id author title date pages extension mime words sentences flesch summary cache txt cord-300859-nqklx0vn Henderson, Kelley C. Specificity and Strain-Typing Capabilities of Nanorod Array-Surface Enhanced Raman Spectroscopy for Mycoplasma pneumoniae Detection 2015-06-29 .txt text/plain 8223 331 41 title: Specificity and Strain-Typing Capabilities of Nanorod Array-Surface Enhanced Raman Spectroscopy for Mycoplasma pneumoniae Detection pneumoniae with statistically significant specificity and sensitivity in simulated and true clinical throat swab samples, and the ability to distinguish between reference strains of the two main genotypes of M. pneumoniae clinical isolates from globally diverse origins and distinguished these from a panel of 12 other human commensal and pathogenic mycoplasma species with 100% cross-validated statistical accuracy. A total of n = 390 pre-processed NA-SERS spectra collected from both substrates were included in the model, consisting of 20 nanorod substrate background spectra, 20 growth medium control spectra, 25 M129 spectra, 25 FH spectra, and 10 spectra per additional clinical isolate. pneumoniae strains from all 12 other human Mollicutes species and the growth medium control with 100% cross-validated sensitivity and specificity (Fig 3A-3C ). ./cache/cord-300859-nqklx0vn.txt ./txt/cord-300859-nqklx0vn.txt