id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-346089-u31n0qxa	McDade, Thomas W.	High seroprevalence for SARS-CoV-2 among household members of essential workers detected using a dried blood spot assay	2020-08-14		.txt	text/plain	2232	140	52	title: High seroprevalence for SARS-CoV-2 among household members of essential workers detected using a dried blood spot assay To address this problem we developed a serological test for SARS-CoV-2 IgG antibodies that requires only a single drop of finger stick capillary whole blood, collected in the home and dried on filter paper (dried blood spot, DBS). Serological testing for SARS-CoV-2 IgG antibodies in DBS samples can facilitate seroprevalence assessment in community settings to address epidemiological questions, monitor duration of antibody responses, and assess if antibodies against the spike protein correlate with protection from reinfection. In addition, we demonstrate the feasibility and utility of quantifying SARS-CoV-2 antibodies in self-collected DBS with results from a community-based sample enriched with health care workers. We have validated a DBS assay to facilitate large-scale serological testing of SARS-CoV-2 IgG antibodies, and results from our feasibility study document a high rate of household transmission.	./cache/cord-346089-u31n0qxa.txt	./txt/cord-346089-u31n0qxa.txt