id author title date pages extension mime words sentences flesch summary cache txt cord-001126-uqr00nzd Zhang, Zhicheng Synonymous Codon Usage in TTSuV2: Analysis and Comparison with TTSuV1 2013-11-26 .txt text/plain 4902 226 45 In addition, hierarchical cluster analysis of 41 TTSuV2 isolates based on relative synonymous codon usage (RSCU) values suggested that there was no association between geographic distribution and codon bias of TTSuV2 sequences. To explore whether the evolution of codon usage bias in TTSuV2 CDS had been driven by mutation pressure alone or whether translation selection from its host has also contributed, we first compared the correlation between general nucleotide composition (A%, T%, G%, C%, GC%) and nucleotide composition at the third codon position (A 3S %, T 3S %, G 3S %, C 3S %, GC 3S %) using the Spearman's rank correlation analysis method (Table 4) . These results further support the conclusion that composition constraints under mutational bias is an important factor determining synonymous codon usage pattern in TTSuV2, and but that other factors, such as natural selection, contributed. ./cache/cord-001126-uqr00nzd.txt ./txt/cord-001126-uqr00nzd.txt