id author title date pages extension mime words sentences flesch summary cache txt cord-352447-bc1pf272 Nishida, Yu Novel prognostic biomarkers of pouchitis after ileal pouch-anal anastomosis for ulcerative colitis: Neutrophil-to-lymphocyte ratio 2020-10-26 .txt text/plain 3481 197 47 Despite conflicting results, the development of pouchitis in patients with UC, as reported in several studies, has been linked to various factors, including primary sclerosing cholangitis [2, 4] , other extraintestinal manifestations of inflammatory bowel disease [4, 8, 9] , young age at UC diagnosis [4] , preoperative terminal ileal inflammation [10, 11] , extensive colonic disease [10], presence of interleukin-1 receptor antagonist gene allele 2 [12] , total steroid dose of > 10000 mg [13] , use of infliximab [14] , neutrophil percentage of > 65% [13] , and presence of perinuclear antineutrophil cytoplasmic antibodies [15, 16] . Therefore, our study aimed to evaluate the clinical utility of the NLR for predicting the development of pouchitis after IPAA in patients with UC. Third, we were unable to evaluate the reported pouchitis predictive factors, such as extraintestinal manifestations of inflammatory bowel disease, preoperative terminal ileal inflammation, the presence of interleukin-1 receptor antagonist gene allele 2, total steroid dose of >10000 mg, or presence of perinuclear antineutrophil cytoplasmic antibodies owing to the retrospective design of the study. ./cache/cord-352447-bc1pf272.txt ./txt/cord-352447-bc1pf272.txt