id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-293794-vudufao5	Cuthbertson, Leah	Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children	2019-10-17		.txt	text/plain	4820	255	48	No significant difference in bacterial diversity was observed between samples from those with wheeze and healthy controls. Using 16s rRNA gene sequencing of respiratory samples from children presenting to hospital with acute wheezing, this study aimed to examine whether the bacterial community in the airways of children with acute respiratory wheeze was altered compared with that of nonwheezing children. However, when the microbiota in children with bronchiolitis were compared to those closest in age there was a significant reduction in alpha diversity (richness; p = 0.01, Shannon-Weiner, p = 0.003, inverse Simpsons, p = 0.005) that was not associated with change in bacterial biomass (p = 0.874). When those with a diagnosis of bronchiolitis were compared to other cases that wheezed or age matched control subjects, significant differences in alpha and beta diversity were observed however this may have been driven by subjects with bronchiolitis being significantly younger than other groups of subjects.	./cache/cord-293794-vudufao5.txt	./txt/cord-293794-vudufao5.txt