key: cord-331140-5b0y1xzb
authors: Cardona Maya, Walter D.; Carvajal, Alejandro
title: SARS-CoV-2 and Prostatitis: dangerous relationship for male sexual and reproductive health
date: 2020-06-01
journal: Med Hypotheses
DOI: 10.1016/j.mehy.2020.109914
sha: 
doc_id: 331140
cord_uid: 5b0y1xzb

nan

. Recently, SARS-CoV-2 was detected in semen samples (5) . Therefore, it is not unreasonable to believe that the latest coronavirus could potentially be transmitted via semen (6) .

It was also reported that angiotensin converting enzyme 2 (ACE2) is a functional receptor that mediates the entry of SARS-CoV-1 (7) and 2 (8) , and this receptor is expressed in the prostate. Thus, virus binding to these ACE2 positive cells can potentially not only cause tissue alterations but also serve as a source of the virus secreted and actively pass to the ejaculate.

Thus, there is a significant group of patients with COVID-19 who are susceptible to suffering from prostatitis. Perhaps in the coming years, the real effect of SARS-CoV-2 on prostatitis cases will be evaluated and scope for researching factors that cause the clinical syndrome will be expanded. Further, it is possible that viral typing tests will be routinely carried out, among which the coronavirus will be mandatory.

The article has no funding source

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Epidemiology of prostatitis in Finnish men: a population-based cross-sectional study

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Male infertility: a public health issue caused by sexually transmitted pathogens

Orchitis: a complication of severe acute respiratory syndrome (SARS)

Clinical Characteristics and Results of Semen Tests Among Men With Coronavirus Disease

SARS-CoV-2 and the Testis: similarity to other viruses and routes of infection

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

A pneumonia outbreak associated with a new coronavirus of probable bat origin