id author title date pages extension mime words sentences flesch summary cache txt cord-321438-llnqzkqt Ma, Ruili Proteome Profile of Swine Testicular Cells Infected with Porcine Transmissible Gastroenteritis Coronavirus 2014-10-21 .txt text/plain 7110 310 43 The purpose of this paper was to analyze altered cellular protein levels in porcine transmissible gastroenteritis coronavirus (TGEV)-infected swine testicular (ST) cells in order to determine potential virus-host interactions. To our knowledge, this study is the first time the response profile of ST host cells following TGEV infection has been analyzed using iTRAQ technology, and our description of the late proteomic changes that are occurring after the time of vigorous viral production are novel. Moreover, at the later time point, 64 hpi, our GO term analysis also indicated that a significant number of the differentially expressed proteins were related to cellular stress (p = 8.18E-4), generation of precursor metabolites and energy (p = 2.74E-3), cell motility (p = 6.71E-3), protein complex assembly (p = 4.69E-2), growth (p = 3.87E-2), developmental maturation (p = 1.53E-2), and immune system processes (p = 4.67E-2) ( Table 2) . Prior to proteomic analysis, we determined which time points to investigate following infection by observing the morphological changes and analyzing viral gene expression dynamics in the TGEV infected cells. ./cache/cord-321438-llnqzkqt.txt ./txt/cord-321438-llnqzkqt.txt