id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-280471-cqypwi5d	Sun, Hua-Bao	The changes of the peripheral CD4+ lymphocytes and inflammatory cytokines in Patients with COVID-19	2020-09-25		.txt	text/plain	4324	202	57	To investigate the clinical value of changes in the subtypes of peripheral blood lymphocytes and levels of inflammatory cytokines in patients with COVID-19, the total numbers of lymphocytes and CD4+ lymphocytes and the ratio of CD4+/CD8+ lymphocytes were calculated and observed in different groups of patients with COVID-19. Characteristic chest CT imaging patterns, positive nucleic acid detection in nasal and throat swab samples, normal or decreased numbers of peripheral white blood cells, decreased numbers of lymphocytes and increased levels of inflammatory cytokines are the key factors in the diagnosis of COVID-19 [3] . The total number of lymphocytes, the percentages of lymphocyte subtypes and the levels of inflammatory cytokines (TNF-α and IL-6) secreted by CD4+ helper T lymphocytes in the peripheral blood were detected by hematology counter and flow cytometer, respectively. In the COVID-19 patients in the general, severe and critical groups, the numbers of peripheral lymphocytes and CD4+ T lymphocytes and the ratio of CD4+/CD8+ lymphocytes were significantly lower than those in the normal control group.	./cache/cord-280471-cqypwi5d.txt	./txt/cord-280471-cqypwi5d.txt