id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-001213-gxqufddb	Butt, Azeem Mehmood	Genome-Wide Analysis of Codon Usage and Influencing Factors in Chikungunya Viruses	2014-03-04		.txt	text/plain	7178	371	54	Therefore, from the similarity index analysis, we observed that selection pressure from hosts and vectors have contributed to shaping the molecular evolution of CHIKV at the respectively, on the formation of the overall codon usage patterns of CHIKV (Figure 2 ). Although, the nucleotide composition correlation analysis showed that codon usage in CHIKV genomes is mainly caused by compositional constraints or mutational pressure, we were interested to determine the possible influence of other factors, such as natural selection. However, in case of CHIKV genomes, variations in nucleotide base compositions were noted (Table 1 ), indicating that other factors, such as natural selection, could also influence overall synonymous codon usage bias. The RSCU values for all the coding sequences of CHIKV genomes were calculated to determine the characteristics of synonymous codon usage without the confounding influence of amino acid composition and the size of coding sequence of different gene samples, following a previously described method [18] .	./cache/cord-001213-gxqufddb.txt	./txt/cord-001213-gxqufddb.txt