id author title date pages extension mime words sentences flesch summary cache txt cord-321624-z2mntwef Kowitdamrong, Ekasit Antibody responses to SARS-CoV-2 in patients with differing severities of coronavirus disease 2019 2020-10-09 .txt text/plain 3382 184 57 AIM: To investigate SARS-CoV-2 IgA and IgG antibodies in Thai patients with differing severities of COVID-19. The objective of this study was to investigate the response of IgA and IgG antibodies to SARS--CoV-2 in serial blood samples collected from a population of Thai patients with confirmed COVID-19, and the association of these responses with the severity of the illness. The second subgroup included 49 plasma samples collected from May 1 to May 31, 2020, from patients under investigation (PUI) for COVID-19 with RT-PCR results that were negative for SARS-CoV-2. In the present study, 30% of COVID-19 patients developed positive IgA antibodies very early, within 3 days after the onset of symptoms. In the present study, 20% of the patients with mild symptoms did not develop any IgG antibodies specific to COVID-19, even after 2 weeks after the onset of symptoms. ./cache/cord-321624-z2mntwef.txt ./txt/cord-321624-z2mntwef.txt