id author title date pages extension mime words sentences flesch summary cache txt cord-292777-oztmw8jo Wong, Michelle Microbial Translocation Contribute to Febrile Episodes in Adults with Chemotherapy-Induced Neutropenia 2013-07-16 .txt text/plain 3300 179 38 In this study we sought to determine the contribution of microbial translocation to febrile episodes with no attributable microbiological cause (Fever of Unknown Origin, FUO) in an adult febrile neutropaenic cohort. In this study we thus sought to determine the contribution of microbial translocation to FUO episodes in an adult febrile neutropaenic cohort using endotoxin and sCD14 concentrations in the plasma as markers for microbial translocation. In this cohort of iatrogenic neutropaenic adults, we found elevated plasma levels of endotoxin and sCD14 in febrile neutropaenic episodes where no other microbiological findings have been documented, implicating microbial translocation as a potential contributor towards their febrile status. Adding to the field, we have, in our study, in addition to measuring plasma endotoxin concentrations, also measured the host receptor for LPS, sCD14 in an attempt to determine the contribution of microbial translocation to fever as a clinical outcome. ./cache/cord-292777-oztmw8jo.txt ./txt/cord-292777-oztmw8jo.txt