id author title date pages extension mime words sentences flesch summary cache txt cord-000666-je9t4i6q Verbist, Katherine C. IL-15 Participates in the Respiratory Innate Immune Response to Influenza Virus Infection 2012-05-18 .txt text/plain 7210 302 47 ( Figure 2E) ; however, these animals seemed to regain control of viral replication by day 4 p.i., which perhaps corresponds with the early entry of cells of the adaptive immune response as anti-influenza specific CD8 T cells are first detectable in the lung airways by d6 post infection by flow cytometry ( [34] and data not shown). We observed significant reductions in the numbers of NK cells in the lung airways of influenza-infected animals in which IL-15 was blocked at time points associated with their arrival at the site of infection, and failure of these cell populations to accumulate had implications in early viral control (Figure 2) . doi:10.1371/journal.pone.0037539.g002 frequencies, numbers, CD122 expression, and BrdU incorporation were specific to the lung airways (the sight of treatment), as NK cells isolated from spleens were similar in control and IL-15ctreated animals ( Figure 3C and data not shown). ./cache/cord-000666-je9t4i6q.txt ./txt/cord-000666-je9t4i6q.txt