id sid tid token lemma pos cord-338585-ep9r1n8t 1 1 key key JJ cord-338585-ep9r1n8t 1 2 : : : cord-338585-ep9r1n8t 1 3 cord-338585-ep9r1n8 cord-338585-ep9r1n8 NNP cord-338585-ep9r1n8t 1 4 t t NN cord-338585-ep9r1n8t 1 5 authors author NNS cord-338585-ep9r1n8t 1 6 : : : cord-338585-ep9r1n8t 1 7 Perrin Perrin NNP cord-338585-ep9r1n8t 1 8 , , , cord-338585-ep9r1n8t 1 9 David David NNP cord-338585-ep9r1n8t 1 10 M. M. NNP cord-338585-ep9r1n8t 1 11 title title NN cord-338585-ep9r1n8t 1 12 : : : cord-338585-ep9r1n8t 2 1 A a DT cord-338585-ep9r1n8t 2 2 hypothesis hypothesis NN cord-338585-ep9r1n8t 2 3 for for IN cord-338585-ep9r1n8t 2 4 examining examine VBG cord-338585-ep9r1n8t 2 5 dihydroxyacetone dihydroxyacetone NNP cord-338585-ep9r1n8t 2 6 , , , cord-338585-ep9r1n8t 2 7 the the DT cord-338585-ep9r1n8t 2 8 active active JJ cord-338585-ep9r1n8t 2 9 component component NN cord-338585-ep9r1n8t 2 10 in in IN cord-338585-ep9r1n8t 2 11 self self NN cord-338585-ep9r1n8t 2 12 - - HYPH cord-338585-ep9r1n8t 2 13 tanning tanning NN cord-338585-ep9r1n8t 2 14 products product NNS cord-338585-ep9r1n8t 2 15 , , , cord-338585-ep9r1n8t 2 16 as as IN cord-338585-ep9r1n8t 2 17 a a DT cord-338585-ep9r1n8t 2 18 topical topical JJ cord-338585-ep9r1n8t 2 19 prophylactic prophylactic NN cord-338585-ep9r1n8t 2 20 against against IN cord-338585-ep9r1n8t 2 21 SARS SARS NNP cord-338585-ep9r1n8t 2 22 - - HYPH cord-338585-ep9r1n8t 2 23 COV-2 COV-2 NNP cord-338585-ep9r1n8t 2 24 transmission transmission NN cord-338585-ep9r1n8t 2 25 date date NN cord-338585-ep9r1n8t 2 26 : : : cord-338585-ep9r1n8t 2 27 2020 2020 CD cord-338585-ep9r1n8t 2 28 - - HYPH cord-338585-ep9r1n8t 2 29 09 09 CD cord-338585-ep9r1n8t 2 30 - - SYM cord-338585-ep9r1n8t 2 31 16 16 CD cord-338585-ep9r1n8t 2 32 journal journal NN cord-338585-ep9r1n8t 2 33 : : : cord-338585-ep9r1n8t 3 1 Med Med NNP cord-338585-ep9r1n8t 3 2 Hypotheses Hypotheses NNP cord-338585-ep9r1n8t 3 3 DOI DOI NNP cord-338585-ep9r1n8t 3 4 : : : cord-338585-ep9r1n8t 3 5 10.1016 10.1016 CD cord-338585-ep9r1n8t 3 6 / / SYM cord-338585-ep9r1n8t 3 7 j.mehy.2020.110280 j.mehy.2020.110280 NN cord-338585-ep9r1n8t 3 8 sha sha NNP cord-338585-ep9r1n8t 3 9 : : : cord-338585-ep9r1n8t 3 10 f46fa8619c8d0b7f551fde2975950d5430393f18 f46fa8619c8d0b7f551fde2975950d5430393f18 NFP cord-338585-ep9r1n8t 3 11 doc_id doc_id CD cord-338585-ep9r1n8t 3 12 : : : cord-338585-ep9r1n8t 3 13 338585 338585 CD cord-338585-ep9r1n8t 3 14 cord_uid cord_uid NN cord-338585-ep9r1n8t 3 15 : : : cord-338585-ep9r1n8t 4 1 ep9r1n8 ep9r1n8 NNP cord-338585-ep9r1n8t 5 1 t t NNP cord-338585-ep9r1n8t 6 1 This this DT cord-338585-ep9r1n8t 6 2 hypothesis hypothesis NN cord-338585-ep9r1n8t 6 3 raises raise VBZ cord-338585-ep9r1n8t 6 4 the the DT cord-338585-ep9r1n8t 6 5 interesting interesting JJ cord-338585-ep9r1n8t 6 6 prospect prospect NN cord-338585-ep9r1n8t 6 7 that that IN cord-338585-ep9r1n8t 6 8 dihydroxyacetone dihydroxyacetone NNP cord-338585-ep9r1n8t 6 9 ( ( -LRB- cord-338585-ep9r1n8t 6 10 DHA DHA NNP cord-338585-ep9r1n8t 6 11 ) ) -RRB- cord-338585-ep9r1n8t 6 12 , , , cord-338585-ep9r1n8t 6 13 the the DT cord-338585-ep9r1n8t 6 14 key key JJ cord-338585-ep9r1n8t 6 15 ingredient ingredient NN cord-338585-ep9r1n8t 6 16 in in IN cord-338585-ep9r1n8t 6 17 self self NN cord-338585-ep9r1n8t 6 18 - - HYPH cord-338585-ep9r1n8t 6 19 tanning tanning NN cord-338585-ep9r1n8t 6 20 creams cream NNS cord-338585-ep9r1n8t 6 21 , , , cord-338585-ep9r1n8t 6 22 when when WRB cord-338585-ep9r1n8t 6 23 applied apply VBN cord-338585-ep9r1n8t 6 24 daily daily RB cord-338585-ep9r1n8t 6 25 to to IN cord-338585-ep9r1n8t 6 26 the the DT cord-338585-ep9r1n8t 6 27 face face NN cord-338585-ep9r1n8t 6 28 and and CC cord-338585-ep9r1n8t 6 29 hands hand NNS cord-338585-ep9r1n8t 6 30 may may MD cord-338585-ep9r1n8t 6 31 have have VB cord-338585-ep9r1n8t 6 32 prophylactic prophylactic JJ cord-338585-ep9r1n8t 6 33 action action NN cord-338585-ep9r1n8t 6 34 against against IN cord-338585-ep9r1n8t 6 35 SARS SARS NNP cord-338585-ep9r1n8t 6 36 - - HYPH cord-338585-ep9r1n8t 6 37 COV-2 COV-2 NNP cord-338585-ep9r1n8t 6 38 transmission transmission NN cord-338585-ep9r1n8t 6 39 and and CC cord-338585-ep9r1n8t 6 40 infection infection NN cord-338585-ep9r1n8t 6 41 . . . cord-338585-ep9r1n8t 7 1 The the DT cord-338585-ep9r1n8t 7 2 scientific scientific JJ cord-338585-ep9r1n8t 7 3 and and CC cord-338585-ep9r1n8t 7 4 mechanistic mechanistic JJ cord-338585-ep9r1n8t 7 5 basis basis NN cord-338585-ep9r1n8t 7 6 for for IN cord-338585-ep9r1n8t 7 7 this this DT cord-338585-ep9r1n8t 7 8 hypothesis hypothesis NN cord-338585-ep9r1n8t 7 9 is be VBZ cord-338585-ep9r1n8t 7 10 elaborated elaborate VBN cord-338585-ep9r1n8t 7 11 based base VBN cord-338585-ep9r1n8t 7 12 on on IN cord-338585-ep9r1n8t 7 13 our -PRON- PRP$ cord-338585-ep9r1n8t 7 14 understanding understanding NN cord-338585-ep9r1n8t 7 15 of of IN cord-338585-ep9r1n8t 7 16 the the DT cord-338585-ep9r1n8t 7 17 chemical chemical JJ cord-338585-ep9r1n8t 7 18 reactivity reactivity NN cord-338585-ep9r1n8t 7 19 of of IN cord-338585-ep9r1n8t 7 20 DHA DHA NNP cord-338585-ep9r1n8t 7 21 with with IN cord-338585-ep9r1n8t 7 22 proteins protein NNS cord-338585-ep9r1n8t 7 23 to to TO cord-338585-ep9r1n8t 7 24 afford afford VB cord-338585-ep9r1n8t 7 25 advanced advanced JJ cord-338585-ep9r1n8t 7 26 glycation glycation NN cord-338585-ep9r1n8t 7 27 products product NNS cord-338585-ep9r1n8t 7 28 . . . cord-338585-ep9r1n8t 8 1 This this DT cord-338585-ep9r1n8t 8 2 piece piece NN cord-338585-ep9r1n8t 8 3 ends end VBZ cord-338585-ep9r1n8t 8 4 with with IN cord-338585-ep9r1n8t 8 5 a a DT cord-338585-ep9r1n8t 8 6 proposal proposal NN cord-338585-ep9r1n8t 8 7 for for IN cord-338585-ep9r1n8t 8 8 doing do VBG cord-338585-ep9r1n8t 8 9 key key JJ cord-338585-ep9r1n8t 8 10 experiments experiment NNS cord-338585-ep9r1n8t 8 11 that that WDT cord-338585-ep9r1n8t 8 12 can can MD cord-338585-ep9r1n8t 8 13 be be VB cord-338585-ep9r1n8t 8 14 run run VBN cord-338585-ep9r1n8t 8 15 to to TO cord-338585-ep9r1n8t 8 16 test test VB cord-338585-ep9r1n8t 8 17 this this DT cord-338585-ep9r1n8t 8 18 hypothesis hypothesis NN cord-338585-ep9r1n8t 8 19 . . . cord-338585-ep9r1n8t 9 1 As as IN cord-338585-ep9r1n8t 9 2 more more JJR cord-338585-ep9r1n8t 9 3 than than IN cord-338585-ep9r1n8t 9 4 20 20 CD cord-338585-ep9r1n8t 9 5 million million CD cord-338585-ep9r1n8t 9 6 people people NNS cord-338585-ep9r1n8t 9 7 have have VBP cord-338585-ep9r1n8t 9 8 been be VBN cord-338585-ep9r1n8t 9 9 infected infect VBN cord-338585-ep9r1n8t 9 10 with with IN cord-338585-ep9r1n8t 9 11 this this DT cord-338585-ep9r1n8t 9 12 disease disease NN cord-338585-ep9r1n8t 9 13 world world NN cord-338585-ep9r1n8t 9 14 - - HYPH cord-338585-ep9r1n8t 9 15 wide wide RB cord-338585-ep9r1n8t 9 16 , , , cord-338585-ep9r1n8t 9 17 a a DT cord-338585-ep9r1n8t 9 18 safe safe JJ cord-338585-ep9r1n8t 9 19 method method NN cord-338585-ep9r1n8t 9 20 for for IN cord-338585-ep9r1n8t 9 21 stopping stop VBG cord-338585-ep9r1n8t 9 22 spread spread NN cord-338585-ep9r1n8t 9 23 is be VBZ cord-338585-ep9r1n8t 9 24 worthy worthy JJ cord-338585-ep9r1n8t 9 25 of of IN cord-338585-ep9r1n8t 9 26 consideration consideration NN cord-338585-ep9r1n8t 9 27 . . . cord-338585-ep9r1n8t 10 1 Publication publication NN cord-338585-ep9r1n8t 10 2 of of IN cord-338585-ep9r1n8t 10 3 this this DT cord-338585-ep9r1n8t 10 4 hypothesis hypothesis NN cord-338585-ep9r1n8t 10 5 would would MD cord-338585-ep9r1n8t 10 6 enable enable VB cord-338585-ep9r1n8t 10 7 the the DT cord-338585-ep9r1n8t 10 8 scientific scientific JJ cord-338585-ep9r1n8t 10 9 community community NN cord-338585-ep9r1n8t 10 10 at at IN cord-338585-ep9r1n8t 10 11 large large JJ cord-338585-ep9r1n8t 10 12 to to TO cord-338585-ep9r1n8t 10 13 test test VB cord-338585-ep9r1n8t 10 14 this this DT cord-338585-ep9r1n8t 10 15 in in IN cord-338585-ep9r1n8t 10 16 a a DT cord-338585-ep9r1n8t 10 17 clinically clinically RB cord-338585-ep9r1n8t 10 18 meaningful meaningful JJ cord-338585-ep9r1n8t 10 19 setting setting NN cord-338585-ep9r1n8t 10 20 to to TO cord-338585-ep9r1n8t 10 21 address address VB cord-338585-ep9r1n8t 10 22 the the DT cord-338585-ep9r1n8t 10 23 potential potential NN cord-338585-ep9r1n8t 10 24 for for IN cord-338585-ep9r1n8t 10 25 DHA DHA NNP cord-338585-ep9r1n8t 10 26 - - HYPH cord-338585-ep9r1n8t 10 27 based base VBN cord-338585-ep9r1n8t 10 28 prophylaxis prophylaxis NN cord-338585-ep9r1n8t 10 29 . . . cord-338585-ep9r1n8t 11 1 Given give VBN cord-338585-ep9r1n8t 11 2 the the DT cord-338585-ep9r1n8t 11 3 calamity calamity NN cord-338585-ep9r1n8t 11 4 of of IN cord-338585-ep9r1n8t 11 5 this this DT cord-338585-ep9r1n8t 11 6 crisis crisis NN cord-338585-ep9r1n8t 11 7 , , , cord-338585-ep9r1n8t 11 8 it -PRON- PRP cord-338585-ep9r1n8t 11 9 is be VBZ cord-338585-ep9r1n8t 11 10 anticipated anticipate VBN cord-338585-ep9r1n8t 11 11 that that IN cord-338585-ep9r1n8t 11 12 the the DT cord-338585-ep9r1n8t 11 13 publication publication NN cord-338585-ep9r1n8t 11 14 of of IN cord-338585-ep9r1n8t 11 15 this this DT cord-338585-ep9r1n8t 11 16 hypothesis hypothesis NN cord-338585-ep9r1n8t 11 17 , , , cord-338585-ep9r1n8t 11 18 which which WDT cord-338585-ep9r1n8t 11 19 is be VBZ cord-338585-ep9r1n8t 11 20 supported support VBN cord-338585-ep9r1n8t 11 21 by by IN cord-338585-ep9r1n8t 11 22 key key JJ cord-338585-ep9r1n8t 11 23 studies study NNS cord-338585-ep9r1n8t 11 24 on on IN cord-338585-ep9r1n8t 11 25 protein protein NN cord-338585-ep9r1n8t 11 26 and and CC cord-338585-ep9r1n8t 11 27 nucleoside nucleoside JJ cord-338585-ep9r1n8t 11 28 glycation glycation NN cord-338585-ep9r1n8t 11 29 , , , cord-338585-ep9r1n8t 11 30 can can MD cord-338585-ep9r1n8t 11 31 be be VB cord-338585-ep9r1n8t 11 32 disseminated disseminate VBN cord-338585-ep9r1n8t 11 33 to to IN cord-338585-ep9r1n8t 11 34 as as RB cord-338585-ep9r1n8t 11 35 many many JJ cord-338585-ep9r1n8t 11 36 researchers researcher NNS cord-338585-ep9r1n8t 11 37 as as IN cord-338585-ep9r1n8t 11 38 possible possible JJ cord-338585-ep9r1n8t 11 39 . . . cord-338585-ep9r1n8t 12 1 David David NNP cord-338585-ep9r1n8t 12 2 M. M. NNP cord-338585-ep9r1n8t 12 3 Perrin Perrin NNP cord-338585-ep9r1n8t 12 4 , , , cord-338585-ep9r1n8t 12 5 Ph.D. ph.d. NN cord-338585-ep9r1n8t 12 6 , , , cord-338585-ep9r1n8t 12 7 Chemistry Chemistry NNP cord-338585-ep9r1n8t 12 8 Department Department NNP cord-338585-ep9r1n8t 12 9 , , , cord-338585-ep9r1n8t 12 10 2036 2036 CD cord-338585-ep9r1n8t 12 11 Main Main NNP cord-338585-ep9r1n8t 12 12 Mall Mall NNP cord-338585-ep9r1n8t 12 13 -UBC -ubc NN cord-338585-ep9r1n8t 12 14 , , , cord-338585-ep9r1n8t 12 15 Vancouver Vancouver NNP cord-338585-ep9r1n8t 12 16 , , , cord-338585-ep9r1n8t 12 17 BC BC NNP cord-338585-ep9r1n8t 12 18 , , , cord-338585-ep9r1n8t 12 19 V6T1Z1 v6t1z1 NN cord-338585-ep9r1n8t 12 20 , , , cord-338585-ep9r1n8t 12 21 dperrin@chem.ubc.ca dperrin@chem.ubc.ca NNP cord-338585-ep9r1n8t 13 1 As as IN cord-338585-ep9r1n8t 13 2 SARS SARS NNP cord-338585-ep9r1n8t 13 3 - - HYPH cord-338585-ep9r1n8t 13 4 COV-2 COV-2 NNP cord-338585-ep9r1n8t 13 5 ravages ravage VBZ cord-338585-ep9r1n8t 13 6 the the DT cord-338585-ep9r1n8t 13 7 world world NN cord-338585-ep9r1n8t 13 8 , , , cord-338585-ep9r1n8t 13 9 over over IN cord-338585-ep9r1n8t 13 10 28 28 CD cord-338585-ep9r1n8t 13 11 million million CD cord-338585-ep9r1n8t 13 12 people people NNS cord-338585-ep9r1n8t 13 13 and and CC cord-338585-ep9r1n8t 13 14 counting counting NN cord-338585-ep9r1n8t 13 15 have have VBP cord-338585-ep9r1n8t 13 16 now now RB cord-338585-ep9r1n8t 13 17 tested test VBN cord-338585-ep9r1n8t 13 18 positive positive JJ cord-338585-ep9r1n8t 13 19 for for IN cord-338585-ep9r1n8t 13 20 the the DT cord-338585-ep9r1n8t 13 21 disease disease NN cord-338585-ep9r1n8t 13 22 while while IN cord-338585-ep9r1n8t 13 23 mortality mortality NN cord-338585-ep9r1n8t 13 24 rates rate NNS cord-338585-ep9r1n8t 13 25 are be VBP cord-338585-ep9r1n8t 13 26 of of IN cord-338585-ep9r1n8t 13 27 great great JJ cord-338585-ep9r1n8t 13 28 concern concern NN cord-338585-ep9r1n8t 13 29 . . . cord-338585-ep9r1n8t 14 1 The the DT cord-338585-ep9r1n8t 14 2 virus virus NN cord-338585-ep9r1n8t 14 3 is be VBZ cord-338585-ep9r1n8t 14 4 transmitted transmit VBN cord-338585-ep9r1n8t 14 5 by by IN cord-338585-ep9r1n8t 14 6 : : : cord-338585-ep9r1n8t 14 7 1 1 LS cord-338585-ep9r1n8t 14 8 ) ) -RRB- cord-338585-ep9r1n8t 14 9 respiration respiration NN cord-338585-ep9r1n8t 14 10 of of IN cord-338585-ep9r1n8t 14 11 aerosolized aerosolized JJ cord-338585-ep9r1n8t 14 12 droplets droplet NNS cord-338585-ep9r1n8t 14 13 containing contain VBG cord-338585-ep9r1n8t 14 14 the the DT cord-338585-ep9r1n8t 14 15 virus virus NN cord-338585-ep9r1n8t 14 16 ; ; : cord-338585-ep9r1n8t 14 17 2 2 LS cord-338585-ep9r1n8t 14 18 ) ) -RRB- cord-338585-ep9r1n8t 14 19 contaminated contaminate VBN cord-338585-ep9r1n8t 14 20 hands hand NNS cord-338585-ep9r1n8t 14 21 passing pass VBG cord-338585-ep9r1n8t 14 22 the the DT cord-338585-ep9r1n8t 14 23 virus virus NN cord-338585-ep9r1n8t 14 24 directly directly RB cord-338585-ep9r1n8t 14 25 into into IN cord-338585-ep9r1n8t 14 26 the the DT cord-338585-ep9r1n8t 14 27 eyes eye NNS cord-338585-ep9r1n8t 14 28 or or CC cord-338585-ep9r1n8t 14 29 mouth mouth NN cord-338585-ep9r1n8t 14 30 ; ; : cord-338585-ep9r1n8t 14 31 and and CC cord-338585-ep9r1n8t 14 32 3 3 LS cord-338585-ep9r1n8t 14 33 ) ) -RRB- cord-338585-ep9r1n8t 14 34 transferring transfer VBG cord-338585-ep9r1n8t 14 35 the the DT cord-338585-ep9r1n8t 14 36 virus virus NN cord-338585-ep9r1n8t 14 37 that that WDT cord-338585-ep9r1n8t 14 38 lands land VBZ cord-338585-ep9r1n8t 14 39 on on IN cord-338585-ep9r1n8t 14 40 the the DT cord-338585-ep9r1n8t 14 41 face face NN cord-338585-ep9r1n8t 14 42 to to IN cord-338585-ep9r1n8t 14 43 the the DT cord-338585-ep9r1n8t 14 44 eyes eye NNS cord-338585-ep9r1n8t 14 45 , , , cord-338585-ep9r1n8t 14 46 nose nose NN cord-338585-ep9r1n8t 14 47 , , , cord-338585-ep9r1n8t 14 48 or or CC cord-338585-ep9r1n8t 14 49 mouth mouth NN cord-338585-ep9r1n8t 14 50 by by IN cord-338585-ep9r1n8t 14 51 face face NN cord-338585-ep9r1n8t 14 52 touching touching JJ cord-338585-ep9r1n8t 14 53 . . . cord-338585-ep9r1n8t 15 1 As as IN cord-338585-ep9r1n8t 15 2 the the DT cord-338585-ep9r1n8t 15 3 hands hand NNS cord-338585-ep9r1n8t 15 4 and and CC cord-338585-ep9r1n8t 15 5 face face NN cord-338585-ep9r1n8t 15 6 is be VBZ cord-338585-ep9r1n8t 15 7 known know VBN cord-338585-ep9r1n8t 15 8 to to TO cord-338585-ep9r1n8t 15 9 be be VB cord-338585-ep9r1n8t 15 10 a a DT cord-338585-ep9r1n8t 15 11 major major JJ cord-338585-ep9r1n8t 15 12 point point NN cord-338585-ep9r1n8t 15 13 of of IN cord-338585-ep9r1n8t 15 14 transmission transmission NN cord-338585-ep9r1n8t 15 15 , , , cord-338585-ep9r1n8t 15 16 there there EX cord-338585-ep9r1n8t 15 17 has have VBZ cord-338585-ep9r1n8t 15 18 been be VBN cord-338585-ep9r1n8t 15 19 an an DT cord-338585-ep9r1n8t 15 20 urgent urgent JJ cord-338585-ep9r1n8t 15 21 need need NN cord-338585-ep9r1n8t 15 22 to to TO cord-338585-ep9r1n8t 15 23 identify identify VB cord-338585-ep9r1n8t 15 24 safe safe JJ cord-338585-ep9r1n8t 15 25 chemicals chemical NNS cord-338585-ep9r1n8t 15 26 that that WDT cord-338585-ep9r1n8t 15 27 could could MD cord-338585-ep9r1n8t 15 28 be be VB cord-338585-ep9r1n8t 15 29 applied apply VBN cord-338585-ep9r1n8t 15 30 topically topically RB cord-338585-ep9r1n8t 15 31 to to IN cord-338585-ep9r1n8t 15 32 the the DT cord-338585-ep9r1n8t 15 33 skin skin NN cord-338585-ep9r1n8t 15 34 to to TO cord-338585-ep9r1n8t 15 35 reduce reduce VB cord-338585-ep9r1n8t 15 36 the the DT cord-338585-ep9r1n8t 15 37 risk risk NN cord-338585-ep9r1n8t 15 38 of of IN cord-338585-ep9r1n8t 15 39 facial facial JJ cord-338585-ep9r1n8t 15 40 transmission transmission NN cord-338585-ep9r1n8t 15 41 . . . cord-338585-ep9r1n8t 16 1 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 16 2 ( ( -LRB- cord-338585-ep9r1n8t 16 3 DHA DHA NNP cord-338585-ep9r1n8t 16 4 , , , cord-338585-ep9r1n8t 16 5 Figure figure NN cord-338585-ep9r1n8t 16 6 1 1 CD cord-338585-ep9r1n8t 16 7 ) ) -RRB- cord-338585-ep9r1n8t 16 8 , , , cord-338585-ep9r1n8t 16 9 the the DT cord-338585-ep9r1n8t 16 10 active active JJ cord-338585-ep9r1n8t 16 11 ingredient ingredient NN cord-338585-ep9r1n8t 16 12 in in IN cord-338585-ep9r1n8t 16 13 sunless sunless JJ cord-338585-ep9r1n8t 16 14 tanning tanning NN cord-338585-ep9r1n8t 16 15 creams cream NNS cord-338585-ep9r1n8t 16 16 , , , cord-338585-ep9r1n8t 16 17 which which WDT cord-338585-ep9r1n8t 16 18 gives give VBZ cord-338585-ep9r1n8t 16 19 a a DT cord-338585-ep9r1n8t 16 20 characteristic characteristic JJ cord-338585-ep9r1n8t 16 21 orange orange NN cord-338585-ep9r1n8t 16 22 color color NN cord-338585-ep9r1n8t 16 23 , , , cord-338585-ep9r1n8t 16 24 may may MD cord-338585-ep9r1n8t 16 25 be be VB cord-338585-ep9r1n8t 16 26 of of IN cord-338585-ep9r1n8t 16 27 significant significant JJ cord-338585-ep9r1n8t 16 28 and and CC cord-338585-ep9r1n8t 16 29 immediate immediate JJ cord-338585-ep9r1n8t 16 30 interest interest NN cord-338585-ep9r1n8t 16 31 . . . cord-338585-ep9r1n8t 17 1 DHA DHA NNP cord-338585-ep9r1n8t 17 2 reacts react VBZ cord-338585-ep9r1n8t 17 3 chemically chemically RB cord-338585-ep9r1n8t 17 4 with with IN cord-338585-ep9r1n8t 17 5 proteins protein NNS cord-338585-ep9r1n8t 17 6 to to TO cord-338585-ep9r1n8t 17 7 form form VB cord-338585-ep9r1n8t 17 8 glycation glycation NN cord-338585-ep9r1n8t 17 9 products product NNS cord-338585-ep9r1n8t 17 10 and and CC cord-338585-ep9r1n8t 17 11 thus thus RB cord-338585-ep9r1n8t 17 12 would would MD cord-338585-ep9r1n8t 17 13 be be VB cord-338585-ep9r1n8t 17 14 expected expect VBN cord-338585-ep9r1n8t 17 15 to to TO cord-338585-ep9r1n8t 17 16 react react VB cord-338585-ep9r1n8t 17 17 analogously analogously RB cord-338585-ep9r1n8t 17 18 with with IN cord-338585-ep9r1n8t 17 19 viral viral JJ cord-338585-ep9r1n8t 17 20 components component NNS cord-338585-ep9r1n8t 17 21 such such JJ cord-338585-ep9r1n8t 17 22 that that IN cord-338585-ep9r1n8t 17 23 it -PRON- PRP cord-338585-ep9r1n8t 17 24 might may MD cord-338585-ep9r1n8t 17 25 provide provide VB cord-338585-ep9r1n8t 17 26 prophylactic prophylactic JJ cord-338585-ep9r1n8t 17 27 action action NN cord-338585-ep9r1n8t 17 28 against against IN cord-338585-ep9r1n8t 17 29 anti anti JJ cord-338585-ep9r1n8t 17 30 - - JJ cord-338585-ep9r1n8t 17 31 SARS SARS NNP cord-338585-ep9r1n8t 17 32 - - HYPH cord-338585-ep9r1n8t 17 33 CoV-2 CoV-2 NNP cord-338585-ep9r1n8t 17 34 . . . cord-338585-ep9r1n8t 18 1 If if IN cord-338585-ep9r1n8t 18 2 so so RB cord-338585-ep9r1n8t 18 3 , , , cord-338585-ep9r1n8t 18 4 this this DT cord-338585-ep9r1n8t 18 5 cheap cheap JJ cord-338585-ep9r1n8t 18 6 , , , cord-338585-ep9r1n8t 18 7 nontoxic nontoxic JJ cord-338585-ep9r1n8t 18 8 molecule molecule NN cord-338585-ep9r1n8t 18 9 may may MD cord-338585-ep9r1n8t 18 10 be be VB cord-338585-ep9r1n8t 18 11 worthy worthy JJ cord-338585-ep9r1n8t 18 12 of of IN cord-338585-ep9r1n8t 18 13 consideration consideration NN cord-338585-ep9r1n8t 18 14 for for IN cord-338585-ep9r1n8t 18 15 limiting limit VBG cord-338585-ep9r1n8t 18 16 facial facial JJ cord-338585-ep9r1n8t 18 17 transmission transmission NN cord-338585-ep9r1n8t 18 18 , , , cord-338585-ep9r1n8t 18 19 notwithstanding notwithstanding IN cord-338585-ep9r1n8t 18 20 the the DT cord-338585-ep9r1n8t 18 21 cosmetic cosmetic JJ cord-338585-ep9r1n8t 18 22 value value NN cord-338585-ep9r1n8t 18 23 . . . cord-338585-ep9r1n8t 19 1 Here here RB cord-338585-ep9r1n8t 19 2 , , , cord-338585-ep9r1n8t 19 3 I -PRON- PRP cord-338585-ep9r1n8t 19 4 will will MD cord-338585-ep9r1n8t 19 5 review review VB cord-338585-ep9r1n8t 19 6 the the DT cord-338585-ep9r1n8t 19 7 paraclinical paraclinical JJ cord-338585-ep9r1n8t 19 8 history history NN cord-338585-ep9r1n8t 19 9 of of IN cord-338585-ep9r1n8t 19 10 DHA DHA NNP cord-338585-ep9r1n8t 19 11 and and CC cord-338585-ep9r1n8t 19 12 provide provide VB cord-338585-ep9r1n8t 19 13 sound sound JJ cord-338585-ep9r1n8t 19 14 biochemical biochemical JJ cord-338585-ep9r1n8t 19 15 evidence evidence NN cord-338585-ep9r1n8t 19 16 of of IN cord-338585-ep9r1n8t 19 17 its -PRON- PRP$ cord-338585-ep9r1n8t 19 18 chemical chemical NN cord-338585-ep9r1n8t 19 19 reactivity reactivity NN cord-338585-ep9r1n8t 19 20 towards towards IN cord-338585-ep9r1n8t 19 21 either either DT cord-338585-ep9r1n8t 19 22 protein protein NN cord-338585-ep9r1n8t 20 1 e.g. e.g. RB cord-338585-ep9r1n8t 20 2 the the DT cord-338585-ep9r1n8t 20 3 viral viral JJ cord-338585-ep9r1n8t 20 4 coat coat NN cord-338585-ep9r1n8t 20 5 and and CC cord-338585-ep9r1n8t 20 6 nucleocapsid nucleocapsid NN cord-338585-ep9r1n8t 20 7 proteins protein NNS cord-338585-ep9r1n8t 20 8 , , , cord-338585-ep9r1n8t 20 9 or or CC cord-338585-ep9r1n8t 20 10 RNA RNA NNP cord-338585-ep9r1n8t 20 11 e.g. e.g. IN cord-338585-ep9r1n8t 20 12 the the DT cord-338585-ep9r1n8t 20 13 viral viral JJ cord-338585-ep9r1n8t 20 14 genome genome NN cord-338585-ep9r1n8t 20 15 to to TO cord-338585-ep9r1n8t 20 16 support support VB cord-338585-ep9r1n8t 20 17 measured measure VBN cord-338585-ep9r1n8t 20 18 exploration exploration NN cord-338585-ep9r1n8t 20 19 of of IN cord-338585-ep9r1n8t 20 20 its -PRON- PRP$ cord-338585-ep9r1n8t 20 21 topical topical JJ cord-338585-ep9r1n8t 20 22 use use NN cord-338585-ep9r1n8t 20 23 to to TO cord-338585-ep9r1n8t 20 24 prevent prevent VB cord-338585-ep9r1n8t 20 25 facial facial JJ cord-338585-ep9r1n8t 20 26 transmission transmission NN cord-338585-ep9r1n8t 20 27 . . . cord-338585-ep9r1n8t 21 1 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 21 2 is be VBZ cord-338585-ep9r1n8t 21 3 the the DT cord-338585-ep9r1n8t 21 4 simplest simple JJS cord-338585-ep9r1n8t 21 5 keto keto JJ cord-338585-ep9r1n8t 21 6 - - HYPH cord-338585-ep9r1n8t 21 7 sugar sugar NNP cord-338585-ep9r1n8t 21 8 and and CC cord-338585-ep9r1n8t 21 9 its -PRON- PRP$ cord-338585-ep9r1n8t 21 10 monophosphate monophosphate NN cord-338585-ep9r1n8t 21 11 ester ester NN cord-338585-ep9r1n8t 21 12 ( ( -LRB- cord-338585-ep9r1n8t 21 13 dihydroxyacetone dihydroxyacetone NN cord-338585-ep9r1n8t 21 14 phosphate phosphate NN cord-338585-ep9r1n8t 21 15 -DHAP -DHAP . cord-338585-ep9r1n8t 21 16 ) ) -RRB- cord-338585-ep9r1n8t 21 17 is be VBZ cord-338585-ep9r1n8t 21 18 an an DT cord-338585-ep9r1n8t 21 19 intermediate intermediate JJ cord-338585-ep9r1n8t 21 20 in in IN cord-338585-ep9r1n8t 21 21 glycolysis glycolysis NN cord-338585-ep9r1n8t 21 22 . . . cord-338585-ep9r1n8t 22 1 Nearly nearly RB cord-338585-ep9r1n8t 22 2 a a DT cord-338585-ep9r1n8t 22 3 century century NN cord-338585-ep9r1n8t 22 4 ago ago RB cord-338585-ep9r1n8t 22 5 , , , cord-338585-ep9r1n8t 22 6 DHA DHA NNP cord-338585-ep9r1n8t 22 7 was be VBD cord-338585-ep9r1n8t 22 8 first first RB cord-338585-ep9r1n8t 22 9 administered administer VBN cord-338585-ep9r1n8t 22 10 orally orally RB cord-338585-ep9r1n8t 22 11 in in IN cord-338585-ep9r1n8t 22 12 a a DT cord-338585-ep9r1n8t 22 13 failed fail VBN cord-338585-ep9r1n8t 22 14 attempt attempt NN cord-338585-ep9r1n8t 22 15 to to TO cord-338585-ep9r1n8t 22 16 treat treat VB cord-338585-ep9r1n8t 22 17 type type NN cord-338585-ep9r1n8t 22 18 - - : cord-338585-ep9r1n8t 22 19 I i NN cord-338585-ep9r1n8t 22 20 diabetic diabetic JJ cord-338585-ep9r1n8t 22 21 children child NNS cord-338585-ep9r1n8t 22 22 with with IN cord-338585-ep9r1n8t 22 23 a a DT cord-338585-ep9r1n8t 22 24 " " `` cord-338585-ep9r1n8t 22 25 keto keto NNP cord-338585-ep9r1n8t 22 26 " " '' cord-338585-ep9r1n8t 22 27 diet(1 diet(1 NN cord-338585-ep9r1n8t 22 28 , , , cord-338585-ep9r1n8t 22 29 2 2 CD cord-338585-ep9r1n8t 22 30 ) ) -RRB- cord-338585-ep9r1n8t 22 31 designed design VBN cord-338585-ep9r1n8t 22 32 to to TO cord-338585-ep9r1n8t 22 33 bypass bypass VB cord-338585-ep9r1n8t 22 34 glycolysis glycolysis NN cord-338585-ep9r1n8t 22 35 . . . cord-338585-ep9r1n8t 23 1 While while IN cord-338585-ep9r1n8t 23 2 ineffective ineffective JJ cord-338585-ep9r1n8t 23 3 for for IN cord-338585-ep9r1n8t 23 4 treating treat VBG cord-338585-ep9r1n8t 23 5 diabetes diabetes NN cord-338585-ep9r1n8t 23 6 , , , cord-338585-ep9r1n8t 23 7 DHA DHA NNP cord-338585-ep9r1n8t 23 8 was be VBD cord-338585-ep9r1n8t 23 9 found find VBN cord-338585-ep9r1n8t 23 10 to to TO cord-338585-ep9r1n8t 23 11 be be VB cord-338585-ep9r1n8t 23 12 nontoxic nontoxic JJ cord-338585-ep9r1n8t 23 13 . . . cord-338585-ep9r1n8t 24 1 Nevertheless nevertheless RB cord-338585-ep9r1n8t 24 2 , , , cord-338585-ep9r1n8t 24 3 this this DT cord-338585-ep9r1n8t 24 4 treatment treatment NN cord-338585-ep9r1n8t 24 5 resulted result VBD cord-338585-ep9r1n8t 24 6 in in IN cord-338585-ep9r1n8t 24 7 apparent apparent JJ cord-338585-ep9r1n8t 24 8 superficial superficial JJ cord-338585-ep9r1n8t 24 9 discoloration discoloration NN cord-338585-ep9r1n8t 24 10 in in IN cord-338585-ep9r1n8t 24 11 the the DT cord-338585-ep9r1n8t 24 12 gums gum NNS cord-338585-ep9r1n8t 24 13 and and CC cord-338585-ep9r1n8t 24 14 mouth(3 mouth(3 NNS cord-338585-ep9r1n8t 24 15 ) ) -RRB- cord-338585-ep9r1n8t 24 16 while while IN cord-338585-ep9r1n8t 24 17 regurgitation regurgitation NN cord-338585-ep9r1n8t 24 18 of of IN cord-338585-ep9r1n8t 24 19 DHA DHA NNP cord-338585-ep9r1n8t 24 20 on on IN cord-338585-ep9r1n8t 24 21 the the DT cord-338585-ep9r1n8t 24 22 skin skin NN cord-338585-ep9r1n8t 24 23 resulted result VBD cord-338585-ep9r1n8t 24 24 in in IN cord-338585-ep9r1n8t 24 25 notable notable JJ cord-338585-ep9r1n8t 24 26 discoloration discoloration NN cord-338585-ep9r1n8t 24 27 that that WDT cord-338585-ep9r1n8t 24 28 led lead VBD cord-338585-ep9r1n8t 24 29 to to IN cord-338585-ep9r1n8t 24 30 the the DT cord-338585-ep9r1n8t 24 31 serendipitous serendipitous JJ cord-338585-ep9r1n8t 24 32 discovery discovery NN cord-338585-ep9r1n8t 24 33 that that IN cord-338585-ep9r1n8t 24 34 DHA DHA NNP cord-338585-ep9r1n8t 24 35 could could MD cord-338585-ep9r1n8t 24 36 be be VB cord-338585-ep9r1n8t 24 37 used use VBN cord-338585-ep9r1n8t 24 38 for for IN cord-338585-ep9r1n8t 24 39 sunless sunless JJ cord-338585-ep9r1n8t 24 40 tanning tanning NN cord-338585-ep9r1n8t 24 41 . . . cord-338585-ep9r1n8t 25 1 Subsequently subsequently RB cord-338585-ep9r1n8t 25 2 , , , cord-338585-ep9r1n8t 25 3 DHA DHA NNP cord-338585-ep9r1n8t 25 4 was be VBD cord-338585-ep9r1n8t 25 5 investigated investigate VBN cord-338585-ep9r1n8t 25 6 for for IN cord-338585-ep9r1n8t 25 7 topical topical JJ cord-338585-ep9r1n8t 25 8 applications application NNS cord-338585-ep9r1n8t 25 9 to to TO cord-338585-ep9r1n8t 25 10 treat treat VB cord-338585-ep9r1n8t 25 11 vitiligo(4 vitiligo(4 RP cord-338585-ep9r1n8t 25 12 ) ) -RRB- cord-338585-ep9r1n8t 25 13 . . . cord-338585-ep9r1n8t 26 1 Considered consider VBN cord-338585-ep9r1n8t 26 2 to to TO cord-338585-ep9r1n8t 26 3 be be VB cord-338585-ep9r1n8t 26 4 safe safe JJ cord-338585-ep9r1n8t 26 5 , , , cord-338585-ep9r1n8t 26 6 DHA DHA NNP cord-338585-ep9r1n8t 26 7 is be VBZ cord-338585-ep9r1n8t 26 8 now now RB cord-338585-ep9r1n8t 26 9 used use VBN cord-338585-ep9r1n8t 26 10 as as IN cord-338585-ep9r1n8t 26 11 the the DT cord-338585-ep9r1n8t 26 12 key key JJ cord-338585-ep9r1n8t 26 13 ingredient ingredient NN cord-338585-ep9r1n8t 26 14 in in IN cord-338585-ep9r1n8t 26 15 sunless sunless JJ cord-338585-ep9r1n8t 26 16 tanning tanning NN cord-338585-ep9r1n8t 26 17 products product NNS cord-338585-ep9r1n8t 26 18 that that WDT cord-338585-ep9r1n8t 26 19 are be VBP cord-338585-ep9r1n8t 26 20 widely widely RB cord-338585-ep9r1n8t 26 21 available available JJ cord-338585-ep9r1n8t 26 22 without without IN cord-338585-ep9r1n8t 26 23 prescription(5 prescription(5 NNP cord-338585-ep9r1n8t 26 24 , , , cord-338585-ep9r1n8t 26 25 ) ) -RRB- cord-338585-ep9r1n8t 26 26 . . . cord-338585-ep9r1n8t 27 1 While while IN cord-338585-ep9r1n8t 27 2 such such JJ cord-338585-ep9r1n8t 27 3 products product NNS cord-338585-ep9r1n8t 27 4 may may MD cord-338585-ep9r1n8t 27 5 be be VB cord-338585-ep9r1n8t 27 6 used use VBN cord-338585-ep9r1n8t 27 7 with with IN cord-338585-ep9r1n8t 27 8 varied varied JJ cord-338585-ep9r1n8t 27 9 frequency frequency NN cord-338585-ep9r1n8t 27 10 , , , cord-338585-ep9r1n8t 27 11 the the DT cord-338585-ep9r1n8t 27 12 more more RBR cord-338585-ep9r1n8t 27 13 frequent frequent JJ cord-338585-ep9r1n8t 27 14 the the DT cord-338585-ep9r1n8t 27 15 use use NN cord-338585-ep9r1n8t 27 16 , , , cord-338585-ep9r1n8t 27 17 the the DT cord-338585-ep9r1n8t 27 18 greater great JJR cord-338585-ep9r1n8t 27 19 the the DT cord-338585-ep9r1n8t 27 20 effect effect NN cord-338585-ep9r1n8t 27 21 , , , cord-338585-ep9r1n8t 27 22 with with IN cord-338585-ep9r1n8t 27 23 twice twice RB cord-338585-ep9r1n8t 27 24 - - HYPH cord-338585-ep9r1n8t 27 25 daily daily NN cord-338585-ep9r1n8t 27 26 use use NN cord-338585-ep9r1n8t 27 27 providing provide VBG cord-338585-ep9r1n8t 27 28 maximal maximal JJ cord-338585-ep9r1n8t 27 29 effect effect NN cord-338585-ep9r1n8t 27 30 ( ( -LRB- cord-338585-ep9r1n8t 27 31 7 7 CD cord-338585-ep9r1n8t 27 32 ) ) -RRB- cord-338585-ep9r1n8t 27 33 often often RB cord-338585-ep9r1n8t 27 34 marked mark VBN cord-338585-ep9r1n8t 27 35 by by IN cord-338585-ep9r1n8t 27 36 a a DT cord-338585-ep9r1n8t 27 37 distinctive distinctive JJ cord-338585-ep9r1n8t 27 38 orange orange JJ cord-338585-ep9r1n8t 27 39 hue hue NN cord-338585-ep9r1n8t 27 40 . . . cord-338585-ep9r1n8t 28 1 DHA DHA NNP cord-338585-ep9r1n8t 28 2 's 's POS cord-338585-ep9r1n8t 28 3 action action NN cord-338585-ep9r1n8t 28 4 is be VBZ cord-338585-ep9r1n8t 28 5 limited limit VBN cord-338585-ep9r1n8t 28 6 to to IN cord-338585-ep9r1n8t 28 7 the the DT cord-338585-ep9r1n8t 28 8 outer outer JJ cord-338585-ep9r1n8t 28 9 dermal dermal JJ cord-338585-ep9r1n8t 28 10 layer layer NN cord-338585-ep9r1n8t 28 11 of of IN cord-338585-ep9r1n8t 28 12 the the DT cord-338585-ep9r1n8t 28 13 stratum stratum NN cord-338585-ep9r1n8t 28 14 corneum corneum NN cord-338585-ep9r1n8t 28 15 where where WRB cord-338585-ep9r1n8t 28 16 it -PRON- PRP cord-338585-ep9r1n8t 28 17 colors color VBZ cord-338585-ep9r1n8t 28 18 dead dead JJ cord-338585-ep9r1n8t 28 19 skin skin NN cord-338585-ep9r1n8t 28 20 cells cell NNS cord-338585-ep9r1n8t 28 21 . . . cord-338585-ep9r1n8t 29 1 There there RB cord-338585-ep9r1n8t 29 2 , , , cord-338585-ep9r1n8t 29 3 it -PRON- PRP cord-338585-ep9r1n8t 29 4 condenses condense VBZ cord-338585-ep9r1n8t 29 5 dehydratively dehydratively RB cord-338585-ep9r1n8t 29 6 with with IN cord-338585-ep9r1n8t 29 7 the the DT cord-338585-ep9r1n8t 29 8 amine amine NN cord-338585-ep9r1n8t 29 9 and and CC cord-338585-ep9r1n8t 29 10 guanidine guanidine JJ cord-338585-ep9r1n8t 29 11 nucleophiles nucleophile NNS cord-338585-ep9r1n8t 29 12 of of IN cord-338585-ep9r1n8t 29 13 lysine lysine NN cord-338585-ep9r1n8t 29 14 and and CC cord-338585-ep9r1n8t 29 15 arginine arginine NN cord-338585-ep9r1n8t 29 16 found find VBN cord-338585-ep9r1n8t 29 17 in in IN cord-338585-ep9r1n8t 29 18 keratin keratin NN cord-338585-ep9r1n8t 29 19 and and CC cord-338585-ep9r1n8t 29 20 other other JJ cord-338585-ep9r1n8t 29 21 proteins(8 proteins(8 CD cord-338585-ep9r1n8t 29 22 - - SYM cord-338585-ep9r1n8t 29 23 10 10 CD cord-338585-ep9r1n8t 29 24 ) ) -RRB- cord-338585-ep9r1n8t 29 25 via via IN cord-338585-ep9r1n8t 29 26 the the DT cord-338585-ep9r1n8t 29 27 famous famous JJ cord-338585-ep9r1n8t 29 28 Maillard Maillard NNP cord-338585-ep9r1n8t 29 29 Reaction(11 Reaction(11 NNP cord-338585-ep9r1n8t 29 30 ) ) -RRB- cord-338585-ep9r1n8t 29 31 ( ( -LRB- cord-338585-ep9r1n8t 29 32 or or CC cord-338585-ep9r1n8t 29 33 browning browning NN cord-338585-ep9r1n8t 29 34 reaction reaction NN cord-338585-ep9r1n8t 29 35 ) ) -RRB- cord-338585-ep9r1n8t 29 36 to to TO cord-338585-ep9r1n8t 29 37 afford afford VB cord-338585-ep9r1n8t 29 38 chromophores chromophore NNS cord-338585-ep9r1n8t 29 39 accounting account VBG cord-338585-ep9r1n8t 29 40 for for IN cord-338585-ep9r1n8t 29 41 the the DT cord-338585-ep9r1n8t 29 42 characteristic characteristic JJ cord-338585-ep9r1n8t 29 43 pumpkin pumpkin NN cord-338585-ep9r1n8t 29 44 color color NN cord-338585-ep9r1n8t 29 45 . . . cord-338585-ep9r1n8t 30 1 The the DT cord-338585-ep9r1n8t 30 2 Maillard Maillard NNP cord-338585-ep9r1n8t 30 3 Reaction Reaction NNP cord-338585-ep9r1n8t 30 4 , , , cord-338585-ep9r1n8t 30 5 comprises comprise VBZ cord-338585-ep9r1n8t 30 6 a a DT cord-338585-ep9r1n8t 30 7 manifold manifold NN cord-338585-ep9r1n8t 30 8 of of IN cord-338585-ep9r1n8t 30 9 reactions reaction NNS cord-338585-ep9r1n8t 30 10 including include VBG cord-338585-ep9r1n8t 30 11 Schiff Schiff NNP cord-338585-ep9r1n8t 30 12 - - HYPH cord-338585-ep9r1n8t 30 13 base base NN cord-338585-ep9r1n8t 30 14 formation formation NN cord-338585-ep9r1n8t 30 15 , , , cord-338585-ep9r1n8t 30 16 aldol aldol NN cord-338585-ep9r1n8t 30 17 - - HYPH cord-338585-ep9r1n8t 30 18 type type NN cord-338585-ep9r1n8t 30 19 condensations condensation NNS cord-338585-ep9r1n8t 30 20 , , , cord-338585-ep9r1n8t 30 21 Amadori Amadori NNP cord-338585-ep9r1n8t 30 22 rearrangements rearrangement NNS cord-338585-ep9r1n8t 30 23 , , , cord-338585-ep9r1n8t 30 24 and and CC cord-338585-ep9r1n8t 30 25 dehydrative dehydrative VB cord-338585-ep9r1n8t 30 26 and/or and/or CC cord-338585-ep9r1n8t 30 27 oxidative oxidative JJ cord-338585-ep9r1n8t 30 28 aromatization aromatization NN cord-338585-ep9r1n8t 30 29 events event NNS cord-338585-ep9r1n8t 30 30 that that WDT cord-338585-ep9r1n8t 30 31 modify modify VBP cord-338585-ep9r1n8t 30 32 lysine lysine NN cord-338585-ep9r1n8t 30 33 amines amine NNS cord-338585-ep9r1n8t 30 34 and and CC cord-338585-ep9r1n8t 30 35 give give VB cord-338585-ep9r1n8t 30 36 rise rise NN cord-338585-ep9r1n8t 30 37 to to IN cord-338585-ep9r1n8t 30 38 crosslinks crosslink NNS cord-338585-ep9r1n8t 30 39 , , , cord-338585-ep9r1n8t 30 40 ( ( -LRB- cord-338585-ep9r1n8t 30 41 12 12 CD cord-338585-ep9r1n8t 30 42 ) ) -RRB- cord-338585-ep9r1n8t 30 43 which which WDT cord-338585-ep9r1n8t 30 44 are be VBP cord-338585-ep9r1n8t 30 45 consistent consistent JJ cord-338585-ep9r1n8t 30 46 with with IN cord-338585-ep9r1n8t 30 47 other other JJ cord-338585-ep9r1n8t 30 48 advanced advanced JJ cord-338585-ep9r1n8t 30 49 glycation glycation NN cord-338585-ep9r1n8t 30 50 events event NNS cord-338585-ep9r1n8t 30 51 seen see VBN cord-338585-ep9r1n8t 30 52 in in IN cord-338585-ep9r1n8t 30 53 diabetic diabetic JJ cord-338585-ep9r1n8t 30 54 patients patient NNS cord-338585-ep9r1n8t 30 55 . . . cord-338585-ep9r1n8t 31 1 A a DT cord-338585-ep9r1n8t 31 2 recent recent JJ cord-338585-ep9r1n8t 31 3 report report NN cord-338585-ep9r1n8t 31 4 characterized characterize VBD cord-338585-ep9r1n8t 31 5 certain certain JJ cord-338585-ep9r1n8t 31 6 products product NNS cord-338585-ep9r1n8t 31 7 of of IN cord-338585-ep9r1n8t 31 8 this this DT cord-338585-ep9r1n8t 31 9 cascade cascade NN cord-338585-ep9r1n8t 31 10 in in IN cord-338585-ep9r1n8t 31 11 the the DT cord-338585-ep9r1n8t 31 12 context context NN cord-338585-ep9r1n8t 31 13 of of IN cord-338585-ep9r1n8t 31 14 several several JJ cord-338585-ep9r1n8t 31 15 reducing reduce VBG cord-338585-ep9r1n8t 31 16 sugars sugar NNS cord-338585-ep9r1n8t 31 17 , , , cord-338585-ep9r1n8t 31 18 most most RBS cord-338585-ep9r1n8t 31 19 notably notably RB cord-338585-ep9r1n8t 31 20 DHA DHA NNP cord-338585-ep9r1n8t 31 21 ( ( -LRB- cord-338585-ep9r1n8t 31 22 10 10 CD cord-338585-ep9r1n8t 31 23 ) ) -RRB- cord-338585-ep9r1n8t 31 24 , , , cord-338585-ep9r1n8t 31 25 which which WDT cord-338585-ep9r1n8t 31 26 led lead VBD cord-338585-ep9r1n8t 31 27 to to IN cord-338585-ep9r1n8t 31 28 several several JJ cord-338585-ep9r1n8t 31 29 substituted substitute VBN cord-338585-ep9r1n8t 31 30 lysine lysine NN cord-338585-ep9r1n8t 31 31 - - HYPH cord-338585-ep9r1n8t 31 32 modified modify VBN cord-338585-ep9r1n8t 31 33 pyridinium pyridinium NN cord-338585-ep9r1n8t 31 34 salts salt NNS cord-338585-ep9r1n8t 31 35 , , , cord-338585-ep9r1n8t 31 36 exemplified exemplify VBN cord-338585-ep9r1n8t 31 37 by by IN cord-338585-ep9r1n8t 31 38 compound compound NN cord-338585-ep9r1n8t 31 39 5a 5a NN cord-338585-ep9r1n8t 31 40 , , , cord-338585-ep9r1n8t 31 41 Figure figure NN cord-338585-ep9r1n8t 31 42 2 2 CD cord-338585-ep9r1n8t 31 43 ( ( -LRB- cord-338585-ep9r1n8t 31 44 and and CC cord-338585-ep9r1n8t 31 45 detailed detail VBN cord-338585-ep9r1n8t 31 46 therein therein RB cord-338585-ep9r1n8t 31 47 for for IN cord-338585-ep9r1n8t 31 48 those those DT cord-338585-ep9r1n8t 31 49 who who WP cord-338585-ep9r1n8t 31 50 might may MD cord-338585-ep9r1n8t 31 51 not not RB cord-338585-ep9r1n8t 31 52 be be VB cord-338585-ep9r1n8t 31 53 familiar familiar JJ cord-338585-ep9r1n8t 31 54 with with IN cord-338585-ep9r1n8t 31 55 this this DT cord-338585-ep9r1n8t 31 56 process process NN cord-338585-ep9r1n8t 31 57 ) ) -RRB- cord-338585-ep9r1n8t 31 58 , , , cord-338585-ep9r1n8t 31 59 which which WDT cord-338585-ep9r1n8t 31 60 is be VBZ cord-338585-ep9r1n8t 31 61 further further RB cord-338585-ep9r1n8t 31 62 capable capable JJ cord-338585-ep9r1n8t 31 63 of of IN cord-338585-ep9r1n8t 31 64 crosslinking crosslinke VBG cord-338585-ep9r1n8t 31 65 the the DT cord-338585-ep9r1n8t 31 66 nitrogen nitrogen NN cord-338585-ep9r1n8t 31 67 atoms atom NNS cord-338585-ep9r1n8t 31 68 of of IN cord-338585-ep9r1n8t 31 69 lysine lysine NN cord-338585-ep9r1n8t 31 70 and and CC cord-338585-ep9r1n8t 31 71 arginine arginine NN cord-338585-ep9r1n8t 31 72 . . . cord-338585-ep9r1n8t 32 1 Figure figure NN cord-338585-ep9r1n8t 32 2 2 2 CD cord-338585-ep9r1n8t 32 3 : : : cord-338585-ep9r1n8t 33 1 Maillard Maillard NNP cord-338585-ep9r1n8t 33 2 reaction reaction NN cord-338585-ep9r1n8t 33 3 of of IN cord-338585-ep9r1n8t 33 4 " " `` cord-338585-ep9r1n8t 33 5 3-carbon 3-carbon CD cord-338585-ep9r1n8t 33 6 " " '' cord-338585-ep9r1n8t 33 7 sugars sugar NNS cord-338585-ep9r1n8t 33 8 with with IN cord-338585-ep9r1n8t 33 9 lysine lysine NN cord-338585-ep9r1n8t 33 10 to to TO cord-338585-ep9r1n8t 33 11 give give VB cord-338585-ep9r1n8t 33 12 glycation glycation NN cord-338585-ep9r1n8t 33 13 products product NNS cord-338585-ep9r1n8t 33 14 5a 5a NN cord-338585-ep9r1n8t 33 15 - - HYPH cord-338585-ep9r1n8t 33 16 c c NN cord-338585-ep9r1n8t 33 17 by by IN cord-338585-ep9r1n8t 33 18 a a DT cord-338585-ep9r1n8t 33 19 series series NN cord-338585-ep9r1n8t 33 20 of of IN cord-338585-ep9r1n8t 33 21 reactions reaction NNS cord-338585-ep9r1n8t 33 22 including include VBG cord-338585-ep9r1n8t 33 23 aldol aldol NN cord-338585-ep9r1n8t 33 24 , , , cord-338585-ep9r1n8t 33 25 Amadori Amadori NNP cord-338585-ep9r1n8t 33 26 rearrangements rearrangement NNS cord-338585-ep9r1n8t 33 27 and and CC cord-338585-ep9r1n8t 33 28 oxidation oxidation NN cord-338585-ep9r1n8t 33 29 events event NNS cord-338585-ep9r1n8t 33 30 . . . cord-338585-ep9r1n8t 34 1 Compound compound NN cord-338585-ep9r1n8t 34 2 5b 5b NN cord-338585-ep9r1n8t 34 3 is be VBZ cord-338585-ep9r1n8t 34 4 one one CD cord-338585-ep9r1n8t 34 5 of of IN cord-338585-ep9r1n8t 34 6 several several JJ cord-338585-ep9r1n8t 34 7 conceivable conceivable JJ cord-338585-ep9r1n8t 34 8 adducts adduct NNS cord-338585-ep9r1n8t 34 9 to to IN cord-338585-ep9r1n8t 34 10 arginine arginine NN cord-338585-ep9r1n8t 34 11 resulting result VBG cord-338585-ep9r1n8t 34 12 from from IN cord-338585-ep9r1n8t 34 13 oxidation oxidation NN cord-338585-ep9r1n8t 34 14 . . . cord-338585-ep9r1n8t 35 1 The the DT cord-338585-ep9r1n8t 35 2 formation formation NN cord-338585-ep9r1n8t 35 3 of of IN cord-338585-ep9r1n8t 35 4 5c 5c CD cord-338585-ep9r1n8t 35 5 , , , cord-338585-ep9r1n8t 35 6 currently currently RB cord-338585-ep9r1n8t 35 7 unknown unknown JJ cord-338585-ep9r1n8t 35 8 , , , cord-338585-ep9r1n8t 35 9 is be VBZ cord-338585-ep9r1n8t 35 10 proposed propose VBN cord-338585-ep9r1n8t 35 11 here here RB cord-338585-ep9r1n8t 35 12 as as IN cord-338585-ep9r1n8t 35 13 an an DT cord-338585-ep9r1n8t 35 14 alternative alternative JJ cord-338585-ep9r1n8t 35 15 product product NN cord-338585-ep9r1n8t 35 16 resulting result VBG cord-338585-ep9r1n8t 35 17 from from IN cord-338585-ep9r1n8t 35 18 a a DT cord-338585-ep9r1n8t 35 19 Hantzsch Hantzsch NNP cord-338585-ep9r1n8t 35 20 - - HYPH cord-338585-ep9r1n8t 35 21 type type NN cord-338585-ep9r1n8t 35 22 pyrrole pyrrole NN cord-338585-ep9r1n8t 35 23 synthesis synthesis NN cord-338585-ep9r1n8t 35 24 . . . cord-338585-ep9r1n8t 36 1 The the DT cord-338585-ep9r1n8t 36 2 formation formation NN cord-338585-ep9r1n8t 36 3 of of IN cord-338585-ep9r1n8t 36 4 5a 5a CD cord-338585-ep9r1n8t 36 5 and and CC cord-338585-ep9r1n8t 36 6 related related JJ cord-338585-ep9r1n8t 36 7 congeners congener NNS cord-338585-ep9r1n8t 36 8 has have VBZ cord-338585-ep9r1n8t 36 9 been be VBN cord-338585-ep9r1n8t 36 10 extensively extensively RB cord-338585-ep9r1n8t 36 11 characterized characterize VBN cord-338585-ep9r1n8t 36 12 by by IN cord-338585-ep9r1n8t 36 13 HRMS HRMS NNP cord-338585-ep9r1n8t 36 14 analysis analysis NN cord-338585-ep9r1n8t 36 15 as as RB cord-338585-ep9r1n8t 36 16 well well RB cord-338585-ep9r1n8t 36 17 as as IN cord-338585-ep9r1n8t 36 18 by by IN cord-338585-ep9r1n8t 36 19 1 1 CD cord-338585-ep9r1n8t 36 20 H H NNP cord-338585-ep9r1n8t 36 21 - - HYPH cord-338585-ep9r1n8t 36 22 and and CC cord-338585-ep9r1n8t 36 23 13 13 CD cord-338585-ep9r1n8t 36 24 C C NNP cord-338585-ep9r1n8t 36 25 - - HYPH cord-338585-ep9r1n8t 36 26 NMR NMR NNP cord-338585-ep9r1n8t 36 27 , , , cord-338585-ep9r1n8t 36 28 and and CC cord-338585-ep9r1n8t 36 29 UV uv NN cord-338585-ep9r1n8t 36 30 - - HYPH cord-338585-ep9r1n8t 36 31 vis vis FW cord-338585-ep9r1n8t 36 32 spectroscopy spectroscopy NN cord-338585-ep9r1n8t 36 33 , , , cord-338585-ep9r1n8t 36 34 based base VBN cord-338585-ep9r1n8t 36 35 on on IN cord-338585-ep9r1n8t 36 36 the the DT cord-338585-ep9r1n8t 36 37 reaction reaction NN cord-338585-ep9r1n8t 36 38 of of IN cord-338585-ep9r1n8t 36 39 various various JJ cord-338585-ep9r1n8t 36 40 three three CD cord-338585-ep9r1n8t 36 41 - - HYPH cord-338585-ep9r1n8t 36 42 carbon carbon NN cord-338585-ep9r1n8t 36 43 sugars sugar NNS cord-338585-ep9r1n8t 36 44 with with IN cord-338585-ep9r1n8t 36 45 lysine lysine NN cord-338585-ep9r1n8t 36 46 . . . cord-338585-ep9r1n8t 37 1 As as IN cord-338585-ep9r1n8t 37 2 these these DT cord-338585-ep9r1n8t 37 3 aromatic aromatic JJ cord-338585-ep9r1n8t 37 4 Amadori Amadori NNP cord-338585-ep9r1n8t 37 5 products product NNS cord-338585-ep9r1n8t 37 6 are be VBP cord-338585-ep9r1n8t 37 7 capable capable JJ cord-338585-ep9r1n8t 37 8 of of IN cord-338585-ep9r1n8t 37 9 acting act VBG cord-338585-ep9r1n8t 37 10 as as IN cord-338585-ep9r1n8t 37 11 photosensitizers photosensitizer NNS cord-338585-ep9r1n8t 37 12 that that WDT cord-338585-ep9r1n8t 37 13 generate generate VBP cord-338585-ep9r1n8t 37 14 free free JJ cord-338585-ep9r1n8t 37 15 radicals radical NNS cord-338585-ep9r1n8t 37 16 ( ( -LRB- cord-338585-ep9r1n8t 37 17 13 13 CD cord-338585-ep9r1n8t 37 18 ) ) -RRB- cord-338585-ep9r1n8t 37 19 , , , cord-338585-ep9r1n8t 37 20 the the DT cord-338585-ep9r1n8t 37 21 formation formation NN cord-338585-ep9r1n8t 37 22 of of IN cord-338585-ep9r1n8t 37 23 heterocycles heterocycle NNS cord-338585-ep9r1n8t 37 24 e.g. e.g. IN cord-338585-ep9r1n8t 37 25 5c 5c NNP cord-338585-ep9r1n8t 37 26 , , , cord-338585-ep9r1n8t 37 27 which which WDT cord-338585-ep9r1n8t 37 28 might may MD cord-338585-ep9r1n8t 37 29 serve serve VB cord-338585-ep9r1n8t 37 30 as as IN cord-338585-ep9r1n8t 37 31 important important JJ cord-338585-ep9r1n8t 37 32 reductants reductant NNS cord-338585-ep9r1n8t 37 33 in in IN cord-338585-ep9r1n8t 37 34 radical radical JJ cord-338585-ep9r1n8t 37 35 processes process NNS cord-338585-ep9r1n8t 37 36 that that WDT cord-338585-ep9r1n8t 37 37 may may MD cord-338585-ep9r1n8t 37 38 contribute contribute VB cord-338585-ep9r1n8t 37 39 to to IN cord-338585-ep9r1n8t 37 40 a a DT cord-338585-ep9r1n8t 37 41 much much RB cord-338585-ep9r1n8t 37 42 more more RBR cord-338585-ep9r1n8t 37 43 extensive extensive JJ cord-338585-ep9r1n8t 37 44 array array NN cord-338585-ep9r1n8t 37 45 of of IN cord-338585-ep9r1n8t 37 46 chemical chemical JJ cord-338585-ep9r1n8t 37 47 reactions reaction NNS cord-338585-ep9r1n8t 37 48 . . . cord-338585-ep9r1n8t 38 1 Besides besides IN cord-338585-ep9r1n8t 38 2 the the DT cord-338585-ep9r1n8t 38 3 chromogenic chromogenic JJ cord-338585-ep9r1n8t 38 4 reaction reaction NN cord-338585-ep9r1n8t 38 5 that that WDT cord-338585-ep9r1n8t 38 6 occurs occur VBZ cord-338585-ep9r1n8t 38 7 between between IN cord-338585-ep9r1n8t 38 8 DHA DHA NNP cord-338585-ep9r1n8t 38 9 and and CC cord-338585-ep9r1n8t 38 10 proteins protein NNS cord-338585-ep9r1n8t 38 11 , , , cord-338585-ep9r1n8t 38 12 DHA DHA NNP cord-338585-ep9r1n8t 38 13 has have VBZ cord-338585-ep9r1n8t 38 14 also also RB cord-338585-ep9r1n8t 38 15 been be VBN cord-338585-ep9r1n8t 38 16 found find VBN cord-338585-ep9r1n8t 38 17 to to IN cord-338585-ep9r1n8t 38 18 glycate glycate VB cord-338585-ep9r1n8t 38 19 the the DT cord-338585-ep9r1n8t 38 20 nucleic nucleic JJ cord-338585-ep9r1n8t 38 21 acids acid NNS cord-338585-ep9r1n8t 38 22 : : : cord-338585-ep9r1n8t 38 23 under under IN cord-338585-ep9r1n8t 38 24 in in IN cord-338585-ep9r1n8t 38 25 vitro vitro FW cord-338585-ep9r1n8t 38 26 conditions condition NNS cord-338585-ep9r1n8t 38 27 , , , cord-338585-ep9r1n8t 38 28 reducing reduce VBG cord-338585-ep9r1n8t 38 29 sugars sugar NNS cord-338585-ep9r1n8t 39 1 are be VBP cord-338585-ep9r1n8t 39 2 known know VBN cord-338585-ep9r1n8t 39 3 to to IN cord-338585-ep9r1n8t 39 4 glycate glycate NNP cord-338585-ep9r1n8t 39 5 the the DT cord-338585-ep9r1n8t 39 6 exocyclic exocyclic JJ cord-338585-ep9r1n8t 39 7 amines amine NNS cord-338585-ep9r1n8t 39 8 of of IN cord-338585-ep9r1n8t 39 9 nucleosides nucleoside NNS cord-338585-ep9r1n8t 39 10 , , , cord-338585-ep9r1n8t 39 11 in in IN cord-338585-ep9r1n8t 39 12 particular particular JJ cord-338585-ep9r1n8t 39 13 guanine guanine NN cord-338585-ep9r1n8t 39 14 , , , cord-338585-ep9r1n8t 39 15 as as IN cord-338585-ep9r1n8t 39 16 seen see VBN cord-338585-ep9r1n8t 39 17 for for IN cord-338585-ep9r1n8t 39 18 DNA DNA NNP cord-338585-ep9r1n8t 39 19 ( ( -LRB- cord-338585-ep9r1n8t 39 20 14 14 CD cord-338585-ep9r1n8t 39 21 ) ) -RRB- cord-338585-ep9r1n8t 39 22 ( ( -LRB- cord-338585-ep9r1n8t 39 23 15 15 CD cord-338585-ep9r1n8t 39 24 ) ) -RRB- cord-338585-ep9r1n8t 39 25 ( ( -LRB- cord-338585-ep9r1n8t 39 26 16 16 CD cord-338585-ep9r1n8t 39 27 ) ) -RRB- cord-338585-ep9r1n8t 39 28 preventing prevent VBG cord-338585-ep9r1n8t 39 29 infectivity infectivity NN cord-338585-ep9r1n8t 39 30 of of IN cord-338585-ep9r1n8t 39 31 bacteriophages bacteriophage NNS cord-338585-ep9r1n8t 39 32 . . . cord-338585-ep9r1n8t 40 1 In in IN cord-338585-ep9r1n8t 40 2 addition addition NN cord-338585-ep9r1n8t 40 3 , , , cord-338585-ep9r1n8t 40 4 there there EX cord-338585-ep9r1n8t 40 5 is be VBZ cord-338585-ep9r1n8t 40 6 evidence evidence NN cord-338585-ep9r1n8t 40 7 that that IN cord-338585-ep9r1n8t 40 8 reducing reduce VBG cord-338585-ep9r1n8t 40 9 sugars sugar NNS cord-338585-ep9r1n8t 40 10 including include VBG cord-338585-ep9r1n8t 40 11 fructose fructose NN cord-338585-ep9r1n8t 40 12 ( ( -LRB- cord-338585-ep9r1n8t 40 13 a a DT cord-338585-ep9r1n8t 40 14 related relate VBN cord-338585-ep9r1n8t 40 15 keto keto NNP cord-338585-ep9r1n8t 40 16 sugar sugar NN cord-338585-ep9r1n8t 40 17 ) ) -RRB- cord-338585-ep9r1n8t 40 18 rapidly rapidly RB cord-338585-ep9r1n8t 40 19 crosslink crosslink VBP cord-338585-ep9r1n8t 40 20 lysine lysine NN cord-338585-ep9r1n8t 40 21 to to IN cord-338585-ep9r1n8t 40 22 DNA DNA NNP cord-338585-ep9r1n8t 40 23 ( ( -LRB- cord-338585-ep9r1n8t 40 24 17 17 CD cord-338585-ep9r1n8t 40 25 ) ) -RRB- cord-338585-ep9r1n8t 40 26 in in IN cord-338585-ep9r1n8t 40 27 vitro vitro FW cord-338585-ep9r1n8t 40 28 . . . cord-338585-ep9r1n8t 41 1 While while IN cord-338585-ep9r1n8t 41 2 the the DT cord-338585-ep9r1n8t 41 3 evidence evidence NN cord-338585-ep9r1n8t 41 4 for for IN cord-338585-ep9r1n8t 41 5 amino amino NN cord-338585-ep9r1n8t 41 6 - - HYPH cord-338585-ep9r1n8t 41 7 acid acid NN cord-338585-ep9r1n8t 41 8 ( ( -LRB- cord-338585-ep9r1n8t 41 9 protein protein NN cord-338585-ep9r1n8t 41 10 ) ) -RRB- cord-338585-ep9r1n8t 41 11 glycation glycation NN cord-338585-ep9r1n8t 41 12 at at IN cord-338585-ep9r1n8t 41 13 ambient ambient JJ cord-338585-ep9r1n8t 41 14 pH pH NNP cord-338585-ep9r1n8t 41 15 is be VBZ cord-338585-ep9r1n8t 41 16 much much RB cord-338585-ep9r1n8t 41 17 stronger strong JJR cord-338585-ep9r1n8t 41 18 than than IN cord-338585-ep9r1n8t 41 19 that that DT cord-338585-ep9r1n8t 41 20 for for IN cord-338585-ep9r1n8t 41 21 nucleoside nucleoside JJ cord-338585-ep9r1n8t 41 22 modification modification NN cord-338585-ep9r1n8t 41 23 , , , cord-338585-ep9r1n8t 41 24 the the DT cord-338585-ep9r1n8t 41 25 potential potential JJ cord-338585-ep9r1n8t 41 26 relevance relevance NN cord-338585-ep9r1n8t 41 27 to to IN cord-338585-ep9r1n8t 41 28 SARS SARS NNP cord-338585-ep9r1n8t 41 29 - - HYPH cord-338585-ep9r1n8t 41 30 COV-2 COV-2 NNP cord-338585-ep9r1n8t 41 31 topical topical JJ cord-338585-ep9r1n8t 41 32 prophylaxis prophylaxis NN cord-338585-ep9r1n8t 41 33 becomes become VBZ cord-338585-ep9r1n8t 41 34 apparent apparent JJ cord-338585-ep9r1n8t 41 35 . . . cord-338585-ep9r1n8t 42 1 As as IN cord-338585-ep9r1n8t 42 2 the the DT cord-338585-ep9r1n8t 42 3 outer outer JJ cord-338585-ep9r1n8t 42 4 dermal dermal JJ cord-338585-ep9r1n8t 42 5 lay lay NN cord-338585-ep9r1n8t 42 6 of of IN cord-338585-ep9r1n8t 42 7 skin skin NN cord-338585-ep9r1n8t 42 8 is be VBZ cord-338585-ep9r1n8t 42 9 expected expect VBN cord-338585-ep9r1n8t 42 10 to to TO cord-338585-ep9r1n8t 42 11 be be VB cord-338585-ep9r1n8t 42 12 much much RB cord-338585-ep9r1n8t 42 13 more more RBR cord-338585-ep9r1n8t 42 14 dehydrating dehydrating JJ cord-338585-ep9r1n8t 42 15 that that IN cord-338585-ep9r1n8t 42 16 the the DT cord-338585-ep9r1n8t 42 17 aqueous aqueous JJ cord-338585-ep9r1n8t 42 18 conditions condition NNS cord-338585-ep9r1n8t 42 19 that that WDT cord-338585-ep9r1n8t 42 20 are be VBP cord-338585-ep9r1n8t 42 21 generally generally RB cord-338585-ep9r1n8t 42 22 used use VBN cord-338585-ep9r1n8t 42 23 to to TO cord-338585-ep9r1n8t 42 24 assay assay VB cord-338585-ep9r1n8t 42 25 glycation glycation NN cord-338585-ep9r1n8t 42 26 in in IN cord-338585-ep9r1n8t 42 27 vitro vitro FW cord-338585-ep9r1n8t 42 28 , , , cord-338585-ep9r1n8t 42 29 it -PRON- PRP cord-338585-ep9r1n8t 42 30 reasonable reasonable JJ cord-338585-ep9r1n8t 42 31 to to TO cord-338585-ep9r1n8t 42 32 suspect suspect VB cord-338585-ep9r1n8t 42 33 that that IN cord-338585-ep9r1n8t 42 34 DHA DHA NNP cord-338585-ep9r1n8t 42 35 may may MD cord-338585-ep9r1n8t 42 36 be be VB cord-338585-ep9r1n8t 42 37 capable capable JJ cord-338585-ep9r1n8t 42 38 of of IN cord-338585-ep9r1n8t 42 39 modifying modify VBG cord-338585-ep9r1n8t 42 40 one one CD cord-338585-ep9r1n8t 42 41 or or CC cord-338585-ep9r1n8t 42 42 more more JJR cord-338585-ep9r1n8t 42 43 of of IN cord-338585-ep9r1n8t 42 44 the the DT cord-338585-ep9r1n8t 42 45 61 61 CD cord-338585-ep9r1n8t 42 46 lysines lysine NNS cord-338585-ep9r1n8t 42 47 and/or and/or CC cord-338585-ep9r1n8t 42 48 48 48 CD cord-338585-ep9r1n8t 42 49 arginines arginine NNS cord-338585-ep9r1n8t 42 50 on on IN cord-338585-ep9r1n8t 42 51 the the DT cord-338585-ep9r1n8t 42 52 spike spike NN cord-338585-ep9r1n8t 42 53 protein protein NN cord-338585-ep9r1n8t 42 54 ( ( -LRB- cord-338585-ep9r1n8t 42 55 Genebank Genebank NNP cord-338585-ep9r1n8t 42 56 QHD43416.1 QHD43416.1 NNP cord-338585-ep9r1n8t 42 57 ) ) -RRB- cord-338585-ep9r1n8t 42 58 , , , cord-338585-ep9r1n8t 42 59 which which WDT cord-338585-ep9r1n8t 42 60 interacts interact VBZ cord-338585-ep9r1n8t 42 61 with with IN cord-338585-ep9r1n8t 42 62 ACE2 ACE2 NNP cord-338585-ep9r1n8t 42 63 receptor receptor NN cord-338585-ep9r1n8t 42 64 enabling enable VBG cord-338585-ep9r1n8t 42 65 viral viral JJ cord-338585-ep9r1n8t 42 66 entry entry NN cord-338585-ep9r1n8t 42 67 . . . cord-338585-ep9r1n8t 43 1 Additionally additionally RB cord-338585-ep9r1n8t 43 2 , , , cord-338585-ep9r1n8t 43 3 the the DT cord-338585-ep9r1n8t 43 4 N n CD cord-338585-ep9r1n8t 43 5 - - HYPH cord-338585-ep9r1n8t 43 6 terminal terminal NN cord-338585-ep9r1n8t 43 7 domain domain NN cord-338585-ep9r1n8t 43 8 of of IN cord-338585-ep9r1n8t 43 9 the the DT cord-338585-ep9r1n8t 43 10 nucleocapsid nucleocapsid NNP cord-338585-ep9r1n8t 43 11 protein protein NN cord-338585-ep9r1n8t 43 12 , , , cord-338585-ep9r1n8t 43 13 with with IN cord-338585-ep9r1n8t 43 14 7 7 CD cord-338585-ep9r1n8t 43 15 lysines lysine NNS cord-338585-ep9r1n8t 43 16 and and CC cord-338585-ep9r1n8t 43 17 5 5 CD cord-338585-ep9r1n8t 43 18 arginines arginine NNS cord-338585-ep9r1n8t 43 19 , , , cord-338585-ep9r1n8t 43 20 which which WDT cord-338585-ep9r1n8t 43 21 provide provide VBP cord-338585-ep9r1n8t 43 22 electrostatic electrostatic JJ cord-338585-ep9r1n8t 43 23 complementarity complementarity NN cord-338585-ep9r1n8t 43 24 to to IN cord-338585-ep9r1n8t 43 25 the the DT cord-338585-ep9r1n8t 43 26 polyanionic polyanionic NNP cord-338585-ep9r1n8t 43 27 RNA RNA NNP cord-338585-ep9r1n8t 43 28 genome genome NN cord-338585-ep9r1n8t 43 29 , , , cord-338585-ep9r1n8t 43 30 may may MD cord-338585-ep9r1n8t 43 31 also also RB cord-338585-ep9r1n8t 43 32 be be VB cord-338585-ep9r1n8t 43 33 a a DT cord-338585-ep9r1n8t 43 34 target target NN cord-338585-ep9r1n8t 43 35 for for IN cord-338585-ep9r1n8t 43 36 glycation glycation NN cord-338585-ep9r1n8t 43 37 , , , cord-338585-ep9r1n8t 43 38 does do VBZ cord-338585-ep9r1n8t 43 39 the the DT cord-338585-ep9r1n8t 43 40 RNA RNA NNP cord-338585-ep9r1n8t 43 41 genome genome NN cord-338585-ep9r1n8t 43 42 itself -PRON- PRP cord-338585-ep9r1n8t 43 43 , , , cord-338585-ep9r1n8t 43 44 which which WDT cord-338585-ep9r1n8t 43 45 might may MD cord-338585-ep9r1n8t 43 46 undergo undergo VB cord-338585-ep9r1n8t 43 47 crosslinking crosslinking NN cord-338585-ep9r1n8t 43 48 to to IN cord-338585-ep9r1n8t 43 49 the the DT cord-338585-ep9r1n8t 43 50 nucleocapsid nucleocapsid NNP cord-338585-ep9r1n8t 43 51 protein protein NN cord-338585-ep9r1n8t 43 52 . . . cord-338585-ep9r1n8t 44 1 Given give VBN cord-338585-ep9r1n8t 44 2 the the DT cord-338585-ep9r1n8t 44 3 need need NN cord-338585-ep9r1n8t 44 4 to to TO cord-338585-ep9r1n8t 44 5 stanch stanch VB cord-338585-ep9r1n8t 44 6 viral viral JJ cord-338585-ep9r1n8t 44 7 transmission transmission NN cord-338585-ep9r1n8t 44 8 , , , cord-338585-ep9r1n8t 44 9 it -PRON- PRP cord-338585-ep9r1n8t 44 10 would would MD cord-338585-ep9r1n8t 44 11 be be VB cord-338585-ep9r1n8t 44 12 especially especially RB cord-338585-ep9r1n8t 44 13 attractive attractive JJ cord-338585-ep9r1n8t 44 14 to to TO cord-338585-ep9r1n8t 44 15 identify identify VB cord-338585-ep9r1n8t 44 16 a a DT cord-338585-ep9r1n8t 44 17 molecule molecule NN cord-338585-ep9r1n8t 44 18 that that WDT cord-338585-ep9r1n8t 44 19 is be VBZ cord-338585-ep9r1n8t 44 20 cheap cheap JJ cord-338585-ep9r1n8t 44 21 , , , cord-338585-ep9r1n8t 44 22 safe safe JJ cord-338585-ep9r1n8t 44 23 , , , cord-338585-ep9r1n8t 44 24 FDA FDA NNP cord-338585-ep9r1n8t 44 25 - - HYPH cord-338585-ep9r1n8t 44 26 approved approve VBN cord-338585-ep9r1n8t 44 27 , , , cord-338585-ep9r1n8t 44 28 and and CC cord-338585-ep9r1n8t 44 29 already already RB cord-338585-ep9r1n8t 44 30 found find VBN cord-338585-ep9r1n8t 44 31 in in IN cord-338585-ep9r1n8t 44 32 commercial commercial JJ cord-338585-ep9r1n8t 44 33 formulations formulation NNS cord-338585-ep9r1n8t 44 34 for for IN cord-338585-ep9r1n8t 44 35 topical topical JJ cord-338585-ep9r1n8t 44 36 application application NN cord-338585-ep9r1n8t 44 37 . . . cord-338585-ep9r1n8t 45 1 DHA DHA NNP cord-338585-ep9r1n8t 45 2 necessarily necessarily RB cord-338585-ep9r1n8t 45 3 meets meet VBZ cord-338585-ep9r1n8t 45 4 all all DT cord-338585-ep9r1n8t 45 5 of of IN cord-338585-ep9r1n8t 45 6 these these DT cord-338585-ep9r1n8t 45 7 characteristics characteristic NNS cord-338585-ep9r1n8t 45 8 . . . cord-338585-ep9r1n8t 46 1 Taken take VBN cord-338585-ep9r1n8t 46 2 together together RB cord-338585-ep9r1n8t 46 3 , , , cord-338585-ep9r1n8t 46 4 a a DT cord-338585-ep9r1n8t 46 5 solid solid JJ cord-338585-ep9r1n8t 46 6 body body NN cord-338585-ep9r1n8t 46 7 of of IN cord-338585-ep9r1n8t 46 8 scientific scientific JJ cord-338585-ep9r1n8t 46 9 evidence evidence NN cord-338585-ep9r1n8t 46 10 provides provide VBZ cord-338585-ep9r1n8t 46 11 a a DT cord-338585-ep9r1n8t 46 12 reasonable reasonable JJ cord-338585-ep9r1n8t 46 13 chemical chemical JJ cord-338585-ep9r1n8t 46 14 basis basis NN cord-338585-ep9r1n8t 46 15 to to TO cord-338585-ep9r1n8t 46 16 support support VB cord-338585-ep9r1n8t 46 17 the the DT cord-338585-ep9r1n8t 46 18 hypothesis hypothesis NN cord-338585-ep9r1n8t 46 19 that that IN cord-338585-ep9r1n8t 46 20 DHA DHA NNP cord-338585-ep9r1n8t 46 21 may may MD cord-338585-ep9r1n8t 46 22 dehydratively dehydratively RB cord-338585-ep9r1n8t 46 23 glycate glycate VB cord-338585-ep9r1n8t 46 24 viral viral JJ cord-338585-ep9r1n8t 46 25 proteins protein NNS cord-338585-ep9r1n8t 46 26 and/or and/or CC cord-338585-ep9r1n8t 46 27 viral viral JJ cord-338585-ep9r1n8t 46 28 genomic genomic JJ cord-338585-ep9r1n8t 46 29 RNA RNA NNP cord-338585-ep9r1n8t 46 30 , , , cord-338585-ep9r1n8t 46 31 which which WDT cord-338585-ep9r1n8t 46 32 would would MD cord-338585-ep9r1n8t 46 33 in in IN cord-338585-ep9r1n8t 46 34 turn turn NN cord-338585-ep9r1n8t 46 35 be be VB cord-338585-ep9r1n8t 46 36 expected expect VBN cord-338585-ep9r1n8t 46 37 to to TO cord-338585-ep9r1n8t 46 38 inactivate inactivate VB cord-338585-ep9r1n8t 46 39 the the DT cord-338585-ep9r1n8t 46 40 virus virus NN cord-338585-ep9r1n8t 46 41 , , , cord-338585-ep9r1n8t 46 42 thus thus RB cord-338585-ep9r1n8t 46 43 prophylactically prophylactically RB cord-338585-ep9r1n8t 46 44 protecting protect VBG cord-338585-ep9r1n8t 46 45 the the DT cord-338585-ep9r1n8t 46 46 wearer wearer NN cord-338585-ep9r1n8t 46 47 from from IN cord-338585-ep9r1n8t 46 48 facial facial JJ cord-338585-ep9r1n8t 46 49 transmission transmission NN cord-338585-ep9r1n8t 46 50 . . . cord-338585-ep9r1n8t 47 1 Finally finally RB cord-338585-ep9r1n8t 47 2 , , , cord-338585-ep9r1n8t 47 3 independent independent JJ cord-338585-ep9r1n8t 47 4 support support NN cord-338585-ep9r1n8t 47 5 for for IN cord-338585-ep9r1n8t 47 6 DHA DHA NNP cord-338585-ep9r1n8t 47 7 application application NN cord-338585-ep9r1n8t 47 8 is be VBZ cord-338585-ep9r1n8t 47 9 found find VBN cord-338585-ep9r1n8t 47 10 in in IN cord-338585-ep9r1n8t 47 11 an an DT cord-338585-ep9r1n8t 47 12 isolated isolated JJ cord-338585-ep9r1n8t 47 13 report report NN cord-338585-ep9r1n8t 47 14 that that WDT cord-338585-ep9r1n8t 47 15 describes describe VBZ cord-338585-ep9r1n8t 47 16 the the DT cord-338585-ep9r1n8t 47 17 antifungal antifungal JJ cord-338585-ep9r1n8t 47 18 activity activity NN cord-338585-ep9r1n8t 47 19 of of IN cord-338585-ep9r1n8t 47 20 DHA DHA NNP cord-338585-ep9r1n8t 47 21 to to TO cord-338585-ep9r1n8t 47 22 treat treat VB cord-338585-ep9r1n8t 47 23 dermatomycosis(18 dermatomycosis(18 NNP cord-338585-ep9r1n8t 47 24 ) ) -RRB- cord-338585-ep9r1n8t 47 25 further further RB cord-338585-ep9r1n8t 47 26 highlighting highlight VBG cord-338585-ep9r1n8t 47 27 potential potential JJ cord-338585-ep9r1n8t 47 28 biocidal biocidal NN cord-338585-ep9r1n8t 47 29 activity activity NN cord-338585-ep9r1n8t 47 30 . . . cord-338585-ep9r1n8t 48 1 In in IN cord-338585-ep9r1n8t 48 2 the the DT cord-338585-ep9r1n8t 48 3 absence absence NN cord-338585-ep9r1n8t 48 4 of of IN cord-338585-ep9r1n8t 48 5 a a DT cord-338585-ep9r1n8t 48 6 clinical clinical JJ cord-338585-ep9r1n8t 48 7 study study NN cord-338585-ep9r1n8t 48 8 , , , cord-338585-ep9r1n8t 48 9 I -PRON- PRP cord-338585-ep9r1n8t 48 10 can can MD cord-338585-ep9r1n8t 48 11 only only RB cord-338585-ep9r1n8t 48 12 provide provide VB cord-338585-ep9r1n8t 48 13 sound sound JJ cord-338585-ep9r1n8t 48 14 biochemical biochemical JJ cord-338585-ep9r1n8t 48 15 evidence evidence NN cord-338585-ep9r1n8t 48 16 to to TO cord-338585-ep9r1n8t 48 17 support support VB cord-338585-ep9r1n8t 48 18 this this DT cord-338585-ep9r1n8t 48 19 hypothesis hypothesis NN cord-338585-ep9r1n8t 48 20 to to TO cord-338585-ep9r1n8t 48 21 highlight highlight VB cord-338585-ep9r1n8t 48 22 the the DT cord-338585-ep9r1n8t 48 23 chemical chemical JJ cord-338585-ep9r1n8t 48 24 rationale rationale NN cord-338585-ep9r1n8t 48 25 for for IN cord-338585-ep9r1n8t 48 26 exploring explore VBG cord-338585-ep9r1n8t 48 27 the the DT cord-338585-ep9r1n8t 48 28 potential potential NN cord-338585-ep9r1n8t 48 29 of of IN cord-338585-ep9r1n8t 48 30 studying study VBG cord-338585-ep9r1n8t 48 31 whether whether IN cord-338585-ep9r1n8t 48 32 DHA DHA NNP cord-338585-ep9r1n8t 48 33 could could MD cord-338585-ep9r1n8t 48 34 protect protect VB cord-338585-ep9r1n8t 48 35 against against IN cord-338585-ep9r1n8t 48 36 SARS SARS NNP cord-338585-ep9r1n8t 48 37 - - HYPH cord-338585-ep9r1n8t 48 38 COV-2 COV-2 NNP cord-338585-ep9r1n8t 48 39 transition transition NN cord-338585-ep9r1n8t 48 40 . . . cord-338585-ep9r1n8t 49 1 Herein herein RB cord-338585-ep9r1n8t 49 2 , , , cord-338585-ep9r1n8t 49 3 several several JJ cord-338585-ep9r1n8t 49 4 studies study NNS cord-338585-ep9r1n8t 49 5 are be VBP cord-338585-ep9r1n8t 49 6 proposed propose VBN cord-338585-ep9r1n8t 49 7 . . . cord-338585-ep9r1n8t 50 1 To to TO cord-338585-ep9r1n8t 50 2 start start VB cord-338585-ep9r1n8t 50 3 , , , cord-338585-ep9r1n8t 50 4 studies study NNS cord-338585-ep9r1n8t 50 5 could could MD cord-338585-ep9r1n8t 50 6 be be VB cord-338585-ep9r1n8t 50 7 undertaken undertake VBN cord-338585-ep9r1n8t 50 8 to to TO cord-338585-ep9r1n8t 50 9 score score VB cord-338585-ep9r1n8t 50 10 viral viral JJ cord-338585-ep9r1n8t 50 11 transfectivity transfectivity NN cord-338585-ep9r1n8t 50 12 following follow VBG cord-338585-ep9r1n8t 50 13 application application NN cord-338585-ep9r1n8t 50 14 of of IN cord-338585-ep9r1n8t 50 15 live live JJ cord-338585-ep9r1n8t 50 16 virus virus NN cord-338585-ep9r1n8t 50 17 to to IN cord-338585-ep9r1n8t 50 18 non non JJ cord-338585-ep9r1n8t 50 19 - - JJ cord-338585-ep9r1n8t 50 20 living living JJ cord-338585-ep9r1n8t 50 21 surfaces surface NNS cord-338585-ep9r1n8t 50 22 ( ( -LRB- cord-338585-ep9r1n8t 50 23 19 19 CD cord-338585-ep9r1n8t 50 24 ) ) -RRB- cord-338585-ep9r1n8t 50 25 that that WDT cord-338585-ep9r1n8t 50 26 have have VBP cord-338585-ep9r1n8t 50 27 been be VBN cord-338585-ep9r1n8t 50 28 coated coat VBN cord-338585-ep9r1n8t 50 29 with with IN cord-338585-ep9r1n8t 50 30 DHA DHA NNP cord-338585-ep9r1n8t 50 31 compared compare VBN cord-338585-ep9r1n8t 50 32 to to IN cord-338585-ep9r1n8t 50 33 those those DT cord-338585-ep9r1n8t 50 34 that that WDT cord-338585-ep9r1n8t 50 35 have have VBP cord-338585-ep9r1n8t 50 36 not not RB cord-338585-ep9r1n8t 50 37 . . . cord-338585-ep9r1n8t 51 1 It -PRON- PRP cord-338585-ep9r1n8t 51 2 may may MD cord-338585-ep9r1n8t 51 3 be be VB cord-338585-ep9r1n8t 51 4 possible possible JJ cord-338585-ep9r1n8t 51 5 to to TO cord-338585-ep9r1n8t 51 6 explore explore VB cord-338585-ep9r1n8t 51 7 a a DT cord-338585-ep9r1n8t 51 8 human human JJ cord-338585-ep9r1n8t 51 9 trial trial NN cord-338585-ep9r1n8t 51 10 , , , cord-338585-ep9r1n8t 51 11 which which WDT cord-338585-ep9r1n8t 51 12 would would MD cord-338585-ep9r1n8t 51 13 involve involve VB cord-338585-ep9r1n8t 51 14 little little JJ cord-338585-ep9r1n8t 51 15 concern concern NN cord-338585-ep9r1n8t 51 16 for for IN cord-338585-ep9r1n8t 51 17 side side JJ cord-338585-ep9r1n8t 51 18 effects effect NNS cord-338585-ep9r1n8t 51 19 . . . cord-338585-ep9r1n8t 52 1 For for IN cord-338585-ep9r1n8t 52 2 example example NN cord-338585-ep9r1n8t 52 3 , , , cord-338585-ep9r1n8t 52 4 in in IN cord-338585-ep9r1n8t 52 5 assisted assist VBN cord-338585-ep9r1n8t 52 6 living living NN cord-338585-ep9r1n8t 52 7 facilities facility NNS cord-338585-ep9r1n8t 52 8 where where WRB cord-338585-ep9r1n8t 52 9 there there EX cord-338585-ep9r1n8t 52 10 is be VBZ cord-338585-ep9r1n8t 52 11 the the DT cord-338585-ep9r1n8t 52 12 highest high JJS cord-338585-ep9r1n8t 52 13 risk risk NN cord-338585-ep9r1n8t 52 14 to to IN cord-338585-ep9r1n8t 52 15 life life NN cord-338585-ep9r1n8t 52 16 , , , cord-338585-ep9r1n8t 52 17 residents resident NNS cord-338585-ep9r1n8t 52 18 could could MD cord-338585-ep9r1n8t 52 19 be be VB cord-338585-ep9r1n8t 52 20 asked ask VBN cord-338585-ep9r1n8t 52 21 to to TO cord-338585-ep9r1n8t 52 22 apply apply VB cord-338585-ep9r1n8t 52 23 a a DT cord-338585-ep9r1n8t 52 24 commercially commercially RB cord-338585-ep9r1n8t 52 25 available available JJ cord-338585-ep9r1n8t 52 26 DHA dha NN cord-338585-ep9r1n8t 52 27 - - HYPH cord-338585-ep9r1n8t 52 28 containing contain VBG cord-338585-ep9r1n8t 52 29 cream cream NN cord-338585-ep9r1n8t 52 30 to to TO cord-338585-ep9r1n8t 52 31 face face NN cord-338585-ep9r1n8t 52 32 and and CC cord-338585-ep9r1n8t 52 33 hands hand NNS cord-338585-ep9r1n8t 52 34 . . . cord-338585-ep9r1n8t 53 1 Likewise likewise RB cord-338585-ep9r1n8t 53 2 , , , cord-338585-ep9r1n8t 53 3 health health NN cord-338585-ep9r1n8t 53 4 workers worker NNS cord-338585-ep9r1n8t 53 5 , , , cord-338585-ep9r1n8t 53 6 who who WP cord-338585-ep9r1n8t 53 7 are be VBP cord-338585-ep9r1n8t 53 8 typically typically RB cord-338585-ep9r1n8t 53 9 at at IN cord-338585-ep9r1n8t 53 10 higher high JJR cord-338585-ep9r1n8t 53 11 risk risk NN cord-338585-ep9r1n8t 53 12 of of IN cord-338585-ep9r1n8t 53 13 exposure exposure NN cord-338585-ep9r1n8t 53 14 , , , cord-338585-ep9r1n8t 53 15 could could MD cord-338585-ep9r1n8t 53 16 volunteer volunteer VB cord-338585-ep9r1n8t 53 17 to to TO cord-338585-ep9r1n8t 53 18 apply apply VB cord-338585-ep9r1n8t 53 19 self self NN cord-338585-ep9r1n8t 53 20 - - HYPH cord-338585-ep9r1n8t 53 21 tanning tan VBG cord-338585-ep9r1n8t 53 22 cream cream NN cord-338585-ep9r1n8t 53 23 to to IN cord-338585-ep9r1n8t 53 24 hands hand NNS cord-338585-ep9r1n8t 53 25 and and CC cord-338585-ep9r1n8t 53 26 face face VB cord-338585-ep9r1n8t 53 27 on on IN cord-338585-ep9r1n8t 53 28 semi semi JJ cord-338585-ep9r1n8t 53 29 - - JJ cord-338585-ep9r1n8t 53 30 daily daily JJ cord-338585-ep9r1n8t 53 31 basis basis NN cord-338585-ep9r1n8t 53 32 . . . cord-338585-ep9r1n8t 54 1 Incidence incidence NN cord-338585-ep9r1n8t 54 2 of of IN cord-338585-ep9r1n8t 54 3 infection infection NN cord-338585-ep9r1n8t 54 4 could could MD cord-338585-ep9r1n8t 54 5 then then RB cord-338585-ep9r1n8t 54 6 be be VB cord-338585-ep9r1n8t 54 7 scored score VBN cord-338585-ep9r1n8t 54 8 in in IN cord-338585-ep9r1n8t 54 9 relation relation NN cord-338585-ep9r1n8t 54 10 to to IN cord-338585-ep9r1n8t 54 11 the the DT cord-338585-ep9r1n8t 54 12 DHA DHA NNP cord-338585-ep9r1n8t 54 13 application application NN cord-338585-ep9r1n8t 54 14 or or CC cord-338585-ep9r1n8t 54 15 lack lack NN cord-338585-ep9r1n8t 54 16 thereof thereof RB cord-338585-ep9r1n8t 54 17 . . . cord-338585-ep9r1n8t 55 1 Together together RB cord-338585-ep9r1n8t 55 2 , , , cord-338585-ep9r1n8t 55 3 such such JJ cord-338585-ep9r1n8t 55 4 studies study NNS cord-338585-ep9r1n8t 55 5 would would MD cord-338585-ep9r1n8t 55 6 systematically systematically RB cord-338585-ep9r1n8t 55 7 advance advance VB cord-338585-ep9r1n8t 55 8 this this DT cord-338585-ep9r1n8t 55 9 hypothesis hypothesis NN cord-338585-ep9r1n8t 55 10 from from IN cord-338585-ep9r1n8t 55 11 well well RB cord-338585-ep9r1n8t 55 12 - - HYPH cord-338585-ep9r1n8t 55 13 established establish VBN cord-338585-ep9r1n8t 55 14 in in IN cord-338585-ep9r1n8t 55 15 vitro vitro FW cord-338585-ep9r1n8t 55 16 results result VBZ cord-338585-ep9r1n8t 55 17 to to IN cord-338585-ep9r1n8t 55 18 an an DT cord-338585-ep9r1n8t 55 19 easily easily RB cord-338585-ep9r1n8t 55 20 monitored monitor VBN cord-338585-ep9r1n8t 55 21 clinical clinical JJ cord-338585-ep9r1n8t 55 22 trial trial NN cord-338585-ep9r1n8t 55 23 , , , cord-338585-ep9r1n8t 55 24 that that DT cord-338585-ep9r1n8t 55 25 would would MD cord-338585-ep9r1n8t 55 26 lead lead VB cord-338585-ep9r1n8t 55 27 to to IN cord-338585-ep9r1n8t 55 28 a a DT cord-338585-ep9r1n8t 55 29 medically medically RB cord-338585-ep9r1n8t 55 30 justified justified JJ cord-338585-ep9r1n8t 55 31 recommendation recommendation NN cord-338585-ep9r1n8t 55 32 for for IN cord-338585-ep9r1n8t 55 33 daily daily JJ cord-338585-ep9r1n8t 55 34 topical topical JJ cord-338585-ep9r1n8t 55 35 prophylactic prophylactic JJ cord-338585-ep9r1n8t 55 36 application application NN cord-338585-ep9r1n8t 55 37 of of IN cord-338585-ep9r1n8t 55 38 DHA DHA NNP cord-338585-ep9r1n8t 55 39 to to IN cord-338585-ep9r1n8t 55 40 the the DT cord-338585-ep9r1n8t 55 41 face face NN cord-338585-ep9r1n8t 55 42 and and CC cord-338585-ep9r1n8t 55 43 hands hand NNS cord-338585-ep9r1n8t 55 44 for for IN cord-338585-ep9r1n8t 55 45 reducing reduce VBG cord-338585-ep9r1n8t 55 46 SARS SARS NNP cord-338585-ep9r1n8t 55 47 - - HYPH cord-338585-ep9r1n8t 55 48 COV-2 COV-2 NNP cord-338585-ep9r1n8t 55 49 infection infection NN cord-338585-ep9r1n8t 55 50 . . . cord-338585-ep9r1n8t 56 1 As as IN cord-338585-ep9r1n8t 56 2 a a DT cord-338585-ep9r1n8t 56 3 chemist chemist NN cord-338585-ep9r1n8t 56 4 , , , cord-338585-ep9r1n8t 56 5 I -PRON- PRP cord-338585-ep9r1n8t 56 6 have have VBP cord-338585-ep9r1n8t 56 7 based base VBN cord-338585-ep9r1n8t 56 8 this this DT cord-338585-ep9r1n8t 56 9 proposal proposal NN cord-338585-ep9r1n8t 56 10 on on IN cord-338585-ep9r1n8t 56 11 sound sound JJ cord-338585-ep9r1n8t 56 12 biochemical biochemical JJ cord-338585-ep9r1n8t 56 13 logic logic NN cord-338585-ep9r1n8t 56 14 and and CC cord-338585-ep9r1n8t 56 15 wellestablished wellestablishe VBN cord-338585-ep9r1n8t 56 16 in in IN cord-338585-ep9r1n8t 56 17 vitro vitro FW cord-338585-ep9r1n8t 56 18 evidence evidence NN cord-338585-ep9r1n8t 56 19 of of IN cord-338585-ep9r1n8t 56 20 DHA DHA NNP cord-338585-ep9r1n8t 56 21 - - HYPH cord-338585-ep9r1n8t 56 22 based base VBN cord-338585-ep9r1n8t 56 23 glycation glycation NN cord-338585-ep9r1n8t 56 24 with with IN cord-338585-ep9r1n8t 56 25 citations citation NNS cord-338585-ep9r1n8t 56 26 of of IN cord-338585-ep9r1n8t 56 27 peer peer NN cord-338585-ep9r1n8t 56 28 - - HYPH cord-338585-ep9r1n8t 56 29 reviewed review VBN cord-338585-ep9r1n8t 56 30 scientific scientific JJ cord-338585-ep9r1n8t 56 31 publications publication NNS cord-338585-ep9r1n8t 56 32 . . . cord-338585-ep9r1n8t 57 1 With with IN cord-338585-ep9r1n8t 57 2 limited limited JJ cord-338585-ep9r1n8t 57 3 funding funding NN cord-338585-ep9r1n8t 57 4 and and CC cord-338585-ep9r1n8t 57 5 no no DT cord-338585-ep9r1n8t 57 6 access access NN cord-338585-ep9r1n8t 57 7 to to IN cord-338585-ep9r1n8t 57 8 viral viral JJ cord-338585-ep9r1n8t 57 9 strains strain NNS cord-338585-ep9r1n8t 57 10 in in IN cord-338585-ep9r1n8t 57 11 my -PRON- PRP$ cord-338585-ep9r1n8t 57 12 own own JJ cord-338585-ep9r1n8t 57 13 lab lab NN cord-338585-ep9r1n8t 57 14 , , , cord-338585-ep9r1n8t 57 15 I -PRON- PRP cord-338585-ep9r1n8t 57 16 submit submit VBP cord-338585-ep9r1n8t 57 17 this this DT cord-338585-ep9r1n8t 57 18 Hypothesis Hypothesis NNP cord-338585-ep9r1n8t 57 19 in in IN cord-338585-ep9r1n8t 57 20 the the DT cord-338585-ep9r1n8t 57 21 hope hope NN cord-338585-ep9r1n8t 57 22 that that IN cord-338585-ep9r1n8t 57 23 it -PRON- PRP cord-338585-ep9r1n8t 57 24 will will MD cord-338585-ep9r1n8t 57 25 inspire inspire VB cord-338585-ep9r1n8t 57 26 medical medical JJ cord-338585-ep9r1n8t 57 27 researchers researcher NNS cord-338585-ep9r1n8t 57 28 who who WP cord-338585-ep9r1n8t 57 29 are be VBP cord-338585-ep9r1n8t 57 30 equipped equip VBN cord-338585-ep9r1n8t 57 31 with with IN cord-338585-ep9r1n8t 57 32 the the DT cord-338585-ep9r1n8t 57 33 proper proper JJ cord-338585-ep9r1n8t 57 34 biosafety biosafety NN cord-338585-ep9r1n8t 57 35 containment containment NN cord-338585-ep9r1n8t 57 36 level-3 level-3 NN cord-338585-ep9r1n8t 57 37 and and CC cord-338585-ep9r1n8t 57 38 clinicians clinician NNS cord-338585-ep9r1n8t 57 39 who who WP cord-338585-ep9r1n8t 57 40 are be VBP cord-338585-ep9r1n8t 57 41 certified certify VBN cord-338585-ep9r1n8t 57 42 to to TO cord-338585-ep9r1n8t 57 43 treat treat VB cord-338585-ep9r1n8t 57 44 high high JJ cord-338585-ep9r1n8t 57 45 - - HYPH cord-338585-ep9r1n8t 57 46 risk risk NN cord-338585-ep9r1n8t 57 47 individuals individual NNS cord-338585-ep9r1n8t 57 48 in in IN cord-338585-ep9r1n8t 57 49 clinical clinical JJ cord-338585-ep9r1n8t 57 50 settings setting NNS cord-338585-ep9r1n8t 57 51 / / SYM cord-338585-ep9r1n8t 57 52 care care NN cord-338585-ep9r1n8t 57 53 facilities facility NNS cord-338585-ep9r1n8t 57 54 to to TO cord-338585-ep9r1n8t 57 55 consider consider VB cord-338585-ep9r1n8t 57 56 the the DT cord-338585-ep9r1n8t 57 57 proposed propose VBN cord-338585-ep9r1n8t 57 58 experiments experiment NNS cord-338585-ep9r1n8t 57 59 . . . cord-338585-ep9r1n8t 58 1 In in IN cord-338585-ep9r1n8t 58 2 no no DT cord-338585-ep9r1n8t 58 3 way way NN cord-338585-ep9r1n8t 58 4 do do VBP cord-338585-ep9r1n8t 58 5 I -PRON- PRP cord-338585-ep9r1n8t 58 6 advocate advocate VB cord-338585-ep9r1n8t 58 7 ingestion ingestion NN cord-338585-ep9r1n8t 58 8 of of IN cord-338585-ep9r1n8t 58 9 DHA DHA NNP cord-338585-ep9r1n8t 58 10 . . . cord-338585-ep9r1n8t 59 1 Nor nor CC cord-338585-ep9r1n8t 59 2 do do VBP cord-338585-ep9r1n8t 59 3 I -PRON- PRP cord-338585-ep9r1n8t 59 4 advocate advocate VB cord-338585-ep9r1n8t 59 5 use use NN cord-338585-ep9r1n8t 59 6 of of IN cord-338585-ep9r1n8t 59 7 self self NN cord-338585-ep9r1n8t 59 8 - - HYPH cord-338585-ep9r1n8t 59 9 tanning tan VBG cord-338585-ep9r1n8t 59 10 products product NNS cord-338585-ep9r1n8t 59 11 as as IN cord-338585-ep9r1n8t 59 12 a a DT cord-338585-ep9r1n8t 59 13 prophylactic prophylactic NN cord-338585-ep9r1n8t 59 14 until until IN cord-338585-ep9r1n8t 59 15 these these DT cord-338585-ep9r1n8t 59 16 experiments experiment NNS cord-338585-ep9r1n8t 59 17 are be VBP cord-338585-ep9r1n8t 59 18 properly properly RB cord-338585-ep9r1n8t 59 19 conducted conduct VBN cord-338585-ep9r1n8t 59 20 . . . cord-338585-ep9r1n8t 60 1 Furthermore furthermore RB cord-338585-ep9r1n8t 60 2 , , , cord-338585-ep9r1n8t 60 3 in in IN cord-338585-ep9r1n8t 60 4 no no DT cord-338585-ep9r1n8t 60 5 way way NN cord-338585-ep9r1n8t 60 6 do do VBP cord-338585-ep9r1n8t 60 7 I -PRON- PRP cord-338585-ep9r1n8t 60 8 suggest suggest VB cord-338585-ep9r1n8t 60 9 DHA DHA NNP cord-338585-ep9r1n8t 60 10 applications application NNS cord-338585-ep9r1n8t 60 11 should should MD cord-338585-ep9r1n8t 60 12 obviate obviate VB cord-338585-ep9r1n8t 60 13 wearing wear VBG cord-338585-ep9r1n8t 60 14 a a DT cord-338585-ep9r1n8t 60 15 mask mask NN cord-338585-ep9r1n8t 60 16 , , , cord-338585-ep9r1n8t 60 17 social social JJ cord-338585-ep9r1n8t 60 18 distancing distancing NN cord-338585-ep9r1n8t 60 19 or or CC cord-338585-ep9r1n8t 60 20 hand hand NN cord-338585-ep9r1n8t 60 21 washing washing NN cord-338585-ep9r1n8t 60 22 . . . cord-338585-ep9r1n8t 61 1 The the DT cord-338585-ep9r1n8t 61 2 influence influence NN cord-338585-ep9r1n8t 61 3 of of IN cord-338585-ep9r1n8t 61 4 dihydroxyacetone dihydroxyacetone NN cord-338585-ep9r1n8t 61 5 upon upon IN cord-338585-ep9r1n8t 61 6 the the DT cord-338585-ep9r1n8t 61 7 blood blood NN cord-338585-ep9r1n8t 61 8 sugar sugar NN cord-338585-ep9r1n8t 61 9 and and CC cord-338585-ep9r1n8t 61 10 glycosuria glycosuria NNP cord-338585-ep9r1n8t 61 11 Investigative Investigative NNP cord-338585-ep9r1n8t 61 12 studies study NNS cord-338585-ep9r1n8t 61 13 with with IN cord-338585-ep9r1n8t 61 14 the the DT cord-338585-ep9r1n8t 61 15 skin skin NN cord-338585-ep9r1n8t 61 16 coloring color VBG cord-338585-ep9r1n8t 61 17 agents agent NNS cord-338585-ep9r1n8t 61 18 dihydroxyacetone dihydroxyacetone NNP cord-338585-ep9r1n8t 61 19 and and CC cord-338585-ep9r1n8t 61 20 glyoxal glyoxal NNP cord-338585-ep9r1n8t 61 21 -preliminary -preliminary CD cord-338585-ep9r1n8t 61 22 report report NN cord-338585-ep9r1n8t 61 23 Staining staining NN cord-338585-ep9r1n8t 61 24 of of IN cord-338585-ep9r1n8t 61 25 Skin skin NN cord-338585-ep9r1n8t 61 26 with with IN cord-338585-ep9r1n8t 61 27 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 61 28 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 61 29 in in IN cord-338585-ep9r1n8t 61 30 a a DT cord-338585-ep9r1n8t 61 31 New new JJ cord-338585-ep9r1n8t 61 32 formulation formulation NN cord-338585-ep9r1n8t 61 33 -A -A : cord-338585-ep9r1n8t 61 34 powerful powerful JJ cord-338585-ep9r1n8t 61 35 therapeutic therapeutic JJ cord-338585-ep9r1n8t 61 36 option option NN cord-338585-ep9r1n8t 61 37 in in IN cord-338585-ep9r1n8t 61 38 vitiligo vitiligo NN cord-338585-ep9r1n8t 61 39 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 61 40 and and CC cord-338585-ep9r1n8t 61 41 sunless sunless JJ cord-338585-ep9r1n8t 61 42 tanning tanning NN cord-338585-ep9r1n8t 61 43 : : : cord-338585-ep9r1n8t 61 44 Knowledge knowledge NN cord-338585-ep9r1n8t 61 45 , , , cord-338585-ep9r1n8t 61 46 myths myth NNS cord-338585-ep9r1n8t 61 47 , , , cord-338585-ep9r1n8t 61 48 and and CC cord-338585-ep9r1n8t 61 49 current current JJ cord-338585-ep9r1n8t 61 50 understanding understanding NN cord-338585-ep9r1n8t 61 51 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 61 52 : : : cord-338585-ep9r1n8t 62 1 An an DT cord-338585-ep9r1n8t 62 2 Updated update VBN cord-338585-ep9r1n8t 62 3 Insight Insight NNP cord-338585-ep9r1n8t 62 4 into into IN cord-338585-ep9r1n8t 62 5 an an DT cord-338585-ep9r1n8t 62 6 Important Important NNP cord-338585-ep9r1n8t 62 7 Bioproduct Bioproduct NNP cord-338585-ep9r1n8t 62 8 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 62 9 -A -A HYPH cord-338585-ep9r1n8t 62 10 Suntan suntan NN cord-338585-ep9r1n8t 62 11 Simulating simulate VBG cord-338585-ep9r1n8t 62 12 Agent Agent NNP cord-338585-ep9r1n8t 62 13 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 62 14 ( ( -LRB- cord-338585-ep9r1n8t 62 15 DHA DHA NNP cord-338585-ep9r1n8t 62 16 ) ) -RRB- cord-338585-ep9r1n8t 63 1 -A -A : cord-338585-ep9r1n8t 63 2 Keratin Keratin NNP cord-338585-ep9r1n8t 63 3 Coloring Coloring NNP cord-338585-ep9r1n8t 63 4 Agent Agent NNP cord-338585-ep9r1n8t 63 5 Reaction Reaction NNP cord-338585-ep9r1n8t 63 6 of of IN cord-338585-ep9r1n8t 63 7 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 63 8 ( ( -LRB- cord-338585-ep9r1n8t 63 9 DHA DHA NNP cord-338585-ep9r1n8t 63 10 ) ) -RRB- cord-338585-ep9r1n8t 63 11 with with IN cord-338585-ep9r1n8t 63 12 Human Human NNP cord-338585-ep9r1n8t 63 13 Skin skin NN cord-338585-ep9r1n8t 63 14 Callus callus NN cord-338585-ep9r1n8t 63 15 and and CC cord-338585-ep9r1n8t 63 16 Amino Amino NNP cord-338585-ep9r1n8t 63 17 Compounds compound NNS cord-338585-ep9r1n8t 63 18 Triosidines Triosidines NNPS cord-338585-ep9r1n8t 63 19 : : : cord-338585-ep9r1n8t 63 20 novel novel JJ cord-338585-ep9r1n8t 63 21 Maillard Maillard NNP cord-338585-ep9r1n8t 63 22 reaction reaction NN cord-338585-ep9r1n8t 63 23 products product NNS cord-338585-ep9r1n8t 63 24 and and CC cord-338585-ep9r1n8t 63 25 cross cross NN cord-338585-ep9r1n8t 63 26 - - NN cord-338585-ep9r1n8t 63 27 links link NNS cord-338585-ep9r1n8t 63 28 from from IN cord-338585-ep9r1n8t 63 29 the the DT cord-338585-ep9r1n8t 63 30 reaction reaction NN cord-338585-ep9r1n8t 63 31 of of IN cord-338585-ep9r1n8t 63 32 triose triose NN cord-338585-ep9r1n8t 63 33 sugars sugar NNS cord-338585-ep9r1n8t 63 34 with with IN cord-338585-ep9r1n8t 63 35 lysine lysine NN cord-338585-ep9r1n8t 63 36 and and CC cord-338585-ep9r1n8t 63 37 arginine arginine NN cord-338585-ep9r1n8t 63 38 residues residue NNS cord-338585-ep9r1n8t 64 1 A a DT cord-338585-ep9r1n8t 64 2 synthesis synthesis NN cord-338585-ep9r1n8t 64 3 of of IN cord-338585-ep9r1n8t 64 4 humic humic JJ cord-338585-ep9r1n8t 64 5 matter matter NN cord-338585-ep9r1n8t 64 6 by by IN cord-338585-ep9r1n8t 64 7 effect effect NN cord-338585-ep9r1n8t 64 8 of of IN cord-338585-ep9r1n8t 64 9 amine amine NN cord-338585-ep9r1n8t 64 10 acids acid NNS cord-338585-ep9r1n8t 64 11 on on IN cord-338585-ep9r1n8t 64 12 sugar sugar NN cord-338585-ep9r1n8t 64 13 reducing reduce VBG cord-338585-ep9r1n8t 64 14 agents agent NNS cord-338585-ep9r1n8t 64 15 Pyridinium Pyridinium NNP cord-338585-ep9r1n8t 64 16 - - HYPH cord-338585-ep9r1n8t 64 17 carbaldehyde carbaldehyde NNP cord-338585-ep9r1n8t 64 18 : : : cord-338585-ep9r1n8t 65 1 active active JJ cord-338585-ep9r1n8t 65 2 Maillard Maillard NNP cord-338585-ep9r1n8t 65 3 reaction reaction NN cord-338585-ep9r1n8t 65 4 product product NN cord-338585-ep9r1n8t 65 5 from from IN cord-338585-ep9r1n8t 65 6 the the DT cord-338585-ep9r1n8t 65 7 reaction reaction NN cord-338585-ep9r1n8t 65 8 of of IN cord-338585-ep9r1n8t 65 9 hexoses hexose NNS cord-338585-ep9r1n8t 65 10 with with IN cord-338585-ep9r1n8t 65 11 lysine lysine NN cord-338585-ep9r1n8t 65 12 residues residue NNS cord-338585-ep9r1n8t 65 13 3-hydroxypyridine 3-hydroxypyridine CD cord-338585-ep9r1n8t 65 14 chromophores chromophore NNS cord-338585-ep9r1n8t 65 15 are be VBP cord-338585-ep9r1n8t 65 16 endogenous endogenous JJ cord-338585-ep9r1n8t 65 17 sensitizers sensitizer NNS cord-338585-ep9r1n8t 65 18 of of IN cord-338585-ep9r1n8t 65 19 photooxidative photooxidative JJ cord-338585-ep9r1n8t 65 20 stress stress NN cord-338585-ep9r1n8t 65 21 in in IN cord-338585-ep9r1n8t 65 22 human human JJ cord-338585-ep9r1n8t 65 23 skin skin NN cord-338585-ep9r1n8t 65 24 cells cell NNS cord-338585-ep9r1n8t 65 25 Modificaiton Modificaiton NNP cord-338585-ep9r1n8t 65 26 of of IN cord-338585-ep9r1n8t 65 27 DNA dna NN cord-338585-ep9r1n8t 65 28 by by IN cord-338585-ep9r1n8t 65 29 Reducing reduce VBG cord-338585-ep9r1n8t 65 30 Sugars sugar NNS cord-338585-ep9r1n8t 65 31 -A -A . cord-338585-ep9r1n8t 66 1 possible possible JJ cord-338585-ep9r1n8t 66 2 mechanism mechanism NN cord-338585-ep9r1n8t 66 3 for for IN cord-338585-ep9r1n8t 66 4 nucleic nucleic JJ cord-338585-ep9r1n8t 66 5 acid acid NN cord-338585-ep9r1n8t 66 6 aging aging NN cord-338585-ep9r1n8t 66 7 and and CC cord-338585-ep9r1n8t 66 8 age age NN cord-338585-ep9r1n8t 66 9 - - HYPH cord-338585-ep9r1n8t 66 10 related relate VBN cord-338585-ep9r1n8t 66 11 dysfunction dysfunction NN cord-338585-ep9r1n8t 66 12 in in IN cord-338585-ep9r1n8t 66 13 geneexpression geneexpression NN cord-338585-ep9r1n8t 66 14 Modification Modification NNP cord-338585-ep9r1n8t 66 15 of of IN cord-338585-ep9r1n8t 66 16 DNA DNA NNP cord-338585-ep9r1n8t 66 17 by by IN cord-338585-ep9r1n8t 66 18 Glucose-6-phosphate Glucose-6-phosphate NNP cord-338585-ep9r1n8t 66 19 Induces induce VBZ cord-338585-ep9r1n8t 66 20 DNA DNA NNP cord-338585-ep9r1n8t 66 21 Rearrangements rearrangement NNS cord-338585-ep9r1n8t 66 22 in in IN cord-338585-ep9r1n8t 66 23 an an DT cord-338585-ep9r1n8t 66 24 Escherichia escherichia NN cord-338585-ep9r1n8t 66 25 - - HYPH cord-338585-ep9r1n8t 66 26 coli coli NNS cord-338585-ep9r1n8t 66 27 Plasmide Plasmide NNP cord-338585-ep9r1n8t 66 28 Reaction reaction NN cord-338585-ep9r1n8t 66 29 of of IN cord-338585-ep9r1n8t 66 30 guanosine guanosine NN cord-338585-ep9r1n8t 66 31 with with IN cord-338585-ep9r1n8t 66 32 glucose glucose NN cord-338585-ep9r1n8t 66 33 under under IN cord-338585-ep9r1n8t 66 34 oxidative oxidative JJ cord-338585-ep9r1n8t 66 35 conditions condition NNS cord-338585-ep9r1n8t 67 1 The the DT cord-338585-ep9r1n8t 67 2 formaiton formaiton NN cord-338585-ep9r1n8t 67 3 of of IN cord-338585-ep9r1n8t 67 4 reactive reactive JJ cord-338585-ep9r1n8t 67 5 intermediate(s intermediate(s NNP cord-338585-ep9r1n8t 67 6 ) ) -RRB- cord-338585-ep9r1n8t 67 7 of of IN cord-338585-ep9r1n8t 67 8 gluocose-6-phosphate gluocose-6-phosphate NN cord-338585-ep9r1n8t 67 9 and and CC cord-338585-ep9r1n8t 67 10 lysine lysine NN cord-338585-ep9r1n8t 67 11 capable capable JJ cord-338585-ep9r1n8t 67 12 of of IN cord-338585-ep9r1n8t 67 13 rapidly rapidly RB cord-338585-ep9r1n8t 67 14 reacting react VBG cord-338585-ep9r1n8t 67 15 with with IN cord-338585-ep9r1n8t 67 16 DNA dna NN cord-338585-ep9r1n8t 67 17 Vitro vitro FW cord-338585-ep9r1n8t 67 18 Antifungal Antifungal NNP cord-338585-ep9r1n8t 67 19 Activity activity NN cord-338585-ep9r1n8t 67 20 of of IN cord-338585-ep9r1n8t 67 21 Dihydroxyacetone Dihydroxyacetone NNP cord-338585-ep9r1n8t 67 22 Against against IN cord-338585-ep9r1n8t 67 23 Causative causative JJ cord-338585-ep9r1n8t 67 24 Agents agent NNS cord-338585-ep9r1n8t 67 25 of of IN cord-338585-ep9r1n8t 67 26 Dermatomycosis Dermatomycosis NNP cord-338585-ep9r1n8t 67 27 Stability Stability NNP cord-338585-ep9r1n8t 67 28 of of IN cord-338585-ep9r1n8t 67 29 human human JJ cord-338585-ep9r1n8t 67 30 metapneumovirus metapneumovirus NNP cord-338585-ep9r1n8t 67 31 and and CC cord-338585-ep9r1n8t 67 32 human human JJ cord-338585-ep9r1n8t 67 33 coronavirus coronavirus NN cord-338585-ep9r1n8t 68 1 NL63 NL63 NNP cord-338585-ep9r1n8t 69 1 on on IN cord-338585-ep9r1n8t 69 2 medical medical JJ cord-338585-ep9r1n8t 69 3 instruments instrument NNS cord-338585-ep9r1n8t 69 4 and and CC cord-338585-ep9r1n8t 69 5 in in IN cord-338585-ep9r1n8t 69 6 the the DT cord-338585-ep9r1n8t 69 7 patient patient JJ cord-338585-ep9r1n8t 69 8 environment environment NN cord-338585-ep9r1n8t 69 9 I -PRON- PRP cord-338585-ep9r1n8t 69 10 attest attest VBP cord-338585-ep9r1n8t 69 11 that that IN cord-338585-ep9r1n8t 69 12 I -PRON- PRP cord-338585-ep9r1n8t 69 13 have have VBP cord-338585-ep9r1n8t 69 14 no no DT cord-338585-ep9r1n8t 69 15 conflicts conflict NNS cord-338585-ep9r1n8t 69 16 in in IN cord-338585-ep9r1n8t 69 17 submitting submit VBG cord-338585-ep9r1n8t 69 18 this this DT cord-338585-ep9r1n8t 69 19 work work NN cord-338585-ep9r1n8t 69 20 . . .