id author title date pages extension mime words sentences flesch summary cache txt cord-001007-645zegcv Kim, Hak Identification of Recombinant Human Rhinovirus A and C in Circulating Strains from Upper and Lower Respiratory Infections 2013-06-27 .txt text/plain 4060 189 48 This study analyzed parts of the viral genes spanning the 5′ noncoding region (NCR) through to the viral protein (VP) encoding sequences of 105 HRV field isolates from 51 outpatient cases of Acute Respiratory Infectious Network (ARINET) and 54 inpatient cases of severe lower respiratory infection (SLRI) surveillance, in order to identify recombination in field samples. This study aimed to understand and characterize the various recombination events between 5' NCR and VP4/VP2 region of field strains of HRV including species A, B and C, using 105 HRVs identified from two distinctive laboratory surveillance systems, the Acute Respiratory Infectious Network (ARINET) and Severe Lower Respiratory Tract Infections (SLRI) surveillances undertaken from October 2008 to March 2009. In conclusion, this study is the first report describing intraand interspecies genomic recombination in circulating HRV-A and -C isolated from patients with acute or severe respiratory illness and these results will assist in investigating the causes of the diversity and evolution of HRVs arising through recombination events. ./cache/cord-001007-645zegcv.txt ./txt/cord-001007-645zegcv.txt