk5x3e	29	6	complex	complex	JJ
cord-002180-gsdk5x3e	29	7	process	process	NN
cord-002180-gsdk5x3e	29	8	that	that	WDT
cord-002180-gsdk5x3e	29	9	is	be	VBZ
cord-002180-gsdk5x3e	29	10	tightly	tightly	RB
cord-002180-gsdk5x3e	29	11	controlled	control	VBN
cord-002180-gsdk5x3e	29	12	by	by	IN
cord-002180-gsdk5x3e	29	13	multiple	multiple	JJ
cord-002180-gsdk5x3e	29	14	pathways	pathway	NNS
cord-002180-gsdk5x3e	29	15	.	.	.
cord-002180-gsdk5x3e	30	1	The	the	DT
cord-002180-gsdk5x3e	30	2	G	g	NN
cord-002180-gsdk5x3e	30	3	1	1	CD
cord-002180-gsdk5x3e	30	4	/S	/S	NNP
cord-002180-gsdk5x3e	30	5	checkpoint	checkpoint	NNP
cord-002180-gsdk5x3e	30	6	controls	control	VBZ
cord-002180-gsdk5x3e	30	7	progression	progression	NN
cord-002180-gsdk5x3e	30	8	from	from	IN
cord-002180-gsdk5x3e	30	9	the	the	DT
cord-002180-gsdk5x3e	30	10	first	first	JJ
cord-002180-gsdk5x3e	30	11	gap	gap	NN
cord-002180-gsdk5x3e	30	12	phase	phase	NN
cord-002180-gsdk5x3e	30	13	(	(	-LRB-
cord-002180-gsdk5x3e	30	14	G	g	NN
cord-002180-gsdk5x3e	30	15	1	1	CD
cord-002180-gsdk5x3e	30	16	)	)	-RRB-
cord-002180-gsdk5x3e	30	17	,	,	,
cord-002180-gsdk5x3e	30	18	a	a	DT
cord-002180-gsdk5x3e	30	19	period	period	NN
cord-002180-gsdk5x3e	30	20	of	of	IN
cord-002180-gsdk5x3e	30	21	substantial	substantial	JJ
cord-002180-gsdk5x3e	30	22	cell	cell	NN
cord-002180-gsdk5x3e	30	23	growth	growth	NN
cord-002180-gsdk5x3e	30	24	,	,	,
cord-002180-gsdk5x3e	30	25	into	into	IN
cord-002180-gsdk5x3e	30	26	the	the	DT
cord-002180-gsdk5x3e	30	27	synthesis	synthesis	NN
cord-002180-gsdk5x3e	30	28	phase	phase	NN
cord-002180-gsdk5x3e	30	29	(	(	-LRB-
cord-002180-gsdk5x3e	30	30	S	S	NNP
cord-002180-gsdk5x3e	30	31	)	)	-RRB-
cord-002180-gsdk5x3e	30	32	where	where	WRB
cord-002180-gsdk5x3e	30	33	the	the	DT
cord-002180-gsdk5x3e	30	34	host	host	NN
cord-002180-gsdk5x3e	30	35	DNA	dna	NN
cord-002180-gsdk5x3e	30	36	is	be	VBZ
cord-002180-gsdk5x3e	30	37	replicated	replicate	VBN
cord-002180-gsdk5x3e	30	38	.	.	.
cord-002180-gsdk5x3e	31	1	Progression	progression	NN
cord-002180-gsdk5x3e	31	2	through	through	IN
cord-002180-gsdk5x3e	31	3	G	g	NN
cord-002180-gsdk5x3e	31	4	1	1	CD
cord-002180-gsdk5x3e	31	5	/S	/S	NNPS
cord-002180-gsdk5x3e	31	6	is	be	VBZ
cord-002180-gsdk5x3e	31	7	predominantly	predominantly	RB
cord-002180-gsdk5x3e	31	8	controlled	control	VBN
cord-002180-gsdk5x3e	31	9	by	by	IN
cord-002180-gsdk5x3e	31	10	the	the	DT
cord-002180-gsdk5x3e	31	11	phosphorylation	phosphorylation	NN
cord-002180-gsdk5x3e	31	12	status	status	NN
cord-002180-gsdk5x3e	31	13	of	of	IN
cord-002180-gsdk5x3e	31	14	the	the	DT
cord-002180-gsdk5x3e	31	15	retinoblastoma	retinoblastoma	NN
cord-002180-gsdk5x3e	31	16	protein	protein	NN
cord-002180-gsdk5x3e	31	17	(	(	-LRB-
cord-002180-gsdk5x3e	31	18	pRb	pRb	NNP
cord-002180-gsdk5x3e	31	19	)	)	-RRB-
cord-002180-gsdk5x3e	31	20	,	,	,
cord-002180-gsdk5x3e	31	21	which	which	WDT
cord-002180-gsdk5x3e	31	22	is	be	VBZ
cord-002180-gsdk5x3e	31	23	in	in	IN
cord-002180-gsdk5x3e	31	24	turn	turn	NN
cord-002180-gsdk5x3e	31	25	controlled	control	VBN
cord-002180-gsdk5x3e	31	26	by	by	IN
cord-002180-gsdk5x3e	31	27	the	the	DT
cord-002180-gsdk5x3e	31	28	activities	activity	NNS
cord-002180-gsdk5x3e	31	29	of	of	IN
cord-002180-gsdk5x3e	31	30	cyclins	cyclin	NNS
cord-002180-gsdk5x3e	31	31	and	and	CC
cord-002180-gsdk5x3e	31	32	cyclin	cyclin	NN
cord-002180-gsdk5x3e	31	33	-	-	HYPH
cord-002180-gsdk5x3e	31	34	dependent	dependent	JJ
cord-002180-gsdk5x3e	31	35	kinases	kinase	NNS
cord-002180-gsdk5x3e	31	36	(	(	-LRB-
cord-002180-gsdk5x3e	31	37	CDK	CDK	NNP
cord-002180-gsdk5x3e	31	38	)	)	-RRB-
cord-002180-gsdk5x3e	31	39	(	(	-LRB-
cord-002180-gsdk5x3e	31	40	reviewed	review	VBN
cord-002180-gsdk5x3e	31	41	in	in	IN
cord-002180-gsdk5x3e	31	42	[	[	-LRB-
cord-002180-gsdk5x3e	31	43	22	22	CD
cord-002180-gsdk5x3e	31	44	]	]	-RRB-
cord-002180-gsdk5x3e	31	45	)	)	-RRB-
cord-002180-gsdk5x3e	31	46	.	.	.
cord-002180-gsdk5x3e	32	1	Cyclins	cyclin	NNS
cord-002180-gsdk5x3e	32	2	are	be	VBP
cord-002180-gsdk5x3e	32	3	expressed	express	VBN
cord-002180-gsdk5x3e	32	4	at	at	IN
cord-002180-gsdk5x3e	32	5	various	various	JJ
cord-002180-gsdk5x3e	32	6	stages	stage	NNS
cord-002180-gsdk5x3e	32	7	of	of	IN
cord-002180-gsdk5x3e	32	8	cell	cell	NN
cord-002180-gsdk5x3e	32	9	division	division	NN
cord-002180-gsdk5x3e	32	10	and	and	CC
cord-002180-gsdk5x3e	32	11	bind	bind	VB
cord-002180-gsdk5x3e	32	12	to	to	IN
cord-002180-gsdk5x3e	32	13	their	-PRON-	PRP$
cord-002180-gsdk5x3e	32	14	corresponding	corresponding	JJ
cord-002180-gsdk5x3e	32	15	CDK	CDK	NNP
cord-002180-gsdk5x3e	32	16	and	and	CC
cord-002180-gsdk5x3e	32	17	phosphorylate	phosphorylate	VBP
cord-002180-gsdk5x3e	32	18	numerous	numerous	JJ
cord-002180-gsdk5x3e	32	19	targets	target	NNS
cord-002180-gsdk5x3e	32	20	including	include	VBG
cord-002180-gsdk5x3e	32	21	pRb	prb	NN
cord-002180-gsdk5x3e	32	22	.	.	.
cord-002180-gsdk5x3e	33	1	In	in	IN
cord-002180-gsdk5x3e	33	2	early	early	JJ
cord-002180-gsdk5x3e	33	3	G	g	NN
cord-002180-gsdk5x3e	33	4	1	1	CD
cord-002180-gsdk5x3e	33	5	phase	phase	NN
cord-002180-gsdk5x3e	33	6	,	,	,
cord-002180-gsdk5x3e	33	7	cyclin	cyclin	NN
cord-002180-gsdk5x3e	33	8	D	D	NNP
cord-002180-gsdk5x3e	33	9	family	family	NN
cord-002180-gsdk5x3e	33	10	members	member	NNS
cord-002180-gsdk5x3e	33	11	bind	bind	VBP
cord-002180-gsdk5x3e	33	12	to	to	IN
cord-002180-gsdk5x3e	33	13	CDK4/6	CDK4/6	.
cord-002180-gsdk5x3e	34	1	and	and	CC
cord-002180-gsdk5x3e	34	2	phosphorylate	phosphorylate	VB
cord-002180-gsdk5x3e	34	3	pRb	prb	NN
cord-002180-gsdk5x3e	34	4	,	,	,
cord-002180-gsdk5x3e	34	5	driving	drive	VBG
cord-002180-gsdk5x3e	34	6	G	g	NN
cord-002180-gsdk5x3e	34	7	1	1	CD
cord-002180-gsdk5x3e	34	8	phase	phase	NN
cord-002180-gsdk5x3e	34	9	progression	progression	NN
cord-002180-gsdk5x3e	34	10	and	and	CC
cord-002180-gsdk5x3e	34	11	expression	expression	NN
cord-002180-gsdk5x3e	34	12	of	of	IN
cord-002180-gsdk5x3e	34	13	E	e	NN
cord-002180-gsdk5x3e	34	14	and	and	CC
cord-002180-gsdk5x3e	34	15	A	a	DT
cord-002180-gsdk5x3e	34	16	cyclins	cyclin	NNS
cord-002180-gsdk5x3e	34	17	.	.	.
cord-002180-gsdk5x3e	35	1	Cyclin	Cyclin	NNP
cord-002180-gsdk5x3e	35	2	E	E	NNP
cord-002180-gsdk5x3e	35	3	forms	form	VBZ
cord-002180-gsdk5x3e	35	4	a	a	DT
cord-002180-gsdk5x3e	35	5	complex	complex	NN
cord-002180-gsdk5x3e	35	6	with	with	IN
cord-002180-gsdk5x3e	35	7	CDK2	CDK2	NNP
cord-002180-gsdk5x3e	35	8	,	,	,
cord-002180-gsdk5x3e	35	9	which	which	WDT
cord-002180-gsdk5x3e	35	10	further	further	RB
cord-002180-gsdk5x3e	35	11	phosphorylates	phosphorylate	VBZ
cord-002180-gsdk5x3e	35	12	pRb	prb	NN
cord-002180-gsdk5x3e	35	13	to	to	TO
cord-002180-gsdk5x3e	35	14	release	release	VB
cord-002180-gsdk5x3e	35	15	an	an	DT
cord-002180-gsdk5x3e	35	16	E2F	e2f	NN
cord-002180-gsdk5x3e	35	17	transcription	transcription	NN
cord-002180-gsdk5x3e	35	18	factor	factor	NN
cord-002180-gsdk5x3e	35	19	,	,	,
cord-002180-gsdk5x3e	35	20	driving	drive	VBG
cord-002180-gsdk5x3e	35	21	S	s	NN
cord-002180-gsdk5x3e	35	22	phase	phase	NN
cord-002180-gsdk5x3e	35	23	entry	entry	NN
cord-002180-gsdk5x3e	35	24	[	[	-LRB-
cord-002180-gsdk5x3e	35	25	23	23	CD
cord-002180-gsdk5x3e	35	26	]	]	-RRB-
cord-002180-gsdk5x3e	35	27	.	.	.
cord-002180-gsdk5x3e	36	1	Cyclin	Cyclin	NNP
cord-002180-gsdk5x3e	36	2	A	a	DT
cord-002180-gsdk5x3e	36	3	levels	level	NNS
cord-002180-gsdk5x3e	36	4	continue	continue	VBP
cord-002180-gsdk5x3e	36	5	to	to	TO
cord-002180-gsdk5x3e	36	6	increase	increase	VB
cord-002180-gsdk5x3e	36	7	during	during	IN
cord-002180-gsdk5x3e	36	8	S	s	NN
cord-002180-gsdk5x3e	36	9	phase	phase	NN
cord-002180-gsdk5x3e	36	10	and	and	CC
cord-002180-gsdk5x3e	36	11	help	help	VB
cord-002180-gsdk5x3e	36	12	drive	drive	VB
cord-002180-gsdk5x3e	36	13	cell	cell	NN
cord-002180-gsdk5x3e	36	14	cycle	cycle	NN
cord-002180-gsdk5x3e	36	15	progression	progression	NN
cord-002180-gsdk5x3e	36	16	through	through	IN
cord-002180-gsdk5x3e	36	17	the	the	DT
cord-002180-gsdk5x3e	36	18	later	later	JJ
cord-002180-gsdk5x3e	36	19	stages	stage	NNS
cord-002180-gsdk5x3e	36	20	of	of	IN
cord-002180-gsdk5x3e	36	21	the	the	DT
cord-002180-gsdk5x3e	36	22	cell	cell	NN
cord-002180-gsdk5x3e	36	23	cycle	cycle	NN
cord-002180-gsdk5x3e	36	24	,	,	,
cord-002180-gsdk5x3e	36	25	through	through	IN
cord-002180-gsdk5x3e	36	26	to	to	IN
cord-002180-gsdk5x3e	36	27	the	the	DT
cord-002180-gsdk5x3e	36	28	initiation	initiation	NN
cord-002180-gsdk5x3e	36	29	of	of	IN
cord-002180-gsdk5x3e	36	30	prophase	prophase	NN
cord-002180-gsdk5x3e	36	31	during	during	IN
cord-002180-gsdk5x3e	36	32	mitosis	mitosis	NN
cord-002180-gsdk5x3e	36	33	[	[	-LRB-
cord-002180-gsdk5x3e	36	34	24	24	CD
cord-002180-gsdk5x3e	36	35	,	,	,
cord-002180-gsdk5x3e	36	36	25	25	CD
cord-002180-gsdk5x3e	36	37	]	]	-RRB-
cord-002180-gsdk5x3e	36	38	.	.	.
cord-002180-gsdk5x3e	37	1	Recently	recently	RB
cord-002180-gsdk5x3e	37	2	,	,	,
cord-002180-gsdk5x3e	37	3	we	-PRON-	PRP
cord-002180-gsdk5x3e	37	4	have	have	VBP
cord-002180-gsdk5x3e	37	5	shown	show	VBN
cord-002180-gsdk5x3e	37	6	that	that	IN
cord-002180-gsdk5x3e	37	7	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	37	8	is	be	VBZ
cord-002180-gsdk5x3e	37	9	able	able	JJ
cord-002180-gsdk5x3e	37	10	to	to	TO
cord-002180-gsdk5x3e	37	11	manipulate	manipulate	VB
cord-002180-gsdk5x3e	37	12	the	the	DT
cord-002180-gsdk5x3e	37	13	host	host	NN
cord-002180-gsdk5x3e	37	14	cell	cell	NN
cord-002180-gsdk5x3e	37	15	division	division	NN
cord-002180-gsdk5x3e	37	16	in	in	IN
cord-002180-gsdk5x3e	37	17	murine	murine	JJ
cord-002180-gsdk5x3e	37	18	macrophages	macrophage	NNS
cord-002180-gsdk5x3e	37	19	,	,	,
cord-002180-gsdk5x3e	37	20	inducing	induce	VBG
cord-002180-gsdk5x3e	37	21	an	an	DT
cord-002180-gsdk5x3e	37	22	accumulation	accumulation	NN
cord-002180-gsdk5x3e	37	23	of	of	IN
cord-002180-gsdk5x3e	37	24	cells	cell	NNS
cord-002180-gsdk5x3e	37	25	in	in	IN
cord-002180-gsdk5x3e	37	26	the	the	DT
cord-002180-gsdk5x3e	37	27	G	g	NN
cord-002180-gsdk5x3e	37	28	0	0	CD
cord-002180-gsdk5x3e	37	29	/G	/g	SYM
cord-002180-gsdk5x3e	37	30	1	1	CD
cord-002180-gsdk5x3e	37	31	phase	phase	NN
cord-002180-gsdk5x3e	37	32	due	due	IN
cord-002180-gsdk5x3e	37	33	to	to	IN
cord-002180-gsdk5x3e	37	34	an	an	DT
cord-002180-gsdk5x3e	37	35	arrest	arrest	NN
cord-002180-gsdk5x3e	37	36	at	at	IN
cord-002180-gsdk5x3e	37	37	the	the	DT
cord-002180-gsdk5x3e	37	38	G	g	NN
cord-002180-gsdk5x3e	37	39	1	1	CD
cord-002180-gsdk5x3e	37	40	/S	/S	NNP
cord-002180-gsdk5x3e	37	41	restriction	restriction	NN
cord-002180-gsdk5x3e	37	42	point	point	NN
cord-002180-gsdk5x3e	37	43	[	[	-LRB-
cord-002180-gsdk5x3e	37	44	20	20	CD
cord-002180-gsdk5x3e	37	45	]	]	-RRB-
cord-002180-gsdk5x3e	37	46	.	.	.
cord-002180-gsdk5x3e	38	1	Additionally	additionally	RB
cord-002180-gsdk5x3e	38	2	,	,	,
cord-002180-gsdk5x3e	38	3	this	this	DT
cord-002180-gsdk5x3e	38	4	G	g	NN
cord-002180-gsdk5x3e	38	5	1	1	CD
cord-002180-gsdk5x3e	38	6	/S	/S	NNP
cord-002180-gsdk5x3e	38	7	arrest	arrest	NN
cord-002180-gsdk5x3e	38	8	created	create	VBN
cord-002180-gsdk5x3e	38	9	conditions	condition	NNS
cord-002180-gsdk5x3e	38	10	where	where	WRB
cord-002180-gsdk5x3e	38	11	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	38	12	replication	replication	NN
cord-002180-gsdk5x3e	38	13	was	be	VBD
cord-002180-gsdk5x3e	38	14	favored	favor	VBN
cord-002180-gsdk5x3e	38	15	compared	compare	VBN
cord-002180-gsdk5x3e	38	16	to	to	IN
cord-002180-gsdk5x3e	38	17	other	other	JJ
cord-002180-gsdk5x3e	38	18	stages	stage	NNS
cord-002180-gsdk5x3e	38	19	of	of	IN
cord-002180-gsdk5x3e	38	20	the	the	DT
cord-002180-gsdk5x3e	38	21	cell	cell	NN
cord-002180-gsdk5x3e	38	22	cycle	cycle	NN
cord-002180-gsdk5x3e	38	23	.	.	.
cord-002180-gsdk5x3e	39	1	In	in	IN
cord-002180-gsdk5x3e	39	2	this	this	DT
cord-002180-gsdk5x3e	39	3	study	study	NN
cord-002180-gsdk5x3e	39	4	,	,	,
cord-002180-gsdk5x3e	39	5	we	-PRON-	PRP
cord-002180-gsdk5x3e	39	6	show	show	VBP
cord-002180-gsdk5x3e	39	7	that	that	IN
cord-002180-gsdk5x3e	39	8	expression	expression	NN
cord-002180-gsdk5x3e	39	9	of	of	IN
cord-002180-gsdk5x3e	39	10	viral	viral	JJ
cord-002180-gsdk5x3e	39	11	NS5	ns5	JJ
cord-002180-gsdk5x3e	39	12	protein	protein	NN
cord-002180-gsdk5x3e	39	13	in	in	IN
cord-002180-gsdk5x3e	39	14	cell	cell	NN
cord-002180-gsdk5x3e	39	15	culture	culture	NN
cord-002180-gsdk5x3e	39	16	induces	induce	VBZ
cord-002180-gsdk5x3e	39	17	an	an	DT
cord-002180-gsdk5x3e	39	18	accumulation	accumulation	NN
cord-002180-gsdk5x3e	39	19	of	of	IN
cord-002180-gsdk5x3e	39	20	cells	cell	NNS
cord-002180-gsdk5x3e	39	21	in	in	IN
cord-002180-gsdk5x3e	39	22	the	the	DT
cord-002180-gsdk5x3e	39	23	G	g	NN
cord-002180-gsdk5x3e	39	24	0	0	CD
cord-002180-gsdk5x3e	39	25	/G	/g	SYM
cord-002180-gsdk5x3e	39	26	1	1	CD
cord-002180-gsdk5x3e	39	27	phase	phase	NN
cord-002180-gsdk5x3e	39	28	through	through	IN
cord-002180-gsdk5x3e	39	29	a	a	DT
cord-002180-gsdk5x3e	39	30	G	g	NN
cord-002180-gsdk5x3e	39	31	1	1	CD
cord-002180-gsdk5x3e	39	32	/S	/S	NNP
cord-002180-gsdk5x3e	39	33	arrest	arrest	NN
cord-002180-gsdk5x3e	39	34	in	in	IN
cord-002180-gsdk5x3e	39	35	an	an	DT
cord-002180-gsdk5x3e	39	36	analogous	analogous	JJ
cord-002180-gsdk5x3e	39	37	manner	manner	NN
cord-002180-gsdk5x3e	39	38	to	to	IN
cord-002180-gsdk5x3e	39	39	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	39	40	infection	infection	NN
cord-002180-gsdk5x3e	39	41	.	.	.
cord-002180-gsdk5x3e	40	1	Furthermore	furthermore	RB
cord-002180-gsdk5x3e	40	2	,	,	,
cord-002180-gsdk5x3e	40	3	the	the	DT
cord-002180-gsdk5x3e	40	4	effects	effect	NNS
cord-002180-gsdk5x3e	40	5	of	of	IN
cord-002180-gsdk5x3e	40	6	NS5	NS5	NNP
cord-002180-gsdk5x3e	40	7	on	on	IN
cord-002180-gsdk5x3e	40	8	the	the	DT
cord-002180-gsdk5x3e	40	9	host	host	NN
cord-002180-gsdk5x3e	40	10	cell	cell	NN
cord-002180-gsdk5x3e	40	11	cycle	cycle	NN
cord-002180-gsdk5x3e	40	12	are	be	VBP
cord-002180-gsdk5x3e	40	13	independent	independent	JJ
cord-002180-gsdk5x3e	40	14	of	of	IN
cord-002180-gsdk5x3e	40	15	the	the	DT
cord-002180-gsdk5x3e	40	16	known	know	VBN
cord-002180-gsdk5x3e	40	17	replication	replication	NN
cord-002180-gsdk5x3e	40	18	and	and	CC
cord-002180-gsdk5x3e	40	19	translation	translation	NN
cord-002180-gsdk5x3e	40	20	activities	activity	NNS
cord-002180-gsdk5x3e	40	21	attributed	attribute	VBN
cord-002180-gsdk5x3e	40	22	to	to	IN
cord-002180-gsdk5x3e	40	23	NS5	ns5	JJ
cord-002180-gsdk5x3e	40	24	(	(	-LRB-
cord-002180-gsdk5x3e	40	25	VPg	VPg	NNS
cord-002180-gsdk5x3e	40	26	)	)	-RRB-
cord-002180-gsdk5x3e	40	27	.	.	.
cord-002180-gsdk5x3e	41	1	RAW	raw	JJ
cord-002180-gsdk5x3e	41	2	-	-	HYPH
cord-002180-gsdk5x3e	41	3	Blue	blue	JJ
cord-002180-gsdk5x3e	41	4	cells	cell	NNS
cord-002180-gsdk5x3e	41	5	,	,	,
cord-002180-gsdk5x3e	41	6	a	a	DT
cord-002180-gsdk5x3e	41	7	mouse	mouse	NN
cord-002180-gsdk5x3e	41	8	leukemic	leukemic	JJ
cord-002180-gsdk5x3e	41	9	monocyte	monocyte	NNP
cord-002180-gsdk5x3e	41	10	macrophage	macrophage	NN
cord-002180-gsdk5x3e	41	11	cell	cell	NN
cord-002180-gsdk5x3e	41	12	line	line	NN
cord-002180-gsdk5x3e	41	13	(	(	-LRB-
cord-002180-gsdk5x3e	41	14	obtained	obtain	VBN
cord-002180-gsdk5x3e	41	15	from	from	IN
cord-002180-gsdk5x3e	41	16	InvivoGen	InvivoGen	NNP
cord-002180-gsdk5x3e	41	17	,	,	,
cord-002180-gsdk5x3e	41	18	San	San	NNP
cord-002180-gsdk5x3e	41	19	Diego	Diego	NNP
cord-002180-gsdk5x3e	41	20	,	,	,
cord-002180-gsdk5x3e	41	21	CA	CA	NNP
cord-002180-gsdk5x3e	41	22	)	)	-RRB-
cord-002180-gsdk5x3e	41	23	were	be	VBD
cord-002180-gsdk5x3e	41	24	maintained	maintain	VBN
cord-002180-gsdk5x3e	41	25	in	in	IN
cord-002180-gsdk5x3e	41	26	Dulbecco	Dulbecco	NNP
cord-002180-gsdk5x3e	41	27	's	's	POS
cord-002180-gsdk5x3e	41	28	modified	modify	VBN
cord-002180-gsdk5x3e	41	29	Eagle	Eagle	NNP
cord-002180-gsdk5x3e	41	30	's	's	POS
cord-002180-gsdk5x3e	41	31	medium	medium	NN
cord-002180-gsdk5x3e	41	32	(	(	-LRB-
cord-002180-gsdk5x3e	41	33	DMEM	DMEM	NNP
cord-002180-gsdk5x3e	41	34	)	)	-RRB-
cord-002180-gsdk5x3e	42	1	(	(	-LRB-
cord-002180-gsdk5x3e	42	2	Life	Life	NNP
cord-002180-gsdk5x3e	42	3	Technologies	Technologies	NNPS
cord-002180-gsdk5x3e	42	4	,	,	,
cord-002180-gsdk5x3e	42	5	Gaithersburg	Gaithersburg	NNP
cord-002180-gsdk5x3e	42	6	,	,	,
cord-002180-gsdk5x3e	42	7	MD	MD	NNP
cord-002180-gsdk5x3e	42	8	)	)	-RRB-
cord-002180-gsdk5x3e	42	9	containing	contain	VBG
cord-002180-gsdk5x3e	42	10	10	10	CD
cord-002180-gsdk5x3e	42	11	%	%	NN
cord-002180-gsdk5x3e	42	12	heat	heat	NN
cord-002180-gsdk5x3e	42	13	-	-	HYPH
cord-002180-gsdk5x3e	42	14	inactivated	inactivate	VBN
cord-002180-gsdk5x3e	42	15	fetal	fetal	JJ
cord-002180-gsdk5x3e	42	16	calf	calf	NN
cord-002180-gsdk5x3e	42	17	serum	serum	NN
cord-002180-gsdk5x3e	42	18	(	(	-LRB-
cord-002180-gsdk5x3e	42	19	Thermo	Thermo	NNP
cord-002180-gsdk5x3e	42	20	Fisher	Fisher	NNP
cord-002180-gsdk5x3e	42	21	Scientific	Scientific	NNP
cord-002180-gsdk5x3e	42	22	)	)	-RRB-
cord-002180-gsdk5x3e	42	23	,	,	,
cord-002180-gsdk5x3e	42	24	penicillin	penicillin	NN
cord-002180-gsdk5x3e	42	25	(	(	-LRB-
cord-002180-gsdk5x3e	42	26	100	100	CD
cord-002180-gsdk5x3e	42	27	U	U	NNP
cord-002180-gsdk5x3e	42	28	/	/	SYM
cord-002180-gsdk5x3e	42	29	ml	ml	NN
cord-002180-gsdk5x3e	42	30	)	)	-RRB-
cord-002180-gsdk5x3e	42	31	,	,	,
cord-002180-gsdk5x3e	42	32	streptomycin	streptomycin	NNS
cord-002180-gsdk5x3e	42	33	(	(	-LRB-
cord-002180-gsdk5x3e	42	34	0.1	0.1	CD
cord-002180-gsdk5x3e	42	35	mg	mg	NNP
cord-002180-gsdk5x3e	42	36	/	/	SYM
cord-002180-gsdk5x3e	42	37	ml	ml	NNP
cord-002180-gsdk5x3e	42	38	)	)	-RRB-
cord-002180-gsdk5x3e	42	39	,	,	,
cord-002180-gsdk5x3e	42	40	normocin	normocin	NNP
cord-002180-gsdk5x3e	42	41	(	(	-LRB-
cord-002180-gsdk5x3e	42	42	100	100	CD
cord-002180-gsdk5x3e	42	43	μg	μg	NN
cord-002180-gsdk5x3e	42	44	/	/	SYM
cord-002180-gsdk5x3e	42	45	ml	ml	NNP
cord-002180-gsdk5x3e	42	46	)	)	-RRB-
cord-002180-gsdk5x3e	42	47	and	and	CC
cord-002180-gsdk5x3e	42	48	zeocin	zeocin	NNP
cord-002180-gsdk5x3e	42	49	(	(	-LRB-
cord-002180-gsdk5x3e	42	50	200	200	CD
cord-002180-gsdk5x3e	42	51	μg	μg	NN
cord-002180-gsdk5x3e	42	52	/	/	SYM
cord-002180-gsdk5x3e	42	53	ml	ml	NN
cord-002180-gsdk5x3e	42	54	)	)	-RRB-
cord-002180-gsdk5x3e	42	55	(	(	-LRB-
cord-002180-gsdk5x3e	42	56	Life	Life	NNP
cord-002180-gsdk5x3e	42	57	Technologies	Technologies	NNPS
cord-002180-gsdk5x3e	42	58	)	)	-RRB-
cord-002180-gsdk5x3e	42	59	.	.	.
cord-002180-gsdk5x3e	43	1	Cells	cell	NNS
cord-002180-gsdk5x3e	43	2	were	be	VBD
cord-002180-gsdk5x3e	43	3	maintained	maintain	VBN
cord-002180-gsdk5x3e	43	4	at	at	IN
cord-002180-gsdk5x3e	43	5	37	37	CD
cord-002180-gsdk5x3e	43	6	°	°	NN
cord-002180-gsdk5x3e	43	7	C	c	NN
cord-002180-gsdk5x3e	43	8	in	in	IN
cord-002180-gsdk5x3e	43	9	a	a	DT
cord-002180-gsdk5x3e	43	10	5	5	CD
cord-002180-gsdk5x3e	43	11	%	%	NN
cord-002180-gsdk5x3e	43	12	CO	co	NN
cord-002180-gsdk5x3e	43	13	2	2	CD
cord-002180-gsdk5x3e	43	14	humidified	humidify	VBN
cord-002180-gsdk5x3e	43	15	atmosphere	atmosphere	NN
cord-002180-gsdk5x3e	43	16	and	and	CC
cord-002180-gsdk5x3e	43	17	passaged	passage	VBD
cord-002180-gsdk5x3e	43	18	every	every	DT
cord-002180-gsdk5x3e	43	19	48	48	CD
cord-002180-gsdk5x3e	43	20	h.	h.	NN
cord-002180-gsdk5x3e	43	21	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	43	22	NS1	NS1	NNP
cord-002180-gsdk5x3e	43	23	-	-	HYPH
cord-002180-gsdk5x3e	43	24	2	2	CD
cord-002180-gsdk5x3e	43	25	and	and	CC
cord-002180-gsdk5x3e	43	26	NS5	ns5	JJ
cord-002180-gsdk5x3e	43	27	sequences	sequence	NNS
cord-002180-gsdk5x3e	43	28	were	be	VBD
cord-002180-gsdk5x3e	43	29	amplified	amplify	VBN
cord-002180-gsdk5x3e	43	30	from	from	IN
cord-002180-gsdk5x3e	43	31	the	the	DT
cord-002180-gsdk5x3e	43	32	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	43	33	infectious	infectious	JJ
cord-002180-gsdk5x3e	43	34	clone	clone	NN
cord-002180-gsdk5x3e	43	35	pMNV	pmnv	NN
cord-002180-gsdk5x3e	43	36	Ã	Ã	NNP
cord-002180-gsdk5x3e	43	37	,	,	,
cord-002180-gsdk5x3e	43	38	derived	derive	VBN
cord-002180-gsdk5x3e	43	39	from	from	IN
cord-002180-gsdk5x3e	43	40	MNV	mnv	NN
cord-002180-gsdk5x3e	43	41	strain	strain	NN
cord-002180-gsdk5x3e	44	1	CW1	CW1	NNP
cord-002180-gsdk5x3e	44	2	(	(	-LRB-
cord-002180-gsdk5x3e	44	3	GenBank	GenBank	NNP
cord-002180-gsdk5x3e	44	4	Accession	Accession	NNP
cord-002180-gsdk5x3e	44	5	DQ285629	dq285629	NN
cord-002180-gsdk5x3e	44	6	)	)	-RRB-
cord-002180-gsdk5x3e	45	1	as	as	IN
cord-002180-gsdk5x3e	45	2	described	describe	VBN
cord-002180-gsdk5x3e	45	3	in	in	IN
cord-002180-gsdk5x3e	45	4	Ward	Ward	NNP
cord-002180-gsdk5x3e	45	5	et	et	NNP
cord-002180-gsdk5x3e	45	6	al	al	NNP
cord-002180-gsdk5x3e	45	7	[	[	-LRB-
cord-002180-gsdk5x3e	45	8	26	26	CD
cord-002180-gsdk5x3e	45	9	]	]	-RRB-
cord-002180-gsdk5x3e	45	10	,	,	,
cord-002180-gsdk5x3e	45	11	and	and	CC
cord-002180-gsdk5x3e	45	12	the	the	DT
cord-002180-gsdk5x3e	45	13	PCR	PCR	NNP
cord-002180-gsdk5x3e	45	14	products	product	NNS
cord-002180-gsdk5x3e	45	15	ligated	ligate	VBN
cord-002180-gsdk5x3e	45	16	into	into	IN
cord-002180-gsdk5x3e	45	17	pUC8	pUC8	NNP
cord-002180-gsdk5x3e	45	18	and	and	CC
cord-002180-gsdk5x3e	45	19	the	the	DT
cord-002180-gsdk5x3e	45	20	sequence	sequence	NN
cord-002180-gsdk5x3e	45	21	verified	verify	VBN
cord-002180-gsdk5x3e	45	22	.	.	.
cord-002180-gsdk5x3e	46	1	Primers	primer	NNS
cord-002180-gsdk5x3e	46	2	used	use	VBN
cord-002180-gsdk5x3e	46	3	for	for	IN
cord-002180-gsdk5x3e	46	4	NS1	ns1	NN
cord-002180-gsdk5x3e	46	5	-	-	HYPH
cord-002180-gsdk5x3e	46	6	2	2	CD
cord-002180-gsdk5x3e	46	7	amplification	amplification	NN
cord-002180-gsdk5x3e	46	8	were	be	VBD
cord-002180-gsdk5x3e	46	9	5	5	CD
cord-002180-gsdk5x3e	46	10	0	0	CD
cord-002180-gsdk5x3e	46	11	GAAATTAATACGACTCACTATAGTGAAATGAGGATGGC	GAAATTAATACGACTCACTATAGTGAAATGAGGATGGC	NNP
cord-002180-gsdk5x3e	46	12	AACGCCATC	AACGCCATC	NNP
cord-002180-gsdk5x3e	46	13	3	3	CD
cord-002180-gsdk5x3e	46	14	0	0	NFP
cord-002180-gsdk5x3e	46	15	(	(	-LRB-
cord-002180-gsdk5x3e	46	16	forward	forward	RB
cord-002180-gsdk5x3e	46	17	)	)	-RRB-
cord-002180-gsdk5x3e	46	18	and	and	CC
cord-002180-gsdk5x3e	46	19	5	5	CD
cord-002180-gsdk5x3e	46	20	0	0	CD
cord-002180-gsdk5x3e	46	21	AGCAAGGTCGAAGGGTTATTCGGC	AGCAAGGTCGAAGGGTTATTCGGC	NNP
cord-002180-gsdk5x3e	46	22	3	3	CD
cord-002180-gsdk5x3e	46	23	0	0	NFP
cord-002180-gsdk5x3e	46	24	(	(	-LRB-
cord-002180-gsdk5x3e	46	25	reverse	reverse	NN
cord-002180-gsdk5x3e	46	26	)	)	-RRB-
cord-002180-gsdk5x3e	46	27	and	and	CC
cord-002180-gsdk5x3e	46	28	for	for	IN
cord-002180-gsdk5x3e	46	29	NS5	ns5	JJ
cord-002180-gsdk5x3e	46	30	5	5	CD
cord-002180-gsdk5x3e	46	31	0	0	CD
cord-002180-gsdk5x3e	46	32	GAAATTAATACGACTCACTATAGGGAGAATGGGAAAGAAGGGCAAGA`3	gaaattaatacgactcactatagggagaatgggaaagaagggcaaga`3	CD
cord-002180-gsdk5x3e	46	33	0	0	NFP
cord-002180-gsdk5x3e	46	34	(	(	-LRB-
cord-002180-gsdk5x3e	46	35	reverse	reverse	NN
cord-002180-gsdk5x3e	46	36	)	)	-RRB-
cord-002180-gsdk5x3e	46	37	.	.	.
cord-002180-gsdk5x3e	47	1	Each	each	DT
cord-002180-gsdk5x3e	47	2	forward	forward	JJ
cord-002180-gsdk5x3e	47	3	primer	primer	NN
cord-002180-gsdk5x3e	47	4	added	add	VBD
cord-002180-gsdk5x3e	47	5	a	a	DT
cord-002180-gsdk5x3e	47	6	GAAAT	GAAAT	NNP
cord-002180-gsdk5x3e	47	7	motif	motif	NN
cord-002180-gsdk5x3e	47	8	and	and	CC
cord-002180-gsdk5x3e	47	9	a	a	DT
cord-002180-gsdk5x3e	47	10	T7	t7	NN
cord-002180-gsdk5x3e	47	11	promoter	promoter	NN
cord-002180-gsdk5x3e	47	12	(	(	-LRB-
cord-002180-gsdk5x3e	47	13	underlined	underline	VBN
cord-002180-gsdk5x3e	47	14	)	)	-RRB-
cord-002180-gsdk5x3e	47	15	to	to	IN
cord-002180-gsdk5x3e	47	16	the	the	DT
cord-002180-gsdk5x3e	47	17	5	5	CD
cord-002180-gsdk5x3e	47	18	0	0	CD
cord-002180-gsdk5x3e	47	19	end	end	NN
cord-002180-gsdk5x3e	47	20	of	of	IN
cord-002180-gsdk5x3e	47	21	the	the	DT
cord-002180-gsdk5x3e	47	22	insert	insert	NN
cord-002180-gsdk5x3e	47	23	for	for	IN
cord-002180-gsdk5x3e	47	24	T7	T7	NNP
cord-002180-gsdk5x3e	47	25	RNA	RNA	NNP
cord-002180-gsdk5x3e	47	26	polymerase	polymerase	NN
cord-002180-gsdk5x3e	47	27	binding	bind	VBG
cord-002180-gsdk5x3e	47	28	as	as	IN
cord-002180-gsdk5x3e	47	29	recommended	recommend	VBN
cord-002180-gsdk5x3e	47	30	for	for	IN
cord-002180-gsdk5x3e	47	31	mMessage	mMessage	NNP
cord-002180-gsdk5x3e	47	32	Machine	Machine	NNP
cord-002180-gsdk5x3e	47	33	in	in	IN
cord-002180-gsdk5x3e	47	34	vitro	vitro	FW
cord-002180-gsdk5x3e	47	35	RNA	RNA	NNP
cord-002180-gsdk5x3e	47	36	transcript	transcript	NN
cord-002180-gsdk5x3e	47	37	production	production	NN
cord-002180-gsdk5x3e	47	38	(	(	-LRB-
cord-002180-gsdk5x3e	47	39	Ambion	Ambion	NNP
cord-002180-gsdk5x3e	47	40	)	)	-RRB-
cord-002180-gsdk5x3e	47	41	.	.	.
cord-002180-gsdk5x3e	48	1	Bold	bold	JJ
cord-002180-gsdk5x3e	48	2	sequences	sequence	NNS
cord-002180-gsdk5x3e	48	3	indicate	indicate	VBP
cord-002180-gsdk5x3e	48	4	start	start	NN
cord-002180-gsdk5x3e	48	5	(	(	-LRB-
cord-002180-gsdk5x3e	48	6	ATG	ATG	NNP
cord-002180-gsdk5x3e	48	7	)	)	-RRB-
cord-002180-gsdk5x3e	48	8	or	or	CC
cord-002180-gsdk5x3e	48	9	stop	stop	VB
cord-002180-gsdk5x3e	48	10	(	(	-LRB-
cord-002180-gsdk5x3e	48	11	TTA	TTA	NNP
cord-002180-gsdk5x3e	48	12	)	)	-RRB-
cord-002180-gsdk5x3e	48	13	codons	codon	NNS
cord-002180-gsdk5x3e	48	14	.	.	.
cord-002180-gsdk5x3e	49	1	The	the	DT
cord-002180-gsdk5x3e	49	2	expression	expression	NN
cord-002180-gsdk5x3e	49	3	constructs	construct	VBZ
cord-002180-gsdk5x3e	49	4	matched	match	VBD
cord-002180-gsdk5x3e	49	5	the	the	DT
cord-002180-gsdk5x3e	49	6	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	49	7	NS1	NS1	NNP
cord-002180-gsdk5x3e	49	8	-	-	HYPH
cord-002180-gsdk5x3e	49	9	2	2	CD
cord-002180-gsdk5x3e	49	10	and	and	CC
cord-002180-gsdk5x3e	49	11	NS5	ns5	JJ
cord-002180-gsdk5x3e	49	12	sequences	sequence	NNS
cord-002180-gsdk5x3e	49	13	except	except	IN
cord-002180-gsdk5x3e	49	14	for	for	IN
cord-002180-gsdk5x3e	49	15	the	the	DT
cord-002180-gsdk5x3e	49	16	addition	addition	NN
cord-002180-gsdk5x3e	49	17	of	of	IN
cord-002180-gsdk5x3e	49	18	a	a	DT
cord-002180-gsdk5x3e	49	19	methionine	methionine	NN
cord-002180-gsdk5x3e	49	20	codon	codon	NN
cord-002180-gsdk5x3e	49	21	at	at	IN
cord-002180-gsdk5x3e	49	22	the	the	DT
cord-002180-gsdk5x3e	49	23	5	5	CD
cord-002180-gsdk5x3e	49	24	0	0	CD
cord-002180-gsdk5x3e	49	25	end	end	NN
cord-002180-gsdk5x3e	49	26	of	of	IN
cord-002180-gsdk5x3e	49	27	the	the	DT
cord-002180-gsdk5x3e	49	28	NS5	ns5	JJ
cord-002180-gsdk5x3e	49	29	coding	coding	NN
cord-002180-gsdk5x3e	49	30	sequence	sequence	NN
cord-002180-gsdk5x3e	49	31	to	to	TO
cord-002180-gsdk5x3e	49	32	facilitate	facilitate	VB
cord-002180-gsdk5x3e	49	33	translation	translation	NN
cord-002180-gsdk5x3e	49	34	and	and	CC
cord-002180-gsdk5x3e	49	35	stop	stop	VB
cord-002180-gsdk5x3e	49	36	codons	codon	NNS
cord-002180-gsdk5x3e	49	37	in	in	IN
cord-002180-gsdk5x3e	49	38	the	the	DT
cord-002180-gsdk5x3e	49	39	NS1	ns1	NN
cord-002180-gsdk5x3e	49	40	-	-	HYPH
cord-002180-gsdk5x3e	49	41	2	2	CD
cord-002180-gsdk5x3e	49	42	and	and	CC
cord-002180-gsdk5x3e	49	43	NS5	ns5	JJ
cord-002180-gsdk5x3e	49	44	constructs	construct	NNS
cord-002180-gsdk5x3e	49	45	to	to	TO
cord-002180-gsdk5x3e	49	46	terminate	terminate	VB
cord-002180-gsdk5x3e	49	47	translation	translation	NN
cord-002180-gsdk5x3e	49	48	.	.	.
cord-002180-gsdk5x3e	50	1	The	the	DT
cord-002180-gsdk5x3e	50	2	resulting	result	VBG
cord-002180-gsdk5x3e	50	3	plasmids	plasmid	NNS
cord-002180-gsdk5x3e	50	4	were	be	VBD
cord-002180-gsdk5x3e	50	5	transformed	transform	VBN
cord-002180-gsdk5x3e	50	6	into	into	IN
cord-002180-gsdk5x3e	50	7	XL1-Blue	XL1-Blue	NNP
cord-002180-gsdk5x3e	50	8	MRF	MRF	NNP
cord-002180-gsdk5x3e	50	9	0	0	CD
cord-002180-gsdk5x3e	50	10	Escherichia	escherichia	NN
cord-002180-gsdk5x3e	50	11	coli	coli	NNS
cord-002180-gsdk5x3e	50	12	cells	cell	NNS
cord-002180-gsdk5x3e	50	13	and	and	CC
cord-002180-gsdk5x3e	50	14	used	use	VBD
cord-002180-gsdk5x3e	50	15	as	as	IN
cord-002180-gsdk5x3e	50	16	templates	template	NNS
cord-002180-gsdk5x3e	50	17	for	for	IN
cord-002180-gsdk5x3e	50	18	in	in	FW
cord-002180-gsdk5x3e	50	19	vitro	vitro	FW
cord-002180-gsdk5x3e	50	20	RNA	RNA	NNP
cord-002180-gsdk5x3e	50	21	synthesis	synthesis	NN
cord-002180-gsdk5x3e	50	22	.	.	.
cord-002180-gsdk5x3e	51	1	Cloning	clone	VBG
cord-002180-gsdk5x3e	51	2	of	of	IN
cord-002180-gsdk5x3e	51	3	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	51	4	)	)	-RRB-
cord-002180-gsdk5x3e	51	5	and	and	CC
cord-002180-gsdk5x3e	51	6	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	51	7	)	)	-RRB-
cord-002180-gsdk5x3e	51	8	.	.	.
cord-002180-gsdk5x3e	52	1	Constructs	construct	NNS
cord-002180-gsdk5x3e	52	2	for	for	IN
cord-002180-gsdk5x3e	52	3	the	the	DT
cord-002180-gsdk5x3e	52	4	expression	expression	NN
cord-002180-gsdk5x3e	52	5	of	of	IN
cord-002180-gsdk5x3e	52	6	NS5	ns5	JJ
cord-002180-gsdk5x3e	52	7	variants	variant	NNS
cord-002180-gsdk5x3e	52	8	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	52	9	)	)	-RRB-
cord-002180-gsdk5x3e	52	10	and	and	CC
cord-002180-gsdk5x3e	52	11	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	52	12	)	)	-RRB-
cord-002180-gsdk5x3e	52	13	were	be	VBD
cord-002180-gsdk5x3e	52	14	designed	design	VBN
cord-002180-gsdk5x3e	52	15	with	with	IN
cord-002180-gsdk5x3e	52	16	the	the	DT
cord-002180-gsdk5x3e	52	17	requirements	requirement	NNS
cord-002180-gsdk5x3e	52	18	for	for	IN
cord-002180-gsdk5x3e	52	19	RNA	RNA	NNP
cord-002180-gsdk5x3e	52	20	synthesis	synthesis	NN
cord-002180-gsdk5x3e	52	21	and	and	CC
cord-002180-gsdk5x3e	52	22	translation	translation	NN
cord-002180-gsdk5x3e	52	23	and	and	CC
cord-002180-gsdk5x3e	52	24	were	be	VBD
cord-002180-gsdk5x3e	52	25	synthesized	synthesize	VBN
cord-002180-gsdk5x3e	52	26	by	by	IN
cord-002180-gsdk5x3e	52	27	GenScript	GenScript	NNP
cord-002180-gsdk5x3e	52	28	and	and	CC
cord-002180-gsdk5x3e	52	29	cloned	clone	VBN
cord-002180-gsdk5x3e	52	30	into	into	IN
cord-002180-gsdk5x3e	52	31	a	a	DT
cord-002180-gsdk5x3e	52	32	pUC57-Simple	puc57-simple	NN
cord-002180-gsdk5x3e	52	33	vector	vector	NN
cord-002180-gsdk5x3e	52	34	(	(	-LRB-
cord-002180-gsdk5x3e	52	35	Gen	Gen	NNP
cord-002180-gsdk5x3e	52	36	-	-	HYPH
cord-002180-gsdk5x3e	52	37	Script	Script	NNP
cord-002180-gsdk5x3e	52	38	,	,	,
cord-002180-gsdk5x3e	52	39	Piscataway	Piscataway	NNP
cord-002180-gsdk5x3e	52	40	,	,	,
cord-002180-gsdk5x3e	52	41	NJ	NJ	NNP
cord-002180-gsdk5x3e	52	42	,	,	,
cord-002180-gsdk5x3e	52	43	USA	USA	NNP
cord-002180-gsdk5x3e	52	44	)	)	-RRB-
cord-002180-gsdk5x3e	52	45	[	[	-LRB-
cord-002180-gsdk5x3e	52	46	27	27	CD
cord-002180-gsdk5x3e	52	47	]	]	-RRB-
cord-002180-gsdk5x3e	52	48	.	.	.
cord-002180-gsdk5x3e	53	1	The	the	DT
cord-002180-gsdk5x3e	53	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	53	3	sequences	sequence	NNS
cord-002180-gsdk5x3e	53	4	(	(	-LRB-
cord-002180-gsdk5x3e	53	5	GenBank	GenBank	NNP
cord-002180-gsdk5x3e	53	6	Accession	Accession	NNP
cord-002180-gsdk5x3e	53	7	DQ285629	dq285629	NN
cord-002180-gsdk5x3e	53	8	)	)	-RRB-
cord-002180-gsdk5x3e	53	9	were	be	VBD
cord-002180-gsdk5x3e	53	10	flanked	flank	VBN
cord-002180-gsdk5x3e	53	11	at	at	IN
cord-002180-gsdk5x3e	53	12	the	the	DT
cord-002180-gsdk5x3e	53	13	5	5	CD
cord-002180-gsdk5x3e	53	14	0	0	CD
cord-002180-gsdk5x3e	53	15	end	end	NN
cord-002180-gsdk5x3e	53	16	by	by	IN
cord-002180-gsdk5x3e	53	17	a	a	DT
cord-002180-gsdk5x3e	53	18	BamHI	bamhi	NN
cord-002180-gsdk5x3e	53	19	restriction	restriction	NN
cord-002180-gsdk5x3e	53	20	site	site	NN
cord-002180-gsdk5x3e	53	21	,	,	,
cord-002180-gsdk5x3e	53	22	a	a	DT
cord-002180-gsdk5x3e	53	23	T7	T7	NNP
cord-002180-gsdk5x3e	53	24	promoter	promoter	NN
cord-002180-gsdk5x3e	53	25	sequence	sequence	NN
cord-002180-gsdk5x3e	53	26	(	(	-LRB-
cord-002180-gsdk5x3e	53	27	underlined	underline	VBN
cord-002180-gsdk5x3e	53	28	)	)	-RRB-
cord-002180-gsdk5x3e	53	29	,	,	,
cord-002180-gsdk5x3e	53	30	a	a	DT
cord-002180-gsdk5x3e	53	31	Kozak	Kozak	NNP
cord-002180-gsdk5x3e	53	32	sequence	sequence	NN
cord-002180-gsdk5x3e	53	33	for	for	IN
cord-002180-gsdk5x3e	53	34	optimal	optimal	JJ
cord-002180-gsdk5x3e	53	35	RNA	RNA	NNP
cord-002180-gsdk5x3e	53	36	translation	translation	NN
cord-002180-gsdk5x3e	53	37	and	and	CC
cord-002180-gsdk5x3e	53	38	a	a	DT
cord-002180-gsdk5x3e	53	39	methionine	methionine	NN
cord-002180-gsdk5x3e	53	40	codon	codon	NN
cord-002180-gsdk5x3e	53	41	(	(	-LRB-
cord-002180-gsdk5x3e	53	42	bold	bold	JJ
cord-002180-gsdk5x3e	53	43	)	)	-RRB-
cord-002180-gsdk5x3e	53	44	(	(	-LRB-
cord-002180-gsdk5x3e	53	45	GGATCCGAA	GGATCCGAA	NNP
cord-002180-gsdk5x3e	53	46	ATTAATACGACTCACTATAGGGAGAATG	ATTAATACGACTCACTATAGGGAGAATG	NNP
cord-002180-gsdk5x3e	53	47	)	)	-RRB-
cord-002180-gsdk5x3e	53	48	.	.	.
cord-002180-gsdk5x3e	54	1	Flanking	flank	VBG
cord-002180-gsdk5x3e	54	2	the	the	DT
cord-002180-gsdk5x3e	54	3	3	3	CD
cord-002180-gsdk5x3e	54	4	0	0	CD
cord-002180-gsdk5x3e	54	5	end	end	NN
cord-002180-gsdk5x3e	54	6	of	of	IN
cord-002180-gsdk5x3e	54	7	the	the	DT
cord-002180-gsdk5x3e	54	8	NS5	ns5	JJ
cord-002180-gsdk5x3e	54	9	sequence	sequence	NN
cord-002180-gsdk5x3e	54	10	was	be	VBD
cord-002180-gsdk5x3e	54	11	a	a	DT
cord-002180-gsdk5x3e	54	12	stop	stop	NN
cord-002180-gsdk5x3e	54	13	codon	codon	NN
cord-002180-gsdk5x3e	54	14	(	(	-LRB-
cord-002180-gsdk5x3e	54	15	bold	bold	JJ
cord-002180-gsdk5x3e	54	16	)	)	-RRB-
cord-002180-gsdk5x3e	54	17	and	and	CC
cord-002180-gsdk5x3e	54	18	a	a	DT
cord-002180-gsdk5x3e	54	19	HindIII	HindIII	NNP
cord-002180-gsdk5x3e	54	20	restriction	restriction	NN
cord-002180-gsdk5x3e	54	21	site	site	NN
cord-002180-gsdk5x3e	54	22	(	(	-LRB-
cord-002180-gsdk5x3e	54	23	TGAAAGCTT	TGAAAGCTT	NNP
cord-002180-gsdk5x3e	54	24	)	)	-RRB-
cord-002180-gsdk5x3e	54	25	.	.	.
cord-002180-gsdk5x3e	55	1	The	the	DT
cord-002180-gsdk5x3e	55	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	55	3	variants	variant	NNS
cord-002180-gsdk5x3e	55	4	sequences	sequence	NNS
cord-002180-gsdk5x3e	55	5	had	have	VBD
cord-002180-gsdk5x3e	55	6	alanine	alanine	JJ
cord-002180-gsdk5x3e	55	7	substitutions	substitution	NNS
cord-002180-gsdk5x3e	55	8	inserted	insert	VBN
cord-002180-gsdk5x3e	55	9	at	at	IN
cord-002180-gsdk5x3e	55	10	the	the	DT
cord-002180-gsdk5x3e	55	11	tyrosine	tyrosine	NN
cord-002180-gsdk5x3e	55	12	26	26	CD
cord-002180-gsdk5x3e	55	13	and	and	CC
cord-002180-gsdk5x3e	55	14	phenylalanine	phenylalanine	NN
cord-002180-gsdk5x3e	55	15	123	123	CD
cord-002180-gsdk5x3e	55	16	,	,	,
cord-002180-gsdk5x3e	55	17	named	name	VBN
cord-002180-gsdk5x3e	55	18	NS5	NS5	NNP
cord-002180-gsdk5x3e	55	19	(	(	-LRB-
cord-002180-gsdk5x3e	55	20	Y26A	Y26A	NNP
cord-002180-gsdk5x3e	55	21	)	)	-RRB-
cord-002180-gsdk5x3e	55	22	and	and	CC
cord-002180-gsdk5x3e	55	23	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	55	24	)	)	-RRB-
cord-002180-gsdk5x3e	55	25	respectively	respectively	RB
cord-002180-gsdk5x3e	55	26	.	.	.
cord-002180-gsdk5x3e	56	1	The	the	DT
cord-002180-gsdk5x3e	56	2	resulting	result	VBG
cord-002180-gsdk5x3e	56	3	plasmids	plasmid	NNS
cord-002180-gsdk5x3e	56	4	were	be	VBD
cord-002180-gsdk5x3e	56	5	transformed	transform	VBN
cord-002180-gsdk5x3e	56	6	into	into	IN
cord-002180-gsdk5x3e	56	7	XL1-Blue	XL1-Blue	NNP
cord-002180-gsdk5x3e	56	8	MRF	MRF	NNP
cord-002180-gsdk5x3e	56	9	0	0	CD
cord-002180-gsdk5x3e	56	10	E.	E.	NNP
cord-002180-gsdk5x3e	56	11	coli	coli	NNS
cord-002180-gsdk5x3e	56	12	cells	cell	NNS
cord-002180-gsdk5x3e	56	13	and	and	CC
cord-002180-gsdk5x3e	56	14	used	use	VBD
cord-002180-gsdk5x3e	56	15	as	as	IN
cord-002180-gsdk5x3e	56	16	templates	template	NNS
cord-002180-gsdk5x3e	56	17	for	for	IN
cord-002180-gsdk5x3e	56	18	in	in	FW
cord-002180-gsdk5x3e	56	19	vitro	vitro	FW
cord-002180-gsdk5x3e	56	20	RNA	RNA	NNP
cord-002180-gsdk5x3e	56	21	synthesis	synthesis	NN
cord-002180-gsdk5x3e	56	22	.	.	.
cord-002180-gsdk5x3e	57	1	In	in	IN
cord-002180-gsdk5x3e	57	2	vitro	vitro	FW
cord-002180-gsdk5x3e	57	3	RNA	RNA	NNP
cord-002180-gsdk5x3e	57	4	synthesis	synthesis	NN
cord-002180-gsdk5x3e	57	5	.	.	.
cord-002180-gsdk5x3e	58	1	Plasmids	plasmid	NNS
cord-002180-gsdk5x3e	58	2	were	be	VBD
cord-002180-gsdk5x3e	58	3	linearized	linearize	VBN
cord-002180-gsdk5x3e	58	4	at	at	IN
cord-002180-gsdk5x3e	58	5	the	the	DT
cord-002180-gsdk5x3e	58	6	3	3	CD
cord-002180-gsdk5x3e	58	7	0	0	CD
cord-002180-gsdk5x3e	58	8	end	end	NN
cord-002180-gsdk5x3e	58	9	of	of	IN
cord-002180-gsdk5x3e	58	10	viral	viral	JJ
cord-002180-gsdk5x3e	58	11	genes	gene	NNS
cord-002180-gsdk5x3e	58	12	with	with	IN
cord-002180-gsdk5x3e	58	13	EcoRI	ecori	NN
cord-002180-gsdk5x3e	58	14	(	(	-LRB-
cord-002180-gsdk5x3e	58	15	for	for	IN
cord-002180-gsdk5x3e	58	16	NS1	ns1	NN
cord-002180-gsdk5x3e	58	17	-	-	HYPH
cord-002180-gsdk5x3e	58	18	2	2	CD
cord-002180-gsdk5x3e	58	19	)	)	-RRB-
cord-002180-gsdk5x3e	58	20	,	,	,
cord-002180-gsdk5x3e	58	21	AvaI	AvaI	NNP
cord-002180-gsdk5x3e	58	22	(	(	-LRB-
cord-002180-gsdk5x3e	58	23	for	for	IN
cord-002180-gsdk5x3e	58	24	NS5	NS5	NNP
cord-002180-gsdk5x3e	58	25	)	)	-RRB-
cord-002180-gsdk5x3e	58	26	or	or	CC
cord-002180-gsdk5x3e	58	27	HindIII	HindIII	NNP
cord-002180-gsdk5x3e	58	28	(	(	-LRB-
cord-002180-gsdk5x3e	58	29	for	for	IN
cord-002180-gsdk5x3e	58	30	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	58	31	)	)	-RRB-
cord-002180-gsdk5x3e	58	32	and	and	CC
cord-002180-gsdk5x3e	58	33	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	58	34	)	)	-RRB-
cord-002180-gsdk5x3e	58	35	)	)	-RRB-
cord-002180-gsdk5x3e	58	36	.	.	.
cord-002180-gsdk5x3e	59	1	Subsequently	subsequently	RB
cord-002180-gsdk5x3e	59	2	,	,	,
cord-002180-gsdk5x3e	59	3	messenger	messenger	NN
cord-002180-gsdk5x3e	59	4	RNA	RNA	NNP
cord-002180-gsdk5x3e	59	5	(	(	-LRB-
cord-002180-gsdk5x3e	59	6	mRNA	mrna	NN
cord-002180-gsdk5x3e	59	7	)	)	-RRB-
cord-002180-gsdk5x3e	59	8	transcripts	transcript	NNS
cord-002180-gsdk5x3e	59	9	were	be	VBD
cord-002180-gsdk5x3e	59	10	synthesized	synthesize	VBN
cord-002180-gsdk5x3e	59	11	from	from	IN
cord-002180-gsdk5x3e	59	12	the	the	DT
cord-002180-gsdk5x3e	59	13	linearized	linearize	VBN
cord-002180-gsdk5x3e	59	14	plasmids	plasmid	NNS
cord-002180-gsdk5x3e	59	15	using	use	VBG
cord-002180-gsdk5x3e	59	16	the	the	DT
cord-002180-gsdk5x3e	59	17	mMessage	mMessage	NNP
cord-002180-gsdk5x3e	59	18	mMachine	mMachine	NNP
cord-002180-gsdk5x3e	59	19	transcription	transcription	NN
cord-002180-gsdk5x3e	59	20	kit	kit	NN
cord-002180-gsdk5x3e	59	21	(	(	-LRB-
cord-002180-gsdk5x3e	59	22	Ambion	Ambion	NNP
cord-002180-gsdk5x3e	59	23	)	)	-RRB-
cord-002180-gsdk5x3e	59	24	and	and	CC
cord-002180-gsdk5x3e	59	25	purified	purify	VBN
cord-002180-gsdk5x3e	59	26	using	use	VBG
cord-002180-gsdk5x3e	59	27	MEGAclear	megaclear	NN
cord-002180-gsdk5x3e	59	28	transcription	transcription	NN
cord-002180-gsdk5x3e	59	29	clean	clean	VB
cord-002180-gsdk5x3e	59	30	-	-	HYPH
cord-002180-gsdk5x3e	59	31	up	up	RP
cord-002180-gsdk5x3e	59	32	kit	kit	NN
cord-002180-gsdk5x3e	59	33	(	(	-LRB-
cord-002180-gsdk5x3e	59	34	Ambion	Ambion	NNP
cord-002180-gsdk5x3e	59	35	)	)	-RRB-
cord-002180-gsdk5x3e	59	36	.	.	.
cord-002180-gsdk5x3e	60	1	Electroporation	electroporation	NN
cord-002180-gsdk5x3e	60	2	.	.	.
cord-002180-gsdk5x3e	61	1	Transfection	Transfection	NNP
cord-002180-gsdk5x3e	61	2	of	of	IN
cord-002180-gsdk5x3e	61	3	RNA	RNA	NNP
cord-002180-gsdk5x3e	61	4	transcripts	transcript	NNS
cord-002180-gsdk5x3e	61	5	was	be	VBD
cord-002180-gsdk5x3e	61	6	performed	perform	VBN
cord-002180-gsdk5x3e	61	7	using	use	VBG
cord-002180-gsdk5x3e	61	8	a	a	DT
cord-002180-gsdk5x3e	61	9	Neon	Neon	NNP
cord-002180-gsdk5x3e	61	10	Transfection	Transfection	NNP
cord-002180-gsdk5x3e	61	11	system	system	NN
cord-002180-gsdk5x3e	61	12	(	(	-LRB-
cord-002180-gsdk5x3e	61	13	Life	Life	NNP
cord-002180-gsdk5x3e	61	14	Technologies	Technologies	NNPS
cord-002180-gsdk5x3e	61	15	)	)	-RRB-
cord-002180-gsdk5x3e	61	16	,	,	,
cord-002180-gsdk5x3e	61	17	following	follow	VBG
cord-002180-gsdk5x3e	61	18	manufacturer	manufacturer	NN
cord-002180-gsdk5x3e	61	19	's	's	POS
cord-002180-gsdk5x3e	61	20	instructions	instruction	NNS
cord-002180-gsdk5x3e	61	21	.	.	.
cord-002180-gsdk5x3e	62	1	Briefly	briefly	RB
cord-002180-gsdk5x3e	62	2	,	,	,
cord-002180-gsdk5x3e	62	3	RAW	raw	JJ
cord-002180-gsdk5x3e	62	4	-	-	HYPH
cord-002180-gsdk5x3e	62	5	Blue	blue	JJ
cord-002180-gsdk5x3e	62	6	cells	cell	NNS
cord-002180-gsdk5x3e	62	7	were	be	VBD
cord-002180-gsdk5x3e	62	8	suspended	suspend	VBN
cord-002180-gsdk5x3e	62	9	in	in	IN
cord-002180-gsdk5x3e	62	10	resuspension	resuspension	NN
cord-002180-gsdk5x3e	62	11	buffer	buffer	NN
cord-002180-gsdk5x3e	62	12	and	and	CC
cord-002180-gsdk5x3e	62	13	approximately	approximately	RB
cord-002180-gsdk5x3e	62	14	1	1	CD
cord-002180-gsdk5x3e	62	15	×	×	CD
cord-002180-gsdk5x3e	62	16	10	10	CD
cord-002180-gsdk5x3e	62	17	6	6	CD
cord-002180-gsdk5x3e	62	18	cells	cell	NNS
cord-002180-gsdk5x3e	62	19	transfected	transfecte	VBN
cord-002180-gsdk5x3e	62	20	with	with	IN
cord-002180-gsdk5x3e	62	21	4	4	CD
cord-002180-gsdk5x3e	62	22	-	-	SYM
cord-002180-gsdk5x3e	62	23	6	6	CD
cord-002180-gsdk5x3e	62	24	μg	μg	NNP
cord-002180-gsdk5x3e	62	25	of	of	IN
cord-002180-gsdk5x3e	62	26	RNA	RNA	NNP
cord-002180-gsdk5x3e	62	27	using	use	VBG
cord-002180-gsdk5x3e	62	28	1	1	CD
cord-002180-gsdk5x3e	62	29	pulse	pulse	NN
cord-002180-gsdk5x3e	62	30	at	at	IN
cord-002180-gsdk5x3e	62	31	1730	1730	CD
cord-002180-gsdk5x3e	62	32	V	v	NN
cord-002180-gsdk5x3e	62	33	and	and	CC
cord-002180-gsdk5x3e	62	34	20	20	CD
cord-002180-gsdk5x3e	62	35	mA.	mA.	NNS
cord-002180-gsdk5x3e	62	36	Transfected	Transfected	NNP
cord-002180-gsdk5x3e	62	37	cells	cell	NNS
cord-002180-gsdk5x3e	62	38	were	be	VBD
cord-002180-gsdk5x3e	62	39	added	add	VBN
cord-002180-gsdk5x3e	62	40	to	to	IN
cord-002180-gsdk5x3e	62	41	2	2	CD
cord-002180-gsdk5x3e	62	42	ml	ml	NNS
cord-002180-gsdk5x3e	62	43	of	of	IN
cord-002180-gsdk5x3e	62	44	pre	pre	JJ
cord-002180-gsdk5x3e	62	45	-	-	JJ
cord-002180-gsdk5x3e	62	46	warmed	warm	VBN
cord-002180-gsdk5x3e	62	47	medium	medium	NN
cord-002180-gsdk5x3e	62	48	in	in	IN
cord-002180-gsdk5x3e	62	49	a	a	DT
cord-002180-gsdk5x3e	62	50	6-well	6-well	CD
cord-002180-gsdk5x3e	62	51	plate	plate	NN
cord-002180-gsdk5x3e	62	52	and	and	CC
cord-002180-gsdk5x3e	62	53	incubated	incubate	VBN
cord-002180-gsdk5x3e	62	54	for	for	IN
cord-002180-gsdk5x3e	62	55	the	the	DT
cord-002180-gsdk5x3e	62	56	times	time	NNS
cord-002180-gsdk5x3e	62	57	indicated	indicate	VBD
cord-002180-gsdk5x3e	62	58	.	.	.
cord-002180-gsdk5x3e	63	1	Western	western	JJ
cord-002180-gsdk5x3e	63	2	blot	blot	NN
cord-002180-gsdk5x3e	63	3	analysis	analysis	NN
cord-002180-gsdk5x3e	63	4	.	.	.
cord-002180-gsdk5x3e	64	1	Transfected	transfected	JJ
cord-002180-gsdk5x3e	64	2	cells	cell	NNS
cord-002180-gsdk5x3e	64	3	were	be	VBD
cord-002180-gsdk5x3e	64	4	collected	collect	VBN
cord-002180-gsdk5x3e	64	5	posttransfection	posttransfection	NN
cord-002180-gsdk5x3e	64	6	and	and	CC
cord-002180-gsdk5x3e	64	7	washed	wash	VBD
cord-002180-gsdk5x3e	64	8	twice	twice	RB
cord-002180-gsdk5x3e	64	9	in	in	IN
cord-002180-gsdk5x3e	64	10	Dulbecco	Dulbecco	NNP
cord-002180-gsdk5x3e	64	11	's	's	POS
cord-002180-gsdk5x3e	64	12	phosphate	phosphate	NN
cord-002180-gsdk5x3e	64	13	buffered	buffer	VBN
cord-002180-gsdk5x3e	64	14	saline	saline	NN
cord-002180-gsdk5x3e	64	15	(	(	-LRB-
cord-002180-gsdk5x3e	64	16	dPBS	dpbs	NN
cord-002180-gsdk5x3e	64	17	)	)	-RRB-
cord-002180-gsdk5x3e	64	18	.	.	.
cord-002180-gsdk5x3e	65	1	Cells	cell	NNS
cord-002180-gsdk5x3e	65	2	were	be	VBD
cord-002180-gsdk5x3e	65	3	lysed	lyse	VBN
cord-002180-gsdk5x3e	65	4	directly	directly	RB
cord-002180-gsdk5x3e	65	5	in	in	IN
cord-002180-gsdk5x3e	65	6	25	25	CD
cord-002180-gsdk5x3e	65	7	μl	μl	NN
cord-002180-gsdk5x3e	65	8	dPBS	dpbs	NN
cord-002180-gsdk5x3e	65	9	and	and	CC
cord-002180-gsdk5x3e	65	10	25	25	CD
cord-002180-gsdk5x3e	65	11	μl	μl	UH
cord-002180-gsdk5x3e	65	12	sample	sample	NN
cord-002180-gsdk5x3e	65	13	buffer	buffer	NN
cord-002180-gsdk5x3e	65	14	(	(	-LRB-
cord-002180-gsdk5x3e	65	15	120	120	CD
cord-002180-gsdk5x3e	65	16	mM	mm	CD
cord-002180-gsdk5x3e	65	17	Tris	Tris	NNP
cord-002180-gsdk5x3e	65	18	-	-	HYPH
cord-002180-gsdk5x3e	65	19	HCl	HCl	NNP
cord-002180-gsdk5x3e	65	20	[	[	-LRB-
cord-002180-gsdk5x3e	65	21	pH	pH	NNP
cord-002180-gsdk5x3e	65	22	6.8	6.8	CD
cord-002180-gsdk5x3e	65	23	]	]	-RRB-
cord-002180-gsdk5x3e	65	24	,	,	,
cord-002180-gsdk5x3e	65	25	5	5	CD
cord-002180-gsdk5x3e	65	26	%	%	NN
cord-002180-gsdk5x3e	65	27	SDS	SDS	NNP
cord-002180-gsdk5x3e	65	28	,	,	,
cord-002180-gsdk5x3e	65	29	10	10	CD
cord-002180-gsdk5x3e	65	30	%	%	NN
cord-002180-gsdk5x3e	65	31	2-mercaptoethanol	2-mercaptoethanol	CD
cord-002180-gsdk5x3e	65	32	,	,	,
cord-002180-gsdk5x3e	65	33	20	20	CD
cord-002180-gsdk5x3e	65	34	%	%	NN
cord-002180-gsdk5x3e	65	35	glycerol	glycerol	NN
cord-002180-gsdk5x3e	65	36	,	,	,
cord-002180-gsdk5x3e	65	37	0.01	0.01	CD
cord-002180-gsdk5x3e	65	38	%	%	NN
cord-002180-gsdk5x3e	65	39	bromophenol	bromophenol	NNP
cord-002180-gsdk5x3e	65	40	blue	blue	NNP
cord-002180-gsdk5x3e	65	41	)	)	-RRB-
cord-002180-gsdk5x3e	65	42	,	,	,
cord-002180-gsdk5x3e	65	43	boiled	boil	VBN
cord-002180-gsdk5x3e	65	44	for	for	IN
cord-002180-gsdk5x3e	65	45	10	10	CD
cord-002180-gsdk5x3e	65	46	minutes	minute	NNS
cord-002180-gsdk5x3e	65	47	and	and	CC
cord-002180-gsdk5x3e	65	48	separated	separate	VBN
cord-002180-gsdk5x3e	65	49	by	by	IN
cord-002180-gsdk5x3e	65	50	SDS	SDS	NNP
cord-002180-gsdk5x3e	65	51	-	-	HYPH
cord-002180-gsdk5x3e	65	52	PAGE	page	NN
cord-002180-gsdk5x3e	65	53	electrophoresis	electrophoresis	NN
cord-002180-gsdk5x3e	65	54	.	.	.
cord-002180-gsdk5x3e	66	1	Proteins	protein	NNS
cord-002180-gsdk5x3e	66	2	were	be	VBD
cord-002180-gsdk5x3e	66	3	transferred	transfer	VBN
cord-002180-gsdk5x3e	66	4	to	to	IN
cord-002180-gsdk5x3e	66	5	nitrocellulose	nitrocellulose	NN
cord-002180-gsdk5x3e	66	6	membranes	membrane	NNS
cord-002180-gsdk5x3e	66	7	(	(	-LRB-
cord-002180-gsdk5x3e	66	8	Amersham	Amersham	NNP
cord-002180-gsdk5x3e	66	9	Hybond	Hybond	NNP
cord-002180-gsdk5x3e	66	10	-	-	HYPH
cord-002180-gsdk5x3e	66	11	C	C	NNP
cord-002180-gsdk5x3e	66	12	Extra	Extra	NNP
cord-002180-gsdk5x3e	66	13	;	;	:
cord-002180-gsdk5x3e	66	14	GE	GE	NNP
cord-002180-gsdk5x3e	66	15	Healthcare	Healthcare	NNP
cord-002180-gsdk5x3e	66	16	)	)	-RRB-
cord-002180-gsdk5x3e	66	17	and	and	CC
cord-002180-gsdk5x3e	66	18	detected	detect	VBD
cord-002180-gsdk5x3e	66	19	with	with	IN
cord-002180-gsdk5x3e	66	20	the	the	DT
cord-002180-gsdk5x3e	66	21	corresponding	corresponding	JJ
cord-002180-gsdk5x3e	66	22	primary	primary	JJ
cord-002180-gsdk5x3e	66	23	and	and	CC
cord-002180-gsdk5x3e	66	24	secondary	secondary	JJ
cord-002180-gsdk5x3e	66	25	antibodies	antibody	NNS
cord-002180-gsdk5x3e	66	26	.	.	.
cord-002180-gsdk5x3e	67	1	The	the	DT
cord-002180-gsdk5x3e	67	2	following	follow	VBG
cord-002180-gsdk5x3e	67	3	primary	primary	JJ
cord-002180-gsdk5x3e	67	4	antibodies	antibody	NNS
cord-002180-gsdk5x3e	67	5	were	be	VBD
cord-002180-gsdk5x3e	67	6	used	use	VBN
cord-002180-gsdk5x3e	67	7	;	;	:
cord-002180-gsdk5x3e	67	8	cyclin	cyclin	VB
cord-002180-gsdk5x3e	67	9	A	a	DT
cord-002180-gsdk5x3e	67	10	(	(	-LRB-
cord-002180-gsdk5x3e	67	11	H-432	h-432	NN
cord-002180-gsdk5x3e	67	12	)	)	-RRB-
cord-002180-gsdk5x3e	67	13	(	(	-LRB-
cord-002180-gsdk5x3e	67	14	sc-751	sc-751	NNP
cord-002180-gsdk5x3e	67	15	;	;	:
cord-002180-gsdk5x3e	67	16	Santa	Santa	NNP
cord-002180-gsdk5x3e	67	17	Cruz	Cruz	NNP
cord-002180-gsdk5x3e	67	18	)	)	-RRB-
cord-002180-gsdk5x3e	67	19	,	,	,
cord-002180-gsdk5x3e	67	20	actin	actin	NNP
cord-002180-gsdk5x3e	67	21	(	(	-LRB-
cord-002180-gsdk5x3e	68	1	I-19	I-19	NNP
cord-002180-gsdk5x3e	68	2	)	)	-RRB-
cord-002180-gsdk5x3e	68	3	(	(	-LRB-
cord-002180-gsdk5x3e	68	4	sc-1616	sc-1616	ADD
cord-002180-gsdk5x3e	68	5	;	;	:
cord-002180-gsdk5x3e	68	6	Santa	Santa	NNP
cord-002180-gsdk5x3e	68	7	Cruz	Cruz	NNP
cord-002180-gsdk5x3e	68	8	)	)	-RRB-
cord-002180-gsdk5x3e	68	9	,	,	,
cord-002180-gsdk5x3e	68	10	GFP	GFP	NNP
cord-002180-gsdk5x3e	68	11	(	(	-LRB-
cord-002180-gsdk5x3e	68	12	ab6556	ab6556	NNP
cord-002180-gsdk5x3e	68	13	;	;	:
cord-002180-gsdk5x3e	68	14	Abcam	Abcam	NNP
cord-002180-gsdk5x3e	68	15	)	)	-RRB-
cord-002180-gsdk5x3e	68	16	,	,	,
cord-002180-gsdk5x3e	68	17	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	68	18	anti	anti	JJ
cord-002180-gsdk5x3e	68	19	-	-	JJ
cord-002180-gsdk5x3e	68	20	NS1	ns1	JJ
cord-002180-gsdk5x3e	68	21	-	-	HYPH
cord-002180-gsdk5x3e	68	22	2	2	CD
cord-002180-gsdk5x3e	68	23	[	[	-LRB-
cord-002180-gsdk5x3e	68	24	13	13	CD
cord-002180-gsdk5x3e	68	25	]	]	-RRB-
cord-002180-gsdk5x3e	68	26	and	and	CC
cord-002180-gsdk5x3e	68	27	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	68	28	anti	anti	JJ
cord-002180-gsdk5x3e	68	29	-	-	JJ
cord-002180-gsdk5x3e	68	30	NS5	ns5	JJ
cord-002180-gsdk5x3e	68	31	[	[	-LRB-
cord-002180-gsdk5x3e	68	32	13	13	CD
cord-002180-gsdk5x3e	68	33	]	]	-RRB-
cord-002180-gsdk5x3e	68	34	.	.	.
cord-002180-gsdk5x3e	69	1	Secondary	secondary	JJ
cord-002180-gsdk5x3e	69	2	antibodies	antibody	NNS
cord-002180-gsdk5x3e	69	3	used	use	VBD
cord-002180-gsdk5x3e	69	4	were	be	VBD
cord-002180-gsdk5x3e	69	5	680RD	680RD	NNP
cord-002180-gsdk5x3e	69	6	donkey	donkey	NN
cord-002180-gsdk5x3e	69	7	anti	anti	JJ
cord-002180-gsdk5x3e	69	8	-	-	JJ
cord-002180-gsdk5x3e	69	9	goat	goat	JJ
cord-002180-gsdk5x3e	69	10	IgG	igg	NN
cord-002180-gsdk5x3e	69	11	(	(	-LRB-
cord-002180-gsdk5x3e	69	12	926	926	CD
cord-002180-gsdk5x3e	69	13	-	-	HYPH
cord-002180-gsdk5x3e	69	14	68074	68074	CD
cord-002180-gsdk5x3e	69	15	;	;	:
cord-002180-gsdk5x3e	69	16	LI	LI	NNP
cord-002180-gsdk5x3e	69	17	-	-	HYPH
cord-002180-gsdk5x3e	69	18	COR	COR	NNP
cord-002180-gsdk5x3e	69	19	)	)	-RRB-
cord-002180-gsdk5x3e	69	20	and	and	CC
cord-002180-gsdk5x3e	69	21	800CW	800CW	NNP
cord-002180-gsdk5x3e	69	22	donkey	donkey	NN
cord-002180-gsdk5x3e	69	23	anti	anti	JJ
cord-002180-gsdk5x3e	69	24	-	-	JJ
cord-002180-gsdk5x3e	69	25	rabbit	rabbit	JJ
cord-002180-gsdk5x3e	69	26	IgG	igg	NN
cord-002180-gsdk5x3e	69	27	(	(	-LRB-
cord-002180-gsdk5x3e	69	28	926	926	CD
cord-002180-gsdk5x3e	69	29	-	-	HYPH
cord-002180-gsdk5x3e	69	30	32213	32213	CD
cord-002180-gsdk5x3e	69	31	;	;	:
cord-002180-gsdk5x3e	69	32	LI	LI	NNP
cord-002180-gsdk5x3e	69	33	-	-	HYPH
cord-002180-gsdk5x3e	69	34	COR	COR	NNP
cord-002180-gsdk5x3e	69	35	)	)	-RRB-
cord-002180-gsdk5x3e	69	36	.	.	.
cord-002180-gsdk5x3e	70	1	Synchronization	synchronization	NN
cord-002180-gsdk5x3e	70	2	of	of	IN
cord-002180-gsdk5x3e	70	3	cells	cell	NNS
cord-002180-gsdk5x3e	70	4	.	.	.
cord-002180-gsdk5x3e	71	1	To	to	TO
cord-002180-gsdk5x3e	71	2	synchronize	synchronize	VB
cord-002180-gsdk5x3e	71	3	cells	cell	NNS
cord-002180-gsdk5x3e	71	4	to	to	IN
cord-002180-gsdk5x3e	71	5	the	the	DT
cord-002180-gsdk5x3e	71	6	G	g	NN
cord-002180-gsdk5x3e	71	7	1	1	CD
cord-002180-gsdk5x3e	71	8	phase	phase	NN
cord-002180-gsdk5x3e	71	9	,	,	,
cord-002180-gsdk5x3e	71	10	approximately	approximately	RB
cord-002180-gsdk5x3e	71	11	2	2	CD
cord-002180-gsdk5x3e	71	12	×	×	NN
cord-002180-gsdk5x3e	71	13	10	10	CD
cord-002180-gsdk5x3e	71	14	6	6	CD
cord-002180-gsdk5x3e	71	15	cells	cell	NNS
cord-002180-gsdk5x3e	71	16	were	be	VBD
cord-002180-gsdk5x3e	71	17	seeded	seed	VBN
cord-002180-gsdk5x3e	71	18	in	in	IN
cord-002180-gsdk5x3e	71	19	25-cm	25-cm	CD
cord-002180-gsdk5x3e	71	20	2	2	CD
cord-002180-gsdk5x3e	71	21	flasks	flask	NNS
cord-002180-gsdk5x3e	71	22	and	and	CC
cord-002180-gsdk5x3e	71	23	treated	treat	VBN
cord-002180-gsdk5x3e	71	24	with	with	IN
cord-002180-gsdk5x3e	71	25	3	3	CD
cord-002180-gsdk5x3e	71	26	mM	mm	CD
cord-002180-gsdk5x3e	71	27	sodium	sodium	NN
cord-002180-gsdk5x3e	71	28	butyrate	butyrate	NN
cord-002180-gsdk5x3e	71	29	(	(	-LRB-
cord-002180-gsdk5x3e	71	30	N	n	NN
cord-002180-gsdk5x3e	71	31	-	-	HYPH
cord-002180-gsdk5x3e	71	32	butyrate	butyrate	NN
cord-002180-gsdk5x3e	71	33	)	)	-RRB-
cord-002180-gsdk5x3e	72	1	(	(	-LRB-
cord-002180-gsdk5x3e	72	2	B5887	B5887	NNP
cord-002180-gsdk5x3e	72	3	;	;	:
cord-002180-gsdk5x3e	72	4	Sigma	Sigma	NNP
cord-002180-gsdk5x3e	72	5	)	)	-RRB-
cord-002180-gsdk5x3e	73	1	for	for	IN
cord-002180-gsdk5x3e	73	2	20	20	CD
cord-002180-gsdk5x3e	73	3	h	h	NN
cord-002180-gsdk5x3e	73	4	[	[	-LRB-
cord-002180-gsdk5x3e	73	5	28	28	CD
cord-002180-gsdk5x3e	73	6	,	,	,
cord-002180-gsdk5x3e	73	7	29	29	CD
cord-002180-gsdk5x3e	73	8	]	]	-RRB-
cord-002180-gsdk5x3e	73	9	.	.	.
cord-002180-gsdk5x3e	74	1	Cell	cell	NN
cord-002180-gsdk5x3e	74	2	cycle	cycle	NN
cord-002180-gsdk5x3e	74	3	analysis	analysis	NN
cord-002180-gsdk5x3e	74	4	by	by	IN
cord-002180-gsdk5x3e	74	5	flow	flow	NN
cord-002180-gsdk5x3e	74	6	cytometry	cytometry	NN
cord-002180-gsdk5x3e	74	7	.	.	.
cord-002180-gsdk5x3e	75	1	Nuclear	nuclear	JJ
cord-002180-gsdk5x3e	75	2	DNA	dna	NN
cord-002180-gsdk5x3e	75	3	content	content	NN
cord-002180-gsdk5x3e	75	4	was	be	VBD
cord-002180-gsdk5x3e	75	5	measured	measure	VBN
cord-002180-gsdk5x3e	75	6	by	by	IN
cord-002180-gsdk5x3e	75	7	propidium	propidium	NN
cord-002180-gsdk5x3e	75	8	iodide	iodide	NN
cord-002180-gsdk5x3e	75	9	staining	staining	NN
cord-002180-gsdk5x3e	75	10	and	and	CC
cord-002180-gsdk5x3e	75	11	fluorescence	fluorescence	NN
cord-002180-gsdk5x3e	75	12	-	-	HYPH
cord-002180-gsdk5x3e	75	13	activated	activate	VBN
cord-002180-gsdk5x3e	75	14	cell	cell	NN
cord-002180-gsdk5x3e	75	15	sorting	sorting	NN
cord-002180-gsdk5x3e	75	16	(	(	-LRB-
cord-002180-gsdk5x3e	75	17	FACS	FACS	NNP
cord-002180-gsdk5x3e	75	18	)	)	-RRB-
cord-002180-gsdk5x3e	75	19	as	as	IN
cord-002180-gsdk5x3e	75	20	previously	previously	RB
cord-002180-gsdk5x3e	75	21	described	describe	VBN
cord-002180-gsdk5x3e	75	22	[	[	-LRB-
cord-002180-gsdk5x3e	75	23	20	20	CD
cord-002180-gsdk5x3e	75	24	]	]	-RRB-
cord-002180-gsdk5x3e	75	25	.	.	.
cord-002180-gsdk5x3e	76	1	Briefly	briefly	RB
cord-002180-gsdk5x3e	76	2	,	,	,
cord-002180-gsdk5x3e	76	3	cells	cell	NNS
cord-002180-gsdk5x3e	76	4	were	be	VBD
cord-002180-gsdk5x3e	76	5	scraped	scrape	VBN
cord-002180-gsdk5x3e	76	6	,	,	,
cord-002180-gsdk5x3e	76	7	washed	wash	VBN
cord-002180-gsdk5x3e	76	8	in	in	IN
cord-002180-gsdk5x3e	76	9	dPBS	dpbs	NN
cord-002180-gsdk5x3e	76	10	and	and	CC
cord-002180-gsdk5x3e	76	11	fixed	fix	VBN
cord-002180-gsdk5x3e	76	12	in	in	IN
cord-002180-gsdk5x3e	76	13	3	3	CD
cord-002180-gsdk5x3e	76	14	ml	ml	NNS
cord-002180-gsdk5x3e	76	15	of	of	IN
cord-002180-gsdk5x3e	76	16	cold	cold	JJ
cord-002180-gsdk5x3e	76	17	70	70	CD
cord-002180-gsdk5x3e	76	18	%	%	NN
cord-002180-gsdk5x3e	76	19	absolute	absolute	JJ
cord-002180-gsdk5x3e	76	20	ethanol	ethanol	NN
cord-002180-gsdk5x3e	76	21	overnight	overnight	RB
cord-002180-gsdk5x3e	76	22	.	.	.
cord-002180-gsdk5x3e	77	1	Fixed	fix	VBN
cord-002180-gsdk5x3e	77	2	cells	cell	NNS
cord-002180-gsdk5x3e	77	3	were	be	VBD
cord-002180-gsdk5x3e	77	4	washed	wash	VBN
cord-002180-gsdk5x3e	77	5	in	in	IN
cord-002180-gsdk5x3e	77	6	dPBS	dpbs	NN
cord-002180-gsdk5x3e	77	7	and	and	CC
cord-002180-gsdk5x3e	77	8	stained	stain	VBN
cord-002180-gsdk5x3e	77	9	in	in	IN
cord-002180-gsdk5x3e	77	10	50	50	CD
cord-002180-gsdk5x3e	77	11	μg	μg	NNP
cord-002180-gsdk5x3e	77	12	/	/	SYM
cord-002180-gsdk5x3e	77	13	ml	ml	NN
cord-002180-gsdk5x3e	77	14	propidium	propidium	NN
cord-002180-gsdk5x3e	77	15	iodide	iodide	NN
cord-002180-gsdk5x3e	77	16	(	(	-LRB-
cord-002180-gsdk5x3e	77	17	P4170	P4170	NNP
cord-002180-gsdk5x3e	77	18	;	;	:
cord-002180-gsdk5x3e	77	19	Sigma	Sigma	NNP
cord-002180-gsdk5x3e	77	20	)	)	-RRB-
cord-002180-gsdk5x3e	77	21	and	and	CC
cord-002180-gsdk5x3e	78	1	0.1	0.1	CD
cord-002180-gsdk5x3e	78	2	mg	mg	NNP
cord-002180-gsdk5x3e	78	3	/	/	SYM
cord-002180-gsdk5x3e	78	4	ml	ml	NN
cord-002180-gsdk5x3e	79	1	RNase	RNase	NNP
cord-002180-gsdk5x3e	79	2	A	A	NNP
cord-002180-gsdk5x3e	79	3	(	(	-LRB-
cord-002180-gsdk5x3e	79	4	R4875	R4875	NNP
cord-002180-gsdk5x3e	79	5	;	;	:
cord-002180-gsdk5x3e	79	6	Sigma	Sigma	NNP
cord-002180-gsdk5x3e	79	7	)	)	-RRB-
cord-002180-gsdk5x3e	79	8	for	for	IN
cord-002180-gsdk5x3e	79	9	45	45	CD
cord-002180-gsdk5x3e	79	10	min	min	NN
cord-002180-gsdk5x3e	79	11	at	at	IN
cord-002180-gsdk5x3e	79	12	37	37	CD
cord-002180-gsdk5x3e	79	13	°	°	NN
cord-002180-gsdk5x3e	79	14	C	c	NN
cord-002180-gsdk5x3e	79	15	in	in	IN
cord-002180-gsdk5x3e	79	16	5	5	CD
cord-002180-gsdk5x3e	79	17	%	%	NN
cord-002180-gsdk5x3e	79	18	CO	co	NN
cord-002180-gsdk5x3e	79	19	2	2	CD
cord-002180-gsdk5x3e	79	20	.	.	.
cord-002180-gsdk5x3e	80	1	Stained	stained	JJ
cord-002180-gsdk5x3e	80	2	cells	cell	NNS
cord-002180-gsdk5x3e	80	3	were	be	VBD
cord-002180-gsdk5x3e	80	4	washed	wash	VBN
cord-002180-gsdk5x3e	80	5	and	and	CC
cord-002180-gsdk5x3e	80	6	analyzed	analyze	VBN
cord-002180-gsdk5x3e	80	7	using	use	VBG
cord-002180-gsdk5x3e	80	8	fluorescence	fluorescence	NN
cord-002180-gsdk5x3e	80	9	-	-	HYPH
cord-002180-gsdk5x3e	80	10	activated	activate	VBN
cord-002180-gsdk5x3e	80	11	cell	cell	NN
cord-002180-gsdk5x3e	80	12	sorting	sorting	NN
cord-002180-gsdk5x3e	80	13	(	(	-LRB-
cord-002180-gsdk5x3e	80	14	FACS	FACS	NNP
cord-002180-gsdk5x3e	80	15	)	)	-RRB-
cord-002180-gsdk5x3e	80	16	;	;	:
cord-002180-gsdk5x3e	80	17	data	datum	NNS
cord-002180-gsdk5x3e	80	18	was	be	VBD
cord-002180-gsdk5x3e	80	19	analyzed	analyze	VBN
cord-002180-gsdk5x3e	80	20	with	with	IN
cord-002180-gsdk5x3e	80	21	MODfit	MODfit	NNP
cord-002180-gsdk5x3e	80	22	LT	LT	NNP
cord-002180-gsdk5x3e	80	23	3.0	3.0	CD
cord-002180-gsdk5x3e	80	24	software	software	NN
cord-002180-gsdk5x3e	80	25	(	(	-LRB-
cord-002180-gsdk5x3e	80	26	Verity	Verity	NNP
cord-002180-gsdk5x3e	80	27	Software	Software	NNP
cord-002180-gsdk5x3e	80	28	House	House	NNP
cord-002180-gsdk5x3e	80	29	)	)	-RRB-
cord-002180-gsdk5x3e	80	30	.	.	.
cord-002180-gsdk5x3e	81	1	Statistical	statistical	JJ
cord-002180-gsdk5x3e	81	2	and	and	CC
cord-002180-gsdk5x3e	81	3	densitometric	densitometric	JJ
cord-002180-gsdk5x3e	81	4	analyses	analysis	NNS
cord-002180-gsdk5x3e	81	5	.	.	.
cord-002180-gsdk5x3e	82	1	Data	Data	NNP
cord-002180-gsdk5x3e	82	2	is	be	VBZ
cord-002180-gsdk5x3e	82	3	presented	present	VBN
cord-002180-gsdk5x3e	82	4	as	as	IN
cord-002180-gsdk5x3e	82	5	means	mean	NNS
cord-002180-gsdk5x3e	82	6	and	and	CC
cord-002180-gsdk5x3e	82	7	standard	standard	JJ
cord-002180-gsdk5x3e	82	8	deviations	deviation	NNS
cord-002180-gsdk5x3e	82	9	(	(	-LRB-
cord-002180-gsdk5x3e	82	10	SD	SD	NNP
cord-002180-gsdk5x3e	82	11	)	)	-RRB-
cord-002180-gsdk5x3e	82	12	.	.	.
cord-002180-gsdk5x3e	83	1	Results	result	NNS
cord-002180-gsdk5x3e	83	2	were	be	VBD
cord-002180-gsdk5x3e	83	3	analyzed	analyze	VBN
cord-002180-gsdk5x3e	83	4	with	with	IN
cord-002180-gsdk5x3e	83	5	either	either	CC
cord-002180-gsdk5x3e	83	6	a	a	DT
cord-002180-gsdk5x3e	83	7	Student	Student	NNP
cord-002180-gsdk5x3e	83	8	's	's	POS
cord-002180-gsdk5x3e	83	9	t	t	NN
cord-002180-gsdk5x3e	83	10	-	-	HYPH
cord-002180-gsdk5x3e	83	11	test	test	NN
cord-002180-gsdk5x3e	83	12	or	or	CC
cord-002180-gsdk5x3e	83	13	a	a	DT
cord-002180-gsdk5x3e	83	14	one	one	CD
cord-002180-gsdk5x3e	83	15	-	-	HYPH
cord-002180-gsdk5x3e	83	16	way	way	NN
cord-002180-gsdk5x3e	83	17	ANOVA	anova	NN
cord-002180-gsdk5x3e	83	18	with	with	IN
cord-002180-gsdk5x3e	83	19	the	the	DT
cord-002180-gsdk5x3e	83	20	appropriate	appropriate	JJ
cord-002180-gsdk5x3e	83	21	post	post	NN
cord-002180-gsdk5x3e	83	22	-	-	JJ
cord-002180-gsdk5x3e	83	23	test	test	NN
cord-002180-gsdk5x3e	83	24	as	as	IN
cord-002180-gsdk5x3e	83	25	stated	state	VBN
cord-002180-gsdk5x3e	83	26	.	.	.
cord-002180-gsdk5x3e	84	1	P	p	NN
cord-002180-gsdk5x3e	84	2	values	value	NNS
cord-002180-gsdk5x3e	84	3	of	of	IN
cord-002180-gsdk5x3e	84	4	0.05	0.05	CD
cord-002180-gsdk5x3e	84	5	were	be	VBD
cord-002180-gsdk5x3e	84	6	considered	consider	VBN
cord-002180-gsdk5x3e	84	7	statistically	statistically	RB
cord-002180-gsdk5x3e	84	8	significant	significant	JJ
cord-002180-gsdk5x3e	84	9	.	.	.
cord-002180-gsdk5x3e	85	1	Western	western	JJ
cord-002180-gsdk5x3e	85	2	blots	blot	NNS
cord-002180-gsdk5x3e	85	3	are	be	VBP
cord-002180-gsdk5x3e	85	4	shown	show	VBN
cord-002180-gsdk5x3e	85	5	for	for	IN
cord-002180-gsdk5x3e	85	6	one	one	CD
cord-002180-gsdk5x3e	85	7	of	of	IN
cord-002180-gsdk5x3e	85	8	three	three	CD
cord-002180-gsdk5x3e	85	9	independent	independent	JJ
cord-002180-gsdk5x3e	85	10	experiments	experiment	NNS
cord-002180-gsdk5x3e	85	11	.	.	.
cord-002180-gsdk5x3e	86	1	Band	band	NN
cord-002180-gsdk5x3e	86	2	analysis	analysis	NN
cord-002180-gsdk5x3e	86	3	for	for	IN
cord-002180-gsdk5x3e	86	4	each	each	DT
cord-002180-gsdk5x3e	86	5	protein	protein	NN
cord-002180-gsdk5x3e	86	6	was	be	VBD
cord-002180-gsdk5x3e	86	7	quantified	quantify	VBN
cord-002180-gsdk5x3e	86	8	using	use	VBG
cord-002180-gsdk5x3e	86	9	Image	Image	NNP
cord-002180-gsdk5x3e	86	10	Studio	Studio	NNP
cord-002180-gsdk5x3e	86	11	Lite	Lite	NNP
cord-002180-gsdk5x3e	86	12	software	software	NN
cord-002180-gsdk5x3e	86	13	.	.	.
cord-002180-gsdk5x3e	87	1	Each	each	DT
cord-002180-gsdk5x3e	87	2	protein	protein	NN
cord-002180-gsdk5x3e	87	3	quantification	quantification	NN
cord-002180-gsdk5x3e	87	4	was	be	VBD
cord-002180-gsdk5x3e	87	5	first	first	RB
cord-002180-gsdk5x3e	87	6	normalized	normalize	VBN
cord-002180-gsdk5x3e	87	7	against	against	IN
cord-002180-gsdk5x3e	87	8	actin	actin	NN
cord-002180-gsdk5x3e	87	9	loading	loading	NN
cord-002180-gsdk5x3e	87	10	before	before	IN
cord-002180-gsdk5x3e	87	11	comparisons	comparison	NNS
cord-002180-gsdk5x3e	87	12	for	for	IN
cord-002180-gsdk5x3e	87	13	changes	change	NNS
cord-002180-gsdk5x3e	87	14	(	(	-LRB-
cord-002180-gsdk5x3e	87	15	recorded	record	VBN
cord-002180-gsdk5x3e	87	16	as	as	IN
cord-002180-gsdk5x3e	87	17	a	a	DT
cord-002180-gsdk5x3e	87	18	percentage	percentage	NN
cord-002180-gsdk5x3e	87	19	of	of	IN
cord-002180-gsdk5x3e	87	20	mocktransfected	mocktransfecte	VBN
cord-002180-gsdk5x3e	87	21	)	)	-RRB-
cord-002180-gsdk5x3e	87	22	were	be	VBD
cord-002180-gsdk5x3e	87	23	made	make	VBN
cord-002180-gsdk5x3e	87	24	.	.	.
cord-002180-gsdk5x3e	88	1	Expression	expression	NN
cord-002180-gsdk5x3e	88	2	of	of	IN
cord-002180-gsdk5x3e	88	3	NS5	NS5	NNP
cord-002180-gsdk5x3e	88	4	induces	induce	VBZ
cord-002180-gsdk5x3e	88	5	a	a	DT
cord-002180-gsdk5x3e	88	6	G	g	NN
cord-002180-gsdk5x3e	88	7	0	0	CD
cord-002180-gsdk5x3e	88	8	/G	/g	SYM
cord-002180-gsdk5x3e	88	9	1	1	CD
cord-002180-gsdk5x3e	88	10	phase	phase	NN
cord-002180-gsdk5x3e	88	11	arrest	arrest	NN
cord-002180-gsdk5x3e	88	12	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	88	13	infection	infection	NN
cord-002180-gsdk5x3e	88	14	of	of	IN
cord-002180-gsdk5x3e	88	15	RAW	raw	JJ
cord-002180-gsdk5x3e	88	16	-	-	HYPH
cord-002180-gsdk5x3e	88	17	Blue	blue	JJ
cord-002180-gsdk5x3e	88	18	cells	cell	NNS
cord-002180-gsdk5x3e	88	19	induces	induce	VBZ
cord-002180-gsdk5x3e	88	20	an	an	DT
cord-002180-gsdk5x3e	88	21	arrest	arrest	NN
cord-002180-gsdk5x3e	88	22	at	at	IN
cord-002180-gsdk5x3e	88	23	the	the	DT
cord-002180-gsdk5x3e	88	24	G	g	NN
cord-002180-gsdk5x3e	88	25	1	1	CD
cord-002180-gsdk5x3e	88	26	/S	/S	NNP
cord-002180-gsdk5x3e	88	27	restriction	restriction	NN
cord-002180-gsdk5x3e	88	28	point	point	NN
cord-002180-gsdk5x3e	88	29	,	,	,
cord-002180-gsdk5x3e	88	30	increasing	increase	VBG
cord-002180-gsdk5x3e	88	31	the	the	DT
cord-002180-gsdk5x3e	88	32	G	g	NN
cord-002180-gsdk5x3e	88	33	0	0	CD
cord-002180-gsdk5x3e	88	34	/G	/g	SYM
cord-002180-gsdk5x3e	88	35	1	1	CD
cord-002180-gsdk5x3e	88	36	population	population	NN
cord-002180-gsdk5x3e	88	37	in	in	IN
cord-002180-gsdk5x3e	88	38	order	order	NN
cord-002180-gsdk5x3e	88	39	to	to	TO
cord-002180-gsdk5x3e	88	40	change	change	VB
cord-002180-gsdk5x3e	88	41	the	the	DT
cord-002180-gsdk5x3e	88	42	internal	internal	JJ
cord-002180-gsdk5x3e	88	43	cellular	cellular	JJ
cord-002180-gsdk5x3e	88	44	environment	environment	NN
cord-002180-gsdk5x3e	88	45	to	to	TO
cord-002180-gsdk5x3e	88	46	favor	favor	VB
cord-002180-gsdk5x3e	88	47	viral	viral	JJ
cord-002180-gsdk5x3e	88	48	replication	replication	NN
cord-002180-gsdk5x3e	88	49	[	[	-LRB-
cord-002180-gsdk5x3e	88	50	20	20	CD
cord-002180-gsdk5x3e	88	51	]	]	-RRB-
cord-002180-gsdk5x3e	88	52	.	.	.
cord-002180-gsdk5x3e	89	1	We	-PRON-	PRP
cord-002180-gsdk5x3e	89	2	sought	seek	VBD
cord-002180-gsdk5x3e	89	3	to	to	TO
cord-002180-gsdk5x3e	89	4	determine	determine	VB
cord-002180-gsdk5x3e	89	5	if	if	IN
cord-002180-gsdk5x3e	89	6	a	a	DT
cord-002180-gsdk5x3e	89	7	viral	viral	JJ
cord-002180-gsdk5x3e	89	8	encoded	encode	VBN
cord-002180-gsdk5x3e	89	9	protein	protein	NN
cord-002180-gsdk5x3e	89	10	was	be	VBD
cord-002180-gsdk5x3e	89	11	responsible	responsible	JJ
cord-002180-gsdk5x3e	89	12	by	by	IN
cord-002180-gsdk5x3e	89	13	analysis	analysis	NN
cord-002180-gsdk5x3e	89	14	of	of	IN
cord-002180-gsdk5x3e	89	15	the	the	DT
cord-002180-gsdk5x3e	89	16	non	non	JJ
cord-002180-gsdk5x3e	89	17	-	-	JJ
cord-002180-gsdk5x3e	89	18	structural	structural	JJ
cord-002180-gsdk5x3e	89	19	proteins	protein	NNS
cord-002180-gsdk5x3e	89	20	of	of	IN
cord-002180-gsdk5x3e	89	21	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	89	22	for	for	IN
cord-002180-gsdk5x3e	89	23	effects	effect	NNS
cord-002180-gsdk5x3e	89	24	to	to	IN
cord-002180-gsdk5x3e	89	25	the	the	DT
cord-002180-gsdk5x3e	89	26	host	host	NN
cord-002180-gsdk5x3e	89	27	cell	cell	NN
cord-002180-gsdk5x3e	89	28	cycle	cycle	NN
cord-002180-gsdk5x3e	89	29	.	.	.
cord-002180-gsdk5x3e	90	1	The	the	DT
cord-002180-gsdk5x3e	90	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	90	3	protein	protein	NN
cord-002180-gsdk5x3e	90	4	from	from	IN
cord-002180-gsdk5x3e	90	5	caliciviruses	caliciviruse	NNS
cord-002180-gsdk5x3e	90	6	is	be	VBZ
cord-002180-gsdk5x3e	90	7	essential	essential	JJ
cord-002180-gsdk5x3e	90	8	to	to	IN
cord-002180-gsdk5x3e	90	9	viral	viral	JJ
cord-002180-gsdk5x3e	90	10	RNA	RNA	NNP
cord-002180-gsdk5x3e	90	11	transcription	transcription	NN
cord-002180-gsdk5x3e	90	12	and	and	CC
cord-002180-gsdk5x3e	90	13	translation	translation	NN
cord-002180-gsdk5x3e	90	14	and	and	CC
cord-002180-gsdk5x3e	90	15	is	be	VBZ
cord-002180-gsdk5x3e	90	16	essential	essential	JJ
cord-002180-gsdk5x3e	90	17	for	for	IN
cord-002180-gsdk5x3e	90	18	calicivirus	calicivirus	JJ
cord-002180-gsdk5x3e	90	19	replication	replication	NN
cord-002180-gsdk5x3e	90	20	.	.	.
cord-002180-gsdk5x3e	91	1	The	the	DT
cord-002180-gsdk5x3e	91	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	91	3	protein	protein	NN
cord-002180-gsdk5x3e	91	4	has	have	VBZ
cord-002180-gsdk5x3e	91	5	been	be	VBN
cord-002180-gsdk5x3e	91	6	shown	show	VBN
cord-002180-gsdk5x3e	91	7	to	to	TO
cord-002180-gsdk5x3e	91	8	bind	bind	VB
cord-002180-gsdk5x3e	91	9	host	host	NN
cord-002180-gsdk5x3e	91	10	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	91	11	translation	translation	NN
cord-002180-gsdk5x3e	91	12	initiation	initiation	NN
cord-002180-gsdk5x3e	91	13	factors	factor	NNS
cord-002180-gsdk5x3e	91	14	,	,	,
cord-002180-gsdk5x3e	91	15	recruiting	recruit	VBG
cord-002180-gsdk5x3e	91	16	these	these	DT
cord-002180-gsdk5x3e	91	17	proteins	protein	NNS
cord-002180-gsdk5x3e	91	18	for	for	IN
cord-002180-gsdk5x3e	91	19	preferential	preferential	JJ
cord-002180-gsdk5x3e	91	20	viral	viral	JJ
cord-002180-gsdk5x3e	91	21	translation	translation	NN
cord-002180-gsdk5x3e	91	22	and	and	CC
cord-002180-gsdk5x3e	91	23	potentially	potentially	RB
cord-002180-gsdk5x3e	91	24	inhibiting	inhibit	VBG
cord-002180-gsdk5x3e	91	25	host	host	NN
cord-002180-gsdk5x3e	91	26	protein	protein	NN
cord-002180-gsdk5x3e	91	27	expression	expression	NN
cord-002180-gsdk5x3e	91	28	[	[	-LRB-
cord-002180-gsdk5x3e	91	29	11	11	CD
cord-002180-gsdk5x3e	91	30	,	,	,
cord-002180-gsdk5x3e	91	31	30	30	CD
cord-002180-gsdk5x3e	91	32	]	]	-RRB-
cord-002180-gsdk5x3e	91	33	.	.	.
cord-002180-gsdk5x3e	92	1	We	-PRON-	PRP
cord-002180-gsdk5x3e	92	2	hypothesized	hypothesize	VBD
cord-002180-gsdk5x3e	92	3	that	that	IN
cord-002180-gsdk5x3e	92	4	an	an	DT
cord-002180-gsdk5x3e	92	5	inhibition	inhibition	NN
cord-002180-gsdk5x3e	92	6	of	of	IN
cord-002180-gsdk5x3e	92	7	host	host	NN
cord-002180-gsdk5x3e	92	8	protein	protein	NN
cord-002180-gsdk5x3e	92	9	expression	expression	NN
cord-002180-gsdk5x3e	92	10	may	may	MD
cord-002180-gsdk5x3e	92	11	contribute	contribute	VB
cord-002180-gsdk5x3e	92	12	to	to	IN
cord-002180-gsdk5x3e	92	13	a	a	DT
cord-002180-gsdk5x3e	92	14	cell	cell	NN
cord-002180-gsdk5x3e	92	15	cycle	cycle	NN
cord-002180-gsdk5x3e	92	16	arrest	arrest	NN
cord-002180-gsdk5x3e	92	17	.	.	.
cord-002180-gsdk5x3e	93	1	The	the	DT
cord-002180-gsdk5x3e	93	2	effect	effect	NN
cord-002180-gsdk5x3e	93	3	of	of	IN
cord-002180-gsdk5x3e	93	4	NS5	NS5	NNP
cord-002180-gsdk5x3e	93	5	on	on	IN
cord-002180-gsdk5x3e	93	6	the	the	DT
cord-002180-gsdk5x3e	93	7	host	host	NN
cord-002180-gsdk5x3e	93	8	cell	cell	NN
cord-002180-gsdk5x3e	93	9	cycle	cycle	NN
cord-002180-gsdk5x3e	93	10	was	be	VBD
cord-002180-gsdk5x3e	93	11	therefore	therefore	RB
cord-002180-gsdk5x3e	93	12	determined	determine	VBN
cord-002180-gsdk5x3e	93	13	by	by	IN
cord-002180-gsdk5x3e	93	14	transfection	transfection	NN
cord-002180-gsdk5x3e	93	15	of	of	IN
cord-002180-gsdk5x3e	93	16	RAW	raw	JJ
cord-002180-gsdk5x3e	93	17	-	-	HYPH
cord-002180-gsdk5x3e	93	18	Blue	blue	JJ
cord-002180-gsdk5x3e	93	19	cells	cell	NNS
cord-002180-gsdk5x3e	93	20	with	with	IN
cord-002180-gsdk5x3e	93	21	RNA	RNA	NNP
cord-002180-gsdk5x3e	93	22	transcripts	transcript	NNS
cord-002180-gsdk5x3e	93	23	,	,	,
cord-002180-gsdk5x3e	93	24	encoding	encode	VBG
cord-002180-gsdk5x3e	93	25	individual	individual	JJ
cord-002180-gsdk5x3e	93	26	viral	viral	JJ
cord-002180-gsdk5x3e	93	27	genes	gene	NNS
cord-002180-gsdk5x3e	93	28	,	,	,
cord-002180-gsdk5x3e	93	29	NS1	ns1	NN
cord-002180-gsdk5x3e	93	30	-	-	HYPH
cord-002180-gsdk5x3e	93	31	2	2	CD
cord-002180-gsdk5x3e	93	32	from	from	IN
cord-002180-gsdk5x3e	93	33	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	93	34	was	be	VBD
cord-002180-gsdk5x3e	93	35	included	include	VBN
cord-002180-gsdk5x3e	93	36	as	as	IN
cord-002180-gsdk5x3e	93	37	a	a	DT
cord-002180-gsdk5x3e	93	38	negative	negative	JJ
cord-002180-gsdk5x3e	93	39	control	control	NN
cord-002180-gsdk5x3e	93	40	(	(	-LRB-
cord-002180-gsdk5x3e	93	41	Fig	Fig	NNP
cord-002180-gsdk5x3e	93	42	1A	1a	NN
cord-002180-gsdk5x3e	93	43	)	)	-RRB-
cord-002180-gsdk5x3e	93	44	.	.	.
cord-002180-gsdk5x3e	94	1	NS1	ns1	NN
cord-002180-gsdk5x3e	94	2	-	-	HYPH
cord-002180-gsdk5x3e	94	3	2	2	CD
cord-002180-gsdk5x3e	94	4	and	and	CC
cord-002180-gsdk5x3e	94	5	NS5	ns5	JJ
cord-002180-gsdk5x3e	94	6	were	be	VBD
cord-002180-gsdk5x3e	94	7	detected	detect	VBN
cord-002180-gsdk5x3e	94	8	by	by	IN
cord-002180-gsdk5x3e	94	9	their	-PRON-	PRP$
cord-002180-gsdk5x3e	94	10	corresponding	correspond	VBG
cord-002180-gsdk5x3e	94	11	antibodies	antibody	NNS
cord-002180-gsdk5x3e	94	12	18	18	CD
cord-002180-gsdk5x3e	94	13	h	h	NN
cord-002180-gsdk5x3e	94	14	posttransfection	posttransfection	NN
cord-002180-gsdk5x3e	94	15	(	(	-LRB-
cord-002180-gsdk5x3e	94	16	Fig	Fig	NNP
cord-002180-gsdk5x3e	94	17	1C	1c	NN
cord-002180-gsdk5x3e	94	18	)	)	-RRB-
cord-002180-gsdk5x3e	94	19	.	.	.
cord-002180-gsdk5x3e	95	1	Expression	expression	NN
cord-002180-gsdk5x3e	95	2	of	of	IN
cord-002180-gsdk5x3e	95	3	NS5	NS5	NNP
cord-002180-gsdk5x3e	95	4	increased	increase	VBD
cord-002180-gsdk5x3e	95	5	the	the	DT
cord-002180-gsdk5x3e	95	6	population	population	NN
cord-002180-gsdk5x3e	95	7	of	of	IN
cord-002180-gsdk5x3e	95	8	cells	cell	NNS
cord-002180-gsdk5x3e	95	9	in	in	IN
cord-002180-gsdk5x3e	95	10	the	the	DT
cord-002180-gsdk5x3e	95	11	G	g	NN
cord-002180-gsdk5x3e	95	12	0	0	CD
cord-002180-gsdk5x3e	95	13	/G	/g	SYM
cord-002180-gsdk5x3e	95	14	1	1	CD
cord-002180-gsdk5x3e	95	15	phase	phase	NN
cord-002180-gsdk5x3e	95	16	by	by	IN
cord-002180-gsdk5x3e	95	17	28	28	CD
cord-002180-gsdk5x3e	95	18	%	%	NN
cord-002180-gsdk5x3e	95	19	and	and	CC
cord-002180-gsdk5x3e	95	20	decreased	decrease	VBD
cord-002180-gsdk5x3e	95	21	the	the	DT
cord-002180-gsdk5x3e	95	22	S	S	NNP
cord-002180-gsdk5x3e	95	23	phase	phase	NN
cord-002180-gsdk5x3e	95	24	by	by	IN
cord-002180-gsdk5x3e	95	25	27	27	CD
cord-002180-gsdk5x3e	95	26	%	%	NN
cord-002180-gsdk5x3e	95	27	when	when	WRB
cord-002180-gsdk5x3e	95	28	compared	compare	VBN
cord-002180-gsdk5x3e	95	29	to	to	IN
cord-002180-gsdk5x3e	95	30	the	the	DT
cord-002180-gsdk5x3e	95	31	mock	mock	NN
cord-002180-gsdk5x3e	95	32	-	-	HYPH
cord-002180-gsdk5x3e	95	33	transfected	transfecte	VBN
cord-002180-gsdk5x3e	95	34	population	population	NN
cord-002180-gsdk5x3e	95	35	(	(	-LRB-
cord-002180-gsdk5x3e	95	36	Fig	Fig	NNP
cord-002180-gsdk5x3e	95	37	1B	1b	CD
cord-002180-gsdk5x3e	95	38	)	)	-RRB-
cord-002180-gsdk5x3e	95	39	.	.	.
cord-002180-gsdk5x3e	96	1	Furthermore	furthermore	RB
cord-002180-gsdk5x3e	96	2	,	,	,
cord-002180-gsdk5x3e	96	3	NS5	ns5	JJ
cord-002180-gsdk5x3e	96	4	expression	expression	NN
cord-002180-gsdk5x3e	96	5	decreased	decrease	VBD
cord-002180-gsdk5x3e	96	6	cyclin	cyclin	NN
cord-002180-gsdk5x3e	96	7	A	a	DT
cord-002180-gsdk5x3e	96	8	expression	expression	NN
cord-002180-gsdk5x3e	96	9	by	by	IN
cord-002180-gsdk5x3e	96	10	68	68	CD
cord-002180-gsdk5x3e	96	11	%	%	NN
cord-002180-gsdk5x3e	96	12	when	when	WRB
cord-002180-gsdk5x3e	96	13	compared	compare	VBN
cord-002180-gsdk5x3e	96	14	to	to	IN
cord-002180-gsdk5x3e	96	15	the	the	DT
cord-002180-gsdk5x3e	96	16	mock	mock	NN
cord-002180-gsdk5x3e	96	17	-	-	HYPH
cord-002180-gsdk5x3e	96	18	transfected	transfecte	VBN
cord-002180-gsdk5x3e	96	19	control	control	NN
cord-002180-gsdk5x3e	96	20	(	(	-LRB-
cord-002180-gsdk5x3e	96	21	Fig	Fig	NNP
cord-002180-gsdk5x3e	96	22	1D	1d	CD
cord-002180-gsdk5x3e	96	23	)	)	-RRB-
cord-002180-gsdk5x3e	96	24	.	.	.
cord-002180-gsdk5x3e	97	1	The	the	DT
cord-002180-gsdk5x3e	97	2	cyclin	cyclin	NN
cord-002180-gsdk5x3e	97	3	A	a	DT
cord-002180-gsdk5x3e	97	4	protein	protein	NN
cord-002180-gsdk5x3e	97	5	governs	govern	VBZ
cord-002180-gsdk5x3e	97	6	S	s	NN
cord-002180-gsdk5x3e	97	7	phase	phase	NN
cord-002180-gsdk5x3e	97	8	entry	entry	NN
cord-002180-gsdk5x3e	97	9	and	and	CC
cord-002180-gsdk5x3e	97	10	progression	progression	NN
cord-002180-gsdk5x3e	97	11	,	,	,
cord-002180-gsdk5x3e	97	12	so	so	IN
cord-002180-gsdk5x3e	97	13	a	a	DT
cord-002180-gsdk5x3e	97	14	decrease	decrease	NN
cord-002180-gsdk5x3e	97	15	in	in	IN
cord-002180-gsdk5x3e	97	16	expression	expression	NN
cord-002180-gsdk5x3e	97	17	would	would	MD
cord-002180-gsdk5x3e	97	18	imply	imply	VB
cord-002180-gsdk5x3e	97	19	a	a	DT
cord-002180-gsdk5x3e	97	20	decrease	decrease	NN
cord-002180-gsdk5x3e	97	21	in	in	IN
cord-002180-gsdk5x3e	97	22	S	s	NN
cord-002180-gsdk5x3e	97	23	phase	phase	NN
cord-002180-gsdk5x3e	97	24	entry	entry	NN
cord-002180-gsdk5x3e	97	25	,	,	,
cord-002180-gsdk5x3e	97	26	further	further	RB
cord-002180-gsdk5x3e	97	27	indicating	indicate	VBG
cord-002180-gsdk5x3e	97	28	NS5	ns5	JJ
cord-002180-gsdk5x3e	97	29	as	as	IN
cord-002180-gsdk5x3e	97	30	the	the	DT
cord-002180-gsdk5x3e	97	31	protein	protein	NN
cord-002180-gsdk5x3e	97	32	responsible	responsible	JJ
cord-002180-gsdk5x3e	97	33	for	for	IN
cord-002180-gsdk5x3e	97	34	the	the	DT
cord-002180-gsdk5x3e	97	35	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	97	36	induced	induce	VBN
cord-002180-gsdk5x3e	97	37	cell	cell	NN
cord-002180-gsdk5x3e	97	38	cycle	cycle	NN
cord-002180-gsdk5x3e	97	39	manipulation	manipulation	NN
cord-002180-gsdk5x3e	97	40	.	.	.
cord-002180-gsdk5x3e	98	1	NS1	ns1	NN
cord-002180-gsdk5x3e	98	2	-	-	HYPH
cord-002180-gsdk5x3e	98	3	2	2	CD
cord-002180-gsdk5x3e	98	4	had	have	VBD
cord-002180-gsdk5x3e	98	5	no	no	DT
cord-002180-gsdk5x3e	98	6	significant	significant	JJ
cord-002180-gsdk5x3e	98	7	effects	effect	NNS
cord-002180-gsdk5x3e	98	8	on	on	IN
cord-002180-gsdk5x3e	98	9	the	the	DT
cord-002180-gsdk5x3e	98	10	host	host	NN
cord-002180-gsdk5x3e	98	11	cell	cell	NN
cord-002180-gsdk5x3e	98	12	cycle	cycle	NN
cord-002180-gsdk5x3e	98	13	or	or	CC
cord-002180-gsdk5x3e	98	14	cyclin	cyclin	NN
cord-002180-gsdk5x3e	98	15	A	a	DT
cord-002180-gsdk5x3e	98	16	expression	expression	NN
cord-002180-gsdk5x3e	98	17	.	.	.
cord-002180-gsdk5x3e	99	1	If	if	IN
cord-002180-gsdk5x3e	99	2	the	the	DT
cord-002180-gsdk5x3e	99	3	NS5	ns5	JJ
cord-002180-gsdk5x3e	99	4	protein	protein	NN
cord-002180-gsdk5x3e	99	5	is	be	VBZ
cord-002180-gsdk5x3e	99	6	responsible	responsible	JJ
cord-002180-gsdk5x3e	99	7	for	for	IN
cord-002180-gsdk5x3e	99	8	the	the	DT
cord-002180-gsdk5x3e	99	9	cell	cell	NN
cord-002180-gsdk5x3e	99	10	cycle	cycle	NN
cord-002180-gsdk5x3e	99	11	arrest	arrest	NN
cord-002180-gsdk5x3e	99	12	,	,	,
cord-002180-gsdk5x3e	99	13	then	then	RB
cord-002180-gsdk5x3e	99	14	it	-PRON-	PRP
cord-002180-gsdk5x3e	99	15	should	should	MD
cord-002180-gsdk5x3e	99	16	induce	induce	VB
cord-002180-gsdk5x3e	99	17	its	-PRON-	PRP$
cord-002180-gsdk5x3e	99	18	cell	cell	NN
cord-002180-gsdk5x3e	99	19	cycle	cycle	NN
cord-002180-gsdk5x3e	99	20	arrest	arrest	NN
cord-002180-gsdk5x3e	99	21	at	at	IN
cord-002180-gsdk5x3e	99	22	the	the	DT
cord-002180-gsdk5x3e	99	23	G	g	NN
cord-002180-gsdk5x3e	99	24	1	1	CD
cord-002180-gsdk5x3e	99	25	/S	/S	NNP
cord-002180-gsdk5x3e	99	26	restriction	restriction	NN
cord-002180-gsdk5x3e	99	27	point	point	NN
cord-002180-gsdk5x3e	99	28	,	,	,
cord-002180-gsdk5x3e	99	29	as	as	IN
cord-002180-gsdk5x3e	99	30	observed	observe	VBN
cord-002180-gsdk5x3e	99	31	during	during	IN
cord-002180-gsdk5x3e	99	32	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	99	33	infections	infection	NNS
cord-002180-gsdk5x3e	99	34	[	[	-LRB-
cord-002180-gsdk5x3e	99	35	20	20	CD
cord-002180-gsdk5x3e	99	36	]	]	-RRB-
cord-002180-gsdk5x3e	99	37	.	.	.
cord-002180-gsdk5x3e	100	1	The	the	DT
cord-002180-gsdk5x3e	100	2	transition	transition	NN
cord-002180-gsdk5x3e	100	3	through	through	IN
cord-002180-gsdk5x3e	100	4	G	g	NN
cord-002180-gsdk5x3e	100	5	1	1	CD
cord-002180-gsdk5x3e	100	6	/S	/S	NNPS
cord-002180-gsdk5x3e	100	7	is	be	VBZ
cord-002180-gsdk5x3e	100	8	a	a	DT
cord-002180-gsdk5x3e	100	9	highly	highly	RB
cord-002180-gsdk5x3e	100	10	regulated	regulate	VBN
cord-002180-gsdk5x3e	100	11	checkpoint	checkpoint	NN
cord-002180-gsdk5x3e	100	12	during	during	IN
cord-002180-gsdk5x3e	100	13	cell	cell	NN
cord-002180-gsdk5x3e	100	14	division	division	NN
cord-002180-gsdk5x3e	100	15	and	and	CC
cord-002180-gsdk5x3e	100	16	is	be	VBZ
cord-002180-gsdk5x3e	100	17	often	often	RB
cord-002180-gsdk5x3e	100	18	targeted	target	VBN
cord-002180-gsdk5x3e	100	19	by	by	IN
cord-002180-gsdk5x3e	100	20	viruses	virus	NNS
cord-002180-gsdk5x3e	100	21	to	to	TO
cord-002180-gsdk5x3e	100	22	induce	induce	VB
cord-002180-gsdk5x3e	100	23	changes	change	NNS
cord-002180-gsdk5x3e	100	24	to	to	IN
cord-002180-gsdk5x3e	100	25	the	the	DT
cord-002180-gsdk5x3e	100	26	host	host	NN
cord-002180-gsdk5x3e	100	27	cell	cell	NN
cord-002180-gsdk5x3e	100	28	cycle	cycle	NN
cord-002180-gsdk5x3e	100	29	[	[	-LRB-
cord-002180-gsdk5x3e	100	30	14	14	CD
cord-002180-gsdk5x3e	100	31	,	,	,
cord-002180-gsdk5x3e	100	32	18	18	CD
cord-002180-gsdk5x3e	100	33	,	,	,
cord-002180-gsdk5x3e	100	34	31	31	CD
cord-002180-gsdk5x3e	100	35	,	,	,
cord-002180-gsdk5x3e	100	36	32	32	CD
cord-002180-gsdk5x3e	100	37	]	]	-RRB-
cord-002180-gsdk5x3e	100	38	.	.	.
cord-002180-gsdk5x3e	101	1	The	the	DT
cord-002180-gsdk5x3e	101	2	transition	transition	NN
cord-002180-gsdk5x3e	101	3	of	of	IN
cord-002180-gsdk5x3e	101	4	cells	cell	NNS
cord-002180-gsdk5x3e	101	5	through	through	IN
cord-002180-gsdk5x3e	101	6	the	the	DT
cord-002180-gsdk5x3e	101	7	G	g	NN
cord-002180-gsdk5x3e	101	8	1	1	CD
cord-002180-gsdk5x3e	101	9	/S	/S	NNP
cord-002180-gsdk5x3e	101	10	restriction	restriction	NN
cord-002180-gsdk5x3e	101	11	point	point	NN
cord-002180-gsdk5x3e	101	12	was	be	VBD
cord-002180-gsdk5x3e	101	13	examined	examine	VBN
cord-002180-gsdk5x3e	101	14	in	in	IN
cord-002180-gsdk5x3e	101	15	cells	cell	NNS
cord-002180-gsdk5x3e	101	16	expressing	express	VBG
cord-002180-gsdk5x3e	101	17	NS5	ns5	JJ
cord-002180-gsdk5x3e	101	18	.	.	.
cord-002180-gsdk5x3e	102	1	Cells	cell	NNS
cord-002180-gsdk5x3e	102	2	were	be	VBD
cord-002180-gsdk5x3e	102	3	synchronized	synchronize	VBN
cord-002180-gsdk5x3e	102	4	to	to	IN
cord-002180-gsdk5x3e	102	5	the	the	DT
cord-002180-gsdk5x3e	102	6	G	g	NN
cord-002180-gsdk5x3e	102	7	1	1	CD
cord-002180-gsdk5x3e	102	8	phase	phase	NN
cord-002180-gsdk5x3e	102	9	through	through	IN
cord-002180-gsdk5x3e	102	10	N	n	CD
cord-002180-gsdk5x3e	102	11	-	-	HYPH
cord-002180-gsdk5x3e	102	12	butyrate	butyrate	NN
cord-002180-gsdk5x3e	102	13	treatment	treatment	NN
cord-002180-gsdk5x3e	102	14	,	,	,
cord-002180-gsdk5x3e	102	15	released	release	VBN
cord-002180-gsdk5x3e	102	16	from	from	IN
cord-002180-gsdk5x3e	102	17	the	the	DT
cord-002180-gsdk5x3e	102	18	arrest	arrest	NN
cord-002180-gsdk5x3e	102	19	and	and	CC
cord-002180-gsdk5x3e	102	20	transfected	transfecte	VBN
cord-002180-gsdk5x3e	102	21	with	with	IN
cord-002180-gsdk5x3e	102	22	NS5	ns5	JJ
cord-002180-gsdk5x3e	102	23	,	,	,
cord-002180-gsdk5x3e	102	24	NS1	ns1	NN
cord-002180-gsdk5x3e	102	25	-	-	HYPH
cord-002180-gsdk5x3e	102	26	2	2	CD
cord-002180-gsdk5x3e	102	27	and	and	CC
cord-002180-gsdk5x3e	102	28	GFP	GFP	NNP
cord-002180-gsdk5x3e	102	29	coding	code	VBG
cord-002180-gsdk5x3e	102	30	RNA	RNA	NNP
cord-002180-gsdk5x3e	102	31	.	.	.
cord-002180-gsdk5x3e	103	1	NS1	ns1	NN
cord-002180-gsdk5x3e	103	2	-	-	HYPH
cord-002180-gsdk5x3e	103	3	2	2	CD
cord-002180-gsdk5x3e	103	4	was	be	VBD
cord-002180-gsdk5x3e	103	5	used	use	VBN
cord-002180-gsdk5x3e	103	6	as	as	IN
cord-002180-gsdk5x3e	103	7	a	a	DT
cord-002180-gsdk5x3e	103	8	viral	viral	JJ
cord-002180-gsdk5x3e	103	9	control	control	NN
cord-002180-gsdk5x3e	103	10	protein	protein	NN
cord-002180-gsdk5x3e	103	11	that	that	WDT
cord-002180-gsdk5x3e	103	12	did	do	VBD
cord-002180-gsdk5x3e	103	13	not	not	RB
cord-002180-gsdk5x3e	103	14	affect	affect	VB
cord-002180-gsdk5x3e	103	15	the	the	DT
cord-002180-gsdk5x3e	103	16	cell	cell	NN
cord-002180-gsdk5x3e	103	17	cycle	cycle	NN
cord-002180-gsdk5x3e	103	18	and	and	CC
cord-002180-gsdk5x3e	103	19	GFP	GFP	NNP
cord-002180-gsdk5x3e	103	20	as	as	IN
cord-002180-gsdk5x3e	103	21	a	a	DT
cord-002180-gsdk5x3e	103	22	non	non	JJ
cord-002180-gsdk5x3e	103	23	-	-	JJ
cord-002180-gsdk5x3e	103	24	viral	viral	JJ
cord-002180-gsdk5x3e	103	25	RNA	RNA	NNP
cord-002180-gsdk5x3e	103	26	negative	negative	JJ
cord-002180-gsdk5x3e	103	27	control	control	NN
cord-002180-gsdk5x3e	103	28	.	.	.
cord-002180-gsdk5x3e	104	1	N	n	NN
cord-002180-gsdk5x3e	104	2	-	-	HYPH
cord-002180-gsdk5x3e	104	3	butyrate	butyrate	NNP
cord-002180-gsdk5x3e	104	4	was	be	VBD
cord-002180-gsdk5x3e	104	5	also	also	RB
cord-002180-gsdk5x3e	104	6	added	add	VBN
cord-002180-gsdk5x3e	104	7	to	to	IN
cord-002180-gsdk5x3e	104	8	released	release	VBN
cord-002180-gsdk5x3e	104	9	populations	population	NNS
cord-002180-gsdk5x3e	104	10	and	and	CC
cord-002180-gsdk5x3e	104	11	used	use	VBD
cord-002180-gsdk5x3e	104	12	as	as	IN
cord-002180-gsdk5x3e	104	13	a	a	DT
cord-002180-gsdk5x3e	104	14	positive	positive	JJ
cord-002180-gsdk5x3e	104	15	control	control	NN
cord-002180-gsdk5x3e	104	16	.	.	.
cord-002180-gsdk5x3e	105	1	Cells	cell	NNS
cord-002180-gsdk5x3e	105	2	were	be	VBD
cord-002180-gsdk5x3e	105	3	then	then	RB
cord-002180-gsdk5x3e	105	4	analyzed	analyze	VBN
cord-002180-gsdk5x3e	105	5	for	for	IN
cord-002180-gsdk5x3e	105	6	their	-PRON-	PRP$
cord-002180-gsdk5x3e	105	7	transition	transition	NN
cord-002180-gsdk5x3e	105	8	from	from	IN
cord-002180-gsdk5x3e	105	9	G	g	NN
cord-002180-gsdk5x3e	105	10	1	1	CD
cord-002180-gsdk5x3e	105	11	into	into	IN
cord-002180-gsdk5x3e	105	12	S	s	NN
cord-002180-gsdk5x3e	105	13	phase	phase	NN
cord-002180-gsdk5x3e	105	14	by	by	IN
cord-002180-gsdk5x3e	105	15	FACS	FACS	NNP
cord-002180-gsdk5x3e	105	16	analysis	analysis	NN
cord-002180-gsdk5x3e	105	17	of	of	IN
cord-002180-gsdk5x3e	105	18	the	the	DT
cord-002180-gsdk5x3e	105	19	host	host	NN
cord-002180-gsdk5x3e	105	20	cell	cell	NN
cord-002180-gsdk5x3e	105	21	cycle	cycle	NN
cord-002180-gsdk5x3e	105	22	.	.	.
cord-002180-gsdk5x3e	106	1	GFP	GFP	NNP
cord-002180-gsdk5x3e	106	2	,	,	,
cord-002180-gsdk5x3e	106	3	NS1	ns1	NN
cord-002180-gsdk5x3e	106	4	-	-	HYPH
cord-002180-gsdk5x3e	106	5	2	2	CD
cord-002180-gsdk5x3e	106	6	and	and	CC
cord-002180-gsdk5x3e	106	7	NS5	NS5	NNP
cord-002180-gsdk5x3e	106	8	RNA	RNA	NNP
cord-002180-gsdk5x3e	106	9	transcripts	transcript	NNS
cord-002180-gsdk5x3e	106	10	were	be	VBD
cord-002180-gsdk5x3e	106	11	translated	translate	VBN
cord-002180-gsdk5x3e	106	12	into	into	IN
cord-002180-gsdk5x3e	106	13	protein	protein	NN
cord-002180-gsdk5x3e	106	14	and	and	CC
cord-002180-gsdk5x3e	106	15	detected	detect	VBD
cord-002180-gsdk5x3e	106	16	from	from	IN
cord-002180-gsdk5x3e	106	17	15	15	CD
cord-002180-gsdk5x3e	106	18	to	to	TO
cord-002180-gsdk5x3e	106	19	24	24	CD
cord-002180-gsdk5x3e	106	20	hours	hour	NNS
cord-002180-gsdk5x3e	106	21	post	post	NN
cord-002180-gsdk5x3e	106	22	-	-	JJ
cord-002180-gsdk5x3e	106	23	G	g	JJ
cord-002180-gsdk5x3e	106	24	1	1	CD
cord-002180-gsdk5x3e	106	25	release	release	NN
cord-002180-gsdk5x3e	106	26	(	(	-LRB-
cord-002180-gsdk5x3e	106	27	Fig	Fig	NNP
cord-002180-gsdk5x3e	106	28	2A	2a	CD
cord-002180-gsdk5x3e	106	29	)	)	-RRB-
cord-002180-gsdk5x3e	106	30	.	.	.
cord-002180-gsdk5x3e	107	1	The	the	DT
cord-002180-gsdk5x3e	107	2	Nbutyrate	Nbutyrate	NNP
cord-002180-gsdk5x3e	107	3	treated	treat	VBN
cord-002180-gsdk5x3e	107	4	cells	cell	NNS
cord-002180-gsdk5x3e	107	5	remained	remain	VBD
cord-002180-gsdk5x3e	107	6	predominantly	predominantly	RB
cord-002180-gsdk5x3e	107	7	in	in	IN
cord-002180-gsdk5x3e	107	8	G	g	NN
cord-002180-gsdk5x3e	107	9	1	1	CD
cord-002180-gsdk5x3e	107	10	phase	phase	NN
cord-002180-gsdk5x3e	107	11	post	post	NN
cord-002180-gsdk5x3e	107	12	-	-	NN
cord-002180-gsdk5x3e	107	13	release	release	NN
cord-002180-gsdk5x3e	107	14	while	while	IN
cord-002180-gsdk5x3e	107	15	the	the	DT
cord-002180-gsdk5x3e	107	16	mock	mock	NN
cord-002180-gsdk5x3e	107	17	-	-	HYPH
cord-002180-gsdk5x3e	107	18	transfected	transfecte	VBN
cord-002180-gsdk5x3e	107	19	cells	cell	NNS
cord-002180-gsdk5x3e	107	20	came	come	VBD
cord-002180-gsdk5x3e	107	21	out	out	IN
cord-002180-gsdk5x3e	107	22	of	of	IN
cord-002180-gsdk5x3e	107	23	the	the	DT
cord-002180-gsdk5x3e	107	24	G	g	NN
cord-002180-gsdk5x3e	107	25	1	1	CD
cord-002180-gsdk5x3e	107	26	arrest	arrest	NN
cord-002180-gsdk5x3e	107	27	,	,	,
cord-002180-gsdk5x3e	107	28	indicated	indicate	VBN
cord-002180-gsdk5x3e	107	29	by	by	IN
cord-002180-gsdk5x3e	107	30	a	a	DT
cord-002180-gsdk5x3e	107	31	decrease	decrease	NN
cord-002180-gsdk5x3e	107	32	in	in	IN
cord-002180-gsdk5x3e	107	33	the	the	DT
cord-002180-gsdk5x3e	107	34	G	g	NN
cord-002180-gsdk5x3e	107	35	0	0	CD
cord-002180-gsdk5x3e	107	36	/G	/g	SYM
cord-002180-gsdk5x3e	107	37	1	1	CD
cord-002180-gsdk5x3e	107	38	population	population	NN
cord-002180-gsdk5x3e	107	39	and	and	CC
cord-002180-gsdk5x3e	107	40	an	an	DT
cord-002180-gsdk5x3e	107	41	increase	increase	NN
cord-002180-gsdk5x3e	107	42	in	in	IN
cord-002180-gsdk5x3e	107	43	the	the	DT
cord-002180-gsdk5x3e	107	44	S	S	NNP
cord-002180-gsdk5x3e	107	45	phase	phase	NN
cord-002180-gsdk5x3e	107	46	cells	cell	NNS
cord-002180-gsdk5x3e	107	47	post	post	VBP
cord-002180-gsdk5x3e	107	48	-	-	JJ
cord-002180-gsdk5x3e	107	49	release	release	NN
cord-002180-gsdk5x3e	107	50	(	(	-LRB-
cord-002180-gsdk5x3e	107	51	Fig	Fig	NNP
cord-002180-gsdk5x3e	107	52	2C	2c	NN
cord-002180-gsdk5x3e	107	53	)	)	-RRB-
cord-002180-gsdk5x3e	107	54	.	.	.
cord-002180-gsdk5x3e	108	1	Transfection	Transfection	NNP
cord-002180-gsdk5x3e	108	2	of	of	IN
cord-002180-gsdk5x3e	108	3	GFP	GFP	NNP
cord-002180-gsdk5x3e	108	4	and	and	CC
cord-002180-gsdk5x3e	108	5	NS1	ns1	NN
cord-002180-gsdk5x3e	108	6	-	-	HYPH
cord-002180-gsdk5x3e	108	7	2	2	CD
cord-002180-gsdk5x3e	109	1	RNA	RNA	NNP
cord-002180-gsdk5x3e	109	2	had	have	VBD
cord-002180-gsdk5x3e	109	3	no	no	DT
cord-002180-gsdk5x3e	109	4	effect	effect	NN
cord-002180-gsdk5x3e	109	5	on	on	IN
cord-002180-gsdk5x3e	109	6	the	the	DT
cord-002180-gsdk5x3e	109	7	transition	transition	NN
cord-002180-gsdk5x3e	109	8	of	of	IN
cord-002180-gsdk5x3e	109	9	cells	cell	NNS
cord-002180-gsdk5x3e	109	10	from	from	IN
cord-002180-gsdk5x3e	109	11	G	g	NN
cord-002180-gsdk5x3e	109	12	1	1	CD
cord-002180-gsdk5x3e	109	13	into	into	IN
cord-002180-gsdk5x3e	109	14	S	s	NN
cord-002180-gsdk5x3e	109	15	phase	phase	NN
cord-002180-gsdk5x3e	109	16	compared	compare	VBN
cord-002180-gsdk5x3e	109	17	to	to	IN
cord-002180-gsdk5x3e	109	18	the	the	DT
cord-002180-gsdk5x3e	109	19	mock	mock	NN
cord-002180-gsdk5x3e	109	20	-	-	HYPH
cord-002180-gsdk5x3e	109	21	transfected	transfecte	VBN
cord-002180-gsdk5x3e	109	22	population	population	NN
cord-002180-gsdk5x3e	109	23	,	,	,
cord-002180-gsdk5x3e	109	24	with	with	IN
cord-002180-gsdk5x3e	109	25	both	both	CC
cord-002180-gsdk5x3e	109	26	GFP	GFP	NNP
cord-002180-gsdk5x3e	109	27	and	and	CC
cord-002180-gsdk5x3e	109	28	NS1	ns1	NN
cord-002180-gsdk5x3e	109	29	-	-	HYPH
cord-002180-gsdk5x3e	109	30	2	2	CD
cord-002180-gsdk5x3e	109	31	transfected	transfecte	VBN
cord-002180-gsdk5x3e	109	32	populations	population	NNS
cord-002180-gsdk5x3e	109	33	progressing	progress	VBG
cord-002180-gsdk5x3e	109	34	into	into	IN
cord-002180-gsdk5x3e	109	35	S	s	NN
cord-002180-gsdk5x3e	109	36	phase	phase	NN
cord-002180-gsdk5x3e	109	37	,	,	,
cord-002180-gsdk5x3e	109	38	with	with	IN
cord-002180-gsdk5x3e	109	39	a	a	DT
cord-002180-gsdk5x3e	109	40	substantial	substantial	JJ
cord-002180-gsdk5x3e	109	41	decrease	decrease	NN
cord-002180-gsdk5x3e	109	42	in	in	IN
cord-002180-gsdk5x3e	109	43	the	the	DT
cord-002180-gsdk5x3e	109	44	G	g	NN
cord-002180-gsdk5x3e	109	45	0	0	CD
cord-002180-gsdk5x3e	109	46	/G	/g	SYM
cord-002180-gsdk5x3e	109	47	1	1	CD
cord-002180-gsdk5x3e	109	48	population	population	NN
cord-002180-gsdk5x3e	109	49	observed	observe	VBN
cord-002180-gsdk5x3e	109	50	at	at	IN
cord-002180-gsdk5x3e	109	51	21	21	CD
cord-002180-gsdk5x3e	109	52	hours	hour	NNS
cord-002180-gsdk5x3e	109	53	post	post	NN
cord-002180-gsdk5x3e	109	54	-	-	JJ
cord-002180-gsdk5x3e	109	55	release	release	JJ
cord-002180-gsdk5x3e	109	56	,	,	,
cord-002180-gsdk5x3e	109	57	similar	similar	JJ
cord-002180-gsdk5x3e	109	58	to	to	IN
cord-002180-gsdk5x3e	109	59	the	the	DT
cord-002180-gsdk5x3e	109	60	mock	mock	NN
cord-002180-gsdk5x3e	109	61	-	-	HYPH
cord-002180-gsdk5x3e	109	62	transfected	transfecte	VBN
cord-002180-gsdk5x3e	109	63	population	population	NN
cord-002180-gsdk5x3e	109	64	(	(	-LRB-
cord-002180-gsdk5x3e	109	65	Fig	Fig	NNP
cord-002180-gsdk5x3e	109	66	2C	2c	NN
cord-002180-gsdk5x3e	109	67	)	)	-RRB-
cord-002180-gsdk5x3e	109	68	.	.	.
cord-002180-gsdk5x3e	110	1	In	in	IN
cord-002180-gsdk5x3e	110	2	contrast	contrast	NN
cord-002180-gsdk5x3e	110	3	,	,	,
cord-002180-gsdk5x3e	110	4	transfection	transfection	NN
cord-002180-gsdk5x3e	110	5	of	of	IN
cord-002180-gsdk5x3e	110	6	NS5	NS5	NNP
cord-002180-gsdk5x3e	110	7	RNA	RNA	NNP
cord-002180-gsdk5x3e	110	8	induced	induce	VBD
cord-002180-gsdk5x3e	110	9	a	a	DT
cord-002180-gsdk5x3e	110	10	G	g	NN
cord-002180-gsdk5x3e	110	11	1	1	CD
cord-002180-gsdk5x3e	110	12	/S	/S	NNP
cord-002180-gsdk5x3e	110	13	phase	phase	NN
cord-002180-gsdk5x3e	110	14	arrest	arrest	NN
cord-002180-gsdk5x3e	110	15	,	,	,
cord-002180-gsdk5x3e	110	16	as	as	IN
cord-002180-gsdk5x3e	110	17	indicated	indicate	VBN
cord-002180-gsdk5x3e	110	18	by	by	IN
cord-002180-gsdk5x3e	110	19	cells	cell	NNS
cord-002180-gsdk5x3e	110	20	remaining	remain	VBG
cord-002180-gsdk5x3e	110	21	in	in	IN
cord-002180-gsdk5x3e	110	22	the	the	DT
cord-002180-gsdk5x3e	110	23	G	g	NN
cord-002180-gsdk5x3e	110	24	1	1	CD
cord-002180-gsdk5x3e	110	25	phase	phase	NN
cord-002180-gsdk5x3e	110	26	post	post	NN
cord-002180-gsdk5x3e	110	27	-	-	JJ
cord-002180-gsdk5x3e	110	28	release	release	NN
cord-002180-gsdk5x3e	110	29	,	,	,
cord-002180-gsdk5x3e	110	30	with	with	IN
cord-002180-gsdk5x3e	110	31	no	no	DT
cord-002180-gsdk5x3e	110	32	increase	increase	NN
cord-002180-gsdk5x3e	110	33	in	in	IN
cord-002180-gsdk5x3e	110	34	the	the	DT
cord-002180-gsdk5x3e	110	35	S	S	NNP
cord-002180-gsdk5x3e	110	36	phase	phase	NN
cord-002180-gsdk5x3e	110	37	population	population	NN
cord-002180-gsdk5x3e	110	38	.	.	.
cord-002180-gsdk5x3e	111	1	At	at	IN
cord-002180-gsdk5x3e	111	2	24	24	CD
cord-002180-gsdk5x3e	111	3	hours	hour	NNS
cord-002180-gsdk5x3e	111	4	post	post	NN
cord-002180-gsdk5x3e	111	5	-	-	NN
cord-002180-gsdk5x3e	111	6	release	release	NN
cord-002180-gsdk5x3e	111	7	in	in	IN
cord-002180-gsdk5x3e	111	8	NS5	ns5	JJ
cord-002180-gsdk5x3e	111	9	transfected	transfecte	VBN
cord-002180-gsdk5x3e	111	10	populations	population	NNS
cord-002180-gsdk5x3e	111	11	,	,	,
cord-002180-gsdk5x3e	111	12	73	73	CD
cord-002180-gsdk5x3e	111	13	%	%	NN
cord-002180-gsdk5x3e	111	14	of	of	IN
cord-002180-gsdk5x3e	111	15	cells	cell	NNS
cord-002180-gsdk5x3e	111	16	remained	remain	VBD
cord-002180-gsdk5x3e	111	17	in	in	IN
cord-002180-gsdk5x3e	111	18	the	the	DT
cord-002180-gsdk5x3e	111	19	G	g	NN
cord-002180-gsdk5x3e	111	20	0	0	CD
cord-002180-gsdk5x3e	111	21	/G	/g	SYM
cord-002180-gsdk5x3e	111	22	1	1	CD
cord-002180-gsdk5x3e	111	23	phase	phase	NN
cord-002180-gsdk5x3e	111	24	compared	compare	VBN
cord-002180-gsdk5x3e	111	25	to	to	IN
cord-002180-gsdk5x3e	111	26	46	46	CD
cord-002180-gsdk5x3e	111	27	%	%	NN
cord-002180-gsdk5x3e	111	28	in	in	IN
cord-002180-gsdk5x3e	111	29	the	the	DT
cord-002180-gsdk5x3e	111	30	mock	mock	NN
cord-002180-gsdk5x3e	111	31	-	-	HYPH
cord-002180-gsdk5x3e	111	32	transfected	transfecte	VBN
cord-002180-gsdk5x3e	111	33	population	population	NN
cord-002180-gsdk5x3e	111	34	(	(	-LRB-
cord-002180-gsdk5x3e	111	35	Fig	Fig	NNP
cord-002180-gsdk5x3e	111	36	2C	2c	NN
cord-002180-gsdk5x3e	111	37	)	)	-RRB-
cord-002180-gsdk5x3e	111	38	.	.	.
cord-002180-gsdk5x3e	112	1	Because	because	IN
cord-002180-gsdk5x3e	112	2	cyclin	cyclin	NN
cord-002180-gsdk5x3e	112	3	A	a	DT
cord-002180-gsdk5x3e	112	4	expression	expression	NN
cord-002180-gsdk5x3e	112	5	is	be	VBZ
cord-002180-gsdk5x3e	112	6	inhibited	inhibit	VBN
cord-002180-gsdk5x3e	112	7	by	by	IN
cord-002180-gsdk5x3e	112	8	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	112	9	infection	infection	NN
cord-002180-gsdk5x3e	112	10	in	in	IN
cord-002180-gsdk5x3e	112	11	cells	cell	NNS
cord-002180-gsdk5x3e	112	12	transitioning	transition	VBG
cord-002180-gsdk5x3e	112	13	through	through	IN
cord-002180-gsdk5x3e	112	14	the	the	DT
cord-002180-gsdk5x3e	112	15	G	g	NN
cord-002180-gsdk5x3e	112	16	1	1	CD
cord-002180-gsdk5x3e	112	17	/S	/S	NNP
cord-002180-gsdk5x3e	112	18	restriction	restriction	NN
cord-002180-gsdk5x3e	112	19	point	point	NN
cord-002180-gsdk5x3e	112	20	[	[	-LRB-
cord-002180-gsdk5x3e	112	21	20	20	CD
cord-002180-gsdk5x3e	112	22	]	]	-RRB-
cord-002180-gsdk5x3e	112	23	,	,	,
cord-002180-gsdk5x3e	112	24	cells	cell	NNS
cord-002180-gsdk5x3e	112	25	were	be	VBD
cord-002180-gsdk5x3e	112	26	analyzed	analyze	VBN
cord-002180-gsdk5x3e	112	27	post	post	JJ
cord-002180-gsdk5x3e	112	28	-	-	JJ
cord-002180-gsdk5x3e	112	29	G	g	JJ
cord-002180-gsdk5x3e	112	30	1	1	CD
cord-002180-gsdk5x3e	112	31	release	release	NN
cord-002180-gsdk5x3e	112	32	for	for	IN
cord-002180-gsdk5x3e	112	33	cyclin	cyclin	NN
cord-002180-gsdk5x3e	112	34	A	a	DT
cord-002180-gsdk5x3e	112	35	expression	expression	NN
cord-002180-gsdk5x3e	112	36	by	by	IN
cord-002180-gsdk5x3e	112	37	Western	western	JJ
cord-002180-gsdk5x3e	112	38	blot	blot	NN
cord-002180-gsdk5x3e	112	39	analysis	analysis	NN
cord-002180-gsdk5x3e	112	40	.	.	.
cord-002180-gsdk5x3e	113	1	Expression	expression	NN
cord-002180-gsdk5x3e	113	2	of	of	IN
cord-002180-gsdk5x3e	113	3	NS5	NS5	NNP
cord-002180-gsdk5x3e	113	4	inhibited	inhibit	VBD
cord-002180-gsdk5x3e	113	5	the	the	DT
cord-002180-gsdk5x3e	113	6	accumulation	accumulation	NN
cord-002180-gsdk5x3e	113	7	of	of	IN
cord-002180-gsdk5x3e	113	8	cyclin	cyclin	NN
cord-002180-gsdk5x3e	113	9	A	a	NN
cord-002180-gsdk5x3e	113	10	in	in	IN
cord-002180-gsdk5x3e	113	11	populations	population	NNS
cord-002180-gsdk5x3e	113	12	progressing	progress	VBG
cord-002180-gsdk5x3e	113	13	from	from	IN
cord-002180-gsdk5x3e	113	14	G	g	NN
cord-002180-gsdk5x3e	113	15	1	1	CD
cord-002180-gsdk5x3e	113	16	to	to	IN
cord-002180-gsdk5x3e	113	17	S	s	NN
cord-002180-gsdk5x3e	113	18	phase	phase	NN
cord-002180-gsdk5x3e	113	19	.	.	.
cord-002180-gsdk5x3e	114	1	In	in	IN
cord-002180-gsdk5x3e	114	2	a	a	DT
cord-002180-gsdk5x3e	114	3	G	g	NN
cord-002180-gsdk5x3e	114	4	1	1	CD
cord-002180-gsdk5x3e	114	5	arrested	arrest	VBD
cord-002180-gsdk5x3e	114	6	population	population	NN
cord-002180-gsdk5x3e	114	7	expression	expression	NN
cord-002180-gsdk5x3e	114	8	of	of	IN
cord-002180-gsdk5x3e	114	9	cyclin	cyclin	NN
cord-002180-gsdk5x3e	114	10	A	a	NN
cord-002180-gsdk5x3e	114	11	is	be	VBZ
cord-002180-gsdk5x3e	114	12	low	low	JJ
cord-002180-gsdk5x3e	114	13	,	,	,
cord-002180-gsdk5x3e	114	14	indicated	indicate	VBN
cord-002180-gsdk5x3e	114	15	by	by	IN
cord-002180-gsdk5x3e	114	16	undetectable	undetectable	JJ
cord-002180-gsdk5x3e	114	17	levels	level	NNS
cord-002180-gsdk5x3e	114	18	of	of	IN
cord-002180-gsdk5x3e	114	19	cyclin	cyclin	NN
cord-002180-gsdk5x3e	114	20	A	a	NN
cord-002180-gsdk5x3e	114	21	in	in	IN
cord-002180-gsdk5x3e	114	22	N	n	CD
cord-002180-gsdk5x3e	114	23	-	-	HYPH
cord-002180-gsdk5x3e	114	24	butyrate	butyrate	NN
cord-002180-gsdk5x3e	114	25	treated	treat	VBD
cord-002180-gsdk5x3e	114	26	cells	cell	NNS
cord-002180-gsdk5x3e	114	27	(	(	-LRB-
cord-002180-gsdk5x3e	114	28	Fig	Fig	NNP
cord-002180-gsdk5x3e	114	29	2D	2d	NN
cord-002180-gsdk5x3e	114	30	)	)	-RRB-
cord-002180-gsdk5x3e	114	31	.	.	.
cord-002180-gsdk5x3e	115	1	In	in	IN
cord-002180-gsdk5x3e	115	2	mock	mock	NN
cord-002180-gsdk5x3e	115	3	-	-	HYPH
cord-002180-gsdk5x3e	115	4	transfected	transfecte	VBN
cord-002180-gsdk5x3e	115	5	,	,	,
cord-002180-gsdk5x3e	115	6	GFP	GFP	NNP
cord-002180-gsdk5x3e	115	7	and	and	CC
cord-002180-gsdk5x3e	115	8	NS1	ns1	NN
cord-002180-gsdk5x3e	115	9	-	-	HYPH
cord-002180-gsdk5x3e	115	10	2	2	CD
cord-002180-gsdk5x3e	115	11	transfected	transfecte	VBN
cord-002180-gsdk5x3e	115	12	populations	population	NNS
cord-002180-gsdk5x3e	115	13	,	,	,
cord-002180-gsdk5x3e	115	14	cyclin	cyclin	VB
cord-002180-gsdk5x3e	115	15	A	a	DT
cord-002180-gsdk5x3e	115	16	expression	expression	NN
cord-002180-gsdk5x3e	115	17	increased	increase	VBD
cord-002180-gsdk5x3e	115	18	from	from	IN
cord-002180-gsdk5x3e	115	19	18	18	CD
cord-002180-gsdk5x3e	115	20	to	to	TO
cord-002180-gsdk5x3e	115	21	24	24	CD
cord-002180-gsdk5x3e	115	22	hours	hour	NNS
cord-002180-gsdk5x3e	115	23	post	post	NN
cord-002180-gsdk5x3e	115	24	-	-	NN
cord-002180-gsdk5x3e	115	25	release	release	NN
cord-002180-gsdk5x3e	115	26	as	as	IN
cord-002180-gsdk5x3e	115	27	cells	cell	NNS
cord-002180-gsdk5x3e	115	28	entered	enter	VBD
cord-002180-gsdk5x3e	115	29	S	S	NNP
cord-002180-gsdk5x3e	115	30	phase	phase	NN
cord-002180-gsdk5x3e	115	31	.	.	.
cord-002180-gsdk5x3e	116	1	In	in	IN
cord-002180-gsdk5x3e	116	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	116	3	transfected	transfected	JJ
cord-002180-gsdk5x3e	116	4	cells	cell	NNS
cord-002180-gsdk5x3e	116	5	,	,	,
cord-002180-gsdk5x3e	116	6	cyclin	cyclin	VB
cord-002180-gsdk5x3e	116	7	A	a	DT
cord-002180-gsdk5x3e	116	8	levels	level	NNS
cord-002180-gsdk5x3e	116	9	remained	remain	VBD
cord-002180-gsdk5x3e	116	10	below	below	IN
cord-002180-gsdk5x3e	116	11	detectable	detectable	JJ
cord-002180-gsdk5x3e	116	12	limits	limit	NNS
cord-002180-gsdk5x3e	116	13	post	post	VBP
cord-002180-gsdk5x3e	116	14	-	-	JJ
cord-002180-gsdk5x3e	116	15	release	release	NN
cord-002180-gsdk5x3e	116	16	,	,	,
cord-002180-gsdk5x3e	116	17	as	as	IN
cord-002180-gsdk5x3e	116	18	transfected	transfecte	VBN
cord-002180-gsdk5x3e	116	19	cells	cell	NNS
cord-002180-gsdk5x3e	116	20	remained	remain	VBD
cord-002180-gsdk5x3e	116	21	in	in	IN
cord-002180-gsdk5x3e	116	22	G	g	NN
cord-002180-gsdk5x3e	116	23	0	0	CD
cord-002180-gsdk5x3e	116	24	/G	/g	SYM
cord-002180-gsdk5x3e	116	25	1	1	CD
cord-002180-gsdk5x3e	116	26	phase	phase	NN
cord-002180-gsdk5x3e	116	27	and	and	CC
cord-002180-gsdk5x3e	116	28	did	do	VBD
cord-002180-gsdk5x3e	116	29	not	not	RB
cord-002180-gsdk5x3e	116	30	progress	progress	VB
cord-002180-gsdk5x3e	116	31	into	into	IN
cord-002180-gsdk5x3e	116	32	S	s	NN
cord-002180-gsdk5x3e	116	33	phase	phase	NN
cord-002180-gsdk5x3e	116	34	.	.	.
cord-002180-gsdk5x3e	117	1	These	these	DT
cord-002180-gsdk5x3e	117	2	results	result	NNS
cord-002180-gsdk5x3e	117	3	indicate	indicate	VBP
cord-002180-gsdk5x3e	117	4	that	that	IN
cord-002180-gsdk5x3e	117	5	NS5	NS5	NNP
cord-002180-gsdk5x3e	117	6	is	be	VBZ
cord-002180-gsdk5x3e	117	7	responsible	responsible	JJ
cord-002180-gsdk5x3e	117	8	the	the	DT
cord-002180-gsdk5x3e	117	9	cell	cell	NN
cord-002180-gsdk5x3e	117	10	cycle	cycle	NN
cord-002180-gsdk5x3e	117	11	arrest	arrest	NN
cord-002180-gsdk5x3e	117	12	induced	induce	VBN
cord-002180-gsdk5x3e	117	13	by	by	IN
cord-002180-gsdk5x3e	117	14	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	117	15	.	.	.
cord-002180-gsdk5x3e	118	1	Not	not	RB
cord-002180-gsdk5x3e	118	2	only	only	RB
cord-002180-gsdk5x3e	118	3	does	do	VBZ
cord-002180-gsdk5x3e	118	4	NS5	ns5	JJ
cord-002180-gsdk5x3e	118	5	expression	expression	NN
cord-002180-gsdk5x3e	118	6	increase	increase	VB
cord-002180-gsdk5x3e	118	7	the	the	DT
cord-002180-gsdk5x3e	118	8	G	g	NN
cord-002180-gsdk5x3e	118	9	0	0	CD
cord-002180-gsdk5x3e	118	10	/G	/g	SYM
cord-002180-gsdk5x3e	118	11	1	1	CD
cord-002180-gsdk5x3e	118	12	population	population	NN
cord-002180-gsdk5x3e	118	13	,	,	,
cord-002180-gsdk5x3e	118	14	but	but	CC
cord-002180-gsdk5x3e	118	15	it	-PRON-	PRP
cord-002180-gsdk5x3e	118	16	also	also	RB
cord-002180-gsdk5x3e	118	17	inhibits	inhibit	VBZ
cord-002180-gsdk5x3e	118	18	progression	progression	NN
cord-002180-gsdk5x3e	118	19	at	at	IN
cord-002180-gsdk5x3e	118	20	the	the	DT
cord-002180-gsdk5x3e	118	21	G	g	NN
cord-002180-gsdk5x3e	118	22	1	1	CD
cord-002180-gsdk5x3e	118	23	/S	/S	NNP
cord-002180-gsdk5x3e	118	24	restriction	restriction	NN
cord-002180-gsdk5x3e	118	25	point	point	NN
cord-002180-gsdk5x3e	118	26	and	and	CC
cord-002180-gsdk5x3e	118	27	inhibits	inhibit	VBZ
cord-002180-gsdk5x3e	118	28	cyclin	cyclin	NN
cord-002180-gsdk5x3e	118	29	A	a	DT
cord-002180-gsdk5x3e	118	30	expression	expression	NN
cord-002180-gsdk5x3e	118	31	.	.	.
cord-002180-gsdk5x3e	119	1	A	a	DT
cord-002180-gsdk5x3e	119	2	well	well	RB
cord-002180-gsdk5x3e	119	3	-	-	HYPH
cord-002180-gsdk5x3e	119	4	characterized	characterize	VBN
cord-002180-gsdk5x3e	119	5	function	function	NN
cord-002180-gsdk5x3e	119	6	of	of	IN
cord-002180-gsdk5x3e	119	7	NS5	ns5	JJ
cord-002180-gsdk5x3e	119	8	in	in	IN
cord-002180-gsdk5x3e	119	9	viral	viral	JJ
cord-002180-gsdk5x3e	119	10	replication	replication	NN
cord-002180-gsdk5x3e	119	11	is	be	VBZ
cord-002180-gsdk5x3e	119	12	to	to	TO
cord-002180-gsdk5x3e	119	13	recruit	recruit	VB
cord-002180-gsdk5x3e	119	14	host	host	NN
cord-002180-gsdk5x3e	119	15	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	119	16	initiation	initiation	NN
cord-002180-gsdk5x3e	119	17	factors	factor	NNS
cord-002180-gsdk5x3e	119	18	for	for	IN
cord-002180-gsdk5x3e	119	19	preferential	preferential	JJ
cord-002180-gsdk5x3e	119	20	translation	translation	NN
cord-002180-gsdk5x3e	119	21	of	of	IN
cord-002180-gsdk5x3e	119	22	viral	viral	JJ
cord-002180-gsdk5x3e	119	23	proteins	protein	NNS
cord-002180-gsdk5x3e	119	24	[	[	-LRB-
cord-002180-gsdk5x3e	119	25	30	30	CD
cord-002180-gsdk5x3e	119	26	,	,	,
cord-002180-gsdk5x3e	119	27	33	33	CD
cord-002180-gsdk5x3e	119	28	]	]	-RRB-
cord-002180-gsdk5x3e	119	29	.	.	.
cord-002180-gsdk5x3e	120	1	It	-PRON-	PRP
cord-002180-gsdk5x3e	120	2	was	be	VBD
cord-002180-gsdk5x3e	120	3	hypothesized	hypothesize	VBN
cord-002180-gsdk5x3e	120	4	that	that	IN
cord-002180-gsdk5x3e	120	5	the	the	DT
cord-002180-gsdk5x3e	120	6	manipulation	manipulation	NN
cord-002180-gsdk5x3e	120	7	of	of	IN
cord-002180-gsdk5x3e	120	8	the	the	DT
cord-002180-gsdk5x3e	120	9	host	host	NN
cord-002180-gsdk5x3e	120	10	cell	cell	NN
cord-002180-gsdk5x3e	120	11	cycle	cycle	NN
cord-002180-gsdk5x3e	120	12	by	by	IN
cord-002180-gsdk5x3e	120	13	NS5	NS5	NNP
cord-002180-gsdk5x3e	120	14	could	could	MD
cord-002180-gsdk5x3e	120	15	be	be	VB
cord-002180-gsdk5x3e	120	16	driven	drive	VBN
cord-002180-gsdk5x3e	120	17	by	by	IN
cord-002180-gsdk5x3e	120	18	its	-PRON-	PRP$
cord-002180-gsdk5x3e	120	19	association	association	NN
cord-002180-gsdk5x3e	120	20	with	with	IN
cord-002180-gsdk5x3e	120	21	host	host	NN
cord-002180-gsdk5x3e	120	22	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	120	23	initiation	initiation	NN
cord-002180-gsdk5x3e	120	24	factor	factor	NN
cord-002180-gsdk5x3e	120	25	eIF4	eif4	IN
cord-002180-gsdk5x3e	120	26	G	G	NNP
cord-002180-gsdk5x3e	120	27	,	,	,
cord-002180-gsdk5x3e	120	28	leading	lead	VBG
cord-002180-gsdk5x3e	120	29	to	to	IN
cord-002180-gsdk5x3e	120	30	inhibition	inhibition	NN
cord-002180-gsdk5x3e	120	31	of	of	IN
cord-002180-gsdk5x3e	120	32	host	host	NN
cord-002180-gsdk5x3e	120	33	translation	translation	NN
cord-002180-gsdk5x3e	120	34	,	,	,
cord-002180-gsdk5x3e	120	35	as	as	IN
cord-002180-gsdk5x3e	120	36	seen	see	VBN
cord-002180-gsdk5x3e	120	37	with	with	IN
cord-002180-gsdk5x3e	120	38	plant	plant	NN
cord-002180-gsdk5x3e	120	39	VPg	VPg	NNS
cord-002180-gsdk5x3e	120	40	proteins	protein	NNS
cord-002180-gsdk5x3e	120	41	[	[	-LRB-
cord-002180-gsdk5x3e	120	42	34	34	CD
cord-002180-gsdk5x3e	120	43	]	]	-RRB-
cord-002180-gsdk5x3e	120	44	,	,	,
cord-002180-gsdk5x3e	120	45	and	and	CC
cord-002180-gsdk5x3e	120	46	thus	thus	RB
cord-002180-gsdk5x3e	120	47	potentially	potentially	RB
cord-002180-gsdk5x3e	120	48	inducing	induce	VBG
cord-002180-gsdk5x3e	120	49	a	a	DT
cord-002180-gsdk5x3e	120	50	cell	cell	NN
cord-002180-gsdk5x3e	120	51	cycle	cycle	NN
cord-002180-gsdk5x3e	120	52	arrest	arrest	NN
cord-002180-gsdk5x3e	120	53	.	.	.
cord-002180-gsdk5x3e	121	1	The	the	DT
cord-002180-gsdk5x3e	121	2	ability	ability	NN
cord-002180-gsdk5x3e	121	3	of	of	IN
cord-002180-gsdk5x3e	121	4	MNV	mnv	NN
cord-002180-gsdk5x3e	121	5	NS5	ns5	JJ
cord-002180-gsdk5x3e	121	6	to	to	TO
cord-002180-gsdk5x3e	121	7	bind	bind	VB
cord-002180-gsdk5x3e	121	8	to	to	IN
cord-002180-gsdk5x3e	121	9	eIF4	eIF4	NNP
cord-002180-gsdk5x3e	121	10	G	g	NN
cord-002180-gsdk5x3e	121	11	can	can	MD
cord-002180-gsdk5x3e	121	12	be	be	VB
cord-002180-gsdk5x3e	121	13	abolished	abolish	VBN
cord-002180-gsdk5x3e	121	14	through	through	IN
cord-002180-gsdk5x3e	121	15	the	the	DT
cord-002180-gsdk5x3e	121	16	introduction	introduction	NN
cord-002180-gsdk5x3e	121	17	of	of	IN
cord-002180-gsdk5x3e	121	18	a	a	DT
cord-002180-gsdk5x3e	121	19	phenylalanine	phenylalanine	NN
cord-002180-gsdk5x3e	121	20	to	to	IN
cord-002180-gsdk5x3e	121	21	alanine	alanine	JJ
cord-002180-gsdk5x3e	121	22	substitution	substitution	NN
cord-002180-gsdk5x3e	121	23	at	at	IN
cord-002180-gsdk5x3e	121	24	position	position	NN
cord-002180-gsdk5x3e	121	25	123	123	CD
cord-002180-gsdk5x3e	121	26	(	(	-LRB-
cord-002180-gsdk5x3e	121	27	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	121	28	)	)	-RRB-
cord-002180-gsdk5x3e	121	29	)	)	-RRB-
cord-002180-gsdk5x3e	122	1	[	[	-LRB-
cord-002180-gsdk5x3e	122	2	30	30	CD
cord-002180-gsdk5x3e	122	3	]	]	-RRB-
cord-002180-gsdk5x3e	122	4	.	.	.
cord-002180-gsdk5x3e	123	1	Not	not	RB
cord-002180-gsdk5x3e	123	2	only	only	RB
cord-002180-gsdk5x3e	123	3	does	do	VBZ
cord-002180-gsdk5x3e	123	4	the	the	DT
cord-002180-gsdk5x3e	123	5	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	123	6	)	)	-RRB-
cord-002180-gsdk5x3e	123	7	substitution	substitution	NN
cord-002180-gsdk5x3e	123	8	inhibit	inhibit	NN
cord-002180-gsdk5x3e	123	9	binding	bind	VBG
cord-002180-gsdk5x3e	123	10	to	to	IN
cord-002180-gsdk5x3e	123	11	scaffold	scaffold	NN
cord-002180-gsdk5x3e	123	12	protein	protein	NN
cord-002180-gsdk5x3e	123	13	eIF4	eif4	IN
cord-002180-gsdk5x3e	123	14	G	G	NNP
cord-002180-gsdk5x3e	123	15	,	,	,
cord-002180-gsdk5x3e	123	16	it	-PRON-	PRP
cord-002180-gsdk5x3e	123	17	abolishes	abolish	VBZ
cord-002180-gsdk5x3e	123	18	viral	viral	JJ
cord-002180-gsdk5x3e	123	19	replication	replication	NN
cord-002180-gsdk5x3e	123	20	.	.	.
cord-002180-gsdk5x3e	124	1	We	-PRON-	PRP
cord-002180-gsdk5x3e	124	2	predicted	predict	VBD
cord-002180-gsdk5x3e	124	3	that	that	IN
cord-002180-gsdk5x3e	124	4	the	the	DT
cord-002180-gsdk5x3e	124	5	introduction	introduction	NN
cord-002180-gsdk5x3e	124	6	of	of	IN
cord-002180-gsdk5x3e	124	7	the	the	DT
cord-002180-gsdk5x3e	124	8	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	124	9	)	)	-RRB-
cord-002180-gsdk5x3e	124	10	substitution	substitution	NN
cord-002180-gsdk5x3e	124	11	could	could	MD
cord-002180-gsdk5x3e	124	12	inhibit	inhibit	VB
cord-002180-gsdk5x3e	124	13	its	-PRON-	PRP$
cord-002180-gsdk5x3e	124	14	cell	cell	NN
cord-002180-gsdk5x3e	124	15	cycle	cycle	NN
cord-002180-gsdk5x3e	124	16	control	control	NN
cord-002180-gsdk5x3e	124	17	.	.	.
cord-002180-gsdk5x3e	125	1	RNA	RNA	NNP
cord-002180-gsdk5x3e	125	2	transcripts	transcript	NNS
cord-002180-gsdk5x3e	125	3	encoding	encode	VBG
cord-002180-gsdk5x3e	125	4	WT	WT	NNP
cord-002180-gsdk5x3e	125	5	NS5	ns5	JJ
cord-002180-gsdk5x3e	125	6	,	,	,
cord-002180-gsdk5x3e	125	7	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	125	8	)	)	-RRB-
cord-002180-gsdk5x3e	125	9	and	and	CC
cord-002180-gsdk5x3e	125	10	NS1	ns1	NN
cord-002180-gsdk5x3e	125	11	-	-	HYPH
cord-002180-gsdk5x3e	125	12	2	2	CD
cord-002180-gsdk5x3e	125	13	were	be	VBD
cord-002180-gsdk5x3e	125	14	generated	generate	VBN
cord-002180-gsdk5x3e	125	15	,	,	,
cord-002180-gsdk5x3e	125	16	transfected	transfecte	VBN
cord-002180-gsdk5x3e	125	17	into	into	IN
cord-002180-gsdk5x3e	125	18	an	an	DT
cord-002180-gsdk5x3e	125	19	asynchronous	asynchronous	JJ
cord-002180-gsdk5x3e	125	20	cell	cell	NN
cord-002180-gsdk5x3e	125	21	population	population	NN
cord-002180-gsdk5x3e	125	22	and	and	CC
cord-002180-gsdk5x3e	125	23	their	-PRON-	PRP$
cord-002180-gsdk5x3e	125	24	cell	cell	NN
cord-002180-gsdk5x3e	125	25	cycle	cycle	NN
cord-002180-gsdk5x3e	125	26	effects	effect	NNS
cord-002180-gsdk5x3e	125	27	analyzed	analyze	VBN
cord-002180-gsdk5x3e	125	28	by	by	IN
cord-002180-gsdk5x3e	125	29	flow	flow	NN
cord-002180-gsdk5x3e	125	30	cytometry	cytometry	NN
cord-002180-gsdk5x3e	125	31	.	.	.
cord-002180-gsdk5x3e	126	1	Both	both	DT
cord-002180-gsdk5x3e	126	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	126	3	and	and	CC
cord-002180-gsdk5x3e	126	4	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	126	5	)	)	-RRB-
cord-002180-gsdk5x3e	126	6	could	could	MD
cord-002180-gsdk5x3e	126	7	be	be	VB
cord-002180-gsdk5x3e	126	8	detected	detect	VBN
cord-002180-gsdk5x3e	126	9	by	by	IN
cord-002180-gsdk5x3e	126	10	the	the	DT
cord-002180-gsdk5x3e	126	11	α	α	NN
cord-002180-gsdk5x3e	126	12	-	-	HYPH
cord-002180-gsdk5x3e	126	13	NS5	ns5	JJ
cord-002180-gsdk5x3e	126	14	antibody	antibody	NN
cord-002180-gsdk5x3e	126	15	(	(	-LRB-
cord-002180-gsdk5x3e	126	16	Fig	Fig	NNP
cord-002180-gsdk5x3e	126	17	3C	3C	NNP
cord-002180-gsdk5x3e	126	18	)	)	-RRB-
cord-002180-gsdk5x3e	126	19	.	.	.
cord-002180-gsdk5x3e	127	1	Expression	expression	NN
cord-002180-gsdk5x3e	127	2	of	of	IN
cord-002180-gsdk5x3e	127	3	viral	viral	JJ
cord-002180-gsdk5x3e	127	4	NS1	ns1	NN
cord-002180-gsdk5x3e	127	5	-	-	HYPH
cord-002180-gsdk5x3e	127	6	2	2	CD
cord-002180-gsdk5x3e	127	7	had	have	VBD
cord-002180-gsdk5x3e	127	8	no	no	DT
cord-002180-gsdk5x3e	127	9	effect	effect	NN
cord-002180-gsdk5x3e	127	10	on	on	IN
cord-002180-gsdk5x3e	127	11	the	the	DT
cord-002180-gsdk5x3e	127	12	host	host	NN
cord-002180-gsdk5x3e	127	13	cell	cell	NN
cord-002180-gsdk5x3e	127	14	cycle	cycle	NN
cord-002180-gsdk5x3e	127	15	while	while	IN
cord-002180-gsdk5x3e	127	16	expression	expression	NN
cord-002180-gsdk5x3e	127	17	of	of	IN
cord-002180-gsdk5x3e	127	18	both	both	CC
cord-002180-gsdk5x3e	127	19	NS5	ns5	JJ
cord-002180-gsdk5x3e	127	20	and	and	CC
cord-002180-gsdk5x3e	127	21	the	the	DT
cord-002180-gsdk5x3e	127	22	NS5(F123A	NS5(F123A	NNPS
cord-002180-gsdk5x3e	127	23	)	)	-RRB-
cord-002180-gsdk5x3e	128	1	variant	variant	NN
cord-002180-gsdk5x3e	128	2	increased	increase	VBD
cord-002180-gsdk5x3e	128	3	the	the	DT
cord-002180-gsdk5x3e	128	4	G	g	NN
cord-002180-gsdk5x3e	128	5	0	0	CD
cord-002180-gsdk5x3e	128	6	/G	/g	SYM
cord-002180-gsdk5x3e	128	7	1	1	CD
cord-002180-gsdk5x3e	128	8	population	population	NN
cord-002180-gsdk5x3e	128	9	by~22	by~22	NNP
cord-002180-gsdk5x3e	128	10	%	%	NN
cord-002180-gsdk5x3e	128	11	and	and	CC
cord-002180-gsdk5x3e	128	12	decreased	decrease	VBD
cord-002180-gsdk5x3e	128	13	the	the	DT
cord-002180-gsdk5x3e	128	14	S	s	NN
cord-002180-gsdk5x3e	128	15	phase	phase	NN
cord-002180-gsdk5x3e	128	16	population	population	NN
cord-002180-gsdk5x3e	128	17	proportionally	proportionally	RB
cord-002180-gsdk5x3e	128	18	when	when	WRB
cord-002180-gsdk5x3e	128	19	compared	compare	VBN
cord-002180-gsdk5x3e	128	20	to	to	IN
cord-002180-gsdk5x3e	128	21	the	the	DT
cord-002180-gsdk5x3e	128	22	mock	mock	NN
cord-002180-gsdk5x3e	128	23	-	-	HYPH
cord-002180-gsdk5x3e	128	24	transfected	transfecte	VBN
cord-002180-gsdk5x3e	128	25	population	population	NN
cord-002180-gsdk5x3e	128	26	(	(	-LRB-
cord-002180-gsdk5x3e	128	27	Fig	Fig	NNP
cord-002180-gsdk5x3e	128	28	3B	3b	CD
cord-002180-gsdk5x3e	128	29	)	)	-RRB-
cord-002180-gsdk5x3e	128	30	.	.	.
cord-002180-gsdk5x3e	129	1	Furthermore	furthermore	RB
cord-002180-gsdk5x3e	129	2	,	,	,
cord-002180-gsdk5x3e	129	3	the	the	DT
cord-002180-gsdk5x3e	129	4	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	129	5	)	)	-RRB-
cord-002180-gsdk5x3e	129	6	variant	variant	NN
cord-002180-gsdk5x3e	129	7	decreased	decrease	VBD
cord-002180-gsdk5x3e	129	8	cyclin	cyclin	NN
cord-002180-gsdk5x3e	129	9	A	a	DT
cord-002180-gsdk5x3e	129	10	protein	protein	NN
cord-002180-gsdk5x3e	129	11	expression	expression	NN
cord-002180-gsdk5x3e	129	12	by	by	IN
cord-002180-gsdk5x3e	129	13	67	67	CD
cord-002180-gsdk5x3e	129	14	%	%	NN
cord-002180-gsdk5x3e	129	15	when	when	WRB
cord-002180-gsdk5x3e	129	16	compared	compare	VBN
cord-002180-gsdk5x3e	129	17	to	to	IN
cord-002180-gsdk5x3e	129	18	the	the	DT
cord-002180-gsdk5x3e	129	19	mocktransfected	mocktransfecte	VBN
cord-002180-gsdk5x3e	129	20	population	population	NN
cord-002180-gsdk5x3e	129	21	in	in	IN
cord-002180-gsdk5x3e	129	22	a	a	DT
cord-002180-gsdk5x3e	129	23	synonymous	synonymous	JJ
cord-002180-gsdk5x3e	129	24	manner	manner	NN
cord-002180-gsdk5x3e	129	25	to	to	IN
cord-002180-gsdk5x3e	129	26	NS5	NS5	NNP
cord-002180-gsdk5x3e	129	27	,	,	,
cord-002180-gsdk5x3e	129	28	strongly	strongly	RB
cord-002180-gsdk5x3e	129	29	implying	imply	VBG
cord-002180-gsdk5x3e	129	30	that	that	IN
cord-002180-gsdk5x3e	129	31	the	the	DT
cord-002180-gsdk5x3e	129	32	host	host	NN
cord-002180-gsdk5x3e	129	33	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	129	34	initiation	initiation	NN
cord-002180-gsdk5x3e	129	35	factor	factor	NN
cord-002180-gsdk5x3e	129	36	binding	bind	VBG
cord-002180-gsdk5x3e	129	37	domain	domain	NN
cord-002180-gsdk5x3e	129	38	of	of	IN
cord-002180-gsdk5x3e	129	39	NS5	NS5	NNP
cord-002180-gsdk5x3e	129	40	does	do	VBZ
cord-002180-gsdk5x3e	129	41	not	not	RB
cord-002180-gsdk5x3e	129	42	play	play	VB
cord-002180-gsdk5x3e	129	43	a	a	DT
cord-002180-gsdk5x3e	129	44	role	role	NN
cord-002180-gsdk5x3e	129	45	in	in	IN
cord-002180-gsdk5x3e	129	46	its	-PRON-	PRP$
cord-002180-gsdk5x3e	129	47	cell	cell	NN
cord-002180-gsdk5x3e	129	48	cycle	cycle	NN
cord-002180-gsdk5x3e	129	49	manipulation	manipulation	NN
cord-002180-gsdk5x3e	129	50	(	(	-LRB-
cord-002180-gsdk5x3e	129	51	Fig	Fig	NNP
cord-002180-gsdk5x3e	129	52	3D	3d	NN
cord-002180-gsdk5x3e	129	53	)	)	-RRB-
cord-002180-gsdk5x3e	129	54	.	.	.
cord-002180-gsdk5x3e	130	1	The	the	DT
cord-002180-gsdk5x3e	130	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	130	3	protein	protein	NN
cord-002180-gsdk5x3e	130	4	from	from	IN
cord-002180-gsdk5x3e	130	5	MNV	MNV	NNP
cord-002180-gsdk5x3e	130	6	is	be	VBZ
cord-002180-gsdk5x3e	130	7	covalently	covalently	RB
cord-002180-gsdk5x3e	130	8	attached	attach	VBN
cord-002180-gsdk5x3e	130	9	at	at	IN
cord-002180-gsdk5x3e	130	10	the	the	DT
cord-002180-gsdk5x3e	130	11	5	5	CD
cord-002180-gsdk5x3e	130	12	0	0	CD
cord-002180-gsdk5x3e	130	13	terminus	terminus	NN
cord-002180-gsdk5x3e	130	14	of	of	IN
cord-002180-gsdk5x3e	130	15	viral	viral	JJ
cord-002180-gsdk5x3e	130	16	RNA	RNA	NNP
cord-002180-gsdk5x3e	130	17	,	,	,
cord-002180-gsdk5x3e	130	18	acting	act	VBG
cord-002180-gsdk5x3e	130	19	as	as	IN
cord-002180-gsdk5x3e	130	20	a	a	DT
cord-002180-gsdk5x3e	130	21	cap	cap	NN
cord-002180-gsdk5x3e	130	22	to	to	IN
cord-002180-gsdk5x3e	130	23	prime	prime	NNP
cord-002180-gsdk5x3e	130	24	RNA	RNA	NNP
cord-002180-gsdk5x3e	130	25	synthesis	synthesis	NN
cord-002180-gsdk5x3e	130	26	[	[	-LRB-
cord-002180-gsdk5x3e	130	27	8	8	CD
cord-002180-gsdk5x3e	130	28	]	]	-RRB-
cord-002180-gsdk5x3e	130	29	.	.	.
cord-002180-gsdk5x3e	131	1	Attachment	attachment	NN
cord-002180-gsdk5x3e	131	2	of	of	IN
cord-002180-gsdk5x3e	131	3	NS5	NS5	NNP
cord-002180-gsdk5x3e	131	4	to	to	IN
cord-002180-gsdk5x3e	131	5	viral	viral	JJ
cord-002180-gsdk5x3e	131	6	RNA	RNA	NNP
cord-002180-gsdk5x3e	131	7	occurs	occur	VBZ
cord-002180-gsdk5x3e	131	8	via	via	IN
cord-002180-gsdk5x3e	131	9	the	the	DT
cord-002180-gsdk5x3e	131	10	tyrosine	tyrosine	NN
cord-002180-gsdk5x3e	131	11	residue	residue	NN
cord-002180-gsdk5x3e	131	12	at	at	IN
cord-002180-gsdk5x3e	131	13	position	position	NN
cord-002180-gsdk5x3e	131	14	26	26	CD
cord-002180-gsdk5x3e	131	15	(	(	-LRB-
cord-002180-gsdk5x3e	131	16	Y26	Y26	NNP
cord-002180-gsdk5x3e	131	17	)	)	-RRB-
cord-002180-gsdk5x3e	131	18	in	in	IN
cord-002180-gsdk5x3e	131	19	MNV	MNV	NNP
cord-002180-gsdk5x3e	131	20	,	,	,
cord-002180-gsdk5x3e	131	21	lying	lie	VBG
cord-002180-gsdk5x3e	131	22	within	within	IN
cord-002180-gsdk5x3e	131	23	a	a	DT
cord-002180-gsdk5x3e	131	24	highly	highly	RB
cord-002180-gsdk5x3e	131	25	conserved	conserve	VBN
cord-002180-gsdk5x3e	131	26	EYDE	EYDE	NNP
cord-002180-gsdk5x3e	131	27	motif	motif	NN
cord-002180-gsdk5x3e	131	28	in	in	IN
cord-002180-gsdk5x3e	131	29	caliciviruses	caliciviruse	NNS
cord-002180-gsdk5x3e	131	30	[	[	-LRB-
cord-002180-gsdk5x3e	131	31	10	10	CD
cord-002180-gsdk5x3e	131	32	,	,	,
cord-002180-gsdk5x3e	131	33	35	35	CD
cord-002180-gsdk5x3e	131	34	,	,	,
cord-002180-gsdk5x3e	131	35	36	36	CD
cord-002180-gsdk5x3e	131	36	]	]	-RRB-
cord-002180-gsdk5x3e	131	37	.	.	.
cord-002180-gsdk5x3e	132	1	Substitution	substitution	NN
cord-002180-gsdk5x3e	132	2	of	of	IN
cord-002180-gsdk5x3e	132	3	the	the	DT
cord-002180-gsdk5x3e	132	4	Y26	Y26	NNP
cord-002180-gsdk5x3e	132	5	residue	residue	NN
cord-002180-gsdk5x3e	132	6	with	with	IN
cord-002180-gsdk5x3e	132	7	an	an	DT
cord-002180-gsdk5x3e	132	8	alanine	alanine	JJ
cord-002180-gsdk5x3e	132	9	residue	residue	NN
cord-002180-gsdk5x3e	132	10	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	132	11	)	)	-RRB-
cord-002180-gsdk5x3e	132	12	prevents	prevent	VBZ
cord-002180-gsdk5x3e	132	13	the	the	DT
cord-002180-gsdk5x3e	132	14	formation	formation	NN
cord-002180-gsdk5x3e	132	15	of	of	IN
cord-002180-gsdk5x3e	132	16	NS5-viral	NS5-viral	NNP
cord-002180-gsdk5x3e	132	17	RNA	RNA	NNP
cord-002180-gsdk5x3e	132	18	[	[	-LRB-
cord-002180-gsdk5x3e	132	19	10	10	CD
cord-002180-gsdk5x3e	132	20	,	,	,
cord-002180-gsdk5x3e	132	21	37	37	CD
cord-002180-gsdk5x3e	132	22	]	]	-RRB-
cord-002180-gsdk5x3e	132	23	.	.	.
cord-002180-gsdk5x3e	133	1	The	the	DT
cord-002180-gsdk5x3e	133	2	nucleotidylation	nucleotidylation	NN
cord-002180-gsdk5x3e	133	3	of	of	IN
cord-002180-gsdk5x3e	133	4	NS5	NS5	NNP
cord-002180-gsdk5x3e	133	5	at	at	IN
cord-002180-gsdk5x3e	133	6	Y26	Y26	NNP
cord-002180-gsdk5x3e	133	7	is	be	VBZ
cord-002180-gsdk5x3e	133	8	likely	likely	RB
cord-002180-gsdk5x3e	133	9	contingent	contingent	JJ
cord-002180-gsdk5x3e	133	10	upon	upon	IN
cord-002180-gsdk5x3e	133	11	viral	viral	JJ
cord-002180-gsdk5x3e	133	12	RNA	rna	NN
cord-002180-gsdk5x3e	133	13	polymerase	polymerase	NN
cord-002180-gsdk5x3e	133	14	(	(	-LRB-
cord-002180-gsdk5x3e	133	15	NS7	NS7	NNP
cord-002180-gsdk5x3e	133	16	)	)	-RRB-
cord-002180-gsdk5x3e	133	17	,	,	,
cord-002180-gsdk5x3e	133	18	which	which	WDT
cord-002180-gsdk5x3e	133	19	is	be	VBZ
cord-002180-gsdk5x3e	133	20	not	not	RB
cord-002180-gsdk5x3e	133	21	present	present	JJ
cord-002180-gsdk5x3e	133	22	in	in	IN
cord-002180-gsdk5x3e	133	23	the	the	DT
cord-002180-gsdk5x3e	133	24	expression	expression	NN
cord-002180-gsdk5x3e	133	25	system	system	NN
cord-002180-gsdk5x3e	133	26	used	use	VBN
cord-002180-gsdk5x3e	133	27	in	in	IN
cord-002180-gsdk5x3e	133	28	this	this	DT
cord-002180-gsdk5x3e	133	29	study	study	NN
cord-002180-gsdk5x3e	133	30	.	.	.
cord-002180-gsdk5x3e	134	1	To	to	TO
cord-002180-gsdk5x3e	134	2	further	further	RB
cord-002180-gsdk5x3e	134	3	confirm	confirm	VB
cord-002180-gsdk5x3e	134	4	that	that	IN
cord-002180-gsdk5x3e	134	5	Y26	Y26	NNP
cord-002180-gsdk5x3e	134	6	residue	residue	NN
cord-002180-gsdk5x3e	134	7	is	be	VBZ
cord-002180-gsdk5x3e	134	8	not	not	RB
cord-002180-gsdk5x3e	134	9	involved	involve	VBN
cord-002180-gsdk5x3e	134	10	in	in	IN
cord-002180-gsdk5x3e	134	11	the	the	DT
cord-002180-gsdk5x3e	134	12	cell	cell	NN
cord-002180-gsdk5x3e	134	13	cycle	cycle	NN
cord-002180-gsdk5x3e	134	14	arrest	arrest	NN
cord-002180-gsdk5x3e	134	15	through	through	IN
cord-002180-gsdk5x3e	134	16	an	an	DT
cord-002180-gsdk5x3e	134	17	unidentified	unidentified	JJ
cord-002180-gsdk5x3e	134	18	mechanism	mechanism	NN
cord-002180-gsdk5x3e	134	19	,	,	,
cord-002180-gsdk5x3e	134	20	an	an	DT
cord-002180-gsdk5x3e	134	21	alanine	alanine	JJ
cord-002180-gsdk5x3e	134	22	substitution	substitution	NN
cord-002180-gsdk5x3e	134	23	at	at	IN
cord-002180-gsdk5x3e	134	24	Y26	Y26	NNP
cord-002180-gsdk5x3e	134	25	was	be	VBD
cord-002180-gsdk5x3e	134	26	introduced	introduce	VBN
cord-002180-gsdk5x3e	134	27	(	(	-LRB-
cord-002180-gsdk5x3e	134	28	NS5	ns5	JJ
cord-002180-gsdk5x3e	134	29	(	(	-LRB-
cord-002180-gsdk5x3e	134	30	Y26	Y26	NNP
cord-002180-gsdk5x3e	134	31	)	)	-RRB-
cord-002180-gsdk5x3e	134	32	)	)	-RRB-
cord-002180-gsdk5x3e	134	33	.	.	.
cord-002180-gsdk5x3e	135	1	Although	although	IN
cord-002180-gsdk5x3e	135	2	the	the	DT
cord-002180-gsdk5x3e	135	3	viral	viral	JJ
cord-002180-gsdk5x3e	135	4	genome	genome	NN
cord-002180-gsdk5x3e	135	5	and	and	CC
cord-002180-gsdk5x3e	135	6	NS7	NS7	NNP
cord-002180-gsdk5x3e	135	7	protein	protein	NN
cord-002180-gsdk5x3e	135	8	is	be	VBZ
cord-002180-gsdk5x3e	135	9	absent	absent	JJ
cord-002180-gsdk5x3e	135	10	in	in	IN
cord-002180-gsdk5x3e	135	11	the	the	DT
cord-002180-gsdk5x3e	135	12	transfection	transfection	NN
cord-002180-gsdk5x3e	135	13	,	,	,
cord-002180-gsdk5x3e	135	14	we	-PRON-	PRP
cord-002180-gsdk5x3e	135	15	could	could	MD
cord-002180-gsdk5x3e	135	16	not	not	RB
cord-002180-gsdk5x3e	135	17	exclude	exclude	VB
cord-002180-gsdk5x3e	135	18	that	that	IN
cord-002180-gsdk5x3e	135	19	NS5	NS5	NNP
cord-002180-gsdk5x3e	135	20	could	could	MD
cord-002180-gsdk5x3e	135	21	be	be	VB
cord-002180-gsdk5x3e	135	22	attaching	attach	VBG
cord-002180-gsdk5x3e	135	23	via	via	IN
cord-002180-gsdk5x3e	135	24	the	the	DT
cord-002180-gsdk5x3e	135	25	Y26	Y26	NNP
cord-002180-gsdk5x3e	135	26	residue	residue	NN
cord-002180-gsdk5x3e	135	27	to	to	TO
cord-002180-gsdk5x3e	135	28	host	host	VB
cord-002180-gsdk5x3e	135	29	RNA	RNA	NNP
cord-002180-gsdk5x3e	135	30	.	.	.
cord-002180-gsdk5x3e	136	1	RNA	RNA	NNP
cord-002180-gsdk5x3e	136	2	encoding	encode	VBG
cord-002180-gsdk5x3e	136	3	WT	WT	NNP
cord-002180-gsdk5x3e	136	4	NS5	NS5	NNP
cord-002180-gsdk5x3e	136	5	,	,	,
cord-002180-gsdk5x3e	136	6	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	136	7	)	)	-RRB-
cord-002180-gsdk5x3e	136	8	and	and	CC
cord-002180-gsdk5x3e	136	9	NS1	ns1	NN
cord-002180-gsdk5x3e	136	10	-	-	HYPH
cord-002180-gsdk5x3e	136	11	2	2	CD
cord-002180-gsdk5x3e	136	12	were	be	VBD
cord-002180-gsdk5x3e	136	13	synthesized	synthesize	VBN
cord-002180-gsdk5x3e	136	14	,	,	,
cord-002180-gsdk5x3e	136	15	transfected	transfecte	VBN
cord-002180-gsdk5x3e	136	16	into	into	IN
cord-002180-gsdk5x3e	136	17	an	an	DT
cord-002180-gsdk5x3e	136	18	asynchronous	asynchronous	JJ
cord-002180-gsdk5x3e	136	19	cell	cell	NN
cord-002180-gsdk5x3e	136	20	population	population	NN
cord-002180-gsdk5x3e	136	21	and	and	CC
cord-002180-gsdk5x3e	136	22	their	-PRON-	PRP$
cord-002180-gsdk5x3e	136	23	cell	cell	NN
cord-002180-gsdk5x3e	136	24	cycle	cycle	NN
cord-002180-gsdk5x3e	136	25	effects	effect	NNS
cord-002180-gsdk5x3e	136	26	analyzed	analyze	VBN
cord-002180-gsdk5x3e	136	27	by	by	IN
cord-002180-gsdk5x3e	136	28	flow	flow	NN
cord-002180-gsdk5x3e	136	29	cytometry	cytometry	NN
cord-002180-gsdk5x3e	136	30	.	.	.
cord-002180-gsdk5x3e	137	1	Both	both	DT
cord-002180-gsdk5x3e	137	2	NS5	NS5	NNP
cord-002180-gsdk5x3e	137	3	and	and	CC
cord-002180-gsdk5x3e	137	4	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	137	5	)	)	-RRB-
cord-002180-gsdk5x3e	137	6	could	could	MD
cord-002180-gsdk5x3e	137	7	be	be	VB
cord-002180-gsdk5x3e	137	8	detected	detect	VBN
cord-002180-gsdk5x3e	137	9	by	by	IN
cord-002180-gsdk5x3e	137	10	the	the	DT
cord-002180-gsdk5x3e	137	11	α	α	NN
cord-002180-gsdk5x3e	137	12	-	-	HYPH
cord-002180-gsdk5x3e	137	13	NS5	ns5	JJ
cord-002180-gsdk5x3e	137	14	antibody	antibody	NN
cord-002180-gsdk5x3e	137	15	(	(	-LRB-
cord-002180-gsdk5x3e	137	16	Fig	Fig	NNP
cord-002180-gsdk5x3e	137	17	4C	4c	CD
cord-002180-gsdk5x3e	137	18	)	)	-RRB-
cord-002180-gsdk5x3e	137	19	.	.	.
cord-002180-gsdk5x3e	138	1	Expression	expression	NN
cord-002180-gsdk5x3e	138	2	of	of	IN
cord-002180-gsdk5x3e	138	3	viral	viral	JJ
cord-002180-gsdk5x3e	138	4	NS1	ns1	NN
cord-002180-gsdk5x3e	138	5	-	-	HYPH
cord-002180-gsdk5x3e	138	6	2	2	CD
cord-002180-gsdk5x3e	138	7	had	have	VBD
cord-002180-gsdk5x3e	138	8	no	no	DT
cord-002180-gsdk5x3e	138	9	effect	effect	NN
cord-002180-gsdk5x3e	138	10	on	on	IN
cord-002180-gsdk5x3e	138	11	the	the	DT
cord-002180-gsdk5x3e	138	12	host	host	NN
cord-002180-gsdk5x3e	138	13	cell	cell	NN
cord-002180-gsdk5x3e	138	14	cycle	cycle	NN
cord-002180-gsdk5x3e	138	15	while	while	IN
cord-002180-gsdk5x3e	138	16	both	both	CC
cord-002180-gsdk5x3e	138	17	NS5	NS5	NNP
cord-002180-gsdk5x3e	138	18	and	and	CC
cord-002180-gsdk5x3e	138	19	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	138	20	)	)	-RRB-
cord-002180-gsdk5x3e	138	21	expression	expression	NN
cord-002180-gsdk5x3e	138	22	increased	increase	VBD
cord-002180-gsdk5x3e	138	23	the	the	DT
cord-002180-gsdk5x3e	138	24	G	g	NN
cord-002180-gsdk5x3e	138	25	0	0	CD
cord-002180-gsdk5x3e	138	26	/G	/g	SYM
cord-002180-gsdk5x3e	138	27	1	1	CD
cord-002180-gsdk5x3e	138	28	population	population	NN
cord-002180-gsdk5x3e	138	29	by~20	by~20	NNP
cord-002180-gsdk5x3e	138	30	%	%	NN
cord-002180-gsdk5x3e	138	31	and	and	CC
cord-002180-gsdk5x3e	138	32	decreased	decrease	VBD
cord-002180-gsdk5x3e	138	33	the	the	DT
cord-002180-gsdk5x3e	138	34	S	s	NN
cord-002180-gsdk5x3e	138	35	phase	phase	NN
cord-002180-gsdk5x3e	138	36	population	population	NN
cord-002180-gsdk5x3e	138	37	proportionally	proportionally	RB
cord-002180-gsdk5x3e	138	38	when	when	WRB
cord-002180-gsdk5x3e	138	39	compared	compare	VBN
cord-002180-gsdk5x3e	138	40	to	to	IN
cord-002180-gsdk5x3e	138	41	the	the	DT
cord-002180-gsdk5x3e	138	42	mock	mock	NN
cord-002180-gsdk5x3e	138	43	-	-	HYPH
cord-002180-gsdk5x3e	138	44	transfected	transfecte	VBN
cord-002180-gsdk5x3e	138	45	population	population	NN
cord-002180-gsdk5x3e	138	46	(	(	-LRB-
cord-002180-gsdk5x3e	138	47	Fig	Fig	NNP
cord-002180-gsdk5x3e	138	48	4B	4b	CD
cord-002180-gsdk5x3e	138	49	)	)	-RRB-
cord-002180-gsdk5x3e	138	50	.	.	.
cord-002180-gsdk5x3e	139	1	Furthermore	furthermore	RB
cord-002180-gsdk5x3e	139	2	,	,	,
cord-002180-gsdk5x3e	139	3	WT	WT	NNP
cord-002180-gsdk5x3e	139	4	NS5	NS5	NNP
cord-002180-gsdk5x3e	139	5	and	and	CC
cord-002180-gsdk5x3e	139	6	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	139	7	)	)	-RRB-
cord-002180-gsdk5x3e	139	8	decreased	decrease	VBD
cord-002180-gsdk5x3e	139	9	cyclin	cyclin	NN
cord-002180-gsdk5x3e	139	10	A	a	DT
cord-002180-gsdk5x3e	139	11	protein	protein	NN
cord-002180-gsdk5x3e	139	12	expression	expression	NN
cord-002180-gsdk5x3e	139	13	by	by	IN
cord-002180-gsdk5x3e	139	14	69	69	CD
cord-002180-gsdk5x3e	139	15	%	%	NN
cord-002180-gsdk5x3e	139	16	and	and	CC
cord-002180-gsdk5x3e	139	17	73	73	CD
cord-002180-gsdk5x3e	139	18	%	%	NN
cord-002180-gsdk5x3e	139	19	respectively	respectively	RB
cord-002180-gsdk5x3e	139	20	when	when	WRB
cord-002180-gsdk5x3e	139	21	compared	compare	VBN
cord-002180-gsdk5x3e	139	22	to	to	IN
cord-002180-gsdk5x3e	139	23	the	the	DT
cord-002180-gsdk5x3e	139	24	mock	mock	NN
cord-002180-gsdk5x3e	139	25	-	-	HYPH
cord-002180-gsdk5x3e	139	26	transfected	transfecte	VBN
cord-002180-gsdk5x3e	139	27	population	population	NN
cord-002180-gsdk5x3e	139	28	(	(	-LRB-
cord-002180-gsdk5x3e	139	29	Fig	Fig	NNP
cord-002180-gsdk5x3e	139	30	4D	4d	CD
cord-002180-gsdk5x3e	139	31	)	)	-RRB-
cord-002180-gsdk5x3e	139	32	.	.	.
cord-002180-gsdk5x3e	140	1	These	these	DT
cord-002180-gsdk5x3e	140	2	results	result	NNS
cord-002180-gsdk5x3e	140	3	,	,	,
cord-002180-gsdk5x3e	140	4	combined	combine	VBN
cord-002180-gsdk5x3e	140	5	with	with	IN
cord-002180-gsdk5x3e	140	6	the	the	DT
cord-002180-gsdk5x3e	140	7	absence	absence	NN
cord-002180-gsdk5x3e	140	8	of	of	IN
cord-002180-gsdk5x3e	140	9	viral	viral	JJ
cord-002180-gsdk5x3e	140	10	RNA	RNA	NNP
cord-002180-gsdk5x3e	140	11	polymerase	polymerase	NN
cord-002180-gsdk5x3e	140	12	,	,	,
cord-002180-gsdk5x3e	140	13	imply	imply	VBP
cord-002180-gsdk5x3e	140	14	that	that	IN
cord-002180-gsdk5x3e	140	15	nucleotidylation	nucleotidylation	NN
cord-002180-gsdk5x3e	140	16	to	to	IN
cord-002180-gsdk5x3e	140	17	RNA	RNA	NNP
cord-002180-gsdk5x3e	140	18	via	via	IN
cord-002180-gsdk5x3e	140	19	the	the	DT
cord-002180-gsdk5x3e	140	20	Y26	Y26	NNP
cord-002180-gsdk5x3e	140	21	residue	residue	NN
cord-002180-gsdk5x3e	140	22	has	have	VBZ
cord-002180-gsdk5x3e	140	23	no	no	DT
cord-002180-gsdk5x3e	140	24	role	role	NN
cord-002180-gsdk5x3e	140	25	in	in	IN
cord-002180-gsdk5x3e	140	26	NS5	ns5	JJ
cord-002180-gsdk5x3e	140	27	ability	ability	NN
cord-002180-gsdk5x3e	140	28	to	to	TO
cord-002180-gsdk5x3e	140	29	manipulate	manipulate	VB
cord-002180-gsdk5x3e	140	30	the	the	DT
cord-002180-gsdk5x3e	140	31	host	host	NN
cord-002180-gsdk5x3e	140	32	cell	cell	NN
cord-002180-gsdk5x3e	140	33	cycle	cycle	NN
cord-002180-gsdk5x3e	140	34	.	.	.
cord-002180-gsdk5x3e	141	1	We	-PRON-	PRP
cord-002180-gsdk5x3e	141	2	recently	recently	RB
cord-002180-gsdk5x3e	141	3	identified	identify	VBD
cord-002180-gsdk5x3e	141	4	that	that	IN
cord-002180-gsdk5x3e	141	5	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	141	6	was	be	VBD
cord-002180-gsdk5x3e	141	7	able	able	JJ
cord-002180-gsdk5x3e	141	8	to	to	TO
cord-002180-gsdk5x3e	141	9	manipulate	manipulate	VB
cord-002180-gsdk5x3e	141	10	the	the	DT
cord-002180-gsdk5x3e	141	11	host	host	NN
cord-002180-gsdk5x3e	141	12	cell	cell	NN
cord-002180-gsdk5x3e	141	13	cycle	cycle	NN
cord-002180-gsdk5x3e	141	14	,	,	,
cord-002180-gsdk5x3e	141	15	causing	cause	VBG
cord-002180-gsdk5x3e	141	16	an	an	DT
cord-002180-gsdk5x3e	141	17	arrest	arrest	NN
cord-002180-gsdk5x3e	141	18	and	and	CC
cord-002180-gsdk5x3e	141	19	accumulation	accumulation	NN
cord-002180-gsdk5x3e	141	20	in	in	IN
cord-002180-gsdk5x3e	141	21	an	an	DT
cord-002180-gsdk5x3e	141	22	early	early	JJ
cord-002180-gsdk5x3e	141	23	cell	cell	NN
cord-002180-gsdk5x3e	141	24	growth	growth	NN
cord-002180-gsdk5x3e	141	25	phase	phase	NN
cord-002180-gsdk5x3e	141	26	leading	lead	VBG
cord-002180-gsdk5x3e	141	27	to	to	IN
cord-002180-gsdk5x3e	141	28	enhanced	enhance	VBN
cord-002180-gsdk5x3e	141	29	viral	viral	JJ
cord-002180-gsdk5x3e	141	30	replication	replication	NN
cord-002180-gsdk5x3e	141	31	[	[	-LRB-
cord-002180-gsdk5x3e	141	32	20	20	CD
cord-002180-gsdk5x3e	141	33	]	]	-RRB-
cord-002180-gsdk5x3e	141	34	.	.	.
cord-002180-gsdk5x3e	142	1	This	this	DT
cord-002180-gsdk5x3e	142	2	study	study	NN
cord-002180-gsdk5x3e	142	3	identifies	identify	VBZ
cord-002180-gsdk5x3e	142	4	that	that	IN
cord-002180-gsdk5x3e	142	5	the	the	DT
cord-002180-gsdk5x3e	142	6	NS5	ns5	JJ
cord-002180-gsdk5x3e	142	7	protein	protein	NN
cord-002180-gsdk5x3e	142	8	from	from	IN
cord-002180-gsdk5x3e	142	9	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	142	10	is	be	VBZ
cord-002180-gsdk5x3e	142	11	able	able	JJ
cord-002180-gsdk5x3e	142	12	to	to	TO
cord-002180-gsdk5x3e	142	13	induce	induce	VB
cord-002180-gsdk5x3e	142	14	a	a	DT
cord-002180-gsdk5x3e	142	15	cell	cell	NN
cord-002180-gsdk5x3e	142	16	cycle	cycle	NN
cord-002180-gsdk5x3e	142	17	arrest	arrest	NN
cord-002180-gsdk5x3e	142	18	analogous	analogous	JJ
cord-002180-gsdk5x3e	142	19	to	to	IN
cord-002180-gsdk5x3e	142	20	that	that	DT
cord-002180-gsdk5x3e	142	21	of	of	IN
cord-002180-gsdk5x3e	142	22	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	142	23	infection	infection	NN
cord-002180-gsdk5x3e	142	24	in	in	IN
cord-002180-gsdk5x3e	142	25	a	a	DT
cord-002180-gsdk5x3e	142	26	mouse	mouse	NN
cord-002180-gsdk5x3e	142	27	macrophage	macrophage	NN
cord-002180-gsdk5x3e	142	28	cell	cell	NN
cord-002180-gsdk5x3e	142	29	line	line	NN
cord-002180-gsdk5x3e	142	30	,	,	,
cord-002180-gsdk5x3e	142	31	in	in	IN
cord-002180-gsdk5x3e	142	32	the	the	DT
cord-002180-gsdk5x3e	142	33	absence	absence	NN
cord-002180-gsdk5x3e	142	34	of	of	IN
cord-002180-gsdk5x3e	142	35	other	other	JJ
cord-002180-gsdk5x3e	142	36	viral	viral	JJ
cord-002180-gsdk5x3e	142	37	factors	factor	NNS
cord-002180-gsdk5x3e	142	38	.	.	.
cord-002180-gsdk5x3e	143	1	Changes	change	NNS
cord-002180-gsdk5x3e	143	2	to	to	IN
cord-002180-gsdk5x3e	143	3	the	the	DT
cord-002180-gsdk5x3e	143	4	host	host	NN
cord-002180-gsdk5x3e	143	5	cell	cell	NN
cord-002180-gsdk5x3e	143	6	cycle	cycle	NN
cord-002180-gsdk5x3e	143	7	post	post	JJ
cord-002180-gsdk5x3e	143	8	NS5	ns5	JJ
cord-002180-gsdk5x3e	143	9	expression	expression	NN
cord-002180-gsdk5x3e	143	10	was	be	VBD
cord-002180-gsdk5x3e	143	11	nearly	nearly	RB
cord-002180-gsdk5x3e	143	12	identical	identical	JJ
cord-002180-gsdk5x3e	143	13	to	to	IN
cord-002180-gsdk5x3e	143	14	that	that	DT
cord-002180-gsdk5x3e	143	15	observed	observe	VBN
cord-002180-gsdk5x3e	143	16	under	under	IN
cord-002180-gsdk5x3e	143	17	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	143	18	infection	infection	NN
cord-002180-gsdk5x3e	143	19	with	with	IN
cord-002180-gsdk5x3e	143	20	the	the	DT
cord-002180-gsdk5x3e	143	21	G	g	NN
cord-002180-gsdk5x3e	143	22	0	0	CD
cord-002180-gsdk5x3e	143	23	/G	/g	SYM
cord-002180-gsdk5x3e	143	24	1	1	CD
cord-002180-gsdk5x3e	143	25	population	population	NN
cord-002180-gsdk5x3e	143	26	increasing	increase	VBG
cord-002180-gsdk5x3e	143	27	by	by	IN
cord-002180-gsdk5x3e	143	28	24	24	CD
cord-002180-gsdk5x3e	143	29	%	%	NN
cord-002180-gsdk5x3e	143	30	and	and	CC
cord-002180-gsdk5x3e	143	31	28	28	CD
cord-002180-gsdk5x3e	143	32	%	%	NN
cord-002180-gsdk5x3e	143	33	and	and	CC
cord-002180-gsdk5x3e	143	34	the	the	DT
cord-002180-gsdk5x3e	143	35	corresponding	correspond	VBG
cord-002180-gsdk5x3e	143	36	S	S	NNP
cord-002180-gsdk5x3e	143	37	phase	phase	NN
cord-002180-gsdk5x3e	143	38	population	population	NN
cord-002180-gsdk5x3e	143	39	decreasing	decrease	VBG
cord-002180-gsdk5x3e	143	40	by	by	IN
cord-002180-gsdk5x3e	143	41	26	26	CD
cord-002180-gsdk5x3e	143	42	%	%	NN
cord-002180-gsdk5x3e	143	43	and	and	CC
cord-002180-gsdk5x3e	143	44	27	27	CD
cord-002180-gsdk5x3e	143	45	%	%	NN
cord-002180-gsdk5x3e	143	46	respectively	respectively	RB
cord-002180-gsdk5x3e	143	47	.	.	.
cord-002180-gsdk5x3e	144	1	Expression	expression	NN
cord-002180-gsdk5x3e	144	2	of	of	IN
cord-002180-gsdk5x3e	144	3	NS5	NS5	NNP
cord-002180-gsdk5x3e	144	4	alone	alone	RB
cord-002180-gsdk5x3e	144	5	was	be	VBD
cord-002180-gsdk5x3e	144	6	sufficient	sufficient	JJ
cord-002180-gsdk5x3e	144	7	to	to	TO
cord-002180-gsdk5x3e	144	8	induce	induce	VB
cord-002180-gsdk5x3e	144	9	an	an	DT
cord-002180-gsdk5x3e	144	10	accumulation	accumulation	NN
cord-002180-gsdk5x3e	144	11	of	of	IN
cord-002180-gsdk5x3e	144	12	cells	cell	NNS
cord-002180-gsdk5x3e	144	13	in	in	IN
cord-002180-gsdk5x3e	144	14	the	the	DT
cord-002180-gsdk5x3e	144	15	G	g	NN
cord-002180-gsdk5x3e	144	16	0	0	CD
cord-002180-gsdk5x3e	144	17	/G	/g	SYM
cord-002180-gsdk5x3e	144	18	1	1	CD
cord-002180-gsdk5x3e	144	19	phase	phase	NN
cord-002180-gsdk5x3e	144	20	and	and	CC
cord-002180-gsdk5x3e	144	21	reduce	reduce	VB
cord-002180-gsdk5x3e	144	22	cyclin	cyclin	NN
cord-002180-gsdk5x3e	144	23	A	a	DT
cord-002180-gsdk5x3e	144	24	expression	expression	NN
cord-002180-gsdk5x3e	144	25	in	in	IN
cord-002180-gsdk5x3e	144	26	an	an	DT
cord-002180-gsdk5x3e	144	27	asynchronous	asynchronous	JJ
cord-002180-gsdk5x3e	144	28	population	population	NN
cord-002180-gsdk5x3e	144	29	.	.	.
cord-002180-gsdk5x3e	145	1	Further	further	JJ
cord-002180-gsdk5x3e	145	2	confirmation	confirmation	NN
cord-002180-gsdk5x3e	145	3	of	of	IN
cord-002180-gsdk5x3e	145	4	NS5	NS5	NNP
cord-002180-gsdk5x3e	145	5	as	as	IN
cord-002180-gsdk5x3e	145	6	the	the	DT
cord-002180-gsdk5x3e	145	7	cell	cell	NN
cord-002180-gsdk5x3e	145	8	cycle	cycle	NN
cord-002180-gsdk5x3e	145	9	regulator	regulator	NN
cord-002180-gsdk5x3e	145	10	comes	come	VBZ
cord-002180-gsdk5x3e	145	11	from	from	IN
cord-002180-gsdk5x3e	145	12	analyzing	analyze	VBG
cord-002180-gsdk5x3e	145	13	the	the	DT
cord-002180-gsdk5x3e	145	14	ability	ability	NN
cord-002180-gsdk5x3e	145	15	of	of	IN
cord-002180-gsdk5x3e	145	16	NS5	NS5	NNP
cord-002180-gsdk5x3e	145	17	to	to	TO
cord-002180-gsdk5x3e	145	18	inhibit	inhibit	VB
cord-002180-gsdk5x3e	145	19	the	the	DT
cord-002180-gsdk5x3e	145	20	G	g	NN
cord-002180-gsdk5x3e	145	21	1	1	CD
cord-002180-gsdk5x3e	145	22	/S	/S	NNP
cord-002180-gsdk5x3e	145	23	transition	transition	NN
cord-002180-gsdk5x3e	145	24	and	and	CC
cord-002180-gsdk5x3e	145	25	prevent	prevent	VB
cord-002180-gsdk5x3e	145	26	cyclin	cyclin	NN
cord-002180-gsdk5x3e	145	27	A	a	DT
cord-002180-gsdk5x3e	145	28	accumulating	accumulating	NN
cord-002180-gsdk5x3e	145	29	in	in	IN
cord-002180-gsdk5x3e	145	30	a	a	DT
cord-002180-gsdk5x3e	145	31	population	population	NN
cord-002180-gsdk5x3e	145	32	progressing	progress	VBG
cord-002180-gsdk5x3e	145	33	from	from	IN
cord-002180-gsdk5x3e	145	34	G	g	NN
cord-002180-gsdk5x3e	145	35	1	1	CD
cord-002180-gsdk5x3e	145	36	into	into	IN
cord-002180-gsdk5x3e	145	37	S	s	NN
cord-002180-gsdk5x3e	145	38	phase	phase	NN
cord-002180-gsdk5x3e	145	39	.	.	.
cord-002180-gsdk5x3e	146	1	These	these	DT
cord-002180-gsdk5x3e	146	2	effects	effect	NNS
cord-002180-gsdk5x3e	146	3	on	on	IN
cord-002180-gsdk5x3e	146	4	the	the	DT
cord-002180-gsdk5x3e	146	5	host	host	NN
cord-002180-gsdk5x3e	146	6	cell	cell	NN
cord-002180-gsdk5x3e	146	7	cycle	cycle	NN
cord-002180-gsdk5x3e	146	8	are	be	VBP
cord-002180-gsdk5x3e	146	9	consistent	consistent	JJ
cord-002180-gsdk5x3e	146	10	with	with	IN
cord-002180-gsdk5x3e	146	11	the	the	DT
cord-002180-gsdk5x3e	146	12	observed	observed	JJ
cord-002180-gsdk5x3e	146	13	effects	effect	NNS
cord-002180-gsdk5x3e	146	14	of	of	IN
cord-002180-gsdk5x3e	146	15	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	146	16	infection	infection	NN
cord-002180-gsdk5x3e	146	17	,	,	,
cord-002180-gsdk5x3e	146	18	showing	show	VBG
cord-002180-gsdk5x3e	146	19	NS5	ns5	JJ
cord-002180-gsdk5x3e	146	20	to	to	TO
cord-002180-gsdk5x3e	146	21	be	be	VB
cord-002180-gsdk5x3e	146	22	a	a	DT
cord-002180-gsdk5x3e	146	23	causative	causative	JJ
cord-002180-gsdk5x3e	146	24	agent	agent	NN
cord-002180-gsdk5x3e	146	25	of	of	IN
cord-002180-gsdk5x3e	146	26	this	this	DT
cord-002180-gsdk5x3e	146	27	cell	cell	NN
cord-002180-gsdk5x3e	146	28	cycle	cycle	NN
cord-002180-gsdk5x3e	146	29	arrest	arrest	NN
cord-002180-gsdk5x3e	146	30	.	.	.
cord-002180-gsdk5x3e	147	1	It	-PRON-	PRP
cord-002180-gsdk5x3e	147	2	was	be	VBD
cord-002180-gsdk5x3e	147	3	initially	initially	RB
cord-002180-gsdk5x3e	147	4	hypothesized	hypothesize	VBN
cord-002180-gsdk5x3e	147	5	that	that	IN
cord-002180-gsdk5x3e	147	6	the	the	DT
cord-002180-gsdk5x3e	147	7	cell	cell	NN
cord-002180-gsdk5x3e	147	8	cycle	cycle	NN
cord-002180-gsdk5x3e	147	9	arrest	arrest	NN
cord-002180-gsdk5x3e	147	10	induced	induce	VBN
cord-002180-gsdk5x3e	147	11	by	by	IN
cord-002180-gsdk5x3e	147	12	NS5	NS5	NNP
cord-002180-gsdk5x3e	147	13	was	be	VBD
cord-002180-gsdk5x3e	147	14	due	due	JJ
cord-002180-gsdk5x3e	147	15	to	to	IN
cord-002180-gsdk5x3e	147	16	its	-PRON-	PRP$
cord-002180-gsdk5x3e	147	17	known	know	VBN
cord-002180-gsdk5x3e	147	18	interaction	interaction	NN
cord-002180-gsdk5x3e	147	19	with	with	IN
cord-002180-gsdk5x3e	147	20	host	host	NN
cord-002180-gsdk5x3e	147	21	eIF4G.	eIF4G.	.
cord-002180-gsdk5x3e	148	1	The	the	DT
cord-002180-gsdk5x3e	148	2	NS5	ns5	JJ
cord-002180-gsdk5x3e	148	3	protein	protein	NN
cord-002180-gsdk5x3e	148	4	from	from	IN
cord-002180-gsdk5x3e	148	5	several	several	JJ
cord-002180-gsdk5x3e	148	6	caliciviruses	caliciviruse	NNS
cord-002180-gsdk5x3e	148	7	has	have	VBZ
cord-002180-gsdk5x3e	148	8	been	be	VBN
cord-002180-gsdk5x3e	148	9	documented	document	VBN
cord-002180-gsdk5x3e	148	10	to	to	TO
cord-002180-gsdk5x3e	148	11	aid	aid	VB
cord-002180-gsdk5x3e	148	12	in	in	IN
cord-002180-gsdk5x3e	148	13	viral	viral	JJ
cord-002180-gsdk5x3e	148	14	protein	protein	NN
cord-002180-gsdk5x3e	148	15	translation	translation	NN
cord-002180-gsdk5x3e	148	16	,	,	,
cord-002180-gsdk5x3e	148	17	through	through	IN
cord-002180-gsdk5x3e	148	18	binding	bind	VBG
cord-002180-gsdk5x3e	148	19	to	to	IN
cord-002180-gsdk5x3e	148	20	several	several	JJ
cord-002180-gsdk5x3e	148	21	host	host	NN
cord-002180-gsdk5x3e	148	22	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	148	23	initiation	initiation	NN
cord-002180-gsdk5x3e	148	24	factors	factor	NNS
cord-002180-gsdk5x3e	148	25	and	and	CC
cord-002180-gsdk5x3e	148	26	recruiting	recruiting	NN
cord-002180-gsdk5x3e	148	27	ribosomes	ribosome	NNS
cord-002180-gsdk5x3e	148	28	to	to	IN
cord-002180-gsdk5x3e	148	29	the	the	DT
cord-002180-gsdk5x3e	148	30	site	site	NN
cord-002180-gsdk5x3e	148	31	of	of	IN
cord-002180-gsdk5x3e	148	32	viral	viral	JJ
cord-002180-gsdk5x3e	148	33	replication	replication	NN
cord-002180-gsdk5x3e	148	34	[	[	-LRB-
cord-002180-gsdk5x3e	148	35	11	11	CD
cord-002180-gsdk5x3e	148	36	,	,	,
cord-002180-gsdk5x3e	148	37	30	30	CD
cord-002180-gsdk5x3e	148	38	,	,	,
cord-002180-gsdk5x3e	148	39	[	[	-LRB-
cord-002180-gsdk5x3e	148	40	38	38	CD
cord-002180-gsdk5x3e	148	41	]	]	-RRB-
cord-002180-gsdk5x3e	148	42	[	[	-LRB-
cord-002180-gsdk5x3e	148	43	39	39	CD
cord-002180-gsdk5x3e	148	44	]	]	-RRB-
cord-002180-gsdk5x3e	148	45	[	[	-LRB-
cord-002180-gsdk5x3e	148	46	40	40	CD
cord-002180-gsdk5x3e	148	47	]	]	-RRB-
cord-002180-gsdk5x3e	148	48	.	.	.
cord-002180-gsdk5x3e	149	1	The	the	DT
cord-002180-gsdk5x3e	149	2	concentration	concentration	NN
cord-002180-gsdk5x3e	149	3	of	of	IN
cord-002180-gsdk5x3e	149	4	host	host	NN
cord-002180-gsdk5x3e	149	5	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	149	6	initiation	initiation	NN
cord-002180-gsdk5x3e	149	7	factors	factor	NNS
cord-002180-gsdk5x3e	149	8	by	by	IN
cord-002180-gsdk5x3e	149	9	VPg	VPg	NNS
cord-002180-gsdk5x3e	149	10	proteins	protein	NNS
cord-002180-gsdk5x3e	149	11	is	be	VBZ
cord-002180-gsdk5x3e	149	12	predicted	predict	VBN
cord-002180-gsdk5x3e	149	13	to	to	TO
cord-002180-gsdk5x3e	149	14	impair	impair	VB
cord-002180-gsdk5x3e	149	15	host	host	NN
cord-002180-gsdk5x3e	149	16	translation	translation	NN
cord-002180-gsdk5x3e	149	17	[	[	-LRB-
cord-002180-gsdk5x3e	149	18	36	36	CD
cord-002180-gsdk5x3e	149	19	]	]	-RRB-
cord-002180-gsdk5x3e	149	20	.	.	.
cord-002180-gsdk5x3e	150	1	Shut	shut	VB
cord-002180-gsdk5x3e	150	2	-	-	HYPH
cord-002180-gsdk5x3e	150	3	off	off	NN
cord-002180-gsdk5x3e	150	4	of	of	IN
cord-002180-gsdk5x3e	150	5	host	host	NN
cord-002180-gsdk5x3e	150	6	protein	protein	NN
cord-002180-gsdk5x3e	150	7	translation	translation	NN
cord-002180-gsdk5x3e	150	8	has	have	VBZ
cord-002180-gsdk5x3e	150	9	been	be	VBN
cord-002180-gsdk5x3e	150	10	shown	show	VBN
cord-002180-gsdk5x3e	150	11	to	to	TO
cord-002180-gsdk5x3e	150	12	induce	induce	VB
cord-002180-gsdk5x3e	150	13	cell	cell	NN
cord-002180-gsdk5x3e	150	14	cycle	cycle	NN
cord-002180-gsdk5x3e	150	15	arrests	arrest	NNS
cord-002180-gsdk5x3e	150	16	in	in	IN
cord-002180-gsdk5x3e	150	17	several	several	JJ
cord-002180-gsdk5x3e	150	18	cell	cell	NN
cord-002180-gsdk5x3e	150	19	phases	phase	NNS
cord-002180-gsdk5x3e	150	20	including	include	VBG
cord-002180-gsdk5x3e	150	21	G	g	NN
cord-002180-gsdk5x3e	150	22	1	1	CD
cord-002180-gsdk5x3e	150	23	and	and	CC
cord-002180-gsdk5x3e	150	24	G	g	NN
cord-002180-gsdk5x3e	150	25	2	2	CD
cord-002180-gsdk5x3e	150	26	/M	/M	.
cord-002180-gsdk5x3e	150	27	[	[	-LRB-
cord-002180-gsdk5x3e	150	28	41	41	CD
cord-002180-gsdk5x3e	150	29	,	,	,
cord-002180-gsdk5x3e	150	30	42	42	CD
cord-002180-gsdk5x3e	150	31	]	]	-RRB-
cord-002180-gsdk5x3e	150	32	.	.	.
cord-002180-gsdk5x3e	151	1	We	-PRON-	PRP
cord-002180-gsdk5x3e	151	2	analyzed	analyze	VBD
cord-002180-gsdk5x3e	151	3	the	the	DT
cord-002180-gsdk5x3e	151	4	impact	impact	NN
cord-002180-gsdk5x3e	151	5	on	on	IN
cord-002180-gsdk5x3e	151	6	the	the	DT
cord-002180-gsdk5x3e	151	7	host	host	NN
cord-002180-gsdk5x3e	151	8	cell	cell	NN
cord-002180-gsdk5x3e	151	9	cycle	cycle	NN
cord-002180-gsdk5x3e	151	10	of	of	IN
cord-002180-gsdk5x3e	151	11	NS5	ns5	JJ
cord-002180-gsdk5x3e	151	12	binding	binding	NN
cord-002180-gsdk5x3e	151	13	to	to	TO
cord-002180-gsdk5x3e	151	14	host	host	VB
cord-002180-gsdk5x3e	151	15	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	151	16	initiation	initiation	NN
cord-002180-gsdk5x3e	151	17	factors	factor	NNS
cord-002180-gsdk5x3e	151	18	through	through	IN
cord-002180-gsdk5x3e	151	19	the	the	DT
cord-002180-gsdk5x3e	151	20	introduction	introduction	NN
cord-002180-gsdk5x3e	151	21	of	of	IN
cord-002180-gsdk5x3e	151	22	an	an	DT
cord-002180-gsdk5x3e	151	23	amino	amino	NN
cord-002180-gsdk5x3e	151	24	acid	acid	NN
cord-002180-gsdk5x3e	151	25	substitution	substitution	NN
cord-002180-gsdk5x3e	151	26	that	that	WDT
cord-002180-gsdk5x3e	151	27	was	be	VBD
cord-002180-gsdk5x3e	151	28	known	know	VBN
cord-002180-gsdk5x3e	151	29	to	to	TO
cord-002180-gsdk5x3e	151	30	impede	impede	VB
cord-002180-gsdk5x3e	151	31	binding	bind	VBG
cord-002180-gsdk5x3e	151	32	to	to	IN
cord-002180-gsdk5x3e	151	33	eIF4	eIF4	NNP
cord-002180-gsdk5x3e	151	34	G	G	NNP
cord-002180-gsdk5x3e	151	35	[	[	-LRB-
cord-002180-gsdk5x3e	151	36	30	30	CD
cord-002180-gsdk5x3e	151	37	]	]	-RRB-
cord-002180-gsdk5x3e	151	38	.	.	.
cord-002180-gsdk5x3e	152	1	The	the	DT
cord-002180-gsdk5x3e	152	2	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	152	3	)	)	-RRB-
cord-002180-gsdk5x3e	152	4	substitution	substitution	NN
cord-002180-gsdk5x3e	152	5	had	have	VBD
cord-002180-gsdk5x3e	152	6	no	no	DT
cord-002180-gsdk5x3e	152	7	effect	effect	NN
cord-002180-gsdk5x3e	152	8	on	on	IN
cord-002180-gsdk5x3e	152	9	the	the	DT
cord-002180-gsdk5x3e	152	10	ability	ability	NN
cord-002180-gsdk5x3e	152	11	of	of	IN
cord-002180-gsdk5x3e	152	12	NS5	NS5	NNP
cord-002180-gsdk5x3e	152	13	to	to	TO
cord-002180-gsdk5x3e	152	14	induce	induce	VB
cord-002180-gsdk5x3e	152	15	a	a	DT
cord-002180-gsdk5x3e	152	16	G	g	NN
cord-002180-gsdk5x3e	152	17	1	1	CD
cord-002180-gsdk5x3e	152	18	arrest	arrest	NN
cord-002180-gsdk5x3e	152	19	indicating	indicate	VBG
cord-002180-gsdk5x3e	152	20	an	an	DT
cord-002180-gsdk5x3e	152	21	alternative	alternative	JJ
cord-002180-gsdk5x3e	152	22	mechanism	mechanism	NN
cord-002180-gsdk5x3e	152	23	is	be	VBZ
cord-002180-gsdk5x3e	152	24	responsible	responsible	JJ
cord-002180-gsdk5x3e	152	25	for	for	IN
cord-002180-gsdk5x3e	152	26	the	the	DT
cord-002180-gsdk5x3e	152	27	cell	cell	NN
cord-002180-gsdk5x3e	152	28	cycle	cycle	NN
cord-002180-gsdk5x3e	152	29	manipulation	manipulation	NN
cord-002180-gsdk5x3e	152	30	.	.	.
cord-002180-gsdk5x3e	153	1	Another	another	DT
cord-002180-gsdk5x3e	153	2	well	well	RB
cord-002180-gsdk5x3e	153	3	characterized	characterize	VBN
cord-002180-gsdk5x3e	153	4	function	function	NN
cord-002180-gsdk5x3e	153	5	of	of	IN
cord-002180-gsdk5x3e	153	6	NS5	NS5	NNP
cord-002180-gsdk5x3e	153	7	is	be	VBZ
cord-002180-gsdk5x3e	153	8	in	in	IN
cord-002180-gsdk5x3e	153	9	priming	priming	NN
cord-002180-gsdk5x3e	153	10	of	of	IN
cord-002180-gsdk5x3e	153	11	RNA	RNA	NNP
cord-002180-gsdk5x3e	153	12	synthesis	synthesis	NN
cord-002180-gsdk5x3e	153	13	via	via	IN
cord-002180-gsdk5x3e	153	14	attachment	attachment	NN
cord-002180-gsdk5x3e	153	15	to	to	IN
cord-002180-gsdk5x3e	153	16	viral	viral	JJ
cord-002180-gsdk5x3e	153	17	genomic	genomic	JJ
cord-002180-gsdk5x3e	153	18	and	and	CC
cord-002180-gsdk5x3e	153	19	subgenomic	subgenomic	NNP
cord-002180-gsdk5x3e	153	20	RNA	RNA	NNP
cord-002180-gsdk5x3e	153	21	.	.	.
cord-002180-gsdk5x3e	154	1	While	while	IN
cord-002180-gsdk5x3e	154	2	nucleotidylation	nucleotidylation	NN
cord-002180-gsdk5x3e	154	3	of	of	IN
cord-002180-gsdk5x3e	154	4	the	the	DT
cord-002180-gsdk5x3e	154	5	NS5	ns5	JJ
cord-002180-gsdk5x3e	154	6	Y26	Y26	NNP
cord-002180-gsdk5x3e	154	7	residue	residue	NN
cord-002180-gsdk5x3e	154	8	is	be	VBZ
cord-002180-gsdk5x3e	154	9	Dunnett	Dunnett	NNP
cord-002180-gsdk5x3e	154	10	's	's	POS
cord-002180-gsdk5x3e	154	11	post	post	JJ
cord-002180-gsdk5x3e	154	12	-	-	JJ
cord-002180-gsdk5x3e	154	13	test	test	NN
cord-002180-gsdk5x3e	154	14	.	.	.
cord-002180-gsdk5x3e	155	1	*	*	NFP
cord-002180-gsdk5x3e	155	2	,	,	,
cord-002180-gsdk5x3e	155	3	P	p	NN
cord-002180-gsdk5x3e	155	4	0.05	0.05	CD
cord-002180-gsdk5x3e	155	5	;	;	.
cord-002180-gsdk5x3e	156	1	*	*	NFP
cord-002180-gsdk5x3e	157	1	*	*	NFP
cord-002180-gsdk5x3e	157	2	,	,	,
cord-002180-gsdk5x3e	157	3	P	p	NN
cord-002180-gsdk5x3e	157	4	0.01	0.01	CD
cord-002180-gsdk5x3e	157	5	;	;	:
cord-002180-gsdk5x3e	158	1	*	*	NFP
cord-002180-gsdk5x3e	158	2	*	*	NFP
cord-002180-gsdk5x3e	158	3	*	*	NFP
cord-002180-gsdk5x3e	158	4	,	,	,
cord-002180-gsdk5x3e	158	5	P	p	NN
cord-002180-gsdk5x3e	158	6	0.001	0.001	CD
cord-002180-gsdk5x3e	158	7	.	.	.
cord-002180-gsdk5x3e	159	1	(	(	-LRB-
cord-002180-gsdk5x3e	159	2	C	C	NNP
cord-002180-gsdk5x3e	159	3	)	)	-RRB-
cord-002180-gsdk5x3e	159	4	Expression	expression	NN
cord-002180-gsdk5x3e	159	5	of	of	IN
cord-002180-gsdk5x3e	159	6	NS1	ns1	NN
cord-002180-gsdk5x3e	159	7	-	-	HYPH
cord-002180-gsdk5x3e	159	8	2	2	CD
cord-002180-gsdk5x3e	159	9	,	,	,
cord-002180-gsdk5x3e	159	10	WT	WT	NNP
cord-002180-gsdk5x3e	159	11	NS5	NS5	NNP
cord-002180-gsdk5x3e	159	12	,	,	,
cord-002180-gsdk5x3e	159	13	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	159	14	)	)	-RRB-
cord-002180-gsdk5x3e	159	15	and	and	CC
cord-002180-gsdk5x3e	159	16	Cyclin	Cyclin	NNP
cord-002180-gsdk5x3e	159	17	A	A	NNP
cord-002180-gsdk5x3e	159	18	was	be	VBD
cord-002180-gsdk5x3e	159	19	determined	determine	VBN
cord-002180-gsdk5x3e	159	20	by	by	IN
cord-002180-gsdk5x3e	159	21	Western	western	JJ
cord-002180-gsdk5x3e	159	22	blot	blot	NN
cord-002180-gsdk5x3e	159	23	analysis	analysis	NN
cord-002180-gsdk5x3e	159	24	,	,	,
cord-002180-gsdk5x3e	159	25	actin	actin	NN
cord-002180-gsdk5x3e	159	26	was	be	VBD
cord-002180-gsdk5x3e	159	27	used	use	VBN
cord-002180-gsdk5x3e	159	28	as	as	IN
cord-002180-gsdk5x3e	159	29	a	a	DT
cord-002180-gsdk5x3e	159	30	loading	loading	NN
cord-002180-gsdk5x3e	159	31	control	control	NN
cord-002180-gsdk5x3e	159	32	.	.	.
cord-002180-gsdk5x3e	160	1	(	(	-LRB-
cord-002180-gsdk5x3e	160	2	D	d	NN
cord-002180-gsdk5x3e	160	3	)	)	-RRB-
cord-002180-gsdk5x3e	161	1	Cyclin	Cyclin	NNP
cord-002180-gsdk5x3e	161	2	A	a	DT
cord-002180-gsdk5x3e	161	3	levels	level	NNS
cord-002180-gsdk5x3e	161	4	from	from	IN
cord-002180-gsdk5x3e	161	5	three	three	CD
cord-002180-gsdk5x3e	161	6	experiments	experiment	NNS
cord-002180-gsdk5x3e	161	7	were	be	VBD
cord-002180-gsdk5x3e	161	8	quantified	quantify	VBN
cord-002180-gsdk5x3e	161	9	with	with	IN
cord-002180-gsdk5x3e	161	10	Image	Image	NNP
cord-002180-gsdk5x3e	161	11	Studio	Studio	NNP
cord-002180-gsdk5x3e	161	12	Lite	Lite	NNP
cord-002180-gsdk5x3e	161	13	(	(	-LRB-
cord-002180-gsdk5x3e	161	14	LI	LI	NNP
cord-002180-gsdk5x3e	161	15	-	-	HYPH
cord-002180-gsdk5x3e	161	16	COR	COR	NNP
cord-002180-gsdk5x3e	161	17	)	)	-RRB-
cord-002180-gsdk5x3e	161	18	and	and	CC
cord-002180-gsdk5x3e	161	19	normalised	normalise	VBD
cord-002180-gsdk5x3e	161	20	against	against	IN
cord-002180-gsdk5x3e	161	21	the	the	DT
cord-002180-gsdk5x3e	161	22	results	result	NNS
cord-002180-gsdk5x3e	161	23	for	for	IN
cord-002180-gsdk5x3e	161	24	actin	actin	NN
cord-002180-gsdk5x3e	161	25	and	and	CC
cord-002180-gsdk5x3e	161	26	results	result	NNS
cord-002180-gsdk5x3e	161	27	presented	present	VBN
cord-002180-gsdk5x3e	161	28	as	as	IN
cord-002180-gsdk5x3e	161	29	means	mean	NNS
cord-002180-gsdk5x3e	161	30	and	and	CC
cord-002180-gsdk5x3e	161	31	SD	sd	NN
cord-002180-gsdk5x3e	161	32	from	from	IN
cord-002180-gsdk5x3e	161	33	three	three	CD
cord-002180-gsdk5x3e	161	34	independent	independent	JJ
cord-002180-gsdk5x3e	161	35	experiments	experiment	NNS
cord-002180-gsdk5x3e	161	36	.	.	.
cord-002180-gsdk5x3e	162	1	Statistical	statistical	JJ
cord-002180-gsdk5x3e	162	2	significance	significance	NN
cord-002180-gsdk5x3e	162	3	was	be	VBD
cord-002180-gsdk5x3e	162	4	determined	determine	VBN
cord-002180-gsdk5x3e	162	5	for	for	IN
cord-002180-gsdk5x3e	162	6	comparisons	comparison	NNS
cord-002180-gsdk5x3e	162	7	between	between	IN
cord-002180-gsdk5x3e	162	8	transfected	transfected	JJ
cord-002180-gsdk5x3e	162	9	populations	population	NNS
cord-002180-gsdk5x3e	162	10	and	and	CC
cord-002180-gsdk5x3e	162	11	the	the	DT
cord-002180-gsdk5x3e	162	12	mock	mock	NN
cord-002180-gsdk5x3e	162	13	-	-	HYPH
cord-002180-gsdk5x3e	162	14	transfected	transfecte	VBN
cord-002180-gsdk5x3e	162	15	population	population	NN
cord-002180-gsdk5x3e	162	16	using	use	VBG
cord-002180-gsdk5x3e	162	17	a	a	DT
cord-002180-gsdk5x3e	162	18	one	one	CD
cord-002180-gsdk5x3e	162	19	-	-	HYPH
cord-002180-gsdk5x3e	162	20	sample	sample	NN
cord-002180-gsdk5x3e	162	21	t	t	NN
cord-002180-gsdk5x3e	162	22	-	-	HYPH
cord-002180-gsdk5x3e	162	23	test	test	NN
cord-002180-gsdk5x3e	162	24	.	.	.
cord-002180-gsdk5x3e	163	1	*	*	NFP
cord-002180-gsdk5x3e	163	2	,	,	,
cord-002180-gsdk5x3e	163	3	P	p	NN
cord-002180-gsdk5x3e	163	4	0.05	0.05	CD
cord-002180-gsdk5x3e	163	5	;	;	.
cord-002180-gsdk5x3e	164	1	*	*	NFP
cord-002180-gsdk5x3e	164	2	*	*	NFP
cord-002180-gsdk5x3e	164	3	,	,	,
cord-002180-gsdk5x3e	164	4	P	p	NN
cord-002180-gsdk5x3e	164	5	0.01	0.01	CD
cord-002180-gsdk5x3e	164	6	.	.	.
cord-002180-gsdk5x3e	165	1	unlikely	unlikely	JJ
cord-002180-gsdk5x3e	165	2	in	in	IN
cord-002180-gsdk5x3e	165	3	the	the	DT
cord-002180-gsdk5x3e	165	4	absence	absence	NN
cord-002180-gsdk5x3e	165	5	of	of	IN
cord-002180-gsdk5x3e	165	6	viral	viral	JJ
cord-002180-gsdk5x3e	165	7	RNA	rna	NN
cord-002180-gsdk5x3e	165	8	polymerase	polymerase	NN
cord-002180-gsdk5x3e	165	9	(	(	-LRB-
cord-002180-gsdk5x3e	165	10	NS7	NS7	NNP
cord-002180-gsdk5x3e	165	11	)	)	-RRB-
cord-002180-gsdk5x3e	165	12	we	-PRON-	PRP
cord-002180-gsdk5x3e	165	13	wanted	want	VBD
cord-002180-gsdk5x3e	165	14	to	to	TO
cord-002180-gsdk5x3e	165	15	confirm	confirm	VB
cord-002180-gsdk5x3e	165	16	that	that	IN
cord-002180-gsdk5x3e	165	17	Y26	Y26	NNP
cord-002180-gsdk5x3e	165	18	had	have	VBD
cord-002180-gsdk5x3e	165	19	no	no	DT
cord-002180-gsdk5x3e	165	20	role	role	NN
cord-002180-gsdk5x3e	165	21	in	in	IN
cord-002180-gsdk5x3e	165	22	cell	cell	NN
cord-002180-gsdk5x3e	165	23	cycle	cycle	NN
cord-002180-gsdk5x3e	165	24	arrest	arrest	NN
cord-002180-gsdk5x3e	165	25	.	.	.
cord-002180-gsdk5x3e	166	1	Attachment	Attachment	NNP
cord-002180-gsdk5x3e	166	2	to	to	TO
cord-002180-gsdk5x3e	166	3	host	host	VB
cord-002180-gsdk5x3e	166	4	RNA	RNA	NNP
cord-002180-gsdk5x3e	166	5	could	could	MD
cord-002180-gsdk5x3e	166	6	result	result	VB
cord-002180-gsdk5x3e	166	7	in	in	IN
cord-002180-gsdk5x3e	166	8	changes	change	NNS
cord-002180-gsdk5x3e	166	9	in	in	IN
cord-002180-gsdk5x3e	166	10	protein	protein	NN
cord-002180-gsdk5x3e	166	11	expression	expression	NN
cord-002180-gsdk5x3e	166	12	,	,	,
cord-002180-gsdk5x3e	166	13	leading	lead	VBG
cord-002180-gsdk5x3e	166	14	to	to	IN
cord-002180-gsdk5x3e	166	15	a	a	DT
cord-002180-gsdk5x3e	166	16	cell	cell	NN
cord-002180-gsdk5x3e	166	17	cycle	cycle	NN
cord-002180-gsdk5x3e	166	18	arrest	arrest	NN
cord-002180-gsdk5x3e	166	19	.	.	.
cord-002180-gsdk5x3e	167	1	The	the	DT
cord-002180-gsdk5x3e	167	2	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	167	3	)	)	-RRB-
cord-002180-gsdk5x3e	167	4	protein	protein	NN
cord-002180-gsdk5x3e	167	5	is	be	VBZ
cord-002180-gsdk5x3e	167	6	unable	unable	JJ
cord-002180-gsdk5x3e	167	7	to	to	TO
cord-002180-gsdk5x3e	167	8	undergo	undergo	VB
cord-002180-gsdk5x3e	167	9	the	the	DT
cord-002180-gsdk5x3e	167	10	nucleotidylation	nucleotidylation	NN
cord-002180-gsdk5x3e	167	11	reaction	reaction	NN
cord-002180-gsdk5x3e	167	12	that	that	WDT
cord-002180-gsdk5x3e	167	13	attaches	attach	VBZ
cord-002180-gsdk5x3e	167	14	NS5	ns5	JJ
cord-002180-gsdk5x3e	167	15	to	to	IN
cord-002180-gsdk5x3e	167	16	viral	viral	JJ
cord-002180-gsdk5x3e	167	17	RNA	RNA	NNP
cord-002180-gsdk5x3e	167	18	but	but	CC
cord-002180-gsdk5x3e	167	19	still	still	RB
cord-002180-gsdk5x3e	167	20	induced	induce	VBN
cord-002180-gsdk5x3e	167	21	cell	cell	NN
cord-002180-gsdk5x3e	167	22	cycle	cycle	NN
cord-002180-gsdk5x3e	167	23	changes	change	NNS
cord-002180-gsdk5x3e	167	24	in	in	IN
cord-002180-gsdk5x3e	167	25	an	an	DT
cord-002180-gsdk5x3e	167	26	analogous	analogous	JJ
cord-002180-gsdk5x3e	167	27	manner	manner	NN
cord-002180-gsdk5x3e	167	28	to	to	IN
cord-002180-gsdk5x3e	167	29	WT	WT	NNP
cord-002180-gsdk5x3e	167	30	NS5	NS5	NNP
cord-002180-gsdk5x3e	167	31	.	.	.
cord-002180-gsdk5x3e	168	1	This	this	DT
cord-002180-gsdk5x3e	168	2	indicates	indicate	VBZ
cord-002180-gsdk5x3e	168	3	that	that	DT
cord-002180-gsdk5x3e	168	4	attachment	attachment	NN
cord-002180-gsdk5x3e	168	5	to	to	IN
cord-002180-gsdk5x3e	168	6	RNA	RNA	NNP
cord-002180-gsdk5x3e	168	7	via	via	IN
cord-002180-gsdk5x3e	168	8	the	the	DT
cord-002180-gsdk5x3e	168	9	Y26	Y26	NNP
cord-002180-gsdk5x3e	168	10	residue	residue	NN
cord-002180-gsdk5x3e	168	11	is	be	VBZ
cord-002180-gsdk5x3e	168	12	not	not	RB
cord-002180-gsdk5x3e	168	13	the	the	DT
cord-002180-gsdk5x3e	168	14	cause	cause	NN
cord-002180-gsdk5x3e	168	15	of	of	IN
cord-002180-gsdk5x3e	168	16	cell	cell	NN
cord-002180-gsdk5x3e	168	17	cycle	cycle	NN
cord-002180-gsdk5x3e	168	18	affects	affect	VBZ
cord-002180-gsdk5x3e	168	19	.	.	.
cord-002180-gsdk5x3e	169	1	MNV	MNV	NNP
cord-002180-gsdk5x3e	169	2	NS5	NS5	NNP
cord-002180-gsdk5x3e	169	3	is	be	VBZ
cord-002180-gsdk5x3e	169	4	indicated	indicate	VBN
cord-002180-gsdk5x3e	169	5	to	to	TO
cord-002180-gsdk5x3e	169	6	be	be	VB
cord-002180-gsdk5x3e	169	7	located	locate	VBN
cord-002180-gsdk5x3e	169	8	in	in	IN
cord-002180-gsdk5x3e	169	9	the	the	DT
cord-002180-gsdk5x3e	169	10	perinuclear	perinuclear	NNP
cord-002180-gsdk5x3e	169	11	region	region	NN
cord-002180-gsdk5x3e	169	12	,	,	,
cord-002180-gsdk5x3e	169	13	so	so	IN
cord-002180-gsdk5x3e	169	14	an	an	DT
cord-002180-gsdk5x3e	169	15	interaction	interaction	NN
cord-002180-gsdk5x3e	169	16	with	with	IN
cord-002180-gsdk5x3e	169	17	host	host	NN
cord-002180-gsdk5x3e	169	18	DNA	DNA	NNP
cord-002180-gsdk5x3e	169	19	is	be	VBZ
cord-002180-gsdk5x3e	169	20	unlikely	unlikely	JJ
cord-002180-gsdk5x3e	169	21	[	[	-LRB-
cord-002180-gsdk5x3e	169	22	43	43	CD
cord-002180-gsdk5x3e	169	23	]	]	-RRB-
cord-002180-gsdk5x3e	169	24	.	.	.
cord-002180-gsdk5x3e	170	1	Because	because	IN
cord-002180-gsdk5x3e	170	2	the	the	DT
cord-002180-gsdk5x3e	170	3	NS5(Y26A	NS5(Y26A	NNP
cord-002180-gsdk5x3e	170	4	)	)	-RRB-
cord-002180-gsdk5x3e	170	5	and	and	CC
cord-002180-gsdk5x3e	170	6	NS5(F123A	NS5(F123A	NNP
cord-002180-gsdk5x3e	170	7	)	)	-RRB-
cord-002180-gsdk5x3e	170	8	substitutions	substitution	NNS
cord-002180-gsdk5x3e	170	9	could	could	MD
cord-002180-gsdk5x3e	170	10	still	still	RB
cord-002180-gsdk5x3e	170	11	induce	induce	VB
cord-002180-gsdk5x3e	170	12	cell	cell	NN
cord-002180-gsdk5x3e	170	13	cycle	cycle	NN
cord-002180-gsdk5x3e	170	14	control	control	NN
cord-002180-gsdk5x3e	170	15	suggests	suggest	VBZ
cord-002180-gsdk5x3e	170	16	that	that	IN
cord-002180-gsdk5x3e	170	17	the	the	DT
cord-002180-gsdk5x3e	170	18	NS5	ns5	JJ
cord-002180-gsdk5x3e	170	19	induced	induce	VBN
cord-002180-gsdk5x3e	170	20	G	G	NNP
cord-002180-gsdk5x3e	170	21	1	1	CD
cord-002180-gsdk5x3e	170	22	/S	/S	NNP
cord-002180-gsdk5x3e	170	23	arrest	arrest	NN
cord-002180-gsdk5x3e	170	24	occurs	occur	VBZ
cord-002180-gsdk5x3e	170	25	through	through	IN
cord-002180-gsdk5x3e	170	26	an	an	DT
cord-002180-gsdk5x3e	170	27	as	as	RB
cord-002180-gsdk5x3e	170	28	yet	yet	RB
cord-002180-gsdk5x3e	170	29	uncharacterized	uncharacterized	JJ
cord-002180-gsdk5x3e	170	30	activity	activity	NN
cord-002180-gsdk5x3e	170	31	.	.	.
cord-002180-gsdk5x3e	171	1	In	in	IN
cord-002180-gsdk5x3e	171	2	this	this	DT
cord-002180-gsdk5x3e	171	3	study	study	NN
cord-002180-gsdk5x3e	171	4	,	,	,
cord-002180-gsdk5x3e	171	5	our	-PRON-	PRP$
cord-002180-gsdk5x3e	171	6	data	data	NN
cord-002180-gsdk5x3e	171	7	discovers	discover	VBZ
cord-002180-gsdk5x3e	171	8	a	a	DT
cord-002180-gsdk5x3e	171	9	viral	viral	JJ
cord-002180-gsdk5x3e	171	10	protein	protein	NN
cord-002180-gsdk5x3e	171	11	that	that	IN
cord-002180-gsdk5x3e	171	12	independent	independent	JJ
cord-002180-gsdk5x3e	171	13	of	of	IN
cord-002180-gsdk5x3e	171	14	other	other	JJ
cord-002180-gsdk5x3e	171	15	viral	viral	JJ
cord-002180-gsdk5x3e	171	16	proteins	protein	NNS
cord-002180-gsdk5x3e	171	17	is	be	VBZ
cord-002180-gsdk5x3e	171	18	able	able	JJ
cord-002180-gsdk5x3e	171	19	to	to	TO
cord-002180-gsdk5x3e	171	20	induce	induce	VB
cord-002180-gsdk5x3e	171	21	cell	cell	NN
cord-002180-gsdk5x3e	171	22	cycle	cycle	NN
cord-002180-gsdk5x3e	171	23	manipulation	manipulation	NN
cord-002180-gsdk5x3e	171	24	and	and	CC
cord-002180-gsdk5x3e	171	25	identifies	identify	VBZ
cord-002180-gsdk5x3e	171	26	a	a	DT
cord-002180-gsdk5x3e	171	27	new	new	JJ
cord-002180-gsdk5x3e	171	28	function	function	NN
cord-002180-gsdk5x3e	171	29	of	of	IN
cord-002180-gsdk5x3e	171	30	the	the	DT
cord-002180-gsdk5x3e	171	31	multi	multi	JJ
cord-002180-gsdk5x3e	171	32	-	-	JJ
cord-002180-gsdk5x3e	171	33	faceted	faceted	JJ
cord-002180-gsdk5x3e	171	34	NS5	ns5	JJ
cord-002180-gsdk5x3e	171	35	protein	protein	NN
cord-002180-gsdk5x3e	171	36	.	.	.
cord-002180-gsdk5x3e	172	1	The	the	DT
cord-002180-gsdk5x3e	172	2	detailed	detailed	JJ
cord-002180-gsdk5x3e	172	3	mechanism	mechanism	NN
cord-002180-gsdk5x3e	172	4	of	of	IN
cord-002180-gsdk5x3e	172	5	how	how	WRB
cord-002180-gsdk5x3e	172	6	NS5	ns5	JJ
cord-002180-gsdk5x3e	172	7	is	be	VBZ
cord-002180-gsdk5x3e	172	8	inhibiting	inhibit	VBG
cord-002180-gsdk5x3e	172	9	cell	cell	NN
cord-002180-gsdk5x3e	172	10	cycle	cycle	NN
cord-002180-gsdk5x3e	172	11	progression	progression	NN
cord-002180-gsdk5x3e	172	12	may	may	MD
cord-002180-gsdk5x3e	172	13	lie	lie	VB
cord-002180-gsdk5x3e	172	14	with	with	IN
cord-002180-gsdk5x3e	172	15	the	the	DT
cord-002180-gsdk5x3e	172	16	observed	observed	JJ
cord-002180-gsdk5x3e	172	17	decrease	decrease	NN
cord-002180-gsdk5x3e	172	18	in	in	IN
cord-002180-gsdk5x3e	172	19	cyclin	cyclin	NN
cord-002180-gsdk5x3e	172	20	A	a	DT
cord-002180-gsdk5x3e	172	21	expression	expression	NN
cord-002180-gsdk5x3e	172	22	with	with	IN
cord-002180-gsdk5x3e	172	23	further	further	JJ
cord-002180-gsdk5x3e	172	24	studies	study	NNS
cord-002180-gsdk5x3e	172	25	needed	need	VBN
cord-002180-gsdk5x3e	172	26	to	to	TO
cord-002180-gsdk5x3e	172	27	examine	examine	VB
cord-002180-gsdk5x3e	172	28	this	this	DT
cord-002180-gsdk5x3e	172	29	interaction	interaction	NN
cord-002180-gsdk5x3e	172	30	.	.	.
cord-002180-gsdk5x3e	173	1	Nevertheless	nevertheless	RB
cord-002180-gsdk5x3e	173	2	,	,	,
cord-002180-gsdk5x3e	173	3	these	these	DT
cord-002180-gsdk5x3e	173	4	results	result	NNS
cord-002180-gsdk5x3e	173	5	reinforce	reinforce	VBP
cord-002180-gsdk5x3e	173	6	the	the	DT
cord-002180-gsdk5x3e	173	7	importance	importance	NN
cord-002180-gsdk5x3e	173	8	of	of	IN
cord-002180-gsdk5x3e	173	9	the	the	DT
cord-002180-gsdk5x3e	173	10	multifunctional	multifunctional	JJ
cord-002180-gsdk5x3e	173	11	NS5	ns5	NN
cord-002180-gsdk5x3e	173	12	in	in	IN
cord-002180-gsdk5x3e	173	13	norovirus	norovirus	NN
cord-002180-gsdk5x3e	173	14	replication	replication	NN
cord-002180-gsdk5x3e	173	15	.	.	.
cord-002180-gsdk5x3e	174	1	Norwalk	Norwalk	NNP
cord-002180-gsdk5x3e	174	2	virus	virus	NN
cord-002180-gsdk5x3e	174	3	genome	genome	NN
cord-002180-gsdk5x3e	174	4	cloning	cloning	NN
cord-002180-gsdk5x3e	174	5	and	and	CC
cord-002180-gsdk5x3e	174	6	characterization	characterization	NN
cord-002180-gsdk5x3e	174	7	Human	human	JJ
cord-002180-gsdk5x3e	174	8	sapoviruses	sapoviruse	NNS
cord-002180-gsdk5x3e	174	9	:	:	:
cord-002180-gsdk5x3e	174	10	genetic	genetic	JJ
cord-002180-gsdk5x3e	174	11	diversity	diversity	NN
cord-002180-gsdk5x3e	174	12	,	,	,
cord-002180-gsdk5x3e	174	13	recombination	recombination	NN
cord-002180-gsdk5x3e	174	14	,	,	,
cord-002180-gsdk5x3e	174	15	and	and	CC
cord-002180-gsdk5x3e	174	16	classification	classification	NN
cord-002180-gsdk5x3e	174	17	Novel	Novel	NNP
cord-002180-gsdk5x3e	174	18	calicivirus	calicivirus	NNP
cord-002180-gsdk5x3e	174	19	identified	identify	VBN
cord-002180-gsdk5x3e	174	20	in	in	IN
cord-002180-gsdk5x3e	174	21	rabbits	rabbit	NNS
cord-002180-gsdk5x3e	174	22	Feline	feline	JJ
cord-002180-gsdk5x3e	174	23	calicivirus	calicivirus	JJ
cord-002180-gsdk5x3e	174	24	infection	infection	NN
cord-002180-gsdk5x3e	174	25	.	.	.
cord-002180-gsdk5x3e	175	1	ABCD	ABCD	NNP
cord-002180-gsdk5x3e	175	2	guidelines	guideline	NNS
cord-002180-gsdk5x3e	175	3	on	on	IN
cord-002180-gsdk5x3e	175	4	prevention	prevention	NN
cord-002180-gsdk5x3e	175	5	and	and	CC
cord-002180-gsdk5x3e	175	6	management	management	NN
cord-002180-gsdk5x3e	175	7	STAT1-dependent	STAT1-dependent	NNP
cord-002180-gsdk5x3e	175	8	innate	innate	JJ
cord-002180-gsdk5x3e	175	9	immunity	immunity	NN
cord-002180-gsdk5x3e	175	10	to	to	IN
cord-002180-gsdk5x3e	175	11	a	a	DT
cord-002180-gsdk5x3e	175	12	Norwalk	Norwalk	NNP
cord-002180-gsdk5x3e	175	13	-	-	HYPH
cord-002180-gsdk5x3e	175	14	like	like	JJ
cord-002180-gsdk5x3e	175	15	virus	virus	NN
cord-002180-gsdk5x3e	175	16	Global	global	JJ
cord-002180-gsdk5x3e	175	17	and	and	CC
cord-002180-gsdk5x3e	175	18	regional	regional	JJ
cord-002180-gsdk5x3e	175	19	mortality	mortality	NN
cord-002180-gsdk5x3e	175	20	from	from	IN
cord-002180-gsdk5x3e	175	21	235	235	CD
cord-002180-gsdk5x3e	175	22	causes	cause	NNS
cord-002180-gsdk5x3e	175	23	of	of	IN
cord-002180-gsdk5x3e	175	24	death	death	NN
cord-002180-gsdk5x3e	175	25	for	for	IN
cord-002180-gsdk5x3e	175	26	20	20	CD
cord-002180-gsdk5x3e	175	27	age	age	NN
cord-002180-gsdk5x3e	175	28	groups	group	NNS
cord-002180-gsdk5x3e	175	29	in	in	IN
cord-002180-gsdk5x3e	175	30	1990	1990	CD
cord-002180-gsdk5x3e	175	31	and	and	CC
cord-002180-gsdk5x3e	175	32	2010	2010	CD
cord-002180-gsdk5x3e	175	33	:	:	:
cord-002180-gsdk5x3e	175	34	a	a	DT
cord-002180-gsdk5x3e	175	35	systematic	systematic	JJ
cord-002180-gsdk5x3e	175	36	analysis	analysis	NN
cord-002180-gsdk5x3e	175	37	for	for	IN
cord-002180-gsdk5x3e	175	38	the	the	DT
cord-002180-gsdk5x3e	175	39	Global	Global	NNP
cord-002180-gsdk5x3e	175	40	Burden	Burden	NNP
cord-002180-gsdk5x3e	175	41	of	of	IN
cord-002180-gsdk5x3e	175	42	Disease	Disease	NNP
cord-002180-gsdk5x3e	175	43	Study	Study	NNP
cord-002180-gsdk5x3e	175	44	Replication	Replication	NNP
cord-002180-gsdk5x3e	175	45	of	of	IN
cord-002180-gsdk5x3e	175	46	Norovirus	norovirus	NN
cord-002180-gsdk5x3e	175	47	in	in	IN
cord-002180-gsdk5x3e	175	48	cell	cell	NN
cord-002180-gsdk5x3e	175	49	culture	culture	NN
cord-002180-gsdk5x3e	175	50	reveals	reveal	VBZ
cord-002180-gsdk5x3e	175	51	a	a	DT
cord-002180-gsdk5x3e	175	52	tropism	tropism	NN
cord-002180-gsdk5x3e	175	53	for	for	IN
cord-002180-gsdk5x3e	175	54	dendritic	dendritic	JJ
cord-002180-gsdk5x3e	175	55	cells	cell	NNS
cord-002180-gsdk5x3e	175	56	and	and	CC
cord-002180-gsdk5x3e	175	57	macrophages	macrophage	NNS
cord-002180-gsdk5x3e	175	58	Cleavage	cleavage	NN
cord-002180-gsdk5x3e	175	59	map	map	NN
cord-002180-gsdk5x3e	175	60	and	and	CC
cord-002180-gsdk5x3e	175	61	proteolytic	proteolytic	JJ
cord-002180-gsdk5x3e	175	62	processing	processing	NN
cord-002180-gsdk5x3e	175	63	of	of	IN
cord-002180-gsdk5x3e	175	64	the	the	DT
cord-002180-gsdk5x3e	175	65	murine	murine	JJ
cord-002180-gsdk5x3e	175	66	norovirus	norovirus	NN
cord-002180-gsdk5x3e	175	67	nonstructural	nonstructural	JJ
cord-002180-gsdk5x3e	175	68	polyprotein	polyprotein	NN
cord-002180-gsdk5x3e	175	69	in	in	IN
cord-002180-gsdk5x3e	175	70	infected	infected	JJ
cord-002180-gsdk5x3e	175	71	cells	cell	NNS
cord-002180-gsdk5x3e	176	1	Norovirus	norovirus	NN
cord-002180-gsdk5x3e	176	2	regulation	regulation	NN
cord-002180-gsdk5x3e	176	3	of	of	IN
cord-002180-gsdk5x3e	176	4	the	the	DT
cord-002180-gsdk5x3e	176	5	innate	innate	JJ
cord-002180-gsdk5x3e	176	6	immune	immune	JJ
cord-002180-gsdk5x3e	176	7	response	response	NN
cord-002180-gsdk5x3e	176	8	and	and	CC
cord-002180-gsdk5x3e	176	9	apoptosis	apoptosis	NN
cord-002180-gsdk5x3e	176	10	occurs	occur	VBZ
cord-002180-gsdk5x3e	176	11	via	via	IN
cord-002180-gsdk5x3e	176	12	the	the	DT
cord-002180-gsdk5x3e	176	13	product	product	NN
cord-002180-gsdk5x3e	176	14	of	of	IN
cord-002180-gsdk5x3e	176	15	the	the	DT
cord-002180-gsdk5x3e	176	16	alternative	alternative	JJ
cord-002180-gsdk5x3e	176	17	open	open	JJ
cord-002180-gsdk5x3e	176	18	reading	reading	NN
cord-002180-gsdk5x3e	176	19	frame	frame	NN
cord-002180-gsdk5x3e	176	20	4	4	CD
cord-002180-gsdk5x3e	176	21	VPg	vpg	NN
cord-002180-gsdk5x3e	176	22	-	-	HYPH
cord-002180-gsdk5x3e	176	23	primed	prime	VBN
cord-002180-gsdk5x3e	176	24	RNA	RNA	NNP
cord-002180-gsdk5x3e	176	25	synthesis	synthesis	NN
cord-002180-gsdk5x3e	176	26	of	of	IN
cord-002180-gsdk5x3e	176	27	norovirus	norovirus	NN
cord-002180-gsdk5x3e	176	28	RNA	RNA	NNP
cord-002180-gsdk5x3e	176	29	-	-	HYPH
cord-002180-gsdk5x3e	176	30	dependent	dependent	JJ
cord-002180-gsdk5x3e	176	31	RNA	RNA	NNP
cord-002180-gsdk5x3e	176	32	polymerases	polymerase	NNS
cord-002180-gsdk5x3e	176	33	by	by	IN
cord-002180-gsdk5x3e	176	34	using	use	VBG
cord-002180-gsdk5x3e	176	35	a	a	DT
cord-002180-gsdk5x3e	176	36	novel	novel	JJ
cord-002180-gsdk5x3e	176	37	cell	cell	NN
cord-002180-gsdk5x3e	176	38	-	-	HYPH
cord-002180-gsdk5x3e	176	39	based	base	VBN
cord-002180-gsdk5x3e	176	40	assay	assay	NN
cord-002180-gsdk5x3e	177	1	Caliciviruses	caliciviruse	NNS
cord-002180-gsdk5x3e	177	2	differ	differ	VBP
cord-002180-gsdk5x3e	177	3	in	in	IN
cord-002180-gsdk5x3e	177	4	their	-PRON-	PRP$
cord-002180-gsdk5x3e	177	5	functional	functional	JJ
cord-002180-gsdk5x3e	177	6	requirements	requirement	NNS
cord-002180-gsdk5x3e	177	7	for	for	IN
cord-002180-gsdk5x3e	177	8	eIF4F	eif4f	CD
cord-002180-gsdk5x3e	177	9	components	component	NNS
cord-002180-gsdk5x3e	178	1	Intrinsic	intrinsic	JJ
cord-002180-gsdk5x3e	178	2	disorder	disorder	NN
cord-002180-gsdk5x3e	178	3	in	in	IN
cord-002180-gsdk5x3e	179	1	Viral	Viral	NNP
cord-002180-gsdk5x3e	179	2	Proteins	Proteins	NNP
cord-002180-gsdk5x3e	179	3	Genome	Genome	NNP
cord-002180-gsdk5x3e	179	4	-	-	HYPH
cord-002180-gsdk5x3e	179	5	Linked	link	VBN
cord-002180-gsdk5x3e	179	6	:	:	:
cord-002180-gsdk5x3e	179	7	experimental	experimental	JJ
cord-002180-gsdk5x3e	179	8	and	and	CC
cord-002180-gsdk5x3e	179	9	predictive	predictive	JJ
cord-002180-gsdk5x3e	179	10	analyses	analysis	NNS
cord-002180-gsdk5x3e	180	1	Characterisation	Characterisation	NNP
cord-002180-gsdk5x3e	180	2	of	of	IN
cord-002180-gsdk5x3e	180	3	the	the	DT
cord-002180-gsdk5x3e	180	4	NS1	ns1	NN
cord-002180-gsdk5x3e	180	5	-	-	HYPH
cord-002180-gsdk5x3e	180	6	2	2	CD
cord-002180-gsdk5x3e	180	7	and	and	CC
cord-002180-gsdk5x3e	180	8	NS4	NS4	NNP
cord-002180-gsdk5x3e	180	9	proteins	protein	NNS
cord-002180-gsdk5x3e	180	10	of	of	IN
cord-002180-gsdk5x3e	180	11	murine	murine	JJ
cord-002180-gsdk5x3e	180	12	norovirus	norovirus	NN
cord-002180-gsdk5x3e	180	13	Influenza	Influenza	NNP
cord-002180-gsdk5x3e	180	14	A	a	DT
cord-002180-gsdk5x3e	180	15	virus	virus	NN
cord-002180-gsdk5x3e	180	16	replication	replication	NN
cord-002180-gsdk5x3e	180	17	induces	induce	VBZ
cord-002180-gsdk5x3e	180	18	cell	cell	NN
cord-002180-gsdk5x3e	180	19	cycle	cycle	NN
cord-002180-gsdk5x3e	180	20	arrest	arrest	NN
cord-002180-gsdk5x3e	180	21	in	in	IN
cord-002180-gsdk5x3e	180	22	G0	G0	NNP
cord-002180-gsdk5x3e	180	23	/	/	SYM
cord-002180-gsdk5x3e	180	24	G1	G1	NNP
cord-002180-gsdk5x3e	180	25	phase	phase	NN
cord-002180-gsdk5x3e	180	26	Cell	cell	NN
cord-002180-gsdk5x3e	180	27	cycle	cycle	NN
cord-002180-gsdk5x3e	180	28	arrest	arrest	NN
cord-002180-gsdk5x3e	180	29	by	by	IN
cord-002180-gsdk5x3e	180	30	transforming	transform	VBG
cord-002180-gsdk5x3e	180	31	growth	growth	NN
cord-002180-gsdk5x3e	180	32	factor	factor	NN
cord-002180-gsdk5x3e	181	1	beta1	beta1	NN
cord-002180-gsdk5x3e	181	2	enhances	enhance	VBZ
cord-002180-gsdk5x3e	181	3	replication	replication	NN
cord-002180-gsdk5x3e	181	4	of	of	IN
cord-002180-gsdk5x3e	181	5	respiratory	respiratory	JJ
cord-002180-gsdk5x3e	181	6	syncytial	syncytial	JJ
cord-002180-gsdk5x3e	181	7	virus	virus	NN
cord-002180-gsdk5x3e	181	8	in	in	IN
cord-002180-gsdk5x3e	181	9	lung	lung	NN
cord-002180-gsdk5x3e	181	10	epithelial	epithelial	NN
cord-002180-gsdk5x3e	181	11	cells	cell	NNS
cord-002180-gsdk5x3e	181	12	Cell	cell	NN
cord-002180-gsdk5x3e	181	13	cycle	cycle	NN
cord-002180-gsdk5x3e	181	14	arrest	arrest	NN
cord-002180-gsdk5x3e	181	15	during	during	IN
cord-002180-gsdk5x3e	181	16	measles	measles	NNP
cord-002180-gsdk5x3e	181	17	virus	virus	NN
cord-002180-gsdk5x3e	181	18	infection	infection	NN
cord-002180-gsdk5x3e	181	19	:	:	:
cord-002180-gsdk5x3e	181	20	a	a	DT
cord-002180-gsdk5x3e	181	21	G0-like	g0-like	NN
cord-002180-gsdk5x3e	181	22	block	block	NN
cord-002180-gsdk5x3e	181	23	leads	lead	NNS
cord-002180-gsdk5x3e	181	24	to	to	IN
cord-002180-gsdk5x3e	181	25	suppression	suppression	NN
cord-002180-gsdk5x3e	181	26	of	of	IN
cord-002180-gsdk5x3e	181	27	retinoblastoma	retinoblastoma	NN
cord-002180-gsdk5x3e	181	28	protein	protein	NN
cord-002180-gsdk5x3e	181	29	expression	expression	NN
cord-002180-gsdk5x3e	181	30	Cell	Cell	NNP
cord-002180-gsdk5x3e	181	31	cycle	cycle	NN
cord-002180-gsdk5x3e	181	32	status	status	NN
cord-002180-gsdk5x3e	181	33	affects	affect	VBZ
cord-002180-gsdk5x3e	181	34	coxsackievirus	coxsackievirus	NNP
cord-002180-gsdk5x3e	181	35	replication	replication	NN
cord-002180-gsdk5x3e	181	36	,	,	,
cord-002180-gsdk5x3e	181	37	persistence	persistence	NN
cord-002180-gsdk5x3e	181	38	,	,	,
cord-002180-gsdk5x3e	181	39	and	and	CC
cord-002180-gsdk5x3e	181	40	reactivation	reactivation	NN
cord-002180-gsdk5x3e	181	41	in	in	IN
cord-002180-gsdk5x3e	181	42	vitro	vitro	FW
cord-002180-gsdk5x3e	182	1	Murine	murine	JJ
cord-002180-gsdk5x3e	182	2	coronavirus	coronavirus	NN
cord-002180-gsdk5x3e	182	3	replication	replication	NN
cord-002180-gsdk5x3e	182	4	induces	induce	VBZ
cord-002180-gsdk5x3e	182	5	cell	cell	NN
cord-002180-gsdk5x3e	182	6	cycle	cycle	NN
cord-002180-gsdk5x3e	182	7	arrest	arrest	NN
cord-002180-gsdk5x3e	182	8	in	in	IN
cord-002180-gsdk5x3e	182	9	G0	G0	NNP
cord-002180-gsdk5x3e	182	10	/	/	SYM
cord-002180-gsdk5x3e	182	11	G1	G1	NNP
cord-002180-gsdk5x3e	182	12	phase	phase	NN
cord-002180-gsdk5x3e	183	1	The	the	DT
cord-002180-gsdk5x3e	183	2	nucleocapsid	nucleocapsid	NN
cord-002180-gsdk5x3e	183	3	protein	protein	NN
cord-002180-gsdk5x3e	183	4	of	of	IN
cord-002180-gsdk5x3e	183	5	severe	severe	JJ
cord-002180-gsdk5x3e	183	6	acute	acute	JJ
cord-002180-gsdk5x3e	183	7	respiratory	respiratory	JJ
cord-002180-gsdk5x3e	183	8	syndrome	syndrome	NN
cord-002180-gsdk5x3e	183	9	-	-	HYPH
cord-002180-gsdk5x3e	183	10	coronavirus	coronavirus	NN
cord-002180-gsdk5x3e	183	11	inhibits	inhibit	VBZ
cord-002180-gsdk5x3e	183	12	the	the	DT
cord-002180-gsdk5x3e	183	13	activity	activity	NN
cord-002180-gsdk5x3e	183	14	of	of	IN
cord-002180-gsdk5x3e	183	15	cyclin	cyclin	JJ
cord-002180-gsdk5x3e	183	16	-	-	HYPH
cord-002180-gsdk5x3e	183	17	cyclin	cyclin	NN
cord-002180-gsdk5x3e	183	18	-	-	HYPH
cord-002180-gsdk5x3e	183	19	dependent	dependent	JJ
cord-002180-gsdk5x3e	183	20	kinase	kinase	NN
cord-002180-gsdk5x3e	183	21	complex	complex	NN
cord-002180-gsdk5x3e	183	22	and	and	CC
cord-002180-gsdk5x3e	183	23	blocks	block	VBZ
cord-002180-gsdk5x3e	183	24	S	s	NN
cord-002180-gsdk5x3e	183	25	phase	phase	NN
cord-002180-gsdk5x3e	183	26	progression	progression	NN
cord-002180-gsdk5x3e	183	27	in	in	IN
cord-002180-gsdk5x3e	183	28	mammalian	mammalian	JJ
cord-002180-gsdk5x3e	183	29	cells	cell	NNS
cord-002180-gsdk5x3e	184	1	Murine	murine	JJ
cord-002180-gsdk5x3e	184	2	Norovirus	Norovirus	NNP
cord-002180-gsdk5x3e	184	3	replication	replication	NN
cord-002180-gsdk5x3e	184	4	induces	induce	VBZ
cord-002180-gsdk5x3e	184	5	a	a	DT
cord-002180-gsdk5x3e	184	6	G0	G0	NNP
cord-002180-gsdk5x3e	184	7	/	/	SYM
cord-002180-gsdk5x3e	184	8	G1	G1	NNP
cord-002180-gsdk5x3e	184	9	cell	cell	NN
cord-002180-gsdk5x3e	184	10	cycle	cycle	NN
cord-002180-gsdk5x3e	184	11	arrest	arrest	NN
cord-002180-gsdk5x3e	184	12	in	in	IN
cord-002180-gsdk5x3e	184	13	asynchronous	asynchronous	JJ
cord-002180-gsdk5x3e	184	14	growing	growing	NN
cord-002180-gsdk5x3e	184	15	cells	cell	NNS
cord-002180-gsdk5x3e	184	16	Mammalian	mammalian	JJ
cord-002180-gsdk5x3e	184	17	cell	cell	NN
cord-002180-gsdk5x3e	184	18	-	-	HYPH
cord-002180-gsdk5x3e	184	19	cycle	cycle	NN
cord-002180-gsdk5x3e	184	20	regulation	regulation	NN
cord-002180-gsdk5x3e	184	21	:	:	:
cord-002180-gsdk5x3e	184	22	several	several	JJ
cord-002180-gsdk5x3e	184	23	Cdks	Cdks	NNP
cord-002180-gsdk5x3e	184	24	,	,	,
cord-002180-gsdk5x3e	184	25	numerous	numerous	JJ
cord-002180-gsdk5x3e	184	26	cyclins	cyclin	NNS
cord-002180-gsdk5x3e	184	27	and	and	CC
cord-002180-gsdk5x3e	184	28	diverse	diverse	JJ
cord-002180-gsdk5x3e	184	29	compensatory	compensatory	JJ
cord-002180-gsdk5x3e	184	30	mechanisms	mechanism	NNS
cord-002180-gsdk5x3e	184	31	Regulation	regulation	NN
cord-002180-gsdk5x3e	184	32	of	of	IN
cord-002180-gsdk5x3e	184	33	cyclin	cyclin	NN
cord-002180-gsdk5x3e	184	34	-	-	HYPH
cord-002180-gsdk5x3e	184	35	Cdk	Cdk	NNP
cord-002180-gsdk5x3e	184	36	activity	activity	NN
cord-002180-gsdk5x3e	184	37	in	in	IN
cord-002180-gsdk5x3e	184	38	mammalian	mammalian	JJ
cord-002180-gsdk5x3e	184	39	cells	cell	NNS
cord-002180-gsdk5x3e	184	40	Functional	functional	JJ
cord-002180-gsdk5x3e	184	41	inactivation	inactivation	NN
cord-002180-gsdk5x3e	184	42	of	of	IN
cord-002180-gsdk5x3e	184	43	the	the	DT
cord-002180-gsdk5x3e	184	44	retinoblastoma	retinoblastoma	NN
cord-002180-gsdk5x3e	184	45	protein	protein	NN
cord-002180-gsdk5x3e	184	46	requires	require	VBZ
cord-002180-gsdk5x3e	184	47	sequential	sequential	JJ
cord-002180-gsdk5x3e	184	48	modification	modification	NN
cord-002180-gsdk5x3e	184	49	by	by	IN
cord-002180-gsdk5x3e	184	50	at	at	RB
cord-002180-gsdk5x3e	184	51	least	least	JJS
cord-002180-gsdk5x3e	184	52	two	two	CD
cord-002180-gsdk5x3e	184	53	distinct	distinct	JJ
cord-002180-gsdk5x3e	184	54	cyclin	cyclin	NN
cord-002180-gsdk5x3e	184	55	-	-	HYPH
cord-002180-gsdk5x3e	184	56	cdk	cdk	NNP
cord-002180-gsdk5x3e	184	57	complexes	complex	NNS
cord-002180-gsdk5x3e	185	1	Human	human	JJ
cord-002180-gsdk5x3e	185	2	cyclin	cyclin	NN
cord-002180-gsdk5x3e	185	3	A	A	NNP
cord-002180-gsdk5x3e	185	4	is	be	VBZ
cord-002180-gsdk5x3e	185	5	required	require	VBN
cord-002180-gsdk5x3e	185	6	for	for	IN
cord-002180-gsdk5x3e	185	7	mitosis	mitosis	NN
cord-002180-gsdk5x3e	185	8	until	until	IN
cord-002180-gsdk5x3e	185	9	mid	mid	JJ
cord-002180-gsdk5x3e	185	10	prophase	prophase	NN
cord-002180-gsdk5x3e	185	11	Distinct	distinct	JJ
cord-002180-gsdk5x3e	185	12	roles	role	NNS
cord-002180-gsdk5x3e	185	13	for	for	IN
cord-002180-gsdk5x3e	185	14	cyclins	cyclin	NNS
cord-002180-gsdk5x3e	185	15	E	e	NN
cord-002180-gsdk5x3e	185	16	and	and	CC
cord-002180-gsdk5x3e	185	17	A	a	NN
cord-002180-gsdk5x3e	185	18	during	during	IN
cord-002180-gsdk5x3e	185	19	DNA	dna	NN
cord-002180-gsdk5x3e	185	20	replication	replication	NN
cord-002180-gsdk5x3e	185	21	complex	complex	JJ
cord-002180-gsdk5x3e	185	22	assembly	assembly	NN
cord-002180-gsdk5x3e	185	23	and	and	CC
cord-002180-gsdk5x3e	185	24	activation	activation	NN
cord-002180-gsdk5x3e	185	25	Recovery	recovery	NN
cord-002180-gsdk5x3e	185	26	of	of	IN
cord-002180-gsdk5x3e	185	27	infectious	infectious	JJ
cord-002180-gsdk5x3e	185	28	murine	murine	JJ
cord-002180-gsdk5x3e	185	29	norovirus	norovirus	NN
cord-002180-gsdk5x3e	185	30	using	use	VBG
cord-002180-gsdk5x3e	185	31	pol	pol	NNP
cord-002180-gsdk5x3e	185	32	II	II	NNP
cord-002180-gsdk5x3e	185	33	-	-	HYPH
cord-002180-gsdk5x3e	185	34	driven	drive	VBN
cord-002180-gsdk5x3e	185	35	expression	expression	NN
cord-002180-gsdk5x3e	185	36	of	of	IN
cord-002180-gsdk5x3e	185	37	full	full	JJ
cord-002180-gsdk5x3e	185	38	-	-	HYPH
cord-002180-gsdk5x3e	185	39	length	length	NN
cord-002180-gsdk5x3e	185	40	cDNA	cdna	NN
cord-002180-gsdk5x3e	185	41	Efficient	Efficient	NNP
cord-002180-gsdk5x3e	185	42	RNA	RNA	NNP
cord-002180-gsdk5x3e	185	43	/	/	SYM
cord-002180-gsdk5x3e	185	44	Cas9-mediated	cas9-mediate	VBN
cord-002180-gsdk5x3e	185	45	genome	genome	NN
cord-002180-gsdk5x3e	185	46	editing	editing	NN
cord-002180-gsdk5x3e	185	47	in	in	IN
cord-002180-gsdk5x3e	185	48	Xenopus	Xenopus	NNP
cord-002180-gsdk5x3e	185	49	tropicalis	tropicalis	NNP
cord-002180-gsdk5x3e	185	50	Cell	Cell	NNP
cord-002180-gsdk5x3e	185	51	synchronization	synchronization	NN
cord-002180-gsdk5x3e	185	52	effect	effect	NN
cord-002180-gsdk5x3e	185	53	on	on	IN
cord-002180-gsdk5x3e	185	54	mammalian	mammalian	JJ
cord-002180-gsdk5x3e	185	55	cell	cell	NN
cord-002180-gsdk5x3e	185	56	permeabilization	permeabilization	NN
cord-002180-gsdk5x3e	185	57	and	and	CC
cord-002180-gsdk5x3e	185	58	gene	gene	NN
cord-002180-gsdk5x3e	185	59	delivery	delivery	NN
cord-002180-gsdk5x3e	185	60	by	by	IN
cord-002180-gsdk5x3e	185	61	electric	electric	JJ
cord-002180-gsdk5x3e	185	62	field	field	NN
cord-002180-gsdk5x3e	185	63	Norovirus	Norovirus	NNP
cord-002180-gsdk5x3e	185	64	translation	translation	NN
cord-002180-gsdk5x3e	185	65	requires	require	VBZ
cord-002180-gsdk5x3e	185	66	an	an	DT
cord-002180-gsdk5x3e	185	67	interaction	interaction	NN
cord-002180-gsdk5x3e	185	68	between	between	IN
cord-002180-gsdk5x3e	185	69	the	the	DT
cord-002180-gsdk5x3e	185	70	C	C	NNP
cord-002180-gsdk5x3e	185	71	Terminus	Terminus	NNP
cord-002180-gsdk5x3e	185	72	of	of	IN
cord-002180-gsdk5x3e	185	73	the	the	DT
cord-002180-gsdk5x3e	185	74	genome	genome	NN
cord-002180-gsdk5x3e	185	75	-	-	HYPH
cord-002180-gsdk5x3e	185	76	linked	link	VBN
cord-002180-gsdk5x3e	185	77	viral	viral	JJ
cord-002180-gsdk5x3e	185	78	protein	protein	NN
cord-002180-gsdk5x3e	185	79	VPg	VPg	NNS
cord-002180-gsdk5x3e	185	80	and	and	CC
cord-002180-gsdk5x3e	185	81	eukaryotic	eukaryotic	JJ
cord-002180-gsdk5x3e	185	82	translation	translation	NN
cord-002180-gsdk5x3e	185	83	initiation	initiation	NN
cord-002180-gsdk5x3e	185	84	factor	factor	NN
cord-002180-gsdk5x3e	186	1	4	4	CD
cord-002180-gsdk5x3e	186	2	G	G	NNP
cord-002180-gsdk5x3e	186	3	Human	Human	NNP
cord-002180-gsdk5x3e	186	4	cytomegalovirus	cytomegalovirus	NN
cord-002180-gsdk5x3e	186	5	inhibits	inhibit	VBZ
cord-002180-gsdk5x3e	186	6	cellular	cellular	JJ
cord-002180-gsdk5x3e	186	7	DNA	dna	NN
cord-002180-gsdk5x3e	186	8	synthesis	synthesis	NN
cord-002180-gsdk5x3e	186	9	and	and	CC
cord-002180-gsdk5x3e	186	10	arrests	arrest	NNS
cord-002180-gsdk5x3e	186	11	productively	productively	RB
cord-002180-gsdk5x3e	186	12	infected	infected	JJ
cord-002180-gsdk5x3e	186	13	cells	cell	NNS
cord-002180-gsdk5x3e	186	14	in	in	IN
cord-002180-gsdk5x3e	186	15	late	late	JJ
cord-002180-gsdk5x3e	186	16	G1	G1	NNP
cord-002180-gsdk5x3e	186	17	Herpes	Herpes	NNP
cord-002180-gsdk5x3e	186	18	simplex	simplex	NN
cord-002180-gsdk5x3e	186	19	virus	virus	NN
cord-002180-gsdk5x3e	186	20	type	type	NN
cord-002180-gsdk5x3e	186	21	1	1	CD
cord-002180-gsdk5x3e	186	22	infection	infection	NN
cord-002180-gsdk5x3e	186	23	imposes	impose	VBZ
cord-002180-gsdk5x3e	186	24	a	a	DT
cord-002180-gsdk5x3e	186	25	G(1)/S	G(1)/S	NNP
cord-002180-gsdk5x3e	186	26	block	block	NN
cord-002180-gsdk5x3e	186	27	in	in	IN
cord-002180-gsdk5x3e	186	28	asynchronously	asynchronously	RB
cord-002180-gsdk5x3e	186	29	growing	grow	VBG
cord-002180-gsdk5x3e	186	30	cells	cell	NNS
cord-002180-gsdk5x3e	186	31	and	and	CC
cord-002180-gsdk5x3e	186	32	prevents	prevent	VBZ
cord-002180-gsdk5x3e	186	33	G(1	G(1	NNS
cord-002180-gsdk5x3e	186	34	)	)	-RRB-
cord-002180-gsdk5x3e	186	35	entry	entry	NN
cord-002180-gsdk5x3e	186	36	in	in	IN
cord-002180-gsdk5x3e	186	37	quiescent	quiescent	JJ
cord-002180-gsdk5x3e	186	38	cells	cell	NNS
cord-002180-gsdk5x3e	186	39	VPg	VPg	NNS
cord-002180-gsdk5x3e	186	40	of	of	IN
cord-002180-gsdk5x3e	186	41	murine	murine	JJ
cord-002180-gsdk5x3e	186	42	norovirus	norovirus	NN
cord-002180-gsdk5x3e	186	43	binds	bind	VBZ
cord-002180-gsdk5x3e	186	44	translation	translation	NN
cord-002180-gsdk5x3e	186	45	initiation	initiation	NN
cord-002180-gsdk5x3e	186	46	factors	factor	NNS
cord-002180-gsdk5x3e	186	47	in	in	IN
cord-002180-gsdk5x3e	186	48	infected	infected	JJ
cord-002180-gsdk5x3e	186	49	cells	cell	NNS
cord-002180-gsdk5x3e	186	50	Potyviral	Potyviral	NNP
cord-002180-gsdk5x3e	186	51	VPg	VPg	NNS
cord-002180-gsdk5x3e	186	52	enhances	enhance	VBZ
cord-002180-gsdk5x3e	186	53	viral	viral	JJ
cord-002180-gsdk5x3e	186	54	RNA	RNA	NNP
cord-002180-gsdk5x3e	186	55	Translation	Translation	NNP
cord-002180-gsdk5x3e	186	56	and	and	CC
cord-002180-gsdk5x3e	186	57	inhibits	inhibit	VBZ
cord-002180-gsdk5x3e	186	58	reporter	reporter	NN
cord-002180-gsdk5x3e	186	59	mRNA	mrna	NN
cord-002180-gsdk5x3e	186	60	translation	translation	NN
cord-002180-gsdk5x3e	186	61	in	in	IN
cord-002180-gsdk5x3e	186	62	planta	planta	NNP
cord-002180-gsdk5x3e	186	63	Nucleotidylylation	Nucleotidylylation	NNP
cord-002180-gsdk5x3e	186	64	of	of	IN
cord-002180-gsdk5x3e	186	65	the	the	DT
cord-002180-gsdk5x3e	186	66	VPg	VPg	NNS
cord-002180-gsdk5x3e	186	67	protein	protein	NN
cord-002180-gsdk5x3e	186	68	of	of	IN
cord-002180-gsdk5x3e	186	69	a	a	DT
cord-002180-gsdk5x3e	186	70	human	human	JJ
cord-002180-gsdk5x3e	186	71	norovirus	norovirus	NN
cord-002180-gsdk5x3e	186	72	by	by	IN
cord-002180-gsdk5x3e	186	73	its	-PRON-	PRP$
cord-002180-gsdk5x3e	186	74	proteinase	proteinase	NN
cord-002180-gsdk5x3e	186	75	-	-	HYPH
cord-002180-gsdk5x3e	186	76	polymerase	polymerase	NN
cord-002180-gsdk5x3e	186	77	precursor	precursor	NN
cord-002180-gsdk5x3e	186	78	protein	protein	NN
cord-002180-gsdk5x3e	187	1	The	the	DT
cord-002180-gsdk5x3e	187	2	genome	genome	NN
cord-002180-gsdk5x3e	187	3	-	-	HYPH
cord-002180-gsdk5x3e	187	4	linked	link	VBN
cord-002180-gsdk5x3e	187	5	protein	protein	NN
cord-002180-gsdk5x3e	187	6	VPg	VPg	NNS
cord-002180-gsdk5x3e	187	7	of	of	IN
cord-002180-gsdk5x3e	187	8	vertebrate	vertebrate	JJ
cord-002180-gsdk5x3e	187	9	viruses	virus	NNS
cord-002180-gsdk5x3e	187	10	-	-	:
cord-002180-gsdk5x3e	187	11	a	a	DT
cord-002180-gsdk5x3e	187	12	multifaceted	multifaceted	JJ
cord-002180-gsdk5x3e	187	13	protein	protein	NN
cord-002180-gsdk5x3e	187	14	Structures	structure	NNS
cord-002180-gsdk5x3e	187	15	of	of	IN
cord-002180-gsdk5x3e	187	16	the	the	DT
cord-002180-gsdk5x3e	187	17	compact	compact	JJ
cord-002180-gsdk5x3e	187	18	helical	helical	JJ
cord-002180-gsdk5x3e	187	19	core	core	NN
cord-002180-gsdk5x3e	187	20	domains	domain	NNS
cord-002180-gsdk5x3e	187	21	of	of	IN
cord-002180-gsdk5x3e	187	22	feline	feline	JJ
cord-002180-gsdk5x3e	187	23	calicivirus	calicivirus	NN
cord-002180-gsdk5x3e	187	24	and	and	CC
cord-002180-gsdk5x3e	187	25	murine	murine	JJ
cord-002180-gsdk5x3e	187	26	norovirus	norovirus	NN
cord-002180-gsdk5x3e	187	27	VPg	VPg	NNS
cord-002180-gsdk5x3e	187	28	proteins	protein	NNS
cord-002180-gsdk5x3e	188	1	Calicivirus	calicivirus	JJ
cord-002180-gsdk5x3e	188	2	translation	translation	NN
cord-002180-gsdk5x3e	188	3	initiation	initiation	NN
cord-002180-gsdk5x3e	188	4	requires	require	VBZ
cord-002180-gsdk5x3e	188	5	an	an	DT
cord-002180-gsdk5x3e	188	6	interaction	interaction	NN
cord-002180-gsdk5x3e	188	7	between	between	IN
cord-002180-gsdk5x3e	188	8	VPg	VPg	NNS
cord-002180-gsdk5x3e	188	9	and	and	CC
cord-002180-gsdk5x3e	188	10	eIF	eif	JJ
cord-002180-gsdk5x3e	188	11	4	4	CD
cord-002180-gsdk5x3e	188	12	E	E	NNP
cord-002180-gsdk5x3e	188	13	Sapovirus	Sapovirus	NNP
cord-002180-gsdk5x3e	188	14	translation	translation	NN
cord-002180-gsdk5x3e	188	15	requires	require	VBZ
cord-002180-gsdk5x3e	188	16	an	an	DT
cord-002180-gsdk5x3e	188	17	interaction	interaction	NN
cord-002180-gsdk5x3e	188	18	between	between	IN
cord-002180-gsdk5x3e	188	19	VPg	VPg	NNS
cord-002180-gsdk5x3e	188	20	and	and	CC
cord-002180-gsdk5x3e	188	21	the	the	DT
cord-002180-gsdk5x3e	188	22	cap	cap	NN
cord-002180-gsdk5x3e	188	23	binding	bind	VBG
cord-002180-gsdk5x3e	188	24	protein	protein	NN
cord-002180-gsdk5x3e	188	25	eIF4E	eif4e	CD
cord-002180-gsdk5x3e	188	26	The	the	DT
cord-002180-gsdk5x3e	188	27	genome	genome	NN
cord-002180-gsdk5x3e	188	28	-	-	HYPH
cord-002180-gsdk5x3e	188	29	linked	link	VBN
cord-002180-gsdk5x3e	188	30	protein	protein	NN
cord-002180-gsdk5x3e	188	31	VPg	VPg	NNS
cord-002180-gsdk5x3e	188	32	of	of	IN
cord-002180-gsdk5x3e	188	33	the	the	DT
cord-002180-gsdk5x3e	188	34	Norwalk	Norwalk	NNP
cord-002180-gsdk5x3e	188	35	virus	virus	NN
cord-002180-gsdk5x3e	188	36	binds	bind	VBZ
cord-002180-gsdk5x3e	188	37	eIF3	eIF3	NNP
cord-002180-gsdk5x3e	188	38	,	,	,
cord-002180-gsdk5x3e	188	39	suggesting	suggest	VBG
cord-002180-gsdk5x3e	188	40	its	-PRON-	PRP$
cord-002180-gsdk5x3e	188	41	role	role	NN
cord-002180-gsdk5x3e	188	42	in	in	IN
cord-002180-gsdk5x3e	188	43	translation	translation	NN
cord-002180-gsdk5x3e	188	44	initiation	initiation	NN
cord-002180-gsdk5x3e	188	45	complex	complex	JJ
cord-002180-gsdk5x3e	188	46	recruitment	recruitment	NN
cord-002180-gsdk5x3e	188	47	Rapamycin	Rapamycin	NNP
cord-002180-gsdk5x3e	188	48	stimulates	stimulate	VBZ
cord-002180-gsdk5x3e	188	49	viral	viral	JJ
cord-002180-gsdk5x3e	188	50	protein	protein	NN
cord-002180-gsdk5x3e	188	51	synthesis	synthesis	NN
cord-002180-gsdk5x3e	188	52	and	and	CC
cord-002180-gsdk5x3e	188	53	augments	augment	VBZ
cord-002180-gsdk5x3e	188	54	the	the	DT
cord-002180-gsdk5x3e	188	55	shutoff	shutoff	NN
cord-002180-gsdk5x3e	188	56	of	of	IN
cord-002180-gsdk5x3e	188	57	host	host	NN
cord-002180-gsdk5x3e	188	58	protein	protein	NN
cord-002180-gsdk5x3e	188	59	synthesis	synthesis	NN
cord-002180-gsdk5x3e	188	60	upon	upon	IN
cord-002180-gsdk5x3e	188	61	picornavirus	picornavirus	NNP
cord-002180-gsdk5x3e	188	62	infection	infection	NN
cord-002180-gsdk5x3e	188	63	Avian	Avian	NNP
cord-002180-gsdk5x3e	188	64	reovirus	reovirus	VBP
cord-002180-gsdk5x3e	188	65	nonstructural	nonstructural	JJ
cord-002180-gsdk5x3e	188	66	protein	protein	NN
cord-002180-gsdk5x3e	188	67	p17-induced	p17-induced	CD
cord-002180-gsdk5x3e	188	68	G(2)/	g(2)/	NN
cord-002180-gsdk5x3e	188	69	M	M	NNP
cord-002180-gsdk5x3e	188	70	cell	cell	NN
cord-002180-gsdk5x3e	188	71	cycle	cycle	NN
cord-002180-gsdk5x3e	188	72	arrest	arrest	NN
cord-002180-gsdk5x3e	188	73	and	and	CC
cord-002180-gsdk5x3e	188	74	host	host	VB
cord-002180-gsdk5x3e	188	75	cellular	cellular	JJ
cord-002180-gsdk5x3e	188	76	protein	protein	NN
cord-002180-gsdk5x3e	188	77	translation	translation	NN
cord-002180-gsdk5x3e	188	78	shutoff	shutoff	NN
cord-002180-gsdk5x3e	189	1	involve	involve	VBP
cord-002180-gsdk5x3e	189	2	activation	activation	NN
cord-002180-gsdk5x3e	189	3	of	of	IN
cord-002180-gsdk5x3e	189	4	p53-dependent	p53-dependent	CD
cord-002180-gsdk5x3e	189	5	pathways	pathway	NNS
cord-002180-gsdk5x3e	189	6	Subcellular	Subcellular	NNP
cord-002180-gsdk5x3e	189	7	localization	localization	NN
cord-002180-gsdk5x3e	189	8	of	of	IN
cord-002180-gsdk5x3e	189	9	the	the	DT
cord-002180-gsdk5x3e	189	10	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	189	11	ORF1	ORF1	NNP
cord-002180-gsdk5x3e	189	12	proteins	protein	NNS
cord-002180-gsdk5x3e	189	13	and	and	CC
cord-002180-gsdk5x3e	189	14	their	-PRON-	PRP$
cord-002180-gsdk5x3e	189	15	potential	potential	JJ
cord-002180-gsdk5x3e	189	16	roles	role	NNS
cord-002180-gsdk5x3e	189	17	in	in	IN
cord-002180-gsdk5x3e	189	18	the	the	DT
cord-002180-gsdk5x3e	189	19	formation	formation	NN
cord-002180-gsdk5x3e	189	20	of	of	IN
cord-002180-gsdk5x3e	189	21	the	the	DT
cord-002180-gsdk5x3e	189	22	MNV-1	MNV-1	NNP
cord-002180-gsdk5x3e	189	23	replication	replication	NN
cord-002180-gsdk5x3e	189	24	complex	complex	JJ
cord-002180-gsdk5x3e	189	25	Special	special	JJ
cord-002180-gsdk5x3e	189	26	thanks	thank	NNS
cord-002180-gsdk5x3e	189	27	to	to	IN
cord-002180-gsdk5x3e	189	28	Dr	Dr	NNP
cord-002180-gsdk5x3e	189	29	Estelle	Estelle	NNP
cord-002180-gsdk5x3e	189	30	Baker	Baker	NNP
cord-002180-gsdk5x3e	189	31	and	and	CC
cord-002180-gsdk5x3e	189	32	Joanna	Joanna	NNP
cord-002180-gsdk5x3e	189	33	Ward	Ward	NNP
cord-002180-gsdk5x3e	189	34	for	for	IN
cord-002180-gsdk5x3e	189	35	generation	generation	NN
cord-002180-gsdk5x3e	189	36	of	of	IN
cord-002180-gsdk5x3e	189	37	the	the	DT
cord-002180-gsdk5x3e	189	38	wild	wild	JJ
cord-002180-gsdk5x3e	189	39	-	-	HYPH
cord-002180-gsdk5x3e	189	40	type	type	NN
cord-002180-gsdk5x3e	189	41	NS1	ns1	NN
cord-002180-gsdk5x3e	189	42	-	-	HYPH
cord-002180-gsdk5x3e	189	43	2	2	CD
cord-002180-gsdk5x3e	189	44	and	and	CC
cord-002180-gsdk5x3e	189	45	NS5	ns5	JJ
cord-002180-gsdk5x3e	189	46	plasmids	plasmid	NNS
cord-002180-gsdk5x3e	189	47	.	.	.