id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-280807-0g1uo0rd	Tomani, Jean Claude Didelot	The Inhibition of NLRP3 Inflammasome and IL-6 Production by Hibiscus noldeae Baker f. Derived Constituents Provides a Link to Its Anti-Inflammatory Therapeutic Potentials	2020-10-14		.txt	text/plain	8124	415	48	noldeae, as well as caffeic acid, isoquercetin, and ER2.4 and ER2.7 fractions revealed significant inhibitory effects on Caspase-1 activities, and on IL-1β and IL-6 production. noldeae, as well as caffeic acid, isoquercetin, and ER2.4 and ER2.7 fractions revealed the highest inhibitory effects on Caspase-1 activities, and on IL-1β and IL-6 production. Therefore, we investigated the effect of our compounds and fractions of interest on inflammasome activation-induced cell death by measuring the release of lactate dehydrogenase (LDH) in the culture Concentrations of 20 µM YVAD and 20 µg/mL Dex were used as controls. Therefore, we investigated the effect of our compounds and fractions of interest on inflammasome activation-induced cell death by measuring the release of lactate dehydrogenase (LDH) in the culture supernatants. Before investigating the anti-inflammatory activity of different fractions, their effect on the cell viability (THP-1, monocytes and derived-macrophages, and RAW264.7) was screened as previously reported [21] .	./cache/cord-280807-0g1uo0rd.txt	./txt/cord-280807-0g1uo0rd.txt