id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-263247-r3t4uowz	Ly, Hinh	Lassa Fever: Viral Replication, Disease Pathogenesis, and Host Immune Modulations	2020-06-03		.txt	text/plain	1121	46	48	In particular, three review articles contributed by leading researchers in the field that cover important concepts, including how different animal models can be developed for understanding Lassa fever's disease pathogenesis and pathologies and for the evaluation of candidate vaccines and antiviral therapies [1] , how to improve the breadth of host immune responses to Lassa vaccination [2] , as well as how different virus and host factors orchestrate the intricate processes of Lassa virus (LASV) entry and genome replication [3] . In addition to these insightful review articles, two research articles deal with novel strategies of developing vaccines for Lassa fever, including the use of the LASV-like particles composed of the viral matrix (Z) and envelope glycoprotein complex (GPC) expressed by the modified vaccinia Ankara virus to protect mice against lethal virus challenges [4] and the use of a candidate LASV vaccine known as ML29 that is composed of the reassorted genome between the pathogenic LASV and the non-pathogenic Mopeia virus (MOPV), which shows its highly attenuated phenotype in rodents [5] .	./cache/cord-263247-r3t4uowz.txt	./txt/cord-263247-r3t4uowz.txt