id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-000539-uh3q65we	Zhang, Yi	Acute Respiratory Distress Syndrome Induced by a Swine 2009 H1N1 Variant in Mice	2012-01-03		.txt	text/plain	4620	247	51	BACKGROUND: Acute respiratory distress syndrome (ARDS) induced by pandemic 2009 H1N1 influenza virus has been widely reported and was considered the main cause of death in critically ill patients with 2009 H1N1 infection. Mice infected with SD/09 virus showed typical ARDS symptoms characterized by 60% lethality on days 8–10 post-inoculation, highly edematous lungs, inflammatory cellular infiltration, alveolar and interstitial edema, lung hemorrhage, progressive and severe hypoxemia, and elevated levels of proinflammatory cytokines and chemokines. In the present mouse model, the number of leukocytes observed in the BALF of virus-infected mice significantly increased compared with the control mice on day 8 p.i. Different counts in BALF showed that the proportion of neutrophils dramatically increased.	./cache/cord-000539-uh3q65we.txt	./txt/cord-000539-uh3q65we.txt