id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324367-il9mz5na	Rodnina, Marina V	Translational recoding: canonical translation mechanisms reinterpreted	2020-02-20		.txt	text/plain	7396	414	51	This review summarizes the recent advances in understanding the mechanisms of three types of recoding events: stop-codon readthrough, –1 ribosome frameshifting and translational bypassing. In this review, we will focus on three types of recod-ing: (i) stop-codon readthrough; (ii) ribosome frameshifting and (iii) translational bypassing ( Figure 1 ). The key element for recruitment of the SelB-GTP-Sec-tRNA Sec to the stop codon on bacterial ribosomes is a selenocysteine insertion sequence (SECIS) in the mRNA, a SL structure located immediately downstream of the in-frame UGA codon at which Sec is incorporated (67) . A recent crystal structure of a translocation intermediate formed in the absence of EF-G indeed shows that the interactions of the ribosome with the codon-anticodon complex are disrupted and the A-site tRNA in the complex is shifted by one nucleotide toward the -1-frame of the mRNA (78) (Figure 4) .	./cache/cord-324367-il9mz5na.txt	./txt/cord-324367-il9mz5na.txt